-- dump date 20140619_085626 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 574521000001 SEQ_END SEQ_END NC_011601.1 4965553 4965553 DR NC_011601.1; contig end 4965553..4965553 Escherichia coli O127:H6 str. E2348/69 574521000002 SEQ_END SEQ_END NC_011602.1 6147 6147 DR NC_011602.1; contig end 6147..6147 Escherichia coli O127:H6 str. E2348/69 574521000003 SEQ_END SEQ_END NC_011603.1 97978 97978 DR NC_011603.1; contig end 97978..97978 Escherichia coli O127:H6 str. E2348/69 YP_002327593.1 CDS thrL NC_011601.1 190 255 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 190..255 Escherichia coli O127:H6 str. E2348/69 7062056 YP_002327594.1 CDS thrA NC_011601.1 336 2798 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 336..2798 Escherichia coli O127:H6 str. E2348/69 7061796 YP_002327595.1 CDS thrB NC_011601.1 2800 3732 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2800..3732 Escherichia coli O127:H6 str. E2348/69 7061793 YP_002327596.1 CDS thrC NC_011601.1 3733 5019 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3733..5019 Escherichia coli O127:H6 str. E2348/69 7061794 YP_002327597.1 CDS yaaX NC_011601.1 5233 5529 D hypothetical protein 5233..5529 Escherichia coli O127:H6 str. E2348/69 7061795 YP_002327598.1 CDS yaaA NC_011601.1 5579 6355 R hypothetical protein complement(5579..6355) Escherichia coli O127:H6 str. E2348/69 7064881 YP_002327599.1 CDS yaaJ NC_011601.1 6425 7855 R transporter complement(6425..7855) Escherichia coli O127:H6 str. E2348/69 7064875 YP_002327600.1 CDS talB NC_011601.1 8134 9087 D transaldolase B 8134..9087 Escherichia coli O127:H6 str. E2348/69 7064878 YP_002327601.1 CDS mogA NC_011601.1 9202 9789 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9202..9789 Escherichia coli O127:H6 str. E2348/69 7061750 YP_002327602.1 CDS E2348C_0010 NC_011601.1 9973 11346 D transposase of ISEc13 9973..11346 Escherichia coli O127:H6 str. E2348/69 7064960 YP_002327603.1 CDS yaaH NC_011601.1 11382 11948 R hypothetical protein complement(11382..11948) Escherichia coli O127:H6 str. E2348/69 7062057 YP_002327604.1 CDS yaaW NC_011601.1 12097 12810 R hypothetical protein complement(12097..12810) Escherichia coli O127:H6 str. E2348/69 7064876 YP_002327605.1 CDS yaaI NC_011601.1 12836 13240 R hypothetical protein complement(12836..13240) Escherichia coli O127:H6 str. E2348/69 7064880 YP_002327606.1 CDS dnaK NC_011601.1 13612 15528 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 13612..15528 Escherichia coli O127:H6 str. E2348/69 7064877 YP_002327607.1 CDS dnaJ NC_011601.1 15617 16747 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 15617..16747 Escherichia coli O127:H6 str. E2348/69 7065050 YP_002327608.1 CDS mokC1 NC_011601.1 16852 17061 R regulatory protein MokC for HokC 1 complement(16852..17061) Escherichia coli O127:H6 str. E2348/69 7065049 YP_002327609.1 CDS hokC1 NC_011601.1 16852 17004 R small toxic membrane peptide HokC 1 complement(16852..17004) Escherichia coli O127:H6 str. E2348/69 7063819 YP_002327610.1 CDS E2348C_0018 NC_011601.1 17619 18380 D hypothetical protein 17619..18380 Escherichia coli O127:H6 str. E2348/69 7062736 YP_002327611.1 CDS E2348C_0019 NC_011601.1 18401 19894 D arylsulfatase 18401..19894 Escherichia coli O127:H6 str. E2348/69 7063424 YP_002327612.1 CDS E2348C_0020 NC_011601.1 20023 21282 D hypothetical protein 20023..21282 Escherichia coli O127:H6 str. E2348/69 7063425 YP_002327613.1 CDS nhaA NC_011601.1 21517 22683 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 21517..22683 Escherichia coli O127:H6 str. E2348/69 7063426 YP_002327614.1 CDS nhaR NC_011601.1 22743 23648 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 22743..23648 Escherichia coli O127:H6 str. E2348/69 7065387 YP_002327615.1 CDS rpsT NC_011601.1 23744 24007 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(23744..24007) Escherichia coli O127:H6 str. E2348/69 7065389 YP_002327616.1 CDS yaaY NC_011601.1 24110 24328 D hypothetical protein 24110..24328 Escherichia coli O127:H6 str. E2348/69 7061892 YP_002327617.1 CDS ribF NC_011601.1 24336 25277 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 24336..25277 Escherichia coli O127:H6 str. E2348/69 7064882 YP_002327618.1 CDS ileS NC_011601.1 25320 28136 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 25320..28136 Escherichia coli O127:H6 str. E2348/69 7060823 YP_002327619.1 CDS lspA NC_011601.1 28136 28630 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 28136..28630 Escherichia coli O127:H6 str. E2348/69 7063523 YP_002327620.1 CDS fkpB NC_011601.1 28738 29187 D FKBP-type peptidylprolyl isomerase 28738..29187 Escherichia coli O127:H6 str. E2348/69 7065247 YP_002327621.1 CDS ispH NC_011601.1 29189 30139 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 29189..30139 Escherichia coli O127:H6 str. E2348/69 7062135 YP_002327622.1 CDS rihC NC_011601.1 30205 31119 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 30205..31119 Escherichia coli O127:H6 str. E2348/69 7063557 YP_002327623.1 CDS dapB NC_011601.1 31286 32107 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 31286..32107 Escherichia coli O127:H6 str. E2348/69 7060826 YP_002327624.1 CDS carA NC_011601.1 32563 33711 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 32563..33711 Escherichia coli O127:H6 str. E2348/69 7065221 YP_002327625.1 CDS carB NC_011601.1 33729 36950 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 33729..36950 Escherichia coli O127:H6 str. E2348/69 7064324 YP_002327626.1 CDS E2348C_0034 NC_011601.1 36958 37176 R hypothetical protein complement(36958..37176) Escherichia coli O127:H6 str. E2348/69 7064325 YP_002327627.1 CDS caiF NC_011601.1 37211 37606 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 37211..37606 Escherichia coli O127:H6 str. E2348/69 7063427 YP_002327628.1 CDS caiE NC_011601.1 37725 38315 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(37725..38315) Escherichia coli O127:H6 str. E2348/69 7064321 YP_002327629.2 CDS caiD NC_011601.1 38321 39106 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(38321..39106) Escherichia coli O127:H6 str. E2348/69 7064320 YP_002327630.1 CDS caiC NC_011601.1 39215 40768 R crotonobetaine/carnitine-CoA ligase complement(39215..40768) Escherichia coli O127:H6 str. E2348/69 7064319 YP_002327631.1 CDS caiB NC_011601.1 40841 42058 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(40841..42058) Escherichia coli O127:H6 str. E2348/69 7064318 YP_002327632.1 CDS caiA NC_011601.1 42176 43318 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(42176..43318) Escherichia coli O127:H6 str. E2348/69 7064317 YP_002327633.1 CDS caiT NC_011601.1 43349 44863 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(43349..44863) Escherichia coli O127:H6 str. E2348/69 7064316 YP_002327634.1 CDS fixA NC_011601.1 45277 46047 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45277..46047 Escherichia coli O127:H6 str. E2348/69 7064322 YP_002327635.1 CDS fixB NC_011601.1 46062 47003 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 46062..47003 Escherichia coli O127:H6 str. E2348/69 7062130 YP_002327636.1 CDS fixC NC_011601.1 47054 48340 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 47054..48340 Escherichia coli O127:H6 str. E2348/69 7062131 YP_002327637.1 CDS fixX NC_011601.1 48337 48624 D 4Fe-4S ferredoxin 48337..48624 Escherichia coli O127:H6 str. E2348/69 7062132 YP_002327638.1 CDS yaaU NC_011601.1 48683 50014 D transporter 48683..50014 Escherichia coli O127:H6 str. E2348/69 7062133 YP_002327639.1 CDS kefF NC_011601.1 50122 50652 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 50122..50652 Escherichia coli O127:H6 str. E2348/69 7064879 YP_002327640.1 CDS kefC NC_011601.1 50645 52507 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 50645..52507 Escherichia coli O127:H6 str. E2348/69 7061502 YP_002327641.1 CDS folA NC_011601.1 52699 53178 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52699..53178 Escherichia coli O127:H6 str. E2348/69 7061501 YP_002327642.1 CDS E2348C_0050 NC_011601.1 53264 53497 D CcdA-like protein 53264..53497 Escherichia coli O127:H6 str. E2348/69 7061938 YP_002327643.1 CDS E2348C_0051 NC_011601.1 53500 53814 D CcdB-like protein 53500..53814 Escherichia coli O127:H6 str. E2348/69 7063428 YP_002327644.1 CDS apaH NC_011601.1 53811 54659 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(53811..54659) Escherichia coli O127:H6 str. E2348/69 7063429 YP_002327645.1 CDS apaG NC_011601.1 54666 55043 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(54666..55043) Escherichia coli O127:H6 str. E2348/69 7061348 YP_002327646.1 CDS ksgA NC_011601.1 55046 55867 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(55046..55867) Escherichia coli O127:H6 str. E2348/69 7061347 YP_002327647.1 CDS pdxA NC_011601.1 55864 56853 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(55864..56853) Escherichia coli O127:H6 str. E2348/69 7061506 YP_002327648.1 CDS surA NC_011601.1 56853 58139 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(56853..58139) Escherichia coli O127:H6 str. E2348/69 7062939 YP_002327649.1 CDS imp NC_011601.1 58192 60546 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(58192..60546) Escherichia coli O127:H6 str. E2348/69 7061744 YP_002327650.1 CDS djlA NC_011601.1 60801 61616 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 60801..61616 Escherichia coli O127:H6 str. E2348/69 7063540 YP_002327651.1 CDS rluA NC_011601.1 61734 62393 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(61734..62393) Escherichia coli O127:H6 str. E2348/69 7065035 YP_002327652.1 CDS hepA NC_011601.1 62405 65311 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(62405..65311) Escherichia coli O127:H6 str. E2348/69 7060838 YP_002327653.1 CDS polB NC_011601.1 65476 67827 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(65476..67827) Escherichia coli O127:H6 str. E2348/69 7064303 YP_002327654.1 CDS araD NC_011601.1 67902 68597 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(67902..68597) Escherichia coli O127:H6 str. E2348/69 7060769 YP_002327655.1 CDS araA NC_011601.1 68712 70214 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(68712..70214) Escherichia coli O127:H6 str. E2348/69 7061359 YP_002327656.1 CDS araB NC_011601.1 70225 71925 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(70225..71925) Escherichia coli O127:H6 str. E2348/69 7061356 YP_002327657.1 CDS araC NC_011601.1 72264 73109 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 72264..73109 Escherichia coli O127:H6 str. E2348/69 7061357 YP_002327658.1 CDS E2348C_0066 NC_011601.1 73334 74566 D ribokinase 73334..74566 Escherichia coli O127:H6 str. E2348/69 7061358 YP_002327659.1 CDS E2348C_0067 NC_011601.1 74592 75515 D dihydrodipicolinate synthetase 74592..75515 Escherichia coli O127:H6 str. E2348/69 7063430 YP_002327660.1 CDS E2348C_0068 NC_011601.1 75570 76523 D hypothetical protein 75570..76523 Escherichia coli O127:H6 str. E2348/69 7063431 YP_002327661.1 CDS E2348C_0069 NC_011601.1 76572 77009 D hypothetical protein 76572..77009 Escherichia coli O127:H6 str. E2348/69 7063432 YP_002327662.1 CDS E2348C_0070 NC_011601.1 77019 78506 D hypothetical protein 77019..78506 Escherichia coli O127:H6 str. E2348/69 7063433 YP_002327663.1 CDS yabI NC_011601.1 78690 79454 D hypothetical protein 78690..79454 Escherichia coli O127:H6 str. E2348/69 7063434 YP_002327664.1 CDS thiQ NC_011601.1 79568 80266 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(79568..80266) Escherichia coli O127:H6 str. E2348/69 7064883 YP_002327665.1 CDS thiP NC_011601.1 80250 81860 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(80250..81860) Escherichia coli O127:H6 str. E2348/69 7061791 YP_002327666.1 CDS tbpA NC_011601.1 81836 82819 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(81836..82819) Escherichia coli O127:H6 str. E2348/69 7061790 YP_002327667.1 CDS sgrR NC_011601.1 82983 84638 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(82983..84638) Escherichia coli O127:H6 str. E2348/69 7061143 YP_002327668.1 CDS leuD NC_011601.1 84966 85571 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(84966..85571) Escherichia coli O127:H6 str. E2348/69 7062715 YP_002327669.1 CDS leuC NC_011601.1 85582 86982 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(85582..86982) Escherichia coli O127:H6 str. E2348/69 7061524 YP_002327670.1 CDS leuB NC_011601.1 86985 88076 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(86985..88076) Escherichia coli O127:H6 str. E2348/69 7061523 YP_002327671.1 CDS leuA NC_011601.1 88076 89647 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(88076..89647) Escherichia coli O127:H6 str. E2348/69 7061522 YP_002327672.1 CDS leuL NC_011601.1 89740 89826 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(89740..89826) Escherichia coli O127:H6 str. E2348/69 7061521 YP_002327673.1 CDS leuO NC_011601.1 90485 91429 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 90485..91429 Escherichia coli O127:H6 str. E2348/69 7061526 YP_002327674.1 CDS ilvI NC_011601.1 91747 93471 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 91747..93471 Escherichia coli O127:H6 str. E2348/69 7061527 YP_002327675.1 CDS ilvH NC_011601.1 93474 93965 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 93474..93965 Escherichia coli O127:H6 str. E2348/69 7063535 YP_002327677.1 CDS fruR NC_011601.1 94145 95149 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 94145..95149 Escherichia coli O127:H6 str. E2348/69 7063435 YP_002327678.1 CDS mraZ NC_011601.1 95751 96209 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 95751..96209 Escherichia coli O127:H6 str. E2348/69 7061962 YP_002327679.1 CDS mraW NC_011601.1 96211 97152 D S-adenosyl-methyltransferase MraW 96211..97152 Escherichia coli O127:H6 str. E2348/69 7060862 YP_002327680.1 CDS ftsL NC_011601.1 97149 97514 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 97149..97514 Escherichia coli O127:H6 str. E2348/69 7060859 YP_002327681.1 CDS ftsI NC_011601.1 97530 99296 D transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 97530..99296 Escherichia coli O127:H6 str. E2348/69 7061586 YP_002327682.1 CDS murE NC_011601.1 99283 100770 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 99283..100770 Escherichia coli O127:H6 str. E2348/69 7061584 YP_002327683.1 CDS murF NC_011601.1 100767 102125 D UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 100767..102125 Escherichia coli O127:H6 str. E2348/69 7060891 YP_002327684.1 CDS mraY NC_011601.1 102119 103201 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 102119..103201 Escherichia coli O127:H6 str. E2348/69 7060892 YP_002327685.1 CDS murD NC_011601.1 103204 104520 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 103204..104520 Escherichia coli O127:H6 str. E2348/69 7060861 YP_002327686.1 CDS ftsW NC_011601.1 104520 105764 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 104520..105764 Escherichia coli O127:H6 str. E2348/69 7060890 YP_002327687.1 CDS murG NC_011601.1 105761 106828 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 105761..106828 Escherichia coli O127:H6 str. E2348/69 7061589 YP_002327688.1 CDS murC NC_011601.1 106882 108357 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 106882..108357 Escherichia coli O127:H6 str. E2348/69 7060893 YP_002327689.1 CDS ddl NC_011601.1 108350 109270 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 108350..109270 Escherichia coli O127:H6 str. E2348/69 7060889 YP_002327690.1 CDS ftsQ NC_011601.1 109272 110102 D involved in septum formation; cell division protein FtsQ 109272..110102 Escherichia coli O127:H6 str. E2348/69 7065238 YP_002327691.1 CDS ftsA NC_011601.1 110099 111361 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 110099..111361 Escherichia coli O127:H6 str. E2348/69 7061588 YP_002327692.1 CDS ftsZ NC_011601.1 111422 112573 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 111422..112573 Escherichia coli O127:H6 str. E2348/69 7061581 YP_002327693.1 CDS lpxC NC_011601.1 112674 113591 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 112674..113591 Escherichia coli O127:H6 str. E2348/69 7061592 YP_002327694.1 CDS secM NC_011601.1 113821 114333 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 113821..114333 Escherichia coli O127:H6 str. E2348/69 7061574 YP_002327695.1 CDS secA NC_011601.1 114395 117100 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 114395..117100 Escherichia coli O127:H6 str. E2348/69 7065358 YP_002327696.1 CDS mutT NC_011601.1 117160 117558 D nucleoside triphosphate pyrophosphohydrolase 117160..117558 Escherichia coli O127:H6 str. E2348/69 7065352 YP_002327697.1 CDS yacG NC_011601.1 117646 117843 R zinc-binding protein complement(117646..117843) Escherichia coli O127:H6 str. E2348/69 7060901 YP_002327698.1 CDS yacF NC_011601.1 117853 118596 R hypothetical protein complement(117853..118596) Escherichia coli O127:H6 str. E2348/69 7064886 YP_002327699.1 CDS coaE NC_011601.1 118596 119216 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(118596..119216) Escherichia coli O127:H6 str. E2348/69 7064885 YP_002327700.1 CDS guaC NC_011601.1 119442 120485 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 119442..120485 Escherichia coli O127:H6 str. E2348/69 7062823 YP_002327701.1 CDS hofC NC_011601.1 120520 121722 R type IV pilin biogenesis protein complement(120520..121722) Escherichia coli O127:H6 str. E2348/69 7064272 YP_002327702.1 CDS hofB NC_011601.1 121712 123097 R hypothetical protein complement(121712..123097) Escherichia coli O127:H6 str. E2348/69 7062162 YP_002327703.1 CDS ppdD NC_011601.1 123107 123547 R major pilin subunit complement(123107..123547) Escherichia coli O127:H6 str. E2348/69 7062161 YP_002327704.1 CDS nadC NC_011601.1 123751 124644 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(123751..124644) Escherichia coli O127:H6 str. E2348/69 7061267 YP_002327705.1 CDS ampD NC_011601.1 124732 125283 D N-acetyl-anhydromuranmyl-L-alanine amidase 124732..125283 Escherichia coli O127:H6 str. E2348/69 7060906 YP_002327706.1 CDS ampE NC_011601.1 125280 126134 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 125280..126134 Escherichia coli O127:H6 str. E2348/69 7062457 YP_002327707.1 CDS aroP NC_011601.1 126177 127550 R aromatic amino acid transporter complement(126177..127550) Escherichia coli O127:H6 str. E2348/69 7062458 YP_002327708.1 CDS pdhR NC_011601.1 128091 128855 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 128091..128855 Escherichia coli O127:H6 str. E2348/69 7061400 YP_002327709.1 CDS aceE NC_011601.1 129016 131679 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 129016..131679 Escherichia coli O127:H6 str. E2348/69 7062918 YP_002327710.1 CDS aceF NC_011601.1 131694 133586 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 131694..133586 Escherichia coli O127:H6 str. E2348/69 7062386 YP_002327711.1 CDS lpd NC_011601.1 133794 135218 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 133794..135218 Escherichia coli O127:H6 str. E2348/69 7062387 YP_002327712.1 CDS yacH NC_011601.1 135289 137142 R hypothetical protein complement(135289..137142) Escherichia coli O127:H6 str. E2348/69 7061561 YP_002327713.1 CDS acnB NC_011601.1 137497 140094 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 137497..140094 Escherichia coli O127:H6 str. E2348/69 7064887 YP_002327714.1 CDS yacL NC_011601.1 140269 140631 D hypothetical protein 140269..140631 Escherichia coli O127:H6 str. E2348/69 7062391 YP_002327715.1 CDS speD NC_011601.1 140669 141463 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(140669..141463) Escherichia coli O127:H6 str. E2348/69 7064888 YP_002327716.1 CDS speE NC_011601.1 141479 142345 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(141479..142345) Escherichia coli O127:H6 str. E2348/69 7062743 YP_002327717.1 CDS yacC NC_011601.1 142451 142798 R hypothetical protein complement(142451..142798) Escherichia coli O127:H6 str. E2348/69 7062744 YP_002327718.1 CDS cueO NC_011601.1 142964 144514 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 142964..144514 Escherichia coli O127:H6 str. E2348/69 7064884 YP_002327719.1 CDS gcd NC_011601.1 144561 146951 R glucose dehydrogenase complement(144561..146951) Escherichia coli O127:H6 str. E2348/69 7065167 YP_002327720.1 CDS hpt NC_011601.1 147157 147693 D hypoxanthine phosphoribosyltransferase 147157..147693 Escherichia coli O127:H6 str. E2348/69 7061639 YP_002327721.1 CDS can NC_011601.1 147734 148396 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(147734..148396) Escherichia coli O127:H6 str. E2348/69 7062177 YP_002327722.1 CDS yadG NC_011601.1 148505 149431 D transporter subunit: ATP-binding component of ABC superfamily 148505..149431 Escherichia coli O127:H6 str. E2348/69 7064323 YP_002327723.1 CDS yadH NC_011601.1 149428 150198 D transporter subunit: membrane component of ABC superfamily 149428..150198 Escherichia coli O127:H6 str. E2348/69 7064893 YP_002327724.1 CDS yadI NC_011601.1 150303 150743 D PTS Enzyme IIA 150303..150743 Escherichia coli O127:H6 str. E2348/69 7064894 YP_002327725.1 CDS yadE NC_011601.1 150807 152036 D polysaccharide deacetylase 150807..152036 Escherichia coli O127:H6 str. E2348/69 7064895 YP_002327726.1 CDS panD NC_011601.1 152040 152420 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(152040..152420) Escherichia coli O127:H6 str. E2348/69 7064892 YP_002327727.1 CDS yadD NC_011601.1 152694 153662 D transposase 152694..153662 Escherichia coli O127:H6 str. E2348/69 7062908 YP_002327728.1 CDS panC NC_011601.1 153744 154595 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(153744..154595) Escherichia coli O127:H6 str. E2348/69 7064891 YP_002327729.1 CDS panB NC_011601.1 154607 155401 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(154607..155401) Escherichia coli O127:H6 str. E2348/69 7062907 YP_002327730.1 CDS yadK NC_011601.1 156830 157426 R fimbrial protein complement(156830..157426) Escherichia coli O127:H6 str. E2348/69 7064890 YP_002327731.1 CDS htrE NC_011601.1 158655 161243 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(158655..161243) Escherichia coli O127:H6 str. E2348/69 7064898 YP_002327732.1 CDS yadN NC_011601.1 162128 162718 R fimbrial-like protein complement(162128..162718) Escherichia coli O127:H6 str. E2348/69 7063833 YP_002327733.1 CDS folK NC_011601.1 163077 163556 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(163077..163556) Escherichia coli O127:H6 str. E2348/69 7064899 YP_002327734.1 CDS pcnB NC_011601.1 163553 164917 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase complement(163553..164917) Escherichia coli O127:H6 str. E2348/69 7061943 YP_002327735.1 CDS yadB NC_011601.1 165010 165936 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(165010..165936) Escherichia coli O127:H6 str. E2348/69 7062917 YP_002327736.1 CDS dksA NC_011601.1 165973 166428 R RNA polymerase-binding transcription factor complement(165973..166428) Escherichia coli O127:H6 str. E2348/69 7064889 YP_002327737.1 CDS sfsA NC_011601.1 166606 167310 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(166606..167310) Escherichia coli O127:H6 str. E2348/69 7065038 YP_002327738.1 CDS ligT NC_011601.1 167325 167855 R 2'-5' RNA ligase complement(167325..167855) Escherichia coli O127:H6 str. E2348/69 7062709 YP_002327739.1 CDS hrpB NC_011601.1 167929 170358 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 167929..170358 Escherichia coli O127:H6 str. E2348/69 7061541 YP_002327740.1 CDS mrcB NC_011601.1 170452 172986 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 170452..172986 Escherichia coli O127:H6 str. E2348/69 7062179 YP_002327741.1 CDS E2348C_0153 NC_011601.1 173313 173879 D fimbrial protein 173313..173879 Escherichia coli O127:H6 str. E2348/69 7060864 YP_002327742.1 CDS E2348C_0155 NC_011601.1 174685 177162 D fimbrial outer membrane usher protein 174685..177162 Escherichia coli O127:H6 str. E2348/69 7063437 YP_002327743.1 CDS E2348C_0156 NC_011601.1 177184 178194 D fimbrial protein 177184..178194 Escherichia coli O127:H6 str. E2348/69 7063438 YP_002327744.1 CDS fhuA NC_011601.1 178415 180610 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 178415..180610 Escherichia coli O127:H6 str. E2348/69 7063439 YP_002327745.1 CDS fhuC NC_011601.1 180661 181458 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 180661..181458 Escherichia coli O127:H6 str. E2348/69 7062111 YP_002327746.1 CDS fhuD NC_011601.1 181458 182348 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 181458..182348 Escherichia coli O127:H6 str. E2348/69 7062113 YP_002327747.1 CDS fhuB NC_011601.1 182345 184327 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 182345..184327 Escherichia coli O127:H6 str. E2348/69 7062114 YP_002327748.1 CDS hemL NC_011601.1 184362 185642 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(184362..185642) Escherichia coli O127:H6 str. E2348/69 7062112 YP_002327749.1 CDS clcA NC_011601.1 185867 187288 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 185867..187288 Escherichia coli O127:H6 str. E2348/69 7064299 YP_002327750.1 CDS yadR NC_011601.1 187370 187714 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 187370..187714 Escherichia coli O127:H6 str. E2348/69 7062806 YP_002327751.1 CDS yadS NC_011601.1 187761 188384 R hypothetical protein complement(187761..188384) Escherichia coli O127:H6 str. E2348/69 7064900 YP_002327752.1 CDS btuF NC_011601.1 188422 189222 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(188422..189222) Escherichia coli O127:H6 str. E2348/69 7064901 YP_002327753.1 CDS pfs NC_011601.1 189215 189913 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(189215..189913) Escherichia coli O127:H6 str. E2348/69 7064311 YP_002327754.1 CDS dgt NC_011601.1 189997 191514 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 189997..191514 Escherichia coli O127:H6 str. E2348/69 7060712 YP_002327755.1 CDS degP NC_011601.1 191644 193068 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 191644..193068 Escherichia coli O127:H6 str. E2348/69 7065020 YP_002327756.1 CDS cdaR NC_011601.1 193223 194380 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 193223..194380 Escherichia coli O127:H6 str. E2348/69 7065003 YP_002327757.1 CDS yaeH NC_011601.1 194433 194819 R hypothetical protein complement(194433..194819) Escherichia coli O127:H6 str. E2348/69 7064340 YP_002327758.1 CDS dapD NC_011601.1 195129 195953 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(195129..195953) Escherichia coli O127:H6 str. E2348/69 7064904 YP_002327759.1 CDS glnD NC_011601.1 195984 198656 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(195984..198656) Escherichia coli O127:H6 str. E2348/69 7065222 YP_002327760.1 CDS map NC_011601.1 198718 199512 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(198718..199512) Escherichia coli O127:H6 str. E2348/69 7061678 YP_002327761.1 CDS rpsB NC_011601.1 199880 200605 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 199880..200605 Escherichia coli O127:H6 str. E2348/69 7061778 YP_002327762.1 CDS tsf NC_011601.1 200863 201714 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 200863..201714 Escherichia coli O127:H6 str. E2348/69 7061874 YP_002327763.1 CDS pyrH NC_011601.1 201861 202586 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 201861..202586 Escherichia coli O127:H6 str. E2348/69 7062270 YP_002327764.1 CDS frr NC_011601.1 202878 203435 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 202878..203435 Escherichia coli O127:H6 str. E2348/69 7063935 YP_002327765.1 CDS dxr NC_011601.1 203527 204723 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 203527..204723 Escherichia coli O127:H6 str. E2348/69 7061957 YP_002327766.1 CDS ispU NC_011601.1 204909 205670 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 204909..205670 Escherichia coli O127:H6 str. E2348/69 7065075 YP_002327767.1 CDS cdsA NC_011601.1 205713 206540 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 205713..206540 Escherichia coli O127:H6 str. E2348/69 7063558 YP_002327768.1 CDS yaeL NC_011601.1 206552 207904 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 206552..207904 Escherichia coli O127:H6 str. E2348/69 7064343 YP_002327769.1 CDS yaeT NC_011601.1 207934 210366 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 207934..210366 Escherichia coli O127:H6 str. E2348/69 7064906 YP_002327770.1 CDS skp NC_011601.1 210488 210973 D periplasmic chaperone 210488..210973 Escherichia coli O127:H6 str. E2348/69 7064910 YP_002327771.1 CDS lpxD NC_011601.1 210977 212002 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 210977..212002 Escherichia coli O127:H6 str. E2348/69 7062719 YP_002327772.1 CDS fabZ NC_011601.1 212107 212562 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 212107..212562 Escherichia coli O127:H6 str. E2348/69 7061575 YP_002327773.1 CDS lpxA NC_011601.1 212566 213354 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 212566..213354 Escherichia coli O127:H6 str. E2348/69 7062070 YP_002327774.1 CDS lpxB NC_011601.1 213354 214502 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 213354..214502 Escherichia coli O127:H6 str. E2348/69 7061572 YP_002327775.1 CDS rnhB NC_011601.1 214499 215095 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 214499..215095 Escherichia coli O127:H6 str. E2348/69 7061573 YP_002327776.1 CDS dnaE NC_011601.1 215127 218609 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 215127..218609 Escherichia coli O127:H6 str. E2348/69 7060854 YP_002327777.1 CDS accA NC_011601.1 218622 219581 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 218622..219581 Escherichia coli O127:H6 str. E2348/69 7065047 YP_002327778.1 CDS ldcC NC_011601.1 219680 221821 D lysine decarboxylase 2, constitutive 219680..221821 Escherichia coli O127:H6 str. E2348/69 7062380 YP_002327779.1 CDS yaeR NC_011601.1 221878 222267 D hypothetical protein 221878..222267 Escherichia coli O127:H6 str. E2348/69 7061513 YP_002327780.1 CDS tilS NC_011601.1 222332 223645 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 222332..223645 Escherichia coli O127:H6 str. E2348/69 7064909 YP_002327781.1 CDS rof NC_011601.1 223679 223933 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(223679..223933) Escherichia coli O127:H6 str. E2348/69 7061804 YP_002327782.1 CDS yaeP NC_011601.1 223926 224126 R hypothetical protein complement(223926..224126) Escherichia coli O127:H6 str. E2348/69 7061823 YP_002327783.1 CDS yaeQ NC_011601.1 224292 224837 D hypothetical protein 224292..224837 Escherichia coli O127:H6 str. E2348/69 7064907 YP_002327784.1 CDS yaeJ NC_011601.1 224834 225256 D peptidyl-tRNA hydrolase domain-containing protein 224834..225256 Escherichia coli O127:H6 str. E2348/69 7064908 YP_002327785.1 CDS nlpE NC_011601.1 225270 225980 D lipoprotein involved with copper homeostasis and adhesion 225270..225980 Escherichia coli O127:H6 str. E2348/69 7064905 YP_002327786.1 CDS yaeF NC_011601.1 226136 226960 R hypothetical protein complement(226136..226960) Escherichia coli O127:H6 str. E2348/69 7065404 YP_002327787.1 CDS proS NC_011601.1 227013 228731 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(227013..228731) Escherichia coli O127:H6 str. E2348/69 7064903 YP_002327788.1 CDS yaeB NC_011601.1 228842 229549 R hypothetical protein complement(228842..229549) Escherichia coli O127:H6 str. E2348/69 7061304 YP_002327789.1 CDS rcsF NC_011601.1 229546 229950 R outer membrane lipoprotein complement(229546..229950) Escherichia coli O127:H6 str. E2348/69 7064902 YP_002327790.1 CDS metQ NC_011601.1 230068 230883 R DL-methionine transporter substrate-binding subunit complement(230068..230883) Escherichia coli O127:H6 str. E2348/69 7063967 YP_002327791.1 CDS metI NC_011601.1 230923 231576 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(230923..231576) Escherichia coli O127:H6 str. E2348/69 7063768 YP_002327792.1 CDS metN NC_011601.1 231569 232600 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(231569..232600) Escherichia coli O127:H6 str. E2348/69 7063763 YP_002327793.1 CDS gmhB NC_011601.1 232788 233360 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 232788..233360 Escherichia coli O127:H6 str. E2348/69 7063767 YP_002327794.1 CDS dkgB NC_011601.1 239126 239929 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 239126..239929 Escherichia coli O127:H6 str. E2348/69 7062462 YP_002327795.1 CDS yafC NC_011601.1 239926 240840 R DNA-binding transcriptional regulator complement(239926..240840) Escherichia coli O127:H6 str. E2348/69 7065037 YP_002327796.1 CDS yafD NC_011601.1 241081 241881 D hypothetical protein 241081..241881 Escherichia coli O127:H6 str. E2348/69 7064911 YP_002327797.1 CDS yafE NC_011601.1 241959 242729 D S-adenosyl-L-methionine-dependent methyltransferase 241959..242729 Escherichia coli O127:H6 str. E2348/69 7064912 YP_002327798.1 CDS mltD NC_011601.1 242778 244136 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(242778..244136) Escherichia coli O127:H6 str. E2348/69 7064913 YP_002327799.1 CDS gloB NC_011601.1 244208 244963 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(244208..244963) Escherichia coli O127:H6 str. E2348/69 7063797 YP_002327800.1 CDS yafS NC_011601.1 244997 245719 D S-adenosyl-L-methionine-dependent methyltransferase 244997..245719 Escherichia coli O127:H6 str. E2348/69 7061691 YP_002327801.1 CDS rnhA NC_011601.1 245716 246183 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(245716..246183) Escherichia coli O127:H6 str. E2348/69 7064918 YP_002327802.1 CDS dnaQ NC_011601.1 246248 246979 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 246248..246979 Escherichia coli O127:H6 str. E2348/69 7060853 YP_002327803.1 CDS yafV NC_011601.1 247287 248057 R hypothetical protein complement(247287..248057) Escherichia coli O127:H6 str. E2348/69 7062463 YP_002327804.1 CDS ivy NC_011601.1 248211 248684 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 248211..248684 Escherichia coli O127:H6 str. E2348/69 7064919 YP_002327805.1 CDS fadE NC_011601.1 248727 251171 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(248727..251171) Escherichia coli O127:H6 str. E2348/69 7063562 YP_002327806.1 CDS gmhA NC_011601.1 251411 251989 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 251411..251989 Escherichia coli O127:H6 str. E2348/69 7062074 YP_002327807.1 CDS yafJ NC_011601.1 252194 252961 D amidotransferase 252194..252961 Escherichia coli O127:H6 str. E2348/69 7061560 YP_002327808.1 CDS yafK NC_011601.1 252932 253672 R hypothetical protein complement(252932..253672) Escherichia coli O127:H6 str. E2348/69 7064914 YP_002327809.1 CDS yafL NC_011601.1 253975 254733 D lipoprotein 253975..254733 Escherichia coli O127:H6 str. E2348/69 7064915 YP_002327810.1 CDS E2348C_0223 NC_011601.1 254790 255146 R hypothetical protein complement(254790..255146) Escherichia coli O127:H6 str. E2348/69 7064916 YP_002327811.1 CDS mbhA NC_011601.1 257206 257991 D hypothetical protein 257206..257991 Escherichia coli O127:H6 str. E2348/69 7062109 YP_002327812.1 CDS dinB NC_011601.1 258062 259117 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 258062..259117 Escherichia coli O127:H6 str. E2348/69 7065296 YP_002327813.1 CDS yafP NC_011601.1 259114 259566 D hypothetical protein 259114..259566 Escherichia coli O127:H6 str. E2348/69 7065028 YP_002327814.1 CDS E2348C_0228 NC_011601.1 259757 260896 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 259757..260896 Escherichia coli O127:H6 str. E2348/69 7064917 YP_002327815.1 CDS prfH NC_011601.1 260893 261474 D similar to release factor 1 and 2; peptide chain release factor-like protein 260893..261474 Escherichia coli O127:H6 str. E2348/69 7063441 YP_002327816.1 CDS pepD NC_011601.1 261564 263021 R aminoacyl-histidine dipeptidase complement(261564..263021) Escherichia coli O127:H6 str. E2348/69 7061287 YP_002327817.1 CDS gpt NC_011601.1 263282 263740 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 263282..263740 Escherichia coli O127:H6 str. E2348/69 7060700 YP_002327818.1 CDS frsA NC_011601.1 263832 265076 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 263832..265076 Escherichia coli O127:H6 str. E2348/69 7064238 YP_002327819.1 CDS crl NC_011601.1 265134 265535 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 265134..265535 Escherichia coli O127:H6 str. E2348/69 7061958 YP_002327820.1 CDS phoE NC_011601.1 265574 266629 R outer membrane phosphoporin protein E complement(265574..266629) Escherichia coli O127:H6 str. E2348/69 7062846 YP_002327821.1 CDS proB NC_011601.1 266918 268021 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 266918..268021 Escherichia coli O127:H6 str. E2348/69 7060744 YP_002327822.1 CDS proA NC_011601.1 268033 269286 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 268033..269286 Escherichia coli O127:H6 str. E2348/69 7061297 YP_002327823.1 CDS E2348C_0238 NC_011601.1 270037 270375 D transposase Orf1 of IS3 family IS element 270037..270375 Escherichia coli O127:H6 str. E2348/69 7064961 YP_002327824.1 CDS E2348C_0240 NC_011601.1 271216 272292 D transposase of ISEc21 271216..272292 Escherichia coli O127:H6 str. E2348/69 7064962 YP_002327825.1 CDS yagU NC_011601.1 273430 274044 D hypothetical protein 273430..274044 Escherichia coli O127:H6 str. E2348/69 7063444 YP_002327826.1 CDS ykgJ NC_011601.1 274293 274622 R ferredoxin complement(274293..274622) Escherichia coli O127:H6 str. E2348/69 7064920 YP_002327827.1 CDS ecpE NC_011601.1 274935 275645 R chaperone complement(274935..275645) Escherichia coli O127:H6 str. E2348/69 7062005 YP_002327828.1 CDS ecpD NC_011601.1 275614 277257 R hypothetical protein complement(275614..277257) Escherichia coli O127:H6 str. E2348/69 7063835 YP_002327829.1 CDS ecpC NC_011601.1 277247 279772 R outer membrane usher protein complement(277247..279772) Escherichia coli O127:H6 str. E2348/69 7063834 YP_002327830.1 CDS ecpB NC_011601.1 279798 280466 R chaperone complement(279798..280466) Escherichia coli O127:H6 str. E2348/69 7063832 YP_002327831.1 CDS ecpA NC_011601.1 280523 281110 R fimbrillin precursor complement(280523..281110) Escherichia coli O127:H6 str. E2348/69 7063831 YP_002327832.1 CDS ecpR NC_011601.1 281184 281774 R regulator complement(281184..281774) Escherichia coli O127:H6 str. E2348/69 7063830 YP_002327833.1 CDS E2348C_0251 NC_011601.1 282198 282488 D hypothetical protein 282198..282488 Escherichia coli O127:H6 str. E2348/69 7063836 YP_002327834.1 CDS rpmJ NC_011601.1 282810 282950 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(282810..282950) Escherichia coli O127:H6 str. E2348/69 7062006 YP_002327835.1 CDS rpmE2 NC_011601.1 282950 283213 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(282950..283213) Escherichia coli O127:H6 str. E2348/69 7062008 YP_002327836.1 CDS E2348C_0255 NC_011601.1 284152 285294 R NADH-dependent flavin oxidoreductase complement(284152..285294) Escherichia coli O127:H6 str. E2348/69 7062007 YP_002327837.1 CDS E2348C_0256 NC_011601.1 285466 286386 R hydrolases complement(285466..286386) Escherichia coli O127:H6 str. E2348/69 7063446 YP_002327838.1 CDS E2348C_0257 NC_011601.1 286543 287469 D transcriptional regulator 286543..287469 Escherichia coli O127:H6 str. E2348/69 7063447 YP_002327839.1 CDS E2348C_0258 NC_011601.1 287669 288562 D DNA-binding transcriptional regulator 287669..288562 Escherichia coli O127:H6 str. E2348/69 7063448 YP_002327840.1 CDS E2348C_0259 NC_011601.1 288593 289582 R aldo/keto reductase complement(288593..289582) Escherichia coli O127:H6 str. E2348/69 7063449 YP_002327841.1 CDS E2348C_0260 NC_011601.1 289609 290460 R aldo/keto reductases, related to diketogulonate reductase complement(289609..290460) Escherichia coli O127:H6 str. E2348/69 7063450 YP_002327842.1 CDS E2348C_0261 NC_011601.1 291026 295276 D adhesin/invasin 291026..295276 Escherichia coli O127:H6 str. E2348/69 7063451 YP_002327843.1 CDS ykgA NC_011601.1 295401 296258 R DNA-binding transcriptional regulator, AraC-type complement(295401..296258) Escherichia coli O127:H6 str. E2348/69 7063452 YP_002327844.1 CDS E2348C_0263 NC_011601.1 296506 297375 D reductase 296506..297375 Escherichia coli O127:H6 str. E2348/69 7061996 YP_002327845.1 CDS ykgB NC_011601.1 297535 298128 R hypothetical protein complement(297535..298128) Escherichia coli O127:H6 str. E2348/69 7063453 YP_002327846.1 CDS ykgI NC_011601.1 298140 298376 R hypothetical protein complement(298140..298376) Escherichia coli O127:H6 str. E2348/69 7061997 YP_002327847.1 CDS ykgC NC_011601.1 298485 299810 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(298485..299810) Escherichia coli O127:H6 str. E2348/69 7062004 YP_002327848.1 CDS ykgD NC_011601.1 300037 300891 D DNA-binding transcriptional regulator 300037..300891 Escherichia coli O127:H6 str. E2348/69 7061998 YP_002327849.1 CDS ykgE NC_011601.1 301419 302138 D oxidoreductase 301419..302138 Escherichia coli O127:H6 str. E2348/69 7061999 YP_002327850.1 CDS ykgF NC_011601.1 302149 303576 D amino acid dehydrogenase with NAD(P)-binding domain and ferridoxin-like domain 302149..303576 Escherichia coli O127:H6 str. E2348/69 7062000 YP_002327851.1 CDS ykgG NC_011601.1 303569 304264 D transporter 303569..304264 Escherichia coli O127:H6 str. E2348/69 7062001 YP_002327852.1 CDS E2348C_0271 NC_011601.1 304219 304431 R hypothetical protein complement(304219..304431) Escherichia coli O127:H6 str. E2348/69 7062002 YP_002327853.1 CDS betA NC_011601.1 305220 306890 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(305220..306890) Escherichia coli O127:H6 str. E2348/69 7062003 YP_002327854.1 CDS betB NC_011601.1 306904 308376 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(306904..308376) Escherichia coli O127:H6 str. E2348/69 7062506 YP_002327855.1 CDS betI NC_011601.1 308390 308977 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(308390..308977) Escherichia coli O127:H6 str. E2348/69 7062507 YP_002327856.1 CDS betT NC_011601.1 309106 311139 D proton-motive-force-driven choline transporter; choline transport protein BetT 309106..311139 Escherichia coli O127:H6 str. E2348/69 7062508 YP_002327857.1 CDS yahA NC_011601.1 312017 313105 D DNA-binding transcriptional regulator 312017..313105 Escherichia coli O127:H6 str. E2348/69 7062509 YP_002327858.1 CDS yahB NC_011601.1 313147 314079 R DNA-binding transcriptional regulator complement(313147..314079) Escherichia coli O127:H6 str. E2348/69 7064921 YP_002327859.1 CDS yahC NC_011601.1 314171 314668 R hypothetical protein complement(314171..314668) Escherichia coli O127:H6 str. E2348/69 7064922 YP_002327860.1 CDS yahD NC_011601.1 314926 315531 D transcriptional regulator with ankyrin domain 314926..315531 Escherichia coli O127:H6 str. E2348/69 7062705 YP_002327861.1 CDS yahE NC_011601.1 315571 316434 D hypothetical protein 315571..316434 Escherichia coli O127:H6 str. E2348/69 7062706 YP_002327862.1 CDS yahF NC_011601.1 316424 317971 D acyl-CoA synthetase with NAD(P)-binding domain and succinyl-CoA synthetase domain 316424..317971 Escherichia coli O127:H6 str. E2348/69 7063664 YP_002327863.1 CDS yahG NC_011601.1 317971 319389 D hypothetical protein 317971..319389 Escherichia coli O127:H6 str. E2348/69 7063669 YP_002327864.1 CDS yahH NC_011601.1 319415 319687 D hypothetical protein 319415..319687 Escherichia coli O127:H6 str. E2348/69 7063670 YP_002327865.1 CDS yahI NC_011601.1 319719 320669 D carbamate kinase 319719..320669 Escherichia coli O127:H6 str. E2348/69 7063671 YP_002327866.1 CDS yahJ NC_011601.1 320679 322061 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 320679..322061 Escherichia coli O127:H6 str. E2348/69 7063672 YP_002327867.1 CDS yahN NC_011601.1 324364 325038 R neutral amino-acid efflux system complement(324364..325038) Escherichia coli O127:H6 str. E2348/69 7063674 YP_002327868.1 CDS yahO NC_011601.1 325185 325460 D hypothetical protein 325185..325460 Escherichia coli O127:H6 str. E2348/69 7063675 YP_002327869.1 CDS prpR NC_011601.1 325561 327147 R DNA-binding transcriptional activator complement(325561..327147) Escherichia coli O127:H6 str. E2348/69 7063676 YP_002327870.1 CDS prpB NC_011601.1 327386 328267 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 327386..328267 Escherichia coli O127:H6 str. E2348/69 7061313 YP_002327871.1 CDS prpC NC_011601.1 328436 329605 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 328436..329605 Escherichia coli O127:H6 str. E2348/69 7061309 YP_002327872.1 CDS prpD NC_011601.1 329639 331090 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 329639..331090 Escherichia coli O127:H6 str. E2348/69 7061310 YP_002327873.1 CDS prpE NC_011601.1 331130 332941 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 331130..332941 Escherichia coli O127:H6 str. E2348/69 7061311 YP_002327874.1 CDS codB NC_011601.1 333266 334525 D cytosine permease 333266..334525 Escherichia coli O127:H6 str. E2348/69 7061312 YP_002327875.1 CDS codA NC_011601.1 334515 335798 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 334515..335798 Escherichia coli O127:H6 str. E2348/69 7062830 YP_002327876.1 CDS lacA NC_011601.1 335919 336530 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(335919..336530) Escherichia coli O127:H6 str. E2348/69 7062829 YP_002327877.1 CDS lacY NC_011601.1 336596 337849 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(336596..337849) Escherichia coli O127:H6 str. E2348/69 7061508 YP_002327878.1 CDS lacZ NC_011601.1 337901 340975 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(337901..340975) Escherichia coli O127:H6 str. E2348/69 7061510 YP_002327879.1 CDS lacI NC_011601.1 341098 342180 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(341098..342180) Escherichia coli O127:H6 str. E2348/69 7061511 YP_002327880.1 CDS yaiL NC_011601.1 342382 342921 D nucleoprotein/polynucleotide-associated enzyme 342382..342921 Escherichia coli O127:H6 str. E2348/69 7061509 YP_002327881.1 CDS frmB NC_011601.1 343047 343880 R esterase complement(343047..343880) Escherichia coli O127:H6 str. E2348/69 7063680 YP_002327882.1 CDS frmA NC_011601.1 343973 345082 R alcohol dehydrogenase complement(343973..345082) Escherichia coli O127:H6 str. E2348/69 7061955 YP_002327883.1 CDS frmR NC_011601.1 345117 345392 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(345117..345392) Escherichia coli O127:H6 str. E2348/69 7061954 YP_002327884.1 CDS tauA NC_011601.1 345698 346660 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 345698..346660 Escherichia coli O127:H6 str. E2348/69 7061956 YP_002327885.1 CDS tauB NC_011601.1 346673 347440 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 346673..347440 Escherichia coli O127:H6 str. E2348/69 7061760 YP_002327886.1 CDS tauC NC_011601.1 347437 348264 D taurine transporter subunit 347437..348264 Escherichia coli O127:H6 str. E2348/69 7061761 YP_002327887.1 CDS tauD NC_011601.1 348261 349112 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 348261..349112 Escherichia coli O127:H6 str. E2348/69 7061762 YP_002327888.1 CDS hemB NC_011601.1 349152 350126 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(349152..350126) Escherichia coli O127:H6 str. E2348/69 7061763 YP_002327889.1 CDS yaiV NC_011601.1 353654 354277 D DNA-binding transcriptional regulator 353654..354277 Escherichia coli O127:H6 str. E2348/69 7063681 YP_002327890.1 CDS ampH NC_011601.1 354278 355435 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(354278..355435) Escherichia coli O127:H6 str. E2348/69 7063682 YP_002327891.1 CDS sbmA NC_011601.1 355787 357007 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 355787..357007 Escherichia coli O127:H6 str. E2348/69 7061340 YP_002327892.1 CDS yaiY NC_011601.1 358181 358489 R hypothetical protein complement(358181..358489) Escherichia coli O127:H6 str. E2348/69 7063683 YP_002327893.1 CDS yaiZ NC_011601.1 358749 358961 D hypothetical protein 358749..358961 Escherichia coli O127:H6 str. E2348/69 7063684 YP_002327894.1 CDS ddl NC_011601.1 358985 360079 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(358985..360079) Escherichia coli O127:H6 str. E2348/69 7063685 YP_002327895.1 CDS iraP NC_011601.1 360542 360802 D hypothetical protein 360542..360802 Escherichia coli O127:H6 str. E2348/69 7065237 YP_002327896.1 CDS phoA NC_011601.1 360903 362318 D alkaline phosphatase 360903..362318 Escherichia coli O127:H6 str. E2348/69 7063545 YP_002327897.1 CDS psiF NC_011601.1 362437 362757 D hypothetical protein 362437..362757 Escherichia coli O127:H6 str. E2348/69 7060742 YP_002327898.1 CDS adrA NC_011601.1 362859 363974 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 362859..363974 Escherichia coli O127:H6 str. E2348/69 7061317 YP_002327899.1 CDS proC NC_011601.1 363991 364800 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(363991..364800) Escherichia coli O127:H6 str. E2348/69 7062412 YP_002327900.1 CDS yaiI NC_011601.1 364920 365378 D hypothetical protein 364920..365378 Escherichia coli O127:H6 str. E2348/69 7061298 YP_002327901.1 CDS aroL NC_011601.1 365561 366085 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 365561..366085 Escherichia coli O127:H6 str. E2348/69 7063679 YP_002327902.1 CDS yaiA NC_011601.1 366135 366326 D hypothetical protein 366135..366326 Escherichia coli O127:H6 str. E2348/69 7061398 YP_002327903.1 CDS aroM NC_011601.1 366584 367261 D hypothetical protein 366584..367261 Escherichia coli O127:H6 str. E2348/69 7063677 YP_002327904.1 CDS yaiE NC_011601.1 367333 367617 D hypothetical protein 367333..367617 Escherichia coli O127:H6 str. E2348/69 7061399 YP_002327905.1 CDS ykiA NC_011601.1 367825 368103 D hypothetical protein 367825..368103 Escherichia coli O127:H6 str. E2348/69 7063678 YP_002327906.1 CDS rdgC NC_011601.1 368261 369172 R Required for efficient pilin antigenic variation; recombination associated protein complement(368261..369172) Escherichia coli O127:H6 str. E2348/69 7062009 YP_002327907.1 CDS mak NC_011601.1 369297 370205 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 369297..370205 Escherichia coli O127:H6 str. E2348/69 7063969 YP_002327908.1 CDS araJ NC_011601.1 370343 371527 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(370343..371527) Escherichia coli O127:H6 str. E2348/69 7065269 YP_002327909.1 CDS sbcC NC_011601.1 371653 374796 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC complement(371653..374796) Escherichia coli O127:H6 str. E2348/69 7061362 YP_002327910.1 CDS sbcD NC_011601.1 374793 375995 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD complement(374793..375995) Escherichia coli O127:H6 str. E2348/69 7065333 YP_002327911.1 CDS phoB NC_011601.1 376185 376874 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 376185..376874 Escherichia coli O127:H6 str. E2348/69 7065334 YP_002327912.1 CDS phoR NC_011601.1 376932 378227 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 376932..378227 Escherichia coli O127:H6 str. E2348/69 7060743 YP_002327913.1 CDS brnQ NC_011601.1 378634 379953 D branched chain amino acid transporter (LIV-II) 378634..379953 Escherichia coli O127:H6 str. E2348/69 7060748 YP_002327914.1 CDS proY NC_011601.1 380029 381402 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; permease 380029..381402 Escherichia coli O127:H6 str. E2348/69 7062531 YP_002327915.1 CDS malZ NC_011601.1 381558 383375 D maltodextrin glucosidase 381558..383375 Escherichia coli O127:H6 str. E2348/69 7061308 YP_002327916.1 CDS acpH NC_011601.1 383380 383961 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase complement(383380..383961) Escherichia coli O127:H6 str. E2348/69 7065282 YP_002327917.1 CDS queA NC_011601.1 384180 385250 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 384180..385250 Escherichia coli O127:H6 str. E2348/69 7062392 YP_002327918.1 CDS tgt NC_011601.1 385305 386432 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 385305..386432 Escherichia coli O127:H6 str. E2348/69 7063943 YP_002327919.1 CDS yajC NC_011601.1 386455 386787 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 386455..386787 Escherichia coli O127:H6 str. E2348/69 7061779 YP_002327920.1 CDS secD NC_011601.1 386815 388662 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 386815..388662 Escherichia coli O127:H6 str. E2348/69 7063686 YP_002327921.1 CDS secF NC_011601.1 388673 389644 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 388673..389644 Escherichia coli O127:H6 str. E2348/69 7065354 YP_002327922.1 CDS yajD NC_011601.1 389773 390120 D hypothetical protein 389773..390120 Escherichia coli O127:H6 str. E2348/69 7065356 YP_002327923.1 CDS tsx NC_011601.1 390158 391042 R nucleoside channel phage T6/colicin K receptor complement(390158..391042) Escherichia coli O127:H6 str. E2348/69 7063687 YP_002327924.1 CDS yajI NC_011601.1 391341 391880 R hypothetical protein complement(391341..391880) Escherichia coli O127:H6 str. E2348/69 7062273 YP_002327925.1 CDS nrdR NC_011601.1 392031 392480 D transcriptional regulator NrdR 392031..392480 Escherichia coli O127:H6 str. E2348/69 7063689 YP_002327926.1 CDS ribD NC_011601.1 392484 393587 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 392484..393587 Escherichia coli O127:H6 str. E2348/69 7065417 YP_002327927.1 CDS ribH NC_011601.1 393676 394146 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 393676..394146 Escherichia coli O127:H6 str. E2348/69 7060821 YP_002327928.1 CDS nusB NC_011601.1 394166 394585 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 394166..394585 Escherichia coli O127:H6 str. E2348/69 7060822 YP_002327929.1 CDS thiL NC_011601.1 394663 395640 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 394663..395640 Escherichia coli O127:H6 str. E2348/69 7062869 YP_002327930.1 CDS pgpA NC_011601.1 395618 396136 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 395618..396136 Escherichia coli O127:H6 str. E2348/69 7061788 YP_002327931.1 CDS yajO NC_011601.1 396190 397164 R 2-carboxybenzaldehyde reductase complement(396190..397164) Escherichia coli O127:H6 str. E2348/69 7060717 YP_002327932.1 CDS dxs NC_011601.1 397219 399081 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(397219..399081) Escherichia coli O127:H6 str. E2348/69 7063691 YP_002327933.1 CDS ispA NC_011601.1 399106 400005 R geranyltranstransferase complement(399106..400005) Escherichia coli O127:H6 str. E2348/69 7065076 YP_002327934.1 CDS xseB NC_011601.1 400005 400247 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(400005..400247) Escherichia coli O127:H6 str. E2348/69 7063551 YP_002327935.1 CDS thiI NC_011601.1 400453 401901 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 400453..401901 Escherichia coli O127:H6 str. E2348/69 7064867 YP_002327936.1 CDS yajL NC_011601.1 401955 402545 R DJ-1 family protein complement(401955..402545) Escherichia coli O127:H6 str. E2348/69 7061786 YP_002327937.1 CDS panE NC_011601.1 402508 403419 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(402508..403419) Escherichia coli O127:H6 str. E2348/69 7063690 YP_002327938.1 CDS yajQ NC_011601.1 403587 404078 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 403587..404078 Escherichia coli O127:H6 str. E2348/69 7062909 YP_002327939.1 CDS yajR NC_011601.1 404206 405570 R transporter complement(404206..405570) Escherichia coli O127:H6 str. E2348/69 7063692 YP_002327940.1 CDS cyoE NC_011601.1 405719 406609 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(405719..406609) Escherichia coli O127:H6 str. E2348/69 7063693 YP_002327941.1 CDS cyoD NC_011601.1 406621 406950 R cytochrome o ubiquinol oxidase subunit IV complement(406621..406950) Escherichia coli O127:H6 str. E2348/69 7065192 YP_002327942.1 CDS cyoC NC_011601.1 406950 407564 R cytochrome o ubiquinol oxidase subunit III complement(406950..407564) Escherichia coli O127:H6 str. E2348/69 7065191 YP_002327943.1 CDS cyoB NC_011601.1 407554 409545 R cytochrome o ubiquinol oxidase subunit I complement(407554..409545) Escherichia coli O127:H6 str. E2348/69 7065190 YP_002327944.1 CDS cyoA NC_011601.1 409567 410514 R cytochrome o ubiquinol oxidase subunit II complement(409567..410514) Escherichia coli O127:H6 str. E2348/69 7065189 YP_002327945.1 CDS ampG NC_011601.1 410974 412449 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(410974..412449) Escherichia coli O127:H6 str. E2348/69 7065188 YP_002327946.1 CDS yajG NC_011601.1 412493 413071 R hypothetical protein complement(412493..413071) Escherichia coli O127:H6 str. E2348/69 7062624 YP_002327947.1 CDS bolA NC_011601.1 413376 413693 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 413376..413693 Escherichia coli O127:H6 str. E2348/69 7063688 YP_002327948.1 CDS tig NC_011601.1 414037 415335 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 414037..415335 Escherichia coli O127:H6 str. E2348/69 7062530 YP_002327949.1 CDS clpP NC_011601.1 415581 416204 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 415581..416204 Escherichia coli O127:H6 str. E2348/69 7061803 YP_002327950.1 CDS clpX NC_011601.1 416330 417604 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 416330..417604 Escherichia coli O127:H6 str. E2348/69 7062810 YP_002327951.1 CDS lon NC_011601.1 417793 420147 D DNA-binding ATP-dependent protease La 417793..420147 Escherichia coli O127:H6 str. E2348/69 7062812 YP_002327952.1 CDS hupB NC_011601.1 420356 420628 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 420356..420628 Escherichia coli O127:H6 str. E2348/69 7061559 YP_002327953.1 CDS ppiD NC_011601.1 420820 422691 D peptidyl-prolyl cis-trans isomerase 420820..422691 Escherichia coli O127:H6 str. E2348/69 7062194 YP_002327954.1 CDS ybaV NC_011601.1 422842 423213 D hypothetical protein 422842..423213 Escherichia coli O127:H6 str. E2348/69 7061273 YP_002327955.1 CDS ybaW NC_011601.1 423319 423717 D hypothetical protein 423319..423717 Escherichia coli O127:H6 str. E2348/69 7063707 YP_002327956.1 CDS queC NC_011601.1 423769 424464 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(423769..424464) Escherichia coli O127:H6 str. E2348/69 7063708 YP_002327957.1 CDS ybaE NC_011601.1 424529 426229 R transporter subunit: periplasmic-binding component of ABC superfamily complement(424529..426229) Escherichia coli O127:H6 str. E2348/69 7063944 YP_002327958.1 CDS cof NC_011601.1 426329 427147 D thiamin pyrimidine pyrophosphate hydrolase 426329..427147 Escherichia coli O127:H6 str. E2348/69 7063696 YP_002327959.1 CDS ybaO NC_011601.1 427300 427758 D DNA-binding transcriptional regulator 427300..427758 Escherichia coli O127:H6 str. E2348/69 7062831 YP_002327960.1 CDS mdlA NC_011601.1 427788 429560 D multidrug transporter membrane\ATP-binding components 427788..429560 Escherichia coli O127:H6 str. E2348/69 7063702 YP_002327961.1 CDS mdlB NC_011601.1 429553 431334 D multidrug transporter membrane\ATP-binding components 429553..431334 Escherichia coli O127:H6 str. E2348/69 7065299 YP_002327962.1 CDS glnK NC_011601.1 431515 431853 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 431515..431853 Escherichia coli O127:H6 str. E2348/69 7065300 YP_002327963.1 CDS amtB NC_011601.1 431883 433169 D ammonium transporter 431883..433169 Escherichia coli O127:H6 str. E2348/69 7061682 YP_002327964.1 CDS tesB NC_011601.1 433218 434078 R acyl-CoA thioesterase complement(433218..434078) Escherichia coli O127:H6 str. E2348/69 7061341 YP_002327965.1 CDS ybaY NC_011601.1 434296 434868 D outer membrane lipoprotein 434296..434868 Escherichia coli O127:H6 str. E2348/69 7061777 YP_002327966.1 CDS E2348C_0389 NC_011601.1 435058 436431 D transposase of ISEc13 435058..436431 Escherichia coli O127:H6 str. E2348/69 7064964 YP_002327967.1 CDS ybaZ NC_011601.1 436457 436846 R methyltransferase complement(436457..436846) Escherichia coli O127:H6 str. E2348/69 7063455 YP_002327968.1 CDS ybaA NC_011601.1 437147 437500 D hypothetical protein 437147..437500 Escherichia coli O127:H6 str. E2348/69 7062108 YP_002327969.1 CDS ylaB NC_011601.1 437542 439092 R hypothetical protein complement(437542..439092) Escherichia coli O127:H6 str. E2348/69 7063694 YP_002327970.1 CDS ylaC NC_011601.1 439256 439726 R hypothetical protein complement(439256..439726) Escherichia coli O127:H6 str. E2348/69 7062010 YP_002327971.1 CDS hha NC_011601.1 440568 440786 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(440568..440786) Escherichia coli O127:H6 str. E2348/69 7065264 YP_002327972.1 CDS ybaJ NC_011601.1 440812 441186 R hypothetical protein complement(440812..441186) Escherichia coli O127:H6 str. E2348/69 7062060 YP_002327973.1 CDS acrB NC_011601.1 441731 444880 R multidrug efflux system protein complement(441731..444880) Escherichia coli O127:H6 str. E2348/69 7063697 YP_002327974.1 CDS acrA NC_011601.1 444903 446096 R multidrug efflux system complement(444903..446096) Escherichia coli O127:H6 str. E2348/69 7062397 YP_002327975.1 CDS acrR NC_011601.1 446238 446885 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 446238..446885 Escherichia coli O127:H6 str. E2348/69 7062396 YP_002327976.1 CDS kefA NC_011601.1 447013 450375 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 447013..450375 Escherichia coli O127:H6 str. E2348/69 7062401 YP_002327977.1 CDS ybaM NC_011601.1 450587 450748 R hypothetical protein complement(450587..450748) Escherichia coli O127:H6 str. E2348/69 7063584 YP_002327978.1 CDS priC NC_011601.1 450762 451289 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(450762..451289) Escherichia coli O127:H6 str. E2348/69 7063700 YP_002327979.1 CDS ybaN NC_011601.1 451359 451736 D hypothetical protein 451359..451736 Escherichia coli O127:H6 str. E2348/69 7061290 YP_002327980.1 CDS apt NC_011601.1 451889 452440 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 451889..452440 Escherichia coli O127:H6 str. E2348/69 7063701 YP_002327981.1 CDS dnaX NC_011601.1 452569 454500 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 452569..454500 Escherichia coli O127:H6 str. E2348/69 7061354 YP_002327982.1 CDS ybaB NC_011601.1 454553 454882 D hypothetical protein 454553..454882 Escherichia coli O127:H6 str. E2348/69 7065054 YP_002327983.1 CDS recR NC_011601.1 454882 455487 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 454882..455487 Escherichia coli O127:H6 str. E2348/69 7063695 YP_002327984.1 CDS htpG NC_011601.1 455597 457471 D molecular chaperone; heat shock protein 90 455597..457471 Escherichia coli O127:H6 str. E2348/69 7063985 YP_002327985.1 CDS adk NC_011601.1 457652 458296 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 457652..458296 Escherichia coli O127:H6 str. E2348/69 7062189 YP_002327986.1 CDS hemH NC_011601.1 458428 459390 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 458428..459390 Escherichia coli O127:H6 str. E2348/69 7062411 YP_002327987.1 CDS aes NC_011601.1 459387 460346 R acetyl esterase complement(459387..460346) Escherichia coli O127:H6 str. E2348/69 7064298 YP_002327988.1 CDS gsk NC_011601.1 460498 461802 D inosine/guanosine kinase 460498..461802 Escherichia coli O127:H6 str. E2348/69 7062415 YP_002327989.1 CDS ybaL NC_011601.1 461932 463608 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(461932..463608) Escherichia coli O127:H6 str. E2348/69 7064256 YP_002327990.1 CDS fsr NC_011601.1 463847 465067 R fosmidomycin efflux system complement(463847..465067) Escherichia coli O127:H6 str. E2348/69 7063699 YP_002327991.1 CDS ushA NC_011601.1 465285 466937 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 465285..466937 Escherichia coli O127:H6 str. E2348/69 7061975 YP_002327992.1 CDS ybaK NC_011601.1 466974 467453 R hypothetical protein complement(466974..467453) Escherichia coli O127:H6 str. E2348/69 7062331 YP_002327993.1 CDS ybaP NC_011601.1 467656 468450 R hypothetical protein complement(467656..468450) Escherichia coli O127:H6 str. E2348/69 7062755 YP_002327994.1 CDS ybaQ NC_011601.1 468596 468937 D DNA-binding transcriptional regulator 468596..468937 Escherichia coli O127:H6 str. E2348/69 7063703 YP_002327995.1 CDS copA NC_011601.1 468995 471499 R copper exporting ATPase complement(468995..471499) Escherichia coli O127:H6 str. E2348/69 7063704 YP_002327996.1 CDS ybaS NC_011601.1 471762 472694 D catalyzes the formation of glutamate from glutamine; glutaminase 471762..472694 Escherichia coli O127:H6 str. E2348/69 7062832 YP_002327997.1 CDS ybaT NC_011601.1 472697 473989 D transporter 472697..473989 Escherichia coli O127:H6 str. E2348/69 7063705 YP_002327998.1 CDS cueR NC_011601.1 474114 474521 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 474114..474521 Escherichia coli O127:H6 str. E2348/69 7063706 YP_002327999.1 CDS E2348C_0424 NC_011601.1 475527 475949 R hypothetical protein complement(475527..475949) Escherichia coli O127:H6 str. E2348/69 7063456 YP_002328000.1 CDS E2348C_0425 NC_011601.1 476003 477019 R autotransporter adhesin, STEC autoagglutinating adhesin (Saa)-like protein complement(476003..477019) Escherichia coli O127:H6 str. E2348/69 7063457 YP_002328001.1 CDS E2348C_0426 NC_011601.1 477387 477749 D hypothetical protein 477387..477749 Escherichia coli O127:H6 str. E2348/69 7063458 YP_002328002.1 CDS ybbJ NC_011601.1 477852 478307 R hypothetical protein complement(477852..478307) Escherichia coli O127:H6 str. E2348/69 7063459 YP_002328003.1 CDS ybbK NC_011601.1 478307 479224 R protease, membrane anchored complement(478307..479224) Escherichia coli O127:H6 str. E2348/69 7063712 YP_002328004.1 CDS ybbL NC_011601.1 479370 480047 D ABC transporter ATP-binding protein 479370..480047 Escherichia coli O127:H6 str. E2348/69 7063713 YP_002328005.1 CDS ybbM NC_011601.1 480034 480813 D hypothetical protein 480034..480813 Escherichia coli O127:H6 str. E2348/69 7063714 YP_002328006.1 CDS ybbN NC_011601.1 480876 481730 R thioredoxin domain-containing protein complement(480876..481730) Escherichia coli O127:H6 str. E2348/69 7063715 YP_002328007.1 CDS ybbO NC_011601.1 481791 482600 R short chain dehydrogenase complement(481791..482600) Escherichia coli O127:H6 str. E2348/69 7063716 YP_002328008.1 CDS tesA NC_011601.1 482590 483216 R multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(482590..483216) Escherichia coli O127:H6 str. E2348/69 7063717 YP_002328009.1 CDS ybbA NC_011601.1 483184 483870 D ABC transporter ATP-binding protein 483184..483870 Escherichia coli O127:H6 str. E2348/69 7061776 YP_002328010.1 CDS ybbP NC_011601.1 483867 486281 D hypothetical protein 483867..486281 Escherichia coli O127:H6 str. E2348/69 7063710 YP_002328011.1 CDS E2348C_0436 NC_011601.1 486866 487912 D transposase 486866..487912 Escherichia coli O127:H6 str. E2348/69 7063718 YP_002328012.1 CDS ybbB NC_011601.1 488095 489189 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(488095..489189) Escherichia coli O127:H6 str. E2348/69 7063460 YP_002328013.1 CDS allS NC_011601.1 489258 490184 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(489258..490184) Escherichia coli O127:H6 str. E2348/69 7063711 YP_002328014.1 CDS allA NC_011601.1 490414 490896 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 490414..490896 Escherichia coli O127:H6 str. E2348/69 7062444 YP_002328015.1 CDS allR NC_011601.1 490974 491789 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 490974..491789 Escherichia coli O127:H6 str. E2348/69 7062439 YP_002328016.1 CDS gcl NC_011601.1 491879 493660 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 491879..493660 Escherichia coli O127:H6 str. E2348/69 7062443 YP_002328017.1 CDS hyi NC_011601.1 493673 494449 D hydroxypyruvate isomerase 493673..494449 Escherichia coli O127:H6 str. E2348/69 7061640 YP_002328018.1 CDS glxR NC_011601.1 494549 495427 D tartronate semialdehyde reductase, NADH-dependent 494549..495427 Escherichia coli O127:H6 str. E2348/69 7062218 YP_002328019.1 CDS ybbW NC_011601.1 495597 497051 D allantoin permease 495597..497051 Escherichia coli O127:H6 str. E2348/69 7061719 YP_002328020.1 CDS allB NC_011601.1 497111 498472 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 497111..498472 Escherichia coli O127:H6 str. E2348/69 7063719 YP_002328021.1 CDS ybbY NC_011601.1 498528 499829 D purine permease YbbY 498528..499829 Escherichia coli O127:H6 str. E2348/69 7062440 YP_002328022.1 CDS glxK NC_011601.1 499851 500996 D glycerate kinase 499851..500996 Escherichia coli O127:H6 str. E2348/69 7063720 YP_002328023.1 CDS ylbA NC_011601.1 501125 501910 R hypothetical protein complement(501125..501910) Escherichia coli O127:H6 str. E2348/69 7061718 YP_002328024.1 CDS allC NC_011601.1 501921 503156 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(501921..503156) Escherichia coli O127:H6 str. E2348/69 7062012 YP_002328025.1 CDS allD NC_011601.1 503178 504227 R ureidoglycolate dehydrogenase complement(503178..504227) Escherichia coli O127:H6 str. E2348/69 7062441 YP_002328026.1 CDS fdrA NC_011601.1 504544 506211 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 504544..506211 Escherichia coli O127:H6 str. E2348/69 7062442 YP_002328027.1 CDS ylbE NC_011601.1 506221 507480 D hypothetical protein 506221..507480 Escherichia coli O127:H6 str. E2348/69 7062094 YP_002328028.1 CDS ylbF NC_011601.1 507491 508306 D hypothetical protein 507491..508306 Escherichia coli O127:H6 str. E2348/69 7062013 YP_002328029.1 CDS ybcF NC_011601.1 508303 509196 D carbamate kinase 508303..509196 Escherichia coli O127:H6 str. E2348/69 7062014 YP_002328030.1 CDS purK NC_011601.1 509429 510496 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(509429..510496) Escherichia coli O127:H6 str. E2348/69 7063721 YP_002328031.1 CDS purE NC_011601.1 510493 511002 R N5-carboxyaminoimidazole ribonucleotide mutase complement(510493..511002) Escherichia coli O127:H6 str. E2348/69 7063918 YP_002328032.1 CDS lpxH NC_011601.1 511120 511842 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(511120..511842) Escherichia coli O127:H6 str. E2348/69 7063915 YP_002328033.1 CDS ppiB NC_011601.1 511845 512339 R peptidyl-prolyl cis-trans isomerase B complement(511845..512339) Escherichia coli O127:H6 str. E2348/69 7061576 YP_002328034.1 CDS cysS NC_011601.1 512513 513898 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 512513..513898 Escherichia coli O127:H6 str. E2348/69 7061271 YP_002328035.1 CDS ybcI NC_011601.1 513934 514455 R hypothetical protein complement(513934..514455) Escherichia coli O127:H6 str. E2348/69 7065206 YP_002328036.1 CDS ybcJ NC_011601.1 514563 514775 R hypothetical protein complement(514563..514775) Escherichia coli O127:H6 str. E2348/69 7063723 YP_002328037.1 CDS folD NC_011601.1 514777 515643 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(514777..515643) Escherichia coli O127:H6 str. E2348/69 7063724 YP_002328038.1 CDS E2348C_0465 NC_011601.1 517038 517694 R hypothetical protein complement(517038..517694) Escherichia coli O127:H6 str. E2348/69 7063462 YP_002328039.1 CDS ompT NC_011601.1 517938 518891 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(517938..518891) Escherichia coli O127:H6 str. E2348/69 7063463 YP_002328040.1 CDS ybcH NC_011601.1 519549 520439 R hypothetical protein complement(519549..520439) Escherichia coli O127:H6 str. E2348/69 7062879 YP_002328041.1 CDS nfrA NC_011601.1 520440 523412 R bacteriophage N4 receptor, outer membrane subunit complement(520440..523412) Escherichia coli O127:H6 str. E2348/69 7063722 YP_002328042.1 CDS nfrB NC_011601.1 523399 525636 R bacteriophage N4 adsorption protein B complement(523399..525636) Escherichia coli O127:H6 str. E2348/69 7065383 YP_002328043.1 CDS cusS NC_011601.1 525786 527228 R sensor kinase CusS complement(525786..527228) Escherichia coli O127:H6 str. E2348/69 7065384 YP_002328044.1 CDS cusR NC_011601.1 527218 527901 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(527218..527901) Escherichia coli O127:H6 str. E2348/69 7065174 YP_002328045.1 CDS cusC NC_011601.1 528058 529440 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 528058..529440 Escherichia coli O127:H6 str. E2348/69 7065173 YP_002328046.1 CDS cusF NC_011601.1 529464 529796 D copper-binding protein 529464..529796 Escherichia coli O127:H6 str. E2348/69 7065171 YP_002328047.1 CDS cusB NC_011601.1 529812 531035 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 529812..531035 Escherichia coli O127:H6 str. E2348/69 7065172 YP_002328048.1 CDS cusA NC_011601.1 531047 534190 D copper/silver efflux system, membrane component 531047..534190 Escherichia coli O127:H6 str. E2348/69 7065170 YP_002328049.1 CDS pheP NC_011601.1 534292 535674 D phenylalanine transporter 534292..535674 Escherichia coli O127:H6 str. E2348/69 7065169 YP_002328050.1 CDS ybdG NC_011601.1 535832 537079 R mechanosensitive channel complement(535832..537079) Escherichia coli O127:H6 str. E2348/69 7060723 YP_002328051.1 CDS nfsB NC_011601.1 537187 537840 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(537187..537840) Escherichia coli O127:H6 str. E2348/69 7063728 YP_002328052.1 CDS ybdF NC_011601.1 537919 538302 R hypothetical protein complement(537919..538302) Escherichia coli O127:H6 str. E2348/69 7065386 YP_002328053.1 CDS ybdJ NC_011601.1 538367 538615 R hypothetical protein complement(538367..538615) Escherichia coli O127:H6 str. E2348/69 7063727 YP_002328054.1 CDS ybdK NC_011601.1 538681 539799 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(538681..539799) Escherichia coli O127:H6 str. E2348/69 7063730 YP_002328055.1 CDS mokC2 NC_011601.1 540153 540404 D regulatory protein MokC for HokC 2 540153..540404 Escherichia coli O127:H6 str. E2348/69 7063731 YP_002328056.1 CDS hokC2 NC_011601.1 540252 540404 D small toxic membrane peptide HokC 2 540252..540404 Escherichia coli O127:H6 str. E2348/69 7063820 YP_002328057.1 CDS entD NC_011601.1 540526 541155 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(540526..541155) Escherichia coli O127:H6 str. E2348/69 7062170 YP_002328058.1 CDS fepA NC_011601.1 541321 543561 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(541321..543561) Escherichia coli O127:H6 str. E2348/69 7063855 YP_002328059.1 CDS fes NC_011601.1 543882 545006 D enterobactin/ferric enterobactin esterase 543882..545006 Escherichia coli O127:H6 str. E2348/69 7062100 YP_002328060.1 CDS ybdZ NC_011601.1 545009 545227 D hypothetical protein 545009..545227 Escherichia coli O127:H6 str. E2348/69 7062106 YP_002328061.1 CDS entF NC_011601.1 545224 549105 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 545224..549105 Escherichia coli O127:H6 str. E2348/69 7063736 YP_002328062.1 CDS fepC NC_011601.1 550451 551266 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(550451..551266) Escherichia coli O127:H6 str. E2348/69 7062104 YP_002328063.1 CDS fepG NC_011601.1 551263 552255 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(551263..552255) Escherichia coli O127:H6 str. E2348/69 7062102 YP_002328064.1 CDS fepD NC_011601.1 552252 553256 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(552252..553256) Escherichia coli O127:H6 str. E2348/69 7062105 YP_002328065.1 CDS entS NC_011601.1 553367 554617 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 553367..554617 Escherichia coli O127:H6 str. E2348/69 7062103 YP_002328066.1 CDS fepB NC_011601.1 554621 555577 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(554621..555577) Escherichia coli O127:H6 str. E2348/69 7063858 YP_002328067.1 CDS entC NC_011601.1 555766 556941 D isochorismate synthase 1 555766..556941 Escherichia coli O127:H6 str. E2348/69 7062101 YP_002328068.1 CDS entE NC_011601.1 556951 558561 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 556951..558561 Escherichia coli O127:H6 str. E2348/69 7063854 YP_002328069.1 CDS entB NC_011601.1 558575 559432 D isochorismatase 558575..559432 Escherichia coli O127:H6 str. E2348/69 7063856 YP_002328070.1 CDS entA NC_011601.1 559432 560178 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 559432..560178 Escherichia coli O127:H6 str. E2348/69 7063853 YP_002328071.1 CDS ybdB NC_011601.1 560181 560594 D hypothetical protein 560181..560594 Escherichia coli O127:H6 str. E2348/69 7063852 YP_002328072.1 CDS cstA NC_011601.1 560775 562880 D carbon starvation protein 560775..562880 Escherichia coli O127:H6 str. E2348/69 7063725 YP_002328073.1 CDS ybdD NC_011601.1 562993 563190 D hypothetical protein 562993..563190 Escherichia coli O127:H6 str. E2348/69 7065166 YP_002328074.1 CDS ybdH NC_011601.1 563200 564288 R member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein complement(563200..564288) Escherichia coli O127:H6 str. E2348/69 7063726 YP_002328075.1 CDS ybdL NC_011601.1 564397 565557 D catalyzes the transfer of an amino moiety; aminotransferase 564397..565557 Escherichia coli O127:H6 str. E2348/69 7063729 YP_002328076.1 CDS ybdM NC_011601.1 565558 566187 R hypothetical protein complement(565558..566187) Escherichia coli O127:H6 str. E2348/69 7063732 YP_002328077.1 CDS ybdN NC_011601.1 566160 567380 R hypothetical protein complement(566160..567380) Escherichia coli O127:H6 str. E2348/69 7063733 YP_002328078.1 CDS ybdO NC_011601.1 567527 568429 R DNA-binding transcriptional regulator complement(567527..568429) Escherichia coli O127:H6 str. E2348/69 7063734 YP_002328079.1 CDS dsbG NC_011601.1 568634 569380 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(568634..569380) Escherichia coli O127:H6 str. E2348/69 7063735 YP_002328080.1 CDS ahpC NC_011601.1 569752 570315 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 569752..570315 Escherichia coli O127:H6 str. E2348/69 7065065 YP_002328081.1 CDS ahpF NC_011601.1 570486 572051 D alkyl hydroperoxide reductase 570486..572051 Escherichia coli O127:H6 str. E2348/69 7062425 YP_002328082.1 CDS uspG NC_011601.1 572172 572600 R universal stress protein UP12 complement(572172..572600) Escherichia coli O127:H6 str. E2348/69 7062426 YP_002328083.1 CDS rnk NC_011601.1 572954 573364 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(572954..573364) Escherichia coli O127:H6 str. E2348/69 7062338 YP_002328084.1 CDS rna NC_011601.1 573594 574400 R ribonuclease I complement(573594..574400) Escherichia coli O127:H6 str. E2348/69 7060855 YP_002328085.1 CDS citT NC_011601.1 574514 575977 R citrate: succinate antiporter complement(574514..575977) Escherichia coli O127:H6 str. E2348/69 7060846 YP_002328086.1 CDS citG NC_011601.1 576028 576906 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(576028..576906) Escherichia coli O127:H6 str. E2348/69 7062804 YP_002328087.1 CDS citX NC_011601.1 576881 577432 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(576881..577432) Escherichia coli O127:H6 str. E2348/69 7062803 YP_002328088.1 CDS citF NC_011601.1 577436 578968 R citrate lyase, citrate-ACP transferase (alpha) subunit complement(577436..578968) Escherichia coli O127:H6 str. E2348/69 7062805 YP_002328089.1 CDS citE NC_011601.1 578979 579887 R citrate lyase, citryl-ACP lyase (beta) subunit complement(578979..579887) Escherichia coli O127:H6 str. E2348/69 7062802 YP_002328090.1 CDS citD NC_011601.1 579884 580180 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(579884..580180) Escherichia coli O127:H6 str. E2348/69 7062801 YP_002328091.1 CDS citC NC_011601.1 580195 581253 R citrate lyase synthetase complement(580195..581253) Escherichia coli O127:H6 str. E2348/69 7062800 YP_002328092.1 CDS citA NC_011601.1 581633 583291 D sensory histidine kinase CitA in two-component regulatory system with CitB 581633..583291 Escherichia coli O127:H6 str. E2348/69 7062799 YP_002328093.1 CDS dpiA NC_011601.1 583260 583940 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 583260..583940 Escherichia coli O127:H6 str. E2348/69 7062797 YP_002328094.1 CDS dcuC NC_011601.1 583981 585366 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(583981..585366) Escherichia coli O127:H6 str. E2348/69 7062798 YP_002328095.1 CDS pagP NC_011601.1 585943 586503 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 585943..586503 Escherichia coli O127:H6 str. E2348/69 7065233 YP_002328096.1 CDS cspE NC_011601.1 586678 586887 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 586678..586887 Escherichia coli O127:H6 str. E2348/69 7062904 YP_002328097.1 CDS crcB NC_011601.1 586941 587324 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(586941..587324) Escherichia coli O127:H6 str. E2348/69 7062863 YP_002328098.1 CDS ybeM NC_011601.1 587417 588205 D amidase 587417..588205 Escherichia coli O127:H6 str. E2348/69 7062841 YP_002328099.1 CDS tatE NC_011601.1 588334 588537 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 588334..588537 Escherichia coli O127:H6 str. E2348/69 7063742 YP_002328100.1 CDS lipA NC_011601.1 588637 589602 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(588637..589602) Escherichia coli O127:H6 str. E2348/69 7061759 YP_002328101.1 CDS lipB NC_011601.1 590423 591064 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(590423..591064) Escherichia coli O127:H6 str. E2348/69 7063740 YP_002328102.1 CDS ybeD NC_011601.1 591165 591428 R hypothetical protein complement(591165..591428) Escherichia coli O127:H6 str. E2348/69 7061543 YP_002328103.1 CDS dacA NC_011601.1 591538 592749 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(591538..592749) Escherichia coli O127:H6 str. E2348/69 7063739 YP_002328104.1 CDS rlpA NC_011601.1 592889 593977 R rare lipoprotein A complement(592889..593977) Escherichia coli O127:H6 str. E2348/69 7065212 YP_002328105.1 CDS mrdB NC_011601.1 593988 595100 R cell wall shape-determining protein complement(593988..595100) Escherichia coli O127:H6 str. E2348/69 7060836 YP_002328106.1 CDS mrdA NC_011601.1 595103 597004 R penicillin-binding protein 2 complement(595103..597004) Escherichia coli O127:H6 str. E2348/69 7060866 YP_002328107.1 CDS ybeA NC_011601.1 597035 597502 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(597035..597502) Escherichia coli O127:H6 str. E2348/69 7060865 YP_002328108.1 CDS ybeB NC_011601.1 597506 597823 R hypothetical protein complement(597506..597823) Escherichia coli O127:H6 str. E2348/69 7063737 YP_002328109.1 CDS cobC NC_011601.1 598083 598694 R alpha-ribazole-5'-phosphate phosphatase complement(598083..598694) Escherichia coli O127:H6 str. E2348/69 7063738 YP_002328110.1 CDS nadD NC_011601.1 598718 599359 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(598718..599359) Escherichia coli O127:H6 str. E2348/69 7062825 YP_002328111.1 CDS holA NC_011601.1 599361 600392 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(599361..600392) Escherichia coli O127:H6 str. E2348/69 7060907 YP_002328112.1 CDS rlpB NC_011601.1 600392 600973 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(600392..600973) Escherichia coli O127:H6 str. E2348/69 7062171 YP_002328113.1 CDS leuS NC_011601.1 600988 603570 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(600988..603570) Escherichia coli O127:H6 str. E2348/69 7060837 YP_002328114.1 CDS ybeL NC_011601.1 603805 604287 D hypothetical protein 603805..604287 Escherichia coli O127:H6 str. E2348/69 7061530 YP_002328115.1 CDS rihA NC_011601.1 604332 605267 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(604332..605267) Escherichia coli O127:H6 str. E2348/69 7063741 YP_002328116.1 CDS gltL NC_011601.1 605385 606110 R glutamate and aspartate transporter subunit complement(605385..606110) Escherichia coli O127:H6 str. E2348/69 7060824 YP_002328117.1 CDS gltK NC_011601.1 606110 606784 R glutamate/aspartate transport system permease GltK; membrane component of ABC superfamily complement(606110..606784) Escherichia coli O127:H6 str. E2348/69 7061710 YP_002328118.1 CDS gltJ NC_011601.1 606784 607524 R glutamate/aspartate transport system permease GltJ; membrane component of ABC superfamily complement(606784..607524) Escherichia coli O127:H6 str. E2348/69 7061709 YP_002328119.1 CDS gltI NC_011601.1 607694 608602 R glutamate and aspartate transporter subunit complement(607694..608602) Escherichia coli O127:H6 str. E2348/69 7062756 YP_002328120.1 CDS E2348C_0549 NC_011601.1 609056 610933 D hypothetical protein 609056..610933 Escherichia coli O127:H6 str. E2348/69 7061707 YP_002328121.1 CDS lnt NC_011601.1 611066 612607 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(611066..612607) Escherichia coli O127:H6 str. E2348/69 7063464 YP_002328122.1 CDS ybeX NC_011601.1 612632 613510 R ion transport complement(612632..613510) Escherichia coli O127:H6 str. E2348/69 7061553 YP_002328123.1 CDS ybeY NC_011601.1 613600 614067 R metalloprotease complement(613600..614067) Escherichia coli O127:H6 str. E2348/69 7063743 YP_002328124.1 CDS ybeZ NC_011601.1 614064 615143 R hypothetical protein complement(614064..615143) Escherichia coli O127:H6 str. E2348/69 7063744 YP_002328125.1 CDS miaB NC_011601.1 615257 616681 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(615257..616681) Escherichia coli O127:H6 str. E2348/69 7063745 YP_002328126.1 CDS ubiF NC_011601.1 616827 618002 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 616827..618002 Escherichia coli O127:H6 str. E2348/69 7063784 YP_002328127.1 CDS asnB NC_011601.1 619130 620794 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(619130..620794) Escherichia coli O127:H6 str. E2348/69 7063770 YP_002328128.1 CDS nagD NC_011601.1 621051 621803 R UMP phosphatase complement(621051..621803) Escherichia coli O127:H6 str. E2348/69 7061412 YP_002328129.1 CDS nagC NC_011601.1 621851 623071 R DNA-binding transcriptional dual regulator, repressor of the N-acetylglucosamine operon complement(621851..623071) Escherichia coli O127:H6 str. E2348/69 7060914 YP_002328130.1 CDS nagA NC_011601.1 623080 624228 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(623080..624228) Escherichia coli O127:H6 str. E2348/69 7060913 YP_002328131.1 CDS nagB NC_011601.1 624288 625088 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(624288..625088) Escherichia coli O127:H6 str. E2348/69 7060911 YP_002328132.1 CDS nagE NC_011601.1 625421 627367 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 625421..627367 Escherichia coli O127:H6 str. E2348/69 7060912 YP_002328133.1 CDS E2348C_0562 NC_011601.1 627456 628736 R hypothetical protein complement(627456..628736) Escherichia coli O127:H6 str. E2348/69 7060915 YP_002328134.1 CDS E2348C_0563 NC_011601.1 628750 629220 R hypothetical protein complement(628750..629220) Escherichia coli O127:H6 str. E2348/69 7063465 YP_002328135.1 CDS E2348C_0564 NC_011601.1 629217 630386 R hypothetical protein complement(629217..630386) Escherichia coli O127:H6 str. E2348/69 7063466 YP_002328136.1 CDS E2348C_0565 NC_011601.1 630422 631180 R TerC family integral membrane protein complement(630422..631180) Escherichia coli O127:H6 str. E2348/69 7063467 YP_002328137.1 CDS E2348C_0566 NC_011601.1 631240 632127 R dihydrodipicolinate synthase complement(631240..632127) Escherichia coli O127:H6 str. E2348/69 7063468 YP_002328138.1 CDS E2348C_0567 NC_011601.1 632131 633288 R alcohol dehydrogenase complement(632131..633288) Escherichia coli O127:H6 str. E2348/69 7063469 YP_002328139.1 CDS E2348C_0568 NC_011601.1 633458 634693 D hypothetical protein 633458..634693 Escherichia coli O127:H6 str. E2348/69 7063470 YP_002328140.1 CDS pdxA NC_011601.1 634686 635672 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 634686..635672 Escherichia coli O127:H6 str. E2348/69 7063471 YP_002328141.1 CDS E2348C_0570 NC_011601.1 635674 636435 D DeoR family transcriptional regulator 635674..636435 Escherichia coli O127:H6 str. E2348/69 7063472 YP_002328142.1 CDS glnS NC_011601.1 636655 638319 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 636655..638319 Escherichia coli O127:H6 str. E2348/69 7063473 YP_002328143.1 CDS ybfM NC_011601.1 638761 640167 D outer membrane porin 638761..640167 Escherichia coli O127:H6 str. E2348/69 7061686 YP_002328144.1 CDS ybfN NC_011601.1 640217 640543 D lipoprotein 640217..640543 Escherichia coli O127:H6 str. E2348/69 7063264 YP_002328145.1 CDS fur NC_011601.1 640627 641073 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(640627..641073) Escherichia coli O127:H6 str. E2348/69 7063265 YP_002328146.1 CDS uof NC_011601.1 641066 641152 R ryhB-regulated fur leader peptide complement(641066..641152) Escherichia coli O127:H6 str. E2348/69 7061603 YP_002328147.1 CDS fldA NC_011601.1 641362 641892 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(641362..641892) Escherichia coli O127:H6 str. E2348/69 7062327 YP_002328148.1 CDS ybfE NC_011601.1 642032 642325 R LexA regulated protein complement(642032..642325) Escherichia coli O127:H6 str. E2348/69 7062136 YP_002328149.1 CDS ybfF NC_011601.1 642465 643229 R hypothetical protein complement(642465..643229) Escherichia coli O127:H6 str. E2348/69 7063747 YP_002328150.1 CDS seqA NC_011601.1 643414 643959 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 643414..643959 Escherichia coli O127:H6 str. E2348/69 7063183 YP_002328151.1 CDS pgm NC_011601.1 643985 645625 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 643985..645625 Escherichia coli O127:H6 str. E2348/69 7065365 YP_002328152.1 CDS potE NC_011601.1 645682 647001 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(645682..647001) Escherichia coli O127:H6 str. E2348/69 7060716 YP_002328153.1 CDS speF NC_011601.1 646998 649196 R ornithine decarboxylase complement(646998..649196) Escherichia coli O127:H6 str. E2348/69 7060774 YP_002328154.1 CDS kdpE NC_011601.1 649792 650469 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(649792..650469) Escherichia coli O127:H6 str. E2348/69 7062745 YP_002328155.1 CDS kdpD NC_011601.1 650466 653150 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(650466..653150) Escherichia coli O127:H6 str. E2348/69 7063576 YP_002328156.1 CDS kdpC NC_011601.1 653143 653715 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(653143..653715) Escherichia coli O127:H6 str. E2348/69 7063575 YP_002328157.1 CDS kdpB NC_011601.1 653724 655772 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(653724..655772) Escherichia coli O127:H6 str. E2348/69 7063574 YP_002328158.1 CDS kdpA NC_011601.1 655795 657468 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(655795..657468) Escherichia coli O127:H6 str. E2348/69 7063573 YP_002328159.1 CDS kdpF NC_011601.1 657468 657557 R one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit F complement(657468..657557) Escherichia coli O127:H6 str. E2348/69 7063572 YP_002328160.1 CDS ybfA NC_011601.1 657870 658076 D hypothetical protein 657870..658076 Escherichia coli O127:H6 str. E2348/69 7063577 YP_002328161.1 CDS ybgA NC_011601.1 658177 658686 D hypothetical protein 658177..658686 Escherichia coli O127:H6 str. E2348/69 7063746 YP_002328162.1 CDS phr NC_011601.1 658683 660101 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 658683..660101 Escherichia coli O127:H6 str. E2348/69 7063266 YP_002328163.1 CDS ybgH NC_011601.1 660143 661624 R transporter complement(660143..661624) Escherichia coli O127:H6 str. E2348/69 7060751 YP_002328164.1 CDS ybgI NC_011601.1 661895 662638 D hydrolase-oxidase 661895..662638 Escherichia coli O127:H6 str. E2348/69 7063270 YP_002328165.1 CDS ybgJ NC_011601.1 662661 663317 D carboxylase subunit 662661..663317 Escherichia coli O127:H6 str. E2348/69 7063271 YP_002328166.1 CDS ybgK NC_011601.1 663311 664243 D carboxylase subunit 663311..664243 Escherichia coli O127:H6 str. E2348/69 7063272 YP_002328167.1 CDS ybgL NC_011601.1 664233 664967 D LamB/YcsF family protein 664233..664967 Escherichia coli O127:H6 str. E2348/69 7063273 YP_002328168.1 CDS nei NC_011601.1 665003 665794 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 665003..665794 Escherichia coli O127:H6 str. E2348/69 7063274 YP_002328169.1 CDS abrB NC_011601.1 665791 666837 R regulator complement(665791..666837) Escherichia coli O127:H6 str. E2348/69 7065378 YP_002328170.1 CDS gltA NC_011601.1 667511 668794 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(667511..668794) Escherichia coli O127:H6 str. E2348/69 7063275 YP_002328171.1 CDS sdhC NC_011601.1 669503 669892 D succinate dehydrogenase cytochrome b556 large membrane subunit 669503..669892 Escherichia coli O127:H6 str. E2348/69 7061704 YP_002328172.1 CDS sdhD NC_011601.1 669886 670233 D succinate dehydrogenase cytochrome b556 small membrane subunit 669886..670233 Escherichia coli O127:H6 str. E2348/69 7065349 YP_002328173.1 CDS sdhA NC_011601.1 670233 671999 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 670233..671999 Escherichia coli O127:H6 str. E2348/69 7065350 YP_002328174.1 CDS sdhB NC_011601.1 672015 672731 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 672015..672731 Escherichia coli O127:H6 str. E2348/69 7065347 YP_002328175.1 CDS sucA NC_011601.1 673043 675844 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 673043..675844 Escherichia coli O127:H6 str. E2348/69 7065348 YP_002328176.1 CDS sucB NC_011601.1 675859 677076 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 675859..677076 Escherichia coli O127:H6 str. E2348/69 7062777 YP_002328177.1 CDS sucC NC_011601.1 677170 678336 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 677170..678336 Escherichia coli O127:H6 str. E2348/69 7062778 YP_002328178.1 CDS sucD NC_011601.1 678336 679205 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 678336..679205 Escherichia coli O127:H6 str. E2348/69 7062779 YP_002328179.1 CDS mngR NC_011601.1 679309 680031 R regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR complement(679309..680031) Escherichia coli O127:H6 str. E2348/69 7062780 YP_002328180.1 CDS E2348C_0611 NC_011601.1 680697 682070 D transposase of ISEc13 680697..682070 Escherichia coli O127:H6 str. E2348/69 7064965 YP_002328181.1 CDS E2348C_0612 NC_011601.1 682142 682591 R converts methylaspartate to L-glutamate; methylaspartate mutase subunit S complement(682142..682591) Escherichia coli O127:H6 str. E2348/69 7063474 YP_002328182.1 CDS E2348C_0613 NC_011601.1 682778 682945 R hypothetical protein complement(682778..682945) Escherichia coli O127:H6 str. E2348/69 7063475 YP_002328183.1 CDS E2348C_0614 NC_011601.1 683138 683560 R hypothetical protein complement(683138..683560) Escherichia coli O127:H6 str. E2348/69 7063476 YP_002328184.1 CDS E2348C_0615 NC_011601.1 683641 684585 R hypothetical protein complement(683641..684585) Escherichia coli O127:H6 str. E2348/69 7063477 YP_002328185.1 CDS cydA NC_011601.1 685391 686959 D cytochrome d terminal oxidase, subunit I 685391..686959 Escherichia coli O127:H6 str. E2348/69 7063478 YP_002328186.1 CDS cydB NC_011601.1 686975 688114 D cytochrome d terminal oxidase, subunit II 686975..688114 Escherichia coli O127:H6 str. E2348/69 7065184 YP_002328187.1 CDS ybgT NC_011601.1 688129 688242 D hypothetical protein 688129..688242 Escherichia coli O127:H6 str. E2348/69 7065185 YP_002328188.1 CDS ybgE NC_011601.1 688242 