-- dump date   	20140619_085441
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1133852000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1133852000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1133852000003	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
1133852000004	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852000005	Walker A motif; other site
1133852000006	ATP binding site [chemical binding]; other site
1133852000007	Walker B motif; other site
1133852000008	arginine finger; other site
1133852000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1133852000010	DnaA box-binding interface [nucleotide binding]; other site
1133852000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1133852000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1133852000013	putative DNA binding surface [nucleotide binding]; other site
1133852000014	dimer interface [polypeptide binding]; other site
1133852000015	beta-clamp/clamp loader binding surface; other site
1133852000016	beta-clamp/translesion DNA polymerase binding surface; other site
1133852000017	recF protein; Region: recf; TIGR00611
1133852000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852000019	Walker A/P-loop; other site
1133852000020	ATP binding site [chemical binding]; other site
1133852000021	Q-loop/lid; other site
1133852000022	ABC transporter signature motif; other site
1133852000023	Walker B; other site
1133852000024	D-loop; other site
1133852000025	H-loop/switch region; other site
1133852000026	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1133852000027	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852000028	ATP binding site [chemical binding]; other site
1133852000029	Mg2+ binding site [ion binding]; other site
1133852000030	G-X-G motif; other site
1133852000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1133852000032	anchoring element; other site
1133852000033	dimer interface [polypeptide binding]; other site
1133852000034	ATP binding site [chemical binding]; other site
1133852000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1133852000036	active site
1133852000037	putative metal-binding site [ion binding]; other site
1133852000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1133852000039	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852000040	hypothetical protein; Provisional; Region: PRK11426
1133852000041	sugar phosphate phosphatase; Provisional; Region: PRK10513
1133852000042	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852000043	active site
1133852000044	motif I; other site
1133852000045	motif II; other site
1133852000046	hypothetical protein; Provisional; Region: PRK10215
1133852000047	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1133852000048	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852000049	DNA-binding site [nucleotide binding]; DNA binding site
1133852000050	FCD domain; Region: FCD; pfam07729
1133852000051	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1133852000052	Entner-Doudoroff aldolase; Region: eda; TIGR01182
1133852000053	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1133852000054	active site
1133852000055	intersubunit interface [polypeptide binding]; other site
1133852000056	catalytic residue [active]
1133852000057	galactonate dehydratase; Provisional; Region: PRK14017
1133852000058	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1133852000059	putative active site pocket [active]
1133852000060	putative metal binding site [ion binding]; other site
1133852000061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000062	D-galactonate transporter; Region: 2A0114; TIGR00893
1133852000063	putative substrate translocation pore; other site
1133852000064	putative oxidoreductase; Provisional; Region: PRK11445
1133852000065	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
1133852000066	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1133852000067	hypothetical protein; Provisional; Region: PRK11616
1133852000068	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1133852000069	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1133852000070	putative dimer interface [polypeptide binding]; other site
1133852000071	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1133852000072	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1133852000073	putative dimer interface [polypeptide binding]; other site
1133852000074	putative transporter; Validated; Region: PRK03818
1133852000075	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1133852000076	TrkA-C domain; Region: TrkA_C; pfam02080
1133852000077	TrkA-C domain; Region: TrkA_C; pfam02080
1133852000078	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1133852000079	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1133852000080	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852000081	DNA-binding site [nucleotide binding]; DNA binding site
1133852000082	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1133852000083	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1133852000084	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1133852000085	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852000086	active site turn [active]
1133852000087	phosphorylation site [posttranslational modification]
1133852000088	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1133852000089	NAD(P) binding site [chemical binding]; other site
1133852000090	LDH/MDH dimer interface [polypeptide binding]; other site
1133852000091	substrate binding site [chemical binding]; other site
1133852000092	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1133852000093	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133852000094	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000095	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852000096	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000097	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
1133852000098	Na binding site [ion binding]; other site
1133852000099	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1133852000100	Sulfatase; Region: Sulfatase; pfam00884
1133852000101	Predicted membrane protein [Function unknown]; Region: COG2149
1133852000102	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1133852000103	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1133852000104	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1133852000105	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000106	putative substrate translocation pore; other site
1133852000107	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1133852000108	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133852000109	PYR/PP interface [polypeptide binding]; other site
1133852000110	dimer interface [polypeptide binding]; other site
1133852000111	TPP binding site [chemical binding]; other site
1133852000112	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133852000113	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1133852000114	TPP-binding site [chemical binding]; other site
1133852000115	dimer interface [polypeptide binding]; other site
1133852000116	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1133852000117	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1133852000118	putative valine binding site [chemical binding]; other site
1133852000119	dimer interface [polypeptide binding]; other site
1133852000120	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1133852000121	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852000122	active site
1133852000123	phosphorylation site [posttranslational modification]
1133852000124	intermolecular recognition site; other site
1133852000125	dimerization interface [polypeptide binding]; other site
1133852000126	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852000127	DNA binding residues [nucleotide binding]
1133852000128	dimerization interface [polypeptide binding]; other site
1133852000129	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1133852000130	MASE1; Region: MASE1; pfam05231
1133852000131	Histidine kinase; Region: HisKA_3; pfam07730
1133852000132	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852000133	ATP binding site [chemical binding]; other site
1133852000134	Mg2+ binding site [ion binding]; other site
1133852000135	G-X-G motif; other site
1133852000136	regulatory protein UhpC; Provisional; Region: PRK11663
1133852000137	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000138	putative substrate translocation pore; other site
1133852000139	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1133852000140	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000141	putative substrate translocation pore; other site
1133852000142	cryptic adenine deaminase; Provisional; Region: PRK10027
1133852000143	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1133852000144	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1133852000145	active site
1133852000146	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133852000147	Sulfate transporter family; Region: Sulfate_transp; cl19250
1133852000148	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1133852000149	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1133852000150	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000151	putative substrate translocation pore; other site
1133852000152	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1133852000153	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1133852000154	EamA-like transporter family; Region: EamA; pfam00892
1133852000155	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1133852000156	EamA-like transporter family; Region: EamA; pfam00892
1133852000157	sugar efflux transporter B; Provisional; Region: PRK15011
1133852000158	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000159	putative substrate translocation pore; other site
1133852000160	Virulence protein RhuM family; Region: Virulence_RhuM; cl19850
1133852000161	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133852000162	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133852000163	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133852000164	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133852000165	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133852000166	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133852000167	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133852000168	MPN+ (JAMM) motif; other site
1133852000169	Zinc-binding site [ion binding]; other site
1133852000170	Antirestriction protein; Region: Antirestrict; pfam03230
1133852000171	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133852000172	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1133852000173	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852000174	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133852000175	hypothetical protein; Provisional; Region: PRK09945
1133852000176	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133852000177	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852000178	Autotransporter beta-domain; Region: Autotransporter; smart00869
1133852000179	Predicted GTPase [General function prediction only]; Region: COG3596
1133852000180	YfjP GTPase; Region: YfjP; cd11383
1133852000181	G1 box; other site
1133852000182	GTP/Mg2+ binding site [chemical binding]; other site
1133852000183	Switch I region; other site
1133852000184	G2 box; other site
1133852000185	Switch II region; other site
1133852000186	G3 box; other site
1133852000187	G4 box; other site
1133852000188	G5 box; other site
1133852000189	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
1133852000190	Chromosome condensation complex Condensin, subunit G [Chromatin structure and dynamics / Cell division and chromosome partitioning]; Region: YCG1; COG5218
1133852000191	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1133852000192	Haemolysin expression modulating protein; Region: HHA; pfam05321
1133852000193	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133852000194	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852000195	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852000196	Integrase core domain; Region: rve; pfam00665
1133852000197	EamA-like transporter family; Region: EamA; pfam00892
1133852000198	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1133852000199	EamA-like transporter family; Region: EamA; pfam00892
1133852000200	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000201	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852000202	putative substrate translocation pore; other site
1133852000203	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1133852000204	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852000205	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1133852000206	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133852000207	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852000208	putative transcriptional regulator MerR; Provisional; Region: PRK13752
1133852000209	Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783
1133852000210	DNA binding residues [nucleotide binding]
1133852000211	dimer interface [polypeptide binding]; other site
1133852000212	mercury binding site [ion binding]; other site
1133852000213	putative mercuric transport protein; Provisional; Region: PRK13751
1133852000214	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133852000215	metal-binding site [ion binding]
1133852000216	putative mercury transport protein MerC; Provisional; Region: PRK13755
1133852000217	putative mercuric reductase; Provisional; Region: PRK13748
1133852000218	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133852000219	metal-binding site [ion binding]
1133852000220	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852000221	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1133852000222	transcriptional regulator MerD; Provisional; Region: PRK13749
1133852000223	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1133852000224	DNA binding residues [nucleotide binding]
1133852000225	putative mercury resistance protein; Provisional; Region: PRK13747
1133852000226	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852000227	Homeodomain-like domain; Region: HTH_23; pfam13384
1133852000228	Integrase core domain; Region: rve; pfam00665
1133852000229	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133852000230	Transposase; Region: HTH_Tnp_1; cl17663
1133852000231	Integrase core domain; Region: rve; pfam00665
1133852000232	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; pfam04655
1133852000233	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
1133852000234	Phosphotransferase enzyme family; Region: APH; pfam01636
1133852000235	active site
1133852000236	ATP binding site [chemical binding]; other site
1133852000237	antibiotic binding site [chemical binding]; other site
1133852000238	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
1133852000239	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1133852000240	substrate binding pocket [chemical binding]; other site
1133852000241	dimer interface [polypeptide binding]; other site
1133852000242	inhibitor binding site; inhibition site
1133852000243	Replication initiator protein A; Region: RPA; cl19398
1133852000244	Hexameric Replicative Helicase RepA.  RepA is encoded by a plasmid, which is found in most Gram negative bacteria. RepA is a 5'-3' DNA helicase which can utilize ATP, GTP and CTP to a lesser extent; Region: repA; cd01125
1133852000245	hexamer interface [polypeptide binding]; other site
1133852000246	NTP binding site [chemical binding]; other site
1133852000247	Walker B motif; other site
1133852000248	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133852000249	Transposase; Region: HTH_Tnp_1; cl17663
1133852000250	Integrase core domain; Region: rve; pfam00665
1133852000251	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1133852000252	Transposase; Region: HTH_Tnp_1; cl17663
1133852000253	Integrase core domain; Region: rve; pfam00665
1133852000254	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1133852000255	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
1133852000256	substrate binding pocket [chemical binding]; other site
1133852000257	dimer interface [polypeptide binding]; other site
1133852000258	inhibitor binding site; inhibition site
1133852000259	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
1133852000260	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1133852000261	folate binding site [chemical binding]; other site
1133852000262	NADP+ binding site [chemical binding]; other site
1133852000263	integrase/recombinase; Provisional; Region: PRK15417
1133852000264	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
1133852000265	Int/Topo IB signature motif; other site
1133852000266	valyl-tRNA synthetase-like protein; Provisional; Region: PTZ00419
1133852000267	Domain of unknown function (DUF3330); Region: DUF3330; pfam11809
1133852000268	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133852000269	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1133852000270	catalytic residues [active]
1133852000271	catalytic nucleophile [active]
1133852000272	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133852000273	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133852000274	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133852000275	Synaptic Site I dimer interface [polypeptide binding]; other site
1133852000276	DNA binding site [nucleotide binding]
1133852000277	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569
1133852000278	DNA-binding interface [nucleotide binding]; DNA binding site
1133852000279	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
1133852000280	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
1133852000281	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852000282	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852000283	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852000284	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852000285	integrase; Provisional; Region: PRK09692
1133852000286	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852000287	active site
1133852000288	Int/Topo IB signature motif; other site
1133852000289	putative transporter; Provisional; Region: PRK11462
1133852000290	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1133852000291	putative alpha-glucosidase; Provisional; Region: PRK10658
1133852000292	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1133852000293	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1133852000294	active site
1133852000295	homotrimer interface [polypeptide binding]; other site
1133852000296	catalytic site [active]
1133852000297	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1133852000298	AsmA family; Region: AsmA; pfam05170
1133852000299	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1133852000300	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133852000301	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1133852000302	Sulfate transporter family; Region: Sulfate_transp; cl19250
1133852000303	Sodium/glutamate symporter; Region: Glt_symporter; cl19414
1133852000304	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1133852000305	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1133852000306	generic binding surface II; other site
1133852000307	ssDNA binding site; other site
1133852000308	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852000309	ATP binding site [chemical binding]; other site
1133852000310	putative Mg++ binding site [ion binding]; other site
1133852000311	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852000312	nucleotide binding region [chemical binding]; other site
1133852000313	ATP-binding site [chemical binding]; other site
1133852000314	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1133852000315	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1133852000316	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1133852000317	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1133852000318	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133852000319	Zn2+ binding site [ion binding]; other site
1133852000320	Mg2+ binding site [ion binding]; other site
1133852000321	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1133852000322	synthetase active site [active]
1133852000323	NTP binding site [chemical binding]; other site
1133852000324	metal binding site [ion binding]; metal-binding site
1133852000325	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1133852000326	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1133852000327	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1133852000328	Guanylate kinase; Region: Guanylate_kin; pfam00625
1133852000329	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1133852000330	catalytic site [active]
1133852000331	G-X2-G-X-G-K; other site
1133852000332	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1133852000333	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1133852000334	nucleotide binding pocket [chemical binding]; other site
1133852000335	K-X-D-G motif; other site
1133852000336	catalytic site [active]
1133852000337	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1133852000338	Predicted membrane protein [Function unknown]; Region: COG2860
1133852000339	UPF0126 domain; Region: UPF0126; pfam03458
1133852000340	UPF0126 domain; Region: UPF0126; pfam03458
1133852000341	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
1133852000342	BRO family, N-terminal domain; Region: Bro-N; pfam02498
1133852000343	hypothetical protein; Provisional; Region: PRK11820
1133852000344	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1133852000345	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1133852000346	ribonuclease PH; Reviewed; Region: rph; PRK00173
1133852000347	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1133852000348	hexamer interface [polypeptide binding]; other site
1133852000349	active site
1133852000350	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852000351	active site
1133852000352	division inhibitor protein; Provisional; Region: slmA; PRK09480
1133852000353	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852000354	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1133852000355	trimer interface [polypeptide binding]; other site
1133852000356	active site
1133852000357	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1133852000358	Flavoprotein; Region: Flavoprotein; cl19190
1133852000359	DNA / pantothenate metabolizm flavoprotein; Region: DFP; pfam04127
1133852000360	hypothetical protein; Reviewed; Region: PRK00024
1133852000361	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133852000362	MPN+ (JAMM) motif; other site
1133852000363	Zinc-binding site [ion binding]; other site
1133852000364	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1133852000365	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1133852000366	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1133852000367	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1133852000368	DNA binding site [nucleotide binding]
1133852000369	catalytic residue [active]
1133852000370	H2TH interface [polypeptide binding]; other site
1133852000371	putative catalytic residues [active]
1133852000372	turnover-facilitating residue; other site
1133852000373	intercalation triad [nucleotide binding]; other site
1133852000374	8OG recognition residue [nucleotide binding]; other site
1133852000375	putative reading head residues; other site
1133852000376	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1133852000377	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1133852000378	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1133852000379	active site
1133852000380	(T/H)XGH motif; other site
1133852000381	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1133852000382	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1133852000383	Glycosyl transferases group 1; Region: Glycos_transf_1; cl19138
1133852000384	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1133852000385	putative active site [active]
1133852000386	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1133852000387	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1133852000388	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1133852000389	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1133852000390	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1133852000391	Ligand binding site; other site
1133852000392	metal-binding site
1133852000393	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1133852000394	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1133852000395	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1133852000396	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1133852000397	Ligand binding site; other site
1133852000398	metal-binding site
1133852000399	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1133852000400	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1133852000401	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1133852000402	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1133852000403	O-antigen ligase RfaL; Provisional; Region: PRK15487
1133852000404	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1133852000405	putative active site [active]
1133852000406	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1133852000407	putative active site [active]
1133852000408	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1133852000409	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1133852000410	NADP binding site [chemical binding]; other site
1133852000411	homopentamer interface [polypeptide binding]; other site
1133852000412	substrate binding site [chemical binding]; other site
1133852000413	active site
1133852000414	hypothetical protein; Provisional; Region: PRK11346
1133852000415	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
1133852000416	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1133852000417	substrate-cofactor binding pocket; other site
1133852000418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852000419	catalytic residue [active]
1133852000420	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1133852000421	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133852000422	NAD(P) binding site [chemical binding]; other site
1133852000423	putative glycosyl transferase; Provisional; Region: PRK10073
1133852000424	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1133852000425	active site
1133852000426	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1133852000427	NodB motif; other site
1133852000428	putative active site [active]
1133852000429	putative catalytic site [active]
1133852000430	Zn binding site [ion binding]; other site
1133852000431	AmiB activator; Provisional; Region: PRK11637
1133852000432	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1133852000433	HemX; Region: HemX; cl19375
1133852000434	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133852000435	phosphoglyceromutase; Provisional; Region: PRK05434
1133852000436	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1133852000437	active site residue [active]
1133852000438	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1133852000439	GSH binding site [chemical binding]; other site
1133852000440	catalytic residues [active]
1133852000441	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1133852000442	SecA binding site; other site
1133852000443	Preprotein binding site; other site
1133852000444	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1133852000445	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1133852000446	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1133852000447	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1133852000448	Serine acetyltransferase, N-terminal; Region: SATase_N; smart00971
1133852000449	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1133852000450	trimer interface [polypeptide binding]; other site
1133852000451	active site
1133852000452	substrate binding site [chemical binding]; other site
1133852000453	CoA binding site [chemical binding]; other site
1133852000454	putative rRNA methylase; Provisional; Region: PRK10358
1133852000455	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1133852000456	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1133852000457	active site
1133852000458	substrate binding site [chemical binding]; other site
1133852000459	FMN binding site [chemical binding]; other site
1133852000460	putative catalytic residues [active]
1133852000461	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1133852000462	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852000463	DNA-binding site [nucleotide binding]; DNA binding site
1133852000464	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852000465	L-lactate permease; Provisional; Region: PRK10420
1133852000466	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852000467	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1133852000468	trimer interface [polypeptide binding]; other site
1133852000469	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1133852000470	trimer interface [polypeptide binding]; other site
1133852000471	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1133852000472	trimer interface [polypeptide binding]; other site
1133852000473	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1133852000474	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1133852000475	trimer interface [polypeptide binding]; other site
1133852000476	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1133852000477	trimer interface [polypeptide binding]; other site
1133852000478	Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662
1133852000479	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1133852000480	Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662
1133852000481	YadA-like C-terminal region; Region: YadA_anchor; pfam03895
1133852000482	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1133852000483	hypothetical protein; Provisional; Region: PRK11020
1133852000484	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1133852000485	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1133852000486	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133852000487	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133852000488	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1133852000489	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1133852000490	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1133852000491	active site
1133852000492	P-loop; other site
1133852000493	phosphorylation site [posttranslational modification]
1133852000494	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852000495	active site
1133852000496	phosphorylation site [posttranslational modification]
1133852000497	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1133852000498	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1133852000499	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852000500	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852000501	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133852000502	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852000503	RHS protein; Region: RHS; pfam03527
1133852000504	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852000505	putative lyase; Provisional; Region: PRK09687
1133852000506	HEAT-like repeat; Region: HEAT_EZ; pfam13513
1133852000507	NTF2 fold immunity protein; Region: Imm-NTF2-2; pfam15631
1133852000508	PAAR motif; Region: PAAR_motif; cl15808
1133852000509	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852000510	RHS Repeat; Region: RHS_repeat; pfam05593
1133852000511	RHS Repeat; Region: RHS_repeat; pfam05593
1133852000512	RHS Repeat; Region: RHS_repeat; pfam05593
1133852000513	RHS Repeat; Region: RHS_repeat; pfam05593
1133852000514	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852000515	RHS Repeat; Region: RHS_repeat; pfam05593
1133852000516	RHS Repeat; Region: RHS_repeat; pfam05593
1133852000517	RHS protein; Region: RHS; pfam03527
1133852000518	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852000519	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1133852000520	putative glutathione S-transferase; Provisional; Region: PRK10357
1133852000521	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1133852000522	putative C-terminal domain interface [polypeptide binding]; other site
1133852000523	putative GSH binding site (G-site) [chemical binding]; other site
1133852000524	putative dimer interface [polypeptide binding]; other site
1133852000525	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1133852000526	dimer interface [polypeptide binding]; other site
1133852000527	N-terminal domain interface [polypeptide binding]; other site
1133852000528	putative substrate binding pocket (H-site) [chemical binding]; other site
1133852000529	selenocysteine synthase; Provisional; Region: PRK04311
1133852000530	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1133852000531	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1133852000532	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852000533	catalytic residue [active]
1133852000534	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1133852000535	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1133852000536	G1 box; other site
1133852000537	putative GEF interaction site [polypeptide binding]; other site
1133852000538	GTP/Mg2+ binding site [chemical binding]; other site
1133852000539	Switch I region; other site
1133852000540	G2 box; other site
1133852000541	G3 box; other site
1133852000542	Switch II region; other site
1133852000543	G4 box; other site
1133852000544	G5 box; other site
1133852000545	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1133852000546	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1133852000547	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1133852000548	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1133852000549	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1133852000550	dimer interface [polypeptide binding]; other site
1133852000551	active site
1133852000552	metal binding site [ion binding]; metal-binding site
1133852000553	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II and Staphylococcus aureus AldA1 (SACOL0154)-like; Region: ALDH_ACDHII_AcoD-like; cd07559
1133852000554	NAD(P) binding site [chemical binding]; other site
1133852000555	catalytic residues [active]
1133852000556	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1133852000557	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1133852000558	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852000559	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852000560	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852000561	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852000562	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852000563	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1133852000564	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133852000565	intersubunit interface [polypeptide binding]; other site
1133852000566	active site
1133852000567	Zn2+ binding site [ion binding]; other site
1133852000568	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1133852000569	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1133852000570	AP (apurinic/apyrimidinic) site pocket; other site
1133852000571	DNA interaction; other site
1133852000572	Metal-binding active site; metal-binding site
1133852000573	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1133852000574	active site
1133852000575	dimer interface [polypeptide binding]; other site
1133852000576	magnesium binding site [ion binding]; other site
1133852000577	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1133852000578	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1133852000579	putative N- and C-terminal domain interface [polypeptide binding]; other site
1133852000580	putative active site [active]
1133852000581	MgATP binding site [chemical binding]; other site
1133852000582	catalytic site [active]
1133852000583	metal binding site [ion binding]; metal-binding site
1133852000584	putative xylulose binding site [chemical binding]; other site
1133852000585	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1133852000586	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1133852000587	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1133852000588	DctM-like transporters; Region: DctM; pfam06808
1133852000589	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1133852000590	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
1133852000591	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1133852000592	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1133852000593	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133852000594	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133852000595	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133852000596	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852000597	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852000598	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1133852000599	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852000600	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852000601	homodimer interface [polypeptide binding]; other site
1133852000602	catalytic residue [active]
1133852000603	potential frameshift: common BLAST hit: gi|218697288|ref|YP_002404955.1| periplasmic alpha-amylase
1133852000604	hypothetical protein; Provisional; Region: PRK10356
1133852000605	Lysozyme subfamily 2; Region: LYZ2; smart00047
1133852000606	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1133852000607	putative dimerization interface [polypeptide binding]; other site
1133852000608	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133852000609	putative ligand binding site [chemical binding]; other site
1133852000610	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000611	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852000612	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000613	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852000614	TM-ABC transporter signature motif; other site
1133852000615	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1133852000616	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852000617	Walker A/P-loop; other site
1133852000618	ATP binding site [chemical binding]; other site
1133852000619	Q-loop/lid; other site
1133852000620	ABC transporter signature motif; other site
1133852000621	Walker B; other site
1133852000622	D-loop; other site
1133852000623	H-loop/switch region; other site
1133852000624	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852000625	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
1133852000626	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1133852000627	putative ligand binding site [chemical binding]; other site
1133852000628	xylose isomerase; Provisional; Region: PRK05474
1133852000629	xylulokinase; Provisional; Region: PRK15027
1133852000630	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1133852000631	N- and C-terminal domain interface [polypeptide binding]; other site
1133852000632	active site
1133852000633	MgATP binding site [chemical binding]; other site
1133852000634	catalytic site [active]
1133852000635	metal binding site [ion binding]; metal-binding site
1133852000636	xylulose binding site [chemical binding]; other site
1133852000637	homodimer interface [polypeptide binding]; other site
1133852000638	hypothetical protein; Provisional; Region: PRK11403
1133852000639	yiaA/B two helix domain; Region: YiaAB; pfam05360
1133852000640	hypothetical protein; Provisional; Region: PRK11383
1133852000641	yiaA/B two helix domain; Region: YiaAB; pfam05360
1133852000642	yiaA/B two helix domain; Region: YiaAB; pfam05360
1133852000643	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1133852000644	YsaB-like lipoprotein; Region: YsaB; pfam13983
1133852000645	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1133852000646	dimer interface [polypeptide binding]; other site
1133852000647	motif 1; other site
1133852000648	active site
1133852000649	motif 2; other site
1133852000650	motif 3; other site
1133852000651	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
1133852000652	Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092
1133852000653	DALR anticodon binding domain; Region: DALR_1; pfam05746
1133852000654	anticodon binding site; other site
1133852000655	tRNA binding surface [nucleotide binding]; other site
1133852000656	small toxic polypeptide; Provisional; Region: PRK09759
1133852000657	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133852000658	DNA-binding site [nucleotide binding]; DNA binding site
1133852000659	RNA-binding motif; other site
1133852000660	Predicted transcriptional regulator [Transcription]; Region: COG2944
1133852000661	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852000662	non-specific DNA binding site [nucleotide binding]; other site
1133852000663	salt bridge; other site
1133852000664	sequence-specific DNA binding site [nucleotide binding]; other site
1133852000665	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1133852000666	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1133852000667	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1133852000668	dimerization interface [polypeptide binding]; other site
1133852000669	ligand binding site [chemical binding]; other site
1133852000670	NADP binding site [chemical binding]; other site
1133852000671	catalytic site [active]
1133852000672	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1133852000673	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1133852000674	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133852000675	ligand binding site [chemical binding]; other site
1133852000676	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1133852000677	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1133852000678	molybdopterin cofactor binding site [chemical binding]; other site
1133852000679	substrate binding site [chemical binding]; other site
1133852000680	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1133852000681	molybdopterin cofactor binding site; other site
1133852000682	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133852000683	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852000684	Coenzyme A binding pocket [chemical binding]; other site
1133852000685	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1133852000686	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1133852000687	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1133852000688	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000689	putative substrate translocation pore; other site
1133852000690	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1133852000691	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1133852000692	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852000693	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852000694	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
1133852000695	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852000696	Outer membrane usher protein; Region: Usher; pfam00577
1133852000697	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852000698	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
1133852000699	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
1133852000700	phosphoethanolamine transferase; Provisional; Region: PRK11560
1133852000701	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1133852000702	Sulfatase; Region: Sulfatase; pfam00884
1133852000703	antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109
1133852000704	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1133852000705	peptide binding site [polypeptide binding]; other site
1133852000706	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1133852000707	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852000708	dimer interface [polypeptide binding]; other site
1133852000709	conserved gate region; other site
1133852000710	putative PBP binding loops; other site
1133852000711	ABC-ATPase subunit interface; other site
1133852000712	dipeptide transporter; Provisional; Region: PRK10913
1133852000713	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133852000714	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852000715	dimer interface [polypeptide binding]; other site
1133852000716	conserved gate region; other site
1133852000717	putative PBP binding loops; other site
1133852000718	ABC-ATPase subunit interface; other site
1133852000719	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1133852000720	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852000721	Walker A/P-loop; other site
1133852000722	ATP binding site [chemical binding]; other site
1133852000723	Q-loop/lid; other site
1133852000724	ABC transporter signature motif; other site
1133852000725	Walker B; other site
1133852000726	D-loop; other site
1133852000727	H-loop/switch region; other site
1133852000728	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852000729	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1133852000730	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852000731	Walker A/P-loop; other site
1133852000732	ATP binding site [chemical binding]; other site
1133852000733	Q-loop/lid; other site
1133852000734	ABC transporter signature motif; other site
1133852000735	Walker B; other site
1133852000736	D-loop; other site
1133852000737	H-loop/switch region; other site
1133852000738	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852000739	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852000740	serine transporter; Region: stp; TIGR00814
1133852000741	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133852000742	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133852000743	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
1133852000744	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
1133852000745	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1133852000746	cell division protein; Provisional; Region: PRK10037
1133852000747	YhjQ protein; Region: YhjQ; pfam06564
1133852000748	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1133852000749	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1133852000750	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1133852000751	DXD motif; other site
1133852000752	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1133852000753	PilZ domain; Region: PilZ; pfam07238
1133852000754	cellulose synthase regulator protein; Provisional; Region: PRK11114
1133852000755	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1133852000756	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1133852000757	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852000758	binding surface
1133852000759	TPR motif; other site
1133852000760	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852000761	binding surface
1133852000762	TPR motif; other site
1133852000763	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1133852000764	putative diguanylate cyclase; Provisional; Region: PRK13561
1133852000765	HAMP domain; Region: HAMP; pfam00672
1133852000766	diguanylate cyclase; Region: GGDEF; smart00267
1133852000767	metal binding site [ion binding]; metal-binding site
1133852000768	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852000769	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1133852000770	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1133852000771	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133852000772	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1133852000773	substrate binding site [chemical binding]; other site
1133852000774	ATP binding site [chemical binding]; other site
1133852000775	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852000776	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1133852000777	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133852000778	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000779	metabolite-proton symporter; Region: 2A0106; TIGR00883
1133852000780	putative substrate translocation pore; other site
1133852000781	inner membrane protein YhjD; Region: TIGR00766
1133852000782	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852000783	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852000784	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1133852000785	putative effector binding pocket; other site
1133852000786	putative dimerization interface [polypeptide binding]; other site
1133852000787	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852000788	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852000789	DNA binding residues [nucleotide binding]
1133852000790	dimerization interface [polypeptide binding]; other site
1133852000791	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1133852000792	trehalase; Provisional; Region: treF; PRK13270
1133852000793	Haem-binding domain; Region: Haem_bd; pfam14376
1133852000794	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1133852000795	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
1133852000796	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1133852000797	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852000798	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1133852000799	catalytic residue [active]
1133852000800	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1133852000801	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000802	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000803	transcriptional regulator YdeO; Provisional; Region: PRK09940
1133852000804	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000805	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852000806	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1133852000807	MMPL family; Region: MMPL; cl14618
1133852000808	MMPL family; Region: MMPL; cl14618
1133852000809	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
1133852000810	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852000811	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852000812	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
1133852000813	acid-resistance membrane protein; Provisional; Region: PRK10209
1133852000814	acid-resistance protein; Provisional; Region: PRK10208
1133852000815	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1133852000816	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1133852000817	MgtC family; Region: MgtC; pfam02308
1133852000818	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852000819	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852000820	DNA binding residues [nucleotide binding]
1133852000821	dimerization interface [polypeptide binding]; other site
1133852000822	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
1133852000823	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1133852000824	Predicted permeases [General function prediction only]; Region: COG0701
1133852000825	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852000826	dimerization interface [polypeptide binding]; other site
1133852000827	putative DNA binding site [nucleotide binding]; other site
1133852000828	putative Zn2+ binding site [ion binding]; other site
1133852000829	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1133852000830	catalytic residues [active]
1133852000831	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1133852000832	Citrate transporter; Region: CitMHS; pfam03600
1133852000833	transmembrane helices; other site
1133852000834	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852000835	dimerization interface [polypeptide binding]; other site
1133852000836	putative DNA binding site [nucleotide binding]; other site
1133852000837	putative Zn2+ binding site [ion binding]; other site
1133852000838	glutathione reductase; Validated; Region: PRK06116
1133852000839	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852000840	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852000841	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1133852000842	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1133852000843	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
1133852000844	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1133852000845	active site
1133852000846	Zn binding site [ion binding]; other site
1133852000847	putative methyltransferase; Provisional; Region: PRK10742
1133852000848	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852000849	S-adenosylmethionine binding site [chemical binding]; other site
1133852000850	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133852000851	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852000852	putative substrate translocation pore; other site
1133852000853	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852000854	Ligand Binding Site [chemical binding]; other site
1133852000855	universal stress protein UspB; Provisional; Region: PRK04960
1133852000856	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1133852000857	Predicted flavoproteins [General function prediction only]; Region: COG2081
1133852000858	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852000859	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
1133852000860	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
1133852000861	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1133852000862	AAA domain; Region: AAA_22; pfam13401
1133852000863	TniQ; Region: TniQ; pfam06527
1133852000864	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852000865	salt bridge; other site
1133852000866	non-specific DNA binding site [nucleotide binding]; other site
1133852000867	sequence-specific DNA binding site [nucleotide binding]; other site
1133852000868	AAA ATPase domain; Region: AAA_15; pfam13175
1133852000869	AAA domain; Region: AAA_23; pfam13476
1133852000870	Walker A/P-loop; other site
1133852000871	ATP binding site [chemical binding]; other site
1133852000872	AAA domain; Region: AAA_21; pfam13304
1133852000873	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1133852000874	active site
1133852000875	metal binding site [ion binding]; metal-binding site
1133852000876	Domain of unknown function (DUF305); Region: DUF305; cl17794
1133852000877	sensor kinase CusS; Provisional; Region: PRK09835
1133852000878	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852000879	dimerization interface [polypeptide binding]; other site
1133852000880	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852000881	dimer interface [polypeptide binding]; other site
1133852000882	phosphorylation site [posttranslational modification]
1133852000883	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852000884	ATP binding site [chemical binding]; other site
1133852000885	Mg2+ binding site [ion binding]; other site
1133852000886	G-X-G motif; other site
1133852000887	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
1133852000888	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852000889	active site
1133852000890	phosphorylation site [posttranslational modification]
1133852000891	intermolecular recognition site; other site
1133852000892	dimerization interface [polypeptide binding]; other site
1133852000893	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852000894	DNA binding site [nucleotide binding]
1133852000895	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1133852000896	Outer membrane efflux protein; Region: OEP; pfam02321
1133852000897	Outer membrane efflux protein; Region: OEP; pfam02321
1133852000898	periplasmic copper-binding protein; Provisional; Region: PRK09838
1133852000899	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1133852000900	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852000901	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1133852000902	Protein of unknown function, DUF; Region: DUF411; cl01142
1133852000903	YHS domain; Region: YHS; pfam04945
1133852000904	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
1133852000905	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133852000906	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852000907	motif II; other site
1133852000908	Protein of unknown function (DUF2933); Region: DUF2933; pfam11666
1133852000909	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133852000910	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133852000911	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
1133852000912	The first cupredoxin domain of CopA copper resistance protein family; Region: CuRO_1_CopA; cd13848
1133852000913	putative Domain 2 interface [polypeptide binding]; other site
1133852000914	putative Domain 3 interface [polypeptide binding]; other site
1133852000915	trinuclear Cu binding site [ion binding]; other site
1133852000916	The second cupredoxin domain of  CopA copper resistance protein family; Region: CuRO_2_CopA; cd13874
1133852000917	putative Domain 1 interface [polypeptide binding]; other site
1133852000918	putative Domain 3 interface [polypeptide binding]; other site
1133852000919	The third cupredoxin domain of CopA copper resistance protein family; Region: CuRO_3_CopA; cd13896
1133852000920	putative Domain 2 interface [polypeptide binding]; other site
1133852000921	Type 1 (T1) Cu binding site [ion binding]; other site
1133852000922	putative Domain 1 interface [polypeptide binding]; other site
1133852000923	trinuclear Cu binding site [ion binding]; other site
1133852000924	Copper resistance protein B precursor (CopB); Region: CopB; pfam05275
1133852000925	CopC domain; Region: CopC; pfam04234
1133852000926	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1133852000927	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
1133852000928	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852000929	active site
1133852000930	phosphorylation site [posttranslational modification]
1133852000931	intermolecular recognition site; other site
1133852000932	dimerization interface [polypeptide binding]; other site
1133852000933	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852000934	DNA binding site [nucleotide binding]
1133852000935	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1133852000936	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852000937	dimerization interface [polypeptide binding]; other site
1133852000938	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852000939	dimer interface [polypeptide binding]; other site
1133852000940	phosphorylation site [posttranslational modification]
1133852000941	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852000942	ATP binding site [chemical binding]; other site
1133852000943	Mg2+ binding site [ion binding]; other site
1133852000944	G-X-G motif; other site
1133852000945	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
1133852000946	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
1133852000947	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
1133852000948	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1133852000949	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852000950	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852000951	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1133852000952	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133852000953	Walker A/P-loop; other site
1133852000954	ATP binding site [chemical binding]; other site
1133852000955	Q-loop/lid; other site
1133852000956	ABC transporter signature motif; other site
1133852000957	Walker B; other site
1133852000958	D-loop; other site
1133852000959	H-loop/switch region; other site
1133852000960	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852000961	Walker A/P-loop; other site
1133852000962	ATP binding site [chemical binding]; other site
1133852000963	Q-loop/lid; other site
1133852000964	ABC transporter signature motif; other site
1133852000965	Walker B; other site
1133852000966	D-loop; other site
1133852000967	H-loop/switch region; other site
1133852000968	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133852000969	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1133852000970	Structural glycoprotein p40/gp41 conserved region; Region: Baculo_gp41; pfam04700
1133852000971	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133852000972	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1133852000973	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1133852000974	HicB family; Region: HicB; pfam05534
1133852000975	nickel responsive regulator; Provisional; Region: PRK02967
1133852000976	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1133852000977	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
1133852000978	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852000979	Walker A/P-loop; other site
1133852000980	ATP binding site [chemical binding]; other site
1133852000981	Q-loop/lid; other site
1133852000982	ABC transporter signature motif; other site
1133852000983	Walker B; other site
1133852000984	D-loop; other site
1133852000985	H-loop/switch region; other site
1133852000986	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
1133852000987	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852000988	Walker A/P-loop; other site
1133852000989	ATP binding site [chemical binding]; other site
1133852000990	Q-loop/lid; other site
1133852000991	ABC transporter signature motif; other site
1133852000992	Walker B; other site
1133852000993	D-loop; other site
1133852000994	H-loop/switch region; other site
1133852000995	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852000996	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
1133852000997	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852000998	dimer interface [polypeptide binding]; other site
1133852000999	conserved gate region; other site
1133852001000	putative PBP binding loops; other site
1133852001001	ABC-ATPase subunit interface; other site
1133852001002	nickel transporter permease NikB; Provisional; Region: PRK10352
1133852001003	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852001004	dimer interface [polypeptide binding]; other site
1133852001005	conserved gate region; other site
1133852001006	putative PBP binding loops; other site
1133852001007	ABC-ATPase subunit interface; other site
1133852001008	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1133852001009	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1133852001010	substrate binding site [chemical binding]; other site
1133852001011	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1133852001012	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1133852001013	Domain of unknown function DUF20; Region: UPF0118; cl00465
1133852001014	major facilitator superfamily transporter; Provisional; Region: PRK05122
1133852001015	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852001016	putative substrate translocation pore; other site
1133852001017	hypothetical protein; Provisional; Region: PRK11615
1133852001018	hypothetical protein; Provisional; Region: PRK11212
1133852001019	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1133852001020	CPxP  motif; other site
1133852001021	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1133852001022	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133852001023	metal-binding site [ion binding]
1133852001024	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133852001025	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1133852001026	Predicted membrane protein [Function unknown]; Region: COG3714
1133852001027	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1133852001028	hypothetical protein; Provisional; Region: PRK10910
1133852001029	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852001030	S-adenosylmethionine binding site [chemical binding]; other site
1133852001031	Mitochondria Localisation Sequence; Region: AIF-MLS; pfam14962
1133852001032	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1133852001033	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1133852001034	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1133852001035	P loop; other site
1133852001036	GTP binding site [chemical binding]; other site
1133852001037	cell division protein FtsE; Provisional; Region: PRK10908
1133852001038	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852001039	Walker A/P-loop; other site
1133852001040	ATP binding site [chemical binding]; other site
1133852001041	Q-loop/lid; other site
1133852001042	ABC transporter signature motif; other site
1133852001043	Walker B; other site
1133852001044	D-loop; other site
1133852001045	H-loop/switch region; other site
1133852001046	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1133852001047	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1133852001048	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1133852001049	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133852001050	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133852001051	DNA binding residues [nucleotide binding]
1133852001052	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1133852001053	dimerization interface [polypeptide binding]; other site
1133852001054	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
1133852001055	ligand binding site [chemical binding]; other site
1133852001056	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852001057	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1133852001058	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1133852001059	dimerization interface [polypeptide binding]; other site
1133852001060	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
1133852001061	ligand binding site [chemical binding]; other site
1133852001062	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1133852001063	TM-ABC transporter signature motif; other site
1133852001064	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1133852001065	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1133852001066	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1133852001067	TM-ABC transporter signature motif; other site
1133852001068	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1133852001069	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1133852001070	Walker A/P-loop; other site
1133852001071	ATP binding site [chemical binding]; other site
1133852001072	Q-loop/lid; other site
1133852001073	ABC transporter signature motif; other site
1133852001074	Walker B; other site
1133852001075	D-loop; other site
1133852001076	H-loop/switch region; other site
1133852001077	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1133852001078	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1133852001079	Walker A/P-loop; other site
1133852001080	ATP binding site [chemical binding]; other site
1133852001081	Q-loop/lid; other site
1133852001082	ABC transporter signature motif; other site
1133852001083	Walker B; other site
1133852001084	D-loop; other site
1133852001085	H-loop/switch region; other site
1133852001086	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852001087	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1133852001088	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1133852001089	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1133852001090	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852001091	dimer interface [polypeptide binding]; other site
1133852001092	conserved gate region; other site
1133852001093	putative PBP binding loops; other site
1133852001094	ABC-ATPase subunit interface; other site
1133852001095	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1133852001096	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852001097	dimer interface [polypeptide binding]; other site
1133852001098	conserved gate region; other site
1133852001099	putative PBP binding loops; other site
1133852001100	ABC-ATPase subunit interface; other site
1133852001101	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1133852001102	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1133852001103	Walker A/P-loop; other site
1133852001104	ATP binding site [chemical binding]; other site
1133852001105	Q-loop/lid; other site
1133852001106	ABC transporter signature motif; other site
1133852001107	Walker B; other site
1133852001108	D-loop; other site
1133852001109	H-loop/switch region; other site
1133852001110	TOBE domain; Region: TOBE_2; pfam08402
1133852001111	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1133852001112	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1133852001113	putative active site [active]
1133852001114	catalytic site [active]
1133852001115	putative metal binding site [ion binding]; other site
1133852001116	hypothetical protein; Provisional; Region: PRK10350
1133852001117	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1133852001118	Immunity protein 19; Region: Imm19; pfam15567
1133852001119	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1133852001120	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1133852001121	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852001122	Coenzyme A binding pocket [chemical binding]; other site
1133852001123	putative oxidoreductase; Provisional; Region: PRK10206
1133852001124	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133852001125	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133852001126	Pirin-related protein [General function prediction only]; Region: COG1741
1133852001127	Pirin; Region: Pirin; pfam02678
1133852001128	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1133852001129	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852001130	DNA binding site [nucleotide binding]
1133852001131	domain linker motif; other site
1133852001132	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1133852001133	putative ligand binding site [chemical binding]; other site
1133852001134	putative dimerization interface [polypeptide binding]; other site
1133852001135	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1133852001136	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1133852001137	ATP-binding site [chemical binding]; other site
1133852001138	Gluconate-6-phosphate binding site [chemical binding]; other site
1133852001139	low affinity gluconate transporter; Provisional; Region: PRK10472
1133852001140	GntP family permease; Region: GntP_permease; pfam02447
1133852001141	putative antibiotic transporter; Provisional; Region: PRK10739
1133852001142	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1133852001143	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
1133852001144	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
1133852001145	glycogen branching enzyme; Provisional; Region: PRK05402
1133852001146	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1133852001147	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1133852001148	active site
1133852001149	catalytic site [active]
1133852001150	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1133852001151	glycogen debranching enzyme; Provisional; Region: PRK03705
1133852001152	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1133852001153	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1133852001154	active site
1133852001155	catalytic site [active]
1133852001156	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1133852001157	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1133852001158	ligand binding site; other site
1133852001159	oligomer interface; other site
1133852001160	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1133852001161	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1133852001162	dimer interface [polypeptide binding]; other site
1133852001163	N-terminal domain interface [polypeptide binding]; other site
1133852001164	sulfate 1 binding site; other site
1133852001165	glycogen synthase; Provisional; Region: glgA; PRK00654
1133852001166	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1133852001167	ADP-binding pocket [chemical binding]; other site
1133852001168	homodimer interface [polypeptide binding]; other site
1133852001169	glycogen phosphorylase; Provisional; Region: PRK14986
1133852001170	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1133852001171	homodimer interface [polypeptide binding]; other site
1133852001172	active site pocket [active]
1133852001173	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1133852001174	hypothetical protein; Provisional; Region: PRK09781; cl08057
1133852001175	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1133852001176	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1133852001177	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1133852001178	active site residue [active]
1133852001179	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1133852001180	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1133852001181	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1133852001182	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1133852001183	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852001184	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852001185	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1133852001186	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1133852001187	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852001188	Walker A motif; other site
1133852001189	ATP binding site [chemical binding]; other site
1133852001190	Walker B motif; other site
1133852001191	arginine finger; other site
1133852001192	Uncharacterized conserved protein [Function unknown]; Region: RtcB; COG1690
1133852001193	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
1133852001194	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
1133852001195	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
1133852001196	putative active site [active]
1133852001197	transcriptional regulator MalT; Provisional; Region: PRK04841
1133852001198	AAA ATPase domain; Region: AAA_16; pfam13191
1133852001199	Cohesin loading factor; Region: Cohesin_load; pfam10345
1133852001200	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852001201	DNA binding residues [nucleotide binding]
1133852001202	dimerization interface [polypeptide binding]; other site
1133852001203	maltodextrin phosphorylase; Provisional; Region: PRK14985
1133852001204	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1133852001205	homodimer interface [polypeptide binding]; other site
1133852001206	active site pocket [active]
1133852001207	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1133852001208	4-alpha-glucanotransferase; Region: malQ; TIGR00217
1133852001209	high-affinity gluconate transporter; Provisional; Region: PRK14984
1133852001210	GntP family permease; Region: GntP_permease; pfam02447
1133852001211	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1133852001212	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1133852001213	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1133852001214	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1133852001215	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852001216	active site
1133852001217	carboxylesterase BioH; Provisional; Region: PRK10349
1133852001218	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1133852001219	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1133852001220	putative transposase; Provisional; Region: PRK09857
1133852001221	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133852001222	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1133852001223	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1133852001224	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1133852001225	G1 box; other site
1133852001226	GTP/Mg2+ binding site [chemical binding]; other site
1133852001227	Switch I region; other site
1133852001228	G2 box; other site
1133852001229	G3 box; other site
1133852001230	Switch II region; other site
1133852001231	G4 box; other site
1133852001232	G5 box; other site
1133852001233	Nucleoside recognition; Region: Gate; pfam07670
1133852001234	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1133852001235	Nucleoside recognition; Region: Gate; pfam07670
1133852001236	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1133852001237	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1133852001238	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1133852001239	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1133852001240	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1133852001241	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1133852001242	RNA binding site [nucleotide binding]; other site
1133852001243	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1133852001244	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1133852001245	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1133852001246	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1133852001247	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852001248	active site
1133852001249	phosphorylation site [posttranslational modification]
1133852001250	intermolecular recognition site; other site
1133852001251	dimerization interface [polypeptide binding]; other site
1133852001252	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852001253	DNA binding site [nucleotide binding]
1133852001254	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1133852001255	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852001256	dimerization interface [polypeptide binding]; other site
1133852001257	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852001258	dimer interface [polypeptide binding]; other site
1133852001259	phosphorylation site [posttranslational modification]
1133852001260	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852001261	ATP binding site [chemical binding]; other site
1133852001262	Mg2+ binding site [ion binding]; other site
1133852001263	G-X-G motif; other site
1133852001264	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852001265	non-specific DNA binding site [nucleotide binding]; other site
1133852001266	salt bridge; other site
1133852001267	sequence-specific DNA binding site [nucleotide binding]; other site
1133852001268	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1133852001269	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1133852001270	active site
1133852001271	substrate-binding site [chemical binding]; other site
1133852001272	metal-binding site [ion binding]
1133852001273	ATP binding site [chemical binding]; other site
1133852001274	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1133852001275	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1133852001276	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1133852001277	dimerization interface [polypeptide binding]; other site
1133852001278	domain crossover interface; other site
1133852001279	redox-dependent activation switch; other site
1133852001280	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852001281	RNA binding surface [nucleotide binding]; other site
1133852001282	GMP/IMP nucleotidase; Provisional; Region: PRK14988
1133852001283	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1133852001284	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852001285	motif II; other site
1133852001286	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1133852001287	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1133852001288	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1133852001289	ADP-ribose binding site [chemical binding]; other site
1133852001290	dimer interface [polypeptide binding]; other site
1133852001291	active site
1133852001292	nudix motif; other site
1133852001293	metal binding site [ion binding]; metal-binding site
1133852001294	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1133852001295	Transglycosylase; Region: Transgly; pfam00912
1133852001296	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1133852001297	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1133852001298	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1133852001299	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1133852001300	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1133852001301	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133852001302	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1133852001303	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1133852001304	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1133852001305	ADP binding site [chemical binding]; other site
1133852001306	magnesium binding site [ion binding]; other site
1133852001307	putative shikimate binding site; other site
1133852001308	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1133852001309	active site
1133852001310	dimer interface [polypeptide binding]; other site
1133852001311	metal binding site [ion binding]; metal-binding site
1133852001312	cell division protein DamX; Validated; Region: PRK10905
1133852001313	Sporulation related domain; Region: SPOR; pfam05036
1133852001314	DNA adenine methylase; Provisional; Region: PRK10904
1133852001315	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1133852001316	substrate binding site [chemical binding]; other site
1133852001317	hexamer interface [polypeptide binding]; other site
1133852001318	metal binding site [ion binding]; metal-binding site
1133852001319	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852001320	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1133852001321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852001322	motif II; other site
1133852001323	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927
1133852001324	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1133852001325	active site
1133852001326	HIGH motif; other site
1133852001327	dimer interface [polypeptide binding]; other site
1133852001328	KMSKS motif; other site
1133852001329	Helix-turn-helix domain; Region: HTH_41; pfam14502
1133852001330	YhfZ C-terminal domain; Region: YhfZ_C; pfam14503
1133852001331	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1133852001332	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
1133852001333	dimer interface [polypeptide binding]; other site
1133852001334	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1133852001335	active site
1133852001336	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133852001337	substrate binding site [chemical binding]; other site
1133852001338	catalytic residue [active]
1133852001339	putative mutase; Provisional; Region: PRK12383
1133852001340	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1133852001341	active site
1133852001342	substrate binding pocket [chemical binding]; other site
1133852001343	homodimer interaction site [polypeptide binding]; other site
1133852001344	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
1133852001345	Protein of unknown function; Region: YhfT; pfam10797
1133852001346	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1133852001347	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852001348	catalytic residue [active]
1133852001349	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
1133852001350	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852001351	DNA-binding site [nucleotide binding]; DNA binding site
1133852001352	UTRA domain; Region: UTRA; pfam07702
1133852001353	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1133852001354	substrate binding site [chemical binding]; other site
1133852001355	ATP binding site [chemical binding]; other site
1133852001356	fructoselysine 3-epimerase; Provisional; Region: PRK09856
1133852001357	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1133852001358	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
1133852001359	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1133852001360	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1133852001361	dimer interface [polypeptide binding]; other site
1133852001362	active site
1133852001363	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
1133852001364	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852001365	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1133852001366	siroheme synthase; Provisional; Region: cysG; PRK10637
1133852001367	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1133852001368	Sirohaem biosynthesis protein central; Region: Sirohm_synth_M; pfam14824
1133852001369	Sirohaem synthase dimerization region; Region: CysG_dimeriser; pfam10414
1133852001370	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1133852001371	active site
1133852001372	SAM binding site [chemical binding]; other site
1133852001373	homodimer interface [polypeptide binding]; other site
1133852001374	nitrite transporter NirC; Provisional; Region: PRK11562
1133852001375	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1133852001376	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1133852001377	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852001378	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1133852001379	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1133852001380	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
1133852001381	putative transporter; Provisional; Region: PRK03699
1133852001382	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852001383	putative substrate translocation pore; other site
1133852001384	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1133852001385	substrate binding site [chemical binding]; other site
1133852001386	Protein of unknown function (DUF2559); Region: DUF2559; pfam10832
1133852001387	cell filamentation protein Fic; Provisional; Region: PRK10347
1133852001388	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1133852001389	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1133852001390	glutamine binding [chemical binding]; other site
1133852001391	catalytic triad [active]
1133852001392	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1133852001393	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852001394	inhibitor-cofactor binding pocket; inhibition site
1133852001395	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852001396	catalytic residue [active]
1133852001397	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1133852001398	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1133852001399	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133852001400	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1133852001401	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1133852001402	ligand binding site [chemical binding]; other site
1133852001403	flexible hinge region; other site
1133852001404	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1133852001405	putative switch regulator; other site
1133852001406	non-specific DNA interactions [nucleotide binding]; other site
1133852001407	DNA binding site [nucleotide binding]
1133852001408	sequence specific DNA binding site [nucleotide binding]; other site
1133852001409	putative cAMP binding site [chemical binding]; other site
1133852001410	hypothetical protein; Provisional; Region: PRK10738
1133852001411	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1133852001412	active site
1133852001413	hypothetical protein; Provisional; Region: PRK04966
1133852001414	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
1133852001415	putative hydrolase; Provisional; Region: PRK10985
1133852001416	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1133852001417	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852001418	ABC transporter; Region: ABC_tran_2; pfam12848
1133852001419	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852001420	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1133852001421	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1133852001422	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1133852001423	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1133852001424	TrkA-N domain; Region: TrkA_N; pfam02254
1133852001425	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1133852001426	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
1133852001427	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
1133852001428	phi X174 lysis protein; Provisional; Region: PRK02793
1133852001429	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1133852001430	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1133852001431	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133852001432	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1133852001433	YheO-like PAS domain; Region: PAS_6; pfam08348
1133852001434	HTH domain; Region: HTH_22; pfam13309
1133852001435	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1133852001436	sulfur relay protein TusC; Validated; Region: PRK00211
1133852001437	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1133852001438	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1133852001439	S17 interaction site [polypeptide binding]; other site
1133852001440	S8 interaction site; other site
1133852001441	16S rRNA interaction site [nucleotide binding]; other site
1133852001442	streptomycin interaction site [chemical binding]; other site
1133852001443	23S rRNA interaction site [nucleotide binding]; other site
1133852001444	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1133852001445	30S ribosomal protein S7; Validated; Region: PRK05302
1133852001446	elongation factor G; Reviewed; Region: PRK00007
1133852001447	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1133852001448	G1 box; other site
1133852001449	putative GEF interaction site [polypeptide binding]; other site
1133852001450	GTP/Mg2+ binding site [chemical binding]; other site
1133852001451	Switch I region; other site
1133852001452	G2 box; other site
1133852001453	G3 box; other site
1133852001454	Switch II region; other site
1133852001455	G4 box; other site
1133852001456	G5 box; other site
1133852001457	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1133852001458	Elongation Factor G, domain II; Region: EFG_II; pfam14492
1133852001459	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1133852001460	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1133852001461	elongation factor Tu; Reviewed; Region: PRK00049
1133852001462	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1133852001463	G1 box; other site
1133852001464	GEF interaction site [polypeptide binding]; other site
1133852001465	GTP/Mg2+ binding site [chemical binding]; other site
1133852001466	Switch I region; other site
1133852001467	G2 box; other site
1133852001468	G3 box; other site
1133852001469	Switch II region; other site
1133852001470	G4 box; other site
1133852001471	G5 box; other site
1133852001472	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1133852001473	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1133852001474	Antibiotic Binding Site [chemical binding]; other site
1133852001475	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1133852001476	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1133852001477	Ferritin-like domain; Region: Ferritin; pfam00210
1133852001478	heme binding site [chemical binding]; other site
1133852001479	ferroxidase pore; other site
1133852001480	ferroxidase diiron center [ion binding]; other site
1133852001481	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1133852001482	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1133852001483	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1133852001484	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1133852001485	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1133852001486	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1133852001487	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1133852001488	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1133852001489	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1133852001490	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1133852001491	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1133852001492	protein-rRNA interface [nucleotide binding]; other site
1133852001493	putative translocon binding site; other site
1133852001494	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1133852001495	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1133852001496	G-X-X-G motif; other site
1133852001497	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1133852001498	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1133852001499	23S rRNA interface [nucleotide binding]; other site
1133852001500	5S rRNA interface [nucleotide binding]; other site
1133852001501	putative antibiotic binding site [chemical binding]; other site
1133852001502	L25 interface [polypeptide binding]; other site
1133852001503	L27 interface [polypeptide binding]; other site
1133852001504	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1133852001505	23S rRNA interface [nucleotide binding]; other site
1133852001506	putative translocon interaction site; other site
1133852001507	signal recognition particle (SRP54) interaction site; other site
1133852001508	L23 interface [polypeptide binding]; other site
1133852001509	trigger factor interaction site; other site
1133852001510	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1133852001511	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1133852001512	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1133852001513	RNA binding site [nucleotide binding]; other site
1133852001514	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1133852001515	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1133852001516	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1133852001517	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1133852001518	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1133852001519	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1133852001520	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1133852001521	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1133852001522	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1133852001523	23S rRNA interface [nucleotide binding]; other site
1133852001524	5S rRNA interface [nucleotide binding]; other site
1133852001525	L27 interface [polypeptide binding]; other site
1133852001526	L5 interface [polypeptide binding]; other site
1133852001527	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1133852001528	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1133852001529	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1133852001530	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1133852001531	23S rRNA binding site [nucleotide binding]; other site
1133852001532	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1133852001533	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1133852001534	SecY translocase; Region: SecY; pfam00344
1133852001535	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1133852001536	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1133852001537	30S ribosomal protein S11; Validated; Region: PRK05309
1133852001538	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1133852001539	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1133852001540	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852001541	RNA binding surface [nucleotide binding]; other site
1133852001542	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1133852001543	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1133852001544	alphaNTD homodimer interface [polypeptide binding]; other site
1133852001545	alphaNTD - beta interaction site [polypeptide binding]; other site
1133852001546	alphaNTD - beta' interaction site [polypeptide binding]; other site
1133852001547	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1133852001548	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1133852001549	hypothetical protein; Provisional; Region: PRK10203
1133852001550	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1133852001551	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1133852001552	DNA binding residues [nucleotide binding]
1133852001553	dimer interface [polypeptide binding]; other site
1133852001554	metal binding site [ion binding]; metal-binding site
1133852001555	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1133852001556	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1133852001557	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1133852001558	TrkA-N domain; Region: TrkA_N; pfam02254
1133852001559	TrkA-C domain; Region: TrkA_C; pfam02080
1133852001560	TrkA-N domain; Region: TrkA_N; pfam02254
1133852001561	TrkA-C domain; Region: TrkA_C; pfam02080
1133852001562	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1133852001563	putative RNA binding site [nucleotide binding]; other site
1133852001564	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1133852001565	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852001566	S-adenosylmethionine binding site [chemical binding]; other site
1133852001567	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1133852001568	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1133852001569	putative active site [active]
1133852001570	substrate binding site [chemical binding]; other site
1133852001571	putative cosubstrate binding site; other site
1133852001572	catalytic site [active]
1133852001573	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1133852001574	substrate binding site [chemical binding]; other site
1133852001575	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1133852001576	active site
1133852001577	catalytic residues [active]
1133852001578	metal binding site [ion binding]; metal-binding site
1133852001579	hypothetical protein; Provisional; Region: PRK10736
1133852001580	DNA protecting protein DprA; Region: dprA; TIGR00732
1133852001581	hypothetical protein; Validated; Region: PRK03430
1133852001582	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1133852001583	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133852001584	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1133852001585	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133852001586	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133852001587	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1133852001588	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
1133852001589	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1133852001590	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1133852001591	shikimate binding site; other site
1133852001592	NAD(P) binding site [chemical binding]; other site
1133852001593	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1133852001594	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1133852001595	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1133852001596	trimer interface [polypeptide binding]; other site
1133852001597	putative metal binding site [ion binding]; other site
1133852001598	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1133852001599	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133852001600	Walker A/P-loop; other site
1133852001601	ATP binding site [chemical binding]; other site
1133852001602	Q-loop/lid; other site
1133852001603	ABC transporter signature motif; other site
1133852001604	Walker B; other site
1133852001605	D-loop; other site
1133852001606	H-loop/switch region; other site
1133852001607	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
1133852001608	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852001609	dimer interface [polypeptide binding]; other site
1133852001610	conserved gate region; other site
1133852001611	putative PBP binding loops; other site
1133852001612	ABC-ATPase subunit interface; other site
1133852001613	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
1133852001614	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1133852001615	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852001616	dimer interface [polypeptide binding]; other site
1133852001617	conserved gate region; other site
1133852001618	putative PBP binding loops; other site
1133852001619	ABC-ATPase subunit interface; other site
1133852001620	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852001621	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1133852001622	substrate binding pocket [chemical binding]; other site
1133852001623	membrane-bound complex binding site; other site
1133852001624	hinge residues; other site
1133852001625	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1133852001626	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1133852001627	MMPL family; Region: MMPL; cl14618
1133852001628	MMPL family; Region: MMPL; cl14618
1133852001629	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1133852001630	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852001631	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852001632	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1133852001633	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852001634	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1133852001635	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1133852001636	putative methyltransferase; Provisional; Region: PRK11524
1133852001637	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852001638	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1133852001639	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1133852001640	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1133852001641	FMN binding site [chemical binding]; other site
1133852001642	active site
1133852001643	catalytic residues [active]
1133852001644	substrate binding site [chemical binding]; other site
1133852001645	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1133852001646	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852001647	S-adenosylmethionine binding site [chemical binding]; other site
1133852001648	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1133852001649	Na binding site [ion binding]; other site
1133852001650	hypothetical protein; Provisional; Region: PRK10633
1133852001651	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1133852001652	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1133852001653	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1133852001654	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1133852001655	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1133852001656	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1133852001657	carboxyltransferase (CT) interaction site; other site
1133852001658	biotinylation site [posttranslational modification]; other site
1133852001659	Ferric reductase like transmembrane component; Region: Ferric_reduct; cl01043
1133852001660	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1133852001661	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1133852001662	NADP binding site [chemical binding]; other site
1133852001663	dimer interface [polypeptide binding]; other site
1133852001664	regulatory protein CsrD; Provisional; Region: PRK11059
1133852001665	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852001666	metal binding site [ion binding]; metal-binding site
1133852001667	active site
1133852001668	I-site; other site
1133852001669	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852001670	rod shape-determining protein MreB; Provisional; Region: PRK13927
1133852001671	MreB and similar proteins; Region: MreB_like; cd10225
1133852001672	nucleotide binding site [chemical binding]; other site
1133852001673	Mg binding site [ion binding]; other site
1133852001674	putative protofilament interaction site [polypeptide binding]; other site
1133852001675	RodZ interaction site [polypeptide binding]; other site
1133852001676	rod shape-determining protein MreC; Region: mreC; TIGR00219
1133852001677	rod shape-determining protein MreD; Provisional; Region: PRK11060
1133852001678	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1133852001679	active site
1133852001680	dimer interface [polypeptide binding]; other site
1133852001681	ribonuclease G; Provisional; Region: PRK11712
1133852001682	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1133852001683	homodimer interface [polypeptide binding]; other site
1133852001684	oligonucleotide binding site [chemical binding]; other site
1133852001685	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1133852001686	hypothetical protein; Provisional; Region: PRK10899
1133852001687	Protein of unknown function; Region: DUF3971; pfam13116
1133852001688	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133852001689	protease TldD; Provisional; Region: tldD; PRK10735
1133852001690	transcriptional regulator; Provisional; Region: PRK10632
1133852001691	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852001692	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1133852001693	putative effector binding pocket; other site
1133852001694	dimerization interface [polypeptide binding]; other site
1133852001695	efflux system membrane protein; Provisional; Region: PRK11594
1133852001696	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1133852001697	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852001698	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852001699	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1133852001700	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1133852001701	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1133852001702	RNAase interaction site [polypeptide binding]; other site
1133852001703	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852001704	arginine repressor; Provisional; Region: PRK05066
1133852001705	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1133852001706	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1133852001707	malate dehydrogenase; Provisional; Region: PRK05086
1133852001708	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1133852001709	NAD binding site [chemical binding]; other site
1133852001710	dimerization interface [polypeptide binding]; other site
1133852001711	Substrate binding site [chemical binding]; other site
1133852001712	serine endoprotease; Provisional; Region: PRK10898
1133852001713	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1133852001714	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133852001715	protein binding site [polypeptide binding]; other site
1133852001716	serine endoprotease; Provisional; Region: PRK10139
1133852001717	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1133852001718	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133852001719	protein binding site [polypeptide binding]; other site
1133852001720	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133852001721	hypothetical protein; Provisional; Region: PRK11677
1133852001722	Predicted ATPase [General function prediction only]; Region: COG1485
1133852001723	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1133852001724	23S rRNA interface [nucleotide binding]; other site
1133852001725	L3 interface [polypeptide binding]; other site
1133852001726	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1133852001727	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1133852001728	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1133852001729	C-terminal domain interface [polypeptide binding]; other site
1133852001730	putative GSH binding site (G-site) [chemical binding]; other site
1133852001731	dimer interface [polypeptide binding]; other site
1133852001732	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1133852001733	dimer interface [polypeptide binding]; other site
1133852001734	N-terminal domain interface [polypeptide binding]; other site
1133852001735	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1133852001736	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
1133852001737	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
1133852001738	transcriptional regulator NanR; Provisional; Region: PRK03837
1133852001739	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852001740	DNA-binding site [nucleotide binding]; DNA binding site
1133852001741	FCD domain; Region: FCD; pfam07729
1133852001742	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1133852001743	inhibitor site; inhibition site
1133852001744	active site
1133852001745	dimer interface [polypeptide binding]; other site
1133852001746	catalytic residue [active]
1133852001747	putative sialic acid transporter; Provisional; Region: PRK03893
1133852001748	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852001749	putative substrate translocation pore; other site
1133852001750	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1133852001751	putative active site cavity [active]
1133852001752	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133852001753	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852001754	nucleotide binding site [chemical binding]; other site
1133852001755	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
1133852001756	Protein of unknown function (DUF1016); Region: DUF1016; cl19557
1133852001757	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1133852001758	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
1133852001759	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852001760	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852001761	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1133852001762	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1133852001763	active site
1133852001764	dimer interface [polypeptide binding]; other site
1133852001765	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1133852001766	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1133852001767	active site
1133852001768	FMN binding site [chemical binding]; other site
1133852001769	substrate binding site [chemical binding]; other site
1133852001770	3Fe-4S cluster binding site [ion binding]; other site
1133852001771	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1133852001772	domain interface; other site
1133852001773	radical SAM protein, TIGR01212 family; Region: TIGR01212
1133852001774	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852001775	FeS/SAM binding site; other site
1133852001776	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1133852001777	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852001778	putative active site [active]
1133852001779	heme pocket [chemical binding]; other site
1133852001780	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852001781	dimer interface [polypeptide binding]; other site
1133852001782	phosphorylation site [posttranslational modification]
1133852001783	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852001784	ATP binding site [chemical binding]; other site
1133852001785	Mg2+ binding site [ion binding]; other site
1133852001786	G-X-G motif; other site
1133852001787	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852001788	active site
1133852001789	phosphorylation site [posttranslational modification]
1133852001790	intermolecular recognition site; other site
1133852001791	dimerization interface [polypeptide binding]; other site
1133852001792	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133852001793	putative binding surface; other site
1133852001794	active site
1133852001795	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1133852001796	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1133852001797	conserved cys residue [active]
1133852001798	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1133852001799	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1133852001800	hypothetical protein; Provisional; Region: PRK10345
1133852001801	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
1133852001802	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133852001803	dimerization domain swap beta strand [polypeptide binding]; other site
1133852001804	regulatory protein interface [polypeptide binding]; other site
1133852001805	active site
1133852001806	regulatory phosphorylation site [posttranslational modification]; other site
1133852001807	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1133852001808	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1133852001809	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852001810	active site
1133852001811	phosphorylation site [posttranslational modification]
1133852001812	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1133852001813	30S subunit binding site; other site
1133852001814	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1133852001815	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1133852001816	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1133852001817	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1133852001818	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1133852001819	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1133852001820	Walker A/P-loop; other site
1133852001821	ATP binding site [chemical binding]; other site
1133852001822	Q-loop/lid; other site
1133852001823	ABC transporter signature motif; other site
1133852001824	Walker B; other site
1133852001825	D-loop; other site
1133852001826	H-loop/switch region; other site
1133852001827	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1133852001828	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1133852001829	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1133852001830	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1133852001831	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1133852001832	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1133852001833	putative active site [active]
1133852001834	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1133852001835	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1133852001836	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1133852001837	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1133852001838	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1133852001839	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1133852001840	Walker A/P-loop; other site
1133852001841	ATP binding site [chemical binding]; other site
1133852001842	Q-loop/lid; other site
1133852001843	ABC transporter signature motif; other site
1133852001844	Walker B; other site
1133852001845	D-loop; other site
1133852001846	H-loop/switch region; other site
1133852001847	conserved hypothetical integral membrane protein; Region: TIGR00056
1133852001848	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1133852001849	mce related protein; Region: MCE; pfam02470
1133852001850	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1133852001851	Predicted NTP binding protein (contains STAS domain) [General function prediction only]; Region: COG3113
1133852001852	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1133852001853	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275
1133852001854	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1133852001855	hinge; other site
1133852001856	active site
1133852001857	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1133852001858	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1133852001859	substrate binding pocket [chemical binding]; other site
1133852001860	chain length determination region; other site
1133852001861	substrate-Mg2+ binding site; other site
1133852001862	catalytic residues [active]
1133852001863	aspartate-rich region 1; other site
1133852001864	active site lid residues [active]
1133852001865	aspartate-rich region 2; other site
1133852001866	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1133852001867	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1133852001868	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1133852001869	EamA-like transporter family; Region: EamA; pfam00892
1133852001870	EamA-like transporter family; Region: EamA; pfam00892
1133852001871	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1133852001872	GTP1/OBG; Region: GTP1_OBG; pfam01018
1133852001873	Obg GTPase; Region: Obg; cd01898
1133852001874	G1 box; other site
1133852001875	GTP/Mg2+ binding site [chemical binding]; other site
1133852001876	Switch I region; other site
1133852001877	G2 box; other site
1133852001878	G3 box; other site
1133852001879	Switch II region; other site
1133852001880	G4 box; other site
1133852001881	G5 box; other site
1133852001882	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1133852001883	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027
1133852001884	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1133852001885	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1133852001886	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1133852001887	RNA-binding protein YhbY; Provisional; Region: PRK10343
1133852001888	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852001889	S-adenosylmethionine binding site [chemical binding]; other site
1133852001890	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1133852001891	FtsH Extracellular; Region: FtsH_ext; pfam06480
1133852001892	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852001893	Walker A motif; other site
1133852001894	ATP binding site [chemical binding]; other site
1133852001895	Walker B motif; other site
1133852001896	arginine finger; other site
