-- dump date 20140619_085720 -- class Genbank::CDS -- table cds_note -- id note YP_002268403.1 identified by match to protein family HMM PF02794 YP_002268404.1 identified by match to protein family HMM PF00353; match to protein family HMM PF02382; match to protein family HMM PF08339 YP_002268405.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846 YP_002268406.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843 YP_002268407.1 identified by glimmer; putative YP_002268408.1 identified by match to protein family HMM PF00589 YP_002268410.1 identified by match to protein family HMM PF01051 YP_002268411.1 identified by glimmer; putative YP_002268417.1 identified by match to protein family HMM PF07362 YP_002268418.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002268419.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002268420.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_002268421.1 identified by match to protein family HMM PF00589 YP_002268422.1 identified by glimmer; putative YP_002268423.1 identified by glimmer; putative YP_002268424.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002268425.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002268426.1 identified by glimmer; putative YP_002268427.1 identified by match to protein family HMM PF00376; match to protein family HMM PF01656 YP_002268428.1 SopB YP_002268429.1 identified by match to protein family HMM PF06924 YP_002268432.1 identified by match to protein family HMM PF01555 YP_002268434.1 identified by match to protein family HMM PF07128 YP_002268437.1 identified by match to protein family HMM PF03230 YP_002268440.1 identified by glimmer; putative YP_002268441.1 identified by glimmer; putative YP_002268443.1 identified by glimmer; putative YP_002268444.1 identified by glimmer; putative YP_002268445.1 identified by glimmer; putative YP_002268446.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_002268447.1 identified by match to protein family HMM PF06006 YP_002268448.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_002268449.1 identified by match to protein family HMM PF06290 YP_002268450.1 PsiA YP_002268451.1 identified by match to protein family HMM PF01848 YP_002268452.1 identified by glimmer; putative YP_002268454.1 identified by match to protein family HMM PF04488; match to protein family HMM TIGR01586 YP_002268455.1 identified by match to protein family HMM PF01527; match to protein family HMM PF01695 YP_002268456.1 identified by match to protein family HMM PF07057 YP_002268457.1 identified by match to protein family HMM PF05857; match to protein family HMM TIGR02755 YP_002268458.1 identified by match to protein family HMM PF00561 YP_002268459.1 identified by match to protein family HMM PF05286 YP_002268461.1 identified by match to protein family HMM PF00565 YP_002268462.1 identified by match to protein family HMM PF05321 YP_002268465.1 RepA YP_002268466.1 identified by glimmer; putative YP_002268467.1 identified by glimmer; putative YP_002268468.1 identified by match to protein family HMM PF01402 YP_002268469.1 identified by match to protein family HMM PF05016 YP_002268472.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002268473.1 overlaps another CDS with the same product name YP_002268475.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_002268476.1 identified by match to protein family HMM PF07361 YP_002268477.1 overlaps another CDS with the same product name YP_002268478.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002268479.1 identified by glimmer; putative YP_002268480.1 identified by match to protein family HMM PF02395; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002268482.1 identified by match to protein family HMM PF03811 YP_002268484.1 identified by glimmer; putative YP_002268485.1 identified by glimmer; putative YP_002268486.1 identified by match to protein family HMM PF01522 YP_002268487.1 identified by match to protein family HMM PF00534 YP_002268488.1 identified by match to protein family HMM PF00884 YP_002268489.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_002268490.1 identified by glimmer; putative YP_002268491.1 identified by match to protein family HMM PF01527 YP_002268492.1 identified by match to protein family HMM PF05717 YP_002268493.1 identified by match to protein family HMM PF03050 YP_002268495.1 identified by glimmer; putative YP_002268497.1 identified by match to protein family HMM TIGR01713 YP_002268498.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517 YP_002268499.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533 YP_002268500.1 identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120 YP_002268501.1 identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532 YP_002268502.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532 YP_002268503.1 identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532 YP_002268504.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532 YP_002268505.1 identified by match to protein family HMM PF03934 YP_002268506.1 identified by match to protein family HMM PF05134; match to protein family HMM TIGR01709 YP_002268507.1 identified by match to protein family HMM PF04612 YP_002268508.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750 YP_002268509.1 identified by match to protein family HMM PF09691; match to protein family HMM TIGR01004 YP_002268510.1 identified by match to protein family HMM PF01527 YP_002268511.1 identified by match to protein family HMM PF01051 YP_002268513.1 identified by glimmer; putative YP_002268515.1 identified by glimmer; putative YP_002268516.1 identified by match to protein family HMM PF04610 YP_002268521.1 identified by match to protein family HMM PF05101 YP_002268522.1 identified by match to protein family HMM PF03135 YP_002268523.1 identified by match to protein family HMM PF04335 YP_002268524.1 identified by match to protein family HMM PF03524 YP_002268525.1 identified by match to protein family HMM PF03743 YP_002268526.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02788 YP_002268527.1 identified by match to protein family HMM PF02534 YP_002268530.1 identified by glimmer; putative YP_002268532.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056 YP_002268533.1 identified by glimmer; putative YP_002268534.1 identified by glimmer; putative YP_002268537.1 identified by glimmer; putative YP_002268538.1 identified by glimmer; putative YP_002268539.1 identified by glimmer; putative YP_002268540.1 identified by match to protein family HMM PF00589 YP_002268543.1 identified by glimmer; putative YP_002268544.1 identified by glimmer; putative YP_002268545.1 identified by glimmer; putative YP_002268546.1 identified by match to protein family HMM PF03432 YP_002268547.1 identified by match to protein family HMM PF01402 YP_002268548.1 identified by glimmer; putative YP_002268551.1 identified by match to protein family HMM PF03681 YP_002268552.1 identified by match to protein family HMM PF07927 YP_002268553.1 identified by glimmer; putative YP_002268556.1 identified by glimmer; putative YP_002268559.1 identified by glimmer; putative YP_002268562.1 identified by glimmer; putative YP_002268563.1 identified by glimmer; putative YP_002268564.1 identified by glimmer; putative YP_002268609.1 identified by glimmer YP_002268610.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002268611.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002268612.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002268614.1 identified by match to protein family HMM PF03883 YP_002268615.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002268616.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_002268617.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002268618.1 identified by match to protein family HMM PF01184 YP_002268619.1 identified by match to protein family HMM PF03667 YP_002268621.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002268622.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002268623.1 identified by match to protein family HMM PF01848 YP_002268624.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002268625.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_002268627.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002268628.1 identified by match to protein family HMM PF00419 YP_002268629.1 identified by glimmer YP_002268630.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002268631.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002268632.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002268633.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002268634.1 identified by match to protein family HMM PF00254 YP_002268635.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002268636.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_002268637.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002268638.1 identified by glimmer YP_002268639.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002268640.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002268641.1 identified by glimmer YP_002268642.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons YP_002268643.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_002268644.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_002268645.1 identified by match to protein family HMM PF00501 YP_002268646.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_002268647.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_002268648.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_002268649.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_002268650.1 involved in electron transfer during carnitine metabolism YP_002268651.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_002268653.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002268654.1 Required for full activity of KefC, a potassium-proton antiporter YP_002268655.1 transport system that facilitates potassium-efflux YP_002268656.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_002268657.1 identified by match to protein family HMM PF07362 YP_002268658.1 identified by match to protein family HMM PF01845 YP_002268659.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_002268660.1 protein associated with Co2+ and Mg2+ efflux YP_002268661.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002268662.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002268663.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_002268664.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002268665.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002268666.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_002268667.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_002268668.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_002268669.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002268670.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_002268671.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_002268672.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_002268673.1 identified by match to protein family HMM PF09335 YP_002268674.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_002268675.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002268676.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_002268678.1 activates sgrS under glucose-phosphate stress conditions YP_002268679.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002268680.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002268681.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002268682.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002268684.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_002268685.1 identified by glimmer YP_002268686.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_002268687.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002268688.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002268689.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002268690.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002268691.1 membrane bound cell division protein at septum containing leucine zipper motif YP_002268692.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002268693.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002268694.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002268695.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002268696.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002268697.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_002268698.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002268699.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002268700.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002268701.1 involved in septum formation YP_002268702.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_002268703.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002268704.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002268705.1 secM translational pause allows for the initiation of secA translation YP_002268706.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002268707.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586 YP_002268708.1 identified by match to protein family HMM PF03884 YP_002268709.1 identified by match to protein family HMM PF07072 YP_002268710.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002268711.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002268712.1 identified by match to protein family HMM PF00482 YP_002268713.1 identified by match to protein family HMM PF00437 YP_002268714.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002268715.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002268716.1 identified by match to protein family HMM PF01510 YP_002268717.1 involved in regulation of beta-lactamase; signaling protein YP_002268718.1 identified by match to protein family HMM PF00324 YP_002268719.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002268720.1 identified by glimmer YP_002268721.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002268722.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_002268723.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002268725.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002268726.1 identified by match to protein family HMM PF06062 YP_002268727.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002268728.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002268730.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_002268732.1 identified by match to protein family HMM PF01011; match to protein family HMM TIGR03074 YP_002268733.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002268734.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_002268735.1 identified by match to protein family HMM PF00005 YP_002268736.1 identified by match to protein family HMM PF01061 YP_002268737.1 identified by match to protein family HMM PF03610 YP_002268738.1 identified by match to protein family HMM PF01522 YP_002268739.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002268740.1 identified by glimmer YP_002268741.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002268742.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002268743.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002268744.1 identified by match to protein family HMM PF00419 YP_002268745.1 identified by match to protein family HMM PF00419 YP_002268748.1 similar to the fimbrial usher protein PapC YP_002268749.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002268750.1 identified by match to protein family HMM PF00419 YP_002268751.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_002268752.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_002268753.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_002268754.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420 YP_002268755.1 Regulatory factor involved in maltose metabolism YP_002268756.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_002268757.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002268758.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_002268759.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_002268760.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_002268761.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_002268762.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002268763.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002268764.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_002268765.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_002268766.1 identified by match to protein family HMM PF03458 YP_002268767.1 solute binding component of the vitamin B12 transport system BtuCDF YP_002268768.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002268769.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_002268770.1 protease Do; required at high temperature; degrades damaged proteins YP_002268771.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_002268773.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002268774.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002268775.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002268776.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002268778.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002268779.1 Catalyzes the phosphorylation of UMP to UDP YP_002268780.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002268781.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002268782.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_002268783.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_002268784.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_002268785.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_002268786.1 identified by match to protein family HMM PF03938 YP_002268787.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002268788.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002268789.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002268790.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_002268791.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002268792.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002268793.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002268794.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002268795.1 identified by match to protein family HMM PF00903 YP_002268796.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_002268797.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_002268798.1 identified by match to protein family HMM PF06786 YP_002268799.1 identified by match to protein family HMM PF07152 YP_002268800.1 identified by match to protein family HMM PF00472 YP_002268801.1 identified by match to protein family HMM PF04170 YP_002268803.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002268804.1 identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_002268806.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_002268807.1 part of the MetNIQ methionine uptake system YP_002268808.1 part of the metNIQ transport system for methionine YP_002268809.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_002268810.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_002268811.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002268812.1 identified by match to protein family HMM PF03372 YP_002268813.1 identified by match to protein family HMM PF01209; match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002268814.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_002268815.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_002268816.1 identified by match to protein family HMM PF08241 YP_002268817.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002268818.1 3'-5' exonuclease of DNA polymerase III YP_002268821.1 identified by match to protein family HMM PF06812 YP_002268822.1 identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362 YP_002268823.1 identified by match to protein family HMM TIGR03360 YP_002268824.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345 YP_002268825.1 identified by match to protein family HMM TIGR03349 YP_002268826.1 identified by match to protein family HMM PF05936; match to protein family HMM TIGR03353 YP_002268827.1 identified by match to protein family HMM TIGR03352 YP_002268828.1 identified by match to protein family HMM TIGR03354 YP_002268829.1 identified by match to protein family HMM PF06996; match to protein family HMM TIGR03347 YP_002268830.1 identified by match to protein family HMM PF05947; match to protein family HMM TIGR03359 YP_002268831.1 identified by match to protein family HMM PF04965; match to protein family HMM TIGR03357 YP_002268832.1 identified by glimmer YP_002268833.1 identified by match to protein family HMM PF05591; match to protein family HMM TIGR03358 YP_002268834.1 identified by glimmer YP_002268835.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002268836.1 identified by glimmer YP_002268837.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_002268838.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002268839.1 identified by match to protein family HMM PF00023 YP_002268840.1 identified by match to protein family HMM PF03527 YP_002268842.1 identified by glimmer YP_002268843.1 identified by match to protein family HMM PF01609 YP_002268844.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593 YP_002268845.1 identified by glimmer YP_002268846.1 identified by match to protein family HMM PF01609 YP_002268847.1 identified by match to protein family HMM PF00795 YP_002268848.1 inactivates vertebrate C-type lysozyme YP_002268849.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_002268850.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_002268851.1 identified by match to protein family HMM PF00310 YP_002268852.1 identified by match to protein family HMM PF06104 YP_002268853.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_002268854.1 identified by match to protein family HMM PF00877 YP_002268855.1 identified by glimmer YP_002268856.1 identified by match to protein family HMM PF00771 YP_002268857.1 identified by match to protein family HMM PF00691 YP_002268858.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002268859.1 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552 YP_002268860.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function YP_002268861.1 identified by match to protein family HMM PF00583 YP_002268863.1 similar to release factor 1 and 2 YP_002268864.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_002268865.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_002268866.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002268867.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_002268868.1 identified by match to protein family HMM PF00267 YP_002268869.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002268870.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002268871.1 identified by match to protein family HMM PF00589 YP_002268872.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002268873.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002268874.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_002268875.1 identified by match to protein family HMM PF09048 YP_002268876.1 identified by match to protein family HMM PF05269 YP_002268878.1 identified by match to protein family HMM PF07484 YP_002268879.1 identified by match to protein family HMM PF02413 YP_002268880.1 identified by match to protein family HMM PF02413 YP_002268882.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002268884.1 identified by match to protein family HMM PF00165 YP_002268886.1 identified by match to protein family HMM PF00589 YP_002268890.1 identified by match to protein family HMM PF07455 YP_002268892.1 identified by match to protein family HMM PF05930 YP_002268896.1 identified by match to protein family HMM PF03288; match to protein family HMM PF08273; match to protein family HMM PF08706; match to protein family HMM TIGR01613 YP_002268898.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002268899.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_002268902.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002268904.1 identified by match to protein family HMM PF07690 YP_002268905.1 identified by match to protein family HMM PF02625 YP_002268906.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738 YP_002268907.1 identified by match to protein family HMM PF00941 YP_002268908.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; match to protein family HMM TIGR01409 YP_002268909.1 identified by match to protein family HMM PF07274 YP_002268910.1 identified by glimmer YP_002268916.1 identified by match to protein family HMM PF00196 YP_002268917.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_002268918.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002268919.1 identified by match to protein family HMM PF05717 YP_002268920.1 identified by match to protein family HMM PF03050 YP_002268921.1 identified by match to protein family HMM PF00724 YP_002268923.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002268926.1 identified by match to protein family HMM PF00248 YP_002268927.1 identified by match to protein family HMM PF02369 YP_002268928.1 identified by match to protein family HMM PF06445 YP_002268929.1 identified by match to protein family HMM PF00248 YP_002268930.1 identified by match to protein family HMM PF04224 YP_002268931.1 identified by match to protein family HMM PF07338 YP_002268932.1 Involved in disulfide oxidoreductase activity and electron transport YP_002268933.1 identified by match to protein family HMM PF00165 YP_002268934.1 identified by glimmer YP_002268935.1 identified by match to protein family HMM PF02754 YP_002268936.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_002268937.1 identified by match to protein family HMM PF02589 YP_002268938.1 identified by glimmer YP_002268939.1 identified by glimmer YP_002268942.1 identified by glimmer YP_002268943.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_002268944.1 catalyzes the formation of betaine from betaine aldehyde YP_002268945.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_002268946.1 proton-motive-force-driven choline transporter YP_002268947.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002268948.1 identified by match to protein family HMM PF00196; match to protein family HMM PF00563 YP_002268949.1 identified by match to protein family HMM PF00023 YP_002268951.1 identified by match to protein family HMM PF06263 YP_002268952.1 identified by match to protein family HMM PF06545 YP_002268955.1 identified by match to protein family HMM PF00696 YP_002268956.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_002268957.1 identified by match to protein family HMM PF04266 YP_002268958.1 identified by glimmer YP_002268960.1 identified by match to protein family HMM PF00005 YP_002268961.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF02653 YP_002268962.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF02653 YP_002268963.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002268965.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002268966.1 identified by match to protein family HMM PF07338 YP_002268967.1 identified by glimmer YP_002268968.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329 YP_002268969.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_002268970.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_002268971.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_002268972.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_002268975.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_002268976.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002268977.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_002268978.1 identified by match to protein family HMM PF00484 YP_002268979.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_002268980.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_002268981.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown YP_002268982.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_002268983.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_002268984.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_002268985.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01965 YP_002268987.1 activator of 3-phenylpropionic acid catabolism YP_002268988.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_002268989.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family YP_002268990.1 identified by match to protein family HMM PF00561 YP_002268991.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_002268992.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_002268993.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_002268994.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895 YP_002268996.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_002268997.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_002268999.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import YP_002269000.1 identified by match to protein family HMM PF00528 YP_002269001.1 identified by match to protein family HMM PF01547 YP_002269002.1 identified by match to protein family HMM PF07690 YP_002269003.1 identified by match to protein family HMM PF02518; match to protein family HMM PF05231; match to protein family HMM PF07730 YP_002269004.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002269005.1 identified by glimmer YP_002269006.1 with TauB and TauC is responsible for taurine uptake. YP_002269007.1 Part of the ABC transporter complex tauABC involved in taurine import YP_002269008.1 identified by match to protein family HMM PF00528 YP_002269009.