-- dump date   	20140619_085349
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1133853000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1133853000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1133853000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853000004	Walker A motif; other site
1133853000005	ATP binding site [chemical binding]; other site
1133853000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1133853000007	Walker B motif; other site
1133853000008	arginine finger; other site
1133853000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1133853000010	DnaA box-binding interface [nucleotide binding]; other site
1133853000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1133853000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1133853000013	putative DNA binding surface [nucleotide binding]; other site
1133853000014	dimer interface [polypeptide binding]; other site
1133853000015	beta-clamp/clamp loader binding surface; other site
1133853000016	beta-clamp/translesion DNA polymerase binding surface; other site
1133853000017	recF protein; Region: recf; TIGR00611
1133853000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853000019	Walker A/P-loop; other site
1133853000020	ATP binding site [chemical binding]; other site
1133853000021	Q-loop/lid; other site
1133853000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853000023	ABC transporter signature motif; other site
1133853000024	Walker B; other site
1133853000025	D-loop; other site
1133853000026	H-loop/switch region; other site
1133853000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1133853000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853000029	Mg2+ binding site [ion binding]; other site
1133853000030	G-X-G motif; other site
1133853000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1133853000032	anchoring element; other site
1133853000033	dimer interface [polypeptide binding]; other site
1133853000034	ATP binding site [chemical binding]; other site
1133853000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1133853000036	active site
1133853000037	putative metal-binding site [ion binding]; other site
1133853000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1133853000039	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853000040	hypothetical protein; Provisional; Region: PRK11426
1133853000041	sugar phosphate phosphatase; Provisional; Region: PRK10513
1133853000042	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853000043	active site
1133853000044	motif I; other site
1133853000045	motif II; other site
1133853000046	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853000047	hypothetical protein; Provisional; Region: PRK10215
1133853000048	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1133853000049	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853000050	DNA-binding site [nucleotide binding]; DNA binding site
1133853000051	FCD domain; Region: FCD; pfam07729
1133853000052	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1133853000053	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1133853000054	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1133853000055	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1133853000056	active site
1133853000057	intersubunit interface [polypeptide binding]; other site
1133853000058	catalytic residue [active]
1133853000059	galactonate dehydratase; Provisional; Region: PRK14017
1133853000060	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1133853000061	putative active site pocket [active]
1133853000062	putative metal binding site [ion binding]; other site
1133853000063	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000064	D-galactonate transporter; Region: 2A0114; TIGR00893
1133853000065	putative substrate translocation pore; other site
1133853000066	putative oxidoreductase; Provisional; Region: PRK11445
1133853000067	hypothetical protein; Provisional; Region: PRK07236
1133853000068	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1133853000069	hypothetical protein; Provisional; Region: PRK11616
1133853000070	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1133853000071	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1133853000072	putative dimer interface [polypeptide binding]; other site
1133853000073	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1133853000074	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1133853000075	putative dimer interface [polypeptide binding]; other site
1133853000076	putative transporter; Validated; Region: PRK03818
1133853000077	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1133853000078	TrkA-C domain; Region: TrkA_C; pfam02080
1133853000079	TrkA-C domain; Region: TrkA_C; pfam02080
1133853000080	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1133853000081	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1133853000082	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853000083	DNA-binding site [nucleotide binding]; DNA binding site
1133853000084	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1133853000085	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1133853000086	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1133853000087	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853000088	active site turn [active]
1133853000089	phosphorylation site [posttranslational modification]
1133853000090	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1133853000091	NAD(P) binding site [chemical binding]; other site
1133853000092	LDH/MDH dimer interface [polypeptide binding]; other site
1133853000093	substrate binding site [chemical binding]; other site
1133853000094	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1133853000095	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853000096	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853000097	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853000098	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853000099	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853000100	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853000101	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133853000102	putative transporter; Provisional; Region: PRK10484
1133853000103	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
1133853000104	Na binding site [ion binding]; other site
1133853000105	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1133853000106	Sulfatase; Region: Sulfatase; pfam00884
1133853000107	Predicted membrane protein [Function unknown]; Region: COG2149
1133853000108	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1133853000109	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1133853000110	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1133853000111	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000112	putative substrate translocation pore; other site
1133853000113	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1133853000114	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133853000115	PYR/PP interface [polypeptide binding]; other site
1133853000116	dimer interface [polypeptide binding]; other site
1133853000117	TPP binding site [chemical binding]; other site
1133853000118	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133853000119	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1133853000120	TPP-binding site [chemical binding]; other site
1133853000121	dimer interface [polypeptide binding]; other site
1133853000122	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1133853000123	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1133853000124	putative valine binding site [chemical binding]; other site
1133853000125	dimer interface [polypeptide binding]; other site
1133853000126	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1133853000127	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853000128	active site
1133853000129	phosphorylation site [posttranslational modification]
1133853000130	intermolecular recognition site; other site
1133853000131	dimerization interface [polypeptide binding]; other site
1133853000132	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853000133	DNA binding residues [nucleotide binding]
1133853000134	dimerization interface [polypeptide binding]; other site
1133853000135	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1133853000136	MASE1; Region: MASE1; pfam05231
1133853000137	Histidine kinase; Region: HisKA_3; pfam07730
1133853000138	regulatory protein UhpC; Provisional; Region: PRK11663
1133853000139	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000140	putative substrate translocation pore; other site
1133853000141	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1133853000142	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000143	putative substrate translocation pore; other site
1133853000144	cryptic adenine deaminase; Provisional; Region: PRK10027
1133853000145	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1133853000146	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1133853000147	active site
1133853000148	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1133853000149	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133853000150	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1133853000151	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1133853000152	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000153	putative substrate translocation pore; other site
1133853000154	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1133853000155	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1133853000156	lipoprotein, YaeC family; Region: TIGR00363
1133853000157	EamA-like transporter family; Region: EamA; pfam00892
1133853000158	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1133853000159	EamA-like transporter family; Region: EamA; pfam00892
1133853000160	sugar efflux transporter; Region: 2A0120; TIGR00899
1133853000161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000162	putative substrate translocation pore; other site
1133853000163	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1133853000164	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133853000165	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133853000166	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133853000167	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133853000168	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133853000169	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133853000170	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133853000171	MPN+ (JAMM) motif; other site
1133853000172	Zinc-binding site [ion binding]; other site
1133853000173	Antirestriction protein; Region: Antirestrict; pfam03230
1133853000174	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133853000175	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1133853000176	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133853000177	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133853000178	hypothetical protein; Provisional; Region: PRK09945
1133853000179	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133853000180	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853000181	Autotransporter beta-domain; Region: Autotransporter; smart00869
1133853000182	Predicted GTPase [General function prediction only]; Region: COG3596
1133853000183	YfjP GTPase; Region: YfjP; cd11383
1133853000184	G1 box; other site
1133853000185	GTP/Mg2+ binding site [chemical binding]; other site
1133853000186	Switch I region; other site
1133853000187	G2 box; other site
1133853000188	Switch II region; other site
1133853000189	G3 box; other site
1133853000190	G4 box; other site
1133853000191	G5 box; other site
1133853000192	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1133853000193	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1133853000194	Haemolysin expression modulating protein; Region: HHA; pfam05321
1133853000195	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133853000196	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853000197	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853000198	Integrase core domain; Region: rve; pfam00665
1133853000199	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133853000200	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853000201	Integrase core domain; Region: rve; pfam00665
1133853000202	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; pfam04655
1133853000203	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
1133853000204	Phosphotransferase enzyme family; Region: APH; pfam01636
1133853000205	active site
1133853000206	ATP binding site [chemical binding]; other site
1133853000207	antibiotic binding site [chemical binding]; other site
1133853000208	dihydropteroate synthase; Region: DHPS; TIGR01496
1133853000209	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1133853000210	substrate binding pocket [chemical binding]; other site
1133853000211	dimer interface [polypeptide binding]; other site
1133853000212	inhibitor binding site; inhibition site
1133853000213	Replication protein C (RepC); Region: RepC; pfam06504
1133853000214	Hexameric Replicative Helicase RepA.  RepA is encoded by a plasmid, which is found in most Gram negative bacteria. RepA is a 5'-3' DNA helicase which can utilize ATP, GTP and CTP to a lesser extent; Region: repA; cd01125
1133853000215	AAA domain; Region: AAA_25; pfam13481
1133853000216	hexamer interface [polypeptide binding]; other site
1133853000217	NTP binding site [chemical binding]; other site
1133853000218	Walker B motif; other site
1133853000219	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133853000220	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853000221	Integrase core domain; Region: rve; pfam00665
1133853000222	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1133853000223	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1133853000224	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1133853000225	beta-lactamase TEM; Provisional; Region: PRK15442
1133853000226	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1133853000227	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
1133853000228	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133853000229	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853000230	Integrase core domain; Region: rve; pfam00665
1133853000231	Domain of unknown function (DUF3330); Region: DUF3330; pfam11809
1133853000232	valyl-tRNA synthetase-like protein; Provisional; Region: PTZ00419
1133853000233	integrase/recombinase; Provisional; Region: PRK15417
1133853000234	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
1133853000235	Int/Topo IB signature motif; other site
1133853000236	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1133853000237	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1133853000238	folate binding site [chemical binding]; other site
1133853000239	NADP+ binding site [chemical binding]; other site
1133853000240	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
1133853000241	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1133853000242	dihydropteroate synthase; Region: DHPS; TIGR01496
1133853000243	substrate binding pocket [chemical binding]; other site
1133853000244	dimer interface [polypeptide binding]; other site
1133853000245	inhibitor binding site; inhibition site
1133853000246	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133853000247	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853000248	Integrase core domain; Region: rve; pfam00665
1133853000249	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133853000250	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1133853000251	catalytic residues [active]
1133853000252	catalytic nucleophile [active]
1133853000253	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133853000254	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133853000255	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133853000256	Synaptic Site I dimer interface [polypeptide binding]; other site
1133853000257	DNA binding site [nucleotide binding]
1133853000258	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1133853000259	DNA-binding interface [nucleotide binding]; DNA binding site
1133853000260	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
1133853000261	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
1133853000262	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853000263	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853000264	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853000265	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853000266	integrase; Provisional; Region: PRK09692
1133853000267	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853000268	active site
1133853000269	Int/Topo IB signature motif; other site
1133853000270	putative transporter; Provisional; Region: PRK11462
1133853000271	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1133853000272	putative alpha-glucosidase; Provisional; Region: PRK10658
1133853000273	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1133853000274	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1133853000275	active site
1133853000276	homotrimer interface [polypeptide binding]; other site
1133853000277	catalytic site [active]
1133853000278	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1133853000279	AsmA family; Region: AsmA; pfam05170
1133853000280	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1133853000281	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1133853000282	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1133853000283	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1133853000284	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1133853000285	generic binding surface II; other site
1133853000286	ssDNA binding site; other site
1133853000287	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853000288	ATP binding site [chemical binding]; other site
1133853000289	putative Mg++ binding site [ion binding]; other site
1133853000290	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853000291	nucleotide binding region [chemical binding]; other site
1133853000292	ATP-binding site [chemical binding]; other site
1133853000293	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1133853000294	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1133853000295	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1133853000296	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1133853000297	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133853000298	Zn2+ binding site [ion binding]; other site
1133853000299	Mg2+ binding site [ion binding]; other site
1133853000300	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1133853000301	synthetase active site [active]
1133853000302	NTP binding site [chemical binding]; other site
1133853000303	metal binding site [ion binding]; metal-binding site
1133853000304	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1133853000305	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1133853000306	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1133853000307	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1133853000308	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1133853000309	catalytic site [active]
1133853000310	G-X2-G-X-G-K; other site
1133853000311	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1133853000312	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1133853000313	nucleotide binding pocket [chemical binding]; other site
1133853000314	K-X-D-G motif; other site
1133853000315	catalytic site [active]
1133853000316	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1133853000317	Predicted membrane protein [Function unknown]; Region: COG2860
1133853000318	UPF0126 domain; Region: UPF0126; pfam03458
1133853000319	UPF0126 domain; Region: UPF0126; pfam03458
1133853000320	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
1133853000321	BRO family, N-terminal domain; Region: Bro-N; pfam02498
1133853000322	hypothetical protein; Provisional; Region: PRK11820
1133853000323	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1133853000324	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1133853000325	ribonuclease PH; Reviewed; Region: rph; PRK00173
1133853000326	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1133853000327	hexamer interface [polypeptide binding]; other site
1133853000328	active site
1133853000329	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853000330	active site
1133853000331	division inhibitor protein; Provisional; Region: slmA; PRK09480
1133853000332	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853000333	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1133853000334	trimer interface [polypeptide binding]; other site
1133853000335	active site
1133853000336	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1133853000337	Flavoprotein; Region: Flavoprotein; pfam02441
1133853000338	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1133853000339	hypothetical protein; Reviewed; Region: PRK00024
1133853000340	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133853000341	MPN+ (JAMM) motif; other site
1133853000342	Zinc-binding site [ion binding]; other site
1133853000343	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1133853000344	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1133853000345	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1133853000346	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1133853000347	DNA binding site [nucleotide binding]
1133853000348	catalytic residue [active]
1133853000349	H2TH interface [polypeptide binding]; other site
1133853000350	putative catalytic residues [active]
1133853000351	turnover-facilitating residue; other site
1133853000352	intercalation triad [nucleotide binding]; other site
1133853000353	8OG recognition residue [nucleotide binding]; other site
1133853000354	putative reading head residues; other site
1133853000355	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1133853000356	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1133853000357	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1133853000358	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1133853000359	active site
1133853000360	(T/H)XGH motif; other site
1133853000361	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1133853000362	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1133853000363	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1133853000364	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1133853000365	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1133853000366	putative active site [active]
1133853000367	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1133853000368	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1133853000369	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1133853000370	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1133853000371	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1133853000372	Ligand binding site; other site
1133853000373	metal-binding site
1133853000374	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1133853000375	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; cl17526
1133853000376	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1133853000377	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1133853000378	Ligand binding site; other site
1133853000379	metal-binding site
1133853000380	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1133853000381	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1133853000382	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1133853000383	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1133853000384	O-antigen ligase RfaL; Provisional; Region: PRK15487
1133853000385	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1133853000386	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1133853000387	putative active site [active]
1133853000388	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1133853000389	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1133853000390	putative active site [active]
1133853000391	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1133853000392	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1133853000393	NADP binding site [chemical binding]; other site
1133853000394	homopentamer interface [polypeptide binding]; other site
1133853000395	substrate binding site [chemical binding]; other site
1133853000396	active site
1133853000397	hypothetical protein; Provisional; Region: PRK11346
1133853000398	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1133853000399	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1133853000400	substrate-cofactor binding pocket; other site
1133853000401	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853000402	catalytic residue [active]
1133853000403	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1133853000404	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133853000405	NAD(P) binding site [chemical binding]; other site
1133853000406	putative glycosyl transferase; Provisional; Region: PRK10073
1133853000407	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1133853000408	active site
1133853000409	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1133853000410	NodB motif; other site
1133853000411	putative active site [active]
1133853000412	putative catalytic site [active]
1133853000413	Zn binding site [ion binding]; other site
1133853000414	AmiB activator; Provisional; Region: PRK11637
1133853000415	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1133853000416	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133853000417	phosphoglyceromutase; Provisional; Region: PRK05434
1133853000418	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1133853000419	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1133853000420	active site residue [active]
1133853000421	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1133853000422	GSH binding site [chemical binding]; other site
1133853000423	catalytic residues [active]
1133853000424	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1133853000425	SecA binding site; other site
1133853000426	Preprotein binding site; other site
1133853000427	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1133853000428	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1133853000429	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1133853000430	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1133853000431	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1133853000432	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1133853000433	trimer interface [polypeptide binding]; other site
1133853000434	active site
1133853000435	substrate binding site [chemical binding]; other site
1133853000436	CoA binding site [chemical binding]; other site
1133853000437	putative rRNA methylase; Provisional; Region: PRK10358
1133853000438	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1133853000439	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1133853000440	phosphate binding site [ion binding]; other site
1133853000441	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1133853000442	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853000443	DNA-binding site [nucleotide binding]; DNA binding site
1133853000444	FCD domain; Region: FCD; pfam07729
1133853000445	L-lactate permease; Provisional; Region: PRK10420
1133853000446	glycolate transporter; Provisional; Region: PRK09695
1133853000447	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133853000448	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1133853000449	trimer interface [polypeptide binding]; other site
1133853000450	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1133853000451	trimer interface [polypeptide binding]; other site
1133853000452	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1133853000453	Haemagglutinin; Region: HIM; pfam05662
1133853000454	Haemagglutinin; Region: HIM; pfam05662
1133853000455	YadA-like C-terminal region; Region: YadA; pfam03895
1133853000456	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1133853000457	hypothetical protein; Provisional; Region: PRK11020
1133853000458	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1133853000459	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1133853000460	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1133853000461	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133853000462	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133853000463	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1133853000464	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1133853000465	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1133853000466	active site
1133853000467	P-loop; other site
1133853000468	phosphorylation site [posttranslational modification]
1133853000469	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853000470	active site
1133853000471	phosphorylation site [posttranslational modification]
1133853000472	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1133853000473	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1133853000474	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853000475	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853000476	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133853000477	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853000478	RHS protein; Region: RHS; pfam03527
1133853000479	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853000480	putative lyase; Provisional; Region: PRK09687
1133853000481	PAAR motif; Region: PAAR_motif; cl15808
1133853000482	RHS Repeat; Region: RHS_repeat; pfam05593
1133853000483	RHS Repeat; Region: RHS_repeat; pfam05593
1133853000484	RHS Repeat; Region: RHS_repeat; cl11982
1133853000485	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853000486	RHS Repeat; Region: RHS_repeat; pfam05593
1133853000487	RHS Repeat; Region: RHS_repeat; pfam05593
1133853000488	RHS protein; Region: RHS; pfam03527
1133853000489	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853000490	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1133853000491	putative glutathione S-transferase; Provisional; Region: PRK10357
1133853000492	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1133853000493	putative C-terminal domain interface [polypeptide binding]; other site
1133853000494	putative GSH binding site (G-site) [chemical binding]; other site
1133853000495	putative dimer interface [polypeptide binding]; other site
1133853000496	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1133853000497	dimer interface [polypeptide binding]; other site
1133853000498	N-terminal domain interface [polypeptide binding]; other site
1133853000499	putative substrate binding pocket (H-site) [chemical binding]; other site
1133853000500	selenocysteine synthase; Provisional; Region: PRK04311
1133853000501	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1133853000502	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1133853000503	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853000504	catalytic residue [active]
1133853000505	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1133853000506	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1133853000507	G1 box; other site
1133853000508	putative GEF interaction site [polypeptide binding]; other site
1133853000509	GTP/Mg2+ binding site [chemical binding]; other site
1133853000510	Switch I region; other site
1133853000511	G2 box; other site
1133853000512	G3 box; other site
1133853000513	Switch II region; other site
1133853000514	G4 box; other site
1133853000515	G5 box; other site
1133853000516	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1133853000517	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1133853000518	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1133853000519	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1133853000520	putative alcohol dehydrogenase; Provisional; Region: PRK09860
1133853000521	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1133853000522	dimer interface [polypeptide binding]; other site
1133853000523	active site
1133853000524	metal binding site [ion binding]; metal-binding site
1133853000525	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1133853000526	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1133853000527	NAD(P) binding site [chemical binding]; other site
1133853000528	catalytic residues [active]
1133853000529	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1133853000530	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1133853000531	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853000532	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853000533	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853000534	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853000535	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853000536	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1133853000537	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1133853000538	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133853000539	intersubunit interface [polypeptide binding]; other site
1133853000540	active site
1133853000541	Zn2+ binding site [ion binding]; other site
1133853000542	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1133853000543	Metal-binding active site; metal-binding site
1133853000544	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853000545	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853000546	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853000547	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853000548	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; cl17274
1133853000549	DctM-like transporters; Region: DctM; pfam06808
1133853000550	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1133853000551	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
1133853000552	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1133853000553	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1133853000554	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133853000555	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133853000556	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133853000557	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1133853000558	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853000559	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1133853000560	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853000561	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853000562	homodimer interface [polypeptide binding]; other site
1133853000563	catalytic residue [active]
1133853000564	potential frameshift: common BLAST hit: gi|218697288|ref|YP_002404955.1| periplasmic alpha-amylase
1133853000565	hypothetical protein; Provisional; Region: PRK10356
1133853000566	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1133853000567	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1133853000568	putative dimerization interface [polypeptide binding]; other site
1133853000569	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133853000570	putative ligand binding site [chemical binding]; other site
1133853000571	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853000572	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853000573	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853000574	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853000575	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853000576	TM-ABC transporter signature motif; other site
1133853000577	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1133853000578	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853000579	Walker A/P-loop; other site
1133853000580	ATP binding site [chemical binding]; other site
1133853000581	Q-loop/lid; other site
1133853000582	ABC transporter signature motif; other site
1133853000583	Walker B; other site
1133853000584	D-loop; other site
1133853000585	H-loop/switch region; other site
1133853000586	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853000587	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1133853000588	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1133853000589	putative ligand binding site [chemical binding]; other site
1133853000590	xylose isomerase; Provisional; Region: PRK05474
1133853000591	xylose isomerase; Region: xylose_isom_A; TIGR02630
1133853000592	xylulokinase; Provisional; Region: PRK15027
1133853000593	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1133853000594	N- and C-terminal domain interface [polypeptide binding]; other site
1133853000595	active site
1133853000596	MgATP binding site [chemical binding]; other site
1133853000597	catalytic site [active]
1133853000598	metal binding site [ion binding]; metal-binding site
1133853000599	xylulose binding site [chemical binding]; other site
1133853000600	homodimer interface [polypeptide binding]; other site
1133853000601	hypothetical protein; Provisional; Region: PRK11403
1133853000602	yiaA/B two helix domain; Region: YiaAB; pfam05360
1133853000603	hypothetical protein; Provisional; Region: PRK11383
1133853000604	yiaA/B two helix domain; Region: YiaAB; pfam05360
1133853000605	yiaA/B two helix domain; Region: YiaAB; pfam05360
1133853000606	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1133853000607	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1133853000608	YsaB-like lipoprotein; Region: YsaB; pfam13983
1133853000609	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1133853000610	dimer interface [polypeptide binding]; other site
1133853000611	motif 1; other site
1133853000612	active site
1133853000613	motif 2; other site
1133853000614	motif 3; other site
1133853000615	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
1133853000616	DALR anticodon binding domain; Region: DALR_1; pfam05746
1133853000617	anticodon binding site; other site
1133853000618	tRNA binding surface [nucleotide binding]; other site
1133853000619	small toxic polypeptide; Provisional; Region: PRK09759
1133853000620	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133853000621	DNA-binding site [nucleotide binding]; DNA binding site
1133853000622	RNA-binding motif; other site
1133853000623	Predicted transcriptional regulator [Transcription]; Region: COG2944
1133853000624	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853000625	non-specific DNA binding site [nucleotide binding]; other site
1133853000626	salt bridge; other site
1133853000627	sequence-specific DNA binding site [nucleotide binding]; other site
1133853000628	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1133853000629	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1133853000630	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1133853000631	dimerization interface [polypeptide binding]; other site
1133853000632	ligand binding site [chemical binding]; other site
1133853000633	NADP binding site [chemical binding]; other site
1133853000634	catalytic site [active]
1133853000635	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1133853000636	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133853000637	ligand binding site [chemical binding]; other site
1133853000638	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1133853000639	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1133853000640	molybdopterin cofactor binding site [chemical binding]; other site
1133853000641	substrate binding site [chemical binding]; other site
1133853000642	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1133853000643	molybdopterin cofactor binding site; other site
1133853000644	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133853000645	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853000646	Coenzyme A binding pocket [chemical binding]; other site
1133853000647	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1133853000648	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1133853000649	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1133853000650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000651	putative substrate translocation pore; other site
1133853000652	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1133853000653	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1133853000654	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853000655	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853000656	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
1133853000657	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853000658	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853000659	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853000660	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
1133853000661	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
1133853000662	phosphoethanolamine transferase; Provisional; Region: PRK11560
1133853000663	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1133853000664	Sulfatase; Region: Sulfatase; pfam00884
1133853000665	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1133853000666	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1133853000667	peptide binding site [polypeptide binding]; other site
1133853000668	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1133853000669	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853000670	dimer interface [polypeptide binding]; other site
1133853000671	conserved gate region; other site
1133853000672	putative PBP binding loops; other site
1133853000673	ABC-ATPase subunit interface; other site
1133853000674	dipeptide transporter; Provisional; Region: PRK10913
1133853000675	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133853000676	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853000677	dimer interface [polypeptide binding]; other site
1133853000678	conserved gate region; other site
1133853000679	putative PBP binding loops; other site
1133853000680	ABC-ATPase subunit interface; other site
1133853000681	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1133853000682	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853000683	Walker A/P-loop; other site
1133853000684	ATP binding site [chemical binding]; other site
1133853000685	Q-loop/lid; other site
1133853000686	ABC transporter signature motif; other site
1133853000687	Walker B; other site
1133853000688	D-loop; other site
1133853000689	H-loop/switch region; other site
1133853000690	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1133853000691	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1133853000692	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853000693	Walker A/P-loop; other site
1133853000694	ATP binding site [chemical binding]; other site
1133853000695	Q-loop/lid; other site
1133853000696	ABC transporter signature motif; other site
1133853000697	Walker B; other site
1133853000698	D-loop; other site
1133853000699	H-loop/switch region; other site
1133853000700	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1133853000701	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133853000702	serine transporter; Region: stp; TIGR00814
1133853000703	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133853000704	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133853000705	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133853000706	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
1133853000707	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
1133853000708	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1133853000709	cell division protein; Provisional; Region: PRK10037
1133853000710	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1133853000711	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1133853000712	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1133853000713	DXD motif; other site
1133853000714	PilZ domain; Region: PilZ; pfam07238
1133853000715	cellulose synthase regulator protein; Provisional; Region: PRK11114
1133853000716	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1133853000717	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1133853000718	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853000719	binding surface
1133853000720	TPR motif; other site
1133853000721	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853000722	binding surface
1133853000723	TPR motif; other site
1133853000724	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1133853000725	putative diguanylate cyclase; Provisional; Region: PRK13561
1133853000726	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853000727	metal binding site [ion binding]; metal-binding site
1133853000728	active site
1133853000729	I-site; other site
1133853000730	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853000731	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1133853000732	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1133853000733	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1133853000734	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133853000735	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853000736	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1133853000737	substrate binding site [chemical binding]; other site
1133853000738	ATP binding site [chemical binding]; other site
1133853000739	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853000740	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1133853000741	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133853000742	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000743	metabolite-proton symporter; Region: 2A0106; TIGR00883
1133853000744	putative substrate translocation pore; other site
1133853000745	inner membrane protein YhjD; Region: TIGR00766
1133853000746	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853000747	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853000748	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1133853000749	putative effector binding pocket; other site
1133853000750	putative dimerization interface [polypeptide binding]; other site
1133853000751	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133853000752	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853000753	DNA binding residues [nucleotide binding]
1133853000754	dimerization interface [polypeptide binding]; other site
1133853000755	trehalase; Provisional; Region: treF; PRK13270
1133853000756	Trehalase; Region: Trehalase; pfam01204
1133853000757	Haem-binding domain; Region: Haem_bd; pfam14376
1133853000758	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1133853000759	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1133853000760	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853000761	catalytic residue [active]
1133853000762	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1133853000763	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853000764	transcriptional regulator YdeO; Provisional; Region: PRK09940
1133853000765	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853000766	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1133853000767	Protein export membrane protein; Region: SecD_SecF; cl14618
1133853000768	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
1133853000769	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853000770	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853000771	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853000772	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853000773	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853000774	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853000775	Pyruvate kinase, alpha/beta domain; Region: PK_C; pfam02887
1133853000776	acid-resistance membrane protein; Provisional; Region: PRK10209
1133853000777	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
1133853000778	acid-resistance protein; Provisional; Region: PRK10208
1133853000779	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1133853000780	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1133853000781	MgtC family; Region: MgtC; pfam02308
1133853000782	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133853000783	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853000784	DNA binding residues [nucleotide binding]
1133853000785	dimerization interface [polypeptide binding]; other site
1133853000786	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
1133853000787	Predicted permeases [General function prediction only]; Region: COG0701
1133853000788	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853000789	dimerization interface [polypeptide binding]; other site
1133853000790	putative DNA binding site [nucleotide binding]; other site
1133853000791	putative Zn2+ binding site [ion binding]; other site
1133853000792	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1133853000793	ArsC family; Region: ArsC; pfam03960
1133853000794	catalytic residues [active]
1133853000795	arsenical pump membrane protein; Provisional; Region: PRK15445
1133853000796	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1133853000797	transmembrane helices; other site
1133853000798	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853000799	dimerization interface [polypeptide binding]; other site
1133853000800	putative DNA binding site [nucleotide binding]; other site
1133853000801	putative Zn2+ binding site [ion binding]; other site
1133853000802	glutathione reductase; Validated; Region: PRK06116
1133853000803	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853000804	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853000805	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1133853000806	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1133853000807	oligopeptidase A; Provisional; Region: PRK10911
1133853000808	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1133853000809	active site
1133853000810	Zn binding site [ion binding]; other site
1133853000811	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853000812	S-adenosylmethionine binding site [chemical binding]; other site
1133853000813	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1133853000814	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000815	putative substrate translocation pore; other site
1133853000816	POT family; Region: PTR2; pfam00854
1133853000817	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853000818	Ligand Binding Site [chemical binding]; other site
1133853000819	universal stress protein UspB; Provisional; Region: PRK04960
1133853000820	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1133853000821	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1133853000822	Predicted flavoproteins [General function prediction only]; Region: COG2081
1133853000823	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853000824	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
1133853000825	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
1133853000826	AAA ATPase domain; Region: AAA_16; pfam13191
1133853000827	AAA domain; Region: AAA_22; pfam13401
1133853000828	TniQ; Region: TniQ; pfam06527
1133853000829	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853000830	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853000831	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853000832	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853000833	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853000834	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853000835	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853000836	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853000837	Transposase; Region: HTH_Tnp_1; pfam01527
1133853000838	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853000839	salt bridge; other site
1133853000840	non-specific DNA binding site [nucleotide binding]; other site
1133853000841	sequence-specific DNA binding site [nucleotide binding]; other site
1133853000842	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853000843	Walker A/P-loop; other site
1133853000844	ATP binding site [chemical binding]; other site
1133853000845	AAA ATPase domain; Region: AAA_15; pfam13175
1133853000846	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1133853000847	active site
1133853000848	metal binding site [ion binding]; metal-binding site
1133853000849	Domain of unknown function (DUF305); Region: DUF305; cl17794
1133853000850	sensor kinase CusS; Provisional; Region: PRK09835
1133853000851	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853000852	dimerization interface [polypeptide binding]; other site
1133853000853	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853000854	dimer interface [polypeptide binding]; other site
1133853000855	phosphorylation site [posttranslational modification]
1133853000856	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853000857	ATP binding site [chemical binding]; other site
1133853000858	Mg2+ binding site [ion binding]; other site
1133853000859	G-X-G motif; other site
1133853000860	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
1133853000861	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853000862	active site
1133853000863	phosphorylation site [posttranslational modification]
1133853000864	intermolecular recognition site; other site
1133853000865	dimerization interface [polypeptide binding]; other site
1133853000866	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853000867	DNA binding site [nucleotide binding]
1133853000868	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1133853000869	periplasmic copper-binding protein; Provisional; Region: PRK09838
1133853000870	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1133853000871	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853000872	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1133853000873	Protein of unknown function, DUF; Region: DUF411; cl01142
1133853000874	YHS domain; Region: YHS; pfam04945
1133853000875	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
1133853000876	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133853000877	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853000878	motif II; other site
1133853000879	Protein of unknown function (DUF2933); Region: DUF2933; pfam11666
1133853000880	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133853000881	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
1133853000882	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1133853000883	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1133853000884	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1133853000885	Copper resistance protein B precursor (CopB); Region: CopB; pfam05275
1133853000886	CopC domain; Region: CopC; pfam04234
1133853000887	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1133853000888	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
1133853000889	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853000890	active site
1133853000891	phosphorylation site [posttranslational modification]
1133853000892	intermolecular recognition site; other site
1133853000893	dimerization interface [polypeptide binding]; other site
1133853000894	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853000895	DNA binding site [nucleotide binding]
1133853000896	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1133853000897	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853000898	dimerization interface [polypeptide binding]; other site
1133853000899	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853000900	dimer interface [polypeptide binding]; other site
1133853000901	phosphorylation site [posttranslational modification]
1133853000902	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853000903	ATP binding site [chemical binding]; other site
1133853000904	Mg2+ binding site [ion binding]; other site
1133853000905	G-X-G motif; other site
1133853000906	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
1133853000907	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
1133853000908	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
1133853000909	HlyD family secretion protein; Region: HlyD; pfam00529
1133853000910	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853000911	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853000912	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1133853000913	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133853000914	Walker A/P-loop; other site
1133853000915	ATP binding site [chemical binding]; other site
1133853000916	Q-loop/lid; other site
1133853000917	ABC transporter signature motif; other site
1133853000918	Walker B; other site
1133853000919	D-loop; other site
1133853000920	H-loop/switch region; other site
1133853000921	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133853000922	Walker A/P-loop; other site
1133853000923	ATP binding site [chemical binding]; other site
1133853000924	Q-loop/lid; other site
1133853000925	ABC transporter signature motif; other site
1133853000926	Walker B; other site
1133853000927	D-loop; other site
1133853000928	H-loop/switch region; other site
1133853000929	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133853000930	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1133853000931	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133853000932	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1133853000933	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1133853000934	HicB family; Region: HicB; pfam05534
1133853000935	nickel responsive regulator; Provisional; Region: PRK02967
1133853000936	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1133853000937	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
1133853000938	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853000939	Walker A/P-loop; other site
1133853000940	ATP binding site [chemical binding]; other site
1133853000941	Q-loop/lid; other site
1133853000942	ABC transporter signature motif; other site
1133853000943	Walker B; other site
1133853000944	D-loop; other site
1133853000945	H-loop/switch region; other site
1133853000946	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
1133853000947	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853000948	Walker A/P-loop; other site
1133853000949	ATP binding site [chemical binding]; other site
1133853000950	Q-loop/lid; other site
1133853000951	ABC transporter signature motif; other site
1133853000952	Walker B; other site
1133853000953	D-loop; other site
1133853000954	H-loop/switch region; other site
1133853000955	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133853000956	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
1133853000957	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853000958	dimer interface [polypeptide binding]; other site
1133853000959	conserved gate region; other site
1133853000960	putative PBP binding loops; other site
1133853000961	ABC-ATPase subunit interface; other site
1133853000962	nickel transporter permease NikB; Provisional; Region: PRK10352
1133853000963	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853000964	dimer interface [polypeptide binding]; other site
1133853000965	conserved gate region; other site
1133853000966	putative PBP binding loops; other site
1133853000967	ABC-ATPase subunit interface; other site
1133853000968	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1133853000969	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1133853000970	substrate binding site [chemical binding]; other site
1133853000971	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1133853000972	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1133853000973	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1133853000974	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1133853000975	major facilitator superfamily transporter; Provisional; Region: PRK05122
1133853000976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853000977	putative substrate translocation pore; other site
1133853000978	hypothetical protein; Provisional; Region: PRK11615
1133853000979	hypothetical protein; Provisional; Region: PRK11212
1133853000980	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1133853000981	CPxP  motif; other site
1133853000982	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1133853000983	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133853000984	metal-binding site [ion binding]
1133853000985	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133853000986	Predicted membrane protein [Function unknown]; Region: COG3714
1133853000987	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1133853000988	hypothetical protein; Provisional; Region: PRK10910
1133853000989	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1133853000990	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853000991	S-adenosylmethionine binding site [chemical binding]; other site
1133853000992	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1133853000993	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1133853000994	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1133853000995	P loop; other site
1133853000996	GTP binding site [chemical binding]; other site
1133853000997	cell division protein FtsE; Provisional; Region: PRK10908
1133853000998	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853000999	Walker A/P-loop; other site
1133853001000	ATP binding site [chemical binding]; other site
1133853001001	Q-loop/lid; other site
1133853001002	ABC transporter signature motif; other site
1133853001003	Walker B; other site
1133853001004	D-loop; other site
1133853001005	H-loop/switch region; other site
1133853001006	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1133853001007	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1133853001008	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1133853001009	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133853001010	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133853001011	DNA binding residues [nucleotide binding]
1133853001012	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1133853001013	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1133853001014	dimerization interface [polypeptide binding]; other site
1133853001015	ligand binding site [chemical binding]; other site
1133853001016	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853001017	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1133853001018	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1133853001019	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1133853001020	dimerization interface [polypeptide binding]; other site
1133853001021	ligand binding site [chemical binding]; other site
1133853001022	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853001023	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1133853001024	TM-ABC transporter signature motif; other site
1133853001025	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1133853001026	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1133853001027	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1133853001028	TM-ABC transporter signature motif; other site
1133853001029	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1133853001030	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1133853001031	Walker A/P-loop; other site
1133853001032	ATP binding site [chemical binding]; other site
1133853001033	Q-loop/lid; other site
1133853001034	ABC transporter signature motif; other site
1133853001035	Walker B; other site
1133853001036	D-loop; other site
1133853001037	H-loop/switch region; other site
1133853001038	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1133853001039	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1133853001040	Walker A/P-loop; other site
1133853001041	ATP binding site [chemical binding]; other site
1133853001042	Q-loop/lid; other site
1133853001043	ABC transporter signature motif; other site
1133853001044	Walker B; other site
1133853001045	D-loop; other site
1133853001046	H-loop/switch region; other site
1133853001047	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1133853001048	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1133853001049	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1133853001050	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853001051	dimer interface [polypeptide binding]; other site
1133853001052	conserved gate region; other site
1133853001053	putative PBP binding loops; other site
1133853001054	ABC-ATPase subunit interface; other site
1133853001055	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1133853001056	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853001057	dimer interface [polypeptide binding]; other site
1133853001058	conserved gate region; other site
1133853001059	putative PBP binding loops; other site
1133853001060	ABC-ATPase subunit interface; other site
1133853001061	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1133853001062	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1133853001063	Walker A/P-loop; other site
1133853001064	ATP binding site [chemical binding]; other site
1133853001065	Q-loop/lid; other site
1133853001066	ABC transporter signature motif; other site
1133853001067	Walker B; other site
1133853001068	D-loop; other site
1133853001069	H-loop/switch region; other site
1133853001070	TOBE domain; Region: TOBE_2; pfam08402
1133853001071	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1133853001072	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1133853001073	putative active site [active]
1133853001074	catalytic site [active]
1133853001075	putative metal binding site [ion binding]; other site
1133853001076	hypothetical protein; Provisional; Region: PRK10350
1133853001077	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1133853001078	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1133853001079	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1133853001080	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1133853001081	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853001082	Coenzyme A binding pocket [chemical binding]; other site
1133853001083	putative oxidoreductase; Provisional; Region: PRK10206
1133853001084	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133853001085	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133853001086	Pirin-related protein [General function prediction only]; Region: COG1741
1133853001087	Pirin; Region: Pirin; pfam02678
1133853001088	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1133853001089	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853001090	DNA binding site [nucleotide binding]
1133853001091	domain linker motif; other site
1133853001092	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1133853001093	putative ligand binding site [chemical binding]; other site
1133853001094	putative dimerization interface [polypeptide binding]; other site
1133853001095	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1133853001096	ATP-binding site [chemical binding]; other site
1133853001097	Gluconate-6-phosphate binding site [chemical binding]; other site
1133853001098	Shikimate kinase; Region: SKI; pfam01202
1133853001099	low affinity gluconate transporter; Provisional; Region: PRK10472
1133853001100	gluconate transporter; Region: gntP; TIGR00791
1133853001101	putative antibiotic transporter; Provisional; Region: PRK10739
1133853001102	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1133853001103	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1133853001104	glycogen branching enzyme; Provisional; Region: PRK05402
1133853001105	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1133853001106	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1133853001107	active site
1133853001108	catalytic site [active]
1133853001109	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1133853001110	glycogen debranching enzyme; Provisional; Region: PRK03705
1133853001111	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1133853001112	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1133853001113	active site
1133853001114	catalytic site [active]
1133853001115	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1133853001116	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1133853001117	ligand binding site; other site
1133853001118	oligomer interface; other site
1133853001119	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1133853001120	sulfate 1 binding site; other site
1133853001121	glycogen synthase; Provisional; Region: glgA; PRK00654
1133853001122	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1133853001123	ADP-binding pocket [chemical binding]; other site
1133853001124	homodimer interface [polypeptide binding]; other site
1133853001125	glycogen phosphorylase; Provisional; Region: PRK14986
1133853001126	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1133853001127	homodimer interface [polypeptide binding]; other site
1133853001128	active site pocket [active]
1133853001129	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1133853001130	hypothetical protein; Provisional; Region: PRK09781; cl08057
1133853001131	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1133853001132	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1133853001133	active site residue [active]
1133853001134	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1133853001135	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1133853001136	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1133853001137	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1133853001138	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853001139	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853001140	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1133853001141	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1133853001142	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853001143	Walker A motif; other site
1133853001144	ATP binding site [chemical binding]; other site
1133853001145	Walker B motif; other site
1133853001146	arginine finger; other site
1133853001147	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1133853001148	hypothetical protein; Reviewed; Region: PRK09588
1133853001149	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
1133853001150	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
1133853001151	putative active site [active]
1133853001152	transcriptional regulator MalT; Provisional; Region: PRK04841
1133853001153	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853001154	DNA binding residues [nucleotide binding]
1133853001155	maltodextrin phosphorylase; Provisional; Region: PRK14985
1133853001156	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1133853001157	homodimer interface [polypeptide binding]; other site
1133853001158	active site pocket [active]
1133853001159	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1133853001160	4-alpha-glucanotransferase; Region: malQ; TIGR00217
1133853001161	high-affinity gluconate transporter; Provisional; Region: PRK14984
1133853001162	gluconate transporter; Region: gntP; TIGR00791
1133853001163	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1133853001164	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1133853001165	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1133853001166	DNA utilization protein GntX; Provisional; Region: PRK11595
1133853001167	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853001168	active site
1133853001169	carboxylesterase BioH; Provisional; Region: PRK10349
1133853001170	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1133853001171	putative transposase; Provisional; Region: PRK09857
1133853001172	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133853001173	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1133853001174	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1133853001175	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1133853001176	G1 box; other site
1133853001177	GTP/Mg2+ binding site [chemical binding]; other site
1133853001178	Switch I region; other site
1133853001179	G2 box; other site
1133853001180	G3 box; other site
1133853001181	Switch II region; other site
1133853001182	G4 box; other site
1133853001183	G5 box; other site
1133853001184	Nucleoside recognition; Region: Gate; pfam07670
1133853001185	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1133853001186	Nucleoside recognition; Region: Gate; pfam07670
1133853001187	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1133853001188	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1133853001189	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1133853001190	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1133853001191	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1133853001192	RNA binding site [nucleotide binding]; other site
1133853001193	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1133853001194	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1133853001195	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1133853001196	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1133853001197	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853001198	active site
1133853001199	phosphorylation site [posttranslational modification]
1133853001200	intermolecular recognition site; other site
1133853001201	dimerization interface [polypeptide binding]; other site
1133853001202	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853001203	DNA binding site [nucleotide binding]
1133853001204	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1133853001205	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853001206	dimerization interface [polypeptide binding]; other site
1133853001207	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853001208	dimer interface [polypeptide binding]; other site
1133853001209	phosphorylation site [posttranslational modification]
1133853001210	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853001211	ATP binding site [chemical binding]; other site
1133853001212	G-X-G motif; other site
1133853001213	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853001214	non-specific DNA binding site [nucleotide binding]; other site
1133853001215	salt bridge; other site
1133853001216	sequence-specific DNA binding site [nucleotide binding]; other site
1133853001217	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1133853001218	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1133853001219	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1133853001220	active site
1133853001221	substrate-binding site [chemical binding]; other site
1133853001222	metal-binding site [ion binding]
1133853001223	ATP binding site [chemical binding]; other site
1133853001224	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1133853001225	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1133853001226	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1133853001227	dimerization interface [polypeptide binding]; other site
1133853001228	domain crossover interface; other site
1133853001229	redox-dependent activation switch; other site
1133853001230	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853001231	RNA binding surface [nucleotide binding]; other site
1133853001232	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1133853001233	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853001234	motif II; other site
1133853001235	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1133853001236	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1133853001237	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1133853001238	ADP-ribose binding site [chemical binding]; other site
1133853001239	dimer interface [polypeptide binding]; other site
1133853001240	active site
1133853001241	nudix motif; other site
1133853001242	metal binding site [ion binding]; metal-binding site
1133853001243	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1133853001244	Transglycosylase; Region: Transgly; pfam00912
1133853001245	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1133853001246	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1133853001247	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1133853001248	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1133853001249	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1133853001250	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1133853001251	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133853001252	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1133853001253	shikimate kinase; Reviewed; Region: aroK; PRK00131
1133853001254	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1133853001255	ADP binding site [chemical binding]; other site
1133853001256	magnesium binding site [ion binding]; other site
1133853001257	putative shikimate binding site; other site
1133853001258	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1133853001259	active site
1133853001260	dimer interface [polypeptide binding]; other site
1133853001261	metal binding site [ion binding]; metal-binding site
1133853001262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
1133853001263	cell division protein DamX; Validated; Region: PRK10905
1133853001264	DNA adenine methylase; Provisional; Region: PRK10904
1133853001265	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1133853001266	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1133853001267	substrate binding site [chemical binding]; other site
1133853001268	hexamer interface [polypeptide binding]; other site
1133853001269	metal binding site [ion binding]; metal-binding site
1133853001270	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1133853001271	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853001272	motif II; other site
1133853001273	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1133853001274	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1133853001275	active site
1133853001276	HIGH motif; other site
1133853001277	dimer interface [polypeptide binding]; other site
1133853001278	KMSKS motif; other site
1133853001279	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1133853001280	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
1133853001281	dimer interface [polypeptide binding]; other site
1133853001282	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1133853001283	active site
1133853001284	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133853001285	substrate binding site [chemical binding]; other site
1133853001286	catalytic residue [active]
1133853001287	putative mutase; Provisional; Region: PRK12383
1133853001288	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
1133853001289	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1133853001290	active site
1133853001291	substrate binding pocket [chemical binding]; other site
1133853001292	homodimer interaction site [polypeptide binding]; other site
1133853001293	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
1133853001294	Protein of unknown function; Region: YhfT; pfam10797
1133853001295	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1133853001296	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
1133853001297	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
1133853001298	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853001299	DNA-binding site [nucleotide binding]; DNA binding site
1133853001300	UTRA domain; Region: UTRA; pfam07702
1133853001301	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1133853001302	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853001303	substrate binding site [chemical binding]; other site
1133853001304	ATP binding site [chemical binding]; other site
1133853001305	fructoselysine 3-epimerase; Provisional; Region: PRK09856
1133853001306	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1133853001307	AP (apurinic/apyrimidinic) site pocket; other site
1133853001308	DNA interaction; other site
1133853001309	Metal-binding active site; metal-binding site
1133853001310	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
1133853001311	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1133853001312	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1133853001313	dimer interface [polypeptide binding]; other site
1133853001314	active site
1133853001315	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
1133853001316	hypothetical protein; Provisional; Region: PHA02764
1133853001317	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1133853001318	siroheme synthase; Provisional; Region: cysG; PRK10637
1133853001319	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1133853001320	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1133853001321	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1133853001322	active site
1133853001323	SAM binding site [chemical binding]; other site
1133853001324	homodimer interface [polypeptide binding]; other site
1133853001325	nitrite transporter NirC; Provisional; Region: PRK11562
1133853001326	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1133853001327	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1133853001328	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853001329	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1133853001330	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1133853001331	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1133853001332	putative transporter; Provisional; Region: PRK03699
1133853001333	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853001334	putative substrate translocation pore; other site
1133853001335	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1133853001336	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1133853001337	substrate binding site [chemical binding]; other site
1133853001338	hypothetical protein; Provisional; Region: PRK10204
1133853001339	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1133853001340	cell filamentation protein Fic; Provisional; Region: PRK10347
1133853001341	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1133853001342	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1133853001343	glutamine binding [chemical binding]; other site
1133853001344	catalytic triad [active]
1133853001345	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1133853001346	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853001347	inhibitor-cofactor binding pocket; inhibition site
1133853001348	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853001349	catalytic residue [active]
1133853001350	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1133853001351	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1133853001352	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133853001353	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1133853001354	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1133853001355	ligand binding site [chemical binding]; other site
1133853001356	flexible hinge region; other site
1133853001357	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1133853001358	putative switch regulator; other site
1133853001359	non-specific DNA interactions [nucleotide binding]; other site
1133853001360	DNA binding site [nucleotide binding]
1133853001361	sequence specific DNA binding site [nucleotide binding]; other site
1133853001362	putative cAMP binding site [chemical binding]; other site
1133853001363	hypothetical protein; Provisional; Region: PRK10738
1133853001364	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1133853001365	active site
1133853001366	hypothetical protein; Provisional; Region: PRK04966
1133853001367	putative hydrolase; Provisional; Region: PRK10985
1133853001368	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1133853001369	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853001370	Walker A/P-loop; other site
1133853001371	ATP binding site [chemical binding]; other site
1133853001372	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133853001373	ABC transporter signature motif; other site
1133853001374	Walker B; other site
1133853001375	D-loop; other site
1133853001376	ABC transporter; Region: ABC_tran_2; pfam12848
1133853001377	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133853001378	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1133853001379	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1133853001380	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1133853001381	TrkA-N domain; Region: TrkA_N; pfam02254
1133853001382	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1133853001383	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1133853001384	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133853001385	phi X174 lysis protein; Provisional; Region: PRK02793
1133853001386	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1133853001387	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1133853001388	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133853001389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1133853001390	YheO-like PAS domain; Region: PAS_6; pfam08348
1133853001391	HTH domain; Region: HTH_22; pfam13309
1133853001392	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1133853001393	sulfur relay protein TusC; Validated; Region: PRK00211
1133853001394	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1133853001395	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1133853001396	S17 interaction site [polypeptide binding]; other site
1133853001397	S8 interaction site; other site
1133853001398	16S rRNA interaction site [nucleotide binding]; other site
1133853001399	streptomycin interaction site [chemical binding]; other site
1133853001400	23S rRNA interaction site [nucleotide binding]; other site
1133853001401	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1133853001402	30S ribosomal protein S7; Validated; Region: PRK05302
1133853001403	elongation factor G; Reviewed; Region: PRK00007
1133853001404	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1133853001405	G1 box; other site
1133853001406	putative GEF interaction site [polypeptide binding]; other site
1133853001407	GTP/Mg2+ binding site [chemical binding]; other site
1133853001408	Switch I region; other site
1133853001409	G2 box; other site
1133853001410	G3 box; other site
1133853001411	Switch II region; other site
1133853001412	G4 box; other site
1133853001413	G5 box; other site
1133853001414	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1133853001415	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1133853001416	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1133853001417	elongation factor Tu; Reviewed; Region: PRK00049
1133853001418	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1133853001419	G1 box; other site
1133853001420	GEF interaction site [polypeptide binding]; other site
1133853001421	GTP/Mg2+ binding site [chemical binding]; other site
1133853001422	Switch I region; other site
1133853001423	G2 box; other site
1133853001424	G3 box; other site
1133853001425	Switch II region; other site
1133853001426	G4 box; other site
1133853001427	G5 box; other site
1133853001428	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1133853001429	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1133853001430	Antibiotic Binding Site [chemical binding]; other site
1133853001431	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1133853001432	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1133853001433	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1133853001434	heme binding site [chemical binding]; other site
1133853001435	ferroxidase pore; other site
1133853001436	ferroxidase diiron center [ion binding]; other site
1133853001437	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1133853001438	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1133853001439	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1133853001440	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1133853001441	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1133853001442	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1133853001443	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1133853001444	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1133853001445	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1133853001446	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1133853001447	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1133853001448	protein-rRNA interface [nucleotide binding]; other site
1133853001449	putative translocon binding site; other site
1133853001450	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1133853001451	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1133853001452	G-X-X-G motif; other site
1133853001453	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1133853001454	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1133853001455	23S rRNA interface [nucleotide binding]; other site
1133853001456	5S rRNA interface [nucleotide binding]; other site
1133853001457	putative antibiotic binding site [chemical binding]; other site
1133853001458	L25 interface [polypeptide binding]; other site
1133853001459	L27 interface [polypeptide binding]; other site
1133853001460	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1133853001461	23S rRNA interface [nucleotide binding]; other site
1133853001462	putative translocon interaction site; other site
1133853001463	signal recognition particle (SRP54) interaction site; other site
1133853001464	L23 interface [polypeptide binding]; other site
1133853001465	trigger factor interaction site; other site
1133853001466	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1133853001467	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1133853001468	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1133853001469	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1133853001470	RNA binding site [nucleotide binding]; other site
1133853001471	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1133853001472	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1133853001473	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1133853001474	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1133853001475	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1133853001476	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1133853001477	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1133853001478	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1133853001479	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1133853001480	23S rRNA interface [nucleotide binding]; other site
1133853001481	5S rRNA interface [nucleotide binding]; other site
1133853001482	L27 interface [polypeptide binding]; other site
1133853001483	L5 interface [polypeptide binding]; other site
1133853001484	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1133853001485	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1133853001486	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1133853001487	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1133853001488	23S rRNA binding site [nucleotide binding]; other site
1133853001489	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1133853001490	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1133853001491	SecY translocase; Region: SecY; pfam00344
1133853001492	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1133853001493	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1133853001494	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1133853001495	30S ribosomal protein S11; Validated; Region: PRK05309
1133853001496	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1133853001497	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1133853001498	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853001499	RNA binding surface [nucleotide binding]; other site
1133853001500	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1133853001501	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1133853001502	alphaNTD homodimer interface [polypeptide binding]; other site
1133853001503	alphaNTD - beta interaction site [polypeptide binding]; other site
1133853001504	alphaNTD - beta' interaction site [polypeptide binding]; other site
1133853001505	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1133853001506	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1133853001507	hypothetical protein; Provisional; Region: PRK10203
1133853001508	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1133853001509	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1133853001510	DNA binding residues [nucleotide binding]
1133853001511	dimer interface [polypeptide binding]; other site
1133853001512	metal binding site [ion binding]; metal-binding site
1133853001513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1133853001514	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1133853001515	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
1133853001516	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1133853001517	TrkA-N domain; Region: TrkA_N; pfam02254
1133853001518	TrkA-C domain; Region: TrkA_C; pfam02080
1133853001519	TrkA-N domain; Region: TrkA_N; pfam02254
1133853001520	TrkA-C domain; Region: TrkA_C; pfam02080
1133853001521	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1133853001522	putative RNA binding site [nucleotide binding]; other site
1133853001523	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1133853001524	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853001525	S-adenosylmethionine binding site [chemical binding]; other site
1133853001526	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1133853001527	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1133853001528	putative active site [active]
1133853001529	substrate binding site [chemical binding]; other site
1133853001530	putative cosubstrate binding site; other site
1133853001531	catalytic site [active]
1133853001532	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1133853001533	substrate binding site [chemical binding]; other site
1133853001534	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1133853001535	active site
1133853001536	catalytic residues [active]
1133853001537	metal binding site [ion binding]; metal-binding site
1133853001538	hypothetical protein; Provisional; Region: PRK10736
1133853001539	DNA protecting protein DprA; Region: dprA; TIGR00732
1133853001540	hypothetical protein; Validated; Region: PRK03430
1133853001541	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133853001542	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1133853001543	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133853001544	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133853001545	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1133853001546	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
1133853001547	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1133853001548	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1133853001549	shikimate binding site; other site
1133853001550	NAD(P) binding site [chemical binding]; other site
1133853001551	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1133853001552	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1133853001553	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1133853001554	trimer interface [polypeptide binding]; other site
1133853001555	putative metal binding site [ion binding]; other site
1133853001556	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1133853001557	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133853001558	Walker A/P-loop; other site
1133853001559	ATP binding site [chemical binding]; other site
1133853001560	Q-loop/lid; other site
1133853001561	ABC transporter signature motif; other site
1133853001562	Walker B; other site
1133853001563	D-loop; other site
1133853001564	H-loop/switch region; other site
1133853001565	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853001566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853001567	dimer interface [polypeptide binding]; other site
1133853001568	conserved gate region; other site
1133853001569	putative PBP binding loops; other site
1133853001570	ABC-ATPase subunit interface; other site
1133853001571	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
1133853001572	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853001573	conserved gate region; other site
1133853001574	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853001575	dimer interface [polypeptide binding]; other site
1133853001576	conserved gate region; other site
1133853001577	putative PBP binding loops; other site
1133853001578	ABC-ATPase subunit interface; other site
1133853001579	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1133853001580	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853001581	substrate binding pocket [chemical binding]; other site
1133853001582	membrane-bound complex binding site; other site
1133853001583	hinge residues; other site
1133853001584	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1133853001585	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1133853001586	Protein export membrane protein; Region: SecD_SecF; cl14618
1133853001587	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1133853001588	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853001589	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853001590	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1133853001591	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853001592	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1133853001593	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1133853001594	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1133853001595	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853001596	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133853001597	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1133853001598	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1133853001599	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1133853001600	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1133853001601	FMN binding site [chemical binding]; other site
1133853001602	active site
1133853001603	catalytic residues [active]
1133853001604	substrate binding site [chemical binding]; other site
1133853001605	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1133853001606	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1133853001607	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1133853001608	Na binding site [ion binding]; other site
1133853001609	hypothetical protein; Provisional; Region: PRK10633
1133853001610	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1133853001611	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1133853001612	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1133853001613	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1133853001614	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1133853001615	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1133853001616	carboxyltransferase (CT) interaction site; other site
1133853001617	biotinylation site [posttranslational modification]; other site
1133853001618	Ferric reductase like transmembrane component; Region: Ferric_reduct; cl01043
1133853001619	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1133853001620	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1133853001621	NADP binding site [chemical binding]; other site
1133853001622	dimer interface [polypeptide binding]; other site
1133853001623	regulatory protein CsrD; Provisional; Region: PRK11059
1133853001624	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853001625	metal binding site [ion binding]; metal-binding site
1133853001626	active site
1133853001627	I-site; other site
1133853001628	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853001629	rod shape-determining protein MreB; Provisional; Region: PRK13927
1133853001630	MreB and similar proteins; Region: MreB_like; cd10225
1133853001631	nucleotide binding site [chemical binding]; other site
1133853001632	Mg binding site [ion binding]; other site
1133853001633	putative protofilament interaction site [polypeptide binding]; other site
1133853001634	RodZ interaction site [polypeptide binding]; other site
1133853001635	rod shape-determining protein MreC; Region: mreC; TIGR00219
1133853001636	rod shape-determining protein MreC; Region: MreC; pfam04085
1133853001637	rod shape-determining protein MreD; Provisional; Region: PRK11060
1133853001638	Maf-like protein; Region: Maf; pfam02545
1133853001639	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1133853001640	active site
1133853001641	dimer interface [polypeptide binding]; other site
1133853001642	ribonuclease G; Provisional; Region: PRK11712
1133853001643	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1133853001644	homodimer interface [polypeptide binding]; other site
1133853001645	oligonucleotide binding site [chemical binding]; other site
1133853001646	hypothetical protein; Provisional; Region: PRK10899
1133853001647	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133853001648	protease TldD; Provisional; Region: tldD; PRK10735
1133853001649	transcriptional regulator; Provisional; Region: PRK10632
1133853001650	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853001651	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1133853001652	putative effector binding pocket; other site
1133853001653	dimerization interface [polypeptide binding]; other site
1133853001654	efflux system membrane protein; Provisional; Region: PRK11594
1133853001655	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1133853001656	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853001657	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853001658	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1133853001659	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133853001660	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1133853001661	RNAase interaction site [polypeptide binding]; other site
1133853001662	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853001663	arginine repressor; Provisional; Region: PRK05066
1133853001664	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1133853001665	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1133853001666	malate dehydrogenase; Provisional; Region: PRK05086
1133853001667	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1133853001668	NAD binding site [chemical binding]; other site
1133853001669	dimerization interface [polypeptide binding]; other site
1133853001670	Substrate binding site [chemical binding]; other site
1133853001671	serine endoprotease; Provisional; Region: PRK10898
1133853001672	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1133853001673	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133853001674	serine endoprotease; Provisional; Region: PRK10139
1133853001675	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1133853001676	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133853001677	protein binding site [polypeptide binding]; other site
1133853001678	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133853001679	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1133853001680	hypothetical protein; Provisional; Region: PRK11677
1133853001681	Predicted ATPase [General function prediction only]; Region: COG1485
1133853001682	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1133853001683	23S rRNA interface [nucleotide binding]; other site
1133853001684	L3 interface [polypeptide binding]; other site
1133853001685	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1133853001686	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1133853001687	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1133853001688	C-terminal domain interface [polypeptide binding]; other site
1133853001689	putative GSH binding site (G-site) [chemical binding]; other site
1133853001690	dimer interface [polypeptide binding]; other site
1133853001691	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1133853001692	dimer interface [polypeptide binding]; other site
1133853001693	N-terminal domain interface [polypeptide binding]; other site
1133853001694	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1133853001695	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
1133853001696	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1133853001697	transcriptional regulator NanR; Provisional; Region: PRK03837
1133853001698	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853001699	DNA-binding site [nucleotide binding]; DNA binding site
1133853001700	FCD domain; Region: FCD; pfam07729
1133853001701	N-acetylneuraminate lyase; Region: nanA; TIGR00683
1133853001702	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1133853001703	inhibitor site; inhibition site
1133853001704	active site
1133853001705	dimer interface [polypeptide binding]; other site
1133853001706	catalytic residue [active]
1133853001707	putative sialic acid transporter; Provisional; Region: PRK03893
1133853001708	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853001709	putative substrate translocation pore; other site
1133853001710	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1133853001711	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1133853001712	putative active site cavity [active]
1133853001713	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1133853001714	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853001715	nucleotide binding site [chemical binding]; other site
1133853001716	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1133853001717	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1133853001718	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1133853001719	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1133853001720	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853001721	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853001722	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1133853001723	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1133853001724	active site
1133853001725	dimer interface [polypeptide binding]; other site
1133853001726	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1133853001727	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1133853001728	active site
1133853001729	FMN binding site [chemical binding]; other site
1133853001730	substrate binding site [chemical binding]; other site
1133853001731	3Fe-4S cluster binding site [ion binding]; other site
1133853001732	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1133853001733	domain interface; other site
1133853001734	radical SAM protein, TIGR01212 family; Region: TIGR01212
1133853001735	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853001736	FeS/SAM binding site; other site
1133853001737	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1133853001738	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853001739	putative active site [active]
1133853001740	heme pocket [chemical binding]; other site
1133853001741	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853001742	dimer interface [polypeptide binding]; other site
1133853001743	phosphorylation site [posttranslational modification]
1133853001744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853001745	ATP binding site [chemical binding]; other site
1133853001746	Mg2+ binding site [ion binding]; other site
1133853001747	G-X-G motif; other site
1133853001748	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853001749	active site
1133853001750	phosphorylation site [posttranslational modification]
1133853001751	intermolecular recognition site; other site
1133853001752	dimerization interface [polypeptide binding]; other site
1133853001753	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133853001754	putative binding surface; other site
1133853001755	active site
1133853001756	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1133853001757	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1133853001758	conserved cys residue [active]
1133853001759	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1133853001760	Transglycosylase; Region: Transgly; cl17702
1133853001761	hypothetical protein; Provisional; Region: PRK10345
1133853001762	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133853001763	dimerization domain swap beta strand [polypeptide binding]; other site
1133853001764	regulatory protein interface [polypeptide binding]; other site
1133853001765	active site
1133853001766	regulatory phosphorylation site [posttranslational modification]; other site
1133853001767	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1133853001768	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853001769	active site
1133853001770	phosphorylation site [posttranslational modification]
1133853001771	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1133853001772	30S subunit binding site; other site
1133853001773	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1133853001774	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1133853001775	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1133853001776	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1133853001777	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1133853001778	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1133853001779	Walker A/P-loop; other site
1133853001780	ATP binding site [chemical binding]; other site
1133853001781	Q-loop/lid; other site
1133853001782	ABC transporter signature motif; other site
1133853001783	Walker B; other site
1133853001784	D-loop; other site
1133853001785	H-loop/switch region; other site
1133853001786	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1133853001787	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1133853001788	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1133853001789	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1133853001790	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1133853001791	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1133853001792	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1133853001793	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1133853001794	putative active site [active]
1133853001795	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1133853001796	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1133853001797	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1133853001798	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1133853001799	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1133853001800	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1133853001801	Walker A/P-loop; other site
1133853001802	ATP binding site [chemical binding]; other site
1133853001803	Q-loop/lid; other site
1133853001804	ABC transporter signature motif; other site
1133853001805	Walker B; other site
1133853001806	D-loop; other site
1133853001807	H-loop/switch region; other site
1133853001808	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1133853001809	conserved hypothetical integral membrane protein; Region: TIGR00056
1133853001810	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1133853001811	mce related protein; Region: MCE; pfam02470
1133853001812	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1133853001813	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1133853001814	anti sigma factor interaction site; other site
1133853001815	regulatory phosphorylation site [posttranslational modification]; other site
1133853001816	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1133853001817	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1133853001818	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1133853001819	hinge; other site
1133853001820	active site
1133853001821	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1133853001822	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1133853001823	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1133853001824	substrate binding pocket [chemical binding]; other site
1133853001825	chain length determination region; other site
1133853001826	substrate-Mg2+ binding site; other site
1133853001827	catalytic residues [active]
1133853001828	aspartate-rich region 1; other site
1133853001829	active site lid residues [active]
1133853001830	aspartate-rich region 2; other site
1133853001831	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1133853001832	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1133853001833	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1133853001834	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1133853001835	EamA-like transporter family; Region: EamA; pfam00892
1133853001836	EamA-like transporter family; Region: EamA; pfam00892
1133853001837	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1133853001838	GTP1/OBG; Region: GTP1_OBG; pfam01018
1133853001839	Obg GTPase; Region: Obg; cd01898
1133853001840	G1 box; other site
1133853001841	GTP/Mg2+ binding site [chemical binding]; other site
1133853001842	Switch I region; other site
1133853001843	G2 box; other site
1133853001844	G3 box; other site
1133853001845	Switch II region; other site
1133853001846	G4 box; other site
1133853001847	G5 box; other site
1133853001848	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1133853001849	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1133853001850	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1133853001851	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1133853001852	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1133853001853	RNA-binding protein YhbY; Provisional; Region: PRK10343
1133853001854	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1133853001855	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853001856	S-adenosylmethionine binding site [chemical binding]; other site
1133853001857	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1133853001858	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853001859	Walker A motif; other site
1133853001860	ATP binding site [chemical binding]; other site
1133853001861	Walker B motif; other site
1133853001862	arginine finger; other site
1133853001863	Peptidase family M41; Region: Peptidase_M41; pfam01434
1133853001864	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1133853001865	dihydropteroate synthase; Region: DHPS; TIGR01496
1133853001866	substrate binding pocket [chemical binding]; other site
1133853001867	dimer interface [polypeptide binding]; other site
1133853001868	inhibitor binding site; inhibition site
1133853001869	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1133853001870	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1133853001871	active site
1133853001872	substrate binding site [chemical binding]; other site
1133853001873	metal binding site [ion binding]; metal-binding site
1133853001874	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1133853001875	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1133853001876	Sulfatase; Region: Sulfatase; pfam00884
1133853001877	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1133853001878	ANP binding site [chemical binding]; other site
1133853001879	Substrate Binding Site II [chemical binding]; other site
1133853001880	Substrate Binding Site I [chemical binding]; other site
1133853001881	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1133853001882	Sm and related proteins; Region: Sm_like; cl00259
1133853001883	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1133853001884	putative oligomer interface [polypeptide binding]; other site
1133853001885	putative RNA binding site [nucleotide binding]; other site
1133853001886	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1133853001887	NusA N-terminal domain; Region: NusA_N; pfam08529
1133853001888	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1133853001889	RNA binding site [nucleotide binding]; other site
1133853001890	homodimer interface [polypeptide binding]; other site
1133853001891	NusA-like KH domain; Region: KH_5; pfam13184
1133853001892	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1133853001893	G-X-X-G motif; other site
1133853001894	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1133853001895	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1133853001896	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1133853001897	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1133853001898	translation initiation factor IF-2; Region: IF-2; TIGR00487
1133853001899	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1133853001900	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1133853001901	G1 box; other site
1133853001902	putative GEF interaction site [polypeptide binding]; other site
1133853001903	GTP/Mg2+ binding site [chemical binding]; other site
1133853001904	Switch I region; other site
1133853001905	G2 box; other site
1133853001906	G3 box; other site
1133853001907	Switch II region; other site
1133853001908	G4 box; other site
1133853001909	G5 box; other site
1133853001910	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1133853001911	Translation-initiation factor 2; Region: IF-2; pfam11987
1133853001912	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1133853001913	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1133853001914	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1133853001915	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1133853001916	RNA binding site [nucleotide binding]; other site
1133853001917	active site