1133852001897	Peptidase family M41; Region: Peptidase_M41; pfam01434
1133852001898	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
1133852001899	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1133852001900	substrate binding pocket [chemical binding]; other site
1133852001901	dimer interface [polypeptide binding]; other site
1133852001902	inhibitor binding site; inhibition site
1133852001903	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1133852001904	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1133852001905	active site
1133852001906	substrate binding site [chemical binding]; other site
1133852001907	metal binding site [ion binding]; metal-binding site
1133852001908	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1133852001909	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1133852001910	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
1133852001911	Sulfatase; Region: Sulfatase; pfam00884
1133852001912	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1133852001913	ANP binding site [chemical binding]; other site
1133852001914	Substrate Binding Site II [chemical binding]; other site
1133852001915	Substrate Binding Site I [chemical binding]; other site
1133852001916	hypothetical protein; Provisional; Region: PRK14641
1133852001917	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1133852001918	putative oligomer interface [polypeptide binding]; other site
1133852001919	putative RNA binding site [nucleotide binding]; other site
1133852001920	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1133852001921	NusA N-terminal domain; Region: NusA_N; pfam08529
1133852001922	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1133852001923	RNA binding site [nucleotide binding]; other site
1133852001924	homodimer interface [polypeptide binding]; other site
1133852001925	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1133852001926	G-X-X-G motif; other site
1133852001927	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1133852001928	G-X-X-G motif; other site
1133852001929	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1133852001930	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1133852001931	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1133852001932	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1133852001933	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; cl01201
1133852001934	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1133852001935	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1133852001936	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1133852001937	G1 box; other site
1133852001938	putative GEF interaction site [polypeptide binding]; other site
1133852001939	GTP/Mg2+ binding site [chemical binding]; other site
1133852001940	Switch I region; other site
1133852001941	G2 box; other site
1133852001942	G3 box; other site
1133852001943	Switch II region; other site
1133852001944	G4 box; other site
1133852001945	G5 box; other site
1133852001946	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1133852001947	Translation-initiation factor 2; Region: IF-2; pfam11987
1133852001948	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1133852001949	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1133852001950	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1133852001951	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1133852001952	RNA binding site [nucleotide binding]; other site
1133852001953	active site
1133852001954	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1133852001955	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1133852001956	16S/18S rRNA binding site [nucleotide binding]; other site
1133852001957	S13e-L30e interaction site [polypeptide binding]; other site
1133852001958	25S rRNA binding site [nucleotide binding]; other site
1133852001959	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1133852001960	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1133852001961	RNase E interface [polypeptide binding]; other site
1133852001962	trimer interface [polypeptide binding]; other site
1133852001963	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1133852001964	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1133852001965	RNase E interface [polypeptide binding]; other site
1133852001966	trimer interface [polypeptide binding]; other site
1133852001967	active site
1133852001968	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1133852001969	putative nucleic acid binding region [nucleotide binding]; other site
1133852001970	G-X-X-G motif; other site
1133852001971	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1133852001972	RNA binding site [nucleotide binding]; other site
1133852001973	domain interface; other site
1133852001974	lipoprotein NlpI; Provisional; Region: PRK11189
1133852001975	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852001976	binding surface
1133852001977	TPR motif; other site
1133852001978	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
1133852001979	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133852001980	ATP binding site [chemical binding]; other site
1133852001981	Mg++ binding site [ion binding]; other site
1133852001982	motif III; other site
1133852001983	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852001984	nucleotide binding region [chemical binding]; other site
1133852001985	ATP-binding site [chemical binding]; other site
1133852001986	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1133852001987	putative RNA binding site [nucleotide binding]; other site
1133852001988	tryptophan permease; Provisional; Region: PRK10483
1133852001989	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852001990	hypothetical protein; Provisional; Region: PRK10508
1133852001991	putative protease; Provisional; Region: PRK15447
1133852001992	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1133852001993	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1133852001994	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1133852001995	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852001996	Coenzyme A binding pocket [chemical binding]; other site
1133852001997	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1133852001998	GIY-YIG motif/motif A; other site
1133852001999	putative active site [active]
1133852002000	putative metal binding site [ion binding]; other site
1133852002001	hypothetical protein; Provisional; Region: PRK03467
1133852002002	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1133852002003	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1133852002004	proposed catalytic triad [active]
1133852002005	conserved cys residue [active]
1133852002006	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133852002007	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1133852002008	NAD(P) binding site [chemical binding]; other site
1133852002009	active site
1133852002010	Predicted permease; Region: DUF318; pfam03773
1133852002011	outer membrane lipoprotein; Provisional; Region: PRK11023
1133852002012	BON domain; Region: BON; pfam04972
1133852002013	BON domain; Region: BON; pfam04972
1133852002014	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1133852002015	dimer interface [polypeptide binding]; other site
1133852002016	active site
1133852002017	TIGR00252 family protein; Region: TIGR00252
1133852002018	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1133852002019	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1133852002020	putative ligand binding site [chemical binding]; other site
1133852002021	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1133852002022	putative SAM binding site [chemical binding]; other site
1133852002023	putative homodimer interface [polypeptide binding]; other site
1133852002024	Fimbrial protein; Region: Fimbrial; pfam00419
1133852002025	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133852002026	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852002027	Outer membrane usher protein; Region: Usher; pfam00577
1133852002028	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852002029	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133852002030	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852002031	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852002032	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133852002033	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1133852002034	active site
1133852002035	trimer interface [polypeptide binding]; other site
1133852002036	allosteric site; other site
1133852002037	active site lid [active]
1133852002038	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
1133852002039	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
1133852002040	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1133852002041	active site
1133852002042	phosphorylation site [posttranslational modification]
1133852002043	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
1133852002044	active site
1133852002045	intersubunit interface [polypeptide binding]; other site
1133852002046	zinc binding site [ion binding]; other site
1133852002047	Na+ binding site [ion binding]; other site
1133852002048	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1133852002049	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1133852002050	dimer interface [polypeptide binding]; other site
1133852002051	active site
1133852002052	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1133852002053	putative active site [active]
1133852002054	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1133852002055	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1133852002056	active site
1133852002057	dimer interface [polypeptide binding]; other site
1133852002058	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1133852002059	active pocket/dimerization site; other site
1133852002060	active site
1133852002061	phosphorylation site [posttranslational modification]
1133852002062	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1133852002063	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1133852002064	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1133852002065	active site
1133852002066	phosphorylation site [posttranslational modification]
1133852002067	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
1133852002068	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
1133852002069	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852002070	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852002071	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
1133852002072	putative regulator PrlF; Provisional; Region: PRK09974
1133852002073	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1133852002074	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1133852002075	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1133852002076	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852002077	D-galactonate transporter; Region: 2A0114; TIGR00893
1133852002078	putative substrate translocation pore; other site
1133852002079	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1133852002080	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1133852002081	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
1133852002082	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
1133852002083	glycerate kinase I; Provisional; Region: PRK10342
1133852002084	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852002085	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852002086	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852002087	hypothetical protein; Provisional; Region: PRK09716
1133852002088	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
1133852002089	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1133852002090	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852002091	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1133852002092	putative substrate binding pocket [chemical binding]; other site
1133852002093	putative dimerization interface [polypeptide binding]; other site
1133852002094	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1133852002095	tetramer interface [polypeptide binding]; other site
1133852002096	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852002097	catalytic residue [active]
1133852002098	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1133852002099	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852002100	propionate/acetate kinase; Provisional; Region: PRK12379
1133852002101	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1133852002102	Pyruvate formate lyase 1; Region: PFL1; cd01678
1133852002103	coenzyme A binding site [chemical binding]; other site
1133852002104	active site
1133852002105	catalytic residues [active]
1133852002106	glycine loop; other site
1133852002107	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1133852002108	homotrimer interaction site [polypeptide binding]; other site
1133852002109	putative active site [active]
1133852002110	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1133852002111	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1133852002112	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1133852002113	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852002114	serine transporter; Region: stp; TIGR00814
1133852002115	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1133852002116	Pirin-related protein [General function prediction only]; Region: COG1741
1133852002117	Pirin; Region: Pirin; pfam02678
1133852002118	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852002119	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1133852002120	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852002121	dimerization interface [polypeptide binding]; other site
1133852002122	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852002123	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852002124	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852002125	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852002126	Predicted membrane protein [Function unknown]; Region: COG3152
1133852002127	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1133852002128	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1133852002129	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1133852002130	putative dimer interface [polypeptide binding]; other site
1133852002131	N-terminal domain interface [polypeptide binding]; other site
1133852002132	putative substrate binding pocket (H-site) [chemical binding]; other site
1133852002133	Predicted membrane protein [Function unknown]; Region: COG2259
1133852002134	YqjK-like protein; Region: YqjK; pfam13997
1133852002135	Predicted membrane protein [Function unknown]; Region: COG5393
1133852002136	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1133852002137	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1133852002138	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1133852002139	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133852002140	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1133852002141	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852002142	DNA-binding site [nucleotide binding]; DNA binding site
1133852002143	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852002144	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133852002145	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1133852002146	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
1133852002147	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1133852002148	Outer membrane usher protein; Region: Usher; pfam00577
1133852002149	CblD like pilus biogenesis initiator; Region: CblD; cl06460
1133852002150	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852002151	D-galactonate transporter; Region: 2A0114; TIGR00893
1133852002152	putative substrate translocation pore; other site
1133852002153	glucuronate isomerase; Reviewed; Region: PRK02925
1133852002154	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1133852002155	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1133852002156	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1133852002157	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
1133852002158	serine/threonine transporter SstT; Provisional; Region: PRK13628
1133852002159	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1133852002160	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1133852002161	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133852002162	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133852002163	putative active site [active]
1133852002164	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1133852002165	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1133852002166	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852002167	S-adenosylmethionine binding site [chemical binding]; other site
1133852002168	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
1133852002169	Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499
1133852002170	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852002171	non-specific DNA binding site [nucleotide binding]; other site
1133852002172	salt bridge; other site
1133852002173	sequence-specific DNA binding site [nucleotide binding]; other site
1133852002174	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
1133852002175	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1133852002176	active site
1133852002177	FMN binding site [chemical binding]; other site
1133852002178	2,4-decadienoyl-CoA binding site; other site
1133852002179	catalytic residue [active]
1133852002180	4Fe-4S cluster binding site [ion binding]; other site
1133852002181	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852002182	alpha-glucosidase; Provisional; Region: PRK10137
1133852002183	inner membrane transporter YjeM; Provisional; Region: PRK15238
1133852002184	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
1133852002185	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1133852002186	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1133852002187	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1133852002188	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1133852002189	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1133852002190	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1133852002191	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852002192	DNA binding site [nucleotide binding]
1133852002193	domain linker motif; other site
1133852002194	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1133852002195	putative dimerization interface [polypeptide binding]; other site
1133852002196	putative ligand binding site [chemical binding]; other site
1133852002197	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1133852002198	dimer interface [polypeptide binding]; other site
1133852002199	putative tRNA-binding site [nucleotide binding]; other site
1133852002200	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852002201	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1133852002202	inhibitor-cofactor binding pocket; inhibition site
1133852002203	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852002204	catalytic residue [active]
1133852002205	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852002206	PAS fold; Region: PAS_3; pfam08447
1133852002207	putative active site [active]
1133852002208	heme pocket [chemical binding]; other site
1133852002209	HAMP domain; Region: HAMP; pfam00672
1133852002210	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1133852002211	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133852002212	dimer interface [polypeptide binding]; other site
1133852002213	putative CheW interface [polypeptide binding]; other site
1133852002214	Predicted transcriptional regulators [Transcription]; Region: COG1695
1133852002215	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1133852002216	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1133852002217	FAD binding pocket [chemical binding]; other site
1133852002218	FAD binding motif [chemical binding]; other site
1133852002219	phosphate binding motif [ion binding]; other site
1133852002220	NAD binding pocket [chemical binding]; other site
1133852002221	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1133852002222	active site
1133852002223	SUMO-1 interface [polypeptide binding]; other site
1133852002224	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1133852002225	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1133852002226	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1133852002227	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1133852002228	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133852002229	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1133852002230	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133852002231	DNA binding residues [nucleotide binding]
1133852002232	DNA primase; Validated; Region: dnaG; PRK05667
1133852002233	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1133852002234	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1133852002235	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1133852002236	active site
1133852002237	metal binding site [ion binding]; metal-binding site
1133852002238	interdomain interaction site; other site
1133852002239	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1133852002240	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1133852002241	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1133852002242	UGMP family protein; Validated; Region: PRK09604
1133852002243	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852002244	nucleotide binding site [chemical binding]; other site
1133852002245	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
1133852002246	anion transporter; Region: dass; TIGR00785
1133852002247	transmembrane helices; other site
1133852002248	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1133852002249	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1133852002250	transcriptional activator TtdR; Provisional; Region: PRK09801
1133852002251	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852002252	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1133852002253	putative effector binding pocket; other site
1133852002254	putative dimerization interface [polypeptide binding]; other site
1133852002255	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1133852002256	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1133852002257	homooctamer interface [polypeptide binding]; other site
1133852002258	active site
1133852002259	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1133852002260	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1133852002261	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1133852002262	active site
1133852002263	NTP binding site [chemical binding]; other site
1133852002264	metal binding triad [ion binding]; metal-binding site
1133852002265	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1133852002266	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133852002267	Zn2+ binding site [ion binding]; other site
1133852002268	Mg2+ binding site [ion binding]; other site
1133852002269	SH3 domain-containing protein; Provisional; Region: PRK10884
1133852002270	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1133852002271	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1133852002272	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1133852002273	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1133852002274	putative active site [active]
1133852002275	putative metal binding residues [ion binding]; other site
1133852002276	signature motif; other site
1133852002277	putative triphosphate binding site [ion binding]; other site
1133852002278	CHAD domain; Region: CHAD; pfam05235
1133852002279	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1133852002280	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1133852002281	metal binding triad; other site
1133852002282	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1133852002283	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1133852002284	metal binding triad; other site
1133852002285	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; cl19627
1133852002286	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1133852002287	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1133852002288	putative ribose interaction site [chemical binding]; other site
1133852002289	putative ADP binding site [chemical binding]; other site
1133852002290	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1133852002291	active site
1133852002292	nucleotide binding site [chemical binding]; other site
1133852002293	HIGH motif; other site
1133852002294	KMSKS motif; other site
1133852002295	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1133852002296	Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_flotillin; cd03399
1133852002297	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1133852002298	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1133852002299	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1133852002300	Fimbrial protein; Region: Fimbrial; pfam00419
1133852002301	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133852002302	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852002303	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852002304	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133852002305	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852002306	Outer membrane usher protein; Region: Usher; pfam00577
1133852002307	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852002308	putative fimbrial protein; Provisional; Region: PRK09733
1133852002309	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1133852002310	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1133852002311	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1133852002312	zinc transporter ZupT; Provisional; Region: PRK04201
1133852002313	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1133852002314	putative active site [active]
1133852002315	metal binding site [ion binding]; metal-binding site
1133852002316	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1133852002317	hypothetical protein; Provisional; Region: PRK11653
1133852002318	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1133852002319	Outer membrane efflux protein; Region: OEP; pfam02321
1133852002320	Outer membrane efflux protein; Region: OEP; pfam02321
1133852002321	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1133852002322	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1133852002323	dimer interface [polypeptide binding]; other site
1133852002324	ADP-ribose binding site [chemical binding]; other site
1133852002325	active site
1133852002326	nudix motif; other site
1133852002327	metal binding site [ion binding]; metal-binding site
1133852002328	putative dehydrogenase; Provisional; Region: PRK11039
1133852002329	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1133852002330	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1133852002331	active site
1133852002332	metal binding site [ion binding]; metal-binding site
1133852002333	hexamer interface [polypeptide binding]; other site
1133852002334	esterase YqiA; Provisional; Region: PRK11071
1133852002335	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1133852002336	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1133852002337	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852002338	ATP binding site [chemical binding]; other site
1133852002339	Mg2+ binding site [ion binding]; other site
1133852002340	G-X-G motif; other site
1133852002341	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1133852002342	anchoring element; other site
1133852002343	dimer interface [polypeptide binding]; other site
1133852002344	ATP binding site [chemical binding]; other site
1133852002345	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1133852002346	active site
1133852002347	metal binding site [ion binding]; metal-binding site
1133852002348	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1133852002349	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1133852002350	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1133852002351	sensor protein QseC; Provisional; Region: PRK10337
1133852002352	HAMP domain; Region: HAMP; pfam00672
1133852002353	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852002354	dimer interface [polypeptide binding]; other site
1133852002355	phosphorylation site [posttranslational modification]
1133852002356	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852002357	ATP binding site [chemical binding]; other site
1133852002358	Mg2+ binding site [ion binding]; other site
1133852002359	G-X-G motif; other site
1133852002360	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1133852002361	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852002362	active site
1133852002363	phosphorylation site [posttranslational modification]
1133852002364	intermolecular recognition site; other site
1133852002365	dimerization interface [polypeptide binding]; other site
1133852002366	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852002367	DNA binding site [nucleotide binding]
1133852002368	TIGR00156 family protein; Region: TIGR00156
1133852002369	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1133852002370	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1133852002371	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1133852002372	CAP-like domain; other site
1133852002373	active site
1133852002374	primary dimer interface [polypeptide binding]; other site
1133852002375	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852002376	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1133852002377	putative acyl-acceptor binding pocket; other site
1133852002378	FtsI repressor; Provisional; Region: PRK10883
1133852002379	The first Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_1_CueO_FtsP; cd04232
1133852002380	Domain 2 interface [polypeptide binding]; other site
1133852002381	Domain 3 interface [polypeptide binding]; other site
1133852002382	trinuclear Cu binding site [ion binding]; other site
1133852002383	The second Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_2_CueO_FtsP; cd13867
1133852002384	Domain 1 interface [polypeptide binding]; other site
1133852002385	Domain 3 interface [polypeptide binding]; other site
1133852002386	The third Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_3_CueO_FtsP; cd13890
1133852002387	Domain 2 interface [polypeptide binding]; other site
1133852002388	Domain 1 interface [polypeptide binding]; other site
1133852002389	Type 1 (T1) Cu binding site [ion binding]; other site
1133852002390	trinuclear Cu binding site [ion binding]; other site
1133852002391	hypothetical protein; Provisional; Region: PRK01254
1133852002392	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1133852002393	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1133852002394	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1133852002395	putative outer membrane lipoprotein; Provisional; Region: PRK09973
1133852002396	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1133852002397	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852002398	active site
1133852002399	catalytic tetrad [active]
1133852002400	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1133852002401	dimer interface [polypeptide binding]; other site
1133852002402	active site
1133852002403	metal binding site [ion binding]; metal-binding site
1133852002404	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1133852002405	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133852002406	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852002407	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852002408	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133852002409	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1133852002410	homodimer interface [polypeptide binding]; other site
1133852002411	substrate-cofactor binding pocket; other site
1133852002412	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852002413	catalytic residue [active]
1133852002414	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1133852002415	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1133852002416	oxidoreductase; Provisional; Region: PRK07985
1133852002417	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1133852002418	NAD binding site [chemical binding]; other site
1133852002419	metal binding site [ion binding]; metal-binding site
1133852002420	active site
1133852002421	hypothetical protein; Provisional; Region: PRK05208
1133852002422	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852002423	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852002424	active site
1133852002425	catalytic tetrad [active]
1133852002426	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1133852002427	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
1133852002428	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1133852002429	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1133852002430	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133852002431	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1133852002432	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
1133852002433	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1133852002434	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852002435	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1133852002436	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1133852002437	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1133852002438	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1133852002439	putative substrate-binding site; other site
1133852002440	nickel binding site [ion binding]; other site
1133852002441	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1133852002442	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1133852002443	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1133852002444	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852002445	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852002446	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852002447	putative S-transferase; Provisional; Region: PRK11752
1133852002448	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1133852002449	C-terminal domain interface [polypeptide binding]; other site
1133852002450	GSH binding site (G-site) [chemical binding]; other site
1133852002451	dimer interface [polypeptide binding]; other site
1133852002452	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1133852002453	dimer interface [polypeptide binding]; other site
1133852002454	N-terminal domain interface [polypeptide binding]; other site
1133852002455	active site
1133852002456	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1133852002457	CHAP domain; Region: CHAP; pfam05257
1133852002458	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1133852002459	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1133852002460	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1133852002461	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1133852002462	TMP-binding site; other site
1133852002463	ATP-binding site [chemical binding]; other site
1133852002464	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1133852002465	TMP-binding site; other site
1133852002466	ATP-binding site [chemical binding]; other site
1133852002467	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1133852002468	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1133852002469	active site
1133852002470	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1133852002471	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1133852002472	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
1133852002473	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1133852002474	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1133852002475	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
1133852002476	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1133852002477	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852002478	catalytic residue [active]
1133852002479	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133852002480	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133852002481	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133852002482	NAD(P) binding site [chemical binding]; other site
1133852002483	active site
1133852002484	acyl-CoA synthetase; Validated; Region: PRK09192
1133852002485	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
1133852002486	acyl-activating enzyme (AAE) consensus motif; other site
1133852002487	active site
1133852002488	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
1133852002489	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852002490	DNA-binding site [nucleotide binding]; DNA binding site
1133852002491	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852002492	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
1133852002493	FAD binding domain; Region: FAD_binding_4; pfam01565
1133852002494	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
1133852002495	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
1133852002496	FAD binding domain; Region: FAD_binding_4; pfam01565
1133852002497	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
1133852002498	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1133852002499	Cysteine-rich domain; Region: CCG; pfam02754
1133852002500	Cysteine-rich domain; Region: CCG; pfam02754
1133852002501	hypothetical protein; Provisional; Region: PRK09732
1133852002502	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
1133852002503	active site
1133852002504	glycolate transporter; Provisional; Region: PRK09695
1133852002505	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
1133852002506	Peptidase M60-like family; Region: M60-like; pfam13402
1133852002507	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1133852002508	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1133852002509	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1133852002510	putative type II secretion protein GspC; Provisional; Region: PRK09681
1133852002511	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1133852002512	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1133852002513	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1133852002514	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133852002515	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133852002516	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1133852002517	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1133852002518	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1133852002519	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1133852002520	Walker A motif; other site
1133852002521	ATP binding site [chemical binding]; other site
1133852002522	Walker B motif; other site
1133852002523	type II secretion system protein F; Region: GspF; TIGR02120
1133852002524	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133852002525	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133852002526	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1133852002527	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1133852002528	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1133852002529	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
1133852002530	Type II transport protein GspH; Region: GspH; pfam12019
1133852002531	type II secretion system protein I; Region: gspI; TIGR01707
1133852002532	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1133852002533	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1133852002534	type II secretion system protein J; Region: gspJ; TIGR01711
1133852002535	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1133852002536	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1133852002537	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl19066
1133852002538	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
1133852002539	GspL-like protein; Provisional; Region: PRK09662
1133852002540	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
1133852002541	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133852002542	Herpes virus major capsid protein; Region: Herpes_MCP; pfam03122
1133852002543	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133852002544	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133852002545	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133852002546	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133852002547	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133852002548	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133852002549	MPN+ (JAMM) motif; other site
1133852002550	Zinc-binding site [ion binding]; other site
1133852002551	Antirestriction protein; Region: Antirestrict; pfam03230
1133852002552	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133852002553	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1133852002554	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852002555	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133852002556	hypothetical protein; Provisional; Region: PRK09945
1133852002557	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133852002558	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852002559	Autotransporter beta-domain; Region: Autotransporter; smart00869
1133852002560	Predicted GTPase [General function prediction only]; Region: COG3596
1133852002561	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852002562	YfjP GTPase; Region: YfjP; cd11383
1133852002563	G1 box; other site
1133852002564	GTP/Mg2+ binding site [chemical binding]; other site
1133852002565	Switch I region; other site
1133852002566	G2 box; other site
1133852002567	Switch II region; other site
1133852002568	G3 box; other site
1133852002569	G4 box; other site
1133852002570	G5 box; other site
1133852002571	Replication regulatory protein RepB; Region: RepB-RCR_reg; cl11673
1133852002572	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1133852002573	Haemolysin expression modulating protein; Region: HHA; pfam05321
1133852002574	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133852002575	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852002576	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852002577	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133852002578	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1133852002579	Protein of unknown function (DUF877); Region: DUF877; cl05484
1133852002580	T5orf172 domain; Region: T5orf172; pfam10544
1133852002581	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
1133852002582	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1133852002583	PerC transcriptional activator; Region: PerC; pfam06069
1133852002584	Integrase core domain; Region: rve; pfam00665
1133852002585	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1133852002586	Protein of unknown function (DUF877); Region: DUF877; cl05484
1133852002587	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1133852002588	Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462
1133852002589	Protein of unknown function (DUF1305); Region: DUF1305; cl01404
1133852002590	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133852002591	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133852002592	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133852002593	PAAR motif; Region: PAAR_motif; pfam05488
1133852002594	ImpA-related N-terminal; Region: ImpA-rel_N; cl19907
1133852002595	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1133852002596	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1133852002597	Bacterial protein of unknown function (DUF876); Region: DUF876; cl01406
1133852002598	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; cl01370
1133852002599	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
1133852002600	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1133852002601	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852002602	Walker A motif; other site
1133852002603	ATP binding site [chemical binding]; other site
1133852002604	Walker B motif; other site
1133852002605	arginine finger; other site
1133852002606	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852002607	Walker A motif; other site
1133852002608	ATP binding site [chemical binding]; other site
1133852002609	Walker B motif; other site
1133852002610	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133852002611	potential frameshift: common BLAST hit: gi|218698137|ref|YP_002405804.1| reverse transcriptase-like protein from prophage or plasmid
1133852002612	Integrase core domain; Region: rve; pfam00665
1133852002613	Integrase core domain; Region: rve_3; cl15866
1133852002614	ImpA-related N-terminal; Region: ImpA-rel_N; cl19907
1133852002615	ImpA domain protein; Region: DUF3702; pfam12486
1133852002616	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852002617	potential frameshift: common BLAST hit: gi|218697858|ref|YP_002405525.1| transposase, IS110 family
1133852002618	Integrase core domain; Region: rve; pfam00665
1133852002619	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852002620	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852002621	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1133852002622	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133852002623	DNA-binding interface [nucleotide binding]; DNA binding site
1133852002624	Integrase core domain; Region: rve; pfam00665
1133852002625	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852002626	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1133852002627	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1133852002628	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852002629	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1133852002630	Transposase, Mutator family; Region: Transposase_mut; cl19537
1133852002631	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852002632	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133852002633	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133852002634	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852002635	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852002636	Integrase core domain; Region: rve; pfam00665
1133852002637	Integrase core domain; Region: rve_3; cl15866
1133852002638	potential frameshift: common BLAST hit: gi|218698137|ref|YP_002405804.1| reverse transcriptase-like protein from prophage or plasmid
1133852002639	putative transposase OrfB; Reviewed; Region: PHA02517
1133852002640	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1133852002641	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133852002642	Homeodomain-like domain; Region: HTH_32; pfam13565
1133852002643	Integrase core domain; Region: rve; pfam00665
1133852002644	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852002645	Transposase; Region: HTH_Tnp_1; cl17663
1133852002646	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1133852002647	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133852002648	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1133852002649	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133852002650	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
1133852002651	Subtilase family; Region: Peptidase_S8; pfam00082
1133852002652	active site
1133852002653	catalytic triad [active]
1133852002654	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1133852002655	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852002656	Walker A motif; other site
1133852002657	ATP binding site [chemical binding]; other site
1133852002658	Walker B motif; other site
1133852002659	arginine finger; other site
1133852002660	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1133852002661	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852002662	ATP binding site [chemical binding]; other site
1133852002663	putative Mg++ binding site [ion binding]; other site
1133852002664	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1133852002665	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852002666	nucleotide binding region [chemical binding]; other site
1133852002667	ATP-binding site [chemical binding]; other site
1133852002668	SNF-7-like protein; Provisional; Region: PTZ00464
1133852002669	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
1133852002670	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852002671	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852002672	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852002673	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852002674	integrase; Provisional; Region: PRK09692
1133852002675	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852002676	active site
1133852002677	Int/Topo IB signature motif; other site
1133852002678	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1133852002679	ornithine decarboxylase; Provisional; Region: PRK13578
1133852002680	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133852002681	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133852002682	homodimer interface [polypeptide binding]; other site
1133852002683	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852002684	catalytic residue [active]
1133852002685	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133852002686	nucleoside transporter; Region: 2A0110; TIGR00889
1133852002687	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1133852002688	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1133852002689	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1133852002690	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852002691	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852002692	catalytic residue [active]
1133852002693	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2924
1133852002694	adenine DNA glycosylase; Provisional; Region: PRK10880
1133852002695	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1133852002696	minor groove reading motif; other site
1133852002697	helix-hairpin-helix signature motif; other site
1133852002698	substrate binding pocket [chemical binding]; other site
1133852002699	active site
1133852002700	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1133852002701	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1133852002702	DNA binding and oxoG recognition site [nucleotide binding]
1133852002703	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
1133852002704	hypothetical protein; Provisional; Region: PRK11702
1133852002705	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852002706	hypothetical protein; Provisional; Region: PRK10626
1133852002707	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1133852002708	active site
1133852002709	homodimer interface [polypeptide binding]; other site
1133852002710	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1133852002711	HemN family oxidoreductase; Provisional; Region: PRK05660
1133852002712	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852002713	FeS/SAM binding site; other site
1133852002714	HemN C-terminal domain; Region: HemN_C; pfam06969
1133852002715	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1133852002716	active site
1133852002717	dimerization interface [polypeptide binding]; other site
1133852002718	hypothetical protein; Validated; Region: PRK05090
1133852002719	YGGT family; Region: YGGT; pfam02325
1133852002720	Predicted integral membrane protein [Function unknown]; Region: COG0762
1133852002721	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1133852002722	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133852002723	catalytic residue [active]
1133852002724	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1133852002725	Walker A motif; other site
1133852002726	ATP binding site [chemical binding]; other site
1133852002727	Walker B motif; other site
1133852002728	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1133852002729	hypothetical protein; Validated; Region: PRK00228
1133852002730	glutathione synthetase; Provisional; Region: PRK05246
1133852002731	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1133852002732	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1133852002733	RNA methyltransferase, RsmE family; Region: TIGR00046
1133852002734	DNA-specific endonuclease I; Provisional; Region: PRK15137
1133852002735	hypothetical protein; Provisional; Region: PRK04860
1133852002736	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1133852002737	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852002738	putative substrate translocation pore; other site
1133852002739	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1133852002740	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1133852002741	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1133852002742	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1133852002743	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
1133852002744	Virulence promoting factor; Region: YqgB; pfam11036
1133852002745	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1133852002746	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1133852002747	dimer interface [polypeptide binding]; other site
1133852002748	active site
1133852002749	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133852002750	catalytic residues [active]
1133852002751	substrate binding site [chemical binding]; other site
1133852002752	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1133852002753	oligomer interface [polypeptide binding]; other site
1133852002754	putative active site [active]
1133852002755	Mn binding site [ion binding]; other site
1133852002756	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1133852002757	transketolase; Reviewed; Region: PRK12753
1133852002758	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1133852002759	TPP-binding site [chemical binding]; other site
1133852002760	dimer interface [polypeptide binding]; other site
1133852002761	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1133852002762	PYR/PP interface [polypeptide binding]; other site
1133852002763	dimer interface [polypeptide binding]; other site
1133852002764	TPP binding site [chemical binding]; other site
1133852002765	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1133852002766	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852002767	active site
1133852002768	phosphorylation site [posttranslational modification]
1133852002769	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1133852002770	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1133852002771	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1133852002772	active site
1133852002773	P-loop; other site
1133852002774	phosphorylation site [posttranslational modification]
1133852002775	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
1133852002776	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852002777	putative NAD(P) binding site [chemical binding]; other site
1133852002778	catalytic Zn binding site [ion binding]; other site
1133852002779	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1133852002780	putative active site [active]
1133852002781	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
1133852002782	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
1133852002783	active site
1133852002784	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1133852002785	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1133852002786	Walker A/P-loop; other site
1133852002787	ATP binding site [chemical binding]; other site
1133852002788	Q-loop/lid; other site
1133852002789	ABC transporter signature motif; other site
1133852002790	Walker B; other site
1133852002791	D-loop; other site
1133852002792	H-loop/switch region; other site
1133852002793	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1133852002794	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1133852002795	Walker A/P-loop; other site
1133852002796	ATP binding site [chemical binding]; other site
1133852002797	Q-loop/lid; other site
1133852002798	ABC transporter signature motif; other site
1133852002799	Walker B; other site
1133852002800	D-loop; other site
1133852002801	H-loop/switch region; other site
1133852002802	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1133852002803	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1133852002804	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1133852002805	trimer interface [polypeptide binding]; other site
1133852002806	putative Zn binding site [ion binding]; other site
1133852002807	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1133852002808	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1133852002809	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1133852002810	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1133852002811	substrate binding site [chemical binding]; other site
1133852002812	hinge regions; other site
1133852002813	ADP binding site [chemical binding]; other site
1133852002814	catalytic site [active]
1133852002815	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1133852002816	active site
1133852002817	intersubunit interface [polypeptide binding]; other site
1133852002818	zinc binding site [ion binding]; other site
1133852002819	Na+ binding site [ion binding]; other site
1133852002820	mechanosensitive channel MscS; Provisional; Region: PRK10334
1133852002821	Conserved TM helix; Region: TM_helix; pfam05552
1133852002822	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133852002823	arginine exporter protein; Provisional; Region: PRK09304
1133852002824	oxidative stress defense protein; Provisional; Region: PRK11087
1133852002825	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852002826	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852002827	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133852002828	dimerization interface [polypeptide binding]; other site
1133852002829	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1133852002830	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
1133852002831	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1133852002832	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
1133852002833	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852002834	substrate binding site [chemical binding]; other site
1133852002835	oxyanion hole (OAH) forming residues; other site
1133852002836	trimer interface [polypeptide binding]; other site
1133852002837	LAO/AO transport system ATPase; Region: lao; TIGR00750
1133852002838	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1133852002839	Walker A; other site
1133852002840	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
1133852002841	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1133852002842	B12 binding site [chemical binding]; other site
1133852002843	cobalt ligand [ion binding]; other site
1133852002844	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
1133852002845	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1133852002846	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852002847	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1133852002848	putative dimerization interface [polypeptide binding]; other site
1133852002849	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1133852002850	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133852002851	active site
1133852002852	dimer interface [polypeptide binding]; other site
1133852002853	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1133852002854	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1133852002855	ligand binding site [chemical binding]; other site
1133852002856	NAD binding site [chemical binding]; other site
1133852002857	tetramer interface [polypeptide binding]; other site
1133852002858	catalytic site [active]
1133852002859	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1133852002860	L-serine binding site [chemical binding]; other site
1133852002861	ACT domain interface; other site
1133852002862	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1133852002863	Z-ring-associated protein; Provisional; Region: PRK10972
1133852002864	hypothetical protein; Reviewed; Region: PRK01736
1133852002865	proline aminopeptidase P II; Provisional; Region: PRK10879
1133852002866	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1133852002867	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1133852002868	active site
1133852002869	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1133852002870	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1133852002871	oxidoreductase; Provisional; Region: PRK08013
1133852002872	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1133852002873	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1133852002874	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
1133852002875	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1133852002876	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1133852002877	lipoyl attachment site [posttranslational modification]; other site
1133852002878	glycine dehydrogenase; Provisional; Region: PRK05367
1133852002879	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1133852002880	tetramer interface [polypeptide binding]; other site
1133852002881	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852002882	catalytic residue [active]
1133852002883	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1133852002884	tetramer interface [polypeptide binding]; other site
1133852002885	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852002886	catalytic residue [active]
1133852002887	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1133852002888	classical (c) SDRs; Region: SDR_c; cd05233
1133852002889	NAD(P) binding site [chemical binding]; other site
1133852002890	active site
1133852002891	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1133852002892	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
1133852002893	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1133852002894	hemolysin; Provisional; Region: PRK15087
1133852002895	putative global regulator; Reviewed; Region: PRK09559
1133852002896	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
1133852002897	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1133852002898	hypothetical protein; Provisional; Region: PRK10878
1133852002899	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1133852002900	flavodoxin FldB; Provisional; Region: PRK12359
1133852002901	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1133852002902	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1133852002903	active site
1133852002904	Int/Topo IB signature motif; other site
1133852002905	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1133852002906	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1133852002907	dimerization domain [polypeptide binding]; other site
1133852002908	dimer interface [polypeptide binding]; other site
1133852002909	catalytic residues [active]
1133852002910	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1133852002911	DHH family; Region: DHH; pfam01368
1133852002912	DHHA1 domain; Region: DHHA1; pfam02272
1133852002913	peptide chain release factor 2; Provisional; Region: PRK08787
1133852002914	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1133852002915	RF-1 domain; Region: RF-1; pfam00472
1133852002916	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1133852002917	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1133852002918	dimer interface [polypeptide binding]; other site
1133852002919	putative anticodon binding site; other site
1133852002920	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1133852002921	motif 1; other site
1133852002922	active site
1133852002923	motif 2; other site
1133852002924	motif 3; other site
1133852002925	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1133852002926	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1133852002927	active site
1133852002928	metal binding site [ion binding]; metal-binding site
1133852002929	nudix motif; other site
1133852002930	Sulfate transporter family; Region: Sulfate_transp; cl19250
1133852002931	xanthine permease; Region: pbuX; TIGR03173
1133852002932	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
1133852002933	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852002934	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
1133852002935	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126
1133852002936	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1133852002937	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852002938	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133852002939	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852002940	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133852002941	Sulfate transporter family; Region: Sulfate_transp; cl19250
1133852002942	guanine deaminase; Provisional; Region: PRK09228
1133852002943	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1133852002944	active site
1133852002945	uracil-xanthine permease; Region: ncs2; TIGR00801
1133852002946	Sulfate transporter family; Region: Sulfate_transp; cl19250
1133852002947	probable selenate reductase, molybdenum-binding subunit; Region: Se_sel_red_Mo; TIGR03313
1133852002948	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1133852002949	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1133852002950	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1133852002951	FAD binding domain; Region: FAD_binding_4; cl19922
1133852002952	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
1133852002953	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1133852002954	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
1133852002955	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1133852002956	active site
1133852002957	putative substrate binding pocket [chemical binding]; other site
1133852002958	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
1133852002959	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1133852002960	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852002961	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1133852002962	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1133852002963	Ligand binding site; other site
1133852002964	metal-binding site
1133852002965	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1133852002966	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
1133852002967	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1133852002968	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1133852002969	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1133852002970	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
1133852002971	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1133852002972	putative substrate binding site [chemical binding]; other site
1133852002973	nucleotide binding site [chemical binding]; other site
1133852002974	nucleotide binding site [chemical binding]; other site
1133852002975	homodimer interface [polypeptide binding]; other site
1133852002976	D-hydantoinase; Region: D-hydantoinase; TIGR02033
1133852002977	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1133852002978	tetramer interface [polypeptide binding]; other site
1133852002979	active site
1133852002980	peptidase; Reviewed; Region: PRK13004
1133852002981	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
1133852002982	putative metal binding site [ion binding]; other site
1133852002983	putative dimer interface [polypeptide binding]; other site
1133852002984	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1133852002985	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852002986	catalytic residue [active]
1133852002987	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
1133852002988	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1133852002989	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1133852002990	GAF domain; Region: GAF; cl17456
1133852002991	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1133852002992	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852002993	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852002994	Walker A motif; other site
1133852002995	ATP binding site [chemical binding]; other site
1133852002996	Walker B motif; other site
1133852002997	arginine finger; other site
1133852002998	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133852002999	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
1133852003000	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852003001	catalytic loop [active]
1133852003002	iron binding site [ion binding]; other site
1133852003003	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1133852003004	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
1133852003005	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
1133852003006	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1133852003007	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
1133852003008	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1133852003009	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1133852003010	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1133852003011	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852003012	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133852003013	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1133852003014	potential frameshift: common BLAST hit: gi|170018890|ref|YP_001723844.1| surface presentation of antigens protein SpaO
1133852003015	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1133852003016	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1133852003017	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
1133852003018	potential frameshift: common BLAST hit: gi|218706359|ref|YP_002413878.1| surface presentation of antigens protein SpaS
1133852003019	FlhB HrpN YscU SpaS Family; Region: Bac_export_2; cl19167
1133852003020	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1133852003021	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852003022	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1133852003023	DNA binding residues [nucleotide binding]
1133852003024	dimerization interface [polypeptide binding]; other site
1133852003025	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1133852003026	Type III secretion needle MxiH like; Region: MxiH; cl09641
1133852003027	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1133852003028	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
1133852003029	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; pfam09482
1133852003030	invasion protein OrgB; Provisional; Region: PRK15322
1133852003031	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852003032	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852003033	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852003034	DNA binding residues [nucleotide binding]
1133852003035	dimerization interface [polypeptide binding]; other site
1133852003036	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1133852003037	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852003038	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852003039	catalytic residue [active]
1133852003040	transcriptional regulator; Provisional; Region: PRK11906
1133852003041	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1133852003042	DNA binding site [nucleotide binding]
1133852003043	Tetratricopeptide repeat; Region: TPR_2; pfam07719
1133852003044	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
1133852003045	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1133852003046	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1133852003047	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
1133852003048	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1133852003049	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1133852003050	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852003051	serine transporter; Region: stp; TIGR00814
1133852003052	putative acyltransferase; Provisional; Region: PRK05790
1133852003053	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133852003054	dimer interface [polypeptide binding]; other site
1133852003055	active site
1133852003056	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1133852003057	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1133852003058	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1133852003059	NADP binding site [chemical binding]; other site
1133852003060	homodimer interface [polypeptide binding]; other site
1133852003061	active site
1133852003062	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1133852003063	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003064	putative substrate translocation pore; other site
1133852003065	putative racemase; Provisional; Region: PRK10200
1133852003066	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1133852003067	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852003068	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
1133852003069	putative dimerization interface [polypeptide binding]; other site
1133852003070	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1133852003071	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1133852003072	active site
1133852003073	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133852003074	substrate binding site [chemical binding]; other site
1133852003075	catalytic residues [active]
1133852003076	dimer interface [polypeptide binding]; other site
1133852003077	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1133852003078	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852003079	DNA binding site [nucleotide binding]
1133852003080	domain linker motif; other site
1133852003081	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1133852003082	dimerization interface (closed form) [polypeptide binding]; other site
1133852003083	ligand binding site [chemical binding]; other site
1133852003084	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1133852003085	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1133852003086	putative acyl-acceptor binding pocket; other site
1133852003087	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1133852003088	acyl-activating enzyme (AAE) consensus motif; other site
1133852003089	putative AMP binding site [chemical binding]; other site
1133852003090	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003091	putative substrate translocation pore; other site
1133852003092	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852003093	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852003094	active site
1133852003095	catalytic tetrad [active]
1133852003096	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1133852003097	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1133852003098	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1133852003099	putative DNA-binding cleft [nucleotide binding]; other site
1133852003100	putative DNA clevage site; other site
1133852003101	molecular lever; other site
1133852003102	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1133852003103	putative active site [active]
1133852003104	Ap4A binding site [chemical binding]; other site
1133852003105	nudix motif; other site
1133852003106	putative metal binding site [ion binding]; other site
1133852003107	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1133852003108	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133852003109	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
1133852003110	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133852003111	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133852003112	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1133852003113	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1133852003114	dimerization interface [polypeptide binding]; other site
1133852003115	active site
1133852003116	hypothetical protein; Provisional; Region: PRK10506
1133852003117	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1133852003118	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1133852003119	hypothetical protein; Provisional; Region: PRK10557
1133852003120	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1133852003121	hypothetical protein; Provisional; Region: PRK11521
1133852003122	hypothetical protein; Provisional; Region: PRK10332
1133852003123	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1133852003124	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
1133852003125	protease3; Provisional; Region: PRK15101
1133852003126	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1133852003127	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133852003128	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133852003129	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1133852003130	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1133852003131	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1133852003132	Helicase; Region: Helicase_RecD; pfam05127
1133852003133	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1133852003134	N-acetylglutamate synthase; Validated; Region: PRK05279
1133852003135	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1133852003136	putative feedback inhibition sensing region; other site
1133852003137	putative nucleotide binding site [chemical binding]; other site
1133852003138	putative substrate binding site [chemical binding]; other site
1133852003139	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852003140	Coenzyme A binding pocket [chemical binding]; other site
1133852003141	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1133852003142	AMIN domain; Region: AMIN; pfam11741
1133852003143	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1133852003144	active site
1133852003145	metal binding site [ion binding]; metal-binding site
1133852003146	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1133852003147	MltA specific insert domain; Region: MltA; smart00925
1133852003148	3D domain; Region: 3D; pfam06725
1133852003149	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1133852003150	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1133852003151	putative ATP binding site [chemical binding]; other site
1133852003152	putative substrate interface [chemical binding]; other site
1133852003153	CsdA-binding activator; Provisional; Region: PRK15019
1133852003154	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1133852003155	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
1133852003156	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852003157	catalytic residue [active]
1133852003158	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1133852003159	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1133852003160	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852003161	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1133852003162	dimerization interface [polypeptide binding]; other site
1133852003163	substrate binding pocket [chemical binding]; other site
1133852003164	hypothetical protein; Provisional; Region: PRK10873
1133852003165	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1133852003166	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1133852003167	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1133852003168	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852003169	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852003170	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1133852003171	L-fuculokinase; Provisional; Region: PRK10331
1133852003172	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1133852003173	nucleotide binding site [chemical binding]; other site
1133852003174	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1133852003175	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1133852003176	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1133852003177	trimer interface [polypeptide binding]; other site
1133852003178	substrate binding site [chemical binding]; other site
1133852003179	Mn binding site [ion binding]; other site
1133852003180	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1133852003181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003182	putative substrate translocation pore; other site
1133852003183	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133852003184	intersubunit interface [polypeptide binding]; other site
1133852003185	active site
1133852003186	Zn2+ binding site [ion binding]; other site
1133852003187	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1133852003188	dimer interface [polypeptide binding]; other site
1133852003189	active site
1133852003190	metal binding site [ion binding]; metal-binding site
1133852003191	flap endonuclease-like protein; Provisional; Region: PRK09482
1133852003192	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1133852003193	active site
1133852003194	metal binding site 1 [ion binding]; metal-binding site
1133852003195	putative 5' ssDNA interaction site; other site
1133852003196	metal binding site 3; metal-binding site
1133852003197	metal binding site 2 [ion binding]; metal-binding site
1133852003198	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1133852003199	putative DNA binding site [nucleotide binding]; other site
1133852003200	putative metal binding site [ion binding]; other site
1133852003201	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1133852003202	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1133852003203	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1133852003204	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852003205	serine transporter; Region: stp; TIGR00814
1133852003206	Domain of unknown function (DUF4478); Region: DUF4478; pfam14793
1133852003207	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1133852003208	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1133852003209	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1133852003210	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1133852003211	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1133852003212	SecY interacting protein Syd; Provisional; Region: PRK04968
1133852003213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1133852003214	potential frameshift: common BLAST hit: gi|260869469|ref|YP_003235871.1| tRNA pseudouridine synthase
1133852003215	flavodoxin; Provisional; Region: PRK08105
1133852003216	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003217	D-galactonate transporter; Region: 2A0114; TIGR00893
1133852003218	putative substrate translocation pore; other site
1133852003219	potential frameshift: common BLAST hit: gi|260845434|ref|YP_003223212.1| (D)-glucarate dehydratase 2 GudX
1133852003220	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1133852003221	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1133852003222	active site
1133852003223	tetramer interface [polypeptide binding]; other site
1133852003224	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1133852003225	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1133852003226	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852003227	dimerization interface [polypeptide binding]; other site
1133852003228	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852003229	dimer interface [polypeptide binding]; other site
1133852003230	phosphorylation site [posttranslational modification]
1133852003231	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852003232	ATP binding site [chemical binding]; other site
1133852003233	Mg2+ binding site [ion binding]; other site
1133852003234	G-X-G motif; other site
1133852003235	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1133852003236	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852003237	active site
1133852003238	phosphorylation site [posttranslational modification]
1133852003239	intermolecular recognition site; other site
1133852003240	dimerization interface [polypeptide binding]; other site
1133852003241	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133852003242	putative binding surface; other site
1133852003243	active site
1133852003244	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1133852003245	TRAM domain; Region: TRAM; pfam01938
1133852003246	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852003247	S-adenosylmethionine binding site [chemical binding]; other site
1133852003248	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1133852003249	HD domain; Region: HD_4; pfam13328
1133852003250	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1133852003251	synthetase active site [active]
1133852003252	NTP binding site [chemical binding]; other site
1133852003253	metal binding site [ion binding]; metal-binding site
1133852003254	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1133852003255	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1133852003256	antitoxin MazE; Provisional; Region: PRK09798
1133852003257	toxin MazF; Provisional; Region: PRK09907
1133852003258	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1133852003259	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1133852003260	homodimer interface [polypeptide binding]; other site
1133852003261	metal binding site [ion binding]; metal-binding site
1133852003262	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1133852003263	homodimer interface [polypeptide binding]; other site
1133852003264	active site
1133852003265	putative chemical substrate binding site [chemical binding]; other site
1133852003266	metal binding site [ion binding]; metal-binding site
1133852003267	CTP synthetase; Validated; Region: pyrG; PRK05380
1133852003268	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1133852003269	Catalytic site [active]
1133852003270	active site
1133852003271	UTP binding site [chemical binding]; other site
1133852003272	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1133852003273	active site
1133852003274	putative oxyanion hole; other site
1133852003275	catalytic triad [active]
1133852003276	enolase; Provisional; Region: eno; PRK00077
1133852003277	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1133852003278	dimer interface [polypeptide binding]; other site
1133852003279	metal binding site [ion binding]; metal-binding site
1133852003280	substrate binding pocket [chemical binding]; other site
1133852003281	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1133852003282	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1133852003283	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1133852003284	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1133852003285	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1133852003286	nucleotide binding site [chemical binding]; other site
1133852003287	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852003288	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003289	putative substrate translocation pore; other site
1133852003290	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
1133852003291	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1133852003292	NADP binding site [chemical binding]; other site
1133852003293	homodimer interface [polypeptide binding]; other site
1133852003294	active site
1133852003295	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1133852003296	FAD binding domain; Region: FAD_binding_4; pfam01565
1133852003297	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
1133852003298	benzoate transport; Region: 2A0115; TIGR00895
1133852003299	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003300	putative substrate translocation pore; other site
1133852003301	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1133852003302	Ligand binding site [chemical binding]; other site
1133852003303	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1133852003304	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1133852003305	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1133852003306	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1133852003307	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
1133852003308	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1133852003309	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852003310	putative oxidoreductase FixC; Provisional; Region: PRK10157
1133852003311	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
1133852003312	homohexamer interface [polypeptide binding]; other site
1133852003313	putative substrate stabilizing pore; other site
1133852003314	pterin binding site; other site
1133852003315	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1133852003316	Flavodoxin; Region: Flavodoxin_1; pfam00258
1133852003317	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1133852003318	FAD binding pocket [chemical binding]; other site
1133852003319	FAD binding motif [chemical binding]; other site
1133852003320	catalytic residues [active]
1133852003321	NAD binding pocket [chemical binding]; other site
1133852003322	phosphate binding motif [ion binding]; other site
1133852003323	beta-alpha-beta structure motif; other site
1133852003324	sulfite reductase subunit beta; Provisional; Region: PRK13504
1133852003325	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1133852003326	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
1133852003327	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1133852003328	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852003329	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1133852003330	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133852003331	Active Sites [active]
1133852003332	Hok/gef family; Region: HOK_GEF; pfam01848
1133852003333	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133852003334	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852003335	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1133852003336	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1133852003337	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
1133852003338	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1133852003339	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
1133852003340	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1133852003341	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1133852003342	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
1133852003343	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1133852003344	putative ssRNA endonuclease; Provisional; Region: PRK11558
1133852003345	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1133852003346	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1133852003347	metal binding site [ion binding]; metal-binding site
1133852003348	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1133852003349	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133852003350	Active Sites [active]
1133852003351	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1133852003352	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1133852003353	CysD dimerization site [polypeptide binding]; other site
1133852003354	G1 box; other site
1133852003355	putative GEF interaction site [polypeptide binding]; other site
1133852003356	GTP/Mg2+ binding site [chemical binding]; other site
1133852003357	Switch I region; other site
1133852003358	G2 box; other site
1133852003359	G3 box; other site
1133852003360	Switch II region; other site
1133852003361	G4 box; other site
1133852003362	G5 box; other site
1133852003363	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1133852003364	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1133852003365	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1133852003366	ligand-binding site [chemical binding]; other site
1133852003367	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1133852003368	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1133852003369	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1133852003370	substrate binding site; other site
1133852003371	dimer interface; other site
1133852003372	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1133852003373	homotrimer interaction site [polypeptide binding]; other site
1133852003374	zinc binding site [ion binding]; other site
1133852003375	CDP-binding sites; other site
1133852003376	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1133852003377	Permutation of conserved domain; other site
1133852003378	active site
1133852003379	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1133852003380	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852003381	S-adenosylmethionine binding site [chemical binding]; other site
1133852003382	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1133852003383	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852003384	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133852003385	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1133852003386	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1133852003387	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133852003388	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1133852003389	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133852003390	DNA binding residues [nucleotide binding]
1133852003391	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133852003392	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1133852003393	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1133852003394	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1133852003395	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1133852003396	putative transporter; Provisional; Region: PRK09821
1133852003397	GntP family permease; Region: GntP_permease; pfam02447
1133852003398	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
1133852003399	hypothetical protein; Provisional; Region: PRK09989
1133852003400	putative aldolase; Validated; Region: PRK08130
1133852003401	intersubunit interface [polypeptide binding]; other site
1133852003402	active site
1133852003403	Zn2+ binding site [ion binding]; other site
1133852003404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1133852003405	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1133852003406	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
1133852003407	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
1133852003408	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133852003409	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133852003410	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852003411	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1133852003412	active site
1133852003413	metal binding site [ion binding]; metal-binding site
1133852003414	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1133852003415	MutS domain I; Region: MutS_I; pfam01624
1133852003416	MutS domain II; Region: MutS_II; pfam05188
1133852003417	MutS domain III; Region: MutS_III; pfam05192
1133852003418	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1133852003419	Walker A/P-loop; other site
1133852003420	ATP binding site [chemical binding]; other site
1133852003421	Q-loop/lid; other site
1133852003422	ABC transporter signature motif; other site
1133852003423	Walker B; other site
1133852003424	D-loop; other site
1133852003425	H-loop/switch region; other site
1133852003426	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1133852003427	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1133852003428	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133852003429	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133852003430	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852003431	Walker A motif; other site
1133852003432	ATP binding site [chemical binding]; other site
1133852003433	Walker B motif; other site
1133852003434	arginine finger; other site
1133852003435	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1133852003436	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1133852003437	dimerization interface [polypeptide binding]; other site
1133852003438	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1133852003439	ATP binding site [chemical binding]; other site
1133852003440	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1133852003441	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1133852003442	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1133852003443	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1133852003444	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1133852003445	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1133852003446	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133852003447	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852003448	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852003449	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1133852003450	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852003451	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1133852003452	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1133852003453	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1133852003454	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1133852003455	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1133852003456	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852003457	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1133852003458	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1133852003459	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1133852003460	nickel binding site [ion binding]; other site
1133852003461	Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499
1133852003462	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852003463	non-specific DNA binding site [nucleotide binding]; other site
1133852003464	salt bridge; other site
1133852003465	sequence-specific DNA binding site [nucleotide binding]; other site
1133852003466	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852003467	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852003468	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852003469	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1133852003470	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
1133852003471	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1133852003472	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852003473	active site turn [active]
1133852003474	phosphorylation site [posttranslational modification]
1133852003475	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1133852003476	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133852003477	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852003478	DNA binding site [nucleotide binding]
1133852003479	domain linker motif; other site
1133852003480	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1133852003481	dimerization interface (closed form) [polypeptide binding]; other site
1133852003482	ligand binding site [chemical binding]; other site
1133852003483	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1133852003484	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852003485	Acylphosphatase; Region: Acylphosphatase; pfam00708
1133852003486	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
1133852003487	HypF finger; Region: zf-HYPF; pfam07503
1133852003488	HypF finger; Region: zf-HYPF; pfam07503
1133852003489	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1133852003490	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1133852003491	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852003492	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1133852003493	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1133852003494	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
1133852003495	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1133852003496	iron binding site [ion binding]; other site
1133852003497	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1133852003498	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133852003499	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852003500	Walker A motif; other site
1133852003501	ATP binding site [chemical binding]; other site
1133852003502	Walker B motif; other site
1133852003503	arginine finger; other site
1133852003504	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1133852003505	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1133852003506	putative active site [active]
1133852003507	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1133852003508	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1133852003509	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852003510	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852003511	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1133852003512	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1133852003513	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1133852003514	putative NAD(P) binding site [chemical binding]; other site
1133852003515	active site
1133852003516	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1133852003517	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1133852003518	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1133852003519	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1133852003520	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1133852003521	murein hydrolase B; Provisional; Region: PRK10760
1133852003522	lytic murein transglycosylase B; Region: MltB; TIGR02282
1133852003523	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852003524	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852003525	hypothetical protein; Validated; Region: PRK03661
1133852003526	recombinase A; Provisional; Region: recA; PRK09354
1133852003527	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1133852003528	hexamer interface [polypeptide binding]; other site
1133852003529	Walker A motif; other site
1133852003530	ATP binding site [chemical binding]; other site
1133852003531	Walker B motif; other site
1133852003532	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1133852003533	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1133852003534	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1133852003535	motif 1; other site
1133852003536	active site
1133852003537	motif 2; other site
1133852003538	motif 3; other site
1133852003539	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1133852003540	DHHA1 domain; Region: DHHA1; pfam02272
1133852003541	carbon storage regulator; Provisional; Region: PRK01712
1133852003542	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
1133852003543	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852003544	active site
1133852003545	motif I; other site
1133852003546	motif II; other site
1133852003547	Predicted membrane protein [Function unknown]; Region: COG1238
1133852003548	glutamate--cysteine ligase; Provisional; Region: PRK02107
1133852003549	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1133852003550	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1133852003551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003552	putative substrate translocation pore; other site
1133852003553	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1133852003554	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852003555	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852003556	transcriptional repressor MprA; Provisional; Region: PRK10870
1133852003557	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133852003558	putative L-valine exporter; Provisional; Region: PRK10408
1133852003559	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1133852003560	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1133852003561	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003562	putative substrate translocation pore; other site
1133852003563	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1133852003564	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133852003565	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852003566	dimer interface [polypeptide binding]; other site
1133852003567	conserved gate region; other site
1133852003568	putative PBP binding loops; other site
1133852003569	ABC-ATPase subunit interface; other site
1133852003570	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1133852003571	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1133852003572	Walker A/P-loop; other site
1133852003573	ATP binding site [chemical binding]; other site
1133852003574	Q-loop/lid; other site
1133852003575	ABC transporter signature motif; other site
1133852003576	Walker B; other site
1133852003577	D-loop; other site
1133852003578	H-loop/switch region; other site
1133852003579	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1133852003580	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1133852003581	dimer interface [polypeptide binding]; other site
1133852003582	putative radical transfer pathway; other site
1133852003583	diiron center [ion binding]; other site
1133852003584	tyrosyl radical; other site
1133852003585	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1133852003586	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1133852003587	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1133852003588	active site
1133852003589	dimer interface [polypeptide binding]; other site
1133852003590	catalytic residues [active]
1133852003591	effector binding site; other site
1133852003592	R2 peptide binding site; other site
1133852003593	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1133852003594	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1133852003595	catalytic residues [active]
1133852003596	hypothetical protein; Provisional; Region: PRK10132
1133852003597	hypothetical protein; Provisional; Region: PRK10556
1133852003598	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1133852003599	Domain in histone-like proteins of HNS family; Region: HNS; cl19571
1133852003600	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1133852003601	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
1133852003602	active site residue [active]
1133852003603	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1133852003604	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852003605	dimerization interface [polypeptide binding]; other site
1133852003606	putative DNA binding site [nucleotide binding]; other site
1133852003607	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133852003608	putative Zn2+ binding site [ion binding]; other site
1133852003609	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1133852003610	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1133852003611	bacterial OsmY and nodulation domain; Region: BON; smart00749
1133852003612	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852003613	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1133852003614	helix_turn_helix gluconate operon transcriptional repressor; Region: HTH_GNTR; smart00345
1133852003615	DNA-binding site [nucleotide binding]; DNA binding site
1133852003616	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852003617	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1133852003618	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852003619	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852003620	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1133852003621	inhibitor-cofactor binding pocket; inhibition site
1133852003622	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852003623	catalytic residue [active]
1133852003624	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1133852003625	tetramerization interface [polypeptide binding]; other site
1133852003626	NAD(P) binding site [chemical binding]; other site
1133852003627	catalytic residues [active]
1133852003628	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1133852003629	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1133852003630	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1133852003631	substrate binding pocket [chemical binding]; other site
1133852003632	active site
1133852003633	iron coordination sites [ion binding]; other site
1133852003634	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1133852003635	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1133852003636	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1133852003637	active site
1133852003638	catalytic site [active]
1133852003639	HTH-like domain; Region: HTH_21; pfam13276
1133852003640	Integrase core domain; Region: rve; pfam00665
1133852003641	DDE domain; Region: DDE_Tnp_IS240; pfam13610
1133852003642	Integrase core domain; Region: rve_3; pfam13683
1133852003643	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852003644	Transposase; Region: HTH_Tnp_1; cl17663
1133852003645	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133852003646	integrase; Provisional; Region: PRK09692
1133852003647	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852003648	active site
1133852003649	Int/Topo IB signature motif; other site
1133852003650	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1133852003651	SmpB-tmRNA interface; other site
1133852003652	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1133852003653	putative coenzyme Q binding site [chemical binding]; other site
1133852003654	hypothetical protein; Validated; Region: PRK01777
1133852003655	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1133852003656	recombination and repair protein; Provisional; Region: PRK10869
1133852003657	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1133852003658	Walker A/P-loop; other site
1133852003659	ATP binding site [chemical binding]; other site
1133852003660	Q-loop/lid; other site
1133852003661	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1133852003662	Q-loop/lid; other site
1133852003663	ABC transporter signature motif; other site
1133852003664	Walker B; other site
1133852003665	D-loop; other site
1133852003666	H-loop/switch region; other site
1133852003667	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1133852003668	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; cl19511
1133852003669	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1133852003670	dimer interface [polypeptide binding]; other site
1133852003671	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1133852003672	hypothetical protein; Provisional; Region: PRK11573
1133852003673	Domain of unknown function DUF21; Region: DUF21; pfam01595
1133852003674	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133852003675	Transporter associated domain; Region: CorC_HlyC; smart01091
1133852003676	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1133852003677	signal recognition particle protein; Provisional; Region: PRK10867
1133852003678	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1133852003679	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1133852003680	P loop; other site
1133852003681	GTP binding site [chemical binding]; other site
1133852003682	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1133852003683	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1133852003684	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1133852003685	RimM N-terminal domain; Region: RimM; pfam01782
1133852003686	PRC-barrel domain; Region: PRC; pfam05239
1133852003687	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1133852003688	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1133852003689	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1133852003690	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133852003691	ligand binding site [chemical binding]; other site
1133852003692	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1133852003693	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852003694	metal binding site [ion binding]; metal-binding site
1133852003695	active site
1133852003696	I-site; other site
1133852003697	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1133852003698	lipoprotein; Provisional; Region: PRK11443
1133852003699	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1133852003700	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1133852003701	Chorismate mutase type II; Region: CM_2; cl00693
1133852003702	prephenate dehydrogenase; Validated; Region: PRK08507
1133852003703	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1133852003704	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1133852003705	Prephenate dehydratase; Region: PDT; pfam00800
1133852003706	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1133852003707	putative L-Phe binding site [chemical binding]; other site
1133852003708	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1133852003709	30S subunit binding site; other site
1133852003710	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1133852003711	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1133852003712	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1133852003713	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852003714	RNA binding surface [nucleotide binding]; other site
1133852003715	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1133852003716	active site
1133852003717	hypothetical protein; Provisional; Region: PRK10723
1133852003718	protein disaggregation chaperone; Provisional; Region: PRK10865
1133852003719	Clp amino terminal domain; Region: Clp_N; pfam02861
1133852003720	Clp amino terminal domain; Region: Clp_N; pfam02861
1133852003721	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852003722	Walker A motif; other site
1133852003723	ATP binding site [chemical binding]; other site
1133852003724	Walker B motif; other site
1133852003725	arginine finger; other site
1133852003726	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852003727	Walker A motif; other site
1133852003728	ATP binding site [chemical binding]; other site
1133852003729	Walker B motif; other site
1133852003730	arginine finger; other site
1133852003731	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1133852003732	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1133852003733	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003734	putative substrate translocation pore; other site
1133852003735	lipoprotein; Provisional; Region: PRK10759
1133852003736	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1133852003737	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1133852003738	domain interface [polypeptide binding]; other site
1133852003739	putative active site [active]
1133852003740	catalytic site [active]
1133852003741	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1133852003742	domain interface [polypeptide binding]; other site
1133852003743	putative active site [active]
1133852003744	catalytic site [active]
1133852003745	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1133852003746	CoA binding domain; Region: CoA_binding_2; pfam13380
1133852003747	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1133852003748	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1133852003749	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1133852003750	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1133852003751	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1133852003752	thioredoxin 2; Provisional; Region: PRK10996
1133852003753	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1133852003754	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1133852003755	catalytic residues [active]
1133852003756	putative methyltransferase; Provisional; Region: PRK10864
1133852003757	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1133852003758	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1133852003759	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1133852003760	ligand binding site [chemical binding]; other site
1133852003761	active site
1133852003762	UGI interface [polypeptide binding]; other site
1133852003763	catalytic site [active]
1133852003764	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1133852003765	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1133852003766	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852003767	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852003768	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133852003769	dimerization interface [polypeptide binding]; other site
1133852003770	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852003771	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1133852003772	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133852003773	ATP binding site [chemical binding]; other site
1133852003774	Mg++ binding site [ion binding]; other site
1133852003775	motif III; other site
1133852003776	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852003777	nucleotide binding region [chemical binding]; other site
1133852003778	ATP-binding site [chemical binding]; other site
1133852003779	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1133852003780	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852003781	S-adenosylmethionine binding site [chemical binding]; other site
1133852003782	L-aspartate oxidase; Provisional; Region: PRK09077
1133852003783	L-aspartate oxidase; Provisional; Region: PRK06175