688535 D hypothetical protein 688242..688535 Escherichia coli O127:H6 str. E2348/69 7063277 YP_002328189.1 CDS ybgC NC_011601.1 688685 689089 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 688685..689089 Escherichia coli O127:H6 str. E2348/69 7063268 YP_002328190.1 CDS tolQ NC_011601.1 689086 689778 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 689086..689778 Escherichia coli O127:H6 str. E2348/69 7063267 YP_002328191.1 CDS tolR NC_011601.1 689782 690210 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 689782..690210 Escherichia coli O127:H6 str. E2348/69 7061815 YP_002328192.1 CDS tolA NC_011601.1 690275 691477 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 690275..691477 Escherichia coli O127:H6 str. E2348/69 7061816 YP_002328193.1 CDS tolB NC_011601.1 691610 692902 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 691610..692902 Escherichia coli O127:H6 str. E2348/69 7061812 YP_002328194.1 CDS pal NC_011601.1 692937 693458 D peptidoglycan-associated outer membrane lipoprotein 692937..693458 Escherichia coli O127:H6 str. E2348/69 7061813 YP_002328195.1 CDS ybgF NC_011601.1 693468 694259 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 693468..694259 Escherichia coli O127:H6 str. E2348/69 7062905 YP_002328196.1 CDS nadA NC_011601.1 695669 696712 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 695669..696712 Escherichia coli O127:H6 str. E2348/69 7065254 YP_002328197.1 CDS pnuC NC_011601.1 696750 697469 D nicotinamide mononucleotide transporter 696750..697469 Escherichia coli O127:H6 str. E2348/69 7060904 YP_002328198.1 CDS zitB NC_011601.1 697466 698407 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(697466..698407) Escherichia coli O127:H6 str. E2348/69 7060766 YP_002328199.1 CDS ybgS NC_011601.1 698521 698901 R hypothetical protein complement(698521..698901) Escherichia coli O127:H6 str. E2348/69 7063260 YP_002328200.1 CDS aroG NC_011601.1 699217 700269 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 699217..700269 Escherichia coli O127:H6 str. E2348/69 7063276 YP_002328201.1 CDS gpmA NC_011601.1 700435 701187 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(700435..701187) Escherichia coli O127:H6 str. E2348/69 7061395 YP_002328202.1 CDS galM NC_011601.1 701390 702430 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(701390..702430) Escherichia coli O127:H6 str. E2348/69 7064234 YP_002328203.1 CDS galK NC_011601.1 702424 703572 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(702424..703572) Escherichia coli O127:H6 str. E2348/69 7061619 YP_002328204.1 CDS galT NC_011601.1 703576 704622 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(703576..704622) Escherichia coli O127:H6 str. E2348/69 7061618 YP_002328205.1 CDS E2348C_0636 NC_011601.1 704632 705648 R UDP-galactose-4-epimerase complement(704632..705648) Escherichia coli O127:H6 str. E2348/69 7061623 YP_002328206.1 CDS modF NC_011601.1 705898 707370 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(705898..707370) Escherichia coli O127:H6 str. E2348/69 7063479 YP_002328207.1 CDS modE NC_011601.1 707438 708226 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(707438..708226) Escherichia coli O127:H6 str. E2348/69 7063816 YP_002328208.1 CDS ybhT NC_011601.1 708355 708504 D hypothetical protein 708355..708504 Escherichia coli O127:H6 str. E2348/69 7063815 YP_002328209.1 CDS modA NC_011601.1 708671 709444 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 708671..709444 Escherichia coli O127:H6 str. E2348/69 7063296 YP_002328210.1 CDS modB NC_011601.1 709444 710133 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 709444..710133 Escherichia coli O127:H6 str. E2348/69 7063812 YP_002328211.1 CDS modC NC_011601.1 710136 711194 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 710136..711194 Escherichia coli O127:H6 str. E2348/69 7063813 YP_002328212.1 CDS ybhA NC_011601.1 711195 712013 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(711195..712013) Escherichia coli O127:H6 str. E2348/69 7063814 YP_002328213.1 CDS pgl NC_011601.1 712168 713163 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 712168..713163 Escherichia coli O127:H6 str. E2348/69 7063278 YP_002328214.1 CDS ybhD NC_011601.1 713204 714157 R DNA-binding transcriptional regulator complement(713204..714157) Escherichia coli O127:H6 str. E2348/69 7060715 YP_002328215.1 CDS ybhH NC_011601.1 714341 715393 D hypothetical protein 714341..715393 Escherichia coli O127:H6 str. E2348/69 7063281 YP_002328216.1 CDS ybhI NC_011601.1 715469 716812 D transporter 715469..716812 Escherichia coli O127:H6 str. E2348/69 7063284 YP_002328217.1 CDS ybhJ NC_011601.1 717072 719333 D hypothetical protein 717072..719333 Escherichia coli O127:H6 str. E2348/69 7063285 YP_002328218.1 CDS ybhC NC_011601.1 719473 720756 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase complement(719473..720756) Escherichia coli O127:H6 str. E2348/69 7063286 YP_002328219.1 CDS E2348C_0650 NC_011601.1 720891 721961 R integrase complement(720891..721961) Escherichia coli O127:H6 str. E2348/69 7061166 YP_002328220.1 CDS E2348C_0651 NC_011601.1 721939 722157 R excisionase complement(721939..722157) Escherichia coli O127:H6 str. E2348/69 7063480 YP_002328221.1 CDS E2348C_0652 NC_011601.1 722197 722364 R hypothetical protein complement(722197..722364) Escherichia coli O127:H6 str. E2348/69 7063481 YP_002328222.1 CDS E2348C_0653 NC_011601.1 722437 722721 R hypothetical protein complement(722437..722721) Escherichia coli O127:H6 str. E2348/69 7063482 YP_002328223.1 CDS E2348C_0654 NC_011601.1 722714 723346 R hypothetical protein complement(722714..723346) Escherichia coli O127:H6 str. E2348/69 7063483 YP_002328224.1 CDS E2348C_0655 NC_011601.1 723357 723554 R hypothetical protein complement(723357..723554) Escherichia coli O127:H6 str. E2348/69 7063484 YP_002328225.1 CDS E2348C_0656 NC_011601.1 723556 723951 R hypothetical protein complement(723556..723951) Escherichia coli O127:H6 str. E2348/69 7063485 YP_002328226.1 CDS E2348C_0657 NC_011601.1 723970 724101 R hypothetical protein complement(723970..724101) Escherichia coli O127:H6 str. E2348/69 7063486 YP_002328227.1 CDS E2348C_0658 NC_011601.1 724147 724785 R hypothetical protein complement(724147..724785) Escherichia coli O127:H6 str. E2348/69 7063487 YP_002328228.1 CDS E2348C_0659 NC_011601.1 724772 725041 R hypothetical protein complement(724772..725041) Escherichia coli O127:H6 str. E2348/69 7063488 YP_002328229.1 CDS E2348C_0660 NC_011601.1 725038 725205 R hypothetical protein complement(725038..725205) Escherichia coli O127:H6 str. E2348/69 7063489 YP_002328230.1 CDS E2348C_0661 NC_011601.1 725216 725512 R anti-RecBCD protein complement(725216..725512) Escherichia coli O127:H6 str. E2348/69 7063490 YP_002328231.1 CDS E2348C_0662 NC_011601.1 725526 726032 R single-stranded DNA-binding protein complement(725526..726032) Escherichia coli O127:H6 str. E2348/69 7063491 YP_002328232.1 CDS E2348C_0663 NC_011601.1 726029 726496 R hypothetical protein complement(726029..726496) Escherichia coli O127:H6 str. E2348/69 7063492 YP_002328233.1 CDS E2348C_0664 NC_011601.1 726497 727204 R recombination protein complement(726497..727204) Escherichia coli O127:H6 str. E2348/69 7063493 YP_002328234.1 CDS E2348C_0665 NC_011601.1 727213 727383 R hypothetical protein complement(727213..727383) Escherichia coli O127:H6 str. E2348/69 7063494 YP_002328235.1 CDS E2348C_0666 NC_011601.1 727459 727704 R hypothetical protein complement(727459..727704) Escherichia coli O127:H6 str. E2348/69 7063495 YP_002328236.1 CDS E2348C_0667 NC_011601.1 727705 728073 R single-stranded DNA-binding protein complement(727705..728073) Escherichia coli O127:H6 str. E2348/69 7063496 YP_002328237.1 CDS E2348C_0668 NC_011601.1 728253 728576 R hypothetical protein complement(728253..728576) Escherichia coli O127:H6 str. E2348/69 7063497 YP_002328238.1 CDS E2348C_0669 NC_011601.1 728639 728863 R hypothetical protein complement(728639..728863) Escherichia coli O127:H6 str. E2348/69 7063498 YP_002328239.1 CDS E2348C_0670 NC_011601.1 728867 729175 R early gene regulator complement(728867..729175) Escherichia coli O127:H6 str. E2348/69 7063499 YP_002328240.1 CDS E2348C_0671 NC_011601.1 729618 730442 R hypothetical protein complement(729618..730442) Escherichia coli O127:H6 str. E2348/69 7063500 YP_002328241.1 CDS E2348C_0672 NC_011601.1 730647 731354 R repressor protein complement(730647..731354) Escherichia coli O127:H6 str. E2348/69 7063501 YP_002328242.1 CDS E2348C_0673 NC_011601.1 731433 731660 D antirepressor protein 731433..731660 Escherichia coli O127:H6 str. E2348/69 7063502 YP_002328243.1 CDS E2348C_0674 NC_011601.1 731767 732066 D regulatory protein 731767..732066 Escherichia coli O127:H6 str. E2348/69 7063503 YP_002328244.1 CDS E2348C_0675 NC_011601.1 732229 733005 D replication protein 732229..733005 Escherichia coli O127:H6 str. E2348/69 7063505 YP_002328245.1 CDS E2348C_0676 NC_011601.1 733113 734993 D replication protein 733113..734993 Escherichia coli O127:H6 str. E2348/69 7063585 YP_002328246.1 CDS E2348C_0677 NC_011601.1 735071 735511 D protein NinB 735071..735511 Escherichia coli O127:H6 str. E2348/69 7063586 YP_002328247.1 CDS E2348C_0678 NC_011601.1 735508 735690 D protein NinE 735508..735690 Escherichia coli O127:H6 str. E2348/69 7063587 YP_002328248.1 CDS E2348C_0679 NC_011601.1 735687 735866 D protein NinF 735687..735866 Escherichia coli O127:H6 str. E2348/69 7063588 YP_002328249.1 CDS E2348C_0680 NC_011601.1 735907 736335 D endonuclease 735907..736335 Escherichia coli O127:H6 str. E2348/69 7063589 YP_002328250.1 CDS E2348C_0681 NC_011601.1 736389 736781 D hypothetical protein 736389..736781 Escherichia coli O127:H6 str. E2348/69 7063590 YP_002328251.1 CDS E2348C_0682 NC_011601.1 736774 737064 D hypothetical protein 736774..737064 Escherichia coli O127:H6 str. E2348/69 7063591 YP_002328252.1 CDS E2348C_0683 NC_011601.1 737195 737554 R hypothetical protein complement(737195..737554) Escherichia coli O127:H6 str. E2348/69 7063592 YP_002328253.1 CDS E2348C_0684 NC_011601.1 737820 738779 R SfpA (systemic factor protein A)-like protein complement(737820..738779) Escherichia coli O127:H6 str. E2348/69 7063593 YP_002328254.1 CDS E2348C_0685 NC_011601.1 739255 739944 D late gene regulator 739255..739944 Escherichia coli O127:H6 str. E2348/69 7063594 YP_002328255.1 CDS E2348C_0686 NC_011601.1 740156 740872 D membrane protein 740156..740872 Escherichia coli O127:H6 str. E2348/69 7063595 YP_002328256.1 CDS E2348C_0687 NC_011601.1 740958 741116 D hypothetical protein 740958..741116 Escherichia coli O127:H6 str. E2348/69 7063596 YP_002328257.1 CDS E2348C_0688 NC_011601.1 741415 743265 D hypothetical protein 741415..743265 Escherichia coli O127:H6 str. E2348/69 7063597 YP_002328258.1 CDS E2348C_0689 NC_011601.1 743713 743919 D holin protein 743713..743919 Escherichia coli O127:H6 str. E2348/69 7063598 YP_002328259.1 CDS E2348C_0690 NC_011601.1 743919 744416 D endolysin 743919..744416 Escherichia coli O127:H6 str. E2348/69 7063599 YP_002328260.1 CDS E2348C_0691 NC_011601.1 744413 744850 D endopeptidase 744413..744850 Escherichia coli O127:H6 str. E2348/69 7063600 YP_002328261.1 CDS E2348C_0692 NC_011601.1 744612 744797 D lipoprotein Rz1 744612..744797 Escherichia coli O127:H6 str. E2348/69 7063601 YP_002328262.1 CDS E2348C_0693 NC_011601.1 745000 745617 D hypothetical protein 745000..745617 Escherichia coli O127:H6 str. E2348/69 7063602 YP_002328263.1 CDS E2348C_0694 NC_011601.1 745805 745999 R hypothetical protein complement(745805..745999) Escherichia coli O127:H6 str. E2348/69 7063603 YP_002328264.1 CDS E2348C_0695 NC_011601.1 746394 746903 D terminase small subunit 746394..746903 Escherichia coli O127:H6 str. E2348/69 7063604 YP_002328265.1 CDS E2348C_0696 NC_011601.1 746875 748803 D terminase large subunit 746875..748803 Escherichia coli O127:H6 str. E2348/69 7063605 YP_002328266.1 CDS E2348C_0697 NC_011601.1 748787 748993 D head-tail joining protein 748787..748993 Escherichia coli O127:H6 str. E2348/69 7063606 YP_002328267.1 CDS E2348C_0698 NC_011601.1 748990 750582 D portal protein 748990..750582 Escherichia coli O127:H6 str. E2348/69 7063607 YP_002328268.1 CDS E2348C_0699 NC_011601.1 750572 752077 D head protein/prohead protease 750572..752077 Escherichia coli O127:H6 str. E2348/69 7063608 YP_002328269.1 CDS E2348C_0700 NC_011601.1 752114 752461 D head-DNA stabilization protein 752114..752461 Escherichia coli O127:H6 str. E2348/69 7063609 YP_002328270.1 CDS E2348C_0701 NC_011601.1 752519 753547 D major capsid protein 752519..753547 Escherichia coli O127:H6 str. E2348/69 7063610 YP_002328271.1 CDS E2348C_0702 NC_011601.1 753599 753973 D DNA packaging protein 753599..753973 Escherichia coli O127:H6 str. E2348/69 7063611 YP_002328272.1 CDS E2348C_0703 NC_011601.1 753966 754319 D head-tail adapotor 753966..754319 Escherichia coli O127:H6 str. E2348/69 7063612 YP_002328273.1 CDS E2348C_0704 NC_011601.1 754334 754867 D minor tail protein 754334..754867 Escherichia coli O127:H6 str. E2348/69 7063613 YP_002328274.1 CDS E2348C_0705 NC_011601.1 754864 755259 D minor tail protein 754864..755259 Escherichia coli O127:H6 str. E2348/69 7063614 YP_002328275.1 CDS E2348C_0706 NC_011601.1 755267 756019 D major tail protein 755267..756019 Escherichia coli O127:H6 str. E2348/69 7063615 YP_002328276.1 CDS E2348C_0707 NC_011601.1 756033 756464 D minor tail protein 756033..756464 Escherichia coli O127:H6 str. E2348/69 7063616 YP_002328277.1 CDS E2348C_0708 NC_011601.1 756491 756904 D minor tail protein 756491..756904 Escherichia coli O127:H6 str. E2348/69 7063617 YP_002328278.1 CDS E2348C_0709 NC_011601.1 756885 759446 D tail length tape measure protein 756885..759446 Escherichia coli O127:H6 str. E2348/69 7063618 YP_002328279.1 CDS E2348C_0710 NC_011601.1 759443 759772 D minor tail protein 759443..759772 Escherichia coli O127:H6 str. E2348/69 7063619 YP_002328280.1 CDS E2348C_0711 NC_011601.1 759772 760470 D minor tail protein 759772..760470 Escherichia coli O127:H6 str. E2348/69 7063620 YP_002328281.1 CDS E2348C_0712 NC_011601.1 760476 761219 D tail assembly protein 760476..761219 Escherichia coli O127:H6 str. E2348/69 7063621 YP_002328282.1 CDS E2348C_0713 NC_011601.1 761117 761758 D tail assembly protein 761117..761758 Escherichia coli O127:H6 str. E2348/69 7063622 YP_002328283.1 CDS E2348C_0714 NC_011601.1 761819 765232 D host specificity protein 761819..765232 Escherichia coli O127:H6 str. E2348/69 7063623 YP_002328284.1 CDS E2348C_0715 NC_011601.1 765302 765901 D outer membrane precursor Lom 765302..765901 Escherichia coli O127:H6 str. E2348/69 7063624 YP_002328285.1 CDS E2348C_0716 NC_011601.1 765966 767279 D side tail fiber protein 765966..767279 Escherichia coli O127:H6 str. E2348/69 7063625 YP_002328286.1 CDS E2348C_0717 NC_011601.1 767281 767550 D hypothetical protein 767281..767550 Escherichia coli O127:H6 str. E2348/69 7063626 YP_002328287.1 CDS E2348C_0718 NC_011601.1 767656 768537 D T3SS secreted effector NleH-like protein 767656..768537 Escherichia coli O127:H6 str. E2348/69 7063627 YP_002328288.1 CDS E2348C_0721 NC_011601.1 770013 770393 D hypothetical protein 770013..770393 Escherichia coli O127:H6 str. E2348/69 7063629 YP_002328289.1 CDS E2348C_0722 NC_011601.1 770477 770698 D hypothetical protein 770477..770698 Escherichia coli O127:H6 str. E2348/69 7063630 YP_002328290.1 CDS E2348C_0723 NC_011601.1 770711 771364 R T3SS secreted effector EspJ-like protein complement(770711..771364) Escherichia coli O127:H6 str. E2348/69 7063631 YP_002328291.1 CDS ybhB NC_011601.1 771868 772344 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(771868..772344) Escherichia coli O127:H6 str. E2348/69 7063632 YP_002328292.1 CDS gipA NC_011601.1 772453 773583 D Peyer's patch-specific virulence factor GipA, transposase-like 772453..773583 Escherichia coli O127:H6 str. E2348/69 7063279 YP_002328293.1 CDS bioA NC_011601.1 773694 774983 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(773694..774983) Escherichia coli O127:H6 str. E2348/69 7061657 YP_002328294.1 CDS bioB NC_011601.1 775070 776110 D biotin synthase 775070..776110 Escherichia coli O127:H6 str. E2348/69 7062520 YP_002328295.1 CDS bioF NC_011601.1 776107 777261 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 776107..777261 Escherichia coli O127:H6 str. E2348/69 7062521 YP_002328296.1 CDS bioC NC_011601.1 777248 778003 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 777248..778003 Escherichia coli O127:H6 str. E2348/69 7062524 YP_002328297.1 CDS bioD NC_011601.1 777996 778673 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 777996..778673 Escherichia coli O127:H6 str. E2348/69 7062522 YP_002328298.1 CDS uvrB NC_011601.1 779252 781273 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 779252..781273 Escherichia coli O127:H6 str. E2348/69 7062523 YP_002328299.1 CDS ybhK NC_011601.1 781311 782219 R transferase with NAD(P)-binding Rossmann-fold domain complement(781311..782219) Escherichia coli O127:H6 str. E2348/69 7062341 YP_002328300.1 CDS moaA NC_011601.1 782616 783605 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 782616..783605 Escherichia coli O127:H6 str. E2348/69 7063287 YP_002328301.1 CDS moaB NC_011601.1 783627 784139 D molybdopterin biosynthesis protein B 783627..784139 Escherichia coli O127:H6 str. E2348/69 7063805 YP_002328302.1 CDS moaC NC_011601.1 784142 784627 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 784142..784627 Escherichia coli O127:H6 str. E2348/69 7063806 YP_002328303.1 CDS moaD NC_011601.1 784620 784865 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 784620..784865 Escherichia coli O127:H6 str. E2348/69 7063807 YP_002328304.1 CDS moaE NC_011601.1 784867 785319 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 784867..785319 Escherichia coli O127:H6 str. E2348/69 7063808 YP_002328305.1 CDS ybhL NC_011601.1 785456 786160 D hypothetical protein 785456..786160 Escherichia coli O127:H6 str. E2348/69 7063809 YP_002328306.1 CDS ybhM NC_011601.1 786365 787078 D hypothetical protein 786365..787078 Escherichia coli O127:H6 str. E2348/69 7063288 YP_002328307.1 CDS ybhN NC_011601.1 787114 788070 R hypothetical protein complement(787114..788070) Escherichia coli O127:H6 str. E2348/69 7063289 YP_002328308.1 CDS ybhO NC_011601.1 788070 789311 R cardiolipin synthase 2 complement(788070..789311) Escherichia coli O127:H6 str. E2348/69 7063290 YP_002328309.1 CDS ybhP NC_011601.1 789308 790069 R DNase complement(789308..790069) Escherichia coli O127:H6 str. E2348/69 7063291 YP_002328310.1 CDS ybhQ NC_011601.1 790202 790612 D hypothetical protein 790202..790612 Escherichia coli O127:H6 str. E2348/69 7063292 YP_002328311.1 CDS ybhR NC_011601.1 790574 791680 R DNase complement(790574..791680) Escherichia coli O127:H6 str. E2348/69 7063293 YP_002328312.1 CDS ybhS NC_011601.1 791691 792824 R transporter subunit: membrane component of ABC superfamily complement(791691..792824) Escherichia coli O127:H6 str. E2348/69 7063294 YP_002328313.1 CDS ybhF NC_011601.1 792817 794553 R fused transporter subunits of ABC superfamily: ATP-binding components complement(792817..794553) Escherichia coli O127:H6 str. E2348/69 7063295 YP_002328314.1 CDS ybhG NC_011601.1 794546 795544 R hypothetical protein complement(794546..795544) Escherichia coli O127:H6 str. E2348/69 7063282 YP_002328315.1 CDS ybiH NC_011601.1 795544 796215 R DNA-binding transcriptional regulator complement(795544..796215) Escherichia coli O127:H6 str. E2348/69 7063283 YP_002328316.1 CDS rhlE NC_011601.1 796444 797805 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 796444..797805 Escherichia coli O127:H6 str. E2348/69 7063300 YP_002328317.1 CDS dinG NC_011601.1 798342 800492 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 798342..800492 Escherichia coli O127:H6 str. E2348/69 7063297 YP_002328318.1 CDS ybiB NC_011601.1 800520 801482 D glycosyl transferase family protein 800520..801482 Escherichia coli O127:H6 str. E2348/69 7065031 YP_002328319.1 CDS ybiC NC_011601.1 801623 802708 D hypothetical protein 801623..802708 Escherichia coli O127:H6 str. E2348/69 7063298 YP_002328320.1 CDS ybiJ NC_011601.1 802936 803196 R hypothetical protein complement(802936..803196) Escherichia coli O127:H6 str. E2348/69 7063299 YP_002328321.1 CDS ybiI NC_011601.1 803461 803727 R hypothetical protein complement(803461..803727) Escherichia coli O127:H6 str. E2348/69 7063302 YP_002328322.1 CDS ybiX NC_011601.1 803801 804478 R hydroxylase complement(803801..804478) Escherichia coli O127:H6 str. E2348/69 7063301 YP_002328323.1 CDS fiu NC_011601.1 804520 806802 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(804520..806802) Escherichia coli O127:H6 str. E2348/69 7063312 YP_002328324.1 CDS ybiM NC_011601.1 807067 807327 R hypothetical protein complement(807067..807327) Escherichia coli O127:H6 str. E2348/69 7062129 YP_002328325.1 CDS ybiN NC_011601.1 807603 808529 D SAM-dependent methyltransferase 807603..808529 Escherichia coli O127:H6 str. E2348/69 7063303 YP_002328326.1 CDS ybiO NC_011601.1 808526 810751 R hypothetical protein complement(808526..810751) Escherichia coli O127:H6 str. E2348/69 7063304 YP_002328327.1 CDS glnQ NC_011601.1 810868 811590 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(810868..811590) Escherichia coli O127:H6 str. E2348/69 7063305 YP_002328328.1 CDS glnP NC_011601.1 811587 812246 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(811587..812246) Escherichia coli O127:H6 str. E2348/69 7061685 YP_002328329.1 CDS glnH NC_011601.1 812388 813134 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(812388..813134) Escherichia coli O127:H6 str. E2348/69 7061684 YP_002328330.1 CDS dps NC_011601.1 813538 814041 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(813538..814041) Escherichia coli O127:H6 str. E2348/69 7061681 YP_002328331.1 CDS rhtA NC_011601.1 814341 815228 R threonine and homoserine efflux system complement(814341..815228) Escherichia coli O127:H6 str. E2348/69 7065061 YP_002328332.1 CDS ompX NC_011601.1 815581 816096 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 815581..816096 Escherichia coli O127:H6 str. E2348/69 7060814 YP_002328333.1 CDS E2348C_0767 NC_011601.1 816286 816744 D transposase of IS200C 816286..816744 Escherichia coli O127:H6 str. E2348/69 7064967 YP_002328334.1 CDS ybiP NC_011601.1 816857 818440 R hydrolase, inner membrane complement(816857..818440) Escherichia coli O127:H6 str. E2348/69 7063633 YP_002328335.1 CDS mntR NC_011601.1 819026 819493 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 819026..819493 Escherichia coli O127:H6 str. E2348/69 7064591 YP_002328336.1 CDS ybiR NC_011601.1 819490 820608 D transporter 819490..820608 Escherichia coli O127:H6 str. E2348/69 7063804 YP_002328337.1 CDS ybiS NC_011601.1 820666 821586 R hypothetical protein complement(820666..821586) Escherichia coli O127:H6 str. E2348/69 7063307 YP_002328338.1 CDS ybiT NC_011601.1 821805 823397 D fused transporter subunits of ABC superfamily: ATP-binding components 821805..823397 Escherichia coli O127:H6 str. E2348/69 7063308 YP_002328339.1 CDS ybiV NC_011601.1 823597 824412 R hydrolase complement(823597..824412) Escherichia coli O127:H6 str. E2348/69 7063309 YP_002328340.1 CDS ybiW NC_011601.1 824557 826989 R pyruvate formate lyase complement(824557..826989) Escherichia coli O127:H6 str. E2348/69 7063310 YP_002328341.1 CDS ybiY NC_011601.1 826995 827894 R pyruvate formate lyase activating enzyme complement(826995..827894) Escherichia coli O127:H6 str. E2348/69 7063311 YP_002328342.1 CDS fsaA NC_011601.1 828025 828687 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 828025..828687 Escherichia coli O127:H6 str. E2348/69 7063313 YP_002328343.1 CDS moeB NC_011601.1 828763 829512 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(828763..829512) Escherichia coli O127:H6 str. E2348/69 7061973 YP_002328344.1 CDS moeA NC_011601.1 829512 830747 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(829512..830747) Escherichia coli O127:H6 str. E2348/69 7063818 YP_002328345.1 CDS iaaA NC_011601.1 830951 831916 D L-asparaginase 830951..831916 Escherichia coli O127:H6 str. E2348/69 7063817 YP_002328346.1 CDS gsiA NC_011601.1 831903 833774 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 831903..833774 Escherichia coli O127:H6 str. E2348/69 7063512 YP_002328347.1 CDS gsiB NC_011601.1 833794 835332 D peptide transporter subunit: periplasmic-binding component of ABC superfamily 833794..835332 Escherichia coli O127:H6 str. E2348/69 7064252 YP_002328348.1 CDS gsiC NC_011601.1 835350 836270 D peptide transporter subunit: membrane component of ABC superfamily 835350..836270 Escherichia coli O127:H6 str. E2348/69 7064253 YP_002328349.1 CDS gsiD NC_011601.1 836273 837184 D peptide transporter subunit: membrane component of ABC superfamily 836273..837184 Escherichia coli O127:H6 str. E2348/69 7064254 YP_002328350.1 CDS yliE NC_011601.1 837361 839709 D hypothetical protein 837361..839709 Escherichia coli O127:H6 str. E2348/69 7064255 YP_002328351.1 CDS yliF NC_011601.1 839717 841045 D diguanylate cyclase 839717..841045 Escherichia coli O127:H6 str. E2348/69 7062015 YP_002328352.1 CDS rimO NC_011601.1 841092 842417 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(841092..842417) Escherichia coli O127:H6 str. E2348/69 7062016 YP_002328353.1 CDS bssR NC_011601.1 842630 843013 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 842630..843013 Escherichia coli O127:H6 str. E2348/69 7062017 YP_002328354.1 CDS yliI NC_011601.1 843124 844239 D dehydrogenase 843124..844239 Escherichia coli O127:H6 str. E2348/69 7062532 YP_002328355.1 CDS yliJ NC_011601.1 844236 844862 R glutathione S-transferase complement(844236..844862) Escherichia coli O127:H6 str. E2348/69 7062018 YP_002328356.1 CDS dacC NC_011601.1 845109 846311 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 845109..846311 Escherichia coli O127:H6 str. E2348/69 7062019 YP_002328357.1 CDS deoR NC_011601.1 846358 847116 R DNA-binding transcriptional repressor DeoR complement(846358..847116) Escherichia coli O127:H6 str. E2348/69 7065214 YP_002328358.1 CDS ybjG NC_011601.1 847174 847770 R undecaprenyl pyrophosphate phosphatase complement(847174..847770) Escherichia coli O127:H6 str. E2348/69 7065011 YP_002328359.1 CDS cmr NC_011601.1 848055 849287 D multidrug efflux system protein 848055..849287 Escherichia coli O127:H6 str. E2348/69 7063317 YP_002328360.1 CDS ybjH NC_011601.1 849328 849612 R hypothetical protein complement(849328..849612) Escherichia coli O127:H6 str. E2348/69 7062817 YP_002328361.1 CDS ybjI NC_011601.1 849698 850513 R hypothetical protein complement(849698..850513) Escherichia coli O127:H6 str. E2348/69 7063318 YP_002328362.1 CDS ybjJ NC_011601.1 850513 851721 R transporter complement(850513..851721) Escherichia coli O127:H6 str. E2348/69 7063319 YP_002328363.1 CDS ybjK NC_011601.1 851805 852341 D DNA-binding transcriptional regulator 851805..852341 Escherichia coli O127:H6 str. E2348/69 7063320 YP_002328364.1 CDS E2348C_0798 NC_011601.1 852446 853498 R integrase complement(852446..853498) Escherichia coli O127:H6 str. E2348/69 7061167 YP_002328365.1 CDS E2348C_0799 NC_011601.1 853585 855102 R hypothetical protein complement(853585..855102) Escherichia coli O127:H6 str. E2348/69 7063634 YP_002328366.1 CDS E2348C_0800 NC_011601.1 855128 856051 R hypothetical protein complement(855128..856051) Escherichia coli O127:H6 str. E2348/69 7063635 YP_002328367.1 CDS E2348C_0801 NC_011601.1 856102 856671 R repressor protein complement(856102..856671) Escherichia coli O127:H6 str. E2348/69 7063636 YP_002328368.1 CDS E2348C_0802 NC_011601.1 856797 857018 D regulatory protein 856797..857018 Escherichia coli O127:H6 str. E2348/69 7063637 YP_002328369.1 CDS E2348C_0803 NC_011601.1 857051 857560 D regulatory protein 857051..857560 Escherichia coli O127:H6 str. E2348/69 7063638 YP_002328370.1 CDS E2348C_0804 NC_011601.1 857568 857768 D hypothetical protein 857568..857768 Escherichia coli O127:H6 str. E2348/69 7063639 YP_002328371.1 CDS E2348C_0805 NC_011601.1 857732 858073 D hypothetical protein 857732..858073 Escherichia coli O127:H6 str. E2348/69 7063640 YP_002328372.1 CDS E2348C_0806 NC_011601.1 858141 858374 D hypothetical protein 858141..858374 Escherichia coli O127:H6 str. E2348/69 7063641 YP_002328373.1 CDS E2348C_0807 NC_011601.1 858374 858601 D TraR/DksA family transcriptional regulator 858374..858601 Escherichia coli O127:H6 str. E2348/69 7063642 YP_002328374.1 CDS E2348C_0808 NC_011601.1 858598 859455 D DNA adenine methylase 858598..859455 Escherichia coli O127:H6 str. E2348/69 7063643 YP_002328375.1 CDS E2348C_0809 NC_011601.1 859452 861866 D replication protein 859452..861866 Escherichia coli O127:H6 str. E2348/69 7063644 YP_002328376.1 CDS E2348C_0810 NC_011601.1 862021 862209 D hypothetical protein 862021..862209 Escherichia coli O127:H6 str. E2348/69 7063645 YP_002328377.1 CDS E2348C_0811 NC_011601.1 862220 862453 D DNA-damage-inducible protein 862220..862453 Escherichia coli O127:H6 str. E2348/69 7063646 YP_002328378.1 CDS E2348C_0812 NC_011601.1 862646 862981 R hypothetical protein complement(862646..862981) Escherichia coli O127:H6 str. E2348/69 7063647 YP_002328379.1 CDS E2348C_0813 NC_011601.1 863253 863525 D hypothetical protein 863253..863525 Escherichia coli O127:H6 str. E2348/69 7063648 YP_002328380.1 CDS E2348C_0814 NC_011601.1 863510 864085 D hypothetical protein 863510..864085 Escherichia coli O127:H6 str. E2348/69 7063649 YP_002328381.1 CDS E2348C_0815 NC_011601.1 864090 865049 D hypothetical protein 864090..865049 Escherichia coli O127:H6 str. E2348/69 7063650 YP_002328382.1 CDS E2348C_0816 NC_011601.1 865074 866099 R capsid portal protein complement(865074..866099) Escherichia coli O127:H6 str. E2348/69 7063651 YP_002328383.1 CDS E2348C_0817 NC_011601.1 866099 867865 R terminase, ATPase subunit complement(866099..867865) Escherichia coli O127:H6 str. E2348/69 7063652 YP_002328384.1 CDS E2348C_0818 NC_011601.1 868008 868841 D capsid scaffolding protein 868008..868841 Escherichia coli O127:H6 str. E2348/69 7063653 YP_002328385.1 CDS E2348C_0819 NC_011601.1 868858 869916 D major capsid protein 868858..869916 Escherichia coli O127:H6 str. E2348/69 7063654 YP_002328386.1 CDS E2348C_0820 NC_011601.1 869920 870570 D terminase, endonuclease subunit 869920..870570 Escherichia coli O127:H6 str. E2348/69 7063655 YP_002328387.1 CDS E2348C_0821 NC_011601.1 870666 871130 D capsid completion protein 870666..871130 Escherichia coli O127:H6 str. E2348/69 7063656 YP_002328388.1 CDS E2348C_0822 NC_011601.1 871130 871333 D tail protein 871130..871333 Escherichia coli O127:H6 str. E2348/69 7063657 YP_002328389.1 CDS E2348C_0823 NC_011601.1 871337 871552 D secretory protein 871337..871552 Escherichia coli O127:H6 str. E2348/69 7063658 YP_002328390.1 CDS E2348C_0824 NC_011601.1 871533 872045 D lysozyme 871533..872045 Escherichia coli O127:H6 str. E2348/69 7063659 YP_002328391.1 CDS E2348C_0825 NC_011601.1 872047 872424 D membrane protein 872047..872424 Escherichia coli O127:H6 str. E2348/69 7063660 YP_002328392.1 CDS E2348C_0826 NC_011601.1 872421 872849 D regulatory protein 872421..872849 Escherichia coli O127:H6 str. E2348/69 7063661 YP_002328393.1 CDS E2348C_0827 NC_011601.1 872945 873376 D tail protein 872945..873376 Escherichia coli O127:H6 str. E2348/69 7063662 YP_002328394.1 CDS E2348C_0829 NC_011601.1 873731 874792 R variable tail fiber protein complement(873731..874792) Escherichia coli O127:H6 str. E2348/69 7060860 YP_002328395.1 CDS E2348C_0830 NC_011601.1 874789 875394 R tail protein complement(874789..875394) Escherichia coli O127:H6 str. E2348/69 7061019 YP_002328396.1 CDS E2348C_0831 NC_011601.1 875387 876295 R baseplate assembly protein complement(875387..876295) Escherichia coli O127:H6 str. E2348/69 7061020 YP_002328397.1 CDS E2348C_0832 NC_011601.1 876282 876641 R baseplate assembly protein complement(876282..876641) Escherichia coli O127:H6 str. E2348/69 7061021 YP_002328398.1 CDS E2348C_0833 NC_011601.1 876638 877216 R baseplate assembly protein complement(876638..877216) Escherichia coli O127:H6 str. E2348/69 7061022 YP_002328399.1 CDS E2348C_0834 NC_011601.1 877308 878453 D hypothetical protein 877308..878453 Escherichia coli O127:H6 str. E2348/69 7061023 YP_002328400.1 CDS E2348C_0835 NC_011601.1 878571 879137 D DNA invertase 878571..879137 Escherichia coli O127:H6 str. E2348/69 7061024 YP_002328401.1 CDS E2348C_0836 NC_011601.1 879280 880452 D major tail sheath protein 879280..880452 Escherichia coli O127:H6 str. E2348/69 7061025 YP_002328402.1 CDS E2348C_0837 NC_011601.1 880462 880977 D major tail tube protein 880462..880977 Escherichia coli O127:H6 str. E2348/69 7061026 YP_002328403.1 CDS E2348C_0838 NC_011601.1 881032 881334 D tail protein 881032..881334 Escherichia coli O127:H6 str. E2348/69 7061027 YP_002328404.1 CDS E2348C_0839 NC_011601.1 881349 881468 D tail protein 881349..881468 Escherichia coli O127:H6 str. E2348/69 7061028 YP_002328405.1 CDS E2348C_0840 NC_011601.1 881461 884538 D tail tape measure protein 881461..884538 Escherichia coli O127:H6 str. E2348/69 7061029 YP_002328406.1 CDS E2348C_0841 NC_011601.1 884535 885020 D tail protein 884535..885020 Escherichia coli O127:H6 str. E2348/69 7061030 YP_002328407.1 CDS E2348C_0842 NC_011601.1 885017 886117 D late gene regulator 885017..886117 Escherichia coli O127:H6 str. E2348/69 7061031 YP_002328408.1 CDS E2348C_0843 NC_011601.1 886205 886423 D transcriptional activator 886205..886423 Escherichia coli O127:H6 str. E2348/69 7061032 YP_002328409.1 CDS ybjL NC_011601.1 886659 888344 R hypothetical protein complement(886659..888344) Escherichia coli O127:H6 str. E2348/69 7064592 YP_002328410.1 CDS ybjM NC_011601.1 888614 888991 D hypothetical protein 888614..888991 Escherichia coli O127:H6 str. E2348/69 7063322 YP_002328411.1 CDS grxA NC_011601.1 889021 889278 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(889021..889278) Escherichia coli O127:H6 str. E2348/69 7063323 YP_002328412.1 CDS ybjC NC_011601.1 889438 889725 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 889438..889725 Escherichia coli O127:H6 str. E2348/69 7064246 YP_002328413.1 CDS nfsA NC_011601.1 889709 890431 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 889709..890431 Escherichia coli O127:H6 str. E2348/69 7063314 YP_002328414.1 CDS rimK NC_011601.1 890492 891394 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 890492..891394 Escherichia coli O127:H6 str. E2348/69 7065385 YP_002328415.1 CDS ybjN NC_011601.1 891482 891958 D oxidoreductase 891482..891958 Escherichia coli O127:H6 str. E2348/69 7060829 YP_002328416.1 CDS potF NC_011601.1 892308 893420 D putrescine ABC transporter periplasmic-binding protein 892308..893420 Escherichia coli O127:H6 str. E2348/69 7063324 YP_002328417.1 CDS potG NC_011601.1 893515 894648 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 893515..894648 Escherichia coli O127:H6 str. E2348/69 7060775 YP_002328418.1 CDS potH NC_011601.1 894658 895611 D putrescine ABC transporter membrane protein 894658..895611 Escherichia coli O127:H6 str. E2348/69 7060776 YP_002328419.1 CDS potI NC_011601.1 895608 896453 D putrescine ABC transporter membrane protein 895608..896453 Escherichia coli O127:H6 str. E2348/69 7060777 YP_002328420.1 CDS ybjO NC_011601.1 896513 897001 D hypothetical protein 896513..897001 Escherichia coli O127:H6 str. E2348/69 7060778 YP_002328421.1 CDS rumB NC_011601.1 897042 898169 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 897042..898169 Escherichia coli O127:H6 str. E2348/69 7063325 YP_002328422.1 CDS artJ NC_011601.1 898198 898929 R arginine ABC transporter substrate-binding protein complement(898198..898929) Escherichia coli O127:H6 str. E2348/69 7064579 YP_002328423.1 CDS artM NC_011601.1 899155 899823 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(899155..899823) Escherichia coli O127:H6 str. E2348/69 7061403 YP_002328424.1 CDS artQ NC_011601.1 899823 900539 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(899823..900539) Escherichia coli O127:H6 str. E2348/69 7061404 YP_002328425.1 CDS artI NC_011601.1 900546 901277 R arginine transporter subunit complement(900546..901277) Escherichia coli O127:H6 str. E2348/69 7061406 YP_002328426.1 CDS artP NC_011601.1 901295 902023 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(901295..902023) Escherichia coli O127:H6 str. E2348/69 7061402 YP_002328427.1 CDS ybjP NC_011601.1 902241 902756 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(902241..902756) Escherichia coli O127:H6 str. E2348/69 7061405 YP_002328428.1 CDS ybjQ NC_011601.1 902882 903205 D hypothetical protein 902882..903205 Escherichia coli O127:H6 str. E2348/69 7063326 YP_002328429.1 CDS ybjR NC_011601.1 903202 904032 D amidase 903202..904032 Escherichia coli O127:H6 str. E2348/69 7063327 YP_002328430.1 CDS ybjS NC_011601.1 904029 905042 R NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain complement(904029..905042) Escherichia coli O127:H6 str. E2348/69 7063328 YP_002328431.1 CDS ybjT NC_011601.1 905141 906571 R hypothetical protein complement(905141..906571) Escherichia coli O127:H6 str. E2348/69 7063329 YP_002328432.1 CDS ltaE NC_011601.1 906582 907583 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(906582..907583) Escherichia coli O127:H6 str. E2348/69 7063330 YP_002328433.1 CDS poxB NC_011601.1 907620 909338 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(907620..909338) Escherichia coli O127:H6 str. E2348/69 7065248 YP_002328434.1 CDS hcr NC_011601.1 909471 910439 R HCP oxidoreductase complement(909471..910439) Escherichia coli O127:H6 str. E2348/69 7061261 YP_002328435.1 CDS hcp NC_011601.1 910451 912103 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(910451..912103) Escherichia coli O127:H6 str. E2348/69 7064283 YP_002328436.1 CDS ybjE NC_011601.1 912247 913146 R transporter complement(912247..913146) Escherichia coli O127:H6 str. E2348/69 7064282 YP_002328437.1 CDS aqpZ NC_011601.1 913630 914325 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(913630..914325) Escherichia coli O127:H6 str. E2348/69 7063316 YP_002328438.1 CDS ybjD NC_011601.1 914751 916409 D hypothetical protein 914751..916409 Escherichia coli O127:H6 str. E2348/69 7061355 YP_002328439.1 CDS ybjX NC_011601.1 916406 917398 R hypothetical protein complement(916406..917398) Escherichia coli O127:H6 str. E2348/69 7063315 YP_002328440.1 CDS macA NC_011601.1 917513 918628 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 917513..918628 Escherichia coli O127:H6 str. E2348/69 7063331 YP_002328441.1 CDS macB NC_011601.1 918625 920571 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 918625..920571 Escherichia coli O127:H6 str. E2348/69 7065265 YP_002328442.1 CDS cspD NC_011601.1 920644 920868 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(920644..920868) Escherichia coli O127:H6 str. E2348/69 7065266 YP_002328443.1 CDS clpS NC_011601.1 921191 921511 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 921191..921511 Escherichia coli O127:H6 str. E2348/69 7062862 YP_002328444.1 CDS clpA NC_011601.1 921542 923818 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 921542..923818 Escherichia coli O127:H6 str. E2348/69 7062811 YP_002328445.1 CDS infA NC_011601.1 924621 924839 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(924621..924839) Escherichia coli O127:H6 str. E2348/69 7062704 YP_002328446.1 CDS aat NC_011601.1 925124 925828 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(925124..925828) Escherichia coli O127:H6 str. E2348/69 7063542 YP_002328447.1 CDS cydC NC_011601.1 925870 927591 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(925870..927591) Escherichia coli O127:H6 str. E2348/69 7061178 YP_002328448.1 CDS cydD NC_011601.1 927592 929358 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(927592..929358) Escherichia coli O127:H6 str. E2348/69 7065186 YP_002328449.1 CDS trxB NC_011601.1 929481 930446 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(929481..930446) Escherichia coli O127:H6 str. E2348/69 7065187 YP_002328450.1 CDS lrp NC_011601.1 930991 931485 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 930991..931485 Escherichia coli O127:H6 str. E2348/69 7062268 YP_002328451.1 CDS ftsK NC_011601.1 931620 935726 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 931620..935726 Escherichia coli O127:H6 str. E2348/69 7065246 YP_002328452.1 CDS lolA NC_011601.1 935882 936496 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 935882..936496 Escherichia coli O127:H6 str. E2348/69 7061585 YP_002328453.1 CDS rarA NC_011601.1 936507 937850 D recombination factor protein RarA 936507..937850 Escherichia coli O127:H6 str. E2348/69 7061554 YP_002328454.1 CDS serS NC_011601.1 937941 939233 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 937941..939233 Escherichia coli O127:H6 str. E2348/69 7063948 YP_002328455.1 CDS dmsB NC_011601.1 941927 942544 D dimethyl sulfoxide reductase, anaerobic subunit B 941927..942544 Escherichia coli O127:H6 str. E2348/69 7065040 YP_002328456.1 CDS dmsC NC_011601.1 942546 943409 D dimethyl sulfoxide reductase, anaerobic subunit C 942546..943409 Escherichia coli O127:H6 str. E2348/69 7065041 YP_002328457.1 CDS ycaD NC_011601.1 944302 945450 D MFS family transporter protein 944302..945450 Escherichia coli O127:H6 str. E2348/69 7063332 YP_002328458.1 CDS pflA NC_011601.1 945547 946287 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(945547..946287) Escherichia coli O127:H6 str. E2348/69 7063333 YP_002328459.1 CDS pflB NC_011601.1 946479 948761 R pyruvate formate lyase I complement(946479..948761) Escherichia coli O127:H6 str. E2348/69 7060708 YP_002328460.1 CDS focA NC_011601.1 948816 949673 R formate transporter complement(948816..949673) Escherichia coli O127:H6 str. E2348/69 7060709 YP_002328461.1 CDS ycaO NC_011601.1 950079 951839 R hypothetical protein complement(950079..951839) Escherichia coli O127:H6 str. E2348/69 7061937 YP_002328462.1 CDS ycaP NC_011601.1 951969 952661 D hypothetical protein 951969..952661 Escherichia coli O127:H6 str. E2348/69 7063336 YP_002328463.1 CDS serC NC_011601.1 952860 953948 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 952860..953948 Escherichia coli O127:H6 str. E2348/69 7063337 YP_002328464.1 CDS aroA NC_011601.1 954019 955302 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 954019..955302 Escherichia coli O127:H6 str. E2348/69 7065368 YP_002328465.1 CDS ycaL NC_011601.1 955472 956236 D peptidase with chaperone function 955472..956236 Escherichia coli O127:H6 str. E2348/69 7061389 YP_002328466.1 CDS cmk NC_011601.1 956409 957092 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 956409..957092 Escherichia coli O127:H6 str. E2348/69 7063335 YP_002328467.1 CDS rpsA NC_011601.1 957203 958876 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 957203..958876 Escherichia coli O127:H6 str. E2348/69 7062814 YP_002328468.1 CDS ihfB NC_011601.1 959036 959320 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 959036..959320 Escherichia coli O127:H6 str. E2348/69 7061873 YP_002328469.1 CDS ycaI NC_011601.1 959526 961790 D hypothetical protein 959526..961790 Escherichia coli O127:H6 str. E2348/69 7063521 YP_002328470.1 CDS msbA NC_011601.1 961827 963575 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 961827..963575 Escherichia coli O127:H6 str. E2348/69 7063334 YP_002328471.1 CDS lpxK NC_011601.1 963572 964558 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 963572..964558 Escherichia coli O127:H6 str. E2348/69 7060871 YP_002328472.1 CDS ycaQ NC_011601.1 964595 965827 D hypothetical protein 964595..965827 Escherichia coli O127:H6 str. E2348/69 7061577 YP_002328473.1 CDS ycaR NC_011601.1 965879 966061 D hypothetical protein 965879..966061 Escherichia coli O127:H6 str. E2348/69 7063338 YP_002328474.1 CDS kdsB NC_011601.1 966058 966804 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 966058..966804 Escherichia coli O127:H6 str. E2348/69 7063339 YP_002328475.1 CDS ycbJ NC_011601.1 966958 967851 D hypothetical protein 966958..967851 Escherichia coli O127:H6 str. E2348/69 7063579 YP_002328476.1 CDS ycbC NC_011601.1 967828 968607 R hypothetical protein complement(967828..968607) Escherichia coli O127:H6 str. E2348/69 7061419 YP_002328477.1 CDS smtA NC_011601.1 968743 969528 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 968743..969528 Escherichia coli O127:H6 str. E2348/69 7063341 YP_002328478.1 CDS mukF NC_011601.1 969525 970847 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 969525..970847 Escherichia coli O127:H6 str. E2348/69 7062731 YP_002328479.1 CDS mukE NC_011601.1 970828 971532 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 970828..971532 Escherichia coli O127:H6 str. E2348/69 7060886 YP_002328480.1 CDS mukB NC_011601.1 971532 975992 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 971532..975992 Escherichia coli O127:H6 str. E2348/69 7060885 YP_002328481.1 CDS ycbB NC_011601.1 976253 978100 D hypothetical protein 976253..978100 Escherichia coli O127:H6 str. E2348/69 7060884 YP_002328482.1 CDS ycbK NC_011601.1 978281 978829 D hypothetical protein 978281..978829 Escherichia coli O127:H6 str. E2348/69 7063340 YP_002328483.1 CDS ycbL NC_011601.1 978856 979503 D metal-binding enzyme 978856..979503 Escherichia coli O127:H6 str. E2348/69 7061420 YP_002328484.1 CDS aspC NC_011601.1 979553 980743 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(979553..980743) Escherichia coli O127:H6 str. E2348/69 7061421 YP_002328485.1 CDS ompF NC_011601.1 980927 981997 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(980927..981997) Escherichia coli O127:H6 str. E2348/69 7062459 YP_002328486.1 CDS asnC NC_011601.1 982600 984000 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(982600..984000) Escherichia coli O127:H6 str. E2348/69 7062875 YP_002328487.1 CDS pncB NC_011601.1 984169 985371 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(984169..985371) Escherichia coli O127:H6 str. E2348/69 7061414 YP_002328488.1 CDS pepN NC_011601.1 985637 988249 D aminopeptidase 985637..988249 Escherichia coli O127:H6 str. E2348/69 7060762 YP_002328489.1 CDS ssuB NC_011601.1 988455 989222 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(988455..989222) Escherichia coli O127:H6 str. E2348/69 7060702 YP_002328490.1 CDS ssuC NC_011601.1 989219 990010 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease complement(989219..990010) Escherichia coli O127:H6 str. E2348/69 7062771 YP_002328491.1 CDS ssuD NC_011601.1 990022 991167 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(990022..991167) Escherichia coli O127:H6 str. E2348/69 7062772 YP_002328492.1 CDS ssuA NC_011601.1 991164 992123 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(991164..992123) Escherichia coli O127:H6 str. E2348/69 7062773 YP_002328493.1 CDS ssuE NC_011601.1 992116 992691 R NAD(P)H-dependent FMN reductase complement(992116..992691) Escherichia coli O127:H6 str. E2348/69 7062770 YP_002328494.1 CDS pyrD NC_011601.1 992928 993938 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 992928..993938 Escherichia coli O127:H6 str. E2348/69 7062774 YP_002328495.1 CDS ycbW NC_011601.1 994112 994654 D hypothetical protein 994112..994654 Escherichia coli O127:H6 str. E2348/69 7063931 YP_002328496.1 CDS ycbX NC_011601.1 994651 995760 R 2Fe-2S cluster-containing protein complement(994651..995760) Escherichia coli O127:H6 str. E2348/69 7061422 YP_002328497.1 CDS rlmL NC_011601.1 995858 997966 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 995858..997966 Escherichia coli O127:H6 str. E2348/69 7061423 YP_002328498.1 CDS uup NC_011601.1 997978 999885 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 997978..999885 Escherichia coli O127:H6 str. E2348/69 7060835 YP_002328499.1 CDS pqiA NC_011601.1 1000015 1001268 D paraquat-inducible membrane protein A 1000015..1001268 Escherichia coli O127:H6 str. E2348/69 7062339 YP_002328500.1 CDS pqiB NC_011601.1 1001273 1002913 D paraquat-inducible protein B 1001273..1002913 Escherichia coli O127:H6 str. E2348/69 7061280 YP_002328501.1 CDS ymbA NC_011601.1 1002910 1003473 D hypothetical protein 1002910..1003473 Escherichia coli O127:H6 str. E2348/69 7061281 YP_002328502.1 CDS rmf NC_011601.1 1003729 1003896 D ribosome modulation factor 1003729..1003896 Escherichia coli O127:H6 str. E2348/69 7062020 YP_002328503.1 CDS fabA NC_011601.1 1003966 1004484 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1003966..1004484) Escherichia coli O127:H6 str. E2348/69 7060844 YP_002328504.1 CDS ycbZ NC_011601.1 1004553 1006313 R peptidase complement(1004553..1006313) Escherichia coli O127:H6 str. E2348/69 7062062 YP_002328505.1 CDS ycbG NC_011601.1 1006499 1006951 D hypothetical protein 1006499..1006951 Escherichia coli O127:H6 str. E2348/69 7061424 YP_002328506.1 CDS ompA NC_011601.1 1007029 1008069 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1007029..1008069) Escherichia coli O127:H6 str. E2348/69 7063342 YP_002328507.1 CDS sulA NC_011601.1 1008425 1008934 R SOS cell division inhibitor complement(1008425..1008934) Escherichia coli O127:H6 str. E2348/69 7062873 YP_002328508.1 CDS yccR NC_011601.1 1009152 1009781 D hypothetical protein 1009152..1009781 Escherichia coli O127:H6 str. E2348/69 7061743 YP_002328509.1 CDS yccS NC_011601.1 1009744 1011897 R hypothetical protein complement(1009744..1011897) Escherichia coli O127:H6 str. E2348/69 7061430 YP_002328510.1 CDS yccF NC_011601.1 1011916 1012362 R hypothetical protein complement(1011916..1012362) Escherichia coli O127:H6 str. E2348/69 7061431 YP_002328511.1 CDS helD NC_011601.1 1012485 1014539 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1012485..1014539 Escherichia coli O127:H6 str. E2348/69 7061426 YP_002328512.1 CDS mgsA NC_011601.1 1014571 1015029 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1014571..1015029) Escherichia coli O127:H6 str. E2348/69 7064290 YP_002328513.1 CDS yccT NC_011601.1 1015125 1015787 R hypothetical protein complement(1015125..1015787) Escherichia coli O127:H6 str. E2348/69 7063781 YP_002328514.1 CDS yccU NC_011601.1 1015960 1016373 D CoA-binding protein with NAD(P)-binding Rossmann-fold domain 1015960..1016373 Escherichia coli O127:H6 str. E2348/69 7061432 YP_002328515.1 CDS hspQ NC_011601.1 1016418 1016735 R heat shock protein HspQ complement(1016418..1016735) Escherichia coli O127:H6 str. E2348/69 7061433 YP_002328516.1 CDS yccW NC_011601.1 1016793 1017983 R methyltransferase complement(1016793..1017983) Escherichia coli O127:H6 str. E2348/69 7062187 YP_002328517.1 CDS yccX NC_011601.1 1018078 1018356 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1018078..1018356 Escherichia coli O127:H6 str. E2348/69 7061434 YP_002328518.1 CDS yccK NC_011601.1 1018353 1018682 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1018353..1018682) Escherichia coli O127:H6 str. E2348/69 7061435 YP_002328519.1 CDS yccA NC_011601.1 1018774 1019433 R hypothetical protein complement(1018774..1019433) Escherichia coli O127:H6 str. E2348/69 7061428 YP_002328520.1 CDS hyaA NC_011601.1 1020154 1021272 D hydrogenase 1, small subunit 1020154..1021272 Escherichia coli O127:H6 str. E2348/69 7065370 YP_002328521.1 CDS hyaB NC_011601.1 1021269 1023062 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1021269..1023062 Escherichia coli O127:H6 str. E2348/69 7062195 YP_002328522.1 CDS hyaC NC_011601.1 1023081 1023788 D hydrogenase 1 b-type cytochrome subunit 1023081..1023788 Escherichia coli O127:H6 str. E2348/69 7062196 YP_002328523.1 CDS hyaD NC_011601.1 1023785 1024372 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1023785..1024372 Escherichia coli O127:H6 str. E2348/69 7062197 YP_002328524.1 CDS hyaE NC_011601.1 1024369 1024767 D involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1024369..1024767 Escherichia coli O127:H6 str. E2348/69 7062198 YP_002328525.1 CDS hyaF NC_011601.1 1024764 1025621 D HyaF protein involved in nickel incorporation into hydrogenase-1 proteins 1024764..1025621 Escherichia coli O127:H6 str. E2348/69 7062199 YP_002328526.1 CDS appC NC_011601.1 1025755 1027299 D cytochrome bd-II oxidase subunit I 1025755..1027299 Escherichia coli O127:H6 str. E2348/69 7062200 YP_002328527.1 CDS appB NC_011601.1 1027311 1028447 D cytochrome bd-II oxidase subunit II 1027311..1028447 Escherichia coli O127:H6 str. E2348/69 7061353 YP_002328528.1 CDS appA NC_011601.1 1028632 1029930 D phosphoanhydride phosphorylase 1028632..1029930 Escherichia coli O127:H6 str. E2348/69 7061352 YP_002328529.1 CDS etk NC_011601.1 1030051 1032231 R cryptic autophosphorylating protein tyrosine kinase Etk complement(1030051..1032231) Escherichia coli O127:H6 str. E2348/69 7061351 YP_002328530.1 CDS etp NC_011601.1 1032251 1032697 R Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase complement(1032251..1032697) Escherichia coli O127:H6 str. E2348/69 7063885 YP_002328531.1 CDS gfcE NC_011601.1 1032685 1033824 R exopolysaccharide export protein complement(1032685..1033824) Escherichia coli O127:H6 str. E2348/69 7063886 YP_002328532.1 CDS gfcD NC_011601.1 1033870 1035966 R hypothetical protein complement(1033870..1035966) Escherichia coli O127:H6 str. E2348/69 7061652 YP_002328533.1 CDS gfcC NC_011601.1 1035966 1036712 R hypothetical protein complement(1035966..1036712) Escherichia coli O127:H6 str. E2348/69 7061651 YP_002328534.1 CDS gfcB NC_011601.1 1036709 1037353 R outer membrane lipoprotein complement(1036709..1037353) Escherichia coli O127:H6 str. E2348/69 7061650 YP_002328535.1 CDS gfcA NC_011601.1 1037461 1037766 R hypothetical protein complement(1037461..1037766) Escherichia coli O127:H6 str. E2348/69 7061649 YP_002328536.1 CDS cspH NC_011601.1 1038208 1038420 R stress protein, member of the CspA-family complement(1038208..1038420) Escherichia coli O127:H6 str. E2348/69 7061648 YP_002328537.1 CDS cspG NC_011601.1 1038706 1038918 D cold shock protein CspG 1038706..1038918 Escherichia coli O127:H6 str. E2348/69 7062865 YP_002328538.1 CDS ymcE NC_011601.1 1039092 1039322 D cold shock gene 1039092..1039322 Escherichia coli O127:H6 str. E2348/69 7062864 YP_002328539.1 CDS gnsA NC_011601.1 1039312 1039485 D regulator of phosphatidylethanolamine synthesis 1039312..1039485 Escherichia coli O127:H6 str. E2348/69 7062021 YP_002328540.1 CDS yccM NC_011601.1 1039534 1040607 R (4Fe-4S)-binding protein complement(1039534..1040607) Escherichia coli O127:H6 str. E2348/69 7061735 YP_002328541.1 CDS torS NC_011601.1 1040690 1043422 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1040690..1043422) Escherichia coli O127:H6 str. E2348/69 7061429 YP_002328542.1 CDS E2348C_0979 NC_011601.1 1043517 1044590 R integrase complement(1043517..1044590) Escherichia coli O127:H6 str. E2348/69 7061168 YP_002328543.1 CDS E2348C_0980 NC_011601.1 1044568 1044786 R excisionase complement(1044568..1044786) Escherichia coli O127:H6 str. E2348/69 7061034 YP_002328544.1 CDS E2348C_0981 NC_011601.1 1044826 1044993 R hypothetical protein complement(1044826..1044993) Escherichia coli O127:H6 str. E2348/69 7061035 YP_002328545.1 CDS E2348C_0982 NC_011601.1 1045082 1045363 R hypothetical protein complement(1045082..1045363) Escherichia coli O127:H6 str. E2348/69 7061036 YP_002328546.1 CDS E2348C_0983 NC_011601.1 1045566 1046234 R hypothetical protein complement(1045566..1046234) Escherichia coli O127:H6 str. E2348/69 7061037 YP_002328547.1 CDS E2348C_0984 NC_011601.1 1046231 1046794 R hypothetical protein complement(1046231..1046794) Escherichia coli O127:H6 str. E2348/69 7061038 YP_002328548.1 CDS E2348C_0985 NC_011601.1 1046966 1047259 R anti-RecBCD protein complement(1046966..1047259) Escherichia coli O127:H6 str. E2348/69 7061039 YP_002328549.1 CDS E2348C_0986 NC_011601.1 1047273 1047779 R single-stranded DNA-binding protein complement(1047273..1047779) Escherichia coli O127:H6 str. E2348/69 7061040 YP_002328550.1 CDS E2348C_0987 NC_011601.1 1047780 1048487 R recombination protein complement(1047780..1048487) Escherichia coli O127:H6 str. E2348/69 7061041 YP_002328551.1 CDS E2348C_0988 NC_011601.1 1048496 1048666 R hypothetical protein complement(1048496..1048666) Escherichia coli O127:H6 str. E2348/69 7061042 YP_002328552.1 CDS E2348C_0989 NC_011601.1 1048587 1048745 R hypothetical protein complement(1048587..1048745) Escherichia coli O127:H6 str. E2348/69 7061043 YP_002328553.1 CDS E2348C_0990 NC_011601.1 1048742 1048894 R host killing protein complement(1048742..1048894) Escherichia coli O127:H6 str. E2348/69 7061044 YP_002328554.1 CDS E2348C_0991 NC_011601.1 1048879 1049013 R reguratory protein complement(1048879..1049013) Escherichia coli O127:H6 str. E2348/69 7061045 YP_002328555.1 CDS E2348C_0992 NC_011601.1 1049089 1049457 R single-stranded DNA binding protein complement(1049089..1049457) Escherichia coli O127:H6 str. E2348/69 7061046 YP_002328556.1 CDS E2348C_0993 NC_011601.1 1049608 1050078 R hypothetical protein complement(1049608..1050078) Escherichia coli O127:H6 str. E2348/69 7061047 YP_002328557.1 CDS E2348C_0994 NC_011601.1 1050137 1050409 R antitermination protein complement(1050137..1050409) Escherichia coli O127:H6 str. E2348/69 7061048 YP_002328558.1 CDS E2348C_0995 NC_011601.1 1050848 1051690 R DNA-damage-inducible protein complement(1050848..1051690) Escherichia coli O127:H6 str. E2348/69 7061049 YP_002328559.1 CDS E2348C_0996 NC_011601.1 1051771 1052424 R repressor protein complement(1051771..1052424) Escherichia coli O127:H6 str. E2348/69 7061050 YP_002328560.1 CDS E2348C_0997 NC_011601.1 1052541 1052756 D antirepressor protein 1052541..1052756 Escherichia coli O127:H6 str. E2348/69 7061051 YP_002328561.1 CDS E2348C_0998 NC_011601.1 1052898 1053194 D regulatory protein 1052898..1053194 Escherichia coli O127:H6 str. E2348/69 7061052 YP_002328562.1 CDS E2348C_0999 NC_011601.1 1053227 1054126 D replication protein 1053227..1054126 Escherichia coli O127:H6 str. E2348/69 7061053 YP_002328563.1 CDS E2348C_1000 NC_011601.1 1054123 1054824 D replication protein 1054123..1054824 Escherichia coli O127:H6 str. E2348/69 7061054 YP_002328564.1 CDS E2348C_1001 NC_011601.1 1054821 1055111 D exclusion protein 1054821..1055111 Escherichia coli O127:H6 str. E2348/69 7061055 YP_002328565.1 CDS E2348C_1002 NC_011601.1 1055184 1055510 D hypothetical protein 1055184..1055510 Escherichia coli O127:H6 str. E2348/69 7061056 YP_002328566.1 CDS E2348C_1003 NC_011601.1 1055533 1055979 D protein NinB 1055533..1055979 Escherichia coli O127:H6 str. E2348/69 7061057 YP_002328567.1 CDS E2348C_1004 NC_011601.1 1055976 1056503 D DNA methylase 1055976..1056503 Escherichia coli O127:H6 str. E2348/69 7061058 YP_002328568.1 CDS E2348C_1005 NC_011601.1 1056500 1056682 D protein NinE 1056500..1056682 Escherichia coli O127:H6 str. E2348/69 7061059 YP_002328569.1 CDS E2348C_1006 NC_011601.1 1056679 1056849 D protein NinF 1056679..1056849 Escherichia coli O127:H6 str. E2348/69 7061060 YP_002328570.1 CDS E2348C_1007 NC_011601.1 1056842 1057564 D DNA-binding protein 1056842..1057564 Escherichia coli O127:H6 str. E2348/69 7061061 YP_002328571.1 CDS E2348C_1008 NC_011601.1 1057564 1057854 D hypothetical protein 1057564..1057854 Escherichia coli O127:H6 str. E2348/69 7061062 YP_002328572.1 CDS E2348C_1009 NC_011601.1 1057851 1058213 D crossover junction endodeoxyribonuclease 1057851..1058213 Escherichia coli O127:H6 str. E2348/69 7061063 YP_002328573.1 CDS E2348C_1010 NC_011601.1 1058210 1058344 D hypothetical protein 1058210..1058344 Escherichia coli O127:H6 str. E2348/69 7061064 YP_002328574.1 CDS E2348C_1011 NC_011601.1 1058356 1058979 D late gene regulator 1058356..1058979 Escherichia coli O127:H6 str. E2348/69 7061065 YP_002328575.1 CDS E2348C_1012 NC_011601.1 1059259 1059975 D membrane protein 1059259..1059975 Escherichia coli O127:H6 str. E2348/69 7061066 YP_002328576.1 CDS E2348C_1013 NC_011601.1 1060300 1060698 R hypothetical protein complement(1060300..1060698) Escherichia coli O127:H6 str. E2348/69 7061067 YP_002328577.1 CDS E2348C_1014 NC_011601.1 1060841 1061056 D holin protein 1060841..1061056 Escherichia coli O127:H6 str. E2348/69 7061068 YP_002328578.1 CDS E2348C_1015 NC_011601.1 1061056 1061553 D endolysin 1061056..1061553 Escherichia coli O127:H6 str. E2348/69 7061069 YP_002328579.1 CDS E2348C_1016 NC_011601.1 1061550 1062017 D endopeptidase 1061550..1062017 Escherichia coli O127:H6 str. E2348/69 7061070 YP_002328580.1 CDS E2348C_1017 NC_011601.1 1061770 1061976 D lipoprotein precursor 1061770..1061976 Escherichia coli O127:H6 str. E2348/69 7061071 YP_002328581.1 CDS E2348C_1018 NC_011601.1 1062216 1062740 D hypothetical protein 1062216..1062740 Escherichia coli O127:H6 str. E2348/69 7061072 YP_002328582.1 CDS E2348C_1019 NC_011601.1 1063348 1063842 D hypothetical protein 1063348..1063842 Escherichia coli O127:H6 str. E2348/69 7061073 YP_002328583.1 CDS E2348C_1020 NC_011601.1 1063842 1065944 D terminase large subunit 1063842..1065944 Escherichia coli O127:H6 str. E2348/69 7061074 YP_002328584.1 CDS E2348C_1021 NC_011601.1 1065941 1066153 D hypothetical protein 1065941..1066153 Escherichia coli O127:H6 str. E2348/69 7061075 YP_002328585.1 CDS E2348C_1022 NC_011601.1 1066153 1067661 D portal protein 1066153..1067661 Escherichia coli O127:H6 str. E2348/69 7061076 YP_002328586.1 CDS E2348C_1023 NC_011601.1 1067543 1069633 D protease/scaffold protein 1067543..1069633 Escherichia coli O127:H6 str. E2348/69 7061077 YP_002328587.1 CDS E2348C_1024 NC_011601.1 1069720 1070043 D hypothetical protein 1069720..1070043 Escherichia coli O127:H6 str. E2348/69 7061078 YP_002328588.1 CDS E2348C_1025 NC_011601.1 1070036 1070311 D hypothetical protein 1070036..1070311 Escherichia coli O127:H6 str. E2348/69 7061079 YP_002328589.1 CDS E2348C_1026 NC_011601.1 1070323 1070901 D minor tail protein 1070323..1070901 Escherichia coli O127:H6 str. E2348/69 7061080 YP_002328590.1 CDS E2348C_1027 NC_011601.1 1070898 1071299 D minor tail protein 1070898..1071299 Escherichia coli O127:H6 str. E2348/69 7061081 YP_002328591.1 CDS E2348C_1028 NC_011601.1 1071310 1072053 D major tail protein 1071310..1072053 Escherichia coli O127:H6 str. E2348/69 7061082 YP_002328592.1 CDS E2348C_1029 NC_011601.1 1072114 1072500 D minor tail protein 1072114..1072500 Escherichia coli O127:H6 str. E2348/69 7061083 YP_002328593.1 CDS E2348C_1030 NC_011601.1 1072509 1072838 D minor tail protein 1072509..1072838 Escherichia coli O127:H6 str. E2348/69 7061084 YP_002328594.1 CDS E2348C_1032 NC_011601.1 1075865 1076194 D minor tail protein 1075865..1076194 Escherichia coli O127:H6 str. E2348/69 7061086 YP_002328595.1 CDS E2348C_1033 NC_011601.1 1076204 1076902 D minor tail protein 1076204..1076902 Escherichia coli O127:H6 str. E2348/69 7061087 YP_002328596.1 CDS E2348C_1034 NC_011601.1 1076907 1077650 D tail assembly protein 1076907..1077650 Escherichia coli O127:H6 str. E2348/69 7061088 YP_002328597.1 CDS E2348C_1035 NC_011601.1 1077548 1078195 D tail assembly protein 1077548..1078195 Escherichia coli O127:H6 str. E2348/69 7061089 YP_002328598.1 CDS E2348C_1037 NC_011601.1 1082040 1082639 D outer membrane precursor Lom 1082040..1082639 Escherichia coli O127:H6 str. E2348/69 7061091 YP_002328599.1 CDS E2348C_1038 NC_011601.1 1082704 1084017 D side tail fiber protein 1082704..1084017 Escherichia coli O127:H6 str. E2348/69 7061092 YP_002328600.1 CDS E2348C_1039 NC_011601.1 1084019 1084288 D hypothetical protein 1084019..1084288 Escherichia coli O127:H6 str. E2348/69 7061093 YP_002328601.1 CDS E2348C_1040 NC_011601.1 1084403 1084981 D T3SS secreted effector NleI/NleG-like protein 1084403..1084981 Escherichia coli O127:H6 str. E2348/69 7061094 YP_002328602.1 CDS E2348C_1041 NC_011601.1 1085343 1086323 D T3SS effector-like protein NleB-like protein 1085343..1086323 Escherichia coli O127:H6 str. E2348/69 7061095 YP_002328603.1 CDS E2348C_1042 NC_011601.1 1086384 1087376 D T3SS secreted effector NleC-like protein 1086384..1087376 Escherichia coli O127:H6 str. E2348/69 7061096 YP_002328604.1 CDS E2348C_1044 NC_011601.1 1087845 1088543 D T3SS secreted effector NleD-like protein 1087845..1088543 Escherichia coli O127:H6 str. E2348/69 7064968 YP_002328605.1 CDS torT NC_011601.1 1089018 1090046 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1089018..1090046 Escherichia coli O127:H6 str. E2348/69 7064684 YP_002328606.1 CDS torR NC_011601.1 1090019 1090711 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1090019..1090711) Escherichia coli O127:H6 str. E2348/69 7062226 YP_002328607.1 CDS torC NC_011601.1 1090841 1092013 D trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1090841..1092013 Escherichia coli O127:H6 str. E2348/69 7062224 YP_002328608.1 CDS torA NC_011601.1 1092013 1094559 D trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1092013..1094559 Escherichia coli O127:H6 str. E2348/69 7062221 YP_002328609.1 CDS torD NC_011601.1 1094556 1095155 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1094556..1095155 Escherichia coli O127:H6 str. E2348/69 7062220 YP_002328610.1 CDS cbpM NC_011601.1 1095511 1095816 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1095511..1095816) Escherichia coli O127:H6 str. E2348/69 7062222 YP_002328611.1 CDS cbpA NC_011601.1 1095816 1096736 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1095816..1096736) Escherichia coli O127:H6 str. E2348/69 7064328 YP_002328612.1 CDS agp NC_011601.1 1097271 1098512 D glucose-1-phosphatase/inositol phosphatase 1097271..1098512 Escherichia coli O127:H6 str. E2348/69 7064327 YP_002328613.1 CDS E2348C_1053 NC_011601.1 1098701 1100074 D transposase of ISEc13 1098701..1100074 Escherichia coli O127:H6 str. E2348/69 7064969 YP_002328614.1 CDS yccJ NC_011601.1 1100109 1100336 R hypothetical protein complement(1100109..1100336) Escherichia coli O127:H6 str. E2348/69 7064685 YP_002328615.1 CDS wrbA NC_011601.1 1100357 1100953 R stationary phase that binds TrpR repressor; TrpR binding protein WrbA complement(1100357..1100953) Escherichia coli O127:H6 str. E2348/69 7061427 YP_002328616.1 CDS ymdF NC_011601.1 1101326 1101499 D hypothetical protein 1101326..1101499 Escherichia coli O127:H6 str. E2348/69 7064845 YP_002328617.1 CDS rutG NC_011601.1 1101582 1102910 R transporter complement(1101582..1102910) Escherichia coli O127:H6 str. E2348/69 7062025 YP_002328618.1 CDS rutF NC_011601.1 1102931 1103425 R oxidoreductase, flavin: NADH component complement(1102931..1103425) Escherichia coli O127:H6 str. E2348/69 7064586 YP_002328619.1 CDS rutE NC_011601.1 1103436 1104026 R hypothetical protein complement(1103436..1104026) Escherichia coli O127:H6 str. E2348/69 7064585 YP_002328620.1 CDS rutD NC_011601.1 1104036 1104836 R hydrolase complement(1104036..1104836) Escherichia coli O127:H6 str. E2348/69 7064584 YP_002328621.1 CDS rutC NC_011601.1 1104844 1105230 R hypothetical protein complement(1104844..1105230) Escherichia coli O127:H6 str. E2348/69 7064583 YP_002328622.1 CDS rutB NC_011601.1 1105242 1105934 R hypothetical protein complement(1105242..1105934) Escherichia coli O127:H6 str. E2348/69 7064582 YP_002328623.1 CDS rutA NC_011601.1 1105934 1107025 R monooxygenase complement(1105934..1107025) Escherichia coli O127:H6 str. E2348/69 7064581 YP_002328624.1 CDS rutR NC_011601.1 1107313 1107951 D DNA-binding transcriptional regulator 1107313..1107951 Escherichia coli O127:H6 str. E2348/69 7064580 YP_002328625.1 CDS putA NC_011601.1 1107991 1111953 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1107991..1111953) Escherichia coli O127:H6 str. E2348/69 7064587 YP_002328626.1 CDS putP NC_011601.1 1112376 1113884 D proline: sodium symporter 1112376..1113884 Escherichia coli O127:H6 str. E2348/69 7063925 YP_002328627.1 CDS efeU NC_011601.1 1114104 1114934 D high-affinity Fe2+/Pb2+ permease 1114104..1114934 Escherichia coli O127:H6 str. E2348/69 7063926 YP_002328628.1 CDS ycdO NC_011601.1 1114992 1116119 D hypothetical protein 1114992..1116119 Escherichia coli O127:H6 str. E2348/69 7063839 YP_002328629.1 CDS ycdB NC_011601.1 1116125 1117396 D hypothetical protein 1116125..1117396 Escherichia coli O127:H6 str. E2348/69 7061437 YP_002328630.1 CDS phoH NC_011601.1 1117747 1118811 D hypothetical protein 1117747..1118811 Escherichia coli O127:H6 str. E2348/69 7061436 YP_002328631.1 CDS E2348C_1071 NC_011601.1 1119374 1120060 D hypothetical protein 1119374..1120060 Escherichia coli O127:H6 str. E2348/69 7060745 YP_002328632.1 CDS E2348C_1072 NC_011601.1 1120326 1121543 D integrase 1120326..1121543 Escherichia coli O127:H6 str. E2348/69 7064956 YP_002328633.1 CDS E2348C_1073 NC_011601.1 1121713 1123242 R hypothetical protein complement(1121713..1123242) Escherichia coli O127:H6 str. E2348/69 7064687 YP_002328634.1 CDS E2348C_1074 NC_011601.1 1123602 1125437 D hypothetical protein 1123602..1125437 Escherichia coli O127:H6 str. E2348/69 7064688 YP_002328635.1 CDS E2348C_1075 NC_011601.1 1126812 1127375 D hypothetical protein 1126812..1127375 Escherichia coli O127:H6 str. E2348/69 7064689 YP_002328636.1 CDS E2348C_1078 NC_011601.1 1129032 1129571 R hypothetical protein complement(1129032..1129571) Escherichia coli O127:H6 str. E2348/69 7064690 YP_002328637.1 CDS E2348C_1079 NC_011601.1 1129858 1137732 R Efa1/LifA-like protein complement(1129858..1137732) Escherichia coli O127:H6 str. E2348/69 7064691 YP_002328638.1 CDS E2348C_1080 NC_011601.1 1138203 1138709 R T3SS secreted effector NleE-like protein with internal deletion of 56 aa complement(1138203..1138709) Escherichia coli O127:H6 str. E2348/69 7064692 YP_002328639.1 CDS E2348C_1084 NC_011601.1 1144298 1144840 D transposase 1144298..1144840 Escherichia coli O127:H6 str. E2348/69 7064974 YP_002328640.1 CDS E2348C_1085 NC_011601.1 1144892 1145218 D transposase Orf1 of IS629 1144892..1145218 Escherichia coli O127:H6 str. E2348/69 7064975 YP_002328641.1 CDS E2348C_1086 NC_011601.1 1145215 1146105 D transposase Orf2 of IS629 1145215..1146105 Escherichia coli O127:H6 str. E2348/69 7064694 YP_002328642.1 CDS E2348C_1088 NC_011601.1 1147639 1148661 D transposase Orf1 of IS100 1147639..1148661 Escherichia coli O127:H6 str. E2348/69 7064977 YP_002328643.1 CDS E2348C_1089 NC_011601.1 1148661 1149440 D transposase/IS protein 1148661..1149440 Escherichia coli O127:H6 str. E2348/69 7064695 YP_002328644.1 CDS E2348C_1090 NC_011601.1 1150268 1150984 R hypothetical protein complement(1150268..1150984) Escherichia coli O127:H6 str. E2348/69 7064978 YP_002328645.1 CDS E2348C_1091 NC_011601.1 1150984 1154079 R HsdR family type I site-specific deoxyribonuclease complement(1150984..1154079) Escherichia coli O127:H6 str. E2348/69 7064696 YP_002328646.1 CDS E2348C_1092 NC_011601.1 1154098 1155126 R hypothetical protein complement(1154098..1155126) Escherichia coli O127:H6 str. E2348/69 7064697 YP_002328647.1 CDS E2348C_1093 NC_011601.1 1155162 1155818 R hypothetical protein complement(1155162..1155818) Escherichia coli O127:H6 str. E2348/69 7064698 YP_002328648.1 CDS E2348C_1094 NC_011601.1 1155830 1157179 R type I restriction-modification enzyme, S subunit complement(1155830..1157179) Escherichia coli O127:H6 str. E2348/69 7064699 YP_002328649.1 CDS E2348C_1095 NC_011601.1 1157191 1159629 R type I restriction-modification enzyme, M subunit complement(1157191..1159629) Escherichia coli O127:H6 str. E2348/69 7064700 YP_002328650.1 CDS E2348C_1096 NC_011601.1 1159669 1159908 R hypothetical protein complement(1159669..1159908) Escherichia coli O127:H6 str. E2348/69 7064701 YP_002328651.1 CDS E2348C_1097 NC_011601.1 1160137 1160445 R hypothetical protein complement(1160137..1160445) Escherichia coli O127:H6 str. E2348/69 7064702 YP_002328652.1 CDS E2348C_1098 NC_011601.1 1161060 1161428 D hypothetical protein 1161060..1161428 Escherichia coli O127:H6 str. E2348/69 7064703 YP_002328653.1 CDS E2348C_1099 NC_011601.1 1161498 1161884 D hypothetical protein 1161498..1161884 Escherichia coli O127:H6 str. E2348/69 7064704 YP_002328654.1 CDS E2348C_1100 NC_011601.1 1162034 1162303 R hypothetical protein complement(1162034..1162303) Escherichia coli O127:H6 str. E2348/69 7064705 YP_002328655.1 CDS E2348C_1101 NC_011601.1 1162899 1163765 R transposase Orf2 of ISEc17 complement(1162899..1163765) Escherichia coli O127:H6 str. E2348/69 7064979 YP_002328656.1 CDS E2348C_1102 NC_011601.1 1163762 1164061 R transposase Orf1 of ISEc17 complement(1163762..1164061) Escherichia coli O127:H6 str. E2348/69 7064706 YP_002328657.1 CDS E2348C_1103 NC_011601.1 1164464 1165867 D transposase Orf3 of IS66 family IS element 1164464..1165867 Escherichia coli O127:H6 str. E2348/69 7064980 YP_002328658.1 CDS E2348C_1105 NC_011601.1 1167047 1167937 R transposase Orf2 of IS629 complement(1167047..1167937) Escherichia coli O127:H6 str. E2348/69 7064982 YP_002328659.1 CDS E2348C_1106 NC_011601.1 1167934 1168260 R transposase Orf1 of IS629 complement(1167934..1168260) Escherichia coli O127:H6 str. E2348/69 7064707 YP_002328660.1 CDS E2348C_1110 NC_011601.1 1171483 1173867 D hypothetical protein 1171483..1173867 Escherichia coli O127:H6 str. E2348/69 7064710 YP_002328661.1 CDS E2348C_1111 NC_011601.1 1173864 1174769 D hypothetical protein 1173864..1174769 Escherichia coli O127:H6 str. E2348/69 7064711 YP_002328662.1 CDS E2348C_1112 NC_011601.1 1174766 1175836 D hypothetical protein 1174766..1175836 Escherichia coli O127:H6 str. E2348/69 7064712 YP_002328663.1 CDS E2348C_1113 NC_011601.1 1175941 1176105 R hypothetical protein complement(1175941..1176105) Escherichia coli O127:H6 str. E2348/69 7064713 YP_002328664.1 CDS E2348C_1114 NC_011601.1 1176176 1176994 D hypothetical protein 1176176..1176994 Escherichia coli O127:H6 str. E2348/69 7064714 YP_002328665.1 CDS E2348C_1115 NC_011601.1 1177085 1177570 D hypothetical protein 1177085..1177570 Escherichia coli O127:H6 str. E2348/69 7064715 YP_002328666.1 CDS E2348C_1116 NC_011601.1 1177586 1178062 D hypothetical protein 1177586..1178062 Escherichia coli O127:H6 str. E2348/69 7064716 YP_002328667.1 CDS E2348C_1117 NC_011601.1 1178125 1178346 D hypothetical protein 1178125..1178346 Escherichia coli O127:H6 str. E2348/69 7064717 YP_002328668.1 CDS E2348C_1118 NC_011601.1 1178509 1178883 D hypothetical protein 1178509..1178883 Escherichia coli O127:H6 str. E2348/69 7064718 YP_002328669.1 CDS E2348C_1119 NC_011601.1 1178930 1179304 D hypothetical protein 1178930..1179304 Escherichia coli O127:H6 str. E2348/69 7064719 YP_002328670.1 CDS E2348C_1120 NC_011601.1 1179301 1179792 D hypothetical protein 1179301..1179792 Escherichia coli O127:H6 str. E2348/69 7064720 YP_002328671.1 CDS E2348C_1121 NC_011601.1 1179804 1180001 D hypothetical protein 1179804..1180001 Escherichia coli O127:H6 str. E2348/69 7064721 YP_002328672.1 CDS E2348C_1122 NC_011601.1 1180086 1180928 D hypothetical protein 1180086..1180928 Escherichia coli O127:H6 str. E2348/69 7064722 YP_002328673.1 CDS ghrA NC_011601.1 1181398 1182336 D 2-ketoacid reductase 1181398..1182336 Escherichia coli O127:H6 str. E2348/69 7062707 YP_002328674.1 CDS ycdX NC_011601.1 1182391 1183128 D hydrolase 1182391..1183128 Escherichia coli O127:H6 str. E2348/69 7061654 YP_002328675.1 CDS ycdY NC_011601.1 1183152 1183706 D hypothetical protein 1183152..1183706 Escherichia coli O127:H6 str. E2348/69 7061438 YP_002328676.1 CDS ycdZ NC_011601.1 1183778 1184299 D hypothetical protein 1183778..1184299 Escherichia coli O127:H6 str. E2348/69 7061439 YP_002328677.1 CDS csgG NC_011601.1 1184363 1185196 R outer membrane lipoprotein complement(1184363..1185196) Escherichia coli O127:H6 str. E2348/69 7061440 YP_002328678.1 CDS csgF NC_011601.1 1185223 1185639 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1185223..1185639) Escherichia coli O127:H6 str. E2348/69 7062856 YP_002328679.1 CDS csgE NC_011601.1 1185664 1186053 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1185664..1186053) Escherichia coli O127:H6 str. E2348/69 7062855 YP_002328680.1 CDS csgD NC_011601.1 1186058 1186708 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1186058..1186708) Escherichia coli O127:H6 str. E2348/69 7062854 YP_002328681.1 CDS E2348C_1131 NC_011601.1 1187120 1187359 R hypothetical protein complement(1187120..1187359) Escherichia coli O127:H6 str. E2348/69 7062853 YP_002328682.1 CDS csgB NC_011601.1 1187462 1187917 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1187462..1187917 Escherichia coli O127:H6 str. E2348/69 7064724 YP_002328683.1 CDS csgA NC_011601.1 1187958 1188413 D cryptic curlin major subunit 1187958..1188413 Escherichia coli O127:H6 str. E2348/69 7062851 YP_002328684.1 CDS csgC NC_011601.1 1188472 1188804 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1188472..1188804 Escherichia coli O127:H6 str. E2348/69 7062850 YP_002328685.1 CDS ymdA NC_011601.1 1188925 1189236 D hypothetical protein 1188925..1189236 Escherichia coli O127:H6 str. E2348/69 7062852 YP_002328686.1 CDS ymdB NC_011601.1 1189331 1189864 D hypothetical protein 1189331..1189864 Escherichia coli O127:H6 str. E2348/69 7062022 YP_002328687.1 CDS ymdC NC_011601.1 1189866 1191287 D hydrolase 1189866..1191287 Escherichia coli O127:H6 str. E2348/69 7062023 YP_002328688.1 CDS mdoC NC_011601.1 1191295 1192452 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1191295..1192452) Escherichia coli O127:H6 str. E2348/69 7062024 YP_002328689.1 CDS mdoG NC_011601.1 1192846 1194381 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1192846..1194381 Escherichia coli O127:H6 str. E2348/69 7065302 YP_002328690.1 CDS mdoH NC_011601.1 1194374 1196917 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1194374..1196917 Escherichia coli O127:H6 str. E2348/69 7065304 YP_002328691.1 CDS yceK NC_011601.1 1197090 1197317 D hypothetical protein 1197090..1197317 Escherichia coli O127:H6 str. E2348/69 7065305 YP_002328692.1 CDS msyB NC_011601.1 1197318 1197692 R hypothetical protein complement(1197318..1197692) Escherichia coli O127:H6 str. E2348/69 7061449 YP_002328693.1 CDS mdtG NC_011601.1 1197775 1199001 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1197775..1199001) Escherichia coli O127:H6 str. E2348/69 7060876 YP_002328694.1 CDS lpxL NC_011601.1 1199173 1200093 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1199173..1200093) Escherichia coli O127:H6 str. E2348/69 7065312 YP_002328695.1 CDS yceA NC_011601.1 1200318 1201370 D hypothetical protein 1200318..1201370 Escherichia coli O127:H6 str. E2348/69 7061578 YP_002328696.1 CDS yceI NC_011601.1 1201412 1201987 R hypothetical protein complement(1201412..1201987) Escherichia coli O127:H6 str. E2348/69 7061441 YP_002328697.1 CDS yceJ NC_011601.1 1201991 1202557 R cytochrome b561 complement(1201991..1202557) Escherichia coli O127:H6 str. E2348/69 7061447 YP_002328698.1 CDS yceO NC_011601.1 1202819 1202932 R hypothetical protein complement(1202819..1202932) Escherichia coli O127:H6 str. E2348/69 7061448 YP_002328699.1 CDS solA NC_011601.1 1202980 1204098 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1202980..1204098) Escherichia coli O127:H6 str. E2348/69 7061452 YP_002328700.1 CDS bssS NC_011601.1 1204213 1204467 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1204213..1204467) Escherichia coli O127:H6 str. E2348/69 7062737 YP_002328701.1 CDS dinI NC_011601.1 1204757 1205002 R DNA damage-inducible protein I complement(1204757..1205002) Escherichia coli O127:H6 str. E2348/69 7062533 YP_002328702.1 CDS pyrC NC_011601.1 1205076 1206122 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1205076..1206122) Escherichia coli O127:H6 str. E2348/69 7065032 YP_002328703.1 CDS yceB NC_011601.1 1206228 1206788 R hypothetical protein complement(1206228..1206788) Escherichia coli O127:H6 str. E2348/69 7063930 YP_002328704.1 CDS grxB NC_011601.1 1206922 1207569 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1206922..1207569) Escherichia coli O127:H6 str. E2348/69 7061442 YP_002328705.1 CDS mdtH NC_011601.1 1207633 1208841 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1207633..1208841) Escherichia coli O127:H6 str. E2348/69 7064247 YP_002328706.1 CDS rimJ NC_011601.1 1209077 1209661 D ribosomal-protein-S5-alanine N-acetyltransferase 1209077..1209661 Escherichia coli O127:H6 str. E2348/69 7065313 YP_002328707.1 CDS yceH NC_011601.1 1209672 1210319 D hypothetical protein 1209672..1210319 Escherichia coli O127:H6 str. E2348/69 7060828 YP_002328708.1 CDS yceM NC_011601.1 1210321 1211244 D oxidoreductase with NAD(P)-binding Rossmann-fold domain 1210321..1211244 Escherichia coli O127:H6 str. E2348/69 7061446 YP_002328709.1 CDS yceN NC_011601.1 1211354 1212889 D hypothetical protein 1211354..1212889 Escherichia coli O127:H6 str. E2348/69 7061450 YP_002328710.1 CDS flgN NC_011601.1 1212929 1213345 R export chaperone for FlgK and FlgL complement(1212929..1213345) Escherichia coli O127:H6 str. E2348/69 7061451 YP_002328711.1 CDS flgM NC_011601.1 1213350 1213643 R regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1213350..1213643) Escherichia coli O127:H6 str. E2348/69 7061907 YP_002328712.1 CDS flgA NC_011601.1 1213719 1214378 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1213719..1214378) Escherichia coli O127:H6 str. E2348/69 7061906 YP_002328713.1 CDS flgB NC_011601.1 1214533 1214949 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1214533..1214949 Escherichia coli O127:H6 str. E2348/69 7062138 YP_002328714.1 CDS flgC NC_011601.1 1214953 1215357 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1214953..1215357 Escherichia coli O127:H6 str. E2348/69 7062139 YP_002328715.1 CDS flgD NC_011601.1 1215369 1216064 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1215369..1216064 Escherichia coli O127:H6 str. E2348/69 7061819 YP_002328716.1 CDS flgE NC_011601.1 1216089 1217294 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1216089..1217294 Escherichia coli O127:H6 str. E2348/69 7061897 YP_002328717.1 CDS flgF NC_011601.1 1217314 1218069 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1217314..1218069 Escherichia coli O127:H6 str. E2348/69 7061898 YP_002328718.1 CDS flgG NC_011601.1 1218241 1219023 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1218241..1219023 Escherichia coli O127:H6 str. E2348/69 7061899 YP_002328719.1 CDS flgH NC_011601.1 1219076 1219774 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1219076..1219774 Escherichia coli O127:H6 str. E2348/69 7061900 YP_002328720.1 CDS flgI NC_011601.1 1219786 1220883 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1219786..1220883 Escherichia coli O127:H6 str. E2348/69 7061901 YP_002328721.1 CDS flgJ NC_011601.1 1220883 1221824 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1220883..1221824 Escherichia coli O127:H6 str. E2348/69 7061902 YP_002328722.1 CDS flgK NC_011601.1 1221890 1223533 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1221890..1223533 Escherichia coli O127:H6 str. E2348/69 7061903 YP_002328723.1 CDS flgL NC_011601.1 1223545 1224498 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1223545..1224498 Escherichia coli O127:H6 str. E2348/69 7061904 YP_002328724.1 CDS E2348C_1174 NC_011601.1 1224593 1225087 R acetyltransferase complement(1224593..1225087) Escherichia coli O127:H6 str. E2348/69 7061905 YP_002328725.1 CDS E2348C_1175 NC_011601.1 1225084 1225377 R hypothetical protein complement(1225084..1225377) Escherichia coli O127:H6 str. E2348/69 7064725 YP_002328726.1 CDS rne NC_011601.1 1225511 1228696 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1225511..1228696) Escherichia coli O127:H6 str. E2348/69 7064726 YP_002328727.1 CDS yceQ NC_011601.1 1228831 1229151 D hypothetical protein 1228831..1229151 Escherichia coli O127:H6 str. E2348/69 7060851 YP_002328728.1 CDS rluC NC_011601.1 1229269 1230228 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1229269..1230228 Escherichia coli O127:H6 str. E2348/69 7061453 YP_002328729.1 CDS yceF NC_011601.1 1230340 1230924 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1230340..1230924) Escherichia coli O127:H6 str. E2348/69 7060840 YP_002328730.1 CDS yceD NC_011601.1 1231123 1231644 D hypothetical protein 1231123..1231644 Escherichia coli O127:H6 str. E2348/69 7061325 YP_002328731.1 CDS rpmF NC_011601.1 1231696 1231869 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1231696..1231869 Escherichia coli O127:H6 str. E2348/69 7061443 YP_002328732.1 CDS plsX NC_011601.1 1231980 1233020 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1231980..1233020 Escherichia coli O127:H6 str. E2348/69 7061858 YP_002328733.1 CDS fabH NC_011601.1 1233088 1234041 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1233088..1234041 Escherichia coli O127:H6 str. E2348/69 7060758 YP_002328734.1 CDS fabD NC_011601.1 1234057 1234986 D malonyl-CoA-[acyl-carrier-protein] transacylase 1234057..1234986 Escherichia coli O127:H6 str. E2348/69 7062067 YP_002328735.1 CDS fabG NC_011601.1 1234999 1235733 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1234999..1235733 Escherichia coli O127:H6 str. E2348/69 7062064 YP_002328736.1 CDS acpP NC_011601.1 1235944 1236180 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1235944..1236180 Escherichia coli O127:H6 str. E2348/69 7062066 YP_002328737.1 CDS fabF NC_011601.1 1236268 1237509 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1236268..1237509 Escherichia coli O127:H6 str. E2348/69 7062393 YP_002328738.1 CDS pabC NC_011601.1 1237629 1238438 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1237629..1238438 Escherichia coli O127:H6 str. E2348/69 7062065 YP_002328739.1 CDS yceG NC_011601.1 1238441 1239463 D hypothetical protein 1238441..1239463 Escherichia coli O127:H6 str. E2348/69 7062902 YP_002328740.1 CDS tmk NC_011601.1 1239453 1240094 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1239453..1240094 Escherichia coli O127:H6 str. E2348/69 7061445 YP_002328741.1 CDS holB NC_011601.1 1240091 1241095 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1240091..1241095 Escherichia coli O127:H6 str. E2348/69 7061809 YP_002328742.1 CDS ycfH NC_011601.1 1241106 1241903 D metallodependent hydrolase 1241106..1241903 Escherichia coli O127:H6 str. E2348/69 7062172 YP_002328743.1 CDS ptsG NC_011601.1 1242197 1243630 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1242197..1243630 Escherichia coli O127:H6 str. E2348/69 7061455 YP_002328744.1 CDS fhuE NC_011601.1 1243690 1245879 R ferric-rhodotorulic acid outer membrane transporter complement(1243690..1245879) Escherichia coli O127:H6 str. E2348/69 7061338 YP_002328745.1 CDS hinT NC_011601.1 1246213 1246572 D purine nucleoside phosphoramidase 1246213..1246572 Escherichia coli O127:H6 str. E2348/69 7062115 YP_002328746.1 CDS ycfL NC_011601.1 1246575 1246952 D hypothetical protein 1246575..1246952 Escherichia coli O127:H6 str. E2348/69 7062140 YP_002328747.1 CDS ycfM NC_011601.1 1246966 1247607 D outer membrane lipoprotein 1246966..1247607 Escherichia coli O127:H6 str. E2348/69 7061457 YP_002328748.1 CDS thiK NC_011601.1 1247588 1248412 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1247588..1248412 Escherichia coli O127:H6 str. E2348/69 7061458 YP_002328749.1 CDS nagZ NC_011601.1 1248423 1249448 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1248423..1249448 Escherichia coli O127:H6 str. E2348/69 7061787 YP_002328750.1 CDS ycfP NC_011601.1 1249471 1250013 D hypothetical protein 1249471..1250013 Escherichia coli O127:H6 str. E2348/69 7060917 YP_002328751.1 CDS ndh NC_011601.1 1250412 1251716 D respiratory NADH dehydrogenase 2/cupricreductase 1250412..1251716 Escherichia coli O127:H6 str. E2348/69 7061459 YP_002328752.1 CDS ycfJ NC_011601.1 1251943 1252482 D hypothetical protein 1251943..1252482 Escherichia coli O127:H6 str. E2348/69 7065376 YP_002328753.1 CDS ycfQ NC_011601.1 1252544 1253176 R DNA-binding transcriptional regulator complement(1252544..1253176) Escherichia coli O127:H6 str. E2348/69 7061456 YP_002328754.1 CDS bhsA NC_011601.1 1253417 1253674 D outer membrane protein that influences biofilm formation 1253417..1253674 Escherichia coli O127:H6 str. E2348/69 7061460 YP_002328755.1 CDS ycfS NC_011601.1 1253756 1254718 R hypothetical protein complement(1253756..1254718) Escherichia coli O127:H6 str. E2348/69 7062519 YP_002328756.1 CDS mfd NC_011601.1 1254861 1258307 R transcription-repair coupling factor complement(1254861..1258307) Escherichia coli O127:H6 str. E2348/69 7061461 YP_002328757.1 CDS ycfT NC_011601.1 1258435 1259508 R hypothetical protein complement(1258435..1259508) Escherichia coli O127:H6 str. E2348/69 7063776 YP_002328758.1 CDS lolC NC_011601.1 1259769 1260968 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1259769..1260968 Escherichia coli O127:H6 str. E2348/69 7061462 YP_002328759.1 CDS lolD NC_011601.1 1260961 1261662 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1260961..1261662 Escherichia coli O127:H6 str. E2348/69 7061556 YP_002328760.1 CDS lolE NC_011601.1 1261662 1262906 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1261662..1262906 Escherichia coli O127:H6 str. E2348/69 7061557 YP_002328761.1 CDS nagK NC_011601.1 1262935 1263846 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1262935..1263846 Escherichia coli O127:H6 str. E2348/69 7061558 YP_002328762.1 CDS cobB NC_011601.1 1263862 1264683 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1263862..1264683 Escherichia coli O127:H6 str. E2348/69 7060916 YP_002328763.1 CDS ycfZ NC_011601.1 1264821 1265609 R hypothetical protein complement(1264821..1265609) Escherichia coli O127:H6 str. E2348/69 7062824 YP_002328764.1 CDS ymfA NC_011601.1 1265606 1266067 R hypothetical protein complement(1265606..1266067) Escherichia coli O127:H6 str. E2348/69 7061463 YP_002328765.1 CDS potD NC_011601.1 1266125 1267171 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1266125..1267171) Escherichia coli O127:H6 str. E2348/69 7062026 YP_002328766.1 CDS potC NC_011601.1 1267168 1267962 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1267168..1267962) Escherichia coli O127:H6 str. E2348/69 7060773 YP_002328767.1 CDS E2348C_1217 NC_011601.1 1268129 1269247 R integrase complement(1268129..1269247) Escherichia coli O127:H6 str. E2348/69 7061169 YP_002328768.1 CDS E2348C_1218 NC_011601.1 1269216 1269485 R excisionase complement(1269216..1269485) Escherichia coli O127:H6 str. E2348/69 7064727 YP_002328769.1 CDS E2348C_1219 NC_011601.1 1269547 1272018 R exonuclease complement(1269547..1272018) Escherichia coli O127:H6 str. E2348/69 7064728 YP_002328770.1 CDS E2348C_1221 NC_011601.1 1272299 1272487 R cell division inhibition protein DicB complement(1272299..1272487) Escherichia coli O127:H6 str. E2348/69 7064730 YP_002328771.1 CDS E2348C_1222 NC_011601.1 1272888 1273052 D hypothetical protein 1272888..1273052 Escherichia coli O127:H6 str. E2348/69 7065026 YP_002328772.1 CDS E2348C_1223 NC_011601.1 1273056 1273274 R hypothetical protein complement(1273056..1273274) Escherichia coli O127:H6 str. E2348/69 7064732 YP_002328773.1 CDS E2348C_1224 NC_011601.1 1273304 1273432 R hypothetical protein complement(1273304..1273432) Escherichia coli O127:H6 str. E2348/69 7064733 YP_002328774.1 CDS E2348C_1225 NC_011601.1 1273434 1273682 R hypothetical protein complement(1273434..1273682) Escherichia coli O127:H6 str. E2348/69 7064734 YP_002328775.1 CDS E2348C_1226 NC_011601.1 1273781 1274188 R The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA complement(1273781..1274188) Escherichia coli O127:H6 str. E2348/69 7064735 YP_002328776.1 CDS E2348C_1227 NC_011601.1 1274266 1274493 D DNA-binding transcriptional regulator DicC 1274266..1274493 Escherichia coli O127:H6 str. E2348/69 7064736 YP_002328777.1 CDS E2348C_1228 NC_011601.1 1274477 1275028 D hypothetical protein 1274477..1275028 Escherichia coli O127:H6 str. E2348/69 7064737 YP_002328778.1 CDS E2348C_1229 NC_011601.1 1275000 1276040 D replication protein 1275000..1276040 Escherichia coli O127:H6 str. E2348/69 7064738 YP_002328779.1 CDS E2348C_1230 NC_011601.1 1275829 1276494 D replication protein 1275829..1276494 Escherichia coli O127:H6 str. E2348/69 7064739 YP_002328780.1 CDS E2348C_1231 NC_011601.1 1276601 1276801 D hypothetical protein 1276601..1276801 Escherichia coli O127:H6 str. E2348/69 7064740 YP_002328781.1 CDS E2348C_1232 NC_011601.1 1277241 1278083 D hypothetical protein 1277241..1278083 Escherichia coli O127:H6 str. E2348/69 7064741 YP_002328782.1 CDS E2348C_1234 NC_011601.1 1279122 1280495 D ATP-binding protein 1279122..1280495 Escherichia coli O127:H6 str. E2348/69 7064743 YP_002328783.1 CDS E2348C_1235 NC_011601.1 1280482 1281117 D HNH endonuclease 1280482..1281117 Escherichia coli O127:H6 str. E2348/69 7064744 YP_002328784.1 CDS E2348C_1236 NC_011601.1 1281372 1282460 R transposase complement(1281372..1282460) Escherichia coli O127:H6 str. E2348/69 7064745 YP_002328785.1 CDS E2348C_1238 NC_011601.1 1282907 1283155 D hypothetical protein 1282907..1283155 Escherichia coli O127:H6 str. E2348/69 7064747 YP_002328786.1 CDS E2348C_1239 NC_011601.1 1283222 1283500 D hypothetical protein 1283222..1283500 Escherichia coli O127:H6 str. E2348/69 7064748 YP_002328787.1 CDS E2348C_1240 NC_011601.1 1283502 1284560 D hypothetical protein 1283502..1284560 Escherichia coli O127:H6 str. E2348/69 7064749 YP_002328788.1 CDS E2348C_1241 NC_011601.1 1284561 1284926 D crossover junction endodeoxyribonuclease 1284561..1284926 Escherichia coli O127:H6 str. E2348/69 7064750 YP_002328789.1 CDS E2348C_1242 NC_011601.1 1284935 1285477 D hypothetical protein 1284935..1285477 Escherichia coli O127:H6 str. E2348/69 7064751 YP_002328790.1 CDS E2348C_1243 NC_011601.1 1285755 1285988 D hypothetical protein 1285755..1285988 Escherichia coli O127:H6 str. E2348/69 7064752 YP_002328791.1 CDS E2348C_1244 NC_011601.1 1286139 1287188 D DNA methylase 1286139..1287188 Escherichia coli O127:H6 str. E2348/69 7064753 YP_002328792.1 CDS E2348C_1245 NC_011601.1 1288384 1288719 R hypothetical protein complement(1288384..1288719) Escherichia coli O127:H6 str. E2348/69 7062248 YP_002328793.1 CDS E2348C_1246 NC_011601.1 1288980 1290830 D hypothetical protein 1288980..1290830 Escherichia coli O127:H6 str. E2348/69 7064755 YP_002328794.1 CDS E2348C_1247 NC_011601.1 1291265 1292638 D transposase of ISEc13 1291265..1292638 Escherichia coli O127:H6 str. E2348/69 7064984 YP_002328795.1 CDS E2348C_1248 NC_011601.1 1292776 1293234 D transposase of IS200C 1292776..1293234 Escherichia coli O127:H6 str. E2348/69 7064985 YP_002328796.1 CDS E2348C_1249 NC_011601.1 1293394 1293600 D holin protein 1293394..1293600 Escherichia coli O127:H6 str. E2348/69 7064756 YP_002328797.1 CDS E2348C_1250 NC_011601.1 1293600 1294097 D