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_002269010.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002269011.1 identified by glimmer YP_002269012.1 this protein has no known enzymatic function YP_002269013.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_002269014.1 identified by match to protein family HMM PF07759 YP_002269017.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002269018.1 identified by glimmer YP_002269019.1 identified by glimmer YP_002269021.1 identified by match to protein family HMM PF00245 YP_002269022.1 identified by match to protein family HMM PF07769 YP_002269023.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis YP_002269024.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002269025.1 identified by match to protein family HMM PF02639 YP_002269026.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002269028.1 identified by match to protein family HMM PF07302 YP_002269029.1 identified by match to protein family HMM PF06865 YP_002269030.1 identified by glimmer YP_002269031.1 Required for efficient pilin antigenic variation YP_002269032.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_002269033.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_002269034.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_002269035.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_002269036.1 identified by glimmer YP_002269037.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_002269038.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002269040.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002269041.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_002269042.1 identified by match to protein family HMM PF00128 YP_002269043.1 identified by glimmer YP_002269044.1 identified by glimmer YP_002269045.1 identified by glimmer YP_002269046.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_002269047.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002269048.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002269049.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002269050.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002269051.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002269052.1 identified by match to protein family HMM PF03693; match to protein family HMM TIGR02606 YP_002269053.1 identified by match to protein family HMM PF05016 YP_002269054.1 identified by match to protein family HMM PF01844 YP_002269055.1 identified by match to protein family HMM PF03502 YP_002269057.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002269058.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_002269059.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002269060.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002269061.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002269062.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002269063.1 identified by match to protein family HMM PF00805 YP_002269064.1 identified by match to protein family HMM PF00248 YP_002269065.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002269066.1 identified by match to protein family HMM PF00348 YP_002269067.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002269068.1 identified by glimmer YP_002269069.1 Required for the synthesis of the thiazole moiety YP_002269070.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_002269071.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002269072.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002269073.1 identified by match to protein family HMM PF07690 YP_002269074.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002269075.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02847 YP_002269076.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842 YP_002269077.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843 YP_002269078.1 identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433 YP_002269079.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_002269080.1 identified by match to protein family HMM PF03923 YP_002269081.1 identified by glimmer YP_002269082.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_002269083.1 identified by glimmer YP_002269084.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002269085.1 binds and unfolds substrates as part of the ClpXP protease YP_002269086.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_002269087.1 histone-like DNA-binding protein YP_002269088.1 identified by match to protein family HMM PF00639 YP_002269089.1 identified by match to protein family HMM TIGR00426 YP_002269090.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_002269091.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_002269092.1 identified by match to protein family HMM PF00496 YP_002269093.1 identified by glimmer YP_002269094.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002269095.1 identified by glimmer YP_002269096.1 identified by match to protein family HMM PF01037 YP_002269097.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002269098.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002269099.1 identified by glimmer YP_002269100.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_002269101.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_002269102.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189 YP_002269103.1 identified by glimmer YP_002269105.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_002269106.1 identified by match to protein family HMM PF07237 YP_002269107.1 identified by match to protein family HMM PF00563 YP_002269109.1 identified by match to protein family HMM PF00132 YP_002269110.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_002269112.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002269113.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002269114.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_002269115.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_002269117.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_002269118.1 identified by match to protein family HMM PF04304 YP_002269119.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002269120.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002269121.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002269122.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002269123.1 molecular chaperone YP_002269124.1 identified by glimmer YP_002269125.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002269126.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002269127.1 identified by match to protein family HMM PF07859 YP_002269128.1 identified by match to protein family HMM PF00294 YP_002269129.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_002269130.1 identified by match to protein family HMM PF07690 YP_002269131.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_002269132.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_002269133.1 identified by match to protein family HMM PF07446 YP_002269134.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_002269135.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002269136.1 catalyzes the formation of glutamate from glutamine YP_002269137.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002269138.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844 YP_002269140.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR03375 YP_002269141.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843 YP_002269142.1 activator of copper-responsive regulon genes YP_002269143.1 identified by glimmer YP_002269145.1 identified by match to protein family HMM PF03895 YP_002269146.1 identified by glimmer YP_002269148.1 identified by match to protein family HMM PF01957 YP_002269149.1 identified by match to protein family HMM PF01145 YP_002269150.1 identified by match to protein family HMM PF00005 YP_002269151.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_002269152.1 identified by match to protein family HMM PF00085 YP_002269153.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002269154.1 identified by match to protein family HMM PF00657 YP_002269155.1 identified by match to protein family HMM PF00005 YP_002269156.1 identified by match to protein family HMM PF02687 YP_002269157.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002269158.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_002269159.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_002269160.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_002269161.1 regulates operons involved in the utilization of allantoin YP_002269162.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_002269163.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234 YP_002269164.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505 YP_002269165.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_002269166.1 identified by match to protein family HMM PF00860 YP_002269167.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002269168.1 identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214 YP_002269169.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002269170.1 identified by match to protein family HMM PF02615; match to protein family HMM TIGR03175 YP_002269171.1 multicopy suppressor of dominant negative ftsH mutations YP_002269172.1 identified by match to protein family HMM PF06545 YP_002269174.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746 YP_002269175.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002269176.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002269177.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_002269178.1 identified by match to protein family HMM PF00160 YP_002269179.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002269180.1 identified by match to protein family HMM PF04307 YP_002269182.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002269183.1 identified by match to protein family HMM PF00419 YP_002269184.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002269185.1 identified by match to protein family HMM PF00577 YP_002269188.1 activates the production of the major fimbrae protein FimA YP_002269189.1 identified by glimmer YP_002269190.1 identified by match to protein family HMM PF00165 YP_002269192.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002269193.1 identified by match to protein family HMM PF05157 YP_002269194.1 identified by match to protein family HMM PF01609 YP_002269196.1 identified by match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002269197.1 identified by match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002269198.1 identified by match to protein family HMM PF08786 YP_002269199.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_002269200.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_002269201.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_002269202.1 identified by glimmer YP_002269203.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_002269205.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_002269206.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914 YP_002269207.1 identified by match to protein family HMM PF00324 YP_002269208.1 identified by match to protein family HMM PF00924 YP_002269209.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_002269210.1 identified by match to protein family HMM PF04237 YP_002269211.1 identified by match to protein family HMM PF06643 YP_002269212.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_002269213.1 identified by glimmer YP_002269214.1 identified by match to protein family HMM PF01848 YP_002269215.1 identified by match to protein family HMM PF01648 YP_002269216.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002269217.1 identified by glimmer YP_002269218.1 identified by match to protein family HMM PF00756 YP_002269219.1 identified by match to protein family HMM PF03621 YP_002269220.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_002269221.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_002269222.1 with FepBDE is involved in the transport of ferric enterobactin YP_002269223.1 with FepBCD is involved in the transport of ferric enterobactin YP_002269224.1 with FepBCG is involved in the transport of ferric enterobactin YP_002269225.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_002269226.1 with FepCDG is involved in the transport of ferric enterobactin YP_002269227.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002269228.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_002269229.1 identified by match to protein family HMM PF00550; match to protein family HMM PF00857 YP_002269230.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_002269231.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002269232.1 identified by match to protein family HMM PF02554 YP_002269233.1 identified by match to protein family HMM PF04328 YP_002269234.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_002269235.1 catalyzes the transfer of an amino moiety YP_002269236.1 identified by match to protein family HMM PF02195 YP_002269237.1 identified by match to protein family HMM PF01507 YP_002269238.1 identified by match to protein family HMM PF00126 YP_002269239.1 Involved in disulfide bond formation YP_002269240.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_002269241.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140 YP_002269242.1 identified by match to protein family HMM PF00582 YP_002269243.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002269244.1 identified by glimmer YP_002269245.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_002269246.1 identified by glimmer YP_002269247.1 identified by match to protein family HMM PF00445 YP_002269248.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_002269249.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_002269250.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_002269251.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_002269252.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_002269253.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_002269254.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_002269255.1 identified by match to protein family HMM PF02518 YP_002269256.1 regulates the expression of citAB in citrate fermentation YP_002269257.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_002269258.1 catalyzes the transfer of palmitate to lipid A YP_002269259.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_002269260.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002269261.1 identified by match to protein family HMM PF00795 YP_002269262.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002269263.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002269264.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002269265.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_002269266.1 identified by match to protein family HMM PF04359 YP_002269267.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_002269269.1 identified by match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413 YP_002269270.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210 YP_002269271.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_002269272.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002269273.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002269274.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR03162 YP_002269275.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002269276.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002269277.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_002269278.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002269279.1 identified by match to protein family HMM PF07295 YP_002269280.1 identified by match to protein family HMM PF06889 YP_002269281.1 identified by match to protein family HMM PF00226 YP_002269282.1 identified by match to protein family HMM PF08238 YP_002269283.1 identified by match to protein family HMM PF06889 YP_002269284.1 identified by glimmer YP_002269285.1 identified by match to protein family HMM PF00012 YP_002269286.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_002269287.1 identified by match to protein family HMM PF00005 YP_002269288.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002269289.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002269290.1 identified by match to protein family HMM PF00497 YP_002269291.1 identified by glimmer YP_002269292.1 Transfers the fatty acyl group on membrane lipoproteins YP_002269293.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471 YP_002269294.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002269295.1 identified by match to protein family HMM PF02562 YP_002269296.1 identified by glimmer YP_002269297.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002269298.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_002269299.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_002269301.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460 YP_002269302.1 identified by match to protein family HMM PF00480 YP_002269303.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_002269304.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002269305.1 identified by glimmer YP_002269306.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002269307.1 identified by glimmer YP_002269308.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002269311.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_002269312.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002269313.1 identified by match to protein family HMM PF01402 YP_002269314.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819 YP_002269315.1 negative modulator of the initiation of chromosome replication YP_002269316.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002269317.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_002269318.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002269319.1 identified by glimmer YP_002269320.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_002269321.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_002269322.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_002269323.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002269324.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002269326.1 identified by glimmer YP_002269327.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002269328.1 identified by glimmer YP_002269329.1 identified by match to protein family HMM PF01609 YP_002269330.1 identified by match to protein family HMM PF08349 YP_002269331.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_002269332.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002269333.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002269334.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_002269335.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_002269336.1 identified by match to protein family HMM PF03746 YP_002269337.1 identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082 YP_002269339.1 identified by match to protein family HMM PF00345 YP_002269340.1 identified by match to protein family HMM PF00577 YP_002269341.1 identified by match to protein family HMM PF00419 YP_002269342.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_002269345.1 identified by match to protein family HMM TIGR02968 YP_002269346.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002269347.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002269349.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002269350.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002269351.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002269352.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002269354.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002269355.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_002269356.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002269357.1 identified by match to protein family HMM PF00375 YP_002269360.1 identified by match to protein family HMM PF05034; match to protein family HMM PF07476; match to protein family HMM TIGR01502 YP_002269361.1 identified by match to protein family HMM PF06368; match to protein family HMM TIGR01503 YP_002269362.1 identified by match to protein family HMM TIGR01319 YP_002269363.1 converts methylaspartate to L-glutamate YP_002269364.1 identified by glimmer YP_002269365.1 identified by glimmer YP_002269366.1 identified by match to protein family HMM PF01654 YP_002269367.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002269368.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106 YP_002269369.1 identified by match to protein family HMM TIGR02112 YP_002269370.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_002269371.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002269372.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002269373.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_002269374.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002269375.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802 YP_002269376.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_002269377.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002269378.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002269379.1 involved in zinc efflux across the cytoplasmic membrane YP_002269381.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002269382.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002269383.1 identified by glimmer YP_002269384.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_002269385.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002269386.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_002269387.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002269388.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_002269389.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_002269391.1 with ModCB is involved in the high-affinity transport of molybdate YP_002269392.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_002269393.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002269394.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_002269395.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_002269396.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002269397.1 identified by glimmer YP_002269398.1 identified by match to protein family HMM PF04303 YP_002269399.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_002269400.1 identified by match to protein family HMM PF00330 YP_002269401.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_002269402.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM PF09003 YP_002269403.1 identified by glimmer YP_002269407.1 identified by match to protein family HMM PF07131 YP_002269408.1 identified by match to protein family HMM PF09588 YP_002269409.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913 YP_002269410.1 identified by match to protein family HMM PF05766 YP_002269411.1 identified by match to protein family HMM PF00149 YP_002269413.1 identified by match to protein family HMM PF06323 YP_002269416.1 identified by match to protein family HMM PF00959 YP_002269417.1 identified by match to protein family HMM PF03245 YP_002269419.1 identified by match to protein family HMM PF07278 YP_002269420.1 identified by match to protein family HMM PF05876 YP_002269422.1 identified by match to protein family HMM PF00574 YP_002269425.1 identified by match to protein family HMM PF06763 YP_002269426.1 identified by match to protein family HMM PF06141 YP_002269427.1 identified by match to protein family HMM PF02368 YP_002269428.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002269429.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002269430.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002269431.1 identified by match to protein family HMM PF05939 YP_002269432.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002269433.1 identified by match to protein family HMM PF00877 YP_002269434.1 identified by match to protein family HMM PF06805 YP_002269435.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002269436.1 identified by match to protein family HMM PF06316 YP_002269437.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002269438.1 identified by match to protein family HMM PF06820 YP_002269442.1 YbhB; similar to rat and human kinase inhibitory proteins YP_002269443.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002269444.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433 YP_002269445.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002269446.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_002269447.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002269448.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002269449.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002269450.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002269451.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667 YP_002269452.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002269453.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002269454.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002269455.1 identified by match to protein family HMM PF01027 YP_002269456.1 identified by match to protein family HMM PF01027 YP_002269458.1 identified by match to protein family HMM PF00614 YP_002269459.1 identified by match to protein family HMM PF03372 YP_002269461.1 identified by match to protein family HMM PF01061 YP_002269462.1 identified by match to protein family HMM PF01061 YP_002269463.1 identified by match to protein family HMM PF00005 YP_002269464.1 identified by match to protein family HMM PF00529 YP_002269465.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209 YP_002269466.1 this helicase is not essential cell growth YP_002269467.1 identified by glimmer YP_002269468.1 identified by glimmer YP_002269469.1 helicase involved in DNA repair and perhaps also replication YP_002269470.1 identified by match to protein family HMM PF02885 YP_002269471.1 identified by match to protein family HMM PF02615 YP_002269472.1 identified by match to protein family HMM PF07338 YP_002269473.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_002269474.1 identified by match to protein family HMM PF03171 YP_002269475.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_002269476.1 identified by match to protein family HMM PF07338 YP_002269477.1 identified by match to protein family HMM PF05971 YP_002269478.1 identified by match to protein family HMM PF00924 YP_002269479.1 similar to ATP-binding component of ABC transporters YP_002269480.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002269481.1 similar to periplasmic-binding component of ABC transporters YP_002269482.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_002269483.1 identified by match to protein family HMM PF00892 YP_002269484.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_002269485.1 identified by match to protein family HMM PF00884 YP_002269486.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_002269487.1 identified by match to protein family HMM PF03600 YP_002269488.1 identified by match to protein family HMM PF03734 YP_002269489.1 identified by match to protein family HMM PF00005 YP_002269490.1 identified by match to protein family HMM PF07350 YP_002269491.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002269492.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002269493.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002269494.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_002269495.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_002269496.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_002269497.1 identified by match to protein family HMM PF00496 YP_002269498.1 identified by match to protein family HMM PF00528 YP_002269499.1 identified by match to protein family HMM PF00528 YP_002269500.1 identified by match to protein family HMM PF00563 YP_002269501.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002269502.1 identified by match to protein family HMM PF01381 YP_002269503.1 identified by match to protein family HMM PF06296 YP_002269504.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_002269505.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_002269506.1 identified by match to protein family HMM PF07995 YP_002269507.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002269508.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002269509.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002269510.1 identified by match to protein family HMM PF01569 YP_002269511.1 identified by match to protein family HMM PF07690 YP_002269513.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002269514.1 identified by match to protein family HMM PF07690 YP_002269515.1 identified by match to protein family HMM PF00440 YP_002269516.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_002269518.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_002269519.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_002269520.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_002269521.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_002269523.1 identified by glimmer YP_002269524.1 identified by match to protein family HMM PF01547 YP_002269525.1 part of the PotFGHI ATP-dependent putrescine transporter YP_002269526.1 identified by match to protein family HMM PF00528 YP_002269527.1 identified by match to protein family HMM PF00528 YP_002269529.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_002269530.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002269531.1 identified by match to protein family HMM PF00884 YP_002269532.