1133852003784	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1133852003785	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1133852003786	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133852003787	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133852003788	DNA binding residues [nucleotide binding]
1133852003789	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1133852003790	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1133852003791	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1133852003792	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1133852003793	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1133852003794	GTP-binding protein LepA; Provisional; Region: PRK05433
1133852003795	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1133852003796	G1 box; other site
1133852003797	putative GEF interaction site [polypeptide binding]; other site
1133852003798	GTP/Mg2+ binding site [chemical binding]; other site
1133852003799	Switch I region; other site
1133852003800	G2 box; other site
1133852003801	G3 box; other site
1133852003802	Switch II region; other site
1133852003803	G4 box; other site
1133852003804	G5 box; other site
1133852003805	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1133852003806	Elongation Factor G, domain II; Region: EFG_II; pfam14492
1133852003807	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1133852003808	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1133852003809	signal peptidase I; Provisional; Region: PRK10861
1133852003810	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1133852003811	Catalytic site [active]
1133852003812	ribonuclease III; Reviewed; Region: rnc; PRK00102
1133852003813	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1133852003814	dimerization interface [polypeptide binding]; other site
1133852003815	active site
1133852003816	metal binding site [ion binding]; metal-binding site
1133852003817	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1133852003818	dsRNA binding site [nucleotide binding]; other site
1133852003819	GTPase Era; Reviewed; Region: era; PRK00089
1133852003820	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1133852003821	G1 box; other site
1133852003822	GTP/Mg2+ binding site [chemical binding]; other site
1133852003823	Switch I region; other site
1133852003824	G2 box; other site
1133852003825	Switch II region; other site
1133852003826	G3 box; other site
1133852003827	G4 box; other site
1133852003828	G5 box; other site
1133852003829	KH domain; Region: KH_2; pfam07650
1133852003830	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1133852003831	Recombination protein O N terminal; Region: RecO_N; pfam11967
1133852003832	Recombination protein O C terminal; Region: RecO_C; pfam02565
1133852003833	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1133852003834	active site
1133852003835	hydrophilic channel; other site
1133852003836	dimerization interface [polypeptide binding]; other site
1133852003837	catalytic residues [active]
1133852003838	active site lid [active]
1133852003839	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
1133852003840	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1133852003841	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133852003842	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1133852003843	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133852003844	putative active site [active]
1133852003845	hypothetical protein; Provisional; Region: PRK11590
1133852003846	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1133852003847	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1133852003848	nucleoside/Zn binding site; other site
1133852003849	dimer interface [polypeptide binding]; other site
1133852003850	catalytic motif [active]
1133852003851	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1133852003852	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852003853	substrate binding pocket [chemical binding]; other site
1133852003854	membrane-bound complex binding site; other site
1133852003855	hinge residues; other site
1133852003856	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852003857	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852003858	catalytic residue [active]
1133852003859	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1133852003860	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1133852003861	dimerization interface [polypeptide binding]; other site
1133852003862	ATP binding site [chemical binding]; other site
1133852003863	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1133852003864	dimerization interface [polypeptide binding]; other site
1133852003865	ATP binding site [chemical binding]; other site
1133852003866	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1133852003867	putative active site [active]
1133852003868	catalytic triad [active]
1133852003869	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1133852003870	HAMP domain; Region: HAMP; pfam00672
1133852003871	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852003872	dimer interface [polypeptide binding]; other site
1133852003873	phosphorylation site [posttranslational modification]
1133852003874	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852003875	ATP binding site [chemical binding]; other site
1133852003876	Mg2+ binding site [ion binding]; other site
1133852003877	G-X-G motif; other site
1133852003878	hypothetical protein; Provisional; Region: PRK10722
1133852003879	response regulator GlrR; Provisional; Region: PRK15115
1133852003880	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852003881	active site
1133852003882	phosphorylation site [posttranslational modification]
1133852003883	intermolecular recognition site; other site
1133852003884	dimerization interface [polypeptide binding]; other site
1133852003885	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852003886	Walker A motif; other site
1133852003887	ATP binding site [chemical binding]; other site
1133852003888	Walker B motif; other site
1133852003889	arginine finger; other site
1133852003890	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1133852003891	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1133852003892	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1133852003893	heme-binding site [chemical binding]; other site
1133852003894	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1133852003895	FAD binding pocket [chemical binding]; other site
1133852003896	FAD binding motif [chemical binding]; other site
1133852003897	phosphate binding motif [ion binding]; other site
1133852003898	beta-alpha-beta structure motif; other site
1133852003899	NAD binding pocket [chemical binding]; other site
1133852003900	Heme binding  pocket [chemical binding]; other site
1133852003901	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1133852003902	dimer interface [polypeptide binding]; other site
1133852003903	active site
1133852003904	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1133852003905	folate binding site [chemical binding]; other site
1133852003906	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1133852003907	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133852003908	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852003909	nucleotide binding site [chemical binding]; other site
1133852003910	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852003911	TPR motif; other site
1133852003912	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1133852003913	binding surface
1133852003914	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852003915	binding surface
1133852003916	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1133852003917	TPR motif; other site
1133852003918	TPR repeat; Region: TPR_11; pfam13414
1133852003919	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852003920	TPR motif; other site
1133852003921	binding surface
1133852003922	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1133852003923	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1133852003924	ligand binding site [chemical binding]; other site
1133852003925	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1133852003926	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852003927	Walker A/P-loop; other site
1133852003928	ATP binding site [chemical binding]; other site
1133852003929	Q-loop/lid; other site
1133852003930	ABC transporter signature motif; other site
1133852003931	Walker B; other site
1133852003932	D-loop; other site
1133852003933	H-loop/switch region; other site
1133852003934	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852003935	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852003936	TM-ABC transporter signature motif; other site
1133852003937	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852003938	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
1133852003939	putative NAD(P) binding site [chemical binding]; other site
1133852003940	catalytic Zn binding site [ion binding]; other site
1133852003941	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
1133852003942	active site
1133852003943	catalytic residues [active]
1133852003944	Predicted membrane protein [Function unknown]; Region: COG2259
1133852003945	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
1133852003946	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133852003947	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852003948	Reductase C-terminal; Region: Reductase_C; pfam14759
1133852003949	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
1133852003950	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
1133852003951	NAD binding site [chemical binding]; other site
1133852003952	active site
1133852003953	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
1133852003954	[2Fe-2S] cluster binding site [ion binding]; other site
1133852003955	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
1133852003956	inter-subunit interface; other site
1133852003957	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1133852003958	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1133852003959	iron-sulfur cluster [ion binding]; other site
1133852003960	[2Fe-2S] cluster binding site [ion binding]; other site
1133852003961	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
1133852003962	beta subunit interface [polypeptide binding]; other site
1133852003963	alpha subunit interface [polypeptide binding]; other site
1133852003964	active site
1133852003965	substrate binding site [chemical binding]; other site
1133852003966	Fe binding site [ion binding]; other site
1133852003967	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1133852003968	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852003969	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
1133852003970	putative dimerization interface [polypeptide binding]; other site
1133852003971	putative substrate binding pocket [chemical binding]; other site
1133852003972	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852003973	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1133852003974	putative substrate translocation pore; other site
1133852003975	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1133852003976	PRD domain; Region: PRD; pfam00874
1133852003977	PRD domain; Region: PRD; pfam00874
1133852003978	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1133852003979	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
1133852003980	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1133852003981	active site
1133852003982	dimerization interface [polypeptide binding]; other site
1133852003983	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1133852003984	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1133852003985	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1133852003986	Rrf2 family protein; Region: rrf2_super; TIGR00738
1133852003987	cysteine desulfurase; Provisional; Region: PRK14012
1133852003988	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852003989	catalytic residue [active]
1133852003990	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1133852003991	trimerization site [polypeptide binding]; other site
1133852003992	active site
1133852003993	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1133852003994	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1133852003995	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133852003996	HSP70 interaction site [polypeptide binding]; other site
1133852003997	HSCB C-terminal oligomerization domain; Region: HSCB_C; pfam07743
1133852003998	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1133852003999	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1133852004000	nucleotide binding site [chemical binding]; other site
1133852004001	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1133852004002	SBD interface [polypeptide binding]; other site
1133852004003	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852004004	catalytic loop [active]
1133852004005	iron binding site [ion binding]; other site
1133852004006	hypothetical protein; Provisional; Region: PRK10721
1133852004007	aminopeptidase B; Provisional; Region: PRK05015
1133852004008	Peptidase; Region: DUF3663; pfam12404
1133852004009	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1133852004010	interface (dimer of trimers) [polypeptide binding]; other site
1133852004011	Substrate-binding/catalytic site; other site
1133852004012	Zn-binding sites [ion binding]; other site
1133852004013	SseB protein N-terminal domain; Region: SseB; pfam07179
1133852004014	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1133852004015	SseB protein C-terminal domain; Region: SseB_C; pfam14581
1133852004016	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1133852004017	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1133852004018	active site residue [active]
1133852004019	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1133852004020	active site residue [active]
1133852004021	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1133852004022	MG2 domain; Region: A2M_N; pfam01835
1133852004023	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
1133852004024	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1133852004025	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1133852004026	surface patch; other site
1133852004027	thioester region; other site
1133852004028	specificity defining residues; other site
1133852004029	penicillin-binding protein 1C; Provisional; Region: PRK11240
1133852004030	Transglycosylase; Region: Transgly; pfam00912
1133852004031	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1133852004032	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1133852004033	Nucleoside diphosphate kinase; Region: NDK; pfam00334
1133852004034	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1133852004035	active site
1133852004036	multimer interface [polypeptide binding]; other site
1133852004037	23S rRNA m2A2503 methyltransferase; Region: TIGR00048
1133852004038	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852004039	FeS/SAM binding site; other site
1133852004040	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1133852004041	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852004042	non-specific DNA binding site [nucleotide binding]; other site
1133852004043	salt bridge; other site
1133852004044	sequence-specific DNA binding site [nucleotide binding]; other site
1133852004045	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1133852004046	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1133852004047	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612
1133852004048	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1133852004049	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1133852004050	dimer interface [polypeptide binding]; other site
1133852004051	motif 1; other site
1133852004052	active site
1133852004053	motif 2; other site
1133852004054	motif 3; other site
1133852004055	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1133852004056	anticodon binding site; other site
1133852004057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1133852004058	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4649
1133852004059	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1133852004060	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
1133852004061	Trp docking motif [polypeptide binding]; other site
1133852004062	active site
1133852004063	GTP-binding protein Der; Reviewed; Region: PRK00093
1133852004064	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1133852004065	G1 box; other site
1133852004066	GTP/Mg2+ binding site [chemical binding]; other site
1133852004067	Switch I region; other site
1133852004068	G2 box; other site
1133852004069	Switch II region; other site
1133852004070	G3 box; other site
1133852004071	G4 box; other site
1133852004072	G5 box; other site
1133852004073	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1133852004074	G1 box; other site
1133852004075	GTP/Mg2+ binding site [chemical binding]; other site
1133852004076	Switch I region; other site
1133852004077	G2 box; other site
1133852004078	G3 box; other site
1133852004079	Switch II region; other site
1133852004080	G4 box; other site
1133852004081	G5 box; other site
1133852004082	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714
1133852004083	zinc-ribbons; Region: zinc-ribbons_6; pfam07191
1133852004084	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1133852004085	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1133852004086	generic binding surface II; other site
1133852004087	generic binding surface I; other site
1133852004088	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1133852004089	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1133852004090	active site
1133852004091	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1133852004092	GMP synthase; Reviewed; Region: guaA; PRK00074
1133852004093	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1133852004094	AMP/PPi binding site [chemical binding]; other site
1133852004095	candidate oxyanion hole; other site
1133852004096	catalytic triad [active]
1133852004097	potential glutamine specificity residues [chemical binding]; other site
1133852004098	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1133852004099	ATP Binding subdomain [chemical binding]; other site
1133852004100	Ligand Binding sites [chemical binding]; other site
1133852004101	Dimerization subdomain; other site
1133852004102	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1133852004103	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1133852004104	MASE1; Region: MASE1; pfam05231
1133852004105	diguanylate cyclase; Region: GGDEF; smart00267
1133852004106	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852004107	exopolyphosphatase; Provisional; Region: PRK10854
1133852004108	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1133852004109	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1133852004110	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1133852004111	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1133852004112	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
1133852004113	domain interface [polypeptide binding]; other site
1133852004114	active site
1133852004115	catalytic site [active]
1133852004116	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1133852004117	domain interface [polypeptide binding]; other site
1133852004118	active site
1133852004119	catalytic site [active]
1133852004120	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1133852004121	active site
1133852004122	substrate binding site [chemical binding]; other site
1133852004123	cosubstrate binding site; other site
1133852004124	catalytic site [active]
1133852004125	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1133852004126	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1133852004127	dimerization interface [polypeptide binding]; other site
1133852004128	putative ATP binding site [chemical binding]; other site
1133852004129	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852004130	active site
1133852004131	uracil transporter; Provisional; Region: PRK10720
1133852004132	uracil-xanthine permease; Region: ncs2; TIGR00801
1133852004133	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1133852004134	DNA replication initiation factor; Provisional; Region: PRK08084
1133852004135	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1133852004136	catalytic residues [active]
1133852004137	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1133852004138	Peptidase family M48; Region: Peptidase_M48; cl12018
1133852004139	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1133852004140	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1133852004141	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
1133852004142	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1133852004143	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852004144	Walker A motif; other site
1133852004145	ATP binding site [chemical binding]; other site
1133852004146	Walker B motif; other site
1133852004147	arginine finger; other site
1133852004148	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133852004149	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1133852004150	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1133852004151	hydrogenase 4 subunit H; Validated; Region: PRK08222
1133852004152	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852004153	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1133852004154	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1133852004155	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1133852004156	hydrogenase 4 subunit F; Validated; Region: PRK06458
1133852004157	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852004158	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
1133852004159	hydrogenase 4 subunit D; Validated; Region: PRK06525
1133852004160	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852004161	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1133852004162	NADH dehydrogenase; Region: NADHdh; cl00469
1133852004163	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1133852004164	hydrogenase 4 subunit B; Validated; Region: PRK06521
1133852004165	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852004166	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1133852004167	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852004168	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1133852004169	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1133852004170	catalytic triad [active]
1133852004171	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1133852004172	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1133852004173	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1133852004174	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1133852004175	dimer interface [polypeptide binding]; other site
1133852004176	active site
1133852004177	catalytic residue [active]
1133852004178	lipoprotein; Provisional; Region: PRK11679
1133852004179	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1133852004180	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1133852004181	ATP binding site [chemical binding]; other site
1133852004182	active site
1133852004183	substrate binding site [chemical binding]; other site
1133852004184	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1133852004185	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1133852004186	oligomeric interface; other site
1133852004187	putative active site [active]
1133852004188	homodimer interface [polypeptide binding]; other site
1133852004189	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1133852004190	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1133852004191	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
1133852004192	Helicase; Region: Helicase_RecD; pfam05127
1133852004193	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1133852004194	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1133852004195	putative hydrolase; Provisional; Region: PRK11460
1133852004196	Predicted esterase [General function prediction only]; Region: COG0400
1133852004197	hypothetical protein; Provisional; Region: PRK13664
1133852004198	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1133852004199	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1133852004200	metal binding site [ion binding]; metal-binding site
1133852004201	dimer interface [polypeptide binding]; other site
1133852004202	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1133852004203	putative catalytic residues [active]
1133852004204	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1133852004205	MMPL family; Region: MMPL; cl14618
1133852004206	MMPL family; Region: MMPL; cl14618
1133852004207	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1133852004208	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1133852004209	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852004210	dimerization interface [polypeptide binding]; other site
1133852004211	Histidine kinase; Region: HisKA_3; pfam07730
1133852004212	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852004213	ATP binding site [chemical binding]; other site
1133852004214	Mg2+ binding site [ion binding]; other site
1133852004215	G-X-G motif; other site
1133852004216	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1133852004217	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852004218	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
1133852004219	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852004220	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852004221	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1133852004222	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1133852004223	dimer interface [polypeptide binding]; other site
1133852004224	ADP-ribose binding site [chemical binding]; other site
1133852004225	active site
1133852004226	nudix motif; other site
1133852004227	metal binding site [ion binding]; metal-binding site
1133852004228	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1133852004229	transketolase; Reviewed; Region: PRK12753
1133852004230	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1133852004231	TPP-binding site [chemical binding]; other site
1133852004232	dimer interface [polypeptide binding]; other site
1133852004233	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1133852004234	PYR/PP interface [polypeptide binding]; other site
1133852004235	dimer interface [polypeptide binding]; other site
1133852004236	TPP binding site [chemical binding]; other site
1133852004237	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1133852004238	transaldolase-like protein; Provisional; Region: PTZ00411
1133852004239	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1133852004240	active site
1133852004241	dimer interface [polypeptide binding]; other site
1133852004242	catalytic residue [active]
1133852004243	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1133852004244	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1133852004245	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1133852004246	putative NAD(P) binding site [chemical binding]; other site
1133852004247	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1133852004248	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1133852004249	putative hexamer interface [polypeptide binding]; other site
1133852004250	putative hexagonal pore; other site
1133852004251	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1133852004252	G1 box; other site
1133852004253	GTP/Mg2+ binding site [chemical binding]; other site
1133852004254	G2 box; other site
1133852004255	Switch I region; other site
1133852004256	G3 box; other site
1133852004257	Switch II region; other site
1133852004258	G4 box; other site
1133852004259	G5 box; other site
1133852004260	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1133852004261	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1133852004262	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1133852004263	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1133852004264	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1133852004265	Hexamer interface [polypeptide binding]; other site
1133852004266	Hexagonal pore residue; other site
1133852004267	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1133852004268	Hexamer/Pentamer interface [polypeptide binding]; other site
1133852004269	central pore; other site
1133852004270	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1133852004271	putative catalytic cysteine [active]
1133852004272	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1133852004273	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852004274	nucleotide binding site [chemical binding]; other site
1133852004275	nucleotide binding site [chemical binding]; other site
1133852004276	Cell division protein FtsA; Region: FtsA; cl17206
1133852004277	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1133852004278	active site
1133852004279	metal binding site [ion binding]; metal-binding site
1133852004280	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1133852004281	Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition [Amino acid transport and metabolism]; Region: EutA; COG4819
1133852004282	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1133852004283	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1133852004284	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1133852004285	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
1133852004286	Hexamer interface [polypeptide binding]; other site
1133852004287	Hexagonal pore residue; other site
1133852004288	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1133852004289	putative hexamer interface [polypeptide binding]; other site
1133852004290	putative hexagonal pore; other site
1133852004291	carboxysome structural protein EutK; Provisional; Region: PRK15466
1133852004292	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1133852004293	Hexamer interface [polypeptide binding]; other site
1133852004294	Hexagonal pore residue; other site
1133852004295	transcriptional regulator EutR; Provisional; Region: PRK10130
1133852004296	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852004297	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1133852004298	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1133852004299	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1133852004300	active site
1133852004301	metal binding site [ion binding]; metal-binding site
1133852004302	putative acetyltransferase; Provisional; Region: PRK03624
1133852004303	Uncharacterized conserved protein [Function unknown]; Region: COG3375
1133852004304	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852004305	Coenzyme A binding pocket [chemical binding]; other site
1133852004306	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1133852004307	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1133852004308	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1133852004309	putative periplasmic esterase; Provisional; Region: PRK03642
1133852004310	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1133852004311	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852004312	active site turn [active]
1133852004313	phosphorylation site [posttranslational modification]
1133852004314	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133852004315	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
1133852004316	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1133852004317	putative active site [active]
1133852004318	transcriptional regulator MurR; Provisional; Region: PRK15482
1133852004319	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133852004320	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133852004321	putative active site [active]
1133852004322	short chain dehydrogenase; Provisional; Region: PRK08226
1133852004323	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1133852004324	NAD binding site [chemical binding]; other site
1133852004325	homotetramer interface [polypeptide binding]; other site
1133852004326	homodimer interface [polypeptide binding]; other site
1133852004327	active site
1133852004328	thiosulfate transporter subunit; Provisional; Region: PRK10852
1133852004329	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1133852004330	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852004331	dimer interface [polypeptide binding]; other site
1133852004332	conserved gate region; other site
1133852004333	putative PBP binding loops; other site
1133852004334	ABC-ATPase subunit interface; other site
1133852004335	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1133852004336	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852004337	dimer interface [polypeptide binding]; other site
1133852004338	conserved gate region; other site
1133852004339	putative PBP binding loops; other site
1133852004340	ABC-ATPase subunit interface; other site
1133852004341	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1133852004342	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1133852004343	Walker A/P-loop; other site
1133852004344	ATP binding site [chemical binding]; other site
1133852004345	Q-loop/lid; other site
1133852004346	ABC transporter signature motif; other site
1133852004347	Walker B; other site
1133852004348	D-loop; other site
1133852004349	H-loop/switch region; other site
1133852004350	TOBE-like domain; Region: TOBE_3; pfam12857
1133852004351	cysteine synthase; Region: PLN02565
1133852004352	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1133852004353	dimer interface [polypeptide binding]; other site
1133852004354	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852004355	catalytic residue [active]
1133852004356	hypothetical protein; Provisional; Region: PRK10318
1133852004357	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1133852004358	dimer interface [polypeptide binding]; other site
1133852004359	pyridoxal binding site [chemical binding]; other site
1133852004360	ATP binding site [chemical binding]; other site
1133852004361	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1133852004362	HPr interaction site; other site
1133852004363	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1133852004364	active site
1133852004365	phosphorylation site [posttranslational modification]
1133852004366	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1133852004367	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
1133852004368	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133852004369	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133852004370	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133852004371	dimerization domain swap beta strand [polypeptide binding]; other site
1133852004372	regulatory protein interface [polypeptide binding]; other site
1133852004373	active site
1133852004374	regulatory phosphorylation site [posttranslational modification]; other site
1133852004375	cysteine synthase; Region: PLN02565
1133852004376	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1133852004377	dimer interface [polypeptide binding]; other site
1133852004378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852004379	catalytic residue [active]
1133852004380	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1133852004381	cell division protein ZipA; Provisional; Region: PRK03427
1133852004382	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1133852004383	FtsZ protein binding site [polypeptide binding]; other site
1133852004384	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1133852004385	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1133852004386	nucleotide binding pocket [chemical binding]; other site
1133852004387	K-X-D-G motif; other site
1133852004388	catalytic site [active]
1133852004389	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1133852004390	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1133852004391	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
1133852004392	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
1133852004393	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1133852004394	Dimer interface [polypeptide binding]; other site
1133852004395	BRCT sequence motif; other site
1133852004396	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1133852004397	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1133852004398	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852004399	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852004400	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1133852004401	putative dimerization interface [polypeptide binding]; other site
1133852004402	hypothetical protein; Provisional; Region: PRK11528
1133852004403	Purine nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pnp; COG0005
1133852004404	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1133852004405	nucleoside transporter; Region: 2A0110; TIGR00889
1133852004406	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1133852004407	XapX domain; Region: XapX; TIGR03510
1133852004408	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1133852004409	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852004410	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1133852004411	putative dimerization interface [polypeptide binding]; other site
1133852004412	putative substrate binding pocket [chemical binding]; other site
1133852004413	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1133852004414	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1133852004415	active site
1133852004416	HIGH motif; other site
1133852004417	KMSKS motif; other site
1133852004418	Protein of unknown function (DUF3150); Region: DUF3150; pfam11348
1133852004419	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852004420	salt bridge; other site
1133852004421	non-specific DNA binding site [nucleotide binding]; other site
1133852004422	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1133852004423	sequence-specific DNA binding site [nucleotide binding]; other site
1133852004424	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1133852004425	MASE1; Region: MASE1; pfam05231
1133852004426	diguanylate cyclase; Region: GGDEF; smart00267
1133852004427	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852004428	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1133852004429	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1133852004430	Nucleoside recognition; Region: Gate; pfam07670
1133852004431	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1133852004432	manganese transport protein MntH; Reviewed; Region: PRK00701
1133852004433	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1133852004434	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1133852004435	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1133852004436	Cl- selectivity filter; other site
1133852004437	Cl- binding residues [ion binding]; other site
1133852004438	pore gating glutamate residue; other site
1133852004439	dimer interface [polypeptide binding]; other site
1133852004440	glucokinase; Provisional; Region: glk; PRK00292
1133852004441	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852004442	nucleotide binding site [chemical binding]; other site
1133852004443	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133852004444	active site
1133852004445	P-loop; other site
1133852004446	phosphorylation site [posttranslational modification]
1133852004447	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1133852004448	aminopeptidase; Provisional; Region: PRK09795
1133852004449	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1133852004450	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1133852004451	active site
1133852004452	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
1133852004453	oligomer interface [polypeptide binding]; other site
1133852004454	active site
1133852004455	metal binding site [ion binding]; metal-binding site
1133852004456	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133852004457	dimerization domain swap beta strand [polypeptide binding]; other site
1133852004458	regulatory protein interface [polypeptide binding]; other site
1133852004459	active site
1133852004460	regulatory phosphorylation site [posttranslational modification]; other site
1133852004461	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
1133852004462	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1133852004463	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133852004464	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133852004465	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852004466	active site
1133852004467	phosphorylation site [posttranslational modification]
1133852004468	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852004469	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852004470	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1133852004471	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852004472	active site
1133852004473	phosphorylation site [posttranslational modification]
1133852004474	intermolecular recognition site; other site
1133852004475	dimerization interface [polypeptide binding]; other site
1133852004476	LytTr DNA-binding domain; Region: LytTR; pfam04397
1133852004477	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1133852004478	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1133852004479	GAF domain; Region: GAF; pfam01590
1133852004480	Histidine kinase; Region: His_kinase; pfam06580
1133852004481	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852004482	ATP binding site [chemical binding]; other site
1133852004483	Mg2+ binding site [ion binding]; other site
1133852004484	G-X-G motif; other site
1133852004485	aminotransferase; Validated; Region: PRK08175
1133852004486	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852004487	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852004488	homodimer interface [polypeptide binding]; other site
1133852004489	catalytic residue [active]
1133852004490	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133852004491	putative acyl-acceptor binding pocket; other site
1133852004492	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1133852004493	hypothetical protein; Provisional; Region: PRK10316
1133852004494	YfdX protein; Region: YfdX; pfam10938
1133852004495	formyl-coenzyme A transferase; Provisional; Region: PRK05398
1133852004496	oxalyl-CoA decarboxylase; Region: oxalate_oxc; TIGR03254
1133852004497	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133852004498	PYR/PP interface [polypeptide binding]; other site
1133852004499	dimer interface [polypeptide binding]; other site
1133852004500	TPP binding site [chemical binding]; other site
1133852004501	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133852004502	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
1133852004503	TPP-binding site; other site
1133852004504	dimer interface [polypeptide binding]; other site
1133852004505	putative transporter YfdV; Provisional; Region: PRK09903
1133852004506	putative CoA-transferase; Provisional; Region: PRK11430
1133852004507	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
1133852004508	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852004509	substrate binding pocket [chemical binding]; other site
1133852004510	membrane-bound complex binding site; other site
1133852004511	hinge residues; other site
1133852004512	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852004513	substrate binding pocket [chemical binding]; other site
1133852004514	membrane-bound complex binding site; other site
1133852004515	hinge residues; other site
1133852004516	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852004517	dimer interface [polypeptide binding]; other site
1133852004518	phosphorylation site [posttranslational modification]
1133852004519	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852004520	ATP binding site [chemical binding]; other site
1133852004521	Mg2+ binding site [ion binding]; other site
1133852004522	G-X-G motif; other site
1133852004523	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852004524	active site
1133852004525	phosphorylation site [posttranslational modification]
1133852004526	intermolecular recognition site; other site
1133852004527	dimerization interface [polypeptide binding]; other site
1133852004528	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133852004529	putative binding surface; other site
1133852004530	active site
1133852004531	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
1133852004532	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852004533	active site
1133852004534	phosphorylation site [posttranslational modification]
1133852004535	intermolecular recognition site; other site
1133852004536	dimerization interface [polypeptide binding]; other site
1133852004537	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852004538	DNA binding residues [nucleotide binding]
1133852004539	dimerization interface [polypeptide binding]; other site
1133852004540	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1133852004541	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852004542	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852004543	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1133852004544	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852004545	putative substrate translocation pore; other site
1133852004546	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1133852004547	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852004548	catalytic residue [active]
1133852004549	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1133852004550	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852004551	DNA binding site [nucleotide binding]
1133852004552	domain linker motif; other site
1133852004553	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1133852004554	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1133852004555	putative dimerization interface [polypeptide binding]; other site
1133852004556	putative ligand binding site [chemical binding]; other site
1133852004557	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1133852004558	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1133852004559	substrate binding [chemical binding]; other site
1133852004560	active site
1133852004561	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1133852004562	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1133852004563	putative substrate binding site [chemical binding]; other site
1133852004564	putative ATP binding site [chemical binding]; other site
1133852004565	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1133852004566	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852004567	putative substrate translocation pore; other site
1133852004568	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1133852004569	hypothetical protein; Region: PHA00626
1133852004570	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133852004571	Protein of unknown function (DUF2737); Region: DUF2737; pfam10930
1133852004572	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
1133852004573	ERF superfamily; Region: ERF; pfam04404
1133852004574	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
1133852004575	Lambda Phage CIII; Region: Lambda_CIII; pfam02061
1133852004576	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852004577	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852004578	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852004579	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852004580	Protein of unknown function (DUF2560); Region: DUF2560; pfam10834
1133852004581	Phage terminase large subunit; Region: Terminase_3; pfam04466
1133852004582	Bacteriophage, scaffolding protein; Region: Phage-scaffold; pfam09306
1133852004583	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
1133852004584	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
1133852004585	Phage stabilisation protein; Region: Phage_stabilize; pfam11134
1133852004586	Rab effector MyRIP/melanophilin C-terminus; Region: Rab_eff_C; pfam04698
1133852004587	Protein of unknown function (DUF2824); Region: DUF2824; pfam11039
1133852004588	Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; Region: DM14; smart00685
1133852004589	Arc-like DNA binding domain; Region: Arc; pfam03869
1133852004590	Arc-like DNA binding domain; Region: Arc; pfam03869
1133852004591	Prophage antirepressor [Transcription]; Region: COG3617
1133852004592	BRO family, N-terminal domain; Region: Bro-N; smart01040
1133852004593	Phage anti-repressor protein [Transcription]; Region: COG3561
1133852004594	Head binding; Region: Head_binding; pfam09008
1133852004595	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1133852004596	integrase; Provisional; Region: PRK09692
1133852004597	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852004598	active site
1133852004599	Int/Topo IB signature motif; other site
1133852004600	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1133852004601	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1133852004602	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1133852004603	conserved hypothetical protein; Region: TIGR00743
1133852004604	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1133852004605	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133852004606	dimer interface [polypeptide binding]; other site
1133852004607	active site
1133852004608	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1133852004609	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852004610	substrate binding site [chemical binding]; other site
1133852004611	oxyanion hole (OAH) forming residues; other site
1133852004612	trimer interface [polypeptide binding]; other site
1133852004613	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1133852004614	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133852004615	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133852004616	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133852004617	catalytic core [active]
1133852004618	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133852004619	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1133852004620	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852004621	Outer membrane usher protein; Region: Usher; pfam00577
1133852004622	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852004623	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852004624	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852004625	Fimbrial protein; Region: Fimbrial; cl01416
1133852004626	Fimbrial protein; Region: Fimbrial; cl01416
1133852004627	Fimbrial protein; Region: Fimbrial; cl01416
1133852004628	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
1133852004629	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852004630	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852004631	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852004632	hypothetical protein; Provisional; Region: PRK04946
1133852004633	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1133852004634	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK11805
1133852004635	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852004636	S-adenosylmethionine binding site [chemical binding]; other site
1133852004637	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1133852004638	Tetramer interface [polypeptide binding]; other site
1133852004639	active site
1133852004640	FMN-binding site [chemical binding]; other site
1133852004641	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1133852004642	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1133852004643	hypothetical protein; Provisional; Region: PRK10621
1133852004644	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1133852004645	YfcL protein; Region: YfcL; pfam08891
1133852004646	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1133852004647	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1133852004648	tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; Region: MnmC_Cterm; TIGR03197
1133852004649	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1133852004650	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1133852004651	dimer interface [polypeptide binding]; other site
1133852004652	active site
1133852004653	putative transporter; Provisional; Region: PRK12382
1133852004654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852004655	putative substrate translocation pore; other site
1133852004656	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1133852004657	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1133852004658	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1133852004659	ligand binding site [chemical binding]; other site
1133852004660	NAD binding site [chemical binding]; other site
1133852004661	catalytic site [active]
1133852004662	homodimer interface [polypeptide binding]; other site
1133852004663	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1133852004664	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
1133852004665	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
1133852004666	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1133852004667	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1133852004668	dimerization interface 3.5A [polypeptide binding]; other site
1133852004669	active site
1133852004670	hypothetical protein; Provisional; Region: PRK10847
1133852004671	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1133852004672	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1133852004673	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133852004674	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133852004675	cell division protein DedD; Provisional; Region: PRK11633
1133852004676	Sporulation related domain; Region: SPOR; pfam05036
1133852004677	colicin V production protein; Provisional; Region: PRK10845
1133852004678	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1133852004679	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1133852004680	active site
1133852004681	tetramer interface [polypeptide binding]; other site
1133852004682	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852004683	active site
1133852004684	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1133852004685	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1133852004686	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852004687	substrate binding pocket [chemical binding]; other site
1133852004688	membrane-bound complex binding site; other site
1133852004689	hinge residues; other site
1133852004690	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1133852004691	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852004692	substrate binding pocket [chemical binding]; other site
1133852004693	membrane-bound complex binding site; other site
1133852004694	hinge residues; other site
1133852004695	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133852004696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852004697	dimer interface [polypeptide binding]; other site
1133852004698	conserved gate region; other site
1133852004699	putative PBP binding loops; other site
1133852004700	ABC-ATPase subunit interface; other site
1133852004701	ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160
1133852004702	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852004703	dimer interface [polypeptide binding]; other site
1133852004704	conserved gate region; other site
1133852004705	putative PBP binding loops; other site
1133852004706	ABC-ATPase subunit interface; other site
1133852004707	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1133852004708	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133852004709	Walker A/P-loop; other site
1133852004710	ATP binding site [chemical binding]; other site
1133852004711	Q-loop/lid; other site
1133852004712	ABC transporter signature motif; other site
1133852004713	Walker B; other site
1133852004714	D-loop; other site
1133852004715	H-loop/switch region; other site
1133852004716	putative transposase; Provisional; Region: PRK09857
1133852004717	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133852004718	FlgN protein; Region: FlgN; pfam05130
1133852004719	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1133852004720	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1133852004721	putative NAD(P) binding site [chemical binding]; other site
1133852004722	putative active site [active]
1133852004723	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1133852004724	homooctamer interface [polypeptide binding]; other site
1133852004725	active site
1133852004726	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1133852004727	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1133852004728	C-terminal domain interface [polypeptide binding]; other site
1133852004729	GSH binding site (G-site) [chemical binding]; other site
1133852004730	dimer interface [polypeptide binding]; other site
1133852004731	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1133852004732	N-terminal domain interface [polypeptide binding]; other site
1133852004733	putative dimer interface [polypeptide binding]; other site
1133852004734	active site
1133852004735	glutathione S-transferase; Provisional; Region: PRK15113
1133852004736	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1133852004737	C-terminal domain interface [polypeptide binding]; other site
1133852004738	GSH binding site (G-site) [chemical binding]; other site
1133852004739	dimer interface [polypeptide binding]; other site
1133852004740	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1133852004741	N-terminal domain interface [polypeptide binding]; other site
1133852004742	putative dimer interface [polypeptide binding]; other site
1133852004743	putative substrate binding pocket (H-site) [chemical binding]; other site
1133852004744	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1133852004745	active site
1133852004746	metal binding site [ion binding]; metal-binding site
1133852004747	homotetramer interface [polypeptide binding]; other site
1133852004748	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1133852004749	nudix motif; other site
1133852004750	hypothetical protein; Provisional; Region: PRK11588
1133852004751	phosphate acetyltransferase; Reviewed; Region: PRK05632
1133852004752	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1133852004753	DRTGG domain; Region: DRTGG; pfam07085
1133852004754	phosphate acetyltransferase; Region: pta; TIGR00651
1133852004755	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1133852004756	hypothetical protein; Provisional; Region: PRK01816
1133852004757	hypothetical protein; Validated; Region: PRK05445
1133852004758	putative phosphatase; Provisional; Region: PRK11587
1133852004759	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852004760	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852004761	active site
1133852004762	motif I; other site
1133852004763	motif II; other site
1133852004764	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1133852004765	transmembrane helices; other site
1133852004766	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133852004767	TrkA-C domain; Region: TrkA_C; pfam02080
1133852004768	TrkA-C domain; Region: TrkA_C; pfam02080
1133852004769	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1133852004770	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133852004771	Zn2+ binding site [ion binding]; other site
1133852004772	Mg2+ binding site [ion binding]; other site
1133852004773	aminotransferase AlaT; Validated; Region: PRK09265
1133852004774	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852004775	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852004776	homodimer interface [polypeptide binding]; other site
1133852004777	catalytic residue [active]
1133852004778	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1133852004779	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852004780	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1133852004781	putative dimerization interface [polypeptide binding]; other site
1133852004782	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1133852004783	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1133852004784	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
1133852004785	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1133852004786	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
1133852004787	NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion]; Region: NuoE; COG1905
1133852004788	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1133852004789	putative dimer interface [polypeptide binding]; other site
1133852004790	[2Fe-2S] cluster binding site [ion binding]; other site
1133852004791	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1133852004792	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1133852004793	SLBB domain; Region: SLBB; pfam10531
1133852004794	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1133852004795	NADH dehydrogenase subunit G; Validated; Region: PRK08166
1133852004796	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852004797	catalytic loop [active]
1133852004798	iron binding site [ion binding]; other site
1133852004799	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1133852004800	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1133852004801	[4Fe-4S] binding site [ion binding]; other site
1133852004802	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1133852004803	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1133852004804	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1133852004805	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852004806	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1133852004807	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1133852004808	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1133852004809	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1133852004810	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1133852004811	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852004812	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1133852004813	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852004814	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1133852004815	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1133852004816	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
1133852004817	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1133852004818	potential frameshift: common BLAST hit: gi|218695872|ref|YP_002403539.1| deubiquitinase
1133852004819	ribonuclease BN; Region: true_RNase_BN; TIGR02649
1133852004820	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852004821	Coenzyme A binding pocket [chemical binding]; other site
1133852004822	hypothetical protein; Provisional; Region: PRK10404
1133852004823	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1133852004824	isochorismate synthases; Region: isochor_syn; TIGR00543
1133852004825	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1133852004826	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1133852004827	dimer interface [polypeptide binding]; other site
1133852004828	tetramer interface [polypeptide binding]; other site
1133852004829	PYR/PP interface [polypeptide binding]; other site
1133852004830	TPP binding site [chemical binding]; other site
1133852004831	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1133852004832	TPP-binding site; other site
1133852004833	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1133852004834	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
1133852004835	dihydroxynaphthoic acid synthetase; Validated; Region: PRK07396
1133852004836	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852004837	substrate binding site [chemical binding]; other site
1133852004838	oxyanion hole (OAH) forming residues; other site
1133852004839	trimer interface [polypeptide binding]; other site
1133852004840	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1133852004841	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1133852004842	active site
1133852004843	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1133852004844	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1133852004845	acyl-activating enzyme (AAE) consensus motif; other site
1133852004846	putative AMP binding site [chemical binding]; other site
1133852004847	putative active site [active]
1133852004848	putative CoA binding site [chemical binding]; other site
1133852004849	signal transduction protein PmrD; Provisional; Region: PRK15450
1133852004850	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1133852004851	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1133852004852	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1133852004853	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1133852004854	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1133852004855	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1133852004856	putative active site [active]
1133852004857	putative catalytic site [active]
1133852004858	putative Zn binding site [ion binding]; other site
1133852004859	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1133852004860	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
1133852004861	substrate binding site [chemical binding]; other site
1133852004862	cosubstrate binding site; other site
1133852004863	catalytic site [active]
1133852004864	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1133852004865	active site
1133852004866	hexamer interface [polypeptide binding]; other site
1133852004867	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1133852004868	NAD binding site [chemical binding]; other site
1133852004869	substrate binding site [chemical binding]; other site
1133852004870	active site
1133852004871	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1133852004872	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1133852004873	Ligand binding site; other site
1133852004874	Putative Catalytic site; other site
1133852004875	DXD motif; other site
1133852004876	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1133852004877	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1133852004878	inhibitor-cofactor binding pocket; inhibition site
1133852004879	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852004880	catalytic residue [active]
1133852004881	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1133852004882	catalytic core [active]
1133852004883	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1133852004884	YfaZ precursor; Region: YfaZ; pfam07437
1133852004885	hypothetical protein; Provisional; Region: PRK03673
1133852004886	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1133852004887	putative MPT binding site; other site
1133852004888	Competence-damaged protein; Region: CinA; cl00666
1133852004889	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1133852004890	hypothetical protein; Provisional; Region: PRK09956
1133852004891	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133852004892	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1133852004893	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1133852004894	Cysteine-rich domain; Region: CCG; pfam02754
1133852004895	Cysteine-rich domain; Region: CCG; pfam02754
1133852004896	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1133852004897	FAD binding domain; Region: FAD_binding_2; pfam00890
1133852004898	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1133852004899	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852004900	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1133852004901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852004902	putative substrate translocation pore; other site
1133852004903	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1133852004904	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1133852004905	active site
1133852004906	catalytic site [active]
1133852004907	metal binding site [ion binding]; metal-binding site
1133852004908	hypothetical protein; Provisional; Region: PRK09729
1133852004909	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852004910	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852004911	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852004912	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133852004913	hypothetical protein; Provisional; Region: PRK09902
1133852004914	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852004915	catalytic loop [active]
1133852004916	iron binding site [ion binding]; other site
1133852004917	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1133852004918	dimer interface [polypeptide binding]; other site
1133852004919	putative radical transfer pathway; other site
1133852004920	diiron center [ion binding]; other site
1133852004921	tyrosyl radical; other site
1133852004922	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1133852004923	ATP cone domain; Region: ATP-cone; pfam03477
1133852004924	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1133852004925	active site
1133852004926	dimer interface [polypeptide binding]; other site
1133852004927	catalytic residues [active]
1133852004928	effector binding site; other site
1133852004929	R2 peptide binding site; other site
1133852004930	adhesin; Provisional; Region: PRK09752
1133852004931	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133852004932	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852004933	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1133852004934	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852004935	S-adenosylmethionine binding site [chemical binding]; other site
1133852004936	DNA gyrase subunit A; Validated; Region: PRK05560
1133852004937	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1133852004938	CAP-like domain; other site
1133852004939	active site
1133852004940	primary dimer interface [polypeptide binding]; other site
1133852004941	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852004942	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852004943	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852004944	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852004945	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852004946	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1133852004947	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
1133852004948	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
1133852004949	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1133852004950	MG2 domain; Region: A2M_N; pfam01835
1133852004951	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1133852004952	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1133852004953	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
1133852004954	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1133852004955	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
1133852004956	Predicted secreted protein [Function unknown]; Region: COG5445
1133852004957	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
1133852004958	Predicted secreted protein [Function unknown]; Region: COG5445
1133852004959	Stage II sporulation protein; Region: SpoIID; pfam08486
1133852004960	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
1133852004961	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
1133852004962	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1133852004963	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852004964	dimer interface [polypeptide binding]; other site
1133852004965	phosphorylation site [posttranslational modification]
1133852004966	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852004967	ATP binding site [chemical binding]; other site
1133852004968	Mg2+ binding site [ion binding]; other site
1133852004969	G-X-G motif; other site
1133852004970	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1133852004971	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852004972	active site
1133852004973	phosphorylation site [posttranslational modification]
1133852004974	intermolecular recognition site; other site
1133852004975	dimerization interface [polypeptide binding]; other site
1133852004976	transcriptional regulator RcsB; Provisional; Region: PRK10840
1133852004977	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852004978	active site
1133852004979	phosphorylation site [posttranslational modification]
1133852004980	intermolecular recognition site; other site
1133852004981	dimerization interface [polypeptide binding]; other site
1133852004982	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852004983	DNA binding residues [nucleotide binding]
1133852004984	dimerization interface [polypeptide binding]; other site
1133852004985	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1133852004986	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852004987	ATP binding site [chemical binding]; other site
1133852004988	Mg2+ binding site [ion binding]; other site
1133852004989	G-X-G motif; other site
1133852004990	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133852004991	putative binding surface; other site
1133852004992	active site
1133852004993	outer membrane porin protein C; Provisional; Region: PRK10554
1133852004994	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1133852004995	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1133852004996	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1133852004997	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852004998	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852004999	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1133852005000	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1133852005001	DNA binding site [nucleotide binding]
1133852005002	active site
1133852005003	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1133852005004	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1133852005005	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1133852005006	Walker A/P-loop; other site
1133852005007	ATP binding site [chemical binding]; other site
1133852005008	Q-loop/lid; other site
1133852005009	ABC transporter signature motif; other site
1133852005010	Walker B; other site
1133852005011	D-loop; other site
1133852005012	H-loop/switch region; other site
1133852005013	malate:quinone oxidoreductase; Validated; Region: PRK05257
1133852005014	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1133852005015	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1133852005016	secondary substrate binding site; other site
1133852005017	primary substrate binding site; other site
1133852005018	inhibition loop; other site
1133852005019	dimerization interface [polypeptide binding]; other site
1133852005020	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1133852005021	ferredoxin-type protein; Provisional; Region: PRK10194
1133852005022	ferredoxin-type protein NapF; Region: napF; TIGR00402
1133852005023	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1133852005024	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1133852005025	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1133852005026	[4Fe-4S] binding site [ion binding]; other site
1133852005027	molybdopterin cofactor binding site; other site
1133852005028	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1133852005029	molybdopterin cofactor binding site; other site
1133852005030	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1133852005031	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852005032	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852005033	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852005034	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1133852005035	lysophospholipid transporter LplT; Provisional; Region: PRK11195; cl19150
1133852005036	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1133852005037	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852005038	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1133852005039	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1133852005040	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
1133852005041	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1133852005042	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1133852005043	Walker A/P-loop; other site
1133852005044	ATP binding site [chemical binding]; other site
1133852005045	Q-loop/lid; other site
1133852005046	ABC transporter signature motif; other site
1133852005047	Walker B; other site
1133852005048	D-loop; other site
1133852005049	H-loop/switch region; other site
1133852005050	heme exporter protein CcmB; Region: ccmB; TIGR01190
1133852005051	heme exporter protein CcmC; Region: ccmC; TIGR01191
1133852005052	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1133852005053	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1133852005054	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1133852005055	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1133852005056	catalytic residues [active]
1133852005057	central insert; other site
1133852005058	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1133852005059	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1133852005060	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852005061	binding surface
1133852005062	TPR motif; other site
1133852005063	transcriptional regulator NarP; Provisional; Region: PRK10403
1133852005064	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852005065	active site
1133852005066	phosphorylation site [posttranslational modification]
1133852005067	intermolecular recognition site; other site
1133852005068	dimerization interface [polypeptide binding]; other site
1133852005069	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852005070	DNA binding residues [nucleotide binding]
1133852005071	dimerization interface [polypeptide binding]; other site
1133852005072	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133852005073	hypothetical protein; Provisional; Region: PRK09945
1133852005074	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133852005075	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852005076	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852005077	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852005078	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1133852005079	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1133852005080	Sulfatase; Region: Sulfatase; pfam00884
1133852005081	hypothetical protein; Provisional; Region: PRK13689
1133852005082	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1133852005083	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1133852005084	5S rRNA interface [nucleotide binding]; other site
1133852005085	CTC domain interface [polypeptide binding]; other site
1133852005086	L16 interface [polypeptide binding]; other site
1133852005087	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133852005088	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852005089	ATP binding site [chemical binding]; other site
1133852005090	putative Mg++ binding site [ion binding]; other site
1133852005091	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852005092	nucleotide binding region [chemical binding]; other site
1133852005093	ATP-binding site [chemical binding]; other site
1133852005094	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1133852005095	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1133852005096	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852005097	RNA binding surface [nucleotide binding]; other site
1133852005098	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1133852005099	active site
1133852005100	uracil binding [chemical binding]; other site
1133852005101	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852005102	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1133852005103	putative substrate translocation pore; other site
1133852005104	hypothetical protein; Provisional; Region: PRK11835
1133852005105	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1133852005106	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852005107	Walker A/P-loop; other site
1133852005108	ATP binding site [chemical binding]; other site
1133852005109	Q-loop/lid; other site
1133852005110	ABC transporter signature motif; other site
1133852005111	Walker B; other site
1133852005112	D-loop; other site
1133852005113	H-loop/switch region; other site
1133852005114	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852005115	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852005116	Walker A/P-loop; other site
1133852005117	ATP binding site [chemical binding]; other site
1133852005118	Q-loop/lid; other site
1133852005119	ABC transporter signature motif; other site
1133852005120	Walker B; other site
1133852005121	D-loop; other site
1133852005122	H-loop/switch region; other site
1133852005123	microcin C ABC transporter permease; Provisional; Region: PRK15021
1133852005124	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852005125	dimer interface [polypeptide binding]; other site
1133852005126	conserved gate region; other site
1133852005127	putative PBP binding loops; other site
1133852005128	ABC-ATPase subunit interface; other site
1133852005129	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1133852005130	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852005131	dimer interface [polypeptide binding]; other site
1133852005132	conserved gate region; other site
1133852005133	putative PBP binding loops; other site
1133852005134	ABC-ATPase subunit interface; other site
1133852005135	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1133852005136	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1133852005137	phage resistance protein; Provisional; Region: PRK10551
1133852005138	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133852005139	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852005140	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1133852005141	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133852005142	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133852005143	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1133852005144	active site
1133852005145	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1133852005146	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1133852005147	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1133852005148	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1133852005149	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133852005150	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133852005151	elongation factor P; Provisional; Region: PRK04542
1133852005152	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1133852005153	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1133852005154	RNA binding site [nucleotide binding]; other site
1133852005155	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1133852005156	RNA binding site [nucleotide binding]; other site
1133852005157	Putative zinc- or iron-chelating domain; Region: CxxCxxCC; pfam03692
1133852005158	sugar efflux transporter B; Provisional; Region: PRK15011
1133852005159	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852005160	putative substrate translocation pore; other site
1133852005161	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1133852005162	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852005163	active site
1133852005164	phosphorylation site [posttranslational modification]
1133852005165	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133852005166	dimerization domain swap beta strand [polypeptide binding]; other site
1133852005167	regulatory protein interface [polypeptide binding]; other site
1133852005168	active site
1133852005169	regulatory phosphorylation site [posttranslational modification]; other site
1133852005170	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1133852005171	putative substrate binding site [chemical binding]; other site
1133852005172	putative ATP binding site [chemical binding]; other site
1133852005173	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1133852005174	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1133852005175	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133852005176	active site
1133852005177	P-loop; other site
1133852005178	phosphorylation site [posttranslational modification]
1133852005179	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1133852005180	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1133852005181	substrate binding site [chemical binding]; other site
1133852005182	ATP binding site [chemical binding]; other site
1133852005183	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1133852005184	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1133852005185	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1133852005186	Nucleoside recognition; Region: Gate; pfam07670
1133852005187	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1133852005188	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
1133852005189	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1133852005190	ligand binding site [chemical binding]; other site
1133852005191	flexible hinge region; other site
1133852005192	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1133852005193	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1133852005194	active site
1133852005195	tetramer interface [polypeptide binding]; other site
1133852005196	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1133852005197	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1133852005198	Nucleoside recognition; Region: Gate; pfam07670
1133852005199	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1133852005200	putative kinase; Provisional; Region: PRK09954
1133852005201	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852005202	putative DNA binding site [nucleotide binding]; other site
1133852005203	putative Zn2+ binding site [ion binding]; other site
1133852005204	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1133852005205	substrate binding site [chemical binding]; other site
1133852005206	ATP binding site [chemical binding]; other site
1133852005207	Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648
1133852005208	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1133852005209	AP (apurinic/apyrimidinic) site pocket; other site
1133852005210	DNA interaction; other site
1133852005211	Metal-binding active site; metal-binding site
1133852005212	conserved hypothetical integral membrane protein; Region: TIGR00698
1133852005213	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1133852005214	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852005215	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1133852005216	putative dimerization interface [polypeptide binding]; other site
1133852005217	lysine transporter; Provisional; Region: PRK10836
1133852005218	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852005219	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1133852005220	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852005221	N-terminal plug; other site
1133852005222	ligand-binding site [chemical binding]; other site
1133852005223	Predicted esterase [General function prediction only]; Region: COG0627
1133852005224	S-formylglutathione hydrolase; Region: PLN02442
1133852005225	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1133852005226	homodecamer interface [polypeptide binding]; other site
1133852005227	active site
1133852005228	putative catalytic site residues [active]
1133852005229	zinc binding site [ion binding]; other site
1133852005230	GTP-CH-I/GFRP interaction surface; other site
1133852005231	Predicted membrane protein [Function unknown]; Region: COG2311
1133852005232	hypothetical protein; Provisional; Region: PRK10835
1133852005233	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1133852005234	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852005235	DNA binding site [nucleotide binding]
1133852005236	domain linker motif; other site
1133852005237	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1133852005238	dimerization interface (closed form) [polypeptide binding]; other site
1133852005239	ligand binding site [chemical binding]; other site
1133852005240	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1133852005241	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1133852005242	ligand binding site [chemical binding]; other site
1133852005243	calcium binding site [ion binding]; other site
1133852005244	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852005245	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1133852005246	Walker A/P-loop; other site
1133852005247	ATP binding site [chemical binding]; other site
1133852005248	Q-loop/lid; other site
1133852005249	ABC transporter signature motif; other site
1133852005250	Walker B; other site
1133852005251	D-loop; other site
1133852005252	H-loop/switch region; other site
1133852005253	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852005254	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852005255	TM-ABC transporter signature motif; other site
1133852005256	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1133852005257	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1133852005258	homodimer interface [polypeptide binding]; other site
1133852005259	active site
1133852005260	FMN binding site [chemical binding]; other site
1133852005261	substrate binding site [chemical binding]; other site
1133852005262	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852005263	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1133852005264	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
1133852005265	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1133852005266	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852005267	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1133852005268	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133852005269	putative active site [active]
1133852005270	cytidine deaminase; Provisional; Region: PRK09027
1133852005271	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1133852005272	active site
1133852005273	catalytic motif [active]
1133852005274	Zn binding site [ion binding]; other site
1133852005275	Cytidine and deoxycytidylate deaminase zinc-binding region; Region: dCMP_cyt_deam_2; pfam08211
1133852005276	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1133852005277	active site
1133852005278	catalytic motif [active]
1133852005279	Zn binding site [ion binding]; other site
1133852005280	hypothetical protein; Provisional; Region: PRK10711
1133852005281	hypothetical protein; Provisional; Region: PRK01821
1133852005282	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1133852005283	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
1133852005284	FMN binding site [chemical binding]; other site
1133852005285	active site
1133852005286	catalytic residues [active]
1133852005287	substrate binding site [chemical binding]; other site
1133852005288	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1133852005289	Outer membrane efflux protein; Region: OEP; pfam02321
1133852005290	Outer membrane efflux protein; Region: OEP; pfam02321
1133852005291	oxidoreductase; Provisional; Region: PRK12743
1133852005292	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133852005293	NAD(P) binding site [chemical binding]; other site
1133852005294	active site
1133852005295	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133852005296	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1133852005297	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1133852005298	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1133852005299	D-lactate dehydrogenase; Provisional; Region: PRK11183
1133852005300	FAD binding domain; Region: FAD_binding_4; cl19922
1133852005301	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1133852005302	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1133852005303	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1133852005304	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1133852005305	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1133852005306	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1133852005307	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852005308	dimer interface [polypeptide binding]; other site
1133852005309	conserved gate region; other site
1133852005310	putative PBP binding loops; other site
1133852005311	ABC-ATPase subunit interface; other site
1133852005312	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1133852005313	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1133852005314	Walker A/P-loop; other site
1133852005315	ATP binding site [chemical binding]; other site
1133852005316	Q-loop/lid; other site
1133852005317	ABC transporter signature motif; other site
1133852005318	Walker B; other site
1133852005319	D-loop; other site
1133852005320	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1133852005321	H-loop/switch region; other site
1133852005322	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133852005323	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1133852005324	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852005325	dimer interface [polypeptide binding]; other site
1133852005326	conserved gate region; other site
1133852005327	putative PBP binding loops; other site
1133852005328	ABC-ATPase subunit interface; other site
1133852005329	hypothetical protein; Provisional; Region: PRK13681
1133852005330	transcriptional regulator MirA; Provisional; Region: PRK15043
1133852005331	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1133852005332	DNA binding residues [nucleotide binding]
1133852005333	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1133852005334	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1133852005335	GAF domain; Region: GAF; pfam01590
1133852005336	Histidine kinase; Region: His_kinase; pfam06580
1133852005337	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852005338	ATP binding site [chemical binding]; other site
1133852005339	Mg2+ binding site [ion binding]; other site
1133852005340	G-X-G motif; other site
1133852005341	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1133852005342	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852005343	active site
1133852005344	phosphorylation site [posttranslational modification]
1133852005345	intermolecular recognition site; other site
1133852005346	dimerization interface [polypeptide binding]; other site
1133852005347	LytTr DNA-binding domain; Region: LytTR; pfam04397
1133852005348	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1133852005349	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1133852005350	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1133852005351	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1133852005352	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1133852005353	metal ion-dependent adhesion site (MIDAS); other site
1133852005354	MoxR-like ATPases [General function prediction only]; Region: COG0714
1133852005355	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852005356	Walker A motif; other site
1133852005357	ATP binding site [chemical binding]; other site
1133852005358	Walker B motif; other site
1133852005359	arginine finger; other site
1133852005360	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1133852005361	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
1133852005362	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1133852005363	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1133852005364	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1133852005365	active site
1133852005366	HIGH motif; other site
1133852005367	KMSKS motif; other site
1133852005368	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1133852005369	tRNA binding surface [nucleotide binding]; other site
1133852005370	anticodon binding site; other site
1133852005371	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1133852005372	dimer interface [polypeptide binding]; other site
1133852005373	putative tRNA-binding site [nucleotide binding]; other site
1133852005374	antiporter inner membrane protein; Provisional; Region: PRK11670
1133852005375	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1133852005376	Walker A motif; other site
1133852005377	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1133852005378	Fimbrial protein; Region: Fimbrial; cl01416
1133852005379	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
1133852005380	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852005381	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852005382	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1133852005383	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852005384	Outer membrane usher protein; Region: Usher; pfam00577
1133852005385	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852005386	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1133852005387	Predicted integral membrane protein [Function unknown]; Region: COG5455
1133852005388	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1133852005389	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1133852005390	putative metal binding site [ion binding]; other site
1133852005391	putative homodimer interface [polypeptide binding]; other site
1133852005392	putative homotetramer interface [polypeptide binding]; other site
1133852005393	putative homodimer-homodimer interface [polypeptide binding]; other site
1133852005394	putative allosteric switch controlling residues; other site
1133852005395	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1133852005396	substrate binding site [chemical binding]; other site
1133852005397	multimerization interface [polypeptide binding]; other site
1133852005398	ATP binding site [chemical binding]; other site
1133852005399	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1133852005400	dimer interface [polypeptide binding]; other site
1133852005401	substrate binding site [chemical binding]; other site
1133852005402	ATP binding site [chemical binding]; other site
1133852005403	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
1133852005404	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
1133852005405	active site
1133852005406	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1133852005407	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852005408	DNA-binding site [nucleotide binding]; DNA binding site
1133852005409	UTRA domain; Region: UTRA; pfam07702
1133852005410	YegV-like sugar kinase.  Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YegV_kinase_like; cd01944
1133852005411	substrate binding site [chemical binding]; other site
1133852005412	ATP binding site [chemical binding]; other site
1133852005413	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1133852005414	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1133852005415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852005416	putative substrate translocation pore; other site
1133852005417	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1133852005418	putative active site; other site
1133852005419	catalytic residue [active]
1133852005420	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1133852005421	intersubunit interface [polypeptide binding]; other site
1133852005422	active site
1133852005423	zinc binding site [ion binding]; other site
1133852005424	Na+ binding site [ion binding]; other site
1133852005425	potential frameshift: common BLAST hit: gi|291283341|ref|YP_003500159.1| tagatose 6-phosphate kinase
1133852005426	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852005427	active site
1133852005428	phosphorylation site [posttranslational modification]
1133852005429	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1133852005430	active site
1133852005431	P-loop; other site
1133852005432	phosphorylation site [posttranslational modification]
1133852005433	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1133852005434	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1133852005435	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1133852005436	putative NAD(P) binding site [chemical binding]; other site
1133852005437	catalytic Zn binding site [ion binding]; other site
1133852005438	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133852005439	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133852005440	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852005441	lipid kinase; Reviewed; Region: PRK13054
1133852005442	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1133852005443	putative protease; Provisional; Region: PRK15452
1133852005444	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1133852005445	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1133852005446	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1133852005447	Uncharacterized conserved protein [Function unknown]; Region: COG3422
1133852005448	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1133852005449	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1133852005450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852005451	active site
1133852005452	phosphorylation site [posttranslational modification]
1133852005453	intermolecular recognition site; other site
1133852005454	dimerization interface [polypeptide binding]; other site
1133852005455	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852005456	DNA binding site [nucleotide binding]
1133852005457	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1133852005458	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852005459	dimerization interface [polypeptide binding]; other site
1133852005460	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852005461	dimer interface [polypeptide binding]; other site
1133852005462	phosphorylation site [posttranslational modification]
1133852005463	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852005464	ATP binding site [chemical binding]; other site
1133852005465	Mg2+ binding site [ion binding]; other site
1133852005466	G-X-G motif; other site
1133852005467	putative transporter; Provisional; Region: PRK10504
1133852005468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852005469	putative substrate translocation pore; other site
1133852005470	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1133852005471	MMPL family; Region: MMPL; cl14618
1133852005472	MMPL family; Region: MMPL; cl14618
1133852005473	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1133852005474	MMPL family; Region: MMPL; cl14618
1133852005475	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1133852005476	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852005477	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852005478	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133852005479	metal ion-dependent adhesion site (MIDAS); other site
1133852005480	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1133852005481	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
1133852005482	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1133852005483	substrate binding site [chemical binding]; other site
1133852005484	activation loop (A-loop); other site
1133852005485	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
1133852005486	putative chaperone; Provisional; Region: PRK11678
1133852005487	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1133852005488	nucleotide binding site [chemical binding]; other site
1133852005489	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1133852005490	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1133852005491	SBD interface [polypeptide binding]; other site
1133852005492	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1133852005493	AlkA N-terminal domain; Region: AlkA_N; smart01009
1133852005494	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1133852005495	minor groove reading motif; other site
1133852005496	helix-hairpin-helix signature motif; other site
1133852005497	substrate binding pocket [chemical binding]; other site
1133852005498	active site
1133852005499	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1133852005500	putative diguanylate cyclase; Provisional; Region: PRK09776
1133852005501	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852005502	putative active site [active]
1133852005503	heme pocket [chemical binding]; other site
1133852005504	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852005505	putative active site [active]
1133852005506	heme pocket [chemical binding]; other site
1133852005507	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852005508	putative active site [active]
1133852005509	heme pocket [chemical binding]; other site
1133852005510	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852005511	metal binding site [ion binding]; metal-binding site
1133852005512	active site
1133852005513	I-site; other site
1133852005514	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1133852005515	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1133852005516	ATP-binding site [chemical binding]; other site
1133852005517	Sugar specificity; other site
1133852005518	Pyrimidine base specificity; other site
1133852005519	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1133852005520	trimer interface [polypeptide binding]; other site
1133852005521	active site
1133852005522	putative assembly protein; Provisional; Region: PRK10833
1133852005523	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133852005524	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1133852005525	FOG: CBS domain [General function prediction only]; Region: COG0517
1133852005526	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133852005527	Transporter associated domain; Region: CorC_HlyC; smart01091
1133852005528	polysaccharide export protein Wza; Provisional; Region: PRK15078
1133852005529	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1133852005530	SLBB domain; Region: SLBB; pfam10531
1133852005531	SLBB domain; Region: SLBB; pfam10531
1133852005532	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1133852005533	active site
1133852005534	tyrosine kinase; Provisional; Region: PRK11519
1133852005535	Chain length determinant protein; Region: Wzz; pfam02706
1133852005536	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133852005537	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1133852005538	putative glycosyl transferase; Provisional; Region: PRK10018
1133852005539	colanic acid biosynthesis glycosyl transferase WcaA; Region: WcaA; TIGR04017
1133852005540	active site
1133852005541	putative acyl transferase; Provisional; Region: PRK10191
1133852005542	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1133852005543	trimer interface [polypeptide binding]; other site
1133852005544	active site
1133852005545	substrate binding site [chemical binding]; other site
1133852005546	CoA binding site [chemical binding]; other site
1133852005547	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1133852005548	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1133852005549	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
1133852005550	putative glycosyl transferase; Provisional; Region: PRK10063
1133852005551	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1133852005552	metal-binding site
1133852005553	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1133852005554	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1133852005555	putative trimer interface [polypeptide binding]; other site
1133852005556	putative active site [active]
1133852005557	putative substrate binding site [chemical binding]; other site
1133852005558	putative CoA binding site [chemical binding]; other site
1133852005559	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1133852005560	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1133852005561	NADP-binding site; other site
1133852005562	homotetramer interface [polypeptide binding]; other site
1133852005563	substrate binding site [chemical binding]; other site
1133852005564	homodimer interface [polypeptide binding]; other site
1133852005565	active site
1133852005566	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1133852005567	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1133852005568	NADP binding site [chemical binding]; other site
1133852005569	active site
1133852005570	putative substrate binding site [chemical binding]; other site
1133852005571	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1133852005572	active site
1133852005573	GDP-Mannose binding site [chemical binding]; other site
1133852005574	dimer interface [polypeptide binding]; other site
1133852005575	modified nudix motif
1133852005576	metal binding site [ion binding]; metal-binding site
1133852005577	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1133852005578	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1133852005579	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1133852005580	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1133852005581	Substrate binding site; other site
1133852005582	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1133852005583	phosphomannomutase CpsG; Provisional; Region: PRK15414
1133852005584	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1133852005585	active site
1133852005586	substrate binding site [chemical binding]; other site
1133852005587	metal binding site [ion binding]; metal-binding site
1133852005588	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1133852005589	CoA-binding domain; Region: CoA_binding_3; pfam13727
1133852005590	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1133852005591	colanic acid exporter; Provisional; Region: PRK10459
1133852005592	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1133852005593	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
1133852005594	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
1133852005595	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1133852005596	putative ADP-binding pocket [chemical binding]; other site
1133852005597	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
1133852005598	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1133852005599	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133852005600	putative NAD(P) binding site [chemical binding]; other site
1133852005601	active site
1133852005602	putative substrate binding site [chemical binding]; other site
1133852005603	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1133852005604	active site
1133852005605	tetramer interface; other site
1133852005606	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1133852005607	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1133852005608	putative trimer interface [polypeptide binding]; other site
1133852005609	putative CoA binding site [chemical binding]; other site
1133852005610	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1133852005611	NeuB family; Region: NeuB; pfam03102
1133852005612	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1133852005613	NeuB binding interface [polypeptide binding]; other site
1133852005614	putative substrate binding site [chemical binding]; other site
1133852005615	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1133852005616	ligand binding site; other site
1133852005617	tetramer interface; other site
1133852005618	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
1133852005619	active site
1133852005620	catalytic triad [active]
1133852005621	oxyanion hole [active]
1133852005622	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1133852005623	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1133852005624	active site
1133852005625	homodimer interface [polypeptide binding]; other site
1133852005626	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
1133852005627	EpsG family; Region: EpsG; pfam14897
1133852005628	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1133852005629	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1133852005630	putative ADP-binding pocket [chemical binding]; other site
1133852005631	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1133852005632	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1133852005633	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1133852005634	active site
1133852005635	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
1133852005636	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1133852005637	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1133852005638	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1133852005639	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126
1133852005640	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1133852005641	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1133852005642	chain length determinant protein WzzB; Provisional; Region: PRK15471
1133852005643	Chain length determinant protein; Region: Wzz; pfam02706
1133852005644	Protein-interacting V-domain of mammalian Alix and related domains; Region: V_Alix_like; cl14654
1133852005645	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133852005646	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1133852005647	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1133852005648	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1133852005649	metal binding site [ion binding]; metal-binding site
1133852005650	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1133852005651	substrate binding site [chemical binding]; other site
1133852005652	glutamase interaction surface [polypeptide binding]; other site
1133852005653	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1133852005654	catalytic residues [active]
1133852005655	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142
1133852005656	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1133852005657	putative active site [active]
1133852005658	oxyanion strand; other site
1133852005659	catalytic triad [active]
1133852005660	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1133852005661	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852005662	active site
1133852005663	motif I; other site
1133852005664	motif II; other site
1133852005665	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1133852005666	putative active site pocket [active]
1133852005667	4-fold oligomerization interface [polypeptide binding]; other site
1133852005668	metal binding residues [ion binding]; metal-binding site
1133852005669	3-fold/trimer interface [polypeptide binding]; other site
1133852005670	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
1133852005671	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852005672	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852005673	homodimer interface [polypeptide binding]; other site
1133852005674	catalytic residue [active]
1133852005675	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1133852005676	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1133852005677	NAD binding site [chemical binding]; other site
1133852005678	dimerization interface [polypeptide binding]; other site
1133852005679	product binding site; other site
1133852005680	substrate binding site [chemical binding]; other site
1133852005681	zinc binding site [ion binding]; other site
1133852005682	catalytic residues [active]
1133852005683	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1133852005684	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1133852005685	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1133852005686	antitoxin YefM; Provisional; Region: PRK11409
1133852005687	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
1133852005688	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133852005689	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1133852005690	putative NAD(P) binding site [chemical binding]; other site
1133852005691	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852005692	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1133852005693	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852005694	dimerization interface [polypeptide binding]; other site
1133852005695	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1133852005696	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852005697	Predicted transporter component [General function prediction only]; Region: COG2391
1133852005698	Sulphur transport; Region: Sulf_transp; cl19477
1133852005699	Sulphur transport; Region: Sulf_transp; cl19477
1133852005700	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1133852005701	CPxP  motif; other site
1133852005702	exonuclease I; Provisional; Region: sbcB; PRK11779
1133852005703	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1133852005704	active site
1133852005705	catalytic site [active]
1133852005706	substrate binding site [chemical binding]; other site