endolysin 1293600..1294097 Escherichia coli O127:H6 str. E2348/69 7064757 YP_002328798.1 CDS E2348C_1251 NC_011601.1 1294094 1294531 D endopeptidase 1294094..1294531 Escherichia coli O127:H6 str. E2348/69 7064758 YP_002328799.1 CDS E2348C_1252 NC_011601.1 1294293 1294478 D lipoprotein Rz1 1294293..1294478 Escherichia coli O127:H6 str. E2348/69 7064759 YP_002328800.1 CDS E2348C_1253 NC_011601.1 1295554 1295880 D TonB-like protein 1295554..1295880 Escherichia coli O127:H6 str. E2348/69 7064760 YP_002328801.1 CDS E2348C_1254 NC_011601.1 1296572 1297120 D terminase small subunit 1296572..1297120 Escherichia coli O127:H6 str. E2348/69 7064761 YP_002328802.1 CDS E2348C_1255 NC_011601.1 1297092 1299020 D terminase large subunit 1297092..1299020 Escherichia coli O127:H6 str. E2348/69 7064762 YP_002328803.1 CDS E2348C_1256 NC_011601.1 1299004 1299210 D head-tail joining protein 1299004..1299210 Escherichia coli O127:H6 str. E2348/69 7064763 YP_002328804.1 CDS E2348C_1257 NC_011601.1 1299207 1300799 D portal protein 1299207..1300799 Escherichia coli O127:H6 str. E2348/69 7064069 YP_002328805.1 CDS E2348C_1259 NC_011601.1 1301135 1301782 D tail assembly protein 1301135..1301782 Escherichia coli O127:H6 str. E2348/69 7064151 YP_002328806.1 CDS E2348C_1260 NC_011601.1 1301843 1305256 D host specificity protein 1301843..1305256 Escherichia coli O127:H6 str. E2348/69 7064152 YP_002328807.1 CDS E2348C_1261 NC_011601.1 1305326 1305925 D outer membrane precursor Lom 1305326..1305925 Escherichia coli O127:H6 str. E2348/69 7064153 YP_002328808.1 CDS E2348C_1262 NC_011601.1 1305990 1307303 D side tail fiber protein 1305990..1307303 Escherichia coli O127:H6 str. E2348/69 7064154 YP_002328809.1 CDS E2348C_1263 NC_011601.1 1307305 1307574 D hypothetical protein 1307305..1307574 Escherichia coli O127:H6 str. E2348/69 7064155 YP_002328810.1 CDS potB NC_011601.1 1308740 1309603 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1308740..1309603) Escherichia coli O127:H6 str. E2348/69 7064157 YP_002328811.1 CDS potA NC_011601.1 1309587 1310723 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1309587..1310723) Escherichia coli O127:H6 str. E2348/69 7060771 YP_002328812.1 CDS pepT NC_011601.1 1310973 1312199 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1310973..1312199 Escherichia coli O127:H6 str. E2348/69 7060770 YP_002328813.1 CDS ycfD NC_011601.1 1312248 1313369 R hypothetical protein complement(1312248..1313369) Escherichia coli O127:H6 str. E2348/69 7060705 YP_002328814.1 CDS phoQ NC_011601.1 1313445 1314905 R sensor protein PhoQ complement(1313445..1314905) Escherichia coli O127:H6 str. E2348/69 7061454 YP_002328815.1 CDS phoP NC_011601.1 1314905 1315576 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1314905..1315576) Escherichia coli O127:H6 str. E2348/69 7060747 YP_002328816.1 CDS purB NC_011601.1 1315746 1317116 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1315746..1317116) Escherichia coli O127:H6 str. E2348/69 7060746 YP_002328817.1 CDS hflD NC_011601.1 1317120 1317761 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1317120..1317761) Escherichia coli O127:H6 str. E2348/69 7063912 YP_002328818.1 CDS mnmA NC_011601.1 1317797 1318903 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1317797..1318903) Escherichia coli O127:H6 str. E2348/69 7064306 YP_002328819.1 CDS nudJ NC_011601.1 1318957 1319418 R bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase complement(1318957..1319418) Escherichia coli O127:H6 str. E2348/69 7063799 YP_002328820.1 CDS rluE NC_011601.1 1319428 1320081 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1319428..1320081) Escherichia coli O127:H6 str. E2348/69 7065434 YP_002328821.1 CDS icd NC_011601.1 1320254 1321504 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1320254..1321504 Escherichia coli O127:H6 str. E2348/69 7060842 YP_002328822.1 CDS ycgX NC_011601.1 1321766 1322170 R hypothetical protein complement(1321766..1322170) Escherichia coli O127:H6 str. E2348/69 7063517 YP_002328823.1 CDS ycgE NC_011601.1 1322391 1323122 R DNA-binding transcriptional regulator complement(1322391..1323122) Escherichia coli O127:H6 str. E2348/69 7061476 YP_002328824.1 CDS ycgF NC_011601.1 1323327 1324538 R FAD-binding phosphodiesterase complement(1323327..1324538) Escherichia coli O127:H6 str. E2348/69 7061465 YP_002328825.1 CDS ycgZ NC_011601.1 1324852 1325088 D hypothetical protein 1324852..1325088 Escherichia coli O127:H6 str. E2348/69 7061466 YP_002328826.1 CDS ymgA NC_011601.1 1325131 1325403 D hypothetical protein 1325131..1325403 Escherichia coli O127:H6 str. E2348/69 7061477 YP_002328827.1 CDS ymgB NC_011601.1 1325432 1325698 D hypothetical protein 1325432..1325698 Escherichia coli O127:H6 str. E2348/69 7062027 YP_002328828.1 CDS ymgC NC_011601.1 1325811 1326059 D hypothetical protein 1325811..1326059 Escherichia coli O127:H6 str. E2348/69 7062028 YP_002328829.1 CDS ymgF NC_011601.1 1327381 1327599 D hypothetical protein 1327381..1327599 Escherichia coli O127:H6 str. E2348/69 7061467 YP_002328830.1 CDS ymgD NC_011601.1 1329573 1329902 R hypothetical protein complement(1329573..1329902) Escherichia coli O127:H6 str. E2348/69 7061468 YP_002328831.1 CDS ymgG NC_011601.1 1329912 1330256 R hypothetical protein complement(1329912..1330256) Escherichia coli O127:H6 str. E2348/69 7062030 YP_002328832.1 CDS ymgI NC_011601.1 1330258 1330431 R hypothetical protein complement(1330258..1330431) Escherichia coli O127:H6 str. E2348/69 7062033 YP_002328833.1 CDS ymgJ NC_011601.1 1330532 1330717 D coserved protein 1330532..1330717 Escherichia coli O127:H6 str. E2348/69 7062034 YP_002328834.1 CDS minE NC_011601.1 1331546 1331812 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1331546..1331812) Escherichia coli O127:H6 str. E2348/69 7061469 YP_002328835.1 CDS minD NC_011601.1 1331816 1332628 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1331816..1332628) Escherichia coli O127:H6 str. E2348/69 7063790 YP_002328836.1 CDS minC NC_011601.1 1332652 1333347 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1332652..1333347) Escherichia coli O127:H6 str. E2348/69 7063789 YP_002328837.1 CDS ycgJ NC_011601.1 1333867 1334235 D hypothetical protein 1333867..1334235 Escherichia coli O127:H6 str. E2348/69 7063788 YP_002328838.1 CDS ycgK NC_011601.1 1334338 1334739 R hypothetical protein complement(1334338..1334739) Escherichia coli O127:H6 str. E2348/69 7061470 YP_002328839.1 CDS ycgL NC_011601.1 1334981 1335274 D hypothetical protein 1334981..1335274 Escherichia coli O127:H6 str. E2348/69 7061471 YP_002328840.1 CDS ycgM NC_011601.1 1335346 1336005 D hypothetical protein 1335346..1336005 Escherichia coli O127:H6 str. E2348/69 7061472 YP_002328841.1 CDS ycgN NC_011601.1 1336097 1336543 D hypothetical protein 1336097..1336543 Escherichia coli O127:H6 str. E2348/69 7061473 YP_002328842.1 CDS umuD NC_011601.1 1337336 1337755 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1337336..1337755 Escherichia coli O127:H6 str. E2348/69 7061144 YP_002328843.1 CDS umuC NC_011601.1 1337755 1339023 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1337755..1339023 Escherichia coli O127:H6 str. E2348/69 7062325 YP_002328844.1 CDS dsbB NC_011601.1 1339068 1339598 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1339068..1339598) Escherichia coli O127:H6 str. E2348/69 7062324 YP_002328845.1 CDS nhaB NC_011601.1 1339744 1341285 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1339744..1341285) Escherichia coli O127:H6 str. E2348/69 7065063 YP_002328846.1 CDS fadR NC_011601.1 1341507 1342226 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1341507..1342226 Escherichia coli O127:H6 str. E2348/69 7065388 YP_002328847.1 CDS ycgB NC_011601.1 1342277 1343809 R SpoVR family protein complement(1342277..1343809) Escherichia coli O127:H6 str. E2348/69 7062080 YP_002328848.1 CDS dadA NC_011601.1 1344139 1345437 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1344139..1345437 Escherichia coli O127:H6 str. E2348/69 7061464 YP_002328849.1 CDS dadX NC_011601.1 1345447 1346517 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1345447..1346517 Escherichia coli O127:H6 str. E2348/69 7065216 YP_002328850.1 CDS cvrA NC_011601.1 1346574 1348310 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1346574..1348310) Escherichia coli O127:H6 str. E2348/69 7065217 YP_002328851.1 CDS ldcA NC_011601.1 1348405 1349319 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1348405..1349319) Escherichia coli O127:H6 str. E2348/69 7065178 YP_002328852.1 CDS emtA NC_011601.1 1349419 1350030 D lytic murein endotransglycosylase E 1349419..1350030 Escherichia coli O127:H6 str. E2348/69 7061512 YP_002328853.1 CDS ycgR NC_011601.1 1350032 1350766 R protein involved in flagellar function complement(1350032..1350766) Escherichia coli O127:H6 str. E2348/69 7063849 YP_002328854.1 CDS ymgE NC_011601.1 1350967 1351221 D hypothetical protein 1350967..1351221 Escherichia coli O127:H6 str. E2348/69 7061475 YP_002328855.1 CDS E2348C_1315 NC_011601.1 1351271 1353241 R TonB dependent outer membrane receptor complement(1351271..1353241) Escherichia coli O127:H6 str. E2348/69 7062031 YP_002328856.1 CDS E2348C_1316 NC_011601.1 1353267 1354121 R involved in molybdenum transport; molybdenum transport protein ModD complement(1353267..1354121) Escherichia coli O127:H6 str. E2348/69 7064158 YP_002328857.1 CDS E2348C_1317 NC_011601.1 1354118 1354930 R hypothetical protein complement(1354118..1354930) Escherichia coli O127:H6 str. E2348/69 7064159 YP_002328858.1 CDS E2348C_1318 NC_011601.1 1354940 1355698 R ferric enterobactin transport ATP-binding protein complement(1354940..1355698) Escherichia coli O127:H6 str. E2348/69 7064160 YP_002328859.1 CDS E2348C_1319 NC_011601.1 1355695 1356675 R ABC transporter permease complement(1355695..1356675) Escherichia coli O127:H6 str. E2348/69 7064161 YP_002328860.1 CDS E2348C_1320 NC_011601.1 1356675 1357697 R ABC transporter ATP-binding protein complement(1356675..1357697) Escherichia coli O127:H6 str. E2348/69 7064162 YP_002328861.1 CDS treA NC_011601.1 1358034 1359731 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1358034..1359731) Escherichia coli O127:H6 str. E2348/69 7064163 YP_002328862.1 CDS dhaM NC_011601.1 1360051 1361469 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM complement(1360051..1361469) Escherichia coli O127:H6 str. E2348/69 7062233 YP_002328863.1 CDS dhaL NC_011601.1 1361480 1362112 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1361480..1362112) Escherichia coli O127:H6 str. E2348/69 7065023 YP_002328864.1 CDS dhaK NC_011601.1 1362123 1363193 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1362123..1363193) Escherichia coli O127:H6 str. E2348/69 7065022 YP_002328865.1 CDS dhaR NC_011601.1 1363423 1365342 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1363423..1365342 Escherichia coli O127:H6 str. E2348/69 7065021 YP_002328866.1 CDS ychF NC_011601.1 1365747 1366838 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1365747..1366838) Escherichia coli O127:H6 str. E2348/69 7065024 YP_002328867.1 CDS pth NC_011601.1 1366955 1367539 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1366955..1367539) Escherichia coli O127:H6 str. E2348/69 7061480 YP_002328868.1 CDS ychH NC_011601.1 1367817 1368095 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1367817..1368095 Escherichia coli O127:H6 str. E2348/69 7061334 YP_002328869.1 CDS ychM NC_011601.1 1368150 1369829 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1368150..1369829) Escherichia coli O127:H6 str. E2348/69 7061481 YP_002328870.1 CDS prs NC_011601.1 1369954 1370901 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1369954..1370901) Escherichia coli O127:H6 str. E2348/69 7061483 YP_002328871.1 CDS ipk NC_011601.1 1371052 1371903 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1371052..1371903) Escherichia coli O127:H6 str. E2348/69 7061314 YP_002328872.1 CDS lolB NC_011601.1 1371903 1372526 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB complement(1371903..1372526) Escherichia coli O127:H6 str. E2348/69 7063554 YP_002328873.1 CDS hemA NC_011601.1 1372740 1373996 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1372740..1373996 Escherichia coli O127:H6 str. E2348/69 7061555 YP_002328874.1 CDS prfA NC_011601.1 1374038 1375120 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1374038..1375120 Escherichia coli O127:H6 str. E2348/69 7064291 YP_002328875.1 CDS prmC NC_011601.1 1375120 1375953 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1375120..1375953 Escherichia coli O127:H6 str. E2348/69 7061284 YP_002328876.1 CDS ychQ NC_011601.1 1375950 1376342 D transcriptional regulator 1375950..1376342 Escherichia coli O127:H6 str. E2348/69 7061295 YP_002328877.1 CDS ychA NC_011601.1 1376346 1377155 D transcriptional regulator 1376346..1377155 Escherichia coli O127:H6 str. E2348/69 7061486 YP_002328878.1 CDS kdsA NC_011601.1 1377191 1378045 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1377191..1378045 Escherichia coli O127:H6 str. E2348/69 7061478 YP_002328879.1 CDS ldrA NC_011601.1 1378194 1378301 R toxic polypeptide, small complement(1378194..1378301) Escherichia coli O127:H6 str. E2348/69 7063578 YP_002328880.1 CDS chaA NC_011601.1 1378706 1379806 R calcium/sodium:proton antiporter complement(1378706..1379806) Escherichia coli O127:H6 str. E2348/69 7063971 YP_002328881.1 CDS chaB NC_011601.1 1380076 1380306 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1380076..1380306 Escherichia coli O127:H6 str. E2348/69 7064350 YP_002328882.1 CDS chaC NC_011601.1 1380464 1381159 D regulatory protein for cation transport 1380464..1381159 Escherichia coli O127:H6 str. E2348/69 7064351 YP_002328883.1 CDS ychN NC_011601.1 1381203 1381556 R hypothetical protein complement(1381203..1381556) Escherichia coli O127:H6 str. E2348/69 7064352 YP_002328884.1 CDS ychO NC_011601.1 1381741 1383135 D hypothetical protein 1381741..1383135 Escherichia coli O127:H6 str. E2348/69 7061484 YP_002328885.1 CDS narL NC_011601.1 1383136 1383786 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1383136..1383786) Escherichia coli O127:H6 str. E2348/69 7061485 YP_002328886.1 CDS narX NC_011601.1 1383779 1385575 R nitrate/nitrite sensor protein NarX complement(1383779..1385575) Escherichia coli O127:H6 str. E2348/69 7060936 YP_002328887.1 CDS narK NC_011601.1 1385914 1387305 D nitrate/nitrite transporter 1385914..1387305 Escherichia coli O127:H6 str. E2348/69 7065373 YP_002328888.1 CDS narG NC_011601.1 1387698 1391441 D nitrate reductase 1 subunit alpha 1387698..1391441 Escherichia coli O127:H6 str. E2348/69 7060935 YP_002328889.1 CDS narH NC_011601.1 1391438 1392976 D nitrate reductase 1 subunit, beta (Fe-S) 1391438..1392976 Escherichia coli O127:H6 str. E2348/69 7060931 YP_002328890.1 CDS narJ NC_011601.1 1392973 1393683 D molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 1392973..1393683 Escherichia coli O127:H6 str. E2348/69 7060932 YP_002328891.1 CDS narI NC_011601.1 1393683 1394360 D nitrate reductase 1 subunit gamma (cytochrome b(NR)) 1393683..1394360 Escherichia coli O127:H6 str. E2348/69 7060934 YP_002328892.1 CDS E2348C_1352 NC_011601.1 1394472 1395479 D hypothetical protein 1394472..1395479 Escherichia coli O127:H6 str. E2348/69 7060933 YP_002328893.1 CDS E2348C_1353 NC_011601.1 1395476 1396492 D dehydrogenase 1395476..1396492 Escherichia coli O127:H6 str. E2348/69 7064164 YP_002328894.1 CDS E2348C_1354 NC_011601.1 1396470 1397276 D hypothetical protein 1396470..1397276 Escherichia coli O127:H6 str. E2348/69 7064165 YP_002328895.1 CDS E2348C_1355 NC_011601.1 1397273 1398559 D coenzyme F390 synthetase 1397273..1398559 Escherichia coli O127:H6 str. E2348/69 7064166 YP_002328896.1 CDS E2348C_1356 NC_011601.1 1398556 1399158 D hypothetical protein 1398556..1399158 Escherichia coli O127:H6 str. E2348/69 7064167 YP_002328897.1 CDS E2348C_1357 NC_011601.1 1399151 1400275 D hypothetical protein 1399151..1400275 Escherichia coli O127:H6 str. E2348/69 7064168 YP_002328898.1 CDS E2348C_1358 NC_011601.1 1400262 1401353 D hypothetical protein 1400262..1401353 Escherichia coli O127:H6 str. E2348/69 7064169 YP_002328899.1 CDS purU NC_011601.1 1401614 1402456 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1401614..1402456) Escherichia coli O127:H6 str. E2348/69 7062288 YP_002328900.1 CDS ychJ NC_011601.1 1402506 1402964 R hypothetical protein complement(1402506..1402964) Escherichia coli O127:H6 str. E2348/69 7063924 YP_002328901.1 CDS rssA NC_011601.1 1403038 1403982 D hypothetical protein 1403038..1403982 Escherichia coli O127:H6 str. E2348/69 7061482 YP_002328902.1 CDS rssB NC_011601.1 1404074 1405087 D response regulator of RpoS 1404074..1405087 Escherichia coli O127:H6 str. E2348/69 7064562 YP_002328903.1 CDS galU NC_011601.1 1405289 1406197 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1405289..1406197 Escherichia coli O127:H6 str. E2348/69 7064563 YP_002328904.1 CDS hns NC_011601.1 1406341 1406754 R global DNA-binding transcriptional dual regulator H-NS complement(1406341..1406754) Escherichia coli O127:H6 str. E2348/69 7061624 YP_002328905.1 CDS tdk NC_011601.1 1407358 1407975 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1407358..1407975 Escherichia coli O127:H6 str. E2348/69 7062160 YP_002328906.1 CDS adhE NC_011601.1 1409413 1412088 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1409413..1412088) Escherichia coli O127:H6 str. E2348/69 7064171 YP_002328907.1 CDS ychE NC_011601.1 1412565 1413212 D hypothetical protein 1412565..1413212 Escherichia coli O127:H6 str. E2348/69 7062406 YP_002328908.1 CDS oppA NC_011601.1 1413950 1415581 D oligopeptide transporter subunit OppA 1413950..1415581 Escherichia coli O127:H6 str. E2348/69 7061479 YP_002328909.1 CDS oppB NC_011601.1 1415667 1416587 D oligopeptide transporter permease 1415667..1416587 Escherichia coli O127:H6 str. E2348/69 7062883 YP_002328910.1 CDS oppC NC_011601.1 1416602 1417510 D oligopeptide transporter subunit OppC 1416602..1417510 Escherichia coli O127:H6 str. E2348/69 7062884 YP_002328911.1 CDS oppD NC_011601.1 1417522 1418535 D oligopeptide ABC transporter ATP-binding protein 1417522..1418535 Escherichia coli O127:H6 str. E2348/69 7062885 YP_002328912.1 CDS oppF NC_011601.1 1418532 1419536 D oligopeptide transporter subunit OppF, ATP-binding component of ABC superfamily 1418532..1419536 Escherichia coli O127:H6 str. E2348/69 7062886 YP_002328913.1 CDS yciU NC_011601.1 1419589 1419918 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1419589..1419918) Escherichia coli O127:H6 str. E2348/69 7062887 YP_002328914.1 CDS cls NC_011601.1 1419953 1421413 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1419953..1421413) Escherichia coli O127:H6 str. E2348/69 7062946 YP_002328915.1 CDS yciY NC_011601.1 1421556 1421729 D hypothetical protein 1421556..1421729 Escherichia coli O127:H6 str. E2348/69 7062813 YP_002328916.1 CDS kch NC_011601.1 1421784 1423037 R voltage-gated potassium channel complement(1421784..1423037) Escherichia coli O127:H6 str. E2348/69 7062950 YP_002328917.1 CDS yciI NC_011601.1 1423337 1423633 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the reactions based on sequence and structure similarity; hypothetical protein complement(1423337..1423633) Escherichia coli O127:H6 str. E2348/69 7063568 YP_002328918.1 CDS tonB NC_011601.1 1423857 1424579 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1423857..1424579 Escherichia coli O127:H6 str. E2348/69 7061491 YP_002328919.1 CDS yciA NC_011601.1 1424619 1425017 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase complement(1424619..1425017) Escherichia coli O127:H6 str. E2348/69 7061817 YP_002328920.1 CDS yciB NC_011601.1 1425122 1425661 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1425122..1425661) Escherichia coli O127:H6 str. E2348/69 7061487 YP_002328921.1 CDS yciC NC_011601.1 1425691 1426434 R hypothetical protein complement(1425691..1426434) Escherichia coli O127:H6 str. E2348/69 7061488 YP_002328922.1 CDS ompW NC_011601.1 1426791 1427429 D receptor for colicin S4; outer membrane protein W 1426791..1427429 Escherichia coli O127:H6 str. E2348/69 7061489 YP_002328923.1 CDS E2348C_1384 NC_011601.1 1427475 1428605 R integrase complement(1427475..1428605) Escherichia coli O127:H6 str. E2348/69 7061170 YP_002328924.1 CDS E2348C_1385 NC_011601.1 1428583 1428831 R excisionase complement(1428583..1428831) Escherichia coli O127:H6 str. E2348/69 7064172 YP_002328925.1 CDS E2348C_1386 NC_011601.1 1428896 1431367 R exonuclease complement(1428896..1431367) Escherichia coli O127:H6 str. E2348/69 7064173 YP_002328926.1 CDS E2348C_1387 NC_011601.1 1431460 1431651 R hypothetical protein complement(1431460..1431651) Escherichia coli O127:H6 str. E2348/69 7064174 YP_002328927.1 CDS E2348C_1388 NC_011601.1 1431648 1431836 R cell division inhibition protein DicB complement(1431648..1431836) Escherichia coli O127:H6 str. E2348/69 7064175 YP_002328928.1 CDS E2348C_1389 NC_011601.1 1432395 1432673 D hypothetical protein 1432395..1432673 Escherichia coli O127:H6 str. E2348/69 7065027 YP_002328929.1 CDS E2348C_1390 NC_011601.1 1432633 1433034 R hypothetical protein complement(1432633..1433034) Escherichia coli O127:H6 str. E2348/69 7064177 YP_002328930.1 CDS E2348C_1391 NC_011601.1 1433046 1433279 R hypothetical protein complement(1433046..1433279) Escherichia coli O127:H6 str. E2348/69 7064178 YP_002328931.1 CDS E2348C_1392 NC_011601.1 1433464 1433883 R phage repressor protein complement(1433464..1433883) Escherichia coli O127:H6 str. E2348/69 7064179 YP_002328932.1 CDS E2348C_1393 NC_011601.1 1433984 1434265 D hypothetical protein 1433984..1434265 Escherichia coli O127:H6 str. E2348/69 7064180 YP_002328933.1 CDS E2348C_1394 NC_011601.1 1434249 1434674 D phage regulatory protein 1434249..1434674 Escherichia coli O127:H6 str. E2348/69 7064181 YP_002328934.1 CDS E2348C_1395 NC_011601.1 1434697 1435659 D replication protein 1434697..1435659 Escherichia coli O127:H6 str. E2348/69 7064182 YP_002328935.1 CDS E2348C_1396 NC_011601.1 1435700 1436122 D hypothetical protein 1435700..1436122 Escherichia coli O127:H6 str. E2348/69 7064183 YP_002328936.1 CDS E2348C_1397 NC_011601.1 1436366 1436677 D hypothetical protein 1436366..1436677 Escherichia coli O127:H6 str. E2348/69 7064184 YP_002328937.1 CDS E2348C_1398 NC_011601.1 1436978 1437331 D antitermination protein 1436978..1437331 Escherichia coli O127:H6 str. E2348/69 7064185 YP_002328938.1 CDS E2348C_1399 NC_011601.1 1437328 1437969 R hypothetical protein complement(1437328..1437969) Escherichia coli O127:H6 str. E2348/69 7064186 YP_002328939.1 CDS E2348C_1400 NC_011601.1 1437962 1438390 R hypothetical protein complement(1437962..1438390) Escherichia coli O127:H6 str. E2348/69 7064187 YP_002328940.1 CDS E2348C_1401 NC_011601.1 1438387 1439478 R hypothetical protein complement(1438387..1439478) Escherichia coli O127:H6 str. E2348/69 7064188 YP_002328941.1 CDS E2348C_1402 NC_011601.1 1439768 1439980 D prophage maintenance protein 1439768..1439980 Escherichia coli O127:H6 str. E2348/69 7064189 YP_002328942.1 CDS E2348C_1403 NC_011601.1 1439825 1439980 D host killing protein 1439825..1439980 Escherichia coli O127:H6 str. E2348/69 7064190 YP_002328943.1 CDS E2348C_1404 NC_011601.1 1440147 1440425 D hypothetical protein 1440147..1440425 Escherichia coli O127:H6 str. E2348/69 7064191 YP_002328944.1 CDS E2348C_1405 NC_011601.1 1440427 1441476 D hypothetical protein 1440427..1441476 Escherichia coli O127:H6 str. E2348/69 7064192 YP_002328945.1 CDS E2348C_1406 NC_011601.1 1441489 1441848 D crossover junction endodeoxyribonuclease 1441489..1441848 Escherichia coli O127:H6 str. E2348/69 7064193 YP_002328946.1 CDS E2348C_1407 NC_011601.1 1441845 1442534 D antitermination protein 1441845..1442534 Escherichia coli O127:H6 str. E2348/69 7064194 YP_002328947.1 CDS E2348C_1408 NC_011601.1 1443111 1444484 R transposase of ISEc13 complement(1443111..1444484) Escherichia coli O127:H6 str. E2348/69 7064988 YP_002328948.1 CDS E2348C_1409 NC_011601.1 1445019 1446872 D hypothetical protein 1445019..1446872 Escherichia coli O127:H6 str. E2348/69 7064196 YP_002328949.1 CDS E2348C_1410 NC_011601.1 1447023 1447238 D holin protein 1447023..1447238 Escherichia coli O127:H6 str. E2348/69 7064197 YP_002328950.1 CDS E2348C_1411 NC_011601.1 1447243 1447593 D hypothetical protein 1447243..1447593 Escherichia coli O127:H6 str. E2348/69 7064198 YP_002328951.1 CDS E2348C_1412 NC_011601.1 1447657 1448190 D endolysin 1447657..1448190 Escherichia coli O127:H6 str. E2348/69 7064199 YP_002328952.1 CDS E2348C_1413 NC_011601.1 1448346 1448480 D hypothetical protein 1448346..1448480 Escherichia coli O127:H6 str. E2348/69 7064200 YP_002328953.1 CDS E2348C_1414 NC_011601.1 1448518 1448733 D hypothetical protein 1448518..1448733 Escherichia coli O127:H6 str. E2348/69 7064201 YP_002328954.1 CDS E2348C_1415 NC_011601.1 1448833 1449327 D endopeptidase 1448833..1449327 Escherichia coli O127:H6 str. E2348/69 7064202 YP_002328955.1 CDS E2348C_1416 NC_011601.1 1449053 1449238 D lipoprotein Rz1 1449053..1449238 Escherichia coli O127:H6 str. E2348/69 7064203 YP_002328956.1 CDS E2348C_1417 NC_011601.1 1449324 1449548 D hypothetical protein 1449324..1449548 Escherichia coli O127:H6 str. E2348/69 7064204 YP_002328957.1 CDS E2348C_1418 NC_011601.1 1449747 1449947 R hypothetical protein complement(1449747..1449947) Escherichia coli O127:H6 str. E2348/69 7064205 YP_002328958.1 CDS E2348C_1419 NC_011601.1 1449989 1450354 D DNase 1449989..1450354 Escherichia coli O127:H6 str. E2348/69 7064206 YP_002328959.1 CDS E2348C_1420 NC_011601.1 1450645 1451208 D terminase small subunit 1450645..1451208 Escherichia coli O127:H6 str. E2348/69 7064207 YP_002328960.1 CDS E2348C_1421 NC_011601.1 1451205 1452866 D terminase large subunit 1451205..1452866 Escherichia coli O127:H6 str. E2348/69 7064208 YP_002328961.1 CDS E2348C_1422 NC_011601.1 1452930 1454867 D head protein/prohead protease 1452930..1454867 Escherichia coli O127:H6 str. E2348/69 7064209 YP_002328962.1 CDS E2348C_1423 NC_011601.1 1454912 1455133 D hypothetical protein 1454912..1455133 Escherichia coli O127:H6 str. E2348/69 7064210 YP_002328963.1 CDS E2348C_1424 NC_011601.1 1455079 1457664 D portal protein 1455079..1457664 Escherichia coli O127:H6 str. E2348/69 7064211 YP_002328964.1 CDS E2348C_1425 NC_011601.1 1457661 1457987 D DNA packaging protein 1457661..1457987 Escherichia coli O127:H6 str. E2348/69 7064212 YP_002328965.1 CDS E2348C_1426 NC_011601.1 1457997 1458347 D head-tail adapotor 1457997..1458347 Escherichia coli O127:H6 str. E2348/69 7064213 YP_002328966.1 CDS E2348C_1427 NC_011601.1 1458344 1458790 D minor tail protein 1458344..1458790 Escherichia coli O127:H6 str. E2348/69 7064214 YP_002328967.1 CDS E2348C_1428 NC_011601.1 1458787 1459131 D minor tail protein 1458787..1459131 Escherichia coli O127:H6 str. E2348/69 7064215 YP_002328968.1 CDS E2348C_1429 NC_011601.1 1459196 1459912 D major tail protein 1459196..1459912 Escherichia coli O127:H6 str. E2348/69 7064216 YP_002328969.1 CDS E2348C_1430 NC_011601.1 1459927 1460301 D minor tail protein 1459927..1460301 Escherichia coli O127:H6 str. E2348/69 7064217 YP_002328970.1 CDS E2348C_1431 NC_011601.1 1460325 1460606 D minor tail protein 1460325..1460606 Escherichia coli O127:H6 str. E2348/69 7064218 YP_002328971.1 CDS E2348C_1432 NC_011601.1 1460654 1463896 D tail length tape measure protein 1460654..1463896 Escherichia coli O127:H6 str. E2348/69 7064219 YP_002328972.1 CDS E2348C_1433 NC_011601.1 1463889 1464230 D minor tail protein 1463889..1464230 Escherichia coli O127:H6 str. E2348/69 7064220 YP_002328973.1 CDS E2348C_1434 NC_011601.1 1464230 1464928 D minor tail protein 1464230..1464928 Escherichia coli O127:H6 str. E2348/69 7064221 YP_002328974.1 CDS E2348C_1435 NC_011601.1 1464934 1465677 D tail assembly protein 1464934..1465677 Escherichia coli O127:H6 str. E2348/69 7064222 YP_002328975.1 CDS E2348C_1436 NC_011601.1 1465575 1466255 D tail assembly protein 1465575..1466255 Escherichia coli O127:H6 str. E2348/69 7064223 YP_002328976.1 CDS E2348C_1437 NC_011601.1 1466496 1469969 D host specificity protein 1466496..1469969 Escherichia coli O127:H6 str. E2348/69 7064224 YP_002328977.1 CDS E2348C_1438 NC_011601.1 1470037 1470636 D outer membrane precursor Lom 1470037..1470636 Escherichia coli O127:H6 str. E2348/69 7064225 YP_002328978.1 CDS E2348C_1439 NC_011601.1 1470788 1472065 D side tail fiber protein 1470788..1472065 Escherichia coli O127:H6 str. E2348/69 7064226 YP_002328979.1 CDS E2348C_1440 NC_011601.1 1472067 1472336 D hypothetical protein 1472067..1472336 Escherichia coli O127:H6 str. E2348/69 7064227 YP_002328980.1 CDS E2348C_1441 NC_011601.1 1472557 1473099 D hypothetical protein 1472557..1473099 Escherichia coli O127:H6 str. E2348/69 7064228 YP_002328981.1 CDS E2348C_1442 NC_011601.1 1473581 1474903 R T3SS secreted effector NleA/EspI-like protein complement(1473581..1474903) Escherichia coli O127:H6 str. E2348/69 7064445 YP_002328982.1 CDS E2348C_1444 NC_011601.1 1476724 1477635 D T3SS secreted effector NleH-like protein 1476724..1477635 Escherichia coli O127:H6 str. E2348/69 7064448 YP_002328983.1 CDS E2348C_1445 NC_011601.1 1477701 1478270 D T3SS secreted effector NleF-like protein 1477701..1478270 Escherichia coli O127:H6 str. E2348/69 7064449 YP_002328984.1 CDS E2348C_1448 NC_011601.1 1480807 1481265 R transposase of IS200C complement(1480807..1481265) Escherichia coli O127:H6 str. E2348/69 7064990 YP_002328985.1 CDS E2348C_1449 NC_011601.1 1481557 1482930 D transposase of ISEc13 1481557..1482930 Escherichia coli O127:H6 str. E2348/69 7064991 YP_002328986.1 CDS trpA NC_011601.1 1483006 1483812 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1483006..1483812) Escherichia coli O127:H6 str. E2348/69 7064451 YP_002328987.1 CDS trpB NC_011601.1 1483812 1485005 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1483812..1485005) Escherichia coli O127:H6 str. E2348/69 7062253 YP_002328988.1 CDS trpC NC_011601.1 1485017 1486375 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1485017..1486375) Escherichia coli O127:H6 str. E2348/69 7062254 YP_002328989.1 CDS trpD NC_011601.1 1486379 1487974 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1486379..1487974) Escherichia coli O127:H6 str. E2348/69 7062255 YP_002328990.1 CDS trpE NC_011601.1 1487974 1489530 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1487974..1489530) Escherichia coli O127:H6 str. E2348/69 7062256 YP_002328992.1 CDS trpH NC_011601.1 1489804 1490685 D hypothetical protein 1489804..1490685 Escherichia coli O127:H6 str. E2348/69 7062259 YP_002328993.1 CDS yciO NC_011601.1 1490682 1491302 D hypothetical protein 1490682..1491302 Escherichia coli O127:H6 str. E2348/69 7062258 YP_002328994.1 CDS yciQ NC_011601.1 1491330 1493219 D hypothetical protein 1491330..1493219 Escherichia coli O127:H6 str. E2348/69 7061495 YP_002328995.1 CDS rluB NC_011601.1 1493432 1494307 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1493432..1494307 Escherichia coli O127:H6 str. E2348/69 7061496 YP_002328996.1 CDS btuR NC_011601.1 1494347 1494937 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1494347..1494937) Escherichia coli O127:H6 str. E2348/69 7060839 YP_002328997.1 CDS yciK NC_011601.1 1494934 1495692 R short chain dehydrogenase complement(1494934..1495692) Escherichia coli O127:H6 str. E2348/69 7064312 YP_002328998.1 CDS sohB NC_011601.1 1495912 1496961 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1495912..1496961 Escherichia coli O127:H6 str. E2348/69 7061492 YP_002328999.1 CDS yciN NC_011601.1 1496997 1497248 R hypothetical protein complement(1496997..1497248) Escherichia coli O127:H6 str. E2348/69 7062735 YP_002329000.1 CDS topA NC_011601.1 1497628 1500225 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1497628..1500225 Escherichia coli O127:H6 str. E2348/69 7061494 YP_002329001.1 CDS cysB NC_011601.1 1500435 1501409 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1500435..1501409 Escherichia coli O127:H6 str. E2348/69 7061818 YP_002329002.1 CDS ymiA NC_011601.1 1501740 1501868 D hypothetical protein 1501740..1501868 Escherichia coli O127:H6 str. E2348/69 7065194 YP_002329003.1 CDS yciX NC_011601.1 1501871 1502038 D hypothetical protein 1501871..1502038 Escherichia coli O127:H6 str. E2348/69 7062036 YP_002329004.1 CDS acnA NC_011601.1 1502410 1505085 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1502410..1505085 Escherichia coli O127:H6 str. E2348/69 7062949 YP_002329005.1 CDS ribA NC_011601.1 1505149 1505739 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1505149..1505739) Escherichia coli O127:H6 str. E2348/69 7062390 YP_002329006.1 CDS pgpB NC_011601.1 1505909 1506673 D phosphatidylglycerophosphatase B 1505909..1506673 Escherichia coli O127:H6 str. E2348/69 7060818 YP_002329007.1 CDS yciS NC_011601.1 1506822 1507130 D hypothetical protein 1506822..1507130 Escherichia coli O127:H6 str. E2348/69 7060718 YP_002329008.1 CDS yciM NC_011601.1 1507137 1508306 D tetratricopeptide repeat protein 1507137..1508306 Escherichia coli O127:H6 str. E2348/69 7061497 YP_002329009.1 CDS pyrF NC_011601.1 1508498 1509235 D orotidine-5'-phosphate decarboxylase 1508498..1509235 Escherichia coli O127:H6 str. E2348/69 7061493 YP_002329010.1 CDS yciH NC_011601.1 1509235 1509561 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1509235..1509561 Escherichia coli O127:H6 str. E2348/69 7063933 YP_002329011.1 CDS osmB NC_011601.1 1509687 1509905 R lipoprotein complement(1509687..1509905) Escherichia coli O127:H6 str. E2348/69 7061490 YP_002329012.1 CDS yciT NC_011601.1 1510174 1510923 R DNA-binding transcriptional regulator complement(1510174..1510923) Escherichia coli O127:H6 str. E2348/69 7062889 YP_002329013.1 CDS yciZ NC_011601.1 1511013 1511186 R hypothetical protein complement(1511013..1511186) Escherichia coli O127:H6 str. E2348/69 7061498 YP_002329014.1 CDS gmr NC_011601.1 1511334 1513292 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1511334..1513292) Escherichia coli O127:H6 str. E2348/69 7062951 YP_002329015.1 CDS E2348C_1479 NC_011601.1 1513622 1514080 R transposase of IS200C complement(1513622..1514080) Escherichia coli O127:H6 str. E2348/69 7064992 YP_002329016.1 CDS rnb NC_011601.1 1514265 1516199 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1514265..1516199) Escherichia coli O127:H6 str. E2348/69 7064452 YP_002329017.1 CDS yciW NC_011601.1 1516239 1517393 R oxidoreductase complement(1516239..1517393) Escherichia coli O127:H6 str. E2348/69 7060847 YP_002329018.1 CDS fabI NC_011601.1 1517538 1518326 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1517538..1518326) Escherichia coli O127:H6 str. E2348/69 7062948 YP_002329019.1 CDS E2348C_1483 NC_011601.1 1518804 1519370 D transcription regulatory protein 1518804..1519370 Escherichia coli O127:H6 str. E2348/69 7062068 YP_002329020.1 CDS E2348C_1484 NC_011601.1 1519519 1520640 D multidrug-efflux transport protein 1519519..1520640 Escherichia coli O127:H6 str. E2348/69 7064453 YP_002329021.1 CDS E2348C_1485 NC_011601.1 1520640 1523747 D multidrug-efflux transport protein 1520640..1523747 Escherichia coli O127:H6 str. E2348/69 7064454 YP_002329022.1 CDS E2348C_1486 NC_011601.1 1523751 1525124 D outer membrane channel protein 1523751..1525124 Escherichia coli O127:H6 str. E2348/69 7064455 YP_002329023.1 CDS E2348C_1487 NC_011601.1 1525133 1526296 D membrane transport protein 1525133..1526296 Escherichia coli O127:H6 str. E2348/69 7064456 YP_002329024.1 CDS E2348C_1488 NC_011601.1 1526326 1527699 R transposase of ISEc13 complement(1526326..1527699) Escherichia coli O127:H6 str. E2348/69 7064993 YP_002329025.1 CDS sapF NC_011601.1 1527902 1528708 R ATP-binding protein SapF of peptide transport system complement(1527902..1528708) Escherichia coli O127:H6 str. E2348/69 7064457 YP_002329026.1 CDS sapD NC_011601.1 1528710 1529702 R ATP-binding protein SapD of peptide transport system complement(1528710..1529702) Escherichia coli O127:H6 str. E2348/69 7065331 YP_002329027.1 CDS sapC NC_011601.1 1529702 1530592 R peptide transport permease SapC; membrane component of ABC superfamily complement(1529702..1530592) Escherichia coli O127:H6 str. E2348/69 7065330 YP_002329028.1 CDS sapB NC_011601.1 1530579 1531544 R peptide transport permease SapB; membrane component of ABC superfamily complement(1530579..1531544) Escherichia coli O127:H6 str. E2348/69 7065329 YP_002329029.1 CDS sapA NC_011601.1 1531541 1533184 R peptide transport periplasmic protein SapA; periplasmic-binding component of ABC superfamily complement(1531541..1533184) Escherichia coli O127:H6 str. E2348/69 7065328 YP_002329030.1 CDS ymjA NC_011601.1 1533497 1533742 R hypothetical protein complement(1533497..1533742) Escherichia coli O127:H6 str. E2348/69 7065327 YP_002329031.1 CDS pspF NC_011601.1 1534167 1535144 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1534167..1535144) Escherichia coli O127:H6 str. E2348/69 7062037 YP_002329032.1 CDS pspA NC_011601.1 1535311 1535979 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1535311..1535979 Escherichia coli O127:H6 str. E2348/69 7061323 YP_002329033.1 CDS pspB NC_011601.1 1536033 1536257 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1536033..1536257 Escherichia coli O127:H6 str. E2348/69 7061318 YP_002329034.1 CDS pspC NC_011601.1 1536257 1536616 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1536257..1536616 Escherichia coli O127:H6 str. E2348/69 7061319 YP_002329035.1 CDS pspD NC_011601.1 1536625 1536846 D peripheral inner membrane phage-shock protein 1536625..1536846 Escherichia coli O127:H6 str. E2348/69 7061320 YP_002329036.1 CDS pspE NC_011601.1 1536921 1537235 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1536921..1537235 Escherichia coli O127:H6 str. E2348/69 7061321 YP_002329037.1 CDS ycjM NC_011601.1 1537449 1539128 D glucosyltransferase 1537449..1539128 Escherichia coli O127:H6 str. E2348/69 7061322 YP_002329038.1 CDS ycjN NC_011601.1 1539142 1540434 D sugar transporter subunit: periplasmic-binding component of ABC superfamily 1539142..1540434 Escherichia coli O127:H6 str. E2348/69 7062954 YP_002329039.1 CDS ycjO NC_011601.1 1540455 1541336 D sugar transporter subunit: membrane component of ABC superfamily 1540455..1541336 Escherichia coli O127:H6 str. E2348/69 7062955 YP_002329040.1 CDS ycjP NC_011601.1 1541323 1542165 D sugar transporter subunit: membrane component of ABC superfamily 1541323..1542165 Escherichia coli O127:H6 str. E2348/69 7062956 YP_002329041.1 CDS ycjQ NC_011601.1 1542196 1543248 D oxidoreductase, Zn-dependent and NAD(P)-binding 1542196..1543248 Escherichia coli O127:H6 str. E2348/69 7062957 YP_002329042.1 CDS ycjR NC_011601.1 1543267 1544055 D hypothetical protein 1543267..1544055 Escherichia coli O127:H6 str. E2348/69 7062958 YP_002329043.1 CDS ycjS NC_011601.1 1544065 1545120 D oxidoreductase, NADH-binding 1544065..1545120 Escherichia coli O127:H6 str. E2348/69 7062959 YP_002329044.1 CDS E2348C_1509 NC_011601.1 1547370 1548743 D transposase of ISEc13 1547370..1548743 Escherichia coli O127:H6 str. E2348/69 7064994 YP_002329045.1 CDS ycjU NC_011601.1 1548940 1549599 D beta-phosphoglucomutase 1548940..1549599 Escherichia coli O127:H6 str. E2348/69 7064458 YP_002329046.1 CDS ycjV NC_011601.1 1549613 1550695 D sugar transporter subunit: ATP-binding component of ABC superfamily 1549613..1550695 Escherichia coli O127:H6 str. E2348/69 7062961 YP_002329047.1 CDS ompG NC_011601.1 1550740 1551645 D outer membrane porin OmpG 1550740..1551645 Escherichia coli O127:H6 str. E2348/69 7062962 YP_002329048.1 CDS ycjW NC_011601.1 1551696 1552694 R DNA-binding transcriptional regulator complement(1551696..1552694) Escherichia coli O127:H6 str. E2348/69 7062876 YP_002329049.1 CDS ycjX NC_011601.1 1552851 1554248 D hypothetical protein 1552851..1554248 Escherichia coli O127:H6 str. E2348/69 7062963 YP_002329050.1 CDS ycjF NC_011601.1 1554245 1555306 D hypothetical protein 1554245..1555306 Escherichia coli O127:H6 str. E2348/69 7062964 YP_002329051.1 CDS tyrR NC_011601.1 1555454 1556995 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1555454..1556995 Escherichia coli O127:H6 str. E2348/69 7062952 YP_002329052.1 CDS tpx NC_011601.1 1557039 1557545 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1557039..1557545) Escherichia coli O127:H6 str. E2348/69 7062286 YP_002329053.1 CDS ycjG NC_011601.1 1557664 1558629 D L-Ala-D/L-Glu epimerase 1557664..1558629 Escherichia coli O127:H6 str. E2348/69 7062231 YP_002329054.1 CDS mpaA NC_011601.1 1558604 1559332 R murein peptide amidase A complement(1558604..1559332) Escherichia coli O127:H6 str. E2348/69 7062953 YP_002329055.1 CDS ymjC NC_011601.1 1559623 1560261 R NAD-dependent epimerase/dehydratase complement(1559623..1560261) Escherichia coli O127:H6 str. E2348/69 7063823 YP_002329056.1 CDS ycjY NC_011601.1 1560332 1561249 R hydrolase complement(1560332..1561249) Escherichia coli O127:H6 str. E2348/69 7062038 YP_002329057.1 CDS ycjZ NC_011601.1 1561390 1562289 D DNA-binding transcriptional regulator 1561390..1562289 Escherichia coli O127:H6 str. E2348/69 7062965 YP_002329058.1 CDS mppA NC_011601.1 1562626 1564239 D murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit 1562626..1564239 Escherichia coli O127:H6 str. E2348/69 7062966 YP_002329059.1 CDS ynaI NC_011601.1 1564290 1565321 R hypothetical protein complement(1564290..1565321) Escherichia coli O127:H6 str. E2348/69 7063826 YP_002329060.1 CDS ynaJ NC_011601.1 1565565 1565822 D hypothetical protein 1565565..1565822 Escherichia coli O127:H6 str. E2348/69 7062039 YP_002329061.1 CDS uspE NC_011601.1 1565872 1566822 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1565872..1566822) Escherichia coli O127:H6 str. E2348/69 7062040 YP_002329062.1 CDS fnr NC_011601.1 1566974 1567726 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1566974..1567726) Escherichia coli O127:H6 str. E2348/69 7062336 YP_002329063.1 CDS ogt NC_011601.1 1567921 1568436 R O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1567921..1568436) Escherichia coli O127:H6 str. E2348/69 7061936 YP_002329064.1 CDS E2348C_1529 NC_011601.1 1568968 1569783 R hypothetical protein complement(1568968..1569783) Escherichia coli O127:H6 str. E2348/69 7063559 YP_002329065.1 CDS E2348C_1530 NC_011601.1 1569877 1570908 D multidrug resistance efflux pump, HlyD family 1569877..1570908 Escherichia coli O127:H6 str. E2348/69 7064459 YP_002329066.1 CDS ydaL NC_011601.1 1572613 1573176 D hypothetical protein 1572613..1573176 Escherichia coli O127:H6 str. E2348/69 7064461 YP_002329067.1 CDS zntB NC_011601.1 1574596 1575579 D zinc transporter 1574596..1575579 Escherichia coli O127:H6 str. E2348/69 7062968 YP_002329068.1 CDS dbpA NC_011601.1 1576057 1577430 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1576057..1577430 Escherichia coli O127:H6 str. E2348/69 7061145 YP_002329069.1 CDS ttcA NC_011601.1 1577559 1578494 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1577559..1578494) Escherichia coli O127:H6 str. E2348/69 7065225 YP_002329070.1 CDS uspF NC_011601.1 1580818 1581252 R stress-induced protein, ATP-binding protein complement(1580818..1581252) Escherichia coli O127:H6 str. E2348/69 7061142 YP_002329071.1 CDS ompN NC_011601.1 1581393 1582526 R outer membrane pore protein N, non-specific complement(1581393..1582526) Escherichia coli O127:H6 str. E2348/69 7062337 YP_002329072.1 CDS ydbK NC_011601.1 1582891 1586415 R fused pyruvate-flavodoxin oxidoreductase: conserved protein/conserved protein/FeS binding protein complement(1582891..1586415) Escherichia coli O127:H6 str. E2348/69 7063786 YP_002329073.1 CDS ydbJ NC_011601.1 1586689 1586955 D hypothetical protein 1586689..1586955 Escherichia coli O127:H6 str. E2348/69 7062972 YP_002329074.1 CDS hslJ NC_011601.1 1586952 1587374 R heat-inducible protein complement(1586952..1587374) Escherichia coli O127:H6 str. E2348/69 7062971 YP_002329075.1 CDS ldhA NC_011601.1 1587485 1588474 R fermentative D-lactate dehydrogenase, NAD-dependent complement(1587485..1588474) Escherichia coli O127:H6 str. E2348/69 7062182 YP_002329076.1 CDS ydbH NC_011601.1 1588682 1591321 D hypothetical protein 1588682..1591321 Escherichia coli O127:H6 str. E2348/69 7061514 YP_002329077.1 CDS ynbE NC_011601.1 1591318 1591503 D lipoprotein 1591318..1591503 Escherichia coli O127:H6 str. E2348/69 7062970 YP_002329078.1 CDS ydbL NC_011601.1 1591511 1591837 D hypothetical protein 1591511..1591837 Escherichia coli O127:H6 str. E2348/69 7062041 YP_002329079.1 CDS ydbC NC_011601.1 1593171 1594037 D oxidoreductase 1593171..1594037 Escherichia coli O127:H6 str. E2348/69 7062899 YP_002329080.1 CDS E2348C_1549 NC_011601.1 1594073 1595446 R transposase of ISEc13 complement(1594073..1595446) Escherichia coli O127:H6 str. E2348/69 7064995 YP_002329081.1 CDS azoR NC_011601.1 1595638 1596243 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1595638..1596243) Escherichia coli O127:H6 str. E2348/69 7064462 YP_002329082.1 CDS hrpA NC_011601.1 1596501 1600346 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1596501..1600346 Escherichia coli O127:H6 str. E2348/69 7062489 YP_002329083.1 CDS ydcF NC_011601.1 1600620 1601420 D hypothetical protein 1600620..1601420 Escherichia coli O127:H6 str. E2348/69 7062178 YP_002329084.1 CDS aldA NC_011601.1 1601617 1603056 D NAD-linked; aldehyde dehydrogenase 1601617..1603056 Escherichia coli O127:H6 str. E2348/69 7062974 YP_002329085.1 CDS gapC NC_011601.1 1603098 1604099 R glyceraldehyde-3-phosphate dehydrogenase complement(1603098..1604099) Escherichia coli O127:H6 str. E2348/69 7062435 YP_002329086.1 CDS cybB NC_011601.1 1604288 1604818 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1604288..1604818 Escherichia coli O127:H6 str. E2348/69 7061626 YP_002329087.1 CDS ydcA NC_011601.1 1605063 1605236 D hypothetical protein 1605063..1605236 Escherichia coli O127:H6 str. E2348/69 7064594 YP_002329088.1 CDS E2348C_1558 NC_011601.1 1605864 1606940 R transposase of ISEc21 complement(1605864..1606940) Escherichia coli O127:H6 str. E2348/69 7064997 YP_002329089.1 CDS E2348C_1560 NC_011601.1 1607778 1608080 R transposase Orf1 of IS911 complement(1607778..1608080) Escherichia coli O127:H6 str. E2348/69 7064463 YP_002329090.1 CDS E2348C_1562 NC_011601.1 1608734 1610107 R transposase of ISEc13 complement(1608734..1610107) Escherichia coli O127:H6 str. E2348/69 7065000 YP_002329091.1 CDS E2348C_1564 NC_011601.1 1610574 1611095 R transposase Orf1 of IS150 complement(1610574..1611095) Escherichia coli O127:H6 str. E2348/69 7064464 YP_002329092.1 CDS ydcI NC_011601.1 1611816 1612739 R DNA-binding transcriptional regulator complement(1611816..1612739) Escherichia coli O127:H6 str. E2348/69 7062238 YP_002329093.1 CDS ydcJ NC_011601.1 1612956 1614299 D hypothetical protein 1612956..1614299 Escherichia coli O127:H6 str. E2348/69 7062976 YP_002329094.1 CDS mdoD NC_011601.1 1614524 1616179 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1614524..1616179 Escherichia coli O127:H6 str. E2348/69 7062977 YP_002329095.1 CDS ydcH NC_011601.1 1616319 1616543 D hypothetical protein 1616319..1616543 Escherichia coli O127:H6 str. E2348/69 7065303 YP_002329096.1 CDS rimL NC_011601.1 1616606 1617145 D ribosomal-protein-L7/L12-serine acetyltransferase 1616606..1617145 Escherichia coli O127:H6 str. E2348/69 7062975 YP_002329097.1 CDS ydcK NC_011601.1 1617137 1618117 R hypothetical protein complement(1617137..1618117) Escherichia coli O127:H6 str. E2348/69 7060830 YP_002329098.1 CDS tehA NC_011601.1 1618241 1619233 D potassium-tellurite ethidium and proflavin transporter 1618241..1619233 Escherichia coli O127:H6 str. E2348/69 7062978 YP_002329099.1 CDS tehB NC_011601.1 1619230 1619823 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1619230..1619823 Escherichia coli O127:H6 str. E2348/69 7061774 YP_002329100.1 CDS ydcL NC_011601.1 1620126 1620794 D lipoprotein 1620126..1620794 Escherichia coli O127:H6 str. E2348/69 7061775 YP_002329101.1 CDS ydcO NC_011601.1 1620829 1622001 R benzoate transporter complement(1620829..1622001) Escherichia coli O127:H6 str. E2348/69 7062979 YP_002329102.1 CDS ydcN NC_011601.1 1622093 1622629 D DNA-binding transcriptional regulator 1622093..1622629 Escherichia coli O127:H6 str. E2348/69 7062981 YP_002329103.1 CDS ydcP NC_011601.1 1622702 1624663 D peptidase 1622702..1624663 Escherichia coli O127:H6 str. E2348/69 7062980 YP_002329104.1 CDS yncJ NC_011601.1 1624755 1624985 R hypothetical protein complement(1624755..1624985) Escherichia coli O127:H6 str. E2348/69 7062982 YP_002329105.1 CDS ydcR NC_011601.1 1625335 1626741 D fused DNA-binding transcriptional regulator/ amino transferase 1625335..1626741 Escherichia coli O127:H6 str. E2348/69 7062045 YP_002329106.1 CDS ydcS NC_011601.1 1626986 1628131 D spermidine/putrescine transporter subunit 1626986..1628131 Escherichia coli O127:H6 str. E2348/69 7062983 YP_002329107.1 CDS ydcT NC_011601.1 1628149 1629162 D spermidine/putrescine transporter subunit, membrane component of ABC superfamily 1628149..1629162 Escherichia coli O127:H6 str. E2348/69 7062984 YP_002329108.1 CDS ydcU NC_011601.1 1629163 1630104 D spermidine/putrescine transporter subunit 1629163..1630104 Escherichia coli O127:H6 str. E2348/69 7062985 YP_002329109.1 CDS ydcV NC_011601.1 1630094 1630888 D spermidine/putrescine transporter subunit, membrane component of ABC superfamily 1630094..1630888 Escherichia coli O127:H6 str. E2348/69 7062986 YP_002329110.1 CDS ydcW NC_011601.1 1630910 1632334 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1630910..1632334 Escherichia coli O127:H6 str. E2348/69 7062987 YP_002329111.1 CDS yncL NC_011601.1 1632431 1632526 R hypothetical protein complement(1632431..1632526) Escherichia coli O127:H6 str. E2348/69 7062988 YP_002329112.1 CDS ydcX NC_011601.1 1632721 1632894 D hypothetical protein 1632721..1632894 Escherichia coli O127:H6 str. E2348/69 7062046 YP_002329113.1 CDS ydcY NC_011601.1 1632980 1633213 D hypothetical protein 1632980..1633213 Escherichia coli O127:H6 str. E2348/69 7062989 YP_002329114.1 CDS ydcZ NC_011601.1 1633214 1633663 R hypothetical protein complement(1633214..1633663) Escherichia coli O127:H6 str. E2348/69 7062990 YP_002329115.1 CDS yncA NC_011601.1 1633660 1634178 R acyltransferase complement(1633660..1634178) Escherichia coli O127:H6 str. E2348/69 7062991 YP_002329116.1 CDS yncD NC_011601.1 1634659 1636761 R iron outer membrane transporter complement(1634659..1636761) Escherichia coli O127:H6 str. E2348/69 7064466 YP_002329117.1 CDS yncE NC_011601.1 1637003 1638064 D hypothetical protein 1637003..1638064 Escherichia coli O127:H6 str. E2348/69 7062043 YP_002329118.1 CDS ansP NC_011601.1 1638177 1639676 R L-asparagine transporter complement(1638177..1639676) Escherichia coli O127:H6 str. E2348/69 7062044 YP_002329119.1 CDS E2348C_1594 NC_011601.1 1640463 1640993 D hypothetical protein 1640463..1640993 Escherichia coli O127:H6 str. E2348/69 7061346 YP_002329120.1 CDS E2348C_1595 NC_011601.1 1641007 1641345 D hypothetical protein 1641007..1641345 Escherichia coli O127:H6 str. E2348/69 7064467 YP_002329121.1 CDS pptA NC_011601.1 1644960 1645187 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1644960..1645187 Escherichia coli O127:H6 str. E2348/69 7064470 YP_002329122.1 CDS yddH NC_011601.1 1645193 1645762 R hypothetical protein complement(1645193..1645762) Escherichia coli O127:H6 str. E2348/69 7061277 YP_002329123.1 CDS nhoA NC_011601.1 1645937 1646782 D N-hydroxyarylamine O-acetyltransferase 1645937..1646782 Escherichia coli O127:H6 str. E2348/69 7062996 YP_002329124.1 CDS yddE NC_011601.1 1646878 1647771 R hypothetical protein complement(1646878..1647771) Escherichia coli O127:H6 str. E2348/69 7065390 YP_002329125.1 CDS narV NC_011601.1 1647851 1648531 R nitrate reductase 2 (NRZ), gamma subunit complement(1647851..1648531) Escherichia coli O127:H6 str. E2348/69 7062994 YP_002329126.1 CDS narW NC_011601.1 1648528 1649223 R nitrate reductase 2 (NRZ), delta subunit (assembly subunit) complement(1648528..1649223) Escherichia coli O127:H6 str. E2348/69 7065371 YP_002329127.1 CDS narY NC_011601.1 1649223 1650767 R nitrate reductase 2 (NRZ), beta subunit complement(1649223..1650767) Escherichia coli O127:H6 str. E2348/69 7065372 YP_002329128.1 CDS narZ NC_011601.1 1650764 1654504 R nitrate reductase 2 (NRZ), alpha subunit complement(1650764..1654504) Escherichia coli O127:H6 str. E2348/69 7065374 YP_002329129.1 CDS narU NC_011601.1 1654599 1655987 R nitrate/nitrite transporter complement(1654599..1655987) Escherichia coli O127:H6 str. E2348/69 7065375 YP_002329130.1 CDS yddG NC_011601.1 1656266 1657090 R hypothetical protein complement(1656266..1657090) Escherichia coli O127:H6 str. E2348/69 7060939 YP_002329131.1 CDS fdnG NC_011601.1 1657379 1660426 D selenocysteine (Sec=>U); formate dehydrogenase-N alpha subunit 1657379..1660426 Escherichia coli O127:H6 str. E2348/69 7062995 YP_002329132.1 CDS fdnH NC_011601.1 1660439 1661323 D formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible 1660439..1661323 Escherichia coli O127:H6 str. E2348/69 7062088 YP_002329133.1 CDS fdnI NC_011601.1 1661316 1661969 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1661316..1661969 Escherichia coli O127:H6 str. E2348/69 7062089 YP_002329134.1 CDS yddM NC_011601.1 1662020 1662304 R DNA-binding transcriptional regulator complement(1662020..1662304) Escherichia coli O127:H6 str. E2348/69 7062090 YP_002329135.1 CDS adhP NC_011601.1 1662768 1663778 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1662768..1663778) Escherichia coli O127:H6 str. E2348/69 7062997 YP_002329136.1 CDS maeA NC_011601.1 1663912 1665609 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1663912..1665609) Escherichia coli O127:H6 str. E2348/69 7062407 YP_002329137.1 CDS rpsV NC_011601.1 1665765 1665902 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1665765..1665902) Escherichia coli O127:H6 str. E2348/69 7065267 YP_002329138.1 CDS bdm NC_011601.1 1666004 1666219 R biofilm-dependent modulation protein complement(1666004..1666219) Escherichia coli O127:H6 str. E2348/69 7062753 YP_002329139.1 CDS osmC NC_011601.1 1666564 1666995 D osmotically inducible, stress-inducible membrane protein 1666564..1666995 Escherichia coli O127:H6 str. E2348/69 7062505 YP_002329140.1 CDS dos NC_011601.1 1667184 1669583 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1667184..1669583) Escherichia coli O127:H6 str. E2348/69 7062890 YP_002329141.1 CDS yddW NC_011601.1 1670150 1671469 R liprotein complement(1670150..1671469) Escherichia coli O127:H6 str. E2348/69 7065055 YP_002329142.1 CDS gadC NC_011601.1 1671600 1673135 R glutamate: gamma-aminobutyric acid antiporter complement(1671600..1673135) Escherichia coli O127:H6 str. E2348/69 7062998 YP_002329143.1 CDS gadB NC_011601.1 1673291 1674691 R glutamate decarboxylase complement(1673291..1674691) Escherichia coli O127:H6 str. E2348/69 7061611 YP_002329144.1 CDS pqqL NC_011601.1 1675053 1677836 R peptidase complement(1675053..1677836) Escherichia coli O127:H6 str. E2348/69 7061610 YP_002329145.1 CDS yddB NC_011601.1 1677893 1680265 R porin complement(1677893..1680265) Escherichia coli O127:H6 str. E2348/69 7061282 YP_002329146.1 CDS yddA NC_011601.1 1680303 1681988 R fused multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component complement(1680303..1681988) Escherichia coli O127:H6 str. E2348/69 7062993 YP_002329147.1 CDS ydeM NC_011601.1 1682279 1683436 R hypothetical protein complement(1682279..1683436) Escherichia coli O127:H6 str. E2348/69 7062992 YP_002329148.1 CDS ydeN NC_011601.1 1683488 1685170 R hypothetical protein complement(1683488..1685170) Escherichia coli O127:H6 str. E2348/69 7063003 YP_002329149.1 CDS ydeO NC_011601.1 1685572 1686333 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1685572..1686333) Escherichia coli O127:H6 str. E2348/69 7063004 YP_002329150.1 CDS E2348C_1627 NC_011601.1 1686408 1686605 R hypothetical protein complement(1686408..1686605) Escherichia coli O127:H6 str. E2348/69 7063005 YP_002329151.1 CDS ydeP NC_011601.1 1686853 1689132 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase complement(1686853..1689132) Escherichia coli O127:H6 str. E2348/69 7064471 YP_002329152.1 CDS ydeQ NC_011601.1 1689471 1690385 R fimbrial protein-like protein complement(1689471..1690385) Escherichia coli O127:H6 str. E2348/69 7063006 YP_002329153.1 CDS ydeR NC_011601.1 1690444 1690947 R fimbrial protein-like protein complement(1690444..1690947) Escherichia coli O127:H6 str. E2348/69 7063007 YP_002329154.1 CDS ydeS NC_011601.1 1690960 1691490 R fimbrial protein-like protein complement(1690960..1691490) Escherichia coli O127:H6 str. E2348/69 7063008 YP_002329155.1 CDS E2348C_1632 NC_011601.1 1691504 1694155 R outer membrane usher protein complement(1691504..1694155) Escherichia coli O127:H6 str. E2348/69 7063009 YP_002329156.1 CDS E2348C_1633 NC_011601.1 1694197 1694907 R fimbrial chaperone protein complement(1694197..1694907) Escherichia coli O127:H6 str. E2348/69 7064472 YP_002329157.1 CDS E2348C_1634 NC_011601.1 1695269 1695832 R type 1 fimbrial protein complement(1695269..1695832) Escherichia coli O127:H6 str. E2348/69 7064473 YP_002329158.1 CDS E2348C_1635 NC_011601.1 1697259 1698359 D hypothetical protein 1697259..1698359 Escherichia coli O127:H6 str. E2348/69 7064474 YP_002329159.1 CDS E2348C_1636 NC_011601.1 1698837 1700663 D hypothetical protein 1698837..1700663 Escherichia coli O127:H6 str. E2348/69 7064475 YP_002329160.1 CDS E2348C_1637 NC_011601.1 1701660 1702061 D reverse transcriptase 1701660..1702061 Escherichia coli O127:H6 str. E2348/69 7061146 YP_002329161.1 CDS hipA NC_011601.1 1702682 1704004 R regulator with hipB complement(1702682..1704004) Escherichia coli O127:H6 str. E2348/69 7064477 YP_002329162.1 CDS hipB NC_011601.1 1704004 1704270 R DNA-binding transcriptional regulator HipB complement(1704004..1704270) Escherichia coli O127:H6 str. E2348/69 7062141 YP_002329163.1 CDS tam NC_011601.1 1704577 1705335 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1704577..1705335 Escherichia coli O127:H6 str. E2348/69 7062142 YP_002329164.1 CDS yneE NC_011601.1 1705339 1706253 R hypothetical protein complement(1705339..1706253) Escherichia coli O127:H6 str. E2348/69 7061751 YP_002329165.1 CDS uxaB NC_011601.1 1706450 1707901 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1706450..1707901) Escherichia coli O127:H6 str. E2348/69 7062047 YP_002329166.1 CDS yneF NC_011601.1 1708128 1709546 R diguanylate cyclase complement(1708128..1709546) Escherichia coli O127:H6 str. E2348/69 7062346 YP_002329167.1 CDS yneG NC_011601.1 1709685 1710044 R hypothetical protein complement(1709685..1710044) Escherichia coli O127:H6 str. E2348/69 7062048 YP_002329168.1 CDS yneH NC_011601.1 1710044 1710970 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1710044..1710970) Escherichia coli O127:H6 str. E2348/69 7062049 YP_002329169.1 CDS yneI NC_011601.1 1711034 1712422 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(1711034..1712422) Escherichia coli O127:H6 str. E2348/69 7062050 YP_002329170.1 CDS yneJ NC_011601.1 1712523 1713404 D DNA-binding transcriptional regulator 1712523..1713404 Escherichia coli O127:H6 str. E2348/69 7062051 YP_002329171.1 CDS ydeA NC_011601.1 1713743 1714933 D sugar efflux transporter 1713743..1714933 Escherichia coli O127:H6 str. E2348/69 7062052 YP_002329172.1 CDS marC NC_011601.1 1714958 1715623 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1714958..1715623) Escherichia coli O127:H6 str. E2348/69 7062999 YP_002329173.1 CDS marR NC_011601.1 1715835 1716269 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1715835..1716269 Escherichia coli O127:H6 str. E2348/69 7065293 YP_002329174.1 CDS marA NC_011601.1 1716290 1716673 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1716290..1716673 Escherichia coli O127:H6 str. E2348/69 7065294 YP_002329175.1 CDS marB NC_011601.1 1716705 1716923 D hypothetical protein 1716705..1716923 Escherichia coli O127:H6 str. E2348/69 7065291 YP_002329176.1 CDS eamA NC_011601.1 1716954 1717853 R O-acetylserine/cysteine export protein complement(1716954..1717853) Escherichia coli O127:H6 str. E2348/69 7065292 YP_002329177.1 CDS ydeE NC_011601.1 1718048 1719235 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1718048..1719235 Escherichia coli O127:H6 str. E2348/69 7065078 YP_002329178.1 CDS yneM NC_011601.1 1719362 1719457 D hypothetical protein 1719362..1719457 Escherichia coli O127:H6 str. E2348/69 7063000 YP_002329179.1 CDS ydeH NC_011601.1 1719676 1720566 R hypothetical protein complement(1719676..1720566) Escherichia coli O127:H6 str. E2348/69 7062053 YP_002329180.1 CDS dcp NC_011601.1 1721073 1723118 R dipeptidyl carboxypeptidase II complement(1721073..1723118) Escherichia coli O127:H6 str. E2348/69 7063002 YP_002329181.1 CDS ydfG NC_011601.1 1723255 1724001 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1723255..1724001 Escherichia coli O127:H6 str. E2348/69 7065228 YP_002329182.1 CDS ydfH NC_011601.1 1724090 1724776 D DNA-binding transcriptional regulator 1724090..1724776 Escherichia coli O127:H6 str. E2348/69 7063010 YP_002329183.1 CDS ydfZ NC_011601.1 1724953 1725156 D hypothetical protein 1724953..1725156 Escherichia coli O127:H6 str. E2348/69 7063011 YP_002329184.1 CDS ydfI NC_011601.1 1725192 1726652 R mannonate dehydrogenase complement(1725192..1726652) Escherichia coli O127:H6 str. E2348/69 7063014 YP_002329185.1 CDS ydfJ NC_011601.1 1726741 1728108 R transporter complement(1726741..1728108) Escherichia coli O127:H6 str. E2348/69 7063012 YP_002329186.1 CDS rspB NC_011601.1 1728166 1729185 R dehydrogenase complement(1728166..1729185) Escherichia coli O127:H6 str. E2348/69 7063013 YP_002329187.1 CDS rspA NC_011601.1 1729197 1730411 R dehydratase complement(1729197..1730411) Escherichia coli O127:H6 str. E2348/69 7064561 YP_002329188.1 CDS ynfA NC_011601.1 1730617 1730943 R hypothetical protein complement(1730617..1730943) Escherichia coli O127:H6 str. E2348/69 7064560 YP_002329189.1 CDS ynfB NC_011601.1 1731078 1731419 D hypothetical protein 1731078..1731419 Escherichia coli O127:H6 str. E2348/69 7062054 YP_002329190.1 CDS speG NC_011601.1 1731454 1732014 D spermidine N1-acetyltransferase 1731454..1732014 Escherichia coli O127:H6 str. E2348/69 7061180 YP_002329191.1 CDS ynfC NC_011601.1 1732017 1732727 R hypothetical protein complement(1732017..1732727) Escherichia coli O127:H6 str. E2348/69 7062746 YP_002329192.1 CDS ynfD NC_011601.1 1732835 1733140 D hypothetical protein 1732835..1733140 Escherichia coli O127:H6 str. E2348/69 7061181 YP_002329193.1 CDS ynfE NC_011601.1 1733339 1735765 D oxidoreductase subunit 1733339..1735765 Escherichia coli O127:H6 str. E2348/69 7061182 YP_002329194.1 CDS ynfF NC_011601.1 1735853 1738249 D oxidoreductase subunit 1735853..1738249 Escherichia coli O127:H6 str. E2348/69 7061183 YP_002329195.1 CDS ynfG NC_011601.1 1738260 1738877 D oxidoreductase, Fe-S subunit 1738260..1738877 Escherichia coli O127:H6 str. E2348/69 7061184 YP_002329196.1 CDS ynfH NC_011601.1 1738879 1739733 D oxidoreductase, membrane subunit 1738879..1739733 Escherichia coli O127:H6 str. E2348/69 7061185 YP_002329197.1 CDS dmsD NC_011601.1 1739776 1740390 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1739776..1740390 Escherichia coli O127:H6 str. E2348/69 7061186 YP_002329198.1 CDS clcB NC_011601.1 1740586 1741842 D voltage-gated ClC-type chloride channel ClcB 1740586..1741842 Escherichia coli O127:H6 str. E2348/69 7065043 YP_002329199.1 CDS ynfK NC_011601.1 1741839 1742492 R dethiobiotin synthetase, with altered C-ter by frameshift mutation complement(1741839..1742492) Escherichia coli O127:H6 str. E2348/69 7062807 YP_002329200.1 CDS dgsA NC_011601.1 1742617 1743837 R DNA-binding transcriptional repressor complement(1742617..1743837) Escherichia coli O127:H6 str. E2348/69 7061187 YP_002329201.1 CDS ynfL NC_011601.1 1743972 1744865 R DNA-binding transcriptional regulator complement(1743972..1744865) Escherichia coli O127:H6 str. E2348/69 7065019 YP_002329202.1 CDS ynfM NC_011601.1 1744972 1746225 D transporter 1744972..1746225 Escherichia coli O127:H6 str. E2348/69 7061188 YP_002329203.1 CDS asr NC_011601.1 1746650 1746958 D required for growth and survival under moderately acid conditions; acid shock protein 1746650..1746958 Escherichia coli O127:H6 str. E2348/69 7061189 YP_002329204.1 CDS ydgU NC_011601.1 1747051 1747134 D membrane protein 1747051..1747134 Escherichia coli O127:H6 str. E2348/69 7062464 YP_002329205.1 CDS ydgD NC_011601.1 1747234 1748055 D peptidase 1747234..1748055 Escherichia coli O127:H6 str. E2348/69 7063022 YP_002329206.1 CDS mdtI NC_011601.1 1748094 1748423 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1748094..1748423) Escherichia coli O127:H6 str. E2348/69 7063017 YP_002329207.1 CDS mdtJ NC_011601.1 1748410 1748775 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1748410..1748775) Escherichia coli O127:H6 str. E2348/69 7065314 YP_002329208.1 CDS tqsA NC_011601.1 1749187 1750221 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1749187..1750221 Escherichia coli O127:H6 str. E2348/69 7065315 YP_002329209.1 CDS pntB NC_011601.1 1750246 1751634 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1750246..1751634) Escherichia coli O127:H6 str. E2348/69 7062232 YP_002329210.1 CDS pntA NC_011601.1 1751645 1753177 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1751645..1753177) Escherichia coli O127:H6 str. E2348/69 7060765 YP_002329211.1 CDS ydgH NC_011601.1 1753701 1754645 D hypothetical protein 1753701..1754645 Escherichia coli O127:H6 str. E2348/69 7060764 YP_002329212.1 CDS ydgI NC_011601.1 1754831 1756213 D arginine/ornithine antiporter 1754831..1756213 Escherichia coli O127:H6 str. E2348/69 7063018 YP_002329213.1 CDS folM NC_011601.1 1756250 1756972 D short chain dehydrogenase 1756250..1756972 Escherichia coli O127:H6 str. E2348/69 7063019 YP_002329214.1 CDS ydgC NC_011601.1 1756969 1757304 R hypothetical protein complement(1756969..1757304) Escherichia coli O127:H6 str. E2348/69 7061944 YP_002329215.1 CDS rstA NC_011601.1 1757433 1758152 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1757433..1758152 Escherichia coli O127:H6 str. E2348/69 7063016 YP_002329216.1 CDS rstB NC_011601.1 1758156 1759457 D sensor protein RstB 1758156..1759457 Escherichia coli O127:H6 str. E2348/69 7064564 YP_002329217.1 CDS tus NC_011601.1 1759533 1760462 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1759533..1760462 Escherichia coli O127:H6 str. E2348/69 7064565 YP_002329218.1 CDS fumC NC_011601.1 1760459 1761862 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1760459..1761862) Escherichia coli O127:H6 str. E2348/69 7062281 YP_002329219.1 CDS fumA NC_011601.1 1762005 1763651 R fumarate hydratase (fumarase A), aerobic ClassI complement(1762005..1763651) Escherichia coli O127:H6 str. E2348/69 7061602 YP_002329220.1 CDS manA NC_011601.1 1763850 1765025 D mannose-6-phosphate isomerase 1763850..1765025 Escherichia coli O127:H6 str. E2348/69 7061600 YP_002329221.1 CDS ydgA NC_011601.1 1765126 1766634 D hypothetical protein 1765126..1766634 Escherichia coli O127:H6 str. E2348/69 7065283 YP_002329222.1 CDS uidB NC_011601.1 1767983 1769356 R glucuronide transporter complement(1767983..1769356) Escherichia coli O127:H6 str. E2348/69 7062314 YP_002329223.1 CDS uidA NC_011601.1 1769353 1771164 R beta-D-glucuronidase complement(1769353..1771164) Escherichia coli O127:H6 str. E2348/69 7062313 YP_002329224.1 CDS uidR NC_011601.1 1771554 1772144 R DNA-binding transcriptional repressor complement(1771554..1772144) Escherichia coli O127:H6 str. E2348/69 7062312 YP_002329225.1 CDS hdhA NC_011601.1 1772373 1773140 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1772373..1773140) Escherichia coli O127:H6 str. E2348/69 7062315 YP_002329226.1 CDS malI NC_011601.1 1773252 1774280 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1773252..1774280) Escherichia coli O127:H6 str. E2348/69 7064289 YP_002329227.1 CDS malX NC_011601.1 1774455 1776047 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1774455..1776047 Escherichia coli O127:H6 str. E2348/69 7065273 YP_002329228.1 CDS malY NC_011601.1 1776057 1777229 D bifunctional beta-cystathionase, PLP-dependent/regulator of maltose regulon 1776057..1777229 Escherichia coli O127:H6 str. E2348/69 7065280 YP_002329229.1 CDS add NC_011601.1 1777333 1778334 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1777333..1778334 Escherichia coli O127:H6 str. E2348/69 7065281 YP_002329230.1 CDS E2348C_1709 NC_011601.1 1778446 1778904 R transposase of IS200C complement(1778446..1778904) Escherichia coli O127:H6 str. E2348/69 7065002 YP_002329231.1 CDS ydgJ NC_011601.1 1779082 1780122 R oxidoreductase complement(1779082..1780122) Escherichia coli O127:H6 str. E2348/69 7064478 YP_002329232.1 CDS blr NC_011601.1 1780365 1780490 D beta-lactam resistance membrane protein Blr 1780365..1780490 Escherichia coli O127:H6 str. E2348/69 7063020 YP_002329233.1 CDS cnu NC_011601.1 1780763 1780978 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1780763..1780978 Escherichia coli O127:H6 str. E2348/69 7062529 YP_002329234.1 CDS ydgK NC_011601.1 1781064 1781504 D hypothetical protein 1781064..1781504 Escherichia coli O127:H6 str. E2348/69 7062820 YP_002329235.1 CDS rsxA NC_011601.1 1781581 1782162 D Na(+)-translocating NADH-quinone reductase subunit E 1781581..1782162 Escherichia coli O127:H6 str. E2348/69 7063021 YP_002329236.1 CDS rsxB NC_011601.1 1782162 1782740 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1782162..1782740 Escherichia coli O127:H6 str. E2348/69 7064567 YP_002329237.1 CDS rsxC NC_011601.1 1782733 1784958 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1782733..1784958 Escherichia coli O127:H6 str. E2348/69 7064568 YP_002329238.1 CDS rnfD NC_011601.1 1784959 1786017 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1784959..1786017 Escherichia coli O127:H6 str. E2348/69 7064569 YP_002329239.1 CDS rsxG NC_011601.1 1786021 1786641 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1786021..1786641 Escherichia coli O127:H6 str. E2348/69 7064570 YP_002329240.1 CDS rsxE NC_011601.1 1786645 1787340 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1786645..1787340 Escherichia coli O127:H6 str. E2348/69 7064572 YP_002329241.1 CDS nth NC_011601.1 1787340 1787975 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1787340..1787975 Escherichia coli O127:H6 str. E2348/69 7064571 YP_002329242.1 CDS tppB NC_011601.1 1788586 1790088 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1788586..1790088 Escherichia coli O127:H6 str. E2348/69 7065426 YP_002329243.1 CDS gst NC_011601.1 1790194 1790799 D glutathionine S-transferase 1790194..1790799 Escherichia coli O127:H6 str. E2348/69 7062230 YP_002329244.1 CDS pdxY NC_011601.1 1790843 1791703 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1790843..1791703) Escherichia coli O127:H6 str. E2348/69 7064269 YP_002329245.1 CDS tyrS NC_011601.1 1791765 1793039 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1791765..1793039) Escherichia coli O127:H6 str. E2348/69 7062944 YP_002329246.1 CDS pdxH NC_011601.1 1793168 1793824 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1793168..1793824) Escherichia coli O127:H6 str. E2348/69 7062287 YP_002329247.1 CDS ydhA NC_011601.1 1793883 1794206 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1793883..1794206) Escherichia coli O127:H6 str. E2348/69 7062941 YP_002329248.1 CDS anmK NC_011601.1 1794310 1795419 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1794310..1795419) Escherichia coli O127:H6 str. E2348/69 7063023 YP_002329249.1 CDS slyB NC_011601.1 1795693 1796160 D outer membrane lipoprotein 1795693..1796160 Escherichia coli O127:H6 str. E2348/69 7061343 YP_002329250.1 CDS slyA NC_011601.1 1796207 1796641 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1796207..1796641) Escherichia coli O127:H6 str. E2348/69 7062724 YP_002329251.1 CDS ydhI NC_011601.1 1796842 1797078 D hypothetical protein 1796842..1797078 Escherichia coli O127:H6 str. E2348/69 7062723 YP_002329252.1 CDS ydhJ NC_011601.1 1797081 1797938 D undecaprenyl pyrophosphate phosphatase 1797081..1797938 Escherichia coli O127:H6 str. E2348/69 7063988 YP_002329253.1 CDS ydhK NC_011601.1 1797938 1799950 D hypothetical protein 1797938..1799950 Escherichia coli O127:H6 str. E2348/69 7063989 YP_002329254.1 CDS sodC NC_011601.1 1799951 1800472 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1799951..1800472) Escherichia coli O127:H6 str. E2348/69 7063990 YP_002329255.1 CDS ydhF NC_011601.1 1800553 1801449 R oxidoreductase complement(1800553..1801449) Escherichia coli O127:H6 str. E2348/69 7062734 YP_002329256.1 CDS ydhL NC_011601.1 1801498 1801737 R hypothetical protein complement(1801498..1801737) Escherichia coli O127:H6 str. E2348/69 7063026 YP_002329257.1 CDS ydhM NC_011601.1 1801840 1802439 D DNA-binding transcriptional regulator 1801840..1802439 Escherichia coli O127:H6 str. E2348/69 7063991 YP_002329258.1 CDS nemA NC_011601.1 1802476 1803573 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1802476..1803573 Escherichia coli O127:H6 str. E2348/69 7063992 YP_002329259.1 CDS gloA NC_011601.1 1803654 1804061 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1803654..1804061 Escherichia coli O127:H6 str. E2348/69 7065379 YP_002329260.1 CDS rnt NC_011601.1 1804164 1804811 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1804164..1804811 Escherichia coli O127:H6 str. E2348/69 7061690 YP_002329261.1 CDS grxD NC_011601.1 1805183 1805530 R hypothetical protein complement(1805183..1805530) Escherichia coli O127:H6 str. E2348/69 7061821 YP_002329262.1 CDS ydhO NC_011601.1 1805865 1806692 D lipoprotein 1805865..1806692 Escherichia coli O127:H6 str. E2348/69 7064249 YP_002329263.1 CDS sodB NC_011601.1 1806820 1807401 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1806820..1807401 Escherichia coli O127:H6 str. E2348/69 7063993 YP_002329264.1 CDS ydhP NC_011601.1 1807547 1808716 R transporter complement(1807547..1808716) Escherichia coli O127:H6 str. E2348/69 7062733 YP_002329265.1 CDS ynhF NC_011601.1 1808882 1808971 R membrane protein complement(1808882..1808971) Escherichia coli O127:H6 str. E2348/69 7063994 YP_002329266.1 CDS purR NC_011601.1 1809270 1810295 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1809270..1810295 Escherichia coli O127:H6 str. E2348/69 7061190 YP_002329267.1 CDS ydhB NC_011601.1 1810292 1811224 R DNA-binding transcriptional regulator complement(1810292..1811224) Escherichia coli O127:H6 str. E2348/69 7063922 YP_002329268.1 CDS ydhC NC_011601.1 1811337 1812548 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1811337..1812548 Escherichia coli O127:H6 str. E2348/69 7063024 YP_002329269.1 CDS cfa NC_011601.1 1812833 1813981 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1812833..1813981 Escherichia coli O127:H6 str. E2348/69 7063025 YP_002329270.1 CDS ribC NC_011601.1 1814021 1814662 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1814021..1814662) Escherichia coli O127:H6 str. E2348/69 7064349 YP_002329271.1 CDS mdtK NC_011601.1 1814877 1816250 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1814877..1816250 Escherichia coli O127:H6 str. E2348/69 7060820 YP_002329272.1 CDS ydhQ NC_011601.1 1816291 1817547 R hypothetical protein complement(1816291..1817547) Escherichia coli O127:H6 str. E2348/69 7065316 YP_002329273.1 CDS ydhR NC_011601.1 1818124 1818429 D hypothetical protein 1818124..1818429 Escherichia coli O127:H6 str. E2348/69 7062356 YP_002329274.1 CDS ydhS NC_011601.1 1818555 1820159 D hypothetical protein 1818555..1820159 Escherichia coli O127:H6 str. E2348/69 7063996 YP_002329275.1 CDS ydhT NC_011601.1 1820171 1820935 R hypothetical protein complement(1820171..1820935) Escherichia coli O127:H6 str. E2348/69 7063997 YP_002329276.1 CDS ydhU NC_011601.1 1820987 1821772 R cytochrome complement(1820987..1821772) Escherichia coli O127:H6 str. E2348/69 7063998 YP_002329277.1 CDS ydhX NC_011601.1 1821769 1822488 R 4Fe-4S ferredoxin complement(1821769..1822488) Escherichia coli O127:H6 str. E2348/69 7063999 YP_002329278.1 CDS ydhW NC_011601.1 1822501 1823139 R hypothetical protein complement(1822501..1823139) Escherichia coli O127:H6 str. E2348/69 7064002 YP_002329279.1 CDS ydhV NC_011601.1 1823152 1825254 R oxidoreductase complement(1823152..1825254) Escherichia coli O127:H6 str. E2348/69 7064001 YP_002329280.1 CDS ydhY NC_011601.1 1825275 1825901 R hypothetical protein complement(1825275..1825901) Escherichia coli O127:H6 str. E2348/69 7064000 YP_002329281.1 CDS ydhZ NC_011601.1 1826357 1826566 R hypothetical protein complement(1826357..1826566) Escherichia coli O127:H6 str. E2348/69 7064003 YP_002329282.1 CDS pykF NC_011601.1 1827123 1828535 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1827123..1828535 Escherichia coli O127:H6 str. E2348/69 7064004 YP_002329283.1 CDS lpp NC_011601.1 1828846 1829082 D murein lipoprotein 1828846..1829082 Escherichia coli O127:H6 str. E2348/69 7063928 YP_002329284.1 CDS ynhG NC_011601.1 1829145 1830149 R hypothetical protein complement(1829145..1830149) Escherichia coli O127:H6 str. E2348/69 7061569 YP_002329285.1 CDS sufE NC_011601.1 1830298 1830714 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1830298..1830714) Escherichia coli O127:H6 str. E2348/69 7061191 YP_002329286.1 CDS sufS NC_011601.1 1830727 1831947 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1830727..1831947) Escherichia coli O127:H6 str. E2348/69 7062785 YP_002329287.1 CDS sufD NC_011601.1 1831944 1833215 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1831944..1833215) Escherichia coli O127:H6 str. E2348/69 7061740 YP_002329288.1 CDS sufC NC_011601.1 1833190 1833936 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1833190..1833936) Escherichia coli O127:H6 str. E2348/69 7062784 YP_002329289.1 CDS sufB NC_011601.1 1833946 1835433 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1833946..1835433) Escherichia coli O127:H6 str. E2348/69 7062783 YP_002329290.1 CDS sufA NC_011601.1 1835442 1835810 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1835442..1835810) Escherichia coli O127:H6 str. E2348/69 7062782 YP_002329291.1 CDS ydiH NC_011601.1 1836359 1836547 R hypothetical protein complement(1836359..1836547) Escherichia coli O127:H6 str. E2348/69 7064593 YP_002329292.1 CDS ydiI NC_011601.1 1836647 1837057 R hypothetical protein complement(1836647..1837057) Escherichia coli O127:H6 str. E2348/69 7064009 YP_002329293.1 CDS ydiJ NC_011601.1 1837054 1840110 R FAD-linked oxidoreductase complement(1837054..1840110) Escherichia coli O127:H6 str. E2348/69 7064010 YP_002329294.1 CDS ydiK NC_011601.1 1840499 1841611 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; hypothetical protein 1840499..1841611 Escherichia coli O127:H6 str. E2348/69 7064011 YP_002329295.1 CDS ydiL NC_011601.1 1842040 1842396 D hypothetical protein 1842040..1842396 Escherichia coli O127:H6 str. E2348/69 7061872 YP_002329296.1 CDS ydiM NC_011601.1 1842496 1843710 D transporter 1842496..1843710 Escherichia coli O127:H6 str. E2348/69 7064013 YP_002329297.1 CDS ydiN NC_011601.1 1843937 1845202 D transporter 1843937..1845202 Escherichia coli O127:H6 str. E2348/69 7064014 YP_002329298.1 CDS ydiB NC_011601.1 1845214 1846080 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1845214..1846080 Escherichia coli O127:H6 str. E2348/69 7064015 YP_002329299.1 CDS aroD NC_011601.1 1846111 1846869 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1846111..1846869 Escherichia coli O127:H6 str. E2348/69 7064006 YP_002329300.1 CDS ydiF NC_011601.1 1847014 1848609 D fused acetyl-CoA: acetoacetyl-CoA transferase: alpha subunit/beta subunit 1847014..1848609 Escherichia coli O127:H6 str. E2348/69 7061392 YP_002329301.1 CDS ydiO NC_011601.1 1848623 1849774 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1848623..1849774 Escherichia coli O127:H6 str. E2348/69 7064008 YP_002329302.1 CDS ydiP NC_011601.1 1849817 1850728 R DNA-binding transcriptional regulator complement(1849817..1850728) Escherichia coli O127:H6 str. E2348/69 7064016 YP_002329303.1 CDS ydiQ NC_011601.1 1851044 1851808 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1851044..1851808 Escherichia coli O127:H6 str. E2348/69 7064017 YP_002329304.1 CDS ydiR NC_011601.1 1851828 1852766 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1851828..1852766 Escherichia coli O127:H6 str. E2348/69 7064018 YP_002329305.1 CDS ydiS NC_011601.1 1852821 1854110 D hypothetical protein 1852821..1854110 Escherichia coli O127:H6 str. E2348/69 7064019 YP_002329306.1 CDS ydiT NC_011601.1 1854107 1854400 D 4Fe-4S ferredoxin 1854107..1854400 Escherichia coli O127:H6 str. E2348/69 7064020 YP_002329307.1 CDS fadK NC_011601.1 1854457 1856103 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1854457..1856103 Escherichia coli O127:H6 str. E2348/69 7064021 YP_002329308.1 CDS pps NC_011601.1 1856160 1858538 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1856160..1858538) Escherichia coli O127:H6 str. E2348/69 7062078 YP_002329309.1 CDS ydiA NC_011601.1 1858871 1859704 D hypothetical protein 1858871..1859704 Escherichia coli O127:H6 str. E2348/69 7061276 YP_002329310.1 CDS aroH NC_011601.1 1859861 1860907 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1859861..1860907 Escherichia coli O127:H6 str. E2348/69 7064005 YP_002329311.1 CDS ydiE NC_011601.1 1861039 1861230 D hypothetical protein 1861039..1861230 Escherichia coli O127:H6 str. E2348/69 7061396 YP_002329312.1 CDS ydiU NC_011601.1 1861234 1862670 R hypothetical protein complement(1861234..1862670) Escherichia coli O127:H6 str. E2348/69 7064007 YP_002329313.1 CDS ydiV NC_011601.1 1862733 1863446 R hypothetical protein complement(1862733..1863446) Escherichia coli O127:H6 str. E2348/69 7064022 YP_002329314.1 CDS nlpC NC_011601.1 1863693 1864157 R lipoprotein complement(1863693..1864157) Escherichia coli O127:H6 str. E2348/69 7064023 YP_002329315.1 CDS btuD NC_011601.1 1864235 1864984 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1864235..1864984) Escherichia coli O127:H6 str. E2348/69 7065402 YP_002329316.1 CDS btuE NC_011601.1 1864984 1865535 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(1864984..1865535) Escherichia coli O127:H6 str. E2348/69 7062536 YP_002329317.1 CDS btuC NC_011601.1 1865597 1866577 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1865597..1866577) Escherichia coli O127:H6 str. E2348/69 7062537 YP_002329318.1 CDS E2348C_1797 NC_011601.1 1867173 1868147 R integrase complement(1867173..1868147) Escherichia coli O127:H6 str. E2348/69 7061171 YP_002329319.1 CDS E2348C_1798 NC_011601.1 1868197 1868505 R repressor protein complement(1868197..1868505) Escherichia coli O127:H6 str. E2348/69 7064479 YP_002329320.1 CDS E2348C_1799 NC_011601.1 1868602 1868880 D hypothetical protein 1868602..1868880 Escherichia coli O127:H6 str. E2348/69 7064480 YP_002329321.1 CDS E2348C_1800 NC_011601.1 1868895 1869233 D hypothetical protein 1868895..1869233 Escherichia coli O127:H6 str. E2348/69 7064481 YP_002329322.1 CDS E2348C_1801 NC_011601.1 1869244 1869531 D hypothetical protein 1869244..1869531 Escherichia coli O127:H6 str. E2348/69 7064482 YP_002329323.1 CDS E2348C_1802 NC_011601.1 1869543 1869785 D hypothetical protein 1869543..1869785 Escherichia coli O127:H6 str. E2348/69 7064483 YP_002329324.1 CDS E2348C_1803 NC_011601.1 1869982 1870185 D hypothetical protein 1869982..1870185 Escherichia coli O127:H6 str. E2348/69 7064484 YP_002329325.1 CDS E2348C_1804 NC_011601.1 1870182 1870427 D hypothetical protein 1870182..1870427 Escherichia coli O127:H6 str. E2348/69 7064485 YP_002329326.1 CDS E2348C_1805 NC_011601.1 1870569 1870934 D hypothetical protein 1870569..1870934 Escherichia coli O127:H6 str. E2348/69 7064486 YP_002329327.1 CDS E2348C_1806 NC_011601.1 1871079 1873763 D replication protein 1871079..1873763 Escherichia coli O127:H6 str. E2348/69 7064487 YP_002329328.1 CDS E2348C_1807 NC_011601.1 1873840 1874799 D plasmid partition protein 1873840..1874799 Escherichia coli O127:H6 str. E2348/69 7064488 YP_002329329.1 CDS E2348C_1808 NC_011601.1 1874804 1875115 D plasmid partition protein 1874804..1875115 Escherichia coli O127:H6 str. E2348/69 7064489 YP_002329330.1 CDS E2348C_1809 NC_011601.1 1875494 1876576 D ATPase, AAA-superfamily 1875494..1876576 Escherichia coli O127:H6 str. E2348/69 7064490 YP_002329331.1 CDS E2348C_1810 NC_011601.1 1876573 1878777 D proteases 1876573..1878777 Escherichia coli O127:H6 str. E2348/69 7064491 YP_002329332.1 CDS E2348C_1811 NC_011601.1 1879282 1880328 R capsid portal protein complement(1879282..1880328) Escherichia coli O127:H6 str. E2348/69 7064492 YP_002329333.1 CDS E2348C_1812 NC_011601.1 1880328 1882079 R terminase, ATPase subunit complement(1880328..1882079) Escherichia coli O127:H6 str. E2348/69 7064493 YP_002329334.1 CDS E2348C_1813 NC_011601.1 1882234 1883070 D capsid scaffolding protein 1882234..1883070 Escherichia coli O127:H6 str. E2348/69 7064494 YP_002329335.1 CDS E2348C_1814 NC_011601.1 1883094 1884146 D major capsid protein 1883094..1884146 Escherichia coli O127:H6 str. E2348/69 7064495 YP_002329336.1 CDS E2348C_1815 NC_011601.1 1884192 1884992 D terminase, endonuclease subunit 1884192..1884992 Escherichia coli O127:H6 str. E2348/69 7064496 YP_002329337.1 CDS E2348C_1816 NC_011601.1 1885094 1885588 D capsid completion protein 1885094..1885588 Escherichia coli O127:H6 str. E2348/69 7064497 YP_002329338.1 CDS E2348C_1817 NC_011601.1 1885588 1885788 D tail protein 1885588..1885788 Escherichia coli O127:H6 str. E2348/69 7064498 YP_002329339.1 CDS E2348C_1818 NC_011601.1 1885791 1886114 D holin protein 1885791..1886114 Escherichia coli O127:H6 str. E2348/69 7064499 YP_002329340.1 CDS E2348C_1819 NC_011601.1 1886111 1886503 D endolysin 1886111..1886503 Escherichia coli O127:H6 str. E2348/69 7064500 YP_002329341.1 CDS E2348C_1820 NC_011601.1 1886500 1886907 D hypothetical protein 1886500..1886907 Escherichia coli O127:H6 str. E2348/69 7064501 YP_002329342.1 CDS E2348C_1821 NC_011601.1 1887045 1887512 D tail protein 1887045..1887512 Escherichia coli O127:H6 str. E2348/69 7064502 YP_002329343.1 CDS E2348C_1822 NC_011601.1 1887496 1888140 D tail protein 1887496..1888140 Escherichia coli O127:H6 str. E2348/69 7064503 YP_002329344.1 CDS E2348C_1823 NC_011601.1 1888152 1888718 D baseplate assembly protein 1888152..1888718 Escherichia coli O127:H6 str. E2348/69 7064504 YP_002329345.1 CDS E2348C_1824 NC_011601.1 1888715 1889065 D baseplate assembly protein 1888715..1889065 Escherichia coli O127:H6 str. E2348/69 7064505 YP_002329346.1 CDS E2348C_1825 NC_011601.1 1889069 1889965 D baseplate assembly protein 1889069..1889965 Escherichia coli O127:H6 str. E2348/69 7064506 YP_002329347.1 CDS E2348C_1826 NC_011601.1 1889958 1890566 D tail protein 1889958..1890566 Escherichia coli O127:H6 str. E2348/69 7064507 YP_002329348.1 CDS E2348C_1827 NC_011601.1 1890563 1892128 D tail fiber protein 1890563..1892128 Escherichia coli O127:H6 str. E2348/69 7064508 YP_002329349.1 CDS E2348C_1828 NC_011601.1 1892139 1892615 D alternative C-terminus of phage tail fiber protein, fused to tail fiber protein by inversion 1892139..1892615 Escherichia coli O127:H6 str. E2348/69 7064509 YP_002329350.1 CDS E2348C_1829 NC_011601.1 1892622 1893233 R tail fibre assembly protein complement(1892622..1893233) Escherichia coli O127:H6 str. E2348/69 7064510 YP_002329351.1 CDS E2348C_1830 NC_011601.1 1893233 1893691 R alternative C-terminus of phage tail fiber protein, fused to tail fiber protein by inversion complement(1893233..1893691) Escherichia coli O127:H6 str. E2348/69 7064511 YP_002329352.1 CDS E2348C_1831 NC_011601.1 1893763 1894362 D DNA invertase 1893763..1894362 Escherichia coli O127:H6 str. E2348/69 7064512 YP_002329353.1 CDS E2348C_1832 NC_011601.1 1894389 1894877 R tail assembly protein complement(1894389..1894877) Escherichia coli O127:H6 str. E2348/69 7064513 YP_002329354.1 CDS E2348C_1833 NC_011601.1 1894890 1897697 R phage tail tape measure protein complement(1894890..1897697) Escherichia coli O127:H6 str. E2348/69 7064514 YP_002329355.1 CDS E2348C_1834 NC_011601.1 1897684 1897920 R tail protein complement(1897684..1897920) Escherichia coli O127:H6 str. E2348/69 7064515 YP_002329356.1 CDS E2348C_1835 NC_011601.1 1897848 1898222 R tail protein complement(1897848..1898222) Escherichia coli O127:H6 str. E2348/69 7064516 YP_002329357.1 CDS E2348C_1836 NC_011601.1 1898278 1898790 R tail tube protein complement(1898278..1898790) Escherichia coli O127:H6 str. E2348/69 7064517 YP_002329358.1 CDS E2348C_1837 NC_011601.1 1898790 1899974 R tail sheath protein complement(1898790..1899974) Escherichia coli O127:H6 str. E2348/69 7064518 YP_002329359.1 CDS E2348C_1838 NC_011601.1 1900132 1901232 D late gene regulator 1900132..1901232 Escherichia coli O127:H6 str. E2348/69 7064519 YP_002329360.1 CDS E2348C_1839 NC_011601.1 1901427 1902092 D hypothetical protein 1901427..1902092 Escherichia coli O127:H6 str. E2348/69 7064520 YP_002329361.1 CDS E2348C_1840 NC_011601.1 1902242 1902502 D regulatory protein 1902242..1902502 Escherichia coli O127:H6 str. E2348/69 7064521 YP_002329362.1 CDS ihfA NC_011601.1 1903137 1903436 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1903137..1903436) Escherichia coli O127:H6 str. E2348/69 7064522 YP_002329363.1 CDS pheT NC_011601.1 1903441 1905828 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1903441..1905828) Escherichia coli O127:H6 str. E2348/69 7063520 YP_002329364.1 CDS pheS NC_011601.1 1905843 1906826 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1905843..1906826) Escherichia coli O127:H6 str. E2348/69 7060725 YP_002329366.1 CDS rplT NC_011601.1 1907277 1907633 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1907277..1907633) Escherichia coli O127:H6 str. E2348/69 7060722 YP_002329367.1 CDS rpmI NC_011601.1 1907686 1907883 R 50S ribosomal protein L35 complement(1907686..1907883) Escherichia coli O127:H6 str. E2348/69 7061847 YP_002329368.1 CDS infC NC_011601.1 1907980 1908522 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1907980..1908522) Escherichia coli O127:H6 str. E2348/69 7061861 YP_002329369.1 CDS thrS NC_011601.1 1908526 1910454 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1908526..1910454) Escherichia coli O127:H6 str. E2348/69 7063544 YP_002329370.1 CDS yniD NC_011601.1 1912165 1912272 D hypothetical protein 1912165..1912272 Escherichia coli O127:H6 str. E2348/69 7064523 YP_002329371.1 CDS ydiY NC_011601.1 1912325 1913083 R hypothetical protein complement(1912325..1913083) Escherichia coli O127:H6 str. E2348/69 7061195 YP_002329372.1 CDS pfkB NC_011601.1 1913370 1914299 D 6-phosphofructokinase 1913370..1914299 Escherichia coli O127:H6 str. E2348/69 7064024 YP_002329373.1 CDS ydiZ NC_011601.1 1914400 1914690 D hypothetical protein 1914400..1914690 Escherichia coli O127:H6 str. E2348/69 7060707 YP_002329374.1 CDS yniA NC_011601.1 1914796 1915656 D phosphotransferase/kinase 1914796..1915656 Escherichia coli O127:H6 str. E2348/69 7064025 YP_002329375.1 CDS yniB NC_011601.1 1915697 1916233 R hypothetical protein complement(1915697..1916233) Escherichia coli O127:H6 str. E2348/69 7061192 YP_002329376.1 CDS yniC NC_011601.1 1916380 1917048 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1916380..1917048 Escherichia coli O127:H6 str. E2348/69 7061193 YP_002329377.1 CDS ydjM NC_011601.1 1917211 1917801 D hypothetical protein 1917211..1917801 Escherichia coli O127:H6 str. E2348/69 7061194 YP_002329378.1 CDS ydjN NC_011601.1 1917934 1919325 D transporter 1917934..1919325 Escherichia coli O127:H6 str. E2348/69 7064035 YP_002329379.1 CDS cedA NC_011601.1 1919372 1919635 R cell division modulator complement(1919372..1919635) Escherichia coli O127:H6 str. E2348/69 7064036 YP_002329380.1 CDS katE NC_011601.1 1919818 1922079 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1919818..1922079 Escherichia coli O127:H6 str. E2348/69 7064344 YP_002329381.1 CDS chbG NC_011601.1 1922125 1922883 R hypothetical protein complement(1922125..1922883) Escherichia coli O127:H6 str. E2348/69 7063563 YP_002329382.1 CDS chbF NC_011601.1 1922896 1924248 R cryptic phospho-beta-glucosidase, NAD(P)-binding complement(1922896..1924248) Escherichia coli O127:H6 str. E2348/69 7064357 YP_002329383.1 CDS chbR NC_011601.1 1924352 1925194 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1924352..1925194) Escherichia coli O127:H6 str. E2348/69 7064356 YP_002329384.1 CDS chbA NC_011601.1 1925202 1925552 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1925202..1925552) Escherichia coli O127:H6 str. E2348/69 7064358 YP_002329385.1 CDS chbC NC_011601.1 1925603 1926961 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1925603..1926961) Escherichia coli O127:H6 str. E2348/69 7064353 YP_002329386.1 CDS chbB NC_011601.1 1927046 1927366 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1927046..1927366) Escherichia coli O127:H6 str. E2348/69 7064355 YP_002329387.1 CDS osmE NC_011601.1 1927666 1928004 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1927666..1928004) Escherichia coli O127:H6 str. E2348/69 7064354 YP_002329388.1 CDS nadE NC_011601.1 1928206 1929033 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1928206..1929033 Escherichia coli O127:H6 str. E2348/69 7062891 YP_002329389.1 CDS cho NC_011601.1 1929263 1930150 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1929263..1930150 Escherichia coli O127:H6 str. E2348/69 7060908 YP_002329390.1 CDS vse NC_011601.1 1930110 1930685 R hypothetical protein complement(1930110..1930685) Escherichia coli O127:H6 str. E2348/69 7064365 YP_002329391.1 CDS spy NC_011601.1 1930888 1931373 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(1930888..1931373) Escherichia coli O127:H6 str. E2348/69 7062362 YP_002329392.1 CDS astE NC_011601.1 1931703 1932671 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1931703..1932671) Escherichia coli O127:H6 str. E2348/69 7062752 YP_002329393.1 CDS astB NC_011601.1 1932664 1934007 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1932664..1934007) Escherichia coli O127:H6 str. E2348/69 7062469 YP_002329394.1 CDS astD NC_011601.1 1934004 1935482 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1934004..1935482) Escherichia coli O127:H6 str. E2348/69 7062466 YP_002329395.1 