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002269534.1 with ArtPQJI acts to transport arginine across the inner membrane YP_002269535.1 with ArtPMJI transports arginine across the inner membrane YP_002269536.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002269537.1 With ArtMQJI transports arginine across the inner membrane YP_002269538.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_002269539.1 identified by glimmer YP_002269540.1 identified by match to protein family HMM PF01906 YP_002269541.1 identified by match to protein family HMM PF01510 YP_002269542.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002269543.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368 YP_002269544.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_002269545.1 catalyzes the formation of acetate from pyruvate YP_002269546.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002269547.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002269548.1 identified by match to protein family HMM PF03956 YP_002269549.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_002269551.1 identified by match to protein family HMM PF04393 YP_002269552.1 confers macrolide resistance via active drug efflux YP_002269553.1 with MacA is involved in the export of macrolide YP_002269554.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible YP_002269555.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002269556.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_002269557.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002269558.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_002269559.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002269560.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002269561.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_002269562.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_002269563.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_002269564.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002269565.1 identified by match to protein family HMM PF00004 YP_002269566.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002269567.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002269568.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002269569.1 identified by match to protein family HMM PF04976 YP_002269570.1 identified by match to protein family HMM PF00857 YP_002269571.1 identified by glimmer YP_002269572.1 identified by match to protein family HMM PF07690 YP_002269573.1 identified by match to protein family HMM PF00324 YP_002269574.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_002269575.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002269576.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_002269577.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR00702 YP_002269578.1 identified by match to protein family HMM PF04239 YP_002269579.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002269580.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002269581.1 identified by match to protein family HMM PF01435 YP_002269582.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002269583.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002269584.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002269585.1 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002269586.1 involved in the transport of lipid A across the inner membrane YP_002269587.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_002269588.1 identified by match to protein family HMM PF06224 YP_002269589.1 identified by match to protein family HMM PF03966 YP_002269590.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002269592.1 identified by match to protein family HMM PF02698 YP_002269593.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002269594.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002269595.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002269596.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002269597.1 identified by match to protein family HMM PF01471 YP_002269598.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409 YP_002269599.1 identified by match to protein family HMM PF00753 YP_002269600.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002269601.1 outer membrane porin F; 1a; Ia; b YP_002269602.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002269603.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002269604.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 YP_002269605.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_002269606.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_002269607.1 catalyzes the release of sulfite from alkanesulfonates YP_002269608.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_002269609.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; match to protein family HMM TIGR03567 YP_002269610.1 identified by match to protein family HMM PF00419 YP_002269611.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002269612.1 identified by match to protein family HMM PF00419 YP_002269613.1 identified by match to protein family HMM PF00419 YP_002269614.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_002269615.1 identified by match to protein family HMM PF07126 YP_002269616.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476 YP_002269617.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002269618.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002269619.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_002269620.1 identified by match to protein family HMM PF02470 YP_002269621.1 identified by match to protein family HMM PF03886 YP_002269622.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_002269623.1 identified by match to protein family HMM PF05362 YP_002269624.1 identified by match to protein family HMM PF06303 YP_002269625.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_002269626.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623 YP_002269627.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994 YP_002269628.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667 YP_002269629.1 identified by match to protein family HMM PF03733 YP_002269630.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002269631.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002269633.1 identified by glimmer YP_002269634.1 identified by match to protein family HMM PF02629 YP_002269635.1 identified by match to protein family HMM PF08755; match to protein family HMM TIGR02097 YP_002269636.1 identified by match to protein family HMM PF03602 YP_002269637.1 catalyzes the hydrolysis of acylphosphate YP_002269638.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_002269639.1 identified by match to protein family HMM PF01027 YP_002269642.1 identified by match to protein family HMM PF07358 YP_002269643.1 identified by match to protein family HMM PF05358 YP_002269650.1 identified by match to protein family HMM PF06254 YP_002269653.1 identified by match to protein family HMM PF01695 YP_002269654.1 identified by match to protein family HMM PF07789 YP_002269655.1 identified by match to protein family HMM PF06163 YP_002269657.1 identified by match to protein family HMM PF06914 YP_002269658.1 identified by match to protein family HMM PF05866 YP_002269660.1 identified by match to protein family HMM PF02517 YP_002269661.1 identified by glimmer YP_002269662.1 identified by match to protein family HMM PF00165 YP_002269663.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002269664.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002269665.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002269667.1 identified by match to protein family HMM PF03245 YP_002269668.1 identified by glimmer YP_002269669.1 identified by match to protein family HMM PF00959 YP_002269671.1 identified by match to protein family HMM PF04971 YP_002269672.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002269673.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002269677.1 identified by match to protein family HMM PF05717 YP_002269678.1 identified by match to protein family HMM PF03050 YP_002269680.1 identified by match to protein family HMM PF02831 YP_002269681.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002269682.1 identified by match to protein family HMM PF01343 YP_002269683.1 identified by match to protein family HMM PF02924 YP_002269685.1 identified by match to protein family HMM PF02368 YP_002269686.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002269687.1 identified by match to protein family HMM TIGR01715 YP_002269688.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002269689.1 identified by match to protein family HMM PF05939 YP_002269690.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002269691.1 identified by match to protein family HMM PF00877 YP_002269692.1 identified by match to protein family HMM PF06805 YP_002269693.1 identified by match to protein family HMM PF00080 YP_002269694.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002269695.1 identified by match to protein family HMM PF06316 YP_002269696.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002269697.1 identified by match to protein family HMM PF06820 YP_002269698.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_002269699.1 involved in hydrogen cycling during fermentative growth YP_002269700.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_002269701.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_002269702.1 involved in processing hydrogenases HyaA and HyaB YP_002269703.1 identified by match to protein family HMM PF04809 YP_002269704.1 identified by match to protein family HMM PF01654 YP_002269705.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002269706.1 identified by match to protein family HMM PF00328 YP_002269707.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01007 YP_002269708.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk YP_002269709.1 identified by match to protein family HMM PF02563 YP_002269710.1 identified by match to protein family HMM PF06082 YP_002269711.1 identified by match to protein family HMM PF06251 YP_002269714.1 identified by match to protein family HMM PF00313 YP_002269715.1 identified by match to protein family HMM PF00313 YP_002269716.1 identified by glimmer YP_002269718.1 identified by match to protein family HMM PF00037 YP_002269719.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_002269720.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_002269721.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_002269722.1 identified by match to protein family HMM PF03264; match to protein family HMM TIGR02162 YP_002269723.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164 YP_002269724.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_002269725.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_002269726.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_002269727.1 identified by glimmer YP_002269728.1 identified by match to protein family HMM PF00328 YP_002269730.1 stationary phase that binds TrpR repressor YP_002269731.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03616 YP_002269732.1 identified by match to protein family HMM PF01613; match to protein family HMM TIGR03615 YP_002269733.1 identified by match to protein family HMM PF00881 YP_002269734.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR03611 YP_002269735.1 identified by match to protein family HMM PF00857; match to protein family HMM TIGR03614 YP_002269736.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03612 YP_002269737.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08362; match to protein family HMM TIGR03613 YP_002269738.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_002269739.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002269740.1 identified by glimmer YP_002269743.1 identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145 YP_002269744.1 identified by match to protein family HMM PF09375 YP_002269745.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413 YP_002269746.1 identified by glimmer YP_002269747.1 identified by match to protein family HMM PF02562 YP_002269748.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export YP_002269749.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_002269750.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_002269751.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia YP_002269752.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002269753.1 identified by match to protein family HMM PF00563 YP_002269755.1 identified by match to protein family HMM PF00486 YP_002269756.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370 YP_002269757.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002269759.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002269760.1 identified by match to protein family HMM PF00419 YP_002269762.1 identified by glimmer YP_002269763.1 identified by glimmer YP_002269764.1 identified by match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01731; match to protein family HMM TIGR01901 YP_002269765.1 identified by match to protein family HMM PF03865; match to protein family HMM PF08479 YP_002269766.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00516; match to protein family HMM TIGR00556 YP_002269767.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08659 YP_002269768.1 identified by match to protein family HMM PF07977 YP_002269770.1 identified by match to protein family HMM PF01571; match to protein family HMM PF08669 YP_002269771.1 identified by match to protein family HMM PF00109; match to protein family HMM PF02801 YP_002269772.1 identified by match to protein family HMM PF00109; match to protein family HMM PF02801 YP_002269774.1 identified by match to protein family HMM PF00005 YP_002269776.1 identified by match to protein family HMM PF02687 YP_002269779.1 identified by match to protein family HMM PF00698 YP_002269781.1 identified by match to protein family HMM PF00589 YP_002269782.1 identified by glimmer YP_002269783.1 identified by glimmer YP_002269785.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002269786.1 overlaps another CDS with the same product name YP_002269788.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01896; match to protein family HMM PF04851 YP_002269790.1 identified by match to protein family HMM PF03050 YP_002269791.1 identified by match to protein family HMM PF05717 YP_002269794.1 identified by match to protein family HMM PF00665 YP_002269795.1 identified by match to protein family HMM PF05818 YP_002269796.1 identified by glimmer YP_002269797.1 identified by match to protein family HMM PF01219 YP_002269798.1 identified by match to protein family HMM PF00884; match to protein family HMM PF08019 YP_002269799.1 identified by glimmer YP_002269800.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_002269801.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_002269802.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_002269803.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_002269804.1 identified by match to protein family HMM PF01730 YP_002269805.1 identified by match to protein family HMM PF02492; match to protein family HMM TIGR00101 YP_002269807.1 identified by match to protein family HMM PF01527 YP_002269809.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002269811.1 identified by glimmer YP_002269813.1 identified by glimmer YP_002269816.1 identified by match to protein family HMM PF01527 YP_002269817.1 identified by match to protein family HMM PF05717 YP_002269818.1 identified by match to protein family HMM PF03050 YP_002269819.1 identified by match to protein family HMM PF03050 YP_002269827.1 identified by match to protein family HMM PF02655 YP_002269828.1 identified by match to protein family HMM PF02342 YP_002269829.1 identified by match to protein family HMM PF02342 YP_002269830.1 identified by match to protein family HMM PF05099 YP_002269831.1 identified by match to protein family HMM PF03741 YP_002269832.1 identified by match to protein family HMM PF02342 YP_002269833.1 identified by match to protein family HMM PF02342 YP_002269835.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor YP_002269836.1 identified by glimmer YP_002269837.1 identified by glimmer YP_002269838.1 identified by glimmer YP_002269841.1 identified by glimmer YP_002269842.1 identified by match to protein family HMM PF06722 YP_002269844.1 identified by match to protein family HMM PF03400 YP_002269846.1 identified by glimmer YP_002269851.1 identified by glimmer YP_002269852.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002269853.1 overlaps another CDS with the same product name YP_002269854.1 identified by match to protein family HMM PF08479; match to protein family HMM TIGR01731 YP_002269855.1 identified by glimmer YP_002269856.1 identified by match to protein family HMM PF01507 YP_002269857.1 identified by match to protein family HMM PF02195 YP_002269858.1 identified by match to protein family HMM PF06069 YP_002269861.1 identified by match to protein family HMM PF01527 YP_002269863.1 identified by match to protein family HMM PF01926 YP_002269864.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002269867.1 identified by match to protein family HMM PF01734 YP_002269869.1 identified by match to protein family HMM PF06067 YP_002269870.1 identified by match to protein family HMM PF03230 YP_002269871.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_002269872.1 identified by match to protein family HMM PF06174 YP_002269874.1 identified by match to protein family HMM PF06154 YP_002269875.1 identified by match to protein family HMM PF06755 YP_002269877.1 identified by match to protein family HMM PF06117 YP_002269879.1 identified by match to protein family HMM PF02826 YP_002269880.1 identified by match to protein family HMM PF02811 YP_002269881.1 identified by match to protein family HMM PF06192 YP_002269882.1 identified by glimmer YP_002269883.1 identified by match to protein family HMM PF06496 YP_002269884.1 identified by match to protein family HMM PF03783 YP_002269885.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_002269886.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_002269887.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_002269888.1 identified by glimmer YP_002269889.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_002269890.1 identified by match to protein family HMM PF07012 YP_002269891.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_002269893.1 identified by match to protein family HMM PF01661 YP_002269894.1 identified by match to protein family HMM PF00614 YP_002269895.1 required for the transfer of succinyl residues to the glucan backbone YP_002269896.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_002269897.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_002269898.1 identified by match to protein family HMM PF07119 YP_002269900.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002269901.1 identified by match to protein family HMM PF00581 YP_002269902.1 identified by match to protein family HMM PF04264 YP_002269903.1 identified by match to protein family HMM PF01292 YP_002269905.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_002269906.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_002269907.1 identified by match to protein family HMM PF06183 YP_002269908.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002269909.1 identified by match to protein family HMM PF07273 YP_002269910.1 cofactor involved in the reduction of disulfides YP_002269911.1 Confers resistance to norfloxacin and enoxacin YP_002269912.1 identified by match to protein family HMM PF00583 YP_002269913.1 identified by match to protein family HMM PF04337 YP_002269914.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002269915.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_002269916.1 identified by match to protein family HMM PF05130 YP_002269917.1 regulates the flagellar specific sigma28 transcription factor YP_002269918.1 required for the assembly of the flagellar basal body P-ring YP_002269919.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_002269920.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002269921.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_002269922.1 the hook connects flagellar basal body to the flagellar filament YP_002269923.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_002269924.1 makes up the distal portion of the flagellar basal body rod YP_002269925.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_002269926.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_002269927.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002269928.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002269929.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_002269930.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_002269931.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_002269932.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002269933.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002269934.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002269935.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002269936.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002269937.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002269938.1 carries the fatty acid chain in fatty acid biosynthesis YP_002269939.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002269940.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002269941.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002269942.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002269943.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002269944.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002269945.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002269946.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_002269948.1 identified by match to protein family HMM PF01230 YP_002269949.1 identified by match to protein family HMM PF07233 YP_002269950.1 identified by match to protein family HMM TIGR02722 YP_002269951.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_002269952.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002269953.1 identified by match to protein family HMM PF05728 YP_002269954.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_002269955.1 identified by match to protein family HMM PF05433 YP_002269956.1 identified by match to protein family HMM PF00440 YP_002269957.1 identified by match to protein family HMM PF07338 YP_002269958.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_002269959.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002269960.1 identified by match to protein family HMM PF01757 YP_002269961.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002269962.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_002269963.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002269964.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_002269965.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002269966.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_002269967.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_002269968.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002269972.1 identified by match to protein family HMM PF07151 YP_002269974.1 identified by match to protein family HMM PF06254 YP_002269977.1 identified by match to protein family HMM PF07789 YP_002269984.1 identified by match to protein family HMM PF04448 YP_002269986.1 identified by match to protein family HMM PF06914 YP_002269987.1 identified by match to protein family HMM PF05866 YP_002269988.1 identified by match to protein family HMM PF03629 YP_002269989.1 identified by match to protein family HMM PF07125 YP_002269990.1 identified by match to protein family HMM PF05696 YP_002269991.1 identified by match to protein family HMM PF04971 YP_002269992.1 identified by match to protein family HMM PF07041 YP_002269993.1 identified by match to protein family HMM PF00959 YP_002269996.1 identified by match to protein family HMM PF03245 YP_002269998.1 identified by glimmer YP_002270002.1 identified by match to protein family HMM PF03354 YP_002270003.1 identified by match to protein family HMM PF04586 YP_002270004.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002270006.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563 YP_002270007.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725 YP_002270008.1 identified by glimmer YP_002270009.1 identified by match to protein family HMM PF06222 YP_002270010.1 identified by glimmer YP_002270011.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675 YP_002270012.1 identified by match to protein family HMM PF05939 YP_002270013.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002270016.1 identified by match to protein family HMM PF02498 YP_002270017.1 identified by match to protein family HMM PF00877 YP_002270019.1 identified by glimmer YP_002270020.1 identified by glimmer YP_002270022.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats YP_002270025.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_002270026.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_002270027.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002270028.1 identified by match to protein family HMM PF08007 YP_002270030.1 identified by match to protein family HMM PF00589 YP_002270032.1 identified by glimmer YP_002270037.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_002270038.1 identified by glimmer YP_002270040.1 identified by match to protein family HMM PF03864 YP_002270041.1 identified by match to protein family HMM PF02924 YP_002270043.1 identified by match to protein family HMM PF07471 YP_002270046.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918 YP_002270047.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_002270048.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002270049.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002270050.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002270051.1 identified by match to protein family HMM PF00293 YP_002270052.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA YP_002270054.1 Converts isocitrate to alpha ketoglutarate YP_002270055.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002270056.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002270057.1 identified by match to protein family HMM PF06992 YP_002270059.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation YP_002270060.1 DLP12 prophage YP_002270061.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins YP_002270062.1 identified by match to protein family HMM PF07102 YP_002270063.1 DLP12 prophage; Holliday junction resolvase YP_002270065.1 identified by match to protein family HMM PF06323 YP_002270067.1 identified by match to protein family HMM PF00959 YP_002270068.1 identified by match to protein family HMM PF03245 YP_002270069.1 identified by match to protein family HMM PF06291 YP_002270070.1 identified by match to protein family HMM PF07166 YP_002270073.1 identified by match to protein family HMM PF07471 YP_002270074.1 identified by match to protein family HMM PF05876 YP_002270075.1 identified by match to protein family HMM PF02831 YP_002270076.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002270077.1 identified by match to protein family HMM PF01343 YP_002270078.1 identified by match to protein family HMM PF02924 YP_002270079.1 identified by match to protein family HMM PF03864 YP_002270081.1 identified by match to protein family HMM PF05354 YP_002270082.1 identified by match to protein family HMM PF06763 YP_002270083.1 identified by match to protein family HMM PF06141 YP_002270084.1 identified by match to protein family HMM PF02368 YP_002270085.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002270086.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002270087.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002270088.1 identified by match to protein family HMM PF05939 YP_002270089.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002270090.1 identified by match to protein family HMM PF00877 YP_002270091.1 identified by match to protein family HMM PF06805 YP_002270092.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002270093.1 identified by match to protein family HMM PF06316 YP_002270096.1 identified by glimmer YP_002270097.1 identified by match to protein family HMM PF03335; match to protein family HMM PF03406; match to protein family HMM PF07484 YP_002270098.1 identified by match to protein family HMM PF02413 YP_002270099.1 identified by match to protein family HMM PF05067 YP_002270100.1 identified by match to protein family HMM PF05974 YP_002270101.1 identified by match to protein family HMM PF05974 YP_002270104.1 identified by match to protein family HMM PF05717 YP_002270105.1 identified by match to protein family HMM PF03050 YP_002270106.1 identified by match to protein family HMM PF00561; match to protein family HMM PF08386 YP_002270107.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_002270108.1 identified by glimmer YP_002270109.1 identified by match to protein family HMM PF01381 YP_002270110.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002270111.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002270112.1 identified by glimmer YP_002270113.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002270114.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_002270115.1 blocks the formation of polar Z-ring septums YP_002270116.1 identified by match to protein family HMM PF05666 YP_002270117.1 identified by match to protein family HMM PF04151 YP_002270120.1 identified by match to protein family HMM PF01557 YP_002270121.1 identified by match to protein family HMM PF03692 YP_002270122.1 Acts by forming a pore-like structure upon contact with mammalian cells YP_002270123.