1133853001918	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1133853001919	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1133853001920	16S/18S rRNA binding site [nucleotide binding]; other site
1133853001921	S13e-L30e interaction site [polypeptide binding]; other site
1133853001922	25S rRNA binding site [nucleotide binding]; other site
1133853001923	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1133853001924	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1133853001925	RNase E interface [polypeptide binding]; other site
1133853001926	trimer interface [polypeptide binding]; other site
1133853001927	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1133853001928	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1133853001929	RNase E interface [polypeptide binding]; other site
1133853001930	trimer interface [polypeptide binding]; other site
1133853001931	active site
1133853001932	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1133853001933	putative nucleic acid binding region [nucleotide binding]; other site
1133853001934	G-X-X-G motif; other site
1133853001935	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1133853001936	RNA binding site [nucleotide binding]; other site
1133853001937	domain interface; other site
1133853001938	lipoprotein NlpI; Provisional; Region: PRK11189
1133853001939	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853001940	binding surface
1133853001941	TPR motif; other site
1133853001942	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
1133853001943	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133853001944	ATP binding site [chemical binding]; other site
1133853001945	Mg++ binding site [ion binding]; other site
1133853001946	motif III; other site
1133853001947	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853001948	nucleotide binding region [chemical binding]; other site
1133853001949	ATP-binding site [chemical binding]; other site
1133853001950	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1133853001951	putative RNA binding site [nucleotide binding]; other site
1133853001952	tryptophan permease; Provisional; Region: PRK10483
1133853001953	aromatic amino acid transport protein; Region: araaP; TIGR00837
1133853001954	hypothetical protein; Provisional; Region: PRK10508
1133853001955	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1133853001956	putative protease; Provisional; Region: PRK15447
1133853001957	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1133853001958	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1133853001959	Peptidase family U32; Region: Peptidase_U32; pfam01136
1133853001960	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1133853001961	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1133853001962	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853001963	Coenzyme A binding pocket [chemical binding]; other site
1133853001964	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1133853001965	GIY-YIG motif/motif A; other site
1133853001966	putative active site [active]
1133853001967	putative metal binding site [ion binding]; other site
1133853001968	hypothetical protein; Provisional; Region: PRK03467
1133853001969	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1133853001970	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1133853001971	proposed catalytic triad [active]
1133853001972	conserved cys residue [active]
1133853001973	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1133853001974	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1133853001975	NAD binding site [chemical binding]; other site
1133853001976	active site
1133853001977	Predicted permease; Region: DUF318; pfam03773
1133853001978	outer membrane lipoprotein; Provisional; Region: PRK11023
1133853001979	BON domain; Region: BON; pfam04972
1133853001980	BON domain; Region: BON; pfam04972
1133853001981	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1133853001982	dimer interface [polypeptide binding]; other site
1133853001983	active site
1133853001984	TIGR00252 family protein; Region: TIGR00252
1133853001985	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1133853001986	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1133853001987	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1133853001988	putative ligand binding site [chemical binding]; other site
1133853001989	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1133853001990	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1133853001991	putative SAM binding site [chemical binding]; other site
1133853001992	putative homodimer interface [polypeptide binding]; other site
1133853001993	Fimbrial protein; Region: Fimbrial; pfam00419
1133853001994	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133853001995	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853001996	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853001997	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853001998	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133853001999	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853002000	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853002001	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133853002002	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1133853002003	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1133853002004	active site
1133853002005	trimer interface [polypeptide binding]; other site
1133853002006	allosteric site; other site
1133853002007	active site lid [active]
1133853002008	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
1133853002009	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
1133853002010	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1133853002011	active site
1133853002012	phosphorylation site [posttranslational modification]
1133853002013	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
1133853002014	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1133853002015	active site
1133853002016	intersubunit interface [polypeptide binding]; other site
1133853002017	zinc binding site [ion binding]; other site
1133853002018	Na+ binding site [ion binding]; other site
1133853002019	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1133853002020	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1133853002021	dimer interface [polypeptide binding]; other site
1133853002022	active site
1133853002023	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1133853002024	putative active site [active]
1133853002025	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1133853002026	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1133853002027	active site
1133853002028	dimer interface [polypeptide binding]; other site
1133853002029	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1133853002030	active pocket/dimerization site; other site
1133853002031	active site
1133853002032	phosphorylation site [posttranslational modification]
1133853002033	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1133853002034	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1133853002035	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1133853002036	active site
1133853002037	phosphorylation site [posttranslational modification]
1133853002038	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
1133853002039	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
1133853002040	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853002041	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853002042	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
1133853002043	putative regulator PrlF; Provisional; Region: PRK09974
1133853002044	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1133853002045	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1133853002046	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1133853002047	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1133853002048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853002049	D-galactonate transporter; Region: 2A0114; TIGR00893
1133853002050	putative substrate translocation pore; other site
1133853002051	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1133853002052	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1133853002053	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1133853002054	glycerate kinase I; Provisional; Region: PRK10342
1133853002055	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853002056	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853002057	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853002058	hypothetical protein; Provisional; Region: PRK09716
1133853002059	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
1133853002060	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1133853002061	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853002062	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1133853002063	putative substrate binding pocket [chemical binding]; other site
1133853002064	putative dimerization interface [polypeptide binding]; other site
1133853002065	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1133853002066	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1133853002067	tetramer interface [polypeptide binding]; other site
1133853002068	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853002069	catalytic residue [active]
1133853002070	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1133853002071	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133853002072	propionate/acetate kinase; Provisional; Region: PRK12379
1133853002073	Acetokinase family; Region: Acetate_kinase; cl17229
1133853002074	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1133853002075	Pyruvate formate lyase 1; Region: PFL1; cd01678
1133853002076	coenzyme A binding site [chemical binding]; other site
1133853002077	active site
1133853002078	catalytic residues [active]
1133853002079	glycine loop; other site
1133853002080	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1133853002081	homotrimer interaction site [polypeptide binding]; other site
1133853002082	putative active site [active]
1133853002083	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1133853002084	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1133853002085	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1133853002086	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133853002087	serine transporter; Region: stp; TIGR00814
1133853002088	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1133853002089	Pirin-related protein [General function prediction only]; Region: COG1741
1133853002090	Pirin; Region: Pirin; pfam02678
1133853002091	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853002092	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1133853002093	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853002094	dimerization interface [polypeptide binding]; other site
1133853002095	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853002096	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853002097	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853002098	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853002099	Predicted membrane protein [Function unknown]; Region: COG3152
1133853002100	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1133853002101	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1133853002102	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1133853002103	putative dimer interface [polypeptide binding]; other site
1133853002104	N-terminal domain interface [polypeptide binding]; other site
1133853002105	putative substrate binding pocket (H-site) [chemical binding]; other site
1133853002106	Predicted membrane protein [Function unknown]; Region: COG2259
1133853002107	YqjK-like protein; Region: YqjK; pfam13997
1133853002108	Predicted membrane protein [Function unknown]; Region: COG5393
1133853002109	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1133853002110	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1133853002111	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1133853002112	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133853002113	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1133853002114	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1133853002115	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853002116	DNA-binding site [nucleotide binding]; DNA binding site
1133853002117	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853002118	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133853002119	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1133853002120	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
1133853002121	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1133853002122	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853002123	CblD like pilus biogenesis initiator; Region: CblD; cl06460
1133853002124	D-galactonate transporter; Region: 2A0114; TIGR00893
1133853002125	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853002126	putative substrate translocation pore; other site
1133853002127	Glucuronate isomerase; Region: UxaC; pfam02614
1133853002128	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1133853002129	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1133853002130	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1133853002131	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1133853002132	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
1133853002133	serine/threonine transporter SstT; Provisional; Region: PRK13628
1133853002134	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1133853002135	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1133853002136	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1133853002137	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133853002138	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133853002139	putative active site [active]
1133853002140	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1133853002141	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1133853002142	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853002143	S-adenosylmethionine binding site [chemical binding]; other site
1133853002144	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
1133853002145	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853002146	non-specific DNA binding site [nucleotide binding]; other site
1133853002147	salt bridge; other site
1133853002148	sequence-specific DNA binding site [nucleotide binding]; other site
1133853002149	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1133853002150	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1133853002151	active site
1133853002152	FMN binding site [chemical binding]; other site
1133853002153	2,4-decadienoyl-CoA binding site; other site
1133853002154	catalytic residue [active]
1133853002155	4Fe-4S cluster binding site [ion binding]; other site
1133853002156	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1133853002157	alpha-glucosidase; Provisional; Region: PRK10137
1133853002158	Protein of unknown function, DUF608; Region: DUF608; pfam04685
1133853002159	Trehalase; Region: Trehalase; cl17346
1133853002160	inner membrane transporter YjeM; Provisional; Region: PRK15238
1133853002161	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
1133853002162	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1133853002163	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1133853002164	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1133853002165	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1133853002166	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1133853002167	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1133853002168	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853002169	DNA binding site [nucleotide binding]
1133853002170	domain linker motif; other site
1133853002171	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1133853002172	putative dimerization interface [polypeptide binding]; other site
1133853002173	putative ligand binding site [chemical binding]; other site
1133853002174	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1133853002175	dimer interface [polypeptide binding]; other site
1133853002176	putative tRNA-binding site [nucleotide binding]; other site
1133853002177	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1133853002178	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853002179	inhibitor-cofactor binding pocket; inhibition site
1133853002180	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853002181	catalytic residue [active]
1133853002182	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853002183	PAS fold; Region: PAS_3; pfam08447
1133853002184	putative active site [active]
1133853002185	heme pocket [chemical binding]; other site
1133853002186	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1133853002187	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1133853002188	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133853002189	dimer interface [polypeptide binding]; other site
1133853002190	putative CheW interface [polypeptide binding]; other site
1133853002191	Predicted transcriptional regulators [Transcription]; Region: COG1695
1133853002192	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1133853002193	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1133853002194	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1133853002195	FAD binding pocket [chemical binding]; other site
1133853002196	FAD binding motif [chemical binding]; other site
1133853002197	phosphate binding motif [ion binding]; other site
1133853002198	NAD binding pocket [chemical binding]; other site
1133853002199	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1133853002200	active site
1133853002201	SUMO-1 interface [polypeptide binding]; other site
1133853002202	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1133853002203	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1133853002204	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1133853002205	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1133853002206	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133853002207	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1133853002208	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133853002209	DNA binding residues [nucleotide binding]
1133853002210	DNA primase; Validated; Region: dnaG; PRK05667
1133853002211	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1133853002212	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1133853002213	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1133853002214	active site
1133853002215	metal binding site [ion binding]; metal-binding site
1133853002216	interdomain interaction site; other site
1133853002217	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1133853002218	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1133853002219	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1133853002220	UGMP family protein; Validated; Region: PRK09604
1133853002221	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1133853002222	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133853002223	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1133853002224	transmembrane helices; other site
1133853002225	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1133853002226	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1133853002227	transcriptional activator TtdR; Provisional; Region: PRK09801
1133853002228	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853002229	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1133853002230	putative effector binding pocket; other site
1133853002231	putative dimerization interface [polypeptide binding]; other site
1133853002232	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1133853002233	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1133853002234	homooctamer interface [polypeptide binding]; other site
1133853002235	active site
1133853002236	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1133853002237	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1133853002238	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1133853002239	active site
1133853002240	NTP binding site [chemical binding]; other site
1133853002241	metal binding triad [ion binding]; metal-binding site
1133853002242	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1133853002243	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133853002244	Zn2+ binding site [ion binding]; other site
1133853002245	Mg2+ binding site [ion binding]; other site
1133853002246	SH3 domain-containing protein; Provisional; Region: PRK10884
1133853002247	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1133853002248	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1133853002249	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1133853002250	putative active site [active]
1133853002251	putative metal binding residues [ion binding]; other site
1133853002252	signature motif; other site
1133853002253	putative triphosphate binding site [ion binding]; other site
1133853002254	CHAD domain; Region: CHAD; pfam05235
1133853002255	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1133853002256	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1133853002257	metal binding triad; other site
1133853002258	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1133853002259	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1133853002260	metal binding triad; other site
1133853002261	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1133853002262	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1133853002263	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1133853002264	putative ribose interaction site [chemical binding]; other site
1133853002265	putative ADP binding site [chemical binding]; other site
1133853002266	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1133853002267	active site
1133853002268	nucleotide binding site [chemical binding]; other site
1133853002269	HIGH motif; other site
1133853002270	KMSKS motif; other site
1133853002271	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1133853002272	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1133853002273	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1133853002274	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1133853002275	Fimbrial protein; Region: Fimbrial; pfam00419
1133853002276	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133853002277	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853002278	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853002279	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133853002280	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853002281	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853002282	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853002283	putative fimbrial protein; Provisional; Region: PRK09733
1133853002284	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1133853002285	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1133853002286	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1133853002287	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1133853002288	zinc transporter ZupT; Provisional; Region: PRK04201
1133853002289	ZIP Zinc transporter; Region: Zip; pfam02535
1133853002290	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1133853002291	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1133853002292	putative active site [active]
1133853002293	metal binding site [ion binding]; metal-binding site
1133853002294	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1133853002295	hypothetical protein; Provisional; Region: PRK11653
1133853002296	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1133853002297	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1133853002298	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1133853002299	dimer interface [polypeptide binding]; other site
1133853002300	ADP-ribose binding site [chemical binding]; other site
1133853002301	active site
1133853002302	nudix motif; other site
1133853002303	metal binding site [ion binding]; metal-binding site
1133853002304	putative dehydrogenase; Provisional; Region: PRK11039
1133853002305	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1133853002306	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1133853002307	active site
1133853002308	metal binding site [ion binding]; metal-binding site
1133853002309	hexamer interface [polypeptide binding]; other site
1133853002310	esterase YqiA; Provisional; Region: PRK11071
1133853002311	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1133853002312	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1133853002313	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853002314	ATP binding site [chemical binding]; other site
1133853002315	Mg2+ binding site [ion binding]; other site
1133853002316	G-X-G motif; other site
1133853002317	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1133853002318	anchoring element; other site
1133853002319	dimer interface [polypeptide binding]; other site
1133853002320	ATP binding site [chemical binding]; other site
1133853002321	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1133853002322	active site
1133853002323	metal binding site [ion binding]; metal-binding site
1133853002324	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1133853002325	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1133853002326	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1133853002327	sensor protein QseC; Provisional; Region: PRK10337
1133853002328	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853002329	dimer interface [polypeptide binding]; other site
1133853002330	phosphorylation site [posttranslational modification]
1133853002331	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853002332	ATP binding site [chemical binding]; other site
1133853002333	Mg2+ binding site [ion binding]; other site
1133853002334	G-X-G motif; other site
1133853002335	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1133853002336	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853002337	active site
1133853002338	phosphorylation site [posttranslational modification]
1133853002339	intermolecular recognition site; other site
1133853002340	dimerization interface [polypeptide binding]; other site
1133853002341	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853002342	DNA binding site [nucleotide binding]
1133853002343	TIGR00156 family protein; Region: TIGR00156
1133853002344	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1133853002345	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1133853002346	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1133853002347	CAP-like domain; other site
1133853002348	active site
1133853002349	primary dimer interface [polypeptide binding]; other site
1133853002350	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853002351	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1133853002352	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1133853002353	putative acyl-acceptor binding pocket; other site
1133853002354	FtsI repressor; Provisional; Region: PRK10883
1133853002355	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1133853002356	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1133853002357	hypothetical protein; Provisional; Region: PRK01254
1133853002358	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1133853002359	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1133853002360	putative outer membrane lipoprotein; Provisional; Region: PRK09973
1133853002361	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1133853002362	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853002363	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853002364	active site
1133853002365	catalytic tetrad [active]
1133853002366	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1133853002367	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1133853002368	dimer interface [polypeptide binding]; other site
1133853002369	active site
1133853002370	metal binding site [ion binding]; metal-binding site
1133853002371	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1133853002372	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133853002373	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853002374	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853002375	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133853002376	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1133853002377	cystathionine beta-lyase; Provisional; Region: PRK08114
1133853002378	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1133853002379	homodimer interface [polypeptide binding]; other site
1133853002380	substrate-cofactor binding pocket; other site
1133853002381	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853002382	catalytic residue [active]
1133853002383	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1133853002384	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1133853002385	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1133853002386	oxidoreductase; Provisional; Region: PRK07985
1133853002387	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1133853002388	NAD binding site [chemical binding]; other site
1133853002389	metal binding site [ion binding]; metal-binding site
1133853002390	active site
1133853002391	hypothetical protein; Provisional; Region: PRK05208
1133853002392	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853002393	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853002394	active site
1133853002395	catalytic tetrad [active]
1133853002396	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1133853002397	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1133853002398	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1133853002399	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1133853002400	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133853002401	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1133853002402	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1133853002403	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1133853002404	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1133853002405	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1133853002406	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1133853002407	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1133853002408	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1133853002409	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1133853002410	putative substrate-binding site; other site
1133853002411	nickel binding site [ion binding]; other site
1133853002412	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1133853002413	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1133853002414	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1133853002415	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1133853002416	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853002417	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853002418	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853002419	putative S-transferase; Provisional; Region: PRK11752
1133853002420	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1133853002421	C-terminal domain interface [polypeptide binding]; other site
1133853002422	GSH binding site (G-site) [chemical binding]; other site
1133853002423	dimer interface [polypeptide binding]; other site
1133853002424	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1133853002425	dimer interface [polypeptide binding]; other site
1133853002426	N-terminal domain interface [polypeptide binding]; other site
1133853002427	active site
1133853002428	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1133853002429	CHAP domain; Region: CHAP; pfam05257
1133853002430	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1133853002431	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1133853002432	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1133853002433	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1133853002434	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1133853002435	TMP-binding site; other site
1133853002436	ATP-binding site [chemical binding]; other site
1133853002437	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1133853002438	TMP-binding site; other site
1133853002439	ATP-binding site [chemical binding]; other site
1133853002440	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1133853002441	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1133853002442	active site
1133853002443	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1133853002444	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1133853002445	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
1133853002446	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1133853002447	Predicted permeases [General function prediction only]; Region: COG0795
1133853002448	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1133853002449	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1133853002450	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1133853002451	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1133853002452	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853002453	catalytic residue [active]
1133853002454	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133853002455	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133853002456	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133853002457	NAD(P) binding site [chemical binding]; other site
1133853002458	active site
1133853002459	acyl-CoA synthetase; Validated; Region: PRK09192
1133853002460	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
1133853002461	acyl-activating enzyme (AAE) consensus motif; other site
1133853002462	active site
1133853002463	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
1133853002464	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853002465	DNA-binding site [nucleotide binding]; DNA binding site
1133853002466	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853002467	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
1133853002468	FAD binding domain; Region: FAD_binding_4; pfam01565
1133853002469	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
1133853002470	FAD binding domain; Region: FAD_binding_4; pfam01565
1133853002471	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
1133853002472	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853002473	Cysteine-rich domain; Region: CCG; pfam02754
1133853002474	Cysteine-rich domain; Region: CCG; pfam02754
1133853002475	hypothetical protein; Provisional; Region: PRK09732
1133853002476	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
1133853002477	active site
1133853002478	glycolate transporter; Provisional; Region: PRK09695
1133853002479	L-lactate permease; Region: Lactate_perm; cl00701
1133853002480	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
1133853002481	Peptidase M60-like family; Region: M60-like; pfam13402
1133853002482	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1133853002483	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1133853002484	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1133853002485	putative type II secretion protein GspC; Provisional; Region: PRK09681
1133853002486	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1133853002487	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133853002488	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1133853002489	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133853002490	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133853002491	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133853002492	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1133853002493	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1133853002494	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1133853002495	Walker A motif; other site
1133853002496	ATP binding site [chemical binding]; other site
1133853002497	Walker B motif; other site
1133853002498	type II secretion system protein F; Region: GspF; TIGR02120
1133853002499	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133853002500	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133853002501	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1133853002502	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1133853002503	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1133853002504	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
1133853002505	Type II transport protein GspH; Region: GspH; pfam12019
1133853002506	type II secretion system protein I; Region: gspI; TIGR01707
1133853002507	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1133853002508	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1133853002509	type II secretion system protein J; Region: gspJ; TIGR01711
1133853002510	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1133853002511	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1133853002512	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
1133853002513	GspL-like protein; Provisional; Region: PRK09662
1133853002514	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
1133853002515	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133853002516	Herpes virus major capsid protein; Region: Herpes_MCP; pfam03122
1133853002517	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133853002518	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133853002519	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133853002520	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133853002521	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133853002522	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133853002523	MPN+ (JAMM) motif; other site
1133853002524	Zinc-binding site [ion binding]; other site
1133853002525	Antirestriction protein; Region: Antirestrict; pfam03230
1133853002526	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133853002527	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1133853002528	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133853002529	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133853002530	hypothetical protein; Provisional; Region: PRK09945
1133853002531	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133853002532	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853002533	Autotransporter beta-domain; Region: Autotransporter; smart00869
1133853002534	Predicted GTPase [General function prediction only]; Region: COG3596
1133853002535	YfjP GTPase; Region: YfjP; cd11383
1133853002536	G1 box; other site
1133853002537	GTP/Mg2+ binding site [chemical binding]; other site
1133853002538	Switch I region; other site
1133853002539	G2 box; other site
1133853002540	Switch II region; other site
1133853002541	G3 box; other site
1133853002542	G4 box; other site
1133853002543	G5 box; other site
1133853002544	Replication regulatory protein RepB; Region: RepB-RCR_reg; cl11673
1133853002545	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133853002546	Haemolysin expression modulating protein; Region: HHA; pfam05321
1133853002547	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133853002548	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853002549	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853002550	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133853002551	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1133853002552	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1133853002553	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1133853002554	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
1133853002555	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
1133853002556	Part of AAA domain; Region: AAA_19; pfam13245
1133853002557	Family description; Region: UvrD_C_2; pfam13538
1133853002558	PerC transcriptional activator; Region: PerC; pfam06069
1133853002559	Integrase core domain; Region: rve; pfam00665
1133853002560	similar to polyketide synthase pksM (fragment); COG3321 Polyketide synthase modules and related proteins
1133853002561	similar to transposase (fragment), IS630 family protein; COG3335 Transposase and inactivated derivatives
1133853002562	similar to transposase (fragment), IS630 family protein; COG3335 Transposase and inactivated derivatives
1133853002563	similar to transposase (fragment), IS630 family protein; COG3415 Transposase and inactivated derivatives
1133853002564	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1133853002565	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1133853002566	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1133853002567	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1133853002568	Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462
1133853002569	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1133853002570	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133853002571	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133853002572	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133853002573	PAAR motif; Region: PAAR_motif; cl15808
1133853002574	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
1133853002575	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1133853002576	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1133853002577	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522; cl01406
1133853002578	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1133853002579	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1133853002580	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
1133853002581	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1133853002582	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853002583	Walker A motif; other site
1133853002584	ATP binding site [chemical binding]; other site
1133853002585	Walker B motif; other site
1133853002586	arginine finger; other site
1133853002587	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853002588	Walker A motif; other site
1133853002589	ATP binding site [chemical binding]; other site
1133853002590	Walker B motif; other site
1133853002591	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133853002592	similar to transposase ORF B (fragment), IS629; COG2801 Transposase and inactivated derivatives
1133853002593	Integrase core domain; Region: rve; pfam00665
1133853002594	Integrase core domain; Region: rve_3; cl15866
1133853002595	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1133853002596	ImpA domain protein; Region: DUF3702; pfam12486
1133853002597	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853002598	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853002599	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853002600	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853002601	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853002602	Integrase core domain; Region: rve; pfam00665
1133853002603	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853002604	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853002605	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853002606	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853002607	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853002608	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853002609	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853002610	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853002611	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853002612	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853002613	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853002614	Transposase; Region: HTH_Tnp_1; pfam01527
1133853002615	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853002616	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853002617	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1133853002618	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133853002619	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133853002620	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853002621	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853002622	Integrase core domain; Region: rve; pfam00665
1133853002623	Integrase core domain; Region: rve_3; cl15866
1133853002624	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133853002625	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133853002626	putative active site [active]
1133853002627	putative NTP binding site [chemical binding]; other site
1133853002628	putative nucleic acid binding site [nucleotide binding]; other site
1133853002629	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133853002630	putative transposase OrfB; Reviewed; Region: PHA02517
1133853002631	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1133853002632	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133853002633	Integrase core domain; Region: rve; pfam00665
1133853002634	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853002635	Transposase; Region: HTH_Tnp_1; pfam01527
1133853002636	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1133853002637	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133853002638	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1133853002639	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1133853002640	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133853002641	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133853002642	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
1133853002643	active site
1133853002644	catalytic triad [active]
1133853002645	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1133853002646	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853002647	Walker A motif; other site
1133853002648	ATP binding site [chemical binding]; other site
1133853002649	Walker B motif; other site
1133853002650	arginine finger; other site
1133853002651	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853002652	ATP binding site [chemical binding]; other site
1133853002653	putative Mg++ binding site [ion binding]; other site
1133853002654	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853002655	nucleotide binding region [chemical binding]; other site
1133853002656	ATP-binding site [chemical binding]; other site
1133853002657	SNF-7-like protein; Provisional; Region: PTZ00464
1133853002658	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
1133853002659	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853002660	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853002661	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853002662	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853002663	integrase; Provisional; Region: PRK09692
1133853002664	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853002665	active site
1133853002666	Int/Topo IB signature motif; other site
1133853002667	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1133853002668	ornithine decarboxylase; Provisional; Region: PRK13578
1133853002669	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133853002670	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133853002671	homodimer interface [polypeptide binding]; other site
1133853002672	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853002673	catalytic residue [active]
1133853002674	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133853002675	nucleoside transporter; Region: 2A0110; TIGR00889
1133853002676	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1133853002677	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1133853002678	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853002679	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853002680	catalytic residue [active]
1133853002681	oxidative damage protection protein; Provisional; Region: PRK05408
1133853002682	adenine DNA glycosylase; Provisional; Region: PRK10880
1133853002683	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1133853002684	minor groove reading motif; other site
1133853002685	helix-hairpin-helix signature motif; other site
1133853002686	substrate binding pocket [chemical binding]; other site
1133853002687	active site
1133853002688	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1133853002689	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1133853002690	DNA binding and oxoG recognition site [nucleotide binding]
1133853002691	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1133853002692	hypothetical protein; Provisional; Region: PRK11702
1133853002693	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853002694	hypothetical protein; Provisional; Region: PRK10626
1133853002695	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1133853002696	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1133853002697	homodimer interface [polypeptide binding]; other site
1133853002698	active site
1133853002699	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1133853002700	HemN family oxidoreductase; Provisional; Region: PRK05660
1133853002701	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853002702	FeS/SAM binding site; other site
1133853002703	HemN C-terminal domain; Region: HemN_C; pfam06969
1133853002704	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1133853002705	active site
1133853002706	dimerization interface [polypeptide binding]; other site
1133853002707	hypothetical protein; Validated; Region: PRK05090
1133853002708	YGGT family; Region: YGGT; pfam02325
1133853002709	YGGT family; Region: YGGT; pfam02325
1133853002710	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1133853002711	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133853002712	catalytic residue [active]
1133853002713	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1133853002714	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1133853002715	Walker A motif; other site
1133853002716	ATP binding site [chemical binding]; other site
1133853002717	Walker B motif; other site
1133853002718	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1133853002719	hypothetical protein; Validated; Region: PRK00228
1133853002720	glutathione synthetase; Provisional; Region: PRK05246
1133853002721	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1133853002722	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1133853002723	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1133853002724	RNA methyltransferase, RsmE family; Region: TIGR00046
1133853002725	DNA-specific endonuclease I; Provisional; Region: PRK15137
1133853002726	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1133853002727	hypothetical protein; Provisional; Region: PRK04860
1133853002728	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1133853002729	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1133853002730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853002731	putative substrate translocation pore; other site
1133853002732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853002733	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1133853002734	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1133853002735	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1133853002736	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1133853002737	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
1133853002738	Virulence promoting factor; Region: YqgB; pfam11036
1133853002739	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1133853002740	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1133853002741	dimer interface [polypeptide binding]; other site
1133853002742	active site
1133853002743	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133853002744	catalytic residues [active]
1133853002745	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1133853002746	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1133853002747	agmatinase; Region: agmatinase; TIGR01230
1133853002748	oligomer interface [polypeptide binding]; other site
1133853002749	putative active site [active]
1133853002750	Mn binding site [ion binding]; other site
1133853002751	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1133853002752	transketolase; Reviewed; Region: PRK12753
1133853002753	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1133853002754	TPP-binding site [chemical binding]; other site
1133853002755	dimer interface [polypeptide binding]; other site
1133853002756	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1133853002757	PYR/PP interface [polypeptide binding]; other site
1133853002758	dimer interface [polypeptide binding]; other site
1133853002759	TPP binding site [chemical binding]; other site
1133853002760	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1133853002761	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853002762	active site
1133853002763	phosphorylation site [posttranslational modification]
1133853002764	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1133853002765	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1133853002766	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1133853002767	active site
1133853002768	P-loop; other site
1133853002769	phosphorylation site [posttranslational modification]
1133853002770	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
1133853002771	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853002772	putative NAD(P) binding site [chemical binding]; other site
1133853002773	catalytic Zn binding site [ion binding]; other site
1133853002774	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1133853002775	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1133853002776	putative active site [active]
1133853002777	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1133853002778	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
1133853002779	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
1133853002780	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1133853002781	active site
1133853002782	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1133853002783	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1133853002784	Walker A/P-loop; other site
1133853002785	ATP binding site [chemical binding]; other site
1133853002786	Q-loop/lid; other site
1133853002787	ABC transporter signature motif; other site
1133853002788	Walker B; other site
1133853002789	D-loop; other site
1133853002790	H-loop/switch region; other site
1133853002791	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1133853002792	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1133853002793	Walker A/P-loop; other site
1133853002794	ATP binding site [chemical binding]; other site
1133853002795	Q-loop/lid; other site
1133853002796	ABC transporter signature motif; other site
1133853002797	Walker B; other site
1133853002798	D-loop; other site
1133853002799	H-loop/switch region; other site
1133853002800	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1133853002801	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1133853002802	trimer interface [polypeptide binding]; other site
1133853002803	putative Zn binding site [ion binding]; other site
1133853002804	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1133853002805	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1133853002806	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1133853002807	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1133853002808	Phosphoglycerate kinase; Region: PGK; pfam00162
1133853002809	substrate binding site [chemical binding]; other site
1133853002810	hinge regions; other site
1133853002811	ADP binding site [chemical binding]; other site
1133853002812	catalytic site [active]
1133853002813	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1133853002814	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1133853002815	active site
1133853002816	intersubunit interface [polypeptide binding]; other site
1133853002817	zinc binding site [ion binding]; other site
1133853002818	Na+ binding site [ion binding]; other site
1133853002819	mechanosensitive channel MscS; Provisional; Region: PRK10334
1133853002820	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133853002821	arginine exporter protein; Provisional; Region: PRK09304
1133853002822	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1133853002823	oxidative stress defense protein; Provisional; Region: PRK11087
1133853002824	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853002825	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853002826	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853002827	dimerization interface [polypeptide binding]; other site
1133853002828	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1133853002829	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
1133853002830	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1133853002831	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
1133853002832	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853002833	substrate binding site [chemical binding]; other site
1133853002834	oxyanion hole (OAH) forming residues; other site
1133853002835	trimer interface [polypeptide binding]; other site
1133853002836	membrane ATPase/protein kinase; Provisional; Region: PRK09435
1133853002837	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1133853002838	Walker A; other site
1133853002839	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
1133853002840	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1133853002841	B12 binding site [chemical binding]; other site
1133853002842	cobalt ligand [ion binding]; other site
1133853002843	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
1133853002844	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1133853002845	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853002846	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1133853002847	putative dimerization interface [polypeptide binding]; other site
1133853002848	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1133853002849	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133853002850	active site
1133853002851	dimer interface [polypeptide binding]; other site
1133853002852	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1133853002853	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1133853002854	ligand binding site [chemical binding]; other site
1133853002855	NAD binding site [chemical binding]; other site
1133853002856	tetramer interface [polypeptide binding]; other site
1133853002857	catalytic site [active]
1133853002858	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1133853002859	L-serine binding site [chemical binding]; other site
1133853002860	ACT domain interface; other site
1133853002861	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1133853002862	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1133853002863	Z-ring-associated protein; Provisional; Region: PRK10972
1133853002864	hypothetical protein; Reviewed; Region: PRK01736
1133853002865	proline aminopeptidase P II; Provisional; Region: PRK10879
1133853002866	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1133853002867	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1133853002868	active site
1133853002869	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1133853002870	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1133853002871	oxidoreductase; Provisional; Region: PRK08013
1133853002872	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1133853002873	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1133853002874	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1133853002875	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1133853002876	lipoyl attachment site [posttranslational modification]; other site
1133853002877	glycine dehydrogenase; Provisional; Region: PRK05367
1133853002878	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1133853002879	tetramer interface [polypeptide binding]; other site
1133853002880	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853002881	catalytic residue [active]
1133853002882	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1133853002883	tetramer interface [polypeptide binding]; other site
1133853002884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853002885	catalytic residue [active]
1133853002886	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
1133853002887	classical (c) SDRs; Region: SDR_c; cd05233
1133853002888	NAD(P) binding site [chemical binding]; other site
1133853002889	active site
1133853002890	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1133853002891	beta-galactosidase; Region: BGL; TIGR03356
1133853002892	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1133853002893	hemolysin; Provisional; Region: PRK15087
1133853002894	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1133853002895	putative global regulator; Reviewed; Region: PRK09559
1133853002896	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1133853002897	hypothetical protein; Provisional; Region: PRK10878
1133853002898	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1133853002899	flavodoxin FldB; Provisional; Region: PRK12359
1133853002900	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1133853002901	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1133853002902	active site
1133853002903	Int/Topo IB signature motif; other site
1133853002904	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1133853002905	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1133853002906	dimerization domain [polypeptide binding]; other site
1133853002907	dimer interface [polypeptide binding]; other site
1133853002908	catalytic residues [active]
1133853002909	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1133853002910	DHH family; Region: DHH; pfam01368
1133853002911	DHHA1 domain; Region: DHHA1; pfam02272
1133853002912	peptide chain release factor 2; Provisional; Region: PRK08787
1133853002913	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1133853002914	RF-1 domain; Region: RF-1; pfam00472
1133853002915	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1133853002916	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1133853002917	dimer interface [polypeptide binding]; other site
1133853002918	putative anticodon binding site; other site
1133853002919	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1133853002920	motif 1; other site
1133853002921	active site
1133853002922	motif 2; other site
1133853002923	motif 3; other site
1133853002924	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1133853002925	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1133853002926	active site
1133853002927	metal binding site [ion binding]; metal-binding site
1133853002928	nudix motif; other site
1133853002929	xanthine permease; Region: pbuX; TIGR03173
1133853002930	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
1133853002931	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853002932	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1133853002933	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853002934	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133853002935	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133853002936	guanine deaminase; Provisional; Region: PRK09228
1133853002937	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1133853002938	active site
1133853002939	uracil-xanthine permease; Region: ncs2; TIGR00801
1133853002940	putative hypoxanthine oxidase; Provisional; Region: PRK09800
1133853002941	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1133853002942	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1133853002943	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1133853002944	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
1133853002945	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1133853002946	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
1133853002947	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1133853002948	active site
1133853002949	putative substrate binding pocket [chemical binding]; other site
1133853002950	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
1133853002951	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1133853002952	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853002953	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853002954	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1133853002955	Ligand binding site; other site
1133853002956	metal-binding site
1133853002957	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1133853002958	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1133853002959	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1133853002960	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1133853002961	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
1133853002962	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1133853002963	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1133853002964	carbamate kinase; Reviewed; Region: PRK12686
1133853002965	putative substrate binding site [chemical binding]; other site
1133853002966	homodimer interface [polypeptide binding]; other site
1133853002967	nucleotide binding site [chemical binding]; other site
1133853002968	nucleotide binding site [chemical binding]; other site
1133853002969	D-hydantoinase; Region: D-hydantoinase; TIGR02033
1133853002970	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1133853002971	tetramer interface [polypeptide binding]; other site
1133853002972	active site
1133853002973	peptidase; Reviewed; Region: PRK13004
1133853002974	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
1133853002975	putative metal binding site [ion binding]; other site
1133853002976	putative dimer interface [polypeptide binding]; other site
1133853002977	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1133853002978	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1133853002979	catalytic residue [active]
1133853002980	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
1133853002981	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1133853002982	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1133853002983	GAF domain; Region: GAF; cl17456
1133853002984	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1133853002985	PAS domain; Region: PAS; smart00091
1133853002986	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853002987	Walker A motif; other site
1133853002988	ATP binding site [chemical binding]; other site
1133853002989	Walker B motif; other site
1133853002990	arginine finger; other site
1133853002991	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133853002992	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
1133853002993	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853002994	catalytic loop [active]
1133853002995	iron binding site [ion binding]; other site
1133853002996	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1133853002997	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
1133853002998	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1133853002999	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
1133853003000	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1133853003001	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1133853003002	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853003003	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133853003004	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1133853003005	potential frameshift: common BLAST hit: gi|170018890|ref|YP_001723844.1| surface presentation of antigens protein SpaO
1133853003006	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1133853003007	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1133853003008	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
1133853003009	potential frameshift: common BLAST hit: gi|209920314|ref|YP_002294398.1| putative type III secretion protein
1133853003010	type III secretion system protein SpaS; Validated; Region: PRK08156
1133853003011	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1133853003012	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853003013	DNA binding residues [nucleotide binding]
1133853003014	dimerization interface [polypeptide binding]; other site
1133853003015	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
1133853003016	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1133853003017	Type III secretion needle MxiH like; Region: MxiH; cl09641
1133853003018	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1133853003019	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
1133853003020	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
1133853003021	invasion protein OrgB; Provisional; Region: PRK15322
1133853003022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133853003023	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133853003024	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853003025	DNA binding residues [nucleotide binding]
1133853003026	dimerization interface [polypeptide binding]; other site
1133853003027	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1133853003028	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853003029	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853003030	catalytic residue [active]
1133853003031	transcriptional regulator; Provisional; Region: PRK11906
1133853003032	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1133853003033	DNA binding site [nucleotide binding]
1133853003034	Tetratricopeptide repeat; Region: TPR_2; pfam07719
1133853003035	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
1133853003036	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1133853003037	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1133853003038	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
1133853003039	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1133853003040	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1133853003041	DNA binding residues [nucleotide binding]
1133853003042	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133853003043	serine transporter; Region: stp; TIGR00814
1133853003044	putative acyltransferase; Provisional; Region: PRK05790
1133853003045	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133853003046	dimer interface [polypeptide binding]; other site
1133853003047	active site
1133853003048	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1133853003049	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1133853003050	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1133853003051	NADP binding site [chemical binding]; other site
1133853003052	homodimer interface [polypeptide binding]; other site
1133853003053	active site
1133853003054	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1133853003055	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003056	putative substrate translocation pore; other site
1133853003057	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003058	putative racemase; Provisional; Region: PRK10200
1133853003059	aspartate racemase; Region: asp_race; TIGR00035
1133853003060	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1133853003061	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853003062	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
1133853003063	putative dimerization interface [polypeptide binding]; other site
1133853003064	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1133853003065	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1133853003066	active site
1133853003067	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133853003068	substrate binding site [chemical binding]; other site
1133853003069	catalytic residues [active]
1133853003070	dimer interface [polypeptide binding]; other site
1133853003071	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1133853003072	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853003073	DNA binding site [nucleotide binding]
1133853003074	domain linker motif; other site
1133853003075	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1133853003076	dimerization interface (closed form) [polypeptide binding]; other site
1133853003077	ligand binding site [chemical binding]; other site
1133853003078	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1133853003079	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1133853003080	putative acyl-acceptor binding pocket; other site
1133853003081	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1133853003082	acyl-activating enzyme (AAE) consensus motif; other site
1133853003083	putative AMP binding site [chemical binding]; other site
1133853003084	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1133853003085	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003086	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853003087	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853003088	active site
1133853003089	catalytic tetrad [active]
1133853003090	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1133853003091	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1133853003092	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1133853003093	putative DNA-binding cleft [nucleotide binding]; other site
1133853003094	putative DNA clevage site; other site
1133853003095	molecular lever; other site
1133853003096	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1133853003097	putative active site [active]
1133853003098	Ap4A binding site [chemical binding]; other site
1133853003099	nudix motif; other site
1133853003100	putative metal binding site [ion binding]; other site
1133853003101	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1133853003102	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133853003103	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1133853003104	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133853003105	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133853003106	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
1133853003107	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1133853003108	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1133853003109	dimerization interface [polypeptide binding]; other site
1133853003110	active site
1133853003111	hypothetical protein; Provisional; Region: PRK10506
1133853003112	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1133853003113	hypothetical protein; Provisional; Region: PRK10557
1133853003114	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1133853003115	hypothetical protein; Provisional; Region: PRK11521
1133853003116	hypothetical protein; Provisional; Region: PRK10332
1133853003117	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1133853003118	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1133853003119	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
1133853003120	protease3; Provisional; Region: PRK15101
1133853003121	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1133853003122	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133853003123	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133853003124	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1133853003125	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1133853003126	AAA domain; Region: AAA_30; pfam13604
1133853003127	Family description; Region: UvrD_C_2; pfam13538
1133853003128	N-acetylglutamate synthase; Validated; Region: PRK05279
1133853003129	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1133853003130	putative feedback inhibition sensing region; other site
1133853003131	putative nucleotide binding site [chemical binding]; other site
1133853003132	putative substrate binding site [chemical binding]; other site
1133853003133	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853003134	Coenzyme A binding pocket [chemical binding]; other site
1133853003135	AMIN domain; Region: AMIN; pfam11741
1133853003136	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1133853003137	active site
1133853003138	metal binding site [ion binding]; metal-binding site
1133853003139	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1133853003140	MltA specific insert domain; Region: MltA; pfam03562
1133853003141	3D domain; Region: 3D; pfam06725
1133853003142	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1133853003143	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1133853003144	putative ATP binding site [chemical binding]; other site
1133853003145	putative substrate interface [chemical binding]; other site
1133853003146	CsdA-binding activator; Provisional; Region: PRK15019
1133853003147	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1133853003148	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1133853003149	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853003150	catalytic residue [active]
1133853003151	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1133853003152	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1133853003153	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853003154	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1133853003155	dimerization interface [polypeptide binding]; other site
1133853003156	substrate binding pocket [chemical binding]; other site
1133853003157	hypothetical protein; Provisional; Region: PRK10873
1133853003158	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1133853003159	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1133853003160	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1133853003161	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853003162	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853003163	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1133853003164	L-fuculokinase; Provisional; Region: PRK10331
1133853003165	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1133853003166	nucleotide binding site [chemical binding]; other site
1133853003167	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1133853003168	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1133853003169	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1133853003170	trimer interface [polypeptide binding]; other site
1133853003171	substrate binding site [chemical binding]; other site
1133853003172	Mn binding site [ion binding]; other site
1133853003173	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1133853003174	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003175	putative substrate translocation pore; other site
1133853003176	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133853003177	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1133853003178	intersubunit interface [polypeptide binding]; other site
1133853003179	active site
1133853003180	Zn2+ binding site [ion binding]; other site
1133853003181	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1133853003182	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1133853003183	dimer interface [polypeptide binding]; other site
1133853003184	active site
1133853003185	metal binding site [ion binding]; metal-binding site
1133853003186	flap endonuclease-like protein; Provisional; Region: PRK09482
1133853003187	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1133853003188	active site
1133853003189	metal binding site 1 [ion binding]; metal-binding site
1133853003190	putative 5' ssDNA interaction site; other site
1133853003191	metal binding site 3; metal-binding site
1133853003192	metal binding site 2 [ion binding]; metal-binding site
1133853003193	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1133853003194	putative DNA binding site [nucleotide binding]; other site
1133853003195	putative metal binding site [ion binding]; other site
1133853003196	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1133853003197	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1133853003198	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1133853003199	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133853003200	serine transporter; Region: stp; TIGR00814
1133853003201	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1133853003202	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1133853003203	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1133853003204	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1133853003205	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1133853003206	SecY interacting protein Syd; Provisional; Region: PRK04968
1133853003207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1133853003208	potential frameshift: common BLAST hit: gi|260869469|ref|YP_003235871.1| tRNA pseudouridine synthase
1133853003209	flavodoxin; Provisional; Region: PRK08105
1133853003210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003211	D-galactonate transporter; Region: 2A0114; TIGR00893
1133853003212	putative substrate translocation pore; other site
1133853003213	potential frameshift: common BLAST hit: gi|260845434|ref|YP_003223212.1| (D)-glucarate dehydratase 2 GudX
1133853003214	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1133853003215	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1133853003216	active site
1133853003217	tetramer interface [polypeptide binding]; other site
1133853003218	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1133853003219	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1133853003220	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853003221	dimerization interface [polypeptide binding]; other site
1133853003222	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853003223	dimer interface [polypeptide binding]; other site
1133853003224	phosphorylation site [posttranslational modification]
1133853003225	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853003226	ATP binding site [chemical binding]; other site
1133853003227	Mg2+ binding site [ion binding]; other site
1133853003228	G-X-G motif; other site
1133853003229	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1133853003230	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853003231	active site
1133853003232	phosphorylation site [posttranslational modification]
1133853003233	intermolecular recognition site; other site
1133853003234	dimerization interface [polypeptide binding]; other site
1133853003235	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133853003236	putative binding surface; other site
1133853003237	active site
1133853003238	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1133853003239	TRAM domain; Region: TRAM; pfam01938
1133853003240	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853003241	S-adenosylmethionine binding site [chemical binding]; other site
1133853003242	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1133853003243	HD domain; Region: HD_4; pfam13328
1133853003244	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1133853003245	synthetase active site [active]
1133853003246	NTP binding site [chemical binding]; other site
1133853003247	metal binding site [ion binding]; metal-binding site
1133853003248	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1133853003249	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1133853003250	antitoxin MazE; Provisional; Region: PRK09798
1133853003251	toxin MazF; Provisional; Region: PRK09907
1133853003252	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1133853003253	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1133853003254	homodimer interface [polypeptide binding]; other site
1133853003255	metal binding site [ion binding]; metal-binding site
1133853003256	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1133853003257	homodimer interface [polypeptide binding]; other site
1133853003258	active site
1133853003259	putative chemical substrate binding site [chemical binding]; other site
1133853003260	metal binding site [ion binding]; metal-binding site
1133853003261	CTP synthetase; Validated; Region: pyrG; PRK05380
1133853003262	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1133853003263	Catalytic site [active]
1133853003264	active site
1133853003265	UTP binding site [chemical binding]; other site
1133853003266	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1133853003267	active site
1133853003268	putative oxyanion hole; other site
1133853003269	catalytic triad [active]
1133853003270	enolase; Provisional; Region: eno; PRK00077
1133853003271	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1133853003272	dimer interface [polypeptide binding]; other site
1133853003273	metal binding site [ion binding]; metal-binding site
1133853003274	substrate binding pocket [chemical binding]; other site
1133853003275	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1133853003276	Repair protein; Region: Repair_PSII; pfam04536
1133853003277	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1133853003278	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1133853003279	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1133853003280	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1133853003281	nucleotide binding site [chemical binding]; other site
1133853003282	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853003283	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003284	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
1133853003285	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1133853003286	NADP binding site [chemical binding]; other site
1133853003287	homodimer interface [polypeptide binding]; other site
1133853003288	active site
1133853003289	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1133853003290	FAD binding domain; Region: FAD_binding_4; pfam01565
1133853003291	benzoate transport; Region: 2A0115; TIGR00895
1133853003292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003293	putative substrate translocation pore; other site
1133853003294	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1133853003295	Ligand binding site [chemical binding]; other site
1133853003296	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1133853003297	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1133853003298	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1133853003299	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1133853003300	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1133853003301	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
1133853003302	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1133853003303	putative oxidoreductase FixC; Provisional; Region: PRK10157
1133853003304	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
1133853003305	homohexamer interface [polypeptide binding]; other site
1133853003306	putative substrate stabilizing pore; other site
1133853003307	pterin binding site; other site
1133853003308	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1133853003309	Flavodoxin; Region: Flavodoxin_1; pfam00258
1133853003310	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1133853003311	FAD binding pocket [chemical binding]; other site
1133853003312	FAD binding motif [chemical binding]; other site
1133853003313	catalytic residues [active]
1133853003314	NAD binding pocket [chemical binding]; other site
1133853003315	phosphate binding motif [ion binding]; other site
1133853003316	beta-alpha-beta structure motif; other site
1133853003317	sulfite reductase subunit beta; Provisional; Region: PRK13504
1133853003318	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1133853003319	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1133853003320	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1133853003321	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133853003322	Active Sites [active]
1133853003323	Hok/gef family; Region: HOK_GEF; pfam01848
1133853003324	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853003325	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133853003326	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1133853003327	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1133853003328	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1133853003329	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1133853003330	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
1133853003331	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1133853003332	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1133853003333	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1133853003334	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
1133853003335	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1133853003336	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
1133853003337	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1133853003338	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1133853003339	metal binding site [ion binding]; metal-binding site
1133853003340	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1133853003341	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133853003342	Active Sites [active]
1133853003343	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1133853003344	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1133853003345	CysD dimerization site [polypeptide binding]; other site
1133853003346	G1 box; other site
1133853003347	putative GEF interaction site [polypeptide binding]; other site
1133853003348	GTP/Mg2+ binding site [chemical binding]; other site
1133853003349	Switch I region; other site
1133853003350	G2 box; other site
1133853003351	G3 box; other site
1133853003352	Switch II region; other site
1133853003353	G4 box; other site
1133853003354	G5 box; other site
1133853003355	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1133853003356	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1133853003357	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1133853003358	ligand-binding site [chemical binding]; other site
1133853003359	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1133853003360	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1133853003361	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1133853003362	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1133853003363	substrate binding site; other site
1133853003364	dimer interface; other site
1133853003365	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1133853003366	homotrimer interaction site [polypeptide binding]; other site
1133853003367	zinc binding site [ion binding]; other site
1133853003368	CDP-binding sites; other site
1133853003369	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1133853003370	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1133853003371	Permutation of conserved domain; other site
1133853003372	active site
1133853003373	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1133853003374	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1133853003375	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853003376	S-adenosylmethionine binding site [chemical binding]; other site
1133853003377	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1133853003378	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853003379	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133853003380	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1133853003381	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1133853003382	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133853003383	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1133853003384	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133853003385	DNA binding residues [nucleotide binding]
1133853003386	MarR family; Region: MarR_2; cl17246
1133853003387	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1133853003388	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1133853003389	Flavoprotein; Region: Flavoprotein; pfam02441
1133853003390	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1133853003391	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1133853003392	putative transporter; Provisional; Region: PRK09821
1133853003393	GntP family permease; Region: GntP_permease; pfam02447
1133853003394	hypothetical protein; Provisional; Region: PRK09989
1133853003395	putative aldolase; Validated; Region: PRK08130
1133853003396	active site
1133853003397	intersubunit interface [polypeptide binding]; other site
1133853003398	Zn2+ binding site [ion binding]; other site
1133853003399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1133853003400	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1133853003401	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1133853003402	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133853003403	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133853003404	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853003405	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1133853003406	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1133853003407	active site
1133853003408	metal binding site [ion binding]; metal-binding site
1133853003409	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1133853003410	MutS domain I; Region: MutS_I; pfam01624
1133853003411	MutS domain II; Region: MutS_II; pfam05188
1133853003412	MutS domain III; Region: MutS_III; pfam05192
1133853003413	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1133853003414	Walker A/P-loop; other site
1133853003415	ATP binding site [chemical binding]; other site
1133853003416	Q-loop/lid; other site
1133853003417	ABC transporter signature motif; other site
1133853003418	Walker B; other site
1133853003419	D-loop; other site
1133853003420	H-loop/switch region; other site
1133853003421	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1133853003422	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1133853003423	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133853003424	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133853003425	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853003426	Walker A motif; other site
1133853003427	ATP binding site [chemical binding]; other site
1133853003428	Walker B motif; other site
1133853003429	arginine finger; other site
1133853003430	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1133853003431	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1133853003432	dimerization interface [polypeptide binding]; other site
1133853003433	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1133853003434	ATP binding site [chemical binding]; other site
1133853003435	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1133853003436	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1133853003437	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1133853003438	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1133853003439	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1133853003440	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1133853003441	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1133853003442	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133853003443	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1133853003444	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853003445	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1133853003446	NADH dehydrogenase; Region: NADHdh; cl00469
1133853003447	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1133853003448	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1133853003449	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1133853003450	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1133853003451	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853003452	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1133853003453	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1133853003454	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1133853003455	nickel binding site [ion binding]; other site
1133853003456	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853003457	non-specific DNA binding site [nucleotide binding]; other site
1133853003458	salt bridge; other site
1133853003459	sequence-specific DNA binding site [nucleotide binding]; other site
1133853003460	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853003461	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853003462	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853003463	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1133853003464	beta-galactosidase; Region: BGL; TIGR03356
1133853003465	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1133853003466	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853003467	active site turn [active]
1133853003468	phosphorylation site [posttranslational modification]
1133853003469	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1133853003470	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133853003471	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853003472	DNA binding site [nucleotide binding]
1133853003473	domain linker motif; other site
1133853003474	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1133853003475	dimerization interface (closed form) [polypeptide binding]; other site
1133853003476	ligand binding site [chemical binding]; other site
1133853003477	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1133853003478	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1133853003479	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1133853003480	Acylphosphatase; Region: Acylphosphatase; pfam00708
1133853003481	HypF finger; Region: zf-HYPF; pfam07503
1133853003482	HypF finger; Region: zf-HYPF; pfam07503
1133853003483	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1133853003484	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1133853003485	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853003486	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1133853003487	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1133853003488	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1133853003489	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1133853003490	iron binding site [ion binding]; other site
1133853003491	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1133853003492	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133853003493	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853003494	Walker A motif; other site
1133853003495	ATP binding site [chemical binding]; other site
1133853003496	Walker B motif; other site
1133853003497	arginine finger; other site
1133853003498	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1133853003499	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1133853003500	putative active site [active]
1133853003501	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1133853003502	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1133853003503	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853003504	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853003505	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1133853003506	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1133853003507	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1133853003508	putative NAD(P) binding site [chemical binding]; other site
1133853003509	active site
1133853003510	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1133853003511	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1133853003512	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1133853003513	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1133853003514	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1133853003515	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1133853003516	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853003517	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853003518	hypothetical protein; Validated; Region: PRK03661
1133853003519	recombinase A; Provisional; Region: recA; PRK09354
1133853003520	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1133853003521	hexamer interface [polypeptide binding]; other site
1133853003522	Walker A motif; other site
1133853003523	ATP binding site [chemical binding]; other site
1133853003524	Walker B motif; other site
1133853003525	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1133853003526	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1133853003527	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1133853003528	motif 1; other site
1133853003529	active site
1133853003530	motif 2; other site
1133853003531	motif 3; other site
1133853003532	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1133853003533	DHHA1 domain; Region: DHHA1; pfam02272
1133853003534	carbon storage regulator; Provisional; Region: PRK01712
1133853003535	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1133853003536	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853003537	motif II; other site
1133853003538	Predicted membrane protein [Function unknown]; Region: COG1238
1133853003539	glutamate--cysteine ligase; Provisional; Region: PRK02107
1133853003540	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1133853003541	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1133853003542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003543	putative substrate translocation pore; other site
1133853003544	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003545	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1133853003546	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853003547	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853003548	transcriptional repressor MprA; Provisional; Region: PRK10870
1133853003549	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1133853003550	putative L-valine exporter; Provisional; Region: PRK10408
1133853003551	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1133853003552	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1133853003553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003554	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1133853003555	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1133853003556	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1133853003557	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853003558	dimer interface [polypeptide binding]; other site
1133853003559	conserved gate region; other site
1133853003560	putative PBP binding loops; other site
1133853003561	ABC-ATPase subunit interface; other site
1133853003562	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1133853003563	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1133853003564	Walker A/P-loop; other site
1133853003565	ATP binding site [chemical binding]; other site
1133853003566	Q-loop/lid; other site
1133853003567	ABC transporter signature motif; other site
1133853003568	Walker B; other site
1133853003569	D-loop; other site
1133853003570	H-loop/switch region; other site
1133853003571	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1133853003572	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1133853003573	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1133853003574	dimer interface [polypeptide binding]; other site
1133853003575	putative radical transfer pathway; other site
1133853003576	diiron center [ion binding]; other site
1133853003577	tyrosyl radical; other site
1133853003578	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1133853003579	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1133853003580	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1133853003581	active site
1133853003582	dimer interface [polypeptide binding]; other site
1133853003583	catalytic residues [active]
1133853003584	effector binding site; other site
1133853003585	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1133853003586	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1133853003587	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1133853003588	catalytic residues [active]
1133853003589	hypothetical protein; Provisional; Region: PRK10132
1133853003590	hypothetical protein; Provisional; Region: PRK10556
1133853003591	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1133853003592	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1133853003593	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1133853003594	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
1133853003595	active site residue [active]
1133853003596	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1133853003597	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853003598	dimerization interface [polypeptide binding]; other site
1133853003599	putative DNA binding site [nucleotide binding]; other site
1133853003600	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133853003601	putative Zn2+ binding site [ion binding]; other site
1133853003602	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1133853003603	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1133853003604	bacterial OsmY and nodulation domain; Region: BON; smart00749
1133853003605	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853003606	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1133853003607	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853003608	DNA-binding site [nucleotide binding]; DNA binding site
1133853003609	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853003610	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1133853003611	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
1133853003612	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853003613	inhibitor-cofactor binding pocket; inhibition site
1133853003614	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853003615	catalytic residue [active]
1133853003616	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1133853003617	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1133853003618	tetramerization interface [polypeptide binding]; other site
1133853003619	NAD(P) binding site [chemical binding]; other site
1133853003620	catalytic residues [active]
1133853003621	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1133853003622	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1133853003623	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1133853003624	substrate binding pocket [chemical binding]; other site
1133853003625	active site
1133853003626	iron coordination sites [ion binding]; other site
1133853003627	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
1133853003628	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1133853003629	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1133853003630	active site
1133853003631	catalytic site [active]
1133853003632	HTH-like domain; Region: HTH_21; pfam13276
1133853003633	Integrase core domain; Region: rve; pfam00665
1133853003634	DDE domain; Region: DDE_Tnp_IS240; pfam13610
1133853003635	Integrase core domain; Region: rve_3; pfam13683
1133853003636	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853003637	Transposase; Region: HTH_Tnp_1; cl17663
1133853003638	similar to GTP-binding factor (fragment) from CP4-like prophage; COG3596 Predicted GTPase
1133853003639	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133853003640	integrase; Provisional; Region: PRK09692
1133853003641	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853003642	active site
1133853003643	Int/Topo IB signature motif; other site
1133853003644	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1133853003645	SmpB-tmRNA interface; other site
1133853003646	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1133853003647	putative coenzyme Q binding site [chemical binding]; other site
1133853003648	hypothetical protein; Validated; Region: PRK01777
1133853003649	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1133853003650	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1133853003651	recombination and repair protein; Provisional; Region: PRK10869
1133853003652	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1133853003653	Walker A/P-loop; other site
1133853003654	ATP binding site [chemical binding]; other site
1133853003655	Q-loop/lid; other site
1133853003656	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1133853003657	Q-loop/lid; other site
1133853003658	ABC transporter signature motif; other site
1133853003659	Walker B; other site
1133853003660	D-loop; other site
1133853003661	H-loop/switch region; other site
1133853003662	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1133853003663	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1133853003664	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1133853003665	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1133853003666	dimer interface [polypeptide binding]; other site
1133853003667	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1133853003668	hypothetical protein; Provisional; Region: PRK11573
1133853003669	Domain of unknown function DUF21; Region: DUF21; pfam01595
1133853003670	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133853003671	Transporter associated domain; Region: CorC_HlyC; smart01091
1133853003672	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1133853003673	signal recognition particle protein; Provisional; Region: PRK10867
1133853003674	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1133853003675	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1133853003676	P loop; other site
1133853003677	GTP binding site [chemical binding]; other site
1133853003678	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1133853003679	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1133853003680	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1133853003681	RimM N-terminal domain; Region: RimM; pfam01782
1133853003682	PRC-barrel domain; Region: PRC; pfam05239
1133853003683	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1133853003684	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1133853003685	putative outer membrane lipoprotein; Provisional; Region: PRK09967
1133853003686	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133853003687	ligand binding site [chemical binding]; other site
1133853003688	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1133853003689	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853003690	metal binding site [ion binding]; metal-binding site
1133853003691	active site
1133853003692	I-site; other site
1133853003693	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1133853003694	lipoprotein; Provisional; Region: PRK11443
1133853003695	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
1133853003696	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1133853003697	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1133853003698	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1133853003699	Chorismate mutase type II; Region: CM_2; cl00693
1133853003700	prephenate dehydrogenase; Validated; Region: PRK08507
1133853003701	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1133853003702	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1133853003703	Prephenate dehydratase; Region: PDT; pfam00800
1133853003704	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1133853003705	putative L-Phe binding site [chemical binding]; other site
1133853003706	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1133853003707	30S subunit binding site; other site
1133853003708	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1133853003709	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1133853003710	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1133853003711	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853003712	RNA binding surface [nucleotide binding]; other site
1133853003713	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1133853003714	active site
1133853003715	hypothetical protein; Provisional; Region: PRK10723
1133853003716	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1133853003717	protein disaggregation chaperone; Provisional; Region: PRK10865
1133853003718	Clp amino terminal domain; Region: Clp_N; pfam02861
1133853003719	Clp amino terminal domain; Region: Clp_N; pfam02861
1133853003720	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853003721	Walker A motif; other site
1133853003722	ATP binding site [chemical binding]; other site
1133853003723	Walker B motif; other site
1133853003724	arginine finger; other site
1133853003725	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853003726	Walker A motif; other site
1133853003727	ATP binding site [chemical binding]; other site
1133853003728	Walker B motif; other site
1133853003729	arginine finger; other site
1133853003730	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1133853003731	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1133853003732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003733	putative substrate translocation pore; other site
1133853003734	lipoprotein; Provisional; Region: PRK10759
1133853003735	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1133853003736	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1133853003737	domain interface [polypeptide binding]; other site
1133853003738	putative active site [active]
1133853003739	catalytic site [active]
1133853003740	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1133853003741	domain interface [polypeptide binding]; other site
1133853003742	putative active site [active]
1133853003743	catalytic site [active]
1133853003744	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1133853003745	CoA binding domain; Region: CoA_binding_2; pfam13380
1133853003746	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1133853003747	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1133853003748	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1133853003749	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1133853003750	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1133853003751	thioredoxin 2; Provisional; Region: PRK10996
1133853003752	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1133853003753	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1133853003754	catalytic residues [active]
1133853003755	putative methyltransferase; Provisional; Region: PRK10864
1133853003756	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1133853003757	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1133853003758	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1133853003759	ligand binding site [chemical binding]; other site
1133853003760	active site
1133853003761	UGI interface [polypeptide binding]; other site
1133853003762	catalytic site [active]
1133853003763	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1133853003764	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1133853003765	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853003766	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853003767	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133853003768	dimerization interface [polypeptide binding]; other site
1133853003769	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853003770	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1133853003771	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133853003772	ATP binding site [chemical binding]; other site
1133853003773	Mg++ binding site [ion binding]; other site
1133853003774	motif III; other site
1133853003775	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853003776	nucleotide binding region [chemical binding]; other site
1133853003777	ATP-binding site [chemical binding]; other site
1133853003778	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1133853003779	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1133853003780	L-aspartate oxidase; Provisional; Region: PRK09077
1133853003781	L-aspartate oxidase; Provisional; Region: PRK06175
1133853003782	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1133853003783	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1133853003784	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133853003785	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133853003786	DNA binding residues [nucleotide binding]
1133853003787	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1133853003788	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1133853003789	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1133853003790	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1133853003791	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1133853003792	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1133853003793	GTP-binding protein LepA; Provisional; Region: PRK05433
1133853003794	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1133853003795	G1 box; other site
1133853003796	putative GEF interaction site [polypeptide binding]; other site
1133853003797	GTP/Mg2+ binding site [chemical binding]; other site
1133853003798	Switch I region; other site
1133853003799	G2 box; other site
1133853003800	G3 box; other site
1133853003801	Switch II region; other site
1133853003802	G4 box; other site
1133853003803	G5 box; other site
1133853003804	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1133853003805	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1133853003806	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1133853003807	signal peptidase I; Provisional; Region: PRK10861
1133853003808	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1133853003809	Catalytic site [active]
1133853003810	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1133853003811	ribonuclease III; Reviewed; Region: rnc; PRK00102
1133853003812	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1133853003813	dimerization interface [polypeptide binding]; other site
1133853003814	active site
1133853003815	metal binding site [ion binding]; metal-binding site