1133852005707	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1133852005708	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1133852005709	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1133852005710	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1133852005711	DNA gyrase inhibitor; Provisional; Region: PRK10016
1133852005712	Predicted membrane protein [Function unknown]; Region: COG1289
1133852005713	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133852005714	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852005715	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852005716	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852005717	hypothetical protein; Provisional; Region: PRK05423
1133852005718	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133852005719	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133852005720	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133852005721	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133852005722	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133852005723	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133852005724	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133852005725	MPN+ (JAMM) motif; other site
1133852005726	Zinc-binding site [ion binding]; other site
1133852005727	Antirestriction protein; Region: Antirestrict; pfam03230
1133852005728	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133852005729	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1133852005730	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
1133852005731	active site
1133852005732	nucleophile elbow; other site
1133852005733	YjcZ-like protein; Region: YjcZ; pfam13990
1133852005734	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133852005735	G1 box; other site
1133852005736	GTP/Mg2+ binding site [chemical binding]; other site
1133852005737	G2 box; other site
1133852005738	Switch I region; other site
1133852005739	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1133852005740	G3 box; other site
1133852005741	Switch II region; other site
1133852005742	G4 box; other site
1133852005743	envelope glycoprotein I; Provisional; Region: PHA03291
1133852005744	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852005745	Transposase; Region: HTH_Tnp_1; pfam01527
1133852005746	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852005747	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852005748	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
1133852005749	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133852005750	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852005751	zinc-finger binding domain of transposase IS66; Region: zf-IS66; pfam13005
1133852005752	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852005753	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852005754	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133852005755	Hydrogenase expression/synthesis hypA family; Region: HypA; cl19201
1133852005756	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133852005757	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852005758	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852005759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133852005760	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133852005761	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133852005762	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133852005763	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; cl19223
1133852005764	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; cl19223
1133852005765	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1133852005766	active site
1133852005767	substrate binding pocket [chemical binding]; other site
1133852005768	homodimer interaction site [polypeptide binding]; other site
1133852005769	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1133852005770	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133852005771	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133852005772	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1133852005773	substrate binding site [chemical binding]; other site
1133852005774	dimer interface [polypeptide binding]; other site
1133852005775	ATP binding site [chemical binding]; other site
1133852005776	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852005777	Predicted GTPase [General function prediction only]; Region: COG3596
1133852005778	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1133852005779	homotrimer interface [polypeptide binding]; other site
1133852005780	Walker A motif; other site
1133852005781	GTP binding site [chemical binding]; other site
1133852005782	Walker B motif; other site
1133852005783	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
1133852005784	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1133852005785	putative dimer interface [polypeptide binding]; other site
1133852005786	active site pocket [active]
1133852005787	putative cataytic base [active]
1133852005788	L,D-transpeptidase; Provisional; Region: PRK10190
1133852005789	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133852005790	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1133852005791	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852005792	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1133852005793	putative dimerization interface [polypeptide binding]; other site
1133852005794	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1133852005795	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852005796	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
1133852005797	putative substrate binding site [chemical binding]; other site
1133852005798	dimerization interface [polypeptide binding]; other site
1133852005799	MATE family multidrug exporter; Provisional; Region: PRK10189
1133852005800	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1133852005801	hypothetical protein; Provisional; Region: PRK12378
1133852005802	AMP nucleosidase; Provisional; Region: PRK08292
1133852005803	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1133852005804	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1133852005805	shikimate transporter; Provisional; Region: PRK09952
1133852005806	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852005807	putative substrate translocation pore; other site
1133852005808	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1133852005809	potential frameshift: common BLAST hit: gi|117624169|ref|YP_853082.1| autotransporter
1133852005810	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1133852005811	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1133852005812	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852005813	N-terminal plug; other site
1133852005814	ligand-binding site [chemical binding]; other site
1133852005815	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
1133852005816	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1133852005817	acyl-activating enzyme (AAE) consensus motif; other site
1133852005818	active site
1133852005819	AMP binding site [chemical binding]; other site
1133852005820	substrate binding site [chemical binding]; other site
1133852005821	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1133852005822	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1133852005823	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
1133852005824	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133852005825	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1133852005826	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1133852005827	active site
1133852005828	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1133852005829	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1133852005830	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1133852005831	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
1133852005832	short chain dehydrogenase; Region: adh_short; pfam00106
1133852005833	NADP binding site [chemical binding]; other site
1133852005834	active site
1133852005835	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133852005836	Condensation domain; Region: Condensation; cl19241
1133852005837	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1133852005838	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1133852005839	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1133852005840	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133852005841	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1133852005842	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1133852005843	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1133852005844	Condensation domain; Region: Condensation; pfam00668
1133852005845	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1133852005846	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1133852005847	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
1133852005848	acyl-activating enzyme (AAE) consensus motif; other site
1133852005849	AMP binding site [chemical binding]; other site
1133852005850	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1133852005851	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852005852	S-adenosylmethionine binding site [chemical binding]; other site
1133852005853	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1133852005854	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133852005855	Condensation domain; Region: Condensation; pfam00668
1133852005856	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1133852005857	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133852005858	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852005859	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852005860	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1133852005861	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852005862	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852005863	Walker A/P-loop; other site
1133852005864	ATP binding site [chemical binding]; other site
1133852005865	Q-loop/lid; other site
1133852005866	ABC transporter signature motif; other site
1133852005867	Walker B; other site
1133852005868	D-loop; other site
1133852005869	H-loop/switch region; other site
1133852005870	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1133852005871	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852005872	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852005873	Walker A/P-loop; other site
1133852005874	ATP binding site [chemical binding]; other site
1133852005875	Q-loop/lid; other site
1133852005876	ABC transporter signature motif; other site
1133852005877	Walker B; other site
1133852005878	D-loop; other site
1133852005879	H-loop/switch region; other site
1133852005880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852005881	putative substrate translocation pore; other site
1133852005882	salicylate synthase Irp9; Reviewed; Region: PRK06772
1133852005883	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1133852005884	integrase; Provisional; Region: PRK09692
1133852005885	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852005886	active site
1133852005887	Int/Topo IB signature motif; other site
1133852005888	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1133852005889	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1133852005890	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1133852005891	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
1133852005892	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1133852005893	Moco binding site; other site
1133852005894	metal coordination site [ion binding]; other site
1133852005895	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1133852005896	active site
1133852005897	homotetramer interface [polypeptide binding]; other site
1133852005898	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1133852005899	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852005900	active site
1133852005901	phosphorylation site [posttranslational modification]
1133852005902	intermolecular recognition site; other site
1133852005903	dimerization interface [polypeptide binding]; other site
1133852005904	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852005905	DNA binding site [nucleotide binding]
1133852005906	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1133852005907	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852005908	dimer interface [polypeptide binding]; other site
1133852005909	phosphorylation site [posttranslational modification]
1133852005910	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852005911	ATP binding site [chemical binding]; other site
1133852005912	Mg2+ binding site [ion binding]; other site
1133852005913	G-X-G motif; other site
1133852005914	chaperone protein HchA; Provisional; Region: PRK04155
1133852005915	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1133852005916	conserved cys residue [active]
1133852005917	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852005918	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852005919	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852005920	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852005921	HTH-like domain; Region: HTH_21; pfam13276
1133852005922	Integrase core domain; Region: rve; pfam00665
1133852005923	Integrase core domain; Region: rve_3; pfam13683
1133852005924	putative transposase OrfB; Reviewed; Region: PHA02517
1133852005925	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1133852005926	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133852005927	Homeodomain-like domain; Region: HTH_32; pfam13565
1133852005928	Integrase core domain; Region: rve; pfam00665
1133852005929	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852005930	Transposase; Region: HTH_Tnp_1; pfam01527
1133852005931	potential frameshift: common BLAST hit: gi|218558820|ref|YP_002391733.1| outer membrane protein F precursor (Porin ompF)
1133852005932	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1133852005933	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1133852005934	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133852005935	Zn2+ binding site [ion binding]; other site
1133852005936	Mg2+ binding site [ion binding]; other site
1133852005937	DNA cytosine methylase; Provisional; Region: PRK10458
1133852005938	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1133852005939	cofactor binding site; other site
1133852005940	DNA binding site [nucleotide binding]
1133852005941	substrate interaction site [chemical binding]; other site
1133852005942	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1133852005943	additional DNA contacts [nucleotide binding]; other site
1133852005944	mismatch recognition site; other site
1133852005945	active site
1133852005946	zinc binding site [ion binding]; other site
1133852005947	DNA intercalation site [nucleotide binding]; other site
1133852005948	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1133852005949	EamA-like transporter family; Region: EamA; pfam00892
1133852005950	EamA-like transporter family; Region: EamA; pfam00892
1133852005951	hypothetical protein; Provisional; Region: PRK10062
1133852005952	Uncharacterized small protein [Function unknown]; Region: COG5475
1133852005953	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1133852005954	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852005955	metal binding site [ion binding]; metal-binding site
1133852005956	active site
1133852005957	I-site; other site
1133852005958	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1133852005959	mannosyl-3-phosphoglycerate phosphatase family; Region: HAD-SF-IIB-MPGP; TIGR01486
1133852005960	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852005961	active site
1133852005962	motif I; other site
1133852005963	motif II; other site
1133852005964	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1133852005965	hypothetical protein; Provisional; Region: PRK10708
1133852005966	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1133852005967	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852005968	DNA binding residues [nucleotide binding]
1133852005969	dimerization interface [polypeptide binding]; other site
1133852005970	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1133852005971	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1133852005972	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1133852005973	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1133852005974	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1133852005975	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1133852005976	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1133852005977	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1133852005978	flagellar hook-length control protein; Provisional; Region: PRK10118
1133852005979	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1133852005980	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1133852005981	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1133852005982	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1133852005983	Walker A motif/ATP binding site; other site
1133852005984	Walker B motif; other site
1133852005985	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1133852005986	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1133852005987	Flagellar assembly protein FliH; Region: FliH; pfam02108
1133852005988	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1133852005989	FliG N-terminal domain; Region: FliG_N; pfam14842
1133852005990	FliG middle domain; Region: FliG_M; pfam14841
1133852005991	FliG C-terminal domain; Region: FliG_C; pfam01706
1133852005992	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
1133852005993	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1133852005994	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1133852005995	flagellar hook-basal body complex protein FliE; Region: fliE; TIGR00205
1133852005996	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
1133852005997	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1133852005998	substrate binding site [chemical binding]; other site
1133852005999	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852006000	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
1133852006001	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
1133852006002	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1133852006003	CPxP  motif; other site
1133852006004	putative inner membrane protein; Provisional; Region: PRK11099
1133852006005	Predicted transporter component [General function prediction only]; Region: COG2391
1133852006006	lipoprotein; Provisional; Region: PRK10397
1133852006007	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1133852006008	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1133852006009	active site
1133852006010	Na/Ca binding site [ion binding]; other site
1133852006011	catalytic site [active]
1133852006012	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1133852006013	Flagellar protein FliS; Region: FliS; cl00654
1133852006014	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1133852006015	Flagellar hook-associated protein 2 N-terminus; Region: FliD_N; pfam02465
1133852006016	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1133852006017	flagellin; Validated; Region: PRK08026
1133852006018	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1133852006019	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1133852006020	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1133852006021	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133852006022	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1133852006023	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133852006024	DNA binding residues [nucleotide binding]
1133852006025	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1133852006026	cystine transporter subunit; Provisional; Region: PRK11260
1133852006027	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852006028	substrate binding pocket [chemical binding]; other site
1133852006029	membrane-bound complex binding site; other site
1133852006030	hinge residues; other site
1133852006031	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1133852006032	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852006033	catalytic residue [active]
1133852006034	amino acid ABC transporter permease; Provisional; Region: PRK15100
1133852006035	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852006036	dimer interface [polypeptide binding]; other site
1133852006037	conserved gate region; other site
1133852006038	putative PBP binding loops; other site
1133852006039	ABC-ATPase subunit interface; other site
1133852006040	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1133852006041	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133852006042	Walker A/P-loop; other site
1133852006043	ATP binding site [chemical binding]; other site
1133852006044	Q-loop/lid; other site
1133852006045	ABC transporter signature motif; other site
1133852006046	Walker B; other site
1133852006047	D-loop; other site
1133852006048	H-loop/switch region; other site
1133852006049	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1133852006050	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1133852006051	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852006052	DNA binding residues [nucleotide binding]
1133852006053	dimerization interface [polypeptide binding]; other site
1133852006054	hypothetical protein; Provisional; Region: PRK10613
1133852006055	response regulator; Provisional; Region: PRK09483
1133852006056	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852006057	active site
1133852006058	phosphorylation site [posttranslational modification]
1133852006059	intermolecular recognition site; other site
1133852006060	dimerization interface [polypeptide binding]; other site
1133852006061	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852006062	DNA binding residues [nucleotide binding]
1133852006063	dimerization interface [polypeptide binding]; other site
1133852006064	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1133852006065	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1133852006066	GIY-YIG motif/motif A; other site
1133852006067	active site
1133852006068	catalytic site [active]
1133852006069	putative DNA binding site [nucleotide binding]; other site
1133852006070	metal binding site [ion binding]; metal-binding site
1133852006071	UvrB/uvrC motif; Region: UVR; pfam02151
1133852006072	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1133852006073	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
1133852006074	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1133852006075	hypothetical protein; Provisional; Region: PRK10396
1133852006076	yecA family protein; Region: ygfB_yecA; TIGR02292
1133852006077	SEC-C motif; Region: SEC-C; cl19389
1133852006078	tyrosine transporter TyrP; Provisional; Region: PRK15132
1133852006079	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852006080	probable metal-binding protein; Region: matur_matur; TIGR03853
1133852006081	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1133852006082	Ferritin-like domain; Region: Ferritin; pfam00210
1133852006083	ferroxidase diiron center [ion binding]; other site
1133852006084	YecR-like lipoprotein; Region: YecR; pfam13992
1133852006085	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
1133852006086	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1133852006087	Ferritin-like domain; Region: Ferritin; pfam00210
1133852006088	ferroxidase diiron center [ion binding]; other site
1133852006089	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1133852006090	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1133852006091	ligand binding site [chemical binding]; other site
1133852006092	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1133852006093	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852006094	Walker A/P-loop; other site
1133852006095	ATP binding site [chemical binding]; other site
1133852006096	Q-loop/lid; other site
1133852006097	ABC transporter signature motif; other site
1133852006098	Walker B; other site
1133852006099	D-loop; other site
1133852006100	H-loop/switch region; other site
1133852006101	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852006102	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852006103	TM-ABC transporter signature motif; other site
1133852006104	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1133852006105	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
1133852006106	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1133852006107	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1133852006108	active site
1133852006109	homotetramer interface [polypeptide binding]; other site
1133852006110	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852006111	Ligand Binding Site [chemical binding]; other site
1133852006112	transcriptional activator FlhD; Provisional; Region: PRK02909
1133852006113	transcriptional activator FlhC; Provisional; Region: PRK12722
1133852006114	flagellar motor protein MotA; Validated; Region: PRK09110
1133852006115	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1133852006116	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1133852006117	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133852006118	ligand binding site [chemical binding]; other site
1133852006119	chemotaxis protein CheA; Provisional; Region: PRK10547
1133852006120	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133852006121	putative binding surface; other site
1133852006122	active site
1133852006123	CheY binding; Region: CheY-binding; pfam09078
1133852006124	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1133852006125	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852006126	ATP binding site [chemical binding]; other site
1133852006127	Mg2+ binding site [ion binding]; other site
1133852006128	G-X-G motif; other site
1133852006129	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1133852006130	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1133852006131	putative CheA interaction surface; other site
1133852006132	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1133852006133	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133852006134	dimer interface [polypeptide binding]; other site
1133852006135	ligand binding site [chemical binding]; other site
1133852006136	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852006137	dimerization interface [polypeptide binding]; other site
1133852006138	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133852006139	dimer interface [polypeptide binding]; other site
1133852006140	putative CheW interface [polypeptide binding]; other site
1133852006141	methyl-accepting protein IV; Provisional; Region: PRK09793
1133852006142	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133852006143	dimer interface [polypeptide binding]; other site
1133852006144	ligand binding site [chemical binding]; other site
1133852006145	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852006146	dimerization interface [polypeptide binding]; other site
1133852006147	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133852006148	dimer interface [polypeptide binding]; other site
1133852006149	putative CheW interface [polypeptide binding]; other site
1133852006150	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1133852006151	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1133852006152	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006153	S-adenosylmethionine binding site [chemical binding]; other site
1133852006154	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1133852006155	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852006156	active site
1133852006157	phosphorylation site [posttranslational modification]
1133852006158	intermolecular recognition site; other site
1133852006159	dimerization interface [polypeptide binding]; other site
1133852006160	CheB methylesterase; Region: CheB_methylest; pfam01339
1133852006161	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852006162	active site
1133852006163	phosphorylation site [posttranslational modification]
1133852006164	intermolecular recognition site; other site
1133852006165	dimerization interface [polypeptide binding]; other site
1133852006166	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1133852006167	FlhB HrpN YscU SpaS Family; Region: Bac_export_2; cl19167
1133852006168	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1133852006169	Flagellar protein FlhE; Region: FlhE; pfam06366
1133852006170	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1133852006171	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1133852006172	arginyl-tRNA synthetase; Region: argS; TIGR00456
1133852006173	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1133852006174	active site
1133852006175	HIGH motif; other site
1133852006176	KMSK motif region; other site
1133852006177	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1133852006178	tRNA binding surface [nucleotide binding]; other site
1133852006179	anticodon binding site; other site
1133852006180	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1133852006181	putative metal binding site [ion binding]; other site
1133852006182	copper homeostasis protein CutC; Provisional; Region: PRK11572
1133852006183	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
1133852006184	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
1133852006185	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133852006186	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1133852006187	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1133852006188	molybdopterin cofactor binding site [chemical binding]; other site
1133852006189	substrate binding site [chemical binding]; other site
1133852006190	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1133852006191	molybdopterin cofactor binding site; other site
1133852006192	tRNA (mo5U34)-methyltransferase; Region: TIGR00452
1133852006193	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006194	S-adenosylmethionine binding site [chemical binding]; other site
1133852006195	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006196	S-adenosylmethionine binding site [chemical binding]; other site
1133852006197	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1133852006198	hypothetical protein; Provisional; Region: PRK10302
1133852006199	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1133852006200	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1133852006201	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133852006202	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1133852006203	Int/Topo IB signature motif; other site
1133852006204	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1133852006205	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133852006206	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133852006207	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133852006208	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133852006209	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
1133852006210	Uncharacterized conserved protein (DUF2303); Region: DUF2303; cl02338
1133852006211	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133852006212	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852006213	non-specific DNA binding site [nucleotide binding]; other site
1133852006214	salt bridge; other site
1133852006215	sequence-specific DNA binding site [nucleotide binding]; other site
1133852006216	Predicted transcriptional regulator [Transcription]; Region: COG2932
1133852006217	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852006218	Catalytic site [active]
1133852006219	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852006220	non-specific DNA binding site [nucleotide binding]; other site
1133852006221	salt bridge; other site
1133852006222	sequence-specific DNA binding site [nucleotide binding]; other site
1133852006223	Ash protein family; Region: Phage_ASH; pfam10554
1133852006224	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1133852006225	Helix-turn-helix domain; Region: HTH_36; pfam13730
1133852006226	PerC transcriptional activator; Region: PerC; pfam06069
1133852006227	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1133852006228	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1133852006229	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
1133852006230	KilA-N domain; Region: KilA-N; pfam04383
1133852006231	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1133852006232	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1133852006233	active site
1133852006234	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133852006235	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1133852006236	EAP30/Vps36 family; Region: EAP30; pfam04157
1133852006237	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006238	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133852006239	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133852006240	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133852006241	Lysis protein S; Region: Lysis_S; pfam04971
1133852006242	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
1133852006243	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133852006244	catalytic residues [active]
1133852006245	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
1133852006246	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1133852006247	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1133852006248	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133852006249	gpW; Region: gpW; pfam02831
1133852006250	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1133852006251	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1133852006252	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133852006253	tandem repeat interface [polypeptide binding]; other site
1133852006254	oligomer interface [polypeptide binding]; other site
1133852006255	active site residues [active]
1133852006256	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133852006257	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133852006258	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133852006259	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133852006260	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133852006261	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133852006262	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133852006263	Phage tail protein; Region: Phage_tail_3; pfam08813
1133852006264	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133852006265	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1133852006266	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
1133852006267	Phage-related minor tail protein [Function unknown]; Region: COG5281
1133852006268	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133852006269	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; cl19901
1133852006270	Phage-related protein [Function unknown]; Region: COG4718
1133852006271	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133852006272	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133852006273	MPN+ (JAMM) motif; other site
1133852006274	Zinc-binding site [ion binding]; other site
1133852006275	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133852006276	NlpC/P60 family; Region: NLPC_P60; cl17555
1133852006277	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133852006278	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133852006279	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133852006280	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1133852006281	Interdomain contacts; other site
1133852006282	Cytokine receptor motif; other site
1133852006283	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133852006284	Fibronectin type III protein; Region: DUF3672; pfam12421
1133852006285	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133852006286	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133852006287	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852006288	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852006289	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852006290	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
1133852006291	DinI-like family; Region: DinI; pfam06183
1133852006292	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1133852006293	catalytic triad [active]
1133852006294	conserved cis-peptide bond; other site
1133852006295	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1133852006296	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1133852006297	dimer interface [polypeptide binding]; other site
1133852006298	anticodon binding site; other site
1133852006299	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1133852006300	homodimer interface [polypeptide binding]; other site
1133852006301	motif 1; other site
1133852006302	active site
1133852006303	motif 2; other site
1133852006304	GAD domain; Region: GAD; pfam02938
1133852006305	motif 3; other site
1133852006306	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1133852006307	nudix motif; other site
1133852006308	hypothetical protein; Validated; Region: PRK00110
1133852006309	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1133852006310	active site
1133852006311	putative DNA-binding cleft [nucleotide binding]; other site
1133852006312	dimer interface [polypeptide binding]; other site
1133852006313	hypothetical protein; Provisional; Region: PRK11470
1133852006314	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1133852006315	RuvA N terminal domain; Region: RuvA_N; pfam01330
1133852006316	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
1133852006317	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1133852006318	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1133852006319	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852006320	Walker A motif; other site
1133852006321	ATP binding site [chemical binding]; other site
1133852006322	Walker B motif; other site
1133852006323	arginine finger; other site
1133852006324	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1133852006325	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852006326	ABC-ATPase subunit  interface; other site
1133852006327	dimer interface [polypeptide binding]; other site
1133852006328	putative PBP binding regions; other site
1133852006329	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1133852006330	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1133852006331	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1133852006332	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1133852006333	metal binding site [ion binding]; metal-binding site
1133852006334	putative peptidase; Provisional; Region: PRK11649
1133852006335	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1133852006336	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852006337	Peptidase family M23; Region: Peptidase_M23; pfam01551
1133852006338	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133852006339	putative acyl-acceptor binding pocket; other site
1133852006340	pyruvate kinase; Provisional; Region: PRK05826
1133852006341	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1133852006342	domain interfaces; other site
1133852006343	active site
1133852006344	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1133852006345	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133852006346	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133852006347	putative active site [active]
1133852006348	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1133852006349	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1133852006350	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1133852006351	phosphogluconate dehydratase; Validated; Region: PRK09054
1133852006352	Entner-Doudoroff aldolase; Region: eda; TIGR01182
1133852006353	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1133852006354	active site
1133852006355	intersubunit interface [polypeptide binding]; other site
1133852006356	catalytic residue [active]
1133852006357	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1133852006358	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133852006359	ATP-grasp domain; Region: ATP-grasp; pfam02222
1133852006360	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1133852006361	hypothetical protein; Provisional; Region: PRK13680
1133852006362	Protein of unknown function (DUF533); Region: DUF533; pfam04391
1133852006363	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1133852006364	putative metal binding site [ion binding]; other site
1133852006365	protease 2; Provisional; Region: PRK10115
1133852006366	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1133852006367	exodeoxyribonuclease X; Provisional; Region: PRK07983
1133852006368	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1133852006369	active site
1133852006370	catalytic site [active]
1133852006371	substrate binding site [chemical binding]; other site
1133852006372	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1133852006373	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1133852006374	hypothetical protein; Provisional; Region: PRK10301
1133852006375	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1133852006376	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1133852006377	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1133852006378	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1133852006379	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1133852006380	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1133852006381	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006382	S-adenosylmethionine binding site [chemical binding]; other site
1133852006383	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; cl19835
1133852006384	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1133852006385	mce related protein; Region: MCE; pfam02470
1133852006386	mce related protein; Region: MCE; pfam02470
1133852006387	mce related protein; Region: MCE; pfam02470
1133852006388	mce related protein; Region: MCE; pfam02470
1133852006389	mce related protein; Region: MCE; pfam02470
1133852006390	mce related protein; Region: MCE; pfam02470
1133852006391	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
1133852006392	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133852006393	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133852006394	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1133852006395	ProP expression regulator; Provisional; Region: PRK04950
1133852006396	putative RNA binding sites [nucleotide binding]; other site
1133852006397	carboxy-terminal protease; Provisional; Region: PRK11186
1133852006398	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1133852006399	protein binding site [polypeptide binding]; other site
1133852006400	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1133852006401	Catalytic dyad [active]
1133852006402	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1133852006403	heat shock protein HtpX; Provisional; Region: PRK05457
1133852006404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006405	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852006406	putative substrate translocation pore; other site
1133852006407	Predicted integral membrane protein [Function unknown]; Region: COG5521
1133852006408	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1133852006409	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852006410	dimerization interface [polypeptide binding]; other site
1133852006411	putative Zn2+ binding site [ion binding]; other site
1133852006412	putative DNA binding site [nucleotide binding]; other site
1133852006413	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133852006414	YobH-like protein; Region: YobH; pfam13996
1133852006415	PhoPQ regulatory protein; Provisional; Region: PRK10299
1133852006416	YebO-like protein; Region: YebO; pfam13974
1133852006417	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
1133852006418	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133852006419	DNA-binding site [nucleotide binding]; DNA binding site
1133852006420	RNA-binding motif; other site
1133852006421	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133852006422	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006423	S-adenosylmethionine binding site [chemical binding]; other site
1133852006424	hypothetical protein; Provisional; Region: PRK11469
1133852006425	Domain of unknown function DUF; Region: DUF204; pfam02659
1133852006426	Domain of unknown function DUF; Region: DUF204; pfam02659
1133852006427	hypothetical protein; Provisional; Region: PRK02913
1133852006428	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1133852006429	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1133852006430	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1133852006431	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1133852006432	active pocket/dimerization site; other site
1133852006433	active site
1133852006434	phosphorylation site [posttranslational modification]
1133852006435	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1133852006436	active site
1133852006437	phosphorylation site [posttranslational modification]
1133852006438	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1133852006439	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1133852006440	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133852006441	Transporter associated domain; Region: CorC_HlyC; smart01091
1133852006442	phage resistance protein; Provisional; Region: PRK10551
1133852006443	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133852006444	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852006445	L-serine deaminase; Provisional; Region: PRK15023
1133852006446	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1133852006447	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1133852006448	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1133852006449	putative active site [active]
1133852006450	putative CoA binding site [chemical binding]; other site
1133852006451	nudix motif; other site
1133852006452	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1133852006453	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1133852006454	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1133852006455	hypothetical protein; Provisional; Region: PRK05114
1133852006456	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1133852006457	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1133852006458	homotrimer interaction site [polypeptide binding]; other site
1133852006459	putative active site [active]
1133852006460	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1133852006461	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cd09708
1133852006462	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1133852006463	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1133852006464	Glycoprotease family; Region: Peptidase_M22; pfam00814
1133852006465	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
1133852006466	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1133852006467	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1133852006468	acyl-activating enzyme (AAE) consensus motif; other site
1133852006469	putative AMP binding site [chemical binding]; other site
1133852006470	putative active site [active]
1133852006471	putative CoA binding site [chemical binding]; other site
1133852006472	ribonuclease D; Provisional; Region: PRK10829
1133852006473	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1133852006474	catalytic site [active]
1133852006475	putative active site [active]
1133852006476	putative substrate binding site [chemical binding]; other site
1133852006477	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1133852006478	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1133852006479	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1133852006480	FMN-binding pocket [chemical binding]; other site
1133852006481	flavin binding motif; other site
1133852006482	phosphate binding motif [ion binding]; other site
1133852006483	beta-alpha-beta structure motif; other site
1133852006484	NAD binding pocket [chemical binding]; other site
1133852006485	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852006486	catalytic loop [active]
1133852006487	iron binding site [ion binding]; other site
1133852006488	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1133852006489	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1133852006490	[2Fe-2S] cluster binding site [ion binding]; other site
1133852006491	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
1133852006492	putative alpha subunit interface [polypeptide binding]; other site
1133852006493	putative active site [active]
1133852006494	putative substrate binding site [chemical binding]; other site
1133852006495	Fe binding site [ion binding]; other site
1133852006496	putative transporter; Provisional; Region: PRK09950
1133852006497	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1133852006498	transcriptional activator TtdR; Provisional; Region: PRK09801
1133852006499	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852006500	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1133852006501	putative effector binding pocket; other site
1133852006502	putative dimerization interface [polypeptide binding]; other site
1133852006503	leucine export protein LeuE; Provisional; Region: PRK10958
1133852006504	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1133852006505	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1133852006506	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1133852006507	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1133852006508	Probable transposase; Region: OrfB_IS605; pfam01385
1133852006509	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1133852006510	hypothetical protein; Provisional; Region: PRK10457
1133852006511	hypothetical protein; Provisional; Region: PRK14760
1133852006512	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1133852006513	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852006514	metal binding site [ion binding]; metal-binding site
1133852006515	active site
1133852006516	I-site; other site
1133852006517	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1133852006518	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1133852006519	cyanate transporter; Region: CynX; TIGR00896
1133852006520	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006521	putative substrate translocation pore; other site
1133852006522	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852006523	Protein of unknown function (DUF441); Region: DUF441; cl01041
1133852006524	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1133852006525	putative deacylase active site [active]
1133852006526	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852006527	metal binding site [ion binding]; metal-binding site
1133852006528	active site
1133852006529	I-site; other site
1133852006530	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852006531	metal binding site [ion binding]; metal-binding site
1133852006532	active site
1133852006533	I-site; other site
1133852006534	Uncharacterized conserved protein [Function unknown]; Region: COG2718
1133852006535	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1133852006536	metal ion-dependent adhesion site (MIDAS); other site
1133852006537	PrkA family serine protein kinase; Provisional; Region: PRK15455
1133852006538	PrkA AAA domain; Region: AAA_PrkA; pfam08298
1133852006539	Walker A motif; other site
1133852006540	ATP binding site [chemical binding]; other site
1133852006541	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1133852006542	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1133852006543	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852006544	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852006545	active site
1133852006546	catalytic tetrad [active]
1133852006547	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1133852006548	active site
1133852006549	phosphate binding residues; other site
1133852006550	catalytic residues [active]
1133852006551	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1133852006552	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1133852006553	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1133852006554	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1133852006555	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1133852006556	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852006557	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
1133852006558	putative NAD(P) binding site [chemical binding]; other site
1133852006559	catalytic Zn binding site [ion binding]; other site
1133852006560	structural Zn binding site [ion binding]; other site
1133852006561	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006562	putative substrate translocation pore; other site
1133852006563	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1133852006564	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852006565	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1133852006566	inhibitor binding site; inhibition site
1133852006567	catalytic Zn binding site [ion binding]; other site
1133852006568	structural Zn binding site [ion binding]; other site
1133852006569	NADP binding site [chemical binding]; other site
1133852006570	tetramer interface [polypeptide binding]; other site
1133852006571	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1133852006572	intersubunit interface [polypeptide binding]; other site
1133852006573	active site
1133852006574	zinc binding site [ion binding]; other site
1133852006575	Na+ binding site [ion binding]; other site
1133852006576	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1133852006577	substrate binding site [chemical binding]; other site
1133852006578	ATP binding site [chemical binding]; other site
1133852006579	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852006580	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852006581	active site
1133852006582	catalytic tetrad [active]
1133852006583	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133852006584	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133852006585	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852006586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006587	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1133852006588	putative substrate translocation pore; other site
1133852006589	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1133852006590	catalytic triad [active]
1133852006591	metal binding site [ion binding]; metal-binding site
1133852006592	conserved cis-peptide bond; other site
1133852006593	cytoplasmic asparaginase I; Provisional; Region: ansA; PRK09461
1133852006594	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1133852006595	active site
1133852006596	homodimer interface [polypeptide binding]; other site
1133852006597	protease 4; Provisional; Region: PRK10949
1133852006598	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1133852006599	tandem repeat interface [polypeptide binding]; other site
1133852006600	oligomer interface [polypeptide binding]; other site
1133852006601	active site residues [active]
1133852006602	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1133852006603	tandem repeat interface [polypeptide binding]; other site
1133852006604	oligomer interface [polypeptide binding]; other site
1133852006605	active site residues [active]
1133852006606	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1133852006607	putative FMN binding site [chemical binding]; other site
1133852006608	selenophosphate synthetase; Provisional; Region: PRK00943
1133852006609	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1133852006610	dimerization interface [polypeptide binding]; other site
1133852006611	putative ATP binding site [chemical binding]; other site
1133852006612	DNA topoisomerase III; Provisional; Region: PRK07726
1133852006613	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1133852006614	active site
1133852006615	putative interdomain interaction site [polypeptide binding]; other site
1133852006616	putative metal-binding site [ion binding]; other site
1133852006617	putative nucleotide binding site [chemical binding]; other site
1133852006618	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1133852006619	domain I; other site
1133852006620	DNA binding groove [nucleotide binding]
1133852006621	phosphate binding site [ion binding]; other site
1133852006622	domain II; other site
1133852006623	domain III; other site
1133852006624	nucleotide binding site [chemical binding]; other site
1133852006625	catalytic site [active]
1133852006626	domain IV; other site
1133852006627	hypothetical protein; Provisional; Region: PRK11380
1133852006628	glutamate dehydrogenase; Provisional; Region: PRK09414
1133852006629	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
1133852006630	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1133852006631	NAD(P) binding site [chemical binding]; other site
1133852006632	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1133852006633	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1133852006634	active site
1133852006635	8-oxo-dGMP binding site [chemical binding]; other site
1133852006636	nudix motif; other site
1133852006637	metal binding site [ion binding]; metal-binding site
1133852006638	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1133852006639	Rhodanese Homology Domain; Region: RHOD; smart00450
1133852006640	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1133852006641	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1133852006642	active site residue [active]
1133852006643	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1133852006644	active site residue [active]
1133852006645	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
1133852006646	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852006647	Walker A/P-loop; other site
1133852006648	ATP binding site [chemical binding]; other site
1133852006649	Q-loop/lid; other site
1133852006650	ABC transporter signature motif; other site
1133852006651	Walker B; other site
1133852006652	D-loop; other site
1133852006653	H-loop/switch region; other site
1133852006654	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
1133852006655	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852006656	dimer interface [polypeptide binding]; other site
1133852006657	ABC-ATPase subunit interface; other site
1133852006658	putative PBP binding loops; other site
1133852006659	hypothetical protein; Provisional; Region: PRK11622
1133852006660	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1133852006661	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1133852006662	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1133852006663	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1133852006664	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1133852006665	putative catalytic site [active]
1133852006666	putative phosphate binding site [ion binding]; other site
1133852006667	active site
1133852006668	metal binding site A [ion binding]; metal-binding site
1133852006669	DNA binding site [nucleotide binding]
1133852006670	putative AP binding site [nucleotide binding]; other site
1133852006671	putative metal binding site B [ion binding]; other site
1133852006672	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1133852006673	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852006674	inhibitor-cofactor binding pocket; inhibition site
1133852006675	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852006676	catalytic residue [active]
1133852006677	arginine succinyltransferase; Provisional; Region: PRK10456
1133852006678	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1133852006679	NAD(P) binding site [chemical binding]; other site
1133852006680	catalytic residues [active]
1133852006681	succinylarginine dihydrolase; Provisional; Region: PRK13281
1133852006682	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1133852006683	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1133852006684	putative active site [active]
1133852006685	Zn binding site [ion binding]; other site
1133852006686	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1133852006687	dimer interface [polypeptide binding]; other site
1133852006688	hypothetical protein; Provisional; Region: PRK11396
1133852006689	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1133852006690	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1133852006691	GIY-YIG motif/motif A; other site
1133852006692	active site
1133852006693	catalytic site [active]
1133852006694	putative DNA binding site [nucleotide binding]; other site
1133852006695	metal binding site [ion binding]; metal-binding site
1133852006696	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852006697	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1133852006698	homodimer interface [polypeptide binding]; other site
1133852006699	NAD binding pocket [chemical binding]; other site
1133852006700	ATP binding pocket [chemical binding]; other site
1133852006701	Mg binding site [ion binding]; other site
1133852006702	active-site loop [active]
1133852006703	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1133852006704	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1133852006705	active site
1133852006706	P-loop; other site
1133852006707	phosphorylation site [posttranslational modification]
1133852006708	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1133852006709	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1133852006710	methionine cluster; other site
1133852006711	active site
1133852006712	phosphorylation site [posttranslational modification]
1133852006713	metal binding site [ion binding]; metal-binding site
1133852006714	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1133852006715	Cupin domain; Region: Cupin_2; cl17218
1133852006716	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852006717	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1133852006718	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1133852006719	NAD binding site [chemical binding]; other site
1133852006720	sugar binding site [chemical binding]; other site
1133852006721	divalent metal binding site [ion binding]; other site
1133852006722	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133852006723	dimer interface [polypeptide binding]; other site
1133852006724	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1133852006725	putative active site [active]
1133852006726	YdjC motif; other site
1133852006727	Mg binding site [ion binding]; other site
1133852006728	putative homodimer interface [polypeptide binding]; other site
1133852006729	hydroperoxidase II; Provisional; Region: katE; PRK11249
1133852006730	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1133852006731	tetramer interface [polypeptide binding]; other site
1133852006732	heme binding pocket [chemical binding]; other site
1133852006733	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1133852006734	domain interactions; other site
1133852006735	Cell division activator CedA; Region: CedA; pfam10729
1133852006736	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852006737	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852006738	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852006739	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133852006740	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1133852006741	inner membrane protein; Provisional; Region: PRK11648
1133852006742	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1133852006743	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1133852006744	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852006745	motif II; other site
1133852006746	YniB-like protein; Region: YniB; pfam14002
1133852006747	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3001
1133852006748	Phosphotransferase enzyme family; Region: APH; pfam01636
1133852006749	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1133852006750	active site
1133852006751	substrate binding site [chemical binding]; other site
1133852006752	ATP binding site [chemical binding]; other site
1133852006753	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1133852006754	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1133852006755	putative substrate binding site [chemical binding]; other site
1133852006756	putative ATP binding site [chemical binding]; other site
1133852006757	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1133852006758	potential frameshift: common BLAST hit: gi|218705219|ref|YP_002412738.1| putative ankyrin repeat regulatory protein
1133852006759	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1133852006760	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1133852006761	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1133852006762	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1133852006763	active site
1133852006764	dimer interface [polypeptide binding]; other site
1133852006765	motif 1; other site
1133852006766	motif 2; other site
1133852006767	motif 3; other site
1133852006768	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1133852006769	anticodon binding site; other site
1133852006770	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1133852006771	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1133852006772	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1133852006773	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1133852006774	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1133852006775	23S rRNA binding site [nucleotide binding]; other site
1133852006776	L21 binding site [polypeptide binding]; other site
1133852006777	L13 binding site [polypeptide binding]; other site
1133852006778	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1133852006779	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1133852006780	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1133852006781	dimer interface [polypeptide binding]; other site
1133852006782	motif 1; other site
1133852006783	active site
1133852006784	motif 2; other site
1133852006785	motif 3; other site
1133852006786	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1133852006787	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1133852006788	putative tRNA-binding site [nucleotide binding]; other site
1133852006789	B3/4 domain; Region: B3_4; pfam03483
1133852006790	tRNA synthetase B5 domain; Region: B5; smart00874
1133852006791	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1133852006792	dimer interface [polypeptide binding]; other site
1133852006793	motif 1; other site
1133852006794	motif 3; other site
1133852006795	motif 2; other site
1133852006796	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1133852006797	Alpha subunit of integration host factor (IHFA); Region: IHF_A; cd13835
1133852006798	DNA binding site [nucleotide binding]
1133852006799	dimer interface [polypeptide binding]; other site
1133852006800	Hok/gef family; Region: HOK_GEF; pfam01848
1133852006801	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1133852006802	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852006803	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852006804	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852006805	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133852006806	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1133852006807	tail protein; Provisional; Region: D; PHA02561
1133852006808	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
1133852006809	Phage tail tube protein FII; Region: Phage_tube; cl01390
1133852006810	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1133852006811	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1133852006812	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1133852006813	Phage protein U [General function prediction only]; Region: COG3499
1133852006814	PEHE domain; Region: PEHE; pfam15275
1133852006815	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
1133852006816	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1133852006817	trimer interface [polypeptide binding]; other site
1133852006818	active site
1133852006819	substrate binding site [chemical binding]; other site
1133852006820	CoA binding site [chemical binding]; other site
1133852006821	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133852006822	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1133852006823	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852006824	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852006825	Phage Tail Collar Domain; Region: Collar; pfam07484
1133852006826	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
1133852006827	Baseplate J-like protein; Region: Baseplate_J; cl01294
1133852006828	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1133852006829	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
1133852006830	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
1133852006831	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1133852006832	Domain of unknown function (DUF1737); Region: DUF1737; cl10503
1133852006833	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133852006834	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
1133852006835	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1133852006836	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1133852006837	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1133852006838	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1133852006839	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1133852006840	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
1133852006841	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
1133852006842	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1133852006843	terminase ATPase subunit; Provisional; Region: P; PHA02535
1133852006844	Phage portal protein; Region: Phage_portal; cl19194
1133852006845	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
1133852006846	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1133852006847	Mg binding site [ion binding]; other site
1133852006848	nucleotide binding site [chemical binding]; other site
1133852006849	putative protofilament interface [polypeptide binding]; other site
1133852006850	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1133852006851	CRISPR/Cas system-associated RAMP superfamily protein Csx10; Region: Csx10; cl17558
1133852006852	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133852006853	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133852006854	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1133852006855	putative DNA binding site [nucleotide binding]; other site
1133852006856	putative Zn2+ binding site [ion binding]; other site
1133852006857	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852006858	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133852006859	non-specific DNA binding site [nucleotide binding]; other site
1133852006860	salt bridge; other site
1133852006861	sequence-specific DNA binding site [nucleotide binding]; other site
1133852006862	integrase; Provisional; Region: int; PHA02601
1133852006863	AP2-like DNA-binding integrase domain; Region: Integrase_AP2; pfam14657
1133852006864	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1133852006865	active site
1133852006866	DNA binding site [nucleotide binding]
1133852006867	Int/Topo IB signature motif; other site
1133852006868	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852006869	ABC-ATPase subunit  interface; other site
1133852006870	dimer interface [polypeptide binding]; other site
1133852006871	putative PBP binding regions; other site
1133852006872	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1133852006873	catalytic residues [active]
1133852006874	dimer interface [polypeptide binding]; other site
1133852006875	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
1133852006876	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133852006877	Walker A/P-loop; other site
1133852006878	ATP binding site [chemical binding]; other site
1133852006879	Q-loop/lid; other site
1133852006880	ABC transporter signature motif; other site
1133852006881	Walker B; other site
1133852006882	D-loop; other site
1133852006883	H-loop/switch region; other site
1133852006884	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133852006885	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1133852006886	hypothetical protein; Validated; Region: PRK00029
1133852006887	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
1133852006888	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1133852006889	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1133852006890	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1133852006891	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1133852006892	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133852006893	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133852006894	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1133852006895	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1133852006896	acyl-activating enzyme (AAE) consensus motif; other site
1133852006897	putative AMP binding site [chemical binding]; other site
1133852006898	putative active site [active]
1133852006899	putative CoA binding site [chemical binding]; other site
1133852006900	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1133852006901	oxidoreductase; Provisional; Region: PRK10015
1133852006902	putative oxidoreductase FixC; Provisional; Region: PRK10157
1133852006903	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1133852006904	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1133852006905	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1133852006906	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1133852006907	Ligand binding site [chemical binding]; other site
1133852006908	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133852006909	Cupin domain; Region: Cupin_2; pfam07883
1133852006910	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
1133852006911	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852006912	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1133852006913	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1133852006914	active site
1133852006915	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1133852006916	Coenzyme A transferase; Region: CoA_trans; smart00882
1133852006917	Coenzyme A transferase; Region: CoA_trans; cl17247
1133852006918	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1133852006919	active site
1133852006920	catalytic residue [active]
1133852006921	dimer interface [polypeptide binding]; other site
1133852006922	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1133852006923	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1133852006924	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1133852006925	shikimate binding site; other site
1133852006926	NAD(P) binding site [chemical binding]; other site
1133852006927	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006928	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852006929	putative substrate translocation pore; other site
1133852006930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006931	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852006932	putative substrate translocation pore; other site
1133852006933	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1133852006934	putative inner membrane protein; Provisional; Region: PRK10983
1133852006935	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1133852006936	FAD binding domain; Region: FAD_binding_4; pfam01565
1133852006937	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
1133852006938	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1133852006939	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1133852006940	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133852006941	CoenzymeA binding site [chemical binding]; other site
1133852006942	subunit interaction site [polypeptide binding]; other site
1133852006943	PHB binding site; other site
1133852006944	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1133852006945	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1133852006946	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1133852006947	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1133852006948	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1133852006949	Walker A/P-loop; other site
1133852006950	ATP binding site [chemical binding]; other site
1133852006951	Q-loop/lid; other site
1133852006952	ABC transporter signature motif; other site
1133852006953	Walker B; other site
1133852006954	D-loop; other site
1133852006955	H-loop/switch region; other site
1133852006956	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1133852006957	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1133852006958	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1133852006959	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852006960	catalytic residue [active]
1133852006961	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1133852006962	L,D-transpeptidase; Provisional; Region: PRK10260
1133852006963	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852006964	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133852006965	murein lipoprotein; Provisional; Region: PRK15396
1133852006966	pyruvate kinase; Provisional; Region: PRK09206
1133852006967	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1133852006968	domain interfaces; other site
1133852006969	active site
1133852006970	hypothetical protein; Provisional; Region: PRK10292
1133852006971	hypothetical protein; Provisional; Region: PRK09898
1133852006972	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852006973	putative oxidoreductase; Provisional; Region: PRK09849
1133852006974	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
1133852006975	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
1133852006976	hypothetical protein; Provisional; Region: PRK09947
1133852006977	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1133852006978	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852006979	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1133852006980	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1133852006981	hypothetical protein; Provisional; Region: PRK09946
1133852006982	hypothetical protein; Provisional; Region: PRK09897
1133852006983	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
1133852006984	putative monooxygenase; Provisional; Region: PRK11118
1133852006985	hypothetical protein; Provisional; Region: PRK09945
1133852006986	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1133852006987	multidrug efflux protein; Reviewed; Region: PRK01766
1133852006988	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1133852006989	cation binding site [ion binding]; other site
1133852006990	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1133852006991	Lumazine binding domain; Region: Lum_binding; pfam00677
1133852006992	Lumazine binding domain; Region: Lum_binding; pfam00677
1133852006993	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1133852006994	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1133852006995	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852006996	S-adenosylmethionine binding site [chemical binding]; other site
1133852006997	putative transporter; Provisional; Region: PRK11043
1133852006998	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852006999	putative substrate translocation pore; other site
1133852007000	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1133852007001	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852007002	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852007003	dimerization interface [polypeptide binding]; other site
1133852007004	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1133852007005	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852007006	DNA binding site [nucleotide binding]
1133852007007	domain linker motif; other site
1133852007008	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1133852007009	dimerization interface [polypeptide binding]; other site
1133852007010	ligand binding site [chemical binding]; other site
1133852007011	hypothetical protein; Provisional; Region: PRK14756
1133852007012	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1133852007013	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852007014	putative substrate translocation pore; other site
1133852007015	superoxide dismutase; Provisional; Region: PRK10543
1133852007016	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1133852007017	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1133852007018	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133852007019	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133852007020	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1133852007021	putative GSH binding site [chemical binding]; other site
1133852007022	catalytic residues [active]
1133852007023	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852007024	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
1133852007025	ATP binding site [chemical binding]; other site
1133852007026	putative Mg++ binding site [ion binding]; other site
1133852007027	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852007028	nucleotide binding region [chemical binding]; other site
1133852007029	ATP-binding site [chemical binding]; other site
1133852007030	DEAD/H associated; Region: DEAD_assoc; pfam08494
1133852007031	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1133852007032	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1133852007033	dimer interface [polypeptide binding]; other site
1133852007034	catalytic site [active]
1133852007035	putative active site [active]
1133852007036	putative substrate binding site [chemical binding]; other site
1133852007037	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1133852007038	dimer interface [polypeptide binding]; other site
1133852007039	active site
1133852007040	metal binding site [ion binding]; metal-binding site
1133852007041	glutathione binding site [chemical binding]; other site
1133852007042	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1133852007043	FMN binding site [chemical binding]; other site
1133852007044	active site
1133852007045	substrate binding site [chemical binding]; other site
1133852007046	catalytic residue [active]
1133852007047	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133852007048	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852007049	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1133852007050	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852007051	active site
1133852007052	catalytic tetrad [active]
1133852007053	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1133852007054	E-class dimer interface [polypeptide binding]; other site
1133852007055	P-class dimer interface [polypeptide binding]; other site
1133852007056	active site
1133852007057	Cu2+ binding site [ion binding]; other site
1133852007058	Zn2+ binding site [ion binding]; other site
1133852007059	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1133852007060	Fusaric acid resistance protein-like; Region: FUSC_2; cl19401
1133852007061	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1133852007062	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852007063	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852007064	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1133852007065	transcriptional regulator SlyA; Provisional; Region: PRK03573
1133852007066	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133852007067	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1133852007068	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
1133852007069	lysozyme inhibitor; Provisional; Region: PRK11372
1133852007070	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1133852007071	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1133852007072	Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; Region: PNPOx_C; pfam10590
1133852007073	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1133852007074	Protein of unknown function (DUF2859); Region: DUF2859; cl12633
1133852007075	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1133852007076	active site
1133852007077	HIGH motif; other site
1133852007078	dimer interface [polypeptide binding]; other site
1133852007079	KMSKS motif; other site
1133852007080	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852007081	RNA binding surface [nucleotide binding]; other site
1133852007082	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1133852007083	dimer interface [polypeptide binding]; other site
1133852007084	pyridoxal binding site [chemical binding]; other site
1133852007085	ATP binding site [chemical binding]; other site
1133852007086	glutathionine S-transferase; Provisional; Region: PRK10542
1133852007087	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1133852007088	C-terminal domain interface [polypeptide binding]; other site
1133852007089	GSH binding site (G-site) [chemical binding]; other site
1133852007090	dimer interface [polypeptide binding]; other site
1133852007091	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1133852007092	N-terminal domain interface [polypeptide binding]; other site
1133852007093	dimer interface [polypeptide binding]; other site
1133852007094	substrate binding pocket (H-site) [chemical binding]; other site
1133852007095	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133852007096	putative tripeptide transporter permease; Reviewed; Region: tppB; PRK09584
1133852007097	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852007098	putative substrate translocation pore; other site
1133852007099	endonuclease III; Provisional; Region: PRK10702
1133852007100	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1133852007101	minor groove reading motif; other site
1133852007102	helix-hairpin-helix signature motif; other site
1133852007103	substrate binding pocket [chemical binding]; other site
1133852007104	active site
1133852007105	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1133852007106	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1133852007107	electron transport complex protein RnfG; Validated; Region: PRK01908
1133852007108	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1133852007109	electron transport complex protein RnfC; Provisional; Region: PRK05035
1133852007110	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1133852007111	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1133852007112	SLBB domain; Region: SLBB; pfam10531
1133852007113	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1133852007114	electron transport complex protein RnfB; Provisional; Region: PRK05113
1133852007115	Putative Fe-S cluster; Region: FeS; pfam04060
1133852007116	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852007117	electron transport complex protein RsxA; Provisional; Region: PRK05151
1133852007118	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1133852007119	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1133852007120	putative oxidoreductase; Provisional; Region: PRK11579
1133852007121	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133852007122	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133852007123	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1133852007124	active site
1133852007125	purine riboside binding site [chemical binding]; other site
1133852007126	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
1133852007127	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852007128	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852007129	homodimer interface [polypeptide binding]; other site
1133852007130	catalytic residue [active]
1133852007131	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1133852007132	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1133852007133	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852007134	active site turn [active]
1133852007135	phosphorylation site [posttranslational modification]
1133852007136	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1133852007137	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852007138	DNA binding site [nucleotide binding]
1133852007139	domain linker motif; other site
1133852007140	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
1133852007141	putative dimerization interface [polypeptide binding]; other site
1133852007142	putative ligand binding site [chemical binding]; other site
1133852007143	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
1133852007144	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
1133852007145	NAD binding site [chemical binding]; other site
1133852007146	substrate binding site [chemical binding]; other site
1133852007147	homotetramer interface [polypeptide binding]; other site
1133852007148	homodimer interface [polypeptide binding]; other site
1133852007149	active site
1133852007150	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133852007151	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852007152	beta-D-glucuronidase; Provisional; Region: PRK10150
1133852007153	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1133852007154	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1133852007155	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1133852007156	glucuronide transporter; Provisional; Region: PRK09848
1133852007157	putative symporter YagG; Provisional; Region: PRK09669; cl15392
1133852007158	putative outer membrane porin protein; Provisional; Region: PRK11379
1133852007159	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1133852007160	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1133852007161	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1133852007162	fumarate hydratase; Provisional; Region: PRK15389
1133852007163	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1133852007164	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1133852007165	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1133852007166	Class II fumarases; Region: Fumarase_classII; cd01362
1133852007167	active site
1133852007168	tetramer interface [polypeptide binding]; other site
1133852007169	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1133852007170	sensor protein RstB; Provisional; Region: PRK10604
1133852007171	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852007172	dimerization interface [polypeptide binding]; other site
1133852007173	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852007174	dimer interface [polypeptide binding]; other site
1133852007175	phosphorylation site [posttranslational modification]
1133852007176	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852007177	ATP binding site [chemical binding]; other site
1133852007178	Mg2+ binding site [ion binding]; other site
1133852007179	G-X-G motif; other site
1133852007180	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1133852007181	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852007182	active site
1133852007183	phosphorylation site [posttranslational modification]
1133852007184	intermolecular recognition site; other site
1133852007185	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852007186	DNA binding site [nucleotide binding]
1133852007187	GlpM protein; Region: GlpM; pfam06942
1133852007188	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
1133852007189	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1133852007190	NADP binding site [chemical binding]; other site
1133852007191	substrate binding pocket [chemical binding]; other site
1133852007192	active site
1133852007193	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1133852007194	Spore germination protein; Region: Spore_permease; cl17796
1133852007195	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852007196	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852007197	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852007198	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1133852007199	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1133852007200	ligand binding site [chemical binding]; other site
1133852007201	homodimer interface [polypeptide binding]; other site
1133852007202	NAD(P) binding site [chemical binding]; other site
1133852007203	trimer interface B [polypeptide binding]; other site
1133852007204	trimer interface A [polypeptide binding]; other site
1133852007205	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1133852007206	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1133852007207	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1133852007208	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1133852007209	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1133852007210	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1133852007211	hypothetical protein; Provisional; Region: PRK14758
1133852007212	acid shock protein precursor; Provisional; Region: PRK03577
1133852007213	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1133852007214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852007215	putative substrate translocation pore; other site
1133852007216	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1133852007217	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852007218	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1133852007219	dimerization interface [polypeptide binding]; other site
1133852007220	substrate binding pocket [chemical binding]; other site
1133852007221	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1133852007222	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133852007223	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852007224	nucleotide binding site [chemical binding]; other site
1133852007225	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1133852007226	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1133852007227	AAA domain; Region: AAA_26; pfam13500
1133852007228	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1133852007229	Cl- selectivity filter; other site
1133852007230	Cl- binding residues [ion binding]; other site
1133852007231	pore gating glutamate residue; other site
1133852007232	dimer interface [polypeptide binding]; other site
1133852007233	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1133852007234	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1133852007235	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852007236	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1133852007237	Ferredoxin [Energy production and conversion]; Region: COG1146
1133852007238	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133852007239	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
1133852007240	Int/Topo IB signature motif; other site
1133852007241	Helix-turn-helix domain; Region: HTH_17; pfam12728
1133852007242	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133852007243	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1133852007244	phage recombination protein Bet; Region: bet_lambda; TIGR01913
1133852007245	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
1133852007246	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1133852007247	Domain of unknown function DUF1828; Region: DUF1828; pfam08861
1133852007248	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852007249	non-specific DNA binding site [nucleotide binding]; other site
1133852007250	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1133852007251	salt bridge; other site
1133852007252	sequence-specific DNA binding site [nucleotide binding]; other site
1133852007253	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852007254	Catalytic site [active]
1133852007255	Cro; Region: Cro; pfam09048
1133852007256	Bacteriophage CII protein; Region: Phage_CII; pfam05269
1133852007257	primosomal protein DnaI; Provisional; Region: PRK02854
1133852007258	putative replication protein; Provisional; Region: PRK12377
1133852007259	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852007260	Walker A motif; other site
1133852007261	ATP binding site [chemical binding]; other site
1133852007262	Walker B motif; other site
1133852007263	arginine finger; other site
1133852007264	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
1133852007265	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1133852007266	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133852007267	Hok/gef family; Region: HOK_GEF; pfam01848
1133852007268	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1133852007269	Predicted transcriptional regulator [Transcription]; Region: COG2944
1133852007270	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852007271	non-specific DNA binding site [nucleotide binding]; other site
1133852007272	salt bridge; other site
1133852007273	sequence-specific DNA binding site [nucleotide binding]; other site
1133852007274	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1133852007275	ORF6N domain; Region: ORF6N; pfam10543
1133852007276	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1133852007277	NinB protein; Region: NinB; pfam05772
1133852007278	NINE Protein; Region: NinE; pfam05322
1133852007279	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1133852007280	Endodeoxyribonuclease RusA; Region: RusA; cl01885
1133852007281	Phage NinH protein; Region: Phage_NinH; pfam06322
1133852007282	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133852007283	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133852007284	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133852007285	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
1133852007286	Protein of unknown function (DUF826); Region: DUF826; pfam05696
1133852007287	Lysis protein S; Region: Lysis_S; pfam04971
1133852007288	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133852007289	catalytic residues [active]
1133852007290	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
1133852007291	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1133852007292	catalytic core [active]
1133852007293	large terminase protein; Provisional; Region: 17; PHA02533
1133852007294	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
1133852007295	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133852007296	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852007297	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852007298	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852007299	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852007300	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1133852007301	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133852007302	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133852007303	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133852007304	Hok/gef family; Region: HOK_GEF; pfam01848
1133852007305	EBNA-3B; Provisional; Region: PHA03378
1133852007306	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133852007307	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133852007308	DksA-like zinc finger domain containing protein; Region: PHA00080
1133852007309	Phage anti-repressor protein [Transcription]; Region: COG3561
1133852007310	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1133852007311	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1133852007312	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1133852007313	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1133852007314	putative [Fe4-S4] binding site [ion binding]; other site
1133852007315	putative molybdopterin cofactor binding site [chemical binding]; other site
1133852007316	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1133852007317	putative molybdopterin cofactor binding site; other site
1133852007318	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1133852007319	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1133852007320	putative [Fe4-S4] binding site [ion binding]; other site
1133852007321	putative molybdopterin cofactor binding site [chemical binding]; other site
1133852007322	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1133852007323	putative molybdopterin cofactor binding site; other site
1133852007324	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1133852007325	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1133852007326	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1133852007327	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852007328	Coenzyme A binding pocket [chemical binding]; other site
1133852007329	hypothetical protein; Provisional; Region: PRK13659
1133852007330	hypothetical protein; Provisional; Region: PRK02237
1133852007331	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1133852007332	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1133852007333	putative active site pocket [active]
1133852007334	putative metal binding site [ion binding]; other site
1133852007335	putative oxidoreductase; Provisional; Region: PRK10083
1133852007336	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1133852007337	putative NAD(P) binding site [chemical binding]; other site
1133852007338	catalytic Zn binding site [ion binding]; other site
1133852007339	structural Zn binding site [ion binding]; other site
1133852007340	metabolite-proton symporter; Region: 2A0106; TIGR00883
1133852007341	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852007342	putative substrate translocation pore; other site
1133852007343	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1133852007344	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133852007345	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133852007346	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1133852007347	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1133852007348	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852007349	DNA-binding site [nucleotide binding]; DNA binding site
1133852007350	FCD domain; Region: FCD; pfam07729
1133852007351	malonic semialdehyde reductase; Provisional; Region: PRK10538
1133852007352	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1133852007353	putative NAD(P) binding site [chemical binding]; other site
1133852007354	homodimer interface [polypeptide binding]; other site
1133852007355	homotetramer interface [polypeptide binding]; other site
1133852007356	active site
1133852007357	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
1133852007358	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1133852007359	active site
1133852007360	Zn binding site [ion binding]; other site
1133852007361	hypothetical protein; Validated; Region: PRK03657
1133852007362	hypothetical protein; Provisional; Region: PRK10053
1133852007363	diguanylate cyclase; Provisional; Region: PRK09894
1133852007364	Chemoreceptor zinc-binding domain; Region: CZB; pfam13682
1133852007365	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852007366	metal binding site [ion binding]; metal-binding site
1133852007367	active site
1133852007368	I-site; other site
1133852007369	putative transporter; Provisional; Region: PRK10054
1133852007370	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852007371	putative substrate translocation pore; other site
1133852007372	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1133852007373	EamA-like transporter family; Region: EamA; pfam00892
1133852007374	EamA-like transporter family; Region: EamA; pfam00892
1133852007375	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1133852007376	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852007377	DNA-binding site [nucleotide binding]; DNA binding site
1133852007378	UTRA domain; Region: UTRA; pfam07702
1133852007379	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1133852007380	active site
1133852007381	P-loop; other site
1133852007382	phosphorylation site [posttranslational modification]
1133852007383	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1133852007384	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1133852007385	active site
1133852007386	methionine cluster; other site
1133852007387	phosphorylation site [posttranslational modification]
1133852007388	metal binding site [ion binding]; metal-binding site
1133852007389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1133852007390	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1133852007391	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1133852007392	trimer interface; other site
1133852007393	maltoporin; Provisional; Region: lamB; PRK09360
1133852007394	sugar binding site [chemical binding]; other site
1133852007395	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
1133852007396	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
1133852007397	MarB protein; Region: MarB; pfam13999
1133852007398	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1133852007399	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852007400	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852007401	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1133852007402	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1133852007403	inner membrane protein; Provisional; Region: PRK10995
1133852007404	putative arabinose transporter; Provisional; Region: PRK03545
1133852007405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852007406	putative substrate translocation pore; other site
1133852007407	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852007408	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852007409	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1133852007410	putative dimerization interface [polypeptide binding]; other site
1133852007411	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1133852007412	NAD(P) binding site [chemical binding]; other site
1133852007413	catalytic residues [active]
1133852007414	glutaminase; Provisional; Region: PRK00971
1133852007415	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1133852007416	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852007417	metal binding site [ion binding]; metal-binding site
1133852007418	active site
1133852007419	I-site; other site
1133852007420	altronate oxidoreductase; Provisional; Region: PRK03643
1133852007421	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133852007422	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133852007423	Predicted membrane protein [Function unknown]; Region: COG3781
1133852007424	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
1133852007425	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852007426	S-adenosylmethionine binding site [chemical binding]; other site
1133852007427	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1133852007428	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1133852007429	putative active site; other site
1133852007430	catalytic residue [active]
1133852007431	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1133852007432	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1133852007433	ligand binding site [chemical binding]; other site
1133852007434	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852007435	TM-ABC transporter signature motif; other site
1133852007436	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852007437	TM-ABC transporter signature motif; other site
1133852007438	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1133852007439	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852007440	Walker A/P-loop; other site
1133852007441	ATP binding site [chemical binding]; other site
1133852007442	Q-loop/lid; other site
1133852007443	ABC transporter signature motif; other site
1133852007444	Walker B; other site
1133852007445	D-loop; other site
1133852007446	H-loop/switch region; other site
1133852007447	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852007448	transcriptional regulator LsrR; Provisional; Region: PRK15418
1133852007449	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1133852007450	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1133852007451	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1133852007452	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1133852007453	putative N- and C-terminal domain interface [polypeptide binding]; other site
1133852007454	putative active site [active]
1133852007455	putative MgATP binding site [chemical binding]; other site
1133852007456	catalytic site [active]
1133852007457	metal binding site [ion binding]; metal-binding site
1133852007458	putative carbohydrate binding site [chemical binding]; other site
1133852007459	putative lipoprotein; Provisional; Region: PRK09707
1133852007460	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852007461	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852007462	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133852007463	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852007464	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133852007465	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852007466	non-specific DNA binding site [nucleotide binding]; other site
1133852007467	salt bridge; other site
1133852007468	sequence-specific DNA binding site [nucleotide binding]; other site
1133852007469	HipA N-terminal domain; Region: couple_hipA; TIGR03071
1133852007470	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1133852007471	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1133852007472	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1133852007473	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133852007474	Fimbrial protein; Region: Fimbrial; cl01416
1133852007475	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1133852007476	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852007477	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852007478	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133852007479	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852007480	Outer membrane usher protein; Region: Usher; pfam00577
1133852007481	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852007482	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133852007483	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133852007484	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
1133852007485	mannosyl binding site [chemical binding]; other site
1133852007486	Fimbrial protein; Region: Fimbrial; cl01416
1133852007487	putative oxidoreductase; Provisional; Region: PRK09939
1133852007488	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1133852007489	putative molybdopterin cofactor binding site [chemical binding]; other site
1133852007490	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1133852007491	putative molybdopterin cofactor binding site; other site
1133852007492	transcriptional regulator YdeO; Provisional; Region: PRK09940
1133852007493	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852007494	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852007495	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1133852007496	Sulfatase; Region: Sulfatase; pfam00884
1133852007497	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1133852007498	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852007499	FeS/SAM binding site; other site
1133852007500	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1133852007501	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1133852007502	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1133852007503	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1133852007504	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1133852007505	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1133852007506	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1133852007507	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1133852007508	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133852007509	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1133852007510	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1133852007511	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1133852007512	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852007513	catalytic residue [active]
1133852007514	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
1133852007515	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1133852007516	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
1133852007517	heme-binding site [chemical binding]; other site
1133852007518	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852007519	metal binding site [ion binding]; metal-binding site
1133852007520	active site
1133852007521	I-site; other site
1133852007522	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
1133852007523	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852007524	putative active site [active]
1133852007525	heme pocket [chemical binding]; other site
1133852007526	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852007527	putative active site [active]
1133852007528	heme pocket [chemical binding]; other site
1133852007529	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852007530	metal binding site [ion binding]; metal-binding site
1133852007531	active site
1133852007532	I-site; other site
1133852007533	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852007534	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
1133852007535	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1133852007536	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1133852007537	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1133852007538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852007539	dimer interface [polypeptide binding]; other site
1133852007540	conserved gate region; other site
1133852007541	putative PBP binding loops; other site
1133852007542	ABC-ATPase subunit interface; other site
1133852007543	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
1133852007544	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133852007545	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852007546	dimer interface [polypeptide binding]; other site
1133852007547	conserved gate region; other site
1133852007548	putative PBP binding loops; other site
1133852007549	ABC-ATPase subunit interface; other site
1133852007550	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1133852007551	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852007552	Walker A/P-loop; other site
1133852007553	ATP binding site [chemical binding]; other site
1133852007554	Q-loop/lid; other site
1133852007555	ABC transporter signature motif; other site
1133852007556	Walker B; other site
1133852007557	D-loop; other site
1133852007558	H-loop/switch region; other site
1133852007559	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852007560	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1133852007561	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852007562	Walker A/P-loop; other site
1133852007563	ATP binding site [chemical binding]; other site
1133852007564	Q-loop/lid; other site
1133852007565	ABC transporter signature motif; other site
1133852007566	Walker B; other site
1133852007567	D-loop; other site
1133852007568	H-loop/switch region; other site
1133852007569	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1133852007570	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1133852007571	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
1133852007572	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1133852007573	malate dehydrogenase; Provisional; Region: PRK13529
1133852007574	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1133852007575	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1133852007576	NAD(P) binding site [chemical binding]; other site
1133852007577	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1133852007578	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1133852007579	NAD binding site [chemical binding]; other site
1133852007580	substrate binding site [chemical binding]; other site
1133852007581	catalytic Zn binding site [ion binding]; other site
1133852007582	tetramer interface [polypeptide binding]; other site
1133852007583	structural Zn binding site [ion binding]; other site
1133852007584	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852007585	non-specific DNA binding site [nucleotide binding]; other site
1133852007586	salt bridge; other site
1133852007587	sequence-specific DNA binding site [nucleotide binding]; other site
1133852007588	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1133852007589	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1133852007590	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852007591	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1133852007592	potential frameshift: common BLAST hit: gi|260867914|ref|YP_003234316.1| formate dehydrogenase-N subunit alpha, nitrate-inducible