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002270124.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002270125.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002270126.1 involved in regulation of intracellular pH under alkaline conditions YP_002270127.1 Multifunctional regulator of fatty acid metabolism YP_002270128.1 identified by match to protein family HMM PF04293 YP_002270129.1 catalyzes the oxidative deamination of D-amino acids YP_002270130.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_002270131.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_002270132.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_002270133.1 identified by match to protein family HMM PF01464 YP_002270136.1 identified by glimmer YP_002270137.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002270138.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002270139.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_002270140.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_002270141.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002270142.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002270143.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002270144.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002270145.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002270146.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_002270147.1 identified by match to protein family HMM PF04247 YP_002270149.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002270150.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846 YP_002270151.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_002270152.1 identified by match to protein family HMM PF04752 YP_002270153.1 identified by match to protein family HMM PF02635 YP_002270155.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_002270156.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002270157.1 identified by glimmer YP_002270158.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_002270159.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002270160.1 identified by match to protein family HMM TIGR01660 YP_002270161.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002270162.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002270163.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002270164.1 identified by match to protein family HMM PF02810 YP_002270165.1 identified by match to protein family HMM PF01734 YP_002270166.1 identified by match to protein family HMM PF00072 YP_002270167.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002270168.1 identified by match to protein family HMM PF00816 YP_002270169.1 identified by glimmer YP_002270170.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002270171.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465 YP_002270172.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427 YP_002270173.1 identified by glimmer YP_002270174.1 identified by match to protein family HMM PF00496 YP_002270175.1 identified by match to protein family HMM PF00528 YP_002270176.1 identified by match to protein family HMM PF00528 YP_002270177.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002270178.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002270179.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_002270180.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002270182.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885 YP_002270183.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_002270184.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_002270185.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_002270186.1 Involved in cell division; probably involved in intracellular septation YP_002270187.1 receptor for colicin S4 YP_002270188.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002270189.1 identified by match to protein family HMM PF00929 YP_002270190.1 identified by match to protein family HMM PF07358 YP_002270191.1 identified by match to protein family HMM PF05358 YP_002270192.1 identified by glimmer YP_002270195.1 identified by glimmer YP_002270197.1 identified by glimmer YP_002270204.1 identified by glimmer YP_002270205.1 identified by match to protein family HMM PF06914 YP_002270206.1 identified by match to protein family HMM PF05866 YP_002270207.1 identified by match to protein family HMM PF06576 YP_002270209.1 identified by match to protein family HMM PF01555 YP_002270210.1 identified by match to protein family HMM PF04971 YP_002270211.1 identified by match to protein family HMM PF07041 YP_002270212.1 identified by match to protein family HMM PF00959 YP_002270215.1 identified by match to protein family HMM PF03245 YP_002270217.1 identified by glimmer YP_002270219.1 identified by match to protein family HMM PF07471 YP_002270220.1 identified by match to protein family HMM PF05876 YP_002270221.1 identified by match to protein family HMM PF02831 YP_002270222.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002270223.1 identified by match to protein family HMM PF01343 YP_002270224.1 identified by match to protein family HMM PF02924 YP_002270225.1 identified by match to protein family HMM PF03864 YP_002270227.1 identified by match to protein family HMM PF05354 YP_002270228.1 identified by match to protein family HMM PF06763 YP_002270229.1 identified by match to protein family HMM PF06141 YP_002270230.1 identified by match to protein family HMM PF02368 YP_002270231.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002270232.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002270233.1 identified by match to protein family HMM PF05939 YP_002270234.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002270235.1 identified by match to protein family HMM PF06805 YP_002270236.1 identified by glimmer YP_002270237.1 identified by match to protein family HMM PF09327 YP_002270238.1 identified by match to protein family HMM PF06316 YP_002270239.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002270240.1 identified by match to protein family HMM PF06820 YP_002270241.1 identified by glimmer YP_002270244.1 identified by match to protein family HMM PF03050 YP_002270245.1 identified by match to protein family HMM PF05717 YP_002270246.1 identified by match to protein family HMM PF06416 YP_002270247.1 identified by match to protein family HMM PF03278 YP_002270249.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002270250.1 identified by match to protein family HMM PF06630 YP_002270251.1 identified by match to protein family HMM PF07358 YP_002270253.1 identified by glimmer YP_002270254.1 identified by glimmer YP_002270255.1 identified by match to protein family HMM PF07151 YP_002270257.1 identified by glimmer YP_002270259.1 identified by match to protein family HMM PF06254 YP_002270262.1 identified by match to protein family HMM PF07789 YP_002270263.1 identified by match to protein family HMM PF06163 YP_002270267.1 identified by match to protein family HMM PF04448 YP_002270270.1 identified by match to protein family HMM PF06914 YP_002270271.1 identified by match to protein family HMM PF05866 YP_002270272.1 identified by match to protein family HMM PF03589 YP_002270274.1 identified by match to protein family HMM PF01555 YP_002270275.1 identified by glimmer YP_002270277.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002270279.1 identified by match to protein family HMM PF07125 YP_002270280.1 identified by match to protein family HMM PF05696 YP_002270281.1 identified by match to protein family HMM PF04971 YP_002270283.1 identified by match to protein family HMM PF00959 YP_002270284.1 identified by match to protein family HMM PF03245 YP_002270285.1 identified by match to protein family HMM PF07278 YP_002270286.1 identified by match to protein family HMM PF05876 YP_002270288.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002270289.1 identified by match to protein family HMM PF00574 YP_002270292.1 identified by match to protein family HMM PF06763 YP_002270293.1 identified by match to protein family HMM PF06141 YP_002270294.1 identified by match to protein family HMM PF02368 YP_002270295.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002270296.1 identified by match to protein family HMM TIGR01715 YP_002270297.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002270298.1 identified by match to protein family HMM PF05939 YP_002270299.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002270300.1 identified by match to protein family HMM PF00877 YP_002270301.1 identified by match to protein family HMM PF06805 YP_002270302.1 identified by glimmer YP_002270303.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002270304.1 identified by match to protein family HMM PF06316 YP_002270306.1 identified by match to protein family HMM PF06820 YP_002270308.1 identified by match to protein family HMM PF03400 YP_002270311.1 identified by match to protein family HMM PF05974 YP_002270312.1 identified by match to protein family HMM PF05974 YP_002270314.1 identified by glimmer YP_002270315.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002270316.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002270317.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002270318.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_002270319.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002270320.1 identified by match to protein family HMM PF02811 YP_002270321.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_002270323.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_002270324.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_002270325.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002270326.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002270328.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002270329.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_002270332.1 Catalyzes the conversion of citrate to isocitrate YP_002270333.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_002270334.1 identified by match to protein family HMM PF01569 YP_002270335.1 identified by match to protein family HMM PF06305 YP_002270336.1 identified by match to protein family HMM PF07719 YP_002270337.1 identified by glimmer YP_002270338.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002270339.1 involved in start site selection during the initiation of translation YP_002270341.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002270343.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002270345.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002270346.1 identified by match to protein family HMM PF00440 YP_002270347.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002270348.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845 YP_002270349.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_002270350.1 identified by match to protein family HMM PF00005 YP_002270351.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002270352.1 identified by match to protein family HMM PF00528 YP_002270353.1 identified by match to protein family HMM PF00528 YP_002270354.1 identified by match to protein family HMM PF00496 YP_002270355.1 identified by glimmer YP_002270357.1 identified by match to protein family HMM PF00324 YP_002270358.1 identified by match to protein family HMM PF00120 YP_002270359.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_002270360.1 regulates genes involved in putrescine degradation YP_002270361.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_002270362.1 identified by match to protein family HMM PF01266 YP_002270363.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate YP_002270364.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_002270365.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_002270366.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_002270367.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_002270368.1 identified by match to protein family HMM PF09584; match to protein family HMM TIGR02979 YP_002270369.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_002270370.1 identified by glimmer YP_002270371.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528 YP_002270372.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528 YP_002270373.1 identified by match to protein family HMM PF00107 YP_002270374.1 identified by match to protein family HMM PF01261 YP_002270375.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002270376.1 identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636 YP_002270377.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009 YP_002270378.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002270379.1 identified by match to protein family HMM PF09381 YP_002270380.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002270381.1 identified by match to protein family HMM PF04317 YP_002270382.1 identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620 YP_002270383.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_002270384.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002270385.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002270386.1 identified by match to protein family HMM PF00246 YP_002270388.1 identified by match to protein family HMM PF02129 YP_002270389.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270390.1 identified by match to protein family HMM PF00496 YP_002270391.1 identified by match to protein family HMM PF00924 YP_002270393.1 with UspC and UspD is involved in resistance to UV irradiation YP_002270394.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002270395.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002270396.1 identified by match to protein family HMM PF03806; match to protein family HMM TIGR00819 YP_002270397.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002270398.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002270399.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270400.1 identified by match to protein family HMM PF01713 YP_002270401.1 identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002270402.1 identified by match to protein family HMM PF01544 YP_002270403.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_002270404.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002270405.1 identified by match to protein family HMM PF00582 YP_002270406.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176 YP_002270407.1 identified by glimmer YP_002270409.1 identified by match to protein family HMM PF03724 YP_002270410.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002270411.1 identified by glimmer YP_002270413.1 identified by match to protein family HMM PF07027 YP_002270414.1 identified by match to protein family HMM PF00248 YP_002270415.1 identified by glimmer YP_002270416.1 identified by glimmer YP_002270417.1 identified by match to protein family HMM PF01066 YP_002270418.1 identified by match to protein family HMM PF01148 YP_002270420.1 identified by match to protein family HMM PF00782; match to protein family HMM PF01569 YP_002270421.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002270422.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_002270426.1 identified by match to protein family HMM PF02698 YP_002270427.1 NAD-linked YP_002270428.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002270429.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_002270431.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002270432.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270433.1 identified by match to protein family HMM PF07063 YP_002270434.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_002270435.1 identified by match to protein family HMM PF04325 YP_002270437.1 identified by match to protein family HMM PF03595; match to protein family HMM TIGR00816 YP_002270438.1 with TehA confers resistance to tellurite YP_002270440.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002270441.1 identified by match to protein family HMM PF01136 YP_002270443.1 identified by glimmer YP_002270444.1 identified by match to protein family HMM PF01381; match to protein family HMM PF03681 YP_002270445.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002270446.1 identified by match to protein family HMM PF01547 YP_002270447.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_002270448.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528 YP_002270449.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528 YP_002270450.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_002270451.1 identified by glimmer YP_002270454.1 identified by match to protein family HMM PF04657 YP_002270455.1 identified by match to protein family HMM PF00583 YP_002270456.1 identified by match to protein family HMM PF00107 YP_002270457.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002270458.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_002270460.1 identified by match to protein family HMM PF00324 YP_002270461.1 identified by glimmer YP_002270464.1 identified by glimmer YP_002270465.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_002270466.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002270467.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002270468.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002270469.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002270470.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002270471.1 identified by match to protein family HMM TIGR01660 YP_002270472.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002270473.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_002270475.1 identified by match to protein family HMM PF00267 YP_002270476.1 identified by match to protein family HMM PF00892 YP_002270477.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_002270478.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_002270479.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_002270480.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002270481.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002270482.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_002270484.1 identified by match to protein family HMM PF02566; match to protein family HMM TIGR03562 YP_002270485.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002270486.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002270487.1 identified by match to protein family HMM PF00528 YP_002270488.1 identified by match to protein family HMM PF00528 YP_002270489.1 identified by match to protein family HMM PF00496 YP_002270490.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_002270491.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002270492.1 identified by match to protein family HMM PF02638 YP_002270493.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910 YP_002270494.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_002270495.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002270496.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_002270497.1 identified by match to protein family HMM PF00005; match to protein family HMM PF05992; match to protein family HMM PF06472 YP_002270498.1 identified by match to protein family HMM PF04055 YP_002270499.1 regulates the cellular response to acid resistance YP_002270501.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family YP_002270502.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160 YP_002270504.1 identified by match to protein family HMM PF00419 YP_002270505.1 identified by match to protein family HMM PF00577 YP_002270506.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002270507.1 identified by match to protein family HMM PF00419 YP_002270508.1 identified by match to protein family HMM PF07804; match to protein family HMM PF07805 YP_002270509.1 identified by glimmer YP_002270510.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002270511.1 identified by match to protein family HMM PF04198 YP_002270512.1 identified by match to protein family HMM PF00005 YP_002270513.1 identified by match to protein family HMM PF02653 YP_002270514.1 identified by match to protein family HMM PF02653 YP_002270516.1 identified by match to protein family HMM PF01791 YP_002270517.1 identified by match to protein family HMM PF03992 YP_002270518.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_002270519.1 identified by match to protein family HMM PF05249 YP_002270520.1 catalyzes the formation of D-tagaturonate from D-altronate YP_002270521.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002270523.1 catalyzes the formation of glutamate from glutamine YP_002270524.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_002270525.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270526.1 identified by match to protein family HMM PF07690 YP_002270527.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_002270528.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_002270529.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF YP_002270531.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_002270532.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_002270534.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_002270535.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002270536.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_002270537.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_002270538.1 identified by match to protein family HMM PF01432 YP_002270539.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_002270540.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002270541.1 identified by match to protein family HMM TIGR03318 YP_002270542.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002270543.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002270544.1 identified by match to protein family HMM PF06183 YP_002270545.1 identified by match to protein family HMM PF06416 YP_002270546.1 identified by match to protein family HMM PF06416 YP_002270547.1 identified by match to protein family HMM PF06416 YP_002270548.1 identified by match to protein family HMM PF06820 YP_002270549.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002270550.1 identified by match to protein family HMM PF06316 YP_002270551.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002270553.1 identified by match to protein family HMM PF06805 YP_002270554.1 identified by match to protein family HMM PF00877 YP_002270555.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002270556.1 identified by match to protein family HMM PF05939 YP_002270557.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675 YP_002270558.1 identified by glimmer YP_002270559.1 identified by match to protein family HMM PF06222 YP_002270560.1 identified by match to protein family HMM PF07679 YP_002270561.1 identified by glimmer YP_002270562.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725 YP_002270563.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563 YP_002270567.1 identified by match to protein family HMM PF07041 YP_002270568.1 identified by match to protein family HMM PF04971 YP_002270570.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002270573.1 identified by match to protein family HMM PF00165 YP_002270574.1 identified by glimmer YP_002270576.1 identified by match to protein family HMM PF06576 YP_002270577.1 identified by match to protein family HMM PF06914 YP_002270579.1 identified by match to protein family HMM PF01336; match to protein family HMM PF04076 YP_002270580.1 identified by match to protein family HMM PF04448 YP_002270585.1 identified by match to protein family HMM PF07789 YP_002270588.1 identified by match to protein family HMM PF06254 YP_002270589.1 identified by match to protein family HMM PF00717 YP_002270590.1 identified by match to protein family HMM PF07151 YP_002270591.1 identified by glimmer YP_002270592.1 identified by glimmer YP_002270593.1 identified by glimmer YP_002270595.1 identified by match to protein family HMM PF07358 YP_002270596.1 identified by match to protein family HMM PF06183 YP_002270597.1 identified by match to protein family HMM PF00872 YP_002270598.1 identified by match to protein family HMM PF05717 YP_002270599.1 identified by match to protein family HMM PF03050 YP_002270601.1 identified by match to protein family HMM PF06416 YP_002270603.1 identified by match to protein family HMM PF06416 YP_002270604.1 identified by match to protein family HMM PF06820 YP_002270605.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002270606.1 identified by match to protein family HMM PF06316 YP_002270607.1 identified by glimmer YP_002270608.1 identified by match to protein family HMM TIGR01600 YP_002270609.1 identified by match to protein family HMM PF05939 YP_002270610.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675 YP_002270611.1 identified by glimmer YP_002270612.1 identified by match to protein family HMM PF06222 YP_002270613.1 identified by glimmer YP_002270614.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725 YP_002270615.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563 YP_002270617.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002270618.1 identified by match to protein family HMM PF04586 YP_002270619.1 identified by match to protein family HMM PF03354 YP_002270621.1 identified by match to protein family HMM PF01844 YP_002270623.1 identified by match to protein family HMM PF03245 YP_002270626.1 identified by match to protein family HMM PF00959 YP_002270627.1 identified by match to protein family HMM PF07041 YP_002270628.1 identified by match to protein family HMM PF04971 YP_002270629.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002270631.1 identified by glimmer YP_002270632.1 identified by match to protein family HMM PF06323 YP_002270633.1 identified by match to protein family HMM PF05866 YP_002270634.1 identified by match to protein family HMM PF06914 YP_002270636.1 identified by match to protein family HMM PF04448 YP_002270637.1 identified by match to protein family HMM PF06163 YP_002270638.1 identified by match to protein family HMM PF01695 YP_002270640.1 identified by match to protein family HMM PF06254 YP_002270643.1 identified by glimmer YP_002270645.1 identified by match to protein family HMM PF05358 YP_002270646.1 identified by match to protein family HMM PF07358 YP_002270648.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002270649.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002270650.1 identified by match to protein family HMM PF00929 YP_002270651.1 identified by match to protein family HMM PF06806 YP_002270653.1 identified by match to protein family HMM PF02694 YP_002270654.1 identified by match to protein family HMM PF06932 YP_002270655.1 identified by match to protein family HMM PF00583 YP_002270656.1 identified by match to protein family HMM PF06788 YP_002270657.1 identified by match to protein family HMM PF06649 YP_002270658.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002270659.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002270660.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002270661.1 identified by match to protein family HMM PF04976 YP_002270662.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_002270663.1 identified by glimmer YP_002270664.1 identified by match to protein family HMM PF00654 YP_002270665.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002270666.1 identified by match to protein family HMM PF00480 YP_002270667.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270668.1 identified by match to protein family HMM PF07690 YP_002270669.1 required for growth and survival under moderately acid conditions YP_002270670.1 identified by match to protein family HMM PF00089 YP_002270671.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_002270672.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_002270673.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_002270674.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_002270675.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_002270676.1 identified by match to protein family HMM PF07338 YP_002270677.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002270678.1 identified by match to protein family HMM PF00106 YP_002270679.1 identified by match to protein family HMM PF06942 YP_002270680.1 response regulator in two-component regulatory system with RstB YP_002270681.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002270682.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_002270683.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002270684.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002270685.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_002270686.1 identified by match to protein family HMM PF06097 YP_002270687.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_002270688.1 identified by match to protein family HMM PF00440 YP_002270689.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_002270690.1 regulates malXY which are involved in maltose-glucose transport YP_002270691.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_002270692.1 identified by match to protein family HMM PF00155 YP_002270693.1 catalyzes the formation of inosine from adenosine YP_002270694.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002270695.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_002270697.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943 YP_002270698.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002270699.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002270700.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_002270701.