1133853003816	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1133853003817	dsRNA binding site [nucleotide binding]; other site
1133853003818	GTPase Era; Reviewed; Region: era; PRK00089
1133853003819	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1133853003820	G1 box; other site
1133853003821	GTP/Mg2+ binding site [chemical binding]; other site
1133853003822	Switch I region; other site
1133853003823	G2 box; other site
1133853003824	Switch II region; other site
1133853003825	G3 box; other site
1133853003826	G4 box; other site
1133853003827	G5 box; other site
1133853003828	KH domain; Region: KH_2; pfam07650
1133853003829	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1133853003830	Recombination protein O N terminal; Region: RecO_N; pfam11967
1133853003831	Recombination protein O C terminal; Region: RecO_C; pfam02565
1133853003832	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1133853003833	active site
1133853003834	hydrophilic channel; other site
1133853003835	dimerization interface [polypeptide binding]; other site
1133853003836	catalytic residues [active]
1133853003837	active site lid [active]
1133853003838	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
1133853003839	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1133853003840	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133853003841	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1133853003842	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133853003843	putative active site [active]
1133853003844	hypothetical protein; Provisional; Region: PRK11590
1133853003845	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1133853003846	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1133853003847	nucleoside/Zn binding site; other site
1133853003848	dimer interface [polypeptide binding]; other site
1133853003849	catalytic motif [active]
1133853003850	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1133853003851	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853003852	substrate binding pocket [chemical binding]; other site
1133853003853	membrane-bound complex binding site; other site
1133853003854	hinge residues; other site
1133853003855	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853003856	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853003857	catalytic residue [active]
1133853003858	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1133853003859	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1133853003860	dimerization interface [polypeptide binding]; other site
1133853003861	ATP binding site [chemical binding]; other site
1133853003862	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1133853003863	dimerization interface [polypeptide binding]; other site
1133853003864	ATP binding site [chemical binding]; other site
1133853003865	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1133853003866	putative active site [active]
1133853003867	catalytic triad [active]
1133853003868	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1133853003869	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853003870	dimer interface [polypeptide binding]; other site
1133853003871	phosphorylation site [posttranslational modification]
1133853003872	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853003873	ATP binding site [chemical binding]; other site
1133853003874	Mg2+ binding site [ion binding]; other site
1133853003875	G-X-G motif; other site
1133853003876	hypothetical protein; Provisional; Region: PRK10722
1133853003877	response regulator GlrR; Provisional; Region: PRK15115
1133853003878	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853003879	active site
1133853003880	phosphorylation site [posttranslational modification]
1133853003881	intermolecular recognition site; other site
1133853003882	dimerization interface [polypeptide binding]; other site
1133853003883	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853003884	Walker A motif; other site
1133853003885	ATP binding site [chemical binding]; other site
1133853003886	Walker B motif; other site
1133853003887	arginine finger; other site
1133853003888	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1133853003889	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1133853003890	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1133853003891	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1133853003892	heme-binding site [chemical binding]; other site
1133853003893	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1133853003894	FAD binding pocket [chemical binding]; other site
1133853003895	FAD binding motif [chemical binding]; other site
1133853003896	phosphate binding motif [ion binding]; other site
1133853003897	beta-alpha-beta structure motif; other site
1133853003898	NAD binding pocket [chemical binding]; other site
1133853003899	Heme binding  pocket [chemical binding]; other site
1133853003900	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1133853003901	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1133853003902	dimer interface [polypeptide binding]; other site
1133853003903	active site
1133853003904	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1133853003905	folate binding site [chemical binding]; other site
1133853003906	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1133853003907	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133853003908	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853003909	nucleotide binding site [chemical binding]; other site
1133853003910	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853003911	TPR motif; other site
1133853003912	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1133853003913	binding surface
1133853003914	TPR repeat; Region: TPR_11; pfam13414
1133853003915	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853003916	TPR motif; other site
1133853003917	binding surface
1133853003918	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1133853003919	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1133853003920	ligand binding site [chemical binding]; other site
1133853003921	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1133853003922	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853003923	Walker A/P-loop; other site
1133853003924	ATP binding site [chemical binding]; other site
1133853003925	Q-loop/lid; other site
1133853003926	ABC transporter signature motif; other site
1133853003927	Walker B; other site
1133853003928	D-loop; other site
1133853003929	H-loop/switch region; other site
1133853003930	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853003931	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853003932	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853003933	TM-ABC transporter signature motif; other site
1133853003934	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853003935	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
1133853003936	putative NAD(P) binding site [chemical binding]; other site
1133853003937	catalytic Zn binding site [ion binding]; other site
1133853003938	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
1133853003939	active site
1133853003940	catalytic residues [active]
1133853003941	Predicted membrane protein [Function unknown]; Region: COG2259
1133853003942	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
1133853003943	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853003944	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
1133853003945	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
1133853003946	NAD binding site [chemical binding]; other site
1133853003947	active site
1133853003948	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
1133853003949	[2Fe-2S] cluster binding site [ion binding]; other site
1133853003950	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
1133853003951	inter-subunit interface; other site
1133853003952	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1133853003953	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1133853003954	iron-sulfur cluster [ion binding]; other site
1133853003955	[2Fe-2S] cluster binding site [ion binding]; other site
1133853003956	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
1133853003957	beta subunit interface [polypeptide binding]; other site
1133853003958	alpha subunit interface [polypeptide binding]; other site
1133853003959	active site
1133853003960	substrate binding site [chemical binding]; other site
1133853003961	Fe binding site [ion binding]; other site
1133853003962	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1133853003963	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853003964	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
1133853003965	putative dimerization interface [polypeptide binding]; other site
1133853003966	putative substrate binding pocket [chemical binding]; other site
1133853003967	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1133853003968	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853003969	putative substrate translocation pore; other site
1133853003970	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1133853003971	PRD domain; Region: PRD; pfam00874
1133853003972	PRD domain; Region: PRD; pfam00874
1133853003973	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1133853003974	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1133853003975	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1133853003976	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1133853003977	active site
1133853003978	dimerization interface [polypeptide binding]; other site
1133853003979	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1133853003980	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1133853003981	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1133853003982	Rrf2 family protein; Region: rrf2_super; TIGR00738
1133853003983	cysteine desulfurase; Provisional; Region: PRK14012
1133853003984	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1133853003985	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853003986	catalytic residue [active]
1133853003987	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1133853003988	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1133853003989	trimerization site [polypeptide binding]; other site
1133853003990	active site
1133853003991	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1133853003992	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1133853003993	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133853003994	HSP70 interaction site [polypeptide binding]; other site
1133853003995	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1133853003996	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1133853003997	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1133853003998	nucleotide binding site [chemical binding]; other site
1133853003999	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1133853004000	SBD interface [polypeptide binding]; other site
1133853004001	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1133853004002	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853004003	catalytic loop [active]
1133853004004	iron binding site [ion binding]; other site
1133853004005	hypothetical protein; Provisional; Region: PRK10721
1133853004006	aminopeptidase B; Provisional; Region: PRK05015
1133853004007	Peptidase; Region: DUF3663; pfam12404
1133853004008	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1133853004009	interface (dimer of trimers) [polypeptide binding]; other site
1133853004010	Substrate-binding/catalytic site; other site
1133853004011	Zn-binding sites [ion binding]; other site
1133853004012	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1133853004013	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1133853004014	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1133853004015	active site residue [active]
1133853004016	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1133853004017	active site residue [active]
1133853004018	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1133853004019	MG2 domain; Region: A2M_N; pfam01835
1133853004020	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1133853004021	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1133853004022	surface patch; other site
1133853004023	thioester region; other site
1133853004024	specificity defining residues; other site
1133853004025	penicillin-binding protein 1C; Provisional; Region: PRK11240
1133853004026	Transglycosylase; Region: Transgly; pfam00912
1133853004027	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1133853004028	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1133853004029	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1133853004030	active site
1133853004031	multimer interface [polypeptide binding]; other site
1133853004032	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1133853004033	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853004034	FeS/SAM binding site; other site
1133853004035	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1133853004036	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853004037	non-specific DNA binding site [nucleotide binding]; other site
1133853004038	salt bridge; other site
1133853004039	sequence-specific DNA binding site [nucleotide binding]; other site
1133853004040	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1133853004041	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1133853004042	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1133853004043	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1133853004044	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1133853004045	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1133853004046	dimer interface [polypeptide binding]; other site
1133853004047	motif 1; other site
1133853004048	active site
1133853004049	motif 2; other site
1133853004050	motif 3; other site
1133853004051	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1133853004052	anticodon binding site; other site
1133853004053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1133853004054	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1133853004055	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
1133853004056	Trp docking motif [polypeptide binding]; other site
1133853004057	active site
1133853004058	GTP-binding protein Der; Reviewed; Region: PRK00093
1133853004059	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1133853004060	G1 box; other site
1133853004061	GTP/Mg2+ binding site [chemical binding]; other site
1133853004062	Switch I region; other site
1133853004063	G2 box; other site
1133853004064	Switch II region; other site
1133853004065	G3 box; other site
1133853004066	G4 box; other site
1133853004067	G5 box; other site
1133853004068	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1133853004069	G1 box; other site
1133853004070	GTP/Mg2+ binding site [chemical binding]; other site
1133853004071	Switch I region; other site
1133853004072	G2 box; other site
1133853004073	G3 box; other site
1133853004074	Switch II region; other site
1133853004075	G4 box; other site
1133853004076	G5 box; other site
1133853004077	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1133853004078	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1133853004079	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1133853004080	generic binding surface II; other site
1133853004081	generic binding surface I; other site
1133853004082	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1133853004083	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1133853004084	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1133853004085	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1133853004086	active site
1133853004087	GMP synthase; Reviewed; Region: guaA; PRK00074
1133853004088	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1133853004089	AMP/PPi binding site [chemical binding]; other site
1133853004090	candidate oxyanion hole; other site
1133853004091	catalytic triad [active]
1133853004092	potential glutamine specificity residues [chemical binding]; other site
1133853004093	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1133853004094	ATP Binding subdomain [chemical binding]; other site
1133853004095	Ligand Binding sites [chemical binding]; other site
1133853004096	Dimerization subdomain; other site
1133853004097	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1133853004098	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1133853004099	MASE1; Region: MASE1; pfam05231
1133853004100	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853004101	diguanylate cyclase; Region: GGDEF; smart00267
1133853004102	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853004103	exopolyphosphatase; Provisional; Region: PRK10854
1133853004104	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1133853004105	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1133853004106	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1133853004107	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1133853004108	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
1133853004109	domain interface [polypeptide binding]; other site
1133853004110	active site
1133853004111	catalytic site [active]
1133853004112	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1133853004113	putative active site [active]
1133853004114	catalytic site [active]
1133853004115	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1133853004116	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1133853004117	active site
1133853004118	substrate binding site [chemical binding]; other site
1133853004119	cosubstrate binding site; other site
1133853004120	catalytic site [active]
1133853004121	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1133853004122	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1133853004123	dimerization interface [polypeptide binding]; other site
1133853004124	putative ATP binding site [chemical binding]; other site
1133853004125	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853004126	active site
1133853004127	uracil transporter; Provisional; Region: PRK10720
1133853004128	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1133853004129	DNA replication initiation factor; Provisional; Region: PRK08084
1133853004130	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1133853004131	ArsC family; Region: ArsC; pfam03960
1133853004132	catalytic residues [active]
1133853004133	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1133853004134	Peptidase family M48; Region: Peptidase_M48; cl12018
1133853004135	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1133853004136	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1133853004137	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1133853004138	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
1133853004139	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133853004140	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853004141	Walker A motif; other site
1133853004142	ATP binding site [chemical binding]; other site
1133853004143	Walker B motif; other site
1133853004144	arginine finger; other site
1133853004145	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133853004146	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1133853004147	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1133853004148	hydrogenase 4 subunit H; Validated; Region: PRK08222
1133853004149	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853004150	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1133853004151	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1133853004152	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1133853004153	hydrogenase 4 subunit F; Validated; Region: PRK06458
1133853004154	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853004155	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
1133853004156	hydrogenase 4 subunit D; Validated; Region: PRK06525
1133853004157	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853004158	hydrogenase 4 subunit D; Validated; Region: PRK06525
1133853004159	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1133853004160	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1133853004161	NADH dehydrogenase; Region: NADHdh; cl00469
1133853004162	hydrogenase 4 subunit B; Validated; Region: PRK06521
1133853004163	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853004164	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133853004165	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853004166	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1133853004167	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1133853004168	catalytic triad [active]
1133853004169	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1133853004170	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1133853004171	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1133853004172	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1133853004173	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1133853004174	dimer interface [polypeptide binding]; other site
1133853004175	active site
1133853004176	catalytic residue [active]
1133853004177	lipoprotein; Provisional; Region: PRK11679
1133853004178	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1133853004179	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1133853004180	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1133853004181	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1133853004182	ATP binding site [chemical binding]; other site
1133853004183	active site
1133853004184	substrate binding site [chemical binding]; other site
1133853004185	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1133853004186	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1133853004187	oligomeric interface; other site
1133853004188	putative active site [active]
1133853004189	homodimer interface [polypeptide binding]; other site
1133853004190	Predicted metalloprotease [General function prediction only]; Region: COG2321
1133853004191	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1133853004192	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1133853004193	Helicase; Region: Helicase_RecD; pfam05127
1133853004194	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1133853004195	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1133853004196	putative hydrolase; Provisional; Region: PRK11460
1133853004197	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1133853004198	hypothetical protein; Provisional; Region: PRK13664
1133853004199	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1133853004200	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1133853004201	metal binding site [ion binding]; metal-binding site
1133853004202	dimer interface [polypeptide binding]; other site
1133853004203	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1133853004204	ArsC family; Region: ArsC; pfam03960
1133853004205	putative catalytic residues [active]
1133853004206	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1133853004207	Protein export membrane protein; Region: SecD_SecF; cl14618
1133853004208	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1133853004209	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1133853004210	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853004211	dimerization interface [polypeptide binding]; other site
1133853004212	Histidine kinase; Region: HisKA_3; pfam07730
1133853004213	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853004214	ATP binding site [chemical binding]; other site
1133853004215	Mg2+ binding site [ion binding]; other site
1133853004216	G-X-G motif; other site
1133853004217	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1133853004218	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853004219	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853004220	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853004221	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1133853004222	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1133853004223	dimer interface [polypeptide binding]; other site
1133853004224	ADP-ribose binding site [chemical binding]; other site
1133853004225	active site
1133853004226	nudix motif; other site
1133853004227	metal binding site [ion binding]; metal-binding site
1133853004228	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1133853004229	transketolase; Reviewed; Region: PRK12753
1133853004230	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1133853004231	TPP-binding site [chemical binding]; other site
1133853004232	dimer interface [polypeptide binding]; other site
1133853004233	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1133853004234	PYR/PP interface [polypeptide binding]; other site
1133853004235	dimer interface [polypeptide binding]; other site
1133853004236	TPP binding site [chemical binding]; other site
1133853004237	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1133853004238	transaldolase-like protein; Provisional; Region: PTZ00411
1133853004239	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1133853004240	active site
1133853004241	dimer interface [polypeptide binding]; other site
1133853004242	catalytic residue [active]
1133853004243	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1133853004244	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1133853004245	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1133853004246	putative NAD(P) binding site [chemical binding]; other site
1133853004247	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1133853004248	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1133853004249	putative hexamer interface [polypeptide binding]; other site
1133853004250	putative hexagonal pore; other site
1133853004251	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1133853004252	G1 box; other site
1133853004253	GTP/Mg2+ binding site [chemical binding]; other site
1133853004254	G2 box; other site
1133853004255	Switch I region; other site
1133853004256	G3 box; other site
1133853004257	Switch II region; other site
1133853004258	G4 box; other site
1133853004259	G5 box; other site
1133853004260	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1133853004261	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1133853004262	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1133853004263	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1133853004264	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1133853004265	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1133853004266	Hexamer interface [polypeptide binding]; other site
1133853004267	Putative hexagonal pore residue; other site
1133853004268	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1133853004269	Hexamer/Pentamer interface [polypeptide binding]; other site
1133853004270	central pore; other site
1133853004271	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1133853004272	putative catalytic cysteine [active]
1133853004273	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1133853004274	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853004275	nucleotide binding site [chemical binding]; other site
1133853004276	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1133853004277	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1133853004278	active site
1133853004279	metal binding site [ion binding]; metal-binding site
1133853004280	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1133853004281	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1133853004282	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1133853004283	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1133853004284	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1133853004285	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1133853004286	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1133853004287	putative hexamer interface [polypeptide binding]; other site
1133853004288	putative hexagonal pore; other site
1133853004289	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1133853004290	putative hexamer interface [polypeptide binding]; other site
1133853004291	putative hexagonal pore; other site
1133853004292	carboxysome structural protein EutK; Provisional; Region: PRK15466
1133853004293	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1133853004294	Hexamer interface [polypeptide binding]; other site
1133853004295	Hexagonal pore residue; other site
1133853004296	transcriptional regulator EutR; Provisional; Region: PRK10130
1133853004297	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853004298	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853004299	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1133853004300	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1133853004301	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1133853004302	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1133853004303	active site
1133853004304	metal binding site [ion binding]; metal-binding site
1133853004305	putative acetyltransferase; Provisional; Region: PRK03624
1133853004306	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853004307	Coenzyme A binding pocket [chemical binding]; other site
1133853004308	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1133853004309	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1133853004310	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1133853004311	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1133853004312	putative periplasmic esterase; Provisional; Region: PRK03642
1133853004313	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1133853004314	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1133853004315	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853004316	active site turn [active]
1133853004317	phosphorylation site [posttranslational modification]
1133853004318	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133853004319	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
1133853004320	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1133853004321	putative active site [active]
1133853004322	transcriptional regulator MurR; Provisional; Region: PRK15482
1133853004323	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133853004324	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133853004325	putative active site [active]
1133853004326	short chain dehydrogenase; Provisional; Region: PRK08226
1133853004327	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1133853004328	NAD binding site [chemical binding]; other site
1133853004329	homotetramer interface [polypeptide binding]; other site
1133853004330	homodimer interface [polypeptide binding]; other site
1133853004331	active site
1133853004332	thiosulfate transporter subunit; Provisional; Region: PRK10852
1133853004333	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1133853004334	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1133853004335	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853004336	dimer interface [polypeptide binding]; other site
1133853004337	conserved gate region; other site
1133853004338	putative PBP binding loops; other site
1133853004339	ABC-ATPase subunit interface; other site
1133853004340	sulfate transport protein; Provisional; Region: cysT; CHL00187
1133853004341	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853004342	dimer interface [polypeptide binding]; other site
1133853004343	conserved gate region; other site
1133853004344	putative PBP binding loops; other site
1133853004345	ABC-ATPase subunit interface; other site
1133853004346	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1133853004347	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1133853004348	Walker A/P-loop; other site
1133853004349	ATP binding site [chemical binding]; other site
1133853004350	Q-loop/lid; other site
1133853004351	ABC transporter signature motif; other site
1133853004352	Walker B; other site
1133853004353	D-loop; other site
1133853004354	H-loop/switch region; other site
1133853004355	TOBE-like domain; Region: TOBE_3; pfam12857
1133853004356	cysteine synthase B; Region: cysM; TIGR01138
1133853004357	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1133853004358	dimer interface [polypeptide binding]; other site
1133853004359	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853004360	catalytic residue [active]
1133853004361	hypothetical protein; Provisional; Region: PRK10318
1133853004362	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1133853004363	dimer interface [polypeptide binding]; other site
1133853004364	pyridoxamine kinase; Validated; Region: PRK05756
1133853004365	pyridoxal binding site [chemical binding]; other site
1133853004366	ATP binding site [chemical binding]; other site
1133853004367	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1133853004368	HPr interaction site; other site
1133853004369	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1133853004370	active site
1133853004371	phosphorylation site [posttranslational modification]
1133853004372	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1133853004373	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1133853004374	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133853004375	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133853004376	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133853004377	dimerization domain swap beta strand [polypeptide binding]; other site
1133853004378	regulatory protein interface [polypeptide binding]; other site
1133853004379	active site
1133853004380	regulatory phosphorylation site [posttranslational modification]; other site
1133853004381	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1133853004382	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1133853004383	dimer interface [polypeptide binding]; other site
1133853004384	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853004385	catalytic residue [active]
1133853004386	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1133853004387	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1133853004388	cell division protein ZipA; Provisional; Region: PRK03427
1133853004389	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1133853004390	FtsZ protein binding site [polypeptide binding]; other site
1133853004391	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1133853004392	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1133853004393	nucleotide binding pocket [chemical binding]; other site
1133853004394	K-X-D-G motif; other site
1133853004395	catalytic site [active]
1133853004396	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1133853004397	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1133853004398	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1133853004399	Dimer interface [polypeptide binding]; other site
1133853004400	BRCT sequence motif; other site
1133853004401	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1133853004402	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1133853004403	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1133853004404	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853004405	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853004406	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1133853004407	putative dimerization interface [polypeptide binding]; other site
1133853004408	hypothetical protein; Provisional; Region: PRK11528
1133853004409	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1133853004410	nucleoside transporter; Region: 2A0110; TIGR00889
1133853004411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853004412	putative substrate translocation pore; other site
1133853004413	XapX domain; Region: XapX; TIGR03510
1133853004414	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1133853004415	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853004416	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1133853004417	putative dimerization interface [polypeptide binding]; other site
1133853004418	putative substrate binding pocket [chemical binding]; other site
1133853004419	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1133853004420	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1133853004421	active site
1133853004422	HIGH motif; other site
1133853004423	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1133853004424	active site
1133853004425	KMSKS motif; other site
1133853004426	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853004427	salt bridge; other site
1133853004428	non-specific DNA binding site [nucleotide binding]; other site
1133853004429	sequence-specific DNA binding site [nucleotide binding]; other site
1133853004430	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1133853004431	MASE1; Region: MASE1; pfam05231
1133853004432	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853004433	diguanylate cyclase; Region: GGDEF; smart00267
1133853004434	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853004435	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1133853004436	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1133853004437	Nucleoside recognition; Region: Gate; pfam07670
1133853004438	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1133853004439	manganese transport protein MntH; Reviewed; Region: PRK00701
1133853004440	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1133853004441	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1133853004442	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1133853004443	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1133853004444	Cl- selectivity filter; other site
1133853004445	Cl- binding residues [ion binding]; other site
1133853004446	pore gating glutamate residue; other site
1133853004447	dimer interface [polypeptide binding]; other site
1133853004448	glucokinase, proteobacterial type; Region: glk; TIGR00749
1133853004449	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853004450	nucleotide binding site [chemical binding]; other site
1133853004451	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133853004452	active site
1133853004453	P-loop; other site
1133853004454	phosphorylation site [posttranslational modification]
1133853004455	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1133853004456	aminopeptidase; Provisional; Region: PRK09795
1133853004457	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1133853004458	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1133853004459	active site
1133853004460	exoaminopeptidase; Provisional; Region: PRK09961
1133853004461	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
1133853004462	oligomer interface [polypeptide binding]; other site
1133853004463	active site
1133853004464	metal binding site [ion binding]; metal-binding site
1133853004465	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133853004466	dimerization domain swap beta strand [polypeptide binding]; other site
1133853004467	regulatory protein interface [polypeptide binding]; other site
1133853004468	active site
1133853004469	regulatory phosphorylation site [posttranslational modification]; other site
1133853004470	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1133853004471	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1133853004472	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133853004473	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133853004474	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853004475	active site
1133853004476	phosphorylation site [posttranslational modification]
1133853004477	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853004478	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853004479	potential frameshift: common BLAST hit: gi|238900600|ref|YP_002926396.1| IS5 transposase and trans-activator
1133853004480	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1133853004481	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853004482	active site
1133853004483	phosphorylation site [posttranslational modification]
1133853004484	intermolecular recognition site; other site
1133853004485	dimerization interface [polypeptide binding]; other site
1133853004486	LytTr DNA-binding domain; Region: LytTR; pfam04397
1133853004487	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1133853004488	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1133853004489	GAF domain; Region: GAF; pfam01590
1133853004490	Histidine kinase; Region: His_kinase; pfam06580
1133853004491	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853004492	ATP binding site [chemical binding]; other site
1133853004493	Mg2+ binding site [ion binding]; other site
1133853004494	G-X-G motif; other site
1133853004495	aminotransferase; Validated; Region: PRK08175
1133853004496	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853004497	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853004498	homodimer interface [polypeptide binding]; other site
1133853004499	catalytic residue [active]
1133853004500	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1133853004501	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133853004502	putative acyl-acceptor binding pocket; other site
1133853004503	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1133853004504	hypothetical protein; Provisional; Region: PRK10316
1133853004505	YfdX protein; Region: YfdX; pfam10938
1133853004506	formyl-coenzyme A transferase; Provisional; Region: PRK05398
1133853004507	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1133853004508	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
1133853004509	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133853004510	PYR/PP interface [polypeptide binding]; other site
1133853004511	dimer interface [polypeptide binding]; other site
1133853004512	TPP binding site [chemical binding]; other site
1133853004513	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133853004514	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
1133853004515	TPP-binding site; other site
1133853004516	dimer interface [polypeptide binding]; other site
1133853004517	putative transporter YfdV; Provisional; Region: PRK09903
1133853004518	putative CoA-transferase; Provisional; Region: PRK11430
1133853004519	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1133853004520	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
1133853004521	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853004522	substrate binding pocket [chemical binding]; other site
1133853004523	membrane-bound complex binding site; other site
1133853004524	hinge residues; other site
1133853004525	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853004526	substrate binding pocket [chemical binding]; other site
1133853004527	membrane-bound complex binding site; other site
1133853004528	hinge residues; other site
1133853004529	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853004530	dimer interface [polypeptide binding]; other site
1133853004531	phosphorylation site [posttranslational modification]
1133853004532	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853004533	ATP binding site [chemical binding]; other site
1133853004534	Mg2+ binding site [ion binding]; other site
1133853004535	G-X-G motif; other site
1133853004536	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853004537	active site
1133853004538	phosphorylation site [posttranslational modification]
1133853004539	intermolecular recognition site; other site
1133853004540	dimerization interface [polypeptide binding]; other site
1133853004541	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133853004542	putative binding surface; other site
1133853004543	active site
1133853004544	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
1133853004545	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853004546	active site
1133853004547	phosphorylation site [posttranslational modification]
1133853004548	intermolecular recognition site; other site
1133853004549	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853004550	DNA binding residues [nucleotide binding]
1133853004551	dimerization interface [polypeptide binding]; other site
1133853004552	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1133853004553	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853004554	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853004555	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1133853004556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853004557	putative substrate translocation pore; other site
1133853004558	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853004559	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1133853004560	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1133853004561	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853004562	catalytic residue [active]
1133853004563	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1133853004564	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853004565	DNA binding site [nucleotide binding]
1133853004566	domain linker motif; other site
1133853004567	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1133853004568	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1133853004569	putative dimerization interface [polypeptide binding]; other site
1133853004570	putative ligand binding site [chemical binding]; other site
1133853004571	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1133853004572	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1133853004573	substrate binding [chemical binding]; other site
1133853004574	active site
1133853004575	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1133853004576	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853004577	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1133853004578	putative substrate binding site [chemical binding]; other site
1133853004579	putative ATP binding site [chemical binding]; other site
1133853004580	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1133853004581	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853004582	putative substrate translocation pore; other site
1133853004583	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1133853004584	hypothetical protein; Region: PHA00626
1133853004585	similar to prophage protein (fragment)
1133853004586	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853004587	Protein of unknown function (DUF2737); Region: DUF2737; pfam10930
1133853004588	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
1133853004589	ERF superfamily; Region: ERF; pfam04404
1133853004590	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
1133853004591	Lambda Phage CIII; Region: Lambda_CIII; pfam02061
1133853004592	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853004593	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853004594	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853004595	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853004596	Protein of unknown function (DUF2560); Region: DUF2560; pfam10834
1133853004597	Phage terminase large subunit; Region: Terminase_3; pfam04466
1133853004598	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
1133853004599	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
1133853004600	Phage stabilisation protein; Region: Phage_stabilise; pfam11134
1133853004601	Vitamin-D-receptor interacting Mediator subunit 4; Region: Med4; pfam10018
1133853004602	Protein of unknown function (DUF2824); Region: DUF2824; pfam11039
1133853004603	Arc-like DNA binding domain; Region: Arc; pfam03869
1133853004604	Prophage antirepressor [Transcription]; Region: COG3617
1133853004605	BRO family, N-terminal domain; Region: Bro-N; smart01040
1133853004606	Phage anti-repressor protein [Transcription]; Region: COG3561
1133853004607	Head binding; Region: Head_binding; pfam09008
1133853004608	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1133853004609	integrase; Provisional; Region: PRK09692
1133853004610	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853004611	active site
1133853004612	Int/Topo IB signature motif; other site
1133853004613	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1133853004614	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1133853004615	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1133853004616	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1133853004617	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1133853004618	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133853004619	dimer interface [polypeptide binding]; other site
1133853004620	active site
1133853004621	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1133853004622	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853004623	substrate binding site [chemical binding]; other site
1133853004624	oxyanion hole (OAH) forming residues; other site
1133853004625	trimer interface [polypeptide binding]; other site
1133853004626	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1133853004627	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133853004628	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133853004629	catalytic core [active]
1133853004630	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133853004631	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1133853004632	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853004633	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853004634	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853004635	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853004636	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853004637	Fimbrial protein; Region: Fimbrial; cl01416
1133853004638	Fimbrial protein; Region: Fimbrial; cl01416
1133853004639	Fimbrial protein; Region: Fimbrial; cl01416
1133853004640	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
1133853004641	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853004642	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853004643	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853004644	hypothetical protein; Provisional; Region: PRK04946
1133853004645	Smr domain; Region: Smr; pfam01713
1133853004646	HemK family putative methylases; Region: hemK_fam; TIGR00536
1133853004647	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853004648	S-adenosylmethionine binding site [chemical binding]; other site
1133853004649	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1133853004650	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1133853004651	Tetramer interface [polypeptide binding]; other site
1133853004652	active site
1133853004653	FMN-binding site [chemical binding]; other site
1133853004654	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1133853004655	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1133853004656	hypothetical protein; Provisional; Region: PRK10621
1133853004657	Predicted permeases [General function prediction only]; Region: COG0730
1133853004658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1133853004659	YfcL protein; Region: YfcL; pfam08891
1133853004660	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1133853004661	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1133853004662	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1133853004663	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1133853004664	dimer interface [polypeptide binding]; other site
1133853004665	active site
1133853004666	putative transporter; Provisional; Region: PRK12382
1133853004667	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853004668	putative substrate translocation pore; other site
1133853004669	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1133853004670	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1133853004671	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1133853004672	ligand binding site [chemical binding]; other site
1133853004673	NAD binding site [chemical binding]; other site
1133853004674	catalytic site [active]
1133853004675	homodimer interface [polypeptide binding]; other site
1133853004676	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1133853004677	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1133853004678	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1133853004679	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1133853004680	dimerization interface 3.5A [polypeptide binding]; other site
1133853004681	active site
1133853004682	hypothetical protein; Provisional; Region: PRK10847
1133853004683	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133853004684	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1133853004685	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1133853004686	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1133853004687	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133853004688	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133853004689	cell division protein DedD; Provisional; Region: PRK11633
1133853004690	Sporulation related domain; Region: SPOR; pfam05036
1133853004691	colicin V production protein; Provisional; Region: PRK10845
1133853004692	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1133853004693	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1133853004694	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1133853004695	active site
1133853004696	tetramer interface [polypeptide binding]; other site
1133853004697	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853004698	active site
1133853004699	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1133853004700	Flavoprotein; Region: Flavoprotein; pfam02441
1133853004701	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1133853004702	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853004703	substrate binding pocket [chemical binding]; other site
1133853004704	membrane-bound complex binding site; other site
1133853004705	hinge residues; other site
1133853004706	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1133853004707	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853004708	substrate binding pocket [chemical binding]; other site
1133853004709	membrane-bound complex binding site; other site
1133853004710	hinge residues; other site
1133853004711	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853004712	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853004713	dimer interface [polypeptide binding]; other site
1133853004714	conserved gate region; other site
1133853004715	putative PBP binding loops; other site
1133853004716	ABC-ATPase subunit interface; other site
1133853004717	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853004718	dimer interface [polypeptide binding]; other site
1133853004719	conserved gate region; other site
1133853004720	putative PBP binding loops; other site
1133853004721	ABC-ATPase subunit interface; other site
1133853004722	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1133853004723	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133853004724	Walker A/P-loop; other site
1133853004725	ATP binding site [chemical binding]; other site
1133853004726	Q-loop/lid; other site
1133853004727	ABC transporter signature motif; other site
1133853004728	Walker B; other site
1133853004729	D-loop; other site
1133853004730	H-loop/switch region; other site
1133853004731	putative transposase; Provisional; Region: PRK09857
1133853004732	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133853004733	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1133853004734	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1133853004735	putative NAD(P) binding site [chemical binding]; other site
1133853004736	putative active site [active]
1133853004737	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1133853004738	homooctamer interface [polypeptide binding]; other site
1133853004739	active site
1133853004740	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1133853004741	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1133853004742	C-terminal domain interface [polypeptide binding]; other site
1133853004743	GSH binding site (G-site) [chemical binding]; other site
1133853004744	dimer interface [polypeptide binding]; other site
1133853004745	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1133853004746	N-terminal domain interface [polypeptide binding]; other site
1133853004747	putative dimer interface [polypeptide binding]; other site
1133853004748	active site
1133853004749	glutathione S-transferase; Provisional; Region: PRK15113
1133853004750	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1133853004751	C-terminal domain interface [polypeptide binding]; other site
1133853004752	GSH binding site (G-site) [chemical binding]; other site
1133853004753	dimer interface [polypeptide binding]; other site
1133853004754	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1133853004755	N-terminal domain interface [polypeptide binding]; other site
1133853004756	putative dimer interface [polypeptide binding]; other site
1133853004757	putative substrate binding pocket (H-site) [chemical binding]; other site
1133853004758	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1133853004759	active site
1133853004760	metal binding site [ion binding]; metal-binding site
1133853004761	homotetramer interface [polypeptide binding]; other site
1133853004762	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1133853004763	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1133853004764	nudix motif; other site
1133853004765	hypothetical protein; Provisional; Region: PRK11588
1133853004766	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1133853004767	phosphate acetyltransferase; Reviewed; Region: PRK05632
1133853004768	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1133853004769	DRTGG domain; Region: DRTGG; pfam07085
1133853004770	phosphate acetyltransferase; Region: pta; TIGR00651
1133853004771	propionate/acetate kinase; Provisional; Region: PRK12379
1133853004772	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1133853004773	hypothetical protein; Provisional; Region: PRK01816
1133853004774	hypothetical protein; Validated; Region: PRK05445
1133853004775	putative phosphatase; Provisional; Region: PRK11587
1133853004776	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1133853004777	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853004778	motif II; other site
1133853004779	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1133853004780	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133853004781	TrkA-C domain; Region: TrkA_C; pfam02080
1133853004782	TrkA-C domain; Region: TrkA_C; pfam02080
1133853004783	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1133853004784	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133853004785	Zn2+ binding site [ion binding]; other site
1133853004786	Mg2+ binding site [ion binding]; other site
1133853004787	aminotransferase AlaT; Validated; Region: PRK09265
1133853004788	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853004789	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853004790	homodimer interface [polypeptide binding]; other site
1133853004791	catalytic residue [active]
1133853004792	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1133853004793	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853004794	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1133853004795	putative dimerization interface [polypeptide binding]; other site
1133853004796	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1133853004797	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1133853004798	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1133853004799	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1133853004800	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1133853004801	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1133853004802	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1133853004803	putative dimer interface [polypeptide binding]; other site
1133853004804	[2Fe-2S] cluster binding site [ion binding]; other site
1133853004805	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1133853004806	SLBB domain; Region: SLBB; pfam10531
1133853004807	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1133853004808	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1133853004809	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853004810	catalytic loop [active]
1133853004811	iron binding site [ion binding]; other site
1133853004812	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1133853004813	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1133853004814	[4Fe-4S] binding site [ion binding]; other site
1133853004815	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1133853004816	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1133853004817	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1133853004818	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853004819	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853004820	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1133853004821	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1133853004822	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1133853004823	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1133853004824	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853004825	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1133853004826	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853004827	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1133853004828	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133853004829	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
1133853004830	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1133853004831	potential frameshift: common BLAST hit: gi|218695872|ref|YP_002403539.1| deubiquitinase
1133853004832	ribonuclease BN; Region: true_RNase_BN; TIGR02649
1133853004833	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853004834	Coenzyme A binding pocket [chemical binding]; other site
1133853004835	hypothetical protein; Provisional; Region: PRK10404
1133853004836	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1133853004837	isochorismate synthases; Region: isochor_syn; TIGR00543
1133853004838	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1133853004839	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1133853004840	dimer interface [polypeptide binding]; other site
1133853004841	tetramer interface [polypeptide binding]; other site
1133853004842	PYR/PP interface [polypeptide binding]; other site
1133853004843	TPP binding site [chemical binding]; other site
1133853004844	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1133853004845	TPP-binding site; other site
1133853004846	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1133853004847	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1133853004848	catalytic site [active]
1133853004849	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853004850	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1133853004851	substrate binding site [chemical binding]; other site
1133853004852	oxyanion hole (OAH) forming residues; other site
1133853004853	trimer interface [polypeptide binding]; other site
1133853004854	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1133853004855	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1133853004856	active site
1133853004857	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1133853004858	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1133853004859	acyl-activating enzyme (AAE) consensus motif; other site
1133853004860	putative AMP binding site [chemical binding]; other site
1133853004861	putative active site [active]
1133853004862	putative CoA binding site [chemical binding]; other site
1133853004863	signal transduction protein PmrD; Provisional; Region: PRK15450
1133853004864	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1133853004865	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1133853004866	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1133853004867	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1133853004868	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1133853004869	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1133853004870	putative active site [active]
1133853004871	putative catalytic site [active]
1133853004872	putative Zn binding site [ion binding]; other site
1133853004873	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1133853004874	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
1133853004875	substrate binding site [chemical binding]; other site
1133853004876	cosubstrate binding site; other site
1133853004877	catalytic site [active]
1133853004878	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1133853004879	active site
1133853004880	hexamer interface [polypeptide binding]; other site
1133853004881	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1133853004882	NAD binding site [chemical binding]; other site
1133853004883	substrate binding site [chemical binding]; other site
1133853004884	active site
1133853004885	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1133853004886	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1133853004887	Ligand binding site; other site
1133853004888	Putative Catalytic site; other site
1133853004889	DXD motif; other site
1133853004890	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1133853004891	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1133853004892	inhibitor-cofactor binding pocket; inhibition site
1133853004893	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853004894	catalytic residue [active]
1133853004895	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1133853004896	catalytic core [active]
1133853004897	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1133853004898	YfaZ precursor; Region: YfaZ; pfam07437
1133853004899	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1133853004900	hypothetical protein; Provisional; Region: PRK03673
1133853004901	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1133853004902	putative MPT binding site; other site
1133853004903	Competence-damaged protein; Region: CinA; cl00666
1133853004904	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1133853004905	hypothetical protein; Provisional; Region: PRK09956
1133853004906	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133853004907	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1133853004908	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853004909	Cysteine-rich domain; Region: CCG; pfam02754
1133853004910	Cysteine-rich domain; Region: CCG; pfam02754
1133853004911	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1133853004912	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1133853004913	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1133853004914	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1133853004915	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1133853004916	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1133853004917	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853004918	putative substrate translocation pore; other site
1133853004919	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1133853004920	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1133853004921	active site
1133853004922	catalytic site [active]
1133853004923	metal binding site [ion binding]; metal-binding site
1133853004924	hypothetical protein; Provisional; Region: PRK09729
1133853004925	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853004926	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853004927	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853004928	hypothetical protein; Provisional; Region: PRK09902
1133853004929	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1133853004930	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853004931	catalytic loop [active]
1133853004932	iron binding site [ion binding]; other site
1133853004933	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1133853004934	dimer interface [polypeptide binding]; other site
1133853004935	putative radical transfer pathway; other site
1133853004936	diiron center [ion binding]; other site
1133853004937	tyrosyl radical; other site
1133853004938	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1133853004939	ATP cone domain; Region: ATP-cone; pfam03477
1133853004940	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1133853004941	active site
1133853004942	dimer interface [polypeptide binding]; other site
1133853004943	catalytic residues [active]
1133853004944	effector binding site; other site
1133853004945	R2 peptide binding site; other site
1133853004946	adhesin; Provisional; Region: PRK09752
1133853004947	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133853004948	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853004949	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1133853004950	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853004951	S-adenosylmethionine binding site [chemical binding]; other site
1133853004952	DNA gyrase subunit A; Validated; Region: PRK05560
1133853004953	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1133853004954	CAP-like domain; other site
1133853004955	active site
1133853004956	primary dimer interface [polypeptide binding]; other site
1133853004957	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853004958	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853004959	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853004960	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853004961	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853004962	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133853004963	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
1133853004964	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
1133853004965	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1133853004966	MG2 domain; Region: A2M_N; pfam01835
1133853004967	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1133853004968	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1133853004969	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
1133853004970	Predicted secreted protein [Function unknown]; Region: COG5445
1133853004971	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
1133853004972	Predicted secreted protein [Function unknown]; Region: COG5445
1133853004973	Stage II sporulation protein; Region: SpoIID; pfam08486
1133853004974	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
1133853004975	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
1133853004976	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
1133853004977	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1133853004978	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853004979	dimer interface [polypeptide binding]; other site
1133853004980	phosphorylation site [posttranslational modification]
1133853004981	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853004982	ATP binding site [chemical binding]; other site
1133853004983	Mg2+ binding site [ion binding]; other site
1133853004984	G-X-G motif; other site
1133853004985	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1133853004986	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853004987	active site
1133853004988	phosphorylation site [posttranslational modification]
1133853004989	intermolecular recognition site; other site
1133853004990	dimerization interface [polypeptide binding]; other site
1133853004991	transcriptional regulator RcsB; Provisional; Region: PRK10840
1133853004992	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853004993	active site
1133853004994	phosphorylation site [posttranslational modification]
1133853004995	intermolecular recognition site; other site
1133853004996	dimerization interface [polypeptide binding]; other site
1133853004997	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853004998	DNA binding residues [nucleotide binding]
1133853004999	dimerization interface [polypeptide binding]; other site
1133853005000	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1133853005001	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853005002	ATP binding site [chemical binding]; other site
1133853005003	G-X-G motif; other site
1133853005004	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133853005005	putative binding surface; other site
1133853005006	active site
1133853005007	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1133853005008	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133853005009	trimer interface [polypeptide binding]; other site
1133853005010	eyelet of channel; other site
1133853005011	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1133853005012	ApbE family; Region: ApbE; pfam02424
1133853005013	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1133853005014	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1133853005015	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853005016	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853005017	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1133853005018	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1133853005019	DNA binding site [nucleotide binding]
1133853005020	active site
1133853005021	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1133853005022	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1133853005023	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1133853005024	Walker A/P-loop; other site
1133853005025	ATP binding site [chemical binding]; other site
1133853005026	Q-loop/lid; other site
1133853005027	ABC transporter signature motif; other site
1133853005028	Walker B; other site
1133853005029	D-loop; other site
1133853005030	H-loop/switch region; other site
1133853005031	malate:quinone oxidoreductase; Validated; Region: PRK05257
1133853005032	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1133853005033	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1133853005034	secondary substrate binding site; other site
1133853005035	primary substrate binding site; other site
1133853005036	inhibition loop; other site
1133853005037	dimerization interface [polypeptide binding]; other site
1133853005038	tRNA synthetases class I (R); Region: tRNA-synt_1d; pfam00750
1133853005039	ferredoxin-type protein; Provisional; Region: PRK10194
1133853005040	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1133853005041	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1133853005042	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1133853005043	[4Fe-4S] binding site [ion binding]; other site
1133853005044	molybdopterin cofactor binding site; other site
1133853005045	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1133853005046	molybdopterin cofactor binding site; other site
1133853005047	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1133853005048	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1133853005049	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1133853005050	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1133853005051	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1133853005052	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1133853005053	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1133853005054	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1133853005055	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1133853005056	Walker A/P-loop; other site
1133853005057	ATP binding site [chemical binding]; other site
1133853005058	Q-loop/lid; other site
1133853005059	ABC transporter signature motif; other site
1133853005060	Walker B; other site
1133853005061	D-loop; other site
1133853005062	H-loop/switch region; other site
1133853005063	heme exporter protein CcmB; Region: ccmB; TIGR01190
1133853005064	heme exporter protein CcmC; Region: ccmC; TIGR01191
1133853005065	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1133853005066	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
1133853005067	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1133853005068	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1133853005069	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1133853005070	catalytic residues [active]
1133853005071	central insert; other site
1133853005072	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1133853005073	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1133853005074	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853005075	binding surface
1133853005076	TPR motif; other site
1133853005077	transcriptional regulator NarP; Provisional; Region: PRK10403
1133853005078	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853005079	active site
1133853005080	phosphorylation site [posttranslational modification]
1133853005081	intermolecular recognition site; other site
1133853005082	dimerization interface [polypeptide binding]; other site
1133853005083	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853005084	DNA binding residues [nucleotide binding]
1133853005085	dimerization interface [polypeptide binding]; other site
1133853005086	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133853005087	hypothetical protein; Provisional; Region: PRK09945
1133853005088	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133853005089	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853005090	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853005091	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853005092	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1133853005093	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1133853005094	Sulfatase; Region: Sulfatase; pfam00884
1133853005095	hypothetical protein; Provisional; Region: PRK13689
1133853005096	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1133853005097	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1133853005098	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1133853005099	5S rRNA interface [nucleotide binding]; other site
1133853005100	CTC domain interface [polypeptide binding]; other site
1133853005101	L16 interface [polypeptide binding]; other site
1133853005102	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133853005103	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853005104	ATP binding site [chemical binding]; other site
1133853005105	putative Mg++ binding site [ion binding]; other site
1133853005106	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853005107	nucleotide binding region [chemical binding]; other site
1133853005108	ATP-binding site [chemical binding]; other site
1133853005109	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1133853005110	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1133853005111	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853005112	RNA binding surface [nucleotide binding]; other site
1133853005113	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1133853005114	active site
1133853005115	uracil binding [chemical binding]; other site
1133853005116	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853005117	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1133853005118	putative substrate translocation pore; other site
1133853005119	hypothetical protein; Provisional; Region: PRK11835
1133853005120	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1133853005121	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853005122	Walker A/P-loop; other site
1133853005123	ATP binding site [chemical binding]; other site
1133853005124	Q-loop/lid; other site
1133853005125	ABC transporter signature motif; other site
1133853005126	Walker B; other site
1133853005127	D-loop; other site
1133853005128	H-loop/switch region; other site
1133853005129	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133853005130	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853005131	Walker A/P-loop; other site
1133853005132	ATP binding site [chemical binding]; other site
1133853005133	Q-loop/lid; other site
1133853005134	ABC transporter signature motif; other site
1133853005135	Walker B; other site
1133853005136	D-loop; other site
1133853005137	H-loop/switch region; other site
1133853005138	microcin C ABC transporter permease; Provisional; Region: PRK15021
1133853005139	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853005140	dimer interface [polypeptide binding]; other site
1133853005141	conserved gate region; other site
1133853005142	ABC-ATPase subunit interface; other site
1133853005143	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1133853005144	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853005145	dimer interface [polypeptide binding]; other site
1133853005146	conserved gate region; other site
1133853005147	putative PBP binding loops; other site
1133853005148	ABC-ATPase subunit interface; other site
1133853005149	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1133853005150	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1133853005151	phage resistance protein; Provisional; Region: PRK10551
1133853005152	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133853005153	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853005154	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1133853005155	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133853005156	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133853005157	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1133853005158	active site
1133853005159	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1133853005160	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1133853005161	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1133853005162	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1133853005163	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133853005164	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133853005165	elongation factor P; Provisional; Region: PRK04542
1133853005166	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1133853005167	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1133853005168	RNA binding site [nucleotide binding]; other site
1133853005169	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1133853005170	RNA binding site [nucleotide binding]; other site
1133853005171	Flagellin N-methylase; Region: FliB; pfam03692
1133853005172	sugar efflux transporter B; Provisional; Region: PRK15011
1133853005173	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853005174	putative substrate translocation pore; other site
1133853005175	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1133853005176	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853005177	active site
1133853005178	phosphorylation site [posttranslational modification]
1133853005179	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133853005180	dimerization domain swap beta strand [polypeptide binding]; other site
1133853005181	regulatory protein interface [polypeptide binding]; other site
1133853005182	active site
1133853005183	regulatory phosphorylation site [posttranslational modification]; other site
1133853005184	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1133853005185	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1133853005186	putative substrate binding site [chemical binding]; other site
1133853005187	putative ATP binding site [chemical binding]; other site
1133853005188	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1133853005189	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1133853005190	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133853005191	active site
1133853005192	P-loop; other site
1133853005193	phosphorylation site [posttranslational modification]
1133853005194	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1133853005195	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1133853005196	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853005197	substrate binding site [chemical binding]; other site
1133853005198	ATP binding site [chemical binding]; other site
1133853005199	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1133853005200	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1133853005201	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1133853005202	Nucleoside recognition; Region: Gate; pfam07670
1133853005203	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1133853005204	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
1133853005205	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1133853005206	ligand binding site [chemical binding]; other site
1133853005207	flexible hinge region; other site
1133853005208	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1133853005209	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1133853005210	active site
1133853005211	tetramer interface [polypeptide binding]; other site
1133853005212	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1133853005213	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1133853005214	Nucleoside recognition; Region: Gate; pfam07670
1133853005215	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1133853005216	putative kinase; Provisional; Region: PRK09954
1133853005217	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853005218	putative DNA binding site [nucleotide binding]; other site
1133853005219	putative Zn2+ binding site [ion binding]; other site
1133853005220	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1133853005221	substrate binding site [chemical binding]; other site
1133853005222	ATP binding site [chemical binding]; other site
1133853005223	endonuclease IV; Provisional; Region: PRK01060
1133853005224	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1133853005225	AP (apurinic/apyrimidinic) site pocket; other site
1133853005226	DNA interaction; other site
1133853005227	Metal-binding active site; metal-binding site
1133853005228	conserved hypothetical integral membrane protein; Region: TIGR00698
1133853005229	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1133853005230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853005231	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1133853005232	putative dimerization interface [polypeptide binding]; other site
1133853005233	lysine transporter; Provisional; Region: PRK10836
1133853005234	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1133853005235	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853005236	N-terminal plug; other site
1133853005237	ligand-binding site [chemical binding]; other site
1133853005238	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1133853005239	S-formylglutathione hydrolase; Region: PLN02442
1133853005240	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1133853005241	homodecamer interface [polypeptide binding]; other site
1133853005242	GTP cyclohydrolase I; Provisional; Region: PLN03044
1133853005243	active site
1133853005244	putative catalytic site residues [active]
1133853005245	zinc binding site [ion binding]; other site
1133853005246	GTP-CH-I/GFRP interaction surface; other site
1133853005247	Predicted membrane protein [Function unknown]; Region: COG2311
1133853005248	hypothetical protein; Provisional; Region: PRK10835
1133853005249	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1133853005250	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853005251	DNA binding site [nucleotide binding]
1133853005252	domain linker motif; other site
1133853005253	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1133853005254	dimerization interface (closed form) [polypeptide binding]; other site
1133853005255	ligand binding site [chemical binding]; other site
1133853005256	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1133853005257	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1133853005258	ligand binding site [chemical binding]; other site
1133853005259	calcium binding site [ion binding]; other site
1133853005260	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853005261	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1133853005262	Walker A/P-loop; other site
1133853005263	ATP binding site [chemical binding]; other site
1133853005264	Q-loop/lid; other site
1133853005265	ABC transporter signature motif; other site
1133853005266	Walker B; other site
1133853005267	D-loop; other site
1133853005268	H-loop/switch region; other site
1133853005269	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853005270	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853005271	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853005272	TM-ABC transporter signature motif; other site
1133853005273	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1133853005274	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1133853005275	homodimer interface [polypeptide binding]; other site
1133853005276	active site
1133853005277	FMN binding site [chemical binding]; other site
1133853005278	substrate binding site [chemical binding]; other site
1133853005279	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853005280	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1133853005281	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1133853005282	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853005283	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1133853005284	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133853005285	putative active site [active]
1133853005286	cytidine deaminase; Provisional; Region: PRK09027
1133853005287	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1133853005288	active site
1133853005289	catalytic motif [active]
1133853005290	Zn binding site [ion binding]; other site
1133853005291	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1133853005292	active site
1133853005293	catalytic motif [active]
1133853005294	Zn binding site [ion binding]; other site
1133853005295	hypothetical protein; Provisional; Region: PRK10711
1133853005296	hypothetical protein; Provisional; Region: PRK01821
1133853005297	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1133853005298	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1133853005299	FMN binding site [chemical binding]; other site
1133853005300	active site
1133853005301	catalytic residues [active]
1133853005302	substrate binding site [chemical binding]; other site
1133853005303	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1133853005304	oxidoreductase; Provisional; Region: PRK12743
1133853005305	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133853005306	NAD(P) binding site [chemical binding]; other site
1133853005307	active site
1133853005308	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133853005309	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1133853005310	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1133853005311	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1133853005312	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1133853005313	D-lactate dehydrogenase; Provisional; Region: PRK11183
1133853005314	FAD binding domain; Region: FAD_binding_4; pfam01565
1133853005315	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1133853005316	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1133853005317	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1133853005318	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1133853005319	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1133853005320	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853005321	dimer interface [polypeptide binding]; other site
1133853005322	conserved gate region; other site
1133853005323	ABC-ATPase subunit interface; other site
1133853005324	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1133853005325	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1133853005326	Walker A/P-loop; other site
1133853005327	ATP binding site [chemical binding]; other site
1133853005328	Q-loop/lid; other site
1133853005329	ABC transporter signature motif; other site
1133853005330	Walker B; other site
1133853005331	D-loop; other site
1133853005332	H-loop/switch region; other site
1133853005333	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1133853005334	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133853005335	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853005336	dimer interface [polypeptide binding]; other site
1133853005337	conserved gate region; other site
1133853005338	putative PBP binding loops; other site
1133853005339	ABC-ATPase subunit interface; other site
1133853005340	hypothetical protein; Provisional; Region: PRK13681
1133853005341	transcriptional regulator MirA; Provisional; Region: PRK15043
1133853005342	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1133853005343	DNA binding residues [nucleotide binding]
1133853005344	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1133853005345	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1133853005346	GAF domain; Region: GAF; pfam01590
1133853005347	Histidine kinase; Region: His_kinase; pfam06580
1133853005348	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853005349	ATP binding site [chemical binding]; other site
1133853005350	Mg2+ binding site [ion binding]; other site
1133853005351	G-X-G motif; other site
1133853005352	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1133853005353	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853005354	active site
1133853005355	phosphorylation site [posttranslational modification]
1133853005356	intermolecular recognition site; other site
1133853005357	dimerization interface [polypeptide binding]; other site
1133853005358	LytTr DNA-binding domain; Region: LytTR; pfam04397
1133853005359	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1133853005360	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1133853005361	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1133853005362	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1133853005363	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
1133853005364	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1133853005365	metal ion-dependent adhesion site (MIDAS); other site
1133853005366	MoxR-like ATPases [General function prediction only]; Region: COG0714
1133853005367	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853005368	Walker A motif; other site
1133853005369	ATP binding site [chemical binding]; other site
1133853005370	Walker B motif; other site
1133853005371	arginine finger; other site
1133853005372	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1133853005373	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
1133853005374	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1133853005375	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1133853005376	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1133853005377	active site
1133853005378	HIGH motif; other site
1133853005379	KMSKS motif; other site
1133853005380	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1133853005381	tRNA binding surface [nucleotide binding]; other site
1133853005382	anticodon binding site; other site
1133853005383	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1133853005384	dimer interface [polypeptide binding]; other site
1133853005385	putative tRNA-binding site [nucleotide binding]; other site
1133853005386	antiporter inner membrane protein; Provisional; Region: PRK11670
1133853005387	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1133853005388	Walker A motif; other site
1133853005389	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1133853005390	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133853005391	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
1133853005392	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853005393	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853005394	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1133853005395	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853005396	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853005397	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853005398	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1133853005399	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853005400	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853005401	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853005402	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1133853005403	Predicted integral membrane protein [Function unknown]; Region: COG5455
1133853005404	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1133853005405	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1133853005406	putative metal binding site [ion binding]; other site
1133853005407	putative homodimer interface [polypeptide binding]; other site
1133853005408	putative homotetramer interface [polypeptide binding]; other site
1133853005409	putative homodimer-homodimer interface [polypeptide binding]; other site
1133853005410	putative allosteric switch controlling residues; other site
1133853005411	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1133853005412	substrate binding site [chemical binding]; other site
1133853005413	multimerization interface [polypeptide binding]; other site
1133853005414	ATP binding site [chemical binding]; other site
1133853005415	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1133853005416	dimer interface [polypeptide binding]; other site
1133853005417	substrate binding site [chemical binding]; other site
1133853005418	ATP binding site [chemical binding]; other site
1133853005419	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
1133853005420	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
1133853005421	active site
1133853005422	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1133853005423	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853005424	DNA-binding site [nucleotide binding]; DNA binding site
1133853005425	UTRA domain; Region: UTRA; pfam07702
1133853005426	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853005427	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1133853005428	substrate binding site [chemical binding]; other site
1133853005429	ATP binding site [chemical binding]; other site
1133853005430	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1133853005431	nucleoside transporter; Region: 2A0110; TIGR00889
1133853005432	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853005433	putative substrate translocation pore; other site
1133853005434	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1133853005435	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1133853005436	putative active site; other site
1133853005437	catalytic residue [active]
1133853005438	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1133853005439	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1133853005440	intersubunit interface [polypeptide binding]; other site
1133853005441	active site
1133853005442	zinc binding site [ion binding]; other site
1133853005443	Na+ binding site [ion binding]; other site
1133853005444	potential frameshift: common BLAST hit: gi|291283341|ref|YP_003500159.1| tagatose 6-phosphate kinase
1133853005445	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853005446	active site
1133853005447	phosphorylation site [posttranslational modification]
1133853005448	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1133853005449	active site
1133853005450	P-loop; other site
1133853005451	phosphorylation site [posttranslational modification]
1133853005452	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1133853005453	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1133853005454	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1133853005455	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1133853005456	putative NAD(P) binding site [chemical binding]; other site
1133853005457	catalytic Zn binding site [ion binding]; other site
1133853005458	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133853005459	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133853005460	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853005461	lipid kinase; Reviewed; Region: PRK13054
1133853005462	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1133853005463	putative protease; Provisional; Region: PRK15452
1133853005464	Peptidase family U32; Region: Peptidase_U32; pfam01136
1133853005465	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1133853005466	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1133853005467	Uncharacterized conserved protein [Function unknown]; Region: COG3422
1133853005468	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1133853005469	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1133853005470	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853005471	active site
1133853005472	phosphorylation site [posttranslational modification]
1133853005473	intermolecular recognition site; other site
1133853005474	dimerization interface [polypeptide binding]; other site
1133853005475	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853005476	DNA binding site [nucleotide binding]
1133853005477	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1133853005478	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853005479	dimerization interface [polypeptide binding]; other site
1133853005480	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853005481	dimer interface [polypeptide binding]; other site
1133853005482	phosphorylation site [posttranslational modification]
1133853005483	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853005484	ATP binding site [chemical binding]; other site
1133853005485	Mg2+ binding site [ion binding]; other site
1133853005486	G-X-G motif; other site
1133853005487	putative transporter; Provisional; Region: PRK10504
1133853005488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853005489	putative substrate translocation pore; other site
1133853005490	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853005491	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1133853005492	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1133853005493	Protein export membrane protein; Region: SecD_SecF; cl14618
1133853005494	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1133853005495	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853005496	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853005497	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133853005498	metal ion-dependent adhesion site (MIDAS); other site
1133853005499	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1133853005500	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
1133853005501	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1133853005502	substrate binding site [chemical binding]; other site
1133853005503	activation loop (A-loop); other site
1133853005504	Y-family of DNA polymerases; Region: PolY; cl12025
1133853005505	putative chaperone; Provisional; Region: PRK11678
1133853005506	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1133853005507	nucleotide binding site [chemical binding]; other site
1133853005508	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1133853005509	SBD interface [polypeptide binding]; other site
1133853005510	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1133853005511	AlkA N-terminal domain; Region: AlkA_N; smart01009
1133853005512	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1133853005513	minor groove reading motif; other site
1133853005514	helix-hairpin-helix signature motif; other site
1133853005515	substrate binding pocket [chemical binding]; other site
1133853005516	active site
1133853005517	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1133853005518	putative diguanylate cyclase; Provisional; Region: PRK09776
1133853005519	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853005520	putative active site [active]
1133853005521	heme pocket [chemical binding]; other site
1133853005522	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853005523	putative active site [active]
1133853005524	heme pocket [chemical binding]; other site
1133853005525	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853005526	putative active site [active]
1133853005527	heme pocket [chemical binding]; other site
1133853005528	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853005529	metal binding site [ion binding]; metal-binding site
1133853005530	active site
1133853005531	I-site; other site
1133853005532	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1133853005533	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1133853005534	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1133853005535	ATP-binding site [chemical binding]; other site
1133853005536	Sugar specificity; other site
1133853005537	Pyrimidine base specificity; other site
1133853005538	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1133853005539	trimer interface [polypeptide binding]; other site
1133853005540	active site
1133853005541	putative assembly protein; Provisional; Region: PRK10833
1133853005542	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133853005543	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1133853005544	FOG: CBS domain [General function prediction only]; Region: COG0517
1133853005545	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133853005546	Transporter associated domain; Region: CorC_HlyC; smart01091
1133853005547	polysaccharide export protein Wza; Provisional; Region: PRK15078
1133853005548	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1133853005549	SLBB domain; Region: SLBB; pfam10531
1133853005550	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1133853005551	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1133853005552	active site
1133853005553	tyrosine kinase; Provisional; Region: PRK11519
1133853005554	Chain length determinant protein; Region: Wzz; pfam02706
1133853005555	Chain length determinant protein; Region: Wzz; cl15801
1133853005556	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133853005557	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1133853005558	putative glycosyl transferase; Provisional; Region: PRK10018
1133853005559	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1133853005560	active site
1133853005561	putative acyl transferase; Provisional; Region: PRK10191
1133853005562	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1133853005563	trimer interface [polypeptide binding]; other site
1133853005564	active site
1133853005565	substrate binding site [chemical binding]; other site
1133853005566	CoA binding site [chemical binding]; other site
1133853005567	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1133853005568	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1133853005569	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
1133853005570	putative glycosyl transferase; Provisional; Region: PRK10063
1133853005571	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1133853005572	metal-binding site
1133853005573	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1133853005574	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1133853005575	putative trimer interface [polypeptide binding]; other site
1133853005576	putative active site [active]
1133853005577	putative substrate binding site [chemical binding]; other site
1133853005578	putative CoA binding site [chemical binding]; other site
1133853005579	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1133853005580	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1133853005581	NADP-binding site; other site
1133853005582	homotetramer interface [polypeptide binding]; other site
1133853005583	substrate binding site [chemical binding]; other site
1133853005584	homodimer interface [polypeptide binding]; other site
1133853005585	active site
1133853005586	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1133853005587	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1133853005588	NADP binding site [chemical binding]; other site
1133853005589	active site
1133853005590	putative substrate binding site [chemical binding]; other site
1133853005591	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1133853005592	active site
1133853005593	GDP-Mannose binding site [chemical binding]; other site
1133853005594	dimer interface [polypeptide binding]; other site
1133853005595	modified nudix motif
1133853005596	metal binding site [ion binding]; metal-binding site
1133853005597	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1133853005598	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1133853005599	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1133853005600	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1133853005601	Substrate binding site; other site
1133853005602	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1133853005603	phosphomannomutase CpsG; Provisional; Region: PRK15414
1133853005604	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1133853005605	active site
1133853005606	substrate binding site [chemical binding]; other site
1133853005607	metal binding site [ion binding]; metal-binding site
1133853005608	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1133853005609	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1133853005610	colanic acid exporter; Provisional; Region: PRK10459
1133853005611	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1133853005612	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1133853005613	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
1133853005614	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
1133853005615	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1133853005616	putative ADP-binding pocket [chemical binding]; other site
1133853005617	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
1133853005618	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1133853005619	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133853005620	putative NAD(P) binding site [chemical binding]; other site
1133853005621	active site
1133853005622	putative substrate binding site [chemical binding]; other site
1133853005623	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1133853005624	active site
1133853005625	tetramer interface; other site
1133853005626	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1133853005627	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1133853005628	putative trimer interface [polypeptide binding]; other site
1133853005629	putative CoA binding site [chemical binding]; other site
1133853005630	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1133853005631	NeuB family; Region: NeuB; pfam03102
1133853005632	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1133853005633	NeuB binding interface [polypeptide binding]; other site
1133853005634	putative substrate binding site [chemical binding]; other site
1133853005635	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1133853005636	ligand binding site; other site
1133853005637	tetramer interface; other site
1133853005638	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
1133853005639	active site
1133853005640	catalytic triad [active]
1133853005641	oxyanion hole [active]
1133853005642	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1133853005643	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1133853005644	active site
1133853005645	homodimer interface [polypeptide binding]; other site
1133853005646	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
1133853005647	Predicted membrane protein [Function unknown]; Region: COG4485
1133853005648	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1133853005649	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1133853005650	putative ADP-binding pocket [chemical binding]; other site
1133853005651	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1133853005652	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1133853005653	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1133853005654	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1133853005655	active site
1133853005656	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1133853005657	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1133853005658	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1133853005659	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1133853005660	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1133853005661	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1133853005662	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1133853005663	chain length determinant protein WzzB; Provisional; Region: PRK15471
1133853005664	Chain length determinant protein; Region: Wzz; pfam02706
1133853005665	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1133853005666	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1133853005667	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1133853005668	metal binding site [ion binding]; metal-binding site
1133853005669	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1133853005670	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1133853005671	substrate binding site [chemical binding]; other site
1133853005672	glutamase interaction surface [polypeptide binding]; other site
1133853005673	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1133853005674	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1133853005675	catalytic residues [active]
1133853005676	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1133853005677	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1133853005678	putative active site [active]
1133853005679	oxyanion strand; other site
1133853005680	catalytic triad [active]
1133853005681	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1133853005682	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853005683	active site
1133853005684	motif I; other site
1133853005685	motif II; other site
1133853005686	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1133853005687	putative active site pocket [active]
1133853005688	4-fold oligomerization interface [polypeptide binding]; other site
1133853005689	metal binding residues [ion binding]; metal-binding site
1133853005690	3-fold/trimer interface [polypeptide binding]; other site
1133853005691	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1133853005692	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853005693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853005694	homodimer interface [polypeptide binding]; other site
1133853005695	catalytic residue [active]
1133853005696	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1133853005697	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1133853005698	NAD binding site [chemical binding]; other site
1133853005699	dimerization interface [polypeptide binding]; other site
1133853005700	product binding site; other site
1133853005701	substrate binding site [chemical binding]; other site
1133853005702	zinc binding site [ion binding]; other site
1133853005703	catalytic residues [active]
1133853005704	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1133853005705	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1133853005706	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1133853005707	antitoxin YefM; Provisional; Region: PRK11409
1133853005708	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
1133853005709	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133853005710	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1133853005711	putative NAD(P) binding site [chemical binding]; other site
1133853005712	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853005713	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1133853005714	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853005715	dimerization interface [polypeptide binding]; other site
1133853005716	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1133853005717	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1133853005718	Sulphur transport; Region: Sulf_transp; pfam04143
1133853005719	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1133853005720	CPxP  motif; other site
1133853005721	exonuclease I; Provisional; Region: sbcB; PRK11779
1133853005722	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1133853005723	active site
1133853005724	catalytic site [active]
1133853005725	substrate binding site [chemical binding]; other site
1133853005726	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1133853005727	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1133853005728	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1133853005729	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1133853005730	DNA gyrase inhibitor; Provisional; Region: PRK10016
1133853005731	Predicted membrane protein [Function unknown]; Region: COG1289
1133853005732	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133853005733	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853005734	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853005735	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853005736	hypothetical protein; Provisional; Region: PRK05423
1133853005737	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133853005738	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133853005739	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133853005740	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133853005741	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133853005742	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133853005743	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133853005744	MPN+ (JAMM) motif; other site