1133852007593	aromatic amino acid exporter; Provisional; Region: PRK11689
1133852007594	EamA-like transporter family; Region: EamA; pfam00892
1133852007595	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1133852007596	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1133852007597	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1133852007598	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1133852007599	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1133852007600	Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710
1133852007601	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1133852007602	[4Fe-4S] binding site [ion binding]; other site
1133852007603	molybdopterin cofactor binding site [chemical binding]; other site
1133852007604	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1133852007605	molybdopterin cofactor binding site; other site
1133852007606	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1133852007607	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852007608	Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711
1133852007609	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1133852007610	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1133852007611	hypothetical protein; Provisional; Region: PRK10281
1133852007612	phenazine biosynthesis protein PhzF family; Region: PhzF_family; TIGR00654
1133852007613	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1133852007614	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1133852007615	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
1133852007616	active site 1 [active]
1133852007617	dimer interface [polypeptide binding]; other site
1133852007618	hexamer interface [polypeptide binding]; other site
1133852007619	active site 2 [active]
1133852007620	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133852007621	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852007622	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133852007623	PAAR motif; Region: PAAR_motif; cl15808
1133852007624	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852007625	RHS Repeat; Region: RHS_repeat; pfam05593
1133852007626	RHS Repeat; Region: RHS_repeat; pfam05593
1133852007627	RHS Repeat; Region: RHS_repeat; pfam05593
1133852007628	RHS Repeat; Region: RHS_repeat; pfam05593
1133852007629	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852007630	RHS Repeat; Region: RHS_repeat; pfam05593
1133852007631	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1133852007632	RHS Repeat; Region: RHS_repeat; pfam05593
1133852007633	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1133852007634	RHS protein; Region: RHS; pfam03527
1133852007635	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852007636	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133852007637	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133852007638	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133852007639	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1133852007640	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1133852007641	C-terminal domain interface [polypeptide binding]; other site
1133852007642	GSH binding site (G-site) [chemical binding]; other site
1133852007643	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1133852007644	dimer interface [polypeptide binding]; other site
1133852007645	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1133852007646	dimer interface [polypeptide binding]; other site
1133852007647	N-terminal domain interface [polypeptide binding]; other site
1133852007648	substrate binding pocket (H-site) [chemical binding]; other site
1133852007649	L-asparagine permease; Provisional; Region: PRK15049
1133852007650	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852007651	PQQ-like domain; Region: PQQ_2; pfam13360
1133852007652	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1133852007653	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1133852007654	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852007655	N-terminal plug; other site
1133852007656	ligand-binding site [chemical binding]; other site
1133852007657	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1133852007658	DNA-binding site [nucleotide binding]; DNA binding site
1133852007659	helix_turn_helix gluconate operon transcriptional repressor; Region: HTH_GNTR; smart00345
1133852007660	FCD domain; Region: FCD; pfam07729
1133852007661	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1133852007662	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1133852007663	NAD(P) binding site [chemical binding]; other site
1133852007664	substrate binding site [chemical binding]; other site
1133852007665	dimer interface [polypeptide binding]; other site
1133852007666	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1133852007667	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852007668	Coenzyme A binding pocket [chemical binding]; other site
1133852007669	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1133852007670	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1133852007671	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1133852007672	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1133852007673	trimer interface [polypeptide binding]; other site
1133852007674	active site
1133852007675	substrate binding site [chemical binding]; other site
1133852007676	CoA binding site [chemical binding]; other site
1133852007677	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1133852007678	tetrameric interface [polypeptide binding]; other site
1133852007679	NAD binding site [chemical binding]; other site
1133852007680	catalytic residues [active]
1133852007681	substrate binding site [chemical binding]; other site
1133852007682	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133852007683	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852007684	dimer interface [polypeptide binding]; other site
1133852007685	conserved gate region; other site
1133852007686	putative PBP binding loops; other site
1133852007687	ABC-ATPase subunit interface; other site
1133852007688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852007689	dimer interface [polypeptide binding]; other site
1133852007690	conserved gate region; other site
1133852007691	putative PBP binding loops; other site
1133852007692	ABC-ATPase subunit interface; other site
1133852007693	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1133852007694	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852007695	Walker A/P-loop; other site
1133852007696	ATP binding site [chemical binding]; other site
1133852007697	Q-loop/lid; other site
1133852007698	ABC transporter signature motif; other site
1133852007699	Walker B; other site
1133852007700	D-loop; other site
1133852007701	H-loop/switch region; other site
1133852007702	TOBE domain; Region: TOBE_2; pfam08402
1133852007703	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1133852007704	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1133852007705	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852007706	DNA-binding site [nucleotide binding]; DNA binding site
1133852007707	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852007708	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852007709	homodimer interface [polypeptide binding]; other site
1133852007710	catalytic residue [active]
1133852007711	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1133852007712	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852007713	sequence-specific DNA binding site [nucleotide binding]; other site
1133852007714	salt bridge; other site
1133852007715	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1133852007716	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1133852007717	Collagenase; Region: DUF3656; pfam12392
1133852007718	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133852007719	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852007720	non-specific DNA binding site [nucleotide binding]; other site
1133852007721	salt bridge; other site
1133852007722	sequence-specific DNA binding site [nucleotide binding]; other site
1133852007723	Cupin domain; Region: Cupin_2; pfam07883
1133852007724	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1133852007725	benzoate transporter; Region: benE; TIGR00843
1133852007726	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1133852007727	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1133852007728	Probable transposase; Region: OrfB_IS605; pfam01385
1133852007729	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1133852007730	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1133852007731	tellurite resistance protein TehB; Provisional; Region: PRK11207
1133852007732	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852007733	S-adenosylmethionine binding site [chemical binding]; other site
1133852007734	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1133852007735	gating phenylalanine in ion channel; other site
1133852007736	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1133852007737	putative trimer interface [polypeptide binding]; other site
1133852007738	putative CoA binding site [chemical binding]; other site
1133852007739	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1133852007740	putative trimer interface [polypeptide binding]; other site
1133852007741	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1133852007742	putative CoA binding site [chemical binding]; other site
1133852007743	putative trimer interface [polypeptide binding]; other site
1133852007744	putative CoA binding site [chemical binding]; other site
1133852007745	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1133852007746	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852007747	Coenzyme A binding pocket [chemical binding]; other site
1133852007748	hypothetical protein; Provisional; Region: PRK11415
1133852007749	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1133852007750	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1133852007751	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1133852007752	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852007753	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852007754	dimerization interface [polypeptide binding]; other site
1133852007755	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1133852007756	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133852007757	dimer interface [polypeptide binding]; other site
1133852007758	ligand binding site [chemical binding]; other site
1133852007759	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852007760	dimerization interface [polypeptide binding]; other site
1133852007761	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133852007762	dimer interface [polypeptide binding]; other site
1133852007763	putative CheW interface [polypeptide binding]; other site
1133852007764	small toxic polypeptide; Provisional; Region: PRK09738
1133852007765	hypothetical protein; Provisional; Region: PRK10040
1133852007766	cytochrome b561; Provisional; Region: PRK11513
1133852007767	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1133852007768	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1133852007769	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1133852007770	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1133852007771	NAD binding site [chemical binding]; other site
1133852007772	catalytic residues [active]
1133852007773	substrate binding site [chemical binding]; other site
1133852007774	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133852007775	putative active site [active]
1133852007776	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1133852007777	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852007778	ATP binding site [chemical binding]; other site
1133852007779	putative Mg++ binding site [ion binding]; other site
1133852007780	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852007781	nucleotide binding region [chemical binding]; other site
1133852007782	ATP-binding site [chemical binding]; other site
1133852007783	Helicase associated domain (HA2); Region: HA2; pfam04408
1133852007784	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1133852007785	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1133852007786	azoreductase; Reviewed; Region: PRK00170
1133852007787	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1133852007788	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133852007789	active site
1133852007790	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
1133852007791	Predicted protein-tyrosine phosphatase [Signal transduction mechanisms]; Region: CDC14; COG2453
1133852007792	active site
1133852007793	catalytic residues [active]
1133852007794	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1133852007795	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1133852007796	Putative methyltransferase; Region: Methyltransf_20; pfam12147
1133852007797	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852007798	S-adenosylmethionine binding site [chemical binding]; other site
1133852007799	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
1133852007800	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1133852007801	Protein of unknown function (DUF342); Region: DUF342; cl19219
1133852007802	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
1133852007803	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852007804	active site
1133852007805	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852007806	catalytic tetrad [active]
1133852007807	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
1133852007808	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1133852007809	putative trimer interface [polypeptide binding]; other site
1133852007810	putative metal binding site [ion binding]; other site
1133852007811	PaaX-like protein; Region: PaaX; pfam07848
1133852007812	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
1133852007813	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1133852007814	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
1133852007815	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1133852007816	active site
1133852007817	AMP binding site [chemical binding]; other site
1133852007818	homodimer interface [polypeptide binding]; other site
1133852007819	acyl-activating enzyme (AAE) consensus motif; other site
1133852007820	CoA binding site [chemical binding]; other site
1133852007821	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1133852007822	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133852007823	dimer interface [polypeptide binding]; other site
1133852007824	active site
1133852007825	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133852007826	CoenzymeA binding site [chemical binding]; other site
1133852007827	subunit interaction site [polypeptide binding]; other site
1133852007828	PHB binding site; other site
1133852007829	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
1133852007830	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1133852007831	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133852007832	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133852007833	enoyl-CoA hydratase; Provisional; Region: PRK08140
1133852007834	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852007835	substrate binding site [chemical binding]; other site
1133852007836	oxyanion hole (OAH) forming residues; other site
1133852007837	trimer interface [polypeptide binding]; other site
1133852007838	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1133852007839	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852007840	substrate binding site [chemical binding]; other site
1133852007841	oxyanion hole (OAH) forming residues; other site
1133852007842	trimer interface [polypeptide binding]; other site
1133852007843	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1133852007844	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1133852007845	FAD binding pocket [chemical binding]; other site
1133852007846	FAD binding motif [chemical binding]; other site
1133852007847	phosphate binding motif [ion binding]; other site
1133852007848	beta-alpha-beta structure motif; other site
1133852007849	NAD(p) ribose binding residues [chemical binding]; other site
1133852007850	NAD binding pocket [chemical binding]; other site
1133852007851	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1133852007852	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852007853	catalytic loop [active]
1133852007854	iron binding site [ion binding]; other site
1133852007855	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1133852007856	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1133852007857	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1133852007858	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
1133852007859	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1133852007860	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1133852007861	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1133852007862	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1133852007863	substrate binding site [chemical binding]; other site
1133852007864	dimer interface [polypeptide binding]; other site
1133852007865	NADP binding site [chemical binding]; other site
1133852007866	catalytic residues [active]
1133852007867	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
1133852007868	substrate binding site [chemical binding]; other site
1133852007869	tyramine oxidase; Provisional; Region: tynA; PRK14696
1133852007870	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1133852007871	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
1133852007872	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
1133852007873	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
1133852007874	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1133852007875	NAD(P) binding site [chemical binding]; other site
1133852007876	catalytic residues [active]
1133852007877	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
1133852007878	AraC-binding-like domain; Region: AraC_binding_2; pfam14525
1133852007879	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852007880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1133852007881	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1133852007882	hypothetical protein; Provisional; Region: PRK10695
1133852007883	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1133852007884	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1133852007885	putative ligand binding site [chemical binding]; other site
1133852007886	putative NAD binding site [chemical binding]; other site
1133852007887	catalytic site [active]
1133852007888	heat-inducible protein; Provisional; Region: PRK10449
1133852007889	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1133852007890	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1133852007891	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1133852007892	dimer interface [polypeptide binding]; other site
1133852007893	PYR/PP interface [polypeptide binding]; other site
1133852007894	TPP binding site [chemical binding]; other site
1133852007895	substrate binding site [chemical binding]; other site
1133852007896	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1133852007897	Domain of unknown function; Region: EKR; pfam10371
1133852007898	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1133852007899	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1133852007900	TPP-binding site [chemical binding]; other site
1133852007901	dimer interface [polypeptide binding]; other site
1133852007902	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133852007903	trimer interface [polypeptide binding]; other site
1133852007904	eyelet of channel; other site
1133852007905	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852007906	Ligand Binding Site [chemical binding]; other site
1133852007907	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1133852007908	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1133852007909	Ligand Binding Site [chemical binding]; other site
1133852007910	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1133852007911	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133852007912	ATP binding site [chemical binding]; other site
1133852007913	Mg++ binding site [ion binding]; other site
1133852007914	motif III; other site
1133852007915	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852007916	nucleotide binding region [chemical binding]; other site
1133852007917	ATP-binding site [chemical binding]; other site
1133852007918	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1133852007919	putative RNA binding site [nucleotide binding]; other site
1133852007920	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1133852007921	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1133852007922	Cl binding site [ion binding]; other site
1133852007923	oligomer interface [polypeptide binding]; other site
1133852007924	PAS domain S-box; Region: sensory_box; TIGR00229
1133852007925	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852007926	putative active site [active]
1133852007927	heme pocket [chemical binding]; other site
1133852007928	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852007929	metal binding site [ion binding]; metal-binding site
1133852007930	active site
1133852007931	I-site; other site
1133852007932	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1133852007933	Smr domain; Region: Smr; pfam01713
1133852007934	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1133852007935	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852007936	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1133852007937	putative substrate binding pocket [chemical binding]; other site
1133852007938	putative dimerization interface [polypeptide binding]; other site
1133852007939	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1133852007940	amidohydrolase; Region: amidohydrolases; TIGR01891
1133852007941	putative metal binding site [ion binding]; other site
1133852007942	dimer interface [polypeptide binding]; other site
1133852007943	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1133852007944	amidohydrolase; Region: amidohydrolases; TIGR01891
1133852007945	putative metal binding site [ion binding]; other site
1133852007946	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1133852007947	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1133852007948	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1133852007949	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1133852007950	DNA binding site [nucleotide binding]
1133852007951	active site
1133852007952	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1133852007953	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1133852007954	ligand binding site [chemical binding]; other site
1133852007955	flexible hinge region; other site
1133852007956	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1133852007957	putative switch regulator; other site
1133852007958	non-specific DNA interactions [nucleotide binding]; other site
1133852007959	DNA binding site [nucleotide binding]
1133852007960	sequence specific DNA binding site [nucleotide binding]; other site
1133852007961	putative cAMP binding site [chemical binding]; other site
1133852007962	universal stress protein UspE; Provisional; Region: PRK11175
1133852007963	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852007964	Ligand Binding Site [chemical binding]; other site
1133852007965	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852007966	Ligand Binding Site [chemical binding]; other site
1133852007967	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1133852007968	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1133852007969	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133852007970	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1133852007971	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1133852007972	peptide binding site [polypeptide binding]; other site
1133852007973	Uncharacterized BCR, COG1636; Region: DUF208; cl17782
1133852007974	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852007975	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852007976	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1133852007977	putative effector binding pocket; other site
1133852007978	putative dimerization interface [polypeptide binding]; other site
1133852007979	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1133852007980	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
1133852007981	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133852007982	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1133852007983	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1133852007984	putative active site [active]
1133852007985	Zn binding site [ion binding]; other site
1133852007986	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1133852007987	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1133852007988	active site
1133852007989	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1133852007990	dimer interface [polypeptide binding]; other site
1133852007991	catalytic triad [active]
1133852007992	peroxidatic and resolving cysteines [active]
1133852007993	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1133852007994	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1133852007995	putative aromatic amino acid binding site; other site
1133852007996	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852007997	putative active site [active]
1133852007998	heme pocket [chemical binding]; other site
1133852007999	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852008000	Walker A motif; other site
1133852008001	ATP binding site [chemical binding]; other site
1133852008002	Walker B motif; other site
1133852008003	arginine finger; other site
1133852008004	hypothetical protein; Provisional; Region: PRK05415
1133852008005	Predicted membrane protein [Function unknown]; Region: COG3768
1133852008006	Predicted ATPase [General function prediction only]; Region: COG3106
1133852008007	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133852008008	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852008009	DNA binding site [nucleotide binding]
1133852008010	domain linker motif; other site
1133852008011	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1133852008012	putative dimerization interface [polypeptide binding]; other site
1133852008013	putative ligand binding site [chemical binding]; other site
1133852008014	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
1133852008015	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1133852008016	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1133852008017	Walker A/P-loop; other site
1133852008018	ATP binding site [chemical binding]; other site
1133852008019	Q-loop/lid; other site
1133852008020	ABC transporter signature motif; other site
1133852008021	Walker B; other site
1133852008022	D-loop; other site
1133852008023	H-loop/switch region; other site
1133852008024	TOBE domain; Region: TOBE_2; pfam08402
1133852008025	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1133852008026	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852008027	motif II; other site
1133852008028	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1133852008029	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1133852008030	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1133852008031	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1133852008032	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1133852008033	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133852008034	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133852008035	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1133852008036	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1133852008037	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852008038	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1133852008039	putative NAD(P) binding site [chemical binding]; other site
1133852008040	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1133852008041	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008042	dimer interface [polypeptide binding]; other site
1133852008043	conserved gate region; other site
1133852008044	putative PBP binding loops; other site
1133852008045	ABC-ATPase subunit interface; other site
1133852008046	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1133852008047	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008048	dimer interface [polypeptide binding]; other site
1133852008049	conserved gate region; other site
1133852008050	putative PBP binding loops; other site
1133852008051	ABC-ATPase subunit interface; other site
1133852008052	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1133852008053	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1133852008054	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1133852008055	sucrose phosphorylase; Provisional; Region: PRK13840
1133852008056	active site
1133852008057	homodimer interface [polypeptide binding]; other site
1133852008058	catalytic site [active]
1133852008059	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1133852008060	active site residue [active]
1133852008061	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1133852008062	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1133852008063	phage shock protein C; Region: phageshock_pspC; TIGR02978
1133852008064	phage shock protein B; Provisional; Region: pspB; PRK09458
1133852008065	phage shock protein PspA; Provisional; Region: PRK10698
1133852008066	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1133852008067	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1133852008068	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852008069	Walker A motif; other site
1133852008070	ATP binding site [chemical binding]; other site
1133852008071	Walker B motif; other site
1133852008072	arginine finger; other site
1133852008073	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1133852008074	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852008075	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1133852008076	inhibitor-cofactor binding pocket; inhibition site
1133852008077	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852008078	catalytic residue [active]
1133852008079	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1133852008080	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1133852008081	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
1133852008082	NAD(P) binding site [chemical binding]; other site
1133852008083	catalytic residues [active]
1133852008084	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1133852008085	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852008086	non-specific DNA binding site [nucleotide binding]; other site
1133852008087	salt bridge; other site
1133852008088	sequence-specific DNA binding site [nucleotide binding]; other site
1133852008089	Cupin domain; Region: Cupin_2; pfam07883
1133852008090	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1133852008091	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1133852008092	catalytic triad [active]
1133852008093	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1133852008094	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1133852008095	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852008096	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1133852008097	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1133852008098	antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109
1133852008099	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1133852008100	peptide binding site [polypeptide binding]; other site
1133852008101	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SapB; COG4168
1133852008102	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008103	dimer interface [polypeptide binding]; other site
1133852008104	conserved gate region; other site
1133852008105	putative PBP binding loops; other site
1133852008106	ABC-ATPase subunit interface; other site
1133852008107	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1133852008108	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133852008109	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008110	dimer interface [polypeptide binding]; other site
1133852008111	conserved gate region; other site
1133852008112	putative PBP binding loops; other site
1133852008113	ABC-ATPase subunit interface; other site
1133852008114	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1133852008115	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852008116	Walker A/P-loop; other site
1133852008117	ATP binding site [chemical binding]; other site
1133852008118	Q-loop/lid; other site
1133852008119	ABC transporter signature motif; other site
1133852008120	Walker B; other site
1133852008121	D-loop; other site
1133852008122	H-loop/switch region; other site
1133852008123	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852008124	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1133852008125	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852008126	Walker A/P-loop; other site
1133852008127	ATP binding site [chemical binding]; other site
1133852008128	Q-loop/lid; other site
1133852008129	ABC transporter signature motif; other site
1133852008130	Walker B; other site
1133852008131	D-loop; other site
1133852008132	H-loop/switch region; other site
1133852008133	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1133852008134	putative active site [active]
1133852008135	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
1133852008136	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1133852008137	NAD binding site [chemical binding]; other site
1133852008138	homotetramer interface [polypeptide binding]; other site
1133852008139	homodimer interface [polypeptide binding]; other site
1133852008140	substrate binding site [chemical binding]; other site
1133852008141	active site
1133852008142	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1133852008143	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1133852008144	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1133852008145	exoribonuclease II; Provisional; Region: PRK05054
1133852008146	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1133852008147	RNB domain; Region: RNB; pfam00773
1133852008148	S1 RNA binding domain; Region: S1; pfam00575
1133852008149	RNase II stability modulator; Provisional; Region: PRK10060
1133852008150	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852008151	putative active site [active]
1133852008152	heme pocket [chemical binding]; other site
1133852008153	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852008154	metal binding site [ion binding]; metal-binding site
1133852008155	active site
1133852008156	I-site; other site
1133852008157	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852008158	hypothetical protein; Provisional; Region: PRK13658
1133852008159	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133852008160	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1133852008161	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852008162	lipoprotein; Provisional; Region: PRK10540
1133852008163	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1133852008164	putative rRNA binding site [nucleotide binding]; other site
1133852008165	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1133852008166	active site
1133852008167	dimer interface [polypeptide binding]; other site
1133852008168	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1133852008169	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852008170	TPR motif; other site
1133852008171	binding surface
1133852008172	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852008173	binding surface
1133852008174	TPR motif; other site
1133852008175	Predicted membrane protein [Function unknown]; Region: COG3771
1133852008176	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133852008177	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1133852008178	active site
1133852008179	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1133852008180	dimerization interface [polypeptide binding]; other site
1133852008181	active site
1133852008182	aconitate hydratase; Validated; Region: PRK09277
1133852008183	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1133852008184	substrate binding site [chemical binding]; other site
1133852008185	ligand binding site [chemical binding]; other site
1133852008186	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1133852008187	substrate binding site [chemical binding]; other site
1133852008188	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1133852008189	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852008190	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1133852008191	substrate binding site [chemical binding]; other site
1133852008192	putative dimerization interface [polypeptide binding]; other site
1133852008193	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1133852008194	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1133852008195	active site
1133852008196	interdomain interaction site; other site
1133852008197	putative metal-binding site [ion binding]; other site
1133852008198	nucleotide binding site [chemical binding]; other site
1133852008199	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1133852008200	domain I; other site
1133852008201	DNA binding groove [nucleotide binding]
1133852008202	phosphate binding site [ion binding]; other site
1133852008203	domain II; other site
1133852008204	domain III; other site
1133852008205	nucleotide binding site [chemical binding]; other site
1133852008206	catalytic site [active]
1133852008207	domain IV; other site
1133852008208	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133852008209	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1133852008210	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1133852008211	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1133852008212	hypothetical protein; Provisional; Region: PRK11037
1133852008213	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1133852008214	putative inner membrane peptidase; Provisional; Region: PRK11778
1133852008215	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1133852008216	tandem repeat interface [polypeptide binding]; other site
1133852008217	oligomer interface [polypeptide binding]; other site
1133852008218	active site residues [active]
1133852008219	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1133852008220	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1133852008221	NADP binding site [chemical binding]; other site
1133852008222	homodimer interface [polypeptide binding]; other site
1133852008223	active site
1133852008224	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1133852008225	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
1133852008226	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1133852008227	homodimer interface [polypeptide binding]; other site
1133852008228	Walker A motif; other site
1133852008229	ATP binding site [chemical binding]; other site
1133852008230	hydroxycobalamin binding site [chemical binding]; other site
1133852008231	Walker B motif; other site
1133852008232	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1133852008233	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852008234	RNA binding surface [nucleotide binding]; other site
1133852008235	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1133852008236	probable active site [active]
1133852008237	hypothetical protein; Provisional; Region: PRK11630
1133852008238	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1133852008239	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1133852008240	active site
1133852008241	anthranilate synthase component I; Provisional; Region: PRK13564
1133852008242	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1133852008243	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1133852008244	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1133852008245	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1133852008246	glutamine binding [chemical binding]; other site
1133852008247	catalytic triad [active]
1133852008248	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1133852008249	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1133852008250	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1133852008251	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1133852008252	active site
1133852008253	ribulose/triose binding site [chemical binding]; other site
1133852008254	phosphate binding site [ion binding]; other site
1133852008255	substrate (anthranilate) binding pocket [chemical binding]; other site
1133852008256	product (indole) binding pocket [chemical binding]; other site
1133852008257	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1133852008258	active site
1133852008259	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1133852008260	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852008261	catalytic residue [active]
1133852008262	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1133852008263	substrate binding site [chemical binding]; other site
1133852008264	active site
1133852008265	catalytic residues [active]
1133852008266	heterodimer interface [polypeptide binding]; other site
1133852008267	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1133852008268	dimerization interface [polypeptide binding]; other site
1133852008269	metal binding site [ion binding]; metal-binding site
1133852008270	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
1133852008271	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133852008272	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133852008273	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852008274	S-adenosylmethionine binding site [chemical binding]; other site
1133852008275	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133852008276	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133852008277	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852008278	Phage Tail Collar Domain; Region: Collar; pfam07484
1133852008279	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133852008280	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133852008281	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133852008282	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1133852008283	Interdomain contacts; other site
1133852008284	Cytokine receptor motif; other site
1133852008285	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133852008286	Fibronectin type III protein; Region: DUF3672; pfam12421
1133852008287	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133852008288	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133852008289	MPN+ (JAMM) motif; other site
1133852008290	Zinc-binding site [ion binding]; other site
1133852008291	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133852008292	NlpC/P60 family; Region: NLPC_P60; cl17555
1133852008293	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133852008294	Phage-related protein [Function unknown]; Region: COG4718
1133852008295	Phage-related minor tail protein [Function unknown]; Region: COG5281
1133852008296	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133852008297	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; cl19901
1133852008298	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
1133852008299	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1133852008300	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133852008301	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133852008302	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133852008303	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133852008304	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133852008305	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133852008306	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133852008307	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133852008308	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1133852008309	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133852008310	tandem repeat interface [polypeptide binding]; other site
1133852008311	oligomer interface [polypeptide binding]; other site
1133852008312	active site residues [active]
1133852008313	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1133852008314	gpW; Region: gpW; pfam02831
1133852008315	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133852008316	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1133852008317	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
1133852008318	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133852008319	catalytic residues [active]
1133852008320	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
1133852008321	Lysis protein S; Region: Lysis_S; pfam04971
1133852008322	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133852008323	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133852008324	anti-adapter protein IraM; Provisional; Region: PRK09919
1133852008325	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852008326	DNA methylase; Region: N6_N4_Mtase; pfam01555
1133852008327	MarR family; Region: MarR_2; cl17246
1133852008328	Antitermination protein; Region: Antiterm; pfam03589
1133852008329	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048
1133852008330	Antitermination protein; Region: Antiterm; pfam03589
1133852008331	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
1133852008332	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1133852008333	Hok/gef family; Region: HOK_GEF; pfam01848
1133852008334	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1133852008335	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1133852008336	Helix-turn-helix domain; Region: HTH_36; pfam13730
1133852008337	primosomal protein DnaI; Provisional; Region: PRK02854
1133852008338	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1133852008339	Helix-turn-helix domain; Region: HTH_17; pfam12728
1133852008340	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852008341	non-specific DNA binding site [nucleotide binding]; other site
1133852008342	salt bridge; other site
1133852008343	transcriptional repressor DicA; Reviewed; Region: PRK09706
1133852008344	sequence-specific DNA binding site [nucleotide binding]; other site
1133852008345	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
1133852008346	DicB protein; Region: DicB; pfam05358
1133852008347	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1133852008348	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1133852008349	active site
1133852008350	catalytic site [active]
1133852008351	substrate binding site [chemical binding]; other site
1133852008352	Excisionase-like protein; Region: Exc; pfam07825
1133852008353	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1133852008354	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133852008355	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1133852008356	dimer interface [polypeptide binding]; other site
1133852008357	active site
1133852008358	Int/Topo IB signature motif; other site
1133852008359	outer membrane protein W; Provisional; Region: PRK10959
1133852008360	hypothetical protein; Provisional; Region: PRK02868
1133852008361	intracellular septation protein A; Reviewed; Region: PRK00259
1133852008362	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1133852008363	transport protein TonB; Provisional; Region: PRK10819
1133852008364	Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; pfam03544
1133852008365	YciI-like protein; Reviewed; Region: PRK11370
1133852008366	voltage-gated potassium channel; Provisional; Region: PRK10537
1133852008367	Ion channel; Region: Ion_trans_2; pfam07885
1133852008368	TrkA-N domain; Region: TrkA_N; pfam02254
1133852008369	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1133852008370	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1133852008371	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1133852008372	putative active site [active]
1133852008373	catalytic site [active]
1133852008374	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1133852008375	putative active site [active]
1133852008376	catalytic site [active]
1133852008377	dsDNA-mimic protein; Reviewed; Region: PRK05094
1133852008378	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1133852008379	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852008380	Walker A/P-loop; other site
1133852008381	ATP binding site [chemical binding]; other site
1133852008382	Q-loop/lid; other site
1133852008383	ABC transporter signature motif; other site
1133852008384	Walker B; other site
1133852008385	D-loop; other site
1133852008386	H-loop/switch region; other site
1133852008387	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852008388	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1133852008389	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852008390	Walker A/P-loop; other site
1133852008391	ATP binding site [chemical binding]; other site
1133852008392	Q-loop/lid; other site
1133852008393	ABC transporter signature motif; other site
1133852008394	Walker B; other site
1133852008395	D-loop; other site
1133852008396	H-loop/switch region; other site
1133852008397	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852008398	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1133852008399	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133852008400	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008401	dimer interface [polypeptide binding]; other site
1133852008402	conserved gate region; other site
1133852008403	putative PBP binding loops; other site
1133852008404	ABC-ATPase subunit interface; other site
1133852008405	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1133852008406	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008407	dimer interface [polypeptide binding]; other site
1133852008408	conserved gate region; other site
1133852008409	putative PBP binding loops; other site
1133852008410	ABC-ATPase subunit interface; other site
1133852008411	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1133852008412	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1133852008413	peptide binding site [polypeptide binding]; other site
1133852008414	hypothetical protein; Provisional; Region: PRK11111
1133852008415	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1133852008416	Coenzyme A acylating aldehyde dehydrogenase (ACDH), Ethanolamine utilization protein EutE, and related proteins; Region: ALDH_F20_ACDH_EutE-like; cd07081
1133852008417	putative catalytic cysteine [active]
1133852008418	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1133852008419	putative active site [active]
1133852008420	metal binding site [ion binding]; metal-binding site
1133852008421	potential frameshift: common BLAST hit: gi|283787810|ref|YP_003367675.1| ISCro3 transposase
1133852008422	potential frameshift: common BLAST hit: gi|291285848|ref|YP_003502665.1| transposase, IS4 family protein
1133852008423	thymidine kinase; Provisional; Region: PRK04296
1133852008424	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1133852008425	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
1133852008426	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1133852008427	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1133852008428	active site
1133852008429	tetramer interface; other site
1133852008430	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852008431	active site
1133852008432	response regulator of RpoS; Provisional; Region: PRK10693
1133852008433	phosphorylation site [posttranslational modification]
1133852008434	intermolecular recognition site; other site
1133852008435	dimerization interface [polypeptide binding]; other site
1133852008436	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1133852008437	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1133852008438	active site
1133852008439	nucleophile elbow; other site
1133852008440	hypothetical protein; Provisional; Region: PRK01617
1133852008441	SEC-C motif; Region: SEC-C; cl19389
1133852008442	SEC-C motif; Region: SEC-C; cl19389
1133852008443	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1133852008444	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1133852008445	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1133852008446	putative active site [active]
1133852008447	putative substrate binding site [chemical binding]; other site
1133852008448	putative cosubstrate binding site; other site
1133852008449	catalytic site [active]
1133852008450	potential protein location (hypothetical protein O3K_14495 [Escherichia coli O104:H4 str. 2011C-3493]) that overlaps RNA (tRNA-Y)
1133852008451	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1133852008452	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1133852008453	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1133852008454	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852008455	Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711
1133852008456	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1133852008457	Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710
1133852008458	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1133852008459	[4Fe-4S] binding site [ion binding]; other site
1133852008460	molybdopterin cofactor binding site [chemical binding]; other site
1133852008461	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1133852008462	molybdopterin cofactor binding site; other site
1133852008463	lysophospholipid transporter LplT; Provisional; Region: PRK11195; cl19150
1133852008464	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1133852008465	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1133852008466	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1133852008467	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852008468	dimerization interface [polypeptide binding]; other site
1133852008469	Histidine kinase; Region: HisKA_3; pfam07730
1133852008470	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852008471	ATP binding site [chemical binding]; other site
1133852008472	Mg2+ binding site [ion binding]; other site
1133852008473	G-X-G motif; other site
1133852008474	transcriptional regulator NarL; Provisional; Region: PRK10651
1133852008475	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852008476	active site
1133852008477	phosphorylation site [posttranslational modification]
1133852008478	intermolecular recognition site; other site
1133852008479	dimerization interface [polypeptide binding]; other site
1133852008480	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852008481	DNA binding residues [nucleotide binding]
1133852008482	dimerization interface [polypeptide binding]; other site
1133852008483	putative invasin; Provisional; Region: PRK10177
1133852008484	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1133852008485	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1133852008486	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
1133852008487	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1133852008488	putative active site pocket [active]
1133852008489	dimerization interface [polypeptide binding]; other site
1133852008490	putative catalytic residue [active]
1133852008491	cation transport regulator; Reviewed; Region: chaB; PRK09582
1133852008492	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1133852008493	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1133852008494	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133852008495	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133852008496	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1133852008497	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1133852008498	hypothetical protein; Provisional; Region: PRK10941
1133852008499	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1133852008500	hypothetical protein; Provisional; Region: PRK10278
1133852008501	HemK family putative methylases; Region: hemK_fam; TIGR00536
1133852008502	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; cl17726
1133852008503	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852008504	S-adenosylmethionine binding site [chemical binding]; other site
1133852008505	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1133852008506	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1133852008507	RF-1 domain; Region: RF-1; pfam00472
1133852008508	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1133852008509	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1133852008510	tRNA; other site
1133852008511	putative tRNA binding site [nucleotide binding]; other site
1133852008512	putative NADP binding site [chemical binding]; other site
1133852008513	Glutamyl-tRNAGlu reductase, dimerization domain; Region: GlutR_dimer; pfam00745
1133852008514	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
1133852008515	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1133852008516	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1133852008517	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1133852008518	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1133852008519	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1133852008520	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852008521	active site
1133852008522	putative transporter; Provisional; Region: PRK11660
1133852008523	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1133852008524	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1133852008525	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1133852008526	hypothetical protein; Provisional; Region: PRK10692
1133852008527	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1133852008528	putative active site [active]
1133852008529	catalytic residue [active]
1133852008530	GTP-binding protein YchF; Reviewed; Region: PRK09601
1133852008531	YchF GTPase; Region: YchF; cd01900
1133852008532	G1 box; other site
1133852008533	GTP/Mg2+ binding site [chemical binding]; other site
1133852008534	Switch I region; other site
1133852008535	G2 box; other site
1133852008536	Switch II region; other site
1133852008537	G3 box; other site
1133852008538	G4 box; other site
1133852008539	G5 box; other site
1133852008540	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1133852008541	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133852008542	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852008543	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852008544	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
1133852008545	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852008546	putative active site [active]
1133852008547	heme pocket [chemical binding]; other site
1133852008548	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852008549	Walker A motif; other site
1133852008550	ATP binding site [chemical binding]; other site
1133852008551	Walker B motif; other site
1133852008552	arginine finger; other site
1133852008553	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133852008554	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1133852008555	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1133852008556	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1133852008557	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
1133852008558	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133852008559	dimerization domain swap beta strand [polypeptide binding]; other site
1133852008560	regulatory protein interface [polypeptide binding]; other site
1133852008561	active site
1133852008562	regulatory phosphorylation site [posttranslational modification]; other site
1133852008563	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
1133852008564	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133852008565	trehalase; Provisional; Region: treA; PRK13271
1133852008566	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1133852008567	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1133852008568	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1133852008569	Flagellar regulator YcgR; Region: YcgR; pfam07317
1133852008570	PilZ domain; Region: PilZ; pfam07238
1133852008571	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852008572	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852008573	catalytic residue [active]
1133852008574	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1133852008575	dimer interface [polypeptide binding]; other site
1133852008576	catalytic triad [active]
1133852008577	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1133852008578	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1133852008579	TrkA-C domain; Region: TrkA_C; pfam02080
1133852008580	Transporter associated domain; Region: CorC_HlyC; smart01091
1133852008581	alanine racemase; Reviewed; Region: dadX; PRK03646
1133852008582	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1133852008583	active site
1133852008584	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133852008585	substrate binding site [chemical binding]; other site
1133852008586	catalytic residues [active]
1133852008587	dimer interface [polypeptide binding]; other site
1133852008588	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1133852008589	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852008590	SpoVR family protein; Provisional; Region: PRK11767
1133852008591	fatty acid metabolism regulator; Provisional; Region: PRK04984
1133852008592	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852008593	DNA-binding site [nucleotide binding]; DNA binding site
1133852008594	FadR C-terminal domain; Region: FadR_C; pfam07840
1133852008595	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1133852008596	disulfide bond formation protein B; Provisional; Region: PRK01749
1133852008597	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1133852008598	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1133852008599	active site
1133852008600	DNA binding site [nucleotide binding]
1133852008601	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1133852008602	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1133852008603	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852008604	Catalytic site [active]
1133852008605	potential frameshift: common BLAST hit: gi|15830931|ref|NP_309704.1| hemolysin E
1133852008606	Haemolysin E (HlyE); Region: HlyE; cl11627
1133852008607	hypothetical protein; Provisional; Region: PRK05170
1133852008608	hypothetical protein; Provisional; Region: PRK10691
1133852008609	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1133852008610	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1133852008611	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
1133852008612	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
1133852008613	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
1133852008614	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1133852008615	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1133852008616	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1133852008617	cell division inhibitor MinD; Provisional; Region: PRK10818
1133852008618	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1133852008619	P-loop; other site
1133852008620	ADP binding residues [chemical binding]; other site
1133852008621	Switch I; other site
1133852008622	Switch II; other site
1133852008623	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1133852008624	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852008625	Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436
1133852008626	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133852008627	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852008628	Autotransporter beta-domain; Region: Autotransporter; smart00869
1133852008629	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1133852008630	phage resistance protein; Provisional; Region: PRK10551
1133852008631	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133852008632	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852008633	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1133852008634	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1133852008635	Sensors of blue-light using FAD; Region: BLUF; smart01034
1133852008636	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852008637	transcriptional regulator MirA; Provisional; Region: PRK15043
1133852008638	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1133852008639	DNA binding residues [nucleotide binding]
1133852008640	Phage envelope protein [General function prediction only]; Region: COG5562
1133852008641	anti-adapter protein IraM; Provisional; Region: PRK09919
1133852008642	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1133852008643	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1133852008644	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1133852008645	probable active site [active]
1133852008646	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1133852008647	nudix motif; other site
1133852008648	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1133852008649	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1133852008650	Ligand Binding Site [chemical binding]; other site
1133852008651	putative lysogenization regulator; Reviewed; Region: PRK00218
1133852008652	adenylosuccinate lyase; Provisional; Region: PRK09285
1133852008653	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1133852008654	tetramer interface [polypeptide binding]; other site
1133852008655	active site
1133852008656	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1133852008657	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852008658	active site
1133852008659	phosphorylation site [posttranslational modification]
1133852008660	intermolecular recognition site; other site
1133852008661	dimerization interface [polypeptide binding]; other site
1133852008662	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852008663	DNA binding site [nucleotide binding]
1133852008664	sensor protein PhoQ; Provisional; Region: PRK10815
1133852008665	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1133852008666	HAMP domain; Region: HAMP; pfam00672
1133852008667	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1133852008668	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852008669	ATP binding site [chemical binding]; other site
1133852008670	Mg2+ binding site [ion binding]; other site
1133852008671	G-X-G motif; other site
1133852008672	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1133852008673	peptidase T-like protein; Region: PepT-like; TIGR01883
1133852008674	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1133852008675	metal binding site [ion binding]; metal-binding site
1133852008676	dimer interface [polypeptide binding]; other site
1133852008677	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1133852008678	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1133852008679	Walker A/P-loop; other site
1133852008680	ATP binding site [chemical binding]; other site
1133852008681	Q-loop/lid; other site
1133852008682	ABC transporter signature motif; other site
1133852008683	Walker B; other site
1133852008684	D-loop; other site
1133852008685	H-loop/switch region; other site
1133852008686	TOBE domain; Region: TOBE_2; pfam08402
1133852008687	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133852008688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008689	dimer interface [polypeptide binding]; other site
1133852008690	conserved gate region; other site
1133852008691	putative PBP binding loops; other site
1133852008692	ABC-ATPase subunit interface; other site
1133852008693	spermidine/putrescine ABC transporter membrane protein; Reviewed; Region: potC; PRK09500
1133852008694	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852008695	dimer interface [polypeptide binding]; other site
1133852008696	conserved gate region; other site
1133852008697	putative PBP binding loops; other site
1133852008698	ABC-ATPase subunit interface; other site
1133852008699	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1133852008700	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1133852008701	TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase; Region: TPM; cl01535
1133852008702	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1133852008703	NAD+ binding site [chemical binding]; other site
1133852008704	substrate binding site [chemical binding]; other site
1133852008705	Zn binding site [ion binding]; other site
1133852008706	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133852008707	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852008708	nucleotide binding site [chemical binding]; other site
1133852008709	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1133852008710	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133852008711	FtsX-like permease family; Region: FtsX; pfam02687
1133852008712	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1133852008713	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133852008714	Walker A/P-loop; other site
1133852008715	ATP binding site [chemical binding]; other site
1133852008716	Q-loop/lid; other site
1133852008717	ABC transporter signature motif; other site
1133852008718	Walker B; other site
1133852008719	D-loop; other site
1133852008720	H-loop/switch region; other site
1133852008721	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1133852008722	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133852008723	FtsX-like permease family; Region: FtsX; pfam02687
1133852008724	Predicted membrane protein [Function unknown]; Region: COG4763
1133852008725	transcription-repair coupling factor; Provisional; Region: PRK10689
1133852008726	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
1133852008727	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1133852008728	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852008729	ATP binding site [chemical binding]; other site
1133852008730	putative Mg++ binding site [ion binding]; other site
1133852008731	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852008732	nucleotide binding region [chemical binding]; other site
1133852008733	ATP-binding site [chemical binding]; other site
1133852008734	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1133852008735	L,D-transpeptidase; Provisional; Region: PRK10260
1133852008736	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852008737	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133852008738	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852008739	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133852008740	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852008741	hypothetical protein; Provisional; Region: PRK11280
1133852008742	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1133852008743	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852008744	hypothetical protein; Provisional; Region: PRK04940
1133852008745	beta-hexosaminidase; Provisional; Region: PRK05337
1133852008746	Phosphotransferase enzyme family; Region: APH; pfam01636
1133852008747	active site
1133852008748	substrate binding site [chemical binding]; other site
1133852008749	ATP binding site [chemical binding]; other site
1133852008750	thiamine kinase; Provisional; Region: thiK; PRK10271
1133852008751	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1133852008752	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1133852008753	putative dimer interface [polypeptide binding]; other site
1133852008754	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1133852008755	nucleotide binding site/active site [active]
1133852008756	HIT family signature motif; other site
1133852008757	catalytic residue [active]
1133852008758	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1133852008759	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852008760	N-terminal plug; other site
1133852008761	ligand-binding site [chemical binding]; other site
1133852008762	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1133852008763	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133852008764	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852008765	active site turn [active]
1133852008766	phosphorylation site [posttranslational modification]
1133852008767	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1133852008768	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1133852008769	active site
1133852008770	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1133852008771	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1133852008772	thymidylate kinase; Validated; Region: tmk; PRK00698
1133852008773	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1133852008774	TMP-binding site; other site
1133852008775	ATP-binding site [chemical binding]; other site
1133852008776	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1133852008777	dimerization interface [polypeptide binding]; other site
1133852008778	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1133852008779	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852008780	catalytic residue [active]
1133852008781	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1133852008782	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1133852008783	dimer interface [polypeptide binding]; other site
1133852008784	active site
1133852008785	acyl carrier protein; Provisional; Region: acpP; PRK00982
1133852008786	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1133852008787	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1133852008788	NAD(P) binding site [chemical binding]; other site
1133852008789	homotetramer interface [polypeptide binding]; other site
1133852008790	homodimer interface [polypeptide binding]; other site
1133852008791	active site
1133852008792	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1133852008793	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1133852008794	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1133852008795	dimer interface [polypeptide binding]; other site
1133852008796	active site
1133852008797	CoA binding pocket [chemical binding]; other site
1133852008798	putative phosphate acyltransferase; Provisional; Region: PRK05331
1133852008799	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1133852008800	hypothetical protein; Provisional; Region: PRK11193
1133852008801	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1133852008802	active site
1133852008803	dimer interface [polypeptide binding]; other site
1133852008804	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1133852008805	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852008806	RNA binding surface [nucleotide binding]; other site
1133852008807	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1133852008808	active site
1133852008809	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
1133852008810	ribonuclease E; Reviewed; Region: rne; PRK10811
1133852008811	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1133852008812	homodimer interface [polypeptide binding]; other site
1133852008813	oligonucleotide binding site [chemical binding]; other site
1133852008814	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1133852008815	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1133852008816	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1133852008817	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1133852008818	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1133852008819	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133852008820	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133852008821	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1133852008822	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1133852008823	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1133852008824	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1133852008825	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1133852008826	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1133852008827	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133852008828	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133852008829	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1133852008830	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133852008831	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1133852008832	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1133852008833	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133852008834	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1133852008835	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133852008836	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1133852008837	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1133852008838	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1133852008839	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1133852008840	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1133852008841	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1133852008842	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1133852008843	flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173
1133852008844	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1133852008845	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1133852008846	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1133852008847	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1133852008848	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1133852008849	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1133852008850	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1133852008851	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1133852008852	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1133852008853	hypothetical protein; Provisional; Region: PRK11239
1133852008854	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1133852008855	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1133852008856	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1133852008857	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852008858	putative substrate translocation pore; other site
1133852008859	glutaredoxin 2; Provisional; Region: PRK10387
1133852008860	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1133852008861	C-terminal domain interface [polypeptide binding]; other site
1133852008862	GSH binding site (G-site) [chemical binding]; other site
1133852008863	catalytic residues [active]
1133852008864	putative dimer interface [polypeptide binding]; other site
1133852008865	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1133852008866	N-terminal domain interface [polypeptide binding]; other site
1133852008867	lipoprotein; Provisional; Region: PRK10598
1133852008868	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1133852008869	active site
1133852008870	substrate binding pocket [chemical binding]; other site
1133852008871	dimer interface [polypeptide binding]; other site
1133852008872	DNA damage-inducible protein I; Provisional; Region: PRK10597
1133852008873	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1133852008874	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1133852008875	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1133852008876	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1133852008877	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1133852008878	hypothetical protein; Provisional; Region: PRK03757
1133852008879	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1133852008880	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1133852008881	active site residue [active]
1133852008882	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133852008883	putative acyl-acceptor binding pocket; other site
1133852008884	drug efflux system protein MdtG; Provisional; Region: PRK09874
1133852008885	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852008886	putative substrate translocation pore; other site
1133852008887	secY/secA suppressor protein; Provisional; Region: PRK11467
1133852008888	lipoprotein; Provisional; Region: PRK10175
1133852008889	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1133852008890	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1133852008891	Ligand binding site; other site
1133852008892	DXD motif; other site
1133852008893	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1133852008894	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1133852008895	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1133852008896	PLD-like domain; Region: PLDc_2; pfam13091
1133852008897	putative active site [active]
1133852008898	catalytic site [active]
1133852008899	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1133852008900	PLD-like domain; Region: PLDc_2; pfam13091
1133852008901	putative active site [active]
1133852008902	catalytic site [active]
1133852008903	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1133852008904	putative ADP-ribose binding site [chemical binding]; other site
1133852008905	putative active site [active]
1133852008906	Thin aggregative fimbriae synthesis protein; Region: Tafi-CsgC; cl11667
1133852008907	major curlin subunit; Provisional; Region: csgA; PRK10051
1133852008908	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1133852008909	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1133852008910	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1133852008911	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1133852008912	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852008913	DNA binding residues [nucleotide binding]
1133852008914	dimerization interface [polypeptide binding]; other site
1133852008915	curli assembly protein CsgE; Provisional; Region: PRK10386
1133852008916	curli assembly protein CsgF; Provisional; Region: PRK10050
1133852008917	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1133852008918	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1133852008919	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1133852008920	putative hydrolase; Validated; Region: PRK09248
1133852008921	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1133852008922	active site
1133852008923	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1133852008924	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1133852008925	putative ligand binding site [chemical binding]; other site
1133852008926	NAD binding site [chemical binding]; other site
1133852008927	dimerization interface [polypeptide binding]; other site
1133852008928	catalytic site [active]
1133852008929	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133852008930	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133852008931	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133852008932	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133852008933	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133852008934	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133852008935	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133852008936	MPN+ (JAMM) motif; other site
1133852008937	Zinc-binding site [ion binding]; other site
1133852008938	Antirestriction protein; Region: Antirestrict; pfam03230
1133852008939	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133852008940	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1133852008941	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
1133852008942	active site
1133852008943	nucleophile elbow; other site
1133852008944	YjcZ-like protein; Region: YjcZ; pfam13990
1133852008945	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133852008946	G1 box; other site
1133852008947	GTP/Mg2+ binding site [chemical binding]; other site
1133852008948	G2 box; other site
1133852008949	Switch I region; other site
1133852008950	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1133852008951	G3 box; other site
1133852008952	Switch II region; other site
1133852008953	G4 box; other site
1133852008954	potential frameshift: common BLAST hit: gi|260858461|ref|YP_003232352.1| adhesin
1133852008955	potential frameshift: common BLAST hit: gi|260858461|ref|YP_003232352.1| adhesin
1133852008956	Predicted GTPase [General function prediction only]; Region: COG3596
1133852008957	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852008958	YfjP GTPase; Region: YfjP; cd11383
1133852008959	G1 box; other site
1133852008960	GTP/Mg2+ binding site [chemical binding]; other site
1133852008961	Switch I region; other site
1133852008962	G2 box; other site
1133852008963	Switch II region; other site
1133852008964	G3 box; other site
1133852008965	G4 box; other site
1133852008966	G5 box; other site
1133852008967	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852008968	Transposase; Region: HTH_Tnp_1; pfam01527
1133852008969	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008970	putative metal binding site [ion binding]; other site
1133852008971	vWA found in TerF C terminus; Region: vWA-TerF-like; pfam10138
1133852008972	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008973	putative metal binding site [ion binding]; other site
1133852008974	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008975	putative metal binding site [ion binding]; other site
1133852008976	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1133852008977	tellurite resistance protein terB; Region: terB; cd07176
1133852008978	putative metal binding site [ion binding]; other site
1133852008979	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008980	putative metal binding site [ion binding]; other site
1133852008981	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008982	putative metal binding site [ion binding]; other site
1133852008983	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008984	putative metal binding site [ion binding]; other site
1133852008985	ATP-grasp in the biosynthetic pathway with Ter operon; Region: ATPgrasp_Ter; pfam15632
1133852008986	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1133852008987	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852008988	active site
1133852008989	TRSP domain C terminus to PRTase_2; Region: TRSP; pfam12500
1133852008990	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
1133852008991	Phosphoribosyl transferase (PRTase); Region: PRTase_1; pfam11202
1133852008992	PELOTA RNA binding domain; Region: PELOTA_1; pfam15608
1133852008993	C-C_Bond_Lyase of the TIM-Barrel fold; Region: C-C_Bond_Lyase; pfam15617
1133852008994	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
1133852008995	Predicted transcriptional regulator [Transcription]; Region: COG2378
1133852008996	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133852008997	metal ion-dependent adhesion site (MIDAS); other site
1133852008998	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1133852008999	putative metal binding site [ion binding]; other site
1133852009000	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133852009001	metal ion-dependent adhesion site (MIDAS); other site
1133852009002	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1133852009003	metal ion-dependent adhesion site (MIDAS); other site
1133852009004	TerY-C metal binding domain; Region: TerY-C; pfam15616
1133852009005	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1133852009006	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1133852009007	substrate binding site [chemical binding]; other site
1133852009008	activation loop (A-loop); other site
1133852009009	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133852009010	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1133852009011	DNA-binding interface [nucleotide binding]; DNA binding site
1133852009012	Integrase core domain; Region: rve; pfam00665
1133852009013	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
1133852009014	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
1133852009015	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1133852009016	cell density-dependent motility repressor; Provisional; Region: PRK10082
1133852009017	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852009018	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133852009019	dimerization interface [polypeptide binding]; other site
1133852009020	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1133852009021	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1133852009022	HTH-like domain; Region: HTH_21; pfam13276
1133852009023	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133852009024	Integrase core domain; Region: rve; pfam00665
1133852009025	Integrase core domain; Region: rve_3; pfam13683
1133852009026	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133852009027	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133852009028	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852009029	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852009030	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852009031	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133852009032	Active Sites [active]
1133852009033	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1133852009034	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1133852009035	Part of AAA domain; Region: AAA_19; pfam13245
1133852009036	AAA domain; Region: AAA_12; pfam13087
1133852009037	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
1133852009038	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1133852009039	CAAX protease self-immunity; Region: Abi; pfam02517
1133852009040	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1133852009041	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
1133852009042	putative active site [active]
1133852009043	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852009044	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852009045	Walker A/P-loop; other site
1133852009046	ATP binding site [chemical binding]; other site
1133852009047	Q-loop/lid; other site
1133852009048	ABC transporter signature motif; other site
1133852009049	Walker B; other site
1133852009050	D-loop; other site
1133852009051	H-loop/switch region; other site
1133852009052	HlyD family secretion protein; Region: HlyD; pfam00529
1133852009053	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1133852009054	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852009055	RTX toxin acyltransferase family; Region: HlyC; pfam02794
1133852009056	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852009057	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852009058	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852009059	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133852009060	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1133852009061	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
1133852009062	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1133852009063	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1133852009064	active site
1133852009065	TDP-binding site; other site
1133852009066	acceptor substrate-binding pocket; other site
1133852009067	homodimer interface [polypeptide binding]; other site
1133852009068	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1133852009069	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
1133852009070	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
1133852009071	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852009072	N-terminal plug; other site
1133852009073	ligand-binding site [chemical binding]; other site
1133852009074	DEXH box helicase, DNA ligase-associated; Region: DEXH_lig_assoc; TIGR04121
1133852009075	Transposase; Region: HTH_Tnp_1; pfam01527
1133852009076	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852009077	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852009078	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852009079	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4951
1133852009080	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133852009081	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852009082	ATP binding site [chemical binding]; other site
1133852009083	putative Mg++ binding site [ion binding]; other site
1133852009084	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852009085	nucleotide binding region [chemical binding]; other site
1133852009086	ATP-binding site [chemical binding]; other site
1133852009087	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133852009088	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1133852009089	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
1133852009090	integrase; Provisional; Region: PRK09692
1133852009091	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852009092	active site
1133852009093	Int/Topo IB signature motif; other site
1133852009094	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1133852009095	Transposase; Region: HTH_Tnp_1; cl17663
1133852009096	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852009097	putative transposase OrfB; Reviewed; Region: PHA02517
1133852009098	HTH-like domain; Region: HTH_21; pfam13276
1133852009099	Integrase core domain; Region: rve; pfam00665
1133852009100	Integrase core domain; Region: rve_2; pfam13333
1133852009101	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852009102	metal binding site [ion binding]; metal-binding site
1133852009103	active site
1133852009104	I-site; other site
1133852009105	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
1133852009106	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
1133852009107	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
1133852009108	putative active site [active]
1133852009109	putative metal binding site [ion binding]; other site
1133852009110	Hypothetical glycosyl hydrolase family 13; Region: GHL13; pfam14883
1133852009111	N-glycosyltransferase; Provisional; Region: PRK11204
1133852009112	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1133852009113	DXD motif; other site
1133852009114	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
1133852009115	hypothetical protein; Provisional; Region: PRK10536
1133852009116	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1133852009117	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1133852009118	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1133852009119	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1133852009120	Imelysin; Region: Peptidase_M75; pfam09375
1133852009121	FTR1 family protein; Region: TIGR00145
1133852009122	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1133852009123	Na binding site [ion binding]; other site
1133852009124	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1133852009125	Predicted transcriptional regulator [Transcription]; Region: COG3905
1133852009126	DNA-binding domain of Proline dehydrogenase; Region: Pro_dh-DNA_bdg; pfam14850
1133852009127	Proline dehydrogenase; Region: Pro_dh; pfam01619
1133852009128	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1133852009129	Glutamate binding site [chemical binding]; other site
1133852009130	NAD binding site [chemical binding]; other site
1133852009131	catalytic residues [active]
1133852009132	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1133852009133	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1133852009134	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852009135	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1133852009136	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1133852009137	active site
1133852009138	dimer interface [polypeptide binding]; other site
1133852009139	non-prolyl cis peptide bond; other site
1133852009140	insertion regions; other site
1133852009141	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133852009142	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1133852009143	catalytic triad [active]
1133852009144	conserved cis-peptide bond; other site
1133852009145	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1133852009146	homotrimer interaction site [polypeptide binding]; other site
1133852009147	putative active site [active]
1133852009148	pyrimidine utilization protein D; Region: RutD; TIGR03611
1133852009149	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1133852009150	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1133852009151	putative FMN binding site [chemical binding]; other site
1133852009152	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1133852009153	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1133852009154	uracil-xanthine permease; Region: ncs2; TIGR00801
1133852009155	General stress protein [General function prediction only]; Region: GsiB; COG3729
1133852009156	Protein of unknown function (DUF499); Region: DUF499; cl19819
1133852009157	Borrelia burgdorferi protein of unknown function (DUF759); Region: DUF759; pfam05537
1133852009158	Hok/gef family; Region: HOK_GEF; pfam01848
1133852009159	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133852009160	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133852009161	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133852009162	Phage tail fibre adhesin Gp38; Region: GP38; pfam05268
1133852009163	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1133852009164	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852009165	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852009166	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852009167	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852009168	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1133852009169	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1133852009170	adaptive-response sensory kinase; Validated; Region: PRK09303
1133852009171	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
1133852009172	large terminase protein; Provisional; Region: 17; PHA02533
1133852009173	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
1133852009174	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1133852009175	ORF11CD3 domain; Region: ORF11CD3; pfam10549
1133852009176	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
1133852009177	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
1133852009178	ORF11CD3 domain; Region: ORF11CD3; pfam10549
1133852009179	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133852009180	catalytic residues [active]
1133852009181	Lysis protein S; Region: Lysis_S; pfam04971
1133852009182	Protein of unknown function (DUF826); Region: DUF826; pfam05696
1133852009183	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
1133852009184	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
1133852009185	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1133852009186	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133852009187	Shiga-like toxin beta subunit; Region: SLT_beta; pfam02258
1133852009188	Ribosome inactivating protein; Region: RIP; pfam00161
1133852009189	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133852009190	Phage NinH protein; Region: Phage_NinH; pfam06322
1133852009191	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1133852009192	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1133852009193	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1133852009194	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
1133852009195	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1133852009196	active site
1133852009197	metal binding site [ion binding]; metal-binding site
1133852009198	interdomain interaction site; other site
1133852009199	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1133852009200	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852009201	ATP binding site [chemical binding]; other site
1133852009202	putative Mg++ binding site [ion binding]; other site
1133852009203	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852009204	nucleotide binding region [chemical binding]; other site
1133852009205	ATP-binding site [chemical binding]; other site
1133852009206	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1133852009207	Cro; Region: Cro; pfam09048
1133852009208	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852009209	non-specific DNA binding site [nucleotide binding]; other site
1133852009210	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1133852009211	salt bridge; other site
1133852009212	sequence-specific DNA binding site [nucleotide binding]; other site
1133852009213	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852009214	Catalytic site [active]
1133852009215	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852009216	S-adenosylmethionine binding site [chemical binding]; other site
1133852009217	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1133852009218	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
1133852009219	Ash protein family; Region: Phage_ASH; pfam10554
1133852009220	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1133852009221	ORF6N domain; Region: ORF6N; pfam10543
1133852009222	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1133852009223	RecT family; Region: RecT; pfam03837
1133852009224	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1133852009225	Uncharacterized conserved protein (DUF2303); Region: DUF2303; cl02338
1133852009226	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133852009227	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1133852009228	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1133852009229	Phage anti-repressor protein [Transcription]; Region: COG3561
1133852009230	MT-A70; Region: MT-A70; cl01947
1133852009231	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
1133852009232	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
1133852009233	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133852009234	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1133852009235	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1133852009236	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133852009237	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1133852009238	Int/Topo IB signature motif; other site
1133852009239	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1133852009240	hypothetical protein; Provisional; Region: PRK10174
1133852009241	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1133852009242	catalytic core [active]
1133852009243	hypothetical protein; Provisional; Region: PRK09784
1133852009244	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1133852009245	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133852009246	HSP70 interaction site [polypeptide binding]; other site
1133852009247	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1133852009248	substrate binding site [polypeptide binding]; other site
1133852009249	dimer interface [polypeptide binding]; other site
1133852009250	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1133852009251	chaperone protein TorD; Validated; Region: torD; PRK04976
1133852009252	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1133852009253	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1133852009254	molybdopterin cofactor binding site [chemical binding]; other site
1133852009255	substrate binding site [chemical binding]; other site
1133852009256	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1133852009257	molybdopterin cofactor binding site; other site
1133852009258	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1133852009259	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1133852009260	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
1133852009261	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852009262	active site
1133852009263	phosphorylation site [posttranslational modification]
1133852009264	intermolecular recognition site; other site
1133852009265	dimerization interface [polypeptide binding]; other site
1133852009266	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852009267	DNA binding site [nucleotide binding]
1133852009268	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
1133852009269	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
1133852009270	putative ligand binding site [chemical binding]; other site
1133852009271	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1133852009272	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852009273	dimerization interface [polypeptide binding]; other site
1133852009274	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852009275	dimer interface [polypeptide binding]; other site
1133852009276	phosphorylation site [posttranslational modification]
1133852009277	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852009278	ATP binding site [chemical binding]; other site
1133852009279	Mg2+ binding site [ion binding]; other site
1133852009280	G-X-G motif; other site
1133852009281	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852009282	active site
1133852009283	phosphorylation site [posttranslational modification]
1133852009284	intermolecular recognition site; other site
1133852009285	dimerization interface [polypeptide binding]; other site
1133852009286	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1133852009287	putative binding surface; other site
1133852009288	active site
1133852009289	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1133852009290	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1133852009291	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1133852009292	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852009293	GnsA/GnsB family; Region: GnsAB; pfam08178
1133852009294	cold shock gene; Provisional; Region: PRK09891
1133852009295	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133852009296	DNA-binding site [nucleotide binding]; DNA binding site
1133852009297	RNA-binding motif; other site
1133852009298	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133852009299	DNA-binding site [nucleotide binding]; DNA binding site
1133852009300	RNA-binding motif; other site
1133852009301	Group 4 capsule polysaccharide formation lipoprotein gfcB; Region: Cap_synth_GfcB; pfam11102
1133852009302	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1133852009303	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1133852009304	polysaccharide export protein Wza; Provisional; Region: PRK15078
1133852009305	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1133852009306	SLBB domain; Region: SLBB; pfam10531
1133852009307	SLBB domain; Region: SLBB; pfam10531
1133852009308	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1133852009309	active site
1133852009310	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
1133852009311	Chain length determinant protein; Region: Wzz; pfam02706
1133852009312	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133852009313	AAA domain; Region: AAA_31; pfam13614
1133852009314	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1133852009315	catalytic core [active]
1133852009316	hypothetical protein; Provisional; Region: PRK14749
1133852009317	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1133852009318	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1133852009319	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1133852009320	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1133852009321	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1133852009322	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1133852009323	putative substrate-binding site; other site
1133852009324	nickel binding site [ion binding]; other site
1133852009325	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1133852009326	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1133852009327	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1133852009328	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1133852009329	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1133852009330	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
1133852009331	YccA-like proteins; Region: YccA_like; cd10433
1133852009332	sulfur transfer protein TusE; Provisional; Region: PRK11508
1133852009333	acylphosphatase; Provisional; Region: PRK14426
1133852009334	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1133852009335	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1133852009336	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1133852009337	putative RNA binding site [nucleotide binding]; other site
1133852009338	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852009339	S-adenosylmethionine binding site [chemical binding]; other site
1133852009340	heat shock protein HspQ; Provisional; Region: PRK14129
1133852009341	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1133852009342	hypothetical protein; Provisional; Region: PRK03641
1133852009343	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1133852009344	active site
1133852009345	dimer interfaces [polypeptide binding]; other site
1133852009346	catalytic residues [active]
1133852009347	DNA helicase IV; Provisional; Region: helD; PRK11054
1133852009348	DNA helicase IV / RNA helicase N terminal; Region: Helicase_IV_N; pfam12462
1133852009349	Part of AAA domain; Region: AAA_19; pfam13245
1133852009350	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1133852009351	Predicted membrane protein [Function unknown]; Region: COG3304
1133852009352	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1133852009353	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1133852009354	TIGR01666 family membrane protein; Region: YCCS
1133852009355	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1133852009356	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133852009357	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1133852009358	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1133852009359	cell division inhibitor SulA; Region: sula; TIGR00623
1133852009360	outer membrane protein A; Reviewed; Region: PRK10808
1133852009361	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1133852009362	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133852009363	ligand binding site [chemical binding]; other site
1133852009364	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1133852009365	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1133852009366	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1133852009367	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1133852009368	active site 1 [active]
1133852009369	dimer interface [polypeptide binding]; other site
1133852009370	active site 2 [active]
1133852009371	ribosome modulation factor; Provisional; Region: PRK14563
1133852009372	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1133852009373	paraquat-inducible protein B; Provisional; Region: PRK10807
1133852009374	mce related protein; Region: MCE; pfam02470
1133852009375	mce related protein; Region: MCE; pfam02470
1133852009376	mce related protein; Region: MCE; pfam02470
1133852009377	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
1133852009378	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1133852009379	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133852009380	Paraquat-inducible protein A; Region: PqiA; pfam04403
1133852009381	ABC transporter ATPase component; Reviewed; Region: PRK11147
1133852009382	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852009383	ABC transporter; Region: ABC_tran_2; pfam12848
1133852009384	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852009385	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1133852009386	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1133852009387	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1133852009388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852009389	S-adenosylmethionine binding site [chemical binding]; other site
1133852009390	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1133852009391	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1133852009392	MOSC domain; Region: MOSC; pfam03473
1133852009393	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852009394	catalytic loop [active]
1133852009395	iron binding site [ion binding]; other site
1133852009396	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1133852009397	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1133852009398	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1133852009399	quinone interaction residues [chemical binding]; other site
1133852009400	active site
1133852009401	catalytic residues [active]
1133852009402	FMN binding site [chemical binding]; other site
1133852009403	substrate binding site [chemical binding]; other site
1133852009404	putativi pili assembly chaperone; Provisional; Region: PRK11385
1133852009405	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852009406	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852009407	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133852009408	Fimbrial protein; Region: Fimbrial; cl01416
1133852009409	Fimbrial protein; Region: Fimbrial; cl01416
1133852009410	outer membrane usher protein; Provisional; Region: PRK15193
1133852009411	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852009412	Outer membrane usher protein; Region: Usher; pfam00577
1133852009413	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852009414	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1133852009415	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852009416	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852009417	Fimbrial protein; Region: Fimbrial; cl01416
1133852009418	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1133852009419	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852009420	substrate binding pocket [chemical binding]; other site
1133852009421	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1133852009422	membrane-bound complex binding site; other site
1133852009423	hinge residues; other site
1133852009424	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1133852009425	active site
1133852009426	dimer interface [polypeptide binding]; other site
1133852009427	non-prolyl cis peptide bond; other site
1133852009428	insertion regions; other site
1133852009429	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133852009430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009431	dimer interface [polypeptide binding]; other site
1133852009432	conserved gate region; other site
1133852009433	putative PBP binding loops; other site
1133852009434	ABC-ATPase subunit interface; other site
1133852009435	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1133852009436	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852009437	Walker A/P-loop; other site
1133852009438	ATP binding site [chemical binding]; other site
1133852009439	Q-loop/lid; other site
1133852009440	ABC transporter signature motif; other site
1133852009441	Walker B; other site
1133852009442	D-loop; other site
1133852009443	H-loop/switch region; other site
1133852009444	aminopeptidase N; Provisional; Region: pepN; PRK14015
1133852009445	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1133852009446	active site
1133852009447	Zn binding site [ion binding]; other site
1133852009448	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1133852009449	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1133852009450	active site
1133852009451	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1133852009452	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1133852009453	putative dimer interface [polypeptide binding]; other site
1133852009454	putative anticodon binding site; other site
1133852009455	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1133852009456	homodimer interface [polypeptide binding]; other site
1133852009457	motif 1; other site
1133852009458	motif 2; other site
1133852009459	active site
1133852009460	motif 3; other site
1133852009461	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133852009462	trimer interface [polypeptide binding]; other site
1133852009463	eyelet of channel; other site
1133852009464	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1133852009465	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852009466	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852009467	homodimer interface [polypeptide binding]; other site
1133852009468	catalytic residue [active]
1133852009469	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852009470	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852009471	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852009472	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1133852009473	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1133852009474	Peptidase M15; Region: Peptidase_M15_3; cl01194
1133852009475	murein L,D-transpeptidase; Provisional; Region: PRK10594
1133852009476	K+ potassium transporter; Region: K_trans; cl15781