CDS astA NC_011601.1 1935479 1936513 R arginine succinyltransferase complement(1935479..1936513) Escherichia coli O127:H6 str. E2348/69 7062468 YP_002329396.1 CDS astC NC_011601.1 1936510 1937730 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1936510..1937730) Escherichia coli O127:H6 str. E2348/69 7062465 YP_002329397.1 CDS xthA NC_011601.1 1938176 1938982 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1938176..1938982 Escherichia coli O127:H6 str. E2348/69 7062467 YP_002329398.1 CDS ydjX NC_011601.1 1939149 1939859 D hypothetical protein 1939149..1939859 Escherichia coli O127:H6 str. E2348/69 7064868 YP_002329399.1 CDS ydjY NC_011601.1 1939864 1940541 D hypothetical protein 1939864..1940541 Escherichia coli O127:H6 str. E2348/69 7064037 YP_002329400.1 CDS ydjZ NC_011601.1 1940558 1941262 D hypothetical protein 1940558..1941262 Escherichia coli O127:H6 str. E2348/69 7064038 YP_002329401.1 CDS ynjA NC_011601.1 1941262 1941810 D hypothetical protein 1941262..1941810 Escherichia coli O127:H6 str. E2348/69 7064039 YP_002329402.1 CDS ynjB NC_011601.1 1941820 1942986 D ABC transporter substrate-binding protein 1941820..1942986 Escherichia coli O127:H6 str. E2348/69 7061196 YP_002329403.1 CDS ynjC NC_011601.1 1942959 1944494 D fused transporter subunits of ABC superfamily: membrane components 1942959..1944494 Escherichia coli O127:H6 str. E2348/69 7061197 YP_002329404.1 CDS ynjD NC_011601.1 1944494 1945147 D transporter subunit: ATP-binding component of ABC superfamily 1944494..1945147 Escherichia coli O127:H6 str. E2348/69 7061198 YP_002329405.1 CDS ynjE NC_011601.1 1945214 1946521 D thiosulfate sulfur transferase 1945214..1946521 Escherichia coli O127:H6 str. E2348/69 7061199 YP_002329406.1 CDS ynjF NC_011601.1 1946530 1947150 R phosphatidyl transferase, inner membrane protein complement(1946530..1947150) Escherichia coli O127:H6 str. E2348/69 7061200 YP_002329407.1 CDS nudG NC_011601.1 1947237 1947644 D pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1947237..1947644 Escherichia coli O127:H6 str. E2348/69 7061201 YP_002329408.1 CDS ynjH NC_011601.1 1947610 1947882 R hypothetical protein complement(1947610..1947882) Escherichia coli O127:H6 str. E2348/69 7065431 YP_002329409.1 CDS gdhA NC_011601.1 1948118 1949461 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1948118..1949461 Escherichia coli O127:H6 str. E2348/69 7061202 YP_002329410.1 CDS topB NC_011601.1 1949538 1951493 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1949538..1951493) Escherichia coli O127:H6 str. E2348/69 7061647 YP_002329411.1 CDS selD NC_011601.1 1951498 1952541 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1951498..1952541) Escherichia coli O127:H6 str. E2348/69 7062219 YP_002329412.1 CDS ydjA NC_011601.1 1952658 1953209 R hypothetical protein complement(1952658..1953209) Escherichia coli O127:H6 str. E2348/69 7065362 YP_002329413.1 CDS sppA NC_011601.1 1953370 1955226 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1953370..1955226 Escherichia coli O127:H6 str. E2348/69 7064026 YP_002329414.1 CDS ansA NC_011601.1 1955391 1956407 D converts asparagine to aspartate and ammonia; asparaginase 1955391..1956407 Escherichia coli O127:H6 str. E2348/69 7062750 YP_002329415.1 CDS pncA NC_011601.1 1956418 1957059 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1956418..1957059 Escherichia coli O127:H6 str. E2348/69 7061344 YP_002329416.1 CDS ydjE NC_011601.1 1957152 1958510 R transporter complement(1957152..1958510) Escherichia coli O127:H6 str. E2348/69 7060761 YP_002329417.1 CDS ydjF NC_011601.1 1958628 1959386 R DNA-binding transcriptional regulator complement(1958628..1959386) Escherichia coli O127:H6 str. E2348/69 7064027 YP_002329418.1 CDS ydjG NC_011601.1 1959523 1960503 R oxidoreductase complement(1959523..1960503) Escherichia coli O127:H6 str. E2348/69 7064028 YP_002329419.1 CDS ydjH NC_011601.1 1960513 1961460 R kinase complement(1960513..1961460) Escherichia coli O127:H6 str. E2348/69 7064029 YP_002329420.1 CDS ydjI NC_011601.1 1961465 1962301 R aldolase complement(1961465..1962301) Escherichia coli O127:H6 str. E2348/69 7064030 YP_002329421.1 CDS ydjJ NC_011601.1 1962322 1963365 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(1962322..1963365) Escherichia coli O127:H6 str. E2348/69 7064031 YP_002329422.1 CDS ydjK NC_011601.1 1963382 1964761 R transporter complement(1963382..1964761) Escherichia coli O127:H6 str. E2348/69 7064032 YP_002329423.1 CDS ydjL NC_011601.1 1964788 1965864 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(1964788..1965864) Escherichia coli O127:H6 str. E2348/69 7064033 YP_002329424.1 CDS yeaC NC_011601.1 1966234 1966506 R hypothetical protein complement(1966234..1966506) Escherichia coli O127:H6 str. E2348/69 7064034 YP_002329425.1 CDS msrB NC_011601.1 1966548 1966961 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1966548..1966961) Escherichia coli O127:H6 str. E2348/69 7064040 YP_002329426.1 CDS gapA NC_011601.1 1967303 1968298 D glyceraldehyde-3-phosphate dehydrogenase 1967303..1968298 Escherichia coli O127:H6 str. E2348/69 7060875 YP_002329427.1 CDS yeaD NC_011601.1 1968382 1969266 D hypothetical protein 1968382..1969266 Escherichia coli O127:H6 str. E2348/69 7061625 YP_002329428.1 CDS yeaE NC_011601.1 1969317 1970171 R oxidoreductase complement(1969317..1970171) Escherichia coli O127:H6 str. E2348/69 7064041 YP_002329429.1 CDS mipA NC_011601.1 1970261 1971007 R scaffolding protein for murein synthesizing machinery complement(1970261..1971007) Escherichia coli O127:H6 str. E2348/69 7064042 YP_002329430.1 CDS yeaG NC_011601.1 1971443 1973377 D hypothetical protein 1971443..1973377 Escherichia coli O127:H6 str. E2348/69 7063792 YP_002329431.1 CDS yeaH NC_011601.1 1973490 1974773 D hypothetical protein 1973490..1974773 Escherichia coli O127:H6 str. E2348/69 7064043 YP_002329432.1 CDS yeaI NC_011601.1 1975052 1976395 D diguanylate cyclase 1975052..1976395 Escherichia coli O127:H6 str. E2348/69 7064044 YP_002329433.1 CDS yeaJ NC_011601.1 1976576 1978066 D diguanylate cyclase 1976576..1978066 Escherichia coli O127:H6 str. E2348/69 7064045 YP_002329434.1 CDS yeaK NC_011601.1 1978109 1978612 D hypothetical protein 1978109..1978612 Escherichia coli O127:H6 str. E2348/69 7064046 YP_002329435.1 CDS yoaI NC_011601.1 1978613 1978717 R hypothetical protein complement(1978613..1978717) Escherichia coli O127:H6 str. E2348/69 7064047 YP_002329436.1 CDS yeaL NC_011601.1 1978887 1979333 D hypothetical protein 1978887..1979333 Escherichia coli O127:H6 str. E2348/69 7061211 YP_002329437.1 CDS yeaM NC_011601.1 1979290 1980111 R DNA-binding transcriptional regulator, ARAC-type complement(1979290..1980111) Escherichia coli O127:H6 str. E2348/69 7064048 YP_002329438.1 CDS yeaN NC_011601.1 1980208 1981389 D transporter 1980208..1981389 Escherichia coli O127:H6 str. E2348/69 7064049 YP_002329439.1 CDS yeaO NC_011601.1 1981444 1981791 D hypothetical protein 1981444..1981791 Escherichia coli O127:H6 str. E2348/69 7064050 YP_002329440.1 CDS yoaF NC_011601.1 1981813 1982067 R hypothetical protein complement(1981813..1982067) Escherichia coli O127:H6 str. E2348/69 7064051 YP_002329441.1 CDS yeaP NC_011601.1 1982250 1983275 D diguanylate cyclase 1982250..1983275 Escherichia coli O127:H6 str. E2348/69 7061208 YP_002329442.1 CDS yeaQ NC_011601.1 1983543 1983791 R hypothetical protein complement(1983543..1983791) Escherichia coli O127:H6 str. E2348/69 7064052 YP_002329443.1 CDS yoaG NC_011601.1 1983939 1984121 R hypothetical protein complement(1983939..1984121) Escherichia coli O127:H6 str. E2348/69 7064053 YP_002329444.1 CDS yeaR NC_011601.1 1984125 1984484 R hypothetical protein complement(1984125..1984484) Escherichia coli O127:H6 str. E2348/69 7061209 YP_002329445.1 CDS leuE NC_011601.1 1984656 1985294 R leucine export protein LeuE complement(1984656..1985294) Escherichia coli O127:H6 str. E2348/69 7064054 YP_002329446.1 CDS rnd NC_011601.1 1985837 1986964 R ribonuclease D complement(1985837..1986964) Escherichia coli O127:H6 str. E2348/69 7064055 YP_002329447.1 CDS fadD NC_011601.1 1987034 1988719 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1987034..1988719) Escherichia coli O127:H6 str. E2348/69 7062757 YP_002329448.1 CDS yeaY NC_011601.1 1988924 1989505 R lipoprotein complement(1988924..1989505) Escherichia coli O127:H6 str. E2348/69 7062073 YP_002329449.1 CDS yeaZ NC_011601.1 1989545 1990240 R peptidase complement(1989545..1990240) Escherichia coli O127:H6 str. E2348/69 7064056 YP_002329450.1 CDS yoaA NC_011601.1 1990298 1992208 R hypothetical protein complement(1990298..1992208) Escherichia coli O127:H6 str. E2348/69 7064057 YP_002329451.1 CDS yoaB NC_011601.1 1992337 1992684 D hypothetical protein 1992337..1992684 Escherichia coli O127:H6 str. E2348/69 7061203 YP_002329452.1 CDS yoaC NC_011601.1 1993106 1993405 D hypothetical protein 1993106..1993405 Escherichia coli O127:H6 str. E2348/69 7061204 YP_002329453.1 CDS yoaH NC_011601.1 1993525 1993704 R hypothetical protein complement(1993525..1993704) Escherichia coli O127:H6 str. E2348/69 7061205 YP_002329454.1 CDS pabB NC_011601.1 1993778 1995139 D aminodeoxychorismate synthase subunit I 1993778..1995139 Escherichia coli O127:H6 str. E2348/69 7061210 YP_002329455.1 CDS nudL NC_011601.1 1995143 1995721 D hypothetical protein 1995143..1995721 Escherichia coli O127:H6 str. E2348/69 7062901 YP_002329456.1 CDS sdaA NC_011601.1 1995905 1997269 D L-serine deaminase I 1995905..1997269 Escherichia coli O127:H6 str. E2348/69 7065436 YP_002329457.1 CDS yoaD NC_011601.1 1997400 1998998 D phosphodiesterase 1997400..1998998 Escherichia coli O127:H6 str. E2348/69 7065344 YP_002329458.1 CDS yoaE NC_011601.1 1999002 2000558 R fused membrane protein/conserved protein complement(1999002..2000558) Escherichia coli O127:H6 str. E2348/69 7061206 YP_002329459.1 CDS E2348C_1940 NC_011601.1 2000546 2000755 R hypothetical protein complement(2000546..2000755) Escherichia coli O127:H6 str. E2348/69 7061207 YP_002329460.1 CDS manX NC_011601.1 2001021 2001992 D fused mannose-specific PTS enzymes: IIA and IIB component 2001021..2001992 Escherichia coli O127:H6 str. E2348/69 7064524 YP_002329461.1 CDS manY NC_011601.1 2002055 2002855 D mannose-specific enzyme IIC component of PTS 2002055..2002855 Escherichia coli O127:H6 str. E2348/69 7065286 YP_002329462.1 CDS manZ NC_011601.1 2002859 2003719 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2002859..2003719 Escherichia coli O127:H6 str. E2348/69 7065287 YP_002329463.1 CDS yobD NC_011601.1 2003774 2004232 D hypothetical protein 2003774..2004232 Escherichia coli O127:H6 str. E2348/69 7065288 YP_002329464.1 CDS yebN NC_011601.1 2004661 2005227 D membrane protein YebN; hypothetical protein 2004661..2005227 Escherichia coli O127:H6 str. E2348/69 7061147 YP_002329465.1 CDS rrmA NC_011601.1 2005224 2006033 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase complement(2005224..2006033) Escherichia coli O127:H6 str. E2348/69 7064065 YP_002329466.1 CDS cspC NC_011601.1 2006199 2006408 R cold shock-like protein CspC complement(2006199..2006408) Escherichia coli O127:H6 str. E2348/69 7064540 YP_002329467.1 CDS yobF NC_011601.1 2006421 2006564 R hypothetical protein complement(2006421..2006564) Escherichia coli O127:H6 str. E2348/69 7062861 YP_002329468.1 CDS yebO NC_011601.1 2007235 2007522 R hypothetical protein complement(2007235..2007522) Escherichia coli O127:H6 str. E2348/69 7061215 YP_002329469.1 CDS mgrB NC_011601.1 2007597 2007740 R hypothetical protein complement(2007597..2007740) Escherichia coli O127:H6 str. E2348/69 7064066 YP_002329470.1 CDS yobH NC_011601.1 2007899 2008138 D hypothetical protein 2007899..2008138 Escherichia coli O127:H6 str. E2348/69 7063780 YP_002329471.1 CDS kdgR NC_011601.1 2008282 2009073 R DNA-binding transcriptional regulator complement(2008282..2009073) Escherichia coli O127:H6 str. E2348/69 7061216 YP_002329472.1 CDS yebQ NC_011601.1 2009250 2010623 D transporter 2009250..2010623 Escherichia coli O127:H6 str. E2348/69 7063570 YP_002329473.1 CDS htpX NC_011601.1 2010669 2011550 R metalloprotease; heat shock protein HtpX complement(2010669..2011550) Escherichia coli O127:H6 str. E2348/69 7064067 YP_002329474.1 CDS prc NC_011601.1 2011742 2013790 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2011742..2013790) Escherichia coli O127:H6 str. E2348/69 7062190 YP_002329475.1 CDS proQ NC_011601.1 2013810 2014508 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(2013810..2014508) Escherichia coli O127:H6 str. E2348/69 7061283 YP_002329476.1 CDS yebR NC_011601.1 2014605 2015156 R hypothetical protein complement(2014605..2015156) Escherichia coli O127:H6 str. E2348/69 7061303 YP_002329477.1 CDS yebS NC_011601.1 2015232 2016515 D hypothetical protein 2015232..2016515 Escherichia coli O127:H6 str. E2348/69 7062947 YP_002329478.1 CDS yebT NC_011601.1 2016484 2019117 D hypothetical protein 2016484..2019117 Escherichia coli O127:H6 str. E2348/69 7063027 YP_002329479.1 CDS yebU NC_011601.1 2019197 2020636 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2019197..2020636 Escherichia coli O127:H6 str. E2348/69 7063028 YP_002329480.1 CDS yebV NC_011601.1 2020754 2020990 D hypothetical protein 2020754..2020990 Escherichia coli O127:H6 str. E2348/69 7064559 YP_002329481.1 CDS yebW NC_011601.1 2021011 2021286 D hypothetical protein 2021011..2021286 Escherichia coli O127:H6 str. E2348/69 7063029 YP_002329482.1 CDS pphA NC_011601.1 2021287 2021943 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2021287..2021943) Escherichia coli O127:H6 str. E2348/69 7063030 YP_002329483.1 CDS yebY NC_011601.1 2022338 2022679 R hypothetical protein complement(2022338..2022679) Escherichia coli O127:H6 str. E2348/69 7064596 YP_002329484.1 CDS yebZ NC_011601.1 2022692 2023564 R hypothetical protein complement(2022692..2023564) Escherichia coli O127:H6 str. E2348/69 7063031 YP_002329485.1 CDS yobA NC_011601.1 2023568 2023942 R hypothetical protein complement(2023568..2023942) Escherichia coli O127:H6 str. E2348/69 7063032 YP_002329486.1 CDS holE NC_011601.1 2024081 2024311 D DNA polymerase III subunit theta 2024081..2024311 Escherichia coli O127:H6 str. E2348/69 7061212 YP_002329487.1 CDS yobB NC_011601.1 2024413 2025069 D hypothetical protein 2024413..2025069 Escherichia coli O127:H6 str. E2348/69 7062175 YP_002329488.1 CDS exoX NC_011601.1 2025093 2025755 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2025093..2025755 Escherichia coli O127:H6 str. E2348/69 7061213 YP_002329489.1 CDS ptrB NC_011601.1 2025752 2027812 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(2025752..2027812) Escherichia coli O127:H6 str. E2348/69 7063907 YP_002329490.1 CDS yebE NC_011601.1 2028019 2028678 R hypothetical protein complement(2028019..2028678) Escherichia coli O127:H6 str. E2348/69 7061336 YP_002329491.1 CDS yebF NC_011601.1 2029005 2029361 R secreted protein; unknown function; hypothetical protein complement(2029005..2029361) Escherichia coli O127:H6 str. E2348/69 7064061 YP_002329492.1 CDS yebG NC_011601.1 2029428 2029718 R DNA damage-inducible protein YebG complement(2029428..2029718) Escherichia coli O127:H6 str. E2348/69 7064062 YP_002329493.1 CDS purT NC_011601.1 2029852 2031030 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2029852..2031030 Escherichia coli O127:H6 str. E2348/69 7064063 YP_002329494.1 CDS eda NC_011601.1 2031086 2031727 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2031086..2031727) Escherichia coli O127:H6 str. E2348/69 7063923 YP_002329495.1 CDS edd NC_011601.1 2031764 2033575 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2031764..2033575) Escherichia coli O127:H6 str. E2348/69 7063837 YP_002329496.1 CDS zwf NC_011601.1 2033810 2035285 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2033810..2035285) Escherichia coli O127:H6 str. E2348/69 7063838 YP_002329497.1 CDS yebK NC_011601.1 2035623 2036492 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2035623..2036492 Escherichia coli O127:H6 str. E2348/69 7062543 YP_002329498.1 CDS pykA NC_011601.1 2036620 2038062 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2036620..2038062 Escherichia coli O127:H6 str. E2348/69 7064064 YP_002329499.1 CDS lpxM NC_011601.1 2038194 2039165 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2038194..2039165) Escherichia coli O127:H6 str. E2348/69 7063927 YP_002329500.1 CDS yebA NC_011601.1 2039284 2040606 R hypothetical protein complement(2039284..2040606) Escherichia coli O127:H6 str. E2348/69 7061579 YP_002329501.1 CDS znuA NC_011601.1 2040622 2041554 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(2040622..2041554) Escherichia coli O127:H6 str. E2348/69 7064058 YP_002329502.1 CDS znuC NC_011601.1 2041633 2042388 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2041633..2042388 Escherichia coli O127:H6 str. E2348/69 7063262 YP_002329503.1 CDS znuB NC_011601.1 2042385 2043170 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2042385..2043170 Escherichia coli O127:H6 str. E2348/69 7061098 YP_002329504.1 CDS ruvB NC_011601.1 2043317 2044327 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2043317..2044327) Escherichia coli O127:H6 str. E2348/69 7063263 YP_002329505.1 CDS ruvA NC_011601.1 2044336 2044947 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2044336..2044947) Escherichia coli O127:H6 str. E2348/69 7064589 YP_002329506.1 CDS yebB NC_011601.1 2045223 2045825 D hypothetical protein 2045223..2045825 Escherichia coli O127:H6 str. E2348/69 7064588 YP_002329507.1 CDS ruvC NC_011601.1 2045827 2046348 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2045827..2046348) Escherichia coli O127:H6 str. E2348/69 7064059 YP_002329508.1 CDS yebC NC_011601.1 2046383 2047123 R hypothetical protein complement(2046383..2047123) Escherichia coli O127:H6 str. E2348/69 7064590 YP_002329509.1 CDS ntpA NC_011601.1 2047152 2047595 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2047152..2047595) Escherichia coli O127:H6 str. E2348/69 7064060 YP_002329510.1 CDS aspS NC_011601.1 2047597 2049369 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2047597..2049369) Escherichia coli O127:H6 str. E2348/69 7065427 YP_002329511.1 CDS yecD NC_011601.1 2049679 2050245 D hypothetical protein 2049679..2050245 Escherichia coli O127:H6 str. E2348/69 7062460 YP_002329512.1 CDS yecE NC_011601.1 2050242 2051060 D hypothetical protein 2050242..2051060 Escherichia coli O127:H6 str. E2348/69 7063035 YP_002329513.1 CDS yecN NC_011601.1 2051113 2051508 D hypothetical protein 2051113..2051508 Escherichia coli O127:H6 str. E2348/69 7063036 YP_002329514.1 CDS cmoA NC_011601.1 2051549 2052292 D methyltransferase 2051549..2052292 Escherichia coli O127:H6 str. E2348/69 7063041 YP_002329515.1 CDS cmoB NC_011601.1 2052289 2053260 D S-adenosyl-L-methionine-dependent methyltransferase 2052289..2053260 Escherichia coli O127:H6 str. E2348/69 7062815 YP_002329516.1 CDS torZ NC_011601.1 2053425 2055854 R trimethylamine N-oxide reductase system III, catalytic subunit complement(2053425..2055854) Escherichia coli O127:H6 str. E2348/69 7062816 YP_002329517.1 CDS torY NC_011601.1 2055879 2056979 R TMAO reductase III (TorYZ), cytochrome c-type subunit complement(2055879..2056979) Escherichia coli O127:H6 str. E2348/69 7062228 YP_002329518.1 CDS cutC NC_011601.1 2057367 2058113 R copper homeostasis protein CutC complement(2057367..2058113) Escherichia coli O127:H6 str. E2348/69 7062227 YP_002329519.1 CDS yecM NC_011601.1 2058127 2058693 R hypothetical protein complement(2058127..2058693) Escherichia coli O127:H6 str. E2348/69 7065176 YP_002329520.1 CDS argS NC_011601.1 2058909 2060642 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2058909..2060642 Escherichia coli O127:H6 str. E2348/69 7063040 YP_002329521.1 CDS flhE NC_011601.1 2060695 2061087 R hypothetical protein complement(2060695..2061087) Escherichia coli O127:H6 str. E2348/69 7061377 YP_002329522.1 CDS flhA NC_011601.1 2061087 2063165 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2061087..2063165) Escherichia coli O127:H6 str. E2348/69 7061912 YP_002329523.1 CDS flhB NC_011601.1 2063158 2064306 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2063158..2064306) Escherichia coli O127:H6 str. E2348/69 7061908 YP_002329524.1 CDS cheZ NC_011601.1 2064495 2065139 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2064495..2065139) Escherichia coli O127:H6 str. E2348/69 7061909 YP_002329525.1 CDS cheY NC_011601.1 2065150 2065539 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2065150..2065539) Escherichia coli O127:H6 str. E2348/69 7064364 YP_002329526.1 CDS cheB NC_011601.1 2065554 2066603 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2065554..2066603) Escherichia coli O127:H6 str. E2348/69 7064363 YP_002329527.1 CDS cheR NC_011601.1 2066606 2067466 R methylates the MCP; chemotaxis methyltransferase CheR complement(2066606..2067466) Escherichia coli O127:H6 str. E2348/69 7064360 YP_002329528.1 CDS tar NC_011601.1 2067757 2069418 R methyl-accepting chemotaxis protein II complement(2067757..2069418) Escherichia coli O127:H6 str. E2348/69 7064361 YP_002329529.1 CDS cheW NC_011601.1 2069563 2070066 R purine-binding chemotaxis protein complement(2069563..2070066) Escherichia coli O127:H6 str. E2348/69 7061148 YP_002329530.1 CDS cheA NC_011601.1 2070087 2072051 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(2070087..2072051) Escherichia coli O127:H6 str. E2348/69 7064362 YP_002329531.1 CDS motB NC_011601.1 2072056 2072982 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2072056..2072982) Escherichia coli O127:H6 str. E2348/69 7064359 YP_002329532.1 CDS motA NC_011601.1 2072979 2073866 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2072979..2073866) Escherichia coli O127:H6 str. E2348/69 7063822 YP_002329533.1 CDS flhC NC_011601.1 2073993 2074571 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2073993..2074571) Escherichia coli O127:H6 str. E2348/69 7063821 YP_002329534.1 CDS flhD NC_011601.1 2074574 2074924 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2074574..2074924) Escherichia coli O127:H6 str. E2348/69 7061910 YP_002329535.1 CDS uspC NC_011601.1 2075704 2076132 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2075704..2076132 Escherichia coli O127:H6 str. E2348/69 7061911 YP_002329536.1 CDS otsA NC_011601.1 2076139 2077563 R trehalose-6-phosphate synthase complement(2076139..2077563) Escherichia coli O127:H6 str. E2348/69 7062334 YP_002329537.1 CDS otsB NC_011601.1 2077538 2078338 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2077538..2078338) Escherichia coli O127:H6 str. E2348/69 7062894 YP_002329538.1 CDS E2348C_2020 NC_011601.1 2078901 2080274 R transposase of ISEc13 complement(2078901..2080274) Escherichia coli O127:H6 str. E2348/69 7064229 YP_002329539.1 CDS araG NC_011601.1 2081065 2082579 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2081065..2082579) Escherichia coli O127:H6 str. E2348/69 7064525 YP_002329540.1 CDS araF NC_011601.1 2082649 2083638 R L-arabinose transporter subunit complement(2082649..2083638) Escherichia coli O127:H6 str. E2348/69 7061361 YP_002329541.1 CDS ftnB NC_011601.1 2084435 2084938 D ferritin 2084435..2084938 Escherichia coli O127:H6 str. E2348/69 7061360 YP_002329542.1 CDS yecJ NC_011601.1 2085017 2085268 R hypothetical protein complement(2085017..2085268) Escherichia coli O127:H6 str. E2348/69 7061580 YP_002329543.1 CDS yecR NC_011601.1 2085732 2086055 D hypothetical protein 2085732..2086055 Escherichia coli O127:H6 str. E2348/69 7063560 YP_002329544.1 CDS ftnA NC_011601.1 2086227 2086724 D cytoplasmic iron storage protein; ferritin 2086227..2086724 Escherichia coli O127:H6 str. E2348/69 7063042 YP_002329545.1 CDS yecH NC_011601.1 2086762 2087001 R hypothetical protein complement(2086762..2087001) Escherichia coli O127:H6 str. E2348/69 7062058 YP_002329546.1 CDS tyrP NC_011601.1 2087192 2088403 D tyrosine transporter 2087192..2088403 Escherichia coli O127:H6 str. E2348/69 7063038 YP_002329547.1 CDS yecA NC_011601.1 2088465 2089130 R hypothetical protein complement(2088465..2089130) Escherichia coli O127:H6 str. E2348/69 7062285 YP_002329548.1 CDS pgsA NC_011601.1 2089779 2090327 R phosphatidylglycerophosphate synthetase complement(2089779..2090327) Escherichia coli O127:H6 str. E2348/69 7061726 YP_002329549.1 CDS uvrC NC_011601.1 2090384 2092216 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2090384..2092216) Escherichia coli O127:H6 str. E2348/69 7060719 YP_002329550.1 CDS uvrY NC_011601.1 2092213 2092869 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2092213..2092869) Escherichia coli O127:H6 str. E2348/69 7062342 YP_002329551.1 CDS yecF NC_011601.1 2093328 2093552 D hypothetical protein 2093328..2093552 Escherichia coli O127:H6 str. E2348/69 7062344 YP_002329552.1 CDS sdiA NC_011601.1 2093620 2094342 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2093620..2094342) Escherichia coli O127:H6 str. E2348/69 7063037 YP_002329553.1 CDS yecC NC_011601.1 2094572 2095324 R amino-acid ABC transporter ATP-binding protein YecC complement(2094572..2095324) Escherichia coli O127:H6 str. E2348/69 7065351 YP_002329554.1 CDS yecS NC_011601.1 2095321 2095989 R transporter subunit: membrane component of ABC superfamily complement(2095321..2095989) Escherichia coli O127:H6 str. E2348/69 7063034 YP_002329555.1 CDS dcyD NC_011601.1 2096004 2096990 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2096004..2096990) Escherichia coli O127:H6 str. E2348/69 7063043 YP_002329556.1 CDS fliY NC_011601.1 2097095 2097895 R cystine transporter subunit complement(2097095..2097895) Escherichia coli O127:H6 str. E2348/69 7065236 YP_002329557.1 CDS fliZ NC_011601.1 2097983 2098534 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2097983..2098534) Escherichia coli O127:H6 str. E2348/69 7061932 YP_002329558.1 CDS fliA NC_011601.1 2098580 2099299 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2098580..2099299) Escherichia coli O127:H6 str. E2348/69 7061933 YP_002329559.1 CDS fliC NC_011601.1 2099620 2101266 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2099620..2101266) Escherichia coli O127:H6 str. E2348/69 7061913 YP_002329560.1 CDS fliD NC_011601.1 2101532 2102938 D involved in flagellin assembly; flagellar capping protein 2101532..2102938 Escherichia coli O127:H6 str. E2348/69 7061914 YP_002329561.1 CDS fliS NC_011601.1 2102963 2103373 D flagellin specific chaperone; flagellar protein FliS 2102963..2103373 Escherichia coli O127:H6 str. E2348/69 7061915 YP_002329562.1 CDS fliT NC_011601.1 2103373 2103738 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2103373..2103738 Escherichia coli O127:H6 str. E2348/69 7061930 YP_002329563.1 CDS amyA NC_011601.1 2103816 2105303 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2103816..2105303 Escherichia coli O127:H6 str. E2348/69 7061931 YP_002329564.1 CDS yedE NC_011601.1 2105936 2107141 D hypothetical protein 2105936..2107141 Escherichia coli O127:H6 str. E2348/69 7063045 YP_002329565.1 CDS yedF NC_011601.1 2107138 2107371 D hypothetical protein 2107138..2107371 Escherichia coli O127:H6 str. E2348/69 7063046 YP_002329566.1 CDS yedK NC_011601.1 2107480 2108148 D hypothetical protein 2107480..2108148 Escherichia coli O127:H6 str. E2348/69 7063047 YP_002329567.1 CDS yedL NC_011601.1 2108259 2108738 D acyltransferase 2108259..2108738 Escherichia coli O127:H6 str. E2348/69 7063050 YP_002329568.1 CDS fliE NC_011601.1 2109143 2109457 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2109143..2109457) Escherichia coli O127:H6 str. E2348/69 7063051 YP_002329569.1 CDS fliF NC_011601.1 2109672 2111330 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2109672..2111330 Escherichia coli O127:H6 str. E2348/69 7061916 YP_002329570.1 CDS fliG NC_011601.1 2111323 2112318 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2111323..2112318 Escherichia coli O127:H6 str. E2348/69 7061917 YP_002329571.1 CDS fliH NC_011601.1 2112311 2112997 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2112311..2112997 Escherichia coli O127:H6 str. E2348/69 7061918 YP_002329572.1 CDS fliI NC_011601.1 2112997 2114370 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2112997..2114370 Escherichia coli O127:H6 str. E2348/69 7061919 YP_002329573.1 CDS fliJ NC_011601.1 2114389 2114832 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2114389..2114832 Escherichia coli O127:H6 str. E2348/69 7061920 YP_002329574.1 CDS fliK NC_011601.1 2114829 2115956 D flagellar hook-length control protein 2114829..2115956 Escherichia coli O127:H6 str. E2348/69 7061921 YP_002329575.1 CDS fliL NC_011601.1 2116061 2116525 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2116061..2116525 Escherichia coli O127:H6 str. E2348/69 7061922 YP_002329576.1 CDS fliM NC_011601.1 2116530 2117534 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2116530..2117534 Escherichia coli O127:H6 str. E2348/69 7061923 YP_002329577.1 CDS fliN NC_011601.1 2117531 2117944 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2117531..2117944 Escherichia coli O127:H6 str. E2348/69 7061924 YP_002329578.1 CDS fliO NC_011601.1 2117947 2118312 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2117947..2118312 Escherichia coli O127:H6 str. E2348/69 7061925 YP_002329579.1 CDS fliP NC_011601.1 2118312 2119049 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2118312..2119049 Escherichia coli O127:H6 str. E2348/69 7061926 YP_002329580.1 CDS fliQ NC_011601.1 2119059 2119328 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2119059..2119328 Escherichia coli O127:H6 str. E2348/69 7061927 YP_002329581.1 CDS fliR NC_011601.1 2119337 2120122 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2119337..2120122 Escherichia coli O127:H6 str. E2348/69 7061928 YP_002329582.1 CDS rcsA NC_011601.1 2120412 2121035 D DNA-binding transcriptional activator, co-regulator with RcsB 2120412..2121035 Escherichia coli O127:H6 str. E2348/69 7061929 YP_002329583.1 CDS dsrB NC_011601.1 2121079 2121267 R hypothetical protein complement(2121079..2121267) Escherichia coli O127:H6 str. E2348/69 7063963 YP_002329584.1 CDS yodD NC_011601.1 2121430 2121657 D hypothetical protein 2121430..2121657 Escherichia coli O127:H6 str. E2348/69 7065069 YP_002329585.1 CDS yedP NC_011601.1 2121955 2122770 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2121955..2122770 Escherichia coli O127:H6 str. E2348/69 7065068 YP_002329586.1 CDS yodC NC_011601.1 2124631 2124813 R hypothetical protein complement(2124631..2124813) Escherichia coli O127:H6 str. E2348/69 7063053 YP_002329587.1 CDS yedI NC_011601.1 2124892 2125809 R hypothetical protein complement(2124892..2125809) Escherichia coli O127:H6 str. E2348/69 7061218 YP_002329588.1 CDS yedA NC_011601.1 2125982 2126902 D hypothetical protein 2125982..2126902 Escherichia coli O127:H6 str. E2348/69 7063048 YP_002329589.1 CDS vsr NC_011601.1 2126891 2127361 R DNA mismatch endonuclease Vsr of very short patch repair complement(2126891..2127361) Escherichia coli O127:H6 str. E2348/69 7063044 YP_002329590.1 CDS dcm NC_011601.1 2127342 2128760 R DNA cytosine methylase complement(2127342..2128760) Escherichia coli O127:H6 str. E2348/69 7062363 YP_002329591.1 CDS yedJ NC_011601.1 2128827 2129522 R hypothetical protein complement(2128827..2129522) Escherichia coli O127:H6 str. E2348/69 7065227 YP_002329592.1 CDS yedR NC_011601.1 2129562 2129927 R hypothetical protein complement(2129562..2129927) Escherichia coli O127:H6 str. E2348/69 7063049 YP_002329593.1 CDS ysdS NC_011601.1 2130493 2131551 D hypothetical protein 2130493..2131551 Escherichia coli O127:H6 str. E2348/69 7064553 YP_002329594.1 CDS hchA NC_011601.1 2132145 2132996 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2132145..2132996 Escherichia coli O127:H6 str. E2348/69 7063237 YP_002329595.1 CDS yedV NC_011601.1 2133104 2134462 R sensory kinase in two-component regulatory system with YedW complement(2133104..2134462) Escherichia coli O127:H6 str. E2348/69 7064281 YP_002329596.1 CDS yedW NC_011601.1 2134462 2135133 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2134462..2135133) Escherichia coli O127:H6 str. E2348/69 7063055 YP_002329597.1 CDS yedX NC_011601.1 2135266 2135679 D hypothetical protein 2135266..2135679 Escherichia coli O127:H6 str. E2348/69 7063056 YP_002329598.1 CDS yedY NC_011601.1 2135788 2136792 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2135788..2136792 Escherichia coli O127:H6 str. E2348/69 7063057 YP_002329599.1 CDS yedZ NC_011601.1 2136793 2137428 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2136793..2137428 Escherichia coli O127:H6 str. E2348/69 7063058 YP_002329600.1 CDS yodA NC_011601.1 2137685 2138335 D hypothetical protein 2137685..2138335 Escherichia coli O127:H6 str. E2348/69 7063059 YP_002329601.1 CDS mtfA NC_011601.1 2139188 2139985 D hypothetical protein 2139188..2139985 Escherichia coli O127:H6 str. E2348/69 7065243 YP_002329602.1 CDS yeeL NC_011601.1 2141521 2142573 R ADP-heptose: LPS heptosyltransferase complement(2141521..2142573) Escherichia coli O127:H6 str. E2348/69 7063062 YP_002329603.1 CDS shiA NC_011601.1 2142888 2144204 D shikimate transporter 2142888..2144204 Escherichia coli O127:H6 str. E2348/69 7063063 YP_002329604.1 CDS amn NC_011601.1 2144306 2145760 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2144306..2145760 Escherichia coli O127:H6 str. E2348/69 7062716 YP_002329605.1 CDS yeeN NC_011601.1 2146103 2146819 D hypothetical protein 2146103..2146819 Escherichia coli O127:H6 str. E2348/69 7062455 YP_002329606.1 CDS E2348C_2091 NC_011601.1 2147650 2148525 D hypothetical protein 2147650..2148525 Escherichia coli O127:H6 str. E2348/69 7064957 YP_002329607.1 CDS E2348C_2093 NC_011601.1 2148976 2149266 D hypothetical protein 2148976..2149266 Escherichia coli O127:H6 str. E2348/69 7060940 YP_002329608.1 CDS E2348C_2094 NC_011601.1 2149311 2149607 D hypothetical protein 2149311..2149607 Escherichia coli O127:H6 str. E2348/69 7060941 YP_002329609.1 CDS E2348C_2095 NC_011601.1 2149681 2149923 D H-NS-like DNA-binding protein 2149681..2149923 Escherichia coli O127:H6 str. E2348/69 7060942 YP_002329610.1 CDS E2348C_2096 NC_011601.1 2149973 2150215 D hypothetical protein 2149973..2150215 Escherichia coli O127:H6 str. E2348/69 7060943 YP_002329611.1 CDS E2348C_2097 NC_011601.1 2150446 2151123 R hypothetical protein complement(2150446..2151123) Escherichia coli O127:H6 str. E2348/69 7060944 YP_002329612.1 CDS E2348C_2098 NC_011601.1 2151131 2151427 R hypothetical protein complement(2151131..2151427) Escherichia coli O127:H6 str. E2348/69 7060945 YP_002329613.1 CDS E2348C_2099 NC_011601.1 2151455 2152189 R DNA-binding protein complement(2151455..2152189) Escherichia coli O127:H6 str. E2348/69 7060946 YP_002329614.1 CDS E2348C_2100 NC_011601.1 2153875 2154261 D hypothetical protein 2153875..2154261 Escherichia coli O127:H6 str. E2348/69 7060947 YP_002329615.1 CDS E2348C_2101 NC_011601.1 2154506 2155528 D hypothetical protein 2154506..2155528 Escherichia coli O127:H6 str. E2348/69 7060948 YP_002329616.1 CDS E2348C_2102 NC_011601.1 2155613 2155990 R hypothetical protein complement(2155613..2155990) Escherichia coli O127:H6 str. E2348/69 7060949 YP_002329617.1 CDS E2348C_2103 NC_011601.1 2156022 2156495 R hypothetical protein complement(2156022..2156495) Escherichia coli O127:H6 str. E2348/69 7060950 YP_002329618.1 CDS E2348C_2104 NC_011601.1 2156904 2157458 D lipoprotein 2156904..2157458 Escherichia coli O127:H6 str. E2348/69 7060951 YP_002329619.1 CDS E2348C_2105 NC_011601.1 2157558 2158490 R hypothetical protein complement(2157558..2158490) Escherichia coli O127:H6 str. E2348/69 7060952 YP_002329620.1 CDS E2348C_2106 NC_011601.1 2158503 2160023 R hypothetical protein complement(2158503..2160023) Escherichia coli O127:H6 str. E2348/69 7060953 YP_002329621.1 CDS E2348C_2108 NC_011601.1 2162248 2162553 D hypothetical protein 2162248..2162553 Escherichia coli O127:H6 str. E2348/69 7060955 YP_002329622.1 CDS E2348C_2109 NC_011601.1 2162951 2163508 D type IV pilin-like protein 2162951..2163508 Escherichia coli O127:H6 str. E2348/69 7060956 YP_002329623.1 CDS E2348C_2110 NC_011601.1 2163561 2165024 D hypothetical protein 2163561..2165024 Escherichia coli O127:H6 str. E2348/69 7060957 YP_002329624.1 CDS E2348C_2111 NC_011601.1 2165139 2165483 R hypothetical protein complement(2165139..2165483) Escherichia coli O127:H6 str. E2348/69 7060958 YP_002329625.1 CDS E2348C_2112 NC_011601.1 2165495 2166349 R hypothetical protein complement(2165495..2166349) Escherichia coli O127:H6 str. E2348/69 7060959 YP_002329626.1 CDS E2348C_2113 NC_011601.1 2166339 2167244 R hypothetical protein complement(2166339..2167244) Escherichia coli O127:H6 str. E2348/69 7060960 YP_002329627.1 CDS E2348C_2114 NC_011601.1 2167611 2167862 D hypothetical protein 2167611..2167862 Escherichia coli O127:H6 str. E2348/69 7060961 YP_002329628.1 CDS E2348C_2116 NC_011601.1 2168237 2169472 R P4-family integrase complement(2168237..2169472) Escherichia coli O127:H6 str. E2348/69 7060963 YP_002329629.1 CDS E2348C_2117 NC_011601.1 2169716 2170831 D hypothetical protein 2169716..2170831 Escherichia coli O127:H6 str. E2348/69 7060964 YP_002329630.1 CDS E2348C_2118 NC_011601.1 2170831 2171547 D hypothetical protein 2170831..2171547 Escherichia coli O127:H6 str. E2348/69 7060965 YP_002329631.1 CDS E2348C_2119 NC_011601.1 2171614 2172882 R integrase complement(2171614..2172882) Escherichia coli O127:H6 str. E2348/69 7060966 YP_002329632.1 CDS yeeO NC_011601.1 2173238 2174878 R hypothetical protein complement(2173238..2174878) Escherichia coli O127:H6 str. E2348/69 7061418 YP_002329633.1 CDS cbl NC_011601.1 2174999 2175949 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2174999..2175949) Escherichia coli O127:H6 str. E2348/69 7061416 YP_002329634.1 CDS nac NC_011601.1 2176051 2176968 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2176051..2176968) Escherichia coli O127:H6 str. E2348/69 7064326 YP_002329635.1 CDS erfK NC_011601.1 2177426 2178358 R hypothetical protein complement(2177426..2178358) Escherichia coli O127:H6 str. E2348/69 7061417 YP_002329636.1 CDS cobT NC_011601.1 2178423 2179502 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2178423..2179502) Escherichia coli O127:H6 str. E2348/69 7063866 YP_002329637.1 CDS cobS NC_011601.1 2179514 2180257 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2179514..2180257) Escherichia coli O127:H6 str. E2348/69 7062827 YP_002329638.1 CDS cobU NC_011601.1 2180254 2180799 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(2180254..2180799) Escherichia coli O127:H6 str. E2348/69 7062826 YP_002329639.1 CDS E2348C_2127 NC_011601.1 2180933 2181430 R hypothetical protein complement(2180933..2181430) Escherichia coli O127:H6 str. E2348/69 7062828 YP_002329640.1 CDS pocR NC_011601.1 2181855 2182772 R pdu/cob regulatory protein complement(2181855..2182772) Escherichia coli O127:H6 str. E2348/69 7061149 YP_002329641.1 CDS pduF NC_011601.1 2182975 2183784 R propanediol diffusion facilitator complement(2182975..2183784) Escherichia coli O127:H6 str. E2348/69 7060767 YP_002329642.1 CDS pduA NC_011601.1 2184296 2184580 D propanediol utilization protein PduA 2184296..2184580 Escherichia coli O127:H6 str. E2348/69 7062924 YP_002329643.1 CDS pduB NC_011601.1 2184577 2185389 D propanediol utilization protein PduB 2184577..2185389 Escherichia coli O127:H6 str. E2348/69 7062919 YP_002329644.1 CDS pduC NC_011601.1 2185408 2187009 D propanediol dehydratase, large subunit, AdoCbl-dependent 2185408..2187009 Escherichia coli O127:H6 str. E2348/69 7062920 YP_002329645.1 CDS pduD NC_011601.1 2187082 2187750 D propanediol dehydratase, medium subunit, AdoCbl-dependent 2187082..2187750 Escherichia coli O127:H6 str. E2348/69 7062921 YP_002329646.1 CDS pduE NC_011601.1 2187765 2188283 D propanediol dehydratase, small subunit, AdoCbl-dependent 2187765..2188283 Escherichia coli O127:H6 str. E2348/69 7062922 YP_002329647.1 CDS pduG NC_011601.1 2188293 2190125 D propanediol dehydratase reactivation protein PduG 2188293..2190125 Escherichia coli O127:H6 str. E2348/69 7062923 YP_002329648.1 CDS pduH NC_011601.1 2190115 2190465 D propanediol dehydratase reactivation protein PduH 2190115..2190465 Escherichia coli O127:H6 str. E2348/69 7062925 YP_002329649.1 CDS pduJ NC_011601.1 2190485 2190760 D propanediol utilization protein PduJ 2190485..2190760 Escherichia coli O127:H6 str. E2348/69 7062926 YP_002329650.1 CDS pduK NC_011601.1 2190784 2191206 D propanediol utilization protein PduK 2190784..2191206 Escherichia coli O127:H6 str. E2348/69 7062927 YP_002329651.1 CDS pduL NC_011601.1 2191209 2191841 D propanediol utilization protein 2191209..2191841 Escherichia coli O127:H6 str. E2348/69 7062928 YP_002329652.1 CDS pduM NC_011601.1 2191838 2192329 D propanediol utilization protein 2191838..2192329 Escherichia coli O127:H6 str. E2348/69 7062929 YP_002329653.1 CDS pduN NC_011601.1 2192333 2192608 D propanediol utilization protein PduN 2192333..2192608 Escherichia coli O127:H6 str. E2348/69 7062930 YP_002329654.1 CDS pduO NC_011601.1 2192620 2193627 D propanediol utilization protein PduO, AdoCbl-dependent 2192620..2193627 Escherichia coli O127:H6 str. E2348/69 7062931 YP_002329655.1 CDS pduP NC_011601.1 2193624 2195009 D CoA-dependent proprionaldehyde dehydrogenase 2193624..2195009 Escherichia coli O127:H6 str. E2348/69 7062932 YP_002329656.1 CDS pduQ NC_011601.1 2195020 2196132 D propanol dehydrogenase 2195020..2196132 Escherichia coli O127:H6 str. E2348/69 7062933 YP_002329657.1 CDS pduS NC_011601.1 2196129 2197472 D propanediol utilization protein 2196129..2197472 Escherichia coli O127:H6 str. E2348/69 7062934 YP_002329658.1 CDS pduT NC_011601.1 2197475 2198029 D propanediol utilization protein PduT 2197475..2198029 Escherichia coli O127:H6 str. E2348/69 7062935 YP_002329659.1 CDS pduU NC_011601.1 2198029 2198379 D propanediol utilization protein PduU 2198029..2198379 Escherichia coli O127:H6 str. E2348/69 7062936 YP_002329660.1 CDS pduV NC_011601.1 2198384 2198827 D propanediol utilization protein 2198384..2198827 Escherichia coli O127:H6 str. E2348/69 7062937 YP_002329661.1 CDS yeeX NC_011601.1 2198928 2199257 R hypothetical protein complement(2198928..2199257) Escherichia coli O127:H6 str. E2348/69 7062938 YP_002329662.1 CDS yeeA NC_011601.1 2199429 2200487 R hypothetical protein complement(2199429..2200487) Escherichia coli O127:H6 str. E2348/69 7063066 YP_002329663.1 CDS sbmC NC_011601.1 2200727 2201158 R DNA gyrase inhibitor complement(2200727..2201158) Escherichia coli O127:H6 str. E2348/69 7063060 YP_002329664.1 CDS dacD NC_011601.1 2201277 2202443 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2201277..2202443) Escherichia coli O127:H6 str. E2348/69 7065336 YP_002329665.1 CDS sbcB NC_011601.1 2202652 2204079 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2202652..2204079 Escherichia coli O127:H6 str. E2348/69 7065215 YP_002329666.1 CDS yeeF NC_011601.1 2204153 2205511 R amino-acid transporter complement(2204153..2205511) Escherichia coli O127:H6 str. E2348/69 7065332 YP_002329667.1 CDS yeeY NC_011601.1 2205778 2206707 R DNA-binding transcriptional regulator complement(2205778..2206707) Escherichia coli O127:H6 str. E2348/69 7063061 YP_002329668.1 CDS yeeZ NC_011601.1 2206753 2207577 R epimerase complement(2206753..2207577) Escherichia coli O127:H6 str. E2348/69 7063067 YP_002329669.1 CDS yoeB NC_011601.1 2207660 2207914 R toxin of the YoeB-YefM toxin-antitoxin system complement(2207660..2207914) Escherichia coli O127:H6 str. E2348/69 7063068 YP_002329670.1 CDS yefM NC_011601.1 2207911 2208162 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2207911..2208162) Escherichia coli O127:H6 str. E2348/69 7061220 YP_002329672.1 CDS hisG NC_011601.1 2208641 2209540 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2208641..2209540 Escherichia coli O127:H6 str. E2348/69 7062152 YP_002329673.1 CDS hisD NC_011601.1 2209546 2210850 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2209546..2210850 Escherichia coli O127:H6 str. E2348/69 7062148 YP_002329674.1 CDS hisC NC_011601.1 2210847 2211917 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2210847..2211917 Escherichia coli O127:H6 str. E2348/69 7062146 YP_002329675.1 CDS hisB NC_011601.1 2211917 2212984 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2211917..2212984 Escherichia coli O127:H6 str. E2348/69 7062145 YP_002329676.1 CDS hisH NC_011601.1 2212984 2213574 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2212984..2213574 Escherichia coli O127:H6 str. E2348/69 7062144 YP_002329677.1 CDS hisA NC_011601.1 2213574 2214311 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2213574..2214311 Escherichia coli O127:H6 str. E2348/69 7062149 YP_002329678.1 CDS hisF NC_011601.1 2214293 2215069 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2214293..2215069 Escherichia coli O127:H6 str. E2348/69 7062143 YP_002329679.1 CDS hisI NC_011601.1 2215063 2215674 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2215063..2215674 Escherichia coli O127:H6 str. E2348/69 7062147 YP_002329680.1 CDS wzz NC_011601.1 2215860 2216837 R regulator of length of O-antigen component of lipopolysaccharide chains complement(2215860..2216837) Escherichia coli O127:H6 str. E2348/69 7062150 YP_002329681.1 CDS ugd NC_011601.1 2216984 2218150 R UDP-glucose 6-dehydrogenase complement(2216984..2218150) Escherichia coli O127:H6 str. E2348/69 7064854 YP_002329682.1 CDS gnd NC_011601.1 2218399 2219805 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2218399..2219805) Escherichia coli O127:H6 str. E2348/69 7062302 YP_002329683.1 CDS wbiQ NC_011601.1 2219926 2220825 R fucosyltransferase complement(2219926..2220825) Escherichia coli O127:H6 str. E2348/69 7061733 YP_002329684.1 CDS wbiP NC_011601.1 2220833 2221570 R glycosyl transferase family protein complement(2220833..2221570) Escherichia coli O127:H6 str. E2348/69 7062368 YP_002329685.1 CDS wzy NC_011601.1 2221571 2222737 R O-antigen polymerase complement(2221571..2222737) Escherichia coli O127:H6 str. E2348/69 7062367 YP_002329686.1 CDS wbiO NC_011601.1 2222745 2223398 R O-acetyltransferase complement(2222745..2223398) Escherichia coli O127:H6 str. E2348/69 7064852 YP_002329687.1 CDS wzx NC_011601.1 2223395 2224666 R O-antigen flippase complement(2223395..2224666) Escherichia coli O127:H6 str. E2348/69 7062366 YP_002329688.1 CDS manB NC_011601.1 2224679 2226052 R phosphomannomutase complement(2224679..2226052) Escherichia coli O127:H6 str. E2348/69 7064849 YP_002329689.1 CDS manC NC_011601.1 2226056 2227504 R GDP-mannose pyrophosphorylase complement(2226056..2227504) Escherichia coli O127:H6 str. E2348/69 7065284 YP_002329690.1 CDS E2348C_2178 NC_011601.1 2227497 2227997 R GDP-mannose mannosyl hydrolase complement(2227497..2227997) Escherichia coli O127:H6 str. E2348/69 7065285 YP_002329691.1 CDS E2348C_2179 NC_011601.1 2228000 2228965 R bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/GDP-4-dehydro-6-L-deoxygalactose reductase complement(2228000..2228965) Escherichia coli O127:H6 str. E2348/69 7060969 YP_002329692.1 CDS E2348C_2180 NC_011601.1 2228968 2230089 R GDP-D-mannose dehydratase complement(2228968..2230089) Escherichia coli O127:H6 str. E2348/69 7060970 YP_002329693.1 CDS wbiN NC_011601.1 2230116 2231132 R glycosyl transferase family protein complement(2230116..2231132) Escherichia coli O127:H6 str. E2348/69 7060971 YP_002329694.1 CDS galE NC_011601.1 2231151 2232170 R UDP-galactose-4-epimerase complement(2231151..2232170) Escherichia coli O127:H6 str. E2348/69 7062365 YP_002329695.1 CDS galF NC_011601.1 2232480 2233373 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase complement(2232480..2233373) Escherichia coli O127:H6 str. E2348/69 7061616 YP_002329696.1 CDS gne NC_011601.1 2233616 2234611 R UDP-galactose 4-epimerase complement(2233616..2234611) Escherichia coli O127:H6 str. E2348/69 7061617 YP_002329697.1 CDS wcaM NC_011601.1 2234769 2236163 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2234769..2236163) Escherichia coli O127:H6 str. E2348/69 7061734 YP_002329698.1 CDS wcaL NC_011601.1 2236174 2237394 R glycosyl transferase family protein complement(2236174..2237394) Escherichia coli O127:H6 str. E2348/69 7064843 YP_002329699.1 CDS wcaK NC_011601.1 2237391 2238671 R pyruvyl transferase complement(2237391..2238671) Escherichia coli O127:H6 str. E2348/69 7062378 YP_002329700.1 CDS wzxC NC_011601.1 2238743 2240221 R colanic acid exporter complement(2238743..2240221) Escherichia coli O127:H6 str. E2348/69 7062377 YP_002329701.1 CDS wcaJ NC_011601.1 2240223 2241617 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2240223..2241617) Escherichia coli O127:H6 str. E2348/69 7064850 YP_002329702.1 CDS cpsG NC_011601.1 2241672 2243042 R phosphomannomutase complement(2241672..2243042) Escherichia coli O127:H6 str. E2348/69 7062376 YP_002329703.1 CDS cpsB NC_011601.1 2243235 2244671 R mannose-1-phosphate guanylyltransferase complement(2243235..2244671) Escherichia coli O127:H6 str. E2348/69 7062837 YP_002329704.1 CDS wcaI NC_011601.1 2244674 2245897 R glycosyl transferase family protein complement(2244674..2245897) Escherichia coli O127:H6 str. E2348/69 7062836 YP_002329705.1 CDS gmm NC_011601.1 2245894 2246373 R GDP-mannose mannosyl hydrolase complement(2245894..2246373) Escherichia coli O127:H6 str. E2348/69 7062375 YP_002329706.1 CDS fcl NC_011601.1 2246376 2247341 R bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/GDP-4-dehydro-6-L-deoxygalactose reductase complement(2246376..2247341) Escherichia coli O127:H6 str. E2348/69 7061732 YP_002329707.1 CDS gmd NC_011601.1 2247344 2248465 R GDP-D-mannose dehydratase complement(2247344..2248465) Escherichia coli O127:H6 str. E2348/69 7062084 YP_002329708.1 CDS wcaF NC_011601.1 2248492 2249040 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2248492..2249040) Escherichia coli O127:H6 str. E2348/69 7061729 YP_002329709.1 CDS wcaE NC_011601.1 2249056 2249802 R glycosyl transferase family protein complement(2249056..2249802) Escherichia coli O127:H6 str. E2348/69 7062374 YP_002329710.1 CDS wcaD NC_011601.1 2249813 2251030 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2249813..2251030) Escherichia coli O127:H6 str. E2348/69 7062373 YP_002329711.1 CDS wcaC NC_011601.1 2251005 2252222 R glycosyl transferase family protein complement(2251005..2252222) Escherichia coli O127:H6 str. E2348/69 7062372 YP_002329712.1 CDS wcaB NC_011601.1 2252219 2252707 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2252219..2252707) Escherichia coli O127:H6 str. E2348/69 7062371 YP_002329713.1 CDS wcaA NC_011601.1 2252710 2253549 R glycosyl transferase family protein complement(2252710..2253549) Escherichia coli O127:H6 str. E2348/69 7062370 YP_002329714.1 CDS wzc NC_011601.1 2253727 2255889 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2253727..2255889) Escherichia coli O127:H6 str. E2348/69 7062369 YP_002329715.1 CDS wzb NC_011601.1 2255892 2256335 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2255892..2256335) Escherichia coli O127:H6 str. E2348/69 7064848 YP_002329716.1 CDS wza NC_011601.1 2256341 2257480 R lipoprotein required for capsular polysaccharide translocation through the outer membrane complement(2256341..2257480) Escherichia coli O127:H6 str. E2348/69 7064847 YP_002329717.1 CDS yegH NC_011601.1 2258139 2259722 D fused membrane protein/ membrane protein 2258139..2259722 Escherichia coli O127:H6 str. E2348/69 7064846 YP_002329718.1 CDS asmA NC_011601.1 2260171 2262024 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2260171..2262024) Escherichia coli O127:H6 str. E2348/69 7063071 YP_002329719.1 CDS dcd NC_011601.1 2262046 2262627 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2262046..2262627) Escherichia coli O127:H6 str. E2348/69 7061410 YP_002329720.1 CDS udk NC_011601.1 2262719 2263360 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2262719..2263360) Escherichia coli O127:H6 str. E2348/69 7065226 YP_002329721.1 CDS E2348C_2210 NC_011601.1 2264261 2265634 D transposase of ISEc13 2264261..2265634 Escherichia coli O127:H6 str. E2348/69 7061100 YP_002329722.1 CDS alkA NC_011601.1 2268663 2269511 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2268663..2269511) Escherichia coli O127:H6 str. E2348/69 7060972 YP_002329723.1 CDS yegD NC_011601.1 2269645 2270997 D chaperone 2269645..2270997 Escherichia coli O127:H6 str. E2348/69 7062437 YP_002329724.1 CDS yegI NC_011601.1 2271010 2272950 R hypothetical protein complement(2271010..2272950) Escherichia coli O127:H6 str. E2348/69 7063070 YP_002329725.1 CDS yegK NC_011601.1 2272947 2273708 R hypothetical protein complement(2272947..2273708) Escherichia coli O127:H6 str. E2348/69 7063072 YP_002329726.1 CDS yegL NC_011601.1 2273705 2274364 R hypothetical protein complement(2273705..2274364) Escherichia coli O127:H6 str. E2348/69 7063073 YP_002329727.1 CDS E2348C_2216 NC_011601.1 2274837 2276210 D transposase of ISEc13 2274837..2276210 Escherichia coli O127:H6 str. E2348/69 7061101 YP_002329728.1 CDS mdtA NC_011601.1 2276475 2277722 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2276475..2277722 Escherichia coli O127:H6 str. E2348/69 7060973 YP_002329729.1 CDS mdtB NC_011601.1 2277722 2280844 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2277722..2280844 Escherichia coli O127:H6 str. E2348/69 7065306 YP_002329730.1 CDS mdtC NC_011601.1 2280845 2283922 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2280845..2283922 Escherichia coli O127:H6 str. E2348/69 7065307 YP_002329731.1 CDS mdtD NC_011601.1 2283923 2285338 D multidrug efflux system protein MdtE 2283923..2285338 Escherichia coli O127:H6 str. E2348/69 7065308 YP_002329732.1 CDS baeS NC_011601.1 2285335 2286738 D signal transduction histidine-protein kinase BaeS 2285335..2286738 Escherichia coli O127:H6 str. E2348/69 7065309 YP_002329733.1 CDS baeR NC_011601.1 2286735 2287457 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2286735..2287457 Escherichia coli O127:H6 str. E2348/69 7062492 YP_002329734.1 CDS yegP NC_011601.1 2287637 2287969 D hypothetical protein 2287637..2287969 Escherichia coli O127:H6 str. E2348/69 7062491 YP_002329735.1 CDS yegQ NC_011601.1 2288116 2289477 D peptidase 2288116..2289477 Escherichia coli O127:H6 str. E2348/69 7063075 YP_002329736.1 CDS yegR NC_011601.1 2289807 2290124 R hypothetical protein complement(2289807..2290124) Escherichia coli O127:H6 str. E2348/69 7064597 YP_002329737.1 CDS yegS NC_011601.1 2290539 2291438 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2290539..2291438 Escherichia coli O127:H6 str. E2348/69 7063077 YP_002329738.1 CDS E2348C_2227 NC_011601.1 2291519 2292160 R phosphatase complement(2291519..2292160) Escherichia coli O127:H6 str. E2348/69 7063078 YP_002329739.1 CDS atlT NC_011601.1 2292205 2293482 R D-arabitol membrane transporter complement(2292205..2293482) Escherichia coli O127:H6 str. E2348/69 7060974 YP_002329740.1 CDS atlK NC_011601.1 2293551 2295014 R D-xylulose kinase complement(2293551..2295014) Escherichia coli O127:H6 str. E2348/69 7062472 YP_002329741.1 CDS atlD NC_011601.1 2295028 2296395 R D-arabitol dehydrogenase complement(2295028..2296395) Escherichia coli O127:H6 str. E2348/69 7062471 YP_002329742.1 CDS altR NC_011601.1 2296603 2297544 D D-arabitol repressor 2296603..2297544 Escherichia coli O127:H6 str. E2348/69 7062470 YP_002329743.1 CDS gatR NC_011601.1 2299901 2300680 R DNA-binding transcriptional repressor GatR complement(2299901..2300680) Escherichia coli O127:H6 str. E2348/69 7064576 YP_002329744.1 CDS gatD NC_011601.1 2300780 2301820 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2300780..2301820) Escherichia coli O127:H6 str. E2348/69 7061636 YP_002329745.1 CDS gatC NC_011601.1 2301868 2303223 R PTS system galactitol-specific transporter subunit IIC complement(2301868..2303223) Escherichia coli O127:H6 str. E2348/69 7061635 YP_002329746.1 CDS gatB NC_011601.1 2303227 2303511 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2303227..2303511) Escherichia coli O127:H6 str. E2348/69 7061634 YP_002329747.1 CDS gatA NC_011601.1 2303542 2303994 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2303542..2303994) Escherichia coli O127:H6 str. E2348/69 7061633 YP_002329748.1 CDS gatZ NC_011601.1 2304004 2305266 R D-tagatose 1,6-bisphosphate aldolase 2, subunit complement(2304004..2305266) Escherichia coli O127:H6 str. E2348/69 7061632 YP_002329749.1 CDS gatY NC_011601.1 2305295 2306149 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2305295..2306149) Escherichia coli O127:H6 str. E2348/69 7061638 YP_002329750.1 CDS fbaB NC_011601.1 2306376 2307428 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2306376..2307428) Escherichia coli O127:H6 str. E2348/69 7061637 YP_002329751.1 CDS yegT NC_011601.1 2307686 2308963 D nucleoside transporter 2307686..2308963 Escherichia coli O127:H6 str. E2348/69 7062082 YP_002329752.1 CDS yegU NC_011601.1 2308960 2309964 D hydrolase 2308960..2309964 Escherichia coli O127:H6 str. E2348/69 7063079 YP_002329753.1 CDS yegV NC_011601.1 2309961 2310926 D kinase 2309961..2310926 Escherichia coli O127:H6 str. E2348/69 7063080 YP_002329754.1 CDS yegW NC_011601.1 2310900 2311646 R DNA-binding transcriptional regulator complement(2310900..2311646) Escherichia coli O127:H6 str. E2348/69 7063081 YP_002329755.1 CDS yegX NC_011601.1 2311698 2312516 R hydrolase complement(2311698..2312516) Escherichia coli O127:H6 str. E2348/69 7063082 YP_002329756.1 CDS thiD NC_011601.1 2312581 2313381 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2312581..2313381) Escherichia coli O127:H6 str. E2348/69 7063083 YP_002329757.1 CDS thiM NC_011601.1 2313378 2314157 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2313378..2314157) Escherichia coli O127:H6 str. E2348/69 7061781 YP_002329758.1 CDS rcnR NC_011601.1 2314380 2314652 R hypothetical protein complement(2314380..2314652) Escherichia coli O127:H6 str. E2348/69 7061150 YP_002329759.1 CDS rcnA NC_011601.1 2314773 2315603 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2314773..2315603 Escherichia coli O127:H6 str. E2348/69 7063962 YP_002329760.1 CDS yohN NC_011601.1 2315822 2316160 D hypothetical protein 2315822..2316160 Escherichia coli O127:H6 str. E2348/69 7063961 YP_002329761.1 CDS E2348C_2253 NC_011601.1 2316194 2317567 R transposase of ISEc13 complement(2316194..2317567) Escherichia coli O127:H6 str. E2348/69 7061102 YP_002329762.1 CDS yehA NC_011601.1 2317801 2318835 R fimbrial protein-like protein complement(2317801..2318835) Escherichia coli O127:H6 str. E2348/69 7060976 YP_002329763.1 CDS yehB NC_011601.1 2318851 2321331 R outer membrane protein complement(2318851..2321331) Escherichia coli O127:H6 str. E2348/69 7063084 YP_002329764.1 CDS yehD NC_011601.1 2322103 2322645 R fimbrial protein-like protein complement(2322103..2322645) Escherichia coli O127:H6 str. E2348/69 7063086 YP_002329765.1 CDS yehE NC_011601.1 2322939 2323220 R hypothetical protein complement(2322939..2323220) Escherichia coli O127:H6 str. E2348/69 7063087 YP_002329766.1 CDS mrp NC_011601.1 2323483 2324592 R ATPase complement(2323483..2324592) Escherichia coli O127:H6 str. E2348/69 7063088 YP_002329767.1 CDS metG NC_011601.1 2324724 2326757 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2324724..2326757 Escherichia coli O127:H6 str. E2348/69 7060870 YP_002329768.1 CDS yehH NC_011601.1 2326898 2330665 D regulator 2326898..2330665 Escherichia coli O127:H6 str. E2348/69 7063761 YP_002329769.1 CDS yehI NC_011601.1 2330704 2334330 D hypothetical protein 2330704..2334330 Escherichia coli O127:H6 str. E2348/69 7063089 YP_002329771.1 CDS yehL NC_011601.1 2335409 2336497 D transporter subunit: ATP-binding component of ABC superfamily 2335409..2336497 Escherichia coli O127:H6 str. E2348/69 7060977 YP_002329772.1 CDS yehM NC_011601.1 2336508 2338787 D hypothetical protein 2336508..2338787 Escherichia coli O127:H6 str. E2348/69 7063092 YP_002329773.1 CDS yehP NC_011601.1 2338780 2339916 D hypothetical protein 2338780..2339916 Escherichia coli O127:H6 str. E2348/69 7063093 YP_002329774.1 CDS yehQ NC_011601.1 2339913 2341916 D hypothetical protein 2339913..2341916 Escherichia coli O127:H6 str. E2348/69 7063094 YP_002329775.1 CDS yehR NC_011601.1 2342041 2342502 D hypothetical protein 2342041..2342502 Escherichia coli O127:H6 str. E2348/69 7063095 YP_002329776.1 CDS yehS NC_011601.1 2342543 2343013 R hypothetical protein complement(2342543..2343013) Escherichia coli O127:H6 str. E2348/69 7063096 YP_002329777.1 CDS yehT NC_011601.1 2343060 2343779 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2343060..2343779) Escherichia coli O127:H6 str. E2348/69 7063097 YP_002329778.1 CDS yehU NC_011601.1 2343776 2345461 R sensory kinase in two-component system with YehT complement(2343776..2345461) Escherichia coli O127:H6 str. E2348/69 7063098 YP_002329779.1 CDS mlrA NC_011601.1 2345683 2346414 D DNA-binding transcriptional regulator 2345683..2346414 Escherichia coli O127:H6 str. E2348/69 7063099 YP_002329780.1 CDS yohO NC_011601.1 2346474 2346581 D hypothetical protein 2346474..2346581 Escherichia coli O127:H6 str. E2348/69 7063793 YP_002329781.1 CDS yehW NC_011601.1 2346562 2347293 R transporter subunit: membrane component of ABC superfamily complement(2346562..2347293) Escherichia coli O127:H6 str. E2348/69 7061226 YP_002329782.1 CDS yehX NC_011601.1 2347298 2348224 R transporter subunit: ATP-binding component of ABC superfamily complement(2347298..2348224) Escherichia coli O127:H6 str. E2348/69 7063100 YP_002329783.1 CDS yehY NC_011601.1 2348217 2349374 R transporter subunit: membrane component of ABC superfamily complement(2348217..2349374) Escherichia coli O127:H6 str. E2348/69 7063101 YP_002329784.1 CDS osmF NC_011601.1 2349381 2350298 R transporter subunit: periplasmic-binding component of ABC superfamily complement(2349381..2350298) Escherichia coli O127:H6 str. E2348/69 7063102 YP_002329785.1 CDS bglX NC_011601.1 2350488 2352785 R beta-D-glucoside glucohydrolase, periplasmic complement(2350488..2352785) Escherichia coli O127:H6 str. E2348/69 7062892 YP_002329786.1 CDS dld NC_011601.1 2352981 2354696 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2352981..2354696 Escherichia coli O127:H6 str. E2348/69 7062518 YP_002329787.1 CDS pbpG NC_011601.1 2354735 2355667 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2354735..2355667) Escherichia coli O127:H6 str. E2348/69 7065039 YP_002329788.1 CDS yohC NC_011601.1 2355841 2356428 R hypothetical protein complement(2355841..2356428) Escherichia coli O127:H6 str. E2348/69 7062914 YP_002329789.1 CDS yohD NC_011601.1 2356598 2357176 D hypothetical protein 2356598..2357176 Escherichia coli O127:H6 str. E2348/69 7061221 YP_002329790.1 CDS yohF NC_011601.1 2357296 2358057 R acetoin dehydrogenase complement(2357296..2358057) Escherichia coli O127:H6 str. E2348/69 7061222 YP_002329791.1 CDS mdtQ NC_011601.1 2358110 2359546 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2358110..2359546) Escherichia coli O127:H6 str. E2348/69 7061223 YP_002329792.1 CDS dusC NC_011601.1 2360241 2361191 R tRNA-dihydrouridine synthase C complement(2360241..2361191) Escherichia coli O127:H6 str. E2348/69 7065321 YP_002329793.1 CDS yohJ NC_011601.1 2361430 2361828 D hypothetical protein 2361430..2361828 Escherichia coli O127:H6 str. E2348/69 7065073 YP_002329794.1 CDS yohK NC_011601.1 2361825 2362520 D hypothetical protein 2361825..2362520 Escherichia coli O127:H6 str. E2348/69 7061224 YP_002329795.1 CDS cdd NC_011601.1 2362650 2363534 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2362650..2363534 Escherichia coli O127:H6 str. E2348/69 7061225 YP_002329796.1 CDS sanA NC_011601.1 2363684 2364403 D hypothetical protein 2363684..2364403 Escherichia coli O127:H6 str. E2348/69 7064341 YP_002329797.1 CDS yeiS NC_011601.1 2364406 2364645 D hypothetical protein 2364406..2364645 Escherichia coli O127:H6 str. E2348/69 7065326 YP_002329798.1 CDS yeiT NC_011601.1 2364839 2366077 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2364839..2366077 Escherichia coli O127:H6 str. E2348/69 7063116 YP_002329799.1 CDS yeiA NC_011601.1 2366071 2367306 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2366071..2367306 Escherichia coli O127:H6 str. E2348/69 7063117 YP_002329800.1 CDS mglC NC_011601.1 2367549 2368559 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2367549..2368559) Escherichia coli O127:H6 str. E2348/69 7063103 YP_002329801.1 CDS mglA NC_011601.1 2368575 2370095 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2368575..2370095) Escherichia coli O127:H6 str. E2348/69 7063779 YP_002329802.1 CDS mglB NC_011601.1 2370156 2371154 R methyl-galactoside transporter subunit complement(2370156..2371154) Escherichia coli O127:H6 str. E2348/69 7063777 YP_002329803.1 CDS galS NC_011601.1 2371434 2372474 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2371434..2372474) Escherichia coli O127:H6 str. E2348/69 7063778 YP_002329804.1 CDS yeiB NC_011601.1 2372616 2373773 R hypothetical protein complement(2372616..2373773) Escherichia coli O127:H6 str. E2348/69 7061622 YP_002329805.1 CDS folE NC_011601.1 2373790 2374458 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2373790..2374458) Escherichia coli O127:H6 str. E2348/69 7063104 YP_002329806.1 CDS yeiG NC_011601.1 2374716 2375552 D esterase 2374716..2375552 Escherichia coli O127:H6 str. E2348/69 7061942 YP_002329807.1 CDS cirA NC_011601.1 2375584 2377575 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2375584..2377575) Escherichia coli O127:H6 str. E2348/69 7063107 YP_002329808.1 CDS lysP NC_011601.1 2377867 2379336 R lysine transporter complement(2377867..2379336) Escherichia coli O127:H6 str. E2348/69 7062796 YP_002329809.1 CDS yeiE NC_011601.1 2379541 2380422 R DNA-binding transcriptional regulator complement(2379541..2380422) Escherichia coli O127:H6 str. E2348/69 7065252 YP_002329810.1 CDS yeiH NC_011601.1 2380521 2381570 D hypothetical protein 2380521..2381570 Escherichia coli O127:H6 str. E2348/69 7063106 YP_002329811.1 CDS nfo NC_011601.1 2381644 2382501 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2381644..2382501 Escherichia coli O127:H6 str. E2348/69 7063108 YP_002329812.1 CDS yeiI NC_011601.1 2382505 2383593 D hypothetical protein 2382505..2383593 Escherichia coli O127:H6 str. E2348/69 7065382 YP_002329813.1 CDS nupX NC_011601.1 2383649 2384899 R nucleoside transporter complement(2383649..2384899) Escherichia coli O127:H6 str. E2348/69 7063109 YP_002329814.1 CDS rihB NC_011601.1 2384999 2385940 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2384999..2385940) Escherichia coli O127:H6 str. E2348/69 7062867 YP_002329815.1 CDS yeiL NC_011601.1 2386109 2386768 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2386109..2386768 Escherichia coli O127:H6 str. E2348/69 7060825 YP_002329816.1 CDS yeiM NC_011601.1 2386835 2388085 R nucleoside transporter complement(2386835..2388085) Escherichia coli O127:H6 str. E2348/69 7063110 YP_002329817.1 CDS yeiN NC_011601.1 2388179 2389117 R hypothetical protein complement(2388179..2389117) Escherichia coli O127:H6 str. E2348/69 7063111 YP_002329818.1 CDS yeiC NC_011601.1 2389105 2390046 R hypothetical protein complement(2389105..2390046) Escherichia coli O127:H6 str. E2348/69 7063112 YP_002329819.1 CDS fruA NC_011601.1 2390502 2392193 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2390502..2392193) Escherichia coli O127:H6 str. E2348/69 7063105 YP_002329820.1 CDS fruK NC_011601.1 2392210 2393148 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2392210..2393148) Escherichia coli O127:H6 str. E2348/69 7061959 YP_002329821.1 CDS fruB NC_011601.1 2393148 2394278 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2393148..2394278) Escherichia coli O127:H6 str. E2348/69 7061961 YP_002329822.1 CDS setB NC_011601.1 2394645 2395826 D lactose/glucose efflux system 2394645..2395826 Escherichia coli O127:H6 str. E2348/69 7061960 YP_002329823.1 CDS yeiW NC_011601.1 2395823 2396077 R hypothetical protein complement(2395823..2396077) Escherichia coli O127:H6 str. E2348/69 7062708 YP_002329824.1 CDS yeiP NC_011601.1 2396232 2396804 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2396232..2396804 Escherichia coli O127:H6 str. E2348/69 7063119 YP_002329825.1 CDS yeiQ NC_011601.1 2397027 2398493 D dehydrogenase, NAD-dependent 2397027..2398493 Escherichia coli O127:H6 str. E2348/69 7063113 YP_002329826.1 CDS yeiR NC_011601.1 2398611 2399597 D hypothetical protein 2398611..2399597 Escherichia coli O127:H6 str. E2348/69 7063114 YP_002329827.1 CDS yeiU NC_011601.1 2399636 2400349 D undecaprenyl pyrophosphate phosphatase 2399636..2400349 Escherichia coli O127:H6 str. E2348/69 7063115 YP_002329828.1 CDS spr NC_011601.1 2400761 2401327 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2400761..2401327 Escherichia coli O127:H6 str. E2348/69 7063118 YP_002329829.1 CDS rtn NC_011601.1 2401508 2403064 D hypothetical protein 2401508..2403064 Escherichia coli O127:H6 str. E2348/69 7062751 YP_002329830.1 CDS yejA NC_011601.1 2403146 2404960 D oligopeptide transporter subunit 2403146..2404960 Escherichia coli O127:H6 str. E2348/69 7064577 YP_002329831.1 CDS yejB NC_011601.1 2404961 2406055 D oligopeptide transporter subunit 2404961..2406055 Escherichia coli O127:H6 str. E2348/69 7063120 YP_002329832.1 CDS yejE NC_011601.1 2406055 2407080 D oligopeptide transporter subunit 2406055..2407080 Escherichia coli O127:H6 str. E2348/69 7063121 YP_002329833.1 CDS yejF NC_011601.1 2407082 2408671 D fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding components 2407082..2408671 Escherichia coli O127:H6 str. E2348/69 7063122 YP_002329834.1 CDS yejG NC_011601.1 2408675 2409019 R hypothetical protein complement(2408675..2409019) Escherichia coli O127:H6 str. E2348/69 7063123 YP_002329835.1 CDS bcr NC_011601.1 2409353 2410543 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2409353..2410543) Escherichia coli O127:H6 str. E2348/69 7063124 YP_002329836.1 CDS rsuA NC_011601.1 2410571 2411266 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2410571..2411266) Escherichia coli O127:H6 str. E2348/69 7062498 YP_002329837.1 CDS yejH NC_011601.1 2411416 2413176 D ATP-dependet helicase 2411416..2413176 Escherichia coli O127:H6 str. E2348/69 7064566 YP_002329838.1 CDS rplY NC_011601.1 2413301 2413585 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2413301..2413585 Escherichia coli O127:H6 str. E2348/69 7063125 YP_002329839.1 CDS yejK NC_011601.1 2413724 2414731 R nucleoid-associated protein NdpA complement(2413724..2414731) Escherichia coli O127:H6 str. E2348/69 7061852 YP_002329840.1 CDS yejL NC_011601.1 2414913 2415140 D hypothetical protein 2414913..2415140 Escherichia coli O127:H6 str. E2348/69 7063126 YP_002329841.1 CDS yejM NC_011601.1 2415160 2416920 D hydrolase, inner membrane 2415160..2416920 Escherichia coli O127:H6 str. E2348/69 7063127 YP_002329842.1 CDS narP NC_011601.1 2418446 2419093 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2418446..2419093 Escherichia coli O127:H6 str. E2348/69 7063129 YP_002329843.1 CDS ccmH NC_011601.1 2419128 2420180 R heme lyase, CcmH subunit complement(2419128..2420180) Escherichia coli O127:H6 str. E2348/69 7060937 YP_002329844.1 CDS ccmG NC_011601.1 2420177 2420734 R periplasmic thioredoxin CcmG of cytochrome c-type biogenesis complement(2420177..2420734) Escherichia coli O127:H6 str. E2348/69 7064339 YP_002329845.1 CDS ccmF NC_011601.1 2420731 2422674 R heme lyase, CcmF subunit complement(2420731..2422674) Escherichia coli O127:H6 str. E2348/69 7064338 YP_002329846.1 CDS ccmE NC_011601.1 2422671 2423150 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2422671..2423150) Escherichia coli O127:H6 str. E2348/69 7064337 YP_002329847.1 CDS ccmD NC_011601.1 2423147 2423356 R cytochrome c biogenesis protein CcmD complement(2423147..2423356) Escherichia coli O127:H6 str. E2348/69 7064336 YP_002329848.1 CDS ccmC NC_011601.1 2423353 2424090 R heme exporter protein C; membrane component of ABC superfamily complement(2423353..2424090) Escherichia coli O127:H6 str. E2348/69 7064335 YP_002329849.1 CDS ccmB NC_011601.1 2424132 2424794 R heme exporter subunit complement(2424132..2424794) Escherichia coli O127:H6 str. E2348/69 7064334 YP_002329850.1 CDS ccmA NC_011601.1 2424791 2425408 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2424791..2425408) Escherichia coli O127:H6 str. E2348/69 7064333 YP_002329851.1 CDS napC NC_011601.1 2425427 2426029 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2425427..2426029) Escherichia coli O127:H6 str. E2348/69 7064332 YP_002329852.1 CDS napB NC_011601.1 2426039 2426488 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2426039..2426488) Escherichia coli O127:H6 str. E2348/69 7060926 YP_002329853.1 CDS napH NC_011601.1 2426485 2427348 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2426485..2427348) Escherichia coli O127:H6 str. E2348/69 7060925 YP_002329854.1 CDS napG NC_011601.1 2427335 2428030 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2427335..2428030) Escherichia coli O127:H6 str. E2348/69 7060930 YP_002329855.1 CDS napA NC_011601.1 2428037 2430523 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2428037..2430523) Escherichia coli O127:H6 str. E2348/69 7060929 YP_002329856.1 CDS napD NC_011601.1 2430520 2430783 R assembly protein for periplasmic nitrate reductase complement(2430520..2430783) Escherichia coli O127:H6 str. E2348/69 7060924 YP_002329857.1 CDS napF NC_011601.1 2430773 2431267 R role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein complement(2430773..2431267) Escherichia coli O127:H6 str. E2348/69 7060927 YP_002329858.1 CDS yojO NC_011601.1 2431376 2431540 D hypothetical protein 2431376..2431540 Escherichia coli O127:H6 str. E2348/69 7060928 YP_002329859.1 CDS eco NC_011601.1 2431675 2432163 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2431675..2432163 Escherichia coli O127:H6 str. E2348/69 7061228 YP_002329860.1 CDS mqo NC_011601.1 2432313 2433959 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2432313..2433959) Escherichia coli O127:H6 str. E2348/69 7063829 YP_002329861.1 CDS yojI NC_011601.1 2434177 2435820 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component complement(2434177..2435820) Escherichia coli O127:H6 str. E2348/69 7063828 YP_002329862.1 CDS alkB NC_011601.1 2435896 2436546 R oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions complement(2435896..2436546) Escherichia coli O127:H6 str. E2348/69 7061227 YP_002329863.1 CDS ada NC_011601.1 2436546 2437610 R fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase complement(2436546..2437610) Escherichia coli O127:H6 str. E2348/69 7062438 YP_002329864.1 CDS apbE NC_011601.1 2437684 2438739 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2437684..2438739) Escherichia coli O127:H6 str. E2348/69 7062404 YP_002329865.1 CDS ompC NC_011601.1 2438851 2439966 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2438851..2439966) Escherichia coli O127:H6 str. E2348/69 7061349 YP_002329866.1 CDS rcsD NC_011601.1 2440705 2443377 D phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2440705..2443377 Escherichia coli O127:H6 str. E2348/69 7063787 YP_002329867.1 CDS rcsB NC_011601.1 2443394 2444044 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2443394..2444044 Escherichia coli O127:H6 str. E2348/69 7063966 YP_002329868.1 CDS rcsC NC_011601.1 2444244 2447045 R hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2444244..2447045) Escherichia coli O127:H6 str. E2348/69 7063964 YP_002329869.1 CDS atoS NC_011601.1 2447260 2449086 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2447260..2449086 Escherichia coli O127:H6 str. E2348/69 7063965 YP_002329870.1 CDS atoC NC_011601.1 2449083 2450468 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2449083..2450468 Escherichia coli O127:H6 str. E2348/69 7062478 YP_002329871.1 CDS atoD NC_011601.1 2450664 2451326 D acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2450664..2451326 Escherichia coli O127:H6 str. E2348/69 7062475 YP_002329872.1 CDS atoA NC_011601.1 2451326 2451976 D acetyl-CoA: acetoacetyl-CoA transferase, beta subunit 2451326..2451976 Escherichia coli O127:H6 str. E2348/69 7062476 YP_002329873.1 CDS atoE NC_011601.1 2451973 2453295 D short chain fatty acid transporter 2451973..2453295 Escherichia coli O127:H6 str. E2348/69 7062473 YP_002329874.1 CDS atoB NC_011601.1 2453326 2454510 D acetyl-CoA acetyltransferase 2453326..2454510 Escherichia coli O127:H6 str. E2348/69 7062477 YP_002329875.1 CDS yfaP NC_011601.1 2454584 2455360 R hypothetical protein complement(2454584..2455360) Escherichia coli O127:H6 str. E2348/69 7062474 YP_002329876.1 CDS yfaQ NC_011601.1 2455365 2457014 R hypothetical protein complement(2455365..2457014) Escherichia coli O127:H6 str. E2348/69 7063134 YP_002329877.1 CDS yfaS NC_011601.1 2457015 2461622 R hypothetical protein complement(2457015..2461622) Escherichia coli O127:H6 str. E2348/69 7063135 YP_002329878.1 CDS yfaT NC_011601.1 2461556 2462179 R hypothetical protein complement(2461556..2462179) Escherichia coli O127:H6 str. E2348/69 7063136 YP_002329879.1 CDS gyrA NC_011601.1 2464012 2466639 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2464012..2466639) Escherichia coli O127:H6 str. E2348/69 7063130 YP_002329880.1 CDS ubiG NC_011601.1 2466786 2467508 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2466786..2467508 Escherichia coli O127:H6 str. E2348/69 7064278 YP_002329881.1 CDS yfaL NC_011601.1 2467648 2471406 R adhesin complement(2467648..2471406) Escherichia coli O127:H6 str. E2348/69 7062296 YP_002329882.1 CDS nrdA NC_011601.1 2472088 2474373 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2472088..2474373 Escherichia coli O127:H6 str. E2348/69 7063133 YP_002329883.1 CDS nrdB NC_011601.1 2474563 2475693 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2474563..2475693 Escherichia coli O127:H6 str. E2348/69 7065409 YP_002329884.1 CDS yfaE NC_011601.1 2475693 2475947 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2475693..2475947 Escherichia coli O127:H6 str. E2348/69 7065410 YP_002329885.1 CDS inaA NC_011601.1 2476001 2476651 R hypothetical protein complement(2476001..2476651) Escherichia coli O127:H6 str. E2348/69 7063132 YP_002329886.1 CDS glpQ NC_011601.1 2476854 2477930 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2476854..2477930) Escherichia coli O127:H6 str. E2348/69 7063541 YP_002329887.1 CDS glpT NC_011601.1 2477935 2479293 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2477935..2479293) Escherichia coli O127:H6 str. E2348/69 7061700 YP_002329888.1 CDS glpA NC_011601.1 2479568 2481196 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2479568..2481196 Escherichia coli O127:H6 str. E2348/69 7061702 YP_002329889.1 CDS glpB NC_011601.1 2481186 2482445 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2481186..2482445 Escherichia coli O127:H6 str. E2348/69 7061692 YP_002329890.1 CDS glpC NC_011601.1 2482442 2483632 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2482442..2483632 Escherichia coli O127:H6 str. E2348/69 7061693 YP_002329891.1 CDS yfaD NC_011601.1 2483825 2484772 D hypothetical protein 2483825..2484772 Escherichia coli O127:H6 str. E2348/69 7061694 YP_002329892.1 CDS ypaA NC_011601.1 2484785 2485006 D hypothetical protein 2484785..2485006 Escherichia coli O127:H6 str. E2348/69 7063131 YP_002329893.1 CDS yfaU NC_011601.1 2485047 2485799 R aldolase complement(2485047..2485799) Escherichia coli O127:H6 str. E2348/69 7061229 YP_002329894.1 CDS yfaV NC_011601.1 2485868 2487157 R transporter complement(2485868..2487157) Escherichia coli O127:H6 str. E2348/69 7063138 YP_002329895.1 CDS yfaW NC_011601.1 2487214 2488431 R enolase complement(2487214..2488431) Escherichia coli O127:H6 str. E2348/69 7063139 YP_002329896.1 CDS yfaX NC_011601.1 2488434 2489216 R DNA-binding transcriptional regulator complement(2488434..2489216) Escherichia coli O127:H6 str. E2348/69 7063140 YP_002329897.1 CDS yfaY NC_011601.1 2489436 2490638 R competence damage-inducible protein A complement(2489436..2490638) Escherichia coli O127:H6 str. E2348/69 7063141 YP_002329898.1 CDS yfaZ NC_011601.1 2490738 2491280 R outer membrane porin protein complement(2490738..2491280) Escherichia coli O127:H6 str. E2348/69 7063142 YP_002329899.1 CDS nudI NC_011601.1 2491559 2491984 D NUDIX hydrolase 2491559..2491984 Escherichia coli O127:H6 str. E2348/69 7063143 YP_002329900.1 CDS ais NC_011601.1 2492023 2492625 R hypothetical protein complement(2492023..2492625) Escherichia coli O127:H6 str. E2348/69 7065433 YP_002329901.1 CDS arnB NC_011601.1 2492915 2494072 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2492915..2494072 Escherichia coli O127:H6 str. E2348/69 7062428 YP_002329902.1 CDS arnC NC_011601.1 2494076 2495044 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2494076..2495044 Escherichia coli O127:H6 str. E2348/69 7061386 YP_002329903.1 CDS arnA NC_011601.1 2495044 2497026 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2495044..2497026 Escherichia coli O127:H6 str. E2348/69 7061387 YP_002329904.1 CDS yfbH NC_011601.1 2497023 2497913 D hypothetical protein 2497023..2497913 Escherichia coli O127:H6 str. E2348/69 7061385 YP_002329905.1 CDS arnT NC_011601.1 2497913 2499565 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2497913..2499565 Escherichia coli O127:H6 str. E2348/69 7063145 YP_002329906.1 CDS yfbW NC_011601.1 2499562 2499897 D hypothetical protein 2499562..2499897 Escherichia coli O127:H6 str. E2348/69 7061388 YP_002329907.1 CDS yfbJ NC_011601.1 2499897 2500283 D hypothetical protein 2499897..2500283 Escherichia coli O127:H6 str. E2348/69 7063155 YP_002329908.1 CDS pmrD NC_011601.1 2500277 2500549 R polymyxin resistance protein B complement(2500277..2500549) Escherichia coli O127:H6 str. E2348/69 7063146 YP_002329909.1 CDS menE NC_011601.1 2500654 2502009 R O-succinylbenzoic acid--CoA ligase complement(2500654..2502009) Escherichia coli O127:H6 str. E2348/69 7060760 YP_002329910.1 CDS menC NC_011601.1 2502006 2502968 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2502006..2502968) Escherichia coli O127:H6 str. E2348/69 7063753 YP_002329911.1 CDS menB NC_011601.1 2502968 2503825 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2502968..2503825) Escherichia coli O127:H6 str. E2348/69 7063751 YP_002329912.1 CDS yfbB NC_011601.1 2503840 2504598 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(2503840..2504598) Escherichia coli O127:H6 str. E2348/69 7063750 YP_002329913.1 CDS menD NC_011601.1 2504595 2506265 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2504595..2506265) Escherichia coli O127:H6 str. E2348/69 7063144 YP_002329914.1 CDS menF NC_011601.1 2506354 2507649 R isochorismate synthase 2 complement(2506354..2507649) Escherichia coli O127:H6 str. E2348/69 7063752 YP_002329915.1 CDS elaB NC_011601.1 2507728 2508033 R hypothetical protein complement(2507728..2508033) Escherichia coli O127:H6 str. E2348/69 7063754 YP_002329916.1 CDS elaA NC_011601.1 2508088 2508549 R hypothetical protein complement(2508088..2508549) Escherichia coli O127:H6 str. E2348/69 7063842 YP_002329917.1 CDS rbn NC_011601.1 2508614 2509531 D member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2508614..2509531 Escherichia coli O127:H6 str. E2348/69 7063841 YP_002329918.1 CDS yfbL NC_011601.1 2509887 2510858 D peptidase 2509887..2510858 Escherichia coli O127:H6 str. E2348/69 7063953 YP_002329919.1 CDS yfbM NC_011601.1 2510961 2511464 D hypothetical protein 2510961..2511464 Escherichia coli O127:H6 str. E2348/69 7063147 YP_002329920.1 CDS nuoN NC_011601.1 2511531 2512988 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2511531..2512988) Escherichia coli O127:H6 str. E2348/69 7063148 YP_002329921.1 CDS nuoM NC_011601.1 2512995 2514524 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2512995..2514524) Escherichia coli O127:H6 str. E2348/69 7065449 YP_002329922.1 CDS nuoL NC_011601.1 2514755 2516596 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2514755..2516596) Escherichia coli O127:H6 str. E2348/69 7065448 YP_002329923.1 CDS nuoK NC_011601.1 2516593 2516895 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2516593..2516895) Escherichia coli O127:H6 str. E2348/69 7065447 YP_002329924.1 CDS nuoJ NC_011601.1 2516892 2517446 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2516892..2517446) Escherichia coli O127:H6 str. E2348/69 7065446 YP_002329925.1 CDS nuoI NC_011601.1 2517458 2518000 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2517458..2518000) Escherichia coli O127:H6 str. E2348/69 7065445 YP_002329926.1 CDS nuoH NC_011601.1 2518015 2518992 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2518015..2518992) Escherichia coli O127:H6 str. E2348/69 7065444 YP_002329927.1 CDS nuoG NC_011601.1 2518989 2521715 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2518989..2521715) Escherichia coli O127:H6 str. E2348/69 7065443 YP_002329928.1 CDS nuoF NC_011601.1 2521768 2523105 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2521768..2523105) Escherichia coli O127:H6 str. E2348/69 7065442 YP_002329929.1 CDS nuoE NC_011601.1 2523102 2523602 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2523102..2523602) Escherichia coli O127:H6 str. E2348/69 7065441 YP_002329930.1 CDS nuoC NC_011601.1 2523605 2525407 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2523605..2525407) Escherichia coli O127:H6 str. E2348/69 7065440 YP_002329931.1 CDS nuoB NC_011601.1 2525501 2526163 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2525501..2526163) Escherichia coli O127:H6 str. E2348/69 7065439 YP_002329932.1 CDS nuoA NC_011601.1 2526179 2526622 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2526179..2526622) Escherichia coli O127:H6 str. E2348/69 7065438 YP_002329933.1 CDS lrhA NC_011601.1 2527251 2528180 R DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes complement(2527251..2528180) Escherichia coli O127:H6 str. E2348/69 7065437 YP_002329934.1 CDS yfbQ NC_011601.1 2529100 2530317 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2529100..2530317 Escherichia coli O127:H6 str. E2348/69 7065245 YP_002329935.1 CDS yfbR NC_011601.1 2530401 2531000 D hypothetical protein 2530401..2531000 Escherichia coli O127:H6 str. E2348/69 7063149 YP_002329936.1 CDS yfbS NC_011601.1 2531059 2532891 R transporter complement(2531059..2532891) Escherichia coli O127:H6 str. E2348/69 7063150 YP_002329937.1 CDS yfbT NC_011601.1 2532978 2533628 R phosphatase complement(2532978..2533628) Escherichia coli O127:H6 str. E2348/69 7063151 YP_002329938.1 CDS yfbU NC_011601.1 2533639 2534133 R hypothetical protein complement(2533639..2534133) Escherichia coli O127:H6 str. E2348/69 7063152 YP_002329939.1 CDS yfbV NC_011601.1 2534216 2534671 R hypothetical protein complement(2534216..2534671) Escherichia coli O127:H6 str. E2348/69 7063153 YP_002329940.1 CDS ackA NC_011601.1 2535009 2536211 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2535009..2536211 Escherichia coli O127:H6 str. E2348/69 7063154 YP_002329941.1 CDS pta NC_011601.1 2536286 2538430 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2536286..2538430 Escherichia coli O127:H6 str. E2348/69 7062389 YP_002329942.1 CDS yfcC NC_011601.1 2538620 2540140 D hypothetical protein 2538620..2540140 Escherichia coli O127:H6 str. E2348/69 7061333 YP_002329943.1 CDS yfcD NC_011601.1 2540173 2540715 R NUDIX hydrolase complement(2540173..2540715) Escherichia coli O127:H6 str. E2348/69 7063157 YP_002329944.1 CDS yfcE NC_011601.1 2540773 2541324 R phosphodiesterase complement(2540773..2541324) Escherichia coli O127:H6 str. E2348/69 7063158 YP_002329945.1 CDS yfcF NC_011601.1 2541380 2542024 R hypothetical protein complement(2541380..2542024) Escherichia coli O127:H6 str. E2348/69 7063159 YP_002329946.1 CDS yfcG NC_011601.1 2542160 2542807 D glutathione S-transferase 2542160..2542807 Escherichia coli O127:H6 str. E2348/69 7063160 YP_002329947.1 CDS folX NC_011601.1 2542864 2543226 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2542864..2543226 Escherichia coli O127:H6 str. E2348/69 7063161 YP_002329948.1 CDS yfcH NC_011601.1 2543247 2544140 D hypothetical protein 2543247..2544140 Escherichia coli O127:H6 str. E2348/69 7061946 YP_002329949.1 CDS yfcI NC_011601.1 2544188 2545090 R hypothetical protein complement(2544188..2545090) Escherichia coli O127:H6 str. E2348/69 7063162 YP_002329950.1 CDS hisP NC_011601.1 2545286 2546059 R histidine/lysine/arginine/ornithine transporter subunit complement(2545286..2546059) Escherichia coli O127:H6 str. E2348/69 7063163 YP_002329951.1 CDS hisM NC_011601.1 2546067 2546783 R histidine/lysine/arginine/ornithine transporter subunit complement(2546067..2546783) Escherichia coli O127:H6 str. E2348/69 7062154 YP_002329952.1 CDS hisQ NC_011601.1 2546780 2547466 R histidine/lysine/arginine/ornithine transporter subunit HisQ, membrane component of ABC superfamily complement(2546780..2547466) Escherichia coli O127:H6 str. E2348/69 7062153 YP_002329953.1 CDS hisJ NC_011601.1 2547556 2548338 R histidine/lysine/arginine/ornithine transporter subunit complement(2547556..2548338) Escherichia coli O127:H6 str. E2348/69 7062155 YP_002329954.1 CDS argT NC_011601.1 2548559 2549341 R lysine/arginine/ornithine transporter subunit complement(2548559..2549341) Escherichia coli O127:H6 str. E2348/69 7062151 YP_002329955.1 CDS ubiX NC_011601.1 2549607 2550176 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2549607..2550176) Escherichia coli O127:H6 str. E2348/69 7061378 YP_002329956.1 CDS purF NC_011601.1 2550271 2551788 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2550271..2551788) Escherichia coli O127:H6 str. E2348/69 7062298 YP_002329957.1 CDS cvpA NC_011601.1 2551825 2552313 R membrane protein required for colicin V production; colicin V production protein complement(2551825..2552313) Escherichia coli O127:H6 str. E2348/69 7063916 YP_002329958.1 CDS dedD NC_011601.1 2552643 2553305 R hypothetical protein complement(2552643..2553305) Escherichia coli O127:H6 str. E2348/69 7065177 YP_002329959.1 CDS folC NC_011601.1 2553295 2554563 R bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2553295..2554563) Escherichia coli O127:H6 str. E2348/69 7065241 YP_002329960.1 CDS accD NC_011601.1 2554633 2555547 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2554633..2555547) Escherichia coli O127:H6 str. E2348/69 7061940 YP_002329961.1 CDS dedA NC_011601.1 2555703 2556362 R hypothetical protein complement(2555703..2556362) Escherichia coli O127:H6 str. E2348/69 7062383 YP_002329962.1 CDS truA NC_011601.1 2556445 2557257 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2556445..2557257) Escherichia coli O127:H6 str. E2348/69 7065240 YP_002329963.1 CDS usg NC_011601.1 2557257 2558270 R semialdehyde dehydrogenase complement(2557257..2558270) Escherichia coli O127:H6 str. E2348/69 7062263 YP_002329964.1 CDS pdxB NC_011601.1 2558336 2559472 R erythronate-4-phosphate dehydrogenase complement(2558336..2559472) Escherichia coli O127:H6 str. E2348/69 7062330 YP_002329965.1 CDS flk NC_011601.1 2559571 2560566 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2559571..2560566 Escherichia coli O127:H6 str. E2348/69 7062940 YP_002329966.1 CDS yfcJ NC_011601.1 2560563 2561741 R hypothetical protein complement(2560563..2561741) Escherichia coli O127:H6 str. E2348/69 7061934 YP_002329967.1 CDS fabB NC_011601.1 2562006 2563226 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2562006..2563226) Escherichia coli O127:H6 str. E2348/69 7063164 YP_002329968.1 CDS mnmC NC_011601.1 2563385 2565391 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2563385..2565391 Escherichia coli O127:H6 str. E2348/69 7062063 YP_002329969.1 CDS yfcL NC_011601.1 2565512 2565790 R hypothetical protein complement(2565512..2565790) Escherichia coli O127:H6 str. E2348/69 7063800 YP_002329970.1 CDS yfcM NC_011601.1 2565824 2566372 R hypothetical protein complement(2565824..2566372) Escherichia coli O127:H6 str. E2348/69 7063165 YP_002329971.1 CDS yfcA NC_011601.1 2566372 2567181 R hypothetical protein complement(2566372..2567181) Escherichia coli O127:H6 str. E2348/69 7063166 YP_002329972.1 CDS mepA NC_011601.1 2567181 2568005 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2567181..2568005) Escherichia coli O127:H6 str. E2348/69 7063156 YP_002329973.1 CDS aroC NC_011601.1 2568009 2569094 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2568009..2569094) Escherichia coli O127:H6 str. E2348/69 7063755 YP_002329974.1 CDS prmB NC_011601.1 2569129 2570061 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2569129..2570061) Escherichia coli O127:H6 str. E2348/69 7061391 YP_002329975.1 CDS yfcN NC_011601.1 2570227 2570778 D hypothetical protein 2570227..2570778 Escherichia coli O127:H6 str. E2348/69 7061294 YP_002329976.1 CDS yfcO NC_011601.1 2570848 2571711 R hypothetical protein complement(2570848..2571711) Escherichia coli O127:H6 str. E2348/69 7063167 YP_002329977.1 CDS yfcP NC_011601.1 2571713 2572258 R fimbrial subunit protein complement(2571713..2572258) Escherichia coli O127:H6 str. E2348/69 7063168 YP_002329978.1 CDS yfcQ NC_011601.1 2572255 2572734 R fimbrial subunit protein complement(2572255..2572734) Escherichia coli O127:H6 str. E2348/69 7063169 YP_002329979.1 CDS yfcR NC_011601.1 2572731 2573222 R fimbrial protein complement(2572731..2573222) Escherichia coli O127:H6 str. E2348/69 7063170 YP_002329980.1 CDS yfcS NC_011601.1 2573238 2573987 R chaperone complement(2573238..2573987) Escherichia coli O127:H6 str. E2348/69 7063171 YP_002329981.1 CDS yfcU NC_011601.1 2574007 2576646 R outer membrane usher protein complement(2574007..2576646) Escherichia coli O127:H6 str. E2348/69 7063172 YP_002329982.1 CDS yfcV NC_011601.1 2576730 2577296 R fimbrial-protein like protein complement(2576730..2577296) Escherichia coli O127:H6 str. E2348/69 7063173 YP_002329983.1 CDS sixA NC_011601.1 2577959 2578444 R phosphohistidine phosphatase complement(2577959..2578444) Escherichia coli O127:H6 str. E2348/69 7063174 YP_002329984.1 CDS fadJ NC_011601.1 2578647 2580791 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2578647..2580791) Escherichia coli O127:H6 str. E2348/69 7062718 YP_002329985.1 CDS fadI NC_011601.1 2580791 2582101 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2580791..2582101) Escherichia coli O127:H6 str. E2348/69 7062077 