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002270702.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_002270703.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_002270704.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_002270705.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002270706.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002270707.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002270708.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002270709.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_002270710.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002270711.1 identified by match to protein family HMM PF05433 YP_002270712.1 Transcription regulator that can both activate or repress expression YP_002270713.1 identified by match to protein family HMM PF07869 YP_002270714.1 identified by match to protein family HMM PF00529 YP_002270715.1 identified by match to protein family HMM PF04632 YP_002270716.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_002270717.1 identified by glimmer YP_002270718.1 identified by match to protein family HMM PF00440 YP_002270719.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_002270720.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_002270721.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002270722.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli YP_002270723.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365 YP_002270724.1 identified by match to protein family HMM PF00877 YP_002270725.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_002270726.1 identified by match to protein family HMM PF07690 YP_002270727.1 identified by glimmer YP_002270728.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_002270729.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270730.1 uncharacterized member of the major facilitator superfamily (MFS) YP_002270731.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_002270732.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002270733.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002270735.1 identified by match to protein family HMM PF08803 YP_002270738.1 identified by match to protein family HMM PF01292 YP_002270739.1 identified by match to protein family HMM PF00037 YP_002270741.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730 YP_002270742.1 identified by match to protein family HMM PF00037 YP_002270743.1 identified by glimmer YP_002270745.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002270746.1 identified by match to protein family HMM PF04728 YP_002270747.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_002270748.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_002270749.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_002270750.1 with SufBC activates cysteine desulfurase SufS YP_002270751.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_002270752.1 with SufCD activates cysteine desulfurase SufS YP_002270753.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_002270755.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002270756.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_002270757.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_002270758.1 identified by match to protein family HMM PF08965 YP_002270759.1 identified by match to protein family HMM PF07690 YP_002270760.1 identified by match to protein family HMM PF07690 YP_002270761.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_002270762.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_002270763.1 identified by match to protein family HMM PF01144 YP_002270764.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002270765.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883 YP_002270766.1 identified by glimmer YP_002270767.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002270768.1 May play a role in a redox process YP_002270769.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486 YP_002270771.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002270772.1 identified by glimmer YP_002270773.1 identified by match to protein family HMM PF03618 YP_002270774.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_002270776.1 identified by match to protein family HMM PF02696 YP_002270778.1 identified by match to protein family HMM PF00877 YP_002270779.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_002270780.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_002270781.1 with BtuD and BtuF transports vitamin B12 into the cell YP_002270782.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002270783.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002270784.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002270786.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002270787.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002270788.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002270789.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002270790.1 identified by match to protein family HMM PF07906 YP_002270792.1 identified by match to protein family HMM PF04338 YP_002270793.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002270795.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881 YP_002270797.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_002270798.1 identified by match to protein family HMM PF04307 YP_002270799.1 identified by match to protein family HMM PF00375 YP_002270801.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_002270802.1 identified by match to protein family HMM PF04794 YP_002270803.1 identified by match to protein family HMM PF02056 YP_002270804.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_002270805.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002270806.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002270807.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002270808.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_002270809.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002270810.1 3' incision activity; acts with UvrC YP_002270811.1 identified by match to protein family HMM PF05962 YP_002270812.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_002270813.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002270814.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002270815.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_002270816.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03243; match to protein family HMM TIGR03244 YP_002270817.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_002270818.1 identified by glimmer YP_002270819.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_002270820.1 identified by match to protein family HMM PF09335 YP_002270822.1 identified by match to protein family HMM PF09335 YP_002270823.1 identified by match to protein family HMM PF02627 YP_002270824.1 identified by match to protein family HMM PF01547 YP_002270826.1 identified by match to protein family HMM PF00005 YP_002270827.1 identified by match to protein family HMM PF00581 YP_002270828.1 identified by match to protein family HMM PF01066 YP_002270829.1 identified by match to protein family HMM PF00293 YP_002270830.1 identified by match to protein family HMM PF07383 YP_002270831.1 identified by glimmer YP_002270832.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002270834.1 decatenates replicating daughter chromosomes YP_002270835.1 catalyzes the formation of selenophosphate from selenide and ATP YP_002270836.1 identified by match to protein family HMM PF00881 YP_002270837.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_002270838.1 identified by match to protein family HMM PF04402 YP_002270839.1 converts asparagine to aspartate and ammonia YP_002270840.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_002270841.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002270842.1 overlaps another CDS with the same product name YP_002270843.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002270844.1 identified by glimmer YP_002270845.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002270846.1 identified by match to protein family HMM PF00248 YP_002270847.1 identified by match to protein family HMM PF00294 YP_002270848.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167 YP_002270849.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002270850.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002270851.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002270852.1 identified by match to protein family HMM PF07023 YP_002270853.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_002270854.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002270855.1 identified by match to protein family HMM PF01263 YP_002270856.1 identified by match to protein family HMM PF00248 YP_002270857.1 identified by match to protein family HMM PF06629 YP_002270858.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_002270859.1 identified by match to protein family HMM PF04285 YP_002270860.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002270861.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002270862.1 identified by match to protein family HMM PF04073 YP_002270864.1 identified by match to protein family HMM PF04284 YP_002270865.1 identified by match to protein family HMM PF00165 YP_002270866.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00896 YP_002270867.1 identified by match to protein family HMM PF04343 YP_002270868.1 identified by match to protein family HMM PF03891 YP_002270869.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254 YP_002270871.1 identified by match to protein family HMM PF04226 YP_002270872.1 identified by match to protein family HMM PF08956 YP_002270873.1 identified by match to protein family HMM PF09313 YP_002270874.1 identified by glimmer YP_002270875.1 identified by match to protein family HMM PF01810 YP_002270876.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002270877.1 identified by match to protein family HMM PF00180; match to protein family HMM TIGR02089 YP_002270878.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_002270879.1 identified by match to protein family HMM PF00355 YP_002270880.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002270881.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388 YP_002270882.1 Activates fatty acids by binding to coenzyme A YP_002270883.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_002270884.1 identified by match to protein family HMM PF00814 YP_002270886.1 identified by match to protein family HMM PF01042 YP_002270887.1 identified by glimmer YP_002270888.1 identified by glimmer YP_002270889.1 identified by match to protein family HMM PF08986 YP_002270890.1 identified by match to protein family HMM PF03701 YP_002270891.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553 YP_002270892.1 identified by match to protein family HMM PF00293 YP_002270893.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002270894.1 identified by match to protein family HMM PF00563 YP_002270895.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_002270896.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854 YP_002270897.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_002270898.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_002270899.1 identified by match to protein family HMM PF06173 YP_002270900.1 identified by glimmer YP_002270901.1 membrane protein YebN YP_002270902.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_002270903.1 identified by match to protein family HMM PF00313 YP_002270908.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002270909.1 identified by match to protein family HMM PF07690 YP_002270910.1 metalloprotease YP_002270911.1 identified by glimmer YP_002270912.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002270913.1 affects solute and DNA transport through an unknown mechanism YP_002270914.1 identified by match to protein family HMM PF01590 YP_002270915.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_002270916.1 identified by match to protein family HMM PF02470 YP_002270917.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002270918.1 identified by match to protein family HMM PF07351 YP_002270919.1 identified by match to protein family HMM PF07358 YP_002270920.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_002270922.1 identified by match to protein family HMM PF05425 YP_002270923.1 identified by match to protein family HMM PF04234 YP_002270924.1 identified by match to protein family HMM PF06440 YP_002270925.1 identified by match to protein family HMM PF00795 YP_002270926.1 3'-5' exonuclease activity on single or double-strand DNA YP_002270927.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_002270928.1 identified by match to protein family HMM PF04391 YP_002270929.1 secreted protein; unknown function YP_002270930.1 identified by match to protein family HMM PF07130 YP_002270931.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_002270932.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002270933.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002270934.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002270936.1 Represses the expression of the zwf, eda, glp and gap YP_002270937.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002270938.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_002270939.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_002270940.1 involved in transport of zinc(II) with ZnuA and C YP_002270941.1 involved in transport of zinc(II) with ZnuA and C YP_002270942.1 involved in transport of zinc(II) with ZnuA and C YP_002270943.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002270944.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002270945.1 identified by match to protein family HMM PF06520 YP_002270946.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002270947.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002270948.1 converts dATP to dAMP and pyrophosphate YP_002270949.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002270950.1 identified by match to protein family HMM PF00857 YP_002270951.1 identified by match to protein family HMM PF01904 YP_002270953.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740 YP_002270954.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452 YP_002270955.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409 YP_002270956.1 identified by match to protein family HMM PF03264 YP_002270957.1 identified by match to protein family HMM PF03932 YP_002270958.1 identified by match to protein family HMM PF06185 YP_002270960.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002270961.1 identified by match to protein family HMM PF07007 YP_002270962.1 identified by match to protein family HMM PF06366 YP_002270963.1 membrane protein involved in the flagellar export apparatus YP_002270964.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002270965.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_002270966.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_002270967.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002270968.1 methylates the MCP YP_002270969.1 mediates taxis toward dipeptides YP_002270970.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002270971.1 identified by match to protein family HMM PF01584 YP_002270972.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_002270973.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002270974.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002270975.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002270976.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_002270977.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002270978.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400 YP_002270979.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_002270980.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002270981.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002270982.1 identified by match to protein family HMM PF00532 YP_002270983.1 identified by match to protein family HMM PF00210 YP_002270985.1 identified by glimmer YP_002270986.1 identified by glimmer YP_002270988.1 identified by glimmer YP_002270989.1 cytoplasmic iron storage protein YP_002270991.1 identified by glimmer YP_002270992.1 identified by match to protein family HMM PF03222; match to protein family HMM TIGR00837 YP_002270993.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292 YP_002270994.1 identified by match to protein family HMM PF00589 YP_002271002.1 identified by glimmer YP_002271008.1 identified by match to protein family HMM PF05840 YP_002271009.1 identified by match to protein family HMM PF06406 YP_002271010.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271011.1 overlaps another CDS with the same product name YP_002271012.1 identified by match to protein family HMM PF02413 YP_002271013.1 identified by match to protein family HMM PF00132 YP_002271014.1 identified by match to protein family HMM PF06995 YP_002271015.1 identified by match to protein family HMM PF06528 YP_002271016.1 identified by match to protein family HMM PF06158 YP_002271017.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611 YP_002271018.1 identified by match to protein family HMM PF04984 YP_002271019.1 identified by glimmer YP_002271021.1 identified by match to protein family HMM PF00665 YP_002271022.1 overlaps another CDS with the same product name YP_002271023.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271024.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002271025.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002271026.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002271027.1 identified by glimmer YP_002271028.1 identified by glimmer YP_002271030.1 regulates genes involved in cell division YP_002271031.1 identified by match to protein family HMM PF00005 YP_002271032.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002271033.1 catalyzes the formation of pyruvate from D-cysteine YP_002271034.1 identified by match to protein family HMM PF00497 YP_002271035.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_002271036.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002271037.1 identified by glimmer YP_002271038.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes YP_002271039.1 involved in flagellin assembly YP_002271040.1 flagellin specific chaperone YP_002271041.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_002271042.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002271044.1 identified by match to protein family HMM PF04143 YP_002271045.1 identified by match to protein family HMM PF01206 YP_002271046.1 identified by match to protein family HMM PF02586 YP_002271047.1 identified by match to protein family HMM PF00583 YP_002271048.1 identified by glimmer YP_002271049.1 identified by match to protein family HMM PF00583 YP_002271050.1 identified by glimmer YP_002271051.1 identified by glimmer YP_002271052.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_002271054.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_002271055.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002271056.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002271057.1 involved in type III protein export during flagellum assembly YP_002271058.1 rod/hook and filament chaperone YP_002271059.1 identified by match to protein family HMM PF02120 YP_002271060.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002271061.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002271062.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002271063.1 identified by glimmer YP_002271064.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus YP_002271065.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_002271066.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002271067.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_002271068.1 identified by match to protein family HMM PF00196 YP_002271071.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_002271072.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002271073.1 identified by match to protein family HMM PF05661 YP_002271074.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_002271075.1 identified by match to protein family HMM PF03852; match to protein family HMM TIGR00632 YP_002271076.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002271077.1 identified by match to protein family HMM PF01966 YP_002271078.1 identified by glimmer YP_002271079.1 identified by glimmer YP_002271080.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_002271081.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_002271082.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_002271083.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_002271084.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002271085.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002271086.1 identified by match to protein family HMM PF09223 YP_002271087.1 identified by match to protein family HMM PF01292 YP_002271089.1 identified by glimmer YP_002271091.1 identified by match to protein family HMM PF06820 YP_002271092.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820 YP_002271095.1 identified by match to protein family HMM PF06316 YP_002271096.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002271097.1 identified by glimmer YP_002271098.1 identified by match to protein family HMM PF06805 YP_002271099.1 identified by match to protein family HMM PF00877 YP_002271100.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002271101.1 identified by match to protein family HMM PF05939 YP_002271102.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002271103.1 identified by match to protein family HMM TIGR01715 YP_002271104.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002271105.1 identified by match to protein family HMM PF02368 YP_002271107.1 identified by match to protein family HMM PF02924 YP_002271108.1 identified by match to protein family HMM PF01343 YP_002271109.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002271110.1 identified by match to protein family HMM PF02831 YP_002271115.1 identified by match to protein family HMM PF03245 YP_002271117.1 identified by match to protein family HMM PF00959 YP_002271118.1 identified by match to protein family HMM PF07041 YP_002271119.1 identified by match to protein family HMM PF04971 YP_002271120.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002271121.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271122.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002271124.1 identified by glimmer YP_002271125.1 identified by match to protein family HMM PF06323 YP_002271126.1 identified by match to protein family HMM PF05866 YP_002271127.1 identified by match to protein family HMM PF06914 YP_002271133.1 identified by match to protein family HMM PF07789 YP_002271136.1 identified by match to protein family HMM PF06254 YP_002271137.1 identified by match to protein family HMM PF00717 YP_002271138.1 identified by match to protein family HMM PF07151 YP_002271139.1 identified by match to protein family HMM PF05358 YP_002271140.1 identified by match to protein family HMM PF07358 YP_002271143.1 identified by match to protein family HMM PF00589 YP_002271144.1 identified by match to protein family HMM PF06167 YP_002271145.1 identified by match to protein family HMM PF02369 YP_002271147.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002271148.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002271149.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002271150.1 identified by glimmer YP_002271151.1 identified by glimmer YP_002271152.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002271153.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_002271154.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_002271155.1 identified by glimmer YP_002271156.1 identified by match to protein family HMM PF03734 YP_002271157.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_002271158.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_002271159.1 identified by match to protein family HMM PF05717 YP_002271160.1 identified by match to protein family HMM PF03050 YP_002271162.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271163.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002271164.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_002271165.1 identified by glimmer YP_002271168.1 identified by match to protein family HMM PF01734 YP_002271169.1 identified by glimmer YP_002271170.1 identified by glimmer YP_002271171.1 identified by glimmer YP_002271172.1 identified by match to protein family HMM PF06067 YP_002271173.1 identified by match to protein family HMM PF03230 YP_002271174.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_002271175.1 identified by match to protein family HMM PF06174 YP_002271176.1 identified by match to protein family HMM PF06154 YP_002271179.1 identified by match to protein family HMM PF04363 YP_002271180.1 identified by glimmer YP_002271182.1 identified by match to protein family HMM PF06445 YP_002271183.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002271184.1 identified by glimmer YP_002271185.1 identified by match to protein family HMM PF06416 YP_002271187.1 identified by match to protein family HMM PF06820 YP_002271188.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002271189.1 identified by match to protein family HMM PF06316 YP_002271190.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002271191.1 identified by glimmer YP_002271192.1 identified by match to protein family HMM PF06805 YP_002271193.1 identified by match to protein family HMM PF00877 YP_002271195.1 identified by glimmer YP_002271197.1 identified by match to protein family HMM PF05939 YP_002271198.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675 YP_002271199.1 identified by glimmer YP_002271200.1 identified by match to protein family HMM PF06222 YP_002271201.1 identified by match to protein family HMM PF07679 YP_002271202.1 identified by glimmer YP_002271203.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725 YP_002271204.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563 YP_002271206.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002271207.1 identified by match to protein family HMM PF04586 YP_002271208.1 identified by match to protein family HMM PF03354 YP_002271210.1 identified by match to protein family HMM PF01844 YP_002271213.1 identified by match to protein family HMM PF04383 YP_002271214.1 identified by match to protein family HMM PF03245 YP_002271215.1 identified by match to protein family HMM PF00959 YP_002271216.1 identified by match to protein family HMM PF04971 YP_002271217.1 identified by match to protein family HMM PF05696 YP_002271218.1 identified by match to protein family HMM PF07125 YP_002271219.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002271220.1 identified by match to protein family HMM PF02258 YP_002271221.1 identified by match to protein family HMM PF00161 YP_002271222.1 identified by match to protein family HMM PF06530 YP_002271223.1 identified by match to protein family HMM PF00149 YP_002271224.1 identified by match to protein family HMM PF05766 YP_002271225.1 identified by match to protein family HMM PF03374 YP_002271228.1 identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712 YP_002271229.1 identified by match to protein family HMM PF05772 YP_002271230.1 identified by match to protein family HMM TIGR03655 YP_002271232.1 identified by match to protein family HMM PF00772; match to protein family HMM PF03796 YP_002271233.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002271235.1 identified by match to protein family HMM PF05269 YP_002271236.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_002271237.1 identified by glimmer YP_002271239.1 identified by glimmer YP_002271240.1 identified by glimmer YP_002271241.1 identified by match to protein family HMM PF06301 YP_002271242.1 identified by match to protein family HMM PF06064 YP_002271243.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913 YP_002271244.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271245.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002271249.1 identified by match to protein family HMM PF04447 YP_002271252.1 identified by match to protein family HMM PF05930 YP_002271253.1 identified by match to protein family HMM PF00589 YP_002271254.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002271255.1 identified by match to protein family HMM PF01206 YP_002271256.1 identified by match to protein family HMM PF04143 YP_002271257.1 identified by match to protein family HMM PF00324 YP_002271258.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002271259.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_002271260.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002271261.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002271262.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002271263.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002271264.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002271265.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002271266.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002271267.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_002271268.1 identified by match to protein family HMM PF02706 YP_002271269.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002271270.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002271271.1 identified by glimmer YP_002271272.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002271273.