1133852009477	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1133852009478	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133852009479	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1133852009480	MukB N-terminal; Region: MukB; pfam04310
1133852009481	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1133852009482	condesin subunit E; Provisional; Region: PRK05256
1133852009483	condesin subunit F; Provisional; Region: PRK05260
1133852009484	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133852009485	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852009486	S-adenosylmethionine binding site [chemical binding]; other site
1133852009487	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1133852009488	putative active site [active]
1133852009489	hypothetical protein; Provisional; Region: PRK10593
1133852009490	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1133852009491	Ligand binding site; other site
1133852009492	oligomer interface; other site
1133852009493	hypothetical protein; Provisional; Region: PRK11827
1133852009494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1133852009495	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1133852009496	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1133852009497	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852009498	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1133852009499	Walker A/P-loop; other site
1133852009500	ATP binding site [chemical binding]; other site
1133852009501	Q-loop/lid; other site
1133852009502	ABC transporter signature motif; other site
1133852009503	Walker B; other site
1133852009504	D-loop; other site
1133852009505	H-loop/switch region; other site
1133852009506	ComEC family competence protein; Provisional; Region: PRK11539
1133852009507	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1133852009508	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
1133852009509	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1133852009510	Beta subunit of integration host factor (IHFB); Region: IHF_B; cd13836
1133852009511	dimer interface [polypeptide binding]; other site
1133852009512	DNA binding site [nucleotide binding]
1133852009513	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1133852009514	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1133852009515	RNA binding site [nucleotide binding]; other site
1133852009516	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1133852009517	RNA binding site [nucleotide binding]; other site
1133852009518	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1133852009519	RNA binding site [nucleotide binding]; other site
1133852009520	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1133852009521	RNA binding site [nucleotide binding]; other site
1133852009522	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1133852009523	RNA binding site [nucleotide binding]; other site
1133852009524	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1133852009525	RNA binding site [nucleotide binding]; other site
1133852009526	cytidylate kinase; Provisional; Region: cmk; PRK00023
1133852009527	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1133852009528	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1133852009529	active site
1133852009530	CMP-binding site; other site
1133852009531	The sites determining sugar specificity; other site
1133852009532	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1133852009533	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1133852009534	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1133852009535	hinge; other site
1133852009536	active site
1133852009537	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1133852009538	homodimer interface [polypeptide binding]; other site
1133852009539	substrate-cofactor binding pocket; other site
1133852009540	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852009541	catalytic residue [active]
1133852009542	Predicted membrane protein [Function unknown]; Region: COG2323
1133852009543	uncharacterized domain; Region: TIGR00702
1133852009544	formate transporter; Provisional; Region: PRK10805
1133852009545	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1133852009546	Pyruvate formate lyase 1; Region: PFL1; cd01678
1133852009547	coenzyme A binding site [chemical binding]; other site
1133852009548	active site
1133852009549	catalytic residues [active]
1133852009550	glycine loop; other site
1133852009551	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1133852009552	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852009553	FeS/SAM binding site; other site
1133852009554	hypothetical protein; Provisional; Region: PRK09739
1133852009555	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852009556	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852009557	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1133852009558	putative effector binding pocket; other site
1133852009559	putative dimerization interface [polypeptide binding]; other site
1133852009560	Amino acid permease; Region: AA_permease_2; pfam13520
1133852009561	putative MFS family transporter protein; Provisional; Region: PRK03633
1133852009562	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852009563	putative substrate translocation pore; other site
1133852009564	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1133852009565	catalytic triad [active]
1133852009566	dimer interface [polypeptide binding]; other site
1133852009567	conserved cis-peptide bond; other site
1133852009568	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1133852009569	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1133852009570	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852009571	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1133852009572	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1133852009573	putative [Fe4-S4] binding site [ion binding]; other site
1133852009574	putative molybdopterin cofactor binding site [chemical binding]; other site
1133852009575	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1133852009576	putative molybdopterin cofactor binding site; other site
1133852009577	seryl-tRNA synthetase; Provisional; Region: PRK05431
1133852009578	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1133852009579	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1133852009580	dimer interface [polypeptide binding]; other site
1133852009581	active site
1133852009582	motif 1; other site
1133852009583	motif 2; other site
1133852009584	motif 3; other site
1133852009585	recombination factor protein RarA; Reviewed; Region: PRK13342
1133852009586	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852009587	Walker A motif; other site
1133852009588	ATP binding site [chemical binding]; other site
1133852009589	Walker B motif; other site
1133852009590	arginine finger; other site
1133852009591	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1133852009592	periplasmic chaperone LolA; Region: lolA; TIGR00547
1133852009593	DNA translocase FtsK; Provisional; Region: PRK10263
1133852009594	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1133852009595	hypothetical protein; Provisional; Region: PHA03160
1133852009596	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1133852009597	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1133852009598	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1133852009599	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1133852009600	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852009601	putative DNA binding site [nucleotide binding]; other site
1133852009602	putative Zn2+ binding site [ion binding]; other site
1133852009603	AsnC family; Region: AsnC_trans_reg; pfam01037
1133852009604	thioredoxin reductase; Provisional; Region: PRK10262
1133852009605	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852009606	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852009607	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1133852009608	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852009609	Alginate O-acetyl transferase AlgF; Region: AlgF; pfam11182
1133852009610	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852009611	Walker A/P-loop; other site
1133852009612	ATP binding site [chemical binding]; other site
1133852009613	Q-loop/lid; other site
1133852009614	ABC transporter signature motif; other site
1133852009615	Walker B; other site
1133852009616	D-loop; other site
1133852009617	H-loop/switch region; other site
1133852009618	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1133852009619	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852009620	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1133852009621	Walker A/P-loop; other site
1133852009622	ATP binding site [chemical binding]; other site
1133852009623	Q-loop/lid; other site
1133852009624	ABC transporter signature motif; other site
1133852009625	Walker B; other site
1133852009626	D-loop; other site
1133852009627	H-loop/switch region; other site
1133852009628	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1133852009629	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1133852009630	rRNA binding site [nucleotide binding]; other site
1133852009631	predicted 30S ribosome binding site; other site
1133852009632	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1133852009633	Clp amino terminal domain; Region: Clp_N; pfam02861
1133852009634	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852009635	Walker A motif; other site
1133852009636	ATP binding site [chemical binding]; other site
1133852009637	Walker B motif; other site
1133852009638	arginine finger; other site
1133852009639	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852009640	Walker A motif; other site
1133852009641	ATP binding site [chemical binding]; other site
1133852009642	Walker B motif; other site
1133852009643	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1133852009644	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1133852009645	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133852009646	DNA-binding site [nucleotide binding]; DNA binding site
1133852009647	RNA-binding motif; other site
1133852009648	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1133852009649	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133852009650	Walker A/P-loop; other site
1133852009651	ATP binding site [chemical binding]; other site
1133852009652	Q-loop/lid; other site
1133852009653	ABC transporter signature motif; other site
1133852009654	Walker B; other site
1133852009655	D-loop; other site
1133852009656	H-loop/switch region; other site
1133852009657	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133852009658	FtsX-like permease family; Region: FtsX; pfam02687
1133852009659	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1133852009660	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852009661	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852009662	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1133852009663	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1133852009664	AAA domain; Region: AAA_21; pfam13304
1133852009665	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1133852009666	putative active site [active]
1133852009667	putative metal-binding site [ion binding]; other site
1133852009668	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1133852009669	amphipathic channel; other site
1133852009670	Asn-Pro-Ala signature motifs; other site
1133852009671	Predicted membrane protein [Function unknown]; Region: COG2431
1133852009672	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1133852009673	cubane metal cluster [ion binding]; other site
1133852009674	hybrid metal cluster; other site
1133852009675	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1133852009676	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1133852009677	FAD binding pocket [chemical binding]; other site
1133852009678	FAD binding motif [chemical binding]; other site
1133852009679	phosphate binding motif [ion binding]; other site
1133852009680	beta-alpha-beta structure motif; other site
1133852009681	NAD binding pocket [chemical binding]; other site
1133852009682	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852009683	catalytic loop [active]
1133852009684	iron binding site [ion binding]; other site
1133852009685	pyruvate dehydrogenase; Provisional; Region: PRK09124
1133852009686	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1133852009687	PYR/PP interface [polypeptide binding]; other site
1133852009688	dimer interface [polypeptide binding]; other site
1133852009689	tetramer interface [polypeptide binding]; other site
1133852009690	TPP binding site [chemical binding]; other site
1133852009691	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133852009692	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1133852009693	TPP-binding site [chemical binding]; other site
1133852009694	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1133852009695	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
1133852009696	tetramer interface [polypeptide binding]; other site
1133852009697	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852009698	catalytic residue [active]
1133852009699	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1133852009700	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1133852009701	putative NAD(P) binding site [chemical binding]; other site
1133852009702	putative active site [active]
1133852009703	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1133852009704	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1133852009705	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1133852009706	NAD(P) binding site [chemical binding]; other site
1133852009707	active site
1133852009708	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1133852009709	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1133852009710	amidase catalytic site [active]
1133852009711	Zn binding residues [ion binding]; other site
1133852009712	substrate binding site [chemical binding]; other site
1133852009713	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
1133852009714	hypothetical protein; Provisional; Region: PRK02877
1133852009715	putative lipoprotein; Provisional; Region: PRK10533
1133852009716	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1133852009717	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852009718	Walker A/P-loop; other site
1133852009719	ATP binding site [chemical binding]; other site
1133852009720	Q-loop/lid; other site
1133852009721	ABC transporter signature motif; other site
1133852009722	Walker B; other site
1133852009723	D-loop; other site
1133852009724	H-loop/switch region; other site
1133852009725	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1133852009726	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852009727	substrate binding pocket [chemical binding]; other site
1133852009728	membrane-bound complex binding site; other site
1133852009729	hinge residues; other site
1133852009730	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1133852009731	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009732	dimer interface [polypeptide binding]; other site
1133852009733	conserved gate region; other site
1133852009734	putative PBP binding loops; other site
1133852009735	ABC-ATPase subunit interface; other site
1133852009736	arginine transporter permease subunit ArtM; Provisional; Region: artM; PRK11122
1133852009737	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009738	dimer interface [polypeptide binding]; other site
1133852009739	conserved gate region; other site
1133852009740	putative PBP binding loops; other site
1133852009741	ABC-ATPase subunit interface; other site
1133852009742	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1133852009743	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852009744	substrate binding pocket [chemical binding]; other site
1133852009745	membrane-bound complex binding site; other site
1133852009746	hinge residues; other site
1133852009747	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1133852009748	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852009749	S-adenosylmethionine binding site [chemical binding]; other site
1133852009750	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1133852009751	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1133852009752	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009753	dimer interface [polypeptide binding]; other site
1133852009754	conserved gate region; other site
1133852009755	putative PBP binding loops; other site
1133852009756	ABC-ATPase subunit interface; other site
1133852009757	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009758	dimer interface [polypeptide binding]; other site
1133852009759	conserved gate region; other site
1133852009760	putative PBP binding loops; other site
1133852009761	ABC-ATPase subunit interface; other site
1133852009762	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1133852009763	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852009764	Walker A/P-loop; other site
1133852009765	ATP binding site [chemical binding]; other site
1133852009766	Q-loop/lid; other site
1133852009767	ABC transporter signature motif; other site
1133852009768	Walker B; other site
1133852009769	D-loop; other site
1133852009770	H-loop/switch region; other site
1133852009771	TOBE domain; Region: TOBE_2; pfam08402
1133852009772	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1133852009773	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1133852009774	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1133852009775	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1133852009776	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1133852009777	dimer interface [polypeptide binding]; other site
1133852009778	FMN binding site [chemical binding]; other site
1133852009779	NADPH bind site [chemical binding]; other site
1133852009780	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1133852009781	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1133852009782	GSH binding site [chemical binding]; other site
1133852009783	catalytic residues [active]
1133852009784	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1133852009785	putative transporter; Provisional; Region: PRK04972
1133852009786	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1133852009787	TrkA-C domain; Region: TrkA_C; pfam02080
1133852009788	TrkA-C domain; Region: TrkA_C; pfam02080
1133852009789	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1133852009790	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1133852009791	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852009792	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1133852009793	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1133852009794	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852009795	putative substrate translocation pore; other site
1133852009796	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1133852009797	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852009798	active site
1133852009799	motif I; other site
1133852009800	motif II; other site
1133852009801	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852009802	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852009803	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1133852009804	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852009805	putative substrate translocation pore; other site
1133852009806	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1133852009807	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1133852009808	active site
1133852009809	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1133852009810	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852009811	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852009812	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1133852009813	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1133852009814	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1133852009815	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1133852009816	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1133852009817	putative C-terminal domain interface [polypeptide binding]; other site
1133852009818	putative GSH binding site (G-site) [chemical binding]; other site
1133852009819	putative dimer interface [polypeptide binding]; other site
1133852009820	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1133852009821	N-terminal domain interface [polypeptide binding]; other site
1133852009822	dimer interface [polypeptide binding]; other site
1133852009823	substrate binding pocket (H-site) [chemical binding]; other site
1133852009824	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; cl19645
1133852009825	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1133852009826	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1133852009827	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1133852009828	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1133852009829	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852009830	FeS/SAM binding site; other site
1133852009831	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852009832	metal binding site [ion binding]; metal-binding site
1133852009833	active site
1133852009834	I-site; other site
1133852009835	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852009836	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1133852009837	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1133852009838	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009839	dimer interface [polypeptide binding]; other site
1133852009840	conserved gate region; other site
1133852009841	putative PBP binding loops; other site
1133852009842	ABC-ATPase subunit interface; other site
1133852009843	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1133852009844	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009845	dimer interface [polypeptide binding]; other site
1133852009846	conserved gate region; other site
1133852009847	putative PBP binding loops; other site
1133852009848	ABC-ATPase subunit interface; other site
1133852009849	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1133852009850	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1133852009851	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1133852009852	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852009853	Walker A/P-loop; other site
1133852009854	ATP binding site [chemical binding]; other site
1133852009855	Q-loop/lid; other site
1133852009856	ABC transporter signature motif; other site
1133852009857	Walker B; other site
1133852009858	D-loop; other site
1133852009859	H-loop/switch region; other site
1133852009860	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852009861	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852009862	Walker A/P-loop; other site
1133852009863	ATP binding site [chemical binding]; other site
1133852009864	Q-loop/lid; other site
1133852009865	ABC transporter signature motif; other site
1133852009866	Walker B; other site
1133852009867	D-loop; other site
1133852009868	H-loop/switch region; other site
1133852009869	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1133852009870	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1133852009871	catalytic nucleophile [active]
1133852009872	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1133852009873	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1133852009874	dimer interface [polypeptide binding]; other site
1133852009875	putative functional site; other site
1133852009876	putative MPT binding site; other site
1133852009877	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1133852009878	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1133852009879	ATP binding site [chemical binding]; other site
1133852009880	substrate interface [chemical binding]; other site
1133852009881	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1133852009882	active site
1133852009883	intersubunit interactions; other site
1133852009884	catalytic residue [active]
1133852009885	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1133852009886	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
1133852009887	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
1133852009888	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1133852009889	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1133852009890	dimer interface [polypeptide binding]; other site
1133852009891	active site
1133852009892	glycine loop; other site
1133852009893	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1133852009894	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852009895	active site
1133852009896	motif I; other site
1133852009897	motif II; other site
1133852009898	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852009899	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1133852009900	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852009901	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852009902	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852009903	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1133852009904	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852009905	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852009906	Walker A/P-loop; other site
1133852009907	ATP binding site [chemical binding]; other site
1133852009908	ABC transporter signature motif; other site
1133852009909	Walker B; other site
1133852009910	ABC transporter; Region: ABC_tran_2; pfam12848
1133852009911	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852009912	L,D-transpeptidase; Provisional; Region: PRK10260
1133852009913	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133852009914	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1133852009915	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1133852009916	transmembrane helices; other site
1133852009917	manganese transport regulator MntR; Provisional; Region: PRK11050
1133852009918	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1133852009919	Iron dependent repressor, metal binding and dimerization domain; Region: Fe_dep_repr_C; pfam02742
1133852009920	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1133852009921	Sulfatase; Region: Sulfatase; pfam00884
1133852009922	outer membrane protein X; Provisional; Region: ompX; PRK09408
1133852009923	threonine and homoserine efflux system; Provisional; Region: PRK10532
1133852009924	EamA-like transporter family; Region: EamA; pfam00892
1133852009925	Ferritin-like domain; Region: Ferritin; pfam00210
1133852009926	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1133852009927	dimerization interface [polypeptide binding]; other site
1133852009928	DPS ferroxidase diiron center [ion binding]; other site
1133852009929	ion pore; other site
1133852009930	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1133852009931	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852009932	substrate binding pocket [chemical binding]; other site
1133852009933	membrane-bound complex binding site; other site
1133852009934	hinge residues; other site
1133852009935	glutamine ABC transporter permease protein; Reviewed; Region: glnP; PRK09494
1133852009936	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852009937	dimer interface [polypeptide binding]; other site
1133852009938	conserved gate region; other site
1133852009939	putative PBP binding loops; other site
1133852009940	ABC-ATPase subunit interface; other site
1133852009941	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1133852009942	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133852009943	Walker A/P-loop; other site
1133852009944	ATP binding site [chemical binding]; other site
1133852009945	Q-loop/lid; other site
1133852009946	ABC transporter signature motif; other site
1133852009947	Walker B; other site
1133852009948	D-loop; other site
1133852009949	H-loop/switch region; other site
1133852009950	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1133852009951	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133852009952	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1133852009953	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1133852009954	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
1133852009955	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852009956	N-terminal plug; other site
1133852009957	ligand-binding site [chemical binding]; other site
1133852009958	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
1133852009959	hypothetical protein; Provisional; Region: PRK11019
1133852009960	hypothetical protein; Provisional; Region: PRK10259
1133852009961	putative dehydrogenase; Provisional; Region: PRK10098
1133852009962	glycosyl transferase family protein; Provisional; Region: PRK08136
1133852009963	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1133852009964	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1133852009965	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1133852009966	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1133852009967	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
1133852009968	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1133852009969	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133852009970	ATP binding site [chemical binding]; other site
1133852009971	Mg++ binding site [ion binding]; other site
1133852009972	motif III; other site
1133852009973	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852009974	nucleotide binding region [chemical binding]; other site
1133852009975	ATP-binding site [chemical binding]; other site
1133852009976	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1133852009977	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852009978	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1133852009979	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1133852009980	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852009981	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852009982	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1133852009983	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133852009984	Walker A/P-loop; other site
1133852009985	ATP binding site [chemical binding]; other site
1133852009986	Q-loop/lid; other site
1133852009987	ABC transporter signature motif; other site
1133852009988	Walker B; other site
1133852009989	D-loop; other site
1133852009990	H-loop/switch region; other site
1133852009991	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1133852009992	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133852009993	Walker A/P-loop; other site
1133852009994	ATP binding site [chemical binding]; other site
1133852009995	Q-loop/lid; other site
1133852009996	ABC transporter signature motif; other site
1133852009997	Walker B; other site
1133852009998	D-loop; other site
1133852009999	H-loop/switch region; other site
1133852010000	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133852010001	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1133852010002	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133852010003	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1133852010004	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1133852010005	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1133852010006	putative catalytic site [active]
1133852010007	putative metal binding site [ion binding]; other site
1133852010008	putative phosphate binding site [ion binding]; other site
1133852010009	cardiolipin synthase 2; Provisional; Region: PRK11263
1133852010010	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1133852010011	putative active site [active]
1133852010012	catalytic site [active]
1133852010013	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1133852010014	putative active site [active]
1133852010015	catalytic site [active]
1133852010016	Predicted integral membrane protein [Function unknown]; Region: COG0392
1133852010017	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1133852010018	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1133852010019	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1133852010020	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1133852010021	MoaE homodimer interface [polypeptide binding]; other site
1133852010022	MoaD interaction [polypeptide binding]; other site
1133852010023	active site residues [active]
1133852010024	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1133852010025	MoaE interaction surface [polypeptide binding]; other site
1133852010026	MoeB interaction surface [polypeptide binding]; other site
1133852010027	thiocarboxylated glycine; other site
1133852010028	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1133852010029	trimer interface [polypeptide binding]; other site
1133852010030	dimer interface [polypeptide binding]; other site
1133852010031	putative active site [active]
1133852010032	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1133852010033	MPT binding site; other site
1133852010034	trimer interface [polypeptide binding]; other site
1133852010035	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1133852010036	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852010037	FeS/SAM binding site; other site
1133852010038	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1133852010039	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1133852010040	phosphate binding site [ion binding]; other site
1133852010041	putative substrate binding pocket [chemical binding]; other site
1133852010042	dimer interface [polypeptide binding]; other site
1133852010043	excinuclease ABC subunit B; Provisional; Region: PRK05298
1133852010044	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852010045	ATP binding site [chemical binding]; other site
1133852010046	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852010047	nucleotide binding region [chemical binding]; other site
1133852010048	ATP-binding site [chemical binding]; other site
1133852010049	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1133852010050	UvrB/uvrC motif; Region: UVR; pfam02151
1133852010051	AAA domain; Region: AAA_26; pfam13500
1133852010052	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
1133852010053	active site
1133852010054	ADP binding site [chemical binding]; other site
1133852010055	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1133852010056	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852010057	S-adenosylmethionine binding site [chemical binding]; other site
1133852010058	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
1133852010059	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1133852010060	substrate-cofactor binding pocket; other site
1133852010061	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852010062	catalytic residue [active]
1133852010063	biotin synthase; Provisional; Region: PRK15108
1133852010064	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852010065	FeS/SAM binding site; other site
1133852010066	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1133852010067	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1133852010068	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852010069	inhibitor-cofactor binding pocket; inhibition site
1133852010070	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852010071	catalytic residue [active]
1133852010072	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1133852010073	substrate binding site [chemical binding]; other site
1133852010074	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852010075	metal binding site [ion binding]; metal-binding site
1133852010076	active site
1133852010077	I-site; other site
1133852010078	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1133852010079	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852010080	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1133852010081	Phage Tail Collar Domain; Region: Collar; pfam07484
1133852010082	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1133852010083	Phage-related protein, tail component [Function unknown]; Region: COG4733
1133852010084	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1133852010085	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1133852010086	Interdomain contacts; other site
1133852010087	Cytokine receptor motif; other site
1133852010088	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1133852010089	Fibronectin type III protein; Region: DUF3672; pfam12421
1133852010090	Phage-related protein, tail component [Function unknown]; Region: COG4723
1133852010091	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1133852010092	MPN+ (JAMM) motif; other site
1133852010093	Zinc-binding site [ion binding]; other site
1133852010094	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133852010095	NlpC/P60 family; Region: NLPC_P60; cl17555
1133852010096	Phage-related protein [Function unknown]; Region: gp18; COG4672
1133852010097	Phage-related protein [Function unknown]; Region: COG4718
1133852010098	Phage-related minor tail protein [Function unknown]; Region: COG5281
1133852010099	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1133852010100	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1133852010101	Minor tail protein T; Region: Phage_tail_T; pfam06223
1133852010102	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1133852010103	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1133852010104	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1133852010105	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1133852010106	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1133852010107	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1133852010108	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1133852010109	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133852010110	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1133852010111	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1133852010112	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1133852010113	tandem repeat interface [polypeptide binding]; other site
1133852010114	oligomer interface [polypeptide binding]; other site
1133852010115	active site residues [active]
1133852010116	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1133852010117	gpW; Region: gpW; pfam02831
1133852010118	Phage terminase large subunit (GpA); Region: Terminase_GpA; cl19377
1133852010119	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1133852010120	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1133852010121	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1133852010122	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
1133852010123	KilA-N domain; Region: KilA-N; pfam04383
1133852010124	ORF11CD3 domain; Region: ORF11CD3; pfam10549
1133852010125	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
1133852010126	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1133852010127	catalytic residues [active]
1133852010128	Lysis protein S; Region: Lysis_S; pfam04971
1133852010129	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133852010130	trimer interface [polypeptide binding]; other site
1133852010131	eyelet of channel; other site
1133852010132	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1133852010133	Endodeoxyribonuclease RusA; Region: RusA; cl01885
1133852010134	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1133852010135	prophage protein NinE; Provisional; Region: PRK09689
1133852010136	hypothetical protein; Provisional; Region: PRK09741
1133852010137	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1133852010138	Recombinase; Region: Recombinase; pfam07508
1133852010139	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1133852010140	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1133852010141	acetyacetyl-CoA reductase; Provisional; Region: PRK12938
1133852010142	Replication protein P; Region: Phage_lambda_P; pfam06992
1133852010143	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1133852010144	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1133852010145	DNA-binding transcriptional regulator Cro; Region: P22_Cro; cl18770
1133852010146	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852010147	non-specific DNA binding site [nucleotide binding]; other site
1133852010148	salt bridge; other site
1133852010149	Predicted transcriptional regulator [Transcription]; Region: COG2932
1133852010150	sequence-specific DNA binding site [nucleotide binding]; other site
1133852010151	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852010152	Catalytic site [active]
1133852010153	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1133852010154	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
1133852010155	phage recombination protein Bet; Region: bet_lambda; TIGR01913
1133852010156	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1133852010157	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
1133852010158	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
1133852010159	DksA-like zinc finger domain containing protein; Region: PHA00080
1133852010160	Excisionase-like protein; Region: Exc; pfam07825
1133852010161	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1133852010162	Phage integrase, N-terminal SAM-like domain; Region: Phage_int_SAM_1; cl12235
1133852010163	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1133852010164	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1133852010165	dimer interface [polypeptide binding]; other site
1133852010166	active site
1133852010167	Int/Topo IB signature motif; other site
1133852010168	acyl-CoA thioesterase; Provisional; Region: PRK10531
1133852010169	Pectinesterase; Region: Pectinesterase; cl01911
1133852010170	putative hydratase; Provisional; Region: PRK11413
1133852010171	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1133852010172	substrate binding site [chemical binding]; other site
1133852010173	ligand binding site [chemical binding]; other site
1133852010174	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1133852010175	substrate binding site [chemical binding]; other site
1133852010176	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
1133852010177	anion transporter; Region: dass; TIGR00785
1133852010178	transmembrane helices; other site
1133852010179	PrpF protein; Region: PrpF; pfam04303
1133852010180	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852010181	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852010182	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1133852010183	putative dimerization interface [polypeptide binding]; other site
1133852010184	6-phosphogluconolactonase; Provisional; Region: PRK11028
1133852010185	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1133852010186	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852010187	active site
1133852010188	motif I; other site
1133852010189	motif II; other site
1133852010190	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852010191	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1133852010192	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852010193	Walker A/P-loop; other site
1133852010194	ATP binding site [chemical binding]; other site
1133852010195	Q-loop/lid; other site
1133852010196	ABC transporter signature motif; other site
1133852010197	Walker B; other site
1133852010198	D-loop; other site
1133852010199	H-loop/switch region; other site
1133852010200	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1133852010201	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1133852010202	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852010203	dimer interface [polypeptide binding]; other site
1133852010204	conserved gate region; other site
1133852010205	putative PBP binding loops; other site
1133852010206	ABC-ATPase subunit interface; other site
1133852010207	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852010208	substrate binding pocket [chemical binding]; other site
1133852010209	membrane-bound complex binding site; other site
1133852010210	hinge residues; other site
1133852010211	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1133852010212	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1133852010213	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1133852010214	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1133852010215	TOBE domain; Region: TOBE; pfam03459
1133852010216	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1133852010217	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1133852010218	Walker A/P-loop; other site
1133852010219	ATP binding site [chemical binding]; other site
1133852010220	Q-loop/lid; other site
1133852010221	ABC transporter signature motif; other site
1133852010222	Walker B; other site
1133852010223	D-loop; other site
1133852010224	H-loop/switch region; other site
1133852010225	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852010226	Walker A/P-loop; other site
1133852010227	ATP binding site [chemical binding]; other site
1133852010228	Q-loop/lid; other site
1133852010229	ABC transporter signature motif; other site
1133852010230	Walker B; other site
1133852010231	D-loop; other site
1133852010232	H-loop/switch region; other site
1133852010233	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1133852010234	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1133852010235	NAD binding site [chemical binding]; other site
1133852010236	homodimer interface [polypeptide binding]; other site
1133852010237	active site
1133852010238	substrate binding site [chemical binding]; other site
1133852010239	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1133852010240	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1133852010241	dimer interface [polypeptide binding]; other site
1133852010242	active site
1133852010243	galactokinase; Provisional; Region: PRK05101
1133852010244	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1133852010245	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1133852010246	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1133852010247	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1133852010248	active site
1133852010249	catalytic residues [active]
1133852010250	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133852010251	catalytic core [active]
1133852010252	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1133852010253	YbgS-like protein; Region: YbgS; pfam13985
1133852010254	zinc transporter ZitB; Provisional; Region: PRK03557
1133852010255	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1133852010256	quinolinate synthetase; Provisional; Region: PRK09375
1133852010257	tol-pal system protein YbgF; Provisional; Region: PRK10803
1133852010258	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1133852010259	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1133852010260	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1133852010261	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133852010262	ligand binding site [chemical binding]; other site
1133852010263	translocation protein TolB; Provisional; Region: tolB; PRK03629
1133852010264	TolB amino-terminal domain; Region: TolB_N; pfam04052
1133852010265	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1133852010266	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1133852010267	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1133852010268	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1133852010269	Double-stranded DNA-binding domain; Region: dsDNA_bind; cl00928
1133852010270	TolA C-terminal; Region: TolA; pfam06519
1133852010271	colicin uptake protein TolR; Provisional; Region: PRK11024
1133852010272	colicin uptake protein TolQ; Provisional; Region: PRK10801
1133852010273	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1133852010274	active site
1133852010275	hypothetical protein; Provisional; Region: PRK10588
1133852010276	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1133852010277	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1133852010278	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1133852010279	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1133852010280	alpha-mannosidase; Provisional; Region: PRK09819
1133852010281	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1133852010282	active site
1133852010283	metal binding site [ion binding]; metal-binding site
1133852010284	catalytic site [active]
1133852010285	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1133852010286	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
1133852010287	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1133852010288	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852010289	active site
1133852010290	phosphorylation site [posttranslational modification]
1133852010291	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133852010292	active site
1133852010293	P-loop; other site
1133852010294	phosphorylation site [posttranslational modification]
1133852010295	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1133852010296	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
1133852010297	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852010298	DNA-binding site [nucleotide binding]; DNA binding site
1133852010299	UTRA domain; Region: UTRA; pfam07702
1133852010300	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1133852010301	CoA binding domain; Region: CoA_binding; pfam02629
1133852010302	CoA-ligase; Region: Ligase_CoA; pfam00549
1133852010303	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1133852010304	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1133852010305	CoA-ligase; Region: Ligase_CoA; pfam00549
1133852010306	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1133852010307	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133852010308	E3 interaction surface; other site
1133852010309	lipoyl attachment site [posttranslational modification]; other site
1133852010310	e3 binding domain; Region: E3_binding; pfam02817
1133852010311	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1133852010312	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1133852010313	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1133852010314	TPP-binding site [chemical binding]; other site
1133852010315	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1133852010316	dimer interface [polypeptide binding]; other site
1133852010317	PYR/PP interface [polypeptide binding]; other site
1133852010318	TPP binding site [chemical binding]; other site
1133852010319	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1133852010320	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1133852010321	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1133852010322	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1133852010323	L-aspartate oxidase; Provisional; Region: PRK06175
1133852010324	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1133852010325	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1133852010326	SdhC subunit interface [polypeptide binding]; other site
1133852010327	proximal heme binding site [chemical binding]; other site
1133852010328	cardiolipin binding site; other site
1133852010329	Iron-sulfur protein interface; other site
1133852010330	proximal quinone binding site [chemical binding]; other site
1133852010331	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1133852010332	Iron-sulfur protein interface; other site
1133852010333	proximal quinone binding site [chemical binding]; other site
1133852010334	SdhD (CybS) interface [polypeptide binding]; other site
1133852010335	proximal heme binding site [chemical binding]; other site
1133852010336	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1133852010337	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1133852010338	dimer interface [polypeptide binding]; other site
1133852010339	active site
1133852010340	citrylCoA binding site [chemical binding]; other site
1133852010341	NADH binding [chemical binding]; other site
1133852010342	cationic pore residues; other site
1133852010343	oxalacetate/citrate binding site [chemical binding]; other site
1133852010344	coenzyme A binding site [chemical binding]; other site
1133852010345	catalytic triad [active]
1133852010346	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1133852010347	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852010348	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852010349	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852010350	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852010351	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852010352	Fimbrial protein; Region: Fimbrial; pfam00419
1133852010353	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1133852010354	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1133852010355	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1133852010356	endonuclease VIII; Provisional; Region: PRK10445
1133852010357	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1133852010358	DNA binding site [nucleotide binding]
1133852010359	catalytic residue [active]
1133852010360	putative catalytic residues [active]
1133852010361	H2TH interface [polypeptide binding]; other site
1133852010362	intercalation triad [nucleotide binding]; other site
1133852010363	substrate specificity determining residue; other site
1133852010364	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1133852010365	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1133852010366	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1133852010367	putative active site [active]
1133852010368	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
1133852010369	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
1133852010370	metal-binding protein; Provisional; Region: PRK10799
1133852010371	dipeptide/tripeptide permease D; Provisional; Region: PRK15462
1133852010372	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133852010373	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852010374	putative substrate translocation pore; other site
1133852010375	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1133852010376	DNA photolyase; Region: DNA_photolyase; pfam00875
1133852010377	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
1133852010378	hypothetical protein; Provisional; Region: PRK10167
1133852010379	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133852010380	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852010381	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133852010382	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133852010383	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010384	RHS protein; Region: RHS; pfam03527
1133852010385	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852010386	PAAR motif; Region: PAAR_motif; cl15808
1133852010387	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010388	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010389	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010390	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010391	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010392	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010393	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010394	RHS protein; Region: RHS; pfam03527
1133852010395	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852010396	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1133852010397	potassium-transporting ATPase subunit F; Provisional; Region: kdpF; PRK14748
1133852010398	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1133852010399	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1133852010400	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133852010401	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1133852010402	K+-transporting ATPase, c chain; Region: KdpC; pfam02669
1133852010403	sensor protein KdpD; Provisional; Region: PRK10490
1133852010404	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1133852010405	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1133852010406	Ligand Binding Site [chemical binding]; other site
1133852010407	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1133852010408	GAF domain; Region: GAF_3; pfam13492
1133852010409	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852010410	dimer interface [polypeptide binding]; other site
1133852010411	phosphorylation site [posttranslational modification]
1133852010412	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852010413	ATP binding site [chemical binding]; other site
1133852010414	Mg2+ binding site [ion binding]; other site
1133852010415	G-X-G motif; other site
1133852010416	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1133852010417	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852010418	active site
1133852010419	phosphorylation site [posttranslational modification]
1133852010420	intermolecular recognition site; other site
1133852010421	dimerization interface [polypeptide binding]; other site
1133852010422	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852010423	DNA binding site [nucleotide binding]
1133852010424	ornithine decarboxylase; Provisional; Region: PRK13578
1133852010425	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133852010426	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133852010427	homodimer interface [polypeptide binding]; other site
1133852010428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852010429	catalytic residue [active]
1133852010430	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133852010431	putrescine transporter; Provisional; Region: potE; PRK10655
1133852010432	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1133852010433	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1133852010434	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1133852010435	active site
1133852010436	substrate binding site [chemical binding]; other site
1133852010437	metal binding site [ion binding]; metal-binding site
1133852010438	replication initiation regulator SeqA; Provisional; Region: PRK11187
1133852010439	acyl-CoA esterase; Provisional; Region: PRK10673
1133852010440	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1133852010441	LexA regulated protein; Provisional; Region: PRK11675
1133852010442	flavodoxin FldA; Validated; Region: PRK09267
1133852010443	ryhB-regulated fur leader peptide; Provisional; Region: PRK14761
1133852010444	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1133852010445	metal binding site 2 [ion binding]; metal-binding site
1133852010446	putative DNA binding helix; other site
1133852010447	metal binding site 1 [ion binding]; metal-binding site
1133852010448	dimer interface [polypeptide binding]; other site
1133852010449	structural Zn2+ binding site [ion binding]; other site
1133852010450	YbfN-like lipoprotein; Region: YbfN; pfam13982
1133852010451	outer membrane porin, OprD family; Region: OprD; pfam03573
1133852010452	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1133852010453	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1133852010454	active site
1133852010455	HIGH motif; other site
1133852010456	KMSKS motif; other site
1133852010457	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1133852010458	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1133852010459	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133852010460	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852010461	active site turn [active]
1133852010462	phosphorylation site [posttranslational modification]
1133852010463	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1133852010464	HPr interaction site; other site
1133852010465	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1133852010466	active site
1133852010467	phosphorylation site [posttranslational modification]
1133852010468	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1133852010469	active site
1133852010470	trimer interface [polypeptide binding]; other site
1133852010471	allosteric site; other site
1133852010472	active site lid [active]
1133852010473	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1133852010474	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1133852010475	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1133852010476	active site
1133852010477	dimer interface [polypeptide binding]; other site
1133852010478	MarR family; Region: MarR_2; cl17246
1133852010479	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133852010480	ROK family; Region: ROK; pfam00480
1133852010481	UMP phosphatase; Provisional; Region: PRK10444
1133852010482	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852010483	active site
1133852010484	motif I; other site
1133852010485	motif II; other site
1133852010486	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1133852010487	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1133852010488	active site
1133852010489	dimer interface [polypeptide binding]; other site
1133852010490	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1133852010491	Ligand Binding Site [chemical binding]; other site
1133852010492	Molecular Tunnel; other site
1133852010493	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1133852010494	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1133852010495	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1133852010496	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1133852010497	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852010498	FeS/SAM binding site; other site
1133852010499	TRAM domain; Region: TRAM; pfam01938
1133852010500	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1133852010501	PhoH-like protein; Region: PhoH; pfam02562
1133852010502	metal-binding heat shock protein; Provisional; Region: PRK00016
1133852010503	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1133852010504	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133852010505	Transporter associated domain; Region: CorC_HlyC; smart01091
1133852010506	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1133852010507	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1133852010508	putative active site [active]
1133852010509	catalytic triad [active]
1133852010510	putative dimer interface [polypeptide binding]; other site
1133852010511	potential frameshift: common BLAST hit: gi|260866804|ref|YP_003233206.1| rhomboid family protein
1133852010512	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1133852010513	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852010514	substrate binding pocket [chemical binding]; other site
1133852010515	membrane-bound complex binding site; other site
1133852010516	hinge residues; other site
1133852010517	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
1133852010518	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852010519	dimer interface [polypeptide binding]; other site
1133852010520	conserved gate region; other site
1133852010521	putative PBP binding loops; other site
1133852010522	ABC-ATPase subunit interface; other site
1133852010523	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
1133852010524	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852010525	dimer interface [polypeptide binding]; other site
1133852010526	conserved gate region; other site
1133852010527	putative PBP binding loops; other site
1133852010528	ABC-ATPase subunit interface; other site
1133852010529	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1133852010530	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1133852010531	Walker A/P-loop; other site
1133852010532	ATP binding site [chemical binding]; other site
1133852010533	Q-loop/lid; other site
1133852010534	ABC transporter signature motif; other site
1133852010535	Walker B; other site
1133852010536	D-loop; other site
1133852010537	H-loop/switch region; other site
1133852010538	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1133852010539	active site
1133852010540	tetramer interface [polypeptide binding]; other site
1133852010541	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1133852010542	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1133852010543	nucleotide binding site [chemical binding]; other site
1133852010544	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1133852010545	SBD interface [polypeptide binding]; other site
1133852010546	DnaJ domain; Region: DnaJ; pfam00226
1133852010547	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1133852010548	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133852010549	Sel1-like repeats; Region: SEL1; smart00671
1133852010550	Sel1-like repeats; Region: SEL1; smart00671
1133852010551	Sel1-like repeats; Region: SEL1; smart00671
1133852010552	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133852010553	HSP70 interaction site [polypeptide binding]; other site
1133852010554	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1133852010555	Sel1-like repeats; Region: SEL1; smart00671
1133852010556	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133852010557	Sel1-like repeats; Region: SEL1; smart00671
1133852010558	Sel1-like repeats; Region: SEL1; smart00671
1133852010559	Sel1-like repeats; Region: SEL1; smart00671
1133852010560	Sel1-like repeats; Region: SEL1; smart00671
1133852010561	Sel1-like repeats; Region: SEL1; smart00671
1133852010562	Sel1-like repeats; Region: SEL1; smart00671
1133852010563	hypothetical protein; Provisional; Region: PRK11032
1133852010564	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1133852010565	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1133852010566	active site
1133852010567	HIGH motif; other site
1133852010568	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1133852010569	KMSKS motif; other site
1133852010570	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1133852010571	tRNA binding surface [nucleotide binding]; other site
1133852010572	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1133852010573	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1133852010574	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1133852010575	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1133852010576	Processivity clamp loader gamma complex DNA pol III C-term; Region: DNA_pol3_delt_C; pfam14840
1133852010577	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1133852010578	active site
1133852010579	(T/H)XGH motif; other site
1133852010580	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133852010581	catalytic core [active]
1133852010582	ribosome-associated protein; Provisional; Region: PRK11538
1133852010583	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1133852010584	penicillin-binding protein 2; Provisional; Region: PRK10795
1133852010585	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
1133852010586	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1133852010587	cell wall shape-determining protein; Provisional; Region: PRK10794
1133852010588	rare lipoprotein A; Provisional; Region: PRK10672
1133852010589	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1133852010590	Sporulation related domain; Region: SPOR; pfam05036
1133852010591	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1133852010592	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1133852010593	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1133852010594	hypothetical protein; Provisional; Region: PRK04998
1133852010595	lipoate-protein ligase B; Provisional; Region: PRK14342
1133852010596	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1133852010597	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852010598	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852010599	dimerization interface [polypeptide binding]; other site
1133852010600	lipoyl synthase; Provisional; Region: PRK05481
1133852010601	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852010602	FeS/SAM binding site; other site
1133852010603	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1133852010604	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1133852010605	putative active site [active]
1133852010606	catalytic triad [active]
1133852010607	putative dimer interface [polypeptide binding]; other site
1133852010608	chromosome condensation membrane protein; Provisional; Region: PRK14196
1133852010609	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1133852010610	DNA-binding site [nucleotide binding]; DNA binding site
1133852010611	RNA-binding motif; other site
1133852010612	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1133852010613	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1133852010614	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
1133852010615	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1133852010616	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852010617	active site
1133852010618	phosphorylation site [posttranslational modification]
1133852010619	intermolecular recognition site; other site
1133852010620	dimerization interface [polypeptide binding]; other site
1133852010621	Transcriptional regulator; Region: CitT; pfam12431
1133852010622	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1133852010623	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
1133852010624	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852010625	putative active site [active]
1133852010626	heme pocket [chemical binding]; other site
1133852010627	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
1133852010628	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852010629	ATP binding site [chemical binding]; other site
1133852010630	Mg2+ binding site [ion binding]; other site
1133852010631	G-X-G motif; other site
1133852010632	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1133852010633	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1133852010634	putative active site [active]
1133852010635	(T/H)XGH motif; other site
1133852010636	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1133852010637	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1133852010638	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1133852010639	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1133852010640	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1133852010641	anion transporter; Region: dass; TIGR00785
1133852010642	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1133852010643	transmembrane helices; other site
1133852010644	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1133852010645	B1 nucleotide binding pocket [chemical binding]; other site
1133852010646	B2 nucleotide binding pocket [chemical binding]; other site
1133852010647	CAS motifs; other site
1133852010648	active site
1133852010649	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1133852010650	Rnk N-terminus; Region: Rnk_N; pfam14760
1133852010651	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1133852010652	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1133852010653	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852010654	NAD binding site [chemical binding]; other site
1133852010655	catalytic Zn binding site [ion binding]; other site
1133852010656	structural Zn binding site [ion binding]; other site
1133852010657	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852010658	Ligand Binding Site [chemical binding]; other site
1133852010659	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1133852010660	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1133852010661	catalytic residue [active]
1133852010662	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1133852010663	catalytic residues [active]
1133852010664	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852010665	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852010666	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1133852010667	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1133852010668	dimer interface [polypeptide binding]; other site
1133852010669	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1133852010670	catalytic triad [active]
1133852010671	peroxidatic and resolving cysteines [active]
1133852010672	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1133852010673	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1133852010674	dimerization domain [polypeptide binding]; other site
1133852010675	dimer interface [polypeptide binding]; other site
1133852010676	catalytic residues [active]
1133852010677	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1133852010678	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852010679	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852010680	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1133852010681	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1133852010682	Active Sites [active]
1133852010683	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1133852010684	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1133852010685	ParB-like nuclease domain; Region: ParBc; pfam02195
1133852010686	methionine aminotransferase; Validated; Region: PRK09082
1133852010687	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852010688	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852010689	homodimer interface [polypeptide binding]; other site
1133852010690	catalytic residue [active]
1133852010691	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1133852010692	putative active site [active]
1133852010693	metal binding site [ion binding]; metal-binding site
1133852010694	Uncharacterized small protein [Function unknown]; Region: COG2879
1133852010695	carbon starvation protein A; Provisional; Region: PRK15015
1133852010696	Carbon starvation protein CstA; Region: CstA; pfam02554
1133852010697	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1133852010698	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133852010699	CoenzymeA binding site [chemical binding]; other site
1133852010700	subunit interaction site [polypeptide binding]; other site
1133852010701	PHB binding site; other site
1133852010702	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1133852010703	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1133852010704	putative NAD(P) binding site [chemical binding]; other site
1133852010705	active site
1133852010706	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1133852010707	hydrophobic substrate binding pocket; other site
1133852010708	active site
1133852010709	conserved cis-peptide bond; other site
1133852010710	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1133852010711	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1133852010712	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1133852010713	acyl-activating enzyme (AAE) consensus motif; other site
1133852010714	active site
1133852010715	AMP binding site [chemical binding]; other site
1133852010716	substrate binding site [chemical binding]; other site
1133852010717	isochorismate synthase EntC; Provisional; Region: PRK15016
1133852010718	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1133852010719	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
1133852010720	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1133852010721	siderophore binding site; other site
1133852010722	enterobactin exporter EntS; Provisional; Region: PRK10489
1133852010723	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852010724	putative substrate translocation pore; other site
1133852010725	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852010726	ABC-ATPase subunit  interface; other site
1133852010727	dimer interface [polypeptide binding]; other site
1133852010728	putative PBP binding regions; other site
1133852010729	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852010730	ABC-ATPase subunit  interface; other site
1133852010731	dimer interface [polypeptide binding]; other site
1133852010732	putative PBP binding regions; other site
1133852010733	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1133852010734	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133852010735	Walker A/P-loop; other site
1133852010736	ATP binding site [chemical binding]; other site
1133852010737	Q-loop/lid; other site
1133852010738	ABC transporter signature motif; other site
1133852010739	Walker B; other site
1133852010740	D-loop; other site
1133852010741	H-loop/switch region; other site
1133852010742	LPS O-antigen length regulator; Provisional; Region: PRK10381
1133852010743	Chain length determinant protein; Region: Wzz; pfam02706
1133852010744	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133852010745	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1133852010746	Condensation domain; Region: Condensation; cl19241
1133852010747	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1133852010748	acyl-activating enzyme (AAE) consensus motif; other site
1133852010749	AMP binding site [chemical binding]; other site
1133852010750	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1133852010751	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1133852010752	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1133852010753	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1133852010754	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1133852010755	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
1133852010756	outer membrane receptor FepA; Provisional; Region: PRK13524
1133852010757	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852010758	N-terminal plug; other site
1133852010759	ligand-binding site [chemical binding]; other site
1133852010760	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1133852010761	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1133852010762	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1133852010763	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133852010764	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852010765	Hok/gef family; Region: HOK_GEF; pfam01848
1133852010766	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1133852010767	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852010768	Hok/gef family; Region: HOK_GEF; pfam01848
1133852010769	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1133852010770	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1133852010771	hypothetical protein; Provisional; Region: PRK10250
1133852010772	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1133852010773	dimer interface [polypeptide binding]; other site
1133852010774	FMN binding site [chemical binding]; other site
1133852010775	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1133852010776	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133852010777	phenylalanine transporter; Provisional; Region: PRK10249
1133852010778	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852010779	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1133852010780	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1133852010781	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852010782	periplasmic copper-binding protein; Provisional; Region: PRK09838
1133852010783	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1133852010784	Outer membrane efflux protein; Region: OEP; pfam02321
1133852010785	Outer membrane efflux protein; Region: OEP; pfam02321
1133852010786	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
1133852010787	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852010788	active site
1133852010789	phosphorylation site [posttranslational modification]
1133852010790	intermolecular recognition site; other site
1133852010791	dimerization interface [polypeptide binding]; other site
1133852010792	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852010793	DNA binding site [nucleotide binding]
1133852010794	sensor kinase CusS; Provisional; Region: PRK09835
1133852010795	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852010796	dimerization interface [polypeptide binding]; other site
1133852010797	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852010798	dimer interface [polypeptide binding]; other site
1133852010799	phosphorylation site [posttranslational modification]
1133852010800	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852010801	ATP binding site [chemical binding]; other site
1133852010802	Mg2+ binding site [ion binding]; other site
1133852010803	G-X-G motif; other site
1133852010804	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133852010805	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133852010806	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133852010807	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1133852010808	Uncharacterized conserved protein [Function unknown]; Region: COG5435
1133852010809	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010810	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1133852010811	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852010812	Metallopeptidase toxin 4; Region: Tox-MPTase4; pfam15640
1133852010813	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133852010814	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852010815	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133852010816	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133852010817	bacteriophage N4 adsorption protein B; Provisional; Region: PRK14716
1133852010818	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
1133852010819	active site
1133852010820	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1133852010821	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
1133852010822	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852010823	TPR motif; other site
1133852010824	binding surface
1133852010825	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
1133852010826	hypothetical protein; Provisional; Region: PRK09936
1133852010827	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133852010828	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852010829	potential protein location (hypothetical protein O3K_18820 [Escherichia coli O104:H4 str. 2011C-3493]) that overlaps RNA (tRNA-R)
1133852010830	transcriptional regulator FimZ; Provisional; Region: PRK09935
1133852010831	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852010832	active site
1133852010833	phosphorylation site [posttranslational modification]
1133852010834	intermolecular recognition site; other site
1133852010835	dimerization interface [polypeptide binding]; other site
1133852010836	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852010837	DNA binding residues [nucleotide binding]
1133852010838	dimerization interface [polypeptide binding]; other site
1133852010839	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1133852010840	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1133852010841	outer membrane usher protein FimD; Provisional; Region: PRK15198
1133852010842	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852010843	Outer membrane usher protein; Region: Usher; pfam00577
1133852010844	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852010845	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1133852010846	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852010847	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852010848	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1133852010849	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1133852010850	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1133852010851	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1133852010852	homodimer interface [polypeptide binding]; other site
1133852010853	NADP binding site [chemical binding]; other site
1133852010854	substrate binding site [chemical binding]; other site
1133852010855	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852010856	RNA binding surface [nucleotide binding]; other site
1133852010857	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1133852010858	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1133852010859	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1133852010860	active site
1133852010861	HIGH motif; other site
1133852010862	KMSKS motif; other site
1133852010863	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1133852010864	tRNA binding surface [nucleotide binding]; other site
1133852010865	anticodon binding site; other site
1133852010866	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1133852010867	substrate binding site [chemical binding]; other site
1133852010868	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1133852010869	putative active site [active]
1133852010870	putative metal binding site [ion binding]; other site
1133852010871	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1133852010872	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [Nucleotide transport and metabolism]; Region: PurK; COG0026
1133852010873	ATP-grasp domain; Region: ATP-grasp; pfam02222
1133852010874	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1133852010875	putative substrate binding site [chemical binding]; other site
1133852010876	nucleotide binding site [chemical binding]; other site
1133852010877	nucleotide binding site [chemical binding]; other site
1133852010878	homodimer interface [polypeptide binding]; other site
1133852010879	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1133852010880	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1133852010881	membrane protein FdrA; Validated; Region: PRK06091
1133852010882	CoA binding domain; Region: CoA_binding; pfam02629
1133852010883	CoA-ligase; Region: Ligase_CoA; pfam00549
1133852010884	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
1133852010885	allantoate amidohydrolase; Region: AllC; TIGR03176
1133852010886	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1133852010887	active site
1133852010888	metal binding site [ion binding]; metal-binding site
1133852010889	dimer interface [polypeptide binding]; other site
1133852010890	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1133852010891	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
1133852010892	Cupin domain; Region: Cupin_2; cl17218
1133852010893	glycerate kinase II; Provisional; Region: PRK09932
1133852010894	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1133852010895	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1133852010896	allantoinase; Provisional; Region: PRK08044
1133852010897	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1133852010898	active site
1133852010899	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
1133852010900	Na binding site [ion binding]; other site
1133852010901	substrate binding site [chemical binding]; other site
1133852010902	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1133852010903	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
1133852010904	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
1133852010905	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1133852010906	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
1133852010907	glyoxylate carboligase; Provisional; Region: PRK11269
1133852010908	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133852010909	PYR/PP interface [polypeptide binding]; other site
1133852010910	dimer interface [polypeptide binding]; other site
1133852010911	TPP binding site [chemical binding]; other site
1133852010912	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133852010913	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1133852010914	TPP-binding site [chemical binding]; other site
1133852010915	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1133852010916	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133852010917	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133852010918	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1133852010919	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1133852010920	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852010921	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852010922	dimerization interface [polypeptide binding]; other site
1133852010923	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1133852010924	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1133852010925	active site residue [active]
1133852010926	Winged helix-turn helix; Region: HTH_29; pfam13551
1133852010927	Helix-turn-helix domain; Region: HTH_28; pfam13518
1133852010928	hypothetical protein; Provisional; Region: PRK14710
1133852010929	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010930	RHS protein; Region: RHS; pfam03527
1133852010931	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852010932	Serum amyloid A protein; Region: SAA; cl02506
1133852010933	NTF2 fold immunity protein; Region: Imm-NTF2-2; pfam15631
1133852010934	PAAR motif; Region: PAAR_motif; cl15808
1133852010935	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010936	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010937	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010938	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010939	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010940	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852010941	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010942	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1133852010943	RHS Repeat; Region: RHS_repeat; pfam05593
1133852010944	Erythromycin esterase; Region: Erythro_esteras; cl17110
1133852010945	RHS protein; Region: RHS; pfam03527
1133852010946	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852010947	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1133852010948	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1133852010949	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1133852010950	FtsX-like permease family; Region: FtsX; pfam02687
1133852010951	FtsX-like permease family; Region: FtsX; pfam02687
1133852010952	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1133852010953	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1133852010954	Walker A/P-loop; other site
1133852010955	ATP binding site [chemical binding]; other site
1133852010956	Q-loop/lid; other site
1133852010957	ABC transporter signature motif; other site
1133852010958	Walker B; other site
1133852010959	D-loop; other site
1133852010960	H-loop/switch region; other site
1133852010961	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1133852010962	active site
1133852010963	catalytic triad [active]
1133852010964	oxyanion hole [active]
1133852010965	switch loop; other site
1133852010966	short chain dehydrogenase; Validated; Region: PRK06182
1133852010967	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1133852010968	NADP binding site [chemical binding]; other site
1133852010969	active site
1133852010970	steroid binding site; other site
1133852010971	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1133852010972	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1133852010973	Tetratricopeptide repeat; Region: TPR_20; pfam14561
1133852010974	TIGR00245 family protein; Region: TIGR00245
1133852010975	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1133852010976	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852010977	Walker A/P-loop; other site
1133852010978	ATP binding site [chemical binding]; other site
1133852010979	Q-loop/lid; other site
1133852010980	ABC transporter signature motif; other site
1133852010981	Walker B; other site
1133852010982	D-loop; other site
1133852010983	H-loop/switch region; other site
1133852010984	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1133852010985	Paraslipin or slipin-2 (SLP-2, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_paraslipin; cd08829
1133852010986	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1133852010987	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1133852010988	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1133852010989	DNA binding residues [nucleotide binding]
1133852010990	dimer interface [polypeptide binding]; other site
1133852010991	copper binding site [ion binding]; other site
1133852010992	amino acid transporter; Region: 2A0306; TIGR00909
1133852010993	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1133852010994	glutaminase; Reviewed; Region: PRK12356
1133852010995	copper exporting ATPase; Provisional; Region: copA; PRK10671
1133852010996	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133852010997	metal-binding site [ion binding]
1133852010998	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1133852010999	metal-binding site [ion binding]
1133852011000	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133852011001	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852011002	motif II; other site
1133852011003	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852011004	sequence-specific DNA binding site [nucleotide binding]; other site
1133852011005	salt bridge; other site
1133852011006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1133852011007	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1133852011008	putative deacylase active site [active]
1133852011009	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1133852011010	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1133852011011	active site
1133852011012	metal binding site [ion binding]; metal-binding site
1133852011013	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1133852011014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011015	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852011016	putative substrate translocation pore; other site
1133852011017	putative cation:proton antiport protein; Provisional; Region: PRK10669
1133852011018	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1133852011019	TrkA-N domain; Region: TrkA_N; pfam02254
1133852011020	inosine/guanosine kinase; Provisional; Region: PRK15074
1133852011021	adenosine kinase; Provisional; Region: PTZ00247
1133852011022	substrate binding site [chemical binding]; other site
1133852011023	ATP binding site [chemical binding]; other site
1133852011024	acetyl esterase; Provisional; Region: PRK10162
1133852011025	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1133852011026	ferrochelatase; Region: hemH; TIGR00109
1133852011027	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1133852011028	C-terminal domain interface [polypeptide binding]; other site
1133852011029	active site
1133852011030	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1133852011031	active site
1133852011032	N-terminal domain interface [polypeptide binding]; other site
1133852011033	adenylate kinase; Reviewed; Region: adk; PRK00279
1133852011034	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1133852011035	AMP-binding site [chemical binding]; other site
1133852011036	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1133852011037	heat shock protein 90; Provisional; Region: PRK05218
1133852011038	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852011039	ATP binding site [chemical binding]; other site
1133852011040	Mg2+ binding site [ion binding]; other site
1133852011041	G-X-G motif; other site
1133852011042	Hsp90 protein; Region: HSP90; pfam00183
1133852011043	recombination protein RecR; Reviewed; Region: recR; PRK00076
1133852011044	RecR protein; Region: RecR; pfam02132
1133852011045	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1133852011046	putative active site [active]
1133852011047	putative metal-binding site [ion binding]; other site
1133852011048	tetramer interface [polypeptide binding]; other site
1133852011049	hypothetical protein; Validated; Region: PRK00153
1133852011050	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1133852011051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852011052	Walker A motif; other site
1133852011053	ATP binding site [chemical binding]; other site
1133852011054	Walker B motif; other site
1133852011055	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1133852011056	arginine finger; other site
1133852011057	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1133852011058	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1133852011059	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1133852011060	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852011061	active site
1133852011062	hypothetical protein; Provisional; Region: PRK10527
1133852011063	primosomal replication protein N''; Provisional; Region: PRK10093
1133852011064	hypothetical protein; Provisional; Region: PRK11038
1133852011065	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852011066	hypothetical protein; Provisional; Region: PRK11281
1133852011067	FSIP1 family; Region: FSIP1; pfam15554
1133852011068	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1133852011069	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133852011070	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1133852011071	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852011072	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1133852011073	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1133852011074	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1133852011075	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852011076	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1133852011077	MMPL family; Region: MMPL; cl14618
1133852011078	MMPL family; Region: MMPL; cl14618
1133852011079	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
1133852011080	gene expression modulator; Provisional; Region: PRK10945
1133852011081	maltose O-acetyltransferase; Provisional; Region: PRK10092
1133852011082	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1133852011083	active site
1133852011084	substrate binding site [chemical binding]; other site
1133852011085	trimer interface [polypeptide binding]; other site
1133852011086	CoA binding site [chemical binding]; other site
1133852011087	Inner membrane protein YlaC; Region: YlaC; pfam10777
1133852011088	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1133852011089	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133852011090	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852011091	Uncharacterized conserved protein [Function unknown]; Region: COG5507
1133852011092	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1133852011093	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1133852011094	DNA binding site [nucleotide binding]
1133852011095	active site
1133852011096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1133852011097	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1133852011098	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1133852011099	active site
1133852011100	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1133852011101	catalytic triad [active]
1133852011102	dimer interface [polypeptide binding]; other site
1133852011103	ammonium transporter; Provisional; Region: PRK10666
1133852011104	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1133852011105	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1133852011106	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852011107	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852011108	Walker A/P-loop; other site
1133852011109	ATP binding site [chemical binding]; other site
1133852011110	Q-loop/lid; other site
1133852011111	ABC transporter signature motif; other site
1133852011112	Walker B; other site
1133852011113	D-loop; other site
1133852011114	H-loop/switch region; other site
1133852011115	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1133852011116	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1133852011117	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852011118	Walker A/P-loop; other site
1133852011119	ATP binding site [chemical binding]; other site
1133852011120	Q-loop/lid; other site
1133852011121	ABC transporter signature motif; other site
1133852011122	Walker B; other site
1133852011123	D-loop; other site
1133852011124	H-loop/switch region; other site
1133852011125	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1133852011126	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852011127	putative DNA binding site [nucleotide binding]; other site
1133852011128	putative Zn2+ binding site [ion binding]; other site
1133852011129	AsnC family; Region: AsnC_trans_reg; pfam01037
1133852011130	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1133852011131	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852011132	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852011133	active site
1133852011134	motif I; other site
1133852011135	motif II; other site
1133852011136	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1133852011137	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1133852011138	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1133852011139	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1133852011140	Ligand Binding Site [chemical binding]; other site
1133852011141	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1133852011142	active site
1133852011143	DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair]; Region: ComEA; COG1555
1133852011144	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1133852011145	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1133852011146	periplasmic folding chaperone; Provisional; Region: PRK10788
1133852011147	SurA N-terminal domain; Region: SurA_N_3; cl07813
1133852011148	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1133852011149	histone-like DNA-binding protein HU; Region: HU; cd13831
1133852011150	dimer interface [polypeptide binding]; other site
1133852011151	DNA binding site [nucleotide binding]
1133852011152	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1133852011153	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
1133852011154	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852011155	Walker A motif; other site
1133852011156	ATP binding site [chemical binding]; other site
1133852011157	Walker B motif; other site
1133852011158	arginine finger; other site
1133852011159	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1133852011160	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1133852011161	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1133852011162	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852011163	Walker A motif; other site
1133852011164	ATP binding site [chemical binding]; other site
1133852011165	Walker B motif; other site
1133852011166	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133852011167	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1133852011168	oligomer interface [polypeptide binding]; other site
1133852011169	active site residues [active]
1133852011170	trigger factor; Provisional; Region: tig; PRK01490
1133852011171	Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697
1133852011172	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133852011173	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1133852011174	transcriptional regulator BolA; Provisional; Region: PRK11628
1133852011175	hypothetical protein; Provisional; Region: PRK11627
1133852011176	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011177	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852011178	putative substrate translocation pore; other site
1133852011179	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1133852011180	The cupredoxin domain of Ubiquinol oxidase subunit II; Region: CuRO_UO_II; cd04212
1133852011181	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1133852011182	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1133852011183	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1133852011184	D-pathway; other site
1133852011185	Putative ubiquinol binding site [chemical binding]; other site
1133852011186	Low-spin heme (heme b) binding site [chemical binding]; other site
1133852011187	Putative water exit pathway; other site
1133852011188	Binuclear center (heme o3/CuB) [ion binding]; other site
1133852011189	K-pathway; other site
1133852011190	Putative proton exit pathway; other site
1133852011191	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1133852011192	Subunit I/III interface [polypeptide binding]; other site
1133852011193	Subunit III/IV interface [polypeptide binding]; other site
1133852011194	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1133852011195	Protoheme IX farnesyltransferase; Region: PT_UbiA_Cox10; cd13957
1133852011196	putative active site [active]
1133852011197	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
1133852011198	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1133852011199	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133852011200	Sel1 repeat; Region: Sel1; pfam08238
1133852011201	Sel1-like repeats; Region: SEL1; smart00671
1133852011202	Sel1-like repeats; Region: SEL1; smart00671
1133852011203	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011204	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852011205	putative substrate translocation pore; other site
1133852011206	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1133852011207	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1133852011208	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1133852011209	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1133852011210	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1133852011211	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1133852011212	conserved cys residue [active]
1133852011213	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1133852011214	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1133852011215	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1133852011216	Ligand Binding Site [chemical binding]; other site
1133852011217	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1133852011218	active site residue [active]
1133852011219	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1133852011220	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1133852011221	substrate binding pocket [chemical binding]; other site
1133852011222	chain length determination region; other site
1133852011223	active site lid residues [active]
1133852011224	substrate-Mg2+ binding site; other site
1133852011225	catalytic residues [active]
1133852011226	aspartate-rich region 1; other site
1133852011227	aspartate-rich region 2; other site
1133852011228	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1133852011229	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1133852011230	TPP-binding site; other site
1133852011231	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1133852011232	PYR/PP interface [polypeptide binding]; other site
1133852011233	dimer interface [polypeptide binding]; other site
1133852011234	TPP binding site [chemical binding]; other site
1133852011235	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1133852011236	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852011237	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852011238	active site
1133852011239	catalytic tetrad [active]
1133852011240	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1133852011241	tetramer interfaces [polypeptide binding]; other site
1133852011242	binuclear metal-binding site [ion binding]; other site
1133852011243	thiamine monophosphate kinase; Provisional; Region: PRK05731
1133852011244	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1133852011245	ATP binding site [chemical binding]; other site
1133852011246	dimerization interface [polypeptide binding]; other site
1133852011247	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1133852011248	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1133852011249	homopentamer interface [polypeptide binding]; other site
1133852011250	active site
1133852011251	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1133852011252	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1133852011253	catalytic motif [active]
1133852011254	Zn binding site [ion binding]; other site
1133852011255	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1133852011256	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1133852011257	ATP cone domain; Region: ATP-cone; pfam03477
1133852011258	potential frameshift: common BLAST hit: gi|260866570|ref|YP_003232972.1| putative lipoprotein
1133852011259	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1133852011260	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852011261	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1133852011262	active site
1133852011263	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1133852011264	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1133852011265	Protein export membrane protein; Region: SecD_SecF; pfam02355
1133852011266	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1133852011267	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1133852011268	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1133852011269	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1133852011270	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1133852011271	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1133852011272	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1133852011273	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1133852011274	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1133852011275	maltodextrin glucosidase; Provisional; Region: PRK10785
1133852011276	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1133852011277	homodimer interface [polypeptide binding]; other site
1133852011278	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1133852011279	active site
1133852011280	homodimer interface [polypeptide binding]; other site
1133852011281	catalytic site [active]
1133852011282	putative proline-specific permease; Provisional; Region: proY; PRK10580
1133852011283	Spore germination protein; Region: Spore_permease; cl17796
1133852011284	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1133852011285	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1133852011286	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1133852011287	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852011288	putative active site [active]
1133852011289	heme pocket [chemical binding]; other site
1133852011290	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852011291	dimer interface [polypeptide binding]; other site
1133852011292	phosphorylation site [posttranslational modification]
1133852011293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852011294	ATP binding site [chemical binding]; other site
1133852011295	Mg2+ binding site [ion binding]; other site
1133852011296	G-X-G motif; other site
1133852011297	transcriptional regulator PhoB; Provisional; Region: PRK10161
1133852011298	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852011299	active site
1133852011300	phosphorylation site [posttranslational modification]
1133852011301	intermolecular recognition site; other site
1133852011302	dimerization interface [polypeptide binding]; other site
1133852011303	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852011304	DNA binding site [nucleotide binding]
1133852011305	exonuclease subunit SbcD; Provisional; Region: PRK10966
1133852011306	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1133852011307	active site
1133852011308	metal binding site [ion binding]; metal-binding site
1133852011309	DNA binding site [nucleotide binding]
1133852011310	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1133852011311	exonuclease subunit SbcC; Provisional; Region: PRK10246
1133852011312	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852011313	Walker A/P-loop; other site
1133852011314	ATP binding site [chemical binding]; other site
1133852011315	Q-loop/lid; other site
1133852011316	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852011317	ABC transporter signature motif; other site
1133852011318	Walker B; other site
1133852011319	D-loop; other site
1133852011320	H-loop/switch region; other site
1133852011321	MFS transport protein AraJ; Provisional; Region: PRK10091
1133852011322	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011323	putative substrate translocation pore; other site
1133852011324	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1133852011325	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852011326	nucleotide binding site [chemical binding]; other site
1133852011327	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1133852011328	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
1133852011329	hypothetical protein; Provisional; Region: PRK10579
1133852011330	hypothetical protein; Provisional; Region: PRK10481
1133852011331	hypothetical protein; Provisional; Region: PRK10380
1133852011332	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1133852011333	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1133852011334	ADP binding site [chemical binding]; other site
1133852011335	magnesium binding site [ion binding]; other site
1133852011336	putative shikimate binding site; other site
1133852011337	hypothetical protein; Validated; Region: PRK00124
1133852011338	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1133852011339	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1133852011340	Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748
1133852011341	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1133852011342	MASE2 domain; Region: MASE2; pfam05230
1133852011343	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1133852011344	metal binding site [ion binding]; metal-binding site
1133852011345	active site
1133852011346	I-site; other site
1133852011347	hypothetical protein; Provisional; Region: PRK11505
1133852011348	psiF repeat; Region: PsiF_repeat; pfam07769
1133852011349	psiF repeat; Region: PsiF_repeat; pfam07769
1133852011350	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
1133852011351	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1133852011352	dimer interface [polypeptide binding]; other site
1133852011353	active site
1133852011354	anti-RssB factor; Provisional; Region: PRK10244
1133852011355	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1133852011356	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1133852011357	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1133852011358	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1133852011359	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1133852011360	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1133852011361	microcin B17 transporter; Reviewed; Region: PRK11098
1133852011362	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1133852011363	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1133852011364	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1133852011365	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852011366	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852011367	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1133852011368	dimer interface [polypeptide binding]; other site
1133852011369	active site
1133852011370	Schiff base residues; other site
1133852011371	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1133852011372	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
1133852011373	active site
1133852011374	iron coordination sites [ion binding]; other site
1133852011375	substrate binding pocket [chemical binding]; other site
1133852011376	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1133852011377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852011378	dimer interface [polypeptide binding]; other site
1133852011379	conserved gate region; other site
1133852011380	putative PBP binding loops; other site
1133852011381	ABC-ATPase subunit interface; other site
1133852011382	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
1133852011383	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1133852011384	Walker A/P-loop; other site
1133852011385	ATP binding site [chemical binding]; other site
1133852011386	Q-loop/lid; other site
1133852011387	ABC transporter signature motif; other site
1133852011388	Walker B; other site
1133852011389	D-loop; other site
1133852011390	H-loop/switch region; other site
1133852011391	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1133852011392	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852011393	substrate binding pocket [chemical binding]; other site
1133852011394	membrane-bound complex binding site; other site
1133852011395	hinge residues; other site
1133852011396	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1133852011397	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1133852011398	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1133852011399	DXD motif; other site
1133852011400	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1133852011401	putative trimer interface [polypeptide binding]; other site
1133852011402	putative CoA binding site [chemical binding]; other site
1133852011403	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1133852011404	putative metal binding site [ion binding]; other site
1133852011405	putative homodimer interface [polypeptide binding]; other site
1133852011406	putative homotetramer interface [polypeptide binding]; other site
1133852011407	putative homodimer-homodimer interface [polypeptide binding]; other site