YP_002329986.1 CDS yfcZ NC_011601.1 2582327 2582611 R hypothetical protein complement(2582327..2582611) Escherichia coli O127:H6 str. E2348/69 7062076 YP_002329987.1 CDS fadL NC_011601.1 2582983 2584323 D long-chain fatty acid outer membrane transporter 2582983..2584323 Escherichia coli O127:H6 str. E2348/69 7063175 YP_002329988.1 CDS vacJ NC_011601.1 2584385 2585140 R lipoprotein complement(2584385..2585140) Escherichia coli O127:H6 str. E2348/69 7062079 YP_002329989.1 CDS yfdC NC_011601.1 2585434 2586366 D hypothetical protein 2585434..2586366 Escherichia coli O127:H6 str. E2348/69 7062351 YP_002329990.1 CDS E2348C_2486 NC_011601.1 2586642 2587835 D integrase 2586642..2587835 Escherichia coli O127:H6 str. E2348/69 7061172 YP_002329991.1 CDS E2348C_2487 NC_011601.1 2588257 2588625 R tail fiber assembly protein complement(2588257..2588625) Escherichia coli O127:H6 str. E2348/69 7060978 YP_002329992.1 CDS E2348C_2488 NC_011601.1 2588622 2589650 R tail fiber protein complement(2588622..2589650) Escherichia coli O127:H6 str. E2348/69 7060979 YP_002329993.1 CDS E2348C_2489 NC_011601.1 2589650 2590330 R hypothetical protein complement(2589650..2590330) Escherichia coli O127:H6 str. E2348/69 7060980 YP_002329994.1 CDS E2348C_2490 NC_011601.1 2590327 2591526 R hypothetical protein complement(2590327..2591526) Escherichia coli O127:H6 str. E2348/69 7060981 YP_002329995.1 CDS E2348C_2491 NC_011601.1 2591526 2591879 R hypothetical protein complement(2591526..2591879) Escherichia coli O127:H6 str. E2348/69 7060982 YP_002329996.1 CDS E2348C_2492 NC_011601.1 2591879 2592631 R baseplate assembly protein complement(2591879..2592631) Escherichia coli O127:H6 str. E2348/69 7060983 YP_002329997.1 CDS E2348C_2493 NC_011601.1 2592696 2593091 R hypothetical protein complement(2592696..2593091) Escherichia coli O127:H6 str. E2348/69 7060984 YP_002329998.1 CDS E2348C_2494 NC_011601.1 2593078 2593848 R hypothetical protein complement(2593078..2593848) Escherichia coli O127:H6 str. E2348/69 7060985 YP_002329999.1 CDS E2348C_2495 NC_011601.1 2593969 2594310 R hypothetical protein complement(2593969..2594310) Escherichia coli O127:H6 str. E2348/69 7060986 YP_002330000.1 CDS E2348C_2496 NC_011601.1 2594313 2595374 R hypothetical protein complement(2594313..2595374) Escherichia coli O127:H6 str. E2348/69 7060987 YP_002330001.1 CDS E2348C_2497 NC_011601.1 2595377 2595679 R hypothetical protein complement(2595377..2595679) Escherichia coli O127:H6 str. E2348/69 7060988 YP_002330002.1 CDS E2348C_2498 NC_011601.1 2595679 2596266 R hypothetical protein complement(2595679..2596266) Escherichia coli O127:H6 str. E2348/69 7060989 YP_002330003.1 CDS E2348C_2499 NC_011601.1 2596266 2598254 R hypothetical protein complement(2596266..2598254) Escherichia coli O127:H6 str. E2348/69 7060990 YP_002330004.1 CDS E2348C_2500 NC_011601.1 2598432 2598884 R hypothetical protein complement(2598432..2598884) Escherichia coli O127:H6 str. E2348/69 7060991 YP_002330005.1 CDS E2348C_2501 NC_011601.1 2598888 2599328 R hypothetical protein complement(2598888..2599328) Escherichia coli O127:H6 str. E2348/69 7060992 YP_002330006.1 CDS E2348C_2502 NC_011601.1 2599340 2600485 R hypothetical protein complement(2599340..2600485) Escherichia coli O127:H6 str. E2348/69 7060993 YP_002330007.1 CDS E2348C_2503 NC_011601.1 2600489 2601037 R hypothetical protein complement(2600489..2601037) Escherichia coli O127:H6 str. E2348/69 7060994 YP_002330008.1 CDS E2348C_2504 NC_011601.1 2601027 2601416 R hypothetical protein complement(2601027..2601416) Escherichia coli O127:H6 str. E2348/69 7060995 YP_002330009.1 CDS E2348C_2505 NC_011601.1 2601403 2601957 R hypothetical protein complement(2601403..2601957) Escherichia coli O127:H6 str. E2348/69 7060996 YP_002330010.1 CDS E2348C_2506 NC_011601.1 2601954 2602361 R hypothetical protein complement(2601954..2602361) Escherichia coli O127:H6 str. E2348/69 7060997 YP_002330011.1 CDS E2348C_2507 NC_011601.1 2602327 2602548 R hypothetical protein complement(2602327..2602548) Escherichia coli O127:H6 str. E2348/69 7060998 YP_002330012.1 CDS E2348C_2508 NC_011601.1 2602590 2603531 R hypothetical protein complement(2602590..2603531) Escherichia coli O127:H6 str. E2348/69 7060999 YP_002330013.1 CDS E2348C_2509 NC_011601.1 2603543 2604049 R hypothetical protein complement(2603543..2604049) Escherichia coli O127:H6 str. E2348/69 7061000 YP_002330014.1 CDS E2348C_2510 NC_011601.1 2604053 2605273 R hypothetical protein complement(2604053..2605273) Escherichia coli O127:H6 str. E2348/69 7061001 YP_002330015.1 CDS E2348C_2511 NC_011601.1 2605288 2605896 R head morphogenesis protein complement(2605288..2605896) Escherichia coli O127:H6 str. E2348/69 7061002 YP_002330016.1 CDS E2348C_2512 NC_011601.1 2605934 2607379 R portal protein complement(2605934..2607379) Escherichia coli O127:H6 str. E2348/69 7061003 YP_002330017.1 CDS E2348C_2513 NC_011601.1 2607379 2609001 R terminase large subunit complement(2607379..2609001) Escherichia coli O127:H6 str. E2348/69 7061004 YP_002330018.1 CDS E2348C_2514 NC_011601.1 2609004 2609555 R terminase, small subunit complement(2609004..2609555) Escherichia coli O127:H6 str. E2348/69 7061005 YP_002330019.1 CDS E2348C_2515 NC_011601.1 2610256 2610468 R hypothetical protein complement(2610256..2610468) Escherichia coli O127:H6 str. E2348/69 7061006 YP_002330020.1 CDS E2348C_2516 NC_011601.1 2610585 2610977 R hypothetical protein complement(2610585..2610977) Escherichia coli O127:H6 str. E2348/69 7061007 YP_002330021.1 CDS E2348C_2517 NC_011601.1 2610961 2611437 R endolysin complement(2610961..2611437) Escherichia coli O127:H6 str. E2348/69 7061008 YP_002330022.1 CDS E2348C_2518 NC_011601.1 2611421 2611744 R holin protein complement(2611421..2611744) Escherichia coli O127:H6 str. E2348/69 7061009 YP_002330023.1 CDS E2348C_2519 NC_011601.1 2612197 2612709 R HNH endonuclease complement(2612197..2612709) Escherichia coli O127:H6 str. E2348/69 7062252 YP_002330024.1 CDS E2348C_2520 NC_011601.1 2612904 2613422 R late gene regulator complement(2612904..2613422) Escherichia coli O127:H6 str. E2348/69 7061011 YP_002330025.1 CDS E2348C_2521 NC_011601.1 2613604 2613966 R crossover junction endodeoxyribonuclease complement(2613604..2613966) Escherichia coli O127:H6 str. E2348/69 7061012 YP_002330026.1 CDS E2348C_2522 NC_011601.1 2613963 2614253 R hypothetical protein complement(2613963..2614253) Escherichia coli O127:H6 str. E2348/69 7061013 YP_002330027.1 CDS E2348C_2523 NC_011601.1 2614253 2614522 R hypothetical protein complement(2614253..2614522) Escherichia coli O127:H6 str. E2348/69 7061014 YP_002330028.1 CDS E2348C_2524 NC_011601.1 2614515 2614691 R protein NinF complement(2614515..2614691) Escherichia coli O127:H6 str. E2348/69 7061015 YP_002330029.1 CDS E2348C_2525 NC_011601.1 2614691 2615050 R NinX complement(2614691..2615050) Escherichia coli O127:H6 str. E2348/69 7061016 YP_002330030.1 CDS E2348C_2526 NC_011601.1 2615053 2615229 R protein NinE complement(2615053..2615229) Escherichia coli O127:H6 str. E2348/69 7061017 YP_002330031.1 CDS E2348C_2527 NC_011601.1 2615226 2615753 R DNA methylase complement(2615226..2615753) Escherichia coli O127:H6 str. E2348/69 7061018 YP_002330032.1 CDS E2348C_2528 NC_011601.1 2615750 2616190 R protein NinB complement(2615750..2616190) Escherichia coli O127:H6 str. E2348/69 7065452 YP_002330033.1 CDS E2348C_2529 NC_011601.1 2616264 2617640 R replicative DNA helicase complement(2616264..2617640) Escherichia coli O127:H6 str. E2348/69 7065532 YP_002330034.1 CDS E2348C_2530 NC_011601.1 2617637 2618584 R replication protein complement(2617637..2618584) Escherichia coli O127:H6 str. E2348/69 7065533 YP_002330035.1 CDS E2348C_2531 NC_011601.1 2618587 2618859 R hypothetical protein complement(2618587..2618859) Escherichia coli O127:H6 str. E2348/69 7065534 YP_002330036.1 CDS E2348C_2532 NC_011601.1 2618882 2619178 R regulatory protein complement(2618882..2619178) Escherichia coli O127:H6 str. E2348/69 7065535 YP_002330037.1 CDS E2348C_2533 NC_011601.1 2619317 2619517 R antirepressor protein complement(2619317..2619517) Escherichia coli O127:H6 str. E2348/69 7065536 YP_002330038.1 CDS E2348C_2534 NC_011601.1 2619618 2620331 D repressor protein 2619618..2620331 Escherichia coli O127:H6 str. E2348/69 7065537 YP_002330039.1 CDS E2348C_2535 NC_011601.1 2620339 2620776 D hypothetical protein 2620339..2620776 Escherichia coli O127:H6 str. E2348/69 7065538 YP_002330040.1 CDS E2348C_2536 NC_011601.1 2620763 2621134 D hypothetical protein 2620763..2621134 Escherichia coli O127:H6 str. E2348/69 7065539 YP_002330041.1 CDS E2348C_2537 NC_011601.1 2621636 2622019 D early gene regulator 2621636..2622019 Escherichia coli O127:H6 str. E2348/69 7065540 YP_002330042.1 CDS E2348C_2538 NC_011601.1 2622078 2622548 D hypothetical protein 2622078..2622548 Escherichia coli O127:H6 str. E2348/69 7065541 YP_002330043.1 CDS E2348C_2539 NC_011601.1 2622595 2622891 D hypothetical protein 2622595..2622891 Escherichia coli O127:H6 str. E2348/69 7065542 YP_002330044.1 CDS E2348C_2540 NC_011601.1 2622891 2623079 D hypothetical protein 2622891..2623079 Escherichia coli O127:H6 str. E2348/69 7065543 YP_002330045.1 CDS E2348C_2541 NC_011601.1 2623214 2624182 D hypothetical protein 2623214..2624182 Escherichia coli O127:H6 str. E2348/69 7065544 YP_002330046.1 CDS E2348C_2542 NC_011601.1 2624206 2624337 D regulatory protein 2624206..2624337 Escherichia coli O127:H6 str. E2348/69 7065545 YP_002330047.1 CDS E2348C_2543 NC_011601.1 2624322 2624474 D host-killing protein 2624322..2624474 Escherichia coli O127:H6 str. E2348/69 7065546 YP_002330048.1 CDS E2348C_2544 NC_011601.1 2624471 2624629 D hypothetical protein 2624471..2624629 Escherichia coli O127:H6 str. E2348/69 7065547 YP_002330049.1 CDS E2348C_2545 NC_011601.1 2624729 2625436 D hypothetical protein 2624729..2625436 Escherichia coli O127:H6 str. E2348/69 7065548 YP_002330050.1 CDS E2348C_2546 NC_011601.1 2625437 2625904 D hypothetical protein 2625437..2625904 Escherichia coli O127:H6 str. E2348/69 7065549 YP_002330051.1 CDS E2348C_2547 NC_011601.1 2625901 2626407 D single stranded DNA-binding protein 2625901..2626407 Escherichia coli O127:H6 str. E2348/69 7065550 YP_002330052.1 CDS E2348C_2548 NC_011601.1 2626421 2626714 D anti-RecBCD protein 2626421..2626714 Escherichia coli O127:H6 str. E2348/69 7065551 YP_002330053.1 CDS E2348C_2549 NC_011601.1 2626889 2627158 D hypothetical protein 2626889..2627158 Escherichia coli O127:H6 str. E2348/69 7065552 YP_002330054.1 CDS E2348C_2550 NC_011601.1 2627145 2627783 D hypothetical protein 2627145..2627783 Escherichia coli O127:H6 str. E2348/69 7065553 YP_002330055.1 CDS E2348C_2551 NC_011601.1 2627979 2628374 D hypothetical protein 2627979..2628374 Escherichia coli O127:H6 str. E2348/69 7065554 YP_002330056.1 CDS E2348C_2552 NC_011601.1 2628584 2629216 D hypothetical protein 2628584..2629216 Escherichia coli O127:H6 str. E2348/69 7065555 YP_002330057.1 CDS torI NC_011601.1 2629542 2629742 D response regulator inhibitor for tor operon 2629542..2629742 Escherichia coli O127:H6 str. E2348/69 7065556 YP_002330058.1 CDS lacY NC_011601.1 2630270 2631517 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(2630270..2631517) Escherichia coli O127:H6 str. E2348/69 7062223 YP_002330059.1 CDS E2348C_2555 NC_011601.1 2631579 2632502 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(2631579..2632502) Escherichia coli O127:H6 str. E2348/69 7065557 YP_002330060.1 CDS E2348C_2556 NC_011601.1 2632718 2634151 D sucrose-6 phosphate hydrolase 2632718..2634151 Escherichia coli O127:H6 str. E2348/69 7065558 YP_002330061.1 CDS E2348C_2557 NC_011601.1 2634159 2635154 R sucrose operon repressor complement(2634159..2635154) Escherichia coli O127:H6 str. E2348/69 7065559 YP_002330062.1 CDS emrY NC_011601.1 2637052 2638590 R multidrug efflux system complement(2637052..2638590) Escherichia coli O127:H6 str. E2348/69 7065066 YP_002330063.1 CDS emrK NC_011601.1 2638590 2639753 R EmrKY-TolC multidrug resistance efflux pump protein K, membrane fusion protein component complement(2638590..2639753) Escherichia coli O127:H6 str. E2348/69 7063848 YP_002330064.1 CDS evgA NC_011601.1 2640168 2640782 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2640168..2640782 Escherichia coli O127:H6 str. E2348/69 7063847 YP_002330065.1 CDS evgS NC_011601.1 2640787 2644380 D hybrid sensory histidine kinase in two-component regulatory system with EvgA 2640787..2644380 Escherichia coli O127:H6 str. E2348/69 7063903 YP_002330066.1 CDS yfdE NC_011601.1 2644436 2645581 R hypothetical protein complement(2644436..2645581) Escherichia coli O127:H6 str. E2348/69 7063904 YP_002330067.1 CDS yfdV NC_011601.1 2645655 2646599 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(2645655..2646599) Escherichia coli O127:H6 str. E2348/69 7063177 YP_002330068.1 CDS oxc NC_011601.1 2646669 2648363 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(2646669..2648363) Escherichia coli O127:H6 str. E2348/69 7063178 YP_002330069.1 CDS frc NC_011601.1 2648417 2649667 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2648417..2649667) Escherichia coli O127:H6 str. E2348/69 7062896 YP_002330070.1 CDS yfdX NC_011601.1 2650179 2650811 R hypothetical protein complement(2650179..2650811) Escherichia coli O127:H6 str. E2348/69 7061948 YP_002330071.1 CDS ypdI NC_011601.1 2651106 2651381 D lipoprotein involved in colanic acid biosynthesis 2651106..2651381 Escherichia coli O127:H6 str. E2348/69 7063179 YP_002330072.1 CDS yfdY NC_011601.1 2651458 2651700 R hypothetical protein complement(2651458..2651700) Escherichia coli O127:H6 str. E2348/69 7061235 YP_002330073.1 CDS lpxP NC_011601.1 2652053 2652973 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2652053..2652973 Escherichia coli O127:H6 str. E2348/69 7063180 YP_002330074.1 CDS yfdZ NC_011601.1 2653465 2654703 R aminotransferase complement(2653465..2654703) Escherichia coli O127:H6 str. E2348/69 7061099 YP_002330075.1 CDS ypdA NC_011601.1 2655080 2656777 D sensory kinase in two-component system with YpdB 2655080..2656777 Escherichia coli O127:H6 str. E2348/69 7063181 YP_002330076.1 CDS ypdB NC_011601.1 2656792 2657526 D response regulator in two-component system with YpdA 2656792..2657526 Escherichia coli O127:H6 str. E2348/69 7061230 YP_002330077.1 CDS ypdC NC_011601.1 2657539 2658396 D DNA-binding protein 2657539..2658396 Escherichia coli O127:H6 str. E2348/69 7061231 YP_002330078.1 CDS fryA NC_011601.1 2658399 2660894 R fused PTS enzymes: Hpr component/enzyme I component/enzyme IIA component complement(2658399..2660894) Escherichia coli O127:H6 str. E2348/69 7061232 YP_002330079.1 CDS ypdE NC_011601.1 2660919 2661956 R metalloprotein; exoaminopeptidase complement(2660919..2661956) Escherichia coli O127:H6 str. E2348/69 7061970 YP_002330080.1 CDS ypdF NC_011601.1 2661956 2663041 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2661956..2663041) Escherichia coli O127:H6 str. E2348/69 7061233 YP_002330081.1 CDS fryC NC_011601.1 2663056 2664303 R enzyme IIC component of PTS complement(2663056..2664303) Escherichia coli O127:H6 str. E2348/69 7061234 YP_002330082.1 CDS glk NC_011601.1 2664870 2665835 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2664870..2665835) Escherichia coli O127:H6 str. E2348/69 7061971 YP_002330083.1 CDS yfeO NC_011601.1 2666039 2667295 D hypothetical protein 2666039..2667295 Escherichia coli O127:H6 str. E2348/69 7061672 YP_002330084.1 CDS ypeC NC_011601.1 2667410 2667736 D hypothetical protein 2667410..2667736 Escherichia coli O127:H6 str. E2348/69 7064370 YP_002330085.1 CDS mntH NC_011601.1 2667877 2669115 R manganese transport protein MntH complement(2667877..2669115) Escherichia coli O127:H6 str. E2348/69 7061238 YP_002330086.1 CDS nupC NC_011601.1 2669451 2670653 D nucleoside (except guanosine) transporter 2669451..2670653 Escherichia coli O127:H6 str. E2348/69 7063803 YP_002330087.1 CDS yfeA NC_011601.1 2670703 2672892 R diguanylate cyclase complement(2670703..2672892) Escherichia coli O127:H6 str. E2348/69 7065450 YP_002330088.1 CDS yfeC NC_011601.1 2673510 2673869 D DNA-binding transcriptional regulator 2673510..2673869 Escherichia coli O127:H6 str. E2348/69 7062433 YP_002330089.1 CDS yfeD NC_011601.1 2673871 2674263 D DNA-binding transcriptional regulator 2673871..2674263 Escherichia coli O127:H6 str. E2348/69 7064310 YP_002330090.1 CDS gltX NC_011601.1 2674314 2675729 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2674314..2675729) Escherichia coli O127:H6 str. E2348/69 7064366 YP_002330091.1 CDS xapB NC_011601.1 2677646 2678902 R xanthosine transporter complement(2677646..2678902) Escherichia coli O127:H6 str. E2348/69 7064858 YP_002330092.1 CDS xapA NC_011601.1 2678963 2679796 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2678963..2679796) Escherichia coli O127:H6 str. E2348/69 7064857 YP_002330093.1 CDS yfeN NC_011601.1 2680044 2680808 D hypothetical protein 2680044..2680808 Escherichia coli O127:H6 str. E2348/69 7064856 YP_002330094.1 CDS yfeR NC_011601.1 2680847 2681773 R DNA-binding transcriptional regulator complement(2680847..2681773) Escherichia coli O127:H6 str. E2348/69 7064369 YP_002330095.1 CDS yfeH NC_011601.1 2681863 2682861 D hypothetical protein 2681863..2682861 Escherichia coli O127:H6 str. E2348/69 7064371 YP_002330096.1 CDS ypeB NC_011601.1 2682858 2683076 R hypothetical protein complement(2682858..2683076) Escherichia coli O127:H6 str. E2348/69 7064367 YP_002330097.1 CDS ligA NC_011601.1 2683078 2685093 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2683078..2685093) Escherichia coli O127:H6 str. E2348/69 7061237 YP_002330098.1 CDS zipA NC_011601.1 2685164 2686162 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2685164..2686162) Escherichia coli O127:H6 str. E2348/69 7061539 YP_002330099.1 CDS cysZ NC_011601.1 2686392 2687153 D role in sulfur assimilation; sulfate transport protein CysZ 2686392..2687153 Escherichia coli O127:H6 str. E2348/69 7063259 YP_002330100.1 CDS cysK NC_011601.1 2687338 2688309 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2687338..2688309 Escherichia coli O127:H6 str. E2348/69 7065210 YP_002330101.1 CDS ptsH NC_011601.1 2688693 2688950 D PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2688693..2688950 Escherichia coli O127:H6 str. E2348/69 7065202 YP_002330102.1 CDS ptsI NC_011601.1 2688995 2690722 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2688995..2690722 Escherichia coli O127:H6 str. E2348/69 7061339 YP_002330103.1 CDS crr NC_011601.1 2690763 2691272 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2690763..2691272 Escherichia coli O127:H6 str. E2348/69 7063908 YP_002330104.1 CDS pdxK NC_011601.1 2691314 2692165 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2691314..2692165) Escherichia coli O127:H6 str. E2348/69 7062848 YP_002330105.1 CDS yfeK NC_011601.1 2692270 2692638 D hypothetical protein 2692270..2692638 Escherichia coli O127:H6 str. E2348/69 7062943 YP_002330106.1 CDS cysM NC_011601.1 2692641 2693552 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2692641..2693552) Escherichia coli O127:H6 str. E2348/69 7064368 YP_002330107.1 CDS cysA NC_011601.1 2693686 2694783 R sulfate/thiosulfate transporter subunit complement(2693686..2694783) Escherichia coli O127:H6 str. E2348/69 7065203 YP_002330108.1 CDS cysW NC_011601.1 2694773 2695648 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2694773..2695648) Escherichia coli O127:H6 str. E2348/69 7065193 YP_002330109.1 CDS cysU NC_011601.1 2695648 2696481 R sulfate/thiosulfate transporter subunit complement(2695648..2696481) Escherichia coli O127:H6 str. E2348/69 7065209 YP_002330110.1 CDS cysP NC_011601.1 2696481 2697497 R thiosulfate transporter subunit complement(2696481..2697497) Escherichia coli O127:H6 str. E2348/69 7065208 YP_002330111.1 CDS E2348C_2611 NC_011601.1 2697802 2699175 D transposase of ISEc13 2697802..2699175 Escherichia coli O127:H6 str. E2348/69 7061103 YP_002330112.1 CDS ucpA NC_011601.1 2699215 2700006 R short chain dehydrogenase complement(2699215..2700006) Escherichia coli O127:H6 str. E2348/69 7065561 YP_002330113.1 CDS murQ NC_011601.1 2700286 2701182 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2700286..2701182 Escherichia coli O127:H6 str. E2348/69 7062299 YP_002330114.1 CDS murP NC_011601.1 2701186 2702610 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2701186..2702610 Escherichia coli O127:H6 str. E2348/69 7060896 YP_002330115.1 CDS yfeX NC_011601.1 2702790 2703689 R hypothetical protein complement(2702790..2703689) Escherichia coli O127:H6 str. E2348/69 7060895 YP_002330116.1 CDS yfeY NC_011601.1 2703785 2704360 R hypothetical protein complement(2703785..2704360) Escherichia coli O127:H6 str. E2348/69 7064372 YP_002330117.1 CDS yfeZ NC_011601.1 2704421 2704870 R hypothetical protein complement(2704421..2704870) Escherichia coli O127:H6 str. E2348/69 7064373 YP_002330118.1 CDS ypeA NC_011601.1 2704857 2705282 R acetyltransferase complement(2704857..2705282) Escherichia coli O127:H6 str. E2348/69 7064374 YP_002330119.1 CDS amiA NC_011601.1 2705496 2706365 D N-acetylmuramoyl-L-alanine amidase 2705496..2706365 Escherichia coli O127:H6 str. E2348/69 7061236 YP_002330120.1 CDS hemF NC_011601.1 2706369 2707268 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2706369..2707268 Escherichia coli O127:H6 str. E2348/69 7062452 YP_002330121.1 CDS E2348C_2621 NC_011601.1 2707312 2707983 D hypothetical protein 2707312..2707983 Escherichia coli O127:H6 str. E2348/69 7064296 YP_002330122.1 CDS E2348C_2622 NC_011601.1 2707980 2711429 R helicase complement(2707980..2711429) Escherichia coli O127:H6 str. E2348/69 7065562 YP_002330123.1 CDS E2348C_2623 NC_011601.1 2711528 2712790 D hypothetical protein 2711528..2712790 Escherichia coli O127:H6 str. E2348/69 7065563 YP_002330124.1 CDS E2348C_2624 NC_011601.1 2712831 2713148 D hypothetical protein 2712831..2713148 Escherichia coli O127:H6 str. E2348/69 7065564 YP_002330125.1 CDS eutR NC_011601.1 2713227 2714279 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2713227..2714279) Escherichia coli O127:H6 str. E2348/69 7065565 YP_002330126.1 CDS eutK NC_011601.1 2714325 2714825 R carboxysome structural protein with role in ethanolamine utilization complement(2714325..2714825) Escherichia coli O127:H6 str. E2348/69 7063900 YP_002330127.1 CDS eutL NC_011601.1 2714838 2715497 R carboxysome structural protein with role in ethanolamine utilization complement(2714838..2715497) Escherichia coli O127:H6 str. E2348/69 7063894 YP_002330128.1 CDS E2348C_2629 NC_011601.1 2716247 2716894 R repressor protein complement(2716247..2716894) Escherichia coli O127:H6 str. E2348/69 7061173 YP_002330129.1 CDS E2348C_2630 NC_011601.1 2717077 2717313 D DNA-binding protein 2717077..2717313 Escherichia coli O127:H6 str. E2348/69 7065566 YP_002330130.1 CDS E2348C_2631 NC_011601.1 2717313 2719355 D DNA transposition protein 2717313..2719355 Escherichia coli O127:H6 str. E2348/69 7065567 YP_002330131.1 CDS E2348C_2632 NC_011601.1 2719374 2720267 D DNA transposition protein 2719374..2720267 Escherichia coli O127:H6 str. E2348/69 7065568 YP_002330132.1 CDS E2348C_2633 NC_011601.1 2720282 2720506 D hypothetical protein 2720282..2720506 Escherichia coli O127:H6 str. E2348/69 7065569 YP_002330133.1 CDS E2348C_2634 NC_011601.1 2720763 2721407 D hypothetical protein 2720763..2721407 Escherichia coli O127:H6 str. E2348/69 7065570 YP_002330134.1 CDS E2348C_2635 NC_011601.1 2721409 2721642 D hypothetical protein 2721409..2721642 Escherichia coli O127:H6 str. E2348/69 7065571 YP_002330135.1 CDS E2348C_2636 NC_011601.1 2721623 2721814 D hypothetical protein 2721623..2721814 Escherichia coli O127:H6 str. E2348/69 7065572 YP_002330136.1 CDS E2348C_2637 NC_011601.1 2721955 2722173 R hypothetical protein complement(2721955..2722173) Escherichia coli O127:H6 str. E2348/69 7065573 YP_002330137.1 CDS E2348C_2638 NC_011601.1 2722262 2722972 D hypothetical protein 2722262..2722972 Escherichia coli O127:H6 str. E2348/69 7065574 YP_002330138.1 CDS E2348C_2639 NC_011601.1 2722975 2723202 D hypothetical protein 2722975..2723202 Escherichia coli O127:H6 str. E2348/69 7065575 YP_002330139.1 CDS E2348C_2640 NC_011601.1 2723199 2723429 D hypothetical protein 2723199..2723429 Escherichia coli O127:H6 str. E2348/69 7065576 YP_002330140.1 CDS E2348C_2641 NC_011601.1 2723419 2723733 D hypothetical protein 2723419..2723733 Escherichia coli O127:H6 str. E2348/69 7065577 YP_002330141.1 CDS E2348C_2642 NC_011601.1 2723705 2723869 D hypothetical protein 2723705..2723869 Escherichia coli O127:H6 str. E2348/69 7065578 YP_002330142.1 CDS E2348C_2643 NC_011601.1 2723866 2724135 D hypothetical protein 2723866..2724135 Escherichia coli O127:H6 str. E2348/69 7065579 YP_002330143.1 CDS E2348C_2644 NC_011601.1 2724122 2724619 D hypothetical protein 2724122..2724619 Escherichia coli O127:H6 str. E2348/69 7065580 YP_002330144.1 CDS E2348C_2645 NC_011601.1 2724619 2724789 D hypothetical protein 2724619..2724789 Escherichia coli O127:H6 str. E2348/69 7065581 YP_002330145.1 CDS E2348C_2646 NC_011601.1 2724786 2724974 D hypothetical protein 2724786..2724974 Escherichia coli O127:H6 str. E2348/69 7065582 YP_002330146.1 CDS E2348C_2647 NC_011601.1 2725099 2725320 D hypothetical protein 2725099..2725320 Escherichia coli O127:H6 str. E2348/69 7065583 YP_002330147.1 CDS E2348C_2648 NC_011601.1 2725292 2725690 D hypothetical protein 2725292..2725690 Escherichia coli O127:H6 str. E2348/69 7065584 YP_002330148.1 CDS E2348C_2649 NC_011601.1 2725690 2726163 D hypothetical protein 2725690..2726163 Escherichia coli O127:H6 str. E2348/69 7065585 YP_002330149.1 CDS E2348C_2650 NC_011601.1 2726264 2726731 D hypothetical protein 2726264..2726731 Escherichia coli O127:H6 str. E2348/69 7065586 YP_002330150.1 CDS E2348C_2651 NC_011601.1 2726758 2727036 D hypothetical protein 2726758..2727036 Escherichia coli O127:H6 str. E2348/69 7065587 YP_002330151.1 CDS E2348C_2652 NC_011601.1 2727219 2727611 D membrane protein 2727219..2727611 Escherichia coli O127:H6 str. E2348/69 7065588 YP_002330152.1 CDS E2348C_2653 NC_011601.1 2727601 2727897 D holin protein 2727601..2727897 Escherichia coli O127:H6 str. E2348/69 7065589 YP_002330153.1 CDS E2348C_2654 NC_011601.1 2727881 2728426 D hypothetical protein 2727881..2728426 Escherichia coli O127:H6 str. E2348/69 7065590 YP_002330154.1 CDS E2348C_2655 NC_011601.1 2728423 2728605 D hypothetical protein 2728423..2728605 Escherichia coli O127:H6 str. E2348/69 7065591 YP_002330155.1 CDS E2348C_2656 NC_011601.1 2728832 2729332 D DNA-binding protein 2728832..2729332 Escherichia coli O127:H6 str. E2348/69 7065592 YP_002330156.1 CDS E2348C_2657 NC_011601.1 2729379 2730119 D methyltransferase 2729379..2730119 Escherichia coli O127:H6 str. E2348/69 7065593 YP_002330157.1 CDS E2348C_2658 NC_011601.1 2730121 2731761 D hypothetical protein 2730121..2731761 Escherichia coli O127:H6 str. E2348/69 7065594 YP_002330158.1 CDS E2348C_2659 NC_011601.1 2731765 2733360 D hypothetical protein 2731765..2733360 Escherichia coli O127:H6 str. E2348/69 7065595 YP_002330159.1 CDS E2348C_2660 NC_011601.1 2733347 2734513 D head morphogenesis protein 2733347..2734513 Escherichia coli O127:H6 str. E2348/69 7065596 YP_002330160.1 CDS E2348C_2661 NC_011601.1 2734510 2735061 D virion morphogenesis protein 2734510..2735061 Escherichia coli O127:H6 str. E2348/69 7065597 YP_002330161.1 CDS E2348C_2662 NC_011601.1 2735271 2736386 D hypothetical protein 2735271..2736386 Escherichia coli O127:H6 str. E2348/69 7065598 YP_002330162.1 CDS E2348C_2663 NC_011601.1 2736387 2736782 D hypothetical protein 2736387..2736782 Escherichia coli O127:H6 str. E2348/69 7065599 YP_002330163.1 CDS E2348C_2664 NC_011601.1 2736793 2737701 D major head subunit protein 2736793..2737701 Escherichia coli O127:H6 str. E2348/69 7065600 YP_002330164.1 CDS E2348C_2665 NC_011601.1 2737705 2738037 D hypothetical protein 2737705..2738037 Escherichia coli O127:H6 str. E2348/69 7065601 YP_002330165.1 CDS E2348C_2666 NC_011601.1 2738041 2738472 D hypothetical protein 2738041..2738472 Escherichia coli O127:H6 str. E2348/69 7065602 YP_002330166.1 CDS E2348C_2667 NC_011601.1 2738529 2739107 D hypothetical protein 2738529..2739107 Escherichia coli O127:H6 str. E2348/69 7065603 YP_002330167.1 CDS E2348C_2668 NC_011601.1 2739088 2739321 D hypothetical protein 2739088..2739321 Escherichia coli O127:H6 str. E2348/69 7065604 YP_002330168.1 CDS E2348C_2669 NC_011601.1 2739314 2740735 D tail sheath protein 2739314..2740735 Escherichia coli O127:H6 str. E2348/69 7065605 YP_002330169.1 CDS E2348C_2670 NC_011601.1 2740748 2741122 D hypothetical protein 2740748..2741122 Escherichia coli O127:H6 str. E2348/69 7065606 YP_002330170.1 CDS E2348C_2671 NC_011601.1 2741119 2741502 D hypothetical protein 2741119..2741502 Escherichia coli O127:H6 str. E2348/69 7065607 YP_002330171.1 CDS E2348C_2672 NC_011601.1 2741665 2743938 D tail length tape measure protein 2741665..2743938 Escherichia coli O127:H6 str. E2348/69 7065608 YP_002330172.1 CDS E2348C_2673 NC_011601.1 2743938 2745287 D DNA circulation protein 2743938..2745287 Escherichia coli O127:H6 str. E2348/69 7065609 YP_002330173.1 CDS E2348C_2674 NC_011601.1 2745271 2746482 D tail protein 2745271..2746482 Escherichia coli O127:H6 str. E2348/69 7065610 YP_002330174.1 CDS E2348C_2675 NC_011601.1 2746479 2747132 D baseplate assembly protein 2746479..2747132 Escherichia coli O127:H6 str. E2348/69 7065451 YP_002330175.1 CDS E2348C_2676 NC_011601.1 2747186 2747536 D hypothetical protein 2747186..2747536 Escherichia coli O127:H6 str. E2348/69 7065453 YP_002330176.1 CDS E2348C_2677 NC_011601.1 2747536 2748615 D tail protein 2747536..2748615 Escherichia coli O127:H6 str. E2348/69 7065454 YP_002330177.1 CDS E2348C_2678 NC_011601.1 2748619 2749191 D tail protein 2748619..2749191 Escherichia coli O127:H6 str. E2348/69 7065455 YP_002330178.1 CDS E2348C_2679 NC_011601.1 2749275 2749940 D tai fiber protein 2749275..2749940 Escherichia coli O127:H6 str. E2348/69 7065456 YP_002330179.1 CDS E2348C_2680 NC_011601.1 2749940 2750533 D tail fiber assembly protein 2749940..2750533 Escherichia coli O127:H6 str. E2348/69 7065457 YP_002330180.1 CDS E2348C_2681 NC_011601.1 2750505 2750921 R tail fiber assembly protein complement(2750505..2750921) Escherichia coli O127:H6 str. E2348/69 7065458 YP_002330181.1 CDS E2348C_2682 NC_011601.1 2750924 2751430 R hypothetical protein complement(2750924..2751430) Escherichia coli O127:H6 str. E2348/69 7065459 YP_002330182.1 CDS eutB NC_011601.1 2752155 2753516 R ethanolamine ammonia-lyase, large subunit, heavychain complement(2752155..2753516) Escherichia coli O127:H6 str. E2348/69 7065460 YP_002330183.1 CDS E2348C_2685 NC_011601.1 2754775 2756148 R transposase of ISEc13 complement(2754775..2756148) Escherichia coli O127:H6 str. E2348/69 7061104 YP_002330184.1 CDS eutH NC_011601.1 2756488 2757714 R predicter inner membrane protein complement(2756488..2757714) Escherichia coli O127:H6 str. E2348/69 7065461 YP_002330185.1 CDS eutG NC_011601.1 2757931 2759118 R alcohol dehydrogenase in ethanolamineutilization complement(2757931..2759118) Escherichia coli O127:H6 str. E2348/69 7063892 YP_002330186.1 CDS eutJ NC_011601.1 2759108 2759944 R chaperonin, ethanolamine utilization protein EutJ complement(2759108..2759944) Escherichia coli O127:H6 str. E2348/69 7063891 YP_002330187.1 CDS eutE NC_011601.1 2759955 2761358 R aldehyde dehydrogenase complement(2759955..2761358) Escherichia coli O127:H6 str. E2348/69 7063893 YP_002330188.1 CDS eutN NC_011601.1 2761370 2761657 R carboxysome structural protein, ethanolamine utilization protein complement(2761370..2761657) Escherichia coli O127:H6 str. E2348/69 7063890 YP_002330189.1 CDS eutM NC_011601.1 2761764 2762057 R carboxysome structural protein, ethanolamine utilization protein complement(2761764..2762057) Escherichia coli O127:H6 str. E2348/69 7063897 YP_002330190.1 CDS eutD NC_011601.1 2762096 2763112 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2762096..2763112) Escherichia coli O127:H6 str. E2348/69 7063896 YP_002330191.1 CDS eutT NC_011601.1 2763109 2763912 R cobalamin adenosyltransferase in ethanolamine utilization complement(2763109..2763912) Escherichia coli O127:H6 str. E2348/69 7063889 YP_002330192.1 CDS eutQ NC_011601.1 2763909 2764610 R hypothetical protein complement(2763909..2764610) Escherichia coli O127:H6 str. E2348/69 7063902 YP_002330193.1 CDS eutP NC_011601.1 2764585 2765064 R hypothetical protein complement(2764585..2765064) Escherichia coli O127:H6 str. E2348/69 7063899 YP_002330194.1 CDS eutS NC_011601.1 2765077 2765412 R carboxysome structural protein with role in ethanol utilization complement(2765077..2765412) Escherichia coli O127:H6 str. E2348/69 7063898 YP_002330195.1 CDS maeB NC_011601.1 2765704 2767983 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2765704..2767983) Escherichia coli O127:H6 str. E2348/69 7063901 YP_002330196.1 CDS talA NC_011601.1 2768272 2769222 D transaldolase A 2768272..2769222 Escherichia coli O127:H6 str. E2348/69 7065268 YP_002330197.1 CDS tktB NC_011601.1 2769242 2771245 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2769242..2771245 Escherichia coli O127:H6 str. E2348/69 7061749 YP_002330198.1 CDS ypfG NC_011601.1 2771322 2772365 R hypothetical protein complement(2771322..2772365) Escherichia coli O127:H6 str. E2348/69 7061807 YP_002330199.1 CDS nudK NC_011601.1 2772491 2773066 R NUDIX hydrolase complement(2772491..2773066) Escherichia coli O127:H6 str. E2348/69 7061239 YP_002330200.1 CDS aegA NC_011601.1 2773134 2775113 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(2773134..2775113) Escherichia coli O127:H6 str. E2348/69 7065435 YP_002330201.1 CDS narQ NC_011601.1 2775319 2777037 D nitrate/nitrite sensor protein NarQ 2775319..2777037 Escherichia coli O127:H6 str. E2348/69 7062413 YP_002330202.1 CDS E2348C_2704 NC_011601.1 2777124 2780297 R AidA autotransporter-like protein complement(2777124..2780297) Escherichia coli O127:H6 str. E2348/69 7060938 YP_002330203.1 CDS E2348C_2705 NC_011601.1 2780301 2781536 R glycosyl transferase family protein complement(2780301..2781536) Escherichia coli O127:H6 str. E2348/69 7065462 YP_002330204.1 CDS acrD NC_011601.1 2782674 2785787 D aminoglycoside/multidrug efflux system 2782674..2785787 Escherichia coli O127:H6 str. E2348/69 7065463 YP_002330205.1 CDS yffB NC_011601.1 2786326 2786682 D hypothetical protein 2786326..2786682 Escherichia coli O127:H6 str. E2348/69 7062398 YP_002330206.1 CDS dapE NC_011601.1 2786686 2787813 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2786686..2787813 Escherichia coli O127:H6 str. E2348/69 7064375 YP_002330207.1 CDS ypfN NC_011601.1 2787841 2788041 D hypothetical protein 2787841..2788041 Escherichia coli O127:H6 str. E2348/69 7065223 YP_002330208.1 CDS ypfH NC_011601.1 2788122 2788820 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(2788122..2788820) Escherichia coli O127:H6 str. E2348/69 7061243 YP_002330209.1 CDS ypfI NC_011601.1 2788894 2790909 R hydrolase complement(2788894..2790909) Escherichia coli O127:H6 str. E2348/69 7061240 YP_002330210.1 CDS ypfJ NC_011601.1 2790924 2791787 R hypothetical protein complement(2790924..2791787) Escherichia coli O127:H6 str. E2348/69 7061241 YP_002330211.1 CDS purC NC_011601.1 2791955 2792668 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2791955..2792668) Escherichia coli O127:H6 str. E2348/69 7061242 YP_002330212.1 CDS nlpB NC_011601.1 2792881 2793915 R lipoprotein complement(2792881..2793915) Escherichia coli O127:H6 str. E2348/69 7063913 YP_002330213.1 CDS dapA NC_011601.1 2793932 2794810 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2793932..2794810) Escherichia coli O127:H6 str. E2348/69 7065401 YP_002330214.1 CDS gcvR NC_011601.1 2794956 2795528 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2794956..2795528 Escherichia coli O127:H6 str. E2348/69 7065220 YP_002330215.1 CDS bcp NC_011601.1 2795528 2795998 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2795528..2795998 Escherichia coli O127:H6 str. E2348/69 7061645 YP_002330216.1 CDS yfgO NC_011601.1 2796097 2797158 R hypothetical protein complement(2796097..2797158) Escherichia coli O127:H6 str. E2348/69 7062497 YP_002330217.1 CDS yfgC NC_011601.1 2797371 2798834 D peptidase 2797371..2798834 Escherichia coli O127:H6 str. E2348/69 7064386 YP_002330218.1 CDS yfgD NC_011601.1 2798855 2799214 D oxidoreductase 2798855..2799214 Escherichia coli O127:H6 str. E2348/69 7064378 YP_002330219.1 CDS hda NC_011601.1 2799352 2800098 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2799352..2800098) Escherichia coli O127:H6 str. E2348/69 7064379 YP_002330220.1 CDS uraA NC_011601.1 2800148 2801437 R uracil transporter complement(2800148..2801437) Escherichia coli O127:H6 str. E2348/69 7064284 YP_002330221.1 CDS upp NC_011601.1 2801523 2802149 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2801523..2802149) Escherichia coli O127:H6 str. E2348/69 7062329 YP_002330222.1 CDS purM NC_011601.1 2802474 2803511 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2802474..2803511 Escherichia coli O127:H6 str. E2348/69 7062328 YP_002330223.1 CDS purN NC_011601.1 2803511 2804149 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2803511..2804149 Escherichia coli O127:H6 str. E2348/69 7063920 YP_002330224.1 CDS ppk NC_011601.1 2804321 2806387 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2804321..2806387 Escherichia coli O127:H6 str. E2348/69 7063921 YP_002330225.1 CDS ppx NC_011601.1 2806392 2807933 D exopolyphosphatase 2806392..2807933 Escherichia coli O127:H6 str. E2348/69 7061274 YP_002330226.1 CDS yfgF NC_011601.1 2807972 2810215 R hypothetical protein complement(2807972..2810215) Escherichia coli O127:H6 str. E2348/69 7061279 YP_002330227.1 CDS yfgG NC_011601.1 2810567 2810758 D hypothetical protein 2810567..2810758 Escherichia coli O127:H6 str. E2348/69 7064380 YP_002330228.1 CDS yfgH NC_011601.1 2811072 2811587 D outer membrane lipoprotein 2811072..2811587 Escherichia coli O127:H6 str. E2348/69 7064381 YP_002330229.1 CDS yfgI NC_011601.1 2811603 2812142 D hypothetical protein 2811603..2812142 Escherichia coli O127:H6 str. E2348/69 7064382 YP_002330230.1 CDS E2348C_2732 NC_011601.1 2812360 2812842 R endopeptidase complement(2812360..2812842) Escherichia coli O127:H6 str. E2348/69 7061162 YP_002330231.1 CDS E2348C_2733 NC_011601.1 2812368 2812643 R lipoprotein precursor complement(2812368..2812643) Escherichia coli O127:H6 str. E2348/69 7065464 YP_002330232.1 CDS E2348C_2734 NC_011601.1 2812839 2813465 R endolysin complement(2812839..2813465) Escherichia coli O127:H6 str. E2348/69 7065465 YP_002330233.1 CDS E2348C_2735 NC_011601.1 2813455 2813763 R holin protein complement(2813455..2813763) Escherichia coli O127:H6 str. E2348/69 7065466 YP_002330234.1 CDS E2348C_2736 NC_011601.1 2813750 2814154 R membrane protein complement(2813750..2814154) Escherichia coli O127:H6 str. E2348/69 7065467 YP_002330235.1 CDS E2348C_2737 NC_011601.1 2814351 2815358 D hypothetical protein 2814351..2815358 Escherichia coli O127:H6 str. E2348/69 7065468 YP_002330236.1 CDS E2348C_2738 NC_011601.1 2815452 2816525 D acyltransferase 2815452..2816525 Escherichia coli O127:H6 str. E2348/69 7065469 YP_002330237.1 CDS E2348C_2739 NC_011601.1 2816555 2819242 R tail fiber protein complement(2816555..2819242) Escherichia coli O127:H6 str. E2348/69 7065470 YP_002330238.1 CDS E2348C_2740 NC_011601.1 2819441 2819701 D hypothetical protein 2819441..2819701 Escherichia coli O127:H6 str. E2348/69 7065471 YP_002330239.1 CDS E2348C_2741 NC_011601.1 2819902 2822376 R hypothetical protein complement(2819902..2822376) Escherichia coli O127:H6 str. E2348/69 7065472 YP_002330240.1 CDS E2348C_2742 NC_011601.1 2822381 2824183 R hypothetical protein complement(2822381..2824183) Escherichia coli O127:H6 str. E2348/69 7065473 YP_002330241.1 CDS E2348C_2743 NC_011601.1 2824180 2826690 R hypothetical protein complement(2824180..2826690) Escherichia coli O127:H6 str. E2348/69 7065474 YP_002330242.1 CDS E2348C_2744 NC_011601.1 2826703 2827245 R hypothetical protein complement(2826703..2827245) Escherichia coli O127:H6 str. E2348/69 7065475 YP_002330243.1 CDS E2348C_2745 NC_011601.1 2827245 2827709 R hypothetical protein complement(2827245..2827709) Escherichia coli O127:H6 str. E2348/69 7065476 YP_002330244.1 CDS E2348C_2746 NC_011601.1 2827709 2830186 R hypothetical protein complement(2827709..2830186) Escherichia coli O127:H6 str. E2348/69 7065477 YP_002330245.1 CDS E2348C_2747 NC_011601.1 2830186 2830791 R hypothetical protein complement(2830186..2830791) Escherichia coli O127:H6 str. E2348/69 7065478 YP_002330246.1 CDS E2348C_2748 NC_011601.1 2830791 2831114 R hypothetical protein complement(2830791..2831114) Escherichia coli O127:H6 str. E2348/69 7065479 YP_002330247.1 CDS E2348C_2749 NC_011601.1 2831166 2831546 R hypothetical protein complement(2831166..2831546) Escherichia coli O127:H6 str. E2348/69 7065480 YP_002330248.1 CDS E2348C_2750 NC_011601.1 2831557 2831997 R hypothetical protein complement(2831557..2831997) Escherichia coli O127:H6 str. E2348/69 7065481 YP_002330249.1 CDS E2348C_2751 NC_011601.1 2832049 2833035 R hypothetical protein complement(2832049..2833035) Escherichia coli O127:H6 str. E2348/69 7065482 YP_002330250.1 CDS E2348C_2752 NC_011601.1 2833050 2833760 R endoprotease complement(2833050..2833760) Escherichia coli O127:H6 str. E2348/69 7065483 YP_002330251.1 CDS E2348C_2753 NC_011601.1 2833775 2834320 R protease complement(2833775..2834320) Escherichia coli O127:H6 str. E2348/69 7065484 YP_002330252.1 CDS E2348C_2754 NC_011601.1 2834317 2834616 R hypothetical protein complement(2834317..2834616) Escherichia coli O127:H6 str. E2348/69 7065485 YP_002330253.1 CDS E2348C_2755 NC_011601.1 2834613 2836283 R phage head-tail connector protein complement(2834613..2836283) Escherichia coli O127:H6 str. E2348/69 7065486 YP_002330254.1 CDS E2348C_2756 NC_011601.1 2836298 2836504 R hypothetical protein complement(2836298..2836504) Escherichia coli O127:H6 str. E2348/69 7065487 YP_002330255.1 CDS E2348C_2757 NC_011601.1 2837376 2837807 D hypothetical protein 2837376..2837807 Escherichia coli O127:H6 str. E2348/69 7061151 YP_002330256.1 CDS E2348C_2758 NC_011601.1 2837851 2839332 R terminase large subunit complement(2837851..2839332) Escherichia coli O127:H6 str. E2348/69 7065489 YP_002330257.1 CDS E2348C_2759 NC_011601.1 2839329 2839922 R terminase, small subunit complement(2839329..2839922) Escherichia coli O127:H6 str. E2348/69 7065490 YP_002330258.1 CDS E2348C_2760 NC_011601.1 2840026 2840364 R hypothetical protein complement(2840026..2840364) Escherichia coli O127:H6 str. E2348/69 7065491 YP_002330259.1 CDS E2348C_2761 NC_011601.1 2840479 2840901 R hypothetical protein complement(2840479..2840901) Escherichia coli O127:H6 str. E2348/69 7065492 YP_002330260.1 CDS E2348C_2762 NC_011601.1 2840898 2841194 R hypothetical protein complement(2840898..2841194) Escherichia coli O127:H6 str. E2348/69 7065493 YP_002330261.1 CDS E2348C_2763 NC_011601.1 2841205 2841411 R hypothetical protein complement(2841205..2841411) Escherichia coli O127:H6 str. E2348/69 7065494 YP_002330262.1 CDS E2348C_2764 NC_011601.1 2841377 2841643 R hypothetical protein complement(2841377..2841643) Escherichia coli O127:H6 str. E2348/69 7065495 YP_002330263.1 CDS E2348C_2765 NC_011601.1 2841662 2841964 R hypothetical protein complement(2841662..2841964) Escherichia coli O127:H6 str. E2348/69 7065496 YP_002330264.1 CDS E2348C_2766 NC_011601.1 2842026 2842367 R hypothetical protein complement(2842026..2842367) Escherichia coli O127:H6 str. E2348/69 7065497 YP_002330265.1 CDS E2348C_2767 NC_011601.1 2842485 2843225 R replication protein complement(2842485..2843225) Escherichia coli O127:H6 str. E2348/69 7065498 YP_002330266.1 CDS E2348C_2768 NC_011601.1 2843267 2844073 R primosomal protein complement(2843267..2844073) Escherichia coli O127:H6 str. E2348/69 7065499 YP_002330267.1 CDS E2348C_2769 NC_011601.1 2844089 2844289 R hypothetical protein complement(2844089..2844289) Escherichia coli O127:H6 str. E2348/69 7065500 YP_002330268.1 CDS E2348C_2770 NC_011601.1 2844437 2844670 R hypothetical protein complement(2844437..2844670) Escherichia coli O127:H6 str. E2348/69 7065501 YP_002330269.1 CDS E2348C_2771 NC_011601.1 2844826 2845422 D repressor protein 2844826..2845422 Escherichia coli O127:H6 str. E2348/69 7065502 YP_002330270.1 CDS E2348C_2772 NC_011601.1 2845647 2845796 D hypothetical protein 2845647..2845796 Escherichia coli O127:H6 str. E2348/69 7065503 YP_002330271.1 CDS E2348C_2773 NC_011601.1 2845793 2846752 D hypothetical protein 2845793..2846752 Escherichia coli O127:H6 str. E2348/69 7065504 YP_002330272.1 CDS E2348C_2774 NC_011601.1 2846760 2847062 D hypothetical protein 2846760..2847062 Escherichia coli O127:H6 str. E2348/69 7065505 YP_002330273.1 CDS E2348C_2775 NC_011601.1 2847059 2847880 D exonuclease VIII/RecE-like protein 2847059..2847880 Escherichia coli O127:H6 str. E2348/69 7065506 YP_002330274.1 CDS E2348C_2776 NC_011601.1 2847877 2848758 D RecT family protein 2847877..2848758 Escherichia coli O127:H6 str. E2348/69 7065507 YP_002330275.1 CDS E2348C_2777 NC_011601.1 2848805 2849053 D transcriptional regulator, AlpA family 2848805..2849053 Escherichia coli O127:H6 str. E2348/69 7065508 YP_002330276.1 CDS E2348C_2778 NC_011601.1 2849163 2849462 D hypothetical protein 2849163..2849462 Escherichia coli O127:H6 str. E2348/69 7065509 YP_002330277.1 CDS E2348C_2779 NC_011601.1 2849610 2850323 D hypothetical protein 2849610..2850323 Escherichia coli O127:H6 str. E2348/69 7065510 YP_002330278.1 CDS E2348C_2780 NC_011601.1 2850320 2850913 D adenine methylase 2850320..2850913 Escherichia coli O127:H6 str. E2348/69 7065511 YP_002330279.1 CDS E2348C_2781 NC_011601.1 2851086 2852339 R integrase complement(2851086..2852339) Escherichia coli O127:H6 str. E2348/69 7065512 YP_002330280.1 CDS guaA NC_011601.1 2852532 2854109 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2852532..2854109) Escherichia coli O127:H6 str. E2348/69 7065513 YP_002330281.1 CDS guaB NC_011601.1 2854178 2855644 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2854178..2855644) Escherichia coli O127:H6 str. E2348/69 7064270 YP_002330282.1 CDS xseA NC_011601.1 2855806 2857179 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2855806..2857179 Escherichia coli O127:H6 str. E2348/69 7064271 YP_002330283.1 CDS E2348C_2785 NC_011601.1 2857508 2859790 R RatA-like protein complement(2857508..2859790) Escherichia coli O127:H6 str. E2348/69 7064958 YP_002330284.1 CDS E2348C_2786 NC_011601.1 2859900 2860856 R outer membrane protein complement(2859900..2860856) Escherichia coli O127:H6 str. E2348/69 7065514 YP_002330285.1 CDS E2348C_2787 NC_011601.1 2860904 2863039 R intimin-like protein complement(2860904..2863039) Escherichia coli O127:H6 str. E2348/69 7065515 YP_002330286.1 CDS E2348C_2788 NC_011601.1 2863959 2864558 R hypothetical protein complement(2863959..2864558) Escherichia coli O127:H6 str. E2348/69 7065516 YP_002330287.1 CDS E2348C_2789 NC_011601.1 2865065 2865724 R hypothetical protein complement(2865065..2865724) Escherichia coli O127:H6 str. E2348/69 7065517 YP_002330288.1 CDS E2348C_2790 NC_011601.1 2865726 2866646 R hypothetical protein complement(2865726..2866646) Escherichia coli O127:H6 str. E2348/69 7065518 YP_002330289.1 CDS E2348C_2791 NC_011601.1 2867992 2868990 R hypothetical protein complement(2867992..2868990) Escherichia coli O127:H6 str. E2348/69 7065519 YP_002330290.1 CDS E2348C_2792 NC_011601.1 2869043 2869738 R hypothetical protein complement(2869043..2869738) Escherichia coli O127:H6 str. E2348/69 7065520 YP_002330291.1 CDS E2348C_2793 NC_011601.1 2869825 2871087 R integrase complement(2869825..2871087) Escherichia coli O127:H6 str. E2348/69 7065521 YP_002330292.1 CDS engA NC_011601.1 2871313 2872785 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2871313..2872785) Escherichia coli O127:H6 str. E2348/69 7065522 YP_002330293.1 CDS yfgL NC_011601.1 2872903 2874081 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2872903..2874081) Escherichia coli O127:H6 str. E2348/69 7065012 YP_002330294.1 CDS yfgM NC_011601.1 2874092 2874712 R hypothetical protein complement(2874092..2874712) Escherichia coli O127:H6 str. E2348/69 7064384 YP_002330295.1 CDS hisS NC_011601.1 2874730 2876004 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2874730..2876004) Escherichia coli O127:H6 str. E2348/69 7064385 YP_002330296.1 CDS ispG NC_011601.1 2876115 2877233 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2876115..2877233) Escherichia coli O127:H6 str. E2348/69 7062758 YP_002330297.1 CDS yfgA NC_011601.1 2877260 2878267 R cytoskeletal protein RodZ complement(2877260..2878267) Escherichia coli O127:H6 str. E2348/69 7063556 YP_002330298.1 CDS yfgB NC_011601.1 2878552 2879706 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2878552..2879706) Escherichia coli O127:H6 str. E2348/69 7064376 YP_002330299.1 CDS ndk NC_011601.1 2879856 2880287 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2879856..2880287) Escherichia coli O127:H6 str. E2348/69 7064377 YP_002330300.1 CDS pbpC NC_011601.1 2880436 2882748 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2880436..2882748) Escherichia coli O127:H6 str. E2348/69 7065377 YP_002330301.1 CDS yfhM NC_011601.1 2882749 2887710 R hypothetical protein complement(2882749..2887710) Escherichia coli O127:H6 str. E2348/69 7062913 YP_002330302.1 CDS sseA NC_011601.1 2887917 2888762 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2887917..2888762 Escherichia coli O127:H6 str. E2348/69 7064392 YP_002330303.1 CDS sseB NC_011601.1 2889255 2890031 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2889255..2890031) Escherichia coli O127:H6 str. E2348/69 7064598 YP_002330304.1 CDS pepB NC_011601.1 2890174 2891457 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase complement(2890174..2891457) Escherichia coli O127:H6 str. E2348/69 7062763 YP_002330305.1 CDS iscX NC_011601.1 2891516 2891716 R hypothetical protein complement(2891516..2891716) Escherichia coli O127:H6 str. E2348/69 7061179 YP_002330306.1 CDS fdx NC_011601.1 2891728 2892063 R [2Fe-2S] ferredoxin complement(2891728..2892063) Escherichia coli O127:H6 str. E2348/69 7063550 YP_002330307.1 CDS hscA NC_011601.1 2892065 2893915 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2892065..2893915) Escherichia coli O127:H6 str. E2348/69 7062095 YP_002330308.1 CDS hscB NC_011601.1 2893932 2894447 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2893932..2894447) Escherichia coli O127:H6 str. E2348/69 7062180 YP_002330309.1 CDS iscA NC_011601.1 2894543 2894866 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2894543..2894866) Escherichia coli O127:H6 str. E2348/69 7062181 YP_002330310.1 CDS iscU NC_011601.1 2894883 2895269 R scaffold protein complement(2894883..2895269) Escherichia coli O127:H6 str. E2348/69 7063546 YP_002330311.1 CDS iscS NC_011601.1 2895297 2896511 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2895297..2896511) Escherichia coli O127:H6 str. E2348/69 7063549 YP_002330312.1 CDS iscR NC_011601.1 2896623 2897111 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2896623..2897111) Escherichia coli O127:H6 str. E2348/69 7063548 YP_002330313.1 CDS trmJ NC_011601.1 2897381 2898121 R methyltransferase complement(2897381..2898121) Escherichia coli O127:H6 str. E2348/69 7063547 YP_002330314.1 CDS suhB NC_011601.1 2898240 2899043 D inositol monophosphatase 2898240..2899043 Escherichia coli O127:H6 str. E2348/69 7062245 YP_002330315.1 CDS yfhR NC_011601.1 2899188 2900042 D peptidase 2899188..2900042 Escherichia coli O127:H6 str. E2348/69 7061742 YP_002330316.1 CDS csiE NC_011601.1 2900233 2901513 D stationary phase inducible protein CsiE 2900233..2901513 Escherichia coli O127:H6 str. E2348/69 7064393 YP_002330317.1 CDS hcaT NC_011601.1 2901505 2902644 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(2901505..2902644) Escherichia coli O127:H6 str. E2348/69 7062858 YP_002330318.1 CDS yphA NC_011601.1 2902968 2903435 D hypothetical protein 2902968..2903435 Escherichia coli O127:H6 str. E2348/69 7064280 YP_002330319.1 CDS yphB NC_011601.1 2903595 2904467 R hypothetical protein complement(2903595..2904467) Escherichia coli O127:H6 str. E2348/69 7061244 YP_002330320.1 CDS yphC NC_011601.1 2904479 2905540 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(2904479..2905540) Escherichia coli O127:H6 str. E2348/69 7061245 YP_002330321.1 CDS yphD NC_011601.1 2905606 2906604 R sugar transporter subunit: membrane component of ABC superfamily complement(2905606..2906604) Escherichia coli O127:H6 str. E2348/69 7061246 YP_002330322.1 CDS yphE NC_011601.1 2906629 2908140 R fused sugar transporter subunits of ABC superfamily: ATP-binding components complement(2906629..2908140) Escherichia coli O127:H6 str. E2348/69 7061247 YP_002330323.1 CDS yphF NC_011601.1 2908163 2909146 R sugar transporter subunit: periplasmic-binding component of ABC superfamily complement(2908163..2909146) Escherichia coli O127:H6 str. E2348/69 7061248 YP_002330324.1 CDS yphG NC_011601.1 2909243 2912524 R hypothetical protein complement(2909243..2912524) Escherichia coli O127:H6 str. E2348/69 7061249 YP_002330325.1 CDS yphH NC_011601.1 2912642 2913835 D DNA-binding transcriptional regulator 2912642..2913835 Escherichia coli O127:H6 str. E2348/69 7061250 YP_002330326.1 CDS glyA NC_011601.1 2913899 2915152 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2913899..2915152) Escherichia coli O127:H6 str. E2348/69 7061251 YP_002330327.1 CDS hmp NC_011601.1 2915480 2916670 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2915480..2916670 Escherichia coli O127:H6 str. E2348/69 7061720 YP_002330328.1 CDS glnB NC_011601.1 2916715 2917053 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2916715..2917053) Escherichia coli O127:H6 str. E2348/69 7062159 YP_002330329.1 CDS qseF NC_011601.1 2917114 2918448 R DNA-binding response regulator in two-component system with QseE complement(2917114..2918448) Escherichia coli O127:H6 str. E2348/69 7061677 YP_002330330.1 CDS yfhG NC_011601.1 2918438 2919151 R hypothetical protein complement(2918438..2919151) Escherichia coli O127:H6 str. E2348/69 7063942 YP_002330331.1 CDS qseE NC_011601.1 2919316 2920743 R sensory kinase in two-component system with QseF complement(2919316..2920743) Escherichia coli O127:H6 str. E2348/69 7064389 YP_002330332.1 CDS purL NC_011601.1 2921319 2925206 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2921319..2925206) Escherichia coli O127:H6 str. E2348/69 7062759 YP_002330333.1 CDS yfhD NC_011601.1 2925603 2927021 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2925603..2927021 Escherichia coli O127:H6 str. E2348/69 7063919 YP_002330334.1 CDS tadA NC_011601.1 2927018 2927521 R tRNA-specific adenosine deaminase complement(2927018..2927521) Escherichia coli O127:H6 str. E2348/69 7064388 YP_002330335.1 CDS yfhB NC_011601.1 2927579 2928214 R hypothetical protein complement(2927579..2928214) Escherichia coli O127:H6 str. E2348/69 7061747 YP_002330336.1 CDS yfhH NC_011601.1 2928423 2929271 D DNA-binding transcriptional regulator 2928423..2929271 Escherichia coli O127:H6 str. E2348/69 7064387 YP_002330337.1 CDS yfhL NC_011601.1 2929327 2929587 D (4Fe-4S)-binding protein 2929327..2929587 Escherichia coli O127:H6 str. E2348/69 7064390 YP_002330338.1 CDS acpS NC_011601.1 2930282 2930662 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2930282..2930662) Escherichia coli O127:H6 str. E2348/69 7064600 YP_002330339.1 CDS pdxJ NC_011601.1 2930662 2931393 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2930662..2931393) Escherichia coli O127:H6 str. E2348/69 7062394 YP_002330340.1 CDS recO NC_011601.1 2931405 2932133 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2931405..2932133) Escherichia coli O127:H6 str. E2348/69 7062942 YP_002330341.1 CDS era NC_011601.1 2932145 2933050 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2932145..2933050) Escherichia coli O127:H6 str. E2348/69 7063983 YP_002330342.1 CDS rnc NC_011601.1 2933047 2933727 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2933047..2933727) Escherichia coli O127:H6 str. E2348/69 7063865 YP_002330343.1 CDS lepB NC_011601.1 2933998 2934972 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2933998..2934972) Escherichia coli O127:H6 str. E2348/69 7060848 YP_002330344.1 CDS lepA NC_011601.1 2934988 2936787 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2934988..2936787) Escherichia coli O127:H6 str. E2348/69 7061519 YP_002330345.1 CDS rseC NC_011601.1 2936985 2937464 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2936985..2937464) Escherichia coli O127:H6 str. E2348/69 7061518 YP_002330346.1 CDS rseB NC_011601.1 2937461 2938417 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2937461..2938417) Escherichia coli O127:H6 str. E2348/69 7064552 YP_002330347.1 CDS rseA NC_011601.1 2938417 2939067 R anti-RNA polymerase sigma factor SigE complement(2938417..2939067) Escherichia coli O127:H6 str. E2348/69 7064551 YP_002330348.1 CDS rpoE NC_011601.1 2939100 2939675 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2939100..2939675) Escherichia coli O127:H6 str. E2348/69 7064550 YP_002330349.1 CDS nadB NC_011601.1 2940083 2941705 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2940083..2941705 Escherichia coli O127:H6 str. E2348/69 7061867 YP_002330350.1 CDS yfiC NC_011601.1 2941690 2942427 R S-adenosyl-L-methionine-dependent methyltransferase complement(2941690..2942427) Escherichia coli O127:H6 str. E2348/69 7060905 YP_002330351.1 CDS srmB NC_011601.1 2942559 2943893 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2942559..2943893 Escherichia coli O127:H6 str. E2348/69 7064395 YP_002330352.1 CDS yfiE NC_011601.1 2943926 2944807 R DNA-binding transcriptional regulator complement(2943926..2944807) Escherichia coli O127:H6 str. E2348/69 7062754 YP_002330353.1 CDS yfiD NC_011601.1 2945552 2945935 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2945552..2945935) Escherichia coli O127:H6 str. E2348/69 7065079 YP_002330354.1 CDS ung NC_011601.1 2946240 2946929 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2946240..2946929 Escherichia coli O127:H6 str. E2348/69 7064396 YP_002330355.1 CDS yfiF NC_011601.1 2946977 2948014 R methyltransferase complement(2946977..2948014) Escherichia coli O127:H6 str. E2348/69 7062326 YP_002330356.1 CDS trxC NC_011601.1 2948221 2948640 D thioredoxin 2 2948221..2948640 Escherichia coli O127:H6 str. E2348/69 7064398 YP_002330357.1 CDS yfiP NC_011601.1 2948709 2949407 D hypothetical protein 2948709..2949407 Escherichia coli O127:H6 str. E2348/69 7062269 YP_002330358.1 CDS yfiQ NC_011601.1 2949439 2952099 D fused acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit 2949439..2952099 Escherichia coli O127:H6 str. E2348/69 7064403 YP_002330359.1 CDS pssA NC_011601.1 2952213 2953568 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2952213..2953568 Escherichia coli O127:H6 str. E2348/69 7064404 YP_002330360.1 CDS yfiM NC_011601.1 2953665 2953937 D hypothetical protein 2953665..2953937 Escherichia coli O127:H6 str. E2348/69 7061328 YP_002330361.1 CDS kgtP NC_011601.1 2953934 2955232 R alpha-ketoglutarate transporter complement(2953934..2955232) Escherichia coli O127:H6 str. E2348/69 7064401 YP_002330362.1 CDS clpB NC_011601.1 2962514 2965087 R protein disaggregation chaperone complement(2962514..2965087) Escherichia coli O127:H6 str. E2348/69 7064547 YP_002330363.1 CDS yfiH NC_011601.1 2965217 2965948 R hypothetical protein complement(2965217..2965948) Escherichia coli O127:H6 str. E2348/69 7064601 YP_002330364.1 CDS rluD NC_011601.1 2965945 2966925 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2965945..2966925) Escherichia coli O127:H6 str. E2348/69 7064399 YP_002330365.1 CDS yfiO NC_011601.1 2967060 2967797 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2967060..2967797 Escherichia coli O127:H6 str. E2348/69 7060841 YP_002330366.1 CDS raiA NC_011601.1 2969168 2969509 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2969168..2969509 Escherichia coli O127:H6 str. E2348/69 7065524 YP_002330368.1 CDS pheA NC_011601.1 2969759 2970919 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2969759..2970919 Escherichia coli O127:H6 str. E2348/69 7060721 YP_002330369.1 CDS tyrA NC_011601.1 2970962 2972083 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2970962..2972083) Escherichia coli O127:H6 str. E2348/69 7060720 YP_002330370.1 CDS aroF NC_011601.1 2972094 2973164 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2972094..2973164) Escherichia coli O127:H6 str. E2348/69 7062283 YP_002330371.1 CDS yfiL NC_011601.1 2973378 2973740 D hypothetical protein 2973378..2973740 Escherichia coli O127:H6 str. E2348/69 7061394 YP_002330372.1 CDS yfiR NC_011601.1 2973888 2974406 D hypothetical protein 2973888..2974406 Escherichia coli O127:H6 str. E2348/69 7064400 YP_002330373.1 CDS yfiN NC_011601.1 2974396 2975622 D hypothetical protein 2974396..2975622 Escherichia coli O127:H6 str. E2348/69 7064405 YP_002330374.1 CDS yfiB NC_011601.1 2975638 2976120 D outer membrane lipoprotein 2975638..2976120 Escherichia coli O127:H6 str. E2348/69 7064402 YP_002330375.1 CDS E2348C_2880 NC_011601.1 2976324 2977253 R hypothetical protein complement(2976324..2977253) Escherichia coli O127:H6 str. E2348/69 7061163 YP_002330376.1 CDS E2348C_2883 NC_011601.1 2978079 2978681 D tail fibre assembly protein 2978079..2978681 Escherichia coli O127:H6 str. E2348/69 7065527 YP_002330377.1 CDS E2348C_2884 NC_011601.1 2978653 2979093 R hypothetical protein complement(2978653..2979093) Escherichia coli O127:H6 str. E2348/69 7065528 YP_002330378.1 CDS E2348C_2886 NC_011601.1 2979534 2980112 D DNA-invertase 2979534..2980112 Escherichia coli O127:H6 str. E2348/69 7065530 YP_002330379.1 CDS E2348C_2887 NC_011601.1 2980177 2981364 D tail sheath protein 2980177..2981364 Escherichia coli O127:H6 str. E2348/69 7065531 YP_002330380.1 CDS E2348C_2888 NC_011601.1 2981377 2981895 D tail tube protein 2981377..2981895 Escherichia coli O127:H6 str. E2348/69 7062544 YP_002330381.1 CDS E2348C_2889 NC_011601.1 2981958 2982230 D tail protein 2981958..2982230 Escherichia coli O127:H6 str. E2348/69 7062545 YP_002330382.1 CDS E2348C_2890 NC_011601.1 2982384 2984813 D tail length tape measure protein 2982384..2984813 Escherichia coli O127:H6 str. E2348/69 7062546 YP_002330383.1 CDS E2348C_2891 NC_011601.1 2984825 2985289 D tail fiber protein 2984825..2985289 Escherichia coli O127:H6 str. E2348/69 7062547 YP_002330384.1 CDS E2348C_2892 NC_011601.1 2985292 2986464 D late gene regulator 2985292..2986464 Escherichia coli O127:H6 str. E2348/69 7062548 YP_002330385.1 CDS E2348C_2893 NC_011601.1 2986541 2986759 D DNA-binding transcriptional regulator 2986541..2986759 Escherichia coli O127:H6 str. E2348/69 7062549 YP_002330386.1 CDS E2348C_2894 NC_011601.1 2986797 2987519 R hypothetical protein complement(2986797..2987519) Escherichia coli O127:H6 str. E2348/69 7062550 YP_002330387.1 CDS rplS NC_011601.1 2987725 2988072 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2987725..2988072) Escherichia coli O127:H6 str. E2348/69 7062551 YP_002330388.1 CDS trmD NC_011601.1 2988114 2988881 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(2988114..2988881) Escherichia coli O127:H6 str. E2348/69 7061846 YP_002330389.1 CDS rimM NC_011601.1 2988912 2989460 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2988912..2989460) Escherichia coli O127:H6 str. E2348/69 7062242 YP_002330390.1 CDS rpsP NC_011601.1 2989479 2989727 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2989479..2989727) Escherichia coli O127:H6 str. E2348/69 7060831 YP_002330391.1 CDS ffh NC_011601.1 2989864 2991225 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2989864..2991225) Escherichia coli O127:H6 str. E2348/69 7061888 YP_002330392.1 CDS ypjD NC_011601.1 2991317 2992183 D hypothetical protein 2991317..2992183 Escherichia coli O127:H6 str. E2348/69 7062107 YP_002330393.1 CDS yfjD NC_011601.1 2992228 2993490 D hypothetical protein 2992228..2993490 Escherichia coli O127:H6 str. E2348/69 7061252 YP_002330394.1 CDS grpE NC_011601.1 2993545 2994138 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2993545..2994138) Escherichia coli O127:H6 str. E2348/69 7064406 YP_002330395.1 CDS ppnK NC_011601.1 2994261 2995139 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2994261..2995139 Escherichia coli O127:H6 str. E2348/69 7064245 YP_002330396.1 CDS recN NC_011601.1 2995225 2996886 D recombination and repair protein 2995225..2996886 Escherichia coli O127:H6 str. E2348/69 7060909 YP_002330397.1 CDS smpA NC_011601.1 2997035 2997376 D hypothetical protein 2997035..2997376 Escherichia coli O127:H6 str. E2348/69 7063982 YP_002330398.1 CDS yfjF NC_011601.1 2997438 2997728 R hypothetical protein complement(2997438..2997728) Escherichia coli O127:H6 str. E2348/69 7062729 YP_002330399.1 CDS yfjG NC_011601.1 2997718 2998194 R hypothetical protein complement(2997718..2998194) Escherichia coli O127:H6 str. E2348/69 7064407 YP_002330400.1 CDS smpB NC_011601.1 2998326 2998808 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2998326..2998808 Escherichia coli O127:H6 str. E2348/69 7064408 YP_002330401.1 CDS E2348C_2913 NC_011601.1 3003890 3004108 D hypothetical protein 3003890..3004108 Escherichia coli O127:H6 str. E2348/69 7062555 YP_002330402.1 CDS E2348C_2914 NC_011601.1 3004369 3004740 D hypothetical protein 3004369..3004740 Escherichia coli O127:H6 str. E2348/69 7062556 YP_002330403.1 CDS espC NC_011601.1 3005494 3009411 R serine protease complement(3005494..3009411) Escherichia coli O127:H6 str. E2348/69 7062557 YP_002330404.1 CDS E2348C_2916 NC_011601.1 3009981 3011153 R T3SS secreted effector EspG-like protein complement(3009981..3011153) Escherichia coli O127:H6 str. E2348/69 7063879 YP_002330405.1 CDS E2348C_2917 NC_011601.1 3011232 3011396 R hypothetical protein complement(3011232..3011396) Escherichia coli O127:H6 str. E2348/69 7062558 YP_002330406.1 CDS E2348C_2918 NC_011601.1 3011977 3012462 D hypothetical protein 3011977..3012462 Escherichia coli O127:H6 str. E2348/69 7062559 YP_002330407.1 CDS E2348C_2919 NC_011601.1 3013615 3013785 D hypothetical protein 3013615..3013785 Escherichia coli O127:H6 str. E2348/69 7062560 YP_002330408.1 CDS E2348C_2920 NC_011601.1 3013792 3013992 R hypothetical protein complement(3013792..3013992) Escherichia coli O127:H6 str. E2348/69 7062561 YP_002330409.1 CDS E2348C_2921 NC_011601.1 3014161 3014541 D hypothetical protein 3014161..3014541 Escherichia coli O127:H6 str. E2348/69 7062562 YP_002330410.1 CDS csiD NC_011601.1 3014849 3015826 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3014849..3015826 Escherichia coli O127:H6 str. E2348/69 7062563 YP_002330411.1 CDS ihgO NC_011601.1 3015846 3017114 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3015846..3017114 Escherichia coli O127:H6 str. E2348/69 7062857 YP_002330412.1 CDS gabD NC_011601.1 3017137 3018585 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3017137..3018585 Escherichia coli O127:H6 str. E2348/69 7063522 YP_002330413.1 CDS gabT NC_011601.1 3018599 3019879 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3018599..3019879 Escherichia coli O127:H6 str. E2348/69 7061606 YP_002330414.1 CDS gabP NC_011601.1 3020116 3021516 D gamma-aminobutyrate transporter 3020116..3021516 Escherichia coli O127:H6 str. E2348/69 7061608 YP_002330415.1 CDS csiR NC_011601.1 3021537 3022199 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3021537..3022199 Escherichia coli O127:H6 str. E2348/69 7061607 YP_002330416.1 CDS ygaU NC_011601.1 3022200 3022649 R LysM domain/BON superfamily protein complement(3022200..3022649) Escherichia coli O127:H6 str. E2348/69 7062859 YP_002330417.1 CDS yqaE NC_011601.1 3022733 3022891 R membrane protein complement(3022733..3022891) Escherichia coli O127:H6 str. E2348/69 7064414 YP_002330418.1 CDS ygaV NC_011601.1 3023074 3023373 D DNA-binding transcriptional regulator 3023074..3023373 Escherichia coli O127:H6 str. E2348/69 7061255 YP_002330419.1 CDS ygaP NC_011601.1 3023383 3023907 D inner membrane protein with hydrolase activity 3023383..3023907 Escherichia coli O127:H6 str. E2348/69 7064415 YP_002330420.1 CDS stpA NC_011601.1 3023954 3024358 R DNA binding protein complement(3023954..3024358) Escherichia coli O127:H6 str. E2348/69 7064413 YP_002330421.1 CDS ygaW NC_011601.1 3025025 3025474 D hypothetical protein 3025025..3025474 Escherichia coli O127:H6 str. E2348/69 7062776 YP_002330422.1 CDS ygaC NC_011601.1 3025511 3025855 R hypothetical protein complement(3025511..3025855) Escherichia coli O127:H6 str. E2348/69 7064416 YP_002330423.1 CDS ygaM NC_011601.1 3026007 3026336 D hypothetical protein 3026007..3026336 Escherichia coli O127:H6 str. E2348/69 7064409 YP_002330424.1 CDS E2348C_2937 NC_011601.1 3027813 3028244 D hypothetical protein 3027813..3028244 Escherichia coli O127:H6 str. E2348/69 7062564 YP_002330425.1 CDS nrdH NC_011601.1 3028453 3028698 D glutaredoxin-like protein 3028453..3028698 Escherichia coli O127:H6 str. E2348/69 7062565 YP_002330426.1 CDS nrdI NC_011601.1 3028695 3029105 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3028695..3029105 Escherichia coli O127:H6 str. E2348/69 7065415 YP_002330427.1 CDS nrdE NC_011601.1 3029078 3031222 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3029078..3031222 Escherichia coli O127:H6 str. E2348/69 7065416 YP_002330428.1 CDS nrdF NC_011601.1 3031232 3032191 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3031232..3032191 Escherichia coli O127:H6 str. E2348/69 7065412 YP_002330429.1 CDS proV NC_011601.1 3032548 3033750 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3032548..3033750 Escherichia coli O127:H6 str. E2348/69 7065413 YP_002330430.1 CDS proW NC_011601.1 3033743 3034807 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3033743..3034807 Escherichia coli O127:H6 str. E2348/69 7061305 YP_002330431.1 CDS proX NC_011601.1 3034865 3035857 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3034865..3035857 Escherichia coli O127:H6 str. E2348/69 7061306 YP_002330432.1 CDS ygaY NC_011601.1 3036306 3037490 D transporter 3036306..3037490 Escherichia coli O127:H6 str. E2348/69 7061307 YP_002330433.1 CDS ygaZ NC_011601.1 3037614 3038351 D transporter 3037614..3038351 Escherichia coli O127:H6 str. E2348/69 7064417 YP_002330434.1 CDS ygaH NC_011601.1 3038341 3038676 D hypothetical protein 3038341..3038676 Escherichia coli O127:H6 str. E2348/69 7064418 YP_002330435.1 CDS mprA NC_011601.1 3038767 3039297 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3038767..3039297 Escherichia coli O127:H6 str. E2348/69 7064411 YP_002330436.1 CDS emrA NC_011601.1 3039424 3040596 D multidrug efflux system 3039424..3040596 Escherichia coli O127:H6 str. E2348/69 7063827 YP_002330437.1 CDS emrB NC_011601.1 3040613 3042151 D multidrug efflux system protein 3040613..3042151 Escherichia coli O127:H6 str. E2348/69 7063844 YP_002330438.1 CDS E2348C_2951 NC_011601.1 3042409 3043116 D hypothetical protein 3042409..3043116 Escherichia coli O127:H6 str. E2348/69 7063845 YP_002330439.1 CDS E2348C_2952 NC_011601.1 3043113 3044225 D hypothetical protein 3043113..3044225 Escherichia coli O127:H6 str. E2348/69 7062566 YP_002330440.1 CDS E2348C_2953 NC_011601.1 3044413 3045786 D transposase of ISEc13 3044413..3045786 Escherichia coli O127:H6 str. E2348/69 7061107 YP_002330441.1 CDS E2348C_2954 NC_011601.1 3045894 3046352 R transposase of IS200C complement(3045894..3046352) Escherichia coli O127:H6 str. E2348/69 7061108 YP_002330442.1 CDS luxS NC_011601.1 3046545 3047060 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(3046545..3047060) Escherichia coli O127:H6 str. E2348/69 7062567 YP_002330443.1 CDS gshA NC_011601.1 3047210 3048766 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(3047210..3048766) Escherichia coli O127:H6 str. E2348/69 7063785 YP_002330444.1 CDS yqaA NC_011601.1 3048839 3049267 R hypothetical protein complement(3048839..3049267) Escherichia coli O127:H6 str. E2348/69 7064250 YP_002330445.1 CDS yqaB NC_011601.1 3049264 3049830 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(3049264..3049830) Escherichia coli O127:H6 str. E2348/69 7061253 YP_002330446.1 CDS csrA NC_011601.1 3050886 3051071 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(3050886..3051071) Escherichia coli O127:H6 str. E2348/69 7065244 YP_002330447.1 CDS alaS NC_011601.1 3051306 3053936 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(3051306..3053936) Escherichia coli O127:H6 str. E2348/69 7062866 YP_002330448.1 CDS recX NC_011601.1 3054065 3054565 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(3054065..3054565) Escherichia coli O127:H6 str. E2348/69 7062429 YP_002330449.1 CDS recA NC_011601.1 3054634 3055695 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(3054634..3055695) Escherichia coli O127:H6 str. E2348/69 7063986 YP_002330450.1 CDS ygaD NC_011601.1 3055775 3056272 R competence damage-inducible protein A complement(3055775..3056272) Escherichia coli O127:H6 str. E2348/69 7063975 YP_002330451.1 CDS mltB NC_011601.1 3056417 3057502 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(3056417..3057502) Escherichia coli O127:H6 str. E2348/69 7064410 YP_002330452.1 CDS gutQ NC_011601.1 3057756 3058721 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3057756..3058721 Escherichia coli O127:H6 str. E2348/69 7063795 YP_002330453.1 CDS norR NC_011601.1 3058718 3060232 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(3058718..3060232) Escherichia coli O127:H6 str. E2348/69 7064277 YP_002330454.1 CDS norV NC_011601.1 3060419 3061858 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3060419..3061858 Escherichia coli O127:H6 str. E2348/69 7065406 YP_002330455.1 CDS norW NC_011601.1 3061855 3062988 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3061855..3062988 Escherichia coli O127:H6 str. E2348/69 7065407 YP_002330456.1 CDS E2348C_2969 NC_011601.1 3063173 3063694 D transposase Orf1 of IS1397 3063173..3063694 Escherichia coli O127:H6 str. E2348/69 7061109 YP_002330457.1 CDS E2348C_2972 NC_011601.1 3064460 3065536 R transposase of ISEc21 complement(3064460..3065536) Escherichia coli O127:H6 str. E2348/69 7061111 YP_002330458.1 CDS E2348C_2974 NC_011601.1 3066375 3066686 R transposase Orf1 of IS3 family IS element complement(3066375..3066686) Escherichia coli O127:H6 str. E2348/69 7062569 YP_002330459.1 CDS hydN NC_011601.1 3069541 3070068 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(3069541..3070068) Escherichia coli O127:H6 str. E2348/69 7063510 YP_002330460.1 CDS E2348C_2978 NC_011601.1 3070602 3071975 D transposase of ISEc13 3070602..3071975 Escherichia coli O127:H6 str. E2348/69 7061114 YP_002330461.1 CDS E2348C_2979 NC_011601.1 3072113 3072571 D transposase of IS200C 3072113..3072571 Escherichia coli O127:H6 str. E2348/69 7061115 YP_002330462.1 CDS E2348C_2980 NC_011601.1 3072723 3073151 D hypothetical protein 3072723..3073151 Escherichia coli O127:H6 str. E2348/69 7062571 YP_002330463.1 CDS E2348C_2981 NC_011601.1 3073243 3073662 R hypothetical protein complement(3073243..3073662) Escherichia coli O127:H6 str. E2348/69 7062572 YP_002330464.1 CDS hycI NC_011601.1 3074137 3074607 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3074137..3074607) Escherichia coli O127:H6 str. E2348/69 7062573 YP_002330465.1 CDS hycH NC_011601.1 3074600 3075010 R HycH protein required for maturation of hydrogenase 3 complement(3074600..3075010) Escherichia coli O127:H6 str. E2348/69 7062217 YP_002330466.1 CDS hycG NC_011601.1 3075007 3075774 R hydrogenase 3 and formate hydrogenase complex, HycG subunit complement(3075007..3075774) Escherichia coli O127:H6 str. E2348/69 7062216 YP_002330467.1 CDS hycF NC_011601.1 3075774 3076316 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3075774..3076316) Escherichia coli O127:H6 str. E2348/69 7062215 YP_002330468.1 CDS hycE NC_011601.1 3076326 3078035 R hydrogenase 3, large subunit complement(3076326..3078035) Escherichia coli O127:H6 str. E2348/69 7062214 YP_002330469.1 CDS hycD NC_011601.1 3078053 3078976 R hydrogenase 3, membrane subunit complement(3078053..3078976) Escherichia coli O127:H6 str. E2348/69 7062213 YP_002330470.1 CDS hycC NC_011601.1 3078979 3080805 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3078979..3080805) Escherichia coli O127:H6 str. E2348/69 7062212 YP_002330471.1 CDS hycB NC_011601.1 3080802 3081413 R hydrogenase 3, Fe-S subunit complement(3080802..3081413) Escherichia coli O127:H6 str. E2348/69 7062211 YP_002330472.1 CDS hycA NC_011601.1 3081538 3081999 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3081538..3081999) Escherichia coli O127:H6 str. E2348/69 7062210 YP_002330473.1 CDS hypA NC_011601.1 3082211 3082561 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3082211..3082561 Escherichia coli O127:H6 str. E2348/69 7062209 YP_002330474.1 CDS hypB NC_011601.1 3082565 3083437 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3082565..3083437 Escherichia coli O127:H6 str. E2348/69 7063504 YP_002330475.1 CDS hypC NC_011601.1 3083428 3083700 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3083428..3083700 Escherichia coli O127:H6 str. E2348/69 7063506 YP_002330476.1 CDS hypD NC_011601.1 3083700 3084821 D HypD protein required for maturation of hydrogenases 3083700..3084821 Escherichia coli O127:H6 str. E2348/69 7063507 YP_002330477.1 CDS hypE NC_011601.1 3084860 3085828 D carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein HypE 3084860..3085828 Escherichia coli O127:H6 str. E2348/69 7063508 YP_002330478.1 CDS fhlA NC_011601.1 3085902 3087980 D DNA-binding transcriptional activator 3085902..3087980 Escherichia coli O127:H6 str. E2348/69 7063509 YP_002330479.1 CDS E2348C_2997 NC_011601.1 3087986 3088453 D molybdenum-pterin-binding protein 3087986..3088453 Escherichia coli O127:H6 str. E2348/69 7062110 YP_002330480.1 CDS ygbA NC_011601.1 3088492 3088836 R hypothetical protein complement(3088492..3088836) Escherichia coli O127:H6 str. E2348/69 7062574 YP_002330481.1 CDS mutS NC_011601.1 3089121 3091682 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3089121..3091682 Escherichia coli O127:H6 str. E2348/69 7064419 YP_002330482.1 CDS pphB NC_011601.1 3091788 3092444 D serine/threonine-specific protein phosphatase 2 3091788..3092444 Escherichia coli O127:H6 str. E2348/69 7060900 YP_002330483.1 CDS ygbI NC_011601.1 3092495 3093292 R DNA-binding transcriptional regulator complement(3092495..3093292) Escherichia coli O127:H6 str. E2348/69 7061269 YP_002330484.1 CDS ygbJ NC_011601.1 3093458 3094366 D dehydrogenase, with NAD(P)-binding Rossmann-fold domain 3093458..3094366 Escherichia coli O127:H6 str. E2348/69 7064421 YP_002330485.1 CDS ygbK NC_011601.1 3094363 3095625 D hypothetical protein 3094363..3095625 Escherichia coli O127:H6 str. E2348/69 7064422 YP_002330486.1 CDS ygbL NC_011601.1 3095622 3096260 D aldolase 3095622..3096260 Escherichia coli O127:H6 str. E2348/69 7064423 YP_002330487.1 CDS ygbM NC_011601.1 3096265 3097041 D hypothetical protein 3096265..3097041 Escherichia coli O127:H6 str. E2348/69 7064424 YP_002330488.1 CDS ygbN NC_011601.1 3097130 3098494 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3097130..3098494 Escherichia coli O127:H6 str. E2348/69 7064425 YP_002330489.1 CDS E2348C_3007 NC_011601.1 3098533 3098769 R hypothetical protein complement(3098533..3098769) Escherichia coli O127:H6 str. E2348/69 7064426 YP_002330490.1 CDS E2348C_3008 NC_011601.1 3098780 3100207 R 4-hydroxybenzoate decarboxylase complement(3098780..3100207) Escherichia coli O127:H6 str. E2348/69 7062575 YP_002330491.1 CDS E2348C_3009 NC_011601.1 3100207 3100800 R phenylacrylic acid decarboxylase complement(3100207..3100800) Escherichia coli O127:H6 str. E2348/69 7062576 YP_002330492.1 CDS E2348C_3010 NC_011601.1 3100947 3101354 D transcriptional regulator (MarR-family) 3100947..3101354 Escherichia coli O127:H6 str. E2348/69 7062577 YP_002330493.1 CDS nlpD NC_011601.1 3102530 3103669 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3102530..3103669) Escherichia coli O127:H6 str. E2348/69 7061870 YP_002330494.1 CDS pcm NC_011601.1 3103809 3104435 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3103809..3104435) Escherichia coli O127:H6 str. E2348/69 7065403 YP_002330495.1 CDS surE NC_011601.1 3104429 3105190 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3104429..3105190) Escherichia coli O127:H6 str. E2348/69 7062916 YP_002330496.1 CDS truD NC_011601.1 3105171 3106220 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3105171..3106220) Escherichia coli O127:H6 str. E2348/69 7061745 YP_002330497.1 CDS ispF NC_011601.1 3106217 3106696 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3106217..3106696) Escherichia coli O127:H6 str. E2348/69 7062266 YP_002330498.1 CDS ispD NC_011601.1 3106696 3107406 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3106696..3107406) Escherichia coli O127:H6 str. E2348/69 7063555 YP_002330499.1 CDS ftsB NC_011601.1 3107425 3107736 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3107425..3107736) Escherichia coli O127:H6 str. E2348/69 7063553 YP_002330500.1 CDS ygbE NC_011601.1 3107929 3108252 R hypothetical protein complement(3107929..3108252) Escherichia coli O127:H6 str. E2348/69 7061582 YP_002330501.1 CDS cysC NC_011601.1 3108302 3108907 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3108302..3108907) Escherichia coli O127:H6 str. E2348/69 7064420 YP_002330502.1 CDS cysN NC_011601.1 3108907 3110334 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3108907..3110334) Escherichia coli O127:H6 str. E2348/69 7065195 YP_002330503.1 CDS cysD NC_011601.1 3110336 3111244 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3110336..3111244) Escherichia coli O127:H6 str. E2348/69 7065204 YP_002330504.1 CDS iap NC_011601.1 3111496 3112533 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3111496..3112533 Escherichia coli O127:H6 str. E2348/69 7065196 YP_002330505.1 CDS E2348C_3024 NC_011601.1 3112872 3114146 D transposase 3112872..3114146 Escherichia coli O127:H6 str. E2348/69 7063514 YP_002330506.1 CDS cysH NC_011601.1 3114175 3114909 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3114175..3114909) Escherichia coli O127:H6 str. E2348/69 7062579 YP_002330507.1 CDS cysI NC_011601.1 3114983 3116695 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3114983..3116695) Escherichia coli O127:H6 str. E2348/69 7065199 YP_002330508.1 CDS cysJ NC_011601.1 3116695 3118494 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3116695..3118494) Escherichia coli O127:H6 str. E2348/69 7065200 YP_002330509.1 CDS sscR NC_011601.1 3118810 3119175 D 6-pyruvoyl tetrahydrobiopterin synthase 3118810..3119175 Escherichia coli O127:H6 str. E2348/69 7065201 YP_002330510.1 CDS ygcN NC_011601.1 3119253 3120524 D oxidoreductase with FAD/NAD(P)-binding domain 3119253..3120524 Escherichia coli O127:H6 str. E2348/69 7062761 YP_002330511.1 CDS ygcO NC_011601.1 3120515 3120775 D (4Fe-4S)-binding protein 3120515..3120775 Escherichia coli O127:H6 str. E2348/69 7064431 YP_002330512.1 CDS ygcP NC_011601.1 3120792 3121367 D anti-terminator regulatory protein 3120792..3121367 Escherichia coli O127:H6 str. E2348/69 7064432 YP_002330513.1 CDS ygcQ NC_011601.1 3121515 3122375 R flavoprotein complement(3121515..3122375) Escherichia coli O127:H6 str. E2348/69 7064433 YP_002330514.1 CDS ygcR NC_011601.1 3122372 3123151 R flavoprotein complement(3122372..3123151) Escherichia coli O127:H6 str. E2348/69 7064434 YP_002330515.1 CDS ygcS NC_011601.1 3123129 3124466 R transporter complement(3123129..3124466) Escherichia coli O127:H6 str. E2348/69 7064435 YP_002330516.1 CDS ygcU NC_011601.1 3124560 3126014 R FAD containing dehydrogenase complement(3124560..3126014) Escherichia coli O127:H6 str. E2348/69 7064436 YP_002330517.1 CDS ygcW NC_011601.1 3126084 3126869 R deoxygluconate dehydrogenase complement(3126084..3126869) Escherichia coli O127:H6 str. E2348/69 7064437 YP_002330518.1 CDS yqcE NC_011601.1 3127187 3128464 D transporter 3127187..3128464 Escherichia coli O127:H6 str. E2348/69 7064438 YP_002330519.1 CDS ygcE NC_011601.1 3128491 3129969 D kinase 3128491..3129969 Escherichia coli O127:H6 str. E2348/69 7061257 YP_002330520.1 CDS scrK NC_011601.1 3130134 3131054 D phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 3130134..3131054 Escherichia coli O127:H6 str. E2348/69 7064428 YP_002330521.1 CDS scrY NC_011601.1 3131222 3132739 D sucrose porin 3131222..3132739 Escherichia coli O127:H6 str. E2348/69 7065341 YP_002330522.1 CDS scrA NC_011601.1 3132800 3134170 D PTS system, sucrose-specific IIBC component 3132800..3134170 Escherichia coli O127:H6 str. E2348/69 7065343 YP_002330523.1 CDS scrB NC_011601.1 3134170 3135579 D sucrose-6-phosphate hydrolase 3134170..3135579 Escherichia coli O127:H6 str. E2348/69 7065339 YP_002330524.1 CDS scrR NC_011601.1 3135605 3136612 D sucrose operon repressor 3135605..3136612 Escherichia coli O127:H6 str. E2348/69 7065340 YP_002330525.1 CDS ygcF NC_011601.1 3136697 3137368 R hypothetical protein complement(3136697..3137368) Escherichia coli O127:H6 str. E2348/69 7065342 YP_002330526.1 CDS ygcG NC_011601.1 3137662 3138534 D hypothetical protein 3137662..3138534 Escherichia coli O127:H6 str. E2348/69 7064429 YP_002330527.1 CDS eno NC_011601.1 3138594 3139892 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3138594..3139892) Escherichia coli O127:H6 str. E2348/69 7064430 YP_002330528.1 CDS pyrG NC_011601.1 3139980 3141617 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3139980..3141617) Escherichia coli O127:H6 str. E2348/69 7063851 YP_002330529.1 CDS mazG NC_011601.1 3141845 3142636 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase complement(3141845..3142636) Escherichia coli O127:H6 str. E2348/69 7063934 YP_002330530.1 CDS chpA NC_011601.1 3142708 3143043 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3142708..3143043) Escherichia coli O127:H6 str. E2348/69 7065295 YP_002330531.1 CDS chpR NC_011601.1 3143043 3143291 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(3143043..3143291) Escherichia coli O127:H6 str. E2348/69 7062786 YP_002330532.1 CDS relA NC_011601.1 3143369 3145603 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3143369..3145603) Escherichia coli O127:H6 str. E2348/69 7062788 YP_002330533.1 CDS rumA NC_011601.1 3145651 3146952 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3145651..3146952) Escherichia coli O127:H6 str. E2348/69 7063987 YP_002330534.1 CDS barA NC_011601.1 3147009 3149765 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3147009..3149765 Escherichia coli O127:H6 str. E2348/69 7064578 YP_002330535.1 CDS gudD NC_011601.1 3149996 3151336 R (D)-glucarate dehydratase 1 complement(3149996..3151336) Escherichia coli O127:H6 str. E2348/69 7062493 YP_002330536.1 CDS gudX NC_011601.1 3151357 3152697 R glucarate dehydratase complement(3151357..3152697) Escherichia coli O127:H6 str. E2348/69 7064274 YP_002330537.1 CDS gudP NC_011601.1 3152699 3154051 R D-glucarate transporter complement(3152699..3154051) Escherichia coli O127:H6 str. E2348/69 7064276 YP_002330538.1 CDS yqcA NC_011601.1 3154485 3154934 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3154485..3154934) Escherichia coli O127:H6 str. E2348/69 7064275 YP_002330539.1 CDS truC NC_011601.1 3154952 3155734 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3154952..3155734) Escherichia coli O127:H6 str. E2348/69 7061256 YP_002330540.1 CDS ygcC NC_011601.1 3155734 3156063 R hypothetical protein complement(3155734..3156063) Escherichia coli O127:H6 str. E2348/69 7062265 YP_002330541.1 CDS syd NC_011601.1 3156685 3157230 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3156685..3157230) Escherichia coli O127:H6 str. E2348/69 7065163 YP_002330542.1 CDS queF NC_011601.1 3157298 3158146 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3157298..3158146 Escherichia coli O127:H6 str. E2348/69 7061746 YP_002330543.1 CDS ygdH NC_011601.1 3158258 3159622 D hypothetical protein 3158258..3159622 Escherichia coli O127:H6 str. E2348/69 7063945 YP_002330544.1 CDS sdaC NC_011601.1 3160179 3161468 D serine transporter 3160179..3161468 Escherichia coli O127:H6 str. E2348/69 7064442 YP_002330545.1 CDS sdaB NC_011601.1 3161526 3162893 D L-serine deaminase II 3161526..3162893 Escherichia coli O127:H6 str. E2348/69 7065346 YP_002330546.1 CDS xni NC_011601.1 3162914 3163759 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3162914..3163759 Escherichia coli O127:H6 str. E2348/69 7065345 YP_002330547.1 CDS fucO NC_011601.1 3163814 3164965 R L-1,2-propanediol oxidoreductase complement(3163814..3164965) Escherichia coli O127:H6 str. E2348/69 7064865 YP_002330548.1 CDS fucA NC_011601.1 3164990 3165637 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3164990..3165637) Escherichia coli O127:H6 str. E2348/69 7061596 YP_002330549.1 CDS fucP NC_011601.1 3166184 3167500 D L-fucose transporter 3166184..3167500 Escherichia coli O127:H6 str. E2348/69 7061593 YP_002330550.1 CDS fucI NC_011601.1 3167533 3169308 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3167533..3169308 Escherichia coli O127:H6 str. E2348/69 7061597 YP_002330551.1 CDS fucK NC_011601.1 3169387 3170835 D L-fuculokinase 3169387..3170835 Escherichia coli O127:H6 str. E2348/69 7061594 YP_002330552.1 CDS fucU NC_011601.1 3170837 3171259 D L-fucose mutarotase 3170837..3171259 Escherichia coli O127:H6 str. E2348/69 7061595 YP_002330553.1 CDS fucR NC_011601.1 3171317 3172048 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3171317..3172048 Escherichia coli O127:H6 str. E2348/69 7061599 YP_002330554.1 CDS ygdE NC_011601.1 3172092 3173192 R RNA 2'-O-ribose methyltransferase complement(3172092..3173192) Escherichia coli O127:H6 str. E2348/69 7061598 YP_002330555.1 CDS ygdD NC_011601.1 3173185 3173580 R hypothetical protein complement(3173185..3173580) Escherichia coli O127:H6 str. E2348/69 7064441 YP_002330556.1 CDS gcvA NC_011601.1 3173599 3174516 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3173599..3174516) Escherichia coli O127:H6 str. E2348/69 7064440 YP_002330557.1 CDS ygdI NC_011601.1 3174867 3175094 R hypothetical protein complement(3174867..3175094) Escherichia coli O127:H6 str. E2348/69 7061642 YP_002330558.1 CDS csdA NC_011601.1 3175286 3176491 D cysteine sulfinate desulfinase 3175286..3176491 Escherichia coli O127:H6 str. E2348/69 7064443 YP_002330559.1 CDS ygdK NC_011601.1 3176491 3176934 D Fe-S metabolism protein 3176491..3176934 Escherichia coli O127:H6 str. E2348/69 7062849 YP_002330560.1 CDS ygdL NC_011601.1 3176985 3177791 R hypothetical protein complement(3176985..3177791) Escherichia coli O127:H6 str. E2348/69 7064444 YP_002330561.1 CDS mltA NC_011601.1 3177868 3178965 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3177868..3178965) Escherichia coli O127:H6 str. E2348/69 7063665 YP_002330562.1 CDS E2348C_3081 NC_011601.1 3179550 3180497 R dehydrogenase complement(3179550..3180497) Escherichia coli O127:H6 str. E2348/69 7063772 YP_002330563.1 CDS E2348C_3082 NC_011601.1 3180569 3181165 R phosphosugar isomerase complement(3180569..3181165) Escherichia coli O127:H6 str. E2348/69 7062580 YP_002330564.1 CDS E2348C_3083 NC_011601.1 3181168 3182343 R aminotransferase complement(3181168..3182343) Escherichia coli O127:H6 str. E2348/69 7062581 YP_002330565.1 CDS E2348C_3085 NC_011601.1 3183955 3184836 R antiterminator complement(3183955..3184836) Escherichia coli O127:H6 str. E2348/69 7062583 YP_002330566.1 CDS amiC NC_011601.1 3185037 3186290 R N-acetylmuramoyl-L-alanine amidase complement(3185037..3186290) Escherichia coli O127:H6 str. E2348/69 7062584 YP_002330567.1 CDS argA NC_011601.1 3186522 3187853 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3186522..3187853 Escherichia coli O127:H6 str. E2348/69 7062454 YP_002330568.1 CDS recD NC_011601.1 3187935 3189761 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3187935..3189761) Escherichia coli O127:H6 str. E2348/69 7061365 YP_002330569.1 CDS recB NC_011601.1 3189761 3193303 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3189761..3193303) Escherichia coli O127:H6 str. E2348/69 7063978 YP_002330570.1 CDS ptr NC_011601.1 3193296 3196184 R protease III complement(3193296..3196184) Escherichia coli O127:H6 str. E2348/69 7063976 YP_002330571.1 CDS recC NC_011601.1 3196360 3199728 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3196360..3199728) Escherichia coli O127:H6 str. E2348/69 7061335 YP_002330572.1 CDS ppdC NC_011601.1 3199741 3200064 R hypothetical protein complement(3199741..3200064) Escherichia coli O127:H6 str. E2348/69 7063977 YP_002330573.1 CDS ygdB NC_011601.1 3200049 3200456 R hypothetical protein complement(3200049..3200456) Escherichia coli O127:H6 str. E2348/69 7061266 YP_002330574.1 CDS ppdB NC_011601.1 3200453 3201016 R hypothetical protein complement(3200453..3201016) Escherichia coli O127:H6 str. E2348/69 7064439 YP_002330575.1 CDS ppdA NC_011601.1 3201007 3201477 R hypothetical protein complement(3201007..3201477) Escherichia coli O127:H6 str. E2348/69 7061265 YP_002330576.1 CDS thyA NC_011601.1 3201662 3202456 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3201662..3202456) Escherichia coli O127:H6 str. E2348/69 7061264 YP_002330577.1 CDS lgt NC_011601.1 3202463 3203338 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3202463..3203338) Escherichia coli O127:H6 str. E2348/69 7061802 YP_002330578.1 CDS ptsP NC_011601.1 3203489 3205735 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3203489..3205735) Escherichia coli O127:H6 str. E2348/69 7061538 YP_002330579.1 CDS nudH NC_011601.1 3205748 3206278 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3205748..3206278) Escherichia coli O127:H6 str. E2348/69 7063910 YP_002330580.1 CDS ygdT NC_011601.1 3206631 3206777 R hypothetical protein complement(3206631..3206777) Escherichia coli O127:H6 str. E2348/69 7065432 YP_002330581.1 CDS mutH NC_011601.1 3206963 3207652 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3206963..3207652 Escherichia coli O127:H6 str. E2348/69 7063668 YP_002330582.1 CDS ygdQ NC_011601.1 3207721 3208434 D hypothetical protein 3207721..3208434 Escherichia coli O127:H6 str. E2348/69 7060897 YP_002330583.1 CDS ygdR NC_011601.1 3208572 3208790 D