1133853005745	Zinc-binding site [ion binding]; other site
1133853005746	Antirestriction protein; Region: Antirestrict; pfam03230
1133853005747	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133853005748	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1133853005749	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1133853005750	nucleophile elbow; other site
1133853005751	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1133853005752	YjcZ-like protein; Region: YjcZ; pfam13990
1133853005753	hypothetical protein; Provisional; Region: PRK09866
1133853005754	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133853005755	G1 box; other site
1133853005756	GTP/Mg2+ binding site [chemical binding]; other site
1133853005757	G2 box; other site
1133853005758	Switch I region; other site
1133853005759	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133853005760	G3 box; other site
1133853005761	Switch II region; other site
1133853005762	GTP/Mg2+ binding site [chemical binding]; other site
1133853005763	G4 box; other site
1133853005764	G5 box; other site
1133853005765	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853005766	Transposase; Region: HTH_Tnp_1; pfam01527
1133853005767	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853005768	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853005769	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
1133853005770	homodimer interface [polypeptide binding]; other site
1133853005771	putative GKAP docking site [polypeptide binding]; other site
1133853005772	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853005773	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853005774	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853005775	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853005776	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853005777	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133853005778	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1133853005779	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133853005780	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853005781	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853005782	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133853005783	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133853005784	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133853005785	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133853005786	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
1133853005787	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
1133853005788	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1133853005789	active site
1133853005790	substrate binding pocket [chemical binding]; other site
1133853005791	homodimer interaction site [polypeptide binding]; other site
1133853005792	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1133853005793	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133853005794	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133853005795	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853005796	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1133853005797	substrate binding site [chemical binding]; other site
1133853005798	dimer interface [polypeptide binding]; other site
1133853005799	ATP binding site [chemical binding]; other site
1133853005800	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853005801	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1133853005802	homotrimer interface [polypeptide binding]; other site
1133853005803	Walker A motif; other site
1133853005804	GTP binding site [chemical binding]; other site
1133853005805	Walker B motif; other site
1133853005806	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
1133853005807	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1133853005808	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1133853005809	putative dimer interface [polypeptide binding]; other site
1133853005810	active site pocket [active]
1133853005811	putative cataytic base [active]
1133853005812	L,D-transpeptidase; Provisional; Region: PRK10190
1133853005813	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853005814	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1133853005815	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853005816	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1133853005817	putative dimerization interface [polypeptide binding]; other site
1133853005818	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1133853005819	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853005820	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
1133853005821	putative substrate binding site [chemical binding]; other site
1133853005822	dimerization interface [polypeptide binding]; other site
1133853005823	MATE family multidrug exporter; Provisional; Region: PRK10189
1133853005824	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1133853005825	hypothetical protein; Provisional; Region: PRK12378
1133853005826	AMP nucleosidase; Provisional; Region: PRK08292
1133853005827	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1133853005828	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1133853005829	shikimate transporter; Provisional; Region: PRK09952
1133853005830	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853005831	putative substrate translocation pore; other site
1133853005832	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1133853005833	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1133853005834	potential frameshift: common BLAST hit: gi|117624169|ref|YP_853082.1| autotransporter
1133853005835	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1133853005836	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1133853005837	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853005838	N-terminal plug; other site
1133853005839	ligand-binding site [chemical binding]; other site
1133853005840	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
1133853005841	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1133853005842	acyl-activating enzyme (AAE) consensus motif; other site
1133853005843	active site
1133853005844	AMP binding site [chemical binding]; other site
1133853005845	substrate binding site [chemical binding]; other site
1133853005846	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1133853005847	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
1133853005848	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133853005849	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1133853005850	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1133853005851	active site
1133853005852	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1133853005853	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1133853005854	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1133853005855	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
1133853005856	KR domain; Region: KR; pfam08659
1133853005857	NADP binding site [chemical binding]; other site
1133853005858	active site
1133853005859	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133853005860	Condensation domain; Region: Condensation; pfam00668
1133853005861	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1133853005862	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1133853005863	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1133853005864	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133853005865	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1133853005866	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1133853005867	Condensation domain; Region: Condensation; pfam00668
1133853005868	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1133853005869	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1133853005870	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
1133853005871	acyl-activating enzyme (AAE) consensus motif; other site
1133853005872	AMP binding site [chemical binding]; other site
1133853005873	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1133853005874	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853005875	S-adenosylmethionine binding site [chemical binding]; other site
1133853005876	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1133853005877	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133853005878	Condensation domain; Region: Condensation; pfam00668
1133853005879	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1133853005880	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1133853005881	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133853005882	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853005883	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853005884	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853005885	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1133853005886	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853005887	Walker A/P-loop; other site
1133853005888	ATP binding site [chemical binding]; other site
1133853005889	Q-loop/lid; other site
1133853005890	ABC transporter signature motif; other site
1133853005891	Walker B; other site
1133853005892	D-loop; other site
1133853005893	H-loop/switch region; other site
1133853005894	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1133853005895	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853005896	Walker A/P-loop; other site
1133853005897	ATP binding site [chemical binding]; other site
1133853005898	Q-loop/lid; other site
1133853005899	ABC transporter signature motif; other site
1133853005900	Walker B; other site
1133853005901	D-loop; other site
1133853005902	H-loop/switch region; other site
1133853005903	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
1133853005904	salicylate synthase Irp9; Reviewed; Region: PRK06772
1133853005905	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1133853005906	integrase; Provisional; Region: PRK09692
1133853005907	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853005908	active site
1133853005909	Int/Topo IB signature motif; other site
1133853005910	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1133853005911	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1133853005912	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1133853005913	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1133853005914	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1133853005915	Moco binding site; other site
1133853005916	metal coordination site [ion binding]; other site
1133853005917	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1133853005918	active site
1133853005919	homotetramer interface [polypeptide binding]; other site
1133853005920	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1133853005921	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853005922	active site
1133853005923	phosphorylation site [posttranslational modification]
1133853005924	intermolecular recognition site; other site
1133853005925	dimerization interface [polypeptide binding]; other site
1133853005926	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853005927	DNA binding site [nucleotide binding]
1133853005928	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1133853005929	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853005930	dimer interface [polypeptide binding]; other site
1133853005931	phosphorylation site [posttranslational modification]
1133853005932	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853005933	ATP binding site [chemical binding]; other site
1133853005934	Mg2+ binding site [ion binding]; other site
1133853005935	G-X-G motif; other site
1133853005936	chaperone protein HchA; Provisional; Region: PRK04155
1133853005937	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
1133853005938	dimer interface [polypeptide binding]; other site
1133853005939	metal binding site [ion binding]; metal-binding site
1133853005940	potential oxyanion hole; other site
1133853005941	potential catalytic triad [active]
1133853005942	conserved cys residue [active]
1133853005943	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853005944	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853005945	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853005946	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853005947	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133853005948	Integrase core domain; Region: rve; pfam00665
1133853005949	Integrase core domain; Region: rve_3; pfam13683
1133853005950	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1133853005951	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133853005952	Integrase core domain; Region: rve; pfam00665
1133853005953	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853005954	Transposase; Region: HTH_Tnp_1; pfam01527
1133853005955	potential frameshift: common BLAST hit: gi|117624102|ref|YP_853015.1| Outer membrane protein N precursor
1133853005956	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1133853005957	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1133853005958	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133853005959	Zn2+ binding site [ion binding]; other site
1133853005960	Mg2+ binding site [ion binding]; other site
1133853005961	DNA cytosine methylase; Provisional; Region: PRK10458
1133853005962	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1133853005963	cofactor binding site; other site
1133853005964	DNA binding site [nucleotide binding]
1133853005965	substrate interaction site [chemical binding]; other site
1133853005966	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1133853005967	additional DNA contacts [nucleotide binding]; other site
1133853005968	mismatch recognition site; other site
1133853005969	active site
1133853005970	zinc binding site [ion binding]; other site
1133853005971	DNA intercalation site [nucleotide binding]; other site
1133853005972	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1133853005973	EamA-like transporter family; Region: EamA; pfam00892
1133853005974	hypothetical protein; Provisional; Region: PRK10062
1133853005975	Uncharacterized small protein [Function unknown]; Region: COG5475
1133853005976	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1133853005977	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1133853005978	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853005979	metal binding site [ion binding]; metal-binding site
1133853005980	active site
1133853005981	I-site; other site
1133853005982	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1133853005983	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853005984	active site
1133853005985	motif I; other site
1133853005986	motif II; other site
1133853005987	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1133853005988	hypothetical protein; Provisional; Region: PRK10708
1133853005989	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1133853005990	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853005991	DNA binding residues [nucleotide binding]
1133853005992	dimerization interface [polypeptide binding]; other site
1133853005993	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1133853005994	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1133853005995	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1133853005996	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1133853005997	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1133853005998	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1133853005999	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1133853006000	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1133853006001	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1133853006002	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1133853006003	flagellar hook-length control protein; Provisional; Region: PRK10118
1133853006004	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1133853006005	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1133853006006	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1133853006007	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1133853006008	Walker A motif/ATP binding site; other site
1133853006009	Walker B motif; other site
1133853006010	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1133853006011	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1133853006012	Flagellar assembly protein FliH; Region: FliH; pfam02108
1133853006013	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1133853006014	FliG C-terminal domain; Region: FliG_C; pfam01706
1133853006015	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
1133853006016	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1133853006017	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1133853006018	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1133853006019	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
1133853006020	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1133853006021	substrate binding site [chemical binding]; other site
1133853006022	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853006023	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
1133853006024	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
1133853006025	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1133853006026	CPxP  motif; other site
1133853006027	putative inner membrane protein; Provisional; Region: PRK11099
1133853006028	lipoprotein; Provisional; Region: PRK10397
1133853006029	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1133853006030	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1133853006031	active site
1133853006032	Na/Ca binding site [ion binding]; other site
1133853006033	catalytic site [active]
1133853006034	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1133853006035	Flagellar protein FliS; Region: FliS; cl00654
1133853006036	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1133853006037	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1133853006038	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1133853006039	flagellin; Validated; Region: PRK06819
1133853006040	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1133853006041	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1133853006042	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1133853006043	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133853006044	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1133853006045	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133853006046	DNA binding residues [nucleotide binding]
1133853006047	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1133853006048	cystine transporter subunit; Provisional; Region: PRK11260
1133853006049	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853006050	substrate binding pocket [chemical binding]; other site
1133853006051	membrane-bound complex binding site; other site
1133853006052	hinge residues; other site
1133853006053	D-cysteine desulfhydrase; Validated; Region: PRK03910
1133853006054	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1133853006055	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853006056	catalytic residue [active]
1133853006057	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853006058	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853006059	dimer interface [polypeptide binding]; other site
1133853006060	conserved gate region; other site
1133853006061	putative PBP binding loops; other site
1133853006062	ABC-ATPase subunit interface; other site
1133853006063	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1133853006064	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133853006065	Walker A/P-loop; other site
1133853006066	ATP binding site [chemical binding]; other site
1133853006067	Q-loop/lid; other site
1133853006068	ABC transporter signature motif; other site
1133853006069	Walker B; other site
1133853006070	D-loop; other site
1133853006071	H-loop/switch region; other site
1133853006072	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1133853006073	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1133853006074	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853006075	DNA binding residues [nucleotide binding]
1133853006076	dimerization interface [polypeptide binding]; other site
1133853006077	hypothetical protein; Provisional; Region: PRK10613
1133853006078	response regulator; Provisional; Region: PRK09483
1133853006079	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853006080	active site
1133853006081	phosphorylation site [posttranslational modification]
1133853006082	intermolecular recognition site; other site
1133853006083	dimerization interface [polypeptide binding]; other site
1133853006084	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853006085	DNA binding residues [nucleotide binding]
1133853006086	dimerization interface [polypeptide binding]; other site
1133853006087	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1133853006088	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1133853006089	GIY-YIG motif/motif A; other site
1133853006090	active site
1133853006091	catalytic site [active]
1133853006092	putative DNA binding site [nucleotide binding]; other site
1133853006093	metal binding site [ion binding]; metal-binding site
1133853006094	UvrB/uvrC motif; Region: UVR; pfam02151
1133853006095	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1133853006096	Helix-hairpin-helix motif; Region: HHH; pfam00633
1133853006097	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1133853006098	hypothetical protein; Provisional; Region: PRK10396
1133853006099	yecA family protein; Region: ygfB_yecA; TIGR02292
1133853006100	SEC-C motif; Region: SEC-C; pfam02810
1133853006101	tyrosine transporter TyrP; Provisional; Region: PRK15132
1133853006102	aromatic amino acid transport protein; Region: araaP; TIGR00837
1133853006103	probable metal-binding protein; Region: matur_matur; TIGR03853
1133853006104	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1133853006105	Ferritin-like domain; Region: Ferritin; pfam00210
1133853006106	ferroxidase diiron center [ion binding]; other site
1133853006107	YecR-like lipoprotein; Region: YecR; pfam13992
1133853006108	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
1133853006109	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1133853006110	Ferritin-like domain; Region: Ferritin; pfam00210
1133853006111	ferroxidase diiron center [ion binding]; other site
1133853006112	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1133853006113	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1133853006114	ligand binding site [chemical binding]; other site
1133853006115	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1133853006116	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853006117	Walker A/P-loop; other site
1133853006118	ATP binding site [chemical binding]; other site
1133853006119	Q-loop/lid; other site
1133853006120	ABC transporter signature motif; other site
1133853006121	Walker B; other site
1133853006122	D-loop; other site
1133853006123	H-loop/switch region; other site
1133853006124	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853006125	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853006126	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853006127	TM-ABC transporter signature motif; other site
1133853006128	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1133853006129	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1133853006130	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1133853006131	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1133853006132	active site
1133853006133	homotetramer interface [polypeptide binding]; other site
1133853006134	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853006135	Ligand Binding Site [chemical binding]; other site
1133853006136	transcriptional activator FlhD; Provisional; Region: PRK02909
1133853006137	transcriptional activator FlhC; Provisional; Region: PRK12722
1133853006138	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1133853006139	flagellar motor protein MotA; Validated; Region: PRK09110
1133853006140	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1133853006141	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1133853006142	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133853006143	ligand binding site [chemical binding]; other site
1133853006144	chemotaxis protein CheA; Provisional; Region: PRK10547
1133853006145	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133853006146	putative binding surface; other site
1133853006147	active site
1133853006148	CheY binding; Region: CheY-binding; pfam09078
1133853006149	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1133853006150	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853006151	ATP binding site [chemical binding]; other site
1133853006152	Mg2+ binding site [ion binding]; other site
1133853006153	G-X-G motif; other site
1133853006154	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1133853006155	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1133853006156	putative CheA interaction surface; other site
1133853006157	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1133853006158	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133853006159	dimer interface [polypeptide binding]; other site
1133853006160	ligand binding site [chemical binding]; other site
1133853006161	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853006162	dimerization interface [polypeptide binding]; other site
1133853006163	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133853006164	dimer interface [polypeptide binding]; other site
1133853006165	putative CheW interface [polypeptide binding]; other site
1133853006166	methyl-accepting protein IV; Provisional; Region: PRK09793
1133853006167	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133853006168	dimer interface [polypeptide binding]; other site
1133853006169	ligand binding site [chemical binding]; other site
1133853006170	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853006171	dimerization interface [polypeptide binding]; other site
1133853006172	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133853006173	dimer interface [polypeptide binding]; other site
1133853006174	putative CheW interface [polypeptide binding]; other site
1133853006175	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1133853006176	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1133853006177	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853006178	S-adenosylmethionine binding site [chemical binding]; other site
1133853006179	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1133853006180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853006181	active site
1133853006182	phosphorylation site [posttranslational modification]
1133853006183	intermolecular recognition site; other site
1133853006184	dimerization interface [polypeptide binding]; other site
1133853006185	CheB methylesterase; Region: CheB_methylest; pfam01339
1133853006186	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1133853006187	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853006188	active site
1133853006189	phosphorylation site [posttranslational modification]
1133853006190	intermolecular recognition site; other site
1133853006191	dimerization interface [polypeptide binding]; other site
1133853006192	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1133853006193	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1133853006194	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1133853006195	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1133853006196	FHIPEP family; Region: FHIPEP; pfam00771
1133853006197	Flagellar protein FlhE; Region: FlhE; pfam06366
1133853006198	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1133853006199	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1133853006200	arginyl-tRNA synthetase; Region: argS; TIGR00456
1133853006201	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1133853006202	active site
1133853006203	HIGH motif; other site
1133853006204	KMSK motif region; other site
1133853006205	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1133853006206	tRNA binding surface [nucleotide binding]; other site
1133853006207	anticodon binding site; other site
1133853006208	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1133853006209	putative metal binding site [ion binding]; other site
1133853006210	copper homeostasis protein CutC; Provisional; Region: PRK11572
1133853006211	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
1133853006212	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1133853006213	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133853006214	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1133853006215	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1133853006216	molybdopterin cofactor binding site [chemical binding]; other site
1133853006217	substrate binding site [chemical binding]; other site
1133853006218	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1133853006219	molybdopterin cofactor binding site; other site
1133853006220	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853006221	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853006222	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853006223	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853006224	S-adenosylmethionine binding site [chemical binding]; other site
1133853006225	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853006226	S-adenosylmethionine binding site [chemical binding]; other site
1133853006227	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1133853006228	hypothetical protein; Provisional; Region: PRK10302
1133853006229	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1133853006230	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133853006231	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1133853006232	Int/Topo IB signature motif; other site
1133853006233	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1133853006234	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133853006235	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133853006236	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853006237	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
1133853006238	Uncharacterized conserved protein [Function unknown]; Region: COG5532
1133853006239	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133853006240	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853006241	non-specific DNA binding site [nucleotide binding]; other site
1133853006242	salt bridge; other site
1133853006243	sequence-specific DNA binding site [nucleotide binding]; other site
1133853006244	Predicted transcriptional regulator [Transcription]; Region: COG2932
1133853006245	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853006246	Catalytic site [active]
1133853006247	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853006248	non-specific DNA binding site [nucleotide binding]; other site
1133853006249	salt bridge; other site
1133853006250	sequence-specific DNA binding site [nucleotide binding]; other site
1133853006251	Ash protein family; Region: Phage_ASH; pfam10554
1133853006252	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1133853006253	Helix-turn-helix domain; Region: HTH_36; pfam13730
1133853006254	PerC transcriptional activator; Region: PerC; pfam06069
1133853006255	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1133853006256	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1133853006257	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
1133853006258	KilA-N domain; Region: KilA-N; pfam04383
1133853006259	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1133853006260	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133853006261	putative recombination protein RecB; Provisional; Region: PRK13909
1133853006262	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1133853006263	MarR family; Region: MarR_2; cl17246
1133853006264	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853006265	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853006266	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133853006267	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133853006268	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
1133853006269	Protein of unknown function (DUF826); Region: DUF826; pfam05696
1133853006270	Lysis protein S; Region: Lysis_S; pfam04971
1133853006271	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
1133853006272	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133853006273	catalytic residues [active]
1133853006274	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1133853006275	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1133853006276	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1133853006277	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133853006278	gpW; Region: gpW; pfam02831
1133853006279	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1133853006280	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1133853006281	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133853006282	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1133853006283	tandem repeat interface [polypeptide binding]; other site
1133853006284	oligomer interface [polypeptide binding]; other site
1133853006285	active site residues [active]
1133853006286	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133853006287	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133853006288	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133853006289	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133853006290	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133853006291	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133853006292	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133853006293	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133853006294	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
1133853006295	Minor tail protein T; Region: Phage_tail_T; pfam06223
1133853006296	Phage-related protein [Function unknown]; Region: COG4718
1133853006297	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133853006298	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133853006299	MPN+ (JAMM) motif; other site
1133853006300	Zinc-binding site [ion binding]; other site
1133853006301	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133853006302	NlpC/P60 family; Region: NLPC_P60; cl17555
1133853006303	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133853006304	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133853006305	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133853006306	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1133853006307	Interdomain contacts; other site
1133853006308	Cytokine receptor motif; other site
1133853006309	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133853006310	Fibronectin type III protein; Region: DUF3672; pfam12421
1133853006311	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
1133853006312	Phage Tail Collar Domain; Region: Collar; pfam07484
1133853006313	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133853006314	DinI-like family; Region: DinI; pfam06183
1133853006315	Isochorismatase family; Region: Isochorismatase; pfam00857
1133853006316	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1133853006317	catalytic triad [active]
1133853006318	conserved cis-peptide bond; other site
1133853006319	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1133853006320	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1133853006321	dimer interface [polypeptide binding]; other site
1133853006322	anticodon binding site; other site
1133853006323	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1133853006324	homodimer interface [polypeptide binding]; other site
1133853006325	motif 1; other site
1133853006326	active site
1133853006327	motif 2; other site
1133853006328	GAD domain; Region: GAD; pfam02938
1133853006329	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1133853006330	motif 3; other site
1133853006331	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1133853006332	nudix motif; other site
1133853006333	hypothetical protein; Validated; Region: PRK00110
1133853006334	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1133853006335	active site
1133853006336	putative DNA-binding cleft [nucleotide binding]; other site
1133853006337	dimer interface [polypeptide binding]; other site
1133853006338	hypothetical protein; Provisional; Region: PRK11470
1133853006339	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1133853006340	RuvA N terminal domain; Region: RuvA_N; pfam01330
1133853006341	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1133853006342	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1133853006343	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853006344	Walker A motif; other site
1133853006345	ATP binding site [chemical binding]; other site
1133853006346	Walker B motif; other site
1133853006347	arginine finger; other site
1133853006348	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1133853006349	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1133853006350	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853006351	ABC-ATPase subunit  interface; other site
1133853006352	dimer interface [polypeptide binding]; other site
1133853006353	putative PBP binding regions; other site
1133853006354	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1133853006355	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1133853006356	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1133853006357	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1133853006358	metal binding site [ion binding]; metal-binding site
1133853006359	putative peptidase; Provisional; Region: PRK11649
1133853006360	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1133853006361	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853006362	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133853006363	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1133853006364	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133853006365	putative acyl-acceptor binding pocket; other site
1133853006366	pyruvate kinase; Provisional; Region: PRK05826
1133853006367	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1133853006368	domain interfaces; other site
1133853006369	active site
1133853006370	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1133853006371	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133853006372	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133853006373	putative active site [active]
1133853006374	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1133853006375	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1133853006376	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1133853006377	phosphogluconate dehydratase; Validated; Region: PRK09054
1133853006378	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1133853006379	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1133853006380	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1133853006381	active site
1133853006382	intersubunit interface [polypeptide binding]; other site
1133853006383	catalytic residue [active]
1133853006384	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1133853006385	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133853006386	ATP-grasp domain; Region: ATP-grasp; pfam02222
1133853006387	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1133853006388	hypothetical protein; Provisional; Region: PRK13680
1133853006389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1133853006390	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1133853006391	putative metal binding site [ion binding]; other site
1133853006392	protease 2; Provisional; Region: PRK10115
1133853006393	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1133853006394	exodeoxyribonuclease X; Provisional; Region: PRK07983
1133853006395	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1133853006396	active site
1133853006397	catalytic site [active]
1133853006398	substrate binding site [chemical binding]; other site
1133853006399	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1133853006400	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1133853006401	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1133853006402	hypothetical protein; Provisional; Region: PRK10301
1133853006403	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1133853006404	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1133853006405	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1133853006406	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1133853006407	active site
1133853006408	metal binding site [ion binding]; metal-binding site
1133853006409	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1133853006410	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1133853006411	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1133853006412	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853006413	S-adenosylmethionine binding site [chemical binding]; other site
1133853006414	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1133853006415	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1133853006416	mce related protein; Region: MCE; pfam02470
1133853006417	mce related protein; Region: MCE; pfam02470
1133853006418	mce related protein; Region: MCE; pfam02470
1133853006419	mce related protein; Region: MCE; pfam02470
1133853006420	mce related protein; Region: MCE; pfam02470
1133853006421	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
1133853006422	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133853006423	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133853006424	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1133853006425	GAF domain; Region: GAF_2; pfam13185
1133853006426	ProP expression regulator; Provisional; Region: PRK04950
1133853006427	ProQ/FINO family; Region: ProQ; pfam04352
1133853006428	carboxy-terminal protease; Provisional; Region: PRK11186
1133853006429	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1133853006430	protein binding site [polypeptide binding]; other site
1133853006431	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1133853006432	Catalytic dyad [active]
1133853006433	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1133853006434	heat shock protein HtpX; Provisional; Region: PRK05457
1133853006435	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006436	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853006437	putative substrate translocation pore; other site
1133853006438	Predicted integral membrane protein [Function unknown]; Region: COG5521
1133853006439	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1133853006440	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853006441	dimerization interface [polypeptide binding]; other site
1133853006442	putative Zn2+ binding site [ion binding]; other site
1133853006443	putative DNA binding site [nucleotide binding]; other site
1133853006444	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133853006445	YobH-like protein; Region: YobH; pfam13996
1133853006446	PhoPQ regulatory protein; Provisional; Region: PRK10299
1133853006447	YebO-like protein; Region: YebO; pfam13974
1133853006448	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
1133853006449	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133853006450	DNA-binding site [nucleotide binding]; DNA binding site
1133853006451	RNA-binding motif; other site
1133853006452	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1133853006453	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853006454	S-adenosylmethionine binding site [chemical binding]; other site
1133853006455	hypothetical protein; Provisional; Region: PRK11469
1133853006456	Domain of unknown function DUF; Region: DUF204; pfam02659
1133853006457	Domain of unknown function DUF; Region: DUF204; pfam02659
1133853006458	Predicted membrane protein [Function unknown]; Region: COG4811
1133853006459	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1133853006460	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1133853006461	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1133853006462	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1133853006463	active pocket/dimerization site; other site
1133853006464	active site
1133853006465	phosphorylation site [posttranslational modification]
1133853006466	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1133853006467	active site
1133853006468	phosphorylation site [posttranslational modification]
1133853006469	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1133853006470	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1133853006471	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133853006472	Transporter associated domain; Region: CorC_HlyC; smart01091
1133853006473	phage resistance protein; Provisional; Region: PRK10551
1133853006474	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133853006475	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853006476	L-serine deaminase; Provisional; Region: PRK15023
1133853006477	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1133853006478	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1133853006479	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1133853006480	putative active site [active]
1133853006481	putative CoA binding site [chemical binding]; other site
1133853006482	nudix motif; other site
1133853006483	metal binding site [ion binding]; metal-binding site
1133853006484	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1133853006485	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1133853006486	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1133853006487	hypothetical protein; Provisional; Region: PRK05114
1133853006488	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1133853006489	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1133853006490	homotrimer interaction site [polypeptide binding]; other site
1133853006491	putative active site [active]
1133853006492	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1133853006493	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1133853006494	DEAD_2; Region: DEAD_2; pfam06733
1133853006495	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1133853006496	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1133853006497	Glycoprotease family; Region: Peptidase_M22; pfam00814
1133853006498	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
1133853006499	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1133853006500	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1133853006501	acyl-activating enzyme (AAE) consensus motif; other site
1133853006502	putative AMP binding site [chemical binding]; other site
1133853006503	putative active site [active]
1133853006504	putative CoA binding site [chemical binding]; other site
1133853006505	ribonuclease D; Provisional; Region: PRK10829
1133853006506	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1133853006507	catalytic site [active]
1133853006508	putative active site [active]
1133853006509	putative substrate binding site [chemical binding]; other site
1133853006510	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1133853006511	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1133853006512	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1133853006513	FMN-binding pocket [chemical binding]; other site
1133853006514	flavin binding motif; other site
1133853006515	phosphate binding motif [ion binding]; other site
1133853006516	beta-alpha-beta structure motif; other site
1133853006517	NAD binding pocket [chemical binding]; other site
1133853006518	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853006519	catalytic loop [active]
1133853006520	iron binding site [ion binding]; other site
1133853006521	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1133853006522	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1133853006523	[2Fe-2S] cluster binding site [ion binding]; other site
1133853006524	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
1133853006525	putative alpha subunit interface [polypeptide binding]; other site
1133853006526	putative active site [active]
1133853006527	putative substrate binding site [chemical binding]; other site
1133853006528	Fe binding site [ion binding]; other site
1133853006529	putative transporter; Provisional; Region: PRK09950
1133853006530	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1133853006531	tartrate dehydrogenase; Region: TTC; TIGR02089
1133853006532	transcriptional activator TtdR; Provisional; Region: PRK09801
1133853006533	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853006534	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1133853006535	putative effector binding pocket; other site
1133853006536	putative dimerization interface [polypeptide binding]; other site
1133853006537	leucine export protein LeuE; Provisional; Region: PRK10958
1133853006538	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1133853006539	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1133853006540	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1133853006541	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1133853006542	Probable transposase; Region: OrfB_IS605; pfam01385
1133853006543	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1133853006544	hypothetical protein; Provisional; Region: PRK10457
1133853006545	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1133853006546	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133853006547	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853006548	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853006549	metal binding site [ion binding]; metal-binding site
1133853006550	active site
1133853006551	I-site; other site
1133853006552	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1133853006553	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1133853006554	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1133853006555	cyanate transporter; Region: CynX; TIGR00896
1133853006556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006557	putative substrate translocation pore; other site
1133853006558	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853006559	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853006560	Predicted membrane protein [Function unknown]; Region: COG2707
1133853006561	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1133853006562	putative deacylase active site [active]
1133853006563	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853006564	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853006565	metal binding site [ion binding]; metal-binding site
1133853006566	active site
1133853006567	I-site; other site
1133853006568	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853006569	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853006570	metal binding site [ion binding]; metal-binding site
1133853006571	active site
1133853006572	I-site; other site
1133853006573	hypothetical protein; Provisional; Region: PRK05325
1133853006574	PrkA family serine protein kinase; Provisional; Region: PRK15455
1133853006575	AAA ATPase domain; Region: AAA_16; pfam13191
1133853006576	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1133853006577	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1133853006578	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853006579	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853006580	active site
1133853006581	catalytic tetrad [active]
1133853006582	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1133853006583	active site
1133853006584	phosphate binding residues; other site
1133853006585	catalytic residues [active]
1133853006586	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1133853006587	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1133853006588	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1133853006589	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1133853006590	SelR domain; Region: SelR; pfam01641
1133853006591	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1133853006592	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853006593	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
1133853006594	putative NAD(P) binding site [chemical binding]; other site
1133853006595	catalytic Zn binding site [ion binding]; other site
1133853006596	structural Zn binding site [ion binding]; other site
1133853006597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006598	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006599	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853006600	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1133853006601	inhibitor binding site; inhibition site
1133853006602	catalytic Zn binding site [ion binding]; other site
1133853006603	structural Zn binding site [ion binding]; other site
1133853006604	NADP binding site [chemical binding]; other site
1133853006605	tetramer interface [polypeptide binding]; other site
1133853006606	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1133853006607	intersubunit interface [polypeptide binding]; other site
1133853006608	active site
1133853006609	zinc binding site [ion binding]; other site
1133853006610	Na+ binding site [ion binding]; other site
1133853006611	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853006612	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1133853006613	substrate binding site [chemical binding]; other site
1133853006614	ATP binding site [chemical binding]; other site
1133853006615	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853006616	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853006617	active site
1133853006618	catalytic tetrad [active]
1133853006619	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133853006620	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133853006621	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853006622	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1133853006623	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006624	putative substrate translocation pore; other site
1133853006625	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006626	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1133853006627	Isochorismatase family; Region: Isochorismatase; pfam00857
1133853006628	catalytic triad [active]
1133853006629	metal binding site [ion binding]; metal-binding site
1133853006630	conserved cis-peptide bond; other site
1133853006631	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1133853006632	active site
1133853006633	homodimer interface [polypeptide binding]; other site
1133853006634	protease 4; Provisional; Region: PRK10949
1133853006635	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1133853006636	tandem repeat interface [polypeptide binding]; other site
1133853006637	oligomer interface [polypeptide binding]; other site
1133853006638	active site residues [active]
1133853006639	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1133853006640	tandem repeat interface [polypeptide binding]; other site
1133853006641	oligomer interface [polypeptide binding]; other site
1133853006642	active site residues [active]
1133853006643	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1133853006644	putative FMN binding site [chemical binding]; other site
1133853006645	selenophosphate synthetase; Provisional; Region: PRK00943
1133853006646	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1133853006647	dimerization interface [polypeptide binding]; other site
1133853006648	putative ATP binding site [chemical binding]; other site
1133853006649	DNA topoisomerase III; Provisional; Region: PRK07726
1133853006650	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1133853006651	active site
1133853006652	putative interdomain interaction site [polypeptide binding]; other site
1133853006653	putative metal-binding site [ion binding]; other site
1133853006654	putative nucleotide binding site [chemical binding]; other site
1133853006655	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1133853006656	domain I; other site
1133853006657	DNA binding groove [nucleotide binding]
1133853006658	phosphate binding site [ion binding]; other site
1133853006659	domain II; other site
1133853006660	domain III; other site
1133853006661	nucleotide binding site [chemical binding]; other site
1133853006662	catalytic site [active]
1133853006663	domain IV; other site
1133853006664	Protein of unknown function (DUF1266); Region: DUF1266; cl14673
1133853006665	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853006666	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853006667	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853006668	Protein of unknown function (DUF1266); Region: DUF1266; cl14673
1133853006669	glutamate dehydrogenase; Provisional; Region: PRK09414
1133853006670	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1133853006671	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1133853006672	NAD(P) binding site [chemical binding]; other site
1133853006673	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1133853006674	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1133853006675	active site
1133853006676	8-oxo-dGMP binding site [chemical binding]; other site
1133853006677	nudix motif; other site
1133853006678	metal binding site [ion binding]; metal-binding site
1133853006679	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1133853006680	Rhodanese Homology Domain; Region: RHOD; smart00450
1133853006681	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1133853006682	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1133853006683	active site residue [active]
1133853006684	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1133853006685	active site residue [active]
1133853006686	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
1133853006687	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853006688	Walker A/P-loop; other site
1133853006689	ATP binding site [chemical binding]; other site
1133853006690	Q-loop/lid; other site
1133853006691	ABC transporter signature motif; other site
1133853006692	Walker B; other site
1133853006693	D-loop; other site
1133853006694	H-loop/switch region; other site
1133853006695	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
1133853006696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853006697	ABC-ATPase subunit interface; other site
1133853006698	putative PBP binding loops; other site
1133853006699	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
1133853006700	hypothetical protein; Provisional; Region: PRK11622
1133853006701	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1133853006702	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1133853006703	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1133853006704	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1133853006705	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1133853006706	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1133853006707	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1133853006708	putative catalytic site [active]
1133853006709	putative phosphate binding site [ion binding]; other site
1133853006710	active site
1133853006711	metal binding site A [ion binding]; metal-binding site
1133853006712	DNA binding site [nucleotide binding]
1133853006713	putative AP binding site [nucleotide binding]; other site
1133853006714	putative metal binding site B [ion binding]; other site
1133853006715	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1133853006716	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853006717	inhibitor-cofactor binding pocket; inhibition site
1133853006718	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853006719	catalytic residue [active]
1133853006720	arginine succinyltransferase; Provisional; Region: PRK10456
1133853006721	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1133853006722	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1133853006723	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1133853006724	NAD(P) binding site [chemical binding]; other site
1133853006725	catalytic residues [active]
1133853006726	succinylarginine dihydrolase; Provisional; Region: PRK13281
1133853006727	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1133853006728	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1133853006729	putative active site [active]
1133853006730	Zn binding site [ion binding]; other site
1133853006731	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1133853006732	dimer interface [polypeptide binding]; other site
1133853006733	hypothetical protein; Provisional; Region: PRK11396
1133853006734	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1133853006735	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1133853006736	GIY-YIG motif/motif A; other site
1133853006737	active site
1133853006738	catalytic site [active]
1133853006739	putative DNA binding site [nucleotide binding]; other site
1133853006740	metal binding site [ion binding]; metal-binding site
1133853006741	NAD+ synthetase; Region: nadE; TIGR00552
1133853006742	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1133853006743	homodimer interface [polypeptide binding]; other site
1133853006744	NAD binding pocket [chemical binding]; other site
1133853006745	ATP binding pocket [chemical binding]; other site
1133853006746	Mg binding site [ion binding]; other site
1133853006747	active-site loop [active]
1133853006748	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1133853006749	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1133853006750	active site
1133853006751	P-loop; other site
1133853006752	phosphorylation site [posttranslational modification]
1133853006753	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1133853006754	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1133853006755	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1133853006756	methionine cluster; other site
1133853006757	active site
1133853006758	phosphorylation site [posttranslational modification]
1133853006759	metal binding site [ion binding]; metal-binding site
1133853006760	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1133853006761	Cupin domain; Region: Cupin_2; pfam07883
1133853006762	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853006763	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1133853006764	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1133853006765	NAD binding site [chemical binding]; other site
1133853006766	sugar binding site [chemical binding]; other site
1133853006767	divalent metal binding site [ion binding]; other site
1133853006768	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133853006769	dimer interface [polypeptide binding]; other site
1133853006770	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1133853006771	putative active site [active]
1133853006772	YdjC motif; other site
1133853006773	Mg binding site [ion binding]; other site
1133853006774	putative homodimer interface [polypeptide binding]; other site
1133853006775	hydroperoxidase II; Provisional; Region: katE; PRK11249
1133853006776	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1133853006777	tetramer interface [polypeptide binding]; other site
1133853006778	heme binding pocket [chemical binding]; other site
1133853006779	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1133853006780	domain interactions; other site
1133853006781	cell division modulator; Provisional; Region: PRK10113
1133853006782	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1133853006783	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1133853006784	inner membrane protein; Provisional; Region: PRK11648
1133853006785	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1133853006786	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1133853006787	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853006788	motif II; other site
1133853006789	YniB-like protein; Region: YniB; pfam14002
1133853006790	Phosphotransferase enzyme family; Region: APH; pfam01636
1133853006791	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1133853006792	active site
1133853006793	ATP binding site [chemical binding]; other site
1133853006794	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1133853006795	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1133853006796	6-phosphofructokinase 2; Provisional; Region: PRK10294
1133853006797	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1133853006798	putative substrate binding site [chemical binding]; other site
1133853006799	putative ATP binding site [chemical binding]; other site
1133853006800	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1133853006801	potential frameshift: common BLAST hit: gi|218705219|ref|YP_002412738.1| putative ankyrin repeat regulatory protein
1133853006802	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1133853006803	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1133853006804	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1133853006805	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1133853006806	active site
1133853006807	dimer interface [polypeptide binding]; other site
1133853006808	motif 1; other site
1133853006809	motif 2; other site
1133853006810	motif 3; other site
1133853006811	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1133853006812	anticodon binding site; other site
1133853006813	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1133853006814	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1133853006815	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1133853006816	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1133853006817	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1133853006818	23S rRNA binding site [nucleotide binding]; other site
1133853006819	L21 binding site [polypeptide binding]; other site
1133853006820	L13 binding site [polypeptide binding]; other site
1133853006821	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1133853006822	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1133853006823	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1133853006824	dimer interface [polypeptide binding]; other site
1133853006825	motif 1; other site
1133853006826	active site
1133853006827	motif 2; other site
1133853006828	motif 3; other site
1133853006829	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1133853006830	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1133853006831	putative tRNA-binding site [nucleotide binding]; other site
1133853006832	B3/4 domain; Region: B3_4; pfam03483
1133853006833	tRNA synthetase B5 domain; Region: B5; smart00874
1133853006834	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1133853006835	dimer interface [polypeptide binding]; other site
1133853006836	motif 1; other site
1133853006837	motif 3; other site
1133853006838	motif 2; other site
1133853006839	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1133853006840	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1133853006841	IHF dimer interface [polypeptide binding]; other site
1133853006842	IHF - DNA interface [nucleotide binding]; other site
1133853006843	Hok/gef family; Region: HOK_GEF; pfam01848
1133853006844	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1133853006845	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1133853006846	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1133853006847	tail protein; Provisional; Region: D; PHA02561
1133853006848	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
1133853006849	Phage tail tube protein FII; Region: Phage_tube; cl01390
1133853006850	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1133853006851	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1133853006852	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1133853006853	Phage protein U [General function prediction only]; Region: COG3499
1133853006854	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
1133853006855	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1133853006856	trimer interface [polypeptide binding]; other site
1133853006857	active site
1133853006858	substrate binding site [chemical binding]; other site
1133853006859	CoA binding site [chemical binding]; other site
1133853006860	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133853006861	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1133853006862	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853006863	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853006864	Phage Tail Collar Domain; Region: Collar; pfam07484
1133853006865	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1133853006866	Baseplate J-like protein; Region: Baseplate_J; cl01294
1133853006867	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1133853006868	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1133853006869	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
1133853006870	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
1133853006871	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1133853006872	Domain of unknown function (DUF1737); Region: DUF1737; cl10503
1133853006873	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133853006874	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
1133853006875	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1133853006876	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1133853006877	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1133853006878	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1133853006879	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1133853006880	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1133853006881	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
1133853006882	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
1133853006883	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1133853006884	terminase ATPase subunit; Provisional; Region: P; PHA02535
1133853006885	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1133853006886	Phage portal protein; Region: Phage_portal; pfam04860
1133853006887	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
1133853006888	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1133853006889	Mg binding site [ion binding]; other site
1133853006890	nucleotide binding site [chemical binding]; other site
1133853006891	putative protofilament interface [polypeptide binding]; other site
1133853006892	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1133853006893	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133853006894	MarR family; Region: MarR_2; pfam12802
1133853006895	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853006896	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133853006897	non-specific DNA binding site [nucleotide binding]; other site
1133853006898	salt bridge; other site
1133853006899	sequence-specific DNA binding site [nucleotide binding]; other site
1133853006900	integrase; Provisional; Region: int; PHA02601
1133853006901	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1133853006902	active site
1133853006903	DNA binding site [nucleotide binding]
1133853006904	Int/Topo IB signature motif; other site
1133853006905	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1133853006906	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853006907	ABC-ATPase subunit  interface; other site
1133853006908	dimer interface [polypeptide binding]; other site
1133853006909	putative PBP binding regions; other site
1133853006910	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1133853006911	catalytic residues [active]
1133853006912	dimer interface [polypeptide binding]; other site
1133853006913	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1133853006914	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133853006915	Walker A/P-loop; other site
1133853006916	ATP binding site [chemical binding]; other site
1133853006917	Q-loop/lid; other site
1133853006918	ABC transporter signature motif; other site
1133853006919	Walker B; other site
1133853006920	D-loop; other site
1133853006921	H-loop/switch region; other site
1133853006922	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133853006923	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1133853006924	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1133853006925	hypothetical protein; Validated; Region: PRK00029
1133853006926	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
1133853006927	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1133853006928	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1133853006929	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1133853006930	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1133853006931	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1133853006932	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133853006933	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133853006934	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1133853006935	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1133853006936	acyl-activating enzyme (AAE) consensus motif; other site
1133853006937	putative AMP binding site [chemical binding]; other site
1133853006938	putative active site [active]
1133853006939	putative CoA binding site [chemical binding]; other site
1133853006940	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1133853006941	oxidoreductase; Provisional; Region: PRK10015
1133853006942	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1133853006943	Electron transfer flavoprotein domain; Region: ETF; smart00893
1133853006944	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1133853006945	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1133853006946	Ligand binding site [chemical binding]; other site
1133853006947	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1133853006948	Cupin domain; Region: Cupin_2; pfam07883
1133853006949	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853006950	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853006951	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1133853006952	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1133853006953	active site
1133853006954	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1133853006955	Coenzyme A transferase; Region: CoA_trans; smart00882
1133853006956	Coenzyme A transferase; Region: CoA_trans; cl17247
1133853006957	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1133853006958	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1133853006959	active site
1133853006960	catalytic residue [active]
1133853006961	dimer interface [polypeptide binding]; other site
1133853006962	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1133853006963	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1133853006964	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1133853006965	shikimate binding site; other site
1133853006966	NAD(P) binding site [chemical binding]; other site
1133853006967	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006968	putative substrate translocation pore; other site
1133853006969	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853006970	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853006971	putative substrate translocation pore; other site
1133853006972	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1133853006973	putative inner membrane protein; Provisional; Region: PRK10983
1133853006974	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1133853006975	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1133853006976	FAD binding domain; Region: FAD_binding_4; pfam01565
1133853006977	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1133853006978	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133853006979	CoenzymeA binding site [chemical binding]; other site
1133853006980	subunit interaction site [polypeptide binding]; other site
1133853006981	PHB binding site; other site
1133853006982	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1133853006983	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1133853006984	putative ABC transporter; Region: ycf24; CHL00085
1133853006985	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1133853006986	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1133853006987	Walker A/P-loop; other site
1133853006988	ATP binding site [chemical binding]; other site
1133853006989	Q-loop/lid; other site
1133853006990	ABC transporter signature motif; other site
1133853006991	Walker B; other site
1133853006992	D-loop; other site
1133853006993	H-loop/switch region; other site
1133853006994	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1133853006995	FeS assembly protein SufD; Region: sufD; TIGR01981
1133853006996	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1133853006997	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1133853006998	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853006999	catalytic residue [active]
1133853007000	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1133853007001	L,D-transpeptidase; Provisional; Region: PRK10190
1133853007002	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853007003	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853007004	murein lipoprotein; Provisional; Region: PRK15396
1133853007005	pyruvate kinase; Provisional; Region: PRK09206
1133853007006	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1133853007007	domain interfaces; other site
1133853007008	active site
1133853007009	hypothetical protein; Provisional; Region: PRK10292
1133853007010	hypothetical protein; Provisional; Region: PRK09898
1133853007011	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853007012	putative oxidoreductase; Provisional; Region: PRK09849
1133853007013	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
1133853007014	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
1133853007015	hypothetical protein; Provisional; Region: PRK09947
1133853007016	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1133853007017	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1133853007018	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1133853007019	hypothetical protein; Provisional; Region: PRK09946
1133853007020	hypothetical protein; Provisional; Region: PRK09897
1133853007021	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1133853007022	putative monooxygenase; Provisional; Region: PRK11118
1133853007023	hypothetical protein; Provisional; Region: PRK09945
1133853007024	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133853007025	multidrug efflux protein; Reviewed; Region: PRK01766
1133853007026	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1133853007027	cation binding site [ion binding]; other site
1133853007028	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1133853007029	Lumazine binding domain; Region: Lum_binding; pfam00677
1133853007030	Lumazine binding domain; Region: Lum_binding; pfam00677
1133853007031	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1133853007032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1133853007033	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853007034	S-adenosylmethionine binding site [chemical binding]; other site
1133853007035	putative transporter; Provisional; Region: PRK11043
1133853007036	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007037	putative substrate translocation pore; other site
1133853007038	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1133853007039	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853007040	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853007041	dimerization interface [polypeptide binding]; other site
1133853007042	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1133853007043	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853007044	DNA binding site [nucleotide binding]
1133853007045	domain linker motif; other site
1133853007046	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1133853007047	dimerization interface [polypeptide binding]; other site
1133853007048	ligand binding site [chemical binding]; other site
1133853007049	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007050	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853007051	putative substrate translocation pore; other site
1133853007052	superoxide dismutase; Provisional; Region: PRK10543
1133853007053	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1133853007054	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1133853007055	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133853007056	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133853007057	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1133853007058	putative GSH binding site [chemical binding]; other site
1133853007059	catalytic residues [active]
1133853007060	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853007061	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
1133853007062	ATP binding site [chemical binding]; other site
1133853007063	putative Mg++ binding site [ion binding]; other site
1133853007064	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853007065	nucleotide binding region [chemical binding]; other site
1133853007066	ATP-binding site [chemical binding]; other site
1133853007067	DEAD/H associated; Region: DEAD_assoc; pfam08494
1133853007068	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1133853007069	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1133853007070	dimer interface [polypeptide binding]; other site
1133853007071	catalytic site [active]
1133853007072	putative active site [active]
1133853007073	putative substrate binding site [chemical binding]; other site
1133853007074	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1133853007075	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1133853007076	dimer interface [polypeptide binding]; other site
1133853007077	active site
1133853007078	metal binding site [ion binding]; metal-binding site
1133853007079	glutathione binding site [chemical binding]; other site
1133853007080	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1133853007081	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1133853007082	FMN binding site [chemical binding]; other site
1133853007083	active site
1133853007084	substrate binding site [chemical binding]; other site
1133853007085	catalytic residue [active]
1133853007086	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133853007087	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853007088	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1133853007089	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853007090	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853007091	active site
1133853007092	catalytic tetrad [active]
1133853007093	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1133853007094	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1133853007095	E-class dimer interface [polypeptide binding]; other site
1133853007096	P-class dimer interface [polypeptide binding]; other site
1133853007097	active site
1133853007098	Cu2+ binding site [ion binding]; other site
1133853007099	Zn2+ binding site [ion binding]; other site
1133853007100	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1133853007101	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133853007102	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1133853007103	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853007104	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853007105	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
1133853007106	transcriptional regulator SlyA; Provisional; Region: PRK03573
1133853007107	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1133853007108	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1133853007109	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
1133853007110	lysozyme inhibitor; Provisional; Region: PRK11372
1133853007111	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1133853007112	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1133853007113	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1133853007114	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1133853007115	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1133853007116	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1133853007117	active site
1133853007118	HIGH motif; other site
1133853007119	dimer interface [polypeptide binding]; other site
1133853007120	KMSKS motif; other site
1133853007121	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853007122	RNA binding surface [nucleotide binding]; other site
1133853007123	pyridoxamine kinase; Validated; Region: PRK05756
1133853007124	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1133853007125	dimer interface [polypeptide binding]; other site
1133853007126	pyridoxal binding site [chemical binding]; other site
1133853007127	ATP binding site [chemical binding]; other site
1133853007128	glutathionine S-transferase; Provisional; Region: PRK10542
1133853007129	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1133853007130	C-terminal domain interface [polypeptide binding]; other site
1133853007131	GSH binding site (G-site) [chemical binding]; other site
1133853007132	dimer interface [polypeptide binding]; other site
1133853007133	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1133853007134	N-terminal domain interface [polypeptide binding]; other site
1133853007135	dimer interface [polypeptide binding]; other site
1133853007136	substrate binding pocket (H-site) [chemical binding]; other site
1133853007137	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133853007138	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007139	putative substrate translocation pore; other site
1133853007140	POT family; Region: PTR2; pfam00854
1133853007141	endonuclease III; Provisional; Region: PRK10702
1133853007142	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1133853007143	minor groove reading motif; other site
1133853007144	helix-hairpin-helix signature motif; other site
1133853007145	substrate binding pocket [chemical binding]; other site
1133853007146	active site
1133853007147	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1133853007148	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1133853007149	electron transport complex protein RnfG; Validated; Region: PRK01908
1133853007150	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1133853007151	electron transport complex protein RnfC; Provisional; Region: PRK05035
1133853007152	SLBB domain; Region: SLBB; pfam10531
1133853007153	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853007154	electron transport complex protein RnfB; Provisional; Region: PRK05113
1133853007155	Putative Fe-S cluster; Region: FeS; pfam04060
1133853007156	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853007157	electron transport complex protein RsxA; Provisional; Region: PRK05151
1133853007158	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1133853007159	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1133853007160	putative oxidoreductase; Provisional; Region: PRK11579
1133853007161	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133853007162	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133853007163	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1133853007164	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1133853007165	active site
1133853007166	purine riboside binding site [chemical binding]; other site
1133853007167	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1133853007168	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853007169	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853007170	homodimer interface [polypeptide binding]; other site
1133853007171	catalytic residue [active]
1133853007172	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1133853007173	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1133853007174	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853007175	active site turn [active]
1133853007176	phosphorylation site [posttranslational modification]
1133853007177	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1133853007178	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853007179	DNA binding site [nucleotide binding]
1133853007180	domain linker motif; other site
1133853007181	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
1133853007182	putative dimerization interface [polypeptide binding]; other site
1133853007183	putative ligand binding site [chemical binding]; other site
1133853007184	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
1133853007185	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
1133853007186	NAD binding site [chemical binding]; other site
1133853007187	substrate binding site [chemical binding]; other site
1133853007188	homotetramer interface [polypeptide binding]; other site
1133853007189	homodimer interface [polypeptide binding]; other site
1133853007190	active site
1133853007191	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133853007192	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853007193	beta-D-glucuronidase; Provisional; Region: PRK10150
1133853007194	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1133853007195	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1133853007196	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1133853007197	glucuronide transporter; Provisional; Region: PRK09848
1133853007198	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007199	putative substrate translocation pore; other site
1133853007200	putative outer membrane porin protein; Provisional; Region: PRK11379
1133853007201	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1133853007202	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1133853007203	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1133853007204	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1133853007205	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1133853007206	fumarate hydratase; Provisional; Region: PRK15389
1133853007207	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1133853007208	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1133853007209	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1133853007210	Class II fumarases; Region: Fumarase_classII; cd01362
1133853007211	active site
1133853007212	tetramer interface [polypeptide binding]; other site
1133853007213	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1133853007214	sensor protein RstB; Provisional; Region: PRK10604
1133853007215	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853007216	dimerization interface [polypeptide binding]; other site
1133853007217	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853007218	dimer interface [polypeptide binding]; other site
1133853007219	phosphorylation site [posttranslational modification]
1133853007220	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853007221	ATP binding site [chemical binding]; other site
1133853007222	Mg2+ binding site [ion binding]; other site
1133853007223	G-X-G motif; other site
1133853007224	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1133853007225	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853007226	active site
1133853007227	phosphorylation site [posttranslational modification]
1133853007228	intermolecular recognition site; other site
1133853007229	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853007230	DNA binding site [nucleotide binding]
1133853007231	GlpM protein; Region: GlpM; pfam06942
1133853007232	dihydromonapterin reductase; Provisional; Region: PRK06483
1133853007233	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
1133853007234	NADP binding site [chemical binding]; other site
1133853007235	substrate binding pocket [chemical binding]; other site
1133853007236	active site
1133853007237	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1133853007238	Spore germination protein; Region: Spore_permease; cl17796
1133853007239	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853007240	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853007241	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853007242	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1133853007243	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1133853007244	ligand binding site [chemical binding]; other site
1133853007245	homodimer interface [polypeptide binding]; other site
1133853007246	NAD(P) binding site [chemical binding]; other site
1133853007247	trimer interface B [polypeptide binding]; other site
1133853007248	trimer interface A [polypeptide binding]; other site
1133853007249	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1133853007250	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1133853007251	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1133853007252	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1133853007253	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1133853007254	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1133853007255	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1133853007256	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1133853007257	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1133853007258	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007259	putative substrate translocation pore; other site
1133853007260	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1133853007261	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853007262	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1133853007263	dimerization interface [polypeptide binding]; other site
1133853007264	substrate binding pocket [chemical binding]; other site
1133853007265	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1133853007266	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133853007267	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853007268	nucleotide binding site [chemical binding]; other site
1133853007269	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1133853007270	AAA domain; Region: AAA_26; pfam13500
1133853007271	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1133853007272	Cl- selectivity filter; other site
1133853007273	Cl- binding residues [ion binding]; other site
1133853007274	pore gating glutamate residue; other site
1133853007275	dimer interface [polypeptide binding]; other site
1133853007276	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1133853007277	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1133853007278	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133853007279	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1133853007280	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
1133853007281	Int/Topo IB signature motif; other site
1133853007282	Helix-turn-helix domain; Region: HTH_17; pfam12728
1133853007283	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133853007284	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1133853007285	phage recombination protein Bet; Region: bet_lambda; TIGR01913
1133853007286	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
1133853007287	similar to Exodeoxyribonuclease VIII (fragment) from phage origin
1133853007288	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1133853007289	Domain of unknown function DUF1828; Region: DUF1828; pfam08861
1133853007290	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853007291	non-specific DNA binding site [nucleotide binding]; other site
1133853007292	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1133853007293	salt bridge; other site
1133853007294	sequence-specific DNA binding site [nucleotide binding]; other site
1133853007295	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853007296	Catalytic site [active]
1133853007297	Cro; Region: Cro; pfam09048
1133853007298	Bacteriophage CII protein; Region: Phage_CII; pfam05269
1133853007299	primosomal protein DnaI; Provisional; Region: PRK02854
1133853007300	putative replication protein; Provisional; Region: PRK12377
1133853007301	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853007302	Walker A motif; other site
1133853007303	ATP binding site [chemical binding]; other site
1133853007304	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
1133853007305	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1133853007306	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133853007307	Hok/gef family; Region: HOK_GEF; pfam01848
1133853007308	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1133853007309	Predicted transcriptional regulator [Transcription]; Region: COG2944
1133853007310	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853007311	non-specific DNA binding site [nucleotide binding]; other site
1133853007312	salt bridge; other site
1133853007313	sequence-specific DNA binding site [nucleotide binding]; other site
1133853007314	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1133853007315	ORF6N domain; Region: ORF6N; pfam10543
1133853007316	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1133853007317	NinB protein; Region: NinB; pfam05772
1133853007318	NINE Protein; Region: NinE; pfam05322
1133853007319	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1133853007320	Endodeoxyribonuclease RusA; Region: RusA; cl01885
1133853007321	Phage NinH protein; Region: Phage_NinH; pfam06322
1133853007322	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133853007323	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133853007324	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133853007325	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
1133853007326	Protein of unknown function (DUF826); Region: DUF826; pfam05696
1133853007327	Lysis protein S; Region: Lysis_S; pfam04971
1133853007328	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133853007329	catalytic residues [active]
1133853007330	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1133853007331	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1133853007332	catalytic core [active]
1133853007333	large terminase protein; Provisional; Region: 17; PHA02533
1133853007334	large terminase protein; Provisional; Region: 17; PHA02533
1133853007335	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
1133853007336	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133853007337	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133853007338	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133853007339	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1133853007340	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133853007341	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133853007342	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133853007343	Hok/gef family; Region: HOK_GEF; pfam01848
1133853007344	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133853007345	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853007346	DksA-like zinc finger domain containing protein; Region: PHA00080
1133853007347	Phage anti-repressor protein [Transcription]; Region: COG3561
1133853007348	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1133853007349	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1133853007350	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1133853007351	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1133853007352	putative [Fe4-S4] binding site [ion binding]; other site
1133853007353	putative molybdopterin cofactor binding site [chemical binding]; other site
1133853007354	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1133853007355	putative molybdopterin cofactor binding site; other site
1133853007356	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1133853007357	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1133853007358	putative [Fe4-S4] binding site [ion binding]; other site
1133853007359	putative molybdopterin cofactor binding site [chemical binding]; other site
1133853007360	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1133853007361	putative molybdopterin cofactor binding site; other site
1133853007362	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1133853007363	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1133853007364	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1133853007365	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853007366	Coenzyme A binding pocket [chemical binding]; other site
1133853007367	hypothetical protein; Provisional; Region: PRK13659
1133853007368	hypothetical protein; Provisional; Region: PRK02237
1133853007369	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1133853007370	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1133853007371	putative active site pocket [active]
1133853007372	putative metal binding site [ion binding]; other site
1133853007373	putative oxidoreductase; Provisional; Region: PRK10083
1133853007374	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1133853007375	putative NAD(P) binding site [chemical binding]; other site
1133853007376	catalytic Zn binding site [ion binding]; other site
1133853007377	structural Zn binding site [ion binding]; other site
1133853007378	metabolite-proton symporter; Region: 2A0106; TIGR00883
1133853007379	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007380	putative substrate translocation pore; other site
1133853007381	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1133853007382	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133853007383	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133853007384	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1133853007385	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1133853007386	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853007387	DNA-binding site [nucleotide binding]; DNA binding site
1133853007388	FCD domain; Region: FCD; pfam07729
1133853007389	malonic semialdehyde reductase; Provisional; Region: PRK10538
1133853007390	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1133853007391	putative NAD(P) binding site [chemical binding]; other site
1133853007392	homodimer interface [polypeptide binding]; other site
1133853007393	homotetramer interface [polypeptide binding]; other site
1133853007394	active site
1133853007395	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1133853007396	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1133853007397	active site
1133853007398	Zn binding site [ion binding]; other site
1133853007399	hypothetical protein; Validated; Region: PRK03657
1133853007400	hypothetical protein; Provisional; Region: PRK10053
1133853007401	diguanylate cyclase; Provisional; Region: PRK09894
1133853007402	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1133853007403	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853007404	metal binding site [ion binding]; metal-binding site
1133853007405	active site
1133853007406	I-site; other site
1133853007407	putative transporter; Provisional; Region: PRK10054
1133853007408	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007409	putative substrate translocation pore; other site
1133853007410	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1133853007411	EamA-like transporter family; Region: EamA; pfam00892
1133853007412	EamA-like transporter family; Region: EamA; pfam00892
1133853007413	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1133853007414	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853007415	DNA-binding site [nucleotide binding]; DNA binding site
1133853007416	UTRA domain; Region: UTRA; pfam07702
1133853007417	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1133853007418	active site
1133853007419	P-loop; other site
1133853007420	phosphorylation site [posttranslational modification]
1133853007421	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1133853007422	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1133853007423	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1133853007424	active site
1133853007425	methionine cluster; other site
1133853007426	phosphorylation site [posttranslational modification]
1133853007427	metal binding site [ion binding]; metal-binding site
1133853007428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1133853007429	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1133853007430	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1133853007431	trimer interface; other site
1133853007432	sugar binding site [chemical binding]; other site
1133853007433	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
1133853007434	beta-galactosidase; Region: BGL; TIGR03356
1133853007435	hypothetical protein; Provisional; Region: PRK10106
1133853007436	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1133853007437	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853007438	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1133853007439	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1133853007440	inner membrane protein; Provisional; Region: PRK10995
1133853007441	putative arabinose transporter; Provisional; Region: PRK03545
1133853007442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853007443	putative substrate translocation pore; other site
1133853007444	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853007445	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853007446	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1133853007447	putative dimerization interface [polypeptide binding]; other site
1133853007448	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1133853007449	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1133853007450	NAD(P) binding site [chemical binding]; other site
1133853007451	catalytic residues [active]
1133853007452	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1133853007453	glutaminase; Provisional; Region: PRK00971
1133853007454	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1133853007455	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853007456	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853007457	metal binding site [ion binding]; metal-binding site
1133853007458	active site
1133853007459	I-site; other site
1133853007460	altronate oxidoreductase; Provisional; Region: PRK03643
1133853007461	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133853007462	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133853007463	Predicted membrane protein [Function unknown]; Region: COG3781
1133853007464	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
1133853007465	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853007466	S-adenosylmethionine binding site [chemical binding]; other site
1133853007467	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1133853007468	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1133853007469	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1133853007470	putative active site; other site
1133853007471	catalytic residue [active]
1133853007472	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1133853007473	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1133853007474	ligand binding site [chemical binding]; other site
1133853007475	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853007476	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853007477	TM-ABC transporter signature motif; other site
1133853007478	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853007479	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853007480	TM-ABC transporter signature motif; other site
1133853007481	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1133853007482	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853007483	Walker A/P-loop; other site
1133853007484	ATP binding site [chemical binding]; other site
1133853007485	Q-loop/lid; other site
1133853007486	ABC transporter signature motif; other site
1133853007487	Walker B; other site
1133853007488	D-loop; other site
1133853007489	H-loop/switch region; other site
1133853007490	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853007491	transcriptional regulator LsrR; Provisional; Region: PRK15418
1133853007492	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1133853007493	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1133853007494	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1133853007495	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1133853007496	putative N- and C-terminal domain interface [polypeptide binding]; other site
1133853007497	putative active site [active]
1133853007498	putative MgATP binding site [chemical binding]; other site
1133853007499	catalytic site [active]
1133853007500	metal binding site [ion binding]; metal-binding site
1133853007501	putative carbohydrate binding site [chemical binding]; other site
1133853007502	putative lipoprotein; Provisional; Region: PRK09707
1133853007503	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133853007504	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853007505	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133853007506	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853007507	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133853007508	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853007509	non-specific DNA binding site [nucleotide binding]; other site
1133853007510	salt bridge; other site
1133853007511	sequence-specific DNA binding site [nucleotide binding]; other site
1133853007512	HipA N-terminal domain; Region: Couple_hipA; pfam13657
1133853007513	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1133853007514	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1133853007515	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1133853007516	Helix-turn-helix domain; Region: HTH_18; pfam12833
1133853007517	Fimbrial protein; Region: Fimbrial; cl01416
1133853007518	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1133853007519	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853007520	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853007521	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133853007522	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853007523	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853007524	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853007525	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133853007526	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133853007527	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
1133853007528	mannosyl binding site [chemical binding]; other site
1133853007529	Fimbrial protein; Region: Fimbrial; pfam00419
1133853007530	putative oxidoreductase; Provisional; Region: PRK09939
1133853007531	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1133853007532	putative molybdopterin cofactor binding site [chemical binding]; other site
1133853007533	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1133853007534	putative molybdopterin cofactor binding site; other site
1133853007535	transcriptional regulator YdeO; Provisional; Region: PRK09940
1133853007536	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853007537	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1133853007538	Sulfatase; Region: Sulfatase; cl17466
1133853007539	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853007540	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853007541	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853007542	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1133853007543	Sulfatase; Region: Sulfatase; pfam00884
1133853007544	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1133853007545	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853007546	FeS/SAM binding site; other site
1133853007547	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1133853007548	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1133853007549	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1133853007550	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1133853007551	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1133853007552	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1133853007553	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1133853007554	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1133853007555	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133853007556	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1133853007557	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133853007558	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1133853007559	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853007560	catalytic residue [active]
1133853007561	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
1133853007562	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1133853007563	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1133853007564	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
1133853007565	heme-binding site [chemical binding]; other site
1133853007566	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853007567	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853007568	metal binding site [ion binding]; metal-binding site
1133853007569	active site
1133853007570	I-site; other site
1133853007571	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
1133853007572	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853007573	putative active site [active]
1133853007574	heme pocket [chemical binding]; other site
1133853007575	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853007576	putative active site [active]
1133853007577	heme pocket [chemical binding]; other site
1133853007578	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853007579	metal binding site [ion binding]; metal-binding site
1133853007580	active site
1133853007581	I-site; other site
1133853007582	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853007583	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
1133853007584	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1133853007585	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1133853007586	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1133853007587	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853007588	dimer interface [polypeptide binding]; other site
1133853007589	conserved gate region; other site
1133853007590	putative PBP binding loops; other site
1133853007591	ABC-ATPase subunit interface; other site
1133853007592	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
1133853007593	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133853007594	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853007595	dimer interface [polypeptide binding]; other site
1133853007596	conserved gate region; other site
1133853007597	putative PBP binding loops; other site
1133853007598	ABC-ATPase subunit interface; other site
1133853007599	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1133853007600	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853007601	Walker A/P-loop; other site
1133853007602	ATP binding site [chemical binding]; other site
1133853007603	Q-loop/lid; other site
1133853007604	ABC transporter signature motif; other site
1133853007605	Walker B; other site
1133853007606	D-loop; other site
1133853007607	H-loop/switch region; other site
1133853007608	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1133853007609	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1133853007610	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853007611	Walker A/P-loop; other site
1133853007612	ATP binding site [chemical binding]; other site
1133853007613	Q-loop/lid; other site
1133853007614	ABC transporter signature motif; other site
1133853007615	Walker B; other site
1133853007616	D-loop; other site
1133853007617	H-loop/switch region; other site
1133853007618	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1133853007619	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1133853007620	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
1133853007621	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1133853007622	malate dehydrogenase; Provisional; Region: PRK13529
1133853007623	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1133853007624	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1133853007625	NAD(P) binding site [chemical binding]; other site
1133853007626	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1133853007627	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1133853007628	NAD binding site [chemical binding]; other site
1133853007629	substrate binding site [chemical binding]; other site
1133853007630	catalytic Zn binding site [ion binding]; other site
1133853007631	tetramer interface [polypeptide binding]; other site
1133853007632	structural Zn binding site [ion binding]; other site
1133853007633	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1133853007634	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853007635	non-specific DNA binding site [nucleotide binding]; other site
1133853007636	salt bridge; other site
1133853007637	sequence-specific DNA binding site [nucleotide binding]; other site
1133853007638	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1133853007639	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1133853007640	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1133853007641	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1133853007642	potential frameshift: common BLAST hit: gi|260867914|ref|YP_003234316.1| formate dehydrogenase-N subunit alpha, nitrate-inducible