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_002271274.1 identified by match to protein family HMM PF00293 YP_002271275.1 identified by match to protein family HMM PF01370 YP_002271276.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472 YP_002271277.1 identified by match to protein family HMM PF00534 YP_002271278.1 identified by match to protein family HMM PF01041 YP_002271279.1 identified by match to protein family HMM PF01943 YP_002271282.1 identified by match to protein family HMM PF00535 YP_002271283.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002271284.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002271285.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_002271286.1 identified by match to protein family HMM PF00534 YP_002271287.1 identified by match to protein family HMM PF04230 YP_002271288.1 identified by match to protein family HMM PF01943 YP_002271289.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_002271290.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002271292.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_002271293.1 identified by match to protein family HMM PF00534 YP_002271294.1 identified by match to protein family HMM PF00293 YP_002271295.1 identified by match to protein family HMM PF01370 YP_002271296.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472 YP_002271297.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_002271298.1 identified by match to protein family HMM PF00535 YP_002271299.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_002271301.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium YP_002271302.1 identified by match to protein family HMM PF00535 YP_002271303.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_002271304.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis YP_002271305.1 identified by match to protein family HMM PF02563 YP_002271306.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_002271307.1 identified by match to protein family HMM PF05973 YP_002271308.1 identified by match to protein family HMM PF01381 YP_002271309.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_002271310.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002271311.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002271312.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_002271316.1 identified by match to protein family HMM PF00092 YP_002271317.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002271318.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002271319.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_002271320.1 identified by match to protein family HMM PF07690 YP_002271321.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002271322.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_002271323.1 identified by match to protein family HMM PF07411 YP_002271324.1 identified by match to protein family HMM PF01136 YP_002271325.1 in E. coli K-12 this is in prophage P2 remnant YP_002271326.1 identified by match to protein family HMM PF05954 YP_002271327.1 identified by match to protein family HMM PF06995 YP_002271328.1 identified by match to protein family HMM TIGR01760 YP_002271329.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611 YP_002271330.1 identified by match to protein family HMM PF04984 YP_002271331.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002271332.1 identified by match to protein family HMM PF07484 YP_002271333.1 identified by match to protein family HMM PF02413 YP_002271334.1 identified by match to protein family HMM PF02413 YP_002271336.1 identified by match to protein family HMM PF09684; match to protein family HMM TIGR01634 YP_002271337.1 identified by match to protein family HMM PF04865 YP_002271338.1 identified by match to protein family HMM PF04965 YP_002271339.1 identified by match to protein family HMM PF04717; match to protein family HMM TIGR01644 YP_002271340.1 identified by match to protein family HMM PF05069; match to protein family HMM TIGR01635 YP_002271341.1 identified by match to protein family HMM PF06891 YP_002271343.1 identified by match to protein family HMM TIGR03495 YP_002271345.1 identified by match to protein family HMM PF00959 YP_002271346.1 identified by match to protein family HMM PF04550 YP_002271347.1 identified by match to protein family HMM PF05489 YP_002271348.1 identified by match to protein family HMM PF05926 YP_002271349.1 identified by match to protein family HMM PF05944 YP_002271350.1 identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551 YP_002271351.1 identified by match to protein family HMM PF05929 YP_002271352.1 identified by match to protein family HMM PF03237; match to protein family HMM PF06056 YP_002271353.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540 YP_002271354.1 identified by glimmer YP_002271356.1 identified by glimmer YP_002271357.1 identified by match to protein family HMM PF05057; match to protein family HMM PF07819 YP_002271358.1 identified by match to protein family HMM PF05840 YP_002271360.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_002271366.1 identified by match to protein family HMM PF00589 YP_002271368.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_002271369.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002271370.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_002271371.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_002271372.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002271373.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002271374.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_002271375.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_002271376.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_002271377.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_002271378.1 identified by match to protein family HMM PF03747 YP_002271379.1 identified by match to protein family HMM PF00294 YP_002271380.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002271381.1 identified by match to protein family HMM PF01183 YP_002271382.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002271383.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002271387.1 identified by match to protein family HMM PF02583 YP_002271388.1 membrane protein conferring nickel and cobalt resistance YP_002271391.1 identified by match to protein family HMM PF00577 YP_002271392.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002271393.1 identified by match to protein family HMM PF00419 YP_002271396.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002271397.1 identified by glimmer YP_002271399.1 identified by glimmer YP_002271400.1 identified by glimmer YP_002271401.1 identified by match to protein family HMM PF07728 YP_002271402.1 identified by match to protein family HMM PF00092; match to protein family HMM PF05762 YP_002271403.1 identified by match to protein family HMM PF04434 YP_002271404.1 identified by match to protein family HMM PF06998 YP_002271405.1 identified by match to protein family HMM PF07308 YP_002271406.1 unknown function; when overproduced it confers drug-resistance YP_002271407.1 identified by match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_002271408.1 identified by glimmer YP_002271409.1 identified by glimmer YP_002271410.1 identified by match to protein family HMM PF06183 YP_002271411.1 identified by match to protein family HMM PF06820 YP_002271412.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002271413.1 identified by match to protein family HMM PF06316 YP_002271414.1 identified by match to protein family HMM PF09327 YP_002271415.1 identified by glimmer YP_002271416.1 identified by match to protein family HMM PF06805 YP_002271417.1 identified by match to protein family HMM PF00877 YP_002271418.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002271419.1 identified by match to protein family HMM PF05939 YP_002271420.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002271421.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002271422.1 identified by match to protein family HMM PF02368 YP_002271423.1 identified by match to protein family HMM PF06141 YP_002271424.1 identified by match to protein family HMM PF06763 YP_002271427.1 identified by match to protein family HMM PF00574; match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002271429.1 identified by match to protein family HMM PF05876 YP_002271430.1 identified by match to protein family HMM PF07278 YP_002271431.1 identified by match to protein family HMM PF03245 YP_002271434.1 identified by match to protein family HMM PF00959 YP_002271435.1 identified by match to protein family HMM PF04971 YP_002271436.1 identified by match to protein family HMM PF05696 YP_002271437.1 identified by match to protein family HMM PF07125 YP_002271438.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002271440.1 identified by glimmer YP_002271441.1 identified by match to protein family HMM PF01555 YP_002271443.1 identified by match to protein family HMM PF03589 YP_002271444.1 identified by match to protein family HMM PF05866 YP_002271445.1 identified by match to protein family HMM PF06914 YP_002271448.1 identified by match to protein family HMM PF04448 YP_002271452.1 identified by match to protein family HMM PF06163 YP_002271453.1 identified by match to protein family HMM PF07789 YP_002271456.1 identified by match to protein family HMM PF06254 YP_002271458.1 identified by glimmer YP_002271460.1 identified by match to protein family HMM PF07151 YP_002271461.1 identified by glimmer YP_002271462.1 identified by glimmer YP_002271464.1 identified by match to protein family HMM PF07358 YP_002271465.1 identified by match to protein family HMM PF00929; match to protein family HMM PF06630 YP_002271466.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002271469.1 identified by match to protein family HMM PF03400 YP_002271471.1 identified by match to protein family HMM PF06820 YP_002271473.1 identified by match to protein family HMM PF06316 YP_002271474.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002271475.1 identified by glimmer YP_002271476.1 identified by match to protein family HMM PF06805 YP_002271477.1 identified by match to protein family HMM PF00877 YP_002271478.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002271479.1 identified by match to protein family HMM PF05939 YP_002271480.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002271481.1 identified by match to protein family HMM TIGR01715 YP_002271482.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002271483.1 identified by match to protein family HMM PF02368 YP_002271484.1 identified by match to protein family HMM PF06141 YP_002271485.1 identified by match to protein family HMM PF06763 YP_002271488.1 identified by match to protein family HMM PF00574 YP_002271489.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002271491.1 identified by match to protein family HMM PF05876 YP_002271492.1 identified by match to protein family HMM PF07278 YP_002271493.1 identified by match to protein family HMM PF03245 YP_002271494.1 identified by match to protein family HMM PF00959 YP_002271496.1 identified by match to protein family HMM PF04971 YP_002271497.1 identified by match to protein family HMM PF05696 YP_002271498.1 identified by match to protein family HMM PF07125 YP_002271500.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002271501.1 identified by match to protein family HMM PF06530 YP_002271503.1 DLP12 prophage; Holliday junction resolvase YP_002271504.1 identified by match to protein family HMM PF07102 YP_002271505.1 DLP12 prophage YP_002271506.1 identified by match to protein family HMM PF00165 YP_002271508.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002271509.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation YP_002271511.1 identified by match to protein family HMM PF06992 YP_002271512.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002271513.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271514.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002271515.1 identified by match to protein family HMM PF06254 YP_002271517.1 identified by match to protein family HMM PF00717 YP_002271520.1 identified by match to protein family HMM PF06064 YP_002271521.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913 YP_002271522.1 identified by match to protein family HMM PF09588 YP_002271525.1 identified by match to protein family HMM PF04447 YP_002271527.1 identified by match to protein family HMM PF06806 YP_002271528.1 identified by match to protein family HMM PF00589 YP_002271530.1 identified by match to protein family HMM PF00528 YP_002271531.1 identified by match to protein family HMM PF00005 YP_002271532.1 identified by match to protein family HMM PF00528 YP_002271533.1 identified by match to protein family HMM PF04069 YP_002271534.1 identified by match to protein family HMM PF00933; match to protein family HMM PF01915 YP_002271535.1 identified by glimmer YP_002271536.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_002271537.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_002271538.1 identified by match to protein family HMM PF06930 YP_002271539.1 identified by match to protein family HMM PF09335 YP_002271541.1 identified by match to protein family HMM PF00106 YP_002271542.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002271543.1 identified by match to protein family HMM PF01207 YP_002271544.1 catalyzes the formation of catechol from salicylate YP_002271545.1 identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262 YP_002271546.1 identified by match to protein family HMM PF01557 YP_002271547.1 identified by match to protein family HMM PF07883; match to protein family HMM TIGR02272 YP_002271548.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002271549.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002271550.1 identified by match to protein family HMM PF03788 YP_002271551.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659 YP_002271552.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002271553.1 identified by match to protein family HMM PF02698 YP_002271555.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_002271556.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_002271558.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_002271559.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_002271560.1 identified by match to protein family HMM PF00532 YP_002271561.1 identified by glimmer YP_002271562.1 negative regulator of the mglBAC operon for galactose utilization YP_002271563.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002271564.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002271565.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_002271566.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_002271567.1 identified by glimmer YP_002271568.1 identified by match to protein family HMM PF00324 YP_002271569.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002271570.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698 YP_002271571.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002271572.1 identified by match to protein family HMM PF00294 YP_002271573.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002271574.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively YP_002271575.1 activator of nucleoside metabolism YP_002271576.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002271577.1 identified by match to protein family HMM PF04227 YP_002271578.1 identified by match to protein family HMM PF00294 YP_002271579.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002271580.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_002271581.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_002271583.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_002271585.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_002271586.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002271587.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002271588.1 identified by match to protein family HMM PF01569 YP_002271589.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_002271590.1 identified by match to protein family HMM PF00563 YP_002271591.1 identified by match to protein family HMM PF00496 YP_002271592.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528 YP_002271593.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528 YP_002271594.1 identified by match to protein family HMM PF00005 YP_002271596.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002271597.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_002271598.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002271599.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_002271600.1 identified by match to protein family HMM PF04245 YP_002271601.1 identified by glimmer YP_002271602.1 identified by match to protein family HMM PF07208 YP_002271603.1 identified by match to protein family HMM PF00884 YP_002271604.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002271605.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_002271606.1 identified by match to protein family HMM PF03918 YP_002271607.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_002271608.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_002271609.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002271610.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_002271611.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_002271612.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_002271613.1 ATP-binding protein; required for proper cytochrome c maturation YP_002271614.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_002271615.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_002271616.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_002271617.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_002271618.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_002271619.1 identified by match to protein family HMM PF03927 YP_002271620.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA. YP_002271621.1 identified by glimmer YP_002271622.1 serine protease inhibitor, inhibits trypsin and other proteases YP_002271623.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002271624.1 efflux pump for the antibacterial peptide microcin J25 YP_002271625.1 identified by match to protein family HMM PF03171; match to protein family HMM TIGR00568 YP_002271626.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002271627.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_002271628.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_002271630.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518 YP_002271631.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_002271632.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF09456 YP_002271634.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_002271635.1 identified by match to protein family HMM PF06672 YP_002271637.1 negatively supercoils closed circular double-stranded DNA YP_002271638.1 Involved in ubiquinone biosynthesis YP_002271639.1 identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601 YP_002271640.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002271641.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002271642.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_002271643.1 identified by match to protein family HMM PF06293 YP_002271644.1 identified by match to protein family HMM PF07690 YP_002271645.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002271646.1 identified by glimmer YP_002271648.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_002271649.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002271650.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_002271651.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_002271652.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_002271653.1 identified by glimmer YP_002271654.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002271656.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002271657.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271659.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002271660.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002271661.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200 YP_002271662.1 identified by match to protein family HMM PF07437 YP_002271663.1 identified by match to protein family HMM PF00293 YP_002271664.1 identified by match to protein family HMM PF00300 YP_002271665.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_002271666.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_002271667.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_002271668.1 identified by match to protein family HMM PF01522 YP_002271669.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_002271670.1 identified by match to protein family HMM PF00893 YP_002271673.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923 YP_002271674.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_002271675.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_002271676.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_002271677.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002271678.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002271679.1 identified by match to protein family HMM PF05957 YP_002271680.1 identified by match to protein family HMM PF00583 YP_002271681.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002271683.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system YP_002271684.1 identified by match to protein family HMM PF08974 YP_002271685.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271686.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271687.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002271688.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271689.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271690.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271691.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271692.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271693.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_002271694.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271695.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_002271696.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002271697.1 Catalyzes the transfer of electrons from NADH to quinone YP_002271698.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002271699.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002271700.1 identified by match to protein family HMM PF01966 YP_002271701.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_002271702.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002271703.1 identified by match to protein family HMM PF03887 YP_002271704.1 identified by match to protein family HMM PF04217 YP_002271705.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002271706.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002271707.1 identified by match to protein family HMM PF03606 YP_002271708.1 identified by match to protein family HMM PF00293 YP_002271709.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002271710.1 identified by match to protein family HMM PF02798 YP_002271711.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002271712.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_002271713.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_002271714.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002271715.1 identified by match to protein family HMM PF00005 YP_002271716.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002271717.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002271718.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002271719.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002271720.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_002271721.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002271722.1 membrane protein required for colicin V production YP_002271723.1 identified by match to protein family HMM PF05036 YP_002271724.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002271725.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002271726.1 identified by match to protein family HMM PF09335 YP_002271727.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002271728.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774 YP_002271729.1 identified by glimmer YP_002271730.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002271731.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_002271732.1 identified by match to protein family HMM PF07690 YP_002271733.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002271734.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002271735.1 identified by match to protein family HMM PF08891 YP_002271736.1 identified by match to protein family HMM PF04315 YP_002271737.1 identified by match to protein family HMM PF01925 YP_002271738.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_002271739.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002271740.1 involved in methylation of ribosomal protein L3 YP_002271741.1 identified by match to protein family HMM PF01713 YP_002271743.1 identified by match to protein family HMM PF00419 YP_002271747.1 identified by glimmer YP_002271748.1 identified by match to protein family HMM PF00345 YP_002271749.1 identified by match to protein family HMM PF00577 YP_002271750.1 identified by match to protein family HMM PF00419 YP_002271751.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249 YP_002271752.1 identified by glimmer YP_002271753.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_002271754.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002271755.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_002271756.1 identified by match to protein family HMM PF03349 YP_002271757.1 identified by glimmer YP_002271758.1 identified by match to protein family HMM PF04333 YP_002271766.1 identified by match to protein family HMM PF06316 YP_002271770.1 identified by glimmer YP_002271771.1 identified by match to protein family HMM PF06820 YP_002271772.1 identified by match to protein family HMM PF01391; match to protein family HMM PF03406; match to protein family HMM PF06820; match to protein family HMM PF08400 YP_002271779.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002271780.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002271782.1 identified by glimmer YP_002271786.1 identified by match to protein family HMM PF06291 YP_002271787.1 identified by match to protein family HMM PF03245 YP_002271790.1 identified by match to protein family HMM PF00959 YP_002271791.1 identified by match to protein family HMM PF04971 YP_002271792.1 identified by match to protein family HMM PF05696 YP_002271793.1 identified by match to protein family HMM PF07125 YP_002271795.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002271796.1 identified by match to protein family HMM PF02258 YP_002271797.1 identified by match to protein family HMM PF00161 YP_002271799.1 identified by glimmer YP_002271800.1 identified by match to protein family HMM PF06322 YP_002271801.1 identified by match to protein family HMM PF05766 YP_002271802.1 identified by match to protein family HMM PF03374 YP_002271805.1 identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712 YP_002271806.1 identified by glimmer YP_002271807.1 identified by glimmer YP_002271811.1 identified by match to protein family HMM PF06992 YP_002271812.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002271813.1 identified by match to protein family HMM PF05269 YP_002271815.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_002271817.1 identified by match to protein family HMM PF00069 YP_002271819.1 identified by glimmer YP_002271820.1 identified by glimmer YP_002271822.1 identified by match to protein family HMM PF06064 YP_002271823.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913 YP_002271824.1 identified by match to protein family HMM PF09588 YP_002271827.1 identified by match to protein family HMM PF04447 YP_002271832.1 identified by match to protein family HMM PF08346 YP_002271834.1 identified by match to protein family HMM PF05063 YP_002271838.1 identified by match to protein family HMM PF00589 YP_002271839.1 identified by match to protein family HMM PF00589 YP_002271848.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_002271849.1 identified by glimmer YP_002271850.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_002271851.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002271852.1 identified by glimmer YP_002271853.1 catalyzes the formation of pyruvate from serine YP_002271854.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002271855.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_002271856.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_002271857.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518 YP_002271858.1 member of the AEC family of auxin efflux transporters; unknown function YP_002271859.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_002271860.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA YP_002271863.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_002271864.1 identified by glimmer YP_002271865.1 identified by match to protein family HMM PF00155 YP_002271866.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_002271867.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002271868.1 identified by match to protein family HMM PF00165 YP_002271869.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417 YP_002271870.1 metalloprotein YP_002271871.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase YP_002271872.