hypothetical protein 3208572..3208790 Escherichia coli O127:H6 str. E2348/69 7063666 YP_002330584.1 CDS tas NC_011601.1 3208898 3209938 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo/keto reductase 3208898..3209938 Escherichia coli O127:H6 str. E2348/69 7063667 YP_002330585.1 CDS lplT NC_011601.1 3209970 3211163 R lysophospholipid transporter LplT complement(3209970..3211163) Escherichia coli O127:H6 str. E2348/69 7061754 YP_002330586.1 CDS aas NC_011601.1 3211156 3213315 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3211156..3213315) Escherichia coli O127:H6 str. E2348/69 7061568 YP_002330587.1 CDS galR NC_011601.1 3213901 3214932 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3213901..3214932 Escherichia coli O127:H6 str. E2348/69 7062882 YP_002330588.1 CDS lysA NC_011601.1 3214939 3216201 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3214939..3216201) Escherichia coli O127:H6 str. E2348/69 7061621 YP_002330589.1 CDS lysR NC_011601.1 3216323 3217258 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3216323..3217258 Escherichia coli O127:H6 str. E2348/69 7065250 YP_002330590.1 CDS ygeA NC_011601.1 3217245 3217937 R racemase complement(3217245..3217937) Escherichia coli O127:H6 str. E2348/69 7065255 YP_002330591.1 CDS araE NC_011601.1 3218066 3219484 R arabinose transporter complement(3218066..3219484) Escherichia coli O127:H6 str. E2348/69 7063344 YP_002330592.1 CDS E2348C_3112 NC_011601.1 3219784 3221157 R transposase of ISEc13 complement(3219784..3221157) Escherichia coli O127:H6 str. E2348/69 7061116 YP_002330593.1 CDS kduD NC_011601.1 3221359 3222120 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3221359..3222120) Escherichia coli O127:H6 str. E2348/69 7062585 YP_002330594.1 CDS kduI NC_011601.1 3222150 3222986 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3222150..3222986) Escherichia coli O127:H6 str. E2348/69 7063582 YP_002330595.1 CDS yqeF NC_011601.1 3223273 3224454 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3223273..3224454) Escherichia coli O127:H6 str. E2348/69 7063583 YP_002330596.1 CDS yqeG NC_011601.1 3224709 3225938 D transporter 3224709..3225938 Escherichia coli O127:H6 str. E2348/69 7063185 YP_002330597.1 CDS ygeR NC_011601.1 3226406 3227161 R tetratricopeptide repeat transcriptional regulator complement(3226406..3227161) Escherichia coli O127:H6 str. E2348/69 7061724 YP_002330598.1 CDS xdhA NC_011601.1 3227575 3229872 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3227575..3229872 Escherichia coli O127:H6 str. E2348/69 7063345 YP_002330599.1 CDS xdhB NC_011601.1 3229883 3230761 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3229883..3230761 Escherichia coli O127:H6 str. E2348/69 7064859 YP_002330600.1 CDS xdhC NC_011601.1 3230758 3231237 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3230758..3231237 Escherichia coli O127:H6 str. E2348/69 7064860 YP_002330601.1 CDS ygeV NC_011601.1 3231277 3233055 R DNA-binding transcriptional regulator complement(3231277..3233055) Escherichia coli O127:H6 str. E2348/69 7064861 YP_002330602.1 CDS ygeW NC_011601.1 3233534 3234721 D aspartate/ornithine carbamoyltransferase 3233534..3234721 Escherichia coli O127:H6 str. E2348/69 7063346 YP_002330603.1 CDS ygeX NC_011601.1 3234779 3235975 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3234779..3235975 Escherichia coli O127:H6 str. E2348/69 7063347 YP_002330604.1 CDS ygeY NC_011601.1 3236033 3237244 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3236033..3237244 Escherichia coli O127:H6 str. E2348/69 7063348 YP_002330605.1 CDS hyuA NC_011601.1 3237297 3238682 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3237297..3238682 Escherichia coli O127:H6 str. E2348/69 7063349 YP_002330606.1 CDS yqeA NC_011601.1 3238730 3239662 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3238730..3239662 Escherichia coli O127:H6 str. E2348/69 7063511 YP_002330607.1 CDS yqeB NC_011601.1 3239703 3241328 R hypothetical protein complement(3239703..3241328) Escherichia coli O127:H6 str. E2348/69 7061258 YP_002330608.1 CDS yqeC NC_011601.1 3241376 3242146 R hypothetical protein complement(3241376..3242146) Escherichia coli O127:H6 str. E2348/69 7061259 YP_002330609.1 CDS ygfJ NC_011601.1 3242250 3242828 D hypothetical protein 3242250..3242828 Escherichia coli O127:H6 str. E2348/69 7063184 YP_002330610.1 CDS E2348C_3131 NC_011601.1 3243846 3245219 R transposase of ISEc13 complement(3243846..3245219) Escherichia coli O127:H6 str. E2348/69 7061117 YP_002330611.1 CDS ssnA NC_011601.1 3247810 3249138 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3247810..3249138 Escherichia coli O127:H6 str. E2348/69 7062586 YP_002330612.1 CDS ygfM NC_011601.1 3249189 3249968 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3249189..3249968 Escherichia coli O127:H6 str. E2348/69 7062764 YP_002330613.1 CDS ygfO NC_011601.1 3253000 3254400 D transporter 3253000..3254400 Escherichia coli O127:H6 str. E2348/69 7064862 YP_002330614.1 CDS guaD NC_011601.1 3254418 3255734 D Catalyzes the deamination of guanine; guanine deaminase 3254418..3255734 Escherichia coli O127:H6 str. E2348/69 7063355 YP_002330615.1 CDS ygfQ NC_011601.1 3255770 3257137 D transporter 3255770..3257137 Escherichia coli O127:H6 str. E2348/69 7064273 YP_002330616.1 CDS ygfS NC_011601.1 3257173 3257661 R oxidoreductase, 4Fe-4S ferredoxin-type subunit complement(3257173..3257661) Escherichia coli O127:H6 str. E2348/69 7063356 YP_002330617.1 CDS ygfT NC_011601.1 3257661 3259580 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3257661..3259580) Escherichia coli O127:H6 str. E2348/69 7063357 YP_002330618.1 CDS ygfU NC_011601.1 3260016 3261464 D transporter 3260016..3261464 Escherichia coli O127:H6 str. E2348/69 7063358 YP_002330619.1 CDS E2348C_3141 NC_011601.1 3261466 3261591 D hypothetical protein 3261466..3261591 Escherichia coli O127:H6 str. E2348/69 7063359 YP_002330620.1 CDS idi NC_011601.1 3261713 3262261 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3261713..3262261 Escherichia coli O127:H6 str. E2348/69 7062587 YP_002330621.1 CDS lysS NC_011601.1 3262304 3263821 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3262304..3263821) Escherichia coli O127:H6 str. E2348/69 7063519 YP_002330622.1 CDS prfB NC_011601.1 3263831 3264929 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(join(3263831..3264853,3264855..3264929)) Escherichia coli O127:H6 str. E2348/69 7065256 YP_002330623.1 CDS recJ NC_011601.1 3265020 3266753 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3265020..3266753) Escherichia coli O127:H6 str. E2348/69 7061285 YP_002330624.1 CDS dsbC NC_011601.1 3266759 3267469 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3266759..3267469) Escherichia coli O127:H6 str. E2348/69 7063981 YP_002330625.1 CDS xerD NC_011601.1 3267494 3268390 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3267494..3268390) Escherichia coli O127:H6 str. E2348/69 7065064 YP_002330626.1 CDS fldB NC_011601.1 3268502 3269023 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3268502..3269023 Escherichia coli O127:H6 str. E2348/69 7064864 YP_002330627.1 CDS ygfX NC_011601.1 3269063 3269470 R hypothetical protein complement(3269063..3269470) Escherichia coli O127:H6 str. E2348/69 7062137 YP_002330628.1 CDS ygfY NC_011601.1 3269451 3269717 R hypothetical protein complement(3269451..3269717) Escherichia coli O127:H6 str. E2348/69 7063360 YP_002330629.1 CDS ygfZ NC_011601.1 3269960 3270940 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3269960..3270940 Escherichia coli O127:H6 str. E2348/69 7063361 YP_002330630.1 CDS yqfA NC_011601.1 3271017 3271676 R oxidoreductase, inner membrane subunit complement(3271017..3271676) Escherichia coli O127:H6 str. E2348/69 7063362 YP_002330631.1 CDS yqfB NC_011601.1 3271840 3272151 R hypothetical protein complement(3271840..3272151) Escherichia coli O127:H6 str. E2348/69 7063187 YP_002330632.1 CDS bglA NC_011601.1 3272190 3273629 D 6-phospho-beta-glucosidase 3272190..3273629 Escherichia coli O127:H6 str. E2348/69 7063188 YP_002330633.1 CDS gcvP NC_011601.1 3273795 3276668 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3273795..3276668) Escherichia coli O127:H6 str. E2348/69 7062512 YP_002330634.1 CDS gcvH NC_011601.1 3276787 3277176 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3276787..3277176) Escherichia coli O127:H6 str. E2348/69 7061644 YP_002330635.1 CDS gcvT NC_011601.1 3277200 3278294 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3277200..3278294) Escherichia coli O127:H6 str. E2348/69 7061643 YP_002330636.1 CDS visC NC_011601.1 3278742 3279944 R hypothetical protein complement(3278742..3279944) Escherichia coli O127:H6 str. E2348/69 7061646 YP_002330637.1 CDS ubiH NC_011601.1 3279967 3281145 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3279967..3281145) Escherichia coli O127:H6 str. E2348/69 7062361 YP_002330638.1 CDS pepP NC_011601.1 3281142 3282467 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3281142..3282467) Escherichia coli O127:H6 str. E2348/69 7062297 YP_002330639.1 CDS ygfB NC_011601.1 3282493 3283071 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3282493..3283071) Escherichia coli O127:H6 str. E2348/69 7060703 YP_002330640.1 CDS zapA NC_011601.1 3283239 3283568 D Z-ring-associated protein 3283239..3283568 Escherichia coli O127:H6 str. E2348/69 7063351 YP_002330641.1 CDS ygfA NC_011601.1 3283814 3284416 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3283814..3284416 Escherichia coli O127:H6 str. E2348/69 7062768 YP_002330642.1 CDS serA NC_011601.1 3284805 3286037 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3284805..3286037) Escherichia coli O127:H6 str. E2348/69 7064602 YP_002330643.1 CDS rpiA NC_011601.1 3286293 3286952 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3286293..3286952) Escherichia coli O127:H6 str. E2348/69 7065366 YP_002330644.1 CDS argP NC_011601.1 3287651 3288544 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3287651..3288544 Escherichia coli O127:H6 str. E2348/69 7061827 YP_002330645.1 CDS ygfI NC_011601.1 3289685 3290656 R DNA-binding transcriptional regulator complement(3289685..3290656) Escherichia coli O127:H6 str. E2348/69 7065338 YP_002330646.1 CDS yggE NC_011601.1 3290814 3291554 R hypothetical protein complement(3290814..3291554) Escherichia coli O127:H6 str. E2348/69 7063352 YP_002330647.1 CDS argO NC_011601.1 3291647 3292282 R Involved in the export of arginine; arginine exporter protein complement(3291647..3292282) Escherichia coli O127:H6 str. E2348/69 7063365 YP_002330648.1 CDS mscS NC_011601.1 3292421 3293281 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3292421..3293281) Escherichia coli O127:H6 str. E2348/69 7061373 YP_002330649.1 CDS fbaA NC_011601.1 3293472 3294551 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3293472..3294551) Escherichia coli O127:H6 str. E2348/69 7060873 YP_002330650.1 CDS pgk NC_011601.1 3294765 3295928 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3294765..3295928) Escherichia coli O127:H6 str. E2348/69 7062081 YP_002330651.1 CDS epd NC_011601.1 3295978 3296997 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3295978..3296997) Escherichia coli O127:H6 str. E2348/69 7060714 YP_002330652.1 CDS E2348C_3175 NC_011601.1 3297369 3297800 D DNA-binding protein 3297369..3297800 Escherichia coli O127:H6 str. E2348/69 7063862 YP_002330653.1 CDS E2348C_3176 NC_011601.1 3297823 3298401 D transporter 3297823..3298401 Escherichia coli O127:H6 str. E2348/69 7062588 YP_002330654.1 CDS E2348C_3177 NC_011601.1 3298402 3299109 D lipoprotein 3298402..3299109 Escherichia coli O127:H6 str. E2348/69 7062589 YP_002330655.1 CDS E2348C_3178 NC_011601.1 3299097 3299774 D ABC transporter ATP-binding protein 3299097..3299774 Escherichia coli O127:H6 str. E2348/69 7062590 YP_002330656.1 CDS frcK NC_011601.1 3300417 3301130 R fructose transport system kinase complement(3300417..3301130) Escherichia coli O127:H6 str. E2348/69 7062592 YP_002330657.1 CDS yggD NC_011601.1 3301127 3301636 R DNA-binding transcriptional regulator complement(3301127..3301636) Escherichia coli O127:H6 str. E2348/69 7063363 YP_002330658.1 CDS yggF NC_011601.1 3301658 3302623 R fructose-1,6-bisphosphatase II-like protein complement(3301658..3302623) Escherichia coli O127:H6 str. E2348/69 7063364 YP_002330659.1 CDS yggP NC_011601.1 3302620 3303897 R dehydrogenase complement(3302620..3303897) Escherichia coli O127:H6 str. E2348/69 7063366 YP_002330660.1 CDS cmtA NC_011601.1 3303912 3305300 R fused mannitol-specific PTS enzymes: IIB component/IIC component complement(3303912..3305300) Escherichia coli O127:H6 str. E2348/69 7063372 YP_002330661.1 CDS cmtB NC_011601.1 3305328 3305771 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3305328..3305771) Escherichia coli O127:H6 str. E2348/69 7062818 YP_002330662.1 CDS E2348C_3186 NC_011601.1 3306148 3307056 D HflC-like, SPFC domain-containing protein 3306148..3307056 Escherichia coli O127:H6 str. E2348/69 7062819 YP_002330663.1 CDS tktA NC_011601.1 3307276 3309267 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3307276..3309267) Escherichia coli O127:H6 str. E2348/69 7062593 YP_002330664.1 CDS yggG NC_011601.1 3309545 3310303 D peptidase 3309545..3310303 Escherichia coli O127:H6 str. E2348/69 7061806 YP_002330665.1 CDS speB NC_011601.1 3310507 3311427 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3310507..3311427) Escherichia coli O127:H6 str. E2348/69 7063367 YP_002330666.1 CDS E2348C_3190 NC_011601.1 3311563 3312294 R hypothetical protein complement(3311563..3312294) Escherichia coli O127:H6 str. E2348/69 7062741 YP_002330667.1 CDS speA NC_011601.1 3312440 3314416 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3312440..3314416) Escherichia coli O127:H6 str. E2348/69 7062594 YP_002330668.1 CDS yqgB NC_011601.1 3314425 3314556 R hypothetical protein complement(3314425..3314556) Escherichia coli O127:H6 str. E2348/69 7062740 YP_002330669.1 CDS yqgC NC_011601.1 3314692 3314907 D hypothetical protein 3314692..3314907 Escherichia coli O127:H6 str. E2348/69 7063190 YP_002330670.1 CDS yqgD NC_011601.1 3314904 3315155 R hypothetical protein complement(3314904..3315155) Escherichia coli O127:H6 str. E2348/69 7063191 YP_002330671.1 CDS metK NC_011601.1 3315211 3316365 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3315211..3316365 Escherichia coli O127:H6 str. E2348/69 7063192 YP_002330672.1 CDS galP NC_011601.1 3316801 3318195 D D-galactose transporter 3316801..3318195 Escherichia coli O127:H6 str. E2348/69 7063765 YP_002330673.1 CDS yggI NC_011601.1 3318272 3318769 D hypothetical protein 3318272..3318769 Escherichia coli O127:H6 str. E2348/69 7061620 YP_002330674.1 CDS endA NC_011601.1 3318864 3319571 D DNA-specific endonuclease I 3318864..3319571 Escherichia coli O127:H6 str. E2348/69 7063368 YP_002330675.1 CDS rsmE NC_011601.1 3319650 3320381 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3319650..3320381 Escherichia coli O127:H6 str. E2348/69 7063850 YP_002330676.1 CDS gshB NC_011601.1 3320394 3321344 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3320394..3321344 Escherichia coli O127:H6 str. E2348/69 7064558 YP_002330677.1 CDS yqgE NC_011601.1 3321453 3322016 D hypothetical protein 3321453..3322016 Escherichia coli O127:H6 str. E2348/69 7064251 YP_002330678.1 CDS yqgF NC_011601.1 3322016 3322432 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3322016..3322432 Escherichia coli O127:H6 str. E2348/69 7063193 YP_002330679.1 CDS yggR NC_011601.1 3322439 3323419 R transporter complement(3322439..3323419) Escherichia coli O127:H6 str. E2348/69 7063194 YP_002330680.1 CDS yggS NC_011601.1 3323437 3324141 D hypothetical protein 3323437..3324141 Escherichia coli O127:H6 str. E2348/69 7063373 YP_002330681.1 CDS yggT NC_011601.1 3324159 3324725 D hypothetical protein 3324159..3324725 Escherichia coli O127:H6 str. E2348/69 7063374 YP_002330682.1 CDS yggU NC_011601.1 3324722 3325012 D hypothetical protein 3324722..3325012 Escherichia coli O127:H6 str. E2348/69 7063375 YP_002330683.1 CDS rdgB NC_011601.1 3325020 3325613 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3325020..3325613 Escherichia coli O127:H6 str. E2348/69 7063376 YP_002330684.1 CDS rdgW NC_011601.1 3325606 3326742 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3325606..3326742 Escherichia coli O127:H6 str. E2348/69 7063968 YP_002330685.1 CDS yggM NC_011601.1 3326807 3327814 R hypothetical protein complement(3326807..3327814) Escherichia coli O127:H6 str. E2348/69 7063970 YP_002330686.1 CDS ansB NC_011601.1 3327931 3328977 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3327931..3328977) Escherichia coli O127:H6 str. E2348/69 7063370 YP_002330687.1 CDS yggN NC_011601.1 3329153 3329872 R hypothetical protein complement(3329153..3329872) Escherichia coli O127:H6 str. E2348/69 7061345 YP_002330688.1 CDS yggL NC_011601.1 3330056 3330382 R hypothetical protein complement(3330056..3330382) Escherichia coli O127:H6 str. E2348/69 7063371 YP_002330689.1 CDS trmB NC_011601.1 3330382 3331101 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3330382..3331101) Escherichia coli O127:H6 str. E2348/69 7063369 YP_002330690.1 CDS mutY NC_011601.1 3331262 3332314 D adenine DNA glycosylase 3331262..3332314 Escherichia coli O127:H6 str. E2348/69 7062244 YP_002330691.1 CDS yggX NC_011601.1 3332342 3332617 D hypothetical protein 3332342..3332617 Escherichia coli O127:H6 str. E2348/69 7060902 YP_002330692.1 CDS mltC NC_011601.1 3332682 3333761 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3332682..3333761 Escherichia coli O127:H6 str. E2348/69 7063377 YP_002330693.1 CDS nupG NC_011601.1 3333963 3335219 D nucleoside transporter 3333963..3335219 Escherichia coli O127:H6 str. E2348/69 7063796 YP_002330694.1 CDS speC NC_011601.1 3335268 3337403 R ornithine decarboxylase complement(3335268..3337403) Escherichia coli O127:H6 str. E2348/69 7062787 YP_002330695.1 CDS yqgA NC_011601.1 3337802 3338509 D hypothetical protein 3337802..3338509 Escherichia coli O127:H6 str. E2348/69 7062742 YP_002330696.1 CDS E2348C_3220 NC_011601.1 3338888 3340153 D integrase 3338888..3340153 Escherichia coli O127:H6 str. E2348/69 7064959 YP_002330697.1 CDS E2348C_3222 NC_011601.1 3341144 3341818 D transposase Orf1 of IS683 3341144..3341818 Escherichia coli O127:H6 str. E2348/69 7061119 YP_002330698.1 CDS E2348C_3223 NC_011601.1 3341815 3342162 D transposase Orf2 of IS683 3341815..3342162 Escherichia coli O127:H6 str. E2348/69 7062595 YP_002330699.1 CDS E2348C_3226 NC_011601.1 3344484 3345032 R PagC-like membrane protein complement(3344484..3345032) Escherichia coli O127:H6 str. E2348/69 7062598 YP_002330700.1 CDS E2348C_3227 NC_011601.1 3345140 3345334 R hypothetical protein complement(3345140..3345334) Escherichia coli O127:H6 str. E2348/69 7062599 YP_002330701.1 CDS E2348C_3229 NC_011601.1 3347579 3347812 D hypothetical protein 3347579..3347812 Escherichia coli O127:H6 str. E2348/69 7062600 YP_002330702.1 CDS E2348C_3230 NC_011601.1 3348020 3349669 D T3SS secreted effector EspL-like protein 3348020..3349669 Escherichia coli O127:H6 str. E2348/69 7062601 YP_002330703.1 CDS E2348C_3231 NC_011601.1 3350278 3351267 D T3SS secreted effector NleB-like protein 3350278..3351267 Escherichia coli O127:H6 str. E2348/69 7061121 YP_002330704.1 CDS E2348C_3232 NC_011601.1 3351316 3351990 D T3SS secreted effector NleE-like protein 3351316..3351990 Escherichia coli O127:H6 str. E2348/69 7062602 YP_002330705.1 CDS E2348C_3234 NC_011601.1 3353864 3363535 D Efa1/LifA protein 3353864..3363535 Escherichia coli O127:H6 str. E2348/69 7062603 YP_002330706.1 CDS E2348C_3236 NC_011601.1 3364189 3364614 D transposase Orf1 of IS682 3364189..3364614 Escherichia coli O127:H6 str. E2348/69 7061124 YP_002330707.1 CDS E2348C_3237 NC_011601.1 3364611 3364961 D transposase Orf2 of IS682 3364611..3364961 Escherichia coli O127:H6 str. E2348/69 7062604 YP_002330708.1 CDS E2348C_3238 NC_011601.1 3365174 3366577 D transposase Orf3 of IS682 3365174..3366577 Escherichia coli O127:H6 str. E2348/69 7062605 YP_002330709.1 CDS E2348C_3239 NC_011601.1 3366913 3367959 D transposase 3366913..3367959 Escherichia coli O127:H6 str. E2348/69 7062606 YP_002330710.1 CDS gspM NC_011601.1 3368164 3368715 R general secretion pathway protein YghD complement(3368164..3368715) Escherichia coli O127:H6 str. E2348/69 7062607 YP_002330711.1 CDS gspL NC_011601.1 3368717 3369886 R similar to general secretory pathway protein L; GspL-like protein complement(3368717..3369886) Escherichia coli O127:H6 str. E2348/69 7064268 YP_002330712.1 CDS gspK NC_011601.1 3369892 3370869 R type II secretion protein complement(3369892..3370869) Escherichia coli O127:H6 str. E2348/69 7064267 YP_002330713.1 CDS gspJ NC_011601.1 3370866 3371471 R type II secretion protein complement(3370866..3371471) Escherichia coli O127:H6 str. E2348/69 7064266 YP_002330714.1 CDS gspI NC_011601.1 3371468 3371839 R type II secretion protein complement(3371468..3371839) Escherichia coli O127:H6 str. E2348/69 7064265 YP_002330715.1 CDS gspH NC_011601.1 3371836 3372399 R type II secretion protein complement(3371836..3372399) Escherichia coli O127:H6 str. E2348/69 7064264 YP_002330716.1 CDS gspG NC_011601.1 3372403 3372858 R type II secretion protein complement(3372403..3372858) Escherichia coli O127:H6 str. E2348/69 7064263 YP_002330717.1 CDS gspF NC_011601.1 3372875 3374098 R type II secretion protein complement(3372875..3374098) Escherichia coli O127:H6 str. E2348/69 7064262 YP_002330718.1 CDS gspE NC_011601.1 3374098 3375591 R type II secretion protein complement(3374098..3375591) Escherichia coli O127:H6 str. E2348/69 7064261 YP_002330719.1 CDS gspD NC_011601.1 3375591 3377651 R type II secretion protein complement(3375591..3377651) Escherichia coli O127:H6 str. E2348/69 7064260 YP_002330720.1 CDS gspC NC_011601.1 3377681 3378640 R part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC complement(3377681..3378640) Escherichia coli O127:H6 str. E2348/69 7064259 YP_002330721.1 CDS yghG NC_011601.1 3378658 3379068 R hypothetical protein complement(3378658..3379068) Escherichia coli O127:H6 str. E2348/69 7064258 YP_002330722.1 CDS pppA NC_011601.1 3379134 3379943 R bifunctional prepilin leader peptidase/methylase complement(3379134..3379943) Escherichia coli O127:H6 str. E2348/69 7063380 YP_002330723.1 CDS yghJ NC_011601.1 3380138 3384712 R inner membrane lipoprotein complement(3380138..3384712) Escherichia coli O127:H6 str. E2348/69 7061275 YP_002330724.1 CDS glcA NC_011601.1 3385198 3386880 R glycolate transporter complement(3385198..3386880) Escherichia coli O127:H6 str. E2348/69 7063381 YP_002330725.1 CDS glcB NC_011601.1 3387235 3389406 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3387235..3389406) Escherichia coli O127:H6 str. E2348/69 7061152 YP_002330726.1 CDS glcG NC_011601.1 3389428 3389832 R hypothetical protein complement(3389428..3389832) Escherichia coli O127:H6 str. E2348/69 7061659 YP_002330727.1 CDS glcF NC_011601.1 3389837 3391060 R glycolate oxidase iron-sulfur subunit complement(3389837..3391060) Escherichia coli O127:H6 str. E2348/69 7061664 YP_002330728.1 CDS glcE NC_011601.1 3391071 3392123 R glycolate oxidase FAD binding subunit complement(3391071..3392123) Escherichia coli O127:H6 str. E2348/69 7061663 YP_002330729.1 CDS glcD NC_011601.1 3392123 3393622 R glycolate oxidase subunit GlcD complement(3392123..3393622) Escherichia coli O127:H6 str. E2348/69 7061662 YP_002330730.1 CDS glcC NC_011601.1 3393873 3394637 D DNA-binding transcriptional regulator GlcC 3393873..3394637 Escherichia coli O127:H6 str. E2348/69 7061661 YP_002330731.1 CDS yghO NC_011601.1 3394644 3395786 R DNA-binding transcriptional regulator complement(3394644..3395786) Escherichia coli O127:H6 str. E2348/69 7061660 YP_002330732.1 CDS E2348C_3262 NC_011601.1 3396139 3397872 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3396139..3397872 Escherichia coli O127:H6 str. E2348/69 7063382 YP_002330733.1 CDS E2348C_3263 NC_011601.1 3397869 3398783 D hypothetical protein 3397869..3398783 Escherichia coli O127:H6 str. E2348/69 7062608 YP_002330734.1 CDS E2348C_3264 NC_011601.1 3398815 3399063 D acyl carrier protein 3398815..3399063 Escherichia coli O127:H6 str. E2348/69 7062609 YP_002330735.1 CDS E2348C_3265 NC_011601.1 3399063 3400235 D aminotransferase 3399063..3400235 Escherichia coli O127:H6 str. E2348/69 7062610 YP_002330736.1 CDS E2348C_3266 NC_011601.1 3400270 3401349 R permease complement(3400270..3401349) Escherichia coli O127:H6 str. E2348/69 7062611 YP_002330737.1 CDS E2348C_3267 NC_011601.1 3401346 3402416 R permease complement(3401346..3402416) Escherichia coli O127:H6 str. E2348/69 7062612 YP_002330738.1 CDS E2348C_3268 NC_011601.1 3402446 3403006 R transcriptional regulator complement(3402446..3403006) Escherichia coli O127:H6 str. E2348/69 7062613 YP_002330739.1 CDS E2348C_3269 NC_011601.1 3403018 3403842 R hypothetical protein complement(3403018..3403842) Escherichia coli O127:H6 str. E2348/69 7062614 YP_002330740.1 CDS yghQ NC_011601.1 3403842 3405191 R hypothetical protein complement(3403842..3405191) Escherichia coli O127:H6 str. E2348/69 7062615 YP_002330741.1 CDS yghR NC_011601.1 3405237 3405995 R hypothetical protein complement(3405237..3405995) Escherichia coli O127:H6 str. E2348/69 7063383 YP_002330742.1 CDS yghS NC_011601.1 3406027 3406740 R hypothetical protein complement(3406027..3406740) Escherichia coli O127:H6 str. E2348/69 7063384 YP_002330743.1 CDS yghT NC_011601.1 3406915 3407607 D hypothetical protein 3406915..3407607 Escherichia coli O127:H6 str. E2348/69 7063385 YP_002330744.1 CDS pitB NC_011601.1 3407656 3409155 R phosphate transporter complement(3407656..3409155) Escherichia coli O127:H6 str. E2348/69 7063386 YP_002330745.1 CDS gsp NC_011601.1 3409446 3411305 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3409446..3411305) Escherichia coli O127:H6 str. E2348/69 7060753 YP_002330746.1 CDS yghU NC_011601.1 3411510 3412376 D YghU; B2989; one of eight glutathione transferases from E. coli; glutathione S-transferase 3411510..3412376 Escherichia coli O127:H6 str. E2348/69 7064257 YP_002330747.1 CDS hybG NC_011601.1 3412518 3412766 R hydrogenase 2 accessory protein HypG complement(3412518..3412766) Escherichia coli O127:H6 str. E2348/69 7063387 YP_002330748.1 CDS hybF NC_011601.1 3412779 3413120 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3412779..3413120) Escherichia coli O127:H6 str. E2348/69 7062207 YP_002330749.1 CDS hybE NC_011601.1 3413113 3413601 R hydrogenase 2-specific chaperone complement(3413113..3413601) Escherichia coli O127:H6 str. E2348/69 7062206 YP_002330750.1 CDS hybD NC_011601.1 3413594 3414088 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3413594..3414088) Escherichia coli O127:H6 str. E2348/69 7062205 YP_002330751.1 CDS hybC NC_011601.1 3414088 3415791 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3414088..3415791) Escherichia coli O127:H6 str. E2348/69 7062204 YP_002330752.1 CDS hybB NC_011601.1 3415788 3416966 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3415788..3416966) Escherichia coli O127:H6 str. E2348/69 7062203 YP_002330753.1 CDS hybA NC_011601.1 3416956 3417942 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3416956..3417942) Escherichia coli O127:H6 str. E2348/69 7062202 YP_002330754.1 CDS hybO NC_011601.1 3417945 3419063 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3417945..3419063) Escherichia coli O127:H6 str. E2348/69 7062201 YP_002330755.1 CDS yghW NC_011601.1 3419252 3419539 R hypothetical protein complement(3419252..3419539) Escherichia coli O127:H6 str. E2348/69 7062208 YP_002330756.1 CDS yghX NC_011601.1 3419658 3420545 R hydrolase complement(3419658..3420545) Escherichia coli O127:H6 str. E2348/69 7063388 YP_002330757.1 CDS E2348C_3288 NC_011601.1 3421062 3421583 D transposase Orf1 of IS1397 3421062..3421583 Escherichia coli O127:H6 str. E2348/69 7061125 YP_002330758.1 CDS E2348C_3289 NC_011601.1 3421685 3422407 D transposase Orf2 of IS1397 3421685..3422407 Escherichia coli O127:H6 str. E2348/69 7062616 YP_002330759.1 CDS yqhA NC_011601.1 3423214 3423708 R hypothetical protein complement(3423214..3423708) Escherichia coli O127:H6 str. E2348/69 7062617 YP_002330760.1 CDS yghA NC_011601.1 3423899 3424783 D oxidoreductase 3423899..3424783 Escherichia coli O127:H6 str. E2348/69 7063195 YP_002330761.1 CDS exbD NC_011601.1 3424822 3425247 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3424822..3425247) Escherichia coli O127:H6 str. E2348/69 7063378 YP_002330762.1 CDS exbB NC_011601.1 3425254 3425988 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3425254..3425988) Escherichia coli O127:H6 str. E2348/69 7063906 YP_002330763.1 CDS metC NC_011601.1 3426240 3427427 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3426240..3427427 Escherichia coli O127:H6 str. E2348/69 7063905 YP_002330764.1 CDS yghB NC_011601.1 3427567 3428226 D hypothetical protein 3427567..3428226 Escherichia coli O127:H6 str. E2348/69 7063758 YP_002330765.1 CDS yqhC NC_011601.1 3428266 3429222 R DNA-binding transcriptional regulator complement(3428266..3429222) Escherichia coli O127:H6 str. E2348/69 7063379 YP_002330766.1 CDS yqhD NC_011601.1 3429359 3430522 D alcohol dehydrogenase 3429359..3430522 Escherichia coli O127:H6 str. E2348/69 7063196 YP_002330767.1 CDS dkgA NC_011601.1 3430627 3431454 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3430627..3431454 Escherichia coli O127:H6 str. E2348/69 7063197 YP_002330768.1 CDS yqhG NC_011601.1 3431654 3432580 D hypothetical protein 3431654..3432580 Escherichia coli O127:H6 str. E2348/69 7065036 YP_002330769.1 CDS yqhH NC_011601.1 3432631 3432888 D outer membrane lipoprotein 3432631..3432888 Escherichia coli O127:H6 str. E2348/69 7063198 YP_002330770.1 CDS ygiQ NC_011601.1 3432930 3435149 R hypothetical protein complement(3432930..3435149) Escherichia coli O127:H6 str. E2348/69 7063199 YP_002330771.1 CDS E2348C_3302 NC_011601.1 3435401 3436150 D regulator 3435401..3436150 Escherichia coli O127:H6 str. E2348/69 7063396 YP_002330772.1 CDS E2348C_3303 NC_011601.1 3436473 3437945 D mannitol dehydrogenase-family protein 3436473..3437945 Escherichia coli O127:H6 str. E2348/69 7062618 YP_002330773.1 CDS E2348C_3304 NC_011601.1 3437942 3438958 D zinc-binding dehydrogenase 3437942..3438958 Escherichia coli O127:H6 str. E2348/69 7062619 YP_002330774.1 CDS E2348C_3305 NC_011601.1 3438969 3439979 D malate/L-lactate dehydrogenase-family protein 3438969..3439979 Escherichia coli O127:H6 str. E2348/69 7062620 YP_002330775.1 CDS E2348C_3306 NC_011601.1 3440052 3441035 D TRAP-type C4-dicarboxylate transport system, periplasmic component 3440052..3441035 Escherichia coli O127:H6 str. E2348/69 7062621 YP_002330776.1 CDS E2348C_3307 NC_011601.1 3441077 3441559 D TRAP-type C4-dicarboxylate transport system, small permease component 3441077..3441559 Escherichia coli O127:H6 str. E2348/69 7062622 YP_002330777.1 CDS E2348C_3308 NC_011601.1 3441570 3442874 D TRAP-type C4-dicarboxylate transport system, large permease component 3441570..3442874 Escherichia coli O127:H6 str. E2348/69 7062623 YP_002330778.1 CDS sufI NC_011601.1 3442945 3444357 R repressor protein for FtsI complement(3442945..3444357) Escherichia coli O127:H6 str. E2348/69 7062625 YP_002330779.1 CDS plsC NC_011601.1 3444432 3445169 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3444432..3445169) Escherichia coli O127:H6 str. E2348/69 7061739 YP_002330780.1 CDS parC NC_011601.1 3445404 3447662 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3445404..3447662) Escherichia coli O127:H6 str. E2348/69 7060757 YP_002330781.1 CDS ygiS NC_011601.1 3447800 3449407 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein complement(3447800..3449407) Escherichia coli O127:H6 str. E2348/69 7062911 YP_002330782.1 CDS ygiV NC_011601.1 3449516 3449998 R transcriptional regulator complement(3449516..3449998) Escherichia coli O127:H6 str. E2348/69 7063397 YP_002330783.1 CDS ygiW NC_011601.1 3450051 3450443 R hypothetical protein complement(3450051..3450443) Escherichia coli O127:H6 str. E2348/69 7063398 YP_002330784.1 CDS qseB NC_011601.1 3450595 3451254 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3450595..3451254 Escherichia coli O127:H6 str. E2348/69 7063399 YP_002330785.1 CDS qseC NC_011601.1 3451251 3452600 D sensor protein QseC 3451251..3452600 Escherichia coli O127:H6 str. E2348/69 7063939 YP_002330786.1 CDS mdaB NC_011601.1 3452710 3453291 D NADPH quinone reductase 3452710..3453291 Escherichia coli O127:H6 str. E2348/69 7063940 YP_002330787.1 CDS ygiN NC_011601.1 3453322 3453636 D quinol monooxygenase 3453322..3453636 Escherichia coli O127:H6 str. E2348/69 7065297 YP_002330788.1 CDS E2348C_3319 NC_011601.1 3453681 3454568 R transcriptional regulator complement(3453681..3454568) Escherichia coli O127:H6 str. E2348/69 7063395 YP_002330789.1 CDS E2348C_3320 NC_011601.1 3454565 3455512 R ferrichrome-binding protein complement(3454565..3455512) Escherichia coli O127:H6 str. E2348/69 7062626 YP_002330790.1 CDS E2348C_3321 NC_011601.1 3455523 3456572 R permease of ferrichrome ABC transporter complement(3455523..3456572) Escherichia coli O127:H6 str. E2348/69 7062627 YP_002330791.1 CDS E2348C_3322 NC_011601.1 3456569 3457552 R permease of ferrichrome ABC transporter complement(3456569..3457552) Escherichia coli O127:H6 str. E2348/69 7062628 YP_002330792.1 CDS E2348C_3323 NC_011601.1 3457549 3458358 R ABC-type iron-siderophore transport system ATP-binding protein complement(3457549..3458358) Escherichia coli O127:H6 str. E2348/69 7062629 YP_002330793.1 CDS E2348C_3324 NC_011601.1 3458732 3460873 D ferrichrome iron receptor 3458732..3460873 Escherichia coli O127:H6 str. E2348/69 7062630 YP_002330794.1 CDS parE NC_011601.1 3460938 3462830 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3460938..3462830) Escherichia coli O127:H6 str. E2348/69 7062631 YP_002330795.1 CDS yqiA NC_011601.1 3462859 3463440 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(3462859..3463440) Escherichia coli O127:H6 str. E2348/69 7062912 YP_002330796.1 CDS cpdA NC_011601.1 3463440 3464267 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3463440..3464267) Escherichia coli O127:H6 str. E2348/69 7063200 YP_002330797.1 CDS yqiB NC_011601.1 3464292 3464714 R hypothetical protein complement(3464292..3464714) Escherichia coli O127:H6 str. E2348/69 7062834 YP_002330798.1 CDS nudF NC_011601.1 3464715 3465344 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase complement(3464715..3465344) Escherichia coli O127:H6 str. E2348/69 7063201 YP_002330799.1 CDS tolC NC_011601.1 3465549 3467030 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3465549..3467030 Escherichia coli O127:H6 str. E2348/69 7065430 YP_002330800.1 CDS E2348C_3331 NC_011601.1 3467030 3467290 D hypothetical protein 3467030..3467290 Escherichia coli O127:H6 str. E2348/69 7061814 YP_002330801.1 CDS ygiB NC_011601.1 3467178 3467849 D hypothetical protein 3467178..3467849 Escherichia coli O127:H6 str. E2348/69 7062632 YP_002330802.1 CDS ygiC NC_011601.1 3467855 3469015 D hypothetical protein 3467855..3469015 Escherichia coli O127:H6 str. E2348/69 7063390 YP_002330803.1 CDS E2348C_3334 NC_011601.1 3469500 3471296 D arylsulfate sulfotransferase 3469500..3471296 Escherichia coli O127:H6 str. E2348/69 7063391 YP_002330804.1 CDS E2348C_3335 NC_011601.1 3471314 3471982 D disulfide isomerase, DsbA family 3471314..3471982 Escherichia coli O127:H6 str. E2348/69 7062633 YP_002330805.1 CDS E2348C_3336 NC_011601.1 3471997 3472668 D disulfide oxidoreductase 3471997..3472668 Escherichia coli O127:H6 str. E2348/69 7062634 YP_002330806.1 CDS ygiD NC_011601.1 3472714 3473529 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3472714..3473529) Escherichia coli O127:H6 str. E2348/69 7062635 YP_002330807.1 CDS zupT NC_011601.1 3473645 3474418 D zinc transporter ZupT 3473645..3474418 Escherichia coli O127:H6 str. E2348/69 7063392 YP_002330808.1 CDS E2348C_3339 NC_011601.1 3474476 3474646 R hypothetical protein complement(3474476..3474646) Escherichia coli O127:H6 str. E2348/69 7062541 YP_002330809.1 CDS ribB NC_011601.1 3474908 3475561 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3474908..3475561) Escherichia coli O127:H6 str. E2348/69 7062636 YP_002330810.1 CDS yqiC NC_011601.1 3475935 3476234 D hypothetical protein 3475935..3476234 Escherichia coli O127:H6 str. E2348/69 7061153 YP_002330811.1 CDS glgS NC_011601.1 3476269 3476469 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3476269..3476469) Escherichia coli O127:H6 str. E2348/69 7063202 YP_002330812.1 CDS yqiJ NC_011601.1 3476739 3477368 D hypothetical protein 3476739..3477368 Escherichia coli O127:H6 str. E2348/69 7061670 YP_002330813.1 CDS yqiK NC_011601.1 3477395 3479056 D hypothetical protein 3477395..3479056 Escherichia coli O127:H6 str. E2348/69 7063203 YP_002330814.1 CDS rfaE NC_011601.1 3479475 3480908 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3479475..3480908) Escherichia coli O127:H6 str. E2348/69 7064603 YP_002330815.1 CDS glnE NC_011601.1 3480956 3483796 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3480956..3483796) Escherichia coli O127:H6 str. E2348/69 7060782 YP_002330816.1 CDS ygiF NC_011601.1 3483819 3485120 R adenylate cyclase complement(3483819..3485120) Escherichia coli O127:H6 str. E2348/69 7061679 YP_002330817.1 CDS htrG NC_011601.1 3485362 3485982 D signal transduction protein 3485362..3485982 Escherichia coli O127:H6 str. E2348/69 7063393 YP_002330818.1 CDS cca NC_011601.1 3486046 3487284 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3486046..3487284 Escherichia coli O127:H6 str. E2348/69 7062192 YP_002330819.1 CDS bacA NC_011601.1 3487364 3488185 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3487364..3488185) Escherichia coli O127:H6 str. E2348/69 7064331 YP_002330820.1 CDS folB NC_011601.1 3488276 3488644 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3488276..3488644) Escherichia coli O127:H6 str. E2348/69 7062490 YP_002330821.1 CDS ygiH NC_011601.1 3488749 3489366 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3488749..3489366 Escherichia coli O127:H6 str. E2348/69 7061939 YP_002330822.1 CDS ttdR NC_011601.1 3489379 3490311 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3489379..3490311) Escherichia coli O127:H6 str. E2348/69 7063394 YP_002330823.1 CDS ttdA NC_011601.1 3490518 3491429 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3490518..3491429 Escherichia coli O127:H6 str. E2348/69 7062277 YP_002330824.1 CDS ttdB NC_011601.1 3491426 3492031 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3491426..3492031 Escherichia coli O127:H6 str. E2348/69 7062275 YP_002330825.1 CDS ttdT NC_011601.1 3492079 3493542 D tartrate: succinate antiporter 3492079..3493542 Escherichia coli O127:H6 str. E2348/69 7062276 YP_002330826.1 CDS ygjD NC_011601.1 3493585 3494598 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3493585..3494598) Escherichia coli O127:H6 str. E2348/69 7062278 YP_002330827.1 CDS rpsU NC_011601.1 3494836 3495051 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3494836..3495051 Escherichia coli O127:H6 str. E2348/69 7063400 YP_002330828.1 CDS dnaG NC_011601.1 3495162 3496907 D synthesizes RNA primers at the replication forks; DNA primase 3495162..3496907 Escherichia coli O127:H6 str. E2348/69 7061893 YP_002330829.1 CDS rpoD NC_011601.1 3497102 3498943 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3497102..3498943 Escherichia coli O127:H6 str. E2348/69 7065048 YP_002330830.1 CDS E2348C_3361 NC_011601.1 3499002 3499565 D hypothetical protein 3499002..3499565 Escherichia coli O127:H6 str. E2348/69 7061866 YP_002330831.1 CDS yqjH NC_011601.1 3500372 3501136 R siderophore interacting protein complement(3500372..3501136) Escherichia coli O127:H6 str. E2348/69 7063527 YP_002330832.1 CDS yqjI NC_011601.1 3501424 3502047 D transcriptional regulator 3501424..3502047 Escherichia coli O127:H6 str. E2348/69 7063212 YP_002330833.1 CDS aer NC_011601.1 3502076 3503596 R fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component complement(3502076..3503596) Escherichia coli O127:H6 str. E2348/69 7063213 YP_002330834.1 CDS ygjG NC_011601.1 3504014 3505393 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3504014..3505393 Escherichia coli O127:H6 str. E2348/69 7062414 YP_002330835.1 CDS ygjH NC_011601.1 3505435 3505767 R hypothetical protein complement(3505435..3505767) Escherichia coli O127:H6 str. E2348/69 7063401 YP_002330836.1 CDS ebgR NC_011601.1 3505986 3506969 D DNA-binding transcriptional repressor EbgR 3505986..3506969 Escherichia coli O127:H6 str. E2348/69 7063402 YP_002330837.1 CDS ebgA NC_011601.1 3507153 3510245 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3507153..3510245 Escherichia coli O127:H6 str. E2348/69 7065082 YP_002330838.1 CDS ebgC NC_011601.1 3510242 3510691 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3510242..3510691 Escherichia coli O127:H6 str. E2348/69 7065080 YP_002330839.1 CDS ygjI NC_011601.1 3510754 3512187 D transporter 3510754..3512187 Escherichia coli O127:H6 str. E2348/69 7065081 YP_002330840.1 CDS ygjJ NC_011601.1 3512321 3513391 D hypothetical protein 3512321..3513391 Escherichia coli O127:H6 str. E2348/69 7063403 YP_002330841.1 CDS ygjK NC_011601.1 3513408 3515759 D glycosyl hydrolase 3513408..3515759 Escherichia coli O127:H6 str. E2348/69 7063404 YP_002330842.1 CDS fadH NC_011601.1 3516083 3518101 D 2,4-dienoyl-CoA reductase 3516083..3518101 Escherichia coli O127:H6 str. E2348/69 7063405 YP_002330843.1 CDS ygjM NC_011601.1 3518146 3518562 R DNA-binding transcriptional regulator complement(3518146..3518562) Escherichia coli O127:H6 str. E2348/69 7062075 YP_002330844.1 CDS rlmG NC_011601.1 3518833 3519969 R methyltransferase small domain complement(3518833..3519969) Escherichia coli O127:H6 str. E2348/69 7063406 YP_002330845.1 CDS ygjP NC_011601.1 3520054 3520557 D metal dependent hydrolase 3520054..3520557 Escherichia coli O127:H6 str. E2348/69 7060834 YP_002330846.1 CDS ygjQ NC_011601.1 3520634 3521326 D thioredoxin-like protein 3520634..3521326 Escherichia coli O127:H6 str. E2348/69 7063407 YP_002330847.1 CDS ygjR NC_011601.1 3521405 3522391 D NAD(P)-binding dehydrogenase 3521405..3522391 Escherichia coli O127:H6 str. E2348/69 7063408 YP_002330848.1 CDS alx NC_011601.1 3522674 3523639 D hypothetical protein 3522674..3523639 Escherichia coli O127:H6 str. E2348/69 7061326 YP_002330849.1 CDS E2348C_3381 NC_011601.1 3523876 3525249 D transposase of ISEc13 3523876..3525249 Escherichia coli O127:H6 str. E2348/69 7061126 YP_002330850.1 CDS sstT NC_011601.1 3525523 3526767 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3525523..3526767 Escherichia coli O127:H6 str. E2348/69 7062638 YP_002330851.1 CDS ygjV NC_011601.1 3526771 3527322 R hypothetical protein complement(3526771..3527322) Escherichia coli O127:H6 str. E2348/69 7062769 YP_002330852.1 CDS uxaA NC_011601.1 3527405 3528892 R altronate hydrolase complement(3527405..3528892) Escherichia coli O127:H6 str. E2348/69 7063410 YP_002330853.1 CDS uxaC NC_011601.1 3528907 3530319 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3528907..3530319) Escherichia coli O127:H6 str. E2348/69 7062345 YP_002330854.1 CDS exuT NC_011601.1 3530678 3532096 D hexuronate transporter 3530678..3532096 Escherichia coli O127:H6 str. E2348/69 7062347 YP_002330855.1 CDS exuR NC_011601.1 3532226 3533002 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3532226..3533002 Escherichia coli O127:H6 str. E2348/69 7062061 YP_002330856.1 CDS yqjA NC_011601.1 3533347 3534009 D hypothetical protein 3533347..3534009 Escherichia coli O127:H6 str. E2348/69 7062059 YP_002330857.1 CDS yqjB NC_011601.1 3534013 3534396 D hypothetical protein 3534013..3534396 Escherichia coli O127:H6 str. E2348/69 7063205 YP_002330858.1 CDS yqjC NC_011601.1 3534543 3534911 D hypothetical protein 3534543..3534911 Escherichia coli O127:H6 str. E2348/69 7063206 YP_002330859.1 CDS yqjD NC_011601.1 3534949 3535254 D hypothetical protein 3534949..3535254 Escherichia coli O127:H6 str. E2348/69 7063207 YP_002330860.1 CDS yqjE NC_011601.1 3535257 3535661 D hypothetical protein 3535257..3535661 Escherichia coli O127:H6 str. E2348/69 7063208 YP_002330861.1 CDS yqjK NC_011601.1 3535651 3535950 D hypothetical protein 3535651..3535950 Escherichia coli O127:H6 str. E2348/69 7063209 YP_002330862.1 CDS yqjF NC_011601.1 3536137 3536529 D quinol oxidase subunit 3536137..3536529 Escherichia coli O127:H6 str. E2348/69 7063214 YP_002330863.1 CDS yqjG NC_011601.1 3536599 3537585 D S-transferase 3536599..3537585 Escherichia coli O127:H6 str. E2348/69 7063210 YP_002330864.1 CDS yhaH NC_011601.1 3537868 3538236 D hypothetical protein 3537868..3538236 Escherichia coli O127:H6 str. E2348/69 7063211 YP_002330865.1 CDS yhaJ NC_011601.1 3538270 3539166 R DNA-binding transcriptional regulator complement(3538270..3539166) Escherichia coli O127:H6 str. E2348/69 7063411 YP_002330866.1 CDS yhaK NC_011601.1 3539271 3539972 D pirin 3539271..3539972 Escherichia coli O127:H6 str. E2348/69 7063412 YP_002330867.1 CDS yhaL NC_011601.1 3539995 3540159 D hypothetical protein 3539995..3540159 Escherichia coli O127:H6 str. E2348/69 7063413 YP_002330868.1 CDS yhaM NC_011601.1 3540291 3541601 R hypothetical protein complement(3540291..3541601) Escherichia coli O127:H6 str. E2348/69 7063414 YP_002330869.1 CDS yhaO NC_011601.1 3541629 3542960 R transporter complement(3541629..3542960) Escherichia coli O127:H6 str. E2348/69 7063415 YP_002330870.1 CDS tdcG NC_011601.1 3543238 3544602 R L-serine dehydratase 3 complement(3543238..3544602) Escherichia coli O127:H6 str. E2348/69 7063416 YP_002330871.1 CDS tdcF NC_011601.1 3544674 3545063 R hypothetical protein complement(3544674..3545063) Escherichia coli O127:H6 str. E2348/69 7061771 YP_002330872.1 CDS tdcE NC_011601.1 3545077 3547371 R pyruvate formate-lyase 4/2-ketobutyrate formate-lyase complement(3545077..3547371) Escherichia coli O127:H6 str. E2348/69 7061770 YP_002330873.1 CDS tdcD NC_011601.1 3547405 3548613 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3547405..3548613) Escherichia coli O127:H6 str. E2348/69 7061769 YP_002330874.1 CDS tdcC NC_011601.1 3548639 3549970 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3548639..3549970) Escherichia coli O127:H6 str. E2348/69 7061768 YP_002330875.1 CDS tdcB NC_011601.1 3549992 3550981 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3549992..3550981) Escherichia coli O127:H6 str. E2348/69 7061767 YP_002330876.1 CDS tdcA NC_011601.1 3551080 3552018 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3551080..3552018) Escherichia coli O127:H6 str. E2348/69 7061766 YP_002330877.1 CDS tdcR NC_011601.1 3552333 3552551 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3552333..3552551 Escherichia coli O127:H6 str. E2348/69 7061765 YP_002330878.1 CDS garK NC_011601.1 3553517 3554662 R glycerate kinase complement(3553517..3554662) Escherichia coli O127:H6 str. E2348/69 7060857 YP_002330879.1 CDS garR NC_011601.1 3554759 3555649 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3554759..3555649) Escherichia coli O127:H6 str. E2348/69 7061628 YP_002330880.1 CDS garL NC_011601.1 3555679 3556449 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3555679..3556449) Escherichia coli O127:H6 str. E2348/69 7061631 YP_002330881.1 CDS garP NC_011601.1 3556465 3557799 R (D)-galactarate transporter complement(3556465..3557799) Escherichia coli O127:H6 str. E2348/69 7061629 YP_002330882.1 CDS garD NC_011601.1 3558174 3559745 D (D)-galactarate dehydrogenase 3558174..3559745 Escherichia coli O127:H6 str. E2348/69 7061630 YP_002330883.1 CDS agaR NC_011601.1 3559797 3560621 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3559797..3560621) Escherichia coli O127:H6 str. E2348/69 7061627 YP_002330884.1 CDS kbaZ NC_011601.1 3560870 3562150 D tagatose 6-phosphate aldolase 1, kbaZ subunit 3560870..3562150 Escherichia coli O127:H6 str. E2348/69 7062421 YP_002330885.1 CDS agaV NC_011601.1 3562173 3562646 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3562173..3562646 Escherichia coli O127:H6 str. E2348/69 7063566 YP_002330886.1 CDS agaW NC_011601.1 3562657 3563442 D N-acetylgalactosamine-specific enzyme IIC component of PTS 3562657..3563442 Escherichia coli O127:H6 str. E2348/69 7062423 YP_002330887.1 CDS E2348C_3419 NC_011601.1 3563432 3564310 D N-acetylgalactosamine-specific PTS system enzyme IID component 3563432..3564310 Escherichia coli O127:H6 str. E2348/69 7062424 YP_002330888.1 CDS E2348C_3420 NC_011601.1 3564328 3564762 D N-acetyl-galactosamine/galactosamine PTS system enzyme IIA component 3564328..3564762 Escherichia coli O127:H6 str. E2348/69 7062639 YP_002330889.1 CDS agaA NC_011601.1 3564759 3565892 D N-acetylgalactosamine-6-sulfatase 3564759..3565892 Escherichia coli O127:H6 str. E2348/69 7062640 YP_002330890.1 CDS agaS NC_011601.1 3566241 3567395 D tagatose-6-phosphate ketose/aldose isomerase 3566241..3567395 Escherichia coli O127:H6 str. E2348/69 7062416 YP_002330891.1 CDS kbaY NC_011601.1 3567408 3568268 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3567408..3568268 Escherichia coli O127:H6 str. E2348/69 7062422 YP_002330892.1 CDS agaB NC_011601.1 3568435 3568911 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3568435..3568911 Escherichia coli O127:H6 str. E2348/69 7063565 YP_002330893.1 CDS agaC NC_011601.1 3568950 3569753 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3568950..3569753 Escherichia coli O127:H6 str. E2348/69 7062417 YP_002330894.1 CDS agaD NC_011601.1 3569743 3570534 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3569743..3570534 Escherichia coli O127:H6 str. E2348/69 7062418 YP_002330895.1 CDS agaI NC_011601.1 3570589 3571302 D galactosamine-6-phosphate isomerase 3570589..3571302 Escherichia coli O127:H6 str. E2348/69 7062419 YP_002330896.1 CDS yraL NC_011601.1 3571352 3572215 R methyltransferase complement(3571352..3572215) Escherichia coli O127:H6 str. E2348/69 7062420 YP_002330897.1 CDS yraM NC_011601.1 3572280 3574316 D hypothetical protein 3572280..3574316 Escherichia coli O127:H6 str. E2348/69 7063215 YP_002330898.1 CDS yraN NC_011601.1 3574274 3574669 D hypothetical protein 3574274..3574669 Escherichia coli O127:H6 str. E2348/69 7063216 YP_002330899.1 CDS diaA NC_011601.1 3574689 3575279 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3574689..3575279 Escherichia coli O127:H6 str. E2348/69 7063217 YP_002330900.1 CDS yraP NC_011601.1 3575289 3575864 D hypothetical protein 3575289..3575864 Escherichia coli O127:H6 str. E2348/69 7065025 YP_002330901.1 CDS yraQ NC_011601.1 3575977 3577023 R permease complement(3575977..3577023) Escherichia coli O127:H6 str. E2348/69 7063218 YP_002330902.1 CDS yraR NC_011601.1 3577096 3577731 R nucleoside-diphosphate-sugarepimerase complement(3577096..3577731) Escherichia coli O127:H6 str. E2348/69 7063219 YP_002330903.1 CDS yhbP NC_011601.1 3577773 3578195 R hypothetical protein complement(3577773..3578195) Escherichia coli O127:H6 str. E2348/69 7063220 YP_002330904.1 CDS yhbQ NC_011601.1 3578246 3578548 D GIY-YIG nuclease superfamily protein 3578246..3578548 Escherichia coli O127:H6 str. E2348/69 7063420 YP_002330905.1 CDS yhbS NC_011601.1 3578535 3579038 R acyltransferase complement(3578535..3579038) Escherichia coli O127:H6 str. E2348/69 7063421 YP_002330906.1 CDS yhbT NC_011601.1 3579032 3579556 R lipid carrier protein complement(3579032..3579556) Escherichia coli O127:H6 str. E2348/69 7063422 YP_002330907.1 CDS yhbU NC_011601.1 3579765 3580760 D peptidase (collagenase-like) 3579765..3580760 Escherichia coli O127:H6 str. E2348/69 7063423 YP_002330908.1 CDS yhbV NC_011601.1 3580769 3581647 D protease 3580769..3581647 Escherichia coli O127:H6 str. E2348/69 7064446 YP_002330909.1 CDS yhbW NC_011601.1 3581728 3582735 D hypothetical protein 3581728..3582735 Escherichia coli O127:H6 str. E2348/69 7064605 YP_002330910.1 CDS mtr NC_011601.1 3582853 3584097 R tryptophan transporter of high affinity; tryptophan permease complement(3582853..3584097) Escherichia coli O127:H6 str. E2348/69 7064606 YP_002330911.1 CDS deaD NC_011601.1 3584251 3586140 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3584251..3586140) Escherichia coli O127:H6 str. E2348/69 7060882 YP_002330912.1 CDS nlpI NC_011601.1 3586320 3587204 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3586320..3587204) Escherichia coli O127:H6 str. E2348/69 7065239 YP_002330913.1 CDS pnp NC_011601.1 3587313 3589448 R polynucleotide phosphorylase complement(3587313..3589448) Escherichia coli O127:H6 str. E2348/69 7065405 YP_002330914.1 CDS rpsO NC_011601.1 3589695 3589964 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3589695..3589964) Escherichia coli O127:H6 str. E2348/69 7061327 YP_002330915.1 CDS truB NC_011601.1 3590113 3591057 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3590113..3591057) Escherichia coli O127:H6 str. E2348/69 7061154 YP_002330916.1 CDS rbfA NC_011601.1 3591057 3591458 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3591057..3591458) Escherichia coli O127:H6 str. E2348/69 7062264 YP_002330917.1 CDS infB NC_011601.1 3591622 3594294 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3591622..3594294) Escherichia coli O127:H6 str. E2348/69 7063952 YP_002330918.1 CDS nusA NC_011601.1 3594319 3595806 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3594319..3595806) Escherichia coli O127:H6 str. E2348/69 7063543 YP_002330919.1 CDS yhbC NC_011601.1 3595834 3596256 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3595834..3596256) Escherichia coli O127:H6 str. E2348/69 7062868 YP_002330920.1 CDS argG NC_011601.1 3596917 3598260 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3596917..3598260 Escherichia coli O127:H6 str. E2348/69 7063774 YP_002330921.1 CDS yhbX NC_011601.1 3598268 3599893 R hydrolase, inner membrane complement(3598268..3599893) Escherichia coli O127:H6 str. E2348/69 7061370 YP_002330922.1 CDS secG NC_011601.1 3600451 3600783 R preprotein translocase subunit SecG complement(3600451..3600783) Escherichia coli O127:H6 str. E2348/69 7061532 YP_002330923.1 CDS glmM NC_011601.1 3601011 3602348 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3601011..3602348) Escherichia coli O127:H6 str. E2348/69 7065357 YP_002330924.1 CDS folP NC_011601.1 3602341 3603189 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3602341..3603189) Escherichia coli O127:H6 str. E2348/69 7061673 YP_002330925.1 CDS hflB NC_011601.1 3603279 3605213 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3603279..3605213) Escherichia coli O127:H6 str. E2348/69 7061945 YP_002330926.1 CDS rrmJ NC_011601.1 3605313 3605942 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase complement(3605313..3605942) Escherichia coli O127:H6 str. E2348/69 7064304 YP_002330927.1 CDS yhbY NC_011601.1 3606068 3606361 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3606068..3606361 Escherichia coli O127:H6 str. E2348/69 7064541 YP_002330928.1 CDS greA NC_011601.1 3606517 3606993 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3606517..3606993) Escherichia coli O127:H6 str. E2348/69 7064608 YP_002330929.1 CDS dacB NC_011601.1 3607241 3608674 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3607241..3608674 Escherichia coli O127:H6 str. E2348/69 7064239 YP_002330930.1 CDS obgE NC_011601.1 3608715 3609887 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3608715..3609887) Escherichia coli O127:H6 str. E2348/69 7065213 YP_002330931.1 CDS yhbE NC_011601.1 3609903 3610868 R hypothetical protein complement(3609903..3610868) Escherichia coli O127:H6 str. E2348/69 7062871 YP_002330932.1 CDS rpmA NC_011601.1 3610995 3611252 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3610995..3611252) Escherichia coli O127:H6 str. E2348/69 7063418 YP_002330933.1 CDS rplU NC_011601.1 3611273 3611584 R 50S ribosomal protein L21 complement(3611273..3611584) Escherichia coli O127:H6 str. E2348/69 7061853 YP_002330934.1 CDS ispB NC_011601.1 3611843 3612814 D octaprenyl diphosphate synthase 3611843..3612814 Escherichia coli O127:H6 str. E2348/69 7061848 YP_002330935.1 CDS sfsB NC_011601.1 3613048 3613326 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3613048..3613326 Escherichia coli O127:H6 str. E2348/69 7063552 YP_002330936.1 CDS murA NC_011601.1 3613374 3614633 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3613374..3614633) Escherichia coli O127:H6 str. E2348/69 7062710 YP_002330937.1 CDS yrbA NC_011601.1 3614688 3614942 R DNA-binding transcriptional regulator complement(3614688..3614942) Escherichia coli O127:H6 str. E2348/69 7060887 YP_002330938.1 CDS yrbB NC_011601.1 3615102 3615395 R hypothetical protein complement(3615102..3615395) Escherichia coli O127:H6 str. E2348/69 7063221 YP_002330939.1 CDS yrbC NC_011601.1 3615395 3616030 R ABC-type organic solvent transporter complement(3615395..3616030) Escherichia coli O127:H6 str. E2348/69 7063222 YP_002330940.1 CDS yrbD NC_011601.1 3616049 3616600 R ABC-type organic solvent transporter complement(3616049..3616600) Escherichia coli O127:H6 str. E2348/69 7063223 YP_002330941.1 CDS yrbE NC_011601.1 3616605 3617387 R toluene transporter subunit: membrane component of ABC superfamily complement(3616605..3617387) Escherichia coli O127:H6 str. E2348/69 7063224 YP_002330942.1 CDS yrbF NC_011601.1 3617395 3618204 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein complement(3617395..3618204) Escherichia coli O127:H6 str. E2348/69 7063225 YP_002330943.1 CDS yrbG NC_011601.1 3618414 3619391 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3618414..3619391 Escherichia coli O127:H6 str. E2348/69 7063226 YP_002330944.1 CDS kdsD NC_011601.1 3619405 3620391 D D-arabinose 5-phosphate isomerase 3619405..3620391 Escherichia coli O127:H6 str. E2348/69 7063227 YP_002330945.1 CDS kdsC NC_011601.1 3620412 3620978 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3620412..3620978 Escherichia coli O127:H6 str. E2348/69 7063581 YP_002330946.1 CDS yrbK NC_011601.1 3620975 3621550 D hypothetical protein 3620975..3621550 Escherichia coli O127:H6 str. E2348/69 7063580 YP_002330947.1 CDS lptA NC_011601.1 3621519 3622076 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3621519..3622076 Escherichia coli O127:H6 str. E2348/69 7063228 YP_002330948.1 CDS lptB NC_011601.1 3622083 3622808 D ABC transporter ATP-binding protein 3622083..3622808 Escherichia coli O127:H6 str. E2348/69 7061570 YP_002330949.1 CDS rpoN NC_011601.1 3622856 3624289 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3622856..3624289 Escherichia coli O127:H6 str. E2348/69 7061571 YP_002330950.1 CDS hpf NC_011601.1 3624312 3624599 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3624312..3624599 Escherichia coli O127:H6 str. E2348/69 7061869 YP_002330951.1 CDS ptsN NC_011601.1 3624717 3625208 D PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3624717..3625208 Escherichia coli O127:H6 str. E2348/69 7062176 YP_002330952.1 CDS yhbJ NC_011601.1 3625254 3626108 D hypothetical protein 3625254..3626108 Escherichia coli O127:H6 str. E2348/69 7063909 YP_002330953.1 CDS npr NC_011601.1 3626105 3626377 D phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3626105..3626377 Escherichia coli O127:H6 str. E2348/69 7063419 YP_002330954.1 CDS yrbL NC_011601.1 3626590 3627222 D hypothetical protein 3626590..3627222 Escherichia coli O127:H6 str. E2348/69 7065408 YP_002330955.1 CDS mtgA NC_011601.1 3627219 3627947 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3627219..3627947) Escherichia coli O127:H6 str. E2348/69 7063229 YP_002330956.1 CDS elbB NC_011601.1 3627944 3628597 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(3627944..3628597) Escherichia coli O127:H6 str. E2348/69 7060878 YP_002330957.1 CDS arcB NC_011601.1 3628827 3631163 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3628827..3631163) Escherichia coli O127:H6 str. E2348/69 7064604 YP_002330958.1 CDS yhcC NC_011601.1 3631259 3632188 R Fe-S oxidoreductase complement(3631259..3632188) Escherichia coli O127:H6 str. E2348/69 7061364 YP_002330959.1 CDS gltB NC_011601.1 3632770 3637323 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3632770..3637323 Escherichia coli O127:H6 str. E2348/69 7064610 YP_002330960.1 CDS gltD NC_011601.1 3637336 3638754 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3637336..3638754 Escherichia coli O127:H6 str. E2348/69 7061705 YP_002330961.1 CDS yhcH NC_011601.1 3638822 3639286 R hypothetical protein complement(3638822..3639286) Escherichia coli O127:H6 str. E2348/69 7061706 YP_002330962.1 CDS nanK NC_011601.1 3639283 3640158 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3639283..3640158) Escherichia coli O127:H6 str. E2348/69 7064611 YP_002330963.1 CDS nanE NC_011601.1 3640155 3640844 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3640155..3640844) Escherichia coli O127:H6 str. E2348/69 7060921 YP_002330964.1 CDS nanT NC_011601.1 3640892 3642382 R sialic acid transporter complement(3640892..3642382) Escherichia coli O127:H6 str. E2348/69 7060920 YP_002330965.1 CDS nanA NC_011601.1 3642491 3643384 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3642491..3643384) Escherichia coli O127:H6 str. E2348/69 7060923 YP_002330966.1 CDS nanR NC_011601.1 3643506 3644297 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3643506..3644297) Escherichia coli O127:H6 str. E2348/69 7060918 YP_002330967.1 CDS sspB NC_011601.1 3644405 3644902 R ClpXP protease specificity-enhancing factor complement(3644405..3644902) Escherichia coli O127:H6 str. E2348/69 7060922 YP_002330968.1 CDS sspA NC_011601.1 3644908 3645546 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3644908..3645546) Escherichia coli O127:H6 str. E2348/69 7062766 YP_002330969.1 CDS rpsI NC_011601.1 3645941 3646333 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3645941..3646333) Escherichia coli O127:H6 str. E2348/69 7062765 YP_002330970.1 CDS rplM NC_011601.1 3646349 3646777 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3646349..3646777) Escherichia coli O127:H6 str. E2348/69 7061881 YP_002330971.1 CDS yhcM NC_011601.1 3646997 3648124 R hypothetical protein complement(3646997..3648124) Escherichia coli O127:H6 str. E2348/69 7061840 YP_002330972.1 CDS yhcB NC_011601.1 3648318 3648716 D cytochrome d ubiquinol oxidase subunit III 3648318..3648716 Escherichia coli O127:H6 str. E2348/69 7064612 YP_002330973.1 CDS degQ NC_011601.1 3648870 3650237 D serine endoprotease 3648870..3650237 Escherichia coli O127:H6 str. E2348/69 7064609 YP_002330974.1 CDS degS NC_011601.1 3650327 3651394 D serine endoprotease 3650327..3651394 Escherichia coli O127:H6 str. E2348/69 7065005 YP_002330975.1 CDS mdh NC_011601.1 3651457 3652395 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3651457..3652395) Escherichia coli O127:H6 str. E2348/69 7065006 YP_002330976.1 CDS argR NC_011601.1 3652830 3653300 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3652830..3653300 Escherichia coli O127:H6 str. E2348/69 7065298 YP_002330977.1 CDS yhcN NC_011601.1 3653664 3653927 D hypothetical protein 3653664..3653927 Escherichia coli O127:H6 str. E2348/69 7061376 YP_002330978.1 CDS yhcO NC_011601.1 3653982 3654254 R barnase inhibitor complement(3653982..3654254) Escherichia coli O127:H6 str. E2348/69 7064613 YP_002330979.1 CDS aaeB NC_011601.1 3654346 3656313 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3654346..3656313) Escherichia coli O127:H6 str. E2348/69 7064614 YP_002330980.1 CDS aaeA NC_011601.1 3656319 3657251 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3656319..3657251) Escherichia coli O127:H6 str. E2348/69 7061175 YP_002330981.1 CDS aaeX NC_011601.1 3657259 3657462 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3657259..3657462) Escherichia coli O127:H6 str. E2348/69 7061174 YP_002330982.1 CDS aaeR NC_011601.1 3657645 3658574 D DNA-binding transcriptional regulator 3657645..3658574 Escherichia coli O127:H6 str. E2348/69 7061176 YP_002330983.1 CDS E2348C_3515 NC_011601.1 3658803 3660176 D transposase of ISEc13 3658803..3660176 Escherichia coli O127:H6 str. E2348/69 7061127 YP_002330984.1 CDS tldD NC_011601.1 3660260 3661705 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3660260..3661705) Escherichia coli O127:H6 str. E2348/69 7062641 YP_002330985.1 CDS yhdP NC_011601.1 3661861 3665661 R hypothetical protein complement(3661861..3665661) Escherichia coli O127:H6 str. E2348/69 7061808 YP_002330986.1 CDS rng NC_011601.1 3665729 3667198 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3665729..3667198) Escherichia coli O127:H6 str. E2348/69 7064620 YP_002330987.1 CDS yhdE NC_011601.1 3667188 3667781 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3667188..3667781) Escherichia coli O127:H6 str. E2348/69 7060852 YP_002330988.1 CDS mreD NC_011601.1 3667790 3668278 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3667790..3668278) Escherichia coli O127:H6 str. E2348/69 7064615 YP_002330989.1 CDS mreC NC_011601.1 3668278 3669381 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3668278..3669381) Escherichia coli O127:H6 str. E2348/69 7060869 YP_002330990.1 CDS mreB NC_011601.1 3669447 3670490 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3669447..3670490) Escherichia coli O127:H6 str. E2348/69 7060868 YP_002330991.1 CDS csrD NC_011601.1 3670795 3672735 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3670795..3672735) Escherichia coli O127:H6 str. E2348/69 7060867 YP_002330992.1 CDS yhdH NC_011601.1 3672887 3673861 D oxidoreductase, Zn-dependent and NAD(P)-binding 3672887..3673861 Escherichia coli O127:H6 str. E2348/69 7065165 YP_002330993.1 CDS accB NC_011601.1 3674839 3675309 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3674839..3675309 Escherichia coli O127:H6 str. E2348/69 7064616 YP_002330994.1 CDS accC NC_011601.1 3675320 3676669 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3675320..3676669 Escherichia coli O127:H6 str. E2348/69 7062381 YP_002330995.1 CDS yhdT NC_011601.1 3676778 3677020 D hypothetical protein 3676778..3677020 Escherichia coli O127:H6 str. E2348/69 7062382 YP_002330996.1 CDS panF NC_011601.1 3677010 3678461 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3677010..3678461 Escherichia coli O127:H6 str. E2348/69 7064621 YP_002330997.1 CDS prmA NC_011601.1 3678473 3679354 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3678473..3679354 Escherichia coli O127:H6 str. E2348/69 7062910 YP_002330998.1 CDS dusB NC_011601.1 3679683 3680648 D tRNA-dihydrouridine synthase B 3679683..3680648 Escherichia coli O127:H6 str. E2348/69 7061293 YP_002330999.1 CDS fis NC_011601.1 3680674 3680970 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3680674..3680970 Escherichia coli O127:H6 str. E2348/69 7065072 YP_002331000.1 CDS yhdJ NC_011601.1 3681056 3681940 D methyltransferase 3681056..3681940 Escherichia coli O127:H6 str. E2348/69 7062128 YP_002331001.1 CDS yhdU NC_011601.1 3682024 3682203 D membrane protein 3682024..3682203 Escherichia coli O127:H6 str. E2348/69 7064617 YP_002331002.1 CDS envR NC_011601.1 3682206 3682868 R DNA-binding transcriptional regulator EnvR complement(3682206..3682868) Escherichia coli O127:H6 str. E2348/69 7064622 YP_002331003.1 CDS acrE NC_011601.1 3683267 3684424 D hypothetical protein 3683267..3684424 Escherichia coli O127:H6 str. E2348/69 7063860 YP_002331004.1 CDS acrF NC_011601.1 3684436 3687540 D multidrug efflux system protein 3684436..3687540 Escherichia coli O127:H6 str. E2348/69 7062399 YP_002331005.1 CDS yhdV NC_011601.1 3687793 3688014 D outer membrane protein 3687793..3688014 Escherichia coli O127:H6 str. E2348/69 7062400 YP_002331006.1 CDS yhdW NC_011601.1 3688445 3689470 D periplasmic binding transport protein; periplasmic-binding component of ABC superfamily 3688445..3689470 Escherichia coli O127:H6 str. E2348/69 7064623 YP_002331007.1 CDS yhdX NC_011601.1 3689538 3690719 D amino-acid transporter subunit 3689538..3690719 Escherichia coli O127:H6 str. E2348/69 7064624 YP_002331008.1 CDS yhdY NC_011601.1 3690729 3691832 D amino-acid transporter subunit 3690729..3691832 Escherichia coli O127:H6 str. E2348/69 7064625 YP_002331009.1 CDS yhdZ NC_011601.1 3691840 3692598 D amino-acid transporter subunit 3691840..3692598 Escherichia coli O127:H6 str. E2348/69 7064626 YP_002331010.1 CDS yrdA NC_011601.1 3698389 3698943 D hypothetical protein 3698389..3698943 Escherichia coli O127:H6 str. E2348/69 7064545 YP_002331011.1 CDS yrdB NC_011601.1 3698919 3699176 R hypothetical protein complement(3698919..3699176) Escherichia coli O127:H6 str. E2348/69 7063230 YP_002331012.1 CDS aroE NC_011601.1 3699173 3699991 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3699173..3699991) Escherichia coli O127:H6 str. E2348/69 7063231 YP_002331013.1 CDS rimN NC_011601.1 3699996 3700568 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3699996..3700568) Escherichia coli O127:H6 str. E2348/69 7061393 YP_002331014.1 CDS yrdD NC_011601.1 3700573 3701115 R DNA topoisomerase complement(3700573..3701115) Escherichia coli O127:H6 str. E2348/69 7060832 YP_002331015.1 CDS smg NC_011601.1 3701144 3701617 R hypothetical protein complement(3701144..3701617) Escherichia coli O127:H6 str. E2348/69 7063232 YP_002331016.1 CDS smf NC_011601.1 3701589 3702713 R DNA protecting protein DprA complement(3701589..3702713) Escherichia coli O127:H6 str. E2348/69 7062728 YP_002331017.1 CDS def NC_011601.1 3702843 3703352 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3702843..3703352 Escherichia coli O127:H6 str. E2348/69 7062727 YP_002331018.1 CDS fmt NC_011601.1 3703367 3704314 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3703367..3704314 Escherichia coli O127:H6 str. E2348/69 7065242 YP_002331019.1 CDS rsmB NC_011601.1 3704360 3705649 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3704360..3705649 Escherichia coli O127:H6 str. E2348/69 7061935 YP_002331020.1 CDS trkA NC_011601.1 3705671 3707047 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3705671..3707047 Escherichia coli O127:H6 str. E2348/69 7064555 YP_002331021.1 CDS mscL NC_011601.1 3707177 3707587 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3707177..3707587 Escherichia coli O127:H6 str. E2348/69 7062239 YP_002331022.1 CDS yhdL NC_011601.1 3707584 3707802 R hypothetical protein complement(3707584..3707802) Escherichia coli O127:H6 str. E2348/69 7060872 YP_002331023.1 CDS zntR NC_011601.1 3707858 3708283 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3707858..3708283) Escherichia coli O127:H6 str. E2348/69 7064618 YP_002331024.1 CDS yhdN NC_011601.1 3708294 3708662 R hypothetical protein complement(3708294..3708662) Escherichia coli O127:H6 str. E2348/69 7063261 YP_002331025.1 CDS rplQ NC_011601.1 3708769 3709152 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3708769..3709152) Escherichia coli O127:H6 str. E2348/69 7064619 YP_002331026.1 CDS rpoA NC_011601.1 3709193 3710182 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3709193..3710182) Escherichia coli O127:H6 str. E2348/69 7061844 YP_002331027.1 CDS rpsD NC_011601.1 3710208 3710828 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3710208..3710828) Escherichia coli O127:H6 str. E2348/69 7061863 YP_002331028.1 CDS rpsK NC_011601.1 3710862 3711251 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3710862..3711251) Escherichia coli O127:H6 str. E2348/69 7061876 YP_002331029.1 CDS rpsM NC_011601.1 3711268 3711624 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3711268..3711624) Escherichia coli O127:H6 str. E2348/69 7061883 YP_002331030.1 CDS rpmJ NC_011601.1 3711771 3711887 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3711771..3711887) Escherichia coli O127:H6 str. E2348/69 7061155 YP_002331031.1 CDS secY NC_011601.1 3711919 3713250 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3711919..3713250) Escherichia coli O127:H6 str. E2348/69 7061862 YP_002331032.1 CDS rplO NC_011601.1 3713258 3713692 R late assembly protein; 50S ribosomal protein L15 complement(3713258..3713692) Escherichia coli O127:H6 str. E2348/69 7065359 YP_002331033.1 CDS rpmD NC_011601.1 3713696 3713875 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3713696..3713875) Escherichia coli O127:H6 str. E2348/69 7061842 YP_002331034.1 CDS rpsE NC_011601.1 3713879 3714382 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3713879..3714382) Escherichia coli O127:H6 str. E2348/69 7061856 YP_002331035.1 CDS rplR NC_011601.1 3714397 3714750 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3714397..3714750) Escherichia coli O127:H6 str. E2348/69 7061877 YP_002331036.1 CDS rplF NC_011601.1 3714760 3715293 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3714760..3715293) Escherichia coli O127:H6 str. E2348/69 7061845 YP_002331037.1 CDS rpsH NC_011601.1 3715306 3715698 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3715306..3715698) Escherichia coli O127:H6 str. E2348/69 7061835 YP_002331038.1 CDS rpsN NC_011601.1 3715732 3716037 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3715732..3716037) Escherichia coli O127:H6 str. E2348/69 7061880 YP_002331039.1 CDS rplE NC_011601.1 3716052 3716591 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3716052..3716591) Escherichia coli O127:H6 str. E2348/69 7061886 YP_002331040.1 CDS rplX NC_011601.1 3716606 3716920 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3716606..3716920) Escherichia coli O127:H6 str. E2348/69 7061834 YP_002331041.1 CDS rplN NC_011601.1 3716931 3717302 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3716931..3717302) Escherichia coli O127:H6 str. E2348/69 7061851 YP_002331042.1 CDS rpsQ NC_011601.1 3717467 3717721 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3717467..3717721) Escherichia coli O127:H6 str. E2348/69 7061841 YP_002331043.1 CDS rpmC NC_011601.1 3717721 3717912 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3717721..3717912) Escherichia coli O127:H6 str. E2348/69 7061889 YP_002331044.1 CDS rplP NC_011601.1 3717912 3718322 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3717912..3718322) Escherichia coli O127:H6 str. E2348/69 7061855 YP_002331045.1 CDS rpsC NC_011601.1 3718335 3719036 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3718335..3719036) Escherichia coli O127:H6 str. E2348/69 7061843 YP_002331046.1 CDS rplV NC_011601.1 3719054 3719386 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3719054..3719386) Escherichia coli O127:H6 str. E2348/69 7061875 YP_002331047.1 CDS rpsS NC_011601.1 3719401 3719679 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3719401..3719679) Escherichia coli O127:H6 str. E2348/69 7061849 YP_002331048.1 CDS rplB NC_011601.1 3719696 3720517 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3719696..3720517) Escherichia coli O127:H6 str. E2348/69 7061891 YP_002331049.1 CDS rplW NC_011601.1 3720535 3720837 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3720535..3720837) Escherichia coli O127:H6 str. E2348/69 7061831 YP_002331050.1 CDS rplD NC_011601.1 3720834 3721439 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3720834..3721439) Escherichia coli O127:H6 str. E2348/69 7061850 YP_002331051.1 CDS rplC NC_011601.1 3721450 3722079 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3721450..3722079) Escherichia coli O127:H6 str. E2348/69 7061833 YP_002331052.1 CDS rpsJ NC_011601.1 3722112 3722423 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3722112..3722423) Escherichia coli O127:H6 str. E2348/69 7061832 YP_002331053.1 CDS E2348C_3585 NC_011601.1 3722802 3723269 D leader peptidase HopD 3722802..3723269 Escherichia coli O127:H6 str. E2348/69 7061882 YP_002331054.1 CDS bfr NC_011601.1 3723266 3723742 R iron storage protein; bacterioferritin complement(3723266..3723742) Escherichia coli O127:H6 str. E2348/69 7062642 YP_002331055.1 CDS bfd NC_011601.1 3723815 3724009 R bacterioferritin-associated ferredoxin complement(3723815..3724009) Escherichia coli O127:H6 str. E2348/69 7062511 YP_002331056.1 CDS tufA NC_011601.1 3724192 3725376 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3724192..3725376) Escherichia coli O127:H6 str. E2348/69 7062510 YP_002331057.1 CDS fusA NC_011601.1 3725447 3727561 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3725447..3727561) Escherichia coli O127:H6 str. E2348/69 7062279 YP_002331058.1 CDS rpsG NC_011601.1 3727658 3728128 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3727658..3728128) Escherichia coli O127:H6 str. E2348/69 7061604 YP_002331059.1 CDS rpsL NC_011601.1 3728225 3728599 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3728225..3728599) Escherichia coli O127:H6 str. E2348/69 7061879 YP_002331060.1 CDS yheL NC_011601.1 3728725 3729012 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3728725..3729012) Escherichia coli O127:H6 str. E2348/69 7061884 YP_002331061.1 CDS yheM NC_011601.1 3729020 3729379 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3729020..3729379) Escherichia coli O127:H6 str. E2348/69 7064628 YP_002331062.1 CDS yheN NC_011601.1 3729379 3729765 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3729379..3729765) Escherichia coli O127:H6 str. E2348/69 7064629 YP_002331063.1 CDS yheO NC_011601.1 3729765 3730487 R DNA-binding transcriptional regulator complement(3729765..3730487) Escherichia coli O127:H6 str. E2348/69 7064630 YP_002331064.1 CDS fkpA NC_011601.1 3730654 3731466 R rotamase; FKBP-type peptidylprolyl isomerase complement(3730654..3731466) Escherichia coli O127:H6 str. E2348/69 7064631 YP_002331065.1 CDS slyX NC_011601.1 3731687 3731905 D hypothetical protein 3731687..3731905 Escherichia coli O127:H6 str. E2348/69 7062134 YP_002331066.1 CDS slyD NC_011601.1 3731954 3732538 R rotamase; FKBP-type peptidylprolyl isomerase complement(3731954..3732538) Escherichia coli O127:H6 str. E2348/69 7062726 YP_002331067.1 CDS yheV NC_011601.1 3732633 3732833 R hypothetical protein complement(3732633..3732833) Escherichia coli O127:H6 str. E2348/69 7062725 YP_002331068.1 CDS kefB NC_011601.1 3732843 3734648 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3732843..3734648) Escherichia coli O127:H6 str. E2348/69 7064635 YP_002331069.1 CDS kefG NC_011601.1 3734648 3735202 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3734648..3735202) Escherichia coli O127:H6 str. E2348/69 7061500 YP_002331070.1 CDS yheS NC_011601.1 3735330 3737243 D ABC transporter ATP-binding protein 3735330..3737243 Escherichia coli O127:H6 str. E2348/69 7061503 YP_002331071.1 CDS yheT NC_011601.1 3737243 3738265 D hydrolase 3737243..3738265 Escherichia coli O127:H6 str. E2348/69 7064632 YP_002331072.1 CDS yheU NC_011601.1 3738259 3738477 D hypothetical protein 3738259..3738477 Escherichia coli O127:H6 str. E2348/69 7064633 YP_002331073.1 CDS prkB NC_011601.1 3738531 3739400 D phosphoribulokinase 3738531..3739400 Escherichia coli O127:H6 str. E2348/69 7064634 YP_002331074.1 CDS yhfA NC_011601.1 3739455 3739859 R hypothetical protein complement(3739455..3739859) Escherichia coli O127:H6 str. E2348/69 7061291 YP_002331075.1 CDS crp NC_011601.1 3740161 3740793 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3740161..3740793 Escherichia coli O127:H6 str. E2348/69 7064636 YP_002331076.1 CDS yhfK NC_011601.1 3740844 3742934 D hypothetical protein 3740844..3742934 Escherichia coli O127:H6 str. E2348/69 7062847 YP_002331077.1 CDS argD NC_011601.1 3743001 3744221 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase complement(3743001..3744221) Escherichia coli O127:H6 str. E2348/69 7064638 YP_002331078.1 CDS pabA NC_011601.1 3744307 3744870 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3744307..3744870) Escherichia coli O127:H6 str. E2348/69 7061368 YP_002331079.1 CDS fic NC_011601.1 3744902 3745504 R cell filamentation protein Fic complement(3744902..3745504) Escherichia coli O127:H6 str. E2348/69 7062900 YP_002331080.1 CDS yhfG NC_011601.1 3745494 3745661 R hypothetical protein complement(3745494..3745661) Escherichia coli O127:H6 str. E2348/69 7062117 YP_002331081.1 CDS ppiA NC_011601.1 3745766 3746338 R peptidyl-prolyl cis-trans isomerase A complement(3745766..3746338) Escherichia coli O127:H6 str. E2348/69 7064637 YP_002331082.1 CDS tsgA NC_011601.1 3746609 3747790 D hypothetical protein 3746609..3747790 Escherichia coli O127:H6 str. E2348/69 7061270 YP_002331083.1 CDS nirB NC_011601.1 3748052 3750595 D nitrite reductase, large subunit, NAD(P)H-binding 3748052..3750595 Escherichia coli O127:H6 str. E2348/69 7062271 YP_002331084.1 CDS nirD NC_011601.1 3750592 3750918 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3750592..3750918 Escherichia coli O127:H6 str. E2348/69 7065397 YP_002331085.1 CDS nirC NC_011601.1 3751044 3751850 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3751044..3751850 Escherichia coli O127:H6 str. E2348/69 7065399 YP_002331086.1 CDS cysG NC_011601.1 3751869 3753242 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3751869..3753242 Escherichia coli O127:H6 str. E2348/69 7065398 YP_002331087.1 CDS yhfL NC_011601.1 3753494 3753661 D hypothetical protein 3753494..3753661 Escherichia coli O127:H6 str. E2348/69 7065198 YP_002331088.1 CDS yhfS NC_011601.1 3753768 3754853 R hypothetical protein complement(3753768..3754853) Escherichia coli O127:H6 str. E2348/69 7064639 YP_002331089.1 CDS yhfT NC_011601.1 3754865 3756169 R hypothetical protein complement(3754865..3756169) Escherichia coli O127:H6 str. E2348/69 7064640 YP_002331090.1 CDS yhfU NC_011601.1 3756181 3756534 R hypothetical protein complement(3756181..3756534) Escherichia coli O127:H6 str. E2348/69 7064641 YP_002331091.1 CDS php NC_011601.1 3756545 3757423 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3756545..3757423) Escherichia coli O127:H6 str. E2348/69 7064642 YP_002331092.1 CDS yhfW NC_011601.1 3757420 3758646 R mutase complement(3757420..3758646) Escherichia coli O127:H6 str. E2348/69 7060750 YP_002331093.1 CDS yhfX NC_011601.1 3758647 3759810 R amino acid racemase complement(3758647..3759810) Escherichia coli O127:H6 str. E2348/69 7064643 YP_002331094.1 CDS yhfY NC_011601.1 3759894 3760256 R hypothetical protein complement(3759894..3760256) Escherichia coli O127:H6 str. E2348/69 7064644 YP_002331095.1 CDS yhfZ NC_011601.1 3760273 3761178 R hypothetical protein complement(3760273..3761178) Escherichia coli O127:H6 str. E2348/69 7064645 YP_002331096.1 CDS trpS NC_011601.1 3761338 3762342 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3761338..3762342) Escherichia coli O127:H6 str. E2348/69 7064646 YP_002331097.1 CDS gph NC_011601.1 3762335 3763093 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3762335..3763093) Escherichia coli O127:H6 str. E2348/69 7062261 YP_002331098.1 CDS rpe NC_011601.1 3763086 3763763 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3763086..3763763) Escherichia coli O127:H6 str. E2348/69 7064233 YP_002331099.1 CDS dam NC_011601.1 3763781 3764617 R DNA adenine methylase complement(3763781..3764617) Escherichia coli O127:H6 str. E2348/69 7061825 YP_002331100.1 CDS damX NC_011601.1 3764724 3766010 R hypothetical protein complement(3764724..3766010) Escherichia coli O127:H6 str. E2348/69 7065218 YP_002331101.1 CDS aroB NC_011601.1 3766102 3767190 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3766102..3767190) Escherichia coli O127:H6 str. E2348/69 7065219 YP_002331102.1 CDS aroK NC_011601.1 3767247 3767768 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3767247..3767768) Escherichia coli O127:H6 str. E2348/69 7061390 YP_002331103.1 CDS hofQ NC_011601.1 3768169 3769407 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3768169..3769407) Escherichia coli O127:H6 str. E2348/69 7061397 YP_002331104.1 CDS hofO NC_011601.1 3769712 3770152 R membrane protein complement(3769712..3770152) Escherichia coli O127:H6 str. E2348/69 7062166 YP_002331105.1 CDS hofN NC_011601.1 3770136 3770675 R fimbrial assembly protein complement(3770136..3770675) Escherichia coli O127:H6 str. E2348/69 7062165 YP_002331106.1 CDS hofM NC_011601.1 3770675 3771454 R pilus assembly protein complement(3770675..3771454) Escherichia coli O127:H6 str. E2348/69 7062164 YP_002331107.1 CDS mrcA NC_011601.1 3771574 3774126 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3771574..3774126 Escherichia coli O127:H6 str. E2348/69 7062163 YP_002331108.1 CDS nudE NC_011601.1 3774292 3774852 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3774292..3774852) Escherichia coli O127:H6 str. E2348/69 7060863 YP_002331109.1 CDS yrfF NC_011601.1 3775172 3777307 D hypothetical protein 3775172..3777307 Escherichia coli O127:H6 str. E2348/69 7065429 YP_002331110.1 CDS yrfG NC_011601.1 3777372 3778040 D hydrolase 3777372..3778040 Escherichia coli O127:H6 str. E2348/69 7063233 YP_002331111.1 CDS hslR NC_011601.1 3778051 3778452 D ribosome-associated heat shock protein Hsp15 3778051..3778452 Escherichia coli O127:H6 str. E2348/69 7063234 YP_002331112.1 CDS hslO NC_011601.1 3778477 3779355 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3778477..3779355 Escherichia coli O127:H6 str. E2348/69 7062184 YP_002331113.1 CDS yhgE NC_011601.1 3779418 3781142 R hypothetical protein complement(3779418..3781142) Escherichia coli O127:H6 str. E2348/69 7062183 YP_002331114.1 CDS pck NC_011601.1 3781521 3783143 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3781521..3783143 Escherichia coli O127:H6 str. E2348/69 7064648 YP_002331115.1 CDS E2348C_3648 NC_011601.1 3783628 3783924 D hypothetical protein 3783628..3783924 Escherichia coli O127:H6 str. E2348/69 7062915 YP_002331116.1 CDS envZ NC_011601.1 3783956 3785308 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3783956..3785308) Escherichia coli O127:H6 str. E2348/69 7062643 YP_002331117.1 CDS ompR NC_011601.1 3785305 3786024 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3785305..3786024) Escherichia coli O127:H6 str. E2348/69 7063861 YP_002331118.1 CDS greB NC_011601.1 3786252 3786728 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3786252..3786728 Escherichia coli O127:H6 str. E2348/69 7062878 YP_002331119.1 CDS yhgF NC_011601.1 3786825 3789146 D transcriptional accessory protein 3786825..3789146 Escherichia coli O127:H6 str. E2348/69 7064240 YP_002331120.1 CDS feoA NC_011601.1 3789584 3789811 D ferrous iron transport protein A 3789584..3789811 Escherichia coli O127:H6 str. E2348/69 7064649 YP_002331121.1 CDS feoB NC_011601.1 3789828 3792149 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3789828..3792149 Escherichia coli O127:H6 str. E2348/69 7062097 YP_002331122.1 CDS feoC NC_011601.1 3792149 3792385 D DNA-binding transcriptional regulator 3792149..3792385 Escherichia coli O127:H6 str. E2348/69 7062098 YP_002331123.1 CDS yhgA NC_011601.1 3792588 3793469 D hypothetical protein 3792588..3793469 Escherichia coli O127:H6 str. E2348/69 7062099 YP_002331124.1 CDS bioH NC_011601.1 3793689 3794459 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3793689..3794459) Escherichia coli O127:H6 str. E2348/69 7064647 YP_002331125.1 CDS gntX NC_011601.1 3794497 3795180 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3794497..3795180 Escherichia coli O127:H6 str. E2348/69 7062525 YP_002331126.1 CDS gntY NC_011601.1 3795239 3795814 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3795239..3795814 Escherichia coli O127:H6 str. E2348/69 7064230 YP_002331127.1 CDS gntT NC_011601.1 3796178 3797494 D gluconate transporter, high-affinity GNT Isystem 3796178..3797494 Escherichia coli O127:H6 str. E2348/69 7064231 YP_002331128.1 CDS malQ NC_011601.1 3797605 3799689 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3797605..3799689) Escherichia coli O127:H6 str. E2348/69 7061738 YP_002331129.1 CDS malP NC_011601.1 3799699 3802092 R maltodextrin phosphorylase complement(3799699..3802092) Escherichia coli O127:H6 str. E2348/69 7065277 YP_002331130.1 CDS malT NC_011601.1 3802714 3805419 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3802714..3805419 Escherichia coli O127:H6 str. E2348/69 7065276 YP_002331131.1 CDS rtcA NC_011601.1 3805462 3806478 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3805462..3806478) Escherichia coli O127:H6 str. E2348/69 7065279 YP_002331132.1 CDS rtcB NC_011601.1 3806482 3807708 R hypothetical protein complement(3806482..3807708) Escherichia coli O127:H6 str. E2348/69 7064573 YP_002331133.1 CDS rtcR NC_011601.1 3807897 3809495 D sigma 54-dependent transcriptional regulator of rtcBA expression 3807897..3809495 Escherichia coli O127:H6 str. E2348/69 7064574 YP_002331134.1 CDS glpR NC_011601.1 3809477 3810235 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3809477..3810235) Escherichia coli O127:H6 str. E2348/69 7064575 YP_002331135.1 CDS glpG NC_011601.1 3810252 3811082 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3810252..3811082) Escherichia coli O127:H6 str. E2348/69 7061701 YP_002331136.1 CDS glpE NC_011601.1 3811127 3811453 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3811127..3811453) Escherichia coli O127:H6 str. E2348/69 7061698 YP_002331137.1 CDS glpD NC_011601.1 3811643 3813148 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3811643..3813148 Escherichia coli O127:H6 str. E2348/69 7061696 YP_002331138.1 CDS E2348C_3671 NC_011601.1 3813202 3813807 R hypothetical protein complement(3813202..3813807) Escherichia coli O127:H6 str. E2348/69 7061695 YP_002331139.1 CDS E2348C_3672 NC_011601.1 3813810 3814577 R hypothetical protein complement(3813810..3814577) Escherichia coli O127:H6 str. E2348/69 7062644 YP_002331140.1 CDS glgP NC_011601.1 3816314 3818761 R glycogen phosphorylase complement(3816314..3818761) Escherichia coli O127:H6 str. E2348/69 7062646 YP_002331141.1 CDS glgA NC_011601.1 3818780 3820213 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3818780..3820213) Escherichia coli O127:H6 str. E2348/69 7061669 YP_002331142.1 CDS glgC NC_011601.1 3820213 3821508 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3820213..3821508) Escherichia coli O127:H6 str. E2348/69 7061666 YP_002331143.1 CDS glgX NC_011601.1 3821526 3823499 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3821526..3823499) Escherichia coli O127:H6 str. E2348/69 7061668 YP_002331144.1 CDS glgB NC_011601.1 3823496 3825682 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3823496..3825682) Escherichia coli O127:H6 str. E2348/69 7061671 YP_002331145.1 CDS asd NC_011601.1 3825955 3827058 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3825955..3827058) Escherichia coli O127:H6 str. E2348/69 7061667 YP_002331146.1 CDS yhgN NC_011601.1 3827250 3827843 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3827250..3827843 Escherichia coli O127:H6 str. E2348/69 7061407 YP_002331147.1 CDS gntU NC_011601.1 3827900 3829240 R low affinity gluconate transporter complement(3827900..3829240) Escherichia coli O127:H6 str. E2348/69 7064650 YP_002331148.1 CDS gntK NC_011601.1 3829244 3829771 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3829244..3829771) Escherichia coli O127:H6 str. E2348/69 7062055 YP_002331149.1 CDS gntR NC_011601.1 3829910 3830905 R DNA-binding transcriptional repressor complement(3829910..3830905) Escherichia coli O127:H6 str. E2348/69 7061736 YP_002331150.1 CDS yhhW NC_011601.1 3830998 3831693 R hypothetical protein complement(3830998..3831693) Escherichia coli O127:H6 str. E2348/69 7061737 YP_002331151.1 CDS yhhX NC_011601.1 3831816 3832853 R dehydrogenase complement(3831816..3832853) Escherichia coli O127:H6 str. E2348/69 7064660 YP_002331152.1 CDS yhhY NC_011601.1 3833187 3833675 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3833187..3833675 Escherichia coli O127:H6 str. E2348/69 7060817 YP_002331153.1 CDS ggt NC_011601.1 3833736 3835469 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3833736..3835469) Escherichia coli O127:H6 str. E2348/69 7064662 YP_002331154.1 CDS yhhA NC_011601.1 3835589 3836029 D hypothetical protein 3835589..3836029 Escherichia coli O127:H6 str. E2348/69 7061653 YP_002331155.1 CDS ugpQ NC_011601.1 3836016 3836759 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3836016..3836759) Escherichia coli O127:H6 str. E2348/69 7064651 YP_002331156.1 CDS ugpC NC_011601.1 3836756 3837826 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3836756..3837826) Escherichia coli O127:H6 str. E2348/69 7062307 YP_002331157.1 CDS ugpE NC_011601.1 3837828 3838673 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3837828..3838673) Escherichia coli O127:H6 str. E2348/69 7062305 YP_002331158.1 CDS ugpA NC_011601.1 3838670 3839557 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3838670..3839557) Escherichia coli O127:H6 str. E2348/69 7062306 YP_002331159.1 CDS ugpB NC_011601.1 3839655 3840971 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3839655..3840971) Escherichia coli O127:H6 str. E2348/69 7062303 YP_002331160.1 CDS livF NC_011601.1 3841368 3842081 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3841368..3842081) Escherichia coli O127:H6 str. E2348/69 7062304 YP_002331161.1 CDS livG NC_011601.1 3842083 3842850 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3842083..3842850) Escherichia coli O127:H6 str. E2348/69 7061544 YP_002331162.1 CDS livM NC_011601.1 3842847 3844124 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3842847..3844124) Escherichia coli O127:H6 str. E2348/69 7061545 YP_002331163.1 CDS livH NC_011601.1 3844121 3845047 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3844121..3845047) Escherichia coli O127:H6 str. E2348/69 7061549 YP_002331164.1 CDS livK NC_011601.1 3845095 3846204 R leucine transporter subunit complement(3845095..3846204) Escherichia coli O127:H6 str. E2348/69 7061546 YP_002331165.1 CDS yhhK NC_011601.1 3846628 3847011 D hypothetical protein 3846628..3847011 Escherichia coli O127:H6 str. E2348/69 7061548 YP_002331166.1 CDS livJ NC_011601.1 3847199 3848302 R leucine/isoleucine/valine transporter subunit complement(3847199..3848302) Escherichia coli O127:H6 str. E2348/69 7064653 YP_002331167.1 CDS rpoH NC_011601.1 3848573 3849427 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3848573..3849427) Escherichia coli O127:H6 str. E2348/69 7061547 YP_002331168.1 CDS ftsX NC_011601.1 3849672 3850730 R ABC transporter, membrane protein; cell division protein FtsX complement(3849672..3850730) Escherichia coli O127:H6 str. E2348/69 7061868 YP_002331169.1 CDS ftsE NC_011601.1 3850723 3851391 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3850723..3851391) Escherichia