1133853007643	aromatic amino acid exporter; Provisional; Region: PRK11689
1133853007644	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1133853007645	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1133853007646	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1133853007647	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1133853007648	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1133853007649	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1133853007650	[4Fe-4S] binding site [ion binding]; other site
1133853007651	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853007652	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853007653	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853007654	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1133853007655	molybdopterin cofactor binding site; other site
1133853007656	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1133853007657	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1133853007658	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1133853007659	hypothetical protein; Provisional; Region: PRK10281
1133853007660	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1133853007661	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1133853007662	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
1133853007663	active site 1 [active]
1133853007664	dimer interface [polypeptide binding]; other site
1133853007665	hexamer interface [polypeptide binding]; other site
1133853007666	active site 2 [active]
1133853007667	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133853007668	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853007669	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133853007670	PAAR motif; Region: PAAR_motif; cl15808
1133853007671	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853007672	RHS Repeat; Region: RHS_repeat; pfam05593
1133853007673	RHS Repeat; Region: RHS_repeat; pfam05593
1133853007674	RHS Repeat; Region: RHS_repeat; pfam05593
1133853007675	RHS Repeat; Region: RHS_repeat; pfam05593
1133853007676	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853007677	RHS Repeat; Region: RHS_repeat; pfam05593
1133853007678	RHS Repeat; Region: RHS_repeat; pfam05593
1133853007679	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1133853007680	RHS protein; Region: RHS; pfam03527
1133853007681	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853007682	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133853007683	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133853007684	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133853007685	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1133853007686	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1133853007687	C-terminal domain interface [polypeptide binding]; other site
1133853007688	GSH binding site (G-site) [chemical binding]; other site
1133853007689	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1133853007690	dimer interface [polypeptide binding]; other site
1133853007691	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1133853007692	dimer interface [polypeptide binding]; other site
1133853007693	N-terminal domain interface [polypeptide binding]; other site
1133853007694	substrate binding pocket (H-site) [chemical binding]; other site
1133853007695	L-asparagine permease; Provisional; Region: PRK15049
1133853007696	PQQ-like domain; Region: PQQ_2; pfam13360
1133853007697	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1133853007698	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853007699	N-terminal plug; other site
1133853007700	ligand-binding site [chemical binding]; other site
1133853007701	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1133853007702	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853007703	DNA-binding site [nucleotide binding]; DNA binding site
1133853007704	FCD domain; Region: FCD; pfam07729
1133853007705	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1133853007706	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1133853007707	NAD(P) binding site [chemical binding]; other site
1133853007708	substrate binding site [chemical binding]; other site
1133853007709	dimer interface [polypeptide binding]; other site
1133853007710	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1133853007711	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1133853007712	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1133853007713	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1133853007714	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1133853007715	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1133853007716	trimer interface [polypeptide binding]; other site
1133853007717	active site
1133853007718	substrate binding site [chemical binding]; other site
1133853007719	CoA binding site [chemical binding]; other site
1133853007720	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1133853007721	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1133853007722	tetrameric interface [polypeptide binding]; other site
1133853007723	NAD binding site [chemical binding]; other site
1133853007724	catalytic residues [active]
1133853007725	substrate binding site [chemical binding]; other site
1133853007726	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133853007727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853007728	ABC-ATPase subunit interface; other site
1133853007729	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853007730	dimer interface [polypeptide binding]; other site
1133853007731	conserved gate region; other site
1133853007732	putative PBP binding loops; other site
1133853007733	ABC-ATPase subunit interface; other site
1133853007734	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1133853007735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853007736	Walker A/P-loop; other site
1133853007737	ATP binding site [chemical binding]; other site
1133853007738	Q-loop/lid; other site
1133853007739	ABC transporter signature motif; other site
1133853007740	Walker B; other site
1133853007741	D-loop; other site
1133853007742	H-loop/switch region; other site
1133853007743	TOBE domain; Region: TOBE_2; pfam08402
1133853007744	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1133853007745	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1133853007746	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1133853007747	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853007748	DNA-binding site [nucleotide binding]; DNA binding site
1133853007749	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853007750	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853007751	homodimer interface [polypeptide binding]; other site
1133853007752	catalytic residue [active]
1133853007753	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1133853007754	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853007755	sequence-specific DNA binding site [nucleotide binding]; other site
1133853007756	salt bridge; other site
1133853007757	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1133853007758	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1133853007759	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1133853007760	Peptidase family U32; Region: Peptidase_U32; pfam01136
1133853007761	Collagenase; Region: DUF3656; pfam12392
1133853007762	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133853007763	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853007764	non-specific DNA binding site [nucleotide binding]; other site
1133853007765	salt bridge; other site
1133853007766	sequence-specific DNA binding site [nucleotide binding]; other site
1133853007767	Cupin domain; Region: Cupin_2; pfam07883
1133853007768	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1133853007769	benzoate transporter; Region: benE; TIGR00843
1133853007770	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1133853007771	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1133853007772	Probable transposase; Region: OrfB_IS605; pfam01385
1133853007773	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1133853007774	similar to transposase ORF A (fragment), IS605 family protein; COG1943 Transposase and inactivated derivatives
1133853007775	similar to transposase ORF A (fragment), IS605 family protein; COG1943 Transposase and inactivated derivatives
1133853007776	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1133853007777	tellurite resistance protein TehB; Provisional; Region: PRK11207
1133853007778	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853007779	S-adenosylmethionine binding site [chemical binding]; other site
1133853007780	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1133853007781	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1133853007782	gating phenylalanine in ion channel; other site
1133853007783	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1133853007784	putative trimer interface [polypeptide binding]; other site
1133853007785	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1133853007786	putative CoA binding site [chemical binding]; other site
1133853007787	putative trimer interface [polypeptide binding]; other site
1133853007788	putative CoA binding site [chemical binding]; other site
1133853007789	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1133853007790	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853007791	Coenzyme A binding pocket [chemical binding]; other site
1133853007792	hypothetical protein; Provisional; Region: PRK11415
1133853007793	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1133853007794	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1133853007795	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1133853007796	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1133853007797	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1133853007798	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853007799	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853007800	dimerization interface [polypeptide binding]; other site
1133853007801	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1133853007802	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133853007803	dimer interface [polypeptide binding]; other site
1133853007804	ligand binding site [chemical binding]; other site
1133853007805	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853007806	dimerization interface [polypeptide binding]; other site
1133853007807	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133853007808	dimer interface [polypeptide binding]; other site
1133853007809	putative CheW interface [polypeptide binding]; other site
1133853007810	small toxic polypeptide; Provisional; Region: PRK09738
1133853007811	hypothetical protein; Provisional; Region: PRK10040
1133853007812	cytochrome b561; Provisional; Region: PRK11513
1133853007813	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1133853007814	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1133853007815	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1133853007816	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1133853007817	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1133853007818	NAD binding site [chemical binding]; other site
1133853007819	catalytic residues [active]
1133853007820	substrate binding site [chemical binding]; other site
1133853007821	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1133853007822	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133853007823	putative active site [active]
1133853007824	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1133853007825	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853007826	ATP binding site [chemical binding]; other site
1133853007827	putative Mg++ binding site [ion binding]; other site
1133853007828	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853007829	nucleotide binding region [chemical binding]; other site
1133853007830	ATP-binding site [chemical binding]; other site
1133853007831	Helicase associated domain (HA2); Region: HA2; pfam04408
1133853007832	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1133853007833	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1133853007834	azoreductase; Reviewed; Region: PRK00170
1133853007835	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1133853007836	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1133853007837	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133853007838	active site
1133853007839	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
1133853007840	active site
1133853007841	catalytic residues [active]
1133853007842	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1133853007843	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1133853007844	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853007845	S-adenosylmethionine binding site [chemical binding]; other site
1133853007846	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
1133853007847	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1133853007848	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1133853007849	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1133853007850	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
1133853007851	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853007852	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853007853	active site
1133853007854	catalytic tetrad [active]
1133853007855	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
1133853007856	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1133853007857	putative trimer interface [polypeptide binding]; other site
1133853007858	putative metal binding site [ion binding]; other site
1133853007859	PaaX-like protein; Region: PaaX; pfam07848
1133853007860	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
1133853007861	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1133853007862	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
1133853007863	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1133853007864	active site
1133853007865	AMP binding site [chemical binding]; other site
1133853007866	homodimer interface [polypeptide binding]; other site
1133853007867	acyl-activating enzyme (AAE) consensus motif; other site
1133853007868	CoA binding site [chemical binding]; other site
1133853007869	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1133853007870	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133853007871	dimer interface [polypeptide binding]; other site
1133853007872	active site
1133853007873	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133853007874	CoenzymeA binding site [chemical binding]; other site
1133853007875	subunit interaction site [polypeptide binding]; other site
1133853007876	PHB binding site; other site
1133853007877	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
1133853007878	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1133853007879	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133853007880	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133853007881	enoyl-CoA hydratase; Provisional; Region: PRK08140
1133853007882	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853007883	substrate binding site [chemical binding]; other site
1133853007884	oxyanion hole (OAH) forming residues; other site
1133853007885	trimer interface [polypeptide binding]; other site
1133853007886	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1133853007887	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853007888	substrate binding site [chemical binding]; other site
1133853007889	oxyanion hole (OAH) forming residues; other site
1133853007890	trimer interface [polypeptide binding]; other site
1133853007891	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1133853007892	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1133853007893	FAD binding pocket [chemical binding]; other site
1133853007894	FAD binding motif [chemical binding]; other site
1133853007895	phosphate binding motif [ion binding]; other site
1133853007896	beta-alpha-beta structure motif; other site
1133853007897	NAD(p) ribose binding residues [chemical binding]; other site
1133853007898	NAD binding pocket [chemical binding]; other site
1133853007899	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1133853007900	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853007901	catalytic loop [active]
1133853007902	iron binding site [ion binding]; other site
1133853007903	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1133853007904	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1133853007905	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
1133853007906	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1133853007907	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1133853007908	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1133853007909	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1133853007910	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1133853007911	substrate binding site [chemical binding]; other site
1133853007912	dimer interface [polypeptide binding]; other site
1133853007913	NADP binding site [chemical binding]; other site
1133853007914	catalytic residues [active]
1133853007915	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
1133853007916	substrate binding site [chemical binding]; other site
1133853007917	tyramine oxidase; Provisional; Region: tynA; PRK14696
1133853007918	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1133853007919	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
1133853007920	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
1133853007921	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
1133853007922	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1133853007923	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1133853007924	NAD(P) binding site [chemical binding]; other site
1133853007925	catalytic residues [active]
1133853007926	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
1133853007927	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853007928	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1133853007929	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1133853007930	hypothetical protein; Provisional; Region: PRK10695
1133853007931	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1133853007932	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1133853007933	putative ligand binding site [chemical binding]; other site
1133853007934	putative NAD binding site [chemical binding]; other site
1133853007935	catalytic site [active]
1133853007936	heat-inducible protein; Provisional; Region: PRK10449
1133853007937	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1133853007938	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1133853007939	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1133853007940	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1133853007941	dimer interface [polypeptide binding]; other site
1133853007942	PYR/PP interface [polypeptide binding]; other site
1133853007943	TPP binding site [chemical binding]; other site
1133853007944	substrate binding site [chemical binding]; other site
1133853007945	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1133853007946	Domain of unknown function; Region: EKR; smart00890
1133853007947	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1133853007948	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853007949	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1133853007950	TPP-binding site [chemical binding]; other site
1133853007951	dimer interface [polypeptide binding]; other site
1133853007952	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1133853007953	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133853007954	trimer interface [polypeptide binding]; other site
1133853007955	eyelet of channel; other site
1133853007956	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853007957	Ligand Binding Site [chemical binding]; other site
1133853007958	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1133853007959	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1133853007960	Ligand Binding Site [chemical binding]; other site
1133853007961	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1133853007962	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133853007963	ATP binding site [chemical binding]; other site
1133853007964	Mg++ binding site [ion binding]; other site
1133853007965	motif III; other site
1133853007966	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853007967	nucleotide binding region [chemical binding]; other site
1133853007968	ATP-binding site [chemical binding]; other site
1133853007969	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1133853007970	putative RNA binding site [nucleotide binding]; other site
1133853007971	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1133853007972	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1133853007973	Cl binding site [ion binding]; other site
1133853007974	oligomer interface [polypeptide binding]; other site
1133853007975	PAS domain S-box; Region: sensory_box; TIGR00229
1133853007976	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853007977	putative active site [active]
1133853007978	heme pocket [chemical binding]; other site
1133853007979	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853007980	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853007981	metal binding site [ion binding]; metal-binding site
1133853007982	active site
1133853007983	I-site; other site
1133853007984	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1133853007985	Smr domain; Region: Smr; pfam01713
1133853007986	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1133853007987	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853007988	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1133853007989	putative substrate binding pocket [chemical binding]; other site
1133853007990	putative dimerization interface [polypeptide binding]; other site
1133853007991	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1133853007992	amidohydrolase; Region: amidohydrolases; TIGR01891
1133853007993	putative metal binding site [ion binding]; other site
1133853007994	dimer interface [polypeptide binding]; other site
1133853007995	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1133853007996	amidohydrolase; Region: amidohydrolases; TIGR01891
1133853007997	putative metal binding site [ion binding]; other site
1133853007998	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1133853007999	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1133853008000	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1133853008001	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1133853008002	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1133853008003	DNA binding site [nucleotide binding]
1133853008004	active site
1133853008005	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1133853008006	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1133853008007	ligand binding site [chemical binding]; other site
1133853008008	flexible hinge region; other site
1133853008009	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1133853008010	putative switch regulator; other site
1133853008011	non-specific DNA interactions [nucleotide binding]; other site
1133853008012	DNA binding site [nucleotide binding]
1133853008013	sequence specific DNA binding site [nucleotide binding]; other site
1133853008014	putative cAMP binding site [chemical binding]; other site
1133853008015	universal stress protein UspE; Provisional; Region: PRK11175
1133853008016	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853008017	Ligand Binding Site [chemical binding]; other site
1133853008018	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853008019	Ligand Binding Site [chemical binding]; other site
1133853008020	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1133853008021	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1133853008022	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133853008023	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1133853008024	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1133853008025	peptide binding site [polypeptide binding]; other site
1133853008026	Uncharacterized BCR, COG1636; Region: DUF208; cl17782
1133853008027	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853008028	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853008029	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1133853008030	putative effector binding pocket; other site
1133853008031	putative dimerization interface [polypeptide binding]; other site
1133853008032	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1133853008033	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1133853008034	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133853008035	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1133853008036	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1133853008037	putative active site [active]
1133853008038	Zn binding site [ion binding]; other site
1133853008039	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1133853008040	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1133853008041	active site
1133853008042	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1133853008043	dimer interface [polypeptide binding]; other site
1133853008044	catalytic triad [active]
1133853008045	peroxidatic and resolving cysteines [active]
1133853008046	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1133853008047	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1133853008048	putative aromatic amino acid binding site; other site
1133853008049	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853008050	Walker A motif; other site
1133853008051	ATP binding site [chemical binding]; other site
1133853008052	Walker B motif; other site
1133853008053	arginine finger; other site
1133853008054	Predicted membrane protein [Function unknown]; Region: COG3768
1133853008055	TIGR01620 family protein; Region: hyp_HI0043
1133853008056	Predicted ATPase [General function prediction only]; Region: COG3106
1133853008057	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133853008058	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853008059	DNA binding site [nucleotide binding]
1133853008060	domain linker motif; other site
1133853008061	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1133853008062	putative dimerization interface [polypeptide binding]; other site
1133853008063	putative ligand binding site [chemical binding]; other site
1133853008064	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
1133853008065	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1133853008066	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1133853008067	Walker A/P-loop; other site
1133853008068	ATP binding site [chemical binding]; other site
1133853008069	Q-loop/lid; other site
1133853008070	ABC transporter signature motif; other site
1133853008071	Walker B; other site
1133853008072	D-loop; other site
1133853008073	H-loop/switch region; other site
1133853008074	TOBE domain; Region: TOBE_2; pfam08402
1133853008075	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1133853008076	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853008077	motif II; other site
1133853008078	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1133853008079	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1133853008080	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1133853008081	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1133853008082	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1133853008083	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133853008084	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133853008085	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1133853008086	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853008087	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1133853008088	putative NAD(P) binding site [chemical binding]; other site
1133853008089	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1133853008090	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008091	dimer interface [polypeptide binding]; other site
1133853008092	conserved gate region; other site
1133853008093	putative PBP binding loops; other site
1133853008094	ABC-ATPase subunit interface; other site
1133853008095	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1133853008096	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008097	dimer interface [polypeptide binding]; other site
1133853008098	conserved gate region; other site
1133853008099	putative PBP binding loops; other site
1133853008100	ABC-ATPase subunit interface; other site
1133853008101	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1133853008102	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1133853008103	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1133853008104	sucrose phosphorylase; Provisional; Region: PRK13840
1133853008105	active site
1133853008106	homodimer interface [polypeptide binding]; other site
1133853008107	catalytic site [active]
1133853008108	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1133853008109	active site residue [active]
1133853008110	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1133853008111	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1133853008112	phage shock protein C; Region: phageshock_pspC; TIGR02978
1133853008113	phage shock protein B; Provisional; Region: pspB; PRK09458
1133853008114	phage shock protein PspA; Provisional; Region: PRK10698
1133853008115	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1133853008116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853008117	Walker A motif; other site
1133853008118	ATP binding site [chemical binding]; other site
1133853008119	Walker B motif; other site
1133853008120	arginine finger; other site
1133853008121	4-aminobutyrate transaminase; Provisional; Region: PRK09792
1133853008122	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853008123	inhibitor-cofactor binding pocket; inhibition site
1133853008124	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853008125	catalytic residue [active]
1133853008126	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1133853008127	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1133853008128	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
1133853008129	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
1133853008130	NAD(P) binding site [chemical binding]; other site
1133853008131	catalytic residues [active]
1133853008132	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1133853008133	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853008134	non-specific DNA binding site [nucleotide binding]; other site
1133853008135	salt bridge; other site
1133853008136	sequence-specific DNA binding site [nucleotide binding]; other site
1133853008137	Cupin domain; Region: Cupin_2; pfam07883
1133853008138	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1133853008139	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1133853008140	catalytic triad [active]
1133853008141	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1133853008142	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1133853008143	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1133853008144	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1133853008145	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1133853008146	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1133853008147	peptide binding site [polypeptide binding]; other site
1133853008148	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1133853008149	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008150	dimer interface [polypeptide binding]; other site
1133853008151	conserved gate region; other site
1133853008152	putative PBP binding loops; other site
1133853008153	ABC-ATPase subunit interface; other site
1133853008154	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1133853008155	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133853008156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008157	dimer interface [polypeptide binding]; other site
1133853008158	conserved gate region; other site
1133853008159	putative PBP binding loops; other site
1133853008160	ABC-ATPase subunit interface; other site
1133853008161	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1133853008162	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853008163	Walker A/P-loop; other site
1133853008164	ATP binding site [chemical binding]; other site
1133853008165	Q-loop/lid; other site
1133853008166	ABC transporter signature motif; other site
1133853008167	Walker B; other site
1133853008168	D-loop; other site
1133853008169	H-loop/switch region; other site
1133853008170	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133853008171	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1133853008172	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853008173	Walker A/P-loop; other site
1133853008174	ATP binding site [chemical binding]; other site
1133853008175	Q-loop/lid; other site
1133853008176	ABC transporter signature motif; other site
1133853008177	Walker B; other site
1133853008178	D-loop; other site
1133853008179	H-loop/switch region; other site
1133853008180	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1133853008181	putative active site [active]
1133853008182	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1133853008183	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1133853008184	NAD binding site [chemical binding]; other site
1133853008185	homotetramer interface [polypeptide binding]; other site
1133853008186	homodimer interface [polypeptide binding]; other site
1133853008187	substrate binding site [chemical binding]; other site
1133853008188	active site
1133853008189	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1133853008190	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1133853008191	exoribonuclease II; Provisional; Region: PRK05054
1133853008192	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1133853008193	RNB domain; Region: RNB; pfam00773
1133853008194	S1 RNA binding domain; Region: S1; pfam00575
1133853008195	RNase II stability modulator; Provisional; Region: PRK10060
1133853008196	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853008197	putative active site [active]
1133853008198	heme pocket [chemical binding]; other site
1133853008199	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853008200	metal binding site [ion binding]; metal-binding site
1133853008201	active site
1133853008202	I-site; other site
1133853008203	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853008204	hypothetical protein; Provisional; Region: PRK13658
1133853008205	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133853008206	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133853008207	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853008208	lipoprotein; Provisional; Region: PRK10540
1133853008209	translation initiation factor Sui1; Validated; Region: PRK06824
1133853008210	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1133853008211	putative rRNA binding site [nucleotide binding]; other site
1133853008212	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1133853008213	active site
1133853008214	dimer interface [polypeptide binding]; other site
1133853008215	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1133853008216	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1133853008217	TPR motif; other site
1133853008218	binding surface
1133853008219	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853008220	binding surface
1133853008221	TPR motif; other site
1133853008222	Predicted membrane protein [Function unknown]; Region: COG3771
1133853008223	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133853008224	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1133853008225	active site
1133853008226	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1133853008227	dimerization interface [polypeptide binding]; other site
1133853008228	active site
1133853008229	aconitate hydratase; Validated; Region: PRK09277
1133853008230	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1133853008231	substrate binding site [chemical binding]; other site
1133853008232	ligand binding site [chemical binding]; other site
1133853008233	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1133853008234	substrate binding site [chemical binding]; other site
1133853008235	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1133853008236	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853008237	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1133853008238	substrate binding site [chemical binding]; other site
1133853008239	putative dimerization interface [polypeptide binding]; other site
1133853008240	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1133853008241	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1133853008242	active site
1133853008243	interdomain interaction site; other site
1133853008244	putative metal-binding site [ion binding]; other site
1133853008245	nucleotide binding site [chemical binding]; other site
1133853008246	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1133853008247	domain I; other site
1133853008248	DNA binding groove [nucleotide binding]
1133853008249	phosphate binding site [ion binding]; other site
1133853008250	domain II; other site
1133853008251	domain III; other site
1133853008252	nucleotide binding site [chemical binding]; other site
1133853008253	catalytic site [active]
1133853008254	domain IV; other site
1133853008255	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133853008256	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133853008257	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1133853008258	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1133853008259	hypothetical protein; Provisional; Region: PRK11037
1133853008260	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1133853008261	putative inner membrane peptidase; Provisional; Region: PRK11778
1133853008262	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1133853008263	tandem repeat interface [polypeptide binding]; other site
1133853008264	oligomer interface [polypeptide binding]; other site
1133853008265	active site residues [active]
1133853008266	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1133853008267	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1133853008268	NADP binding site [chemical binding]; other site
1133853008269	homodimer interface [polypeptide binding]; other site
1133853008270	active site
1133853008271	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1133853008272	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
1133853008273	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1133853008274	homodimer interface [polypeptide binding]; other site
1133853008275	Walker A motif; other site
1133853008276	ATP binding site [chemical binding]; other site
1133853008277	hydroxycobalamin binding site [chemical binding]; other site
1133853008278	Walker B motif; other site
1133853008279	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1133853008280	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853008281	RNA binding surface [nucleotide binding]; other site
1133853008282	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1133853008283	probable active site [active]
1133853008284	hypothetical protein; Provisional; Region: PRK11630
1133853008285	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1133853008286	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1133853008287	active site
1133853008288	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1133853008289	anthranilate synthase component I; Provisional; Region: PRK13564
1133853008290	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1133853008291	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1133853008292	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1133853008293	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1133853008294	glutamine binding [chemical binding]; other site
1133853008295	catalytic triad [active]
1133853008296	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1133853008297	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1133853008298	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1133853008299	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1133853008300	active site
1133853008301	ribulose/triose binding site [chemical binding]; other site
1133853008302	phosphate binding site [ion binding]; other site
1133853008303	substrate (anthranilate) binding pocket [chemical binding]; other site
1133853008304	product (indole) binding pocket [chemical binding]; other site
1133853008305	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1133853008306	active site
1133853008307	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1133853008308	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1133853008309	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853008310	catalytic residue [active]
1133853008311	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1133853008312	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1133853008313	substrate binding site [chemical binding]; other site
1133853008314	active site
1133853008315	catalytic residues [active]
1133853008316	heterodimer interface [polypeptide binding]; other site
1133853008317	General stress protein [General function prediction only]; Region: GsiB; COG3729
1133853008318	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1133853008319	dimerization interface [polypeptide binding]; other site
1133853008320	metal binding site [ion binding]; metal-binding site
1133853008321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
1133853008322	OmpW family; Region: OmpW; cl17427
1133853008323	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133853008324	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133853008325	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1133853008326	S-adenosylmethionine binding site [chemical binding]; other site
1133853008327	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133853008328	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133853008329	Phage Tail Collar Domain; Region: Collar; pfam07484
1133853008330	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
1133853008331	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133853008332	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133853008333	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133853008334	Fibronectin type III protein; Region: DUF3672; pfam12421
1133853008335	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133853008336	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133853008337	MPN+ (JAMM) motif; other site
1133853008338	Zinc-binding site [ion binding]; other site
1133853008339	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133853008340	NlpC/P60 family; Region: NLPC_P60; cl17555
1133853008341	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133853008342	Phage-related protein [Function unknown]; Region: COG4718
1133853008343	Phage-related minor tail protein [Function unknown]; Region: COG5281
1133853008344	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133853008345	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1133853008346	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
1133853008347	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1133853008348	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133853008349	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133853008350	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133853008351	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133853008352	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133853008353	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133853008354	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133853008355	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133853008356	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133853008357	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1133853008358	tandem repeat interface [polypeptide binding]; other site
1133853008359	oligomer interface [polypeptide binding]; other site
1133853008360	active site residues [active]
1133853008361	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1133853008362	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1133853008363	gpW; Region: gpW; pfam02831
1133853008364	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133853008365	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1133853008366	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1133853008367	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133853008368	catalytic residues [active]
1133853008369	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
1133853008370	Lysis protein S; Region: Lysis_S; pfam04971
1133853008371	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133853008372	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133853008373	anti-adapter protein IraM; Provisional; Region: PRK09919
1133853008374	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1133853008375	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133853008376	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133853008377	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1133853008378	MarR family; Region: MarR_2; cl17246
1133853008379	Antitermination protein; Region: Antiterm; pfam03589
1133853008380	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1133853008381	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
1133853008382	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1133853008383	Hok/gef family; Region: HOK_GEF; pfam01848
1133853008384	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1133853008385	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1133853008386	Helix-turn-helix domain; Region: HTH_36; pfam13730
1133853008387	primosomal protein DnaI; Provisional; Region: PRK02854
1133853008388	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1133853008389	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853008390	non-specific DNA binding site [nucleotide binding]; other site
1133853008391	salt bridge; other site
1133853008392	transcriptional repressor DicA; Reviewed; Region: PRK09706
1133853008393	sequence-specific DNA binding site [nucleotide binding]; other site
1133853008394	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
1133853008395	DicB protein; Region: DicB; pfam05358
1133853008396	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1133853008397	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1133853008398	active site
1133853008399	catalytic site [active]
1133853008400	substrate binding site [chemical binding]; other site
1133853008401	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1133853008402	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133853008403	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1133853008404	dimer interface [polypeptide binding]; other site
1133853008405	active site
1133853008406	Int/Topo IB signature motif; other site
1133853008407	outer membrane protein W; Provisional; Region: PRK10959
1133853008408	hypothetical protein; Provisional; Region: PRK02868
1133853008409	intracellular septation protein A; Reviewed; Region: PRK00259
1133853008410	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1133853008411	transport protein TonB; Provisional; Region: PRK10819
1133853008412	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1133853008413	YciI-like protein; Reviewed; Region: PRK11370
1133853008414	voltage-gated potassium channel; Provisional; Region: PRK10537
1133853008415	Ion channel; Region: Ion_trans_2; pfam07885
1133853008416	TrkA-N domain; Region: TrkA_N; pfam02254
1133853008417	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1133853008418	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1133853008419	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1133853008420	putative active site [active]
1133853008421	catalytic site [active]
1133853008422	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1133853008423	putative active site [active]
1133853008424	catalytic site [active]
1133853008425	dsDNA-mimic protein; Reviewed; Region: PRK05094
1133853008426	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1133853008427	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853008428	Walker A/P-loop; other site
1133853008429	ATP binding site [chemical binding]; other site
1133853008430	Q-loop/lid; other site
1133853008431	ABC transporter signature motif; other site
1133853008432	Walker B; other site
1133853008433	D-loop; other site
1133853008434	H-loop/switch region; other site
1133853008435	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1133853008436	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1133853008437	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853008438	Walker A/P-loop; other site
1133853008439	ATP binding site [chemical binding]; other site
1133853008440	Q-loop/lid; other site
1133853008441	ABC transporter signature motif; other site
1133853008442	Walker B; other site
1133853008443	D-loop; other site
1133853008444	H-loop/switch region; other site
1133853008445	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1133853008446	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1133853008447	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133853008448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008449	dimer interface [polypeptide binding]; other site
1133853008450	conserved gate region; other site
1133853008451	putative PBP binding loops; other site
1133853008452	ABC-ATPase subunit interface; other site
1133853008453	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1133853008454	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008455	dimer interface [polypeptide binding]; other site
1133853008456	conserved gate region; other site
1133853008457	putative PBP binding loops; other site
1133853008458	ABC-ATPase subunit interface; other site
1133853008459	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1133853008460	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1133853008461	peptide binding site [polypeptide binding]; other site
1133853008462	hypothetical protein; Provisional; Region: PRK11111
1133853008463	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1133853008464	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1133853008465	putative catalytic cysteine [active]
1133853008466	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1133853008467	putative active site [active]
1133853008468	metal binding site [ion binding]; metal-binding site
1133853008469	potential frameshift: common BLAST hit: gi|283784572|ref|YP_003364437.1| ISCro3 transposase
1133853008470	potential frameshift: common BLAST hit: gi|291285848|ref|YP_003502665.1| transposase, IS4 family protein
1133853008471	thymidine kinase; Provisional; Region: PRK04296
1133853008472	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1133853008473	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1133853008474	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1133853008475	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1133853008476	active site
1133853008477	tetramer interface; other site
1133853008478	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853008479	active site
1133853008480	response regulator of RpoS; Provisional; Region: PRK10693
1133853008481	phosphorylation site [posttranslational modification]
1133853008482	intermolecular recognition site; other site
1133853008483	dimerization interface [polypeptide binding]; other site
1133853008484	hypothetical protein; Provisional; Region: PRK10279
1133853008485	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1133853008486	active site
1133853008487	nucleophile elbow; other site
1133853008488	SEC-C motif; Region: SEC-C; pfam02810
1133853008489	hypothetical protein; Provisional; Region: PRK04233
1133853008490	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1133853008491	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1133853008492	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1133853008493	putative active site [active]
1133853008494	putative substrate binding site [chemical binding]; other site
1133853008495	putative cosubstrate binding site; other site
1133853008496	catalytic site [active]
1133853008497	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1133853008498	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1133853008499	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1133853008500	4Fe-4S binding domain; Region: Fer4; cl02805
1133853008501	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1133853008502	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1133853008503	[4Fe-4S] binding site [ion binding]; other site
1133853008504	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853008505	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853008506	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853008507	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1133853008508	molybdopterin cofactor binding site; other site
1133853008509	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1133853008510	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1133853008511	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1133853008512	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853008513	dimerization interface [polypeptide binding]; other site
1133853008514	Histidine kinase; Region: HisKA_3; pfam07730
1133853008515	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853008516	ATP binding site [chemical binding]; other site
1133853008517	Mg2+ binding site [ion binding]; other site
1133853008518	G-X-G motif; other site
1133853008519	transcriptional regulator NarL; Provisional; Region: PRK10651
1133853008520	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853008521	active site
1133853008522	phosphorylation site [posttranslational modification]
1133853008523	intermolecular recognition site; other site
1133853008524	dimerization interface [polypeptide binding]; other site
1133853008525	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853008526	DNA binding residues [nucleotide binding]
1133853008527	dimerization interface [polypeptide binding]; other site
1133853008528	putative invasin; Provisional; Region: PRK10177
1133853008529	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1133853008530	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1133853008531	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
1133853008532	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1133853008533	putative active site pocket [active]
1133853008534	dimerization interface [polypeptide binding]; other site
1133853008535	putative catalytic residue [active]
1133853008536	cation transport regulator; Reviewed; Region: chaB; PRK09582
1133853008537	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1133853008538	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1133853008539	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133853008540	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133853008541	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133853008542	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1133853008543	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1133853008544	hypothetical protein; Provisional; Region: PRK10941
1133853008545	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1133853008546	hypothetical protein; Provisional; Region: PRK10278
1133853008547	HemK family putative methylases; Region: hemK_fam; TIGR00536
1133853008548	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853008549	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1133853008550	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1133853008551	RF-1 domain; Region: RF-1; pfam00472
1133853008552	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1133853008553	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1133853008554	tRNA; other site
1133853008555	putative tRNA binding site [nucleotide binding]; other site
1133853008556	putative NADP binding site [chemical binding]; other site
1133853008557	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1133853008558	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
1133853008559	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1133853008560	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1133853008561	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1133853008562	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1133853008563	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1133853008564	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1133853008565	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853008566	active site
1133853008567	putative transporter; Provisional; Region: PRK11660
1133853008568	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1133853008569	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1133853008570	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1133853008571	hypothetical protein; Provisional; Region: PRK10692
1133853008572	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1133853008573	putative active site [active]
1133853008574	catalytic residue [active]
1133853008575	GTP-binding protein YchF; Reviewed; Region: PRK09601
1133853008576	YchF GTPase; Region: YchF; cd01900
1133853008577	G1 box; other site
1133853008578	GTP/Mg2+ binding site [chemical binding]; other site
1133853008579	Switch I region; other site
1133853008580	G2 box; other site
1133853008581	Switch II region; other site
1133853008582	G3 box; other site
1133853008583	G4 box; other site
1133853008584	G5 box; other site
1133853008585	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1133853008586	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133853008587	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853008588	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853008589	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
1133853008590	PAS domain; Region: PAS; smart00091
1133853008591	putative active site [active]
1133853008592	heme pocket [chemical binding]; other site
1133853008593	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853008594	Walker A motif; other site
1133853008595	ATP binding site [chemical binding]; other site
1133853008596	Walker B motif; other site
1133853008597	arginine finger; other site
1133853008598	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133853008599	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1133853008600	Dak1 domain; Region: Dak1; pfam02733
1133853008601	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1133853008602	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1133853008603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
1133853008604	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133853008605	dimerization domain swap beta strand [polypeptide binding]; other site
1133853008606	regulatory protein interface [polypeptide binding]; other site
1133853008607	active site
1133853008608	regulatory phosphorylation site [posttranslational modification]; other site
1133853008609	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1133853008610	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133853008611	trehalase; Provisional; Region: treA; PRK13271
1133853008612	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1133853008613	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1133853008614	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1133853008615	Flagellar regulator YcgR; Region: YcgR; pfam07317
1133853008616	PilZ domain; Region: PilZ; pfam07238
1133853008617	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1133853008618	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853008619	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853008620	catalytic residue [active]
1133853008621	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1133853008622	dimer interface [polypeptide binding]; other site
1133853008623	catalytic triad [active]
1133853008624	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1133853008625	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1133853008626	TrkA-C domain; Region: TrkA_C; pfam02080
1133853008627	Transporter associated domain; Region: CorC_HlyC; smart01091
1133853008628	alanine racemase; Reviewed; Region: dadX; PRK03646
1133853008629	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1133853008630	active site
1133853008631	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133853008632	substrate binding site [chemical binding]; other site
1133853008633	catalytic residues [active]
1133853008634	dimer interface [polypeptide binding]; other site
1133853008635	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1133853008636	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853008637	SpoVR family protein; Provisional; Region: PRK11767
1133853008638	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1133853008639	fatty acid metabolism regulator; Provisional; Region: PRK04984
1133853008640	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853008641	DNA-binding site [nucleotide binding]; DNA binding site
1133853008642	FadR C-terminal domain; Region: FadR_C; pfam07840
1133853008643	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1133853008644	disulfide bond formation protein B; Provisional; Region: PRK01749
1133853008645	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1133853008646	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1133853008647	active site
1133853008648	DNA binding site [nucleotide binding]
1133853008649	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1133853008650	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1133853008651	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853008652	Catalytic site [active]
1133853008653	potential frameshift: common BLAST hit: gi|209918421|ref|YP_002292505.1| hemolysin E
1133853008654	Haemolysin E (HlyE); Region: HlyE; cl11627
1133853008655	hypothetical protein; Provisional; Region: PRK05170
1133853008656	hypothetical protein; Provisional; Region: PRK10691
1133853008657	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1133853008658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1133853008659	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
1133853008660	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
1133853008661	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
1133853008662	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1133853008663	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1133853008664	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1133853008665	cell division inhibitor MinD; Provisional; Region: PRK10818
1133853008666	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1133853008667	Switch I; other site
1133853008668	Switch II; other site
1133853008669	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1133853008670	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853008671	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133853008672	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853008673	Autotransporter beta-domain; Region: Autotransporter; smart00869
1133853008674	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
1133853008675	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133853008676	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853008677	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1133853008678	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1133853008679	Sensors of blue-light using FAD; Region: BLUF; smart01034
1133853008680	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853008681	transcriptional regulator MirA; Provisional; Region: PRK15043
1133853008682	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1133853008683	DNA binding residues [nucleotide binding]
1133853008684	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
1133853008685	anti-adapter protein IraM; Provisional; Region: PRK09919
1133853008686	isocitrate dehydrogenase; Validated; Region: PRK07362
1133853008687	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1133853008688	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1133853008689	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1133853008690	probable active site [active]
1133853008691	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1133853008692	nudix motif; other site
1133853008693	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1133853008694	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1133853008695	putative lysogenization regulator; Reviewed; Region: PRK00218
1133853008696	adenylosuccinate lyase; Provisional; Region: PRK09285
1133853008697	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1133853008698	tetramer interface [polypeptide binding]; other site
1133853008699	active site
1133853008700	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1133853008701	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853008702	active site
1133853008703	phosphorylation site [posttranslational modification]
1133853008704	intermolecular recognition site; other site
1133853008705	dimerization interface [polypeptide binding]; other site
1133853008706	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853008707	DNA binding site [nucleotide binding]
1133853008708	sensor protein PhoQ; Provisional; Region: PRK10815
1133853008709	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1133853008710	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1133853008711	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1133853008712	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853008713	ATP binding site [chemical binding]; other site
1133853008714	Mg2+ binding site [ion binding]; other site
1133853008715	G-X-G motif; other site
1133853008716	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1133853008717	Cupin-like domain; Region: Cupin_8; pfam13621
1133853008718	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1133853008719	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1133853008720	metal binding site [ion binding]; metal-binding site
1133853008721	dimer interface [polypeptide binding]; other site
1133853008722	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1133853008723	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853008724	Walker A/P-loop; other site
1133853008725	ATP binding site [chemical binding]; other site
1133853008726	Q-loop/lid; other site
1133853008727	ABC transporter signature motif; other site
1133853008728	Walker B; other site
1133853008729	D-loop; other site
1133853008730	H-loop/switch region; other site
1133853008731	TOBE domain; Region: TOBE_2; pfam08402
1133853008732	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133853008733	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008734	dimer interface [polypeptide binding]; other site
1133853008735	conserved gate region; other site
1133853008736	putative PBP binding loops; other site
1133853008737	ABC-ATPase subunit interface; other site
1133853008738	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133853008739	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133853008740	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853008741	Phage Tail Collar Domain; Region: Collar; pfam07484
1133853008742	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
1133853008743	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133853008744	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133853008745	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1133853008746	Interdomain contacts; other site
1133853008747	Cytokine receptor motif; other site
1133853008748	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133853008749	Fibronectin type III protein; Region: DUF3672; pfam12421
1133853008750	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133853008751	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133853008752	MPN+ (JAMM) motif; other site
1133853008753	Zinc-binding site [ion binding]; other site
1133853008754	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133853008755	NlpC/P60 family; Region: NLPC_P60; cl17555
1133853008756	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133853008757	Phage-related protein [Function unknown]; Region: COG4718
1133853008758	Phage-related minor tail protein [Function unknown]; Region: COG5281
1133853008759	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133853008760	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133853008761	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1133853008762	Minor tail protein T; Region: Phage_tail_T; cl05636
1133853008763	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1133853008764	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133853008765	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133853008766	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133853008767	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133853008768	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133853008769	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133853008770	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133853008771	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133853008772	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133853008773	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1133853008774	tandem repeat interface [polypeptide binding]; other site
1133853008775	oligomer interface [polypeptide binding]; other site
1133853008776	active site residues [active]
1133853008777	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1133853008778	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1133853008779	gpW; Region: gpW; pfam02831
1133853008780	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133853008781	Phage DNA packaging protein, Nu1 subunit of terminase [DNA replication, recombination, and repair]; Region: COG4220
1133853008782	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1133853008783	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1133853008784	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133853008785	catalytic residues [active]
1133853008786	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
1133853008787	Lysis protein S; Region: Lysis_S; pfam04971
1133853008788	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133853008789	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133853008790	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853008791	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1133853008792	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133853008793	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1133853008794	Antitermination protein; Region: Antiterm; pfam03589
1133853008795	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1133853008796	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
1133853008797	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1133853008798	Hok/gef family; Region: HOK_GEF; pfam01848
1133853008799	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853008800	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853008801	Methyltransferase domain; Region: Methyltransf_25; pfam13649
1133853008802	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1133853008803	Helix-turn-helix domain; Region: HTH_36; pfam13730
1133853008804	primosomal protein DnaI; Provisional; Region: PRK02854
1133853008805	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1133853008806	similar to putative regulator of the C1 family (possibly fragment); COG1396 Predicted transcriptional regulators
1133853008807	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853008808	non-specific DNA binding site [nucleotide binding]; other site
1133853008809	salt bridge; other site
1133853008810	sequence-specific DNA binding site [nucleotide binding]; other site
1133853008811	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1133853008812	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
1133853008813	DicB protein; Region: DicB; pfam05358
1133853008814	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1133853008815	exonuclease VIII; Reviewed; Region: PRK09709
1133853008816	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1133853008817	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1133853008818	active site
1133853008819	catalytic site [active]
1133853008820	substrate binding site [chemical binding]; other site
1133853008821	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1133853008822	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133853008823	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1133853008824	dimer interface [polypeptide binding]; other site
1133853008825	active site
1133853008826	Int/Topo IB signature motif; other site
1133853008827	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133853008828	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853008829	dimer interface [polypeptide binding]; other site
1133853008830	conserved gate region; other site
1133853008831	putative PBP binding loops; other site
1133853008832	ABC-ATPase subunit interface; other site
1133853008833	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1133853008834	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1133853008835	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1133853008836	Repair protein; Region: Repair_PSII; cl01535
1133853008837	NAD-dependent deacetylase; Provisional; Region: PRK00481
1133853008838	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1133853008839	NAD+ binding site [chemical binding]; other site
1133853008840	substrate binding site [chemical binding]; other site
1133853008841	Zn binding site [ion binding]; other site
1133853008842	fructokinase; Reviewed; Region: PRK09557
1133853008843	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853008844	nucleotide binding site [chemical binding]; other site
1133853008845	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1133853008846	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133853008847	FtsX-like permease family; Region: FtsX; pfam02687
1133853008848	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1133853008849	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133853008850	Walker A/P-loop; other site
1133853008851	ATP binding site [chemical binding]; other site
1133853008852	Q-loop/lid; other site
1133853008853	ABC transporter signature motif; other site
1133853008854	Walker B; other site
1133853008855	D-loop; other site
1133853008856	H-loop/switch region; other site
1133853008857	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1133853008858	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133853008859	FtsX-like permease family; Region: FtsX; pfam02687
1133853008860	Predicted membrane protein [Function unknown]; Region: COG4763
1133853008861	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1133853008862	transcription-repair coupling factor; Provisional; Region: PRK10689
1133853008863	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1133853008864	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853008865	ATP binding site [chemical binding]; other site
1133853008866	putative Mg++ binding site [ion binding]; other site
1133853008867	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853008868	nucleotide binding region [chemical binding]; other site
1133853008869	ATP-binding site [chemical binding]; other site
1133853008870	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1133853008871	L,D-transpeptidase; Provisional; Region: PRK10260
1133853008872	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853008873	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853008874	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853008875	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133853008876	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853008877	hypothetical protein; Provisional; Region: PRK11280
1133853008878	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1133853008879	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853008880	hypothetical protein; Provisional; Region: PRK04940
1133853008881	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1133853008882	beta-hexosaminidase; Provisional; Region: PRK05337
1133853008883	thiamine kinase; Region: ycfN_thiK; TIGR02721
1133853008884	active site
1133853008885	substrate binding site [chemical binding]; other site
1133853008886	ATP binding site [chemical binding]; other site
1133853008887	thiamine kinase; Provisional; Region: thiK; PRK10271
1133853008888	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1133853008889	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1133853008890	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1133853008891	putative dimer interface [polypeptide binding]; other site
1133853008892	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1133853008893	nucleotide binding site/active site [active]
1133853008894	HIT family signature motif; other site
1133853008895	catalytic residue [active]
1133853008896	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1133853008897	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853008898	N-terminal plug; other site
1133853008899	ligand-binding site [chemical binding]; other site
1133853008900	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1133853008901	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133853008902	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853008903	active site turn [active]
1133853008904	phosphorylation site [posttranslational modification]
1133853008905	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1133853008906	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1133853008907	active site
1133853008908	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1133853008909	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1133853008910	thymidylate kinase; Validated; Region: tmk; PRK00698
1133853008911	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1133853008912	TMP-binding site; other site
1133853008913	ATP-binding site [chemical binding]; other site
1133853008914	conserved hypothetical protein, YceG family; Region: TIGR00247
1133853008915	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1133853008916	dimerization interface [polypeptide binding]; other site
1133853008917	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1133853008918	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1133853008919	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853008920	catalytic residue [active]
1133853008921	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1133853008922	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1133853008923	dimer interface [polypeptide binding]; other site
1133853008924	active site
1133853008925	acyl carrier protein; Provisional; Region: acpP; PRK00982
1133853008926	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1133853008927	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1133853008928	NAD(P) binding site [chemical binding]; other site
1133853008929	homotetramer interface [polypeptide binding]; other site
1133853008930	homodimer interface [polypeptide binding]; other site
1133853008931	active site
1133853008932	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1133853008933	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1133853008934	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1133853008935	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1133853008936	dimer interface [polypeptide binding]; other site
1133853008937	active site
1133853008938	CoA binding pocket [chemical binding]; other site
1133853008939	putative phosphate acyltransferase; Provisional; Region: PRK05331
1133853008940	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1133853008941	hypothetical protein; Provisional; Region: PRK11193
1133853008942	Maf-like protein; Region: Maf; pfam02545
1133853008943	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1133853008944	active site
1133853008945	dimer interface [polypeptide binding]; other site
1133853008946	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1133853008947	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853008948	RNA binding surface [nucleotide binding]; other site
1133853008949	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1133853008950	active site
1133853008951	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
1133853008952	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1133853008953	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1133853008954	homodimer interface [polypeptide binding]; other site
1133853008955	oligonucleotide binding site [chemical binding]; other site
1133853008956	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1133853008957	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1133853008958	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1133853008959	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1133853008960	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133853008961	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1133853008962	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1133853008963	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1133853008964	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1133853008965	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1133853008966	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1133853008967	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1133853008968	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1133853008969	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1133853008970	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133853008971	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133853008972	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1133853008973	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133853008974	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1133853008975	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1133853008976	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133853008977	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1133853008978	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133853008979	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1133853008980	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1133853008981	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1133853008982	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1133853008983	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133853008984	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133853008985	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1133853008986	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1133853008987	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
1133853008988	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1133853008989	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1133853008990	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1133853008991	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1133853008992	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1133853008993	MviN-like protein; Region: MVIN; pfam03023
1133853008994	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1133853008995	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133853008996	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133853008997	hypothetical protein; Provisional; Region: PRK11239
1133853008998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1133853008999	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1133853009000	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1133853009001	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1133853009002	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853009003	putative substrate translocation pore; other site
1133853009004	glutaredoxin 2; Provisional; Region: PRK10387
1133853009005	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1133853009006	C-terminal domain interface [polypeptide binding]; other site
1133853009007	GSH binding site (G-site) [chemical binding]; other site
1133853009008	catalytic residues [active]
1133853009009	putative dimer interface [polypeptide binding]; other site
1133853009010	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1133853009011	N-terminal domain interface [polypeptide binding]; other site
1133853009012	lipoprotein; Provisional; Region: PRK10598
1133853009013	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1133853009014	active site
1133853009015	substrate binding pocket [chemical binding]; other site
1133853009016	dimer interface [polypeptide binding]; other site
1133853009017	DNA damage-inducible protein I; Provisional; Region: PRK10597
1133853009018	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1133853009019	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1133853009020	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1133853009021	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1133853009022	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1133853009023	hypothetical protein; Provisional; Region: PRK03757
1133853009024	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1133853009025	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1133853009026	active site residue [active]
1133853009027	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1133853009028	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133853009029	putative acyl-acceptor binding pocket; other site
1133853009030	drug efflux system protein MdtG; Provisional; Region: PRK09874
1133853009031	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853009032	putative substrate translocation pore; other site
1133853009033	secY/secA suppressor protein; Provisional; Region: PRK11467
1133853009034	lipoprotein; Provisional; Region: PRK10175
1133853009035	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1133853009036	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1133853009037	Ligand binding site; other site
1133853009038	DXD motif; other site
1133853009039	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1133853009040	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1133853009041	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1133853009042	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1133853009043	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1133853009044	PLD-like domain; Region: PLDc_2; pfam13091
1133853009045	putative active site [active]
1133853009046	catalytic site [active]
1133853009047	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1133853009048	PLD-like domain; Region: PLDc_2; pfam13091
1133853009049	putative active site [active]
1133853009050	catalytic site [active]
1133853009051	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1133853009052	putative ADP-ribose binding site [chemical binding]; other site
1133853009053	putative active site [active]
1133853009054	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1133853009055	major curlin subunit; Provisional; Region: csgA; PRK10051
1133853009056	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1133853009057	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1133853009058	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1133853009059	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1133853009060	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1133853009061	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1133853009062	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853009063	DNA binding residues [nucleotide binding]
1133853009064	dimerization interface [polypeptide binding]; other site
1133853009065	curli assembly protein CsgE; Provisional; Region: PRK10386
1133853009066	curli assembly protein CsgF; Provisional; Region: PRK10050
1133853009067	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1133853009068	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1133853009069	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1133853009070	putative hydrolase; Validated; Region: PRK09248
1133853009071	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1133853009072	active site
1133853009073	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1133853009074	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1133853009075	putative ligand binding site [chemical binding]; other site
1133853009076	NAD binding site [chemical binding]; other site
1133853009077	dimerization interface [polypeptide binding]; other site
1133853009078	catalytic site [active]
1133853009079	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133853009080	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133853009081	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133853009082	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133853009083	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133853009084	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133853009085	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133853009086	MPN+ (JAMM) motif; other site
1133853009087	Zinc-binding site [ion binding]; other site
1133853009088	Antirestriction protein; Region: Antirestrict; pfam03230
1133853009089	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133853009090	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853009091	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853009092	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853009093	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853009094	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853009095	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853009096	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853009097	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853009098	Transposase; Region: HTH_Tnp_1; pfam01527
1133853009099	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1133853009100	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1133853009101	nucleophile elbow; other site
1133853009102	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1133853009103	YjcZ-like protein; Region: YjcZ; pfam13990
1133853009104	hypothetical protein; Provisional; Region: PRK09866
1133853009105	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133853009106	G1 box; other site
1133853009107	GTP/Mg2+ binding site [chemical binding]; other site
1133853009108	G2 box; other site
1133853009109	Switch I region; other site
1133853009110	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133853009111	G3 box; other site
1133853009112	Switch II region; other site
1133853009113	GTP/Mg2+ binding site [chemical binding]; other site
1133853009114	G4 box; other site
1133853009115	G5 box; other site
1133853009116	potential frameshift: common BLAST hit: gi|260858461|ref|YP_003232352.1| adhesin
1133853009117	potential frameshift: common BLAST hit: gi|260858461|ref|YP_003232352.1| adhesin
1133853009118	Predicted GTPase [General function prediction only]; Region: COG3596
1133853009119	YfjP GTPase; Region: YfjP; cd11383
1133853009120	G1 box; other site
1133853009121	GTP/Mg2+ binding site [chemical binding]; other site
1133853009122	Switch I region; other site
1133853009123	G2 box; other site
1133853009124	Switch II region; other site
1133853009125	G3 box; other site
1133853009126	G4 box; other site
1133853009127	G5 box; other site
1133853009128	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853009129	Transposase; Region: HTH_Tnp_1; pfam01527
1133853009130	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1133853009131	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009132	putative metal binding site [ion binding]; other site
1133853009133	Bacterial stress protein; Region: TerD; pfam02342
1133853009134	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1133853009135	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009136	putative metal binding site [ion binding]; other site
1133853009137	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1133853009138	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009139	putative metal binding site [ion binding]; other site
1133853009140	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1133853009141	tellurite resistance protein terB; Region: terB; cd07176
1133853009142	putative metal binding site [ion binding]; other site
1133853009143	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1133853009144	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009145	putative metal binding site [ion binding]; other site
1133853009146	Uncharacterized protein involved in stress response [General function prediction only]; Region: COG4110
1133853009147	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009148	putative metal binding site [ion binding]; other site
1133853009149	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1133853009150	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009151	putative metal binding site [ion binding]; other site
1133853009152	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
1133853009153	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1133853009154	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853009155	active site
1133853009156	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
1133853009157	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
1133853009158	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
1133853009159	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1133853009160	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
1133853009161	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133853009162	metal ion-dependent adhesion site (MIDAS); other site
1133853009163	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1133853009164	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133853009165	putative metal binding site [ion binding]; other site
1133853009166	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133853009167	metal ion-dependent adhesion site (MIDAS); other site
1133853009168	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133853009169	metal ion-dependent adhesion site (MIDAS); other site
1133853009170	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1133853009171	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1133853009172	substrate binding site [chemical binding]; other site
1133853009173	activation loop (A-loop); other site
1133853009174	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1133853009175	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133853009176	Integrase core domain; Region: rve; pfam00665
1133853009177	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1133853009178	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
1133853009179	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1133853009180	cell density-dependent motility repressor; Provisional; Region: PRK10082
1133853009181	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853009182	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133853009183	dimerization interface [polypeptide binding]; other site
1133853009184	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1133853009185	aspartate racemase; Region: asp_race; TIGR00035
1133853009186	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1133853009187	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1133853009188	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133853009189	Integrase core domain; Region: rve; pfam00665
1133853009190	Integrase core domain; Region: rve_3; pfam13683
1133853009191	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853009192	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853009193	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853009194	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853009195	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853009196	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133853009197	Active Sites [active]
1133853009198	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1133853009199	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1133853009200	Part of AAA domain; Region: AAA_19; pfam13245
1133853009201	AAA domain; Region: AAA_12; pfam13087
1133853009202	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
1133853009203	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1133853009204	CAAX protease self-immunity; Region: Abi; pfam02517
1133853009205	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1133853009206	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
1133853009207	putative active site [active]
1133853009208	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853009209	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1133853009210	Walker A/P-loop; other site
1133853009211	ATP binding site [chemical binding]; other site
1133853009212	Q-loop/lid; other site
1133853009213	ABC transporter signature motif; other site
1133853009214	Walker B; other site
1133853009215	D-loop; other site
1133853009216	H-loop/switch region; other site
1133853009217	HlyD family secretion protein; Region: HlyD; pfam00529
1133853009218	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853009219	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853009220	RTX toxin acyltransferase family; Region: HlyC; pfam02794
1133853009221	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853009222	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853009223	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853009224	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1133853009225	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1133853009226	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1133853009227	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1133853009228	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1133853009229	homodimer interface [polypeptide binding]; other site
1133853009230	TDP-binding site; other site
1133853009231	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1133853009232	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
1133853009233	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
1133853009234	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853009235	N-terminal plug; other site
1133853009236	ligand-binding site [chemical binding]; other site
1133853009237	Transposase; Region: HTH_Tnp_1; pfam01527
1133853009238	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853009239	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853009240	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853009241	potential frameshift: common BLAST hit: gi|218692550|ref|YP_002400762.1| putative transposase ORF 1, IS66 family
1133853009242	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4951
1133853009243	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133853009244	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853009245	ATP binding site [chemical binding]; other site
1133853009246	putative Mg++ binding site [ion binding]; other site
1133853009247	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853009248	nucleotide binding region [chemical binding]; other site
1133853009249	ATP-binding site [chemical binding]; other site
1133853009250	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133853009251	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133853009252	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
1133853009253	integrase; Provisional; Region: PRK09692
1133853009254	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853009255	active site
1133853009256	Int/Topo IB signature motif; other site
1133853009257	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1133853009258	Transposase; Region: HTH_Tnp_1; cl17663
1133853009259	putative transposase OrfB; Reviewed; Region: PHA02517
1133853009260	HTH-like domain; Region: HTH_21; pfam13276
1133853009261	Integrase core domain; Region: rve; pfam00665
1133853009262	Integrase core domain; Region: rve_2; pfam13333
1133853009263	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853009264	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853009265	metal binding site [ion binding]; metal-binding site
1133853009266	active site
1133853009267	I-site; other site
1133853009268	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
1133853009269	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
1133853009270	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
1133853009271	putative active site [active]
1133853009272	putative metal binding site [ion binding]; other site
1133853009273	N-glycosyltransferase; Provisional; Region: PRK11204
1133853009274	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1133853009275	DXD motif; other site
1133853009276	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
1133853009277	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
1133853009278	hypothetical protein; Provisional; Region: PRK10536
1133853009279	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1133853009280	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1133853009281	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1133853009282	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1133853009283	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1133853009284	Imelysin; Region: Peptidase_M75; pfam09375
1133853009285	FTR1 family protein; Region: TIGR00145
1133853009286	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1133853009287	Na binding site [ion binding]; other site
1133853009288	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1133853009289	Predicted transcriptional regulator [Transcription]; Region: COG3905
1133853009290	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1133853009291	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1133853009292	Glutamate binding site [chemical binding]; other site
1133853009293	NAD binding site [chemical binding]; other site
1133853009294	catalytic residues [active]
1133853009295	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1133853009296	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853009297	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1133853009298	pyrimidine utilization protein A; Region: RutA; TIGR03612
1133853009299	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1133853009300	active site
1133853009301	dimer interface [polypeptide binding]; other site
1133853009302	non-prolyl cis peptide bond; other site
1133853009303	insertion regions; other site
1133853009304	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133853009305	Isochorismatase family; Region: Isochorismatase; pfam00857
1133853009306	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1133853009307	catalytic triad [active]
1133853009308	conserved cis-peptide bond; other site
1133853009309	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1133853009310	homotrimer interaction site [polypeptide binding]; other site
1133853009311	putative active site [active]
1133853009312	pyrimidine utilization protein D; Region: RutD; TIGR03611
1133853009313	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1133853009314	putative FMN binding site [chemical binding]; other site
1133853009315	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1133853009316	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1133853009317	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1483
1133853009318	Hok/gef family; Region: HOK_GEF; pfam01848
1133853009319	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133853009320	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133853009321	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133853009322	Phage tail fibre adhesin Gp38; Region: GP38; pfam05268
1133853009323	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133853009324	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133853009325	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133853009326	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853009327	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853009328	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1133853009329	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
1133853009330	large terminase protein; Provisional; Region: 17; PHA02533
1133853009331	large terminase protein; Provisional; Region: 17; PHA02533
1133853009332	Bor protein; Region: Lambda_Bor; pfam06291
1133853009333	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1133853009334	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
1133853009335	ORF11CD3 domain; Region: ORF11CD3; pfam10549
1133853009336	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133853009337	catalytic residues [active]
1133853009338	Lysis protein S; Region: Lysis_S; pfam04971
1133853009339	Protein of unknown function (DUF826); Region: DUF826; pfam05696
1133853009340	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
1133853009341	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133853009342	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133853009343	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133853009344	Shiga-like toxin beta subunit; Region: SLT_beta; pfam02258
1133853009345	Ribosome inactivating protein; Region: RIP; pfam00161
1133853009346	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133853009347	Phage NinH protein; Region: Phage_NinH; pfam06322
1133853009348	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1133853009349	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1133853009350	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1133853009351	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
1133853009352	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1133853009353	active site
1133853009354	metal binding site [ion binding]; metal-binding site
1133853009355	interdomain interaction site; other site
1133853009356	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133853009357	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853009358	ATP binding site [chemical binding]; other site
1133853009359	putative Mg++ binding site [ion binding]; other site
1133853009360	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853009361	nucleotide binding region [chemical binding]; other site
1133853009362	ATP-binding site [chemical binding]; other site
1133853009363	Cro; Region: Cro; pfam09048
1133853009364	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853009365	non-specific DNA binding site [nucleotide binding]; other site
1133853009366	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1133853009367	salt bridge; other site
1133853009368	sequence-specific DNA binding site [nucleotide binding]; other site
1133853009369	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853009370	Catalytic site [active]
1133853009371	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1133853009372	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1133853009373	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
1133853009374	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1133853009375	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1133853009376	RecT family; Region: RecT; pfam03837
1133853009377	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1133853009378	Uncharacterized conserved protein (DUF2303); Region: DUF2303; pfam10065
1133853009379	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853009380	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133853009381	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133853009382	AntA/AntB antirepressor; Region: AntA; pfam08346
1133853009383	Phage anti-repressor protein [Transcription]; Region: COG3561
1133853009384	MT-A70; Region: MT-A70; cl01947
1133853009385	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
1133853009386	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
1133853009387	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133853009388	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1133853009389	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1133853009390	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133853009391	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1133853009392	Int/Topo IB signature motif; other site
1133853009393	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1133853009394	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1133853009395	hypothetical protein; Provisional; Region: PRK10174
1133853009396	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1133853009397	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1133853009398	catalytic core [active]
1133853009399	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1133853009400	hypothetical protein; Provisional; Region: PRK09784
1133853009401	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1133853009402	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133853009403	HSP70 interaction site [polypeptide binding]; other site
1133853009404	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1133853009405	substrate binding site [polypeptide binding]; other site
1133853009406	dimer interface [polypeptide binding]; other site
1133853009407	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1133853009408	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1133853009409	chaperone protein TorD; Validated; Region: torD; PRK04976
1133853009410	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1133853009411	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1133853009412	molybdopterin cofactor binding site [chemical binding]; other site
1133853009413	substrate binding site [chemical binding]; other site
1133853009414	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1133853009415	molybdopterin cofactor binding site; other site
1133853009416	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1133853009417	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1133853009418	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
1133853009419	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853009420	active site
1133853009421	phosphorylation site [posttranslational modification]
1133853009422	intermolecular recognition site; other site
1133853009423	dimerization interface [polypeptide binding]; other site
1133853009424	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853009425	DNA binding site [nucleotide binding]
1133853009426	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
1133853009427	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
1133853009428	putative ligand binding site [chemical binding]; other site
1133853009429	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1133853009430	HAMP domain; Region: HAMP; pfam00672
1133853009431	dimerization interface [polypeptide binding]; other site
1133853009432	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853009433	dimer interface [polypeptide binding]; other site
1133853009434	phosphorylation site [posttranslational modification]
1133853009435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853009436	ATP binding site [chemical binding]; other site
1133853009437	Mg2+ binding site [ion binding]; other site
1133853009438	G-X-G motif; other site
1133853009439	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853009440	active site
1133853009441	phosphorylation site [posttranslational modification]
1133853009442	intermolecular recognition site; other site
1133853009443	dimerization interface [polypeptide binding]; other site
1133853009444	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133853009445	putative binding surface; other site
1133853009446	active site
1133853009447	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1133853009448	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1133853009449	Ferredoxin [Energy production and conversion]; Region: NapF; COG1145
1133853009450	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853009451	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1133853009452	GnsA/GnsB family; Region: GnsAB; pfam08178
1133853009453	cold shock gene; Provisional; Region: PRK09891
1133853009454	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133853009455	DNA-binding site [nucleotide binding]; DNA binding site
1133853009456	RNA-binding motif; other site
1133853009457	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133853009458	DNA-binding site [nucleotide binding]; DNA binding site
1133853009459	RNA-binding motif; other site
1133853009460	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1133853009461	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1133853009462	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1133853009463	polysaccharide export protein Wza; Provisional; Region: PRK15078
1133853009464	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1133853009465	SLBB domain; Region: SLBB; pfam10531
1133853009466	SLBB domain; Region: SLBB; pfam10531
1133853009467	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1133853009468	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1133853009469	active site
1133853009470	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
1133853009471	Chain length determinant protein; Region: Wzz; pfam02706
1133853009472	Chain length determinant protein; Region: Wzz; cl15801
1133853009473	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133853009474	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1133853009475	Nucleotide binding site [chemical binding]; other site
1133853009476	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1133853009477	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1133853009478	catalytic core [active]
1133853009479	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1133853009480	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1133853009481	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1133853009482	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1133853009483	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1133853009484	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1133853009485	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1133853009486	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1133853009487	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1133853009488	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1133853009489	putative substrate-binding site; other site
1133853009490	nickel binding site [ion binding]; other site
1133853009491	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1133853009492	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1133853009493	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1133853009494	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1133853009495	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1133853009496	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133853009497	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1133853009498	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1133853009499	YccA-like proteins; Region: YccA_like; cd10433
1133853009500	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1133853009501	sulfur transfer protein TusE; Provisional; Region: PRK11508
1133853009502	Acylphosphatase; Region: Acylphosphatase; cl00551
1133853009503	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1133853009504	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1133853009505	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1133853009506	putative RNA binding site [nucleotide binding]; other site
1133853009507	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853009508	S-adenosylmethionine binding site [chemical binding]; other site
1133853009509	heat shock protein HspQ; Provisional; Region: PRK14129
1133853009510	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1133853009511	hypothetical protein; Provisional; Region: PRK03641
1133853009512	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1133853009513	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1133853009514	active site
1133853009515	dimer interfaces [polypeptide binding]; other site
1133853009516	catalytic residues [active]
1133853009517	DNA helicase IV; Provisional; Region: helD; PRK11054
1133853009518	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1133853009519	Part of AAA domain; Region: AAA_19; pfam13245
1133853009520	Family description; Region: UvrD_C_2; pfam13538
1133853009521	Predicted membrane protein [Function unknown]; Region: COG3304
1133853009522	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1133853009523	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1133853009524	TIGR01666 family membrane protein; Region: YCCS
1133853009525	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1133853009526	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133853009527	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1133853009528	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1133853009529	cell division inhibitor SulA; Region: sula; TIGR00623
1133853009530	outer membrane protein A; Reviewed; Region: PRK10808
1133853009531	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1133853009532	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133853009533	ligand binding site [chemical binding]; other site