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_002271873.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829 YP_002271874.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002271875.1 identified by match to protein family HMM PF00654 YP_002271877.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_002271878.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002271879.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_002271880.1 identified by match to protein family HMM PF07037 YP_002271881.1 identified by match to protein family HMM PF07037 YP_002271882.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002271883.1 identified by match to protein family HMM PF01797 YP_002271884.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002271885.1 identified by glimmer YP_002271886.1 identified by glimmer YP_002271887.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002271888.1 identified by match to protein family HMM PF01758 YP_002271890.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002271891.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002271892.1 role in sulfur assimilation YP_002271893.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_002271894.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002271895.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_002271896.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002271897.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002271898.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_002271899.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968 YP_002271900.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_002271901.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139 YP_002271902.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_002271903.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_002271904.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002271905.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002271906.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_002271907.1 identified by match to protein family HMM PF00144 YP_002271908.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413 YP_002271909.1 identified by match to protein family HMM PF06572 YP_002271911.1 identified by match to protein family HMM PF00583 YP_002271912.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_002271913.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002271914.1 activates the transcription of the ethanolamine utilization operon YP_002271915.1 identified by match to protein family HMM PF00936 YP_002271916.1 identified by match to protein family HMM PF00936 YP_002271917.1 catalyzes the formation of acetaldehyde from ethanolamine YP_002271918.1 identified by match to protein family HMM PF06751 YP_002271919.1 ethanolamine utilization protein EutA YP_002271920.1 identified by match to protein family HMM PF04346 YP_002271921.1 identified by match to protein family HMM PF00465 YP_002271922.1 identified by match to protein family HMM TIGR02529 YP_002271923.1 identified by match to protein family HMM PF00171 YP_002271924.1 identified by match to protein family HMM PF03319 YP_002271925.1 identified by match to protein family HMM PF00936 YP_002271926.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002271927.1 identified by match to protein family HMM PF01923 YP_002271928.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249 YP_002271929.1 identified by match to protein family HMM TIGR02528 YP_002271930.1 identified by match to protein family HMM PF00936 YP_002271931.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002271932.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_002271933.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002271934.1 identified by match to protein family HMM PF06674 YP_002271935.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052 YP_002271936.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_002271937.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002271938.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002271939.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002271940.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002271942.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002271943.1 identified by match to protein family HMM PF00583; match to protein family HMM PF05127 YP_002271944.1 identified by match to protein family HMM PF04228 YP_002271945.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002271946.1 identified by match to protein family HMM PF06804 YP_002271947.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002271948.1 negative transcriptional regulator of the gcvTHP operon YP_002271949.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002271950.1 identified by match to protein family HMM PF00037 YP_002271951.1 identified by match to protein family HMM PF00361 YP_002271952.1 identified by match to protein family HMM PF00146 YP_002271953.1 identified by match to protein family HMM PF00361 YP_002271954.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_002271955.1 identified by match to protein family HMM PF00361 YP_002271956.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346 YP_002271957.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_002271958.1 identified by match to protein family HMM PF01058 YP_002271959.1 identified by match to protein family HMM PF07450 YP_002271960.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_002271961.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon YP_002271962.1 identified by match to protein family HMM PF01594 YP_002271963.1 identified by match to protein family HMM PF01435 YP_002271964.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_002271965.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_002271966.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002271967.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002271968.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002271969.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002271970.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002271971.1 identified by match to protein family HMM PF02541 YP_002271972.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_002271975.1 identified by match to protein family HMM PF05433 YP_002271977.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002271978.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002271979.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002271980.1 identified by match to protein family HMM PF07191 YP_002271981.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002271982.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_002271984.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002271985.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002271986.1 identified by match to protein family HMM PF01381 YP_002271987.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002271988.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002271989.1 identified by match to protein family HMM PF00037 YP_002271991.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002271992.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002271993.1 penicillin-insensitive transglycosylase/transpeptidase YP_002271994.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_002271995.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_002271996.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_002271997.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002271998.1 identified by match to protein family HMM PF04384; match to protein family HMM TIGR03412 YP_002271999.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 YP_002272000.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002272001.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002272002.1 identified by glimmer YP_002272003.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_002272004.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999 YP_002272005.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002272006.1 regulates the expression of the iscRSUA operon YP_002272007.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050 YP_002272008.1 identified by match to protein family HMM PF00459 YP_002272010.1 identified by match to protein family HMM PF00874 YP_002272011.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_002272012.1 activator of 3-phenylpropionic acid catabolism YP_002272013.1 identified by match to protein family HMM PF00866 YP_002272014.1 identified by match to protein family HMM PF00355 YP_002272015.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_002272016.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002272017.1 identified by match to protein family HMM PF07681 YP_002272018.1 identified by match to protein family HMM PF01263 YP_002272019.1 identified by match to protein family HMM PF02653 YP_002272020.1 identified by match to protein family HMM PF00005 YP_002272021.1 identified by match to protein family HMM PF00532 YP_002272022.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002272023.1 identified by match to protein family HMM PF00480 YP_002272024.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002272026.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002272027.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_002272028.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728 YP_002272030.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002272031.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002272032.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_002272033.1 identified by match to protein family HMM PF00383 YP_002272034.1 identified by match to protein family HMM TIGR01545 YP_002272035.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002272037.1 identified by glimmer YP_002272038.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002272039.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002272040.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002272041.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002272042.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002272043.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_002272044.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002272045.1 involved in the reduction of the SoxR iron-sulfur cluster YP_002272046.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_002272047.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873 YP_002272048.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002272049.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002272050.1 identified by match to protein family HMM PF05175 YP_002272051.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002272052.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002272053.1 identified by match to protein family HMM PF01810 YP_002272054.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_002272055.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002272056.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002272057.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002272058.1 identified by match to protein family HMM PF03942 YP_002272059.1 identified by match to protein family HMM PF00583; match to protein family HMM PF02629 YP_002272060.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002272062.1 identified by match to protein family HMM PF00083 YP_002272063.1 identified by glimmer YP_002272065.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_002272066.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_002272067.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_002272068.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_002272069.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_002272070.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002272071.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002272072.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002272075.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002272076.1 identified by match to protein family HMM PF00691 YP_002272077.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002272078.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002272079.1 Essential for efficient processing of 16S rRNA YP_002272080.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002272081.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_002272082.1 identified by match to protein family HMM PF01578 YP_002272083.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002272084.1 catalyzes the phosphorylation of NAD to NADP YP_002272085.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002272086.1 identified by match to protein family HMM PF04355 YP_002272087.1 identified by match to protein family HMM PF03658 YP_002272088.1 identified by match to protein family HMM PF03364 YP_002272089.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002272090.1 identified by match to protein family HMM PF06183 YP_002272093.1 identified by match to protein family HMM PF03278 YP_002272094.1 identified by glimmer YP_002272095.1 identified by glimmer YP_002272097.1 identified by match to protein family HMM PF06416 YP_002272100.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002272101.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002272102.1 identified by match to protein family HMM PF05717 YP_002272104.1 identified by match to protein family HMM PF07041 YP_002272105.1 identified by match to protein family HMM PF04971 YP_002272106.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410 YP_002272109.1 identified by glimmer YP_002272110.1 identified by match to protein family HMM PF03589 YP_002272111.1 identified by match to protein family HMM PF00149 YP_002272112.1 identified by match to protein family HMM PF05766 YP_002272119.1 identified by match to protein family HMM PF00589 YP_002272121.1 identified by glimmer YP_002272122.1 identified by glimmer YP_002272123.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_002272124.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_002272125.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_002272126.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002272127.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773 YP_002272128.1 regulator of gab gene expression YP_002272129.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972 YP_002272130.1 identified by match to protein family HMM PF01679 YP_002272131.1 identified by match to protein family HMM PF01022 YP_002272133.1 identified by match to protein family HMM PF00816 YP_002272134.1 identified by match to protein family HMM PF06610 YP_002272135.1 identified by match to protein family HMM PF09400 YP_002272136.1 identified by match to protein family HMM PF05957 YP_002272137.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002272138.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002272139.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_002272140.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002272141.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002272142.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002272143.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_002272144.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_002272145.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_002272146.1 identified by glimmer YP_002272147.1 identified by match to protein family HMM PF07690 YP_002272148.1 identified by match to protein family HMM PF03591 YP_002272150.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_002272151.1 identified by glimmer YP_002272152.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_002272153.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002272154.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002272155.1 involved in the first step of glutathione biosynthesis YP_002272157.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_002272158.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002272159.1 identified by glimmer YP_002272160.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002272161.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002272162.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002272163.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_002272164.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_002272165.1 identified by glimmer YP_002272166.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002272167.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_002272168.1 regulator for glucitol utilization YP_002272169.1 regulates genes involved in glucitol utilization YP_002272170.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_002272171.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_002272172.1 detoxifies nitric oxide using NADH YP_002272173.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_002272174.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_002272175.1 involved in electron transport from formate to hydrogen YP_002272176.1 identified by glimmer YP_002272177.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002272178.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002272179.1 identified by match to protein family HMM PF00232 YP_002272180.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_002272181.1 identified by match to protein family HMM PF07450 YP_002272182.1 identified by match to protein family HMM PF01058 YP_002272183.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_002272184.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346 YP_002272185.1 identified by match to protein family HMM PF00146 YP_002272186.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_002272187.1 identified by match to protein family HMM PF00037 YP_002272188.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_002272189.1 identified by glimmer YP_002272190.1 plays a role in hydrogenase nickel cofactor insertion YP_002272191.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_002272192.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_002272193.1 identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_002272194.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_002272195.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_002272197.1 identified by glimmer YP_002272198.1 This protein performs the mismatch recognition step during the DNA repair process YP_002272199.1 identified by match to protein family HMM PF00149 YP_002272201.1 identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148 YP_002272202.1 identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421 YP_002272203.1 identified by match to protein family HMM PF01047 YP_002272204.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_002272205.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_002272206.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002272207.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002272208.1 catalyzes the modification of U13 in tRNA(Glu) YP_002272209.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002272210.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002272211.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002272213.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_002272214.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002272215.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002272216.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_002272217.1 identified by glimmer YP_002272218.1 identified by match to protein family HMM PF09707; match to protein family HMM TIGR01873 YP_002272219.1 identified by match to protein family HMM TIGR00287; match to protein family HMM TIGR03638 YP_002272220.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907 YP_002272221.1 identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593 YP_002272222.1 identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869 YP_002272223.1 identified by match to protein family HMM PF09485; match to protein family HMM TIGR02548 YP_002272224.1 identified by match to protein family HMM PF09481; match to protein family HMM TIGR02547 YP_002272225.1 identified by match to protein family HMM TIGR01587 YP_002272226.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_002272227.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002272228.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_002272229.1 identified by glimmer YP_002272230.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367 YP_002272231.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002272233.1 identified by match to protein family HMM PF04309 YP_002272234.1 identified by match to protein family HMM PF01012 YP_002272235.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_002272236.1 identified by match to protein family HMM PF00106 YP_002272237.1 identified by match to protein family HMM PF07690 YP_002272238.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002272240.1 identified by match to protein family HMM PF04011 YP_002272242.1 identified by match to protein family HMM PF04536 YP_002272243.1 identified by match to protein family HMM PF04536 YP_002272244.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002272245.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002272246.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_002272247.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system YP_002272248.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF YP_002272249.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_002272250.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002272251.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002272252.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247 YP_002272253.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_002272254.1 identified by glimmer YP_002272255.1 identified by glimmer YP_002272256.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002272257.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002272258.1 identified by match to protein family HMM PF04287 YP_002272259.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002272260.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002272261.1 identified by match to protein family HMM PF03641 YP_002272262.1 identified by match to protein family HMM TIGR00814 YP_002272263.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002272264.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_002272265.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_002272266.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002272267.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_002272268.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_002272269.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628 YP_002272270.1 identified by match to protein family HMM PF05025 YP_002272271.1 regulates expression of genes involved in L-fucose utilization YP_002272273.1 identified by match to protein family HMM PF04241 YP_002272274.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002272275.1 identified by match to protein family HMM PF06004 YP_002272276.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392 YP_002272277.1 identified by match to protein family HMM PF02657; match to protein family HMM TIGR03391 YP_002272278.1 identified by match to protein family HMM PF00899 YP_002272279.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002272280.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_002272281.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002272282.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002272283.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002272284.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002272285.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002272286.1 identified by match to protein family HMM TIGR02532 YP_002272288.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002272289.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002272290.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002272291.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002272292.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002272293.1 hydrolyzes diadenosine polyphosphate YP_002272294.1 identified by glimmer YP_002272295.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002272296.1 identified by match to protein family HMM PF03741 YP_002272297.1 identified by match to protein family HMM PF06004 YP_002272298.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_002272299.1 identified by match to protein family HMM PF07690 YP_002272300.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_002272301.1 controls transcription of galETKM YP_002272302.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002272303.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002272304.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002272305.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_002272306.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_002272307.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_002272308.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002272309.1 identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814 YP_002272311.1 identified by match to protein family HMM PF00486 YP_002272313.1 identified by glimmer YP_002272314.1 identified by glimmer YP_002272315.1 identified by glimmer YP_002272316.1 identified by match to protein family HMM PF07720 YP_002272317.1 identified by match to protein family HMM PF00486; match to protein family HMM PF07719 YP_002272319.1 identified by match to protein family HMM PF01464 YP_002272320.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002272321.1 identified by glimmer YP_002272324.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_002272326.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105 YP_002272327.1 identified by glimmer YP_002272328.1 identified by match to protein family HMM PF00196 YP_002272329.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins YP_002272330.1 identified by match to protein family HMM PF01313; match to protein family HMM TIGR01403 YP_002272331.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_002272334.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase YP_002272335.1 identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399 YP_002272336.1 identified by match to protein family HMM PF02523; match to protein family HMM TIGR02568 YP_002272337.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516 YP_002272338.1 identified by match to protein family HMM PF00165 YP_002272340.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_002272341.1 molybdenum cofactor-binding protein; participates in purine salvage YP_002272342.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage YP_002272343.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage YP_002272344.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954 YP_002272345.1 identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316 YP_002272346.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_002272347.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_002272348.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_002272349.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002272350.1 identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309 YP_002272351.1 identified by match to protein family HMM TIGR03172 YP_002272352.1 identified by match to protein family HMM TIGR03310 YP_002272353.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_002272354.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_002272355.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_002272356.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_002272357.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_002272358.1 Catalyzes the deamination of guanine YP_002272359.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002272360.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_002272361.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_002272362.1 identified by glimmer YP_002272363.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_002272364.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002272366.1 5'-3' single-stranded-DNA-specific exonuclease YP_002272367.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_002272368.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002272369.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_002272370.1 identified by match to protein family HMM PF07254 YP_002272371.1 identified by match to protein family HMM PF03937 YP_002272372.1 identified by glimmer YP_002272373.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_002272374.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002272375.1 identified by match to protein family HMM PF04266 YP_002272376.1 identified by match to protein family HMM PF00232 YP_002272377.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002272378.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002272379.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002272381.1 identified by glimmer YP_002272382.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988 YP_002272383.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_002272384.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_002272385.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002272386.1 identified by match to protein family HMM PF05164 YP_002272387.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_002272388.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002272389.1 identified by glimmer YP_002272390.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002272391.