coli O127:H6 str. E2348/69 7061590 YP_002331170.1 CDS ftsY NC_011601.1 3851394 3852890 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3851394..3852890) Escherichia coli O127:H6 str. E2348/69 7061583 YP_002331171.1 CDS rsmD NC_011601.1 3853040 3853636 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3853040..3853636 Escherichia coli O127:H6 str. E2348/69 7061591 YP_002331172.1 CDS yhhL NC_011601.1 3853626 3853895 D hypothetical protein 3853626..3853895 Escherichia coli O127:H6 str. E2348/69 7064557 YP_002331173.1 CDS yhhM NC_011601.1 3853898 3854257 R hypothetical protein complement(3853898..3854257) Escherichia coli O127:H6 str. E2348/69 7064654 YP_002331174.1 CDS yhhN NC_011601.1 3854398 3855024 D hypothetical protein 3854398..3855024 Escherichia coli O127:H6 str. E2348/69 7064655 YP_002331175.1 CDS zntA NC_011601.1 3855098 3857296 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3855098..3857296 Escherichia coli O127:H6 str. E2348/69 7064656 YP_002331176.1 CDS E2348C_3710 NC_011601.1 3857676 3859049 D transposase of ISEc13 3857676..3859049 Escherichia coli O127:H6 str. E2348/69 7061128 YP_002331177.1 CDS sirA NC_011601.1 3859124 3859369 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3859124..3859369) Escherichia coli O127:H6 str. E2348/69 7062647 YP_002331178.1 CDS yhhQ NC_011601.1 3859590 3860255 D hypothetical protein 3859590..3860255 Escherichia coli O127:H6 str. E2348/69 7062717 YP_002331179.1 CDS dcrB NC_011601.1 3860286 3860885 D hypothetical protein 3860286..3860885 Escherichia coli O127:H6 str. E2348/69 7064657 YP_002331180.1 CDS yhhS NC_011601.1 3860889 3862106 R major facilitator superfamily transporter complement(3860889..3862106) Escherichia coli O127:H6 str. E2348/69 7065229 YP_002331181.1 CDS yhhT NC_011601.1 3862238 3863287 D hypothetical protein 3862238..3863287 Escherichia coli O127:H6 str. E2348/69 7064658 YP_002331182.1 CDS acpT NC_011601.1 3863342 3863929 D holo-(acyl carrier protein) synthase 2 3863342..3863929 Escherichia coli O127:H6 str. E2348/69 7064659 YP_002331183.1 CDS nikA NC_011601.1 3864040 3865614 D nickel transporter subunit 3864040..3865614 Escherichia coli O127:H6 str. E2348/69 7062395 YP_002331184.1 CDS nikB NC_011601.1 3865614 3866558 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3865614..3866558 Escherichia coli O127:H6 str. E2348/69 7065391 YP_002331185.1 CDS nikC NC_011601.1 3866555 3867388 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3866555..3867388 Escherichia coli O127:H6 str. E2348/69 7065392 YP_002331186.1 CDS nikD NC_011601.1 3867388 3868152 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3867388..3868152 Escherichia coli O127:H6 str. E2348/69 7065393 YP_002331187.1 CDS nikE NC_011601.1 3868149 3868955 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3868149..3868955 Escherichia coli O127:H6 str. E2348/69 7065394 YP_002331188.1 CDS nikR NC_011601.1 3868961 3869362 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3868961..3869362 Escherichia coli O127:H6 str. E2348/69 7065395 YP_002331189.1 CDS E2348C_3723 NC_011601.1 3869482 3869841 R HicB-like protein complement(3869482..3869841) Escherichia coli O127:H6 str. E2348/69 7065396 YP_002331190.1 CDS E2348C_3724 NC_011601.1 3869838 3870113 R HicA-like protein complement(3869838..3870113) Escherichia coli O127:H6 str. E2348/69 7062648 YP_002331191.1 CDS yhhJ NC_011601.1 3870186 3871310 R transporter subunit: membrane component of ABC superfamily complement(3870186..3871310) Escherichia coli O127:H6 str. E2348/69 7062649 YP_002331192.1 CDS rbbA NC_011601.1 3871310 3874045 R fused ribosome-associated ATPase RbbA: ATP-binding protein/ATP-binding protein/ membrane protein complement(3871310..3874045) Escherichia coli O127:H6 str. E2348/69 7064652 YP_002331193.1 CDS yhiI NC_011601.1 3874042 3875109 R HlyD family secretion protein complement(3874042..3875109) Escherichia coli O127:H6 str. E2348/69 7063951 YP_002331194.1 CDS yhiM NC_011601.1 3875843 3876895 D hypothetical protein 3875843..3876895 Escherichia coli O127:H6 str. E2348/69 7064665 YP_002331195.1 CDS yhiN NC_011601.1 3876982 3878175 R oxidoreductase with FAD/NAD(P)-binding domain complement(3876982..3878175) Escherichia coli O127:H6 str. E2348/69 7064666 YP_002331196.1 CDS pitA NC_011601.1 3878407 3879906 D phosphate transporter, low-affinity 3878407..3879906 Escherichia coli O127:H6 str. E2348/69 7064667 YP_002331197.1 CDS uspB NC_011601.1 3879977 3880312 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3879977..3880312) Escherichia coli O127:H6 str. E2348/69 7060752 YP_002331198.1 CDS uspA NC_011601.1 3880703 3881137 D universal stress global response regulator 3880703..3881137 Escherichia coli O127:H6 str. E2348/69 7062333 YP_002331199.1 CDS yhiP NC_011601.1 3881454 3882923 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3881454..3882923 Escherichia coli O127:H6 str. E2348/69 7062332 YP_002331200.1 CDS yhiQ NC_011601.1 3882972 3883724 R SAM-dependent methyltransferase; methyltransferase complement(3882972..3883724) Escherichia coli O127:H6 str. E2348/69 7064668 YP_002331201.1 CDS prlC NC_011601.1 3883732 3885774 R oligopeptidase A complement(3883732..3885774) Escherichia coli O127:H6 str. E2348/69 7064669 YP_002331202.1 CDS yhiR NC_011601.1 3885977 3886819 D DNA (exogenous) processing protein 3885977..3886819 Escherichia coli O127:H6 str. E2348/69 7061292 YP_002331203.1 CDS gor NC_011601.1 3886891 3888243 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3886891..3888243 Escherichia coli O127:H6 str. E2348/69 7064670 YP_002331204.1 CDS dinQ NC_011601.1 3888297 3888425 R damage inducible protein complement(3888297..3888425) Escherichia coli O127:H6 str. E2348/69 7064232 YP_002331205.1 CDS arsC NC_011601.1 3888914 3889339 D arsenate reductase 3888914..3889339 Escherichia coli O127:H6 str. E2348/69 7065033 YP_002331206.1 CDS slp NC_011601.1 3890523 3891089 D outer membrane lipoprotein 3890523..3891089 Escherichia coli O127:H6 str. E2348/69 7061401 YP_002331207.1 CDS yhiF NC_011601.1 3891242 3891772 D DNA-binding transcriptional regulator 3891242..3891772 Escherichia coli O127:H6 str. E2348/69 7062721 YP_002331208.1 CDS chuS NC_011601.1 3891829 3892857 R heme/hemoglobin transport protein complement(3891829..3892857) Escherichia coli O127:H6 str. E2348/69 7064664 YP_002331209.1 CDS chuA NC_011601.1 3892906 3894888 R outer membrane heme/hemoglobin receptor complement(3892906..3894888) Escherichia coli O127:H6 str. E2348/69 7062790 YP_002331210.1 CDS chuT NC_011601.1 3895572 3896486 D hemin binding protein 3895572..3896486 Escherichia coli O127:H6 str. E2348/69 7062789 YP_002331211.1 CDS chuW NC_011601.1 3896506 3897843 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3896506..3897843 Escherichia coli O127:H6 str. E2348/69 7062791 YP_002331212.1 CDS chuX NC_011601.1 3897856 3898350 D ShuX-like protein 3897856..3898350 Escherichia coli O127:H6 str. E2348/69 7062793 YP_002331213.1 CDS chuY NC_011601.1 3898350 3898973 D ShuY-like protein 3898350..3898973 Escherichia coli O127:H6 str. E2348/69 7062794 YP_002331214.1 CDS chuU NC_011601.1 3899058 3900014 D hemin permease 3899058..3900014 Escherichia coli O127:H6 str. E2348/69 7062795 YP_002331215.1 CDS hmuV NC_011601.1 3900011 3900781 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3900011..3900781 Escherichia coli O127:H6 str. E2348/69 7062792 YP_002331216.1 CDS yhiD NC_011601.1 3900833 3901480 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(3900833..3901480) Escherichia coli O127:H6 str. E2348/69 7062650 YP_002331217.1 CDS hdeB NC_011601.1 3901544 3901882 R acid-resistance protein complement(3901544..3901882) Escherichia coli O127:H6 str. E2348/69 7064663 YP_002331218.1 CDS hdeA NC_011601.1 3901986 3902318 R inactive form; acid-resistance protein complement(3901986..3902318) Escherichia coli O127:H6 str. E2348/69 7064286 YP_002331219.1 CDS hdeD NC_011601.1 3902573 3903145 D acid-resistance membrane protein 3902573..3903145 Escherichia coli O127:H6 str. E2348/69 7064285 YP_002331220.1 CDS gadE NC_011601.1 3903944 3904471 D DNA-binding transcriptional activator 3903944..3904471 Escherichia coli O127:H6 str. E2348/69 7064287 YP_002331221.1 CDS mdtE NC_011601.1 3904810 3905967 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3904810..3905967 Escherichia coli O127:H6 str. E2348/69 7061612 YP_002331222.1 CDS mdtF NC_011601.1 3905992 3909105 D multidrug transporter, RpoS-dependent 3905992..3909105 Escherichia coli O127:H6 str. E2348/69 7065310 YP_002331223.1 CDS gadW NC_011601.1 3909468 3910196 R DNA-binding transcriptional activator complement(3909468..3910196) Escherichia coli O127:H6 str. E2348/69 7065311 YP_002331224.1 CDS gadX NC_011601.1 3910565 3911389 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3910565..3911389) Escherichia coli O127:H6 str. E2348/69 7061615 YP_002331225.1 CDS gadA NC_011601.1 3911757 3913157 R glutamate decarboxylase complement(3911757..3913157) Escherichia coli O127:H6 str. E2348/69 7061614 YP_002331226.1 CDS yhjA NC_011601.1 3913368 3914765 R cytochrome C peroxidase complement(3913368..3914765) Escherichia coli O127:H6 str. E2348/69 7061609 YP_002331227.1 CDS treF NC_011601.1 3915170 3916819 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3915170..3916819 Escherichia coli O127:H6 str. E2348/69 7064671 YP_002331228.1 CDS yhjB NC_011601.1 3916870 3917472 R DNA-binding response regulator in two-component regulatory system complement(3916870..3917472) Escherichia coli O127:H6 str. E2348/69 7062236 YP_002331229.1 CDS yhjC NC_011601.1 3917920 3918891 D DNA-binding transcriptional regulator 3917920..3918891 Escherichia coli O127:H6 str. E2348/69 7064672 YP_002331230.1 CDS yhjD NC_011601.1 3918940 3919953 D hypothetical protein 3918940..3919953 Escherichia coli O127:H6 str. E2348/69 7064673 YP_002331231.1 CDS yhjE NC_011601.1 3920346 3921668 D transporter 3920346..3921668 Escherichia coli O127:H6 str. E2348/69 7064674 YP_002331232.1 CDS yhjG NC_011601.1 3921709 3923784 R outer membrane biogenesis protein complement(3921709..3923784) Escherichia coli O127:H6 str. E2348/69 7064675 YP_002331233.1 CDS yhjH NC_011601.1 3923839 3924606 R in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase complement(3923839..3924606) Escherichia coli O127:H6 str. E2348/69 7064676 YP_002331234.1 CDS kdgK NC_011601.1 3924838 3925767 D ketodeoxygluconokinase 3924838..3925767 Escherichia coli O127:H6 str. E2348/69 7064677 YP_002331235.1 CDS yhjJ NC_011601.1 3925863 3927359 R zinc-dependent peptidase complement(3925863..3927359) Escherichia coli O127:H6 str. E2348/69 7063569 YP_002331236.1 CDS dctA NC_011601.1 3927580 3928866 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3927580..3928866) Escherichia coli O127:H6 str. E2348/69 7064678 YP_002331237.1 CDS yhjK NC_011601.1 3929049 3931004 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase complement(3929049..3931004) Escherichia coli O127:H6 str. E2348/69 7065230 YP_002331238.1 CDS bcsC NC_011601.1 3931119 3934592 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3931119..3934592) Escherichia coli O127:H6 str. E2348/69 7064679 YP_002331239.1 CDS bcsZ NC_011601.1 3934574 3935680 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3934574..3935680) Escherichia coli O127:H6 str. E2348/69 7062501 YP_002331240.1 CDS bcsB NC_011601.1 3935687 3938026 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3935687..3938026) Escherichia coli O127:H6 str. E2348/69 7062504 YP_002331241.1 CDS bcsA NC_011601.1 3938037 3940655 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3938037..3940655) Escherichia coli O127:H6 str. E2348/69 7062500 YP_002331242.1 CDS yhjQ NC_011601.1 3940652 3941404 R cell division protein complement(3940652..3941404) Escherichia coli O127:H6 str. E2348/69 7062499 YP_002331243.1 CDS yhjR NC_011601.1 3941416 3941604 R hypothetical protein complement(3941416..3941604) Escherichia coli O127:H6 str. E2348/69 7064680 YP_002331244.1 CDS bcsE NC_011601.1 3941877 3943448 D hypothetical protein 3941877..3943448 Escherichia coli O127:H6 str. E2348/69 7064681 YP_002331245.1 CDS bcsF NC_011601.1 3943445 3943636 D hypothetical protein 3943445..3943636 Escherichia coli O127:H6 str. E2348/69 7062502 YP_002331246.1 CDS bcsG NC_011601.1 3943633 3945312 D hypothetical protein 3943633..3945312 Escherichia coli O127:H6 str. E2348/69 7062503 YP_002331247.1 CDS E2348C_3781 NC_011601.1 3945427 3945885 R transposase of IS200C complement(3945427..3945885) Escherichia coli O127:H6 str. E2348/69 7061129 YP_002331248.1 CDS ldrD1 NC_011601.1 3946109 3946216 R small toxic polypeptide ldrD 1 complement(3946109..3946216) Escherichia coli O127:H6 str. E2348/69 7062651 YP_002331249.1 CDS ldrD2 NC_011601.1 3946592 3946699 R small toxic polypeptide ldrD 2 complement(3946592..3946699) Escherichia coli O127:H6 str. E2348/69 7063972 YP_002331250.1 CDS yhjV NC_011601.1 3947175 3948446 D transporter 3947175..3948446 Escherichia coli O127:H6 str. E2348/69 7063973 YP_002331251.1 CDS E2348C_3785 NC_011601.1 3948463 3949470 R hypothetical protein complement(3948463..3949470) Escherichia coli O127:H6 str. E2348/69 7064682 YP_002331252.1 CDS E2348C_3786 NC_011601.1 3949470 3949781 R hypothetical protein complement(3949470..3949781) Escherichia coli O127:H6 str. E2348/69 7062652 YP_002331253.1 CDS E2348C_3787 NC_011601.1 3949766 3950089 R transcriptional regulator, XRE family complement(3949766..3950089) Escherichia coli O127:H6 str. E2348/69 7062653 YP_002331254.1 CDS dppF NC_011601.1 3950314 3951327 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(3950314..3951327) Escherichia coli O127:H6 str. E2348/69 7062654 YP_002331255.1 CDS dppD NC_011601.1 3951324 3952307 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(3951324..3952307) Escherichia coli O127:H6 str. E2348/69 7065060 YP_002331256.1 CDS dppC NC_011601.1 3952318 3953220 R dipeptide transporter complement(3952318..3953220) Escherichia coli O127:H6 str. E2348/69 7065059 YP_002331257.1 CDS dppB NC_011601.1 3953230 3954249 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(3953230..3954249) Escherichia coli O127:H6 str. E2348/69 7065058 YP_002331258.1 CDS dppA NC_011601.1 3954557 3956164 R dipeptide transporter complement(3954557..3956164) Escherichia coli O127:H6 str. E2348/69 7065057 YP_002331259.1 CDS eptB NC_011601.1 3957076 3958767 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(3957076..3958767) Escherichia coli O127:H6 str. E2348/69 7061299 YP_002331260.1 CDS lpfE NC_011601.1 3959031 3959561 R fimbrial protein complement(3959031..3959561) Escherichia coli O127:H6 str. E2348/69 7063864 YP_002331261.1 CDS lpfD NC_011601.1 3959567 3960622 R fimbrial protein complement(3959567..3960622) Escherichia coli O127:H6 str. E2348/69 7061566 YP_002331262.1 CDS lpfC NC_011601.1 3960638 3963217 R fimbrial usher protein complement(3960638..3963217) Escherichia coli O127:H6 str. E2348/69 7061565 YP_002331263.1 CDS lpfB NC_011601.1 3963241 3963894 R fimbrial chaperone complement(3963241..3963894) Escherichia coli O127:H6 str. E2348/69 7061564 YP_002331264.1 CDS lpfA NC_011601.1 3963994 3964518 R fimbrial major protein complement(3963994..3964518) Escherichia coli O127:H6 str. E2348/69 7061563 YP_002331265.1 CDS yhjX NC_011601.1 3964865 3966067 R transporter complement(3964865..3966067) Escherichia coli O127:H6 str. E2348/69 7061562 YP_002331266.1 CDS tag NC_011601.1 3967156 3967719 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3967156..3967719 Escherichia coli O127:H6 str. E2348/69 7061499 YP_002331267.1 CDS yiaC NC_011601.1 3967716 3968156 D hypothetical protein 3967716..3968156 Escherichia coli O127:H6 str. E2348/69 7061748 YP_002331268.1 CDS yiaD NC_011601.1 3970429 3971088 D outer membrane lipoprotein 3970429..3971088 Escherichia coli O127:H6 str. E2348/69 7062527 YP_002331269.1 CDS ghrB NC_011601.1 3971192 3972166 D 2-keto-D-gluconate reductase (glyoxalatereductase) (2-ketoaldonate reductase) 3971192..3972166 Escherichia coli O127:H6 str. E2348/69 7064767 YP_002331270.1 CDS yiaF NC_011601.1 3972216 3972926 R hypothetical protein complement(3972216..3972926) Escherichia coli O127:H6 str. E2348/69 7061655 YP_002331271.1 CDS yiaG NC_011601.1 3973360 3973650 D transcriptional regulator 3973360..3973650 Escherichia coli O127:H6 str. E2348/69 7064768 YP_002331272.1 CDS cspA NC_011601.1 3973931 3974143 D major cold shock protein 3973931..3974143 Escherichia coli O127:H6 str. E2348/69 7064769 YP_002331273.1 CDS hokA NC_011601.1 3974331 3974483 R small toxic polypeptide complement(3974331..3974483) Escherichia coli O127:H6 str. E2348/69 7062860 YP_002331274.1 CDS glyS NC_011601.1 3974806 3976875 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(3974806..3976875) Escherichia coli O127:H6 str. E2348/69 7062168 YP_002331275.1 CDS glyQ NC_011601.1 3976885 3977796 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(3976885..3977796) Escherichia coli O127:H6 str. E2348/69 7061722 YP_002331276.1 CDS ysaB NC_011601.1 3977891 3978190 R hypothetical protein complement(3977891..3978190) Escherichia coli O127:H6 str. E2348/69 7061721 YP_002331277.1 CDS wecH NC_011601.1 3978365 3979360 D hypothetical protein 3978365..3979360 Escherichia coli O127:H6 str. E2348/69 7063236 YP_002331278.1 CDS yiaA NC_011601.1 3979401 3979838 R hypothetical protein complement(3979401..3979838) Escherichia coli O127:H6 str. E2348/69 7064844 YP_002331279.1 CDS yiaB NC_011601.1 3979884 3980225 R hypothetical protein complement(3979884..3980225) Escherichia coli O127:H6 str. E2348/69 7064764 YP_002331280.1 CDS xylB NC_011601.1 3980394 3981848 R xylulokinase complement(3980394..3981848) Escherichia coli O127:H6 str. E2348/69 7064765 YP_002331281.1 CDS xylA NC_011601.1 3981920 3983242 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(3981920..3983242) Escherichia coli O127:H6 str. E2348/69 7064870 YP_002331282.1 CDS xylF NC_011601.1 3983608 3984600 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3983608..3984600 Escherichia coli O127:H6 str. E2348/69 7064869 YP_002331283.1 CDS xylG NC_011601.1 3984678 3986219 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3984678..3986219 Escherichia coli O127:H6 str. E2348/69 7064871 YP_002331284.1 CDS xylH NC_011601.1 3986197 3987378 D xylose transport, membrane component; membrane component of ABC superfamily XylH 3986197..3987378 Escherichia coli O127:H6 str. E2348/69 7064872 YP_002331285.1 CDS xylR NC_011601.1 3987456 3988634 D DNA-binding transcriptional activator, xylose-binding 3987456..3988634 Escherichia coli O127:H6 str. E2348/69 7064873 YP_002331286.1 CDS bax NC_011601.1 3988742 3989566 R hypothetical protein complement(3988742..3989566) Escherichia coli O127:H6 str. E2348/69 7064874 YP_002331287.1 CDS malS NC_011601.1 3989886 3991916 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3989886..3991916 Escherichia coli O127:H6 str. E2348/69 7062496 YP_002331288.1 CDS avtA NC_011601.1 3992094 3993347 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3992094..3993347 Escherichia coli O127:H6 str. E2348/69 7065278 YP_002331289.1 CDS ysaA NC_011601.1 3993499 3993972 R hydrogenase, 4Fe-4S ferredoxin-type component complement(3993499..3993972) Escherichia coli O127:H6 str. E2348/69 7062488 YP_002331290.1 CDS yiaJ NC_011601.1 3994074 3994922 R DNA-binding transcriptional repressor complement(3994074..3994922) Escherichia coli O127:H6 str. E2348/69 7063235 YP_002331291.1 CDS yiaK NC_011601.1 3995123 3996121 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3995123..3996121 Escherichia coli O127:H6 str. E2348/69 7064770 YP_002331292.1 CDS yiaL NC_011601.1 3996133 3996597 D hypothetical protein 3996133..3996597 Escherichia coli O127:H6 str. E2348/69 7064771 YP_002331293.1 CDS E2348C_3829 NC_011601.1 3996620 3997540 D hypothetical protein 3996620..3997540 Escherichia coli O127:H6 str. E2348/69 7064772 YP_002331294.1 CDS yiaM NC_011601.1 3997654 3998121 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 3997654..3998121 Escherichia coli O127:H6 str. E2348/69 7062655 YP_002331295.1 CDS yiaN NC_011601.1 3998124 3999401 D transporter, large permease component 3998124..3999401 Escherichia coli O127:H6 str. E2348/69 7064773 YP_002331296.1 CDS yiaO NC_011601.1 3999414 4000400 D transporter, periplasmic protein 3999414..4000400 Escherichia coli O127:H6 str. E2348/69 7064774 YP_002331297.1 CDS lyx NC_011601.1 4000404 4001900 D L-xylulose kinase 4000404..4001900 Escherichia coli O127:H6 str. E2348/69 7064775 YP_002331298.1 CDS sgbH NC_011601.1 4001897 4002559 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4001897..4002559 Escherichia coli O127:H6 str. E2348/69 7065263 YP_002331299.1 CDS sgbU NC_011601.1 4002552 4003412 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4002552..4003412 Escherichia coli O127:H6 str. E2348/69 7062712 YP_002331300.1 CDS sgbE NC_011601.1 4003406 4004101 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4003406..4004101 Escherichia coli O127:H6 str. E2348/69 7062713 YP_002331301.1 CDS aldB NC_011601.1 4004148 4005686 R aldehyde dehydrogenase complement(4004148..4005686) Escherichia coli O127:H6 str. E2348/69 7062711 YP_002331302.1 CDS E2348C_3838 NC_011601.1 4005794 4007089 R hypothetical protein complement(4005794..4007089) Escherichia coli O127:H6 str. E2348/69 7062436 YP_002331303.1 CDS yiaY NC_011601.1 4007219 4008370 R alcohol dehydrogenase complement(4007219..4008370) Escherichia coli O127:H6 str. E2348/69 7062656 YP_002331304.1 CDS selB NC_011601.1 4008559 4010403 R selenocysteinyl-tRNA-specific translation factor complement(4008559..4010403) Escherichia coli O127:H6 str. E2348/69 7064776 YP_002331305.1 CDS selA NC_011601.1 4010400 4011791 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4010400..4011791) Escherichia coli O127:H6 str. E2348/69 7065361 YP_002331306.1 CDS yibF NC_011601.1 4011889 4012497 R glutathione S-transferase complement(4011889..4012497) Escherichia coli O127:H6 str. E2348/69 7065360 YP_002331307.1 CDS yibH NC_011601.1 4012568 4013704 R hypothetical protein complement(4012568..4013704) Escherichia coli O127:H6 str. E2348/69 7064778 YP_002331308.1 CDS yibI NC_011601.1 4013707 4014069 R hypothetical protein complement(4013707..4014069) Escherichia coli O127:H6 str. E2348/69 7064779 YP_002331309.1 CDS mtlA NC_011601.1 4014606 4016519 D fused mannitol-specific PTS enzymes: IIA components /IIB components/IIC components 4014606..4016519 Escherichia coli O127:H6 str. E2348/69 7064780 YP_002331310.1 CDS mtlD NC_011601.1 4016737 4017885 D mannitol-1-phosphate 5-dehydrogenase 4016737..4017885 Escherichia coli O127:H6 str. E2348/69 7060879 YP_002331311.1 CDS mtlR NC_011601.1 4017885 4018472 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4017885..4018472 Escherichia coli O127:H6 str. E2348/69 7060880 YP_002331312.1 CDS yibT NC_011601.1 4018483 4018692 R hypothetical protein complement(4018483..4018692) Escherichia coli O127:H6 str. E2348/69 7060881 YP_002331313.1 CDS yibL NC_011601.1 4018976 4019338 D hypothetical protein 4018976..4019338 Escherichia coli O127:H6 str. E2348/69 7064785 YP_002331314.1 CDS lldP NC_011601.1 4025092 4026747 D L-lactate permease 4025092..4026747 Escherichia coli O127:H6 str. E2348/69 7062658 YP_002331315.1 CDS lldR NC_011601.1 4026747 4027523 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4026747..4027523 Escherichia coli O127:H6 str. E2348/69 7061551 YP_002331316.1 CDS lldD NC_011601.1 4027520 4028710 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4027520..4028710 Escherichia coli O127:H6 str. E2348/69 7061552 YP_002331317.1 CDS yibK NC_011601.1 4028758 4029231 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4028758..4029231 Escherichia coli O127:H6 str. E2348/69 7061550 YP_002331318.1 CDS cysE NC_011601.1 4029284 4030105 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4029284..4030105) Escherichia coli O127:H6 str. E2348/69 7064781 YP_002331319.1 CDS gpsA NC_011601.1 4030185 4031204 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4030185..4031204) Escherichia coli O127:H6 str. E2348/69 7065197 YP_002331320.1 CDS secB NC_011601.1 4031204 4031671 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4031204..4031671) Escherichia coli O127:H6 str. E2348/69 7064237 YP_002331321.1 CDS grxC NC_011601.1 4031735 4031986 R glutaredoxin 3 complement(4031735..4031986) Escherichia coli O127:H6 str. E2348/69 7065353 YP_002331322.1 CDS yibN NC_011601.1 4032127 4032558 R rhodanese-related sulfurtransferase complement(4032127..4032558) Escherichia coli O127:H6 str. E2348/69 7064248 YP_002331323.1 CDS gpmM NC_011601.1 4032803 4034347 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4032803..4034347 Escherichia coli O127:H6 str. E2348/69 7064783 YP_002331324.1 CDS envC NC_011601.1 4034381 4035640 D hypothetical protein 4034381..4035640 Escherichia coli O127:H6 str. E2348/69 7064235 YP_002331325.1 CDS yibQ NC_011601.1 4035644 4036603 D polysaccharide deacetylase 4035644..4036603 Escherichia coli O127:H6 str. E2348/69 7063859 YP_002331326.1 CDS yibD NC_011601.1 4036590 4037624 R glycosyl transferase family protein complement(4036590..4037624) Escherichia coli O127:H6 str. E2348/69 7064784 YP_002331327.1 CDS tdh NC_011601.1 4037863 4038888 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4037863..4038888) Escherichia coli O127:H6 str. E2348/69 7064777 YP_002331328.1 CDS kbl NC_011601.1 4038898 4040094 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase complement(4038898..4040094) Escherichia coli O127:H6 str. E2348/69 7061773 YP_002331329.1 CDS rfaD NC_011601.1 4040308 4041240 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4040308..4041240 Escherichia coli O127:H6 str. E2348/69 7063567 YP_002331330.1 CDS rfaF NC_011601.1 4041250 4042296 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4041250..4042296 Escherichia coli O127:H6 str. E2348/69 7060781 YP_002331331.1 CDS rfaC NC_011601.1 4042300 4043259 D ADP-heptose--LPS heptosyltransferase 4042300..4043259 Escherichia coli O127:H6 str. E2348/69 7060783 YP_002331332.1 CDS rfaL NC_011601.1 4043293 4044510 D lipid A-core: surface polymer ligase 4043293..4044510 Escherichia coli O127:H6 str. E2348/69 7060780 YP_002331333.1 CDS E2348C_3871 NC_011601.1 4044564 4045706 R lipopolysaccharide 1,2-N-acetylglucosamine transferase complement(4044564..4045706) Escherichia coli O127:H6 str. E2348/69 7060788 YP_002331334.1 CDS rfaZ NC_011601.1 4045794 4046567 R lipopolysaccharide core biosynthesis protein complement(4045794..4046567) Escherichia coli O127:H6 str. E2348/69 7062659 YP_002331335.1 CDS rfaY NC_011601.1 4046641 4047339 R lipopolysaccharide core biosynthesis protein complement(4046641..4047339) Escherichia coli O127:H6 str. E2348/69 7060793 YP_002331336.1 CDS rfaJ NC_011601.1 4047357 4048373 R UDP-D-glucose: (galactosyl) lipopolysaccharide glucosyltransferase complement(4047357..4048373) Escherichia coli O127:H6 str. E2348/69 7060792 YP_002331337.1 CDS rfaI NC_011601.1 4048413 4049432 R UDP-D-galactose: (glucosyl) lipopolysaccharide-alpha-1,3-D-galactosyltransferase complement(4048413..4049432) Escherichia coli O127:H6 str. E2348/69 7060787 YP_002331338.1 CDS rfaB NC_011601.1 4049432 4050541 R UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase complement(4049432..4050541) Escherichia coli O127:H6 str. E2348/69 7060786 YP_002331339.1 CDS rfaS NC_011601.1 4050555 4051490 R lipopolysaccharide core biosynthesis protein complement(4050555..4051490) Escherichia coli O127:H6 str. E2348/69 7060779 YP_002331340.1 CDS rfaP NC_011601.1 4051527 4052324 R lipopolysaccharide core biosynthesis heptosyl-I-kinase complement(4051527..4052324) Escherichia coli O127:H6 str. E2348/69 7060791 YP_002331341.1 CDS rfaG NC_011601.1 4052317 4053441 R lipopolysaccharide core biosynthesis glucosyl transferase I complement(4052317..4053441) Escherichia coli O127:H6 str. E2348/69 7060789 YP_002331342.1 CDS rfaQ NC_011601.1 4053438 4054460 R lipopolysaccharide core biosynthesis protein complement(4053438..4054460) Escherichia coli O127:H6 str. E2348/69 7060784 YP_002331343.1 CDS waaA NC_011601.1 4054910 4056187 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4054910..4056187 Escherichia coli O127:H6 str. E2348/69 7060790 YP_002331344.1 CDS coaD NC_011601.1 4056195 4056674 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4056195..4056674 Escherichia coli O127:H6 str. E2348/69 7062364 YP_002331345.1 CDS mutM NC_011601.1 4056713 4057522 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4056713..4057522) Escherichia coli O127:H6 str. E2348/69 7062822 YP_002331346.1 CDS rpmG NC_011601.1 4057620 4057787 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4057620..4057787) Escherichia coli O127:H6 str. E2348/69 7060899 YP_002331347.1 CDS rpmB NC_011601.1 4057808 4058044 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4057808..4058044) Escherichia coli O127:H6 str. E2348/69 7061859 YP_002331348.1 CDS radC NC_011601.1 4058261 4058929 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4058261..4058929) Escherichia coli O127:H6 str. E2348/69 7061854 YP_002331349.1 CDS dfp NC_011601.1 4059101 4060321 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4059101..4060321 Escherichia coli O127:H6 str. E2348/69 7064795 YP_002331350.1 CDS dut NC_011601.1 4060302 4060757 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4060302..4060757 Escherichia coli O127:H6 str. E2348/69 7065013 YP_002331351.1 CDS slmA NC_011601.1 4060864 4061460 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4060864..4061460 Escherichia coli O127:H6 str. E2348/69 7065074 YP_002331352.1 CDS E2348C_3890 NC_011601.1 4061504 4062463 R RNA-directed DNA polymerase complement(4061504..4062463) Escherichia coli O127:H6 str. E2348/69 7062720 YP_002331353.1 CDS pyrE NC_011601.1 4062760 4063401 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4062760..4063401) Escherichia coli O127:H6 str. E2348/69 7061156 YP_002331354.1 CDS rph NC_011601.1 4063467 4064183 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4063467..4064183) Escherichia coli O127:H6 str. E2348/69 7063932 YP_002331355.1 CDS yicC NC_011601.1 4064310 4065173 D hypothetical protein 4064310..4065173 Escherichia coli O127:H6 str. E2348/69 7061826 YP_002331356.1 CDS E2348C_3894 NC_011601.1 4065361 4066620 D integrase 4065361..4066620 Escherichia coli O127:H6 str. E2348/69 7061164 YP_002331357.1 CDS E2348C_3895 NC_011601.1 4067124 4067675 D hypothetical protein 4067124..4067675 Escherichia coli O127:H6 str. E2348/69 7062661 YP_002331358.1 CDS E2348C_3896 NC_011601.1 4067765 4068034 D hypothetical protein 4067765..4068034 Escherichia coli O127:H6 str. E2348/69 7062662 YP_002331359.1 CDS E2348C_3897 NC_011601.1 4068034 4068765 D hypothetical protein 4068034..4068765 Escherichia coli O127:H6 str. E2348/69 7062663 YP_002331360.1 CDS E2348C_3898 NC_011601.1 4068813 4070036 R DNA-bining transcriptional regulator complement(4068813..4070036) Escherichia coli O127:H6 str. E2348/69 7062664 YP_002331361.1 CDS E2348C_3899 NC_011601.1 4070033 4070674 R hypothetical protein complement(4070033..4070674) Escherichia coli O127:H6 str. E2348/69 7062665 YP_002331362.1 CDS E2348C_3900 NC_011601.1 4071210 4071890 D hypothetical protein 4071210..4071890 Escherichia coli O127:H6 str. E2348/69 7062666 YP_002331363.1 CDS E2348C_3901 NC_011601.1 4071993 4072205 D hypothetical protein 4071993..4072205 Escherichia coli O127:H6 str. E2348/69 7062667 YP_002331364.1 CDS E2348C_3902 NC_011601.1 4072213 4072584 D hypothetical protein 4072213..4072584 Escherichia coli O127:H6 str. E2348/69 7062668 YP_002331365.1 CDS E2348C_3903 NC_011601.1 4072589 4072789 D hypothetical protein 4072589..4072789 Escherichia coli O127:H6 str. E2348/69 7062669 YP_002331366.1 CDS E2348C_3904 NC_011601.1 4072782 4072976 D hypothetical protein 4072782..4072976 Escherichia coli O127:H6 str. E2348/69 7062670 YP_002331367.1 CDS E2348C_3905 NC_011601.1 4072969 4073157 D hypothetical protein 4072969..4073157 Escherichia coli O127:H6 str. E2348/69 7062671 YP_002331368.1 CDS E2348C_3906 NC_011601.1 4073150 4073458 D hypothetical protein 4073150..4073458 Escherichia coli O127:H6 str. E2348/69 7062672 YP_002331369.1 CDS E2348C_3907 NC_011601.1 4073458 4073679 D hypothetical protein 4073458..4073679 Escherichia coli O127:H6 str. E2348/69 7062673 YP_002331370.1 CDS E2348C_3908 NC_011601.1 4073676 4076090 D DNA primase 4073676..4076090 Escherichia coli O127:H6 str. E2348/69 7062674 YP_002331371.1 CDS dinD NC_011601.1 4076717 4077541 D DNA-damage-inducible protein D 4076717..4077541 Escherichia coli O127:H6 str. E2348/69 7062675 YP_002331372.1 CDS yicG NC_011601.1 4077833 4078450 D hypothetical protein 4077833..4078450 Escherichia coli O127:H6 str. E2348/69 7065029 YP_002331373.1 CDS ligB NC_011601.1 4078447 4080132 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4078447..4080132) Escherichia coli O127:H6 str. E2348/69 7064788 YP_002331374.1 CDS gmk NC_011601.1 4080390 4081013 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4080390..4081013 Escherichia coli O127:H6 str. E2348/69 7061540 YP_002331375.1 CDS rpoZ NC_011601.1 4081068 4081343 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4081068..4081343 Escherichia coli O127:H6 str. E2348/69 7061731 YP_002331376.1 CDS spoT NC_011601.1 4081362 4083470 D bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4081362..4083470 Escherichia coli O127:H6 str. E2348/69 7061871 YP_002331377.1 CDS trmH NC_011601.1 4083477 4084166 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4083477..4084166 Escherichia coli O127:H6 str. E2348/69 7062749 YP_002331378.1 CDS recG NC_011601.1 4084172 4086253 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4084172..4086253 Escherichia coli O127:H6 str. E2348/69 7062243 YP_002331379.1 CDS gltS NC_011601.1 4086287 4087492 R glutamate transporter complement(4086287..4087492) Escherichia coli O127:H6 str. E2348/69 7063980 YP_002331380.1 CDS yicE NC_011601.1 4087772 4089163 D transporter 4087772..4089163 Escherichia coli O127:H6 str. E2348/69 7061712 YP_002331381.1 CDS yicH NC_011601.1 4089284 4090993 D hypothetical protein 4089284..4090993 Escherichia coli O127:H6 str. E2348/69 7064787 YP_002331382.1 CDS E2348C_3920 NC_011601.1 4091037 4091717 R hypothetical protein complement(4091037..4091717) Escherichia coli O127:H6 str. E2348/69 7064789 YP_002331383.1 CDS E2348C_3921 NC_011601.1 4091698 4092663 R hypothetical protein complement(4091698..4092663) Escherichia coli O127:H6 str. E2348/69 7062676 YP_002331384.1 CDS E2348C_3922 NC_011601.1 4092678 4093538 R hypothetical protein complement(4092678..4093538) Escherichia coli O127:H6 str. E2348/69 7062677 YP_002331385.1 CDS E2348C_3923 NC_011601.1 4093619 4094470 R fructose-bisphosphate aldolase, class-II family complement(4093619..4094470) Escherichia coli O127:H6 str. E2348/69 7062678 YP_002331386.1 CDS E2348C_3924 NC_011601.1 4094482 4095573 R fructose-specific PTS enzymes, IIC component complement(4094482..4095573) Escherichia coli O127:H6 str. E2348/69 7062679 YP_002331387.1 CDS E2348C_3925 NC_011601.1 4095598 4095912 R fructose-specific PTS enzymes, IIB component complement(4095598..4095912) Escherichia coli O127:H6 str. E2348/69 7062680 YP_002331388.1 CDS E2348C_3926 NC_011601.1 4095930 4096400 R fructose-specific PTS enzymes, IIA component complement(4095930..4096400) Escherichia coli O127:H6 str. E2348/69 7062681 YP_002331389.1 CDS E2348C_3927 NC_011601.1 4096427 4097980 R transcriptional antiterminator complement(4096427..4097980) Escherichia coli O127:H6 str. E2348/69 7062682 YP_002331390.1 CDS yicI NC_011601.1 4098275 4100593 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(4098275..4100593) Escherichia coli O127:H6 str. E2348/69 7062683 YP_002331391.1 CDS yicJ NC_011601.1 4100603 4101985 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4100603..4101985) Escherichia coli O127:H6 str. E2348/69 7064790 YP_002331392.1 CDS espF NC_011601.1 4103271 4103891 R LEE-encoded effector EspF complement(4103271..4103891) Escherichia coli O127:H6 str. E2348/69 7061130 YP_002331393.1 CDS E2348C_3931 NC_011601.1 4103976 4104254 R component of T3SS complement(4103976..4104254) Escherichia coli O127:H6 str. E2348/69 7063881 YP_002331394.1 CDS escF NC_011601.1 4104260 4104481 R T3SS structure protein EscF complement(4104260..4104481) Escherichia coli O127:H6 str. E2348/69 7062684 YP_002331395.1 CDS cesD2 NC_011601.1 4104518 4104925 R chaperone CesD2 complement(4104518..4104925) Escherichia coli O127:H6 str. E2348/69 7063869 YP_002331396.1 CDS espB NC_011601.1 4104932 4105897 R translocon EspB complement(4104932..4105897) Escherichia coli O127:H6 str. E2348/69 7064346 YP_002331397.1 CDS espD NC_011601.1 4105918 4107060 R translocon EspD complement(4105918..4107060) Escherichia coli O127:H6 str. E2348/69 7063878 YP_002331398.1 CDS espA NC_011601.1 4107073 4107651 R translocon EspA complement(4107073..4107651) Escherichia coli O127:H6 str. E2348/69 7063880 YP_002331399.1 CDS speL NC_011601.1 4107708 4108763 R secretion switching protein SpeL complement(4107708..4108763) Escherichia coli O127:H6 str. E2348/69 7063877 YP_002331400.1 CDS escD NC_011601.1 4108906 4110126 D T3SS structure protein EscD 4108906..4110126 Escherichia coli O127:H6 str. E2348/69 7062747 YP_002331401.1 CDS eaeA NC_011601.1 4110343 4113162 R intimin EaeA complement(4110343..4113162) Escherichia coli O127:H6 str. E2348/69 7063868 YP_002331402.1 CDS cesT NC_011601.1 4113222 4113692 R chaperone CesT complement(4113222..4113692) Escherichia coli O127:H6 str. E2348/69 7065077 YP_002331403.1 CDS tir NC_011601.1 4113830 4115482 R translocated intimin receptor Tir complement(4113830..4115482) Escherichia coli O127:H6 str. E2348/69 7064348 YP_002331404.1 CDS map NC_011601.1 4115809 4116420 R LEE-encoded effector Map complement(4115809..4116420) Escherichia coli O127:H6 str. E2348/69 7061805 YP_002331405.1 CDS cesF NC_011601.1 4116695 4117057 D chaperone CesF 4116695..4117057 Escherichia coli O127:H6 str. E2348/69 7065290 YP_002331406.1 CDS espH NC_011601.1 4117259 4117765 R LEE-encoded effector EspH complement(4117259..4117765) Escherichia coli O127:H6 str. E2348/69 7064347 YP_002331407.1 CDS sepQ NC_011601.1 4117796 4118713 R T3SS structure protein SepQ complement(4117796..4118713) Escherichia coli O127:H6 str. E2348/69 7063883 YP_002331408.1 CDS E2348C_3946 NC_011601.1 4118676 4119092 R hypothetical protein complement(4118676..4119092) Escherichia coli O127:H6 str. E2348/69 7065364 YP_002331409.1 CDS E2348C_3947 NC_011601.1 4119085 4119462 R hypothetical protein complement(4119085..4119462) Escherichia coli O127:H6 str. E2348/69 7062685 YP_002331410.1 CDS escN NC_011601.1 4119465 4120805 R translocator EscN complement(4119465..4120805) Escherichia coli O127:H6 str. E2348/69 7062686 YP_002331411.1 CDS escV NC_011601.1 4120789 4122816 R translocator EscV complement(4120789..4122816) Escherichia coli O127:H6 str. E2348/69 7063871 YP_002331412.1 CDS mpc NC_011601.1 4122813 4123166 R regulator Mpc complement(4122813..4123166) Escherichia coli O127:H6 str. E2348/69 7063876 YP_002331413.1 CDS espZ NC_011601.1 4123351 4123647 D LEE-encoded effector EspZ 4123351..4123647 Escherichia coli O127:H6 str. E2348/69 7063824 YP_002331414.1 CDS rorf8 NC_011601.1 4123677 4124105 D chaperone of T3SS Rorf8 4123677..4124105 Escherichia coli O127:H6 str. E2348/69 7063884 YP_002331415.1 CDS escJ NC_011601.1 4124108 4124680 D T3SS structure protein EscJ 4124108..4124680 Escherichia coli O127:H6 str. E2348/69 7061824 YP_002331416.1 CDS sepD NC_011601.1 4124686 4125141 D secretion switching protein SepD 4124686..4125141 Escherichia coli O127:H6 str. E2348/69 7063870 YP_002331417.1 CDS escC NC_011601.1 4125141 4126679 D T3SS structure protein EscC 4125141..4126679 Escherichia coli O127:H6 str. E2348/69 7065363 YP_002331418.1 CDS cesD NC_011601.1 4126693 4127148 D chaperone CesD 4126693..4127148 Escherichia coli O127:H6 str. E2348/69 7063867 YP_002331419.1 CDS grlA NC_011601.1 4127532 4127945 R positive regulator GrlA complement(4127532..4127945) Escherichia coli O127:H6 str. E2348/69 7064345 YP_002331420.1 CDS grlR NC_011601.1 4128001 4128372 R negative regulator GrlR complement(4128001..4128372) Escherichia coli O127:H6 str. E2348/69 7064241 YP_002331421.1 CDS E2348C_3959 NC_011601.1 4128568 4129026 D hypothetical protein 4128568..4129026 Escherichia coli O127:H6 str. E2348/69 7064242 YP_002331422.1 CDS escU NC_011601.1 4129023 4130060 R member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli; secretion system apparatus protein SsaU complement(4129023..4130060) Escherichia coli O127:H6 str. E2348/69 7062687 YP_002331423.1 CDS escT NC_011601.1 4130053 4130829 R T3SS structure protein EscT complement(4130053..4130829) Escherichia coli O127:H6 str. E2348/69 7063875 YP_002331424.1 CDS escS NC_011601.1 4130829 4131098 R T3SS structure protein EscS complement(4130829..4131098) Escherichia coli O127:H6 str. E2348/69 7063874 YP_002331425.1 CDS escR NC_011601.1 4131098 4131751 R part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein complement(4131098..4131751) Escherichia coli O127:H6 str. E2348/69 7063873 YP_002331426.1 CDS E2348C_3964 NC_011601.1 4131756 4132451 R component of T3SS complement(4131756..4132451) Escherichia coli O127:H6 str. E2348/69 7063872 YP_002331427.1 CDS E2348C_3965 NC_011601.1 4132396 4132995 R component of T3SS complement(4132396..4132995) Escherichia coli O127:H6 str. E2348/69 7062688 YP_002331428.1 CDS E2348C_3966 NC_011601.1 4132992 4133315 R component of T3SS complement(4132992..4133315) Escherichia coli O127:H6 str. E2348/69 7062689 YP_002331429.1 CDS E2348C_3967 NC_011601.1 4133319 4133537 R component of T3SS complement(4133319..4133537) Escherichia coli O127:H6 str. E2348/69 7062690 YP_002331430.1 CDS ler NC_011601.1 4133552 4133941 R transcriptional regulator Ler complement(4133552..4133941) Escherichia coli O127:H6 str. E2348/69 7062691 YP_002331431.1 CDS E2348C_3969 NC_011601.1 4134445 4134624 R hypothetical protein complement(4134445..4134624) Escherichia coli O127:H6 str. E2348/69 7061520 YP_002331432.1 CDS espG NC_011601.1 4135193 4136389 D LEE-encoded effector EspG 4135193..4136389 Escherichia coli O127:H6 str. E2348/69 7062692 YP_002331433.1 CDS E2348C_3971 NC_011601.1 4136517 4137335 D hypothetical protein 4136517..4137335 Escherichia coli O127:H6 str. E2348/69 7063882 YP_002331434.1 CDS E2348C_3972 NC_011601.1 4137729 4137890 R hypothetical protein complement(4137729..4137890) Escherichia coli O127:H6 str. E2348/69 7062693 YP_002331435.1 CDS E2348C_3973 NC_011601.1 4138106 4138312 R hypothetical protein complement(4138106..4138312) Escherichia coli O127:H6 str. E2348/69 7062694 YP_002331436.1 CDS yicL NC_011601.1 4138354 4139277 D hypothetical protein 4138354..4139277 Escherichia coli O127:H6 str. E2348/69 7062695 YP_002331437.1 CDS nlpA NC_011601.1 4139281 4140099 R hypothetical protein complement(4139281..4140099) Escherichia coli O127:H6 str. E2348/69 7064792 YP_002331438.1 CDS E2348C_3976 NC_011601.1 4140255 4140614 D hypothetical protein 4140255..4140614 Escherichia coli O127:H6 str. E2348/69 7065400 YP_002331439.1 CDS nepI NC_011601.1 4140655 4141845 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4140655..4141845) Escherichia coli O127:H6 str. E2348/69 7062696 YP_002331440.1 CDS yicN NC_011601.1 4142056 4142508 R hypothetical protein complement(4142056..4142508) Escherichia coli O127:H6 str. E2348/69 7065380 YP_002331441.1 CDS yicO NC_011601.1 4142561 4143895 R xanthine/uracil permase complement(4142561..4143895) Escherichia coli O127:H6 str. E2348/69 7064793 YP_002331442.1 CDS uhpT NC_011601.1 4145885 4147276 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4145885..4147276) Escherichia coli O127:H6 str. E2348/69 7062405 YP_002331443.1 CDS uhpC NC_011601.1 4147532 4148851 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4147532..4148851) Escherichia coli O127:H6 str. E2348/69 7062311 YP_002331444.1 CDS uhpB NC_011601.1 4148861 4150363 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4148861..4150363) Escherichia coli O127:H6 str. E2348/69 7062310 YP_002331445.1 CDS uhpA NC_011601.1 4150363 4150953 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4150363..4150953) Escherichia coli O127:H6 str. E2348/69 7062309 YP_002331446.1 CDS ilvN NC_011601.1 4151026 4151316 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4151026..4151316) Escherichia coli O127:H6 str. E2348/69 7062308 YP_002331447.1 CDS ilvB NC_011601.1 4151320 4153008 R acetolactate synthase catalytic subunit complement(4151320..4153008) Escherichia coli O127:H6 str. E2348/69 7063538 YP_002331448.1 CDS ivbL NC_011601.1 4153114 4153212 R ilvB operon leader peptide complement(4153114..4153212) Escherichia coli O127:H6 str. E2348/69 7063529 YP_002331449.1 CDS emrD NC_011601.1 4153613 4154797 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4153613..4154797 Escherichia coli O127:H6 str. E2348/69 7063561 YP_002331450.1 CDS yidF NC_011601.1 4154805 4155302 R DNA-binding transcriptional regulator complement(4154805..4155302) Escherichia coli O127:H6 str. E2348/69 7063846 YP_002331451.1 CDS yidG NC_011601.1 4155299 4155661 R hypothetical protein complement(4155299..4155661) Escherichia coli O127:H6 str. E2348/69 7064799 YP_002331452.1 CDS yidH NC_011601.1 4155651 4155998 R hypothetical protein complement(4155651..4155998) Escherichia coli O127:H6 str. E2348/69 7064800 YP_002331453.1 CDS yidJ NC_011601.1 4156058 4157551 R sulfatase/phosphatase complement(4156058..4157551) Escherichia coli O127:H6 str. E2348/69 7064801 YP_002331454.1 CDS yidK NC_011601.1 4157548 4159263 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4157548..4159263) Escherichia coli O127:H6 str. E2348/69 7064802 YP_002331455.1 CDS yidL NC_011601.1 4159430 4160296 D DNA-binding transcriptional regulator 4159430..4160296 Escherichia coli O127:H6 str. E2348/69 7064803 YP_002331456.1 CDS yidP NC_011601.1 4160386 4162047 R hypothetical protein complement(4160386..4162047) Escherichia coli O127:H6 str. E2348/69 7064804 YP_002331457.1 CDS ibpB NC_011601.1 4162243 4162671 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4162243..4162671) Escherichia coli O127:H6 str. E2348/69 7064805 YP_002331458.1 CDS ibpA NC_011601.1 4162783 4163196 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4162783..4163196) Escherichia coli O127:H6 str. E2348/69 7063516 YP_002331459.1 CDS yidQ NC_011601.1 4163501 4163833 D hypothetical protein 4163501..4163833 Escherichia coli O127:H6 str. E2348/69 7063515 YP_002331460.1 CDS yidR NC_011601.1 4163835 4165049 R hypothetical protein complement(4163835..4165049) Escherichia coli O127:H6 str. E2348/69 7064806 YP_002331461.1 CDS cbrA NC_011601.1 4165150 4166250 D FAD/NAD(P)-binding domain; oxidoreductase 4165150..4166250 Escherichia coli O127:H6 str. E2348/69 7064807 YP_002331462.1 CDS dgoT NC_011601.1 4166211 4167503 R D-galactonate transporter complement(4166211..4167503) Escherichia coli O127:H6 str. E2348/69 7064329 YP_002331463.1 CDS E2348C_4003 NC_011601.1 4168005 4169378 R transposase of ISEc13 complement(4168005..4169378) Escherichia coli O127:H6 str. E2348/69 7061131 YP_002331464.1 CDS dgoA NC_011601.1 4170326 4170943 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4170326..4170943) Escherichia coli O127:H6 str. E2348/69 7062697 YP_002331465.1 CDS dgoK NC_011601.1 4170927 4171805 R 2-oxo-3-deoxygalactonate kinase complement(4170927..4171805) Escherichia coli O127:H6 str. E2348/69 7065015 YP_002331466.1 CDS dgoR NC_011601.1 4171802 4172491 R DNA-binding transcriptional regulator complement(4171802..4172491) Escherichia coli O127:H6 str. E2348/69 7065016 YP_002331467.1 CDS yidX NC_011601.1 4172770 4173426 D hypothetical protein 4172770..4173426 Escherichia coli O127:H6 str. E2348/69 7065017 YP_002331468.1 CDS yidA NC_011601.1 4173470 4174282 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4173470..4174282) Escherichia coli O127:H6 str. E2348/69 7064808 YP_002331469.1 CDS yidB NC_011601.1 4174397 4174795 R hypothetical protein complement(4174397..4174795) Escherichia coli O127:H6 str. E2348/69 7064796 YP_002331470.1 CDS gyrB NC_011601.1 4175029 4177443 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4175029..4177443) Escherichia coli O127:H6 str. E2348/69 7064797 YP_002331471.1 CDS recF NC_011601.1 4177472 4178545 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4177472..4178545) Escherichia coli O127:H6 str. E2348/69 7064279 YP_002331472.1 CDS dnaN NC_011601.1 4178545 4179645 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4178545..4179645) Escherichia coli O127:H6 str. E2348/69 7063979 YP_002331473.1 CDS dnaA NC_011601.1 4179650 4181053 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4179650..4181053) Escherichia coli O127:H6 str. E2348/69 7065051 YP_002331474.1 CDS rpmH NC_011601.1 4181660 4181800 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4181660..4181800 Escherichia coli O127:H6 str. E2348/69 7065044 YP_002331475.1 CDS rnpA NC_011601.1 4181817 4182176 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4181817..4182176 Escherichia coli O127:H6 str. E2348/69 7061860 YP_002331476.1 CDS yidC NC_011601.1 4182400 4184046 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4182400..4184046 Escherichia coli O127:H6 str. E2348/69 7060856 YP_002331477.1 CDS trmE NC_011601.1 4184152 4185516 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4184152..4185516 Escherichia coli O127:H6 str. E2348/69 7064798 YP_002331478.1 CDS tanC NC_011601.1 4185758 4185832 D tryptophanase leader peptide 4185758..4185832 Escherichia coli O127:H6 str. E2348/69 7063801 YP_002331479.1 CDS tnaA NC_011601.1 4186053 4187468 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4186053..4187468 Escherichia coli O127:H6 str. E2348/69 7061752 YP_002331480.1 CDS tnaB NC_011601.1 4187604 4188806 D tryptophan transporter of low affinity; tryptophan permease TnaB 4187604..4188806 Escherichia coli O127:H6 str. E2348/69 7061810 YP_002331481.1 CDS mdtL NC_011601.1 4188938 4190113 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4188938..4190113 Escherichia coli O127:H6 str. E2348/69 7061811 YP_002331482.1 CDS yidZ NC_011601.1 4190088 4191047 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4190088..4191047 Escherichia coli O127:H6 str. E2348/69 7065317 YP_002331483.1 CDS yieE NC_011601.1 4191192 4191953 D phosphopantetheinyl transferase 4191192..4191953 Escherichia coli O127:H6 str. E2348/69 7064809 YP_002331484.1 CDS yieF NC_011601.1 4191975 4192541 D chromate reductase, Class I, flavoprotein 4191975..4192541 Escherichia coli O127:H6 str. E2348/69 7064810 YP_002331485.1 CDS yieG NC_011601.1 4192595 4193932 R hypothetical protein complement(4192595..4193932) Escherichia coli O127:H6 str. E2348/69 7064811 YP_002331486.1 CDS yieH NC_011601.1 4194099 4194764 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4194099..4194764 Escherichia coli O127:H6 str. E2348/69 7064812 YP_002331487.1 CDS cbrB NC_011601.1 4194831 4195304 D might be involved in hypersensitivity to nitrofurzone; hypothetical protein 4194831..4195304 Escherichia coli O127:H6 str. E2348/69 7064813 YP_002331488.1 CDS yieL NC_011601.1 4196123 4197292 R xylanase complement(4196123..4197292) Escherichia coli O127:H6 str. E2348/69 7064814 YP_002331489.1 CDS bglH NC_011601.1 4197319 4198935 R carbohydrate-specific outer membrane porin, cryptic complement(4197319..4198935) Escherichia coli O127:H6 str. E2348/69 7064815 YP_002331490.1 CDS bglB NC_011601.1 4199021 4200415 R cryptic phospho-beta-glucosidase B complement(4199021..4200415) Escherichia coli O127:H6 str. E2348/69 7062516 YP_002331491.1 CDS bglF NC_011601.1 4200434 4202308 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC complement(4200434..4202308) Escherichia coli O127:H6 str. E2348/69 7062513 YP_002331492.1 CDS bglG NC_011601.1 4202441 4203277 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4202441..4203277) Escherichia coli O127:H6 str. E2348/69 7062514 YP_002331493.1 CDS phoU NC_011601.1 4203563 4204288 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4203563..4204288) Escherichia coli O127:H6 str. E2348/69 7062515 YP_002331494.1 CDS pstB NC_011601.1 4204303 4205076 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4204303..4205076) Escherichia coli O127:H6 str. E2348/69 7060749 YP_002331495.1 CDS pstA NC_011601.1 4205167 4206057 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4205167..4206057) Escherichia coli O127:H6 str. E2348/69 7061330 YP_002331496.1 CDS pstC NC_011601.1 4206057 4207016 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4206057..4207016) Escherichia coli O127:H6 str. E2348/69 7061329 YP_002331497.1 CDS pstS NC_011601.1 4207103 4208143 R phosphate ABC transporter substrate-binding protein complement(4207103..4208143) Escherichia coli O127:H6 str. E2348/69 7061331 YP_002331498.1 CDS glmS NC_011601.1 4208457 4210286 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4208457..4210286) Escherichia coli O127:H6 str. E2348/69 7061332 YP_002331499.1 CDS glmU NC_011601.1 4210448 4211818 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4210448..4211818) Escherichia coli O127:H6 str. E2348/69 7061674 YP_002331500.1 CDS atpC NC_011601.1 4212172 4212591 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(4212172..4212591) Escherichia coli O127:H6 str. E2348/69 7061675 YP_002331501.1 CDS atpD NC_011601.1 4212612 4213994 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(4212612..4213994) Escherichia coli O127:H6 str. E2348/69 7062481 YP_002331502.1 CDS atpG NC_011601.1 4214021 4214884 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(4214021..4214884) Escherichia coli O127:H6 str. E2348/69 7062482 YP_002331503.1 CDS atpA NC_011601.1 4214935 4216476 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(4214935..4216476) Escherichia coli O127:H6 str. E2348/69 7062485 YP_002331504.1 CDS atpH NC_011601.1 4216489 4217022 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(4216489..4217022) Escherichia coli O127:H6 str. E2348/69 7062479 YP_002331505.1 CDS atpF NC_011601.1 4217037 4217507 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(4217037..4217507) Escherichia coli O127:H6 str. E2348/69 7062486 YP_002331506.1 CDS atpE NC_011601.1 4217569 4217808 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(4217569..4217808) Escherichia coli O127:H6 str. E2348/69 7062484 YP_002331507.1 CDS atpB NC_011601.1 4217855 4218670 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(4217855..4218670) Escherichia coli O127:H6 str. E2348/69 7062483 YP_002331508.1 CDS atpI NC_011601.1 4218679 4219059 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4218679..4219059) Escherichia coli O127:H6 str. E2348/69 7062480 YP_002331509.1 CDS gidB NC_011601.1 4219676 4220299 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4219676..4220299) Escherichia coli O127:H6 str. E2348/69 7062487 YP_002331510.1 CDS mnmG NC_011601.1 4220363 4222252 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4220363..4222252) Escherichia coli O127:H6 str. E2348/69 7061656 YP_002331511.1 CDS mioC NC_011601.1 4222631 4223074 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4222631..4223074) Escherichia coli O127:H6 str. E2348/69 7063802 YP_002331512.1 CDS asnC NC_011601.1 4223164 4223622 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4223164..4223622) Escherichia coli O127:H6 str. E2348/69 7063791 YP_002331513.1 CDS asnA NC_011601.1 4223774 4224766 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4223774..4224766 Escherichia coli O127:H6 str. E2348/69 7061413 YP_002331514.1 CDS yieM NC_011601.1 4224771 4226222 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4224771..4226222) Escherichia coli O127:H6 str. E2348/69 7061411 YP_002331515.1 CDS ravA NC_011601.1 4226216 4227712 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4226216..4227712) Escherichia coli O127:H6 str. E2348/69 7062360 YP_002331516.1 CDS trkD NC_011601.1 4227935 4229803 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4227935..4229803 Escherichia coli O127:H6 str. E2348/69 7063950 YP_002331517.1 CDS rbsD NC_011601.1 4229970 4230389 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4229970..4230389 Escherichia coli O127:H6 str. E2348/69 7061507 YP_002331518.1 CDS rbsA NC_011601.1 4230397 4231902 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4230397..4231902 Escherichia coli O127:H6 str. E2348/69 7063957 YP_002331519.1 CDS rbsC NC_011601.1 4231907 4232872 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4231907..4232872 Escherichia coli O127:H6 str. E2348/69 7063954 YP_002331520.1 CDS rbsB NC_011601.1 4232897 4233787 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4232897..4233787 Escherichia coli O127:H6 str. E2348/69 7063956 YP_002331521.1 CDS rbsK NC_011601.1 4233913 4234842 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4233913..4234842 Escherichia coli O127:H6 str. E2348/69 7063955 YP_002331522.1 CDS rbsR NC_011601.1 4234846 4235838 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4234846..4235838 Escherichia coli O127:H6 str. E2348/69 7063958 YP_002331523.1 CDS hsrA NC_011601.1 4235804 4237231 R multidrug or homocysteine efflux system protein HsrA complement(4235804..4237231) Escherichia coli O127:H6 str. E2348/69 7063959 YP_002331524.1 CDS yieP NC_011601.1 4237254 4237946 R transcriptional regulator complement(4237254..4237946) Escherichia coli O127:H6 str. E2348/69 7062188 YP_002331525.1 CDS hdfR NC_011601.1 4243750 4244589 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4243750..4244589) Escherichia coli O127:H6 str. E2348/69 7062262 YP_002331526.1 CDS yifE NC_011601.1 4244708 4245046 D hypothetical protein 4244708..4245046 Escherichia coli O127:H6 str. E2348/69 7064288 YP_002331527.1 CDS yifB NC_011601.1 4245071 4246591 R among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4245071..4246591) Escherichia coli O127:H6 str. E2348/69 7064818 YP_002331528.1 CDS ilvL NC_011601.1 4246944 4247042 D ilvG operon leader peptide 4246944..4247042 Escherichia coli O127:H6 str. E2348/69 7064817 YP_002331529.1 CDS ilvG NC_011601.1 4247182 4248828 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4247182..4248828 Escherichia coli O127:H6 str. E2348/69 7063536 YP_002331530.1 CDS ilvM NC_011601.1 4248825 4249088 D acetolactate synthase 2 regulatory subunit 4248825..4249088 Escherichia coli O127:H6 str. E2348/69 7063533 YP_002331531.1 CDS ilvE NC_011601.1 4249108 4250037 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4249108..4250037 Escherichia coli O127:H6 str. E2348/69 7063537 YP_002331532.1 CDS ilvD NC_011601.1 4250102 4251952 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4250102..4251952 Escherichia coli O127:H6 str. E2348/69 7063532 YP_002331533.1 CDS ilvA NC_011601.1 4251955 4253499 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4251955..4253499 Escherichia coli O127:H6 str. E2348/69 7063531 YP_002331534.1 CDS ilvY NC_011601.1 4253496 4254386 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4253496..4254386) Escherichia coli O127:H6 str. E2348/69 7063528 YP_002331535.1 CDS ilvC NC_011601.1 4254536 4256011 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4254536..4256011 Escherichia coli O127:H6 str. E2348/69 7063539 YP_002331536.1 CDS ppiC NC_011601.1 4256057 4256338 R peptidyl-prolyl cis-trans isomerase C complement(4256057..4256338) Escherichia coli O127:H6 str. E2348/69 7063530 YP_002331537.1 CDS rep NC_011601.1 4256425 4258446 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4256425..4258446 Escherichia coli O127:H6 str. E2348/69 7061272 YP_002331538.1 CDS gpp NC_011601.1 4258493 4259977 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4258493..4259977) Escherichia coli O127:H6 str. E2348/69 7060699 YP_002331539.1 CDS rhlB NC_011601.1 4260113 4261378 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4260113..4261378) Escherichia coli O127:H6 str. E2348/69 7064236 YP_002331540.1 CDS trxA NC_011601.1 4261509 4261838 D thioredoxin 4261509..4261838 Escherichia coli O127:H6 str. E2348/69 7060810 YP_002331541.1 CDS rhoL NC_011601.1 4261979 4262080 D rho operon leader peptide 4261979..4262080 Escherichia coli O127:H6 str. E2348/69 7062267 YP_002331542.1 CDS rho NC_011601.1 4262165 4263424 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4262165..4263424 Escherichia coli O127:H6 str. E2348/69 7060813 YP_002331543.1 CDS E2348C_4084 NC_011601.1 4263434 4263652 D hypothetical protein 4263434..4263652 Escherichia coli O127:H6 str. E2348/69 7060812 YP_002331544.1 CDS rfe NC_011601.1 4263664 4264767 D UDP-GlcNAc: undecaprenylphosphate GlcNAc-1-phosphate transferase 4263664..4264767 Escherichia coli O127:H6 str. E2348/69 7062698 YP_002331545.1 CDS wzzE NC_011601.1 4264779 4265825 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4264779..4265825 Escherichia coli O127:H6 str. E2348/69 7060794 YP_002331546.1 CDS rffE NC_011601.1 4265881 4267011 D UDP-N-acetyl glucosamine-2-epimerase 4265881..4267011 Escherichia coli O127:H6 str. E2348/69 7064855 YP_002331547.1 CDS wecC NC_011601.1 4267008 4268270 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4267008..4268270 Escherichia coli O127:H6 str. E2348/69 7060798 YP_002331548.1 CDS rffG NC_011601.1 4268270 4269337 D dTDP-glucose 4,6-dehydratase 4268270..4269337 Escherichia coli O127:H6 str. E2348/69 7060797 YP_002331549.1 CDS rffH NC_011601.1 4269356 4270237 D glucose-1-phosphate thymidylyltransferase 4269356..4270237 Escherichia coli O127:H6 str. E2348/69 7060799 YP_002331550.1 CDS rffC NC_011601.1 4270215 4270889 D TDP-fucosamine acetyltransferase 4270215..4270889 Escherichia coli O127:H6 str. E2348/69 7060800 YP_002331551.1 CDS rffA NC_011601.1 4270894 4272024 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4270894..4272024 Escherichia coli O127:H6 str. E2348/69 7060796 YP_002331552.1 CDS wzxE NC_011601.1 4272026 4273276 D O-antigen translocase 4272026..4273276 Escherichia coli O127:H6 str. E2348/69 7060795 YP_002331553.1 CDS rffT NC_011601.1 4273273 4274352 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4273273..4274352 Escherichia coli O127:H6 str. E2348/69 7064851 YP_002331554.1 CDS wzyE NC_011601.1 4274349 4275701 D enterobacterial common antigen polymerase; common antigen polymerase 4274349..4275701 Escherichia coli O127:H6 str. E2348/69 7060802 YP_002331555.1 CDS rffM NC_011601.1 4275704 4276444 D UDP-N-acetyl-D-mannosaminuronic acid transferase 4275704..4276444 Escherichia coli O127:H6 str. E2348/69 7064853 YP_002331556.1 CDS yifK NC_011601.1 4276635 4278020 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4276635..4278020 Escherichia coli O127:H6 str. E2348/69 7060801 YP_002331557.1 CDS aslB NC_011601.1 4278705 4279940 D regulator of arylsulfatase activity 4278705..4279940 Escherichia coli O127:H6 str. E2348/69 7061301 YP_002331558.1 CDS aslA NC_011601.1 4280031 4281686 R acrylsulfatase-like protein complement(4280031..4281686) Escherichia coli O127:H6 str. E2348/69 7061409 YP_002331559.1 CDS hemY NC_011601.1 4282365 4283561 R protoheme IX biogenesis protein complement(4282365..4283561) Escherichia coli O127:H6 str. E2348/69 7065324 YP_002331560.1 CDS hemX NC_011601.1 4283564 4284781 R uroporphyrinogen III C-methyltransferase complement(4283564..4284781) Escherichia coli O127:H6 str. E2348/69 7064302 YP_002331561.1 CDS hemD NC_011601.1 4284803 4285543 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4284803..4285543) Escherichia coli O127:H6 str. E2348/69 7064301 YP_002331562.1 CDS hemC NC_011601.1 4285540 4286502 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4285540..4286502) Escherichia coli O127:H6 str. E2348/69 7064294 YP_002331563.1 CDS cyaA NC_011601.1 4286868 4289414 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4286868..4289414 Escherichia coli O127:H6 str. E2348/69 7064293 YP_002331564.1 CDS cyaY NC_011601.1 4289454 4289774 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4289454..4289774) Escherichia coli O127:H6 str. E2348/69 7065179 YP_002331565.1 CDS E2348C_4106 NC_011601.1 4289822 4291150 R hypothetical protein complement(4289822..4291150) Escherichia coli O127:H6 str. E2348/69 7065180 YP_002331566.1 CDS E2348C_4107 NC_011601.1 4291147 4292637 R lipoprotein complement(4291147..4292637) Escherichia coli O127:H6 str. E2348/69 7062699 YP_002331567.1 CDS yifL NC_011601.1 4292826 4293029 D lipoprotein 4292826..4293029 Escherichia coli O127:H6 str. E2348/69 7062700 YP_002331568.1 CDS dapF NC_011601.1 4293066 4293890 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4293066..4293890 Escherichia coli O127:H6 str. E2348/69 7064820 YP_002331569.1 CDS yigA NC_011601.1 4293887 4294594 D hypothetical protein 4293887..4294594 Escherichia coli O127:H6 str. E2348/69 7065224 YP_002331570.1 CDS xerC NC_011601.1 4294591 4295487 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4294591..4295487 Escherichia coli O127:H6 str. E2348/69 7064821 YP_002331571.1 CDS yigB NC_011601.1 4295487 4296203 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4295487..4296203 Escherichia coli O127:H6 str. E2348/69 7064863 YP_002331572.1 CDS uvrD NC_011601.1 4296287 4298449 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4296287..4298449 Escherichia coli O127:H6 str. E2348/69 7064822 YP_002331573.1 CDS E2348C_4114 NC_011601.1 4298504 4299406 R hypothetical protein complement(4298504..4299406) Escherichia coli O127:H6 str. E2348/69 7062343 YP_002331574.1 CDS yigE NC_011601.1 4299489 4300253 R hypothetical protein complement(4299489..4300253) Escherichia coli O127:H6 str. E2348/69 7062701 YP_002331575.1 CDS corA NC_011601.1 4300623 4301573 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4300623..4301573 Escherichia coli O127:H6 str. E2348/69 7064823 YP_002331576.1 CDS E2348C_4117 NC_011601.1 4301609 4302106 R hypothetical protein complement(4301609..4302106) Escherichia coli O127:H6 str. E2348/69 7062833 YP_002331577.1 CDS E2348C_4118 NC_011601.1 4302103 4302951 R hypothetical protein complement(4302103..4302951) Escherichia coli O127:H6 str. E2348/69 7062702 YP_002331578.1 CDS rarD NC_011601.1 4303262 4304152 R chloramphenical resistance permease complement(4303262..4304152) Escherichia coli O127:H6 str. E2348/69 7062703 YP_002331579.1 CDS yigI NC_011601.1 4304204 4304671 R hypothetical protein complement(4304204..4304671) Escherichia coli O127:H6 str. E2348/69 7063949 YP_002331580.1 CDS pldA NC_011601.1 4304836 4305705 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4304836..4305705 Escherichia coli O127:H6 str. E2348/69 7064824 YP_002331581.1 CDS recQ NC_011601.1 4305830 4307659 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4305830..4307659 Escherichia coli O127:H6 str. E2348/69 7060754 YP_002331582.1 CDS rhtC NC_011601.1 4307723 4308343 D threonine efflux system 4307723..4308343 Escherichia coli O127:H6 str. E2348/69 7063984 YP_002331583.1 CDS E2348C_4124 NC_011601.1 4308380 4309240 R transposase complement(4308380..4309240) Escherichia coli O127:H6 str. E2348/69 7060816 YP_002331584.1 CDS rhtB NC_011601.1 4309399 4310019 R homoserine/homoserine lactone efflux protein complement(4309399..4310019) Escherichia coli O127:H6 str. E2348/69 7065004 YP_002331585.1 CDS pldB NC_011601.1 4310130 4311152 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4310130..4311152 Escherichia coli O127:H6 str. E2348/69 7060815 YP_002331586.1 CDS yigL NC_011601.1 4311160 4311960 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4311160..4311960 Escherichia coli O127:H6 str. E2348/69 7060755 YP_002331587.1 CDS yigM NC_011601.1 4312036 4312935 D hypothetical protein 4312036..4312935 Escherichia coli O127:H6 str. E2348/69 7064825 YP_002331588.1 CDS metR NC_011601.1 4312823 4313776 R DNA-binding transcriptional activator MetR complement(4312823..4313776) Escherichia coli O127:H6 str. E2348/69 7064826 YP_002331589.1 CDS metE NC_011601.1 4313894 4316155 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4313894..4316155 Escherichia coli O127:H6 str. E2348/69 7063769 YP_002331590.1 CDS E2348C_4131 NC_011601.1 4316482 4317051 D phosphosugar isomerase 4316482..4317051 Escherichia coli O127:H6 str. E2348/69 7063759 YP_002331591.1 CDS E2348C_4132 NC_011601.1 4317093 4318601 D PTS system, IIB component / IIC component 4317093..4318601 Escherichia coli O127:H6 str. E2348/69 7065084 YP_002331592.1 CDS E2348C_4133 NC_011601.1 4318652 4320649 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4318652..4320649 Escherichia coli O127:H6 str. E2348/69 7065085 YP_002331593.1 CDS E2348C_4134 NC_011601.1 4320679 4321524 R RpiR family transcriptional regulator complement(4320679..4321524) Escherichia coli O127:H6 str. E2348/69 7065086 YP_002331594.1 CDS E2348C_4135 NC_011601.1 4321724 4322629 R LysR family transcriptional regulator complement(4321724..4322629) Escherichia coli O127:H6 str. E2348/69 7065087 YP_002331595.1 CDS E2348C_4136 NC_011601.1 4322707 4323930 R permease, cytosine/purine, uracil, thiamine, allantoin family complement(4322707..4323930) Escherichia coli O127:H6 str. E2348/69 7065088 YP_002331596.1 CDS E2348C_4137 NC_011601.1 4323956 4324345 R hypothetical protein complement(4323956..4324345) Escherichia coli O127:H6 str. E2348/69 7065089 YP_002331597.1 CDS E2348C_4138 NC_011601.1 4324362 4325318 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4324362..4325318) Escherichia coli O127:H6 str. E2348/69 7065090 YP_002331598.1 CDS E2348C_4140 NC_011601.1 4325668 4327041 D transposase of ISEc13 4325668..4327041 Escherichia coli O127:H6 str. E2348/69 7061132 YP_002331599.1 CDS E2348C_4141 NC_011601.1 4328290 4329849 R FdrA-like protein complement(4328290..4329849) Escherichia coli O127:H6 str. E2348/69 7065092 YP_002331600.1 CDS E2348C_4142 NC_011601.1 4329944 4330804 R hypothetical protein complement(4329944..4330804) Escherichia coli O127:H6 str. E2348/69 7065093 YP_002331601.1 CDS E2348C_4143 NC_011601.1 4330810 4331478 R cysteine hydrolases superfamily protein complement(4330810..4331478) Escherichia coli O127:H6 str. E2348/69 7065094 YP_002331602.1 CDS ysgA NC_011601.1 4331735 4332544 R hydrolase complement(4331735..4332544) Escherichia coli O127:H6 str. E2348/69 7065095 YP_002331603.1 CDS udp NC_011601.1 4332806 4333567 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4332806..4333567 Escherichia coli O127:H6 str. E2348/69 7063238 YP_002331604.1 CDS rmuC NC_011601.1 4333708 4335135 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4333708..4335135 Escherichia coli O127:H6 str. E2348/69 7062301 YP_002331605.1 CDS ubiE NC_011601.1 4335230 4335985 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4335230..4335985 Escherichia coli O127:H6 str. E2348/69 7060845 YP_002331606.1 CDS yigP NC_011601.1 4335999 4336604 D hypothetical protein 4335999..4336604 Escherichia coli O127:H6 str. E2348/69 7062294 YP_002331607.1 CDS ubiB NC_011601.1 4336601 4338241 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4336601..4338241 Escherichia coli O127:H6 str. E2348/69 7064827 YP_002331608.1 CDS tatA NC_011601.1 4338320 4338589 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4338320..4338589 Escherichia coli O127:H6 str. E2348/69 7062291 YP_002331609.1 CDS tatB NC_011601.1 4338593 4339108 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4338593..4339108 Escherichia coli O127:H6 str. E2348/69 7061755 YP_002331610.1 CDS tatC NC_011601.1 4339111 4339887 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4339111..4339887 Escherichia coli O127:H6 str. E2348/69 7061756 YP_002331611.1 CDS tatD NC_011601.1 4339929 4340711 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4339929..4340711 Escherichia coli O127:H6 str. E2348/69 7061757 YP_002331612.1 CDS rfaH NC_011601.1 4340708 4341196 R transcriptional activator RfaH complement(4340708..4341196) Escherichia coli O127:H6 str. E2348/69 7061758 YP_002331613.1 CDS ubiD NC_011601.1 4341363 4342856 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4341363..4342856 Escherichia coli O127:H6 str. E2348/69 7060785 YP_002331614.1 CDS fre NC_011601.1 4342902 4343603 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4342902..4343603 Escherichia coli O127:H6 str. E2348/69 7062293 YP_002331615.1 CDS fadA NC_011601.1 4343886 4345049 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4343886..4345049) Escherichia coli O127:H6 str. E2348/69 7061953 YP_002331616.1 CDS fadB NC_011601.1 4345059 4347248 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4345059..4347248) Escherichia coli O127:H6 str. E2348/69 7062071 YP_002331617.1 CDS pepQ NC_011601.1 4347438 4348769 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4347438..4348769 Escherichia coli O127:H6 str. E2348/69 7062072 YP_002331618.1 CDS yigZ NC_011601.1 4348769 4349383 D hypothetical protein 4348769..4349383 Escherichia coli O127:H6 str. E2348/69 7060704 YP_002331619.1 CDS trkH NC_011601.1 4349422 4350873 D potassium transporter 4349422..4350873 Escherichia coli O127:H6 str. E2348/69 7064828 YP_002331620.1 CDS hemG NC_011601.1 4350885 4351430 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4350885..4351430 Escherichia coli O127:H6 str. E2348/69 7062240 YP_002331621.1 CDS mobB NC_011601.1 4357019 4357546 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4357019..4357546) Escherichia coli O127:H6 str. E2348/69 7061896 YP_002331622.1 CDS mobA NC_011601.1 4357528 4358112 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4357528..4358112) Escherichia coli O127:H6 str. E2348/69 7063811 YP_002331623.1 CDS yihD NC_011601.1 4358182 4358451 D hypothetical protein 4358182..4358451 Escherichia coli O127:H6 str. E2348/69 7063810 YP_002331624.1 CDS rdoA NC_011601.1 4358528 4359514 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4358528..4359514 Escherichia coli O127:H6 str. E2348/69 7064830 YP_002331625.1 CDS dsbA NC_011601.1 4359531 4360157 D protein disulfide isomerase I 4359531..4360157 Escherichia coli O127:H6 str. E2348/69 7063974 YP_002331626.1 CDS yihF NC_011601.1 4360312 4361742 D hypothetical protein 4360312..4361742 Escherichia coli O127:H6 str. E2348/69 7065062 YP_002331627.1 CDS yihG NC_011601.1 4361783 4362715 R acyltransferase complement(4361783..4362715) Escherichia coli O127:H6 str. E2348/69 7064831 YP_002331628.1 CDS polA NC_011601.1 4363079 4365865 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4363079..4365865 Escherichia coli O127:H6 str. E2348/69 7064832 YP_002331629.1 CDS engB NC_011601.1 4366247 4366879 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4366247..4366879) Escherichia coli O127:H6 str. E2348/69 7062748 YP_002331630.1 CDS yihI NC_011601.1 4367461 4367970 D hypothetical protein 4367461..4367970 Escherichia coli O127:H6 str. E2348/69 7065164 YP_002331631.1 CDS hemN NC_011601.1 4368159 4369532 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4368159..4369532 Escherichia coli O127:H6 str. E2348/69 7064833 YP_002331632.1 CDS glnG NC_011601.1 4369987 4371396 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4369987..4371396) Escherichia coli O127:H6 str. E2348/69 7064300 YP_002331633.1 CDS glnL NC_011601.1 4371408 4372457 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4371408..4372457) Escherichia coli O127:H6 str. E2348/69 7061680 YP_002331634.1 CDS glnA NC_011601.1 4372631 4374040 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4372631..4374040) Escherichia coli O127:H6 str. E2348/69 7061683 YP_002331635.1 CDS typA NC_011601.1 4374413 4376236 D GTP-binding protein 4374413..4376236 Escherichia coli O127:H6 str. E2348/69 7061676 YP_002331636.1 CDS E2348C_4178 NC_011601.1 4376343 4377131 R DNA-binding transcriptional regulator complement(4376343..4377131) Escherichia coli O127:H6 str. E2348/69 7062282 YP_002331637.1 CDS E2348C_4179 NC_011601.1 4377171 4378067 R sugar kinase complement(4377171..4378067) Escherichia coli O127:H6 str. E2348/69 7065096 YP_002331638.1 CDS E2348C_4180 NC_011601.1 4378240 4379118 D oxidoreductase with NAD(P)-binding Rossmann-fold domain 4378240..4379118 Escherichia coli O127:H6 str. E2348/69 7065097 YP_002331639.1 CDS E2348C_4181 NC_011601.1 4379143 4380030 D aldolase 4379143..4380030 Escherichia coli O127:H6 str. E2348/69 7065098 YP_002331640.1 CDS E2348C_4182 NC_011601.1 4380063 4381073 D dehydrogenase 4380063..4381073 Escherichia coli O127:H6 str. E2348/69 7065099 YP_002331641.1 CDS E2348C_4183 NC_011601.1 4381143 4382576 D transporter 4381143..4382576 Escherichia coli O127:H6 str. E2348/69 7065100 YP_002331642.1 CDS E2348C_4184 NC_011601.1 4382675 4384024 D shikimate transporter 4382675..4384024 Escherichia coli O127:H6 str. E2348/69 7065101 YP_002331643.1 CDS yihW NC_011601.1 4384014 4384901 D aldose-1-epimerase 4384014..4384901 Escherichia coli O127:H6 str. E2348/69 7065102 YP_002331644.1 CDS yihX NC_011601.1 4385042 4385641 D phosphatase 4385042..4385641 Escherichia coli O127:H6 str. E2348/69 7064834 YP_002331645.1 CDS rbn NC_011601.1 4385635 4386507 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4385635..4386507 Escherichia coli O127:H6 str. E2348/69 7064835 YP_002331646.1 CDS dtd NC_011601.1 4386504 4386941 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4386504..4386941 Escherichia coli O127:H6 str. E2348/69 7064836 YP_002331647.1 CDS yiiD NC_011601.1 4386986 4387927 D acetyltransferase 4386986..4387927 Escherichia coli O127:H6 str. E2348/69 7065070 YP_002331648.1 CDS E2348C_4190 NC_011601.1 4387991 4388899 R lipase complement(4387991..4388899) Escherichia coli O127:H6 str. E2348/69 7064837 YP_002331649.1 CDS E2348C_4191 NC_011601.1 4389128 4389439 D hypothetical protein 4389128..4389439 Escherichia coli O127:H6 str. E2348/69 7065103 YP_002331650.1 CDS E2348C_4192 NC_011601.1 4389440 4389730 D hypothetical protein 4389440..4389730 Escherichia coli O127:H6 str. E2348/69 7065104 YP_002331651.1 CDS yiiE NC_011601.1 4390335 4390553 D transcriptional regulator 4390335..4390553 Escherichia coli O127:H6 str. E2348/69 7065105 YP_002331652.1 CDS fdhE NC_011601.1 4390777 4391706 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4390777..4391706) Escherichia coli O127:H6 str. E2348/69 7064838 YP_002331653.1 CDS fdoI NC_011601.1 4391703 4392338 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4391703..4392338) Escherichia coli O127:H6 str. E2348/69 7062086 YP_002331654.1 CDS fdoH NC_011601.1 4392335 4393237 R formate dehydrogenase-O, Fe-S subunit FdoH complement(4392335..4393237) Escherichia coli O127:H6 str. E2348/69 7062093 YP_002331655.1 CDS fdoG NC_011601.1 4393250 4396300 R selenocysteine (Sec=>U); formate dehydrogenase-O, large subunit complement(4393250..4396300) Escherichia coli O127:H6 str. E2348/69 7062092 YP_002331656.1 CDS fdhD NC_011601.1 4396494 4397330 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4396494..4397330 Escherichia coli O127:H6 str. E2348/69 7062091 YP_002331657.1 CDS E2348C_4199 NC_011601.1 4397641 4399476 D heat shock protein (Hsp90-family) 4397641..4399476 Escherichia coli O127:H6 str. E2348/69 7062085 YP_002331658.1 CDS E2348C_4200 NC_011601.1 4399478 4401784 D hypothetical protein 4399478..4401784 Escherichia coli O127:H6 str. E2348/69 7065106 YP_002331659.1 CDS frvR NC_011601.1 4401882 4403630 R repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein complement(4401882..4403630) Escherichia coli O127:H6 str. E2348/69 7065107 YP_002331660.1 CDS frvX NC_011601.1 4403630 4404700 R with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX complement(4403630..4404700) Escherichia coli O127:H6 str. E2348/69 7061965 YP_002331661.1 CDS frvB NC_011601.1 4404690 4406141 R PTS system transporter subunits IIBC complement(4404690..4406141) Escherichia coli O127:H6 str. E2348/69 7061966 YP_002331662.1 CDS frvA NC_011601.1 4406152 4406598 R with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA complement(4406152..4406598) Escherichia coli O127:H6 str. E2348/69 7061964 YP_002331663.1 CDS E2348C_4205 NC_011601.1 4407074 4408468 D glycoprotein 4407074..4408468 Escherichia coli O127:H6 str. E2348/69 7061963 YP_002331664.1 CDS rhaM NC_011601.1 4408509 4408823 R L-rhamnose mutarotase complement(4408509..4408823) Escherichia coli O127:H6 str. E2348/69 7065108 YP_002331665.1 CDS rhaD NC_011601.1 4408833 4409657 R rhamnulose-1-phosphate aldolase complement(4408833..4409657) Escherichia coli O127:H6 str. E2348/69 7060806 YP_002331666.1 CDS rhaA NC_011601.1 4409848 4411107 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4409848..4411107) Escherichia coli O127:H6 str. E2348/69 7060805 YP_002331667.1 CDS rhaB NC_011601.1 4411104 4412573 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4411104..4412573) Escherichia coli O127:H6 str. E2348/69 7060803 YP_002331668.1 CDS rhaS NC_011601.1 4412861 4413697 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4412861..4413697 Escherichia coli O127:H6 str. E2348/69 7060804 YP_002331669.1 CDS rhaR NC_011601.1 4413681 4414619 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4413681..4414619 Escherichia coli O127:H6 str. E2348/69 7060808 YP_002331670.1 CDS rhaT NC_011601.1 4414616 4415650 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4414616..4415650) Escherichia coli O127:H6 str. E2348/69 7060807 YP_002331671.1 CDS sodA NC_011601.1 4415936 4416556 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4415936..4416556 Escherichia coli O127:H6 str. E2348/69 7060809 YP_002331672.1 CDS kdgT NC_011601.1 4416816 4417799 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4416816..4417799 Escherichia coli O127:H6 str. E2348/69 7062732 YP_002331673.1 CDS yiiM NC_011601.1 4417948 4418622 D hypothetical protein 4417948..4418622 Escherichia coli O127:H6 str. E2348/69 7063571 YP_002331674.1 CDS cpxA NC_011601.1 4418728 4420101 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4418728..4420101) Escherichia coli O127:H6 str. E2348/69 7064839 YP_002331675.1 CDS cpxR NC_011601.1 4420098 4420796 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4420098..4420796) Escherichia coli O127:H6 str. E2348/69 7062838 YP_002331676.1 CDS cpxP NC_011601.1 4420946 4421446 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4420946..4421446 Escherichia coli O127:H6 str. E2348/69 7062840 YP_002331677.1 CDS fieF NC_011601.1 4421594 4422496 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4421594..4422496 Escherichia coli O127:H6 str. E2348/69 7062839 YP_002331678.1 CDS pfkA NC_011601.1 4422677 4423639 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4422677..4423639 Escherichia coli O127:H6 str. E2348/69 7062118 YP_002331679.1 CDS sbp NC_011601.1 4423959 4424948 D sulfate transporter subunit 4423959..4424948 Escherichia coli O127:H6 str. E2348/69 7060706 YP_002331680.1 CDS cdh NC_011601.1 4425055 4425810 D CDP-diacylglycerol pyrophosphatase 4425055..4425810 Escherichia coli O127:H6 str. E2348/69 7065337 YP_002331681.1 CDS tpiA NC_011601.1 4425865 4426632 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4425865..4426632) Escherichia coli O127:H6 str. E2348/69 7064342 YP_002331682.1 CDS yiiQ NC_011601.1 4426740 4427339 R hypothetical protein complement(4426740..4427339) Escherichia coli O127:H6 str. E2348/69 7062229 YP_002331683.1 CDS yiiR NC_011601.1 4427440 4427880 D hypothetical protein 4427440..4427880 Escherichia coli O127:H6 str. E2348/69 7064840 YP_002331684.1 CDS yiiS NC_011601.1 4428092 4428391 D hypothetical protein 4428092..4428391 Escherichia coli O127:H6 str. E2348/69 7064841 YP_002331685.1 CDS uspD NC_011601.1 4428418 4428846 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4428418..4428846 Escherichia coli O127:H6 str. E2348/69 7064842 YP_002331686.1 CDS fpr NC_011601.1 4428851 4429597 R ferredoxin-NADP reductase complement(4428851..4429597) Escherichia coli O127:H6 str. E2348/69 7062335 YP_002331687.1 CDS glpX NC_011601.1 4429694 4430704 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4429694..4430704) Escherichia coli O127:H6 str. E2348/69 7061947 YP_002331688.1 CDS glpK NC_011601.1 4430875 4432383 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4430875..4432383) Escherichia coli O127:H6 str. E2348/69 7061703 YP_002331689.1 CDS glpF NC_011601.1 4432406 4433251 R glycerol facilitator complement(4432406..4433251) Escherichia coli O127:H6 str. E2348/69 7061699 YP_002331690.1 CDS yiiU NC_011601.1 4433676 4433921 D hypothetical protein 4433676..4433921 Escherichia coli O127:H6 str. E2348/69 7061697 YP_002331691.1 CDS rraA NC_011601.1 4434006 4434491 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4434006..4434491) Escherichia coli O127:H6 str. E2348/69 7064070 YP_002331692.1 CDS menA NC_011601.1 4434584 4435510 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4434584..4435510) Escherichia coli O127:H6 str. E2348/69 7061894 YP_002331693.1 CDS hslU NC_011601.1 4435577 4436908 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4435577..4436908) Escherichia coli O127:H6 str. E2348/69 7063748 YP_002331694.1 CDS hslV NC_011601.1 4436918 4437448 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4436918..4437448) Escherichia coli O127:H6 str. E2348/69 7062185 YP_002331695.1 CDS ftsN NC_011601.1 4437541 4438425 R 25 aa deleted; cell division protein FtsN complement(4437541..4438425) Escherichia coli O127:H6 str. E2348/69 7062186 YP_002331696.1 CDS cytR NC_011601.1 4438517 4439542 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4438517..4439542) Escherichia coli O127:H6 str. E2348/69 7061587 YP_002331697.1 CDS priA NC_011601.1 4439698 4441896 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4439698..4441896) Escherichia coli O127:H6 str. E2348/69 7065211 YP_002331698.1 CDS rpmE NC_011601.1 4442099 4442311 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4442099..4442311 Escherichia coli O127:H6 str. E2348/69 7061288 YP_002331699.1 CDS yiiX NC_011601.1 4442372 4442980 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4442372..4442980) Escherichia coli O127:H6 str. E2348/69 7061857 YP_002331700.1 CDS metJ NC_011601.1 4443040 4443357 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4443040..4443357) Escherichia coli O127:H6 str. E2348/69 7064071 YP_002331701.1 CDS metB NC_011601.1 4443634 4444794 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4443634..4444794 Escherichia coli O127:H6 str. E2348/69 7063764 YP_002331702.1 CDS metL NC_011601.1 4444797 4447229 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4444797..4447229 Escherichia coli O127:H6 str. E2348/69 7063757 YP_002331703.1 CDS E2348C_4245 NC_011601.1 4447447 4448307 R nucleoside-specific channel-forming protein Tsx complement(4447447..4448307) Escherichia coli O127:H6 str. E2348/69 7063766 YP_002331704.1 CDS E2348C_4246 NC_011601.1 4448384 4450003 R 5'-nucleotidase/2', 3'-cyclic phosphodiesterase complement(4448384..4450003) Escherichia coli O127:H6 str. E2348/69 7065109 YP_002331705.1 CDS E2348C_4247 NC_011601.1 4450044 4451597 R 5'-nucleotidase complement(4450044..4451597) Escherichia coli O127:H6 str. E2348/69 7065110 YP_002331706.1 CDS E2348C_4248 NC_011601.1 4451827 4452951 R hypothetical protein complement(4451827..4452951) Escherichia coli O127:H6 str. E2348/69 7065111 YP_002331707.1 CDS E2348C_4249 NC_011601.1 4453084 4454637 D 5'-nucleotidase/2', 3'-cyclic phosphodiesterase 4453084..4454637 Escherichia coli O127:H6 str. E2348/69 7065112 YP_002331708.1 CDS metF NC_011601.1 4455019 4455909 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4455019..4455909 Escherichia coli O127:H6 str. E2348/69 7065113 YP_002331709.1 CDS katG NC_011601.1 4456238 4458418 D catalase/hydroperoxidase HPI (I) 4456238..4458418 Escherichia coli O127:H6 str. E2348/69 7063760 YP_002331710.1 CDS yijE NC_011601.1 4458512 4459417 D permease 4458512..4459417 Escherichia coli O127:H6 str. E2348/69 7063564 YP_002331711.1 CDS yijF NC_011601.1 4459444 4460061 R hypothetical protein complement(4459444..4460061) Escherichia coli O127:H6 str. E2348/69 7064073 YP_002331712.1 CDS E2348C_4254 NC_011601.1 4460258 4460779 D transposase Orf1 of IS1397 4460258..4460779 Escherichia coli O127:H6 str. E2348/69 7061133 YP_002331713.1 CDS E2348C_4256 NC_011601.1 4461603 4462679 D transposase of ISEc21 4461603..4462679 Escherichia coli O127:H6 str. E2348/69 7061134 YP_002331714.1 CDS gldA NC_011601.1 4463144 4464247 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4463144..4464247) Escherichia coli O127:H6 str. E2348/69 7065115 YP_002331715.1 CDS fsaB NC_011601.1 4464258 4464920 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4464258..4464920) Escherichia coli O127:H6 str. E2348/69 7061665 YP_002331716.1 CDS ptsA NC_011601.1 4464932 4467433 R fused PTS enzymes: Hpr component/enzyme I component/enzyme IIA component complement(4464932..4467433) Escherichia coli O127:H6 str. E2348/69 7061974 YP_002331717.1 CDS frwC NC_011601.1 4467742 4468821 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4467742..4468821 Escherichia coli O127:H6 str. E2348/69 7061337 YP_002331718.1 CDS frwB NC_011601.1 4468836 4469156 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4468836..4469156 Escherichia coli O127:H6 str. E2348/69 7061968 YP_002331719.1 CDS pflD NC_011601.1 4469207 4471504 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4469207..4471504 Escherichia coli O127:H6 str. E2348/69 7061967 YP_002331720.1 CDS pflC NC_011601.1 4471470 4472348 D pyruvate formate lyase II activase 4471470..4472348 Escherichia coli O127:H6 str. E2348/69 7060711 YP_002331721.1 CDS frwD NC_011601.1 4472350 4472691 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4472350..4472691 Escherichia coli O127:H6 str. E2348/69 7060710 YP_002331722.1 CDS yijO NC_011601.1 4472678 4473529 R DNA-binding transcriptional regulator complement(4472678..4473529) Escherichia coli O127:H6 str. E2348/69 7061969 YP_002331723.1 CDS yijP NC_011601.1 4473755 4475488 R hypothetical protein complement(4473755..4475488) Escherichia coli O127:H6 str. E2348/69 7064074 YP_002331724.1 CDS ppc NC_011601.1 4475671 4478322 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4475671..4478322) Escherichia coli O127:H6 str. E2348/69 7064075 YP_002331725.1 CDS argE NC_011601.1 4478624 4479775 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4478624..4479775) Escherichia coli O127:H6 str. E2348/69 7061263 YP_002331726.1 CDS argC NC_011601.1 4479929 4480933 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4479929..4480933 Escherichia coli O127:H6 str. E2348/69 7061369 YP_002331727.1 CDS argB NC_011601.1 4480944 4481717 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4480944..4481717 Escherichia coli O127:H6 str. E2348/69 7061367 YP_002331728.1 CDS argH NC_011601.1 4481778 4483151 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4481778..4483151 Escherichia coli O127:H6 str. E2348/69 7061366 YP_002331729.1 CDS E2348C_4273 NC_011601.1 4483649 4484863 D dehydratase 4483649..4484863 Escherichia coli O127:H6 str. E2348/69 7061371 YP_002331730.1 CDS E2348C_4274 NC_011601.1 4484930 4486213 D transporter 4484930..4486213 Escherichia coli O127:H6 str. E2348/69 7065116 YP_002331731.1 CDS oxyR NC_011601.1 4486465 4487382 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4486465..4487382 Escherichia coli O127:H6 str. E2348/69 7062898 YP_002331732.1 CDS sthA NC_011601.1 4487365 4488765 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4487365..4488765) Escherichia coli O127:H6 str. E2348/69 7062897 YP_002331733.1 CDS E2348C_4277 NC_011601.1 4489095 4490261 D amino acid amidohydrolase 4489095..4490261 Escherichia coli O127:H6 str. E2348/69 7062775 YP_002331734.1 CDS E2348C_4278 NC_011601.1 4490304 4491620 D membrane transport/symporter protein 4490304..4491620 Escherichia coli O127:H6 str. E2348/69 7065118 YP_002331735.1 CDS fabR NC_011601.1 4491670 4492374 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4491670..4492374 Escherichia coli O127:H6 str. E2348/69 7065119 YP_002331736.1 CDS yijD NC_011601.1 4492374 4492733 D hypothetical protein 4492374..4492733 Escherichia coli O127:H6 str. E2348/69 7062069 YP_002331737.1 CDS trmA NC_011601.1 4492773 4493873 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4492773..4493873) Escherichia coli O127:H6 str. E2348/69 7064072 YP_002331738.1 CDS btuB NC_011601.1 4494242 4496125 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4494242..4496125 Escherichia coli O127:H6 str. E2348/69 7061157 YP_002331739.1 CDS murI NC_011601.1 4496070 4496927 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4496070..4496927 Escherichia coli O127:H6 str. E2348/69 7062534 YP_002331740.1 CDS murB NC_011601.1 4502453 4503481 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4502453..4503481 Escherichia coli O127:H6 str. E2348/69 7064526 YP_002331741.1 CDS birA NC_011601.1 4503478 4504443 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4503478..4504443 Escherichia coli O127:H6 str. E2348/69 7060888 YP_002331742.1 CDS coaA NC_011601.1 4504472 4505422 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4504472..4505422) Escherichia coli O127:H6 str. E2348/69 7062526 YP_002331743.1 CDS tufB NC_011601.1 4506340 4507524 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4506340..4507524 Escherichia coli O127:H6 str. E2348/69 7061798 YP_002331744.1 CDS secE NC_011601.1 4507754 4508137 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4507754..4508137 Escherichia coli O127:H6 str. E2348/69 7062280 YP_002331745.1 CDS nusG NC_011601.1 4508139 4508684 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4508139..4508684 Escherichia coli O127:H6 str. E2348/69 7065355 YP_002331746.1 CDS rplK NC_011601.1 4508843 4509271 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4508843..4509271 Escherichia coli O127:H6 str. E2348/69 7062870 YP_002331747.1 CDS rplA NC_011601.1 4509275 4509979 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4509275..4509979 Escherichia coli O127:H6 str. E2348/69 7061838 YP_002331748.1 CDS rplJ NC_011601.1 4510271 4510768 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4510271..4510768 Escherichia coli O127:H6 str. E2348/69 7061830 YP_002331749.1 CDS rplL NC_011601.1 4510835 4511200 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4510835..4511200 Escherichia coli O127:H6 str. E2348/69 7061837 YP_002331750.1 CDS rpoB NC_011601.1 4511520 4515548 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4511520..4515548 Escherichia coli O127:H6 str. E2348/69 7061158 YP_002331751.1 CDS rpoC NC_011601.1 4515625 4519848 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4515625..4519848 Escherichia coli O127:H6 str. E2348/69 7061864 YP_002331752.1 CDS thiH NC_011601.1 4520090 4521223 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4520090..4521223) Escherichia coli O127:H6 str. E2348/69 7061865 