1133853009534	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1133853009535	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1133853009536	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1133853009537	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1133853009538	active site 1 [active]
1133853009539	dimer interface [polypeptide binding]; other site
1133853009540	active site 2 [active]
1133853009541	ribosome modulation factor; Provisional; Region: PRK14563
1133853009542	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1133853009543	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1133853009544	paraquat-inducible protein B; Provisional; Region: PRK10807
1133853009545	mce related protein; Region: MCE; pfam02470
1133853009546	mce related protein; Region: MCE; pfam02470
1133853009547	mce related protein; Region: MCE; pfam02470
1133853009548	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
1133853009549	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1133853009550	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133853009551	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133853009552	ABC transporter ATPase component; Reviewed; Region: PRK11147
1133853009553	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853009554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853009555	Walker A/P-loop; other site
1133853009556	Walker A/P-loop; other site
1133853009557	ATP binding site [chemical binding]; other site
1133853009558	ATP binding site [chemical binding]; other site
1133853009559	Q-loop/lid; other site
1133853009560	Q-loop/lid; other site
1133853009561	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133853009562	ABC transporter signature motif; other site
1133853009563	Walker B; other site
1133853009564	D-loop; other site
1133853009565	ABC transporter; Region: ABC_tran_2; pfam12848
1133853009566	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133853009567	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1133853009568	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1133853009569	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1133853009570	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853009571	S-adenosylmethionine binding site [chemical binding]; other site
1133853009572	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1133853009573	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1133853009574	MOSC domain; Region: MOSC; pfam03473
1133853009575	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853009576	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1133853009577	catalytic loop [active]
1133853009578	iron binding site [ion binding]; other site
1133853009579	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1133853009580	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1133853009581	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1133853009582	quinone interaction residues [chemical binding]; other site
1133853009583	active site
1133853009584	catalytic residues [active]
1133853009585	FMN binding site [chemical binding]; other site
1133853009586	substrate binding site [chemical binding]; other site
1133853009587	putativi pili assembly chaperone; Provisional; Region: PRK11385
1133853009588	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853009589	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853009590	Fimbrial protein; Region: Fimbrial; cl01416
1133853009591	Fimbrial protein; Region: Fimbrial; cl01416
1133853009592	Fimbrial protein; Region: Fimbrial; cl01416
1133853009593	outer membrane usher protein; Provisional; Region: PRK15193
1133853009594	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853009595	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853009596	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853009597	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133853009598	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853009599	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853009600	Fimbrial protein; Region: Fimbrial; cl01416
1133853009601	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1133853009602	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1133853009603	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853009604	substrate binding pocket [chemical binding]; other site
1133853009605	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1133853009606	membrane-bound complex binding site; other site
1133853009607	hinge residues; other site
1133853009608	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1133853009609	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1133853009610	active site
1133853009611	dimer interface [polypeptide binding]; other site
1133853009612	non-prolyl cis peptide bond; other site
1133853009613	insertion regions; other site
1133853009614	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133853009615	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853009616	dimer interface [polypeptide binding]; other site
1133853009617	conserved gate region; other site
1133853009618	putative PBP binding loops; other site
1133853009619	ABC-ATPase subunit interface; other site
1133853009620	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1133853009621	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1133853009622	Walker A/P-loop; other site
1133853009623	ATP binding site [chemical binding]; other site
1133853009624	Q-loop/lid; other site
1133853009625	ABC transporter signature motif; other site
1133853009626	Walker B; other site
1133853009627	D-loop; other site
1133853009628	H-loop/switch region; other site
1133853009629	aminopeptidase N; Provisional; Region: pepN; PRK14015
1133853009630	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1133853009631	active site
1133853009632	Zn binding site [ion binding]; other site
1133853009633	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1133853009634	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1133853009635	active site
1133853009636	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1133853009637	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1133853009638	putative dimer interface [polypeptide binding]; other site
1133853009639	putative anticodon binding site; other site
1133853009640	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1133853009641	homodimer interface [polypeptide binding]; other site
1133853009642	motif 1; other site
1133853009643	motif 2; other site
1133853009644	active site
1133853009645	motif 3; other site
1133853009646	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1133853009647	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133853009648	trimer interface [polypeptide binding]; other site
1133853009649	eyelet of channel; other site
1133853009650	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1133853009651	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853009652	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853009653	homodimer interface [polypeptide binding]; other site
1133853009654	catalytic residue [active]
1133853009655	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853009656	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853009657	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853009658	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853009659	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1133853009660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1133853009661	Peptidase M15; Region: Peptidase_M15_3; cl01194
1133853009662	murein L,D-transpeptidase; Provisional; Region: PRK10594
1133853009663	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1133853009664	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853009665	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853009666	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1133853009667	MukB N-terminal; Region: MukB; pfam04310
1133853009668	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1133853009669	condesin subunit E; Provisional; Region: PRK05256
1133853009670	condesin subunit F; Provisional; Region: PRK05260
1133853009671	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133853009672	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853009673	S-adenosylmethionine binding site [chemical binding]; other site
1133853009674	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1133853009675	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133853009676	putative active site [active]
1133853009677	hypothetical protein; Provisional; Region: PRK10593
1133853009678	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1133853009679	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1133853009680	Ligand binding site; other site
1133853009681	oligomer interface; other site
1133853009682	hypothetical protein; Provisional; Region: PRK11827
1133853009683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1133853009684	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1133853009685	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1133853009686	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1133853009687	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1133853009688	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853009689	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1133853009690	Walker A/P-loop; other site
1133853009691	ATP binding site [chemical binding]; other site
1133853009692	Q-loop/lid; other site
1133853009693	ABC transporter signature motif; other site
1133853009694	Walker B; other site
1133853009695	D-loop; other site
1133853009696	H-loop/switch region; other site
1133853009697	ComEC family competence protein; Provisional; Region: PRK11539
1133853009698	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1133853009699	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
1133853009700	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1133853009701	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1133853009702	IHF dimer interface [polypeptide binding]; other site
1133853009703	IHF - DNA interface [nucleotide binding]; other site
1133853009704	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1133853009705	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1133853009706	RNA binding site [nucleotide binding]; other site
1133853009707	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1133853009708	RNA binding site [nucleotide binding]; other site
1133853009709	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1133853009710	RNA binding site [nucleotide binding]; other site
1133853009711	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1133853009712	RNA binding site [nucleotide binding]; other site
1133853009713	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1133853009714	RNA binding site [nucleotide binding]; other site
1133853009715	cytidylate kinase; Provisional; Region: cmk; PRK00023
1133853009716	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1133853009717	CMP-binding site; other site
1133853009718	The sites determining sugar specificity; other site
1133853009719	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1133853009720	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1133853009721	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1133853009722	hinge; other site
1133853009723	active site
1133853009724	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1133853009725	homodimer interface [polypeptide binding]; other site
1133853009726	substrate-cofactor binding pocket; other site
1133853009727	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853009728	catalytic residue [active]
1133853009729	Predicted membrane protein [Function unknown]; Region: COG2323
1133853009730	uncharacterized domain; Region: TIGR00702
1133853009731	YcaO-like family; Region: YcaO; pfam02624
1133853009732	formate transporter; Provisional; Region: PRK10805
1133853009733	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1133853009734	Pyruvate formate lyase 1; Region: PFL1; cd01678
1133853009735	coenzyme A binding site [chemical binding]; other site
1133853009736	active site
1133853009737	catalytic residues [active]
1133853009738	glycine loop; other site
1133853009739	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1133853009740	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853009741	FeS/SAM binding site; other site
1133853009742	hypothetical protein; Provisional; Region: PRK09739
1133853009743	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1133853009744	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853009745	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853009746	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1133853009747	putative effector binding pocket; other site
1133853009748	putative dimerization interface [polypeptide binding]; other site
1133853009749	Amino acid permease; Region: AA_permease_2; pfam13520
1133853009750	putative MFS family transporter protein; Provisional; Region: PRK03633
1133853009751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853009752	putative substrate translocation pore; other site
1133853009753	Isochorismatase family; Region: Isochorismatase; pfam00857
1133853009754	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1133853009755	catalytic triad [active]
1133853009756	dimer interface [polypeptide binding]; other site
1133853009757	conserved cis-peptide bond; other site
1133853009758	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1133853009759	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1133853009760	4Fe-4S binding domain; Region: Fer4; pfam00037
1133853009761	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1133853009762	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133853009763	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1133853009764	putative [Fe4-S4] binding site [ion binding]; other site
1133853009765	putative molybdopterin cofactor binding site [chemical binding]; other site
1133853009766	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1133853009767	putative molybdopterin cofactor binding site; other site
1133853009768	seryl-tRNA synthetase; Provisional; Region: PRK05431
1133853009769	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1133853009770	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1133853009771	dimer interface [polypeptide binding]; other site
1133853009772	active site
1133853009773	motif 1; other site
1133853009774	motif 2; other site
1133853009775	motif 3; other site
1133853009776	recombination factor protein RarA; Reviewed; Region: PRK13342
1133853009777	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853009778	Walker A motif; other site
1133853009779	ATP binding site [chemical binding]; other site
1133853009780	Walker B motif; other site
1133853009781	arginine finger; other site
1133853009782	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1133853009783	periplasmic chaperone LolA; Region: lolA; TIGR00547
1133853009784	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1133853009785	DNA translocase FtsK; Provisional; Region: PRK10263
1133853009786	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1133853009787	DNA translocase FtsK; Provisional; Region: PRK10263
1133853009788	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1133853009789	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1133853009790	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1133853009791	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853009792	putative DNA binding site [nucleotide binding]; other site
1133853009793	putative Zn2+ binding site [ion binding]; other site
1133853009794	AsnC family; Region: AsnC_trans_reg; pfam01037
1133853009795	thioredoxin reductase; Provisional; Region: PRK10262
1133853009796	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853009797	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853009798	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1133853009799	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853009800	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853009801	Walker A/P-loop; other site
1133853009802	ATP binding site [chemical binding]; other site
1133853009803	Q-loop/lid; other site
1133853009804	ABC transporter signature motif; other site
1133853009805	Walker B; other site
1133853009806	D-loop; other site
1133853009807	H-loop/switch region; other site
1133853009808	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1133853009809	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853009810	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1133853009811	Walker A/P-loop; other site
1133853009812	ATP binding site [chemical binding]; other site
1133853009813	Q-loop/lid; other site
1133853009814	ABC transporter signature motif; other site
1133853009815	Walker B; other site
1133853009816	D-loop; other site
1133853009817	H-loop/switch region; other site
1133853009818	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1133853009819	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1133853009820	rRNA binding site [nucleotide binding]; other site
1133853009821	predicted 30S ribosome binding site; other site
1133853009822	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1133853009823	Clp amino terminal domain; Region: Clp_N; pfam02861
1133853009824	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853009825	Walker A motif; other site
1133853009826	ATP binding site [chemical binding]; other site
1133853009827	Walker B motif; other site
1133853009828	arginine finger; other site
1133853009829	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853009830	Walker A motif; other site
1133853009831	ATP binding site [chemical binding]; other site
1133853009832	Walker B motif; other site
1133853009833	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1133853009834	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1133853009835	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133853009836	DNA-binding site [nucleotide binding]; DNA binding site
1133853009837	RNA-binding motif; other site
1133853009838	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1133853009839	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133853009840	Walker A/P-loop; other site
1133853009841	ATP binding site [chemical binding]; other site
1133853009842	Q-loop/lid; other site
1133853009843	ABC transporter signature motif; other site
1133853009844	Walker B; other site
1133853009845	D-loop; other site
1133853009846	H-loop/switch region; other site
1133853009847	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133853009848	FtsX-like permease family; Region: FtsX; pfam02687
1133853009849	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1133853009850	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853009851	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853009852	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1133853009853	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1133853009854	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1133853009855	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1133853009856	putative active site [active]
1133853009857	putative metal-binding site [ion binding]; other site
1133853009858	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1133853009859	amphipathic channel; other site
1133853009860	Asn-Pro-Ala signature motifs; other site
1133853009861	Predicted membrane protein [Function unknown]; Region: COG2431
1133853009862	hybrid cluster protein; Provisional; Region: PRK05290
1133853009863	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853009864	ACS interaction site; other site
1133853009865	CODH interaction site; other site
1133853009866	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1133853009867	hybrid metal cluster; other site
1133853009868	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1133853009869	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1133853009870	FAD binding pocket [chemical binding]; other site
1133853009871	FAD binding motif [chemical binding]; other site
1133853009872	phosphate binding motif [ion binding]; other site
1133853009873	beta-alpha-beta structure motif; other site
1133853009874	NAD binding pocket [chemical binding]; other site
1133853009875	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853009876	catalytic loop [active]
1133853009877	iron binding site [ion binding]; other site
1133853009878	pyruvate dehydrogenase; Provisional; Region: PRK09124
1133853009879	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1133853009880	PYR/PP interface [polypeptide binding]; other site
1133853009881	dimer interface [polypeptide binding]; other site
1133853009882	tetramer interface [polypeptide binding]; other site
1133853009883	TPP binding site [chemical binding]; other site
1133853009884	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133853009885	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1133853009886	TPP-binding site [chemical binding]; other site
1133853009887	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1133853009888	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1133853009889	tetramer interface [polypeptide binding]; other site
1133853009890	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853009891	catalytic residue [active]
1133853009892	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1133853009893	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1133853009894	putative NAD(P) binding site [chemical binding]; other site
1133853009895	putative active site [active]
1133853009896	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1133853009897	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133853009898	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133853009899	NAD(P) binding site [chemical binding]; other site
1133853009900	active site
1133853009901	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1133853009902	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1133853009903	amidase catalytic site [active]
1133853009904	Zn binding residues [ion binding]; other site
1133853009905	substrate binding site [chemical binding]; other site
1133853009906	hypothetical protein; Provisional; Region: PRK02877
1133853009907	putative lipoprotein; Provisional; Region: PRK10533
1133853009908	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1133853009909	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853009910	Walker A/P-loop; other site
1133853009911	ATP binding site [chemical binding]; other site
1133853009912	Q-loop/lid; other site
1133853009913	ABC transporter signature motif; other site
1133853009914	Walker B; other site
1133853009915	D-loop; other site
1133853009916	H-loop/switch region; other site
1133853009917	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1133853009918	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853009919	substrate binding pocket [chemical binding]; other site
1133853009920	membrane-bound complex binding site; other site
1133853009921	hinge residues; other site
1133853009922	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853009923	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853009924	dimer interface [polypeptide binding]; other site
1133853009925	conserved gate region; other site
1133853009926	putative PBP binding loops; other site
1133853009927	ABC-ATPase subunit interface; other site
1133853009928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853009929	dimer interface [polypeptide binding]; other site
1133853009930	conserved gate region; other site
1133853009931	putative PBP binding loops; other site
1133853009932	ABC-ATPase subunit interface; other site
1133853009933	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1133853009934	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853009935	substrate binding pocket [chemical binding]; other site
1133853009936	membrane-bound complex binding site; other site
1133853009937	hinge residues; other site
1133853009938	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1133853009939	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853009940	S-adenosylmethionine binding site [chemical binding]; other site
1133853009941	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1133853009942	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133853009943	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853009944	dimer interface [polypeptide binding]; other site
1133853009945	conserved gate region; other site
1133853009946	putative PBP binding loops; other site
1133853009947	ABC-ATPase subunit interface; other site
1133853009948	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1133853009949	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853009950	dimer interface [polypeptide binding]; other site
1133853009951	conserved gate region; other site
1133853009952	putative PBP binding loops; other site
1133853009953	ABC-ATPase subunit interface; other site
1133853009954	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1133853009955	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853009956	Walker A/P-loop; other site
1133853009957	ATP binding site [chemical binding]; other site
1133853009958	Q-loop/lid; other site
1133853009959	ABC transporter signature motif; other site
1133853009960	Walker B; other site
1133853009961	D-loop; other site
1133853009962	H-loop/switch region; other site
1133853009963	TOBE domain; Region: TOBE_2; pfam08402
1133853009964	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1133853009965	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1133853009966	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1133853009967	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1133853009968	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1133853009969	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1133853009970	dimer interface [polypeptide binding]; other site
1133853009971	FMN binding site [chemical binding]; other site
1133853009972	NADPH bind site [chemical binding]; other site
1133853009973	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1133853009974	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1133853009975	GSH binding site [chemical binding]; other site
1133853009976	catalytic residues [active]
1133853009977	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1133853009978	putative transporter; Provisional; Region: PRK04972
1133853009979	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1133853009980	TrkA-C domain; Region: TrkA_C; pfam02080
1133853009981	TrkA-C domain; Region: TrkA_C; pfam02080
1133853009982	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1133853009983	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1133853009984	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853009985	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1133853009986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853009987	putative substrate translocation pore; other site
1133853009988	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853009989	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1133853009990	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853009991	active site
1133853009992	motif I; other site
1133853009993	motif II; other site
1133853009994	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853009995	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1133853009996	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1133853009997	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853009998	putative substrate translocation pore; other site
1133853009999	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1133853010000	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133853010001	active site
1133853010002	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1133853010003	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853010004	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853010005	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1133853010006	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1133853010007	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1133853010008	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1133853010009	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1133853010010	putative C-terminal domain interface [polypeptide binding]; other site
1133853010011	putative GSH binding site (G-site) [chemical binding]; other site
1133853010012	putative dimer interface [polypeptide binding]; other site
1133853010013	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1133853010014	N-terminal domain interface [polypeptide binding]; other site
1133853010015	dimer interface [polypeptide binding]; other site
1133853010016	substrate binding pocket (H-site) [chemical binding]; other site
1133853010017	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1133853010018	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1133853010019	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1133853010020	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1133853010021	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1133853010022	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853010023	FeS/SAM binding site; other site
1133853010024	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853010025	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853010026	metal binding site [ion binding]; metal-binding site
1133853010027	active site
1133853010028	I-site; other site
1133853010029	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853010030	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1133853010031	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133853010032	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853010033	dimer interface [polypeptide binding]; other site
1133853010034	conserved gate region; other site
1133853010035	putative PBP binding loops; other site
1133853010036	ABC-ATPase subunit interface; other site
1133853010037	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1133853010038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853010039	dimer interface [polypeptide binding]; other site
1133853010040	conserved gate region; other site
1133853010041	putative PBP binding loops; other site
1133853010042	ABC-ATPase subunit interface; other site
1133853010043	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1133853010044	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1133853010045	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1133853010046	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853010047	Walker A/P-loop; other site
1133853010048	ATP binding site [chemical binding]; other site
1133853010049	Q-loop/lid; other site
1133853010050	ABC transporter signature motif; other site
1133853010051	Walker B; other site
1133853010052	D-loop; other site
1133853010053	H-loop/switch region; other site
1133853010054	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133853010055	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853010056	Walker A/P-loop; other site
1133853010057	ATP binding site [chemical binding]; other site
1133853010058	Q-loop/lid; other site
1133853010059	ABC transporter signature motif; other site
1133853010060	Walker B; other site
1133853010061	D-loop; other site
1133853010062	H-loop/switch region; other site
1133853010063	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1133853010064	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1133853010065	catalytic nucleophile [active]
1133853010066	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1133853010067	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1133853010068	dimer interface [polypeptide binding]; other site
1133853010069	putative functional site; other site
1133853010070	putative MPT binding site; other site
1133853010071	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1133853010072	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1133853010073	ATP binding site [chemical binding]; other site
1133853010074	substrate interface [chemical binding]; other site
1133853010075	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1133853010076	active site
1133853010077	intersubunit interactions; other site
1133853010078	catalytic residue [active]
1133853010079	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1133853010080	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1133853010081	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1133853010082	dimer interface [polypeptide binding]; other site
1133853010083	active site
1133853010084	glycine loop; other site
1133853010085	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1133853010086	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853010087	active site
1133853010088	motif I; other site
1133853010089	motif II; other site
1133853010090	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853010091	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1133853010092	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853010093	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853010094	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853010095	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1133853010096	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853010097	Walker A/P-loop; other site
1133853010098	ATP binding site [chemical binding]; other site
1133853010099	Q-loop/lid; other site
1133853010100	ABC transporter signature motif; other site
1133853010101	Walker B; other site
1133853010102	D-loop; other site
1133853010103	H-loop/switch region; other site
1133853010104	ABC transporter; Region: ABC_tran_2; pfam12848
1133853010105	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133853010106	L,D-transpeptidase; Provisional; Region: PRK10260
1133853010107	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853010108	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133853010109	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1133853010110	transmembrane helices; other site
1133853010111	manganese transport regulator MntR; Provisional; Region: PRK11050
1133853010112	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1133853010113	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1133853010114	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1133853010115	Sulfatase; Region: Sulfatase; pfam00884
1133853010116	outer membrane protein X; Provisional; Region: ompX; PRK09408
1133853010117	threonine and homoserine efflux system; Provisional; Region: PRK10532
1133853010118	EamA-like transporter family; Region: EamA; pfam00892
1133853010119	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1133853010120	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1133853010121	dimerization interface [polypeptide binding]; other site
1133853010122	DPS ferroxidase diiron center [ion binding]; other site
1133853010123	ion pore; other site
1133853010124	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1133853010125	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853010126	substrate binding pocket [chemical binding]; other site
1133853010127	membrane-bound complex binding site; other site
1133853010128	hinge residues; other site
1133853010129	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853010130	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853010131	dimer interface [polypeptide binding]; other site
1133853010132	conserved gate region; other site
1133853010133	putative PBP binding loops; other site
1133853010134	ABC-ATPase subunit interface; other site
1133853010135	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1133853010136	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133853010137	Walker A/P-loop; other site
1133853010138	ATP binding site [chemical binding]; other site
1133853010139	Q-loop/lid; other site
1133853010140	ABC transporter signature motif; other site
1133853010141	Walker B; other site
1133853010142	D-loop; other site
1133853010143	H-loop/switch region; other site
1133853010144	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1133853010145	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133853010146	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1133853010147	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1133853010148	hypothetical protein; Provisional; Region: PRK10259
1133853010149	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
1133853010150	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853010151	N-terminal plug; other site
1133853010152	ligand-binding site [chemical binding]; other site
1133853010153	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
1133853010154	hypothetical protein; Provisional; Region: PRK11019
1133853010155	hypothetical protein; Provisional; Region: PRK10259
1133853010156	putative dehydrogenase; Provisional; Region: PRK10098
1133853010157	glycosyl transferase family protein; Provisional; Region: PRK08136
1133853010158	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1133853010159	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1133853010160	DEAD_2; Region: DEAD_2; pfam06733
1133853010161	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1133853010162	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
1133853010163	helicase 45; Provisional; Region: PTZ00424
1133853010164	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133853010165	ATP binding site [chemical binding]; other site
1133853010166	Mg++ binding site [ion binding]; other site
1133853010167	motif III; other site
1133853010168	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853010169	nucleotide binding region [chemical binding]; other site
1133853010170	ATP-binding site [chemical binding]; other site
1133853010171	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1133853010172	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1133853010173	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1133853010174	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853010175	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853010176	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1133853010177	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133853010178	Walker A/P-loop; other site
1133853010179	ATP binding site [chemical binding]; other site
1133853010180	Q-loop/lid; other site
1133853010181	ABC transporter signature motif; other site
1133853010182	Walker B; other site
1133853010183	D-loop; other site
1133853010184	H-loop/switch region; other site
1133853010185	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1133853010186	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133853010187	Walker A/P-loop; other site
1133853010188	ATP binding site [chemical binding]; other site
1133853010189	Q-loop/lid; other site
1133853010190	ABC transporter signature motif; other site
1133853010191	Walker B; other site
1133853010192	D-loop; other site
1133853010193	H-loop/switch region; other site
1133853010194	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133853010195	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1133853010196	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133853010197	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1133853010198	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1133853010199	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1133853010200	putative catalytic site [active]
1133853010201	putative metal binding site [ion binding]; other site
1133853010202	putative phosphate binding site [ion binding]; other site
1133853010203	cardiolipin synthase 2; Provisional; Region: PRK11263
1133853010204	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1133853010205	putative active site [active]
1133853010206	catalytic site [active]
1133853010207	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1133853010208	putative active site [active]
1133853010209	catalytic site [active]
1133853010210	Predicted integral membrane protein [Function unknown]; Region: COG0392
1133853010211	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1133853010212	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1133853010213	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1133853010214	BAX inhibitor (BI)-1/YccA-like protein family; Region: BI-1-like; cl00473
1133853010215	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1133853010216	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1133853010217	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1133853010218	MoaE homodimer interface [polypeptide binding]; other site
1133853010219	MoaD interaction [polypeptide binding]; other site
1133853010220	active site residues [active]
1133853010221	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1133853010222	MoaE interaction surface [polypeptide binding]; other site
1133853010223	MoeB interaction surface [polypeptide binding]; other site
1133853010224	thiocarboxylated glycine; other site
1133853010225	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1133853010226	trimer interface [polypeptide binding]; other site
1133853010227	dimer interface [polypeptide binding]; other site
1133853010228	putative active site [active]
1133853010229	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1133853010230	MPT binding site; other site
1133853010231	trimer interface [polypeptide binding]; other site
1133853010232	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1133853010233	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853010234	FeS/SAM binding site; other site
1133853010235	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1133853010236	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1133853010237	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1133853010238	putative substrate binding pocket [chemical binding]; other site
1133853010239	dimer interface [polypeptide binding]; other site
1133853010240	phosphate binding site [ion binding]; other site
1133853010241	excinuclease ABC subunit B; Provisional; Region: PRK05298
1133853010242	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853010243	ATP binding site [chemical binding]; other site
1133853010244	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853010245	nucleotide binding region [chemical binding]; other site
1133853010246	ATP-binding site [chemical binding]; other site
1133853010247	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1133853010248	UvrB/uvrC motif; Region: UVR; pfam02151
1133853010249	AAA domain; Region: AAA_26; pfam13500
1133853010250	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1133853010251	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
1133853010252	ADP binding site [chemical binding]; other site
1133853010253	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1133853010254	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853010255	S-adenosylmethionine binding site [chemical binding]; other site
1133853010256	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1133853010257	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1133853010258	substrate-cofactor binding pocket; other site
1133853010259	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853010260	catalytic residue [active]
1133853010261	biotin synthase; Provisional; Region: PRK15108
1133853010262	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853010263	FeS/SAM binding site; other site
1133853010264	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1133853010265	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1133853010266	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853010267	inhibitor-cofactor binding pocket; inhibition site
1133853010268	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853010269	catalytic residue [active]
1133853010270	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1133853010271	substrate binding site [chemical binding]; other site
1133853010272	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1133853010273	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853010274	metal binding site [ion binding]; metal-binding site
1133853010275	active site
1133853010276	I-site; other site
1133853010277	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133853010278	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853010279	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133853010280	Phage Tail Collar Domain; Region: Collar; pfam07484
1133853010281	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133853010282	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133853010283	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133853010284	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133853010285	Fibronectin type III protein; Region: DUF3672; pfam12421
1133853010286	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133853010287	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133853010288	MPN+ (JAMM) motif; other site
1133853010289	Zinc-binding site [ion binding]; other site
1133853010290	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133853010291	NlpC/P60 family; Region: NLPC_P60; cl17555
1133853010292	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133853010293	Phage-related protein [Function unknown]; Region: COG4718
1133853010294	Phage-related minor tail protein [Function unknown]; Region: COG5281
1133853010295	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133853010296	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1133853010297	Minor tail protein T; Region: Phage_tail_T; pfam06223
1133853010298	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1133853010299	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133853010300	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133853010301	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133853010302	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133853010303	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133853010304	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133853010305	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133853010306	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133853010307	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133853010308	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1133853010309	tandem repeat interface [polypeptide binding]; other site
1133853010310	oligomer interface [polypeptide binding]; other site
1133853010311	active site residues [active]
1133853010312	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1133853010313	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1133853010314	gpW; Region: gpW; pfam02831
1133853010315	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133853010316	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
1133853010317	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1133853010318	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1133853010319	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
1133853010320	KilA-N domain; Region: KilA-N; pfam04383
1133853010321	ORF11CD3 domain; Region: ORF11CD3; pfam10549
1133853010322	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1133853010323	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133853010324	catalytic residues [active]
1133853010325	Lysis protein S; Region: Lysis_S; pfam04971
1133853010326	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1133853010327	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133853010328	trimer interface [polypeptide binding]; other site
1133853010329	eyelet of channel; other site
1133853010330	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133853010331	Endodeoxyribonuclease RusA; Region: RusA; cl01885
1133853010332	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1133853010333	prophage protein NinE; Provisional; Region: PRK09689
1133853010334	hypothetical protein; Provisional; Region: PRK09741
1133853010335	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1133853010336	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1133853010337	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1133853010338	Replication protein P; Region: Phage_lambda_P; pfam06992
1133853010339	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1133853010340	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1133853010341	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1133853010342	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853010343	non-specific DNA binding site [nucleotide binding]; other site
1133853010344	salt bridge; other site
1133853010345	Predicted transcriptional regulator [Transcription]; Region: COG2932
1133853010346	sequence-specific DNA binding site [nucleotide binding]; other site
1133853010347	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853010348	Catalytic site [active]
1133853010349	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1133853010350	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
1133853010351	phage recombination protein Bet; Region: bet_lambda; TIGR01913
1133853010352	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1133853010353	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
1133853010354	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
1133853010355	DksA-like zinc finger domain containing protein; Region: PHA00080
1133853010356	Excisionase-like protein; Region: Exc; pfam07825
1133853010357	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1133853010358	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
1133853010359	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1133853010360	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1133853010361	dimer interface [polypeptide binding]; other site
1133853010362	active site
1133853010363	Int/Topo IB signature motif; other site
1133853010364	acyl-CoA thioesterase; Provisional; Region: PRK10531
1133853010365	putative pectinesterase; Region: PLN02432; cl01911
1133853010366	putative hydratase; Provisional; Region: PRK11413
1133853010367	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1133853010368	substrate binding site [chemical binding]; other site
1133853010369	ligand binding site [chemical binding]; other site
1133853010370	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1133853010371	substrate binding site [chemical binding]; other site
1133853010372	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133853010373	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1133853010374	transmembrane helices; other site
1133853010375	PrpF protein; Region: PrpF; pfam04303
1133853010376	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853010377	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853010378	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1133853010379	putative dimerization interface [polypeptide binding]; other site
1133853010380	6-phosphogluconolactonase; Provisional; Region: PRK11028
1133853010381	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1133853010382	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853010383	motif II; other site
1133853010384	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853010385	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1133853010386	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853010387	Walker A/P-loop; other site
1133853010388	ATP binding site [chemical binding]; other site
1133853010389	Q-loop/lid; other site
1133853010390	ABC transporter signature motif; other site
1133853010391	Walker B; other site
1133853010392	D-loop; other site
1133853010393	H-loop/switch region; other site
1133853010394	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1133853010395	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1133853010396	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853010397	putative PBP binding loops; other site
1133853010398	ABC-ATPase subunit interface; other site
1133853010399	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1133853010400	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853010401	substrate binding pocket [chemical binding]; other site
1133853010402	membrane-bound complex binding site; other site
1133853010403	hinge residues; other site
1133853010404	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1133853010405	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1133853010406	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1133853010407	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1133853010408	TOBE domain; Region: TOBE; pfam03459
1133853010409	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1133853010410	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1133853010411	Walker A/P-loop; other site
1133853010412	ATP binding site [chemical binding]; other site
1133853010413	Q-loop/lid; other site
1133853010414	ABC transporter signature motif; other site
1133853010415	Walker B; other site
1133853010416	D-loop; other site
1133853010417	H-loop/switch region; other site
1133853010418	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853010419	Walker A/P-loop; other site
1133853010420	ATP binding site [chemical binding]; other site
1133853010421	Q-loop/lid; other site
1133853010422	ABC transporter signature motif; other site
1133853010423	Walker B; other site
1133853010424	D-loop; other site
1133853010425	H-loop/switch region; other site
1133853010426	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1133853010427	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1133853010428	NAD binding site [chemical binding]; other site
1133853010429	homodimer interface [polypeptide binding]; other site
1133853010430	active site
1133853010431	substrate binding site [chemical binding]; other site
1133853010432	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1133853010433	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1133853010434	dimer interface [polypeptide binding]; other site
1133853010435	active site
1133853010436	galactokinase; Provisional; Region: PRK05101
1133853010437	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1133853010438	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1133853010439	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1133853010440	active site
1133853010441	catalytic residues [active]
1133853010442	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133853010443	catalytic core [active]
1133853010444	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133853010445	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1133853010446	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1133853010447	YbgS-like protein; Region: YbgS; pfam13985
1133853010448	zinc transporter ZitB; Provisional; Region: PRK03557
1133853010449	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1133853010450	quinolinate synthetase; Provisional; Region: PRK09375
1133853010451	tol-pal system protein YbgF; Provisional; Region: PRK10803
1133853010452	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1133853010453	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1133853010454	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1133853010455	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133853010456	ligand binding site [chemical binding]; other site
1133853010457	translocation protein TolB; Provisional; Region: tolB; PRK03629
1133853010458	TolB amino-terminal domain; Region: TolB_N; pfam04052
1133853010459	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1133853010460	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1133853010461	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1133853010462	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1133853010463	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1133853010464	TolA C-terminal; Region: TolA; pfam06519
1133853010465	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1133853010466	colicin uptake protein TolR; Provisional; Region: PRK11024
1133853010467	colicin uptake protein TolQ; Provisional; Region: PRK10801
1133853010468	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1133853010469	active site
1133853010470	hypothetical protein; Provisional; Region: PRK10588
1133853010471	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1133853010472	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1133853010473	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1133853010474	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1133853010475	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1133853010476	alpha-mannosidase; Provisional; Region: PRK09819
1133853010477	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1133853010478	active site
1133853010479	metal binding site [ion binding]; metal-binding site
1133853010480	catalytic site [active]
1133853010481	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1133853010482	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1133853010483	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853010484	active site
1133853010485	phosphorylation site [posttranslational modification]
1133853010486	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133853010487	active site
1133853010488	P-loop; other site
1133853010489	phosphorylation site [posttranslational modification]
1133853010490	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1133853010491	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
1133853010492	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853010493	DNA-binding site [nucleotide binding]; DNA binding site
1133853010494	UTRA domain; Region: UTRA; pfam07702
1133853010495	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1133853010496	CoA binding domain; Region: CoA_binding; smart00881
1133853010497	CoA-ligase; Region: Ligase_CoA; pfam00549
1133853010498	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1133853010499	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1133853010500	CoA-ligase; Region: Ligase_CoA; pfam00549
1133853010501	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1133853010502	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133853010503	E3 interaction surface; other site
1133853010504	lipoyl attachment site [posttranslational modification]; other site
1133853010505	e3 binding domain; Region: E3_binding; pfam02817
1133853010506	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1133853010507	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1133853010508	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1133853010509	TPP-binding site [chemical binding]; other site
1133853010510	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1133853010511	dimer interface [polypeptide binding]; other site
1133853010512	PYR/PP interface [polypeptide binding]; other site
1133853010513	TPP binding site [chemical binding]; other site
1133853010514	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1133853010515	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1133853010516	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1133853010517	L-aspartate oxidase; Provisional; Region: PRK06175
1133853010518	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1133853010519	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1133853010520	SdhC subunit interface [polypeptide binding]; other site
1133853010521	proximal heme binding site [chemical binding]; other site
1133853010522	cardiolipin binding site; other site
1133853010523	Iron-sulfur protein interface; other site
1133853010524	proximal quinone binding site [chemical binding]; other site
1133853010525	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1133853010526	Iron-sulfur protein interface; other site
1133853010527	proximal quinone binding site [chemical binding]; other site
1133853010528	SdhD (CybS) interface [polypeptide binding]; other site
1133853010529	proximal heme binding site [chemical binding]; other site
1133853010530	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1133853010531	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1133853010532	dimer interface [polypeptide binding]; other site
1133853010533	active site
1133853010534	citrylCoA binding site [chemical binding]; other site
1133853010535	NADH binding [chemical binding]; other site
1133853010536	cationic pore residues; other site
1133853010537	oxalacetate/citrate binding site [chemical binding]; other site
1133853010538	coenzyme A binding site [chemical binding]; other site
1133853010539	catalytic triad [active]
1133853010540	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133853010541	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853010542	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853010543	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853010544	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853010545	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853010546	Fimbrial protein; Region: Fimbrial; pfam00419
1133853010547	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1133853010548	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1133853010549	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1133853010550	endonuclease VIII; Provisional; Region: PRK10445
1133853010551	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1133853010552	DNA binding site [nucleotide binding]
1133853010553	catalytic residue [active]
1133853010554	putative catalytic residues [active]
1133853010555	H2TH interface [polypeptide binding]; other site
1133853010556	intercalation triad [nucleotide binding]; other site
1133853010557	substrate specificity determining residue; other site
1133853010558	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1133853010559	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1133853010560	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1133853010561	putative active site [active]
1133853010562	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
1133853010563	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1133853010564	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
1133853010565	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1133853010566	metal-binding protein; Provisional; Region: PRK10799
1133853010567	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133853010568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853010569	putative substrate translocation pore; other site
1133853010570	POT family; Region: PTR2; pfam00854
1133853010571	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1133853010572	DNA photolyase; Region: DNA_photolyase; pfam00875
1133853010573	hypothetical protein; Provisional; Region: PRK10167
1133853010574	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1133853010575	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133853010576	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853010577	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133853010578	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133853010579	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853010580	RHS protein; Region: RHS; pfam03527
1133853010581	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853010582	PAAR motif; Region: PAAR_motif; cl15808
1133853010583	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853010584	RHS Repeat; Region: RHS_repeat; pfam05593
1133853010585	RHS Repeat; Region: RHS_repeat; pfam05593
1133853010586	RHS Repeat; Region: RHS_repeat; cl11982
1133853010587	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853010588	RHS Repeat; Region: RHS_repeat; pfam05593
1133853010589	RHS Repeat; Region: RHS_repeat; pfam05593
1133853010590	RHS protein; Region: RHS; pfam03527
1133853010591	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853010592	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1133853010593	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1133853010594	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1133853010595	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133853010596	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1133853010597	sensor protein KdpD; Provisional; Region: PRK10490
1133853010598	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1133853010599	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1133853010600	Ligand Binding Site [chemical binding]; other site
1133853010601	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1133853010602	GAF domain; Region: GAF_3; pfam13492
1133853010603	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853010604	dimer interface [polypeptide binding]; other site
1133853010605	phosphorylation site [posttranslational modification]
1133853010606	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853010607	ATP binding site [chemical binding]; other site
1133853010608	Mg2+ binding site [ion binding]; other site
1133853010609	G-X-G motif; other site
1133853010610	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1133853010611	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853010612	active site
1133853010613	phosphorylation site [posttranslational modification]
1133853010614	intermolecular recognition site; other site
1133853010615	dimerization interface [polypeptide binding]; other site
1133853010616	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853010617	DNA binding site [nucleotide binding]
1133853010618	ornithine decarboxylase; Provisional; Region: PRK13578
1133853010619	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133853010620	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133853010621	homodimer interface [polypeptide binding]; other site
1133853010622	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853010623	catalytic residue [active]
1133853010624	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133853010625	putrescine transporter; Provisional; Region: potE; PRK10655
1133853010626	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1133853010627	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1133853010628	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1133853010629	active site
1133853010630	substrate binding site [chemical binding]; other site
1133853010631	metal binding site [ion binding]; metal-binding site
1133853010632	replication initiation regulator SeqA; Provisional; Region: PRK11187
1133853010633	acyl-CoA esterase; Provisional; Region: PRK10673
1133853010634	PGAP1-like protein; Region: PGAP1; pfam07819
1133853010635	LexA regulated protein; Provisional; Region: PRK11675
1133853010636	flavodoxin FldA; Validated; Region: PRK09267
1133853010637	ryhB-regulated fur leader peptide; Provisional; Region: PRK14761
1133853010638	ferric uptake regulator; Provisional; Region: fur; PRK09462
1133853010639	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1133853010640	metal binding site 2 [ion binding]; metal-binding site
1133853010641	putative DNA binding helix; other site
1133853010642	metal binding site 1 [ion binding]; metal-binding site
1133853010643	dimer interface [polypeptide binding]; other site
1133853010644	structural Zn2+ binding site [ion binding]; other site
1133853010645	YbfN-like lipoprotein; Region: YbfN; pfam13982
1133853010646	outer membrane porin, OprD family; Region: OprD; pfam03573
1133853010647	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1133853010648	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1133853010649	active site
1133853010650	HIGH motif; other site
1133853010651	nucleotide binding site [chemical binding]; other site
1133853010652	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1133853010653	KMSKS motif; other site
1133853010654	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1133853010655	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1133853010656	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133853010657	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853010658	active site turn [active]
1133853010659	phosphorylation site [posttranslational modification]
1133853010660	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1133853010661	HPr interaction site; other site
1133853010662	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1133853010663	active site
1133853010664	phosphorylation site [posttranslational modification]
1133853010665	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1133853010666	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1133853010667	active site
1133853010668	trimer interface [polypeptide binding]; other site
1133853010669	allosteric site; other site
1133853010670	active site lid [active]
1133853010671	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1133853010672	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1133853010673	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1133853010674	active site
1133853010675	dimer interface [polypeptide binding]; other site
1133853010676	MarR family; Region: MarR; pfam01047
1133853010677	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133853010678	ROK family; Region: ROK; pfam00480
1133853010679	UMP phosphatase; Provisional; Region: PRK10444
1133853010680	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853010681	active site
1133853010682	motif I; other site
1133853010683	motif II; other site
1133853010684	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853010685	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1133853010686	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1133853010687	active site
1133853010688	dimer interface [polypeptide binding]; other site
1133853010689	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1133853010690	Ligand Binding Site [chemical binding]; other site
1133853010691	Molecular Tunnel; other site
1133853010692	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1133853010693	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1133853010694	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1133853010695	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1133853010696	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853010697	FeS/SAM binding site; other site
1133853010698	TRAM domain; Region: TRAM; pfam01938
1133853010699	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1133853010700	PhoH-like protein; Region: PhoH; pfam02562
1133853010701	metal-binding heat shock protein; Provisional; Region: PRK00016
1133853010702	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1133853010703	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133853010704	Transporter associated domain; Region: CorC_HlyC; smart01091
1133853010705	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1133853010706	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1133853010707	putative active site [active]
1133853010708	catalytic triad [active]
1133853010709	putative dimer interface [polypeptide binding]; other site
1133853010710	potential frameshift: common BLAST hit: gi|260853907|ref|YP_003227798.1| rhomboid family protein
1133853010711	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1133853010712	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853010713	substrate binding pocket [chemical binding]; other site
1133853010714	membrane-bound complex binding site; other site
1133853010715	hinge residues; other site
1133853010716	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853010717	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853010718	dimer interface [polypeptide binding]; other site
1133853010719	conserved gate region; other site
1133853010720	putative PBP binding loops; other site
1133853010721	ABC-ATPase subunit interface; other site
1133853010722	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133853010723	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853010724	dimer interface [polypeptide binding]; other site
1133853010725	conserved gate region; other site
1133853010726	putative PBP binding loops; other site
1133853010727	ABC-ATPase subunit interface; other site
1133853010728	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1133853010729	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133853010730	Walker A/P-loop; other site
1133853010731	ATP binding site [chemical binding]; other site
1133853010732	Q-loop/lid; other site
1133853010733	ABC transporter signature motif; other site
1133853010734	Walker B; other site
1133853010735	D-loop; other site
1133853010736	H-loop/switch region; other site
1133853010737	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1133853010738	active site
1133853010739	tetramer interface [polypeptide binding]; other site
1133853010740	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1133853010741	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1133853010742	nucleotide binding site [chemical binding]; other site
1133853010743	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1133853010744	SBD interface [polypeptide binding]; other site
1133853010745	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1133853010746	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1133853010747	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133853010748	Sel1-like repeats; Region: SEL1; smart00671
1133853010749	Sel1-like repeats; Region: SEL1; smart00671
1133853010750	Sel1-like repeats; Region: SEL1; smart00671
1133853010751	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
1133853010752	HSP70 interaction site [polypeptide binding]; other site
1133853010753	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1133853010754	Sel1-like repeats; Region: SEL1; smart00671
1133853010755	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133853010756	Sel1-like repeats; Region: SEL1; smart00671
1133853010757	Sel1-like repeats; Region: SEL1; smart00671
1133853010758	Sel1-like repeats; Region: SEL1; smart00671
1133853010759	Sel1-like repeats; Region: SEL1; smart00671
1133853010760	Sel1-like repeats; Region: SEL1; smart00671
1133853010761	Sel1-like repeats; Region: SEL1; smart00671
1133853010762	hypothetical protein; Provisional; Region: PRK11032
1133853010763	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1133853010764	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1133853010765	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1133853010766	HIGH motif; other site
1133853010767	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1133853010768	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1133853010769	active site
1133853010770	KMSKS motif; other site
1133853010771	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1133853010772	tRNA binding surface [nucleotide binding]; other site
1133853010773	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1133853010774	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1133853010775	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1133853010776	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1133853010777	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1133853010778	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1133853010779	active site
1133853010780	(T/H)XGH motif; other site
1133853010781	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133853010782	catalytic core [active]
1133853010783	ribosome-associated protein; Provisional; Region: PRK11538
1133853010784	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1133853010785	penicillin-binding protein 2; Provisional; Region: PRK10795
1133853010786	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1133853010787	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1133853010788	cell wall shape-determining protein; Provisional; Region: PRK10794
1133853010789	rare lipoprotein A; Provisional; Region: PRK10672
1133853010790	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1133853010791	Sporulation related domain; Region: SPOR; pfam05036
1133853010792	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1133853010793	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1133853010794	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1133853010795	hypothetical protein; Provisional; Region: PRK04998
1133853010796	lipoate-protein ligase B; Provisional; Region: PRK14342
1133853010797	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1133853010798	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853010799	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1133853010800	substrate binding pocket [chemical binding]; other site
1133853010801	dimerization interface [polypeptide binding]; other site
1133853010802	lipoyl synthase; Provisional; Region: PRK05481
1133853010803	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853010804	FeS/SAM binding site; other site
1133853010805	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1133853010806	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1133853010807	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1133853010808	putative active site [active]
1133853010809	catalytic triad [active]
1133853010810	putative dimer interface [polypeptide binding]; other site
1133853010811	chromosome condensation membrane protein; Provisional; Region: PRK14196
1133853010812	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133853010813	DNA-binding site [nucleotide binding]; DNA binding site
1133853010814	RNA-binding motif; other site
1133853010815	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1133853010816	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1133853010817	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1133853010818	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1133853010819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853010820	active site
1133853010821	phosphorylation site [posttranslational modification]
1133853010822	intermolecular recognition site; other site
1133853010823	dimerization interface [polypeptide binding]; other site
1133853010824	Transcriptional regulator; Region: CitT; pfam12431
1133853010825	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1133853010826	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853010827	putative active site [active]
1133853010828	heme pocket [chemical binding]; other site
1133853010829	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853010830	ATP binding site [chemical binding]; other site
1133853010831	Mg2+ binding site [ion binding]; other site
1133853010832	G-X-G motif; other site
1133853010833	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1133853010834	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1133853010835	putative active site [active]
1133853010836	(T/H)XGH motif; other site
1133853010837	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1133853010838	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1133853010839	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1133853010840	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1133853010841	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1133853010842	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133853010843	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1133853010844	transmembrane helices; other site
1133853010845	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1133853010846	B1 nucleotide binding pocket [chemical binding]; other site
1133853010847	B2 nucleotide binding pocket [chemical binding]; other site
1133853010848	CAS motifs; other site
1133853010849	active site
1133853010850	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1133853010851	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1133853010852	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1133853010853	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853010854	NAD binding site [chemical binding]; other site
1133853010855	catalytic Zn binding site [ion binding]; other site
1133853010856	structural Zn binding site [ion binding]; other site
1133853010857	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853010858	Ligand Binding Site [chemical binding]; other site
1133853010859	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1133853010860	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1133853010861	catalytic residue [active]
1133853010862	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1133853010863	catalytic residues [active]
1133853010864	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853010865	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853010866	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1133853010867	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1133853010868	dimer interface [polypeptide binding]; other site
1133853010869	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1133853010870	catalytic triad [active]
1133853010871	peroxidatic and resolving cysteines [active]
1133853010872	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1133853010873	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1133853010874	dimerization domain [polypeptide binding]; other site
1133853010875	dimer interface [polypeptide binding]; other site
1133853010876	catalytic residues [active]
1133853010877	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1133853010878	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853010879	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853010880	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1133853010881	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133853010882	Active Sites [active]
1133853010883	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1133853010884	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1133853010885	ParB-like nuclease domain; Region: ParBc; pfam02195
1133853010886	methionine aminotransferase; Validated; Region: PRK09082
1133853010887	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853010888	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853010889	homodimer interface [polypeptide binding]; other site
1133853010890	catalytic residue [active]
1133853010891	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1133853010892	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1133853010893	putative active site [active]
1133853010894	metal binding site [ion binding]; metal-binding site
1133853010895	Uncharacterized small protein [Function unknown]; Region: COG2879
1133853010896	carbon starvation protein A; Provisional; Region: PRK15015
1133853010897	Carbon starvation protein CstA; Region: CstA; pfam02554
1133853010898	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1133853010899	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133853010900	CoenzymeA binding site [chemical binding]; other site
1133853010901	subunit interaction site [polypeptide binding]; other site
1133853010902	PHB binding site; other site
1133853010903	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1133853010904	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1133853010905	putative NAD(P) binding site [chemical binding]; other site
1133853010906	active site
1133853010907	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1133853010908	hydrophobic substrate binding pocket; other site
1133853010909	Isochorismatase family; Region: Isochorismatase; pfam00857
1133853010910	active site
1133853010911	conserved cis-peptide bond; other site
1133853010912	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1133853010913	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1133853010914	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1133853010915	acyl-activating enzyme (AAE) consensus motif; other site
1133853010916	active site
1133853010917	AMP binding site [chemical binding]; other site
1133853010918	substrate binding site [chemical binding]; other site
1133853010919	isochorismate synthase EntC; Provisional; Region: PRK15016
1133853010920	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1133853010921	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1133853010922	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1133853010923	siderophore binding site; other site
1133853010924	enterobactin exporter EntS; Provisional; Region: PRK10489
1133853010925	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853010926	putative substrate translocation pore; other site
1133853010927	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1133853010928	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853010929	ABC-ATPase subunit  interface; other site
1133853010930	dimer interface [polypeptide binding]; other site
1133853010931	putative PBP binding regions; other site
1133853010932	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1133853010933	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853010934	ABC-ATPase subunit  interface; other site
1133853010935	dimer interface [polypeptide binding]; other site
1133853010936	putative PBP binding regions; other site
1133853010937	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1133853010938	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133853010939	Walker A/P-loop; other site
1133853010940	ATP binding site [chemical binding]; other site
1133853010941	Q-loop/lid; other site
1133853010942	ABC transporter signature motif; other site
1133853010943	Walker B; other site
1133853010944	D-loop; other site
1133853010945	H-loop/switch region; other site
1133853010946	LPS O-antigen length regulator; Provisional; Region: PRK10381
1133853010947	Chain length determinant protein; Region: Wzz; pfam02706
1133853010948	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133853010949	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1133853010950	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1133853010951	acyl-activating enzyme (AAE) consensus motif; other site
1133853010952	AMP binding site [chemical binding]; other site
1133853010953	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133853010954	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1133853010955	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1133853010956	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1133853010957	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1133853010958	outer membrane receptor FepA; Provisional; Region: PRK13524
1133853010959	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853010960	N-terminal plug; other site
1133853010961	ligand-binding site [chemical binding]; other site
1133853010962	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1133853010963	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1133853010964	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1133853010965	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853010966	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133853010967	Hok/gef family; Region: HOK_GEF; pfam01848
1133853010968	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853010969	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133853010970	Hok/gef family; Region: HOK_GEF; pfam01848
1133853010971	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1133853010972	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1133853010973	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1133853010974	hypothetical protein; Provisional; Region: PRK10250
1133853010975	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1133853010976	dimer interface [polypeptide binding]; other site
1133853010977	FMN binding site [chemical binding]; other site
1133853010978	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1133853010979	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133853010980	phenylalanine transporter; Provisional; Region: PRK10249
1133853010981	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1133853010982	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1133853010983	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853010984	periplasmic copper-binding protein; Provisional; Region: PRK09838
1133853010985	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1133853010986	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
1133853010987	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853010988	active site
1133853010989	phosphorylation site [posttranslational modification]
1133853010990	intermolecular recognition site; other site
1133853010991	dimerization interface [polypeptide binding]; other site
1133853010992	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853010993	DNA binding site [nucleotide binding]
1133853010994	sensor kinase CusS; Provisional; Region: PRK09835
1133853010995	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853010996	dimerization interface [polypeptide binding]; other site
1133853010997	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853010998	dimer interface [polypeptide binding]; other site
1133853010999	phosphorylation site [posttranslational modification]
1133853011000	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853011001	ATP binding site [chemical binding]; other site
1133853011002	Mg2+ binding site [ion binding]; other site
1133853011003	G-X-G motif; other site
1133853011004	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133853011005	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133853011006	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133853011007	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1133853011008	Uncharacterized conserved protein [Function unknown]; Region: COG5435
1133853011009	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853011010	RHS Repeat; Region: RHS_repeat; cl11982
1133853011011	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853011012	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133853011013	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853011014	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133853011015	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133853011016	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
1133853011017	active site
1133853011018	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
1133853011019	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1133853011020	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
1133853011021	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853011022	TPR motif; other site
1133853011023	binding surface
1133853011024	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
1133853011025	hypothetical protein; Provisional; Region: PRK09936
1133853011026	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133853011027	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853011028	potential protein location (hypothetical protein O3O_06475 [Escherichia coli O104:H4 str. 2009EL-2071]) that overlaps RNA (tRNA-R)
1133853011029	transcriptional regulator FimZ; Provisional; Region: PRK09935
1133853011030	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853011031	active site
1133853011032	phosphorylation site [posttranslational modification]
1133853011033	intermolecular recognition site; other site
1133853011034	dimerization interface [polypeptide binding]; other site
1133853011035	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853011036	DNA binding residues [nucleotide binding]
1133853011037	dimerization interface [polypeptide binding]; other site
1133853011038	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1133853011039	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1133853011040	outer membrane usher protein FimD; Provisional; Region: PRK15198
1133853011041	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853011042	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853011043	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853011044	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1133853011045	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853011046	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853011047	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1133853011048	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1133853011049	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1133853011050	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1133853011051	homodimer interface [polypeptide binding]; other site
1133853011052	NADP binding site [chemical binding]; other site
1133853011053	substrate binding site [chemical binding]; other site
1133853011054	ribosome-associated protein; Provisional; Region: PRK11507
1133853011055	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1133853011056	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1133853011057	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1133853011058	active site
1133853011059	HIGH motif; other site
1133853011060	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1133853011061	KMSKS motif; other site
1133853011062	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1133853011063	tRNA binding surface [nucleotide binding]; other site
1133853011064	anticodon binding site; other site
1133853011065	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1133853011066	substrate binding site [chemical binding]; other site
1133853011067	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1133853011068	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1133853011069	putative active site [active]
1133853011070	putative metal binding site [ion binding]; other site
1133853011071	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1133853011072	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1133853011073	ATP-grasp domain; Region: ATP-grasp; pfam02222
1133853011074	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1133853011075	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1133853011076	putative substrate binding site [chemical binding]; other site
1133853011077	nucleotide binding site [chemical binding]; other site
1133853011078	nucleotide binding site [chemical binding]; other site
1133853011079	homodimer interface [polypeptide binding]; other site
1133853011080	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1133853011081	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1133853011082	membrane protein FdrA; Validated; Region: PRK06091
1133853011083	CoA binding domain; Region: CoA_binding; pfam02629
1133853011084	CoA-ligase; Region: Ligase_CoA; pfam00549
1133853011085	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
1133853011086	allantoate amidohydrolase; Region: AllC; TIGR03176
1133853011087	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1133853011088	active site
1133853011089	metal binding site [ion binding]; metal-binding site
1133853011090	dimer interface [polypeptide binding]; other site
1133853011091	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1133853011092	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
1133853011093	Cupin domain; Region: Cupin_2; cl17218
1133853011094	glycerate kinase II; Provisional; Region: PRK09932
1133853011095	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1133853011096	allantoinase; Provisional; Region: PRK08044
1133853011097	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1133853011098	active site
1133853011099	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
1133853011100	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1133853011101	Na binding site [ion binding]; other site
1133853011102	substrate binding site [chemical binding]; other site
1133853011103	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1133853011104	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1133853011105	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1133853011106	glyoxylate carboligase; Provisional; Region: PRK11269
1133853011107	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133853011108	PYR/PP interface [polypeptide binding]; other site
1133853011109	dimer interface [polypeptide binding]; other site
1133853011110	TPP binding site [chemical binding]; other site
1133853011111	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133853011112	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1133853011113	TPP-binding site [chemical binding]; other site
1133853011114	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1133853011115	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133853011116	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133853011117	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1133853011118	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1133853011119	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1133853011120	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853011121	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853011122	dimerization interface [polypeptide binding]; other site
1133853011123	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1133853011124	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1133853011125	active site residue [active]
1133853011126	Winged helix-turn helix; Region: HTH_29; pfam13551
1133853011127	Helix-turn-helix domain; Region: HTH_28; pfam13518
1133853011128	hypothetical protein; Provisional; Region: PRK14710
1133853011129	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853011130	RHS protein; Region: RHS; pfam03527
1133853011131	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853011132	PAAR motif; Region: PAAR_motif; cl15808
1133853011133	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853011134	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011135	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011136	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011137	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011138	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853011139	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011140	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011141	RHS protein; Region: RHS; pfam03527
1133853011142	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853011143	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1133853011144	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1133853011145	FtsX-like permease family; Region: FtsX; pfam02687
1133853011146	FtsX-like permease family; Region: FtsX; pfam02687
1133853011147	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1133853011148	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133853011149	Walker A/P-loop; other site
1133853011150	ATP binding site [chemical binding]; other site
1133853011151	Q-loop/lid; other site
1133853011152	ABC transporter signature motif; other site
1133853011153	Walker B; other site
1133853011154	D-loop; other site
1133853011155	H-loop/switch region; other site
1133853011156	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1133853011157	active site
1133853011158	catalytic triad [active]
1133853011159	oxyanion hole [active]
1133853011160	switch loop; other site
1133853011161	oxidoreductase; Provisional; Region: PRK08017
1133853011162	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1133853011163	NADP binding site [chemical binding]; other site
1133853011164	active site
1133853011165	steroid binding site; other site
1133853011166	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1133853011167	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1133853011168	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
1133853011169	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1133853011170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853011171	Walker A/P-loop; other site
1133853011172	ATP binding site [chemical binding]; other site
1133853011173	Q-loop/lid; other site
1133853011174	ABC transporter signature motif; other site
1133853011175	Walker B; other site
1133853011176	D-loop; other site
1133853011177	H-loop/switch region; other site
1133853011178	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1133853011179	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1133853011180	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1133853011181	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1133853011182	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1133853011183	DNA binding residues [nucleotide binding]
1133853011184	dimer interface [polypeptide binding]; other site
1133853011185	copper binding site [ion binding]; other site
1133853011186	amino acid transporter; Region: 2A0306; TIGR00909
1133853011187	glutaminase; Reviewed; Region: PRK12356
1133853011188	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1133853011189	copper exporting ATPase; Provisional; Region: copA; PRK10671
1133853011190	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133853011191	metal-binding site [ion binding]
1133853011192	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133853011193	metal-binding site [ion binding]
1133853011194	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133853011195	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853011196	motif II; other site
1133853011197	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1133853011198	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853011199	sequence-specific DNA binding site [nucleotide binding]; other site
1133853011200	salt bridge; other site
1133853011201	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1133853011202	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1133853011203	putative deacylase active site [active]
1133853011204	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1133853011205	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1133853011206	active site
1133853011207	metal binding site [ion binding]; metal-binding site
1133853011208	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1133853011209	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011210	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853011211	putative substrate translocation pore; other site
1133853011212	putative cation:proton antiport protein; Provisional; Region: PRK10669
1133853011213	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1133853011214	TrkA-N domain; Region: TrkA_N; pfam02254
1133853011215	inosine/guanosine kinase; Provisional; Region: PRK15074
1133853011216	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853011217	acetyl esterase; Provisional; Region: PRK10162
1133853011218	ferrochelatase; Region: hemH; TIGR00109
1133853011219	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1133853011220	C-terminal domain interface [polypeptide binding]; other site
1133853011221	active site
1133853011222	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1133853011223	active site
1133853011224	N-terminal domain interface [polypeptide binding]; other site
1133853011225	adenylate kinase; Reviewed; Region: adk; PRK00279
1133853011226	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1133853011227	AMP-binding site [chemical binding]; other site
1133853011228	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1133853011229	heat shock protein 90; Provisional; Region: PRK05218
1133853011230	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853011231	ATP binding site [chemical binding]; other site
1133853011232	Mg2+ binding site [ion binding]; other site
1133853011233	G-X-G motif; other site
1133853011234	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
1133853011235	RecR protein; Region: RecR; pfam02132
1133853011236	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1133853011237	putative active site [active]
1133853011238	putative metal-binding site [ion binding]; other site
1133853011239	tetramer interface [polypeptide binding]; other site
1133853011240	hypothetical protein; Validated; Region: PRK00153
1133853011241	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1133853011242	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853011243	Walker A motif; other site
1133853011244	ATP binding site [chemical binding]; other site
1133853011245	Walker B motif; other site
1133853011246	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1133853011247	arginine finger; other site
1133853011248	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1133853011249	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1133853011250	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1133853011251	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853011252	active site
1133853011253	hypothetical protein; Provisional; Region: PRK10527
1133853011254	primosomal replication protein N''; Provisional; Region: PRK10093
1133853011255	hypothetical protein; Provisional; Region: PRK11038
1133853011256	hypothetical protein; Provisional; Region: PRK11281
1133853011257	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1133853011258	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1133853011259	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133853011260	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1133853011261	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853011262	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1133853011263	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1133853011264	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853011265	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1133853011266	Protein export membrane protein; Region: SecD_SecF; cl14618
1133853011267	Protein export membrane protein; Region: SecD_SecF; cl14618
1133853011268	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
1133853011269	gene expression modulator; Provisional; Region: PRK10945
1133853011270	maltose O-acetyltransferase; Provisional; Region: PRK10092
1133853011271	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1133853011272	active site
1133853011273	substrate binding site [chemical binding]; other site
1133853011274	trimer interface [polypeptide binding]; other site
1133853011275	CoA binding site [chemical binding]; other site
1133853011276	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1133853011277	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1133853011278	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133853011279	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853011280	Uncharacterized conserved protein [Function unknown]; Region: COG5507
1133853011281	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1133853011282	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1133853011283	DNA binding site [nucleotide binding]
1133853011284	active site
1133853011285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1133853011286	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1133853011287	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1133853011288	active site
1133853011289	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1133853011290	catalytic triad [active]
1133853011291	dimer interface [polypeptide binding]; other site
1133853011292	ammonium transporter; Provisional; Region: PRK10666
1133853011293	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1133853011294	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1133853011295	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1133853011296	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853011297	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1133853011298	Walker A/P-loop; other site
1133853011299	ATP binding site [chemical binding]; other site
1133853011300	Q-loop/lid; other site
1133853011301	ABC transporter signature motif; other site
1133853011302	Walker B; other site
1133853011303	D-loop; other site
1133853011304	H-loop/switch region; other site
1133853011305	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133853011306	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1133853011307	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853011308	Walker A/P-loop; other site
1133853011309	ATP binding site [chemical binding]; other site
1133853011310	Q-loop/lid; other site
1133853011311	ABC transporter signature motif; other site
1133853011312	Walker B; other site
1133853011313	D-loop; other site
1133853011314	H-loop/switch region; other site
1133853011315	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1133853011316	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853011317	putative DNA binding site [nucleotide binding]; other site
1133853011318	putative Zn2+ binding site [ion binding]; other site
1133853011319	AsnC family; Region: AsnC_trans_reg; pfam01037
1133853011320	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1133853011321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853011322	active site
1133853011323	motif I; other site
1133853011324	motif II; other site
1133853011325	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1133853011326	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1133853011327	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1133853011328	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1133853011329	Ligand Binding Site [chemical binding]; other site
1133853011330	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1133853011331	active site
1133853011332	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1133853011333	periplasmic folding chaperone; Provisional; Region: PRK10788
1133853011334	SurA N-terminal domain; Region: SurA_N_3; cl07813
1133853011335	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1133853011336	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1133853011337	IHF dimer interface [polypeptide binding]; other site
1133853011338	IHF - DNA interface [nucleotide binding]; other site
1133853011339	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1133853011340	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1133853011341	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1133853011342	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853011343	Walker A motif; other site
1133853011344	ATP binding site [chemical binding]; other site
1133853011345	Walker B motif; other site
1133853011346	arginine finger; other site
1133853011347	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1133853011348	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1133853011349	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1133853011350	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853011351	Walker A motif; other site
1133853011352	ATP binding site [chemical binding]; other site
1133853011353	Walker B motif; other site
1133853011354	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133853011355	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1133853011356	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1133853011357	oligomer interface [polypeptide binding]; other site
1133853011358	active site residues [active]
1133853011359	trigger factor; Provisional; Region: tig; PRK01490
1133853011360	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133853011361	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1133853011362	transcriptional regulator BolA; Provisional; Region: PRK11628
1133853011363	hypothetical protein; Provisional; Region: PRK11627
1133853011364	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1133853011365	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1133853011366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011367	putative substrate translocation pore; other site
1133853011368	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1133853011369	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1133853011370	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1133853011371	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1133853011372	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1133853011373	D-pathway; other site
1133853011374	Putative ubiquinol binding site [chemical binding]; other site
1133853011375	Low-spin heme (heme b) binding site [chemical binding]; other site
1133853011376	Putative water exit pathway; other site
1133853011377	Binuclear center (heme o3/CuB) [ion binding]; other site
1133853011378	K-pathway; other site
1133853011379	Putative proton exit pathway; other site
1133853011380	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1133853011381	Subunit I/III interface [polypeptide binding]; other site
1133853011382	Subunit III/IV interface [polypeptide binding]; other site
1133853011383	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1133853011384	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1133853011385	UbiA prenyltransferase family; Region: UbiA; pfam01040
1133853011386	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
1133853011387	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1133853011388	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133853011389	Sel1 repeat; Region: Sel1; pfam08238
1133853011390	Sel1-like repeats; Region: SEL1; smart00671
1133853011391	Sel1-like repeats; Region: SEL1; smart00671
1133853011392	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011393	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853011394	putative substrate translocation pore; other site
1133853011395	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1133853011396	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1133853011397	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1133853011398	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1133853011399	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1133853011400	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1133853011401	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1133853011402	conserved cys residue [active]
1133853011403	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1133853011404	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1133853011405	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1133853011406	Ligand Binding Site [chemical binding]; other site
1133853011407	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1133853011408	active site residue [active]
1133853011409	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1133853011410	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1133853011411	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1133853011412	substrate binding pocket [chemical binding]; other site
1133853011413	chain length determination region; other site
1133853011414	substrate-Mg2+ binding site; other site
1133853011415	catalytic residues [active]
1133853011416	aspartate-rich region 1; other site
1133853011417	active site lid residues [active]
1133853011418	aspartate-rich region 2; other site
1133853011419	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1133853011420	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1133853011421	TPP-binding site; other site
1133853011422	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1133853011423	PYR/PP interface [polypeptide binding]; other site
1133853011424	dimer interface [polypeptide binding]; other site
1133853011425	TPP binding site [chemical binding]; other site
1133853011426	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1133853011427	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853011428	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853011429	active site
1133853011430	catalytic tetrad [active]
1133853011431	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1133853011432	tetramer interfaces [polypeptide binding]; other site
1133853011433	binuclear metal-binding site [ion binding]; other site
1133853011434	thiamine monophosphate kinase; Provisional; Region: PRK05731
1133853011435	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1133853011436	ATP binding site [chemical binding]; other site
1133853011437	dimerization interface [polypeptide binding]; other site
1133853011438	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1133853011439	putative RNA binding site [nucleotide binding]; other site
1133853011440	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1133853011441	homopentamer interface [polypeptide binding]; other site
1133853011442	active site
1133853011443	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1133853011444	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1133853011445	catalytic motif [active]
1133853011446	Zn binding site [ion binding]; other site
1133853011447	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1133853011448	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1133853011449	ATP cone domain; Region: ATP-cone; pfam03477
1133853011450	potential frameshift: common BLAST hit: gi|260866570|ref|YP_003232972.1| putative lipoprotein
1133853011451	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1133853011452	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853011453	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1133853011454	active site
1133853011455	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1133853011456	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1133853011457	Protein export membrane protein; Region: SecD_SecF; pfam02355
1133853011458	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1133853011459	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1133853011460	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1133853011461	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1133853011462	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1133853011463	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1133853011464	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1133853011465	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1133853011466	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1133853011467	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1133853011468	maltodextrin glucosidase; Provisional; Region: PRK10785
1133853011469	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1133853011470	homodimer interface [polypeptide binding]; other site
1133853011471	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1133853011472	active site
1133853011473	homodimer interface [polypeptide binding]; other site
1133853011474	catalytic site [active]
1133853011475	putative proline-specific permease; Provisional; Region: proY; PRK10580
1133853011476	Spore germination protein; Region: Spore_permease; cl17796