1133852011408	putative allosteric switch controlling residues; other site
1133852011409	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1133852011410	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1133852011411	substrate binding site [chemical binding]; other site
1133852011412	catalytic Zn binding site [ion binding]; other site
1133852011413	NAD binding site [chemical binding]; other site
1133852011414	structural Zn binding site [ion binding]; other site
1133852011415	dimer interface [polypeptide binding]; other site
1133852011416	Predicted esterase [General function prediction only]; Region: COG0627
1133852011417	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
1133852011418	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1133852011419	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
1133852011420	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011421	putative substrate translocation pore; other site
1133852011422	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
1133852011423	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
1133852011424	active site
1133852011425	catalytic residues [active]
1133852011426	metal binding site [ion binding]; metal-binding site
1133852011427	DmpG-like communication domain; Region: DmpG_comm; pfam07836
1133852011428	acetaldehyde dehydrogenase; Validated; Region: PRK08300
1133852011429	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
1133852011430	Prokaryotic acetaldehyde dehydrogenase, dimerization; Region: AcetDehyd-dimer; pfam09290
1133852011431	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
1133852011432	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
1133852011433	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1133852011434	Uncharacterized conserved protein (DUF2048); Region: DUF2048; pfam09752
1133852011435	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
1133852011436	putative active site [active]
1133852011437	Fe(II) binding site [ion binding]; other site
1133852011438	putative dimer interface [polypeptide binding]; other site
1133852011439	putative tetramer interface [polypeptide binding]; other site
1133852011440	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
1133852011441	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852011442	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
1133852011443	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133852011444	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133852011445	lac repressor; Reviewed; Region: lacI; PRK09526
1133852011446	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852011447	DNA binding site [nucleotide binding]
1133852011448	domain linker motif; other site
1133852011449	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1133852011450	ligand binding site [chemical binding]; other site
1133852011451	dimerization interface (open form) [polypeptide binding]; other site
1133852011452	dimerization interface (closed form) [polypeptide binding]; other site
1133852011453	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1133852011454	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1133852011455	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1133852011456	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1133852011457	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1133852011458	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1133852011459	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011460	putative substrate translocation pore; other site
1133852011461	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
1133852011462	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1133852011463	active site
1133852011464	substrate binding site [chemical binding]; other site
1133852011465	trimer interface [polypeptide binding]; other site
1133852011466	CoA binding site [chemical binding]; other site
1133852011467	putative cyanate transporter; Provisional; Region: cynX; PRK09705
1133852011468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852011469	putative substrate translocation pore; other site
1133852011470	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
1133852011471	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
1133852011472	oligomer interface [polypeptide binding]; other site
1133852011473	active site
1133852011474	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1133852011475	active site clefts [active]
1133852011476	zinc binding site [ion binding]; other site
1133852011477	dimer interface [polypeptide binding]; other site
1133852011478	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1133852011479	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852011480	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
1133852011481	dimerization interface [polypeptide binding]; other site
1133852011482	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
1133852011483	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1133852011484	active site
1133852011485	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1133852011486	Na binding site [ion binding]; other site
1133852011487	putative substrate binding site [chemical binding]; other site
1133852011488	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1133852011489	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
1133852011490	acyl-activating enzyme (AAE) consensus motif; other site
1133852011491	putative AMP binding site [chemical binding]; other site
1133852011492	putative active site [active]
1133852011493	putative CoA binding site [chemical binding]; other site
1133852011494	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1133852011495	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1133852011496	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1133852011497	dimer interface [polypeptide binding]; other site
1133852011498	active site
1133852011499	citrylCoA binding site [chemical binding]; other site
1133852011500	oxalacetate/citrate binding site [chemical binding]; other site
1133852011501	coenzyme A binding site [chemical binding]; other site
1133852011502	catalytic triad [active]
1133852011503	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1133852011504	tetramer interface [polypeptide binding]; other site
1133852011505	active site
1133852011506	Mg2+/Mn2+ binding site [ion binding]; other site
1133852011507	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1133852011508	Propionate catabolism activator; Region: PrpR_N; pfam06506
1133852011509	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852011510	Walker A motif; other site
1133852011511	ATP binding site [chemical binding]; other site
1133852011512	Walker B motif; other site
1133852011513	arginine finger; other site
1133852011514	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133852011515	hypothetical protein; Provisional; Region: PRK09929
1133852011516	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1133852011517	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1133852011518	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1133852011519	putative NAD(P) binding site [chemical binding]; other site
1133852011520	putative substrate binding site [chemical binding]; other site
1133852011521	catalytic Zn binding site [ion binding]; other site
1133852011522	structural Zn binding site [ion binding]; other site
1133852011523	dimer interface [polypeptide binding]; other site
1133852011524	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852011525	TM-ABC transporter signature motif; other site
1133852011526	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852011527	TM-ABC transporter signature motif; other site
1133852011528	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1133852011529	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852011530	Walker A/P-loop; other site
1133852011531	ATP binding site [chemical binding]; other site
1133852011532	Q-loop/lid; other site
1133852011533	ABC transporter signature motif; other site
1133852011534	Walker B; other site
1133852011535	D-loop; other site
1133852011536	H-loop/switch region; other site
1133852011537	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852011538	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1133852011539	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1133852011540	ligand binding site [chemical binding]; other site
1133852011541	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1133852011542	potential frameshift: common BLAST hit: gi|260866492|ref|YP_003232894.1| putative deaminase
1133852011543	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1133852011544	putative substrate binding site [chemical binding]; other site
1133852011545	nucleotide binding site [chemical binding]; other site
1133852011546	nucleotide binding site [chemical binding]; other site
1133852011547	homodimer interface [polypeptide binding]; other site
1133852011548	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1133852011549	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
1133852011550	CoA binding domain; Region: CoA_binding; pfam02629
1133852011551	CoA-ligase; Region: Ligase_CoA; pfam00549
1133852011552	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1133852011553	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1133852011554	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1133852011555	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1133852011556	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1133852011557	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1133852011558	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852011559	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852011560	dimerization interface [polypeptide binding]; other site
1133852011561	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852011562	DNA binding residues [nucleotide binding]
1133852011563	dimerization interface [polypeptide binding]; other site
1133852011564	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852011565	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852011566	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1133852011567	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852011568	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852011569	choline transport protein BetT; Provisional; Region: PRK09928
1133852011570	transcriptional regulator BetI; Validated; Region: PRK00767
1133852011571	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852011572	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1133852011573	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1133852011574	tetrameric interface [polypeptide binding]; other site
1133852011575	NAD binding site [chemical binding]; other site
1133852011576	catalytic residues [active]
1133852011577	choline dehydrogenase; Validated; Region: PRK02106
1133852011578	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852011579	GMC oxidoreductase; Region: GMC_oxred_N; pfam00732
1133852011580	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1133852011581	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133852011582	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1133852011583	iron-sulfur cluster-binding protein; Region: TIGR00273
1133852011584	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1133852011585	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1133852011586	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1133852011587	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1133852011588	Cysteine-rich domain; Region: CCG; pfam02754
1133852011589	Cysteine-rich domain; Region: CCG; pfam02754
1133852011590	Cupin; Region: Cupin_6; pfam12852
1133852011591	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1133852011592	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852011593	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852011594	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1133852011595	Squalene epoxidase; Region: SE; cl17314
1133852011596	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852011597	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1133852011598	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852011599	Predicted membrane protein [Function unknown]; Region: COG3059
1133852011600	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1133852011601	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852011602	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852011603	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1133852011604	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1133852011605	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133852011606	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133852011607	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133852011608	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1133852011609	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1133852011610	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1133852011611	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852011612	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852011613	DNA binding residues [nucleotide binding]
1133852011614	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1133852011615	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1133852011616	Outer membrane usher protein; Region: Usher; pfam00577
1133852011617	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1133852011618	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1133852011619	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
1133852011620	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
1133852011621	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1133852011622	catalytic loop [active]
1133852011623	iron binding site [ion binding]; other site
1133852011624	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1133852011625	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1133852011626	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
1133852011627	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1133852011628	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1133852011629	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1133852011630	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1133852011631	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1133852011632	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1133852011633	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1133852011634	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852011635	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852011636	Protein of unknown function (DUF4435); Region: DUF4435; pfam14491
1133852011637	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1133852011638	AAA ATPase domain; Region: AAA_15; pfam13175
1133852011639	Walker A/P-loop; other site
1133852011640	ATP binding site [chemical binding]; other site
1133852011641	AAA domain; Region: AAA_21; pfam13304
1133852011642	ABC transporter signature motif; other site
1133852011643	Walker B; other site
1133852011644	D-loop; other site
1133852011645	H-loop/switch region; other site
1133852011646	Helix-turn-helix domain; Region: HTH_17; cl17695
1133852011647	PerC transcriptional activator; Region: PerC; pfam06069
1133852011648	putative kissing complex interaction region; other site
1133852011649	putative RNA binding sites [nucleotide binding]; other site
1133852011650	ProQ/FINO family; Region: ProQ; pfam04352
1133852011651	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
1133852011652	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1133852011653	AntA/AntB antirepressor; Region: AntA; pfam08346
1133852011654	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1133852011655	Autophagy protein Apg6; Region: APG6; pfam04111
1133852011656	integrase; Provisional; Region: PRK09692
1133852011657	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852011658	active site
1133852011659	Int/Topo IB signature motif; other site
1133852011660	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1133852011661	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1133852011662	active site
1133852011663	DNA binding site [nucleotide binding]
1133852011664	Int/Topo IB signature motif; other site
1133852011665	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; cl01201
1133852011666	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1133852011667	DNA polymerase III psi subunit; Region: DNA_III_psi; cl11436
1133852011668	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1133852011669	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133852011670	catalytic residues [active]
1133852011671	catalytic nucleophile [active]
1133852011672	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133852011673	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133852011674	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133852011675	Synaptic Site I dimer interface [polypeptide binding]; other site
1133852011676	DNA binding site [nucleotide binding]
1133852011677	Homeodomain-like domain; Region: HTH_23; pfam13384
1133852011678	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1133852011679	putative catalytic cysteine [active]
1133852011680	gamma-glutamyl kinase; Provisional; Region: PRK05429
1133852011681	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1133852011682	nucleotide binding site [chemical binding]; other site
1133852011683	homotetrameric interface [polypeptide binding]; other site
1133852011684	putative phosphate binding site [ion binding]; other site
1133852011685	putative allosteric binding site; other site
1133852011686	PUA domain; Region: PUA; pfam01472
1133852011687	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1133852011688	trimer interface [polypeptide binding]; other site
1133852011689	eyelet of channel; other site
1133852011690	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1133852011691	Alpha/beta hydrolase of unknown function (DUF1100); Region: DUF1100; pfam06500
1133852011692	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1133852011693	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852011694	active site
1133852011695	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1133852011696	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1133852011697	metal binding site [ion binding]; metal-binding site
1133852011698	dimer interface [polypeptide binding]; other site
1133852011699	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1133852011700	putative peptide chain release factor H; Region: release_prfH; TIGR03072
1133852011701	hypothetical protein; Reviewed; Region: PRK09588
1133852011702	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
1133852011703	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133852011704	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852011705	Coenzyme A binding pocket [chemical binding]; other site
1133852011706	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1133852011707	active site
1133852011708	DNA polymerase IV; Validated; Region: PRK02406
1133852011709	DNA binding site [nucleotide binding]
1133852011710	hypothetical protein; Validated; Region: PRK06778
1133852011711	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1133852011712	ligand binding site [chemical binding]; other site
1133852011713	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
1133852011714	YcfA-like protein; Region: YcfA; pfam07927
1133852011715	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1133852011716	HicB family; Region: HicB; pfam05534
1133852011717	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133852011718	NlpC/P60 family; Region: NLPC_P60; pfam00877
1133852011719	RelB antitoxin; Region: RelB; pfam04221
1133852011720	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1133852011721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1133852011722	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1133852011723	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1133852011724	putative active site [active]
1133852011725	Glutamine amidotransferases class-II; Region: GATase_2; pfam00310
1133852011726	putative dimer interface [polypeptide binding]; other site
1133852011727	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1133852011728	dimer interface [polypeptide binding]; other site
1133852011729	active site
1133852011730	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1133852011731	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1133852011732	active site
1133852011733	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1133852011734	C-lysozyme inhibitor; Provisional; Region: PRK09993
1133852011735	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1133852011736	putative active site [active]
1133852011737	catalytic triad [active]
1133852011738	dimer interface [polypeptide binding]; other site
1133852011739	multimer interface [polypeptide binding]; other site
1133852011740	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1133852011741	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852011742	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133852011743	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1133852011744	potential frameshift: common BLAST hit: gi|291281062|ref|YP_003497880.1| transposase yncI
1133852011745	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852011746	RHS protein; Region: RHS; pfam03527
1133852011747	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852011748	PAAR motif; Region: PAAR_motif; cl15808
1133852011749	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011750	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011751	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011752	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011753	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852011754	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011755	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011756	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011757	RHS Repeat; Region: RHS_repeat; pfam05593
1133852011758	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1133852011759	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1133852011760	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1133852011761	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1133852011762	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1133852011763	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
1133852011764	Protein of unknown function (DUF877); Region: DUF877; cl05484
1133852011765	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1133852011766	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1133852011767	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1133852011768	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1133852011769	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
1133852011770	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1133852011771	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1133852011772	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1133852011773	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1133852011774	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852011775	Walker A motif; other site
1133852011776	ATP binding site [chemical binding]; other site
1133852011777	Walker B motif; other site
1133852011778	arginine finger; other site
1133852011779	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852011780	Walker A motif; other site
1133852011781	ATP binding site [chemical binding]; other site
1133852011782	Walker B motif; other site
1133852011783	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
1133852011784	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
1133852011785	ImpA-related N-terminal; Region: ImpA-rel_N; cl19907
1133852011786	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1133852011787	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1133852011788	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1133852011789	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
1133852011790	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1133852011791	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1133852011792	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1133852011793	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1133852011794	ImpA domain protein; Region: DUF3702; pfam12486
1133852011795	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1133852011796	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1133852011797	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1133852011798	active site
1133852011799	catalytic site [active]
1133852011800	substrate binding site [chemical binding]; other site
1133852011801	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1133852011802	RNA/DNA hybrid binding site [nucleotide binding]; other site
1133852011803	active site
1133852011804	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852011805	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1133852011806	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1133852011807	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852011808	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852011809	catalytic residue [active]
1133852011810	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852011811	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1133852011812	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1133852011813	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852011814	S-adenosylmethionine binding site [chemical binding]; other site
1133852011815	hypothetical protein; Provisional; Region: PRK05421
1133852011816	putative catalytic site [active]
1133852011817	putative metal binding site [ion binding]; other site
1133852011818	putative phosphate binding site [ion binding]; other site
1133852011819	putative catalytic site [active]
1133852011820	putative phosphate binding site [ion binding]; other site
1133852011821	putative metal binding site [ion binding]; other site
1133852011822	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1133852011823	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852011824	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1133852011825	putative effector binding pocket; other site
1133852011826	dimerization interface [polypeptide binding]; other site
1133852011827	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1133852011828	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1133852011829	active site
1133852011830	catalytic tetrad [active]
1133852011831	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1133852011832	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852011833	active site
1133852011834	motif I; other site
1133852011835	motif II; other site
1133852011836	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1133852011837	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1133852011838	Walker A/P-loop; other site
1133852011839	ATP binding site [chemical binding]; other site
1133852011840	Q-loop/lid; other site
1133852011841	ABC transporter signature motif; other site
1133852011842	Walker B; other site
1133852011843	D-loop; other site
1133852011844	H-loop/switch region; other site
1133852011845	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1133852011846	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852011847	dimer interface [polypeptide binding]; other site
1133852011848	conserved gate region; other site
1133852011849	putative PBP binding loops; other site
1133852011850	ABC-ATPase subunit interface; other site
1133852011851	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1133852011852	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1133852011853	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1133852011854	homodimer interaction site [polypeptide binding]; other site
1133852011855	cofactor binding site; other site
1133852011856	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1133852011857	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1133852011858	dimer interface [polypeptide binding]; other site
1133852011859	motif 1; other site
1133852011860	active site
1133852011861	motif 2; other site
1133852011862	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1133852011863	putative deacylase active site [active]
1133852011864	motif 3; other site
1133852011865	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1133852011866	anticodon binding site; other site
1133852011867	NlpC/P60 family; Region: NLPC_P60; cl17555
1133852011868	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1133852011869	NlpC/P60 family; Region: NLPC_P60; cl17555
1133852011870	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852011871	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852011872	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852011873	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1133852011874	Uncharacterized lipoprotein NlpE involved in copper resistance [Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism]; Region: CutF; COG3015
1133852011875	hypothetical protein; Provisional; Region: PRK09256
1133852011876	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1133852011877	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1133852011878	hypothetical protein; Provisional; Region: PRK04964
1133852011879	Rho-binding antiterminator; Provisional; Region: PRK11625
1133852011880	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1133852011881	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1133852011882	Ligand Binding Site [chemical binding]; other site
1133852011883	TilS substrate binding domain; Region: TilS; pfam09179
1133852011884	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1133852011885	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1133852011886	putative metal binding site [ion binding]; other site
1133852011887	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1133852011888	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133852011889	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133852011890	homodimer interface [polypeptide binding]; other site
1133852011891	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852011892	catalytic residue [active]
1133852011893	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133852011894	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1133852011895	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1133852011896	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1133852011897	putative active site [active]
1133852011898	putative PHP Thumb interface [polypeptide binding]; other site
1133852011899	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
1133852011900	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
1133852011901	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1133852011902	generic binding surface II; other site
1133852011903	generic binding surface I; other site
1133852011904	Bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1133852011905	RNA/DNA hybrid binding site [nucleotide binding]; other site
1133852011906	active site
1133852011907	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1133852011908	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1133852011909	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1133852011910	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1133852011911	active site
1133852011912	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1133852011913	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1133852011914	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1133852011915	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1133852011916	trimer interface [polypeptide binding]; other site
1133852011917	active site
1133852011918	UDP-GlcNAc binding site [chemical binding]; other site
1133852011919	lipid binding site [chemical binding]; lipid-binding site
1133852011920	periplasmic chaperone; Provisional; Region: PRK10780
1133852011921	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1133852011922	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852011923	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852011924	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852011925	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852011926	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852011927	Surface antigen; Region: Bac_surface_Ag; pfam01103
1133852011928	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1133852011929	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1133852011930	active site
1133852011931	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1133852011932	protein binding site [polypeptide binding]; other site
1133852011933	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1133852011934	protein binding site [polypeptide binding]; other site
1133852011935	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1133852011936	putative substrate binding region [chemical binding]; other site
1133852011937	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1133852011938	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
1133852011939	active site
1133852011940	dimer interface [polypeptide binding]; other site
1133852011941	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
1133852011942	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1133852011943	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1133852011944	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1133852011945	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1133852011946	hinge region; other site
1133852011947	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1133852011948	putative nucleotide binding site [chemical binding]; other site
1133852011949	uridine monophosphate binding site [chemical binding]; other site
1133852011950	homohexameric interface [polypeptide binding]; other site
1133852011951	elongation factor Ts; Provisional; Region: tsf; PRK09377
1133852011952	UBA/TS-N domain; Region: UBA; pfam00627
1133852011953	Bacterial virulence factor haemolysin; Region: SMP_2; cl11479
1133852011954	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1133852011955	rRNA interaction site [nucleotide binding]; other site
1133852011956	S8 interaction site; other site
1133852011957	putative laminin-1 binding site; other site
1133852011958	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1133852011959	active site
1133852011960	PII uridylyl-transferase; Provisional; Region: PRK05007
1133852011961	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1133852011962	metal binding triad; other site
1133852011963	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1133852011964	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133852011965	Zn2+ binding site [ion binding]; other site
1133852011966	Mg2+ binding site [ion binding]; other site
1133852011967	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1133852011968	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1133852011969	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1133852011970	Tetrahydrodipicolinate N-succinyltransferase N-terminal; Region: THDPS_N_2; pfam14805
1133852011971	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1133852011972	trimer interface [polypeptide binding]; other site
1133852011973	active site
1133852011974	substrate binding site [chemical binding]; other site
1133852011975	CoA binding site [chemical binding]; other site
1133852011976	hypothetical protein; Provisional; Region: PRK13677
1133852011977	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1133852011978	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1133852011979	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1133852011980	serine endoprotease; Provisional; Region: PRK10942
1133852011981	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1133852011982	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133852011983	protein binding site [polypeptide binding]; other site
1133852011984	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1133852011985	protein binding site [polypeptide binding]; other site
1133852011986	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1133852011987	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1133852011988	Zn2+ binding site [ion binding]; other site
1133852011989	Mg2+ binding site [ion binding]; other site
1133852011990	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1133852011991	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1133852011992	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1133852011993	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1133852011994	cobalamin binding residues [chemical binding]; other site
1133852011995	putative BtuC binding residues; other site
1133852011996	dimer interface [polypeptide binding]; other site
1133852011997	hypothetical protein; Provisional; Region: PRK10578
1133852011998	UPF0126 domain; Region: UPF0126; pfam03458
1133852011999	UPF0126 domain; Region: UPF0126; pfam03458
1133852012000	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1133852012001	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1133852012002	Cl- selectivity filter; other site
1133852012003	Cl- binding residues [ion binding]; other site
1133852012004	pore gating glutamate residue; other site
1133852012005	dimer interface [polypeptide binding]; other site
1133852012006	H+/Cl- coupling transport residue; other site
1133852012007	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1133852012008	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1133852012009	inhibitor-cofactor binding pocket; inhibition site
1133852012010	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852012011	catalytic residue [active]
1133852012012	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1133852012013	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852012014	ABC-ATPase subunit  interface; other site
1133852012015	dimer interface [polypeptide binding]; other site
1133852012016	putative PBP binding regions; other site
1133852012017	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852012018	ABC-ATPase subunit  interface; other site
1133852012019	dimer interface [polypeptide binding]; other site
1133852012020	putative PBP binding regions; other site
1133852012021	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1133852012022	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1133852012023	siderophore binding site; other site
1133852012024	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1133852012025	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133852012026	Walker A/P-loop; other site
1133852012027	ATP binding site [chemical binding]; other site
1133852012028	Q-loop/lid; other site
1133852012029	ABC transporter signature motif; other site
1133852012030	Walker B; other site
1133852012031	D-loop; other site
1133852012032	H-loop/switch region; other site
1133852012033	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1133852012034	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852012035	N-terminal plug; other site
1133852012036	ligand-binding site [chemical binding]; other site
1133852012037	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1133852012038	Transmembrane domain of transglycosylase PBP1 at N-terminal; Region: PBP1_TM; pfam14812
1133852012039	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
1133852012040	Transglycosylase; Region: Transgly; pfam00912
1133852012041	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1133852012042	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1133852012043	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852012044	ATP binding site [chemical binding]; other site
1133852012045	putative Mg++ binding site [ion binding]; other site
1133852012046	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852012047	nucleotide binding region [chemical binding]; other site
1133852012048	ATP-binding site [chemical binding]; other site
1133852012049	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
1133852012050	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1133852012051	2'-5' RNA ligase; Provisional; Region: PRK15124
1133852012052	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1133852012053	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1133852012054	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1133852012055	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1133852012056	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1133852012057	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
1133852012058	active site
1133852012059	nucleotide binding site [chemical binding]; other site
1133852012060	HIGH motif; other site
1133852012061	KMSKS motif; other site
1133852012062	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1133852012063	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1133852012064	active site
1133852012065	NTP binding site [chemical binding]; other site
1133852012066	metal binding triad [ion binding]; metal-binding site
1133852012067	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1133852012068	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1133852012069	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1133852012070	catalytic center binding site [active]
1133852012071	ATP binding site [chemical binding]; other site
1133852012072	Fimbrial protein; Region: Fimbrial; cl01416
1133852012073	putative chaperone protein EcpD; Provisional; Region: PRK09926
1133852012074	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852012075	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852012076	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1133852012077	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852012078	Outer membrane usher protein; Region: Usher; pfam00577
1133852012079	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852012080	Fimbrial protein; Region: Fimbrial; cl01416
1133852012081	putative fimbrial protein StaE; Provisional; Region: PRK15263
1133852012082	putative fimbrial protein StaF; Provisional; Region: PRK15262
1133852012083	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
1133852012084	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1133852012085	oligomerization interface [polypeptide binding]; other site
1133852012086	active site
1133852012087	metal binding site [ion binding]; metal-binding site
1133852012088	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1133852012089	active site
1133852012090	ATP-binding site [chemical binding]; other site
1133852012091	pantoate-binding site; other site
1133852012092	HXXH motif; other site
1133852012093	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1133852012094	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133852012095	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1133852012096	tetramerization interface [polypeptide binding]; other site
1133852012097	active site
1133852012098	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1133852012099	putative active site [active]
1133852012100	putative metal binding site [ion binding]; other site
1133852012101	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1133852012102	active pocket/dimerization site; other site
1133852012103	active site
1133852012104	phosphorylation site [posttranslational modification]
1133852012105	inner membrane transport permease; Provisional; Region: PRK15066
1133852012106	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1133852012107	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1133852012108	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1133852012109	Walker A/P-loop; other site
1133852012110	ATP binding site [chemical binding]; other site
1133852012111	Q-loop/lid; other site
1133852012112	ABC transporter signature motif; other site
1133852012113	Walker B; other site
1133852012114	D-loop; other site
1133852012115	H-loop/switch region; other site
1133852012116	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1133852012117	active site clefts [active]
1133852012118	zinc binding site [ion binding]; other site
1133852012119	dimer interface [polypeptide binding]; other site
1133852012120	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1133852012121	active site
1133852012122	Glucose dehydrogenase [Carbohydrate transport and metabolism]; Region: Gcd; COG4993
1133852012123	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1133852012124	Trp docking motif [polypeptide binding]; other site
1133852012125	putative active site [active]
1133852012126	multicopper oxidase; Provisional; Region: PRK10965
1133852012127	The first Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_1_CueO_FtsP; cd04232
1133852012128	Domain 2 interface [polypeptide binding]; other site
1133852012129	Domain 3 interface [polypeptide binding]; other site
1133852012130	trinuclear Cu binding site [ion binding]; other site
1133852012131	The second Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_2_CueO_FtsP; cd13867
1133852012132	Domain 1 interface [polypeptide binding]; other site
1133852012133	Domain 3 interface [polypeptide binding]; other site
1133852012134	The third Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_3_CueO_FtsP; cd13890
1133852012135	Domain 2 interface [polypeptide binding]; other site
1133852012136	Domain 1 interface [polypeptide binding]; other site
1133852012137	Type 1 (T1) Cu binding site [ion binding]; other site
1133852012138	trinuclear Cu binding site [ion binding]; other site
1133852012139	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1133852012140	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852012141	S-adenosylmethionine binding site [chemical binding]; other site
1133852012142	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1133852012143	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3112
1133852012144	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1133852012145	Aconitate B N-terminal domain; Region: Aconitase_B_N; pfam11791
1133852012146	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1133852012147	substrate binding site [chemical binding]; other site
1133852012148	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1133852012149	substrate binding site [chemical binding]; other site
1133852012150	ligand binding site [chemical binding]; other site
1133852012151	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1133852012152	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
1133852012153	dimer interface [polypeptide binding]; other site
1133852012154	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1133852012155	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852012156	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852012157	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1133852012158	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1133852012159	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133852012160	E3 interaction surface; other site
1133852012161	lipoyl attachment site [posttranslational modification]; other site
1133852012162	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133852012163	E3 interaction surface; other site
1133852012164	lipoyl attachment site [posttranslational modification]; other site
1133852012165	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1133852012166	E3 interaction surface; other site
1133852012167	lipoyl attachment site [posttranslational modification]; other site
1133852012168	e3 binding domain; Region: E3_binding; pfam02817
1133852012169	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1133852012170	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1133852012171	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1133852012172	dimer interface [polypeptide binding]; other site
1133852012173	TPP-binding site [chemical binding]; other site
1133852012174	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1133852012175	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852012176	DNA-binding site [nucleotide binding]; DNA binding site
1133852012177	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852012178	aromatic amino acid transporter; Provisional; Region: PRK10238
1133852012179	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852012180	regulatory protein AmpE; Provisional; Region: PRK10987
1133852012181	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1133852012182	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1133852012183	amidase catalytic site [active]
1133852012184	Zn binding residues [ion binding]; other site
1133852012185	substrate binding site [chemical binding]; other site
1133852012186	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1133852012187	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1133852012188	dimerization interface [polypeptide binding]; other site
1133852012189	active site
1133852012190	putative major pilin subunit; Provisional; Region: PRK10574
1133852012191	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1133852012192	Pilin (bacterial filament); Region: Pilin; pfam00114
1133852012193	hypothetical protein; Provisional; Region: PRK10436
1133852012194	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1133852012195	Walker A motif; other site
1133852012196	ATP binding site [chemical binding]; other site
1133852012197	Walker B motif; other site
1133852012198	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1133852012199	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133852012200	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133852012201	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1133852012202	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1133852012203	active site
1133852012204	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1133852012205	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1133852012206	CoA-binding site [chemical binding]; other site
1133852012207	ATP-binding [chemical binding]; other site
1133852012208	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1133852012209	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1133852012210	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1133852012211	active site
1133852012212	8-oxo-dGMP binding site [chemical binding]; other site
1133852012213	nudix motif; other site
1133852012214	metal binding site [ion binding]; metal-binding site
1133852012215	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1133852012216	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1133852012217	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
1133852012218	SEC-C motif; Region: SEC-C; pfam02810
1133852012219	SecA regulator SecM; Provisional; Region: PRK02943
1133852012220	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1133852012221	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1133852012222	cell division protein FtsZ; Validated; Region: PRK09330
1133852012223	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1133852012224	nucleotide binding site [chemical binding]; other site
1133852012225	SulA interaction site; other site
1133852012226	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1133852012227	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1133852012228	Cell division protein FtsA; Region: FtsA; pfam14450
1133852012229	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1133852012230	Cell division protein FtsA; Region: FtsA; pfam14450
1133852012231	cell division protein FtsQ; Provisional; Region: PRK10775
1133852012232	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1133852012233	Cell division protein FtsQ; Region: FtsQ; pfam03799
1133852012234	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1133852012235	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1133852012236	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1133852012237	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1133852012238	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133852012239	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133852012240	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133852012241	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1133852012242	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1133852012243	active site
1133852012244	homodimer interface [polypeptide binding]; other site
1133852012245	cell division protein FtsW; Provisional; Region: PRK10774
1133852012246	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1133852012247	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133852012248	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133852012249	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1133852012250	Mg++ binding site [ion binding]; other site
1133852012251	putative catalytic motif [active]
1133852012252	putative substrate binding site [chemical binding]; other site
1133852012253	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1133852012254	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133852012255	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133852012256	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133852012257	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1133852012258	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133852012259	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133852012260	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133852012261	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1133852012262	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
1133852012263	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1133852012264	cell division protein FtsL; Provisional; Region: PRK10772
1133852012265	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1133852012266	mraZ protein; Region: TIGR00242
1133852012267	MraZ protein; Region: MraZ; pfam02381
1133852012268	MraZ protein; Region: MraZ; pfam02381
1133852012269	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1133852012270	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852012271	DNA binding site [nucleotide binding]
1133852012272	domain linker motif; other site
1133852012273	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1133852012274	dimerization interface [polypeptide binding]; other site
1133852012275	ligand binding site [chemical binding]; other site
1133852012276	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1133852012277	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1133852012278	putative valine binding site [chemical binding]; other site
1133852012279	dimer interface [polypeptide binding]; other site
1133852012280	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1133852012281	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1133852012282	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133852012283	PYR/PP interface [polypeptide binding]; other site
1133852012284	dimer interface [polypeptide binding]; other site
1133852012285	TPP binding site [chemical binding]; other site
1133852012286	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133852012287	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1133852012288	TPP-binding site [chemical binding]; other site
1133852012289	dimer interface [polypeptide binding]; other site
1133852012290	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1133852012291	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852012292	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1133852012293	putative substrate binding pocket [chemical binding]; other site
1133852012294	putative dimerization interface [polypeptide binding]; other site
1133852012295	leu operon leader peptide; Provisional; Region: PRK09925
1133852012296	2-isopropylmalate synthase; Validated; Region: PRK00915
1133852012297	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1133852012298	active site
1133852012299	catalytic residues [active]
1133852012300	metal binding site [ion binding]; metal-binding site
1133852012301	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1133852012302	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1133852012303	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1133852012304	substrate binding site [chemical binding]; other site
1133852012305	ligand binding site [chemical binding]; other site
1133852012306	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1133852012307	substrate binding site [chemical binding]; other site
1133852012308	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852012309	sugar efflux transporter; Region: 2A0120; TIGR00899
1133852012310	putative substrate translocation pore; other site
1133852012311	transcriptional regulator SgrR; Provisional; Region: PRK13626
1133852012312	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1133852012313	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1133852012314	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1133852012315	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1133852012316	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852012317	dimer interface [polypeptide binding]; other site
1133852012318	conserved gate region; other site
1133852012319	putative PBP binding loops; other site
1133852012320	ABC-ATPase subunit interface; other site
1133852012321	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852012322	dimer interface [polypeptide binding]; other site
1133852012323	conserved gate region; other site
1133852012324	putative PBP binding loops; other site
1133852012325	ABC-ATPase subunit interface; other site
1133852012326	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1133852012327	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1133852012328	Walker A/P-loop; other site
1133852012329	ATP binding site [chemical binding]; other site
1133852012330	Q-loop/lid; other site
1133852012331	ABC transporter signature motif; other site
1133852012332	Walker B; other site
1133852012333	D-loop; other site
1133852012334	H-loop/switch region; other site
1133852012335	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1133852012336	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1133852012337	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133852012338	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852012339	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852012340	ribulokinase; Provisional; Region: PRK04123
1133852012341	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1133852012342	N- and C-terminal domain interface [polypeptide binding]; other site
1133852012343	active site
1133852012344	MgATP binding site [chemical binding]; other site
1133852012345	catalytic site [active]
1133852012346	metal binding site [ion binding]; metal-binding site
1133852012347	carbohydrate binding site [chemical binding]; other site
1133852012348	homodimer interface [polypeptide binding]; other site
1133852012349	L-arabinose isomerase; Provisional; Region: PRK02929
1133852012350	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1133852012351	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1133852012352	trimer interface [polypeptide binding]; other site
1133852012353	putative substrate binding site [chemical binding]; other site
1133852012354	putative metal binding site [ion binding]; other site
1133852012355	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133852012356	intersubunit interface [polypeptide binding]; other site
1133852012357	active site
1133852012358	Zn2+ binding site [ion binding]; other site
1133852012359	DNA polymerase II; Reviewed; Region: PRK05762
1133852012360	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1133852012361	active site
1133852012362	catalytic site [active]
1133852012363	substrate binding site [chemical binding]; other site
1133852012364	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1133852012365	active site
1133852012366	metal-binding site
1133852012367	ATP-dependent helicase HepA; Validated; Region: PRK04914
1133852012368	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852012369	ATP binding site [chemical binding]; other site
1133852012370	putative Mg++ binding site [ion binding]; other site
1133852012371	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852012372	nucleotide binding region [chemical binding]; other site
1133852012373	ATP-binding site [chemical binding]; other site
1133852012374	RNA polymerase recycling family C-terminal; Region: RapA_C; pfam12137
1133852012375	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1133852012376	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1133852012377	active site
1133852012378	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1133852012379	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1133852012380	putative metal binding site [ion binding]; other site
1133852012381	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133852012382	HSP70 interaction site [polypeptide binding]; other site
1133852012383	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1133852012384	OstA-like protein; Region: OstA; pfam03968
1133852012385	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1133852012386	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1133852012387	SurA N-terminal domain; Region: SurA_N; pfam09312
1133852012388	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1133852012389	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1133852012390	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1133852012391	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1133852012392	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1133852012393	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1133852012394	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1133852012395	active site
1133852012396	metal binding site [ion binding]; metal-binding site
1133852012397	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1133852012398	folate binding site [chemical binding]; other site
1133852012399	NADP+ binding site [chemical binding]; other site
1133852012400	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1133852012401	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1133852012402	TrkA-N domain; Region: TrkA_N; pfam02254
1133852012403	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1133852012404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852012405	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1133852012406	putative substrate translocation pore; other site
1133852012407	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1133852012408	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852012409	putative oxidoreductase FixC; Provisional; Region: PRK10157
1133852012410	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1133852012411	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1133852012412	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1133852012413	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1133852012414	Ligand binding site [chemical binding]; other site
1133852012415	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1133852012416	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1133852012417	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1133852012418	active site
1133852012419	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1133852012420	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1133852012421	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1133852012422	acyl-activating enzyme (AAE) consensus motif; other site
1133852012423	putative AMP binding site [chemical binding]; other site
1133852012424	putative active site [active]
1133852012425	putative CoA binding site [chemical binding]; other site
1133852012426	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1133852012427	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852012428	substrate binding site [chemical binding]; other site
1133852012429	oxyanion hole (OAH) forming residues; other site
1133852012430	trimer interface [polypeptide binding]; other site
1133852012431	carnitine operon protein CaiE; Provisional; Region: PRK13627
1133852012432	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1133852012433	putative trimer interface [polypeptide binding]; other site
1133852012434	putative metal binding site [ion binding]; other site
1133852012435	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1133852012436	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1133852012437	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1133852012438	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1133852012439	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
1133852012440	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1133852012441	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1133852012442	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1133852012443	IMP binding site; other site
1133852012444	dimer interface [polypeptide binding]; other site
1133852012445	interdomain contacts; other site
1133852012446	partial ornithine binding site; other site
1133852012447	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1133852012448	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1133852012449	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1133852012450	catalytic site [active]
1133852012451	subunit interface [polypeptide binding]; other site
1133852012452	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1133852012453	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1133852012454	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1133852012455	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1133852012456	active site
1133852012457	tetramer interface [polypeptide binding]; other site
1133852012458	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944
1133852012459	Fe-S cluster binding site [ion binding]; other site
1133852012460	substrate binding site [chemical binding]; other site
1133852012461	catalytic site [active]
1133852012462	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1133852012463	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
1133852012464	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1133852012465	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1133852012466	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1133852012467	active site
1133852012468	HIGH motif; other site
1133852012469	KMSKS motif; other site
1133852012470	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1133852012471	tRNA binding surface [nucleotide binding]; other site
1133852012472	anticodon binding site; other site
1133852012473	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1133852012474	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1133852012475	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1133852012476	active site
1133852012477	Riboflavin kinase; Region: Flavokinase; smart00904
1133852012478	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1133852012479	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1133852012480	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1133852012481	Outer membrane usher protein; Region: Usher; pfam00577
1133852012482	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852012483	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1133852012484	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852012485	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1133852012486	putative dimerization interface [polypeptide binding]; other site
1133852012487	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1133852012488	Hok/gef family; Region: HOK_GEF; pfam01848
1133852012489	chaperone protein DnaJ; Provisional; Region: PRK10767
1133852012490	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1133852012491	HSP70 interaction site [polypeptide binding]; other site
1133852012492	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1133852012493	substrate binding site [polypeptide binding]; other site
1133852012494	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1133852012495	Zn binding sites [ion binding]; other site
1133852012496	dimer interface [polypeptide binding]; other site
1133852012497	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1133852012498	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
1133852012499	nucleotide binding site [chemical binding]; other site
1133852012500	NEF interaction site [polypeptide binding]; other site
1133852012501	SBD interface [polypeptide binding]; other site
1133852012502	hypothetical protein; Provisional; Region: PRK10154
1133852012503	hypothetical protein; Provisional; Region: PRK10236
1133852012504	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1133852012505	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1133852012506	hypothetical protein; Provisional; Region: PRK10659
1133852012507	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1133852012508	MPT binding site; other site
1133852012509	trimer interface [polypeptide binding]; other site
1133852012510	transaldolase-like protein; Provisional; Region: PTZ00411
1133852012511	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1133852012512	active site
1133852012513	dimer interface [polypeptide binding]; other site
1133852012514	catalytic residue [active]
1133852012515	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1133852012516	hypothetical protein; Validated; Region: PRK02101
1133852012517	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1133852012518	threonine synthase; Validated; Region: PRK09225
1133852012519	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1133852012520	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852012521	catalytic residue [active]
1133852012522	homoserine kinase; Region: thrB; TIGR00191
1133852012523	Protein of unknown function; Region: YhfT; pfam10797
1133852012524	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1133852012525	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1133852012526	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1133852012527	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1133852012528	putative catalytic residues [active]
1133852012529	putative nucleotide binding site [chemical binding]; other site
1133852012530	putative aspartate binding site [chemical binding]; other site
1133852012531	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1133852012532	dimer interface [polypeptide binding]; other site
1133852012533	putative threonine allosteric regulatory site; other site
1133852012534	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1133852012535	putative threonine allosteric regulatory site; other site
1133852012536	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1133852012537	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1133852012538	putative RNA methyltransferase; Provisional; Region: PRK10433
1133852012539	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
1133852012540	two-component response regulator; Provisional; Region: PRK11173
1133852012541	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852012542	active site
1133852012543	phosphorylation site [posttranslational modification]
1133852012544	intermolecular recognition site; other site
1133852012545	dimerization interface [polypeptide binding]; other site
1133852012546	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852012547	DNA binding site [nucleotide binding]
1133852012548	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1133852012549	sensory histidine kinase CreC; Provisional; Region: PRK11100
1133852012550	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852012551	dimerization interface [polypeptide binding]; other site
1133852012552	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852012553	dimer interface [polypeptide binding]; other site
1133852012554	phosphorylation site [posttranslational modification]
1133852012555	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852012556	ATP binding site [chemical binding]; other site
1133852012557	Mg2+ binding site [ion binding]; other site
1133852012558	G-X-G motif; other site
1133852012559	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1133852012560	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852012561	active site
1133852012562	phosphorylation site [posttranslational modification]
1133852012563	intermolecular recognition site; other site
1133852012564	dimerization interface [polypeptide binding]; other site
1133852012565	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852012566	DNA binding site [nucleotide binding]
1133852012567	hypothetical protein; Provisional; Region: PRK10756
1133852012568	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1133852012569	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852012570	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852012571	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1133852012572	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1133852012573	catalytic core [active]
1133852012574	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1133852012575	Trp operon repressor [Transcription]; Region: TrpR; COG2973
1133852012576	lytic murein transglycosylase; Provisional; Region: PRK11619
1133852012577	Soluble lytic murein transglycosylase L domain; Region: SLT_L; pfam14718
1133852012578	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852012579	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852012580	catalytic residue [active]
1133852012581	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1133852012582	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852012583	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
1133852012584	ABC transporter; Region: ABC_tran_2; pfam12848
1133852012585	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1133852012586	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852012587	non-specific DNA binding site [nucleotide binding]; other site
1133852012588	salt bridge; other site
1133852012589	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1133852012590	sequence-specific DNA binding site [nucleotide binding]; other site
1133852012591	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1133852012592	active site
1133852012593	(T/H)XGH motif; other site
1133852012594	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1133852012595	DNA repair protein RadA; Region: sms; TIGR00416
1133852012596	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1133852012597	Walker A motif/ATP binding site; other site
1133852012598	ATP binding site [chemical binding]; other site
1133852012599	Walker B motif; other site
1133852012600	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1133852012601	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1133852012602	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852012603	motif II; other site
1133852012604	hypothetical protein; Provisional; Region: PRK11246
1133852012605	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1133852012606	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1133852012607	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1133852012608	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1133852012609	phosphopentomutase; Provisional; Region: PRK05362
1133852012610	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1133852012611	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1133852012612	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1133852012613	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1133852012614	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1133852012615	intersubunit interface [polypeptide binding]; other site
1133852012616	active site
1133852012617	catalytic residue [active]
1133852012618	hypothetical protein; Provisional; Region: PRK10977
1133852012619	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1133852012620	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1133852012621	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852012622	FeS/SAM binding site; other site
1133852012623	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1133852012624	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1133852012625	active site
1133852012626	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1133852012627	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1133852012628	active site
1133852012629	nucleophile elbow; other site
1133852012630	Small integral membrane protein [Function unknown]; Region: COG5487
1133852012631	periplasmic protein; Provisional; Region: PRK10568
1133852012632	BON domain; Region: BON; pfam04972
1133852012633	BON domain; Region: BON; pfam04972
1133852012634	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1133852012635	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1133852012636	G1 box; other site
1133852012637	putative GEF interaction site [polypeptide binding]; other site
1133852012638	GTP/Mg2+ binding site [chemical binding]; other site
1133852012639	Switch I region; other site
1133852012640	G2 box; other site
1133852012641	G3 box; other site
1133852012642	Switch II region; other site
1133852012643	G4 box; other site
1133852012644	G5 box; other site
1133852012645	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1133852012646	Elongation Factor G, domain II; Region: EFG_II; pfam14492
1133852012647	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1133852012648	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852012649	motif II; other site
1133852012650	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1133852012651	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852012652	Coenzyme A binding pocket [chemical binding]; other site
1133852012653	DNA polymerase III, psi subunit [DNA replication, recombination, and repair]; Region: HolD; COG3050
1133852012654	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1133852012655	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1133852012656	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852012657	S-adenosylmethionine binding site [chemical binding]; other site
1133852012658	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1133852012659	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1133852012660	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1133852012661	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1133852012662	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1133852012663	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852012664	DNA binding residues [nucleotide binding]
1133852012665	dimerization interface [polypeptide binding]; other site
1133852012666	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1133852012667	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1133852012668	DNA binding residues [nucleotide binding]
1133852012669	dimerization interface [polypeptide binding]; other site
1133852012670	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1133852012671	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1133852012672	hypothetical protein; Provisional; Region: PRK09917
1133852012673	primosomal protein DnaI; Provisional; Region: PRK02854
1133852012674	DNA replication protein DnaC; Validated; Region: PRK07952
1133852012675	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852012676	Walker A motif; other site
1133852012677	ATP binding site [chemical binding]; other site
1133852012678	Walker B motif; other site
1133852012679	hypothetical protein; Provisional; Region: PRK11667
1133852012680	phosphoglycerol transferase I; Provisional; Region: PRK03776
1133852012681	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1133852012682	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852012683	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1133852012684	putative NAD(P) binding site [chemical binding]; other site
1133852012685	catalytic Zn binding site [ion binding]; other site
1133852012686	structural Zn binding site [ion binding]; other site
1133852012687	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1133852012688	DNA-binding site [nucleotide binding]; DNA binding site
1133852012689	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1133852012690	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1133852012691	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852012692	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852012693	D-galactonate transporter; Region: 2A0114; TIGR00893
1133852012694	putative substrate translocation pore; other site
1133852012695	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1133852012696	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1133852012697	dimer interface [polypeptide binding]; other site
1133852012698	ligand binding site [chemical binding]; other site
1133852012699	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852012700	dimerization interface [polypeptide binding]; other site
1133852012701	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1133852012702	dimer interface [polypeptide binding]; other site
1133852012703	putative CheW interface [polypeptide binding]; other site
1133852012704	carbon starvation protein A; Provisional; Region: PRK15015
1133852012705	Carbon starvation protein CstA; Region: CstA; pfam02554
1133852012706	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1133852012707	Uncharacterized small protein [Function unknown]; Region: COG2879
1133852012708	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1133852012709	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1133852012710	P-loop, Walker A motif; other site
1133852012711	Base recognition motif; other site
1133852012712	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1133852012713	Protein of unknown function DUF262; Region: DUF262; pfam03235
1133852012714	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1133852012715	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1133852012716	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1133852012717	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852012718	ATP binding site [chemical binding]; other site
1133852012719	putative Mg++ binding site [ion binding]; other site
1133852012720	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
1133852012721	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1133852012722	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1133852012723	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1133852012724	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1133852012725	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1133852012726	endoribonuclease SymE; Provisional; Region: PRK13605
1133852012727	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1133852012728	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1133852012729	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852012730	DNA-binding site [nucleotide binding]; DNA binding site
1133852012731	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852012732	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852012733	homodimer interface [polypeptide binding]; other site
1133852012734	catalytic residue [active]
1133852012735	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1133852012736	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133852012737	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1133852012738	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852012739	putative substrate translocation pore; other site
1133852012740	Predicted membrane protein [Function unknown]; Region: COG2733
1133852012741	Protein of unknown function (DUF445); Region: DUF445; pfam04286
1133852012742	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
1133852012743	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1133852012744	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
1133852012745	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1133852012746	SdiA-regulated; Region: SdiA-regulated; cd09971
1133852012747	putative active site [active]
1133852012748	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852012749	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852012750	putative substrate translocation pore; other site
1133852012751	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1133852012752	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1133852012753	Nucleoside recognition; Region: Gate; pfam07670
1133852012754	hypothetical protein; Provisional; Region: PRK10519
1133852012755	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
1133852012756	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
1133852012757	dimer interface [polypeptide binding]; other site
1133852012758	active site
1133852012759	cell density-dependent motility repressor; Provisional; Region: PRK10082
1133852012760	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852012761	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1133852012762	dimerization interface [polypeptide binding]; other site
1133852012763	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1133852012764	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
1133852012765	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1133852012766	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852012767	DNA-binding site [nucleotide binding]; DNA binding site
1133852012768	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852012769	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1133852012770	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1133852012771	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1133852012772	mannonate dehydratase; Region: uxuA; TIGR00695
1133852012773	mannonate dehydratase; Provisional; Region: PRK03906
1133852012774	fructuronate transporter; Provisional; Region: PRK10034
1133852012775	GntP family permease; Region: GntP_permease; pfam02447
1133852012776	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852012777	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852012778	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852012779	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852012780	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1133852012781	Haemolysin expression modulating protein; Region: HHA; pfam05321
1133852012782	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1133852012783	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852012784	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1133852012785	Transposase; Region: HTH_Tnp_1; pfam01527
1133852012786	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852012787	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852012788	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852012789	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
1133852012790	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133852012791	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852012792	zinc-finger binding domain of transposase IS66; Region: zf-IS66; pfam13005
1133852012793	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852012794	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852012795	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
1133852012796	SdiA-regulated; Region: SdiA-regulated; cl19046
1133852012797	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
1133852012798	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1133852012799	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1133852012800	DNA binding residues [nucleotide binding]
1133852012801	fec operon regulator FecR; Reviewed; Region: PRK09774
1133852012802	FecR protein; Region: FecR; pfam04773
1133852012803	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1133852012804	Secretin and TonB N terminus short domain; Region: STN; smart00965
1133852012805	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852012806	N-terminal plug; other site
1133852012807	ligand-binding site [chemical binding]; other site
1133852012808	ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594
1133852012809	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1133852012810	siderophore binding site; other site
1133852012811	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852012812	ABC-ATPase subunit  interface; other site
1133852012813	dimer interface [polypeptide binding]; other site
1133852012814	putative PBP binding regions; other site
1133852012815	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1133852012816	ABC-ATPase subunit  interface; other site
1133852012817	dimer interface [polypeptide binding]; other site
1133852012818	putative PBP binding regions; other site
1133852012819	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
1133852012820	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1133852012821	Walker A/P-loop; other site
1133852012822	ATP binding site [chemical binding]; other site
1133852012823	Q-loop/lid; other site
1133852012824	ABC transporter signature motif; other site
1133852012825	Walker B; other site
1133852012826	D-loop; other site
1133852012827	H-loop/switch region; other site
1133852012828	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1133852012829	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133852012830	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133852012831	putative active site [active]
1133852012832	putative NTP binding site [chemical binding]; other site
1133852012833	putative nucleic acid binding site [nucleotide binding]; other site
1133852012834	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133852012835	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852012836	Transposase; Region: HTH_Tnp_1; cl17663
1133852012837	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1133852012838	putative active site [active]
1133852012839	putative metal binding site [ion binding]; other site
1133852012840	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1133852012841	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1133852012842	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1133852012843	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1133852012844	putative acyl-acceptor binding pocket; other site
1133852012845	HTH-like domain; Region: HTH_21; pfam13276
1133852012846	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1133852012847	Integrase core domain; Region: rve; pfam00665
1133852012848	Integrase core domain; Region: rve_3; pfam13683
1133852012849	BCCT family transporter; Region: BCCT; cl00569
1133852012850	Predicted membrane protein [Function unknown]; Region: COG4325
1133852012851	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
1133852012852	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133852012853	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852012854	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852012855	Transposase; Region: HTH_Tnp_1; pfam01527
1133852012856	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852012857	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852012858	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133852012859	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852012860	zinc-finger binding domain of transposase IS66; Region: zf-IS66; pfam13005
1133852012861	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852012862	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852012863	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1133852012864	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1133852012865	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1133852012866	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1133852012867	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852012868	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1133852012869	substrate binding site [chemical binding]; other site
1133852012870	dimer interface [polypeptide binding]; other site
1133852012871	ATP binding site [chemical binding]; other site
1133852012872	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1133852012873	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852012874	putative substrate translocation pore; other site
1133852012875	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1133852012876	active site
1133852012877	catalytic residues [active]
1133852012878	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1133852012879	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1133852012880	active site
1133852012881	P-loop; other site
1133852012882	phosphorylation site [posttranslational modification]
1133852012883	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852012884	active site
1133852012885	phosphorylation site [posttranslational modification]
1133852012886	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1133852012887	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852012888	DNA binding site [nucleotide binding]
1133852012889	domain linker motif; other site
1133852012890	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1133852012891	putative dimerization interface [polypeptide binding]; other site
1133852012892	putative ligand binding site [chemical binding]; other site
1133852012893	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1133852012894	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1133852012895	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1133852012896	putative active site cavity [active]
1133852012897	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1133852012898	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133852012899	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852012900	active site turn [active]
1133852012901	phosphorylation site [posttranslational modification]
1133852012902	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1133852012903	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1133852012904	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1133852012905	putative active site [active]
1133852012906	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133852012907	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852012908	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852012909	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852012910	Fic family protein [Function unknown]; Region: COG3177
1133852012911	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
1133852012912	Fic/DOC family; Region: Fic; pfam02661
1133852012913	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852012914	salt bridge; other site
1133852012915	non-specific DNA binding site [nucleotide binding]; other site
1133852012916	sequence-specific DNA binding site [nucleotide binding]; other site
1133852012917	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852012918	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852012919	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852012920	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1133852012921	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1133852012922	HNH endonuclease; Region: HNH_2; pfam13391
1133852012923	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1133852012924	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1133852012925	Putative helicase; Region: TraI_2; pfam07514
1133852012926	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
1133852012927	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1133852012928	Phage integrase, N-terminal SAM-like domain; Region: Phage_int_SAM_4; cl17873
1133852012929	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1133852012930	active site
1133852012931	catalytic residues [active]
1133852012932	DNA binding site [nucleotide binding]
1133852012933	Int/Topo IB signature motif; other site
1133852012934	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1133852012935	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1133852012936	putative NAD(P) binding site [chemical binding]; other site
1133852012937	putative substrate binding site [chemical binding]; other site
1133852012938	catalytic Zn binding site [ion binding]; other site
1133852012939	structural Zn binding site [ion binding]; other site
1133852012940	dimer interface [polypeptide binding]; other site
1133852012941	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1133852012942	AAA domain; Region: AAA_33; pfam13671
1133852012943	ATP-binding site [chemical binding]; other site
1133852012944	Gluconate-6-phosphate binding site [chemical binding]; other site
1133852012945	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1133852012946	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1133852012947	putative NAD(P) binding site [chemical binding]; other site
1133852012948	catalytic Zn binding site [ion binding]; other site
1133852012949	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
1133852012950	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1133852012951	NADP binding site [chemical binding]; other site
1133852012952	homodimer interface [polypeptide binding]; other site
1133852012953	active site
1133852012954	gluconate transporter; Region: gntP; TIGR00791
1133852012955	GntP family permease; Region: GntP_permease; pfam02447
1133852012956	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1133852012957	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852012958	DNA binding site [nucleotide binding]
1133852012959	domain linker motif; other site
1133852012960	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1133852012961	putative dimerization interface [polypeptide binding]; other site
1133852012962	putative ligand binding site [chemical binding]; other site
1133852012963	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1133852012964	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852012965	Walker A motif; other site
1133852012966	ATP binding site [chemical binding]; other site
1133852012967	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1133852012968	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1133852012969	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1133852012970	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1133852012971	interface (dimer of trimers) [polypeptide binding]; other site
1133852012972	Substrate-binding/catalytic site; other site
1133852012973	Zn-binding sites [ion binding]; other site
1133852012974	DNA polymerase III subunit chi; Validated; Region: PRK05728
1133852012975	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1133852012976	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1133852012977	active site
1133852012978	HIGH motif; other site
1133852012979	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1133852012980	KMSKS motif; other site
1133852012981	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1133852012982	tRNA binding surface [nucleotide binding]; other site
1133852012983	anticodon binding site; other site
1133852012984	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1133852012985	Predicted membrane protein [Function unknown]; Region: COG4269
1133852012986	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133852012987	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852012988	Coenzyme A binding pocket [chemical binding]; other site
1133852012989	RNase E inhibitor protein; Provisional; Region: PRK11191
1133852012990	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1133852012991	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1133852012992	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1133852012993	SopA-like central domain; Region: SopA; pfam13981
1133852012994	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
1133852012995	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1133852012996	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852012997	oxidoreductase; Provisional; Region: PRK12742
1133852012998	classical (c) SDRs; Region: SDR_c; cd05233
1133852012999	NAD(P) binding site [chemical binding]; other site
1133852013000	active site
1133852013001	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1133852013002	homotrimer interaction site [polypeptide binding]; other site
1133852013003	putative active site [active]
1133852013004	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
1133852013005	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
1133852013006	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1133852013007	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1133852013008	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1133852013009	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1133852013010	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1133852013011	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1133852013012	homotrimer interaction site [polypeptide binding]; other site
1133852013013	putative active site [active]
1133852013014	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852013015	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852013016	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852013017	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1133852013018	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1133852013019	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1133852013020	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1133852013021	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852013022	motif II; other site
1133852013023	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1133852013024	trehalose repressor; Provisional; Region: treR; PRK09492
1133852013025	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852013026	DNA binding site [nucleotide binding]
1133852013027	domain linker motif; other site
1133852013028	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1133852013029	dimerization interface [polypeptide binding]; other site
1133852013030	ligand binding site [chemical binding]; other site
1133852013031	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1133852013032	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852013033	active site turn [active]
1133852013034	phosphorylation site [posttranslational modification]
1133852013035	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133852013036	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1133852013037	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1133852013038	Ca binding site [ion binding]; other site
1133852013039	active site
1133852013040	catalytic site [active]
1133852013041	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1133852013042	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1133852013043	ATP cone domain; Region: ATP-cone; pfam03477
1133852013044	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1133852013045	effector binding site; other site
1133852013046	active site
1133852013047	Zn binding site [ion binding]; other site
1133852013048	glycine loop; other site
1133852013049	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1133852013050	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852013051	FeS/SAM binding site; other site
1133852013052	cytochrome b562; Provisional; Region: PRK15058
1133852013053	peptidase PmbA; Provisional; Region: PRK11040
1133852013054	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3028
1133852013055	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1133852013056	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1133852013057	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1133852013058	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1133852013059	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1133852013060	AMP binding site [chemical binding]; other site
1133852013061	metal binding site [ion binding]; metal-binding site
1133852013062	active site
1133852013063	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852013064	TM-ABC transporter signature motif; other site
1133852013065	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852013066	TM-ABC transporter signature motif; other site
1133852013067	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1133852013068	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852013069	Walker A/P-loop; other site
1133852013070	ATP binding site [chemical binding]; other site
1133852013071	Q-loop/lid; other site
1133852013072	ABC transporter signature motif; other site
1133852013073	Walker B; other site
1133852013074	D-loop; other site
1133852013075	H-loop/switch region; other site
1133852013076	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852013077	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1133852013078	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1133852013079	putative ligand binding site [chemical binding]; other site
1133852013080	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1133852013081	dimer interface [polypeptide binding]; other site
1133852013082	substrate binding site [chemical binding]; other site
1133852013083	metal binding sites [ion binding]; metal-binding site
1133852013084	toxin ChpB; Provisional; Region: PRK09812
1133852013085	antitoxin ChpS; Provisional; Region: PRK11347
1133852013086	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1133852013087	putative active site pocket [active]
1133852013088	dimerization interface [polypeptide binding]; other site
1133852013089	putative catalytic residue [active]
1133852013090	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1133852013091	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1133852013092	Family of unknown function (DUF490); Region: DUF490; pfam04357
1133852013093	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1133852013094	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852013095	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1133852013096	Surface antigen; Region: Bac_surface_Ag; pfam01103
1133852013097	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1133852013098	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1133852013099	Domain of unknown function DUF21; Region: DUF21; pfam01595
1133852013100	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1133852013101	Transporter associated domain; Region: CorC_HlyC; smart01091
1133852013102	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1133852013103	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1133852013104	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1133852013105	active site
1133852013106	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1133852013107	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1133852013108	active site
1133852013109	metal binding site [ion binding]; metal-binding site
1133852013110	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1133852013111	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1133852013112	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1133852013113	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1133852013114	NADP binding site [chemical binding]; other site
1133852013115	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1133852013116	EamA-like transporter family; Region: EamA; pfam00892
1133852013117	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1133852013118	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1133852013119	Hemerythrin-like domain; Region: Hr-like; cd12108
1133852013120	Fe binding site [ion binding]; other site
1133852013121	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1133852013122	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852013123	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1133852013124	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1133852013125	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1133852013126	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1133852013127	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1133852013128	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1133852013129	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1133852013130	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1133852013131	Probable transposase; Region: OrfB_IS605; pfam01385
1133852013132	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1133852013133	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1133852013134	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
1133852013135	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1133852013136	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1133852013137	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1133852013138	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1133852013139	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1133852013140	dimer interface [polypeptide binding]; other site
1133852013141	ssDNA binding site [nucleotide binding]; other site
1133852013142	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133852013143	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1133852013144	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852013145	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
1133852013146	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133852013147	intersubunit interface [polypeptide binding]; other site
1133852013148	active site
1133852013149	Zn2+ binding site [ion binding]; other site
1133852013150	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1133852013151	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1133852013152	AP (apurinic/apyrimidinic) site pocket; other site
1133852013153	DNA interaction; other site
1133852013154	Metal-binding active site; metal-binding site
1133852013155	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1133852013156	active site
1133852013157	dimer interface [polypeptide binding]; other site
1133852013158	magnesium binding site [ion binding]; other site
1133852013159	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852013160	active site
1133852013161	phosphorylation site [posttranslational modification]
1133852013162	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1133852013163	active site
1133852013164	P-loop; other site
1133852013165	phosphorylation site [posttranslational modification]
1133852013166	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1133852013167	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1133852013168	transcriptional repressor UlaR; Provisional; Region: PRK13509
1133852013169	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852013170	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852013171	esterase; Provisional; Region: PRK10566
1133852013172	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1133852013173	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1133852013174	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1133852013175	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1133852013176	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1133852013177	FAD binding site [chemical binding]; other site
1133852013178	substrate binding site [chemical binding]; other site
1133852013179	catalytic residues [active]
1133852013180	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1133852013181	Predicted integral membrane protein [Function unknown]; Region: COG5463
1133852013182	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1133852013183	Predicted membrane protein [Function unknown]; Region: COG3766
1133852013184	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1133852013185	PspA/IM30 family; Region: PspA_IM30; pfam04012
1133852013186	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133852013187	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1133852013188	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1133852013189	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1133852013190	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1133852013191	exoribonuclease R; Provisional; Region: PRK11642
1133852013192	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
1133852013193	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1133852013194	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1133852013195	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
1133852013196	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1133852013197	RNA binding site [nucleotide binding]; other site
1133852013198	transcriptional repressor NsrR; Provisional; Region: PRK11014
1133852013199	Rrf2 family protein; Region: rrf2_super; TIGR00738
1133852013200	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1133852013201	GDP-binding site [chemical binding]; other site
1133852013202	ACT binding site; other site
1133852013203	IMP binding site; other site
1133852013204	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1133852013205	HflC protein; Region: hflC; TIGR01932
1133852013206	High frequency of lysogenization C (HflC) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflC; cd03405
1133852013207	FtsH protease regulator HflK; Provisional; Region: PRK10930
1133852013208	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1133852013209	High frequency of lysogenization K (HflK) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflK; cd03404
1133852013210	GTPase HflX; Provisional; Region: PRK11058
1133852013211	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1133852013212	HflX GTPase family; Region: HflX; cd01878
1133852013213	G1 box; other site
1133852013214	GTP/Mg2+ binding site [chemical binding]; other site
1133852013215	Switch I region; other site
1133852013216	G2 box; other site
1133852013217	G3 box; other site
1133852013218	Switch II region; other site
1133852013219	G4 box; other site
1133852013220	G5 box; other site
1133852013221	bacterial Hfq-like; Region: Hfq; cd01716
1133852013222	hexamer interface [polypeptide binding]; other site
1133852013223	Sm1 motif; other site
1133852013224	RNA binding site [nucleotide binding]; other site
1133852013225	Sm2 motif; other site
1133852013226	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1133852013227	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1133852013228	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852013229	ATP binding site [chemical binding]; other site
1133852013230	Mg2+ binding site [ion binding]; other site
1133852013231	G-X-G motif; other site
1133852013232	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1133852013233	ATP binding site [chemical binding]; other site
1133852013234	MutL C terminal dimerization domain; Region: MutL_C; pfam08676
1133852013235	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1133852013236	AMIN domain; Region: AMIN; pfam11741
1133852013237	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1133852013238	active site
1133852013239	metal binding site [ion binding]; metal-binding site
1133852013240	ADP-binding protein; Provisional; Region: PRK10646
1133852013241	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
1133852013242	putative carbohydrate kinase; Provisional; Region: PRK10565
1133852013243	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
1133852013244	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1133852013245	putative substrate binding site [chemical binding]; other site
1133852013246	putative ATP binding site [chemical binding]; other site
1133852013247	epoxyqueuosine reductase; Region: TIGR00276
1133852013248	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1133852013249	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1133852013250	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1133852013251	catalytic site [active]
1133852013252	putative active site [active]
1133852013253	putative substrate binding site [chemical binding]; other site
1133852013254	dimer interface [polypeptide binding]; other site
1133852013255	GTPase RsgA; Reviewed; Region: PRK12288
1133852013256	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1133852013257	RNA binding site [nucleotide binding]; other site
1133852013258	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1133852013259	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1133852013260	GTP/Mg2+ binding site [chemical binding]; other site
1133852013261	G4 box; other site
1133852013262	G5 box; other site
1133852013263	G1 box; other site
1133852013264	Switch I region; other site
1133852013265	G2 box; other site
1133852013266	G3 box; other site
1133852013267	Switch II region; other site
1133852013268	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1133852013269	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1133852013270	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
1133852013271	DNA-binding site [nucleotide binding]; DNA binding site
1133852013272	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1133852013273	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1133852013274	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1133852013275	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1133852013276	inner membrane transporter YjeM; Provisional; Region: PRK15238
1133852013277	poxB regulator PoxA; Provisional; Region: PRK09350
1133852013278	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1133852013279	motif 1; other site
1133852013280	dimer interface [polypeptide binding]; other site
1133852013281	active site
1133852013282	motif 2; other site
1133852013283	motif 3; other site
1133852013284	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1133852013285	L-aspartate oxidase; Provisional; Region: PRK06175
1133852013286	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1133852013287	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1133852013288	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1133852013289	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1133852013290	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1133852013291	D-subunit interface [polypeptide binding]; other site
1133852013292	Iron-sulfur protein interface; other site
1133852013293	proximal quinone binding site [chemical binding]; other site
1133852013294	distal quinone binding site [chemical binding]; other site
1133852013295	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1133852013296	Iron-sulfur protein interface; other site
1133852013297	proximal quinone binding site [chemical binding]; other site
1133852013298	C-subunit interface; other site
1133852013299	distal quinone binding site; other site
1133852013300	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1133852013301	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1133852013302	multidrug efflux system protein; Provisional; Region: PRK11431
1133852013303	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1133852013304	entericidin A; Provisional; Region: PRK09810
1133852013305	elongation factor P; Validated; Region: PRK00529
1133852013306	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1133852013307	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1133852013308	RNA binding site [nucleotide binding]; other site
1133852013309	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1133852013310	RNA binding site [nucleotide binding]; other site
1133852013311	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1133852013312	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852013313	FeS/SAM binding site; other site
1133852013314	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1133852013315	chaperonin GroEL; Reviewed; Region: groEL; PRK12850
1133852013316	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1133852013317	ring oligomerisation interface [polypeptide binding]; other site
1133852013318	ATP/Mg binding site [chemical binding]; other site
1133852013319	stacking interactions; other site
1133852013320	hinge regions; other site
1133852013321	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1133852013322	oligomerisation interface [polypeptide binding]; other site
1133852013323	mobile loop; other site
1133852013324	roof hairpin; other site
1133852013325	putative transporter; Provisional; Region: PRK11021
1133852013326	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852013327	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1133852013328	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1133852013329	Aspartase; Region: Aspartase; cd01357
1133852013330	active sites [active]
1133852013331	tetramer interface [polypeptide binding]; other site
1133852013332	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1133852013333	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1133852013334	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1133852013335	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1133852013336	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1133852013337	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1133852013338	DsbD alpha interface [polypeptide binding]; other site
1133852013339	catalytic residues [active]
1133852013340	putative transcriptional regulator; Provisional; Region: PRK11640
1133852013341	Bacterial regulatory proteins, tetR family; Region: TetR_N; cl19382
1133852013342	integrase; Provisional; Region: PRK09692
1133852013343	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1133852013344	active site
1133852013345	Int/Topo IB signature motif; other site
1133852013346	potential frameshift: common BLAST hit: gi|218697881|ref|YP_002405548.1| superfamily I DNA helicase
1133852013347	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852013348	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852013349	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852013350	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1133852013351	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852013352	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133852013353	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133852013354	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852013355	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852013356	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133852013357	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852013358	zinc-finger binding domain of transposase IS66; Region: zf-IS66; pfam13005
1133852013359	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852013360	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852013361	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852013362	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852013363	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133852013364	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133852013365	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852013366	Transposase; Region: HTH_Tnp_1; pfam01527
1133852013367	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852013368	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852013369	Transposase; Region: HTH_Tnp_1; cl17663
1133852013370	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852013371	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133852013372	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133852013373	putative active site [active]
1133852013374	putative NTP binding site [chemical binding]; other site
1133852013375	putative nucleic acid binding site [nucleotide binding]; other site
1133852013376	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133852013377	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1133852013378	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852013379	N-terminal plug; other site
1133852013380	ligand-binding site [chemical binding]; other site
1133852013381	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1133852013382	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852013383	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1133852013384	IucA / IucC family; Region: IucA_IucC; pfam04183
1133852013385	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1133852013386	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1133852013387	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
1133852013388	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1133852013389	IucA / IucC family; Region: IucA_IucC; pfam04183
1133852013390	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1133852013391	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852013392	putative substrate translocation pore; other site
1133852013393	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852013394	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1133852013395	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852013396	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852013397	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852013398	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852013399	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852013400	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1133852013401	Helix-turn-helix domain; Region: HTH_38; pfam13936
1133852013402	DNA-binding interface [nucleotide binding]; DNA binding site
1133852013403	Integrase core domain; Region: rve; pfam00665
1133852013404	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852013405	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1133852013406	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1133852013407	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852013408	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1133852013409	Transposase, Mutator family; Region: Transposase_mut; cl19537
1133852013410	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852013411	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133852013412	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133852013413	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852013414	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852013415	Integrase core domain; Region: rve; pfam00665
1133852013416	Integrase core domain; Region: rve_3; cl15866
1133852013417	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133852013418	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133852013419	putative active site [active]
1133852013420	putative NTP binding site [chemical binding]; other site
1133852013421	putative nucleic acid binding site [nucleotide binding]; other site
1133852013422	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133852013423	Transposase; Region: HTH_Tnp_1; cl17663
1133852013424	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852013425	Antirestriction protein; Region: Antirestrict; pfam03230
1133852013426	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1133852013427	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1133852013428	MPN+ (JAMM) motif; other site
1133852013429	Zinc-binding site [ion binding]; other site
1133852013430	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1133852013431	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1133852013432	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1133852013433	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1133852013434	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133852013435	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1133852013436	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852013437	DNA binding site [nucleotide binding]
1133852013438	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1133852013439	lysine decarboxylase CadA; Provisional; Region: PRK15400
1133852013440	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133852013441	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133852013442	homodimer interface [polypeptide binding]; other site
1133852013443	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852013444	catalytic residue [active]
1133852013445	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133852013446	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1133852013447	POT family; Region: PTR2; cl17359
1133852013448	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852013449	putative substrate translocation pore; other site
1133852013450	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1133852013451	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1133852013452	dimer interface [polypeptide binding]; other site
1133852013453	putative anticodon binding site; other site
1133852013454	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1133852013455	motif 1; other site
1133852013456	active site
1133852013457	motif 2; other site
1133852013458	motif 3; other site
1133852013459	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1133852013460	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1133852013461	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852013462	Coenzyme A binding pocket [chemical binding]; other site
1133852013463	Uncharacterized conserved protein [Function unknown]; Region: COG3592
1133852013464	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1133852013465	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
1133852013466	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852013467	putative active site [active]
1133852013468	heme pocket [chemical binding]; other site
1133852013469	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
1133852013470	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852013471	ATP binding site [chemical binding]; other site
1133852013472	Mg2+ binding site [ion binding]; other site
1133852013473	G-X-G motif; other site
1133852013474	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1133852013475	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852013476	active site
1133852013477	phosphorylation site [posttranslational modification]
1133852013478	intermolecular recognition site; other site
1133852013479	dimerization interface [polypeptide binding]; other site
1133852013480	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1133852013481	fumarate hydratase FumB; Provisional; Region: PRK15391
1133852013482	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1133852013483	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1133852013484	hypothetical protein; Provisional; Region: PRK09867
1133852013485	melibiose:sodium symporter; Provisional; Region: PRK10429
1133852013486	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1133852013487	alpha-galactosidase; Provisional; Region: PRK15076
1133852013488	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1133852013489	NAD binding site [chemical binding]; other site
1133852013490	sugar binding site [chemical binding]; other site
1133852013491	divalent metal binding site [ion binding]; other site
1133852013492	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133852013493	dimer interface [polypeptide binding]; other site
1133852013494	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1133852013495	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852013496	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852013497	arginine decarboxylase; Provisional; Region: PRK15029
1133852013498	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1133852013499	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1133852013500	homodimer interface [polypeptide binding]; other site
1133852013501	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852013502	catalytic residue [active]
1133852013503	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1133852013504	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852013505	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852013506	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852013507	arginine:agmatin antiporter; Provisional; Region: PRK10644
1133852013508	Spore germination protein; Region: Spore_permease; cl17796
1133852013509	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1133852013510	putative metal dependent hydrolase; Provisional; Region: PRK11598
1133852013511	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1133852013512	Sulfatase; Region: Sulfatase; pfam00884
1133852013513	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1133852013514	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852013515	active site
1133852013516	phosphorylation site [posttranslational modification]
1133852013517	intermolecular recognition site; other site
1133852013518	dimerization interface [polypeptide binding]; other site
1133852013519	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852013520	DNA binding site [nucleotide binding]
1133852013521	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1133852013522	HAMP domain; Region: HAMP; pfam00672
1133852013523	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852013524	dimer interface [polypeptide binding]; other site
1133852013525	phosphorylation site [posttranslational modification]
1133852013526	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852013527	ATP binding site [chemical binding]; other site
1133852013528	Mg2+ binding site [ion binding]; other site
1133852013529	G-X-G motif; other site
1133852013530	proline/glycine betaine transporter; Provisional; Region: PRK10642
1133852013531	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852013532	putative substrate translocation pore; other site
1133852013533	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1133852013534	YjcZ-like protein; Region: YjcZ; pfam13990
1133852013535	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1133852013536	G1 box; other site
1133852013537	GTP/Mg2+ binding site [chemical binding]; other site
1133852013538	G2 box; other site
1133852013539	Switch I region; other site
1133852013540	G3 box; other site
1133852013541	Switch II region; other site
1133852013542	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1133852013543	G2 box; other site
1133852013544	Switch I region; other site
1133852013545	G3 box; other site
1133852013546	Switch II region; other site
1133852013547	G4 box; other site
1133852013548	G5 box; other site
1133852013549	hypothetical protein; Provisional; Region: PRK10220
1133852013550	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1133852013551	PhnA protein; Region: PhnA; pfam03831
1133852013552	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1133852013553	dimer interface [polypeptide binding]; other site
1133852013554	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
1133852013555	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1133852013556	Walker A/P-loop; other site
1133852013557	ATP binding site [chemical binding]; other site
1133852013558	Q-loop/lid; other site
1133852013559	ABC transporter signature motif; other site
1133852013560	Walker B; other site
1133852013561	D-loop; other site
1133852013562	H-loop/switch region; other site
1133852013563	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1133852013564	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
1133852013565	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1133852013566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852013567	dimer interface [polypeptide binding]; other site
1133852013568	conserved gate region; other site
1133852013569	putative PBP binding loops; other site
1133852013570	ABC-ATPase subunit interface; other site
1133852013571	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1133852013572	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852013573	DNA-binding site [nucleotide binding]; DNA binding site
1133852013574	UTRA domain; Region: UTRA; pfam07702
1133852013575	Phosphonate metabolizm protein PhnG; Region: PhnG; pfam06754
1133852013576	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
1133852013577	Bacterial phosphonate metabolizm protein (PhnI); Region: PhnI; cl01456
1133852013578	Phosphonate metabolizm protein PhnJ; Region: PhnJ; pfam06007
1133852013579	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1133852013580	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1133852013581	Walker A/P-loop; other site
1133852013582	ATP binding site [chemical binding]; other site
1133852013583	Q-loop/lid; other site
1133852013584	ABC transporter signature motif; other site
1133852013585	Walker B; other site
1133852013586	D-loop; other site
1133852013587	H-loop/switch region; other site
1133852013588	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1133852013589	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1133852013590	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852013591	Walker A/P-loop; other site
1133852013592	ATP binding site [chemical binding]; other site
1133852013593	Q-loop/lid; other site
1133852013594	ABC transporter signature motif; other site
1133852013595	Walker B; other site
1133852013596	D-loop; other site
1133852013597	H-loop/switch region; other site
1133852013598	Metal-dependent hydrolase involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: COG3454
1133852013599	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1133852013600	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1133852013601	active site
1133852013602	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
1133852013603	Guanylate kinase; Region: Guanylate_kin; pfam00625
1133852013604	active site
1133852013605	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852013606	Coenzyme A binding pocket [chemical binding]; other site
1133852013607	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
1133852013608	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1133852013609	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1133852013610	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1133852013611	Alkyl sulfatase dimerization; Region: Alkyl_sulf_dimr; pfam14863
1133852013612	Alkyl sulfatase C-terminal; Region: Alkyl_sulf_C; pfam14864
1133852013613	multidrug resistance protein MdtN; Provisional; Region: PRK10476
1133852013614	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1133852013615	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1133852013616	HlyD family secretion protein; Region: HlyD_3; pfam13437
1133852013617	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
1133852013618	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1133852013619	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
1133852013620	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1133852013621	Outer membrane efflux protein; Region: OEP; pfam02321
1133852013622	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133852013623	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133852013624	molybdopterin cofactor binding site; other site
1133852013625	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1133852013626	molybdopterin cofactor binding site; other site
1133852013627	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1133852013628	Sel1-like repeats; Region: SEL1; smart00671
1133852013629	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1133852013630	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1133852013631	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1133852013632	binding surface
1133852013633	TPR motif; other site
1133852013634	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1133852013635	heme lyase subunit NrfE; Provisional; Region: PRK10369
1133852013636	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1133852013637	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1133852013638	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1133852013639	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852013640	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1133852013641	Cytochrome c7; Region: Cytochrome_C7; cl19206
1133852013642	Cytochrome c3; Region: Cytochrom_c3_2; pfam14537
1133852013643	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1133852013644	acetyl-CoA synthetase; Provisional; Region: PRK00174
1133852013645	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1133852013646	active site
1133852013647	CoA binding site [chemical binding]; other site
1133852013648	acyl-activating enzyme (AAE) consensus motif; other site
1133852013649	AMP binding site [chemical binding]; other site
1133852013650	acetate binding site [chemical binding]; other site
1133852013651	Predicted membrane protein [Function unknown]; Region: COG3162
1133852013652	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1133852013653	Na binding site [ion binding]; other site
1133852013654	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1133852013655	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1133852013656	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1133852013657	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1133852013658	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1133852013659	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1133852013660	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1133852013661	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133852013662	Sulfate transporter family; Region: Sulfate_transp; cl19250
1133852013663	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1133852013664	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1133852013665	DNA binding residues [nucleotide binding]
1133852013666	dimer interface [polypeptide binding]; other site
1133852013667	[2Fe-2S] cluster binding site [ion binding]; other site
1133852013668	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1133852013669	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852013670	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1133852013671	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1133852013672	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1133852013673	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1133852013674	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1133852013675	dimer interface [polypeptide binding]; other site
1133852013676	ssDNA binding site [nucleotide binding]; other site
1133852013677	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133852013678	putative single-stranded DNA-binding protein; Region: PHA01740
1133852013679	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1133852013680	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1133852013681	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1133852013682	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1133852013683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1133852013684	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
1133852013685	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852013686	active site
1133852013687	motif I; other site
1133852013688	motif II; other site
1133852013689	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1133852013690	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1133852013691	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852013692	homodimer interface [polypeptide binding]; other site
1133852013693	catalytic residue [active]
1133852013694	alanine racemase; Reviewed; Region: alr; PRK00053
1133852013695	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1133852013696	active site
1133852013697	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1133852013698	substrate binding site [chemical binding]; other site
1133852013699	catalytic residues [active]
1133852013700	dimer interface [polypeptide binding]; other site
1133852013701	replicative DNA helicase; Provisional; Region: PRK08006
1133852013702	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1133852013703	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1133852013704	Walker A motif; other site
1133852013705	ATP binding site [chemical binding]; other site
1133852013706	Walker B motif; other site
1133852013707	DNA binding loops [nucleotide binding]
1133852013708	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1133852013709	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1133852013710	NADP binding site [chemical binding]; other site
1133852013711	dimer interface [polypeptide binding]; other site
1133852013712	phage shock protein G; Reviewed; Region: pspG; PRK09459
1133852013713	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1133852013714	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
1133852013715	FMN binding site [chemical binding]; other site
1133852013716	active site
1133852013717	catalytic residues [active]
1133852013718	substrate binding site [chemical binding]; other site
1133852013719	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
1133852013720	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1133852013721	metal binding site 2 [ion binding]; metal-binding site
1133852013722	putative DNA binding helix; other site
1133852013723	metal binding site 1 [ion binding]; metal-binding site
1133852013724	dimer interface [polypeptide binding]; other site
1133852013725	structural Zn2+ binding site [ion binding]; other site
1133852013726	hypothetical protein; Provisional; Region: PRK10428
1133852013727	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1133852013728	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1133852013729	LexA repressor; Validated; Region: PRK00215
1133852013730	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1133852013731	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852013732	Catalytic site [active]
1133852013733	Integral membrane diacylglycerol kinase; Region: DAGK_IM; cd14264
1133852013734	putative active site [active]
1133852013735	trimer interface [polypeptide binding]; other site
1133852013736	putative active site [active]
1133852013737	Zn binding site [ion binding]; other site
1133852013738	Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; Region: PlsB; COG2937
1133852013739	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1133852013740	putative acyl-acceptor binding pocket; other site
1133852013741	4-Hydroxybenzoate polyprenyltransferase; Region: PT_UbiA_COQ2; cd13959
1133852013742	putative active site [active]
1133852013743	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1133852013744	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1133852013745	SopA-like central domain; Region: SopA; pfam13981
1133852013746	hypothetical protein; Validated; Region: PRK09718
1133852013747	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1133852013748	maltoporin; Provisional; Region: lamB; PRK09360
1133852013749	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1133852013750	trimer interface; other site
1133852013751	sugar binding site [chemical binding]; other site
1133852013752	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1133852013753	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1133852013754	Walker A/P-loop; other site
1133852013755	ATP binding site [chemical binding]; other site
1133852013756	Q-loop/lid; other site
1133852013757	ABC transporter signature motif; other site
1133852013758	Walker B; other site
1133852013759	D-loop; other site
1133852013760	H-loop/switch region; other site
1133852013761	TOBE domain; Region: TOBE_2; pfam08402
1133852013762	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1133852013763	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1133852013764	maltose transporter membrane protein; Provisional; Region: malF; PRK10999
1133852013765	Maltose transport system permease protein MalF P2 domain; Region: MalF_P2; pfam14785
1133852013766	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852013767	dimer interface [polypeptide binding]; other site
1133852013768	conserved gate region; other site
1133852013769	putative PBP binding loops; other site
1133852013770	ABC-ATPase subunit interface; other site
1133852013771	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1133852013772	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852013773	dimer interface [polypeptide binding]; other site
1133852013774	conserved gate region; other site
1133852013775	putative PBP binding loops; other site
1133852013776	ABC-ATPase subunit interface; other site
1133852013777	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1133852013778	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852013779	putative substrate translocation pore; other site
1133852013780	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1133852013781	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1133852013782	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1133852013783	Group 4 capsule polysaccharide formation lipoprotein gfcB; Region: Cap_synth_GfcB; pfam11102
1133852013784	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1133852013785	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1133852013786	active site
1133852013787	dimer interface [polypeptide binding]; other site
1133852013788	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1133852013789	dimer interface [polypeptide binding]; other site
1133852013790	active site
1133852013791	aspartate kinase III; Validated; Region: PRK09084
1133852013792	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
1133852013793	nucleotide binding site [chemical binding]; other site
1133852013794	putative catalytic residues [active]
1133852013795	aspartate binding site [chemical binding]; other site
1133852013796	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
1133852013797	lysine allosteric regulatory site; other site
1133852013798	dimer interface [polypeptide binding]; other site
1133852013799	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1133852013800	dimer interface [polypeptide binding]; other site
1133852013801	Zeta toxin; Region: Zeta_toxin; pfam06414
1133852013802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852013803	Walker A/P-loop; other site
1133852013804	ATP binding site [chemical binding]; other site
1133852013805	Q-loop/lid; other site
1133852013806	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1133852013807	Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_eoslipins_u2; cd13438
1133852013808	prohibitin homologues; Region: PHB; smart00244
1133852013809	hypothetical protein; Provisional; Region: PRK10515
1133852013810	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1133852013811	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1133852013812	RNA binding surface [nucleotide binding]; other site
1133852013813	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1133852013814	probable active site [active]
1133852013815	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1133852013816	active site pocket [active]
1133852013817	oxyanion hole [active]
1133852013818	catalytic triad [active]
1133852013819	active site nucleophile [active]
1133852013820	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1133852013821	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1133852013822	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1133852013823	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1133852013824	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1133852013825	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1133852013826	substrate binding pocket [chemical binding]; other site
1133852013827	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1133852013828	B12 binding site [chemical binding]; other site
1133852013829	cobalt ligand [ion binding]; other site
1133852013830	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1133852013831	transcriptional repressor IclR; Provisional; Region: PRK11569
1133852013832	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1133852013833	Bacterial transcriptional regulator; Region: IclR; pfam01614
1133852013834	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
1133852013835	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1133852013836	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1133852013837	tetramer interface [polypeptide binding]; other site
1133852013838	active site
1133852013839	Mg2+/Mn2+ binding site [ion binding]; other site
1133852013840	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1133852013841	active site
1133852013842	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1133852013843	proposed active site lysine [active]
1133852013844	conserved cys residue [active]
1133852013845	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1133852013846	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852013847	Coenzyme A binding pocket [chemical binding]; other site
1133852013848	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1133852013849	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1133852013850	purine monophosphate binding site [chemical binding]; other site
1133852013851	dimer interface [polypeptide binding]; other site
1133852013852	putative catalytic residues [active]
1133852013853	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1133852013854	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1133852013855	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1133852013856	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1133852013857	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1133852013858	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1133852013859	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852013860	active site
1133852013861	phosphorylation site [posttranslational modification]
1133852013862	intermolecular recognition site; other site
1133852013863	dimerization interface [polypeptide binding]; other site
1133852013864	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852013865	Walker A motif; other site
1133852013866	ATP binding site [chemical binding]; other site
1133852013867	Walker B motif; other site
1133852013868	arginine finger; other site
1133852013869	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133852013870	sensor protein ZraS; Provisional; Region: PRK10364
1133852013871	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852013872	dimer interface [polypeptide binding]; other site
1133852013873	phosphorylation site [posttranslational modification]
1133852013874	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852013875	ATP binding site [chemical binding]; other site
1133852013876	Mg2+ binding site [ion binding]; other site
1133852013877	G-X-G motif; other site
1133852013878	zinc resistance protein; Provisional; Region: zraP; PRK11546
1133852013879	dimer interface [polypeptide binding]; other site
1133852013880	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1133852013881	histone-like DNA-binding protein HU; Region: HU; cd13831
1133852013882	dimer interface [polypeptide binding]; other site
1133852013883	DNA binding site [nucleotide binding]
1133852013884	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1133852013885	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1133852013886	Active_site [active]
1133852013887	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1133852013888	substrate binding site [chemical binding]; other site
1133852013889	active site
1133852013890	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1133852013891	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1133852013892	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1133852013893	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1133852013894	putative NADH binding site [chemical binding]; other site
1133852013895	putative active site [active]
1133852013896	nudix motif; other site
1133852013897	putative metal binding site [ion binding]; other site
1133852013898	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1133852013899	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1133852013900	ThiC-associated domain; Region: ThiC-associated; pfam13667
1133852013901	ThiC family; Region: ThiC; pfam01964
1133852013902	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1133852013903	thiamine phosphate binding site [chemical binding]; other site
1133852013904	active site
1133852013905	pyrophosphate binding site [ion binding]; other site
1133852013906	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1133852013907	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1133852013908	ATP binding site [chemical binding]; other site
1133852013909	substrate interface [chemical binding]; other site
1133852013910	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1133852013911	thiS-thiF/thiG interaction site; other site
1133852013912	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1133852013913	ThiS interaction site; other site
1133852013914	putative active site [active]
1133852013915	tetramer interface [polypeptide binding]; other site
1133852013916	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1133852013917	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852013918	FeS/SAM binding site; other site
1133852013919	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1133852013920	stationary phase growth adaptation protein; Provisional; Region: PRK09717
1133852013921	Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609
1133852013922	beta and beta' interface [polypeptide binding]; other site
1133852013923	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1133852013924	beta' and sigma factor interface [polypeptide binding]; other site
1133852013925	Zn-binding [ion binding]; other site
1133852013926	active site region [active]
1133852013927	catalytic site [active]
1133852013928	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1133852013929	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1133852013930	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1133852013931	G-loop; other site
1133852013932	DNA binding site [nucleotide binding]
1133852013933	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1133852013934	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1133852013935	RPB12 interaction site [polypeptide binding]; other site
1133852013936	RPB1 interaction site [polypeptide binding]; other site
1133852013937	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
1133852013938	RPB10 interaction site [polypeptide binding]; other site
1133852013939	RPB11 interaction site [polypeptide binding]; other site
1133852013940	RPB3 interaction site [polypeptide binding]; other site
1133852013941	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1133852013942	core dimer interface [polypeptide binding]; other site
1133852013943	peripheral dimer interface [polypeptide binding]; other site
1133852013944	L10 interface [polypeptide binding]; other site
1133852013945	L11 interface [polypeptide binding]; other site
1133852013946	putative EF-Tu interaction site [polypeptide binding]; other site
1133852013947	putative EF-G interaction site [polypeptide binding]; other site
1133852013948	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1133852013949	23S rRNA interface [nucleotide binding]; other site
1133852013950	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1133852013951	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1133852013952	mRNA/rRNA interface [nucleotide binding]; other site
1133852013953	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1133852013954	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1133852013955	23S rRNA interface [nucleotide binding]; other site
1133852013956	L7/L12 interface [polypeptide binding]; other site
1133852013957	putative thiostrepton binding site; other site
1133852013958	L25 interface [polypeptide binding]; other site
1133852013959	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1133852013960	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1133852013961	putative homodimer interface [polypeptide binding]; other site
1133852013962	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1133852013963	heterodimer interface [polypeptide binding]; other site
1133852013964	homodimer interface [polypeptide binding]; other site
1133852013965	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1133852013966	elongation factor Tu; Reviewed; Region: PRK00049
1133852013967	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1133852013968	G1 box; other site
1133852013969	GEF interaction site [polypeptide binding]; other site
1133852013970	GTP/Mg2+ binding site [chemical binding]; other site
1133852013971	Switch I region; other site
1133852013972	G2 box; other site
1133852013973	G3 box; other site
1133852013974	Switch II region; other site
1133852013975	G4 box; other site
1133852013976	G5 box; other site
1133852013977	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1133852013978	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1133852013979	Antibiotic Binding Site [chemical binding]; other site
1133852013980	potential protein location (hypothetical protein O3K_23965 [Escherichia coli O104:H4 str. 2011C-3493]) that overlaps RNA (tRNA-T)
1133852013981	potential protein location (hypothetical protein O3K_23965 [Escherichia coli O104:H4 str. 2011C-3493]) that overlaps RNA (tRNA-Y)
1133852013982	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1133852013983	ATP-binding site [chemical binding]; other site
1133852013984	CoA-binding site [chemical binding]; other site
1133852013985	Mg2+-binding site [ion binding]; other site
1133852013986	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1133852013987	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1133852013988	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1133852013989	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1133852013990	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1133852013991	FAD binding domain; Region: FAD_binding_4; pfam01565
1133852013992	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1133852013993	glutamate racemase; Provisional; Region: PRK00865
1133852013994	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1133852013995	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1133852013996	N-terminal plug; other site
1133852013997	ligand-binding site [chemical binding]; other site
1133852013998	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1133852013999	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852014000	S-adenosylmethionine binding site [chemical binding]; other site
1133852014001	hypothetical protein; Provisional; Region: PRK11056
1133852014002	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1133852014003	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1133852014004	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1133852014005	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1133852014006	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1133852014007	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1133852014008	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1133852014009	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852014010	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1133852014011	dimerization interface [polypeptide binding]; other site
1133852014012	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852014013	D-galactonate transporter; Region: 2A0114; TIGR00893
1133852014014	putative substrate translocation pore; other site
1133852014015	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1133852014016	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1133852014017	putative active site pocket [active]
1133852014018	putative metal binding site [ion binding]; other site
1133852014019	argininosuccinate lyase; Provisional; Region: PRK04833
1133852014020	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1133852014021	active sites [active]
1133852014022	tetramer interface [polypeptide binding]; other site
1133852014023	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1133852014024	nucleotide binding site [chemical binding]; other site
1133852014025	N-acetyl-L-glutamate binding site [chemical binding]; other site
1133852014026	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
1133852014027	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
1133852014028	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
1133852014029	acetylornithine deacetylase (ArgE); Region: AcOrn-deacetyl; TIGR01892
1133852014030	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1133852014031	metal binding site [ion binding]; metal-binding site
1133852014032	putative dimer interface [polypeptide binding]; other site
1133852014033	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1133852014034	hypothetical protein; Provisional; Region: PRK10649
1133852014035	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1133852014036	Sulfatase; Region: Sulfatase; pfam00884
1133852014037	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852014038	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852014039	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852014040	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133852014041	active site
1133852014042	P-loop; other site
1133852014043	phosphorylation site [posttranslational modification]
1133852014044	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1133852014045	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852014046	FeS/SAM binding site; other site
1133852014047	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1133852014048	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1133852014049	dimer interface [polypeptide binding]; other site
1133852014050	active site
1133852014051	glycine loop; other site
1133852014052	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133852014053	active site
1133852014054	P-loop; other site
1133852014055	phosphorylation site [posttranslational modification]
1133852014056	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1133852014057	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1133852014058	dimerization domain swap beta strand [polypeptide binding]; other site
1133852014059	regulatory protein interface [polypeptide binding]; other site
1133852014060	active site
1133852014061	regulatory phosphorylation site [posttranslational modification]; other site
1133852014062	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
1133852014063	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1133852014064	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1133852014065	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1133852014066	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852014067	active site
1133852014068	phosphorylation site [posttranslational modification]
1133852014069	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1133852014070	active site
1133852014071	intersubunit interactions; other site
1133852014072	catalytic residue [active]
1133852014073	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1133852014074	dimer interface [polypeptide binding]; other site
1133852014075	active site
1133852014076	metal binding site [ion binding]; metal-binding site
1133852014077	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852014078	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1133852014079	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1133852014080	EamA-like transporter family; Region: EamA; pfam00892
1133852014081	EamA-like transporter family; Region: EamA; pfam00892
1133852014082	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1133852014083	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1133852014084	heme binding site [chemical binding]; other site
1133852014085	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1133852014086	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1133852014087	FAD binding site [chemical binding]; other site
1133852014088	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1133852014089	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1133852014090	putative catalytic residues [active]
1133852014091	putative nucleotide binding site [chemical binding]; other site
1133852014092	putative aspartate binding site [chemical binding]; other site
1133852014093	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1133852014094	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1133852014095	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1133852014096	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1133852014097	homodimer interface [polypeptide binding]; other site
1133852014098	substrate-cofactor binding pocket; other site
1133852014099	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852014100	catalytic residue [active]
1133852014101	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1133852014102	dimerization interface [polypeptide binding]; other site
1133852014103	DNA binding site [nucleotide binding]
1133852014104	corepressor binding sites; other site
1133852014105	potential frameshift: common BLAST hit: gi|254795943|ref|YP_003080780.1| peptidoglycan peptidase
1133852014106	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852014107	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852014108	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852014109	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133852014110	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1133852014111	PAAR motif; Region: PAAR_motif; cl15808
1133852014112	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852014113	RHS Repeat; Region: RHS_repeat; pfam05593
1133852014114	RHS Repeat; Region: RHS_repeat; pfam05593
1133852014115	RHS Repeat; Region: RHS_repeat; pfam05593
1133852014116	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1133852014117	RHS Repeat; Region: RHS_repeat; pfam05593
1133852014118	RHS Repeat; Region: RHS_repeat; pfam05593
1133852014119	RHS protein; Region: RHS; pfam03527
1133852014120	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1133852014121	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1133852014122	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1133852014123	primosome assembly protein PriA; Validated; Region: PRK05580
1133852014124	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852014125	ATP binding site [chemical binding]; other site
1133852014126	putative Mg++ binding site [ion binding]; other site
1133852014127	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1133852014128	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852014129	DNA binding site [nucleotide binding]
1133852014130	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1133852014131	domain linker motif; other site
1133852014132	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1133852014133	dimerization interface [polypeptide binding]; other site
1133852014134	ligand binding site [chemical binding]; other site
1133852014135	essential cell division protein FtsN; Provisional; Region: PRK10927
1133852014136	Sporulation related domain; Region: SPOR; pfam05036
1133852014137	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1133852014138	active site
1133852014139	HslU subunit interaction site [polypeptide binding]; other site
1133852014140	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1133852014141	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852014142	Walker A motif; other site
1133852014143	ATP binding site [chemical binding]; other site
1133852014144	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1133852014145	Walker B motif; other site
1133852014146	arginine finger; other site
1133852014147	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1133852014148	1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Region: PT_UbiA_UBIAD1; cd13962
1133852014149	putative active site [active]
1133852014150	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1133852014151	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1133852014152	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1133852014153	amphipathic channel; other site
1133852014154	Asn-Pro-Ala signature motifs; other site
1133852014155	glycerol kinase; Provisional; Region: glpK; PRK00047
1133852014156	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1133852014157	N- and C-terminal domain interface [polypeptide binding]; other site
1133852014158	active site
1133852014159	MgATP binding site [chemical binding]; other site
1133852014160	catalytic site [active]
1133852014161	metal binding site [ion binding]; metal-binding site
1133852014162	glycerol binding site [chemical binding]; other site
1133852014163	homotetramer interface [polypeptide binding]; other site
1133852014164	homodimer interface [polypeptide binding]; other site
1133852014165	FBP binding site [chemical binding]; other site
1133852014166	protein IIAGlc interface [polypeptide binding]; other site
1133852014167	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1133852014168	putative active site [active]
1133852014169	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1133852014170	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1133852014171	FAD binding pocket [chemical binding]; other site
1133852014172	FAD binding motif [chemical binding]; other site
1133852014173	phosphate binding motif [ion binding]; other site
1133852014174	beta-alpha-beta structure motif; other site
1133852014175	NAD binding pocket [chemical binding]; other site
1133852014176	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1133852014177	Ligand Binding Site [chemical binding]; other site
1133852014178	hypothetical protein; Provisional; Region: PRK09981
1133852014179	Predicted membrane protein [Function unknown]; Region: COG3152
1133852014180	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1133852014181	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1133852014182	substrate binding site [chemical binding]; other site
1133852014183	dimer interface [polypeptide binding]; other site
1133852014184	catalytic triad [active]
1133852014185	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1133852014186	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852014187	substrate binding pocket [chemical binding]; other site
1133852014188	membrane-bound complex binding site; other site
1133852014189	hinge residues; other site
1133852014190	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1133852014191	active site
1133852014192	ADP/pyrophosphate binding site [chemical binding]; other site
1133852014193	dimerization interface [polypeptide binding]; other site
1133852014194	allosteric effector site; other site
1133852014195	fructose-1,6-bisphosphate binding site; other site
1133852014196	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1133852014197	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1133852014198	dimer interface [polypeptide binding]; other site
1133852014199	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1133852014200	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852014201	active site
1133852014202	intermolecular recognition site; other site
1133852014203	dimerization interface [polypeptide binding]; other site
1133852014204	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1133852014205	DNA binding site [nucleotide binding]
1133852014206	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1133852014207	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1133852014208	dimerization interface [polypeptide binding]; other site
1133852014209	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852014210	dimer interface [polypeptide binding]; other site
1133852014211	phosphorylation site [posttranslational modification]
1133852014212	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852014213	ATP binding site [chemical binding]; other site
1133852014214	Mg2+ binding site [ion binding]; other site
1133852014215	G-X-G motif; other site
1133852014216	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1133852014217	MOSC domain; Region: MOSC; pfam03473
1133852014218	3-alpha domain; Region: 3-alpha; pfam03475
1133852014219	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
1133852014220	superoxide dismutase; Provisional; Region: PRK10925
1133852014221	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1133852014222	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1133852014223	Sugar transport protein; Region: Sugar_transport; cl19288
1133852014224	transcriptional activator RhaR; Provisional; Region: PRK13500
1133852014225	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133852014226	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852014227	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852014228	transcriptional activator RhaS; Provisional; Region: PRK13503
1133852014229	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1133852014230	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852014231	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852014232	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1133852014233	N- and C-terminal domain interface [polypeptide binding]; other site
1133852014234	active site
1133852014235	putative catalytic site [active]
1133852014236	metal binding site [ion binding]; metal-binding site
1133852014237	ATP binding site [chemical binding]; other site
1133852014238	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1133852014239	carbohydrate binding site [chemical binding]; other site
1133852014240	L-rhamnose isomerase; Provisional; Region: PRK01076
1133852014241	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1133852014242	intersubunit interface [polypeptide binding]; other site
1133852014243	active site
1133852014244	Zn2+ binding site [ion binding]; other site
1133852014245	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1133852014246	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852014247	active site
1133852014248	phosphorylation site [posttranslational modification]
1133852014249	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1133852014250	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1133852014251	active site
1133852014252	P-loop; other site
1133852014253	phosphorylation site [posttranslational modification]
1133852014254	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1133852014255	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1133852014256	oligomer interface [polypeptide binding]; other site
1133852014257	active site
1133852014258	metal binding site [ion binding]; metal-binding site
1133852014259	putative frv operon regulatory protein; Provisional; Region: PRK09863
1133852014260	HTH domain; Region: HTH_11; pfam08279
1133852014261	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1133852014262	active site
1133852014263	phosphorylation site [posttranslational modification]
1133852014264	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1133852014265	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1133852014266	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
1133852014267	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133852014268	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1133852014269	molybdopterin cofactor binding site; other site
1133852014270	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1133852014271	molybdopterin cofactor binding site; other site
1133852014272	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1133852014273	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1133852014274	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1133852014275	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1133852014276	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1133852014277	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1133852014278	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1133852014279	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852014280	non-specific DNA binding site [nucleotide binding]; other site
1133852014281	salt bridge; other site
1133852014282	sequence-specific DNA binding site [nucleotide binding]; other site
1133852014283	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
1133852014284	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1133852014285	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852014286	Coenzyme A binding pocket [chemical binding]; other site
1133852014287	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1133852014288	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1133852014289	putative active site [active]
1133852014290	dimerization interface [polypeptide binding]; other site
1133852014291	putative tRNAtyr binding site [nucleotide binding]; other site
1133852014292	hypothetical protein; Reviewed; Region: PRK01637
1133852014293	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1133852014294	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1133852014295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852014296	motif II; other site
1133852014297	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
1133852014298	active site
1133852014299	catalytic residues [active]
1133852014300	shikimate transporter; Provisional; Region: PRK09952
1133852014301	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852014302	putative substrate translocation pore; other site
1133852014303	benzoate transport; Region: 2A0115; TIGR00895
1133852014304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852014305	putative substrate translocation pore; other site
1133852014306	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1133852014307	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1133852014308	NAD(P) binding site [chemical binding]; other site
1133852014309	Class I aldolases; Region: Aldolase_Class_I; cl17187
1133852014310	catalytic residue [active]
1133852014311	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1133852014312	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
1133852014313	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
1133852014314	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1133852014315	substrate binding site [chemical binding]; other site
1133852014316	ATP binding site [chemical binding]; other site
1133852014317	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1133852014318	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1133852014319	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1133852014320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852014321	putative substrate translocation pore; other site
1133852014322	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1133852014323	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1133852014324	transcriptional regulator protein; Region: phnR; TIGR03337
1133852014325	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852014326	DNA-binding site [nucleotide binding]; DNA binding site
1133852014327	UTRA domain; Region: UTRA; pfam07702
1133852014328	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1133852014329	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1133852014330	G1 box; other site
1133852014331	putative GEF interaction site [polypeptide binding]; other site
1133852014332	GTP/Mg2+ binding site [chemical binding]; other site
1133852014333	Switch I region; other site
1133852014334	G2 box; other site
1133852014335	G3 box; other site
1133852014336	Switch II region; other site
1133852014337	G4 box; other site
1133852014338	G5 box; other site
1133852014339	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1133852014340	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1133852014341	glutamine synthetase; Provisional; Region: glnA; PRK09469
1133852014342	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1133852014343	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1133852014344	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1133852014345	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1133852014346	putative active site [active]
1133852014347	heme pocket [chemical binding]; other site
1133852014348	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1133852014349	dimer interface [polypeptide binding]; other site
1133852014350	phosphorylation site [posttranslational modification]
1133852014351	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1133852014352	ATP binding site [chemical binding]; other site
1133852014353	Mg2+ binding site [ion binding]; other site
1133852014354	G-X-G motif; other site
1133852014355	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1133852014356	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1133852014357	active site
1133852014358	phosphorylation site [posttranslational modification]
1133852014359	intermolecular recognition site; other site
1133852014360	dimerization interface [polypeptide binding]; other site
1133852014361	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852014362	Walker A motif; other site
1133852014363	ATP binding site [chemical binding]; other site
1133852014364	Walker B motif; other site
1133852014365	arginine finger; other site
1133852014366	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1133852014367	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1133852014368	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852014369	FeS/SAM binding site; other site
1133852014370	HemN C-terminal domain; Region: HemN_C; pfam06969
1133852014371	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1133852014372	Predicted GTPase [General function prediction only]; Region: COG0218
1133852014373	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1133852014374	G1 box; other site
1133852014375	GTP/Mg2+ binding site [chemical binding]; other site
1133852014376	Switch I region; other site
1133852014377	G2 box; other site
1133852014378	G3 box; other site
1133852014379	Switch II region; other site
1133852014380	G4 box; other site
1133852014381	G5 box; other site
1133852014382	DNA polymerase I; Provisional; Region: PRK05755
1133852014383	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1133852014384	active site
1133852014385	metal binding site 1 [ion binding]; metal-binding site
1133852014386	putative 5' ssDNA interaction site; other site
1133852014387	metal binding site 3; metal-binding site
1133852014388	metal binding site 2 [ion binding]; metal-binding site
1133852014389	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1133852014390	putative DNA binding site [nucleotide binding]; other site
1133852014391	putative metal binding site [ion binding]; other site
1133852014392	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1133852014393	active site
1133852014394	catalytic site [active]
1133852014395	substrate binding site [chemical binding]; other site
1133852014396	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1133852014397	active site
1133852014398	DNA binding site [nucleotide binding]
1133852014399	catalytic site [active]
1133852014400	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1133852014401	putative acyl-acceptor binding pocket; other site
1133852014402	hypothetical protein; Provisional; Region: PRK11367
1133852014403	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1133852014404	catalytic residues [active]
1133852014405	hinge region; other site
1133852014406	alpha helical domain; other site
1133852014407	serine/threonine protein kinase; Provisional; Region: PRK11768
1133852014408	Phosphotransferase enzyme family; Region: APH; pfam01636
1133852014409	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1133852014410	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1133852014411	GTP binding site; other site
1133852014412	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1133852014413	Walker A motif; other site
1133852014414	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1133852014415	potassium transporter; Provisional; Region: PRK10750
1133852014416	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1133852014417	hypothetical protein; Provisional; Region: PRK11568
1133852014418	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1133852014419	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1133852014420	proline dipeptidase; Provisional; Region: PRK13607
1133852014421	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1133852014422	active site
1133852014423	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1133852014424	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1133852014425	substrate binding site [chemical binding]; other site
1133852014426	oxyanion hole (OAH) forming residues; other site
1133852014427	trimer interface [polypeptide binding]; other site
1133852014428	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1133852014429	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133852014430	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1133852014431	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1133852014432	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1133852014433	dimer interface [polypeptide binding]; other site
1133852014434	active site
1133852014435	FMN reductase; Validated; Region: fre; PRK08051
1133852014436	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1133852014437	FAD binding pocket [chemical binding]; other site
1133852014438	FAD binding motif [chemical binding]; other site
1133852014439	phosphate binding motif [ion binding]; other site
1133852014440	beta-alpha-beta structure motif; other site
1133852014441	NAD binding pocket [chemical binding]; other site
1133852014442	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1133852014443	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1133852014444	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1133852014445	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1133852014446	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1133852014447	active site
1133852014448	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1133852014449	sec-independent translocase; Provisional; Region: PRK01770
1133852014450	sec-independent translocase; Provisional; Region: tatB; PRK00404
1133852014451	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1133852014452	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1133852014453	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1133852014454	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1133852014455	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1133852014456	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852014457	S-adenosylmethionine binding site [chemical binding]; other site
1133852014458	DNA recombination protein RmuC; Provisional; Region: PRK10361
1133852014459	RmuC family; Region: RmuC; pfam02646
1133852014460	uridine phosphorylase; Provisional; Region: PRK11178
1133852014461	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1133852014462	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1133852014463	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1133852014464	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1133852014465	THF binding site; other site
1133852014466	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1133852014467	substrate binding site [chemical binding]; other site
1133852014468	THF binding site; other site
1133852014469	zinc-binding site [ion binding]; other site
1133852014470	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1133852014471	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852014472	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1133852014473	putative dimerization interface [polypeptide binding]; other site
1133852014474	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1133852014475	EamA-like transporter family; Region: EamA; pfam00892
1133852014476	putative hydrolase; Provisional; Region: PRK10976
1133852014477	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852014478	active site
1133852014479	motif I; other site
1133852014480	motif II; other site
1133852014481	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1133852014482	lysophospholipase L2; Provisional; Region: PRK10749
1133852014483	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1133852014484	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1133852014485	threonine efflux system; Provisional; Region: PRK10229
1133852014486	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1133852014487	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1133852014488	ATP binding site [chemical binding]; other site
1133852014489	putative Mg++ binding site [ion binding]; other site
1133852014490	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852014491	nucleotide binding region [chemical binding]; other site
1133852014492	ATP-binding site [chemical binding]; other site
1133852014493	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1133852014494	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1133852014495	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1133852014496	dimerization interface [polypeptide binding]; other site
1133852014497	substrate binding site [chemical binding]; other site
1133852014498	active site
1133852014499	calcium binding site [ion binding]; other site
1133852014500	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1133852014501	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
1133852014502	CoenzymeA binding site [chemical binding]; other site
1133852014503	subunit interaction site [polypeptide binding]; other site
1133852014504	PHB binding site; other site
1133852014505	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1133852014506	Multidrug resistance efflux transporter; Region: EmrE; cl19304
1133852014507	magnesium/nickel/cobalt transporter CorA; Provisional; Region: PRK11085
1133852014508	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
1133852014509	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
1133852014510	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1133852014511	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1133852014512	Cl binding site [ion binding]; other site
1133852014513	oligomer interface [polypeptide binding]; other site
1133852014514	Predicted periplasmic protein [Function unknown]; Region: COG3698
1133852014515	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1133852014516	Part of AAA domain; Region: AAA_19; pfam13245
1133852014517	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1133852014518	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1133852014519	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1133852014520	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852014521	motif II; other site
1133852014522	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1133852014523	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1133852014524	active site
1133852014525	Int/Topo IB signature motif; other site
1133852014526	hypothetical protein; Provisional; Region: PRK10963
1133852014527	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1133852014528	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1133852014529	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1133852014530	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1133852014531	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
1133852014532	DKNYY family; Region: DKNYY; pfam13644
1133852014533	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1133852014534	putative iron binding site [ion binding]; other site
1133852014535	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1133852014536	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1133852014537	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1133852014538	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1133852014539	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1133852014540	domain interfaces; other site
1133852014541	active site
1133852014542	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1133852014543	active site
1133852014544	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1133852014545	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1133852014546	HemY protein N-terminus; Region: HemY_N; pfam07219
1133852014547	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1133852014548	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1133852014549	FeS/SAM binding site; other site
1133852014550	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1133852014551	putative transport protein YifK; Provisional; Region: PRK10746
1133852014552	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1133852014553	putative common antigen polymerase; Provisional; Region: PRK02975
1133852014554	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1133852014555	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1133852014556	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1133852014557	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1133852014558	inhibitor-cofactor binding pocket; inhibition site
1133852014559	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852014560	catalytic residue [active]
1133852014561	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1133852014562	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1133852014563	Coenzyme A binding pocket [chemical binding]; other site
1133852014564	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1133852014565	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1133852014566	substrate binding site; other site
1133852014567	tetramer interface; other site
1133852014568	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1133852014569	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1133852014570	NAD binding site [chemical binding]; other site
1133852014571	substrate binding site [chemical binding]; other site
1133852014572	homodimer interface [polypeptide binding]; other site
1133852014573	active site
1133852014574	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1133852014575	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721
1133852014576	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1133852014577	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1133852014578	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1133852014579	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1133852014580	active site
1133852014581	homodimer interface [polypeptide binding]; other site
1133852014582	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1133852014583	Chain length determinant protein; Region: Wzz; pfam02706
1133852014584	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1133852014585	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
1133852014586	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1133852014587	Mg++ binding site [ion binding]; other site
1133852014588	putative catalytic motif [active]
1133852014589	substrate binding site [chemical binding]; other site
1133852014590	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1133852014591	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1133852014592	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1133852014593	RNA binding site [nucleotide binding]; other site
1133852014594	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1133852014595	multimer interface [polypeptide binding]; other site
1133852014596	Walker A motif; other site
1133852014597	ATP binding site [chemical binding]; other site
1133852014598	Walker B motif; other site
1133852014599	putative rho operon leader peptide; Provisional; Region: PRK09979
1133852014600	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1133852014601	catalytic residues [active]
1133852014602	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1133852014603	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1133852014604	ATP binding site [chemical binding]; other site
1133852014605	Mg++ binding site [ion binding]; other site
1133852014606	motif III; other site
1133852014607	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1133852014608	nucleotide binding region [chemical binding]; other site
1133852014609	ATP-binding site [chemical binding]; other site
1133852014610	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1133852014611	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1133852014612	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1133852014613	Part of AAA domain; Region: AAA_19; pfam13245
1133852014614	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1133852014615	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
1133852014616	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1133852014617	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1133852014618	ketol-acid reductoisomerase; Validated; Region: PRK05225
1133852014619	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1133852014620	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1133852014621	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852014622	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1133852014623	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1133852014624	putative dimerization interface [polypeptide binding]; other site
1133852014625	threonine dehydratase; Reviewed; Region: PRK09224
1133852014626	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1133852014627	tetramer interface [polypeptide binding]; other site
1133852014628	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1133852014629	catalytic residue [active]
1133852014630	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1133852014631	putative Ile/Val binding site [chemical binding]; other site
1133852014632	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1133852014633	putative Ile/Val binding site [chemical binding]; other site
1133852014634	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1133852014635	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1133852014636	homodimer interface [polypeptide binding]; other site
1133852014637	substrate-cofactor binding pocket; other site
1133852014638	catalytic residue [active]
1133852014639	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1133852014640	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1133852014641	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1133852014642	PYR/PP interface [polypeptide binding]; other site
1133852014643	dimer interface [polypeptide binding]; other site
1133852014644	TPP binding site [chemical binding]; other site
1133852014645	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1133852014646	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1133852014647	TPP-binding site [chemical binding]; other site
1133852014648	dimer interface [polypeptide binding]; other site
1133852014649	putative ATP-dependent protease; Provisional; Region: PRK09862
1133852014650	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1133852014651	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852014652	Walker A motif; other site
1133852014653	ATP binding site [chemical binding]; other site
1133852014654	Walker B motif; other site
1133852014655	arginine finger; other site
1133852014656	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1133852014657	hypothetical protein; Provisional; Region: PRK11027
1133852014658	transcriptional regulator HdfR; Provisional; Region: PRK03601
1133852014659	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852014660	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1133852014661	dimerization interface [polypeptide binding]; other site
1133852014662	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1133852014663	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1133852014664	DNA-binding site [nucleotide binding]; DNA binding site
1133852014665	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1133852014666	putative transporter; Provisional; Region: PRK10504
1133852014667	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852014668	putative substrate translocation pore; other site
1133852014669	transcriptional repressor RbsR; Provisional; Region: PRK10423
1133852014670	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1133852014671	DNA binding site [nucleotide binding]
1133852014672	domain linker motif; other site
1133852014673	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1133852014674	dimerization interface [polypeptide binding]; other site
1133852014675	ligand binding site [chemical binding]; other site
1133852014676	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1133852014677	substrate binding site [chemical binding]; other site
1133852014678	dimer interface [polypeptide binding]; other site
1133852014679	ATP binding site [chemical binding]; other site
1133852014680	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1133852014681	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1133852014682	ligand binding site [chemical binding]; other site
1133852014683	dimerization interface [polypeptide binding]; other site
1133852014684	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1133852014685	TM-ABC transporter signature motif; other site
1133852014686	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1133852014687	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1133852014688	Walker A/P-loop; other site
1133852014689	ATP binding site [chemical binding]; other site
1133852014690	Q-loop/lid; other site
1133852014691	ABC transporter signature motif; other site
1133852014692	Walker B; other site
1133852014693	D-loop; other site
1133852014694	H-loop/switch region; other site
1133852014695	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1133852014696	D-ribose pyranase; Provisional; Region: PRK11797
1133852014697	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1133852014698	regulatory ATPase RavA; Provisional; Region: PRK13531
1133852014699	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1133852014700	Walker A motif; other site
1133852014701	ATP binding site [chemical binding]; other site
1133852014702	Walker B motif; other site
1133852014703	arginine finger; other site
1133852014704	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1133852014705	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2425
1133852014706	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1133852014707	metal ion-dependent adhesion site (MIDAS); other site
1133852014708	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1133852014709	dimer interface [polypeptide binding]; other site
1133852014710	active site
1133852014711	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1133852014712	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1133852014713	putative DNA binding site [nucleotide binding]; other site
1133852014714	putative Zn2+ binding site [ion binding]; other site
1133852014715	AsnC family; Region: AsnC_trans_reg; pfam01037
1133852014716	FMN-binding protein MioC; Provisional; Region: PRK09004
1133852014717	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1133852014718	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1133852014719	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1133852014720	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1133852014721	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1133852014722	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1133852014723	S-adenosylmethionine binding site [chemical binding]; other site
1133852014724	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1133852014725	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1133852014726	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1133852014727	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1133852014728	F0F1 ATP synthase subunit B; Provisional; Region: PRK14471; cl17192
1133852014729	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1133852014730	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1133852014731	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1133852014732	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1133852014733	beta subunit interaction interface [polypeptide binding]; other site
1133852014734	Walker A motif; other site
1133852014735	ATP binding site [chemical binding]; other site
1133852014736	Walker B motif; other site
1133852014737	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1133852014738	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1133852014739	core domain interface [polypeptide binding]; other site
1133852014740	delta subunit interface [polypeptide binding]; other site
1133852014741	epsilon subunit interface [polypeptide binding]; other site
1133852014742	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1133852014743	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1133852014744	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1133852014745	alpha subunit interaction interface [polypeptide binding]; other site
1133852014746	Walker A motif; other site
1133852014747	ATP binding site [chemical binding]; other site
1133852014748	Walker B motif; other site
1133852014749	inhibitor binding site; inhibition site
1133852014750	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1133852014751	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1133852014752	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1133852014753	gamma subunit interface [polypeptide binding]; other site
1133852014754	epsilon subunit interface [polypeptide binding]; other site
1133852014755	LBP interface [polypeptide binding]; other site
1133852014756	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1133852014757	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1133852014758	Substrate binding site; other site
1133852014759	Mg++ binding site; other site
1133852014760	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1133852014761	active site
1133852014762	substrate binding site [chemical binding]; other site
1133852014763	CoA binding site [chemical binding]; other site
1133852014764	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1133852014765	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1133852014766	glutaminase active site [active]
1133852014767	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1133852014768	dimer interface [polypeptide binding]; other site
1133852014769	active site
1133852014770	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1133852014771	dimer interface [polypeptide binding]; other site
1133852014772	active site
1133852014773	fimbrial protein; Provisional; Region: lpfA; PRK15289
1133852014774	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
1133852014775	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852014776	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852014777	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1133852014778	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852014779	Outer membrane usher protein; Region: Usher; pfam00577
1133852014780	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852014781	Fimbrial protein; Region: Fimbrial; cl01416
1133852014782	phosphate ABC transporter periplasmic substrate-binding protein PstS; Provisional; Region: PRK10918
1133852014783	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1133852014784	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1133852014785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852014786	dimer interface [polypeptide binding]; other site
1133852014787	conserved gate region; other site
1133852014788	putative PBP binding loops; other site
1133852014789	ABC-ATPase subunit interface; other site
1133852014790	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1133852014791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1133852014792	dimer interface [polypeptide binding]; other site
1133852014793	conserved gate region; other site
1133852014794	putative PBP binding loops; other site
1133852014795	ABC-ATPase subunit interface; other site
1133852014796	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1133852014797	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1133852014798	Walker A/P-loop; other site
1133852014799	ATP binding site [chemical binding]; other site
1133852014800	Q-loop/lid; other site
1133852014801	ABC transporter signature motif; other site
1133852014802	Walker B; other site
1133852014803	D-loop; other site
1133852014804	H-loop/switch region; other site
1133852014805	transcriptional regulator PhoU; Provisional; Region: PRK11115
1133852014806	PhoU domain; Region: PhoU; pfam01895
1133852014807	PhoU domain; Region: PhoU; pfam01895
1133852014808	potential frameshift: common BLAST hit: gi|260870453|ref|YP_003236855.1| transcriptional antiterminator of the bgl operon
1133852014809	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1133852014810	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1133852014811	active site turn [active]
1133852014812	phosphorylation site [posttranslational modification]
1133852014813	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1133852014814	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1133852014815	HPr interaction site; other site
1133852014816	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1133852014817	active site
1133852014818	phosphorylation site [posttranslational modification]
1133852014819	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1133852014820	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
1133852014821	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1133852014822	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1133852014823	maltoporin; Provisional; Region: lamB; PRK09360
1133852014824	trimer interface; other site
1133852014825	sugar binding site [chemical binding]; other site
1133852014826	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1133852014827	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1133852014828	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
1133852014829	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1133852014830	active site
1133852014831	trimer interface [polypeptide binding]; other site
1133852014832	allosteric site; other site
1133852014833	active site lid [active]
1133852014834	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
1133852014835	putative inner membrane protein; Provisional; Region: PRK09823
1133852014836	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1133852014837	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1133852014838	active site
1133852014839	motif I; other site
1133852014840	motif II; other site
1133852014841	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1133852014842	Predicted flavoprotein [General function prediction only]; Region: COG0431
1133852014843	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1133852014844	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1133852014845	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1133852014846	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1133852014847	substrate binding pocket [chemical binding]; other site
1133852014848	dimerization interface [polypeptide binding]; other site
1133852014849	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1133852014850	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1133852014851	putative substrate translocation pore; other site
1133852014852	tryptophan permease TnaB; Provisional; Region: PRK09664
1133852014853	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1133852014854	Tryptophanase [Amino acid transport and metabolism]; Region: TnaA; COG3033
1133852014855	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
1133852014856	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1133852014857	catalytic residue [active]
1133852014858	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
1133852014859	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1133852014860	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1133852014861	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1133852014862	G1 box; other site
1133852014863	GTP/Mg2+ binding site [chemical binding]; other site
1133852014864	Switch I region; other site
1133852014865	G2 box; other site
1133852014866	Switch II region; other site
1133852014867	G3 box; other site
1133852014868	G4 box; other site
1133852014869	G5 box; other site
1133852014870	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1133852014871	membrane protein insertase; Provisional; Region: PRK01318
1133852014872	YidC periplasmic domain; Region: YidC_periplas; pfam14849
1133852014873	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1133852014874	hypothetical protein; Validated; Region: PRK00041
1133852014875	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1133852014876	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1133852014877	AAA-like domain; Region: AAA_10; pfam12846
1133852014878	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
1133852014879	Protein of unknown function (DUF3625); Region: DUF3625; pfam12293
1133852014880	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
1133852014881	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1133852014882	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1133852014883	active site
1133852014884	metal binding site [ion binding]; metal-binding site
1133852014885	interdomain interaction site; other site
1133852014886	Relaxase/Mobilisation nuclease domain; Region: Relaxase; cl19391
1133852014887	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
1133852014888	PLD-like domain; Region: PLDc_2; pfam13091
1133852014889	putative active site [active]
1133852014890	catalytic site [active]
1133852014891	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1133852014892	Walker A motif; other site
1133852014893	ATP binding site [chemical binding]; other site
1133852014894	Walker B motif; other site
1133852014895	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1133852014896	catalytic core [active]
1133852014897	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1133852014898	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1133852014899	Rci recombinase, C-terminal catalytic domain.  Rci enzymes are found in IncI1 incompatibility group plasmids such as R64.  These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796
1133852014900	catalytic residues [active]
1133852014901	Int/Topo IB signature motif; other site
1133852014902	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1133852014903	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1133852014904	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1133852014905	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852014906	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852014907	catalytic residue [active]
1133852014908	PilS N terminal; Region: PilS; pfam08805
1133852014909	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133852014910	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1133852014911	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1133852014912	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1133852014913	Walker A motif; other site
1133852014914	ATP binding site [chemical binding]; other site
1133852014915	Walker B motif; other site
1133852014916	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
1133852014917	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
1133852014918	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
1133852014919	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
1133852014920	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1133852014921	PilM; Region: PilM; pfam07419
1133852014922	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
1133852014923	Plasmid conjugative transfer protein PilI; Region: PilI; pfam10623
1133852014924	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
1133852014925	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cl02766
1133852014926	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1133852014927	Ash protein family; Region: Phage_ASH; pfam10554
1133852014928	IncFII RepA protein family; Region: IncFII_repA; cl11495
1133852014929	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
1133852014930	putative kissing complex interaction region; other site
1133852014931	putative RNA binding sites [nucleotide binding]; other site
1133852014932	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
1133852014933	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
1133852014934	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191
1133852014935	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
1133852014936	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1133852014937	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
1133852014938	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1133852014939	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133852014940	catalytic residues [active]
1133852014941	catalytic nucleophile [active]
1133852014942	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133852014943	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133852014944	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133852014945	Synaptic Site I dimer interface [polypeptide binding]; other site
1133852014946	DNA binding site [nucleotide binding]
1133852014947	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cl17393
1133852014948	beta-lactamase TEM; Provisional; Region: PRK15442
1133852014949	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
1133852014950	ParA-like protein; Provisional; Region: PHA02518
1133852014951	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1133852014952	Magnesium ion binding site [ion binding]; other site
1133852014953	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1133852014954	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1133852014955	active site
1133852014956	DNA binding site [nucleotide binding]
1133852014957	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1133852014958	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852014959	Catalytic site [active]
1133852014960	DinI-like family; Region: DinI; pfam06183
1133852014961	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
1133852014962	putative methylase; Provisional; Region: PRK13699
1133852014963	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1133852014964	Antirestriction protein; Region: Antirestrict; pfam03230
1133852014965	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1133852014966	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1133852014967	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1133852014968	dimer interface [polypeptide binding]; other site
1133852014969	ssDNA binding site [nucleotide binding]; other site
1133852014970	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1133852014971	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1133852014972	ParB-like nuclease domain; Region: ParBc; pfam02195
1133852014973	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1133852014974	KorB domain; Region: KorB; pfam08535
1133852014975	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
1133852014976	PsiA protein; Region: PsiA; pfam06952
1133852014977	Antirestriction protein (ArdA); Region: ArdA; pfam07275
1133852014978	sensory histidine kinase CreC; Provisional; Region: PRK11100
1133852014979	hypothetical protein; Provisional; Region: PRK09956
1133852014980	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1133852014981	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1133852014982	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1133852014983	non-specific DNA binding site [nucleotide binding]; other site
1133852014984	salt bridge; other site
1133852014985	sequence-specific DNA binding site [nucleotide binding]; other site
1133852014986	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1133852014987	conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877
1133852014988	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1133852014989	Relaxase/Mobilisation nuclease domain; Region: Relaxase; cl19391
1133852014990	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1133852014991	dimerization domain [polypeptide binding]; other site
1133852014992	dimer interface [polypeptide binding]; other site
1133852014993	catalytic residues [active]
1133852014994	Hok/gef family; Region: HOK_GEF; pfam01848
1133852014995	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1133852014996	Haemolysin expression modulating protein; Region: HHA; cl11501
1133852014997	conjugal transfer/type IV secretion protein DotA/TraY; Region: DotA_TraY; TIGR04346
1133852014998	Immunoglobulin domain; Region: Ig; cl11960
1133852014999	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cl18951
1133852015000	Helix-turn-helix domain; Region: HTH_36; pfam13730
1133852015001	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852015002	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852015003	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852015004	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1133852015005	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1133852015006	putative active site [active]
1133852015007	putative NTP binding site [chemical binding]; other site
1133852015008	putative nucleic acid binding site [nucleotide binding]; other site
1133852015009	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1133852015010	COG2801 Transposase and inactivated derivatives
1133852015011	Transposase; Region: HTH_Tnp_1; cl17663
1133852015012	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015013	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1133852015014	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1133852015015	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852015016	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852015017	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852015018	Transposase; Region: HTH_Tnp_1; cl17663
1133852015019	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852015020	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852015021	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852015022	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852015023	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852015024	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852015025	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133852015026	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1133852015027	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cd00385
1133852015028	substrate binding pocket [chemical binding]; other site
1133852015029	aspartate-rich region 2; other site
1133852015030	substrate-Mg2+ binding site; other site
1133852015031	Helix-turn-helix domain; Region: HTH_28; pfam13518
1133852015032	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015033	Transposase; Region: HTH_Tnp_1; cl17663
1133852015034	putative transposase OrfB; Reviewed; Region: PHA02517
1133852015035	Integrase core domain; Region: rve_3; pfam13683
1133852015036	Integrase core domain; Region: rve; pfam00665
1133852015037	potential frameshift: common BLAST hit: gi|218706542|ref|YP_002414061.1| putative transposase ORF 1, IS66 family
1133852015038	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852015039	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852015040	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015041	Transposase; Region: HTH_Tnp_1; pfam01527
1133852015042	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1133852015043	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1133852015044	Enterobacteria AfaD invasin protein; Region: AfaD; pfam05775
1133852015045	PapC N-terminal domain; Region: PapC_N; pfam13954
1133852015046	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1133852015047	Outer membrane usher protein; Region: Usher; pfam00577
1133852015048	PapC C-terminal domain; Region: PapC_C; pfam13953
1133852015049	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
1133852015050	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
1133852015051	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1133852015052	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1133852015053	Presynaptic Site I dimer interface [polypeptide binding]; other site
1133852015054	catalytic residues [active]
1133852015055	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1133852015056	Synaptic Flat tetramer interface [polypeptide binding]; other site
1133852015057	Synaptic Site I dimer interface [polypeptide binding]; other site
1133852015058	DNA binding site [nucleotide binding]
1133852015059	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1133852015060	Catalytic site [active]
1133852015061	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1133852015062	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1133852015063	active site
1133852015064	DNA binding site [nucleotide binding]
1133852015065	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1133852015066	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
1133852015067	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1133852015068	Mg binding site [ion binding]; other site
1133852015069	nucleotide binding site [chemical binding]; other site
1133852015070	putative protofilament interface [polypeptide binding]; other site
1133852015071	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1133852015072	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1133852015073	P-loop; other site
1133852015074	Magnesium ion binding site [ion binding]; other site
1133852015075	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1133852015076	active site
1133852015077	catalytic residues [active]
1133852015078	DNA binding site [nucleotide binding]
1133852015079	Int/Topo IB signature motif; other site
1133852015080	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
1133852015081	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
1133852015082	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1133852015083	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1133852015084	oligomeric interface; other site
1133852015085	putative active site [active]
1133852015086	homodimer interface [polypeptide binding]; other site
1133852015087	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852015088	Initiator Replication protein; Region: Rep_3; pfam01051
1133852015089	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1133852015090	active site
1133852015091	catalytic residues [active]
1133852015092	DNA binding site [nucleotide binding]
1133852015093	Int/Topo IB signature motif; other site
1133852015094	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1133852015095	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1133852015096	Predicted transcriptional regulator [Transcription]; Region: COG3905
1133852015097	IncFII RepA protein family; Region: IncFII_repA; cl11495
1133852015098	IncFII RepA protein family; Region: IncFII_repA; cl11495
1133852015099	leader peptide RepL; Provisional; Region: PRK13716
1133852015100	replication protein; Provisional; Region: PRK13702
1133852015101	Transposase domain (DUF772); Region: DUF772; pfam05598
1133852015102	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1133852015103	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
1133852015104	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1133852015105	Transposase; Region: HTH_Tnp_1; pfam01527
1133852015106	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015107	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852015108	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852015109	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133852015110	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852015111	zinc-finger binding domain of transposase IS66; Region: zf-IS66; pfam13005
1133852015112	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852015113	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852015114	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852015115	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852015116	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852015117	Transposase; Region: HTH_Tnp_1; pfam01527
1133852015118	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015119	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
1133852015120	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
1133852015121	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
1133852015122	putative kissing complex interaction region; other site
1133852015123	putative RNA binding sites [nucleotide binding]; other site
1133852015124	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
1133852015125	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK14712
1133852015126	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK14712
1133852015127	AAA domain; Region: AAA_30; pfam13604
1133852015128	DNA helicase TraI; Region: TraI; pfam07057
1133852015129	TrwC relaxase; Region: TrwC; cl19905
1133852015130	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1133852015131	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1133852015132	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1133852015133	COG1662 Transposase and inactivated derivatives, IS1 family
1133852015134	TraM protein, DNA-binding; Region: Tra_M; pfam05261
1133852015135	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1133852015136	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1133852015137	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1133852015138	catalytic residue [active]
1133852015139	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1133852015140	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1133852015141	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1133852015142	catalytic residues [active]
1133852015143	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1133852015144	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1133852015145	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1133852015146	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1133852015147	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1133852015148	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852015149	Transposase; Region: HTH_Tnp_1; pfam01527
1133852015150	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015151	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852015152	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1133852015153	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1133852015154	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1133852015155	zinc-finger binding domain of transposase IS66; Region: zf-IS66; pfam13005
1133852015156	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1133852015157	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1133852015158	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1133852015159	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1133852015160	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1133852015161	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1133852015162	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1133852015163	Walker A/P-loop; other site
1133852015164	ATP binding site [chemical binding]; other site
1133852015165	Q-loop/lid; other site
1133852015166	ABC transporter signature motif; other site
1133852015167	Walker B; other site
1133852015168	D-loop; other site
1133852015169	H-loop/switch region; other site
1133852015170	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1133852015171	Uncharacterized conserved protein [Function unknown]; Region: COG2433
1133852015172	FtsX-like permease family; Region: FtsX; pfam02687
1133852015173	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1133852015174	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1133852015175	Transposase; Region: HTH_Tnp_1; cl17663
1133852015176	potential frameshift: common BLAST hit: gi|13449013|ref|NP_085229.1| secreted protease