YP_002331753.1 CDS thiG NC_011601.1 4521220 4521990 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4521220..4521990) Escherichia coli O127:H6 str. E2348/69 7061785 YP_002331754.1 CDS thiS NC_011601.1 4521992 4522192 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4521992..4522192) Escherichia coli O127:H6 str. E2348/69 7061784 YP_002331755.1 CDS thiF NC_011601.1 4522176 4522931 R thiamin (thiazole moiety) biosynthesis protein ThiF complement(4522176..4522931) Escherichia coli O127:H6 str. E2348/69 7061792 YP_002331756.1 CDS thiE NC_011601.1 4522924 4523559 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4522924..4523559) Escherichia coli O127:H6 str. E2348/69 7061783 YP_002331757.1 CDS thiC NC_011601.1 4523559 4525454 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4523559..4525454) Escherichia coli O127:H6 str. E2348/69 7061782 YP_002331758.1 CDS rsd NC_011601.1 4525687 4526163 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4525687..4526163) Escherichia coli O127:H6 str. E2348/69 7061159 YP_002331759.1 CDS nudC NC_011601.1 4526258 4527031 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4526258..4527031 Escherichia coli O127:H6 str. E2348/69 7064549 YP_002331760.1 CDS hemE NC_011601.1 4527071 4528135 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4527071..4528135 Escherichia coli O127:H6 str. E2348/69 7065428 YP_002331761.1 CDS nfi NC_011601.1 4528145 4528816 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4528145..4528816 Escherichia coli O127:H6 str. E2348/69 7064295 YP_002331762.1 CDS yjaG NC_011601.1 4528859 4529449 D hypothetical protein 4528859..4529449 Escherichia coli O127:H6 str. E2348/69 7065381 YP_002331763.1 CDS hupA NC_011601.1 4529636 4529908 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4529636..4529908 Escherichia coli O127:H6 str. E2348/69 7064078 YP_002331764.1 CDS yjaH NC_011601.1 4529921 4530616 D hypothetical protein 4529921..4530616 Escherichia coli O127:H6 str. E2348/69 7062193 YP_002331765.1 CDS zraP NC_011601.1 4530618 4531043 R zinc resistance protein complement(4530618..4531043) Escherichia coli O127:H6 str. E2348/69 7064079 YP_002331766.1 CDS zraS NC_011601.1 4531281 4532657 D sensor protein ZraS 4531281..4532657 Escherichia coli O127:H6 str. E2348/69 7062538 YP_002331767.1 CDS zraR NC_011601.1 4532654 4533979 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4532654..4533979 Escherichia coli O127:H6 str. E2348/69 7062540 YP_002331768.1 CDS purD NC_011601.1 4533976 4535265 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4533976..4535265) Escherichia coli O127:H6 str. E2348/69 7062539 YP_002331769.1 CDS purH NC_011601.1 4535277 4536866 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4535277..4536866) Escherichia coli O127:H6 str. E2348/69 7063914 YP_002331770.1 CDS yjaA NC_011601.1 4542667 4543050 D hypothetical protein 4542667..4543050 Escherichia coli O127:H6 str. E2348/69 7064529 YP_002331771.1 CDS yjaB NC_011601.1 4543114 4543557 R hypothetical protein complement(4543114..4543557) Escherichia coli O127:H6 str. E2348/69 7064076 YP_002331772.1 CDS metA NC_011601.1 4543714 4544643 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4543714..4544643 Escherichia coli O127:H6 str. E2348/69 7064077 YP_002331773.1 CDS aceB NC_011601.1 4544912 4546513 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4544912..4546513 Escherichia coli O127:H6 str. E2348/69 7063756 YP_002331774.1 CDS aceA NC_011601.1 4546543 4547847 D isocitrate lyase 4546543..4547847 Escherichia coli O127:H6 str. E2348/69 7062385 YP_002331775.1 CDS aceK NC_011601.1 4547972 4549696 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4547972..4549696 Escherichia coli O127:H6 str. E2348/69 7062384 YP_002331776.1 CDS iclR NC_011601.1 4549713 4550537 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4549713..4550537) Escherichia coli O127:H6 str. E2348/69 7062388 YP_002331777.1 CDS metH NC_011601.1 4550737 4554420 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4550737..4554420 Escherichia coli O127:H6 str. E2348/69 7063518 YP_002331778.1 CDS E2348C_4322 NC_011601.1 4554474 4554800 D hypothetical protein 4554474..4554800 Escherichia coli O127:H6 str. E2348/69 7063762 YP_002331779.1 CDS E2348C_4323 NC_011601.1 4554843 4555292 D hypothetical protein 4554843..4555292 Escherichia coli O127:H6 str. E2348/69 7065120 YP_002331780.1 CDS yjbB NC_011601.1 4555463 4557094 D transporter 4555463..4557094 Escherichia coli O127:H6 str. E2348/69 7065121 YP_002331781.1 CDS E2348C_4325 NC_011601.1 4557180 4557701 D transposase Orf1 of IS1397 4557180..4557701 Escherichia coli O127:H6 str. E2348/69 7061136 YP_002331782.1 CDS E2348C_4327 NC_011601.1 4558522 4559598 D transposase of ISEc21 4558522..4559598 Escherichia coli O127:H6 str. E2348/69 7061137 YP_002331783.1 CDS pepE NC_011601.1 4559990 4560679 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4559990..4560679) Escherichia coli O127:H6 str. E2348/69 7065123 YP_002331784.1 CDS E2348C_4330 NC_011601.1 4561060 4562289 R L-sorbose 1-phosphate dehydrogenase complement(4561060..4562289) Escherichia coli O127:H6 str. E2348/69 7060701 YP_002331785.1 CDS E2348C_4331 NC_011601.1 4562341 4563165 R sorbose-permease PTS system IID component complement(4562341..4563165) Escherichia coli O127:H6 str. E2348/69 7065124 YP_002331786.1 CDS E2348C_4332 NC_011601.1 4563176 4563973 R sorbose-permease PTS system IIC component complement(4563176..4563973) Escherichia coli O127:H6 str. E2348/69 7065125 YP_002331787.1 CDS E2348C_4333 NC_011601.1 4564039 4564533 R sorbose-permease PTS system IIB component complement(4564039..4564533) Escherichia coli O127:H6 str. E2348/69 7065126 YP_002331788.1 CDS E2348C_4334 NC_011601.1 4564533 4564940 R sorbose-permease PTS system IIA component complement(4564533..4564940) Escherichia coli O127:H6 str. E2348/69 7065127 YP_002331789.1 CDS E2348C_4335 NC_011601.1 4564950 4565756 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4564950..4565756) Escherichia coli O127:H6 str. E2348/69 7065128 YP_002331790.1 CDS E2348C_4336 NC_011601.1 4565826 4566773 R sor-operon regulator complement(4565826..4566773) Escherichia coli O127:H6 str. E2348/69 7065129 YP_002331791.1 CDS rluF NC_011601.1 4567121 4567993 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4567121..4567993 Escherichia coli O127:H6 str. E2348/69 7065130 YP_002331792.1 CDS pagB NC_011601.1 4567994 4568266 R hypothetical protein complement(4567994..4568266) Escherichia coli O127:H6 str. E2348/69 7060843 YP_002331793.1 CDS lysC NC_011601.1 4568520 4569869 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase complement(4568520..4569869) Escherichia coli O127:H6 str. E2348/69 7062903 YP_002331794.1 CDS pgi NC_011601.1 4570394 4572043 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4570394..4572043 Escherichia coli O127:H6 str. E2348/69 7061160 YP_002331795.1 CDS yjbE NC_011601.1 4572397 4572639 D hypothetical protein 4572397..4572639 Escherichia coli O127:H6 str. E2348/69 7060713 YP_002331796.1 CDS yjbF NC_011601.1 4572753 4573391 D lipoprotein 4572753..4573391 Escherichia coli O127:H6 str. E2348/69 7064080 YP_002331797.1 CDS yjbG NC_011601.1 4573388 4574125 D hypothetical protein 4573388..4574125 Escherichia coli O127:H6 str. E2348/69 7064081 YP_002331798.1 CDS yjbH NC_011601.1 4574125 4576221 D porin 4574125..4576221 Escherichia coli O127:H6 str. E2348/69 7064082 YP_002331799.1 CDS yjbT NC_011601.1 4576268 4576546 R hypothetical protein complement(4576268..4576546) Escherichia coli O127:H6 str. E2348/69 7064083 YP_002331800.1 CDS psiE NC_011601.1 4576761 4577171 D phosphate-starvation-inducible protein PsiE 4576761..4577171 Escherichia coli O127:H6 str. E2348/69 7064087 YP_002331801.1 CDS malG NC_011601.1 4577265 4578155 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4577265..4578155) Escherichia coli O127:H6 str. E2348/69 7061316 YP_002331802.1 CDS malF NC_011601.1 4578170 4579714 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4578170..4579714) Escherichia coli O127:H6 str. E2348/69 7065272 YP_002331803.1 CDS malE NC_011601.1 4579868 4581058 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4579868..4581058) Escherichia coli O127:H6 str. E2348/69 7065271 YP_002331804.1 CDS malK NC_011601.1 4581423 4582538 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4581423..4582538 Escherichia coli O127:H6 str. E2348/69 7065270 YP_002331805.1 CDS lamB NC_011601.1 4582610 4583950 D porin involved in the transport of maltose and maltodextrins; maltoporin 4582610..4583950 Escherichia coli O127:H6 str. E2348/69 7065274 YP_002331806.1 CDS E2348C_4352 NC_011601.1 4584135 4585508 R transposase of ISEc13 complement(4584135..4585508) Escherichia coli O127:H6 str. E2348/69 7061139 YP_002331807.1 CDS malM NC_011601.1 4585740 4586675 D maltose regulon periplasmic protein 4585740..4586675 Escherichia coli O127:H6 str. E2348/69 7065131 YP_002331808.1 CDS ubiC NC_011601.1 4586854 4587351 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4586854..4587351 Escherichia coli O127:H6 str. E2348/69 7065275 YP_002331809.1 CDS ubiA NC_011601.1 4587364 4588236 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4587364..4588236 Escherichia coli O127:H6 str. E2348/69 7062292 YP_002331810.1 CDS plsB NC_011601.1 4588391 4590814 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4588391..4590814) Escherichia coli O127:H6 str. E2348/69 7062290 YP_002331811.1 CDS dgkA NC_011601.1 4590985 4591353 D diacylglycerol kinase 4590985..4591353 Escherichia coli O127:H6 str. E2348/69 7060756 YP_002331812.1 CDS lexA NC_011601.1 4591463 4592071 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4591463..4592071 Escherichia coli O127:H6 str. E2348/69 7065014 YP_002331813.1 CDS dinF NC_011601.1 4592090 4593469 D DNA-damage-inducible SOS response protein 4592090..4593469 Escherichia coli O127:H6 str. E2348/69 7061537 YP_002331814.1 CDS yjbJ NC_011601.1 4593585 4593794 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4593585..4593794 Escherichia coli O127:H6 str. E2348/69 7065030 YP_002331815.1 CDS zur NC_011601.1 4593836 4594351 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4593836..4594351) Escherichia coli O127:H6 str. E2348/69 7064084 YP_002331816.1 CDS dusA NC_011601.1 4594507 4595502 D tRNA-dihydrouridine synthase A 4594507..4595502 Escherichia coli O127:H6 str. E2348/69 7062542 YP_002331817.1 CDS pspG NC_011601.1 4595636 4595878 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4595636..4595878 Escherichia coli O127:H6 str. E2348/69 7065071 YP_002331818.1 CDS dnaB NC_011601.1 4597114 4598529 D unwinds double stranded DNA; replicative DNA helicase 4597114..4598529 Escherichia coli O127:H6 str. E2348/69 7063938 YP_002331819.1 CDS alr NC_011601.1 4598582 4599661 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4598582..4599661 Escherichia coli O127:H6 str. E2348/69 7065045 YP_002331820.1 CDS E2348C_4367 NC_011601.1 4599684 4600241 D nicotinamide mononucleotide transporter 4599684..4600241 Escherichia coli O127:H6 str. E2348/69 7062445 YP_002331821.1 CDS E2348C_4368 NC_011601.1 4600238 4601242 D NadR-like protein 4600238..4601242 Escherichia coli O127:H6 str. E2348/69 7065132 YP_002331822.1 CDS tyrB NC_011601.1 4601324 4602517 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4601324..4602517 Escherichia coli O127:H6 str. E2348/69 7065133 YP_002331823.1 CDS sucA NC_011601.1 4602699 4605443 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4602699..4605443 Escherichia coli O127:H6 str. E2348/69 7062284 YP_002331824.1 CDS E2348C_4371 NC_011601.1 4605476 4606630 D dihydrolipoyltranssuccinase 4605476..4606630 Escherichia coli O127:H6 str. E2348/69 7065134 YP_002331825.1 CDS E2348C_4372 NC_011601.1 4606642 4608060 D dihydrolipoamide dehydrogenase 4606642..4608060 Escherichia coli O127:H6 str. E2348/69 7065135 YP_002331826.1 CDS E2348C_4373 NC_011601.1 4608082 4609251 D succinyl-CoA synthetase, beta subunit 4608082..4609251 Escherichia coli O127:H6 str. E2348/69 7065136 YP_002331827.1 CDS E2348C_4374 NC_011601.1 4609264 4610136 D succinyl-CoA synthetase subunit alpha 4609264..4610136 Escherichia coli O127:H6 str. E2348/69 7065137 YP_002331828.1 CDS E2348C_4375 NC_011601.1 4610348 4611847 D di-and tricarboxylate transporter 4610348..4611847 Escherichia coli O127:H6 str. E2348/69 7065138 YP_002331829.1 CDS E2348C_4376 NC_011601.1 4611859 4612932 D dehydrogenase 4611859..4612932 Escherichia coli O127:H6 str. E2348/69 7065139 YP_002331830.1 CDS E2348C_4377 NC_011601.1 4612921 4614279 R response regulator in two-component system complement(4612921..4614279) Escherichia coli O127:H6 str. E2348/69 7065140 YP_002331831.1 CDS E2348C_4378 NC_011601.1 4614272 4616092 R sensory histidine kinase in two-component system complement(4614272..4616092) Escherichia coli O127:H6 str. E2348/69 7065141 YP_002331832.1 CDS aphA NC_011601.1 4616369 4617082 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4616369..4617082 Escherichia coli O127:H6 str. E2348/69 7065142 YP_002331833.1 CDS yjbQ NC_011601.1 4617193 4617609 D hypothetical protein 4617193..4617609 Escherichia coli O127:H6 str. E2348/69 7061350 YP_002331834.1 CDS yjbR NC_011601.1 4617613 4617969 D hypothetical protein 4617613..4617969 Escherichia coli O127:H6 str. E2348/69 7064085 YP_002331835.1 CDS uvrA NC_011601.1 4618004 4620826 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4618004..4620826) Escherichia coli O127:H6 str. E2348/69 7064086 YP_002331836.1 CDS ssb NC_011601.1 4621081 4621617 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4621081..4621617 Escherichia coli O127:H6 str. E2348/69 7062340 YP_002331837.1 CDS yjcB NC_011601.1 4621716 4621997 R hypothetical protein complement(4621716..4621997) Escherichia coli O127:H6 str. E2348/69 7062760 YP_002331838.1 CDS yjcC NC_011601.1 4622426 4623979 D signal transduction protein (EAL domain containing protein) 4622426..4623979 Escherichia coli O127:H6 str. E2348/69 7064088 YP_002331839.1 CDS soxS NC_011601.1 4624015 4624338 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4624015..4624338) Escherichia coli O127:H6 str. E2348/69 7064089 YP_002331840.1 CDS soxR NC_011601.1 4624424 4624888 D DNA-binding transcriptional dual regulator, Fe-Scenter for redox-sensing 4624424..4624888 Escherichia coli O127:H6 str. E2348/69 7062739 YP_002331841.1 CDS yjcD NC_011601.1 4625435 4626784 D permease 4625435..4626784 Escherichia coli O127:H6 str. E2348/69 7065325 YP_002331842.1 CDS yjcE NC_011601.1 4626935 4628584 D cation/proton antiporter 4626935..4628584 Escherichia coli O127:H6 str. E2348/69 7064090 YP_002331843.1 CDS actP NC_011601.1 4628667 4630316 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4628667..4630316) Escherichia coli O127:H6 str. E2348/69 7064091 YP_002331844.1 CDS yjcH NC_011601.1 4630313 4630627 R inner membrane protein involved in acetate transport complement(4630313..4630627) Escherichia coli O127:H6 str. E2348/69 7062403 YP_002331845.1 CDS acs NC_011601.1 4630919 4632877 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4630919..4632877) Escherichia coli O127:H6 str. E2348/69 7064092 YP_002331846.1 CDS nrfA NC_011601.1 4633269 4634705 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4633269..4634705 Escherichia coli O127:H6 str. E2348/69 7062402 YP_002331847.1 CDS nrfB NC_011601.1 4634750 4635316 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4634750..4635316 Escherichia coli O127:H6 str. E2348/69 7065418 YP_002331848.1 CDS nrfC NC_011601.1 4635313 4635984 D formate-dependent nitrite reductase NrfC, 4Fe4S subunit 4635313..4635984 Escherichia coli O127:H6 str. E2348/69 7065419 YP_002331849.1 CDS nrfD NC_011601.1 4635981 4636937 D formate-dependent nitrite reductase complex subunit NrfD 4635981..4636937 Escherichia coli O127:H6 str. E2348/69 7065420 YP_002331850.1 CDS nrfE NC_011601.1 4637017 4638675 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4637017..4638675 Escherichia coli O127:H6 str. E2348/69 7065421 YP_002331851.1 CDS nrfF NC_011601.1 4638668 4639051 D formate-dependent nitrite reductase complex subunit NrfF 4638668..4639051 Escherichia coli O127:H6 str. E2348/69 7065422 YP_002331852.1 CDS nrfG NC_011601.1 4639048 4639644 D formate-dependent nitrite reductase complex subunit NrfG 4639048..4639644 Escherichia coli O127:H6 str. E2348/69 7065423 YP_002331853.1 CDS gltP NC_011601.1 4639987 4641300 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4639987..4641300 Escherichia coli O127:H6 str. E2348/69 7065424 YP_002331854.1 CDS yjcO NC_011601.1 4641378 4642067 R hypothetical protein complement(4641378..4642067) Escherichia coli O127:H6 str. E2348/69 7061711 YP_002331855.1 CDS E2348C_4402 NC_011601.1 4642178 4642882 R ABC transporter ATP-binding protein complement(4642178..4642882) Escherichia coli O127:H6 str. E2348/69 7064093 YP_002331856.1 CDS E2348C_4403 NC_011601.1 4642869 4643705 R ABC transporter ATP-binding protein complement(4642869..4643705) Escherichia coli O127:H6 str. E2348/69 7065143 YP_002331857.1 CDS E2348C_4404 NC_011601.1 4643698 4644531 R ABC transporter permease complement(4643698..4644531) Escherichia coli O127:H6 str. E2348/69 7065144 YP_002331858.1 CDS E2348C_4405 NC_011601.1 4644531 4645580 R ABC transporter permease complement(4644531..4645580) Escherichia coli O127:H6 str. E2348/69 7065145 YP_002331859.1 CDS E2348C_4406 NC_011601.1 4645680 4647248 R dipeptide ABC transporter periplasmic protein complement(4645680..4647248) Escherichia coli O127:H6 str. E2348/69 7065146 YP_002331860.1 CDS fdhF NC_011601.1 4647623 4649770 R selenocysteine (Sec=>U); formate dehydrogenase-H, selenopolypeptide subunit complement(4647623..4649770) Escherichia coli O127:H6 str. E2348/69 7065147 YP_002331861.1 CDS mdtP NC_011601.1 4649968 4651434 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(4649968..4651434) Escherichia coli O127:H6 str. E2348/69 7062087 YP_002331862.1 CDS mdtO NC_011601.1 4651431 4653482 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4651431..4653482) Escherichia coli O127:H6 str. E2348/69 7065320 YP_002331863.1 CDS mdtN NC_011601.1 4653482 4654513 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4653482..4654513) Escherichia coli O127:H6 str. E2348/69 7065319 YP_002331864.1 CDS ytcA NC_011601.1 4654532 4654807 R hypothetical protein complement(4654532..4654807) Escherichia coli O127:H6 str. E2348/69 7065318 YP_002331865.1 CDS yjcS NC_011601.1 4655016 4657001 R alkyl sulfatase complement(4655016..4657001) Escherichia coli O127:H6 str. E2348/69 7063239 YP_002331866.1 CDS alsK NC_011601.1 4657274 4658203 R D-allose kinase complement(4657274..4658203) Escherichia coli O127:H6 str. E2348/69 7064094 YP_002331867.1 CDS alsE NC_011601.1 4658187 4658882 R allulose-6-phosphate 3-epimerase complement(4658187..4658882) Escherichia coli O127:H6 str. E2348/69 7062450 YP_002331868.1 CDS alsC NC_011601.1 4658893 4659873 R D-allose transporter subunit complement(4658893..4659873) Escherichia coli O127:H6 str. E2348/69 7062449 YP_002331869.1 CDS alsA NC_011601.1 4659852 4661384 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4659852..4661384) Escherichia coli O127:H6 str. E2348/69 7062448 YP_002331870.1 CDS alsB NC_011601.1 4661512 4662447 R D-allose transporter subunit complement(4661512..4662447) Escherichia coli O127:H6 str. E2348/69 7062446 YP_002331871.1 CDS rpiR NC_011601.1 4662506 4663396 R involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR complement(4662506..4663396) Escherichia coli O127:H6 str. E2348/69 7062447 YP_002331872.1 CDS rpiB NC_011601.1 4663750 4664199 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4663750..4664199 Escherichia coli O127:H6 str. E2348/69 7061829 YP_002331873.1 CDS yjdP NC_011601.1 4664268 4664597 D hypothetical protein 4664268..4664597 Escherichia coli O127:H6 str. E2348/69 7061828 YP_002331874.1 CDS phnP NC_011601.1 4664632 4665390 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4664632..4665390) Escherichia coli O127:H6 str. E2348/69 7064104 YP_002331875.1 CDS phnO NC_011601.1 4665392 4665826 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4665392..4665826) Escherichia coli O127:H6 str. E2348/69 7060741 YP_002331876.1 CDS phnN NC_011601.1 4665813 4666370 R ribose 1,5-bisphosphokinase complement(4665813..4666370) Escherichia coli O127:H6 str. E2348/69 7060740 YP_002331877.1 CDS phnM NC_011601.1 4666370 4667506 R carbon-phosphorus lyase complex subunit PhnM complement(4666370..4667506) Escherichia coli O127:H6 str. E2348/69 7060739 YP_002331878.1 CDS phnL NC_011601.1 4667503 4668183 R carbon-phosphorus lyase complex subunit PhnL complement(4667503..4668183) Escherichia coli O127:H6 str. E2348/69 7060738 YP_002331879.1 CDS phnK NC_011601.1 4668294 4669052 R phosphonate C-P lyase system protein PhnK complement(4668294..4669052) Escherichia coli O127:H6 str. E2348/69 7060737 YP_002331880.1 CDS phnJ NC_011601.1 4669049 4669894 R carbon-phosphorus lyase complex subunit PhnJ complement(4669049..4669894) Escherichia coli O127:H6 str. E2348/69 7060736 YP_002331881.1 CDS phnI NC_011601.1 4669887 4670951 R carbon-phosphorus lyase complex subunit PhnI complement(4669887..4670951) Escherichia coli O127:H6 str. E2348/69 7060735 YP_002331882.1 CDS phnH NC_011601.1 4670951 4671535 R carbon-phosphorus lyase complex subunit complement(4670951..4671535) Escherichia coli O127:H6 str. E2348/69 7060734 YP_002331883.1 CDS phnG NC_011601.1 4671532 4671984 R carbon-phosphorus lyase complex subunit PhnG complement(4671532..4671984) Escherichia coli O127:H6 str. E2348/69 7060733 YP_002331884.1 CDS phnF NC_011601.1 4671985 4672710 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4671985..4672710) Escherichia coli O127:H6 str. E2348/69 7060732 YP_002331885.1 CDS phnE NC_011601.1 4672731 4673564 R phosphonate/organophosphate ester transporter subunit PhnE, membrane component of ABC superfamily complement(4672731..4673564) Escherichia coli O127:H6 str. E2348/69 7060731 YP_002331886.1 CDS phnD NC_011601.1 4673616 4674632 R phosphonate/organophosphate ester transporter subunit complement(4673616..4674632) Escherichia coli O127:H6 str. E2348/69 7060730 YP_002331887.1 CDS phnC NC_011601.1 4674657 4675445 R phosphonate/organophosphate ester transporter subunit complement(4674657..4675445) Escherichia coli O127:H6 str. E2348/69 7060729 YP_002331888.1 CDS yjdN NC_011601.1 4675578 4676021 R hypothetical protein complement(4675578..4676021) Escherichia coli O127:H6 str. E2348/69 7060728 YP_002331889.1 CDS yjdM NC_011601.1 4676181 4676516 R hypothetical protein complement(4676181..4676516) Escherichia coli O127:H6 str. E2348/69 7064103 YP_002331890.1 CDS yjdA NC_011601.1 4676919 4679147 D hypothetical protein 4676919..4679147 Escherichia coli O127:H6 str. E2348/69 7064102 YP_002331891.1 CDS yjdZ NC_011601.1 4679144 4680022 D hypothetical protein 4679144..4680022 Escherichia coli O127:H6 str. E2348/69 7064095 YP_002331892.1 CDS proP NC_011601.1 4680286 4681788 D proline/glycine betaine transporter 4680286..4681788 Escherichia coli O127:H6 str. E2348/69 7064105 YP_002331893.1 CDS basS NC_011601.1 4681965 4683056 R sensor protein BasS/PmrB complement(4681965..4683056) Escherichia coli O127:H6 str. E2348/69 7061302 YP_002331894.1 CDS basR NC_011601.1 4683066 4683734 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4683066..4683734) Escherichia coli O127:H6 str. E2348/69 7062495 YP_002331895.1 CDS eptA NC_011601.1 4683731 4685374 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4683731..4685374) Escherichia coli O127:H6 str. E2348/69 7062494 YP_002331896.1 CDS adiC NC_011601.1 4685478 4686815 R arginine:agmatin antiporter complement(4685478..4686815) Escherichia coli O127:H6 str. E2348/69 7063863 YP_002331897.1 CDS adiY NC_011601.1 4686952 4687713 R DNA-binding transcriptional activator complement(4686952..4687713) Escherichia coli O127:H6 str. E2348/69 7062409 YP_002331898.1 CDS adiA NC_011601.1 4688037 4690307 R biodegradative arginine decarboxylase complement(4688037..4690307) Escherichia coli O127:H6 str. E2348/69 7062410 YP_002331899.1 CDS melR NC_011601.1 4690503 4691411 R DNA-binding transcriptional regulator MelR complement(4690503..4691411) Escherichia coli O127:H6 str. E2348/69 7062408 YP_002331900.1 CDS melA NC_011601.1 4691694 4693049 D alpha-galactosidase 4691694..4693049 Escherichia coli O127:H6 str. E2348/69 7065323 YP_002331901.1 CDS yjdF NC_011601.1 4693046 4693696 R hypothetical protein complement(4693046..4693696) Escherichia coli O127:H6 str. E2348/69 7065322 YP_002331902.1 CDS fumB NC_011601.1 4693819 4695465 R anaerobic class I fumarate hydratase (fumaraseB) complement(4693819..4695465) Escherichia coli O127:H6 str. E2348/69 7064097 YP_002331903.1 CDS dcuB NC_011601.1 4695543 4696883 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4695543..4696883) Escherichia coli O127:H6 str. E2348/69 7061601 YP_002331904.1 CDS dcuR NC_011601.1 4697454 4698173 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4697454..4698173) Escherichia coli O127:H6 str. E2348/69 7065232 YP_002331905.1 CDS dcuS NC_011601.1 4698170 4699801 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4698170..4699801) Escherichia coli O127:H6 str. E2348/69 7065234 YP_002331906.1 CDS yjdI NC_011601.1 4699982 4700212 D hypothetical protein 4699982..4700212 Escherichia coli O127:H6 str. E2348/69 7065235 YP_002331907.1 CDS yjdJ NC_011601.1 4700224 4700496 D acyltransferase with acyl-CoAN-acyltransferase domain 4700224..4700496 Escherichia coli O127:H6 str. E2348/69 7064098 YP_002331908.1 CDS yjdK NC_011601.1 4700724 4701020 D hypothetical protein 4700724..4701020 Escherichia coli O127:H6 str. E2348/69 7064099 YP_002331909.1 CDS lysU NC_011601.1 4701340 4702857 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4701340..4702857) Escherichia coli O127:H6 str. E2348/69 7064100 YP_002331910.1 CDS yjdL NC_011601.1 4703094 4704551 R transporter complement(4703094..4704551) Escherichia coli O127:H6 str. E2348/69 7065258 YP_002331911.1 CDS cadA NC_011601.1 4704610 4706757 R lysine decarboxylase 1 complement(4704610..4706757) Escherichia coli O127:H6 str. E2348/69 7064101 YP_002331912.1 CDS cadB NC_011601.1 4706837 4708171 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4706837..4708171) Escherichia coli O127:H6 str. E2348/69 7064313 YP_002331913.1 CDS yjdC NC_011601.1 4710874 4711449 R transcriptional regulator complement(4710874..4711449) Escherichia coli O127:H6 str. E2348/69 7060726 YP_002331914.1 CDS dipZ NC_011601.1 4711486 4713183 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4711486..4713183) Escherichia coli O127:H6 str. E2348/69 7064096 YP_002331915.1 CDS cutA NC_011601.1 4713159 4713497 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4713159..4713497) Escherichia coli O127:H6 str. E2348/69 7065034 YP_002331916.1 CDS dcuA NC_011601.1 4713612 4714913 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4713612..4714913) Escherichia coli O127:H6 str. E2348/69 7065175 YP_002331917.1 CDS aspA NC_011601.1 4715031 4716467 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4715031..4716467) Escherichia coli O127:H6 str. E2348/69 7065231 YP_002331918.1 CDS fxsA NC_011601.1 4716804 4717280 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4716804..4717280 Escherichia coli O127:H6 str. E2348/69 7063343 YP_002331919.1 CDS yjeH NC_011601.1 4717296 4718552 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(4717296..4718552) Escherichia coli O127:H6 str. E2348/69 7061605 YP_002331920.1 CDS groES NC_011601.1 4718828 4719121 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4718828..4719121 Escherichia coli O127:H6 str. E2348/69 7064108 YP_002331921.1 CDS groEL NC_011601.1 4719165 4720811 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4719165..4720811 Escherichia coli O127:H6 str. E2348/69 7064244 YP_002331922.1 CDS yjeI NC_011601.1 4720949 4721302 D hypothetical protein 4720949..4721302 Escherichia coli O127:H6 str. E2348/69 7064243 YP_002331923.1 CDS yjeJ NC_011601.1 4721352 4722221 R hypothetical protein complement(4721352..4722221) Escherichia coli O127:H6 str. E2348/69 7064109 YP_002331924.1 CDS yjeK NC_011601.1 4722456 4723484 R lysine aminomutase complement(4722456..4723484) Escherichia coli O127:H6 str. E2348/69 7064110 YP_002331925.1 CDS efp NC_011601.1 4723526 4724092 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4723526..4724092 Escherichia coli O127:H6 str. E2348/69 7064111 YP_002331926.1 CDS ecnA NC_011601.1 4724144 4724269 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4724144..4724269 Escherichia coli O127:H6 str. E2348/69 7063840 YP_002331927.1 CDS ecnB NC_011601.1 4724380 4724526 D entericidin B 4724380..4724526 Escherichia coli O127:H6 str. E2348/69 7065083 YP_002331928.1 CDS sugE NC_011601.1 4724702 4725019 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4724702..4725019 Escherichia coli O127:H6 str. E2348/69 7063749 YP_002331929.1 CDS blc NC_011601.1 4725016 4725549 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4725016..4725549) Escherichia coli O127:H6 str. E2348/69 7061741 YP_002331930.1 CDS ampC NC_011601.1 4725638 4726771 R beta-lactamase complement(4725638..4726771) Escherichia coli O127:H6 str. E2348/69 7062528 YP_002331931.1 CDS frdD NC_011601.1 4726834 4727193 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4726834..4727193) Escherichia coli O127:H6 str. E2348/69 7062456 YP_002331932.1 CDS frdC NC_011601.1 4727204 4727599 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4727204..4727599) Escherichia coli O127:H6 str. E2348/69 7061952 YP_002331933.1 CDS frdB NC_011601.1 4727610 4728344 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4727610..4728344) Escherichia coli O127:H6 str. E2348/69 7061951 YP_002331934.1 CDS frdA NC_011601.1 4728337 4730145 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4728337..4730145) Escherichia coli O127:H6 str. E2348/69 7061950 YP_002331935.1 CDS poxA NC_011601.1 4730470 4731447 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4730470..4731447 Escherichia coli O127:H6 str. E2348/69 7061949 YP_002331936.1 CDS yjeM NC_011601.1 4731666 4733168 D transporter 4731666..4733168 Escherichia coli O127:H6 str. E2348/69 7061260 YP_002331937.1 CDS yjeP NC_011601.1 4733319 4736642 R hypothetical protein complement(4733319..4736642) Escherichia coli O127:H6 str. E2348/69 7064112 YP_002331938.1 CDS psd NC_011601.1 4736664 4737632 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4736664..4737632) Escherichia coli O127:H6 str. E2348/69 7064113 YP_002331939.1 CDS rsgA NC_011601.1 4737729 4738781 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4737729..4738781) Escherichia coli O127:H6 str. E2348/69 7061315 YP_002331940.1 CDS orn NC_011601.1 4738876 4739421 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4738876..4739421 Escherichia coli O127:H6 str. E2348/69 7064554 YP_002331941.1 CDS yjeS NC_011601.1 4740321 4741460 R Fe-S electron transport protein complement(4740321..4741460) Escherichia coli O127:H6 str. E2348/69 7061728 YP_002331942.1 CDS yjeF NC_011601.1 4741459 4743006 D hypothetical protein 4741459..4743006 Escherichia coli O127:H6 str. E2348/69 7064114 YP_002331943.1 CDS yjeE NC_011601.1 4742978 4743439 D possibly involved in cell wall synthesis; ATPase 4742978..4743439 Escherichia coli O127:H6 str. E2348/69 7064107 YP_002331944.1 CDS amiB NC_011601.1 4743458 4744786 D N-acetylmuramoyl-L-alanine amidase 4743458..4744786 Escherichia coli O127:H6 str. E2348/69 7064106 YP_002331945.1 CDS mutL NC_011601.1 4744796 4746643 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4744796..4746643 Escherichia coli O127:H6 str. E2348/69 7062453 YP_002331946.1 CDS miaA NC_011601.1 4746636 4747586 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4746636..4747586 Escherichia coli O127:H6 str. E2348/69 7060898 YP_002331947.1 CDS hfq NC_011601.1 4747672 4747980 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4747672..4747980 Escherichia coli O127:H6 str. E2348/69 7063783 YP_002331948.1 CDS hflX NC_011601.1 4748056 4749336 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4748056..4749336 Escherichia coli O127:H6 str. E2348/69 7064309 YP_002331949.1 CDS hflK NC_011601.1 4749422 4750681 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4749422..4750681 Escherichia coli O127:H6 str. E2348/69 7064308 YP_002331950.1 CDS hflC NC_011601.1 4750684 4751688 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4750684..4751688 Escherichia coli O127:H6 str. E2348/69 7064307 YP_002331951.1 CDS yjeT NC_011601.1 4751770 4751967 D hypothetical protein 4751770..4751967 Escherichia coli O127:H6 str. E2348/69 7064305 YP_002331952.1 CDS purA NC_011601.1 4752071 4753369 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4752071..4753369 Escherichia coli O127:H6 str. E2348/69 7064115 YP_002331953.1 CDS nsrR NC_011601.1 4753574 4753999 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4753574..4753999 Escherichia coli O127:H6 str. E2348/69 7063911 YP_002331954.1 CDS rnr NC_011601.1 4754038 4756479 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4754038..4756479 Escherichia coli O127:H6 str. E2348/69 7065425 YP_002331955.1 CDS rlmB NC_011601.1 4756571 4757302 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4756571..4757302 Escherichia coli O127:H6 str. E2348/69 7061820 YP_002331956.1 CDS yjfI NC_011601.1 4757429 4757830 D hypothetical protein 4757429..4757830 Escherichia coli O127:H6 str. E2348/69 7060833 YP_002331957.1 CDS yjfJ NC_011601.1 4757849 4758547 D transcriptional regulator effectorprotein 4757849..4758547 Escherichia coli O127:H6 str. E2348/69 7064118 YP_002331958.1 CDS yjfK NC_011601.1 4758598 4759257 D hypothetical protein 4758598..4759257 Escherichia coli O127:H6 str. E2348/69 7064119 YP_002331959.1 CDS yjfL NC_011601.1 4759275 4759673 D hypothetical protein 4759275..4759673 Escherichia coli O127:H6 str. E2348/69 7064120 YP_002331960.1 CDS yjfM NC_011601.1 4759683 4760321 D hypothetical protein 4759683..4760321 Escherichia coli O127:H6 str. E2348/69 7064121 YP_002331961.1 CDS yjfC NC_011601.1 4760324 4761487 D synthetase/amidase 4760324..4761487 Escherichia coli O127:H6 str. E2348/69 7064122 YP_002331962.1 CDS aidB NC_011601.1 4761571 4763196 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4761571..4763196 Escherichia coli O127:H6 str. E2348/69 7064116 YP_002331963.1 CDS yjfN NC_011601.1 4763313 4763588 R hypothetical protein complement(4763313..4763588) Escherichia coli O127:H6 str. E2348/69 7062427 YP_002331964.1 CDS yjfO NC_011601.1 4763737 4764066 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(4763737..4764066) Escherichia coli O127:H6 str. E2348/69 7064123 YP_002331965.1 CDS yjfP NC_011601.1 4764248 4764997 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4764248..4764997 Escherichia coli O127:H6 str. E2348/69 7064124 YP_002331966.1 CDS ulaR NC_011601.1 4764994 4765749 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4764994..4765749) Escherichia coli O127:H6 str. E2348/69 7064125 YP_002331967.1 CDS ulaG NC_011601.1 4765857 4766921 R L-ascorbate 6-phosphate lactonase complement(4765857..4766921) Escherichia coli O127:H6 str. E2348/69 7062323 YP_002331968.1 CDS ulaA NC_011601.1 4767276 4768673 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4767276..4768673 Escherichia coli O127:H6 str. E2348/69 7062322 YP_002331969.1 CDS ulaB NC_011601.1 4768689 4768994 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4768689..4768994 Escherichia coli O127:H6 str. E2348/69 7062316 YP_002331970.1 CDS ulaC NC_011601.1 4769004 4769468 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4769004..4769468 Escherichia coli O127:H6 str. E2348/69 7062317 YP_002331971.1 CDS ulaD NC_011601.1 4769482 4770132 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4769482..4770132 Escherichia coli O127:H6 str. E2348/69 7062318 YP_002331972.1 CDS ulaE NC_011601.1 4770142 4770996 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4770142..4770996 Escherichia coli O127:H6 str. E2348/69 7062319 YP_002331973.1 CDS sgaE NC_011601.1 4770996 4771676 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4770996..4771676 Escherichia coli O127:H6 str. E2348/69 7062320 YP_002331974.1 CDS yjfY NC_011601.1 4771805 4772080 R hypothetical protein complement(4771805..4772080) Escherichia coli O127:H6 str. E2348/69 7062321 YP_002331975.1 CDS rpsF NC_011601.1 4772407 4772802 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4772407..4772802 Escherichia coli O127:H6 str. E2348/69 7064126 YP_002331976.1 CDS priB NC_011601.1 4772809 4773123 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4772809..4773123 Escherichia coli O127:H6 str. E2348/69 7061878 YP_002331977.1 CDS rpsR NC_011601.1 4773128 4773355 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4773128..4773355 Escherichia coli O127:H6 str. E2348/69 7061289 YP_002331978.1 CDS rplI NC_011601.1 4773397 4773846 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4773397..4773846 Escherichia coli O127:H6 str. E2348/69 7061890 YP_002331979.1 CDS E2348C_4527 NC_011601.1 4774248 4774727 D hypothetical protein 4774248..4774727 Escherichia coli O127:H6 str. E2348/69 7061836 YP_002331980.1 CDS E2348C_4529 NC_011601.1 4776151 4777428 R hexuronate transporter complement(4776151..4777428) Escherichia coli O127:H6 str. E2348/69 7065149 YP_002331981.1 CDS E2348C_4530 NC_011601.1 4777521 4779593 R oxidoreductase complement(4777521..4779593) Escherichia coli O127:H6 str. E2348/69 7065150 YP_002331982.1 CDS E2348C_4531 NC_011601.1 4779590 4781131 R acetyl-CoA: acetoacetyl-CoA transferase complement(4779590..4781131) Escherichia coli O127:H6 str. E2348/69 7065151 YP_002331983.1 CDS E2348C_4532 NC_011601.1 4781141 4781917 R 3-hydroxybutyryl-CoA dehydratase complement(4781141..4781917) Escherichia coli O127:H6 str. E2348/69 7065152 YP_002331984.1 CDS E2348C_4533 NC_011601.1 4781927 4782769 R hypothetical protein complement(4781927..4782769) Escherichia coli O127:H6 str. E2348/69 7065153 YP_002331985.1 CDS E2348C_4534 NC_011601.1 4782779 4783570 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(4782779..4783570) Escherichia coli O127:H6 str. E2348/69 7065154 YP_002331986.1 CDS ytfA NC_011601.1 4783784 4784431 D transcriptional regulator 4783784..4784431 Escherichia coli O127:H6 str. E2348/69 7065155 YP_002331987.1 CDS ytfB NC_011601.1 4784415 4785053 R cell envelope opacity-associated protein complement(4784415..4785053) Escherichia coli O127:H6 str. E2348/69 7063240 YP_002331988.1 CDS fklB NC_011601.1 4785271 4785891 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4785271..4785891 Escherichia coli O127:H6 str. E2348/69 7063241 YP_002331989.1 CDS cycA NC_011601.1 4787758 4789170 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4787758..4789170 Escherichia coli O127:H6 str. E2348/69 7065156 YP_002331990.1 CDS ytfE NC_011601.1 4789215 4789877 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4789215..4789877) Escherichia coli O127:H6 str. E2348/69 7065183 YP_002331991.1 CDS ytfF NC_011601.1 4789985 4790959 R hypothetical protein complement(4789985..4790959) Escherichia coli O127:H6 str. E2348/69 7063242 YP_002331992.1 CDS ytfG NC_011601.1 4791059 4791919 R NAD(P)H: quinone oxidoreductase complement(4791059..4791919) Escherichia coli O127:H6 str. E2348/69 7063243 YP_002331993.1 CDS ytfH NC_011601.1 4792008 4792388 D transcriptional regulator 4792008..4792388 Escherichia coli O127:H6 str. E2348/69 7063244 YP_002331994.1 CDS cpdB NC_011601.1 4792517 4794460 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4792517..4794460) Escherichia coli O127:H6 str. E2348/69 7063245 YP_002331995.1 CDS cysQ NC_011601.1 4794650 4795390 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4794650..4795390 Escherichia coli O127:H6 str. E2348/69 7062835 YP_002331996.1 CDS ytfJ NC_011601.1 4795380 4795937 R transcriptional regulator complement(4795380..4795937) Escherichia coli O127:H6 str. E2348/69 7065205 YP_002331997.1 CDS ytfK NC_011601.1 4796262 4796468 D hypothetical protein 4796262..4796468 Escherichia coli O127:H6 str. E2348/69 7063246 YP_002331998.1 CDS ytfL NC_011601.1 4796546 4797889 R hypothetical protein complement(4796546..4797889) Escherichia coli O127:H6 str. E2348/69 7063247 YP_002331999.1 CDS msrA NC_011601.1 4798212 4798850 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4798212..4798850) Escherichia coli O127:H6 str. E2348/69 7063248 YP_002332000.1 CDS ytfM NC_011601.1 4799056 4800789 D outer membrane protein 4799056..4800789 Escherichia coli O127:H6 str. E2348/69 7060874 YP_002332001.1 CDS ytfN NC_011601.1 4800786 4804565 D hypothetical protein 4800786..4804565 Escherichia coli O127:H6 str. E2348/69 7063249 YP_002332002.1 CDS ytfP NC_011601.1 4804568 4804909 D hypothetical protein 4804568..4804909 Escherichia coli O127:H6 str. E2348/69 7063250 YP_002332003.1 CDS ppa NC_011601.1 4805289 4805819 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4805289..4805819) Escherichia coli O127:H6 str. E2348/69 7063251 YP_002332004.1 CDS ytfQ NC_011601.1 4806129 4807085 D sugar transporter subunit: periplasmic-binding component of ABC superfamily 4806129..4807085 Escherichia coli O127:H6 str. E2348/69 7061262 YP_002332005.1 CDS ytfR NC_011601.1 4807225 4808727 D sugar transporter subunit: ATP-binding component of ABC superfamily 4807225..4808727 Escherichia coli O127:H6 str. E2348/69 7063252 YP_002332006.1 CDS ytfT NC_011601.1 4808741 4809763 D sugar transporter subunit: membrane component of ABC superfamily 4808741..4809763 Escherichia coli O127:H6 str. E2348/69 7063253 YP_002332007.1 CDS yjfF NC_011601.1 4809750 4810745 D membrane component of a sugar ABC transporter system; ABC transporter permease 4809750..4810745 Escherichia coli O127:H6 str. E2348/69 7063254 YP_002332008.1 CDS fbp NC_011601.1 4810778 4811776 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4810778..4811776) Escherichia coli O127:H6 str. E2348/69 7064117 YP_002332009.1 CDS mpl NC_011601.1 4811952 4813325 D UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 4811952..4813325 Escherichia coli O127:H6 str. E2348/69 7062083 YP_002332010.1 CDS yjgA NC_011601.1 4813477 4814028 R hypothetical protein complement(4813477..4814028) Escherichia coli O127:H6 str. E2348/69 7063825 YP_002332011.1 CDS pmbA NC_011601.1 4814122 4815474 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4814122..4815474 Escherichia coli O127:H6 str. E2348/69 7064127 YP_002332012.1 CDS cybC NC_011601.1 4815657 4816043 D cytochrome b562 4815657..4816043 Escherichia coli O127:H6 str. E2348/69 7060759 YP_002332013.1 CDS nrdG NC_011601.1 4816088 4816552 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4816088..4816552) Escherichia coli O127:H6 str. E2348/69 7065182 YP_002332014.1 CDS nrdD NC_011601.1 4816710 4818848 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4816710..4818848) Escherichia coli O127:H6 str. E2348/69 7065414 YP_002332015.1 CDS treC NC_011601.1 4819242 4820897 R trehalose-6-phosphate hydrolase complement(4819242..4820897) Escherichia coli O127:H6 str. E2348/69 7065411 YP_002332016.1 CDS treB NC_011601.1 4820947 4822368 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(4820947..4822368) Escherichia coli O127:H6 str. E2348/69 7062235 YP_002332017.1 CDS treR NC_011601.1 4822487 4823434 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4822487..4823434) Escherichia coli O127:H6 str. E2348/69 7062234 YP_002332018.1 CDS mgtA NC_011601.1 4823813 4826509 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4823813..4826509 Escherichia coli O127:H6 str. E2348/69 7062237 YP_002332019.1 CDS yjgF NC_011601.1 4826715 4827101 R ketoacid-binding protein complement(4826715..4827101) Escherichia coli O127:H6 str. E2348/69 7063782 YP_002332020.1 CDS pyrI NC_011601.1 4827174 4827635 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(4827174..4827635) Escherichia coli O127:H6 str. E2348/69 7064129 YP_002332021.1 CDS pyrB NC_011601.1 4827648 4828583 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(4827648..4828583) Escherichia coli O127:H6 str. E2348/69 7063936 YP_002332022.1 CDS pyrL NC_011601.1 4828587 4828721 R pyrBI operon leader peptide complement(4828587..4828721) Escherichia coli O127:H6 str. E2348/69 7063929 YP_002332023.1 CDS yjgH NC_011601.1 4829002 4829397 R mRNA endoribonuclease complement(4829002..4829397) Escherichia coli O127:H6 str. E2348/69 7063937 YP_002332024.1 CDS yjgI NC_011601.1 4829528 4830241 R oxidoreductase complement(4829528..4830241) Escherichia coli O127:H6 str. E2348/69 7064130 YP_002332025.1 CDS yjgJ NC_011601.1 4830312 4830905 D transcriptional regulator 4830312..4830905 Escherichia coli O127:H6 str. E2348/69 7064131 YP_002332026.1 CDS yjgK NC_011601.1 4831050 4831502 D hypothetical protein 4831050..4831502 Escherichia coli O127:H6 str. E2348/69 7064132 YP_002332027.1 CDS argI NC_011601.1 4833304 4834317 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(4833304..4834317) Escherichia coli O127:H6 str. E2348/69 7064134 YP_002332028.1 CDS rraB NC_011601.1 4834479 4834895 D hypothetical protein 4834479..4834895 Escherichia coli O127:H6 str. E2348/69 7061372 YP_002332029.1 CDS yjgM NC_011601.1 4834941 4835444 R acetyltransferase complement(4834941..4835444) Escherichia coli O127:H6 str. E2348/69 7061895 YP_002332030.1 CDS yjgN NC_011601.1 4835637 4836824 D hypothetical protein 4835637..4836824 Escherichia coli O127:H6 str. E2348/69 7064135 YP_002332031.1 CDS valS NC_011601.1 4836871 4839726 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4836871..4839726) Escherichia coli O127:H6 str. E2348/69 7064136 YP_002332032.1 CDS holC NC_011601.1 4839726 4840169 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4839726..4840169) Escherichia coli O127:H6 str. E2348/69 7062352 YP_002332033.1 CDS pepA NC_011601.1 4840331 4841842 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4840331..4841842) Escherichia coli O127:H6 str. E2348/69 7062173 YP_002332034.1 CDS yjgP NC_011601.1 4842109 4843209 D hypothetical protein 4842109..4843209 Escherichia coli O127:H6 str. E2348/69 7062945 YP_002332035.1 CDS yjgQ NC_011601.1 4843209 4844291 D hypothetical protein 4843209..4844291 Escherichia coli O127:H6 str. E2348/69 7064137 YP_002332036.1 CDS yjgR NC_011601.1 4844399 4845913 R ATPase complement(4844399..4845913) Escherichia coli O127:H6 str. E2348/69 7064138 YP_002332037.1 CDS yjgB NC_011601.1 4846043 4847062 R alcohol dehydrogenase, Zn-dependentand NAD(P)-binding complement(4846043..4847062) Escherichia coli O127:H6 str. E2348/69 7064139 YP_002332038.1 CDS E2348C_4589 NC_011601.1 4847860 4848408 D hypothetical protein 4847860..4848408 Escherichia coli O127:H6 str. E2348/69 7061165 YP_002332039.1 CDS E2348C_4590 NC_011601.1 4849160 4849921 R hypothetical protein complement(4849160..4849921) Escherichia coli O127:H6 str. E2348/69 7065157 YP_002332040.1 CDS E2348C_4591 NC_011601.1 4850315 4850884 D serine site-specific recombinase 4850315..4850884 Escherichia coli O127:H6 str. E2348/69 7065158 YP_002332041.1 CDS E2348C_4592 NC_011601.1 4850887 4851123 D hypothetical protein 4850887..4851123 Escherichia coli O127:H6 str. E2348/69 7065159 YP_002332042.1 CDS E2348C_4593 NC_011601.1 4852747 4853994 D ATP-dependent DNA helicase (N-terminus) 4852747..4853994 Escherichia coli O127:H6 str. E2348/69 7065160 YP_002332043.1 CDS E2348C_4594 NC_011601.1 4854032 4854469 D hypothetical protein 4854032..4854469 Escherichia coli O127:H6 str. E2348/69 7065161 YP_002332044.1 CDS E2348C_4595 NC_011601.1 4854466 4854675 D hypothetical protein 4854466..4854675 Escherichia coli O127:H6 str. E2348/69 7065162 YP_002332045.1 CDS E2348C_4596 NC_011601.1 4854845 4855408 D hypothetical protein 4854845..4855408 Escherichia coli O127:H6 str. E2348/69 7064923 YP_002332046.1 CDS E2348C_4597 NC_011601.1 4855405 4855641 D hypothetical protein 4855405..4855641 Escherichia coli O127:H6 str. E2348/69 7064924 YP_002332047.1 CDS E2348C_4598 NC_011601.1 4855654 4855893 D hypothetical protein 4855654..4855893 Escherichia coli O127:H6 str. E2348/69 7064925 YP_002332048.1 CDS E2348C_4599 NC_011601.1 4855897 4856577 D hypothetical protein 4855897..4856577 Escherichia coli O127:H6 str. E2348/69 7064926 YP_002332049.1 CDS E2348C_4600 NC_011601.1 4856717 4857130 D hypothetical protein 4856717..4857130 Escherichia coli O127:H6 str. E2348/69 7064927 YP_002332050.1 CDS E2348C_4601 NC_011601.1 4857350 4858345 D capsid protein 4857350..4858345 Escherichia coli O127:H6 str. E2348/69 7064928 YP_002332051.1 CDS E2348C_4602 NC_011601.1 4858362 4858871 D endonuclease, HNH family 4858362..4858871 Escherichia coli O127:H6 str. E2348/69 7064929 YP_002332052.1 CDS E2348C_4603 NC_011601.1 4858890 4859315 D hypothetical protein 4858890..4859315 Escherichia coli O127:H6 str. E2348/69 7064930 YP_002332053.1 CDS E2348C_4604 NC_011601.1 4859347 4859598 D hypothetical protein 4859347..4859598 Escherichia coli O127:H6 str. E2348/69 7064931 YP_002332054.1 CDS E2348C_4605 NC_011601.1 4859571 4859996 D hypothetical protein 4859571..4859996 Escherichia coli O127:H6 str. E2348/69 7064932 YP_002332055.1 CDS E2348C_4606 NC_011601.1 4860038 4860940 R hypothetical protein complement(4860038..4860940) Escherichia coli O127:H6 str. E2348/69 7064933 YP_002332056.1 CDS E2348C_4607 NC_011601.1 4861028 4862239 R integrase complement(4861028..4862239) Escherichia coli O127:H6 str. E2348/69 7064934 YP_002332057.1 CDS E2348C_4608 NC_011601.1 4862628 4865744 R type I restriction-modification enzyme R subunit complement(4862628..4865744) Escherichia coli O127:H6 str. E2348/69 7064935 YP_002332058.1 CDS E2348C_4609 NC_011601.1 4865866 4867092 R type I restriction-modification enzyme S subunit complement(4865866..4867092) Escherichia coli O127:H6 str. E2348/69 7064936 YP_002332059.1 CDS E2348C_4610 NC_011601.1 4867089 4868645 R type I restriction-modification enzyme M subunit complement(4867089..4868645) Escherichia coli O127:H6 str. E2348/69 7064937 YP_002332060.1 CDS E2348C_4611 NC_011601.1 4868952 4869785 D hypothetical protein 4868952..4869785 Escherichia coli O127:H6 str. E2348/69 7064938 YP_002332061.1 CDS E2348C_4612 NC_011601.1 4870147 4872201 D McrB family protein, GTPase subunit of restriction endonuclease 4870147..4872201 Escherichia coli O127:H6 str. E2348/69 7064939 YP_002332062.1 CDS E2348C_4613 NC_011601.1 4872198 4873508 D McrC family protein, McrBC 5-methylcytosine restriction system component 4872198..4873508 Escherichia coli O127:H6 str. E2348/69 7064940 YP_002332063.1 CDS E2348C_4614 NC_011601.1 4873571 4874476 R restriction endonuclease complement(4873571..4874476) Escherichia coli O127:H6 str. E2348/69 7064941 YP_002332064.1 CDS yjhS NC_011601.1 4875238 4876218 R hypothetical protein complement(4875238..4876218) Escherichia coli O127:H6 str. E2348/69 7064943 YP_002332065.1 CDS yjhT NC_011601.1 4876283 4877389 R N-acetylneuraminic acid mutarotase complement(4876283..4877389) Escherichia coli O127:H6 str. E2348/69 7064140 YP_002332066.1 CDS nanC NC_011601.1 4877409 4878125 R N-acetylnuraminic acid outer membrane channel protein complement(4877409..4878125) Escherichia coli O127:H6 str. E2348/69 7064141 YP_002332067.1 CDS fimB NC_011601.1 4879589 4880191 D inversion of on/off regulator of fimA; tyrosine recombinase 4879589..4880191 Escherichia coli O127:H6 str. E2348/69 7060919 YP_002332068.1 CDS fimE NC_011601.1 4880669 4881265 D inversion of on/off regulator of fimA; tyrosine recombinase 4880669..4881265 Escherichia coli O127:H6 str. E2348/69 7062120 YP_002332069.1 CDS fimA NC_011601.1 4881746 4882294 D major type 1 subunit fimbrin (pilin) 4881746..4882294 Escherichia coli O127:H6 str. E2348/69 7062123 YP_002332070.1 CDS fimI NC_011601.1 4882359 4882898 D type 1 pilus biosynthesis fimbrial protein 4882359..4882898 Escherichia coli O127:H6 str. E2348/69 7062119 YP_002332071.1 CDS fimC NC_011601.1 4882935 4883660 D chaperone, periplasmic 4882935..4883660 Escherichia coli O127:H6 str. E2348/69 7062127 YP_002332072.1 CDS fimD NC_011601.1 4883726 4886362 D outer membrane usher protein, type 1 fimbrial synthesis 4883726..4886362 Escherichia coli O127:H6 str. E2348/69 7062121 YP_002332073.1 CDS fimF NC_011601.1 4886372 4886902 D minor component of type 1 fimbriae 4886372..4886902 Escherichia coli O127:H6 str. E2348/69 7062122 YP_002332074.1 CDS fimG NC_011601.1 4886915 4887418 D minor component of type 1 fimbriae 4886915..4887418 Escherichia coli O127:H6 str. E2348/69 7062124 YP_002332075.1 CDS fimH NC_011601.1 4887438 4888340 D minor component of type 1 fimbriae 4887438..4888340 Escherichia coli O127:H6 str. E2348/69 7062125 YP_002332076.1 CDS uxuA NC_011601.1 4889072 4890256 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4889072..4890256 Escherichia coli O127:H6 str. E2348/69 7062126 YP_002332077.1 CDS uxuB NC_011601.1 4890337 4891797 D D-mannonate oxidoreductase, NAD-binding 4890337..4891797 Escherichia coli O127:H6 str. E2348/69 7062348 YP_002332078.1 CDS uxuR NC_011601.1 4892012 4892785 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4892012..4892785 Escherichia coli O127:H6 str. E2348/69 7062349 YP_002332079.1 CDS iraD NC_011601.1 4893199 4893582 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4893199..4893582 Escherichia coli O127:H6 str. E2348/69 7062350 YP_002332080.1 CDS yjiE NC_011601.1 4894008 4894919 R DNA-binding transcriptional regulator complement(4894008..4894919) Escherichia coli O127:H6 str. E2348/69 7061278 YP_002332081.1 CDS iadA NC_011601.1 4894984 4896156 R isoaspartyl dipeptidase complement(4894984..4896156) Escherichia coli O127:H6 str. E2348/69 7064143 YP_002332082.1 CDS yjiG NC_011601.1 4896169 4896630 R hypothetical protein complement(4896169..4896630) Escherichia coli O127:H6 str. E2348/69 7063513 YP_002332083.1 CDS yjiH NC_011601.1 4896627 4897310 R hypothetical protein complement(4896627..4897310) Escherichia coli O127:H6 str. E2348/69 7064144 YP_002332084.1 CDS kptA NC_011601.1 4897458 4898114 D in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4897458..4898114 Escherichia coli O127:H6 str. E2348/69 7064145 YP_002332085.1 CDS yjiJ NC_011601.1 4898127 4899305 R hypothetical protein complement(4898127..4899305) Escherichia coli O127:H6 str. E2348/69 7061505 YP_002332086.1 CDS yjiK NC_011601.1 4899373 4900233 R hypothetical protein complement(4899373..4900233) Escherichia coli O127:H6 str. E2348/69 7064146 YP_002332087.1 CDS E2348C_4640 NC_011601.1 4900298 4900555 R hypothetical protein complement(4900298..4900555) Escherichia coli O127:H6 str. E2348/69 7064147 YP_002332088.1 CDS yjiL NC_011601.1 4900552 4901319 R ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase complement(4900552..4901319) Escherichia coli O127:H6 str. E2348/69 7064945 YP_002332089.1 CDS yjiM NC_011601.1 4901329 4902480 R 2-hydroxyglutaryl-CoA dehydratase complement(4901329..4902480) Escherichia coli O127:H6 str. E2348/69 7064148 YP_002332090.1 CDS yjiN NC_011601.1 4902596 4903876 R hypothetical protein complement(4902596..4903876) Escherichia coli O127:H6 str. E2348/69 7064149 YP_002332091.1 CDS yjiP NC_011601.1 4904061 4904981 D hypothetical protein 4904061..4904981 Escherichia coli O127:H6 str. E2348/69 7064068 YP_002332092.1 CDS yjiW NC_011601.1 4905670 4906008 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(4905670..4906008) Escherichia coli O127:H6 str. E2348/69 7061977 YP_002332093.1 CDS E2348C_4647 NC_011601.1 4906661 4908511 R helicase complement(4906661..4908511) Escherichia coli O127:H6 str. E2348/69 7061978 YP_002332094.1 CDS yjiA NC_011601.1 4908842 4909798 R GTP-binding protein YjiA complement(4908842..4909798) Escherichia coli O127:H6 str. E2348/69 7064946 YP_002332095.1 CDS yjiX NC_011601.1 4909809 4910012 R hypothetical protein complement(4909809..4910012) Escherichia coli O127:H6 str. E2348/69 7064142 YP_002332096.1 CDS yjiY NC_011601.1 4910062 4912212 R hypothetical protein complement(4910062..4912212) Escherichia coli O127:H6 str. E2348/69 7061979 YP_002332097.1 CDS tsr NC_011601.1 4912589 4914253 D methyl-accepting chemotaxis protein I, serine sensor receptor 4912589..4914253 Escherichia coli O127:H6 str. E2348/69 7061980 YP_002332098.1 CDS E2348C_4652 NC_011601.1 4914296 4915567 R TRAP-type C4-dicarboxylate transport system, large permease component complement(4914296..4915567) Escherichia coli O127:H6 str. E2348/69 7062272 YP_002332099.1 CDS E2348C_4653 NC_011601.1 4915564 4916037 R TRAP-type C4-dicarboxylate transport system, small permease component complement(4915564..4916037) Escherichia coli O127:H6 str. E2348/69 7064947 YP_002332100.1 CDS E2348C_4655 NC_011601.1 4917762 4919414 D Na+/H+ and K+/H+ transporter 4917762..4919414 Escherichia coli O127:H6 str. E2348/69 7064949 YP_002332101.1 CDS yjjM NC_011601.1 4919585 4920490 R DNA-binding transcriptional regulator complement(4919585..4920490) Escherichia coli O127:H6 str. E2348/69 7064950 YP_002332102.1 CDS yjjN NC_011601.1 4920629 4921651 D oxidoreductase, Zn-dependent and NAD (P)-binding 4920629..4921651 Escherichia coli O127:H6 str. E2348/69 7061986 YP_002332103.1 CDS mdoB NC_011601.1 4921791 4924082 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4921791..4924082) Escherichia coli O127:H6 str. E2348/69 7061987 YP_002332104.1 CDS yjjA NC_011601.1 4924336 4924833 R hypothetical protein complement(4924336..4924833) Escherichia coli O127:H6 str. E2348/69 7065301 YP_002332105.1 CDS dnaC NC_011601.1 4924879 4925616 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4924879..4925616) Escherichia coli O127:H6 str. E2348/69 7061981 YP_002332106.1 CDS dnaT NC_011601.1 4925619 4926158 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4925619..4926158) Escherichia coli O127:H6 str. E2348/69 7065046 YP_002332107.1 CDS yjjB NC_011601.1 4926265 4926738 R hypothetical protein complement(4926265..4926738) Escherichia coli O127:H6 str. E2348/69 7065053 YP_002332108.1 CDS yjjP NC_011601.1 4926729 4927499 R hypothetical protein complement(4926729..4927499) Escherichia coli O127:H6 str. E2348/69 7061982 YP_002332109.1 CDS yjjQ NC_011601.1 4928118 4928843 D DNA-binding transcriptional regulator 4928118..4928843 Escherichia coli O127:H6 str. E2348/69 7061988 YP_002332110.1 CDS bglJ NC_011601.1 4928801 4929478 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4928801..4929478 Escherichia coli O127:H6 str. E2348/69 7061989 YP_002332111.1 CDS fhuF NC_011601.1 4929516 4930304 R ferric hydroximate transport ferric iron reductase complement(4929516..4930304) Escherichia coli O127:H6 str. E2348/69 7062517 YP_002332112.1 CDS yjjZ NC_011601.1 4930445 4930681 D hypothetical protein 4930445..4930681 Escherichia coli O127:H6 str. E2348/69 7062116 YP_002332113.1 CDS rsmC NC_011601.1 4931343 4932374 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4931343..4932374) Escherichia coli O127:H6 str. E2348/69 7061529 YP_002332114.1 CDS holD NC_011601.1 4932477 4932890 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4932477..4932890 Escherichia coli O127:H6 str. E2348/69 7064556 YP_002332115.1 CDS rimI NC_011601.1 4932859 4933305 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4932859..4933305 Escherichia coli O127:H6 str. E2348/69 7062174 YP_002332116.1 CDS yjjG NC_011601.1 4933320 4933997 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4933320..4933997 Escherichia coli O127:H6 str. E2348/69 7060827 YP_002332117.1 CDS prfC NC_011601.1 4934088 4935677 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4934088..4935677 Escherichia coli O127:H6 str. E2348/69 7061983 YP_002332118.1 CDS osmY NC_011601.1 4936070 4936675 D hypothetical protein 4936070..4936675 Escherichia coli O127:H6 str. E2348/69 7061286 YP_002332119.1 CDS ytjA NC_011601.1 4936802 4936963 D hypothetical protein 4936802..4936963 Escherichia coli O127:H6 str. E2348/69 7062893 YP_002332120.1 CDS yjjU NC_011601.1 4937085 4938158 D esterase 4937085..4938158 Escherichia coli O127:H6 str. E2348/69 7063255 YP_002332121.1 CDS yjjV NC_011601.1 4938155 4938934 D deoxyribonuclease YjjV 4938155..4938934 Escherichia coli O127:H6 str. E2348/69 7061990 YP_002332122.1 CDS yjjW NC_011601.1 4939151 4940014 R pyruvate formate lyase activating enzyme complement(4939151..4940014) Escherichia coli O127:H6 str. E2348/69 7061991 YP_002332123.1 CDS yjjI NC_011601.1 4939986 4941536 R hypothetical protein complement(4939986..4941536) Escherichia coli O127:H6 str. E2348/69 7061992 YP_002332124.1 CDS deoC NC_011601.1 4941794 4942573 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4941794..4942573 Escherichia coli O127:H6 str. E2348/69 7061984 YP_002332125.1 CDS deoA NC_011601.1 4942651 4943973 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4942651..4943973 Escherichia coli O127:H6 str. E2348/69 7065009 YP_002332126.1 CDS deoB NC_011601.1 4944025 4945248 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4944025..4945248 Escherichia coli O127:H6 str. E2348/69 7065007 YP_002332127.1 CDS deoD NC_011601.1 4945305 4946024 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4945305..4946024 Escherichia coli O127:H6 str. E2348/69 7065008 YP_002332128.1 CDS E2348C_4683 NC_011601.1 4946185 4946448 R hypothetical protein complement(4946185..4946448) Escherichia coli O127:H6 str. E2348/69 7065010 YP_002332129.1 CDS lplA NC_011601.1 4946480 4947496 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(4946480..4947496) Escherichia coli O127:H6 str. E2348/69 7064951 YP_002332130.1 CDS ytjB NC_011601.1 4947524 4948168 R hypothetical protein complement(4947524..4948168) Escherichia coli O127:H6 str. E2348/69 7061567 YP_002332131.1 CDS serB NC_011601.1 4948274 4949242 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4948274..4949242 Escherichia coli O127:H6 str. E2348/69 7063256 YP_002332132.1 CDS radA NC_011601.1 4949291 4950673 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4949291..4950673 Escherichia coli O127:H6 str. E2348/69 7065367 YP_002332133.1 CDS nadR NC_011601.1 4950694 4951926 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4950694..4951926 Escherichia coli O127:H6 str. E2348/69 7063946 YP_002332134.1 CDS E2348C_4689 NC_011601.1 4952018 4952350 D hypothetical protein 4952018..4952350 Escherichia coli O127:H6 str. E2348/69 7060910 YP_002332135.1 CDS E2348C_4690 NC_011601.1 4952352 4952636 D regulatory protein 4952352..4952636 Escherichia coli O127:H6 str. E2348/69 7064952 YP_002332136.1 CDS yjjK NC_011601.1 4952692 4954359 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(4952692..4954359) Escherichia coli O127:H6 str. E2348/69 7064953 YP_002332137.1 CDS slt NC_011601.1 4954695 4956632 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4954695..4956632 Escherichia coli O127:H6 str. E2348/69 7061985 YP_002332138.1 CDS trpR NC_011601.1 4956722 4957048 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4956722..4957048 Escherichia coli O127:H6 str. E2348/69 7062722 YP_002332139.1 CDS yjjX NC_011601.1 4957121 4957648 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(4957121..4957648) Escherichia coli O127:H6 str. E2348/69 7062260 YP_002332140.1 CDS rob NC_011601.1 4958344 4959213 R DNA-binding transcriptional activator Rob complement(4958344..4959213) Escherichia coli O127:H6 str. E2348/69 7063257 YP_002332141.1 CDS creA NC_011601.1 4959424 4959897 D hypothetical protein 4959424..4959897 Escherichia coli O127:H6 str. E2348/69 7061822 YP_002332142.1 CDS creB NC_011601.1 4959910 4960599 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4959910..4960599 Escherichia coli O127:H6 str. E2348/69 7062842 YP_002332143.1 CDS creC NC_011601.1 4960599 4962023 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4960599..4962023 Escherichia coli O127:H6 str. E2348/69 7062843 YP_002332144.1 CDS arcA NC_011601.1 4963491 4964207 R two-component response regulator complement(4963491..4964207) Escherichia coli O127:H6 str. E2348/69 7062845 YP_002332145.1 CDS yjjY NC_011601.1 4964303 4964443 D hypothetical protein 4964303..4964443 Escherichia coli O127:H6 str. E2348/69 7061363 YP_002332146.1 CDS yjtD NC_011601.1 4964843 4965529 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 4964843..4965529 Escherichia coli O127:H6 str. E2348/69 7061994 YP_002332147.1 CDS sulII NC_011602.1 141 956 D dihydropteroate synthase 141..956 Escherichia coli O127:H6 str. E2348/69 7056255 YP_002332148.1 CDS strA NC_011602.1 1017 1820 D streptomycin phosphotransferase StrA 1017..1820 Escherichia coli O127:H6 str. E2348/69 7056264 YP_002332149.1 CDS strB NC_011602.1 1820 2656 D streptomycin phosphotransferase StrB 1820..2656 Escherichia coli O127:H6 str. E2348/69 7056262 YP_002332150.1 CDS E2348_P2_04 NC_011602.1 2628 3167 R pseudogene, N-ter part of putative transposase; hypothetical protein complement(2628..3167) Escherichia coli O127:H6 str. E2348/69 7056263 YP_002332151.1 CDS E2348_P2_05 NC_011602.1 3211 3600 R hypothetical protein complement(3211..3600) Escherichia coli O127:H6 str. E2348/69 7056256 YP_002332152.1 CDS E2348_P2_06 NC_011602.1 3770 4258 D entry exclusion protein 1 3770..4258 Escherichia coli O127:H6 str. E2348/69 7056257 YP_002332153.1 CDS E2348_P2_07 NC_011602.1 4317 4592 R hypothetical protein complement(4317..4592) Escherichia coli O127:H6 str. E2348/69 7056258 YP_002332154.1 CDS E2348_P2_08 NC_011602.1 4950 5099 R hypothetical protein complement(4950..5099) Escherichia coli O127:H6 str. E2348/69 7056259 YP_002332155.1 CDS E2348_P2_09 NC_011602.1 5224 5628 D probable plasmid replication initiation protein 5224..5628 Escherichia coli O127:H6 str. E2348/69 7056260 YP_002332156.1 CDS repI NC_011603.1 275 1252 D bind to repeated iterons in RepFIB; replication initiation protein 275..1252 Escherichia coli O127:H6 str. E2348/69 7056380 YP_002332157.1 CDS bfpA NC_011603.1 2646 3227 D major pilin structural unit bundlin 2646..3227 Escherichia coli O127:H6 str. E2348/69 7056343 YP_002332158.1 CDS bfpG NC_011603.1 3274 3675 D lipoprotein 3274..3675 Escherichia coli O127:H6 str. E2348/69 7056319 YP_002332159.1 CDS bfpB NC_011603.1 3682 5340 D lipoprotein 3682..5340 Escherichia coli O127:H6 str. E2348/69 7056325 YP_002332160.1 CDS bfpC NC_011603.1 5337 6545 D hypothetical protein 5337..6545 Escherichia coli O127:H6 str. E2348/69 7056320 YP_002332161.1 CDS bfpU NC_011603.1 6523 7017 D periplasmic protein 6523..7017 Escherichia coli O127:H6 str. E2348/69 7056321 YP_002332162.1 CDS bfpD NC_011603.1 7024 8631 D nucleotide binding protein 7024..8631 Escherichia coli O127:H6 str. E2348/69 7056331 YP_002332163.1 CDS bfpE NC_011603.1 8638 9696 D transmembrane protein 8638..9696 Escherichia coli O127:H6 str. E2348/69 7056322 YP_002332164.1 CDS bfpF NC_011603.1 9680 10675 D nucleotide binding protein 9680..10675 Escherichia coli O127:H6 str. E2348/69 7056323 YP_002332165.1 CDS bfpP NC_011603.1 10682 11431 D prepilin peptidase 10682..11431 Escherichia coli O127:H6 str. E2348/69 7056324 YP_002332166.1 CDS bfpH NC_011603.1 11413 11859 D lipoprotein 11413..11859 Escherichia coli O127:H6 str. E2348/69 7056330 YP_002332167.1 CDS bfpI NC_011603.1 11880 12425 D prepilin 11880..12425 Escherichia coli O127:H6 str. E2348/69 7056326 YP_002332168.1 CDS bfpJ NC_011603.1 12422 12973 D prepilin 12422..12973 Escherichia coli O127:H6 str. E2348/69 7056327 YP_002332169.1 CDS bfpK NC_011603.1 12963 13451 D prepilin 12963..13451 Escherichia coli O127:H6 str. E2348/69 7056328 YP_002332170.1 CDS bfpL NC_011603.1 13454 13903 D inner membrane protein 13454..13903 Escherichia coli O127:H6 str. E2348/69 7056329 YP_002332171.1 CDS E2348_P1_018 NC_011603.1 15490 16356 R transposase Orf2 of ISEc17 complement(15490..16356) Escherichia coli O127:H6 str. E2348/69 7056300 YP_002332172.1 CDS E2348_P1_019 NC_011603.1 16353 16652 R transposase Orf1 of ISEc17 complement(16353..16652) Escherichia coli O127:H6 str. E2348/69 7056267 YP_002332173.1 CDS perA NC_011603.1 17176 18000 D transcriptional activator of the bfp operon 17176..18000 Escherichia coli O127:H6 str. E2348/69 7056301 YP_002332174.1 CDS perB NC_011603.1 18048 18437 D transcriptional regulator 18048..18437 Escherichia coli O127:H6 str. E2348/69 7056339 YP_002332175.1 CDS perC NC_011603.1 18487 18756 D transcriptional regulator 18487..18756 Escherichia coli O127:H6 str. E2348/69 7056340 YP_002332176.1 CDS E2348_P1_033 NC_011603.1 29608 29895 R hypothetical protein complement(29608..29895) Escherichia coli O127:H6 str. E2348/69 7056272 YP_002332177.1 CDS E2348_P1_034 NC_011603.1 29892 30143 R hypothetical protein complement(29892..30143) Escherichia coli O127:H6 str. E2348/69 7056273 YP_002332178.1 CDS repA NC_011603.1 31108 31965 R RepA; replication protein complement(31108..31965) Escherichia coli O127:H6 str. E2348/69 7056274 YP_002332179.1 CDS copB NC_011603.1 32279 32527 R replication protein complement(32279..32527) Escherichia coli O127:H6 str. E2348/69 7056297 YP_002332180.1 CDS srnB NC_011603.1 32811 32960 R post-segregational killing toxin complement(32811..32960) Escherichia coli O127:H6 str. E2348/69 7056334 YP_002332181.1 CDS E2348_P1_038 NC_011603.1 33149 34522 D transposase of ISEc13 33149..34522 Escherichia coli O127:H6 str. E2348/69 7056308 YP_002332182.1 CDS finO NC_011603.1 34555 35112 R conjugal transfer fertility inhibition protein FinO complement(34555..35112) Escherichia coli O127:H6 str. E2348/69 7056275 YP_002332183.1 CDS E2348_P1_040 NC_011603.1 35215 36075 R hypothetical protein complement(35215..36075) Escherichia coli O127:H6 str. E2348/69 7056335 YP_002332184.1 CDS traX NC_011603.1 36134 36880 R conjugal transfer pilus acetylation protein TraX complement(36134..36880) Escherichia coli O127:H6 str. E2348/69 7056276 YP_002332185.1 CDS traI NC_011603.1 36900 42170 R cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer nickase/helicase TraI complement(36900..42170) Escherichia coli O127:H6 str. E2348/69 7056369 YP_002332186.1 CDS mvpT NC_011603.1 42252 42479 D post-segregational killing toxin 42252..42479 Escherichia coli O127:H6 str. E2348/69 7056355 YP_002332187.1 CDS mvpA NC_011603.1 42479 42877 D stability determinant protein; plasmid maintenance protein 42479..42877 Escherichia coli O127:H6 str. E2348/69 7056338 YP_002332188.1 CDS traD NC_011603.1 42886 45039 R type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD complement(42886..45039) Escherichia coli O127:H6 str. E2348/69 7056337 YP_002332189.1 CDS traT NC_011603.1 45292 46023 R conjugal transfer surface exclusion protein TraT complement(45292..46023) Escherichia coli O127:H6 str. E2348/69 7056350 YP_002332190.1 CDS traS NC_011603.1 46037 46546 R conjugal transfer entry exclusion protein TraS complement(46037..46546) Escherichia coli O127:H6 str. E2348/69 7056365 YP_002332191.1 CDS traG NC_011603.1 46543 49368 R conjugal transfer mating pair stabilization protein TraG complement(46543..49368) Escherichia coli O127:H6 str. E2348/69 7056364 YP_002332192.1 CDS traH NC_011603.1 49365 50738 R conjugal transfer pilus assembly protein TraH complement(49365..50738) Escherichia coli O127:H6 str. E2348/69 7056353 YP_002332193.1 CDS trbF NC_011603.1 50738 51118 R conjugal transfer protein TrbF complement(50738..51118) Escherichia coli O127:H6 str. E2348/69 7056354 YP_002332194.1 CDS trbJ NC_011603.1 51105 51446 R conjugal transfer protein TrbJ complement(51105..51446) Escherichia coli O127:H6 str. E2348/69 7056376 YP_002332195.1 CDS trbB NC_011603.1 51376 51921 R conjugal transfer protein TrbB complement(51376..51921) Escherichia coli O127:H6 str. E2348/69 7056379 YP_002332196.1 CDS traQ NC_011603.1 51908 52192 R conjugal transfer pilin chaperone TraQ complement(51908..52192) Escherichia coli O127:H6 str. E2348/69 7056372 YP_002332197.1 CDS artA NC_011603.1 52273 52587 D hypothetical protein 52273..52587 Escherichia coli O127:H6 str. E2348/69 7056362 YP_002332198.1 CDS trbA NC_011603.1 52589 52921 R conjugal transfer protein TrbA complement(52589..52921) Escherichia coli O127:H6 str. E2348/69 7056318 YP_002332199.1 CDS traF NC_011603.1 52952 53713 R type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal pilus assembly protein TraF complement(52952..53713) Escherichia coli O127:H6 str. E2348/69 7056371 YP_002332200.1 CDS trbE NC_011603.1 53688 53948 R conjugal transfer protein TrbE complement(53688..53948) Escherichia coli O127:H6 str. E2348/69 7056352 YP_002332201.1 CDS traN NC_011603.1 53973 55781 R TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN complement(53973..55781) Escherichia coli O127:H6 str. E2348/69 7056375 YP_002332202.1 CDS trbC NC_011603.1 55778 56416 R conjugal transfer pilus assembly protein TrbC complement(55778..56416) Escherichia coli O127:H6 str. E2348/69 7056360 YP_002332203.1 CDS traU NC_011603.1 56425 57417 R conjugal transfer pilus assembly protein TraU complement(56425..57417) Escherichia coli O127:H6 str. E2348/69 7056373 YP_002332204.1 CDS traW NC_011603.1 57414 58046 R conjugal transfer pilus assembly protein TraW complement(57414..58046) Escherichia coli O127:H6 str. E2348/69 7056366 YP_002332205.1 CDS trbI NC_011603.1 58043 58429 R conjugal transfer protein TrbI complement(58043..58429) Escherichia coli O127:H6 str. E2348/69 7056368 YP_002332206.1 CDS traC NC_011603.1 58426 61053 R similar to VirB4; conjugal transfer ATP-binding protein TraC complement(58426..61053) Escherichia coli O127:H6 str. E2348/69 7056378 YP_002332207.1 CDS traR NC_011603.1 61213 61434 R conjugal transfer protein TraR complement(61213..61434) Escherichia coli O127:H6 str. E2348/69 7056349 YP_002332208.1 CDS traV NC_011603.1 61569 62084 R conjugal transfer protein TraV complement(61569..62084) Escherichia coli O127:H6 str. E2348/69 7056363 YP_002332209.1 CDS trbG NC_011603.1 62081 62332 R conjugal transfer protein TrbG complement(62081..62332) Escherichia coli O127:H6 str. E2348/69 7056367 YP_002332210.1 CDS trbD NC_011603.1 62325 62645 R similar to traD of F plasmid, 96% identity in 61 aa overlap but with C-terminal extension; conjugal transfer protein TrbD complement(62325..62645) Escherichia coli O127:H6 str. E2348/69 7056377 YP_002332211.1 CDS traP NC_011603.1 62632 63222 R conjugal transfer protein TraP complement(62632..63222) Escherichia coli O127:H6 str. E2348/69 7056374 YP_002332212.1 CDS traB NC_011603.1 63212 64639 R conjugal transfer pilus assembly protein TraB complement(63212..64639) Escherichia coli O127:H6 str. E2348/69 7056361 YP_002332213.1 CDS traK NC_011603.1 64639 65367 R conjugal transfer protein TraK complement(64639..65367) Escherichia coli O127:H6 str. E2348/69 7056348 YP_002332214.1 CDS traE NC_011603.1 65354 65920 R conjugal transfer pilus assembly protein TraE complement(65354..65920) Escherichia coli O127:H6 str. E2348/69 7056357 YP_002332215.1 CDS traL NC_011603.1 65942 66253 R conjugal transfer pilus assembly protein TraL complement(65942..66253) Escherichia coli O127:H6 str. E2348/69 7056351 YP_002332216.1 CDS traA NC_011603.1 66268 66633 R conjugal transfer pilin subunit TraA complement(66268..66633) Escherichia coli O127:H6 str. E2348/69 7056358 YP_002332217.1 CDS traY NC_011603.1 66667 66894 R conjugal transfer protein TraY complement(66667..66894) Escherichia coli O127:H6 str. E2348/69 7056347 YP_002332218.1 CDS traJ NC_011603.1 66989 67675 R transcriptional activator complement(66989..67675) Escherichia coli O127:H6 str. E2348/69 7056370 YP_002332219.1 CDS traM NC_011603.1 67865 68248 R conjugal transfer protein TraM complement(67865..68248) Escherichia coli O127:H6 str. E2348/69 7056298 YP_002332220.1 CDS E2348_P1_077 NC_011603.1 68674 69183 D similar to ygfA of F plasmid, 99% identity in 169 aa overlap; lytic transglycosylase 68674..69183 Escherichia coli O127:H6 str. E2348/69 7056359 YP_002332221.1 CDS E2348_P1_078 NC_011603.1 69479 70300 R similar to ygeB of F plasmid, 98% identity in 273 aa overlap; hypothetical protein complement(69479..70300) Escherichia coli O127:H6 str. E2348/69 7056277 YP_002332222.1 CDS E2348_P1_081 NC_011603.1 71571 72944 R transposase of ISEc13 complement(71571..72944) Escherichia coli O127:H6 str. E2348/69 7056309 YP_002332223.1 CDS E2348_P1_083 NC_011603.1 73574 74935 R hypothetical protein complement(73574..74935) Escherichia coli O127:H6 str. E2348/69 7056281 YP_002332224.1 CDS E2348_P1_084 NC_011603.1 74939 75199 D hypothetical protein 74939..75199 Escherichia coli O127:H6 str. E2348/69 7056282 YP_002332225.1 CDS E2348_P1_085 NC_011603.1 75635 76057 D conserved predicted protein 75635..76057 Escherichia coli O127:H6 str. E2348/69 7056283 YP_002332226.1 CDS E2348_P1_086 NC_011603.1 76395 76814 R hypothetical protein complement(76395..76814) Escherichia coli O127:H6 str. E2348/69 7056284 YP_002332227.1 CDS E2348_P1_087 NC_011603.1 76861 77286 R hypothetical protein complement(76861..77286) Escherichia coli O127:H6 str. E2348/69 7056285 YP_002332228.1 CDS E2348_P1_090 NC_011603.1 78922 80073 R transposase of IS30 complement(78922..80073) Escherichia coli O127:H6 str. E2348/69 7056311 YP_002332229.1 CDS E2348_P1_092 NC_011603.1 81016 82092 D transposase of ISEc13 of IS110 family 81016..82092 Escherichia coli O127:H6 str. E2348/69 7056313 YP_002332230.1 CDS E2348_P1_096 NC_011603.1 83582 85042 D putative glutamate:gamma-aminobutyrate antiporter 83582..85042 Escherichia coli O127:H6 str. E2348/69 7056288 YP_002332231.1 CDS E2348_P1_097 NC_011603.1 85076 85885 D putative glutamate racemase 85076..85885 Escherichia coli O127:H6 str. E2348/69 7056289 YP_002332232.1 CDS E2348_P1_098 NC_011603.1 86004 86399 R transposase Orf1 of IS1N complement(86004..86399) Escherichia coli O127:H6 str. E2348/69 7056316 YP_002332233.1 CDS E2348_P1_099 NC_011603.1 86426 86698 R transposase Orf2 of IS1N complement(86426..86698) Escherichia coli O127:H6 str. E2348/69 7056290 YP_002332234.1 CDS stbB NC_011603.1 88216 88608 R plasmid stability protein complement(88216..88608) Escherichia coli O127:H6 str. E2348/69 7056336 YP_002332235.1 CDS stbA NC_011603.1 88613 89584 R plasmid stability protein complement(88613..89584) Escherichia coli O127:H6 str. E2348/69 7056346 YP_002332236.1 CDS E2348_P1_103 NC_011603.1 89813 90457 D ParA-like protein, putative partitioning protein 89813..90457 Escherichia coli O127:H6 str. E2348/69 7056345 YP_002332237.1 CDS E2348_P1_104 NC_011603.1 90451 90726 D hypothetical protein 90451..90726 Escherichia coli O127:H6 str. E2348/69 7056292 YP_002332238.1 CDS rsvB NC_011603.1 90864 91673 R putative resolvase complement(90864..91673) Escherichia coli O127:H6 str. E2348/69 7056293 YP_002332239.1 CDS ccdB NC_011603.1 91674 91979 R controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB complement(91674..91979) Escherichia coli O127:H6 str. E2348/69 7056344 YP_002332240.1 CDS ccdA NC_011603.1 91981 92199 R plasmid maintenance protein CcdA complement(91981..92199) Escherichia coli O127:H6 str. E2348/69 7056333 YP_002332241.1 CDS E2348_P1_108 NC_011603.1 92913 95534 D hypothetical protein 92913..95534 Escherichia coli O127:H6 str. E2348/69 7056332 YP_002332242.1 CDS E2348_P1_109 NC_011603.1 95733 95963 D VagC-like protein, putative plasmid maintenance protein 95733..95963 Escherichia coli O127:H6 str. E2348/69 7056294 YP_002332243.1 CDS E2348_P1_110 NC_011603.1 95960 96310 D VagD-like protein, putative plasmid maintenance protein 95960..96310 Escherichia coli O127:H6 str. E2348/69 7056295 YP_002332244.1 CDS E2348_P1_111 NC_011603.1 96550 97080 R hypothetical protein complement(96550..97080) Escherichia coli O127:H6 str. E2348/69 7056317 YP_002332245.1 CDS E2348_P1_112 NC_011603.1 97084 97353 R hypothetical protein complement(97084..97353) Escherichia coli O127:H6 str. E2348/69 7056296 E2348C_tRNA01 tRNA ileV NC_011601.1 235336 235412 D tRNA-Ile 235336..235412 Escherichia coli O127:H6 str. E2348/69 7064548 E2348C_tRNA02 tRNA alaV NC_011601.1 235455 235530 D tRNA-Ala 235455..235530 Escherichia coli O127:H6 str. E2348/69 7063526 E2348C_tRNA03 tRNA aspU NC_011601.1 238888 238964 D tRNA-Asp 238888..238964 Escherichia coli O127:H6 str. E2348/69 7064532 E2348C_tRNA04 tRNA aspV NC_011601.1 247112 247188 D tRNA-Asp 247112..247188 Escherichia coli O127:H6 str. E2348/69 7065052 E2348C_tRNA05 tRNA thrW NC_011601.1 269401 269476 D tRNA-Thr 269401..269476 Escherichia coli O127:H6 str. E2348/69 7061296 E2348C_tRNA06 tRNA argU NC_011601.1 515914 515990 D tRNA-Arg 515914..515990 Escherichia coli O127:H6 str. E2348/69 7061941 E2348C_tRNA07 tRNA glnV NC_011601.1 618156 618230 R tRNA-Gln complement(618156..618230) Escherichia coli O127:H6 str. E2348/69 7062295 E2348C_tRNA08 tRNA metU NC_011601.1 618279 618355 R tRNA-Met complement(618279..618355) Escherichia coli O127:H6 str. E2348/69 7061688 E2348C_tRNA09 tRNA glnW NC_011601.1 618371 618445 R tRNA-Gln complement(618371..618445) Escherichia coli O127:H6 str. E2348/69 7063771 E2348C_tRNA10 tRNA glnU NC_011601.1 618480 618554 R tRNA-Gln complement(618480..618554) Escherichia coli O127:H6 str. E2348/69 7061689 E2348C_tRNA11 tRNA leuW NC_011601.1 618578 618662 R tRNA-Leu complement(618578..618662) Escherichia coli O127:H6 str. E2348/69 7061687 E2348C_tRNA12 tRNA metT NC_011601.1 618673 618749 R tRNA-Met complement(618673..618749) Escherichia coli O127:H6 str. E2348/69 7061534 E2348C_tRNA13 tRNA lysT NC_011601.1 694423 694498 D tRNA-Lys 694423..694498 Escherichia coli O127:H6 str. E2348/69 7063269 E2348C_tRNA14 tRNA valT NC_011601.1 694534 694609 D tRNA-Val 694534..694609 Escherichia coli O127:H6 str. E2348/69 7065257 E2348C_tRNA15 tRNA lysW NC_011601.1 694612 694687 D tRNA-Lys 694612..694687 Escherichia coli O127:H6 str. E2348/69 7062353 E2348C_tRNA16 tRNA valZ NC_011601.1 694739 694814 D tRNA-Val 694739..694814 Escherichia coli O127:H6 str. E2348/69 7065260 E2348C_tRNA17 tRNA lysY NC_011601.1 694818 694893 D tRNA-Lys 694818..694893 Escherichia coli O127:H6 str. E2348/69 7062359 E2348C_tRNA18 tRNA lysZ NC_011601.1 694942 695017 D tRNA-Lys 694942..695017 Escherichia coli O127:H6 str. E2348/69 7065261 E2348C_tRNA19 tRNA lysQ_1 NC_011601.1 695051 695126 D tRNA-Lys 695051..695126 Escherichia coli O127:H6 str. E2348/69 7065262 E2348C_tRNA20 tRNA lysQ_2 NC_011601.1 695160 695235 D tRNA-Lys 695160..695235 Escherichia coli O127:H6 str. E2348/69 7065253 E2348C_tRNA21 tRNA serW NC_011601.1 924280 924367 R tRNA-Ser complement(924280..924367) Escherichia coli O127:H6 str. E2348/69 7062808 E2348C_tRNA22 tRNA serT NC_011601.1 1019640 1019727 R tRNA-Ser complement(1019640..1019727) Escherichia coli O127:H6 str. E2348/69 7061425 E2348C_tRNA23 tRNA serX NC_011601.1 1181078 1181165 R tRNA-Ser complement(1181078..1181165) Escherichia coli O127:H6 str. E2348/69 7064723 E2348C_tRNA24 tRNA tRNA_24 NC_011601.1 1287238 1287313 D tRNA-Ile 1287238..1287313 Escherichia coli O127:H6 str. E2348/69 7064754 E2348C_tRNA25 tRNA tRNA_25 NC_011601.1 1287321 1287397 D tRNA-OTHER 1287321..1287397 Escherichia coli O127:H6 str. E2348/69 7062246 E2348C_tRNA26 tRNA tRNA_26 NC_011601.1 1287411 1287487 D tRNA-Arg 1287411..1287487 Escherichia coli O127:H6 str. E2348/69 7062247 E2348C_tRNA27 tRNA tyrT NC_011601.1 1401370 1401454 R tRNA-Tyr complement(1401370..1401454) Escherichia coli O127:H6 str. E2348/69 7064170 E2348C_tRNA28 tRNA tRNA_28 NC_011601.1 1442730 1442805 D tRNA-Ile 1442730..1442805 Escherichia coli O127:H6 str. E2348/69 7064195 E2348C_tRNA29 tRNA tRNA_29 NC_011601.1 1442807 1442882 D tRNA-OTHER 1442807..1442882 Escherichia coli O127:H6 str. E2348/69 7062249 E2348C_tRNA30 tRNA tRNA_30 NC_011601.1 1442896 1442972 D tRNA-Arg 1442896..1442972 Escherichia coli O127:H6 str. E2348/69 7062250 E2348C_tRNA31 tRNA valV NC_011601.1 1817855 1817931 D tRNA-Val 1817855..1817931 Escherichia coli O127:H6 str. E2348/69 7063995 E2348C_tRNA32 tRNA valW NC_011601.1 1817936 1818012 D tRNA-Val 1817936..1818012 Escherichia coli O127:H6 str. E2348/69 7062355 E2348C_tRNA33 tRNA leuZ NC_011601.1 2089326 2089412 R tRNA-Leu complement(2089326..2089412) Escherichia coli O127:H6 str. E2348/69 7063033 E2348C_tRNA34 tRNA cysT NC_011601.1 2089425 2089498 R tRNA-Cys complement(2089425..2089498) Escherichia coli O127:H6 str. E2348/69 7061536 E2348C_tRNA35 tRNA glyW NC_011601.1 2089552 2089627 R tRNA-Gly complement(2089552..2089627) Escherichia coli O127:H6 str. E2348/69 7065207 E2348C_tRNA36 tRNA serU NC_011601.1 2139005 2139094 R tRNA-Ser complement(2139005..2139094) Escherichia coli O127:H6 str. E2348/69 7061217 E2348C_tRNA37 tRNA asnT NC_011601.1 2140086 2140161 D tRNA-Asn 2140086..2140161 Escherichia coli O127:H6 str. E2348/69 7060877 E2348C_tRNA38 tRNA asnW NC_011601.1 2173062 2173137 R tRNA-Asn complement(2173062..2173137) Escherichia coli O127:H6 str. E2348/69 7060967 E2348C_tRNA39 tRNA asnU NC_011601.1 2174886 2174961 D tRNA-Asn 2174886..2174961 Escherichia coli O127:H6 str. E2348/69 7063065 E2348C_tRNA40 tRNA asnV NC_011601.1 2177295 2177370 D tRNA-Asn 2177295..2177370 Escherichia coli O127:H6 str. E2348/69 7060903 E2348C_tRNA41 tRNA proL NC_011601.1 2416995 2417071 D tRNA-Pro 2416995..2417071 Escherichia coli O127:H6 str. E2348/69 7063128 E2348C_tRNA42 tRNA argW NC_011601.1 2586442 2586516 D tRNA-Arg 2586442..2586516 Escherichia coli O127:H6 str. E2348/69 7063176 E2348C_tRNA43 tRNA tRNA_43 NC_011601.1 2611987 2612062 R tRNA-Thr complement(2611987..2612062) Escherichia coli O127:H6 str. E2348/69 7061010 E2348C_tRNA44 tRNA tRNA_44 NC_011601.1 2612068 2612142 R tRNA-OTHER complement(2612068..2612142) Escherichia coli O127:H6 str. E2348/69 7062251 E2348C_tRNA45 tRNA alaX NC_011601.1 2673099 2673174 R tRNA-Ala complement(2673099..2673174) Escherichia coli O127:H6 str. E2348/69 7063182 E2348C_tRNA46 tRNA alaW NC_011601.1 2673214 2673289 R tRNA-Ala complement(2673214..2673289) Escherichia coli O127:H6 str. E2348/69 7062434 E2348C_tRNA47 tRNA valU NC_011601.1 2675988 2676063 D tRNA-Val 2675988..2676063 Escherichia coli O127:H6 str. E2348/69 7061717 E2348C_tRNA48 tRNA valX NC_011601.1 2676108 2676183 D tRNA-Val 2676108..2676183 Escherichia coli O127:H6 str. E2348/69 7062354 E2348C_tRNA49 tRNA valY NC_011601.1 2676230 2676305 D tRNA-Val 2676230..2676305 Escherichia coli O127:H6 str. E2348/69 7062357 E2348C_tRNA50 tRNA lysV NC_011601.1 2676310 2676385 D tRNA-Lys 2676310..2676385 Escherichia coli O127:H6 str. E2348/69 7062358 E2348C_tRNA51 tRNA gltW NC_011601.1 2960370 2960445 R tRNA-Glu complement(2960370..2960445) Escherichia coli O127:H6 str. E2348/69 7064538 E2348C_tRNA52 tRNA argQ NC_011601.1 3049978 3050054 R tRNA-Arg complement(3049978..3050054) Escherichia coli O127:H6 str. E2348/69 7061254 E2348C_tRNA53 tRNA argZ NC_011601.1 3050118 3050194 R tRNA-Arg complement(3050118..3050194) Escherichia coli O127:H6 str. E2348/69 7061375 E2348C_tRNA54 tRNA argY NC_011601.1 3050258 3050334 R tRNA-Arg complement(3050258..3050334) Escherichia coli O127:H6 str. E2348/69 7061384 E2348C_tRNA55 tRNA argV NC_011601.1 3050398 3050474 R tRNA-Arg complement(3050398..3050474) Escherichia coli O127:H6 str. E2348/69 7061383 E2348C_tRNA56 tRNA serV NC_011601.1 3050478 3050570 R tRNA-Ser complement(3050478..3050570) Escherichia coli O127:H6 str. E2348/69 7061380 E2348C_tRNA57 tRNA metZ NC_011601.1 3179174 3179250 D tRNA-Met 3179174..3179250 Escherichia coli O127:H6 str. E2348/69 7063794 E2348C_tRNA58 tRNA metW NC_011601.1 3179284 3179360 D tRNA-Met 3179284..3179360 Escherichia coli O127:H6 str. E2348/69 7063775 E2348C_tRNA59 tRNA metV NC_011601.1 3179394 3179470 D tRNA-Met 3179394..3179470 Escherichia coli O127:H6 str. E2348/69 7063773 E2348C_tRNA60 tRNA glyU NC_011601.1 3226254 3226327 R tRNA-Gly complement(3226254..3226327) Escherichia coli O127:H6 str. E2348/69 7063186 E2348C_tRNA61 tRNA pheV NC_011601.1 3338615 3338690 D tRNA-Phe 3338615..3338690 Escherichia coli O127:H6 str. E2348/69 7063189 E2348C_tRNA62 tRNA ileX NC_011601.1 3500243 3500318 D tRNA-Ile 3500243..3500318 Escherichia coli O127:H6 str. E2348/69 7060883 E2348C_tRNA63 tRNA metY NC_011601.1 3596493 3596569 R tRNA-Met complement(3596493..3596569) Escherichia coli O127:H6 str. E2348/69 7063417 E2348C_tRNA64 tRNA leuU NC_011601.1 3600350 3600436 R tRNA-Leu complement(3600350..3600436) Escherichia coli O127:H6 str. E2348/69 7064607 E2348C_tRNA65 tRNA thrV NC_011601.1 3692816 3692891 R tRNA-Thr complement(3692816..3692891) Escherichia coli O127:H6 str. E2348/69 7064530 E2348C_tRNA66 tRNA gltV_1 NC_011601.1 3696214 3696289 R tRNA-Glu complement(3696214..3696289) Escherichia coli O127:H6 str. E2348/69 7064536 E2348C_tRNA67 tRNA proK NC_011601.1 3956908 3956984 R tRNA-Pro complement(3956908..3956984) Escherichia coli O127:H6 str. E2348/69 7065056 E2348C_tRNA68 tRNA selC NC_011601.1 4102278 4102368 D tRNA-OTHER 4102278..4102368 Escherichia coli O127:H6 str. E2348/69 7061141 E2348C_tRNA69 tRNA gltU NC_011601.1 4240052 4240127 D tRNA-Glu 4240052..4240127 Escherichia coli O127:H6 str. E2348/69 7064544 E2348C_tRNA70 tRNA aspT NC_011601.1 4243495 4243571 D tRNA-Asp 4243495..4243571 Escherichia coli O127:H6 str. E2348/69 7064527 E2348C_tRNA71 tRNA trpT NC_011601.1 4243580 4243655 D tRNA-Trp 4243580..4243655 Escherichia coli O127:H6 str. E2348/69 7062461 E2348C_tRNA72 tRNA argX NC_011601.1 4278123 4278199 D tRNA-Arg 4278123..4278199 Escherichia coli O127:H6 str. E2348/69 7064819 E2348C_tRNA73 tRNA hisR NC_011601.1 4278258 4278333 D tRNA-His 4278258..4278333 Escherichia coli O127:H6 str. E2348/69 7061382 E2348C_tRNA74 tRNA leuT NC_011601.1 4278354 4278439 D tRNA-Leu 4278354..4278439 Escherichia coli O127:H6 str. E2348/69 7062156 E2348C_tRNA75 tRNA proM NC_011601.1 4278482 4278558 D tRNA-Pro 4278482..4278558 Escherichia coli O127:H6 str. E2348/69 7061531 E2348C_tRNA76 tRNA ileT NC_011601.1 4353417 4353493 D tRNA-Ile 4353417..4353493 Escherichia coli O127:H6 str. E2348/69 7064542 E2348C_tRNA77 tRNA alaT NC_011601.1 4353536 4353611 D tRNA-Ala 4353536..4353611 Escherichia coli O127:H6 str. E2348/69 7063524 E2348C_tRNA78 tRNA gltT NC_011601.1 4498928 4499003 D tRNA-Glu 4498928..4499003 Escherichia coli O127:H6 str. E2348/69 7064543 E2348C_tRNA79 tRNA thrU NC_011601.1 4505784 4505859 D tRNA-Thr 4505784..4505859 Escherichia coli O127:H6 str. E2348/69 7062821 E2348C_tRNA80 tRNA tyrU NC_011601.1 4505868 4505952 D tRNA-Tyr 4505868..4505952 Escherichia coli O127:H6 str. E2348/69 7061799 E2348C_tRNA81 tRNA glyT NC_011601.1 4506069 4506143 D tRNA-Gly 4506069..4506143 Escherichia coli O127:H6 str. E2348/69 7062289 E2348C_tRNA82 tRNA thrT NC_011601.1 4506150 4506225 D tRNA-Thr 4506150..4506225 Escherichia coli O127:H6 str. E2348/69 7061723 E2348C_tRNA83 tRNA ileU_1 NC_011601.1 4539093 4539169 D tRNA-Ile 4539093..4539169 Escherichia coli O127:H6 str. E2348/69 7064546 E2348C_tRNA84 tRNA alaU_1 NC_011601.1 4539212 4539287 D tRNA-Ala 4539212..4539287 Escherichia coli O127:H6 str. E2348/69 7063525 E2348C_tRNA85 tRNA pheU NC_011601.1 4710692 4710767 R tRNA-Phe complement(4710692..4710767) Escherichia coli O127:H6 str. E2348/69 7064315 E2348C_tRNA86 tRNA glyV NC_011601.1 4739632 4739707 D tRNA-Gly 4739632..4739707 Escherichia coli O127:H6 str. E2348/69 7062888 E2348C_tRNA87 tRNA glyX NC_011601.1 4739865 4739940 D tRNA-Gly 4739865..4739940 Escherichia coli O127:H6 str. E2348/69 7061725 E2348C_tRNA88 tRNA glyY NC_011601.1 4739976 4740051 D tRNA-Gly 4739976..4740051 Escherichia coli O127:H6 str. E2348/69 7061727 E2348C_tRNA89 tRNA leuX NC_011601.1 4847258 4847342 D tRNA-Leu 4847258..4847342 Escherichia coli O127:H6 str. E2348/69 7064128 E2348C_tRNA90 tRNA leuV NC_011601.1 4930720 4930806 R tRNA-Leu complement(4930720..4930806) Escherichia coli O127:H6 str. E2348/69 7061995 E2348C_tRNA91 tRNA leuP NC_011601.1 4930841 4930927 R tRNA-Leu complement(4930841..4930927) Escherichia coli O127:H6 str. E2348/69 7061533 E2348C_tRNA92 tRNA leuQ NC_011601.1 4930956 4931042 R tRNA-Leu complement(4930956..4931042) Escherichia coli O127:H6 str. E2348/69 7061528 E2348C_rRNA1 rRNA rrsH NC_011601.1 233726 235267 D 16S ribosomal RNA 233726..235267 Escherichia coli O127:H6 str. E2348/69 7061730 E2348C_rRNA2 rRNA rrlH NC_011601.1 235714 238617 D 23S ribosomal RNA 235714..238617 Escherichia coli O127:H6 str. E2348/69 7062432 E2348C_rRNA3 rRNA rrfH NC_011601.1 238716 238835 D 5S ribosomal RNA 238716..238835 Escherichia coli O127:H6 str. E2348/69 7064539 E2348C_rRNA4 rRNA rrfG NC_011601.1 2957055 2957174 R 5S ribosomal RNA complement(2957055..2957174) Escherichia coli O127:H6 str. E2348/69 7065523 E2348C_rRNA5 rRNA rrlG NC_011601.1 2957273 2960176 R 23S ribosomal RNA complement(2957273..2960176) Escherichia coli O127:H6 str. E2348/69 7064531 E2348C_rRNA6 rRNA rrsG NC_011601.1 2960531 2962072 R 16S ribosomal RNA complement(2960531..2962072) Escherichia coli O127:H6 str. E2348/69 7061716 E2348C_rRNA7 rRNA rrfF NC_011601.1 3692659 3692778 R 5S ribosomal RNA complement(3692659..3692778) Escherichia coli O127:H6 str. E2348/69 7064627 E2348C_rRNA8 rRNA rrfD NC_011601.1 3692904 3693023 R 5S ribosomal RNA complement(3692904..3693023) Escherichia coli O127:H6 str. E2348/69 7061800 E2348C_rRNA9 rRNA rrlD NC_011601.1 3693117 3696020 R 23S ribosomal RNA complement(3693117..3696020) Escherichia coli O127:H6 str. E2348/69 7064528 E2348C_rRNA10 rRNA rrsD NC_011601.1 3696375 3697916 R 16S ribosomal RNA complement(3696375..3697916) Escherichia coli O127:H6 str. E2348/69 7061715 E2348C_rRNA11 rRNA rrsC NC_011601.1 4238425 4239966 D 16S ribosomal RNA 4238425..4239966 Escherichia coli O127:H6 str. E2348/69 7064816 E2348C_rRNA12 rRNA rrlC NC_011601.1 4240321 4243224 D 23S ribosomal RNA 4240321..4243224 Escherichia coli O127:H6 str. E2348/69 7061714 E2348C_rRNA13 rRNA rrfC NC_011601.1 4243323 4243442 D 5S ribosomal RNA 4243323..4243442 Escherichia coli O127:H6 str. E2348/69 7064535 E2348C_rRNA14 rRNA rrsA NC_011601.1 4351807 4353348 D 16S ribosomal RNA 4351807..4353348 Escherichia coli O127:H6 str. E2348/69 7064297 E2348C_rRNA15 rRNA rrlA NC_011601.1 4353795 4356698 D 23S ribosomal RNA 4353795..4356698 Escherichia coli O127:H6 str. E2348/69 7062430 E2348C_rRNA16 rRNA rrfA NC_011601.1 4356797 4356916 D 5S ribosomal RNA 4356797..4356916 Escherichia coli O127:H6 str. E2348/69 7064533 E2348C_rRNA17 rRNA rrsB NC_011601.1 4497301 4498842 D 16S ribosomal RNA 4497301..4498842 Escherichia coli O127:H6 str. E2348/69 7060894 E2348C_rRNA18 rRNA rrlB NC_011601.1 4499197 4502100 D 23S ribosomal RNA 4499197..4502100 Escherichia coli O127:H6 str. E2348/69 7061713 E2348C_rRNA19 rRNA rrfB NC_011601.1 4502199 4502318 D 5S ribosomal RNA 4502199..4502318 Escherichia coli O127:H6 str. E2348/69 7064534 E2348C_rRNA20 rRNA rrsE NC_011601.1 4537483 4539024 D 16S ribosomal RNA 4537483..4539024 Escherichia coli O127:H6 str. E2348/69 7063917 E2348C_rRNA21 rRNA rrlE NC_011601.1 4539471 4542374 D 23S ribosomal RNA 4539471..4542374 Escherichia coli O127:H6 str. E2348/69 7062431 E2348C_rRNA22 rRNA rrfE NC_011601.1 4542473 4542592 D 5S ribosomal RNA 4542473..4542592 Escherichia coli O127:H6 str. E2348/69 7064537