1133853011477	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1133853011478	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1133853011479	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1133853011480	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853011481	putative active site [active]
1133853011482	heme pocket [chemical binding]; other site
1133853011483	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853011484	dimer interface [polypeptide binding]; other site
1133853011485	phosphorylation site [posttranslational modification]
1133853011486	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853011487	ATP binding site [chemical binding]; other site
1133853011488	Mg2+ binding site [ion binding]; other site
1133853011489	G-X-G motif; other site
1133853011490	transcriptional regulator PhoB; Provisional; Region: PRK10161
1133853011491	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853011492	active site
1133853011493	phosphorylation site [posttranslational modification]
1133853011494	intermolecular recognition site; other site
1133853011495	dimerization interface [polypeptide binding]; other site
1133853011496	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853011497	DNA binding site [nucleotide binding]
1133853011498	exonuclease subunit SbcD; Provisional; Region: PRK10966
1133853011499	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1133853011500	active site
1133853011501	metal binding site [ion binding]; metal-binding site
1133853011502	DNA binding site [nucleotide binding]
1133853011503	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1133853011504	exonuclease subunit SbcC; Provisional; Region: PRK10246
1133853011505	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853011506	Walker A/P-loop; other site
1133853011507	ATP binding site [chemical binding]; other site
1133853011508	Q-loop/lid; other site
1133853011509	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853011510	ABC transporter signature motif; other site
1133853011511	Walker B; other site
1133853011512	D-loop; other site
1133853011513	H-loop/switch region; other site
1133853011514	MFS transport protein AraJ; Provisional; Region: PRK10091
1133853011515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011516	putative substrate translocation pore; other site
1133853011517	fructokinase; Reviewed; Region: PRK09557
1133853011518	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853011519	nucleotide binding site [chemical binding]; other site
1133853011520	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1133853011521	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
1133853011522	hypothetical protein; Provisional; Region: PRK10579
1133853011523	hypothetical protein; Provisional; Region: PRK10481
1133853011524	hypothetical protein; Provisional; Region: PRK10380
1133853011525	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1133853011526	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1133853011527	ADP binding site [chemical binding]; other site
1133853011528	magnesium binding site [ion binding]; other site
1133853011529	putative shikimate binding site; other site
1133853011530	hypothetical protein; Validated; Region: PRK00124
1133853011531	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1133853011532	pyrroline-5-carboxylate reductase; Region: PLN02688
1133853011533	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1133853011534	MASE2 domain; Region: MASE2; pfam05230
1133853011535	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133853011536	metal binding site [ion binding]; metal-binding site
1133853011537	active site
1133853011538	I-site; other site
1133853011539	hypothetical protein; Provisional; Region: PRK11505
1133853011540	psiF repeat; Region: PsiF_repeat; pfam07769
1133853011541	psiF repeat; Region: PsiF_repeat; pfam07769
1133853011542	alkaline phosphatase; Provisional; Region: PRK10518
1133853011543	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1133853011544	dimer interface [polypeptide binding]; other site
1133853011545	active site
1133853011546	anti-RssB factor; Provisional; Region: PRK10244
1133853011547	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1133853011548	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1133853011549	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1133853011550	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1133853011551	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1133853011552	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1133853011553	microcin B17 transporter; Reviewed; Region: PRK11098
1133853011554	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1133853011555	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1133853011556	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1133853011557	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1133853011558	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853011559	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853011560	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1133853011561	dimer interface [polypeptide binding]; other site
1133853011562	active site
1133853011563	Schiff base residues; other site
1133853011564	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1133853011565	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
1133853011566	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133853011567	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853011568	dimer interface [polypeptide binding]; other site
1133853011569	conserved gate region; other site
1133853011570	putative PBP binding loops; other site
1133853011571	ABC-ATPase subunit interface; other site
1133853011572	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
1133853011573	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1133853011574	Walker A/P-loop; other site
1133853011575	ATP binding site [chemical binding]; other site
1133853011576	Q-loop/lid; other site
1133853011577	ABC transporter signature motif; other site
1133853011578	Walker B; other site
1133853011579	D-loop; other site
1133853011580	H-loop/switch region; other site
1133853011581	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1133853011582	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853011583	substrate binding pocket [chemical binding]; other site
1133853011584	membrane-bound complex binding site; other site
1133853011585	hinge residues; other site
1133853011586	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1133853011587	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1133853011588	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1133853011589	DXD motif; other site
1133853011590	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1133853011591	putative trimer interface [polypeptide binding]; other site
1133853011592	putative CoA binding site [chemical binding]; other site
1133853011593	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1133853011594	putative metal binding site [ion binding]; other site
1133853011595	putative homodimer interface [polypeptide binding]; other site
1133853011596	putative homotetramer interface [polypeptide binding]; other site
1133853011597	putative homodimer-homodimer interface [polypeptide binding]; other site
1133853011598	putative allosteric switch controlling residues; other site
1133853011599	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1133853011600	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1133853011601	substrate binding site [chemical binding]; other site
1133853011602	catalytic Zn binding site [ion binding]; other site
1133853011603	NAD binding site [chemical binding]; other site
1133853011604	structural Zn binding site [ion binding]; other site
1133853011605	dimer interface [polypeptide binding]; other site
1133853011606	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1133853011607	S-formylglutathione hydrolase; Region: PLN02442
1133853011608	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1133853011609	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
1133853011610	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011611	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011612	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
1133853011613	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
1133853011614	active site
1133853011615	catalytic residues [active]
1133853011616	metal binding site [ion binding]; metal-binding site
1133853011617	DmpG-like communication domain; Region: DmpG_comm; pfam07836
1133853011618	acetaldehyde dehydrogenase; Validated; Region: PRK08300
1133853011619	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1133853011620	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
1133853011621	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
1133853011622	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
1133853011623	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1133853011624	nucleophilic elbow; other site
1133853011625	catalytic triad; other site
1133853011626	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
1133853011627	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1133853011628	putative active site [active]
1133853011629	Fe(II) binding site [ion binding]; other site
1133853011630	putative dimer interface [polypeptide binding]; other site
1133853011631	putative tetramer interface [polypeptide binding]; other site
1133853011632	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
1133853011633	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1133853011634	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
1133853011635	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133853011636	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133853011637	lac repressor; Reviewed; Region: lacI; PRK09526
1133853011638	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853011639	DNA binding site [nucleotide binding]
1133853011640	domain linker motif; other site
1133853011641	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1133853011642	ligand binding site [chemical binding]; other site
1133853011643	dimerization interface (open form) [polypeptide binding]; other site
1133853011644	dimerization interface (closed form) [polypeptide binding]; other site
1133853011645	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1133853011646	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1133853011647	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1133853011648	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1133853011649	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1133853011650	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1133853011651	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011652	putative substrate translocation pore; other site
1133853011653	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
1133853011654	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1133853011655	active site
1133853011656	substrate binding site [chemical binding]; other site
1133853011657	trimer interface [polypeptide binding]; other site
1133853011658	CoA binding site [chemical binding]; other site
1133853011659	putative cyanate transporter; Provisional; Region: cynX; PRK09705
1133853011660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853011661	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
1133853011662	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
1133853011663	oligomer interface [polypeptide binding]; other site
1133853011664	active site
1133853011665	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1133853011666	active site clefts [active]
1133853011667	zinc binding site [ion binding]; other site
1133853011668	dimer interface [polypeptide binding]; other site
1133853011669	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1133853011670	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853011671	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
1133853011672	dimerization interface [polypeptide binding]; other site
1133853011673	cytosine deaminase; Provisional; Region: PRK09230
1133853011674	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1133853011675	active site
1133853011676	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1133853011677	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1133853011678	Na binding site [ion binding]; other site
1133853011679	putative substrate binding site [chemical binding]; other site
1133853011680	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1133853011681	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
1133853011682	acyl-activating enzyme (AAE) consensus motif; other site
1133853011683	putative AMP binding site [chemical binding]; other site
1133853011684	putative active site [active]
1133853011685	putative CoA binding site [chemical binding]; other site
1133853011686	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1133853011687	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1133853011688	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1133853011689	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1133853011690	dimer interface [polypeptide binding]; other site
1133853011691	active site
1133853011692	citrylCoA binding site [chemical binding]; other site
1133853011693	oxalacetate/citrate binding site [chemical binding]; other site
1133853011694	coenzyme A binding site [chemical binding]; other site
1133853011695	catalytic triad [active]
1133853011696	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1133853011697	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1133853011698	tetramer interface [polypeptide binding]; other site
1133853011699	active site
1133853011700	Mg2+/Mn2+ binding site [ion binding]; other site
1133853011701	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1133853011702	Propionate catabolism activator; Region: PrpR_N; pfam06506
1133853011703	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853011704	Walker A motif; other site
1133853011705	ATP binding site [chemical binding]; other site
1133853011706	Walker B motif; other site
1133853011707	arginine finger; other site
1133853011708	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133853011709	hypothetical protein; Provisional; Region: PRK09929
1133853011710	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1133853011711	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1133853011712	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1133853011713	putative NAD(P) binding site [chemical binding]; other site
1133853011714	putative substrate binding site [chemical binding]; other site
1133853011715	catalytic Zn binding site [ion binding]; other site
1133853011716	structural Zn binding site [ion binding]; other site
1133853011717	dimer interface [polypeptide binding]; other site
1133853011718	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853011719	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853011720	TM-ABC transporter signature motif; other site
1133853011721	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853011722	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853011723	TM-ABC transporter signature motif; other site
1133853011724	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1133853011725	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853011726	Walker A/P-loop; other site
1133853011727	ATP binding site [chemical binding]; other site
1133853011728	Q-loop/lid; other site
1133853011729	ABC transporter signature motif; other site
1133853011730	Walker B; other site
1133853011731	D-loop; other site
1133853011732	H-loop/switch region; other site
1133853011733	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853011734	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1133853011735	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1133853011736	ligand binding site [chemical binding]; other site
1133853011737	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1133853011738	putative deaminase; Validated; Region: PRK06846
1133853011739	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1133853011740	active site
1133853011741	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1133853011742	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1133853011743	putative substrate binding site [chemical binding]; other site
1133853011744	nucleotide binding site [chemical binding]; other site
1133853011745	nucleotide binding site [chemical binding]; other site
1133853011746	homodimer interface [polypeptide binding]; other site
1133853011747	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1133853011748	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
1133853011749	CoA binding domain; Region: CoA_binding; pfam02629
1133853011750	CoA-ligase; Region: Ligase_CoA; pfam00549
1133853011751	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1133853011752	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1133853011753	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1133853011754	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1133853011755	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1133853011756	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1133853011757	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853011758	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853011759	dimerization interface [polypeptide binding]; other site
1133853011760	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853011761	DNA binding residues [nucleotide binding]
1133853011762	dimerization interface [polypeptide binding]; other site
1133853011763	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853011764	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133853011765	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133853011766	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853011767	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853011768	choline transport protein BetT; Provisional; Region: PRK09928
1133853011769	transcriptional regulator BetI; Validated; Region: PRK00767
1133853011770	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853011771	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1133853011772	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1133853011773	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1133853011774	tetrameric interface [polypeptide binding]; other site
1133853011775	NAD binding site [chemical binding]; other site
1133853011776	catalytic residues [active]
1133853011777	choline dehydrogenase; Validated; Region: PRK02106
1133853011778	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1133853011779	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133853011780	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1133853011781	iron-sulfur cluster-binding protein; Region: TIGR00273
1133853011782	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1133853011783	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1133853011784	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1133853011785	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1133853011786	Cysteine-rich domain; Region: CCG; pfam02754
1133853011787	Cysteine-rich domain; Region: CCG; pfam02754
1133853011788	Cupin; Region: Cupin_6; pfam12852
1133853011789	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133853011790	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853011791	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1133853011792	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1133853011793	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853011794	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1133853011795	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853011796	Predicted membrane protein [Function unknown]; Region: COG3059
1133853011797	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853011798	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853011799	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853011800	Predicted membrane protein [Function unknown]; Region: COG3059
1133853011801	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1133853011802	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853011803	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1133853011804	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1133853011805	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133853011806	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133853011807	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133853011808	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133853011809	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1133853011810	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1133853011811	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133853011812	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853011813	DNA binding residues [nucleotide binding]
1133853011814	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1133853011815	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853011816	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1133853011817	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1133853011818	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
1133853011819	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
1133853011820	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133853011821	catalytic loop [active]
1133853011822	iron binding site [ion binding]; other site
1133853011823	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1133853011824	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1133853011825	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1133853011826	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1133853011827	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1133853011828	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1133853011829	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1133853011830	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1133853011831	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1133853011832	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133853011833	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853011834	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133853011835	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1133853011836	active site
1133853011837	DNA binding site [nucleotide binding]
1133853011838	Int/Topo IB signature motif; other site
1133853011839	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853011840	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853011841	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853011842	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133853011843	DNA polymerase III psi subunit; Region: DNA_III_psi; cl11436
1133853011844	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1133853011845	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133853011846	catalytic residues [active]
1133853011847	catalytic nucleophile [active]
1133853011848	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133853011849	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133853011850	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133853011851	Synaptic Site I dimer interface [polypeptide binding]; other site
1133853011852	Homeodomain-like domain; Region: HTH_23; pfam13384
1133853011853	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1133853011854	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1133853011855	putative catalytic cysteine [active]
1133853011856	gamma-glutamyl kinase; Provisional; Region: PRK05429
1133853011857	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1133853011858	nucleotide binding site [chemical binding]; other site
1133853011859	homotetrameric interface [polypeptide binding]; other site
1133853011860	putative phosphate binding site [ion binding]; other site
1133853011861	putative allosteric binding site; other site
1133853011862	PUA domain; Region: PUA; pfam01472
1133853011863	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1133853011864	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133853011865	trimer interface [polypeptide binding]; other site
1133853011866	eyelet of channel; other site
1133853011867	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1133853011868	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1133853011869	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853011870	active site
1133853011871	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1133853011872	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1133853011873	metal binding site [ion binding]; metal-binding site
1133853011874	dimer interface [polypeptide binding]; other site
1133853011875	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1133853011876	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1133853011877	hypothetical protein; Reviewed; Region: PRK09588
1133853011878	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1133853011879	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133853011880	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853011881	Coenzyme A binding pocket [chemical binding]; other site
1133853011882	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1133853011883	active site
1133853011884	DNA polymerase IV; Validated; Region: PRK02406
1133853011885	DNA binding site [nucleotide binding]
1133853011886	hypothetical protein; Validated; Region: PRK06778
1133853011887	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133853011888	ligand binding site [chemical binding]; other site
1133853011889	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
1133853011890	FHIPEP family; Region: FHIPEP; pfam00771
1133853011891	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1133853011892	HicB family; Region: HicB; pfam05534
1133853011893	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133853011894	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133853011895	RelB antitoxin; Region: RelB; cl01171
1133853011896	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1133853011897	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1133853011898	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133853011899	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1133853011900	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1133853011901	putative active site [active]
1133853011902	putative dimer interface [polypeptide binding]; other site
1133853011903	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1133853011904	dimer interface [polypeptide binding]; other site
1133853011905	active site
1133853011906	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1133853011907	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1133853011908	active site
1133853011909	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1133853011910	C-lysozyme inhibitor; Provisional; Region: PRK09993
1133853011911	C-N hydrolase family amidase; Provisional; Region: PRK10438
1133853011912	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1133853011913	putative active site [active]
1133853011914	catalytic triad [active]
1133853011915	dimer interface [polypeptide binding]; other site
1133853011916	multimer interface [polypeptide binding]; other site
1133853011917	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133853011918	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133853011919	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133853011920	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133853011921	potential frameshift: common BLAST hit: gi|291281062|ref|YP_003497880.1| transposase yncI
1133853011922	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853011923	RHS protein; Region: RHS; pfam03527
1133853011924	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853011925	PAAR motif; Region: PAAR_motif; cl15808
1133853011926	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011927	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011928	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853011929	RHS Repeat; Region: RHS_repeat; pfam05593
1133853011930	RHS Repeat; Region: RHS_repeat; cl11982
1133853011931	RHS Repeat; Region: RHS_repeat; cl11982
1133853011932	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133853011933	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133853011934	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133853011935	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1133853011936	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1133853011937	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1133853011938	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1133853011939	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1133853011940	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1133853011941	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1133853011942	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1133853011943	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1133853011944	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1133853011945	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
1133853011946	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1133853011947	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1133853011948	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1133853011949	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1133853011950	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1133853011951	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853011952	Walker A motif; other site
1133853011953	ATP binding site [chemical binding]; other site
1133853011954	Walker B motif; other site
1133853011955	arginine finger; other site
1133853011956	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853011957	Walker A motif; other site
1133853011958	ATP binding site [chemical binding]; other site
1133853011959	Walker B motif; other site
1133853011960	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133853011961	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
1133853011962	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1133853011963	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1133853011964	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1133853011965	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1133853011966	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1133853011967	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1133853011968	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1133853011969	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1133853011970	ImpA domain protein; Region: DUF3702; pfam12486
1133853011971	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1133853011972	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1133853011973	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1133853011974	active site
1133853011975	catalytic site [active]
1133853011976	substrate binding site [chemical binding]; other site
1133853011977	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1133853011978	RNA/DNA hybrid binding site [nucleotide binding]; other site
1133853011979	active site
1133853011980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853011981	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1133853011982	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1133853011983	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853011984	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853011985	catalytic residue [active]
1133853011986	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853011987	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133853011988	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133853011989	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853011990	S-adenosylmethionine binding site [chemical binding]; other site
1133853011991	hypothetical protein; Provisional; Region: PRK05421
1133853011992	putative catalytic site [active]
1133853011993	putative metal binding site [ion binding]; other site
1133853011994	putative phosphate binding site [ion binding]; other site
1133853011995	putative catalytic site [active]
1133853011996	putative phosphate binding site [ion binding]; other site
1133853011997	putative metal binding site [ion binding]; other site
1133853011998	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133853011999	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853012000	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1133853012001	putative effector binding pocket; other site
1133853012002	dimerization interface [polypeptide binding]; other site
1133853012003	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133853012004	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1133853012005	active site
1133853012006	catalytic tetrad [active]
1133853012007	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1133853012008	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853012009	active site
1133853012010	motif I; other site
1133853012011	motif II; other site
1133853012012	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1133853012013	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1133853012014	Walker A/P-loop; other site
1133853012015	ATP binding site [chemical binding]; other site
1133853012016	Q-loop/lid; other site
1133853012017	ABC transporter signature motif; other site
1133853012018	Walker B; other site
1133853012019	D-loop; other site
1133853012020	H-loop/switch region; other site
1133853012021	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1133853012022	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853012023	dimer interface [polypeptide binding]; other site
1133853012024	conserved gate region; other site
1133853012025	ABC-ATPase subunit interface; other site
1133853012026	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1133853012027	lipoprotein, YaeC family; Region: TIGR00363
1133853012028	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1133853012029	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1133853012030	homodimer interaction site [polypeptide binding]; other site
1133853012031	cofactor binding site; other site
1133853012032	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1133853012033	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1133853012034	dimer interface [polypeptide binding]; other site
1133853012035	motif 1; other site
1133853012036	active site
1133853012037	motif 2; other site
1133853012038	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1133853012039	putative deacylase active site [active]
1133853012040	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1133853012041	active site
1133853012042	motif 3; other site
1133853012043	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1133853012044	anticodon binding site; other site
1133853012045	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1133853012046	hypothetical protein; Provisional; Region: PRK11479
1133853012047	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853012048	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853012049	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853012050	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1133853012051	NlpE N-terminal domain; Region: NlpE; pfam04170
1133853012052	hypothetical protein; Provisional; Region: PRK09256
1133853012053	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1133853012054	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1133853012055	hypothetical protein; Provisional; Region: PRK04964
1133853012056	Rho-binding antiterminator; Provisional; Region: PRK11625
1133853012057	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1133853012058	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1133853012059	Ligand Binding Site [chemical binding]; other site
1133853012060	TilS substrate binding domain; Region: TilS; pfam09179
1133853012061	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1133853012062	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1133853012063	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1133853012064	putative metal binding site [ion binding]; other site
1133853012065	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1133853012066	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133853012067	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133853012068	homodimer interface [polypeptide binding]; other site
1133853012069	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853012070	catalytic residue [active]
1133853012071	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133853012072	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1133853012073	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1133853012074	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1133853012075	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1133853012076	putative active site [active]
1133853012077	putative PHP Thumb interface [polypeptide binding]; other site
1133853012078	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1133853012079	generic binding surface II; other site
1133853012080	generic binding surface I; other site
1133853012081	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1133853012082	RNA/DNA hybrid binding site [nucleotide binding]; other site
1133853012083	active site
1133853012084	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1133853012085	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1133853012086	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1133853012087	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1133853012088	active site
1133853012089	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1133853012090	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1133853012091	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1133853012092	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1133853012093	trimer interface [polypeptide binding]; other site
1133853012094	active site
1133853012095	UDP-GlcNAc binding site [chemical binding]; other site
1133853012096	lipid binding site [chemical binding]; lipid-binding site
1133853012097	periplasmic chaperone; Provisional; Region: PRK10780
1133853012098	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1133853012099	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1133853012100	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133853012101	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133853012102	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133853012103	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133853012104	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133853012105	Surface antigen; Region: Bac_surface_Ag; pfam01103
1133853012106	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1133853012107	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1133853012108	active site
1133853012109	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1133853012110	protein binding site [polypeptide binding]; other site
1133853012111	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1133853012112	putative substrate binding region [chemical binding]; other site
1133853012113	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1133853012114	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1133853012115	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1133853012116	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1133853012117	catalytic residue [active]
1133853012118	putative FPP diphosphate  binding site; other site
1133853012119	putative FPP binding hydrophobic cleft; other site
1133853012120	dimer interface [polypeptide binding]; other site
1133853012121	putative IPP diphosphate binding site; other site
1133853012122	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1133853012123	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1133853012124	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1133853012125	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1133853012126	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1133853012127	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1133853012128	hinge region; other site
1133853012129	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1133853012130	putative nucleotide binding site [chemical binding]; other site
1133853012131	uridine monophosphate binding site [chemical binding]; other site
1133853012132	homohexameric interface [polypeptide binding]; other site
1133853012133	elongation factor Ts; Provisional; Region: tsf; PRK09377
1133853012134	UBA/TS-N domain; Region: UBA; pfam00627
1133853012135	Elongation factor TS; Region: EF_TS; pfam00889
1133853012136	Elongation factor TS; Region: EF_TS; pfam00889
1133853012137	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1133853012138	rRNA interaction site [nucleotide binding]; other site
1133853012139	S8 interaction site; other site
1133853012140	putative laminin-1 binding site; other site
1133853012141	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1133853012142	active site
1133853012143	PII uridylyl-transferase; Provisional; Region: PRK05007
1133853012144	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1133853012145	metal binding triad; other site
1133853012146	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1133853012147	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133853012148	Zn2+ binding site [ion binding]; other site
1133853012149	Mg2+ binding site [ion binding]; other site
1133853012150	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1133853012151	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1133853012152	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1133853012153	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1133853012154	trimer interface [polypeptide binding]; other site
1133853012155	active site
1133853012156	substrate binding site [chemical binding]; other site
1133853012157	CoA binding site [chemical binding]; other site
1133853012158	hypothetical protein; Provisional; Region: PRK13677
1133853012159	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1133853012160	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1133853012161	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1133853012162	serine endoprotease; Provisional; Region: PRK10942
1133853012163	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1133853012164	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133853012165	protein binding site [polypeptide binding]; other site
1133853012166	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133853012167	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1133853012168	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133853012169	Zn2+ binding site [ion binding]; other site
1133853012170	Mg2+ binding site [ion binding]; other site
1133853012171	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1133853012172	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1133853012173	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1133853012174	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1133853012175	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1133853012176	cobalamin binding residues [chemical binding]; other site
1133853012177	putative BtuC binding residues; other site
1133853012178	dimer interface [polypeptide binding]; other site
1133853012179	hypothetical protein; Provisional; Region: PRK10578
1133853012180	UPF0126 domain; Region: UPF0126; pfam03458
1133853012181	UPF0126 domain; Region: UPF0126; pfam03458
1133853012182	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1133853012183	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1133853012184	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1133853012185	Cl- selectivity filter; other site
1133853012186	Cl- binding residues [ion binding]; other site
1133853012187	pore gating glutamate residue; other site
1133853012188	dimer interface [polypeptide binding]; other site
1133853012189	H+/Cl- coupling transport residue; other site
1133853012190	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1133853012191	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133853012192	inhibitor-cofactor binding pocket; inhibition site
1133853012193	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853012194	catalytic residue [active]
1133853012195	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1133853012196	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853012197	ABC-ATPase subunit  interface; other site
1133853012198	dimer interface [polypeptide binding]; other site
1133853012199	putative PBP binding regions; other site
1133853012200	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853012201	ABC-ATPase subunit  interface; other site
1133853012202	dimer interface [polypeptide binding]; other site
1133853012203	putative PBP binding regions; other site
1133853012204	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1133853012205	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1133853012206	siderophore binding site; other site
1133853012207	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1133853012208	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133853012209	Walker A/P-loop; other site
1133853012210	ATP binding site [chemical binding]; other site
1133853012211	Q-loop/lid; other site
1133853012212	ABC transporter signature motif; other site
1133853012213	Walker B; other site
1133853012214	D-loop; other site
1133853012215	H-loop/switch region; other site
1133853012216	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1133853012217	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853012218	N-terminal plug; other site
1133853012219	ligand-binding site [chemical binding]; other site
1133853012220	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1133853012221	Transglycosylase; Region: Transgly; pfam00912
1133853012222	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1133853012223	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1133853012224	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853012225	ATP binding site [chemical binding]; other site
1133853012226	putative Mg++ binding site [ion binding]; other site
1133853012227	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853012228	nucleotide binding region [chemical binding]; other site
1133853012229	ATP-binding site [chemical binding]; other site
1133853012230	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
1133853012231	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1133853012232	2'-5' RNA ligase; Provisional; Region: PRK15124
1133853012233	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1133853012234	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1133853012235	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1133853012236	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1133853012237	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1133853012238	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
1133853012239	active site
1133853012240	nucleotide binding site [chemical binding]; other site
1133853012241	HIGH motif; other site
1133853012242	KMSKS motif; other site
1133853012243	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1133853012244	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1133853012245	active site
1133853012246	NTP binding site [chemical binding]; other site
1133853012247	metal binding triad [ion binding]; metal-binding site
1133853012248	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1133853012249	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1133853012250	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1133853012251	catalytic center binding site [active]
1133853012252	ATP binding site [chemical binding]; other site
1133853012253	Fimbrial protein; Region: Fimbrial; cl01416
1133853012254	putative chaperone protein EcpD; Provisional; Region: PRK09926
1133853012255	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853012256	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853012257	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1133853012258	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853012259	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853012260	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853012261	Fimbrial protein; Region: Fimbrial; cl01416
1133853012262	putative fimbrial protein StaE; Provisional; Region: PRK15263
1133853012263	putative fimbrial protein StaF; Provisional; Region: PRK15262
1133853012264	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
1133853012265	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1133853012266	oligomerization interface [polypeptide binding]; other site
1133853012267	active site
1133853012268	metal binding site [ion binding]; metal-binding site
1133853012269	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1133853012270	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1133853012271	active site
1133853012272	ATP-binding site [chemical binding]; other site
1133853012273	pantoate-binding site; other site
1133853012274	HXXH motif; other site
1133853012275	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1133853012276	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133853012277	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1133853012278	tetramerization interface [polypeptide binding]; other site
1133853012279	active site
1133853012280	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1133853012281	putative active site [active]
1133853012282	putative metal binding site [ion binding]; other site
1133853012283	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1133853012284	active pocket/dimerization site; other site
1133853012285	active site
1133853012286	phosphorylation site [posttranslational modification]
1133853012287	inner membrane transport permease; Provisional; Region: PRK15066
1133853012288	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133853012289	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1133853012290	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133853012291	Walker A/P-loop; other site
1133853012292	ATP binding site [chemical binding]; other site
1133853012293	Q-loop/lid; other site
1133853012294	ABC transporter signature motif; other site
1133853012295	Walker B; other site
1133853012296	D-loop; other site
1133853012297	H-loop/switch region; other site
1133853012298	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1133853012299	active site clefts [active]
1133853012300	zinc binding site [ion binding]; other site
1133853012301	dimer interface [polypeptide binding]; other site
1133853012302	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133853012303	active site
1133853012304	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1133853012305	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1133853012306	Trp docking motif [polypeptide binding]; other site
1133853012307	putative active site [active]
1133853012308	multicopper oxidase; Provisional; Region: PRK10965
1133853012309	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1133853012310	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1133853012311	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1133853012312	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1133853012313	spermidine synthase; Provisional; Region: PRK00811
1133853012314	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853012315	S-adenosylmethionine binding site [chemical binding]; other site
1133853012316	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1133853012317	hypothetical protein; Provisional; Region: PRK05248
1133853012318	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1133853012319	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1133853012320	substrate binding site [chemical binding]; other site
1133853012321	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1133853012322	substrate binding site [chemical binding]; other site
1133853012323	ligand binding site [chemical binding]; other site
1133853012324	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1133853012325	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
1133853012326	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1133853012327	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1133853012328	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853012329	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1133853012330	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1133853012331	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133853012332	E3 interaction surface; other site
1133853012333	lipoyl attachment site [posttranslational modification]; other site
1133853012334	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133853012335	E3 interaction surface; other site
1133853012336	lipoyl attachment site [posttranslational modification]; other site
1133853012337	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133853012338	E3 interaction surface; other site
1133853012339	lipoyl attachment site [posttranslational modification]; other site
1133853012340	e3 binding domain; Region: E3_binding; pfam02817
1133853012341	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1133853012342	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1133853012343	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1133853012344	dimer interface [polypeptide binding]; other site
1133853012345	TPP-binding site [chemical binding]; other site
1133853012346	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1133853012347	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853012348	DNA-binding site [nucleotide binding]; DNA binding site
1133853012349	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853012350	aromatic amino acid transporter; Provisional; Region: PRK10238
1133853012351	regulatory protein AmpE; Provisional; Region: PRK10987
1133853012352	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1133853012353	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1133853012354	amidase catalytic site [active]
1133853012355	Zn binding residues [ion binding]; other site
1133853012356	substrate binding site [chemical binding]; other site
1133853012357	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1133853012358	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1133853012359	dimerization interface [polypeptide binding]; other site
1133853012360	active site
1133853012361	putative major pilin subunit; Provisional; Region: PRK10574
1133853012362	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1133853012363	Pilin (bacterial filament); Region: Pilin; pfam00114
1133853012364	hypothetical protein; Provisional; Region: PRK10436
1133853012365	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1133853012366	Walker A motif; other site
1133853012367	ATP binding site [chemical binding]; other site
1133853012368	Walker B motif; other site
1133853012369	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1133853012370	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133853012371	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133853012372	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1133853012373	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1133853012374	active site
1133853012375	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1133853012376	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1133853012377	CoA-binding site [chemical binding]; other site
1133853012378	ATP-binding [chemical binding]; other site
1133853012379	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1133853012380	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1133853012381	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1133853012382	active site
1133853012383	8-oxo-dGMP binding site [chemical binding]; other site
1133853012384	nudix motif; other site
1133853012385	metal binding site [ion binding]; metal-binding site
1133853012386	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1133853012387	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1133853012388	SEC-C motif; Region: SEC-C; pfam02810
1133853012389	SecA regulator SecM; Provisional; Region: PRK02943
1133853012390	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1133853012391	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1133853012392	cell division protein FtsZ; Validated; Region: PRK09330
1133853012393	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1133853012394	nucleotide binding site [chemical binding]; other site
1133853012395	SulA interaction site; other site
1133853012396	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1133853012397	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133853012398	Cell division protein FtsA; Region: FtsA; pfam14450
1133853012399	cell division protein FtsQ; Provisional; Region: PRK10775
1133853012400	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1133853012401	Cell division protein FtsQ; Region: FtsQ; pfam03799
1133853012402	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1133853012403	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1133853012404	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1133853012405	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1133853012406	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133853012407	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133853012408	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133853012409	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1133853012410	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1133853012411	active site
1133853012412	homodimer interface [polypeptide binding]; other site
1133853012413	cell division protein FtsW; Provisional; Region: PRK10774
1133853012414	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1133853012415	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133853012416	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133853012417	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1133853012418	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1133853012419	Mg++ binding site [ion binding]; other site
1133853012420	putative catalytic motif [active]
1133853012421	putative substrate binding site [chemical binding]; other site
1133853012422	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1133853012423	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133853012424	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133853012425	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133853012426	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1133853012427	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133853012428	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133853012429	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133853012430	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1133853012431	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1133853012432	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1133853012433	cell division protein FtsL; Provisional; Region: PRK10772
1133853012434	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1133853012435	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1133853012436	mraZ protein; Region: TIGR00242
1133853012437	MraZ protein; Region: MraZ; pfam02381
1133853012438	MraZ protein; Region: MraZ; pfam02381
1133853012439	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1133853012440	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853012441	DNA binding site [nucleotide binding]
1133853012442	domain linker motif; other site
1133853012443	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1133853012444	dimerization interface [polypeptide binding]; other site
1133853012445	ligand binding site [chemical binding]; other site
1133853012446	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1133853012447	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1133853012448	putative valine binding site [chemical binding]; other site
1133853012449	dimer interface [polypeptide binding]; other site
1133853012450	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1133853012451	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1133853012452	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133853012453	PYR/PP interface [polypeptide binding]; other site
1133853012454	dimer interface [polypeptide binding]; other site
1133853012455	TPP binding site [chemical binding]; other site
1133853012456	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133853012457	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1133853012458	TPP-binding site [chemical binding]; other site
1133853012459	dimer interface [polypeptide binding]; other site
1133853012460	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1133853012461	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853012462	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1133853012463	putative substrate binding pocket [chemical binding]; other site
1133853012464	putative dimerization interface [polypeptide binding]; other site
1133853012465	leu operon leader peptide; Provisional; Region: PRK09925
1133853012466	2-isopropylmalate synthase; Validated; Region: PRK00915
1133853012467	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1133853012468	active site
1133853012469	catalytic residues [active]
1133853012470	metal binding site [ion binding]; metal-binding site
1133853012471	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1133853012472	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1133853012473	tartrate dehydrogenase; Region: TTC; TIGR02089
1133853012474	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1133853012475	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1133853012476	substrate binding site [chemical binding]; other site
1133853012477	ligand binding site [chemical binding]; other site
1133853012478	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1133853012479	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1133853012480	substrate binding site [chemical binding]; other site
1133853012481	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853012482	sugar efflux transporter; Region: 2A0120; TIGR00899
1133853012483	putative substrate translocation pore; other site
1133853012484	transcriptional regulator SgrR; Provisional; Region: PRK13626
1133853012485	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1133853012486	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1133853012487	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1133853012488	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1133853012489	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1133853012490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853012491	dimer interface [polypeptide binding]; other site
1133853012492	conserved gate region; other site
1133853012493	putative PBP binding loops; other site
1133853012494	ABC-ATPase subunit interface; other site
1133853012495	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853012496	dimer interface [polypeptide binding]; other site
1133853012497	conserved gate region; other site
1133853012498	putative PBP binding loops; other site
1133853012499	ABC-ATPase subunit interface; other site
1133853012500	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1133853012501	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1133853012502	Walker A/P-loop; other site
1133853012503	ATP binding site [chemical binding]; other site
1133853012504	Q-loop/lid; other site
1133853012505	ABC transporter signature motif; other site
1133853012506	Walker B; other site
1133853012507	D-loop; other site
1133853012508	H-loop/switch region; other site
1133853012509	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133853012510	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1133853012511	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1133853012512	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133853012513	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853012514	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853012515	ribulokinase; Provisional; Region: PRK04123
1133853012516	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1133853012517	N- and C-terminal domain interface [polypeptide binding]; other site
1133853012518	active site
1133853012519	MgATP binding site [chemical binding]; other site
1133853012520	catalytic site [active]
1133853012521	metal binding site [ion binding]; metal-binding site
1133853012522	carbohydrate binding site [chemical binding]; other site
1133853012523	homodimer interface [polypeptide binding]; other site
1133853012524	L-arabinose isomerase; Provisional; Region: PRK02929
1133853012525	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1133853012526	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1133853012527	trimer interface [polypeptide binding]; other site
1133853012528	putative substrate binding site [chemical binding]; other site
1133853012529	putative metal binding site [ion binding]; other site
1133853012530	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1133853012531	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133853012532	intersubunit interface [polypeptide binding]; other site
1133853012533	active site
1133853012534	Zn2+ binding site [ion binding]; other site
1133853012535	DNA polymerase II; Reviewed; Region: PRK05762
1133853012536	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1133853012537	active site
1133853012538	catalytic site [active]
1133853012539	substrate binding site [chemical binding]; other site
1133853012540	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1133853012541	active site
1133853012542	metal-binding site
1133853012543	ATP-dependent helicase HepA; Validated; Region: PRK04914
1133853012544	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853012545	ATP binding site [chemical binding]; other site
1133853012546	putative Mg++ binding site [ion binding]; other site
1133853012547	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853012548	nucleotide binding region [chemical binding]; other site
1133853012549	ATP-binding site [chemical binding]; other site
1133853012550	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1133853012551	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1133853012552	active site
1133853012553	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1133853012554	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1133853012555	putative metal binding site [ion binding]; other site
1133853012556	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133853012557	HSP70 interaction site [polypeptide binding]; other site
1133853012558	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1133853012559	OstA-like protein; Region: OstA; pfam03968
1133853012560	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1133853012561	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1133853012562	SurA N-terminal domain; Region: SurA_N; pfam09312
1133853012563	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1133853012564	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1133853012565	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1133853012566	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1133853012567	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1133853012568	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1133853012569	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1133853012570	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1133853012571	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1133853012572	active site
1133853012573	metal binding site [ion binding]; metal-binding site
1133853012574	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1133853012575	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1133853012576	folate binding site [chemical binding]; other site
1133853012577	NADP+ binding site [chemical binding]; other site
1133853012578	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1133853012579	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1133853012580	TrkA-N domain; Region: TrkA_N; pfam02254
1133853012581	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1133853012582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853012583	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1133853012584	putative substrate translocation pore; other site
1133853012585	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1133853012586	putative oxidoreductase FixC; Provisional; Region: PRK10157
1133853012587	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1133853012588	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
1133853012589	Ligand binding site [chemical binding]; other site
1133853012590	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1133853012591	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1133853012592	Ligand binding site [chemical binding]; other site
1133853012593	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1133853012594	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1133853012595	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1133853012596	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1133853012597	active site
1133853012598	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1133853012599	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1133853012600	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1133853012601	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1133853012602	acyl-activating enzyme (AAE) consensus motif; other site
1133853012603	putative AMP binding site [chemical binding]; other site
1133853012604	putative active site [active]
1133853012605	putative CoA binding site [chemical binding]; other site
1133853012606	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1133853012607	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853012608	substrate binding site [chemical binding]; other site
1133853012609	oxyanion hole (OAH) forming residues; other site
1133853012610	trimer interface [polypeptide binding]; other site
1133853012611	carnitine operon protein CaiE; Provisional; Region: PRK13627
1133853012612	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1133853012613	putative trimer interface [polypeptide binding]; other site
1133853012614	putative metal binding site [ion binding]; other site
1133853012615	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1133853012616	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1133853012617	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1133853012618	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1133853012619	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1133853012620	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1133853012621	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1133853012622	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1133853012623	IMP binding site; other site
1133853012624	dimer interface [polypeptide binding]; other site
1133853012625	interdomain contacts; other site
1133853012626	partial ornithine binding site; other site
1133853012627	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1133853012628	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1133853012629	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1133853012630	catalytic site [active]
1133853012631	subunit interface [polypeptide binding]; other site
1133853012632	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1133853012633	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1133853012634	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1133853012635	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1133853012636	active site
1133853012637	tetramer interface [polypeptide binding]; other site
1133853012638	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1133853012639	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1133853012640	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1133853012641	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133853012642	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1133853012643	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1133853012644	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1133853012645	HIGH motif; other site
1133853012646	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1133853012647	active site
1133853012648	KMSKS motif; other site
1133853012649	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1133853012650	tRNA binding surface [nucleotide binding]; other site
1133853012651	anticodon binding site; other site
1133853012652	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1133853012653	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1133853012654	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1133853012655	active site
1133853012656	Riboflavin kinase; Region: Flavokinase; smart00904
1133853012657	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1133853012658	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1133853012659	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853012660	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853012661	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1133853012662	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853012663	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1133853012664	putative dimerization interface [polypeptide binding]; other site
1133853012665	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1133853012666	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
1133853012667	Hok/gef family; Region: HOK_GEF; pfam01848
1133853012668	chaperone protein DnaJ; Provisional; Region: PRK10767
1133853012669	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133853012670	HSP70 interaction site [polypeptide binding]; other site
1133853012671	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1133853012672	substrate binding site [polypeptide binding]; other site
1133853012673	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1133853012674	Zn binding sites [ion binding]; other site
1133853012675	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1133853012676	dimer interface [polypeptide binding]; other site
1133853012677	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1133853012678	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
1133853012679	nucleotide binding site [chemical binding]; other site
1133853012680	NEF interaction site [polypeptide binding]; other site
1133853012681	SBD interface [polypeptide binding]; other site
1133853012682	hypothetical protein; Provisional; Region: PRK10154
1133853012683	hypothetical protein; Provisional; Region: PRK10236
1133853012684	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1133853012685	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1133853012686	hypothetical protein; Provisional; Region: PRK10659
1133853012687	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1133853012688	MPT binding site; other site
1133853012689	trimer interface [polypeptide binding]; other site
1133853012690	transaldolase-like protein; Provisional; Region: PTZ00411
1133853012691	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1133853012692	active site
1133853012693	dimer interface [polypeptide binding]; other site
1133853012694	catalytic residue [active]
1133853012695	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1133853012696	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1133853012697	hypothetical protein; Validated; Region: PRK02101
1133853012698	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1133853012699	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1133853012700	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1133853012701	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853012702	catalytic residue [active]
1133853012703	homoserine kinase; Region: thrB; TIGR00191
1133853012704	Protein of unknown function; Region: YhfT; pfam10797
1133853012705	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1133853012706	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1133853012707	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1133853012708	putative catalytic residues [active]
1133853012709	putative nucleotide binding site [chemical binding]; other site
1133853012710	putative aspartate binding site [chemical binding]; other site
1133853012711	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1133853012712	dimer interface [polypeptide binding]; other site
1133853012713	putative threonine allosteric regulatory site; other site
1133853012714	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1133853012715	putative threonine allosteric regulatory site; other site
1133853012716	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1133853012717	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1133853012718	putative RNA methyltransferase; Provisional; Region: PRK10433
1133853012719	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
1133853012720	two-component response regulator; Provisional; Region: PRK11173
1133853012721	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853012722	active site
1133853012723	phosphorylation site [posttranslational modification]
1133853012724	intermolecular recognition site; other site
1133853012725	dimerization interface [polypeptide binding]; other site
1133853012726	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853012727	DNA binding site [nucleotide binding]
1133853012728	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1133853012729	sensory histidine kinase CreC; Provisional; Region: PRK11100
1133853012730	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853012731	dimerization interface [polypeptide binding]; other site
1133853012732	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853012733	dimer interface [polypeptide binding]; other site
1133853012734	phosphorylation site [posttranslational modification]
1133853012735	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853012736	ATP binding site [chemical binding]; other site
1133853012737	Mg2+ binding site [ion binding]; other site
1133853012738	G-X-G motif; other site
1133853012739	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1133853012740	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853012741	active site
1133853012742	phosphorylation site [posttranslational modification]
1133853012743	intermolecular recognition site; other site
1133853012744	dimerization interface [polypeptide binding]; other site
1133853012745	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853012746	DNA binding site [nucleotide binding]
1133853012747	hypothetical protein; Provisional; Region: PRK10756
1133853012748	CreA protein; Region: CreA; pfam05981
1133853012749	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1133853012750	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853012751	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1133853012752	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133853012753	catalytic core [active]
1133853012754	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1133853012755	Trp operon repressor; Provisional; Region: PRK01381
1133853012756	lytic murein transglycosylase; Provisional; Region: PRK11619
1133853012757	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853012758	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853012759	catalytic residue [active]
1133853012760	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1133853012761	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133853012762	Walker A/P-loop; other site
1133853012763	ATP binding site [chemical binding]; other site
1133853012764	Q-loop/lid; other site
1133853012765	ABC transporter signature motif; other site
1133853012766	Walker B; other site
1133853012767	D-loop; other site
1133853012768	H-loop/switch region; other site
1133853012769	ABC transporter; Region: ABC_tran_2; pfam12848
1133853012770	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133853012771	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853012772	non-specific DNA binding site [nucleotide binding]; other site
1133853012773	salt bridge; other site
1133853012774	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1133853012775	sequence-specific DNA binding site [nucleotide binding]; other site
1133853012776	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1133853012777	active site
1133853012778	(T/H)XGH motif; other site
1133853012779	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1133853012780	DNA repair protein RadA; Region: sms; TIGR00416
1133853012781	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1133853012782	Walker A motif/ATP binding site; other site
1133853012783	ATP binding site [chemical binding]; other site
1133853012784	Walker B motif; other site
1133853012785	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1133853012786	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1133853012787	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853012788	motif II; other site
1133853012789	hypothetical protein; Provisional; Region: PRK11246
1133853012790	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1133853012791	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1133853012792	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1133853012793	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1133853012794	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1133853012795	phosphopentomutase; Provisional; Region: PRK05362
1133853012796	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1133853012797	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1133853012798	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1133853012799	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1133853012800	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1133853012801	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1133853012802	intersubunit interface [polypeptide binding]; other site
1133853012803	active site
1133853012804	catalytic residue [active]
1133853012805	hypothetical protein; Provisional; Region: PRK10977
1133853012806	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1133853012807	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1133853012808	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853012809	FeS/SAM binding site; other site
1133853012810	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1133853012811	active site
1133853012812	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1133853012813	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1133853012814	active site
1133853012815	nucleophile elbow; other site
1133853012816	periplasmic protein; Provisional; Region: PRK10568
1133853012817	BON domain; Region: BON; pfam04972
1133853012818	BON domain; Region: BON; pfam04972
1133853012819	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1133853012820	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1133853012821	G1 box; other site
1133853012822	putative GEF interaction site [polypeptide binding]; other site
1133853012823	GTP/Mg2+ binding site [chemical binding]; other site
1133853012824	Switch I region; other site
1133853012825	G2 box; other site
1133853012826	G3 box; other site
1133853012827	Switch II region; other site
1133853012828	G4 box; other site
1133853012829	G5 box; other site
1133853012830	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1133853012831	dUMP phosphatase; Provisional; Region: PRK09449
1133853012832	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853012833	motif II; other site
1133853012834	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1133853012835	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853012836	Coenzyme A binding pocket [chemical binding]; other site
1133853012837	DNA polymerase III subunit psi; Validated; Region: PRK06856
1133853012838	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1133853012839	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1133853012840	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853012841	S-adenosylmethionine binding site [chemical binding]; other site
1133853012842	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1133853012843	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1133853012844	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1133853012845	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1133853012846	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1133853012847	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853012848	DNA binding residues [nucleotide binding]
1133853012849	dimerization interface [polypeptide binding]; other site
1133853012850	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133853012851	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133853012852	DNA binding residues [nucleotide binding]
1133853012853	dimerization interface [polypeptide binding]; other site
1133853012854	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1133853012855	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1133853012856	hypothetical protein; Provisional; Region: PRK09917
1133853012857	primosomal protein DnaI; Provisional; Region: PRK02854
1133853012858	DNA replication protein DnaC; Validated; Region: PRK07952
1133853012859	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853012860	Walker A motif; other site
1133853012861	ATP binding site [chemical binding]; other site
1133853012862	Walker B motif; other site
1133853012863	hypothetical protein; Provisional; Region: PRK11667
1133853012864	phosphoglycerol transferase I; Provisional; Region: PRK03776
1133853012865	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1133853012866	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133853012867	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1133853012868	putative NAD(P) binding site [chemical binding]; other site
1133853012869	catalytic Zn binding site [ion binding]; other site
1133853012870	structural Zn binding site [ion binding]; other site
1133853012871	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853012872	DNA-binding site [nucleotide binding]; DNA binding site
1133853012873	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1133853012874	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1133853012875	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853012876	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853012877	D-galactonate transporter; Region: 2A0114; TIGR00893
1133853012878	putative substrate translocation pore; other site
1133853012879	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1133853012880	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133853012881	dimer interface [polypeptide binding]; other site
1133853012882	ligand binding site [chemical binding]; other site
1133853012883	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853012884	dimerization interface [polypeptide binding]; other site
1133853012885	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133853012886	dimer interface [polypeptide binding]; other site
1133853012887	putative CheW interface [polypeptide binding]; other site
1133853012888	carbon starvation protein A; Provisional; Region: PRK15015
1133853012889	Carbon starvation protein CstA; Region: CstA; pfam02554
1133853012890	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1133853012891	Uncharacterized small protein [Function unknown]; Region: COG2879
1133853012892	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1133853012893	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1133853012894	P-loop, Walker A motif; other site
1133853012895	Base recognition motif; other site
1133853012896	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1133853012897	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1133853012898	Protein of unknown function DUF262; Region: DUF262; pfam03235
1133853012899	Protein of unknown function DUF262; Region: DUF262; pfam03235
1133853012900	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1133853012901	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1133853012902	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1133853012903	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853012904	ATP binding site [chemical binding]; other site
1133853012905	putative Mg++ binding site [ion binding]; other site
1133853012906	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1133853012907	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1133853012908	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1133853012909	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1133853012910	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1133853012911	endoribonuclease SymE; Provisional; Region: PRK13605
1133853012912	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1133853012913	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1133853012914	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853012915	DNA-binding site [nucleotide binding]; DNA binding site
1133853012916	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853012917	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853012918	homodimer interface [polypeptide binding]; other site
1133853012919	catalytic residue [active]
1133853012920	putative transposase; Provisional; Region: PRK09857
1133853012921	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133853012922	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1133853012923	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853012924	putative substrate translocation pore; other site
1133853012925	Predicted membrane protein [Function unknown]; Region: COG2733
1133853012926	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
1133853012927	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1133853012928	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1133853012929	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
1133853012930	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1133853012931	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1133853012932	SdiA-regulated; Region: SdiA-regulated; cd09971
1133853012933	putative active site [active]
1133853012934	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853012935	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853012936	putative substrate translocation pore; other site
1133853012937	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1133853012938	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1133853012939	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1133853012940	Nucleoside recognition; Region: Gate; pfam07670
1133853012941	hypothetical protein; Provisional; Region: PRK10519
1133853012942	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
1133853012943	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
1133853012944	dimer interface [polypeptide binding]; other site
1133853012945	active site
1133853012946	cell density-dependent motility repressor; Provisional; Region: PRK10082
1133853012947	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853012948	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133853012949	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1133853012950	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
1133853012951	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1133853012952	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853012953	DNA-binding site [nucleotide binding]; DNA binding site
1133853012954	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853012955	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1133853012956	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133853012957	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133853012958	mannonate dehydratase; Region: uxuA; TIGR00695
1133853012959	mannonate dehydratase; Provisional; Region: PRK03906
1133853012960	fructuronate transporter; Provisional; Region: PRK10034
1133853012961	gluconate transporter; Region: gntP; TIGR00791
1133853012962	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853012963	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853012964	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853012965	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853012966	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133853012967	Haemolysin expression modulating protein; Region: HHA; pfam05321
1133853012968	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133853012969	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853012970	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133853012971	Transposase; Region: HTH_Tnp_1; pfam01527
1133853012972	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853012973	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853012974	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853012975	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
1133853012976	homodimer interface [polypeptide binding]; other site
1133853012977	putative GKAP docking site [polypeptide binding]; other site
1133853012978	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853012979	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853012980	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853012981	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853012982	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853012983	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
1133853012984	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
1133853012985	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133853012986	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133853012987	DNA binding residues [nucleotide binding]
1133853012988	fec operon regulator FecR; Reviewed; Region: PRK09774
1133853012989	FecR protein; Region: FecR; pfam04773
1133853012990	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1133853012991	Secretin and TonB N terminus short domain; Region: STN; smart00965
1133853012992	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853012993	N-terminal plug; other site
1133853012994	ligand-binding site [chemical binding]; other site
1133853012995	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
1133853012996	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1133853012997	siderophore binding site; other site
1133853012998	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1133853012999	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853013000	dimer interface [polypeptide binding]; other site
1133853013001	ABC-ATPase subunit  interface; other site
1133853013002	putative PBP binding regions; other site
1133853013003	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1133853013004	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133853013005	ABC-ATPase subunit  interface; other site
1133853013006	dimer interface [polypeptide binding]; other site
1133853013007	putative PBP binding regions; other site
1133853013008	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
1133853013009	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133853013010	Walker A/P-loop; other site
1133853013011	ATP binding site [chemical binding]; other site
1133853013012	Q-loop/lid; other site
1133853013013	ABC transporter signature motif; other site
1133853013014	Walker B; other site
1133853013015	D-loop; other site
1133853013016	H-loop/switch region; other site
1133853013017	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1133853013018	similar to transposase ORF B (fragment), IS911
1133853013019	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133853013020	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133853013021	putative active site [active]
1133853013022	putative NTP binding site [chemical binding]; other site
1133853013023	putative nucleic acid binding site [nucleotide binding]; other site
1133853013024	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133853013025	HTH-like domain; Region: HTH_21; pfam13276
1133853013026	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853013027	Transposase; Region: HTH_Tnp_1; cl17663
1133853013028	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1133853013029	putative active site [active]
1133853013030	putative metal binding site [ion binding]; other site
1133853013031	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1133853013032	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1133853013033	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1133853013034	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1133853013035	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133853013036	putative acyl-acceptor binding pocket; other site
1133853013037	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133853013038	Integrase core domain; Region: rve; pfam00665
1133853013039	Integrase core domain; Region: rve_3; pfam13683
1133853013040	BCCT family transporter; Region: BCCT; cl00569
1133853013041	Predicted membrane protein [Function unknown]; Region: COG4325
1133853013042	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
1133853013043	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133853013044	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853013045	similar to Protein yhdH (fragment); COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
1133853013046	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853013047	Transposase; Region: HTH_Tnp_1; pfam01527
1133853013048	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853013049	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853013050	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853013051	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853013052	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853013053	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853013054	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1133853013055	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1133853013056	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1133853013057	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853013058	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853013059	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1133853013060	substrate binding site [chemical binding]; other site
1133853013061	dimer interface [polypeptide binding]; other site
1133853013062	ATP binding site [chemical binding]; other site
1133853013063	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1133853013064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853013065	putative substrate translocation pore; other site
1133853013066	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1133853013067	active site
1133853013068	catalytic residues [active]
1133853013069	similar to transposase ORF1, IS3 family (fragment); COG2963 Transposase and inactivated derivatives
1133853013070	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1133853013071	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1133853013072	active site
1133853013073	P-loop; other site
1133853013074	phosphorylation site [posttranslational modification]
1133853013075	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853013076	active site
1133853013077	phosphorylation site [posttranslational modification]
1133853013078	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133853013079	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853013080	DNA binding site [nucleotide binding]
1133853013081	domain linker motif; other site
1133853013082	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1133853013083	putative dimerization interface [polypeptide binding]; other site
1133853013084	putative ligand binding site [chemical binding]; other site
1133853013085	similar to transposase (fragment), IS110 family protein; COG0443 Molecular chaperone
1133853013086	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1133853013087	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1133853013088	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1133853013089	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1133853013090	putative active site cavity [active]
1133853013091	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1133853013092	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133853013093	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853013094	active site turn [active]
1133853013095	phosphorylation site [posttranslational modification]
1133853013096	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1133853013097	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133853013098	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133853013099	putative active site [active]
1133853013100	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853013101	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853013102	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853013103	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853013104	Fic family protein [Function unknown]; Region: COG3177
1133853013105	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
1133853013106	Fic/DOC family; Region: Fic; pfam02661
1133853013107	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853013108	salt bridge; other site
1133853013109	non-specific DNA binding site [nucleotide binding]; other site
1133853013110	sequence-specific DNA binding site [nucleotide binding]; other site
1133853013111	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853013112	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853013113	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853013114	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853013115	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1133853013116	HNH endonuclease; Region: HNH_2; pfam13391
1133853013117	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1133853013118	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1133853013119	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1133853013120	Putative helicase; Region: TraI_2; pfam07514
1133853013121	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
1133853013122	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1133853013123	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
1133853013124	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1133853013125	active site
1133853013126	catalytic residues [active]
1133853013127	DNA binding site [nucleotide binding]
1133853013128	Int/Topo IB signature motif; other site
1133853013129	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1133853013130	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1133853013131	putative NAD(P) binding site [chemical binding]; other site
1133853013132	putative substrate binding site [chemical binding]; other site
1133853013133	catalytic Zn binding site [ion binding]; other site
1133853013134	structural Zn binding site [ion binding]; other site
1133853013135	dimer interface [polypeptide binding]; other site
1133853013136	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1133853013137	ATP-binding site [chemical binding]; other site
1133853013138	Gluconate-6-phosphate binding site [chemical binding]; other site
1133853013139	Shikimate kinase; Region: SKI; pfam01202
1133853013140	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1133853013141	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1133853013142	putative NAD(P) binding site [chemical binding]; other site
1133853013143	catalytic Zn binding site [ion binding]; other site
1133853013144	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1133853013145	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1133853013146	NADP binding site [chemical binding]; other site
1133853013147	homodimer interface [polypeptide binding]; other site
1133853013148	active site
1133853013149	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1133853013150	gluconate transporter; Region: gntP; TIGR00791
1133853013151	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1133853013152	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853013153	DNA binding site [nucleotide binding]
1133853013154	domain linker motif; other site
1133853013155	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1133853013156	putative dimerization interface [polypeptide binding]; other site
1133853013157	putative ligand binding site [chemical binding]; other site
1133853013158	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1133853013159	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1133853013160	Walker A motif; other site
1133853013161	ATP binding site [chemical binding]; other site
1133853013162	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1133853013163	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1133853013164	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1133853013165	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1133853013166	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1133853013167	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1133853013168	interface (dimer of trimers) [polypeptide binding]; other site
1133853013169	Substrate-binding/catalytic site; other site
1133853013170	Zn-binding sites [ion binding]; other site
1133853013171	DNA polymerase III subunit chi; Validated; Region: PRK05728
1133853013172	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1133853013173	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1133853013174	HIGH motif; other site
1133853013175	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1133853013176	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1133853013177	active site
1133853013178	KMSKS motif; other site
1133853013179	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1133853013180	tRNA binding surface [nucleotide binding]; other site
1133853013181	anticodon binding site; other site
1133853013182	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1133853013183	Predicted membrane protein [Function unknown]; Region: COG4269
1133853013184	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1133853013185	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853013186	Coenzyme A binding pocket [chemical binding]; other site
1133853013187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1133853013188	RNase E inhibitor protein; Provisional; Region: PRK11191
1133853013189	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1133853013190	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1133853013191	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1133853013192	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853013193	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853013194	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853013195	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133853013196	SopA-like central domain; Region: SopA; pfam13981
1133853013197	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1133853013198	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133853013199	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853013200	oxidoreductase; Provisional; Region: PRK12742
1133853013201	classical (c) SDRs; Region: SDR_c; cd05233
1133853013202	NAD(P) binding site [chemical binding]; other site
1133853013203	active site
1133853013204	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1133853013205	homotrimer interaction site [polypeptide binding]; other site
1133853013206	putative active site [active]
1133853013207	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
1133853013208	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
1133853013209	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1133853013210	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1133853013211	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1133853013212	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1133853013213	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1133853013214	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1133853013215	homotrimer interaction site [polypeptide binding]; other site
1133853013216	putative active site [active]
1133853013217	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853013218	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853013219	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853013220	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1133853013221	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1133853013222	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133853013223	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1133853013224	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853013225	motif II; other site
1133853013226	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1133853013227	trehalose repressor; Provisional; Region: treR; PRK09492
1133853013228	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853013229	DNA binding site [nucleotide binding]
1133853013230	domain linker motif; other site
1133853013231	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1133853013232	dimerization interface [polypeptide binding]; other site
1133853013233	ligand binding site [chemical binding]; other site
1133853013234	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1133853013235	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853013236	active site turn [active]
1133853013237	phosphorylation site [posttranslational modification]
1133853013238	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133853013239	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1133853013240	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1133853013241	Ca binding site [ion binding]; other site
1133853013242	active site
1133853013243	catalytic site [active]
1133853013244	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1133853013245	ATP cone domain; Region: ATP-cone; pfam03477
1133853013246	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1133853013247	effector binding site; other site
1133853013248	active site
1133853013249	Zn binding site [ion binding]; other site
1133853013250	glycine loop; other site
1133853013251	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1133853013252	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853013253	FeS/SAM binding site; other site
1133853013254	cytochrome b562; Provisional; Region: PRK15058
1133853013255	peptidase PmbA; Provisional; Region: PRK11040
1133853013256	hypothetical protein; Provisional; Region: PRK05255
1133853013257	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1133853013258	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133853013259	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133853013260	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133853013261	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1133853013262	AMP binding site [chemical binding]; other site
1133853013263	metal binding site [ion binding]; metal-binding site
1133853013264	active site
1133853013265	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853013266	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853013267	TM-ABC transporter signature motif; other site
1133853013268	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853013269	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853013270	TM-ABC transporter signature motif; other site
1133853013271	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1133853013272	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853013273	Walker A/P-loop; other site
1133853013274	ATP binding site [chemical binding]; other site
1133853013275	Q-loop/lid; other site
1133853013276	ABC transporter signature motif; other site
1133853013277	Walker B; other site
1133853013278	D-loop; other site
1133853013279	H-loop/switch region; other site
1133853013280	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853013281	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1133853013282	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1133853013283	putative ligand binding site [chemical binding]; other site
1133853013284	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1133853013285	dimer interface [polypeptide binding]; other site
1133853013286	substrate binding site [chemical binding]; other site
1133853013287	metal binding sites [ion binding]; metal-binding site
1133853013288	toxin ChpB; Provisional; Region: PRK09812
1133853013289	antitoxin ChpS; Provisional; Region: PRK11347
1133853013290	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1133853013291	putative active site pocket [active]
1133853013292	dimerization interface [polypeptide binding]; other site
1133853013293	putative catalytic residue [active]
1133853013294	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1133853013295	Family of unknown function (DUF490); Region: DUF490; pfam04357
1133853013296	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1133853013297	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133853013298	Surface antigen; Region: Bac_surface_Ag; pfam01103
1133853013299	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1133853013300	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1133853013301	Domain of unknown function DUF21; Region: DUF21; pfam01595
1133853013302	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133853013303	Transporter associated domain; Region: CorC_HlyC; smart01091
1133853013304	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1133853013305	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1133853013306	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1133853013307	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1133853013308	active site
1133853013309	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1133853013310	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1133853013311	active site
1133853013312	metal binding site [ion binding]; metal-binding site
1133853013313	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1133853013314	Predicted transcriptional regulators [Transcription]; Region: COG1733
1133853013315	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1133853013316	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1133853013317	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1133853013318	NADP binding site [chemical binding]; other site
1133853013319	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1133853013320	EamA-like transporter family; Region: EamA; pfam00892
1133853013321	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1133853013322	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1133853013323	Hemerythrin-like domain; Region: Hr-like; cd12108
1133853013324	Fe binding site [ion binding]; other site
1133853013325	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1133853013326	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1133853013327	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1133853013328	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133853013329	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1133853013330	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1133853013331	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1133853013332	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1133853013333	Probable transposase; Region: OrfB_IS605; pfam01385
1133853013334	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1133853013335	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1133853013336	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
1133853013337	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1133853013338	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1133853013339	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1133853013340	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1133853013341	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1133853013342	dimer interface [polypeptide binding]; other site
1133853013343	ssDNA binding site [nucleotide binding]; other site
1133853013344	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133853013345	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1133853013346	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853013347	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
1133853013348	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1133853013349	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133853013350	intersubunit interface [polypeptide binding]; other site
1133853013351	active site
1133853013352	Zn2+ binding site [ion binding]; other site
1133853013353	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1133853013354	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1133853013355	AP (apurinic/apyrimidinic) site pocket; other site
1133853013356	DNA interaction; other site
1133853013357	Metal-binding active site; metal-binding site
1133853013358	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1133853013359	active site
1133853013360	dimer interface [polypeptide binding]; other site
1133853013361	magnesium binding site [ion binding]; other site
1133853013362	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853013363	active site
1133853013364	phosphorylation site [posttranslational modification]
1133853013365	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1133853013366	active site
1133853013367	P-loop; other site
1133853013368	phosphorylation site [posttranslational modification]
1133853013369	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1133853013370	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1133853013371	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1133853013372	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1133853013373	transcriptional repressor UlaR; Provisional; Region: PRK13509