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002272392.1 MDM; functions in conversion of succinate to propionate YP_002272393.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_002272394.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_002272395.1 identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458 YP_002272396.1 identified by match to protein family HMM PF04402 YP_002272397.1 Involved in the export of arginine YP_002272398.1 participates in the regulation of osmotic pressure changes within the cel YP_002272399.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002272400.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002272401.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002272402.1 identified by match to protein family HMM PF03479 YP_002272405.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00005 YP_002272406.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00005 YP_002272408.1 identified by match to protein family HMM PF05068 YP_002272409.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330 YP_002272410.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002272411.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_002272412.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein YP_002272413.1 identified by glimmer YP_002272414.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002272415.1 identified by match to protein family HMM PF01435 YP_002272416.1 catalyzes the formation of putrescine from agmatine YP_002272418.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002272420.1 identified by glimmer YP_002272421.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002272422.1 identified by glimmer YP_002272423.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_002272424.1 identified by match to protein family HMM PF03926 YP_002272425.1 identified by match to protein family HMM PF04231 YP_002272426.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002272427.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_002272428.1 identified by match to protein family HMM PF02622 YP_002272429.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002272430.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420 YP_002272431.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_002272432.1 identified by match to protein family HMM PF02325 YP_002272433.1 identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251 YP_002272434.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002272435.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002272436.1 identified by match to protein family HMM PF06717 YP_002272437.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_002272440.1 identified by match to protein family HMM PF04320 YP_002272441.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002272442.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002272443.1 identified by match to protein family HMM PF04362 YP_002272444.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002272445.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_002272446.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002272447.1 identified by match to protein family HMM PF04474 YP_002272448.1 identified by match to protein family HMM PF00589 YP_002272450.1 identified by match to protein family HMM PF01527 YP_002272451.1 identified by match to protein family HMM PF05717 YP_002272453.1 identified by match to protein family HMM PF06316 YP_002272455.1 identified by glimmer YP_002272456.1 identified by match to protein family HMM PF07906 YP_002272457.1 identified by glimmer YP_002272460.1 identified by match to protein family HMM PF05717 YP_002272461.1 identified by match to protein family HMM PF03050 YP_002272463.1 identified by match to protein family HMM PF05717 YP_002272465.1 identified by glimmer YP_002272466.1 identified by match to protein family HMM PF01384 YP_002272467.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_002272468.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli YP_002272469.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_002272470.1 plays a role in hydrogenase nickel cofactor insertion YP_002272472.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_002272473.1 involved in hydrogen uptake YP_002272474.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_002272475.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_002272476.1 involved in hydrogen uptake YP_002272477.1 identified by glimmer YP_002272479.1 identified by match to protein family HMM PF01738 YP_002272480.1 identified by match to protein family HMM PF00248 YP_002272481.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645 YP_002272482.1 identified by match to protein family HMM PF00106 YP_002272483.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002272484.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002272485.1 catalyzes the formation of L-homocysteine from cystathionine YP_002272486.1 identified by match to protein family HMM PF09335 YP_002272487.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06719 YP_002272488.1 identified by glimmer YP_002272489.1 identified by match to protein family HMM PF00465 YP_002272490.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_002272492.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497 YP_002272493.1 identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409 YP_002272494.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002272495.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002272496.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system YP_002272497.1 identified by match to protein family HMM PF06445 YP_002272498.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_002272499.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_002272500.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002272501.1 identified by match to protein family HMM PF02525 YP_002272502.1 identified by match to protein family HMM PF03992 YP_002272503.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002272504.1 identified by match to protein family HMM PF01497 YP_002272505.1 identified by match to protein family HMM PF01032 YP_002272506.1 identified by match to protein family HMM PF01032 YP_002272507.1 identified by match to protein family HMM PF00005 YP_002272508.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_002272509.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002272510.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002272511.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413 YP_002272512.1 identified by match to protein family HMM PF06853 YP_002272513.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002272514.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002272516.1 identified by match to protein family HMM PF03738 YP_002272517.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_002272518.1 identified by match to protein family HMM PF02535 YP_002272520.1 DHBP synthase; functions during riboflavin biosynthesis YP_002272521.1 identified by match to protein family HMM PF04380 YP_002272522.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_002272523.1 identified by match to protein family HMM PF01145 YP_002272524.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_002272525.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002272526.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235 YP_002272527.1 identified by glimmer YP_002272529.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_002272530.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002272531.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_002272532.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002272533.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol YP_002272534.1 Involved in the tartrate degradation pathway YP_002272535.1 Involved in the tartrate degradation pathway YP_002272536.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_002272537.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002272538.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002272539.1 synthesizes RNA primers at the replication forks YP_002272540.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002272541.1 identified by match to protein family HMM PF03167 YP_002272542.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021 YP_002272543.1 identified by match to protein family HMM PF03551 YP_002272544.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229 YP_002272545.1 identified by glimmer YP_002272546.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_002272547.1 identified by match to protein family HMM PF01588 YP_002272548.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002272549.1 in Escherichia coli this is the second beta-galactosidase system YP_002272550.1 in Escherichia coli this is the second beta-galactosidase system YP_002272551.1 identified by match to protein family HMM PF00324 YP_002272554.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_002272555.1 identified by match to protein family HMM PF01381 YP_002272557.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_002272558.1 identified by match to protein family HMM PF01863 YP_002272559.1 identified by match to protein family HMM PF02698 YP_002272560.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002272561.1 identified by match to protein family HMM PF03741 YP_002272562.1 involved in the import of serine and threonine coupled with the import of sodium YP_002272564.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666 YP_002272565.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_002272566.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_002272567.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_002272568.1 identified by match to protein family HMM PF09335 YP_002272570.1 identified by match to protein family HMM PF06476 YP_002272571.1 identified by match to protein family HMM PF05957 YP_002272574.1 identified by match to protein family HMM PF07681 YP_002272576.1 identified by match to protein family HMM PF05656 YP_002272577.1 identified by match to protein family HMM PF05656 YP_002272578.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002272579.1 identified by match to protein family HMM PF02678 YP_002272581.1 identified by match to protein family HMM PF06354 YP_002272582.1 identified by match to protein family HMM TIGR00814 YP_002272583.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002272584.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002272585.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002272586.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_002272587.1 involved in the import of threonine and serine in combination with the import of a proton YP_002272588.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_002272589.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_002272590.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon YP_002272591.1 identified by glimmer YP_002272593.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002272594.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_002272595.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_002272596.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_002272597.1 identified by glimmer YP_002272598.1 identified by glimmer YP_002272599.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248 YP_002272602.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_002272603.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_002272604.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport YP_002272605.1 identified by match to protein family HMM PF03609 YP_002272606.1 identified by match to protein family HMM PF03613 YP_002272607.1 identified by match to protein family HMM PF03610 YP_002272608.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_002272609.1 identified by glimmer YP_002272610.1 identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815 YP_002272611.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_002272612.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_002272613.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_002272614.1 identified by match to protein family HMM PF00419 YP_002272615.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002272616.1 identified by match to protein family HMM PF00577 YP_002272617.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002272618.1 identified by match to protein family HMM PF04348 YP_002272619.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_002272620.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_002272621.1 identified by match to protein family HMM PF04972 YP_002272622.1 identified by match to protein family HMM PF03773 YP_002272623.1 identified by match to protein family HMM PF01370 YP_002272624.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_002272626.1 identified by match to protein family HMM PF01541 YP_002272627.1 identified by match to protein family HMM PF00583 YP_002272628.1 identified by match to protein family HMM PF02036 YP_002272629.1 identified by match to protein family HMM PF01136 YP_002272630.1 identified by match to protein family HMM PF01136 YP_002272631.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558 YP_002272632.1 tryptophan transporter of high affinity YP_002272633.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_002272634.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002272635.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR03591 YP_002272636.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002272637.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002272638.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002272639.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002272640.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002272641.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002272643.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_002272644.1 identified by match to protein family HMM PF00884 YP_002272645.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002272646.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002272647.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_002272648.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_002272649.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002272650.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability YP_002272651.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002272652.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002272653.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002272654.1 identified by match to protein family HMM PF00892 YP_002272655.1 involved in the peptidyltransferase reaction during translation YP_002272656.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002272657.1 identified by match to protein family HMM PF00348 YP_002272658.1 activator of maltose metabolism genes YP_002272659.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002272660.1 identified by match to protein family HMM PF01722 YP_002272662.1 identified by match to protein family HMM PF05494 YP_002272663.1 identified by match to protein family HMM PF02470 YP_002272664.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056 YP_002272665.1 ATP-binding subunit of a ABC toluene efflux transporter YP_002272666.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_002272667.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_002272668.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002272669.1 identified by match to protein family HMM PF06835 YP_002272670.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_002272671.1 identified by match to protein family HMM PF00005 YP_002272672.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002272673.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_002272674.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419 YP_002272675.1 identified by match to protein family HMM PF03668 YP_002272676.1 identified by match to protein family HMM PF00381 YP_002272678.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002272679.1 identified by match to protein family HMM PF01965 YP_002272680.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002272681.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_002272682.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_002272683.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_002272684.1 identified by match to protein family HMM PF06250 YP_002272685.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002272686.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_002272687.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002272688.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891 YP_002272689.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_002272690.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_002272691.1 identified by match to protein family HMM PF04386 YP_002272692.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002272693.1 forms a direct contact with the tRNA during translation YP_002272694.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002272695.1 identified by match to protein family HMM PF03969 YP_002272696.1 identified by match to protein family HMM PF06295 YP_002272697.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037 YP_002272698.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038 YP_002272699.1 oxidizes malate to oxaloacetate YP_002272700.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002272701.1 identified by match to protein family HMM PF07338 YP_002272703.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002272704.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002272705.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_002272706.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002272707.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_002272708.1 identified by match to protein family HMM TIGR02099 YP_002272709.1 involved in the processing of the 5'end of 16S rRNA YP_002272710.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002272711.1 part of cell wall structural complex MreBCD; transmembrane component YP_002272712.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002272713.1 functions in MreBCD complex in some organisms YP_002272714.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002272715.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_002272717.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002272718.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002272719.1 identified by match to protein family HMM PF06196 YP_002272720.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002272721.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002272722.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002272723.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002272724.1 identified by match to protein family HMM PF01555 YP_002272726.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08361 YP_002272727.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002272729.1 identified by glimmer YP_002272731.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002272732.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002272733.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527 YP_002272734.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665 YP_002272735.1 identified by match to protein family HMM PF00005 YP_002272737.1 identified by match to protein family HMM PF07369 YP_002272738.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002272739.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_002272740.1 identified by match to protein family HMM PF01396 YP_002272741.1 identified by match to protein family HMM PF04361 YP_002272742.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002272743.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002272744.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002272745.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_002272746.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002272747.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002272748.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_002272749.1 identified by match to protein family HMM PF09350 YP_002272750.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002272751.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002272752.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002272753.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002272754.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002272755.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002272756.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002272757.1 late assembly protein YP_002272758.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002272759.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002272760.1 binds 5S rRNA along with protein L5 and L25 YP_002272761.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002272762.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002272763.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002272764.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002272765.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002272766.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002272767.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002272768.1 one of the stabilizing components for the large ribosomal subunit YP_002272769.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002272770.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002272771.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002272772.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002272773.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002272774.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002272775.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002272776.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002272777.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002272779.1 iron storage protein YP_002272780.1 identified by match to protein family HMM PF04324 YP_002272781.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002272782.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002272783.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002272784.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002272785.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002272786.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002272787.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002272788.1 identified by match to protein family HMM PF08348 YP_002272789.1 rotamase YP_002272790.1 identified by match to protein family HMM PF04102 YP_002272791.1 rotamase YP_002272792.1 identified by match to protein family HMM PF09526; match to protein family HMM TIGR02443 YP_002272793.1 required for KefB activity YP_002272794.1 identified by match to protein family HMM PF00005 YP_002272795.1 identified by match to protein family HMM PF00561 YP_002272796.1 identified by match to protein family HMM PF06794 YP_002272797.1 identified by match to protein family HMM PF00485 YP_002272798.1 identified by match to protein family HMM PF02566 YP_002272799.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002272800.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667 YP_002272801.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_002272802.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_002272803.1 identified by match to protein family HMM PF02661 YP_002272805.1 identified by match to protein family HMM PF00160 YP_002272806.1 identified by glimmer YP_002272807.1 identified by match to protein family HMM PF07690 YP_002272808.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_002272809.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_002272810.1 member of the FNT family of formate and nitrite transporters YP_002272811.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_002272813.1 identified by glimmer YP_002272814.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon YP_002272815.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine YP_002272816.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine YP_002272817.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes YP_002272818.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002272819.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002272820.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002272821.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_002272822.1 identified by match to protein family HMM PF05036 YP_002272823.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002272824.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002272825.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_002272828.1 identified by glimmer YP_002272829.1 identified by match to protein family HMM PF05137 YP_002272830.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_002272831.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002272832.1 identified by match to protein family HMM PF07095 YP_002272833.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002272834.1 identified by match to protein family HMM PF01479 YP_002272835.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002272837.1 identified by glimmer YP_002272838.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002272839.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002272840.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002272841.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002272842.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371 YP_002272844.1 identified by match to protein family HMM PF04023 YP_002272845.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_002272846.1 identified by match to protein family HMM PF09012 YP_002272847.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002272848.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_002272849.1 involved in high-affinity gluconate transport YP_002272850.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002272851.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002272852.1 amylomaltase; acts to release glucose from maltodextrins YP_002272853.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002272854.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_002272855.1 identified by match to protein family HMM PF08681 YP_002272856.1 identified by match to protein family HMM PF00583 YP_002272857.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_002272858.1 identified by match to protein family HMM PF01139 YP_002272859.1 identified by match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728 YP_002272860.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_002272861.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_002272862.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_002272863.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002272868.1 identified by glimmer YP_002272869.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002272870.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002272871.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002272872.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_002272873.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002272874.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002272875.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_002272877.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002272878.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_002272879.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002272880.1 identified by glimmer YP_002272881.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_002272882.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002272883.1 YhhY; regulated by the fur regulator; unknown function YP_002272885.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_002272887.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002272888.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_002272889.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_002272890.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_002272891.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_002272892.1 identified by glimmer YP_002272894.1 identified by glimmer YP_002272895.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002272896.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002272897.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002272898.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_002272899.1 identified by match to protein family HMM PF01094 YP_002272900.1 identified by glimmer YP_002272901.1 identified by match to protein family HMM PF00583 YP_002272903.1 identified by match to protein family HMM PF08681 YP_002272904.1 identified by match to protein family HMM PF01094 YP_002272905.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002272906.1 ABC transporter membrane protein YP_002272907.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_002272908.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_002272909.1 catalyzes the methylation of 16S rRNA at position G966 YP_002272910.1 identified by match to protein family HMM PF06611 YP_002272912.1 identified by match to protein family HMM PF07947 YP_002272913.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_002272914.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_002272915.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697 YP_002272917.1 identified by match to protein family HMM PF07690 YP_002272918.1 identified by match to protein family HMM PF01594 YP_002272920.1 identified by match to protein family HMM PF00891; match to protein family HMM PF08242 YP_002272923.1