1133853013374	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853013375	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853013376	esterase; Provisional; Region: PRK10566
1133853013377	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1133853013378	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1133853013379	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1133853013380	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133853013381	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1133853013382	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1133853013383	FAD binding site [chemical binding]; other site
1133853013384	substrate binding site [chemical binding]; other site
1133853013385	catalytic residues [active]
1133853013386	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1133853013387	Predicted integral membrane protein [Function unknown]; Region: COG5463
1133853013388	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1133853013389	Predicted membrane protein [Function unknown]; Region: COG3766
1133853013390	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1133853013391	PspA/IM30 family; Region: PspA_IM30; pfam04012
1133853013392	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1133853013393	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1133853013394	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1133853013395	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1133853013396	exoribonuclease R; Provisional; Region: PRK11642
1133853013397	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
1133853013398	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1133853013399	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1133853013400	RNB domain; Region: RNB; pfam00773
1133853013401	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1133853013402	RNA binding site [nucleotide binding]; other site
1133853013403	Predicted transcriptional regulator [Transcription]; Region: COG1959
1133853013404	transcriptional repressor NsrR; Provisional; Region: PRK11014
1133853013405	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1133853013406	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1133853013407	GDP-binding site [chemical binding]; other site
1133853013408	ACT binding site; other site
1133853013409	IMP binding site; other site
1133853013410	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1133853013411	FtsH protease regulator HflC; Provisional; Region: PRK11029
1133853013412	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1133853013413	FtsH protease regulator HflK; Provisional; Region: PRK10930
1133853013414	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1133853013415	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1133853013416	GTPase HflX; Provisional; Region: PRK11058
1133853013417	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1133853013418	HflX GTPase family; Region: HflX; cd01878
1133853013419	G1 box; other site
1133853013420	GTP/Mg2+ binding site [chemical binding]; other site
1133853013421	Switch I region; other site
1133853013422	G2 box; other site
1133853013423	G3 box; other site
1133853013424	Switch II region; other site
1133853013425	G4 box; other site
1133853013426	G5 box; other site
1133853013427	bacterial Hfq-like; Region: Hfq; cd01716
1133853013428	hexamer interface [polypeptide binding]; other site
1133853013429	Sm1 motif; other site
1133853013430	RNA binding site [nucleotide binding]; other site
1133853013431	Sm2 motif; other site
1133853013432	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1133853013433	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1133853013434	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1133853013435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853013436	ATP binding site [chemical binding]; other site
1133853013437	Mg2+ binding site [ion binding]; other site
1133853013438	G-X-G motif; other site
1133853013439	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1133853013440	ATP binding site [chemical binding]; other site
1133853013441	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1133853013442	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1133853013443	AMIN domain; Region: AMIN; pfam11741
1133853013444	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1133853013445	active site
1133853013446	metal binding site [ion binding]; metal-binding site
1133853013447	ADP-binding protein; Provisional; Region: PRK10646
1133853013448	putative carbohydrate kinase; Provisional; Region: PRK10565
1133853013449	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
1133853013450	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1133853013451	putative substrate binding site [chemical binding]; other site
1133853013452	putative ATP binding site [chemical binding]; other site
1133853013453	epoxyqueuosine reductase; Region: TIGR00276
1133853013454	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1133853013455	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1133853013456	catalytic site [active]
1133853013457	putative active site [active]
1133853013458	putative substrate binding site [chemical binding]; other site
1133853013459	dimer interface [polypeptide binding]; other site
1133853013460	GTPase RsgA; Reviewed; Region: PRK12288
1133853013461	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1133853013462	RNA binding site [nucleotide binding]; other site
1133853013463	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1133853013464	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1133853013465	GTP/Mg2+ binding site [chemical binding]; other site
1133853013466	G4 box; other site
1133853013467	G5 box; other site
1133853013468	G1 box; other site
1133853013469	Switch I region; other site
1133853013470	G2 box; other site
1133853013471	G3 box; other site
1133853013472	Switch II region; other site
1133853013473	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1133853013474	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1133853013475	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
1133853013476	DNA-binding site [nucleotide binding]; DNA binding site
1133853013477	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1133853013478	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133853013479	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1133853013480	inner membrane transporter YjeM; Provisional; Region: PRK15238
1133853013481	poxB regulator PoxA; Provisional; Region: PRK09350
1133853013482	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1133853013483	motif 1; other site
1133853013484	dimer interface [polypeptide binding]; other site
1133853013485	active site
1133853013486	motif 2; other site
1133853013487	motif 3; other site
1133853013488	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1133853013489	L-aspartate oxidase; Provisional; Region: PRK06175
1133853013490	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1133853013491	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1133853013492	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1133853013493	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1133853013494	D-subunit interface [polypeptide binding]; other site
1133853013495	Iron-sulfur protein interface; other site
1133853013496	proximal quinone binding site [chemical binding]; other site
1133853013497	distal quinone binding site [chemical binding]; other site
1133853013498	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1133853013499	Iron-sulfur protein interface; other site
1133853013500	proximal quinone binding site [chemical binding]; other site
1133853013501	C-subunit interface; other site
1133853013502	distal quinone binding site; other site
1133853013503	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1133853013504	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1133853013505	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
1133853013506	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1133853013507	multidrug efflux system protein; Provisional; Region: PRK11431
1133853013508	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1133853013509	entericidin A; Provisional; Region: PRK09810
1133853013510	elongation factor P; Validated; Region: PRK00529
1133853013511	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1133853013512	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1133853013513	RNA binding site [nucleotide binding]; other site
1133853013514	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1133853013515	RNA binding site [nucleotide binding]; other site
1133853013516	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1133853013517	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853013518	FeS/SAM binding site; other site
1133853013519	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1133853013520	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1133853013521	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1133853013522	ring oligomerisation interface [polypeptide binding]; other site
1133853013523	ATP/Mg binding site [chemical binding]; other site
1133853013524	stacking interactions; other site
1133853013525	hinge regions; other site
1133853013526	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1133853013527	oligomerisation interface [polypeptide binding]; other site
1133853013528	mobile loop; other site
1133853013529	roof hairpin; other site
1133853013530	putative transporter; Provisional; Region: PRK11021
1133853013531	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1133853013532	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1133853013533	Aspartase; Region: Aspartase; cd01357
1133853013534	active sites [active]
1133853013535	tetramer interface [polypeptide binding]; other site
1133853013536	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1133853013537	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1133853013538	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1133853013539	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1133853013540	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1133853013541	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1133853013542	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1133853013543	DsbD alpha interface [polypeptide binding]; other site
1133853013544	catalytic residues [active]
1133853013545	putative transcriptional regulator; Provisional; Region: PRK11640
1133853013546	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853013547	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1133853013548	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133853013549	active site
1133853013550	Int/Topo IB signature motif; other site
1133853013551	potential frameshift: common BLAST hit: gi|218697881|ref|YP_002405548.1| superfamily I DNA helicase
1133853013552	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853013553	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853013554	similar to transposase fragment; COG3436 Transposase and inactivated derivatives
1133853013555	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1133853013556	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133853013557	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133853013558	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133853013559	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853013560	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853013561	potential frameshift: common BLAST hit: gi|116006811|ref|YP_787994.1| putative transposase
1133853013562	potential frameshift: common BLAST hit: gi|218696578|ref|YP_002404245.1| transposase ORF1, IS66 family
1133853013563	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853013564	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853013565	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853013566	Transposase; Region: HTH_Tnp_1; pfam01527
1133853013567	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853013568	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853013569	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133853013570	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133853013571	similar to transposase (fragment); COG3436 Transposase and inactivated derivatives
1133853013572	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853013573	Transposase; Region: HTH_Tnp_1; pfam01527
1133853013574	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853013575	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853013576	Transposase; Region: HTH_Tnp_1; cl17663
1133853013577	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853013578	similar to transposase ORF B (fragment), IS629; COG2801 Transposase and inactivated derivatives
1133853013579	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133853013580	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133853013581	putative active site [active]
1133853013582	putative NTP binding site [chemical binding]; other site
1133853013583	putative nucleic acid binding site [nucleotide binding]; other site
1133853013584	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133853013585	similar to invasion plasmid antigen, fragment; COG2801 Transposase and inactivated derivatives
1133853013586	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1133853013587	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853013588	N-terminal plug; other site
1133853013589	ligand-binding site [chemical binding]; other site
1133853013590	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1133853013591	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1133853013592	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1133853013593	IucA / IucC family; Region: IucA_IucC; pfam04183
1133853013594	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1133853013595	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1133853013596	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
1133853013597	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1133853013598	IucA / IucC family; Region: IucA_IucC; pfam04183
1133853013599	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1133853013600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853013601	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133853013602	putative substrate translocation pore; other site
1133853013603	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853013604	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853013605	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853013606	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853013607	Integrase core domain; Region: rve; pfam00665
1133853013608	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853013609	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853013610	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853013611	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853013612	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853013613	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1133853013614	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1133853013615	DNA-binding interface [nucleotide binding]; DNA binding site
1133853013616	Integrase core domain; Region: rve; pfam00665
1133853013617	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853013618	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853013619	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1133853013620	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133853013621	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133853013622	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133853013623	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133853013624	Integrase core domain; Region: rve; pfam00665
1133853013625	Integrase core domain; Region: rve_3; cl15866
1133853013626	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133853013627	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133853013628	putative active site [active]
1133853013629	putative NTP binding site [chemical binding]; other site
1133853013630	putative nucleic acid binding site [nucleotide binding]; other site
1133853013631	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133853013632	similar to transposase ORF B (fragment), IS629; COG2801 Transposase and inactivated derivatives
1133853013633	Transposase; Region: HTH_Tnp_1; cl17663
1133853013634	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853013635	Antirestriction protein; Region: Antirestrict; pfam03230
1133853013636	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133853013637	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133853013638	MPN+ (JAMM) motif; other site
1133853013639	Zinc-binding site [ion binding]; other site
1133853013640	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133853013641	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133853013642	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133853013643	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133853013644	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133853013645	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1133853013646	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853013647	DNA binding site [nucleotide binding]
1133853013648	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1133853013649	lysine decarboxylase CadA; Provisional; Region: PRK15400
1133853013650	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133853013651	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133853013652	homodimer interface [polypeptide binding]; other site
1133853013653	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853013654	catalytic residue [active]
1133853013655	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133853013656	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133853013657	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853013658	putative substrate translocation pore; other site
1133853013659	POT family; Region: PTR2; pfam00854
1133853013660	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1133853013661	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1133853013662	dimer interface [polypeptide binding]; other site
1133853013663	putative anticodon binding site; other site
1133853013664	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1133853013665	motif 1; other site
1133853013666	active site
1133853013667	motif 2; other site
1133853013668	motif 3; other site
1133853013669	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1133853013670	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1133853013671	Predicted acetyltransferase [General function prediction only]; Region: COG2388
1133853013672	Uncharacterized conserved protein [Function unknown]; Region: COG3592
1133853013673	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1133853013674	PAS domain; Region: PAS; smart00091
1133853013675	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853013676	ATP binding site [chemical binding]; other site
1133853013677	Mg2+ binding site [ion binding]; other site
1133853013678	G-X-G motif; other site
1133853013679	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1133853013680	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853013681	active site
1133853013682	phosphorylation site [posttranslational modification]
1133853013683	intermolecular recognition site; other site
1133853013684	dimerization interface [polypeptide binding]; other site
1133853013685	Transcriptional regulator; Region: CitT; pfam12431
1133853013686	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1133853013687	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1133853013688	fumarate hydratase; Provisional; Region: PRK15389
1133853013689	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1133853013690	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1133853013691	hypothetical protein; Provisional; Region: PRK09867
1133853013692	melibiose:sodium symporter; Provisional; Region: PRK10429
1133853013693	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1133853013694	alpha-galactosidase; Provisional; Region: PRK15076
1133853013695	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1133853013696	NAD binding site [chemical binding]; other site
1133853013697	sugar binding site [chemical binding]; other site
1133853013698	divalent metal binding site [ion binding]; other site
1133853013699	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133853013700	dimer interface [polypeptide binding]; other site
1133853013701	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1133853013702	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853013703	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853013704	arginine decarboxylase; Provisional; Region: PRK15029
1133853013705	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133853013706	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133853013707	homodimer interface [polypeptide binding]; other site
1133853013708	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853013709	catalytic residue [active]
1133853013710	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133853013711	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853013712	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853013713	arginine:agmatin antiporter; Provisional; Region: PRK10644
1133853013714	putative metal dependent hydrolase; Provisional; Region: PRK11598
1133853013715	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1133853013716	Sulfatase; Region: Sulfatase; pfam00884
1133853013717	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1133853013718	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853013719	active site
1133853013720	phosphorylation site [posttranslational modification]
1133853013721	intermolecular recognition site; other site
1133853013722	dimerization interface [polypeptide binding]; other site
1133853013723	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853013724	DNA binding site [nucleotide binding]
1133853013725	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1133853013726	HAMP domain; Region: HAMP; pfam00672
1133853013727	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853013728	dimer interface [polypeptide binding]; other site
1133853013729	phosphorylation site [posttranslational modification]
1133853013730	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853013731	ATP binding site [chemical binding]; other site
1133853013732	Mg2+ binding site [ion binding]; other site
1133853013733	G-X-G motif; other site
1133853013734	proline/glycine betaine transporter; Provisional; Region: PRK10642
1133853013735	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853013736	putative substrate translocation pore; other site
1133853013737	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1133853013738	YjcZ-like protein; Region: YjcZ; pfam13990
1133853013739	hypothetical protein; Provisional; Region: PRK09866
1133853013740	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133853013741	G1 box; other site
1133853013742	GTP/Mg2+ binding site [chemical binding]; other site
1133853013743	G2 box; other site
1133853013744	Switch I region; other site
1133853013745	G3 box; other site
1133853013746	Switch II region; other site
1133853013747	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1133853013748	G2 box; other site
1133853013749	Switch I region; other site
1133853013750	G3 box; other site
1133853013751	Switch II region; other site
1133853013752	G4 box; other site
1133853013753	G5 box; other site
1133853013754	hypothetical protein; Provisional; Region: PRK10220
1133853013755	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1133853013756	PhnA protein; Region: PhnA; pfam03831
1133853013757	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1133853013758	dimer interface [polypeptide binding]; other site
1133853013759	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1133853013760	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
1133853013761	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1133853013762	Walker A/P-loop; other site
1133853013763	ATP binding site [chemical binding]; other site
1133853013764	Q-loop/lid; other site
1133853013765	ABC transporter signature motif; other site
1133853013766	Walker B; other site
1133853013767	D-loop; other site
1133853013768	H-loop/switch region; other site
1133853013769	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1133853013770	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853013771	substrate binding pocket [chemical binding]; other site
1133853013772	membrane-bound complex binding site; other site
1133853013773	hinge residues; other site
1133853013774	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
1133853013775	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853013776	dimer interface [polypeptide binding]; other site
1133853013777	conserved gate region; other site
1133853013778	putative PBP binding loops; other site
1133853013779	ABC-ATPase subunit interface; other site
1133853013780	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1133853013781	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853013782	DNA-binding site [nucleotide binding]; DNA binding site
1133853013783	UTRA domain; Region: UTRA; pfam07702
1133853013784	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
1133853013785	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
1133853013786	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
1133853013787	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
1133853013788	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1133853013789	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133853013790	Walker A/P-loop; other site
1133853013791	ATP binding site [chemical binding]; other site
1133853013792	Q-loop/lid; other site
1133853013793	ABC transporter signature motif; other site
1133853013794	Walker B; other site
1133853013795	D-loop; other site
1133853013796	H-loop/switch region; other site
1133853013797	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133853013798	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1133853013799	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133853013800	Walker A/P-loop; other site
1133853013801	ATP binding site [chemical binding]; other site
1133853013802	Q-loop/lid; other site
1133853013803	ABC transporter signature motif; other site
1133853013804	Walker B; other site
1133853013805	D-loop; other site
1133853013806	H-loop/switch region; other site
1133853013807	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1133853013808	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1133853013809	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1133853013810	active site
1133853013811	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
1133853013812	AAA domain; Region: AAA_18; pfam13238
1133853013813	active site
1133853013814	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853013815	Coenzyme A binding pocket [chemical binding]; other site
1133853013816	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
1133853013817	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1133853013818	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1133853013819	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1133853013820	multidrug resistance protein MdtN; Provisional; Region: PRK10476
1133853013821	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133853013822	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133853013823	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
1133853013824	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133853013825	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
1133853013826	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853013827	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853013828	molybdopterin cofactor binding site; other site
1133853013829	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1133853013830	molybdopterin cofactor binding site; other site
1133853013831	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133853013832	Sel1-like repeats; Region: SEL1; smart00671
1133853013833	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1133853013834	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1133853013835	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1133853013836	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133853013837	binding surface
1133853013838	TPR motif; other site
1133853013839	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1133853013840	heme lyase subunit NrfE; Provisional; Region: PRK10369
1133853013841	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1133853013842	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1133853013843	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1133853013844	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1133853013845	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1133853013846	acetyl-CoA synthetase; Provisional; Region: PRK00174
1133853013847	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1133853013848	active site
1133853013849	CoA binding site [chemical binding]; other site
1133853013850	acyl-activating enzyme (AAE) consensus motif; other site
1133853013851	AMP binding site [chemical binding]; other site
1133853013852	acetate binding site [chemical binding]; other site
1133853013853	Predicted membrane protein [Function unknown]; Region: COG3162
1133853013854	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1133853013855	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1133853013856	Na binding site [ion binding]; other site
1133853013857	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1133853013858	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1133853013859	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1133853013860	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1133853013861	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133853013862	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1133853013863	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1133853013864	DNA binding residues [nucleotide binding]
1133853013865	dimer interface [polypeptide binding]; other site
1133853013866	[2Fe-2S] cluster binding site [ion binding]; other site
1133853013867	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1133853013868	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853013869	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1133853013870	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133853013871	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133853013872	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1133853013873	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1133853013874	dimer interface [polypeptide binding]; other site
1133853013875	ssDNA binding site [nucleotide binding]; other site
1133853013876	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133853013877	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1133853013878	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1133853013879	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1133853013880	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1133853013881	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1133853013882	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1133853013883	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
1133853013884	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853013885	active site
1133853013886	motif I; other site
1133853013887	motif II; other site
1133853013888	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1133853013889	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133853013890	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853013891	homodimer interface [polypeptide binding]; other site
1133853013892	catalytic residue [active]
1133853013893	alanine racemase; Reviewed; Region: alr; PRK00053
1133853013894	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1133853013895	active site
1133853013896	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133853013897	substrate binding site [chemical binding]; other site
1133853013898	catalytic residues [active]
1133853013899	dimer interface [polypeptide binding]; other site
1133853013900	replicative DNA helicase; Provisional; Region: PRK08006
1133853013901	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1133853013902	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1133853013903	Walker A motif; other site
1133853013904	ATP binding site [chemical binding]; other site
1133853013905	Walker B motif; other site
1133853013906	DNA binding loops [nucleotide binding]
1133853013907	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1133853013908	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1133853013909	NADP binding site [chemical binding]; other site
1133853013910	dimer interface [polypeptide binding]; other site
1133853013911	phage shock protein G; Reviewed; Region: pspG; PRK09459
1133853013912	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1133853013913	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1133853013914	FMN binding site [chemical binding]; other site
1133853013915	active site
1133853013916	catalytic residues [active]
1133853013917	substrate binding site [chemical binding]; other site
1133853013918	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
1133853013919	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1133853013920	metal binding site 2 [ion binding]; metal-binding site
1133853013921	putative DNA binding helix; other site
1133853013922	metal binding site 1 [ion binding]; metal-binding site
1133853013923	dimer interface [polypeptide binding]; other site
1133853013924	structural Zn2+ binding site [ion binding]; other site
1133853013925	hypothetical protein; Provisional; Region: PRK10428
1133853013926	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1133853013927	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1133853013928	LexA repressor; Validated; Region: PRK00215
1133853013929	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1133853013930	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853013931	Catalytic site [active]
1133853013932	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1133853013933	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1133853013934	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1133853013935	putative acyl-acceptor binding pocket; other site
1133853013936	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1133853013937	UbiA prenyltransferase family; Region: UbiA; pfam01040
1133853013938	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1133853013939	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1133853013940	SopA-like central domain; Region: SopA; pfam13981
1133853013941	hypothetical protein; Validated; Region: PRK09718
1133853013942	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1133853013943	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1133853013944	trimer interface; other site
1133853013945	sugar binding site [chemical binding]; other site
1133853013946	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1133853013947	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1133853013948	Walker A/P-loop; other site
1133853013949	ATP binding site [chemical binding]; other site
1133853013950	Q-loop/lid; other site
1133853013951	ABC transporter signature motif; other site
1133853013952	Walker B; other site
1133853013953	D-loop; other site
1133853013954	H-loop/switch region; other site
1133853013955	TOBE domain; Region: TOBE_2; pfam08402
1133853013956	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1133853013957	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1133853013958	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1133853013959	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853013960	dimer interface [polypeptide binding]; other site
1133853013961	conserved gate region; other site
1133853013962	putative PBP binding loops; other site
1133853013963	ABC-ATPase subunit interface; other site
1133853013964	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1133853013965	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853013966	dimer interface [polypeptide binding]; other site
1133853013967	conserved gate region; other site
1133853013968	putative PBP binding loops; other site
1133853013969	ABC-ATPase subunit interface; other site
1133853013970	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1133853013971	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853013972	putative substrate translocation pore; other site
1133853013973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853013974	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1133853013975	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1133853013976	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1133853013977	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1133853013978	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1133853013979	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1133853013980	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1133853013981	active site
1133853013982	dimer interface [polypeptide binding]; other site
1133853013983	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1133853013984	dimer interface [polypeptide binding]; other site
1133853013985	active site
1133853013986	aspartate kinase III; Validated; Region: PRK09084
1133853013987	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
1133853013988	nucleotide binding site [chemical binding]; other site
1133853013989	putative catalytic residues [active]
1133853013990	aspartate binding site [chemical binding]; other site
1133853013991	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
1133853013992	lysine allosteric regulatory site; other site
1133853013993	dimer interface [polypeptide binding]; other site
1133853013994	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1133853013995	dimer interface [polypeptide binding]; other site
1133853013996	Zeta toxin; Region: Zeta_toxin; pfam06414
1133853013997	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1133853013998	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1133853013999	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1133853014000	hypothetical protein; Provisional; Region: PRK10515
1133853014001	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1133853014002	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133853014003	RNA binding surface [nucleotide binding]; other site
1133853014004	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1133853014005	probable active site [active]
1133853014006	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1133853014007	active site pocket [active]
1133853014008	oxyanion hole [active]
1133853014009	catalytic triad [active]
1133853014010	active site nucleophile [active]
1133853014011	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1133853014012	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1133853014013	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1133853014014	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1133853014015	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1133853014016	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1133853014017	substrate binding pocket [chemical binding]; other site
1133853014018	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1133853014019	B12 binding site [chemical binding]; other site
1133853014020	cobalt ligand [ion binding]; other site
1133853014021	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1133853014022	transcriptional repressor IclR; Provisional; Region: PRK11569
1133853014023	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133853014024	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133853014025	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
1133853014026	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1133853014027	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1133853014028	isocitrate lyase; Provisional; Region: PRK15063
1133853014029	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1133853014030	tetramer interface [polypeptide binding]; other site
1133853014031	active site
1133853014032	Mg2+/Mn2+ binding site [ion binding]; other site
1133853014033	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1133853014034	malate synthase A; Region: malate_syn_A; TIGR01344
1133853014035	active site
1133853014036	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1133853014037	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1133853014038	proposed active site lysine [active]
1133853014039	conserved cys residue [active]
1133853014040	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133853014041	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853014042	Coenzyme A binding pocket [chemical binding]; other site
1133853014043	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1133853014044	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1133853014045	purine monophosphate binding site [chemical binding]; other site
1133853014046	dimer interface [polypeptide binding]; other site
1133853014047	putative catalytic residues [active]
1133853014048	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1133853014049	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1133853014050	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1133853014051	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1133853014052	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1133853014053	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1133853014054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853014055	active site
1133853014056	phosphorylation site [posttranslational modification]
1133853014057	intermolecular recognition site; other site
1133853014058	dimerization interface [polypeptide binding]; other site
1133853014059	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853014060	Walker A motif; other site
1133853014061	ATP binding site [chemical binding]; other site
1133853014062	Walker B motif; other site
1133853014063	arginine finger; other site
1133853014064	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133853014065	sensor protein ZraS; Provisional; Region: PRK10364
1133853014066	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853014067	dimer interface [polypeptide binding]; other site
1133853014068	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853014069	ATP binding site [chemical binding]; other site
1133853014070	Mg2+ binding site [ion binding]; other site
1133853014071	G-X-G motif; other site
1133853014072	zinc resistance protein; Provisional; Region: zraP; PRK11546
1133853014073	dimer interface [polypeptide binding]; other site
1133853014074	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1133853014075	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1133853014076	IHF dimer interface [polypeptide binding]; other site
1133853014077	IHF - DNA interface [nucleotide binding]; other site
1133853014078	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1133853014079	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1133853014080	Active_site [active]
1133853014081	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1133853014082	substrate binding site [chemical binding]; other site
1133853014083	active site
1133853014084	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1133853014085	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1133853014086	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1133853014087	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1133853014088	putative NADH binding site [chemical binding]; other site
1133853014089	putative active site [active]
1133853014090	nudix motif; other site
1133853014091	putative metal binding site [ion binding]; other site
1133853014092	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1133853014093	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1133853014094	ThiC-associated domain; Region: ThiC-associated; pfam13667
1133853014095	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1133853014096	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1133853014097	thiamine phosphate binding site [chemical binding]; other site
1133853014098	active site
1133853014099	pyrophosphate binding site [ion binding]; other site
1133853014100	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1133853014101	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1133853014102	ATP binding site [chemical binding]; other site
1133853014103	substrate interface [chemical binding]; other site
1133853014104	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1133853014105	thiS-thiF/thiG interaction site; other site
1133853014106	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1133853014107	ThiS interaction site; other site
1133853014108	putative active site [active]
1133853014109	tetramer interface [polypeptide binding]; other site
1133853014110	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1133853014111	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853014112	FeS/SAM binding site; other site
1133853014113	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1133853014114	stationary phase growth adaptation protein; Provisional; Region: PRK09717
1133853014115	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1133853014116	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1133853014117	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1133853014118	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1133853014119	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1133853014120	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1133853014121	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1133853014122	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1133853014123	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1133853014124	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1133853014125	DNA binding site [nucleotide binding]
1133853014126	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1133853014127	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1133853014128	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1133853014129	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1133853014130	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1133853014131	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1133853014132	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1133853014133	RPB3 interaction site [polypeptide binding]; other site
1133853014134	RPB1 interaction site [polypeptide binding]; other site
1133853014135	RPB11 interaction site [polypeptide binding]; other site
1133853014136	RPB10 interaction site [polypeptide binding]; other site
1133853014137	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1133853014138	core dimer interface [polypeptide binding]; other site
1133853014139	peripheral dimer interface [polypeptide binding]; other site
1133853014140	L10 interface [polypeptide binding]; other site
1133853014141	L11 interface [polypeptide binding]; other site
1133853014142	putative EF-Tu interaction site [polypeptide binding]; other site
1133853014143	putative EF-G interaction site [polypeptide binding]; other site
1133853014144	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1133853014145	23S rRNA interface [nucleotide binding]; other site
1133853014146	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1133853014147	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1133853014148	mRNA/rRNA interface [nucleotide binding]; other site
1133853014149	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1133853014150	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1133853014151	23S rRNA interface [nucleotide binding]; other site
1133853014152	L7/L12 interface [polypeptide binding]; other site
1133853014153	putative thiostrepton binding site; other site
1133853014154	L25 interface [polypeptide binding]; other site
1133853014155	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1133853014156	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1133853014157	putative homodimer interface [polypeptide binding]; other site
1133853014158	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1133853014159	heterodimer interface [polypeptide binding]; other site
1133853014160	homodimer interface [polypeptide binding]; other site
1133853014161	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1133853014162	elongation factor Tu; Reviewed; Region: PRK00049
1133853014163	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1133853014164	G1 box; other site
1133853014165	GEF interaction site [polypeptide binding]; other site
1133853014166	GTP/Mg2+ binding site [chemical binding]; other site
1133853014167	Switch I region; other site
1133853014168	G2 box; other site
1133853014169	G3 box; other site
1133853014170	Switch II region; other site
1133853014171	G4 box; other site
1133853014172	G5 box; other site
1133853014173	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1133853014174	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1133853014175	Antibiotic Binding Site [chemical binding]; other site
1133853014176	potential protein location (hypothetical protein O3O_01380 [Escherichia coli O104:H4 str. 2009EL-2071]) that overlaps RNA (tRNA-T)
1133853014177	pantothenate kinase; Provisional; Region: PRK05439
1133853014178	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1133853014179	ATP-binding site [chemical binding]; other site
1133853014180	CoA-binding site [chemical binding]; other site
1133853014181	Mg2+-binding site [ion binding]; other site
1133853014182	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1133853014183	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1133853014184	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1133853014185	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1133853014186	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1133853014187	FAD binding domain; Region: FAD_binding_4; pfam01565
1133853014188	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1133853014189	glutamate racemase; Provisional; Region: PRK00865
1133853014190	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1133853014191	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133853014192	N-terminal plug; other site
1133853014193	ligand-binding site [chemical binding]; other site
1133853014194	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1133853014195	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853014196	S-adenosylmethionine binding site [chemical binding]; other site
1133853014197	hypothetical protein; Provisional; Region: PRK11056
1133853014198	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1133853014199	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133853014200	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1133853014201	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133853014202	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1133853014203	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1133853014204	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853014205	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1133853014206	dimerization interface [polypeptide binding]; other site
1133853014207	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014208	D-galactonate transporter; Region: 2A0114; TIGR00893
1133853014209	putative substrate translocation pore; other site
1133853014210	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1133853014211	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1133853014212	putative active site pocket [active]
1133853014213	putative metal binding site [ion binding]; other site
1133853014214	argininosuccinate lyase; Provisional; Region: PRK04833
1133853014215	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1133853014216	active sites [active]
1133853014217	tetramer interface [polypeptide binding]; other site
1133853014218	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1133853014219	nucleotide binding site [chemical binding]; other site
1133853014220	N-acetyl-L-glutamate binding site [chemical binding]; other site
1133853014221	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1133853014222	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1133853014223	acetylornithine deacetylase; Provisional; Region: PRK05111
1133853014224	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1133853014225	metal binding site [ion binding]; metal-binding site
1133853014226	putative dimer interface [polypeptide binding]; other site
1133853014227	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1133853014228	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1133853014229	hypothetical protein; Provisional; Region: PRK10649
1133853014230	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1133853014231	Sulfatase; Region: Sulfatase; pfam00884
1133853014232	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853014233	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853014234	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133853014235	active site
1133853014236	P-loop; other site
1133853014237	phosphorylation site [posttranslational modification]
1133853014238	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1133853014239	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1133853014240	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1133853014241	dimer interface [polypeptide binding]; other site
1133853014242	active site
1133853014243	glycine loop; other site
1133853014244	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133853014245	active site
1133853014246	P-loop; other site
1133853014247	phosphorylation site [posttranslational modification]
1133853014248	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1133853014249	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1133853014250	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133853014251	dimerization domain swap beta strand [polypeptide binding]; other site
1133853014252	regulatory protein interface [polypeptide binding]; other site
1133853014253	active site
1133853014254	regulatory phosphorylation site [posttranslational modification]; other site
1133853014255	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1133853014256	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1133853014257	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133853014258	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133853014259	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853014260	active site
1133853014261	phosphorylation site [posttranslational modification]
1133853014262	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1133853014263	active site
1133853014264	intersubunit interactions; other site
1133853014265	catalytic residue [active]
1133853014266	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1133853014267	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1133853014268	dimer interface [polypeptide binding]; other site
1133853014269	active site
1133853014270	metal binding site [ion binding]; metal-binding site
1133853014271	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853014272	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1133853014273	EamA-like transporter family; Region: EamA; pfam00892
1133853014274	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1133853014275	EamA-like transporter family; Region: EamA; pfam00892
1133853014276	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1133853014277	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1133853014278	heme binding site [chemical binding]; other site
1133853014279	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1133853014280	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1133853014281	FAD binding site [chemical binding]; other site
1133853014282	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1133853014283	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1133853014284	putative catalytic residues [active]
1133853014285	putative nucleotide binding site [chemical binding]; other site
1133853014286	putative aspartate binding site [chemical binding]; other site
1133853014287	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1133853014288	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1133853014289	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1133853014290	cystathionine gamma-synthase; Provisional; Region: PRK08045
1133853014291	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1133853014292	homodimer interface [polypeptide binding]; other site
1133853014293	substrate-cofactor binding pocket; other site
1133853014294	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853014295	catalytic residue [active]
1133853014296	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1133853014297	dimerization interface [polypeptide binding]; other site
1133853014298	DNA binding site [nucleotide binding]
1133853014299	corepressor binding sites; other site
1133853014300	potential frameshift: common BLAST hit: gi|254795943|ref|YP_003080780.1| peptidoglycan peptidase
1133853014301	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853014302	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853014303	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853014304	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853014305	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853014306	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853014307	RHS protein; Region: RHS; pfam03527
1133853014308	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133853014309	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1133853014310	PAAR motif; Region: PAAR_motif; cl15808
1133853014311	RHS Repeat; Region: RHS_repeat; pfam05593
1133853014312	RHS Repeat; Region: RHS_repeat; pfam05593
1133853014313	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133853014314	RHS Repeat; Region: RHS_repeat; pfam05593
1133853014315	RHS Repeat; Region: RHS_repeat; pfam05593
1133853014316	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1133853014317	primosome assembly protein PriA; Validated; Region: PRK05580
1133853014318	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853014319	ATP binding site [chemical binding]; other site
1133853014320	putative Mg++ binding site [ion binding]; other site
1133853014321	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1133853014322	ATP-binding site [chemical binding]; other site
1133853014323	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853014324	DNA binding site [nucleotide binding]
1133853014325	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1133853014326	domain linker motif; other site
1133853014327	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1133853014328	dimerization interface [polypeptide binding]; other site
1133853014329	ligand binding site [chemical binding]; other site
1133853014330	essential cell division protein FtsN; Provisional; Region: PRK10927
1133853014331	cell division protein FtsN; Provisional; Region: PRK12757
1133853014332	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1133853014333	active site
1133853014334	HslU subunit interaction site [polypeptide binding]; other site
1133853014335	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1133853014336	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853014337	Walker A motif; other site
1133853014338	ATP binding site [chemical binding]; other site
1133853014339	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1133853014340	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133853014341	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1133853014342	UbiA prenyltransferase family; Region: UbiA; pfam01040
1133853014343	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1133853014344	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1133853014345	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1133853014346	amphipathic channel; other site
1133853014347	Asn-Pro-Ala signature motifs; other site
1133853014348	glycerol kinase; Provisional; Region: glpK; PRK00047
1133853014349	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1133853014350	N- and C-terminal domain interface [polypeptide binding]; other site
1133853014351	active site
1133853014352	MgATP binding site [chemical binding]; other site
1133853014353	catalytic site [active]
1133853014354	metal binding site [ion binding]; metal-binding site
1133853014355	glycerol binding site [chemical binding]; other site
1133853014356	homotetramer interface [polypeptide binding]; other site
1133853014357	homodimer interface [polypeptide binding]; other site
1133853014358	FBP binding site [chemical binding]; other site
1133853014359	protein IIAGlc interface [polypeptide binding]; other site
1133853014360	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1133853014361	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1133853014362	putative active site [active]
1133853014363	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1133853014364	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1133853014365	FAD binding pocket [chemical binding]; other site
1133853014366	FAD binding motif [chemical binding]; other site
1133853014367	phosphate binding motif [ion binding]; other site
1133853014368	beta-alpha-beta structure motif; other site
1133853014369	NAD binding pocket [chemical binding]; other site
1133853014370	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133853014371	Ligand Binding Site [chemical binding]; other site
1133853014372	hypothetical protein; Provisional; Region: PRK09981
1133853014373	Predicted membrane protein [Function unknown]; Region: COG3152
1133853014374	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1133853014375	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1133853014376	triosephosphate isomerase; Provisional; Region: PRK14567
1133853014377	substrate binding site [chemical binding]; other site
1133853014378	dimer interface [polypeptide binding]; other site
1133853014379	catalytic triad [active]
1133853014380	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1133853014381	sulfate transporter subunit; Provisional; Region: PRK10752
1133853014382	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1133853014383	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1133853014384	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1133853014385	active site
1133853014386	ADP/pyrophosphate binding site [chemical binding]; other site
1133853014387	dimerization interface [polypeptide binding]; other site
1133853014388	allosteric effector site; other site
1133853014389	fructose-1,6-bisphosphate binding site; other site
1133853014390	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1133853014391	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1133853014392	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1133853014393	dimer interface [polypeptide binding]; other site
1133853014394	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1133853014395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853014396	active site
1133853014397	intermolecular recognition site; other site
1133853014398	dimerization interface [polypeptide binding]; other site
1133853014399	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133853014400	DNA binding site [nucleotide binding]
1133853014401	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1133853014402	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133853014403	dimerization interface [polypeptide binding]; other site
1133853014404	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853014405	dimer interface [polypeptide binding]; other site
1133853014406	phosphorylation site [posttranslational modification]
1133853014407	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853014408	ATP binding site [chemical binding]; other site
1133853014409	Mg2+ binding site [ion binding]; other site
1133853014410	G-X-G motif; other site
1133853014411	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1133853014412	MOSC domain; Region: MOSC; pfam03473
1133853014413	3-alpha domain; Region: 3-alpha; pfam03475
1133853014414	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
1133853014415	superoxide dismutase; Provisional; Region: PRK10925
1133853014416	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1133853014417	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1133853014418	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1133853014419	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1133853014420	transcriptional activator RhaR; Provisional; Region: PRK13500
1133853014421	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133853014422	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853014423	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853014424	transcriptional activator RhaS; Provisional; Region: PRK13503
1133853014425	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133853014426	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853014427	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853014428	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1133853014429	N- and C-terminal domain interface [polypeptide binding]; other site
1133853014430	active site
1133853014431	putative catalytic site [active]
1133853014432	metal binding site [ion binding]; metal-binding site
1133853014433	ATP binding site [chemical binding]; other site
1133853014434	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1133853014435	carbohydrate binding site [chemical binding]; other site
1133853014436	L-rhamnose isomerase; Provisional; Region: PRK01076
1133853014437	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1133853014438	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133853014439	intersubunit interface [polypeptide binding]; other site
1133853014440	active site
1133853014441	Zn2+ binding site [ion binding]; other site
1133853014442	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1133853014443	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853014444	active site
1133853014445	phosphorylation site [posttranslational modification]
1133853014446	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1133853014447	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133853014448	active site
1133853014449	P-loop; other site
1133853014450	phosphorylation site [posttranslational modification]
1133853014451	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1133853014452	putative peptidase; Provisional; Region: PRK09864
1133853014453	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1133853014454	oligomer interface [polypeptide binding]; other site
1133853014455	active site
1133853014456	metal binding site [ion binding]; metal-binding site
1133853014457	putative frv operon regulatory protein; Provisional; Region: PRK09863
1133853014458	HTH domain; Region: HTH_11; pfam08279
1133853014459	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133853014460	active site
1133853014461	phosphorylation site [posttranslational modification]
1133853014462	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1133853014463	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1133853014464	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853014465	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133853014466	molybdopterin cofactor binding site; other site
1133853014467	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1133853014468	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1133853014469	molybdopterin cofactor binding site; other site
1133853014470	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1133853014471	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1133853014472	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1133853014473	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1133853014474	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1133853014475	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1133853014476	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133853014477	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1133853014478	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133853014479	non-specific DNA binding site [nucleotide binding]; other site
1133853014480	salt bridge; other site
1133853014481	sequence-specific DNA binding site [nucleotide binding]; other site
1133853014482	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1133853014483	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1133853014484	substrate binding pocket [chemical binding]; other site
1133853014485	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133853014486	Coenzyme A binding pocket [chemical binding]; other site
1133853014487	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1133853014488	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1133853014489	putative active site [active]
1133853014490	dimerization interface [polypeptide binding]; other site
1133853014491	putative tRNAtyr binding site [nucleotide binding]; other site
1133853014492	hypothetical protein; Reviewed; Region: PRK01637
1133853014493	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1133853014494	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853014495	motif II; other site
1133853014496	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
1133853014497	active site
1133853014498	catalytic residues [active]
1133853014499	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014500	metabolite-proton symporter; Region: 2A0106; TIGR00883
1133853014501	putative substrate translocation pore; other site
1133853014502	benzoate transport; Region: 2A0115; TIGR00895
1133853014503	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014504	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014505	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133853014506	putative oxidoreductase; Provisional; Region: PRK10083
1133853014507	NAD(P) binding site [chemical binding]; other site
1133853014508	Class I aldolases; Region: Aldolase_Class_I; cl17187
1133853014509	catalytic residue [active]
1133853014510	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1133853014511	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1133853014512	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853014513	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1133853014514	substrate binding site [chemical binding]; other site
1133853014515	ATP binding site [chemical binding]; other site
1133853014516	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133853014517	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133853014518	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133853014519	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014520	putative substrate translocation pore; other site
1133853014521	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
1133853014522	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1133853014523	transcriptional regulator protein; Region: phnR; TIGR03337
1133853014524	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853014525	DNA-binding site [nucleotide binding]; DNA binding site
1133853014526	UTRA domain; Region: UTRA; pfam07702
1133853014527	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1133853014528	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1133853014529	G1 box; other site
1133853014530	putative GEF interaction site [polypeptide binding]; other site
1133853014531	GTP/Mg2+ binding site [chemical binding]; other site
1133853014532	Switch I region; other site
1133853014533	G2 box; other site
1133853014534	G3 box; other site
1133853014535	Switch II region; other site
1133853014536	G4 box; other site
1133853014537	G5 box; other site
1133853014538	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1133853014539	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1133853014540	glutamine synthetase; Provisional; Region: glnA; PRK09469
1133853014541	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1133853014542	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1133853014543	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1133853014544	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133853014545	putative active site [active]
1133853014546	heme pocket [chemical binding]; other site
1133853014547	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133853014548	dimer interface [polypeptide binding]; other site
1133853014549	phosphorylation site [posttranslational modification]
1133853014550	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133853014551	ATP binding site [chemical binding]; other site
1133853014552	Mg2+ binding site [ion binding]; other site
1133853014553	G-X-G motif; other site
1133853014554	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1133853014555	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133853014556	active site
1133853014557	phosphorylation site [posttranslational modification]
1133853014558	intermolecular recognition site; other site
1133853014559	dimerization interface [polypeptide binding]; other site
1133853014560	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853014561	Walker A motif; other site
1133853014562	ATP binding site [chemical binding]; other site
1133853014563	Walker B motif; other site
1133853014564	arginine finger; other site
1133853014565	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133853014566	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1133853014567	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853014568	FeS/SAM binding site; other site
1133853014569	HemN C-terminal domain; Region: HemN_C; pfam06969
1133853014570	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1133853014571	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1133853014572	G1 box; other site
1133853014573	GTP/Mg2+ binding site [chemical binding]; other site
1133853014574	Switch I region; other site
1133853014575	G2 box; other site
1133853014576	G3 box; other site
1133853014577	Switch II region; other site
1133853014578	G4 box; other site
1133853014579	G5 box; other site
1133853014580	DNA polymerase I; Provisional; Region: PRK05755
1133853014581	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1133853014582	active site
1133853014583	metal binding site 1 [ion binding]; metal-binding site
1133853014584	putative 5' ssDNA interaction site; other site
1133853014585	metal binding site 3; metal-binding site
1133853014586	metal binding site 2 [ion binding]; metal-binding site
1133853014587	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1133853014588	putative DNA binding site [nucleotide binding]; other site
1133853014589	putative metal binding site [ion binding]; other site
1133853014590	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1133853014591	active site
1133853014592	catalytic site [active]
1133853014593	substrate binding site [chemical binding]; other site
1133853014594	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1133853014595	active site
1133853014596	DNA binding site [nucleotide binding]
1133853014597	catalytic site [active]
1133853014598	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1133853014599	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1133853014600	putative acyl-acceptor binding pocket; other site
1133853014601	hypothetical protein; Provisional; Region: PRK11367
1133853014602	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1133853014603	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1133853014604	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1133853014605	catalytic residues [active]
1133853014606	hinge region; other site
1133853014607	alpha helical domain; other site
1133853014608	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1133853014609	serine/threonine protein kinase; Provisional; Region: PRK11768
1133853014610	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1133853014611	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1133853014612	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1133853014613	GTP binding site; other site
1133853014614	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1133853014615	Walker A motif; other site
1133853014616	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1133853014617	potassium transporter; Provisional; Region: PRK10750
1133853014618	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1133853014619	hypothetical protein; Provisional; Region: PRK11568
1133853014620	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1133853014621	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1133853014622	proline dipeptidase; Provisional; Region: PRK13607
1133853014623	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1133853014624	active site
1133853014625	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1133853014626	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133853014627	substrate binding site [chemical binding]; other site
1133853014628	oxyanion hole (OAH) forming residues; other site
1133853014629	trimer interface [polypeptide binding]; other site
1133853014630	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1133853014631	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133853014632	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133853014633	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1133853014634	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133853014635	dimer interface [polypeptide binding]; other site
1133853014636	active site
1133853014637	FMN reductase; Validated; Region: fre; PRK08051
1133853014638	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1133853014639	FAD binding pocket [chemical binding]; other site
1133853014640	FAD binding motif [chemical binding]; other site
1133853014641	phosphate binding motif [ion binding]; other site
1133853014642	beta-alpha-beta structure motif; other site
1133853014643	NAD binding pocket [chemical binding]; other site
1133853014644	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1133853014645	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1133853014646	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1133853014647	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1133853014648	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1133853014649	active site
1133853014650	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1133853014651	sec-independent translocase; Provisional; Region: PRK01770
1133853014652	sec-independent translocase; Provisional; Region: tatB; PRK00404
1133853014653	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1133853014654	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
1133853014655	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1133853014656	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1133853014657	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1133853014658	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1133853014659	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1133853014660	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853014661	S-adenosylmethionine binding site [chemical binding]; other site
1133853014662	DNA recombination protein RmuC; Provisional; Region: PRK10361
1133853014663	RmuC family; Region: RmuC; pfam02646
1133853014664	uridine phosphorylase; Provisional; Region: PRK11178
1133853014665	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1133853014666	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1133853014667	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1133853014668	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1133853014669	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1133853014670	THF binding site; other site
1133853014671	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1133853014672	substrate binding site [chemical binding]; other site
1133853014673	THF binding site; other site
1133853014674	zinc-binding site [ion binding]; other site
1133853014675	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1133853014676	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853014677	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1133853014678	putative dimerization interface [polypeptide binding]; other site
1133853014679	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1133853014680	EamA-like transporter family; Region: EamA; pfam00892
1133853014681	putative hydrolase; Provisional; Region: PRK10976
1133853014682	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853014683	active site
1133853014684	motif I; other site
1133853014685	motif II; other site
1133853014686	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853014687	lysophospholipase L2; Provisional; Region: PRK10749
1133853014688	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1133853014689	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1133853014690	threonine efflux system; Provisional; Region: PRK10229
1133853014691	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1133853014692	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133853014693	ATP binding site [chemical binding]; other site
1133853014694	putative Mg++ binding site [ion binding]; other site
1133853014695	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853014696	nucleotide binding region [chemical binding]; other site
1133853014697	ATP-binding site [chemical binding]; other site
1133853014698	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1133853014699	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1133853014700	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1133853014701	dimerization interface [polypeptide binding]; other site
1133853014702	substrate binding site [chemical binding]; other site
1133853014703	active site
1133853014704	calcium binding site [ion binding]; other site
1133853014705	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133853014706	CoenzymeA binding site [chemical binding]; other site
1133853014707	subunit interaction site [polypeptide binding]; other site
1133853014708	PHB binding site; other site
1133853014709	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1133853014710	EamA-like transporter family; Region: EamA; cl17759
1133853014711	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1133853014712	magnesium/nickel/cobalt transporter CorA; Provisional; Region: PRK11085
1133853014713	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
1133853014714	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
1133853014715	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1133853014716	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1133853014717	Cl binding site [ion binding]; other site
1133853014718	oligomer interface [polypeptide binding]; other site
1133853014719	Predicted periplasmic protein [Function unknown]; Region: COG3698
1133853014720	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1133853014721	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1133853014722	Part of AAA domain; Region: AAA_19; pfam13245
1133853014723	Family description; Region: UvrD_C_2; pfam13538
1133853014724	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1133853014725	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853014726	motif II; other site
1133853014727	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1133853014728	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1133853014729	active site
1133853014730	DNA binding site [nucleotide binding]
1133853014731	Int/Topo IB signature motif; other site
1133853014732	hypothetical protein; Provisional; Region: PRK10963
1133853014733	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1133853014734	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1133853014735	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1133853014736	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1133853014737	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
1133853014738	DKNYY family; Region: DKNYY; pfam13644
1133853014739	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1133853014740	putative iron binding site [ion binding]; other site
1133853014741	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1133853014742	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1133853014743	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1133853014744	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1133853014745	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1133853014746	domain interfaces; other site
1133853014747	active site
1133853014748	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1133853014749	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1133853014750	active site
1133853014751	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1133853014752	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1133853014753	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1133853014754	HemY protein N-terminus; Region: HemY_N; pfam07219
1133853014755	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1133853014756	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133853014757	FeS/SAM binding site; other site
1133853014758	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1133853014759	putative transport protein YifK; Provisional; Region: PRK10746
1133853014760	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1133853014761	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1133853014762	putative common antigen polymerase; Provisional; Region: PRK02975
1133853014763	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1133853014764	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1133853014765	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1133853014766	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1133853014767	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1133853014768	inhibitor-cofactor binding pocket; inhibition site
1133853014769	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853014770	catalytic residue [active]
1133853014771	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1133853014772	Coenzyme A binding pocket [chemical binding]; other site
1133853014773	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1133853014774	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1133853014775	substrate binding site; other site
1133853014776	tetramer interface; other site
1133853014777	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1133853014778	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1133853014779	NAD binding site [chemical binding]; other site
1133853014780	substrate binding site [chemical binding]; other site
1133853014781	homodimer interface [polypeptide binding]; other site
1133853014782	active site
1133853014783	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1133853014784	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1133853014785	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1133853014786	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1133853014787	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1133853014788	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1133853014789	active site
1133853014790	homodimer interface [polypeptide binding]; other site
1133853014791	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1133853014792	Chain length determinant protein; Region: Wzz; pfam02706
1133853014793	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1133853014794	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1133853014795	Mg++ binding site [ion binding]; other site
1133853014796	putative catalytic motif [active]
1133853014797	substrate binding site [chemical binding]; other site
1133853014798	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1133853014799	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1133853014800	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1133853014801	RNA binding site [nucleotide binding]; other site
1133853014802	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1133853014803	multimer interface [polypeptide binding]; other site
1133853014804	Walker A motif; other site
1133853014805	ATP binding site [chemical binding]; other site
1133853014806	Walker B motif; other site
1133853014807	putative rho operon leader peptide; Provisional; Region: PRK09979
1133853014808	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1133853014809	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1133853014810	catalytic residues [active]
1133853014811	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1133853014812	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133853014813	ATP binding site [chemical binding]; other site
1133853014814	Mg++ binding site [ion binding]; other site
1133853014815	motif III; other site
1133853014816	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133853014817	nucleotide binding region [chemical binding]; other site
1133853014818	ATP-binding site [chemical binding]; other site
1133853014819	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1133853014820	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1133853014821	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1133853014822	Part of AAA domain; Region: AAA_19; pfam13245
1133853014823	Family description; Region: UvrD_C_2; pfam13538
1133853014824	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
1133853014825	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1133853014826	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1133853014827	ketol-acid reductoisomerase; Validated; Region: PRK05225
1133853014828	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1133853014829	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1133853014830	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1133853014831	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853014832	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1133853014833	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1133853014834	putative dimerization interface [polypeptide binding]; other site
1133853014835	threonine dehydratase; Reviewed; Region: PRK09224
1133853014836	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1133853014837	tetramer interface [polypeptide binding]; other site
1133853014838	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133853014839	catalytic residue [active]
1133853014840	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1133853014841	putative Ile/Val binding site [chemical binding]; other site
1133853014842	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1133853014843	putative Ile/Val binding site [chemical binding]; other site
1133853014844	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1133853014845	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1133853014846	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1133853014847	homodimer interface [polypeptide binding]; other site
1133853014848	substrate-cofactor binding pocket; other site
1133853014849	catalytic residue [active]
1133853014850	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1133853014851	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1133853014852	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133853014853	PYR/PP interface [polypeptide binding]; other site
1133853014854	dimer interface [polypeptide binding]; other site
1133853014855	TPP binding site [chemical binding]; other site
1133853014856	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133853014857	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1133853014858	TPP-binding site [chemical binding]; other site
1133853014859	dimer interface [polypeptide binding]; other site
1133853014860	putative ATP-dependent protease; Provisional; Region: PRK09862
1133853014861	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1133853014862	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853014863	Walker A motif; other site
1133853014864	ATP binding site [chemical binding]; other site
1133853014865	Walker B motif; other site
1133853014866	arginine finger; other site
1133853014867	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1133853014868	hypothetical protein; Provisional; Region: PRK11027
1133853014869	transcriptional regulator HdfR; Provisional; Region: PRK03601
1133853014870	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853014871	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1133853014872	dimerization interface [polypeptide binding]; other site
1133853014873	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1133853014874	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133853014875	DNA-binding site [nucleotide binding]; DNA binding site
1133853014876	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133853014877	putative transporter; Provisional; Region: PRK10504
1133853014878	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014879	putative substrate translocation pore; other site
1133853014880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853014881	transcriptional repressor RbsR; Provisional; Region: PRK10423
1133853014882	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133853014883	DNA binding site [nucleotide binding]
1133853014884	domain linker motif; other site
1133853014885	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1133853014886	dimerization interface [polypeptide binding]; other site
1133853014887	ligand binding site [chemical binding]; other site
1133853014888	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1133853014889	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1133853014890	substrate binding site [chemical binding]; other site
1133853014891	dimer interface [polypeptide binding]; other site
1133853014892	ATP binding site [chemical binding]; other site
1133853014893	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1133853014894	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1133853014895	ligand binding site [chemical binding]; other site
1133853014896	dimerization interface [polypeptide binding]; other site
1133853014897	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1133853014898	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133853014899	TM-ABC transporter signature motif; other site
1133853014900	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1133853014901	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133853014902	Walker A/P-loop; other site
1133853014903	ATP binding site [chemical binding]; other site
1133853014904	Q-loop/lid; other site
1133853014905	ABC transporter signature motif; other site
1133853014906	Walker B; other site
1133853014907	D-loop; other site
1133853014908	H-loop/switch region; other site
1133853014909	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133853014910	D-ribose pyranase; Provisional; Region: PRK11797
1133853014911	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1133853014912	potassium uptake protein; Region: kup; TIGR00794
1133853014913	regulatory ATPase RavA; Provisional; Region: PRK13531
1133853014914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133853014915	Walker A motif; other site
1133853014916	ATP binding site [chemical binding]; other site
1133853014917	Walker B motif; other site
1133853014918	arginine finger; other site
1133853014919	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1133853014920	hypothetical protein; Provisional; Region: yieM; PRK10997
1133853014921	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1133853014922	metal ion-dependent adhesion site (MIDAS); other site
1133853014923	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1133853014924	dimer interface [polypeptide binding]; other site
1133853014925	active site
1133853014926	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1133853014927	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133853014928	putative DNA binding site [nucleotide binding]; other site
1133853014929	putative Zn2+ binding site [ion binding]; other site
1133853014930	AsnC family; Region: AsnC_trans_reg; pfam01037
1133853014931	FMN-binding protein MioC; Provisional; Region: PRK09004
1133853014932	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1133853014933	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1133853014934	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1133853014935	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1133853014936	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133853014937	S-adenosylmethionine binding site [chemical binding]; other site
1133853014938	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1133853014939	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1133853014940	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1133853014941	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1133853014942	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1133853014943	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1133853014944	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1133853014945	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1133853014946	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1133853014947	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1133853014948	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1133853014949	beta subunit interaction interface [polypeptide binding]; other site
1133853014950	Walker A motif; other site
1133853014951	ATP binding site [chemical binding]; other site
1133853014952	Walker B motif; other site
1133853014953	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1133853014954	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1133853014955	core domain interface [polypeptide binding]; other site
1133853014956	delta subunit interface [polypeptide binding]; other site
1133853014957	epsilon subunit interface [polypeptide binding]; other site
1133853014958	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1133853014959	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1133853014960	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1133853014961	alpha subunit interaction interface [polypeptide binding]; other site
1133853014962	Walker A motif; other site
1133853014963	ATP binding site [chemical binding]; other site
1133853014964	Walker B motif; other site
1133853014965	inhibitor binding site; inhibition site
1133853014966	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1133853014967	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1133853014968	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1133853014969	gamma subunit interface [polypeptide binding]; other site
1133853014970	epsilon subunit interface [polypeptide binding]; other site
1133853014971	LBP interface [polypeptide binding]; other site
1133853014972	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1133853014973	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1133853014974	Substrate binding site; other site
1133853014975	Mg++ binding site; other site
1133853014976	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1133853014977	active site
1133853014978	substrate binding site [chemical binding]; other site
1133853014979	CoA binding site [chemical binding]; other site
1133853014980	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1133853014981	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1133853014982	glutaminase active site [active]
1133853014983	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1133853014984	dimer interface [polypeptide binding]; other site
1133853014985	active site
1133853014986	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1133853014987	dimer interface [polypeptide binding]; other site
1133853014988	active site
1133853014989	fimbrial protein; Provisional; Region: lpfA; PRK15289
1133853014990	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
1133853014991	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853014992	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853014993	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133853014994	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853014995	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853014996	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853014997	Fimbrial protein; Region: Fimbrial; cl01416
1133853014998	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133853014999	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1133853015000	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853015001	dimer interface [polypeptide binding]; other site
1133853015002	conserved gate region; other site
1133853015003	putative PBP binding loops; other site
1133853015004	ABC-ATPase subunit interface; other site
1133853015005	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1133853015006	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133853015007	dimer interface [polypeptide binding]; other site
1133853015008	conserved gate region; other site
1133853015009	putative PBP binding loops; other site
1133853015010	ABC-ATPase subunit interface; other site
1133853015011	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1133853015012	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1133853015013	Walker A/P-loop; other site
1133853015014	ATP binding site [chemical binding]; other site
1133853015015	Q-loop/lid; other site
1133853015016	ABC transporter signature motif; other site
1133853015017	Walker B; other site
1133853015018	D-loop; other site
1133853015019	H-loop/switch region; other site
1133853015020	transcriptional regulator PhoU; Provisional; Region: PRK11115
1133853015021	PhoU domain; Region: PhoU; pfam01895
1133853015022	PhoU domain; Region: PhoU; pfam01895
1133853015023	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1133853015024	PRD domain; Region: PRD; pfam00874
1133853015025	PRD domain; Region: PRD; pfam00874
1133853015026	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1133853015027	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133853015028	active site turn [active]
1133853015029	phosphorylation site [posttranslational modification]
1133853015030	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133853015031	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1133853015032	HPr interaction site; other site
1133853015033	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1133853015034	active site
1133853015035	phosphorylation site [posttranslational modification]
1133853015036	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1133853015037	beta-galactosidase; Region: BGL; TIGR03356
1133853015038	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1133853015039	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1133853015040	trimer interface; other site
1133853015041	sugar binding site [chemical binding]; other site
1133853015042	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1133853015043	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1133853015044	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1133853015045	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1133853015046	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1133853015047	active site
1133853015048	trimer interface [polypeptide binding]; other site
1133853015049	allosteric site; other site
1133853015050	active site lid [active]
1133853015051	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
1133853015052	putative inner membrane protein; Provisional; Region: PRK09823
1133853015053	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1133853015054	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133853015055	active site
1133853015056	motif I; other site
1133853015057	motif II; other site
1133853015058	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133853015059	Predicted flavoprotein [General function prediction only]; Region: COG0431
1133853015060	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1133853015061	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1133853015062	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1133853015063	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133853015064	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1133853015065	substrate binding pocket [chemical binding]; other site
1133853015066	dimerization interface [polypeptide binding]; other site
1133853015067	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1133853015068	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133853015069	putative substrate translocation pore; other site
1133853015070	tryptophan permease TnaB; Provisional; Region: PRK09664
1133853015071	aromatic amino acid transport protein; Region: araaP; TIGR00837
1133853015072	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
1133853015073	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1133853015074	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133853015075	catalytic residue [active]
1133853015076	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
1133853015077	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1133853015078	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1133853015079	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1133853015080	G1 box; other site
1133853015081	GTP/Mg2+ binding site [chemical binding]; other site
1133853015082	Switch I region; other site
1133853015083	G2 box; other site
1133853015084	Switch II region; other site
1133853015085	G3 box; other site
1133853015086	G4 box; other site
1133853015087	G5 box; other site
1133853015088	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1133853015089	membrane protein insertase; Provisional; Region: PRK01318
1133853015090	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1133853015091	hypothetical protein; Validated; Region: PRK00041
1133853015092	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1133853015093	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1133853015094	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1133853015095	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1133853015096	P-loop; other site
1133853015097	Magnesium ion binding site [ion binding]; other site
1133853015098	Phage integrase family; Region: Phage_integrase; pfam00589
1133853015099	active site
1133853015100	DNA binding site [nucleotide binding]
1133853015101	Int/Topo IB signature motif; other site
1133853015102	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
1133853015103	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
1133853015104	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1133853015105	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1133853015106	oligomeric interface; other site
1133853015107	putative active site [active]
1133853015108	homodimer interface [polypeptide binding]; other site
1133853015109	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853015110	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1133853015111	active site
1133853015112	catalytic residues [active]
1133853015113	DNA binding site [nucleotide binding]
1133853015114	Int/Topo IB signature motif; other site
1133853015115	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
1133853015116	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1133853015117	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1133853015118	Predicted transcriptional regulator [Transcription]; Region: COG3905
1133853015119	IncFII RepA protein family; Region: IncFII_repA; cl11495
1133853015120	IncFII RepA protein family; Region: IncFII_repA; cl11495
1133853015121	leader peptide RepL; Provisional; Region: PRK13716
1133853015122	replication protein; Provisional; Region: PRK13702
1133853015123	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853015124	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853015125	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853015126	Transposase; Region: HTH_Tnp_1; pfam01527
1133853015127	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853015128	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015129	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853015130	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1133853015131	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853015132	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015133	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853015134	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853015135	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853015136	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853015137	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015138	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853015139	Transposase; Region: HTH_Tnp_1; pfam01527
1133853015140	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853015141	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
1133853015142	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
1133853015143	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
1133853015144	putative RNA binding sites [nucleotide binding]; other site
1133853015145	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
1133853015146	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK14712
1133853015147	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK14712
1133853015148	AAA domain; Region: AAA_30; pfam13604
1133853015149	DNA helicase TraI; Region: TraI; pfam07057
1133853015150	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1133853015151	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853015152	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853015153	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853015154	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133853015155	TraM protein; Region: Tra_M; pfam05261
1133853015156	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1133853015157	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133853015158	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133853015159	catalytic residue [active]
1133853015160	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133853015161	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1133853015162	catalytic residues [active]
1133853015163	potential frameshift: common BLAST hit: gi|116006799|ref|YP_787982.1| protease IgA1
1133853015164	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853015165	Transposase; Region: HTH_Tnp_1; pfam01527
1133853015166	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853015167	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015168	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853015169	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853015170	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015171	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853015172	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853015173	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853015174	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853015175	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853015176	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
1133853015177	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133853015178	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1133853015179	Walker A/P-loop; other site
1133853015180	ATP binding site [chemical binding]; other site
1133853015181	Q-loop/lid; other site
1133853015182	ABC transporter signature motif; other site
1133853015183	Walker B; other site
1133853015184	D-loop; other site
1133853015185	H-loop/switch region; other site
1133853015186	Uncharacterized conserved protein [Function unknown]; Region: COG2433
1133853015187	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133853015188	similar to transposase ORF A (fragment), IS629; COG2963 Transposase and inactivated derivatives
1133853015189	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853015190	Transposase; Region: HTH_Tnp_1; pfam01527
1133853015191	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133853015192	similar to putative transposase (fragment), IS630 family protein; COG3335 Transposase and inactivated derivatives
1133853015193	similar to putative transposase (fragment), IS630 family protein
1133853015194	similar to Serine protease sat precursor (Secreted autotransporter toxin sat) fragment
1133853015195	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853015196	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853015197	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853015198	similar to 14 kDa aggregative adherence fimbriae I protein, Fragment (modular protein); COG1647 Esterase/lipase
1133853015199	similar to invasion plasmid antigen, fragment; COG2801 Transposase and inactivated derivatives
1133853015200	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133853015201	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1133853015202	putative active site [active]
1133853015203	putative NTP binding site [chemical binding]; other site
1133853015204	putative nucleic acid binding site [nucleotide binding]; other site
1133853015205	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133853015206	potential frameshift: common BLAST hit: gi|254162685|ref|YP_003045793.1| putative transposase insL for insertion sequence IS186
1133853015207	COG2801 Transposase and inactivated derivatives
1133853015208	Transposase; Region: HTH_Tnp_1; cl17663
1133853015209	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853015210	similar to putative transposase ORF B (fragment) IS3; COG2801 Transposase and inactivated derivatives
1133853015211	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133853015212	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133853015213	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133853015214	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133853015215	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133853015216	Transposase; Region: HTH_Tnp_1; cl17663
1133853015217	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133853015218	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133853015219	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133853015220	Transposase domain (DUF772); Region: DUF772; pfam05598
1133853015221	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133853015222	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133853015223	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1133853015224	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
1133853015225	substrate binding pocket [chemical binding]; other site
1133853015226	aspartate-rich region 2; other site
1133853015227	substrate-Mg2+ binding site; other site
1133853015228	similar to Putative tail fiber protein (fragment)
1133853015229	Helix-turn-helix domain; Region: HTH_28; pfam13518
1133853015230	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853015231	Transposase; Region: HTH_Tnp_1; cl17663
1133853015232	putative transposase OrfB; Reviewed; Region: PHA02517
1133853015233	Integrase core domain; Region: rve_3; pfam13683
1133853015234	Integrase core domain; Region: rve; pfam00665
1133853015235	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
1133853015236	homodimer interface [polypeptide binding]; other site
1133853015237	putative GKAP docking site [polypeptide binding]; other site
1133853015238	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133853015239	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015240	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1133853015241	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133853015242	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133853015243	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133853015244	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133853015245	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133853015246	Transposase; Region: HTH_Tnp_1; pfam01527
1133853015247	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133853015248	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133853015249	Enterobacteria AfaD invasin protein; Region: AfaD; pfam05775
1133853015250	PapC N-terminal domain; Region: PapC_N; pfam13954
1133853015251	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1133853015252	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1133853015253	PapC C-terminal domain; Region: PapC_C; pfam13953
1133853015254	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133853015255	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1133853015256	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1133853015257	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1133853015258	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133853015259	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133853015260	catalytic residues [active]
1133853015261	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133853015262	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133853015263	Synaptic Site I dimer interface [polypeptide binding]; other site
1133853015264	DNA binding site [nucleotide binding]
1133853015265	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133853015266	Catalytic site [active]
1133853015267	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1133853015268	active site
1133853015269	DNA binding site [nucleotide binding]
1133853015270	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1133853015271	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
1133853015272	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1133853015273	Mg binding site [ion binding]; other site
1133853015274	nucleotide binding site [chemical binding]; other site
1133853015275	putative protofilament interface [polypeptide binding]; other site
1133853015276	Helix-turn-helix domain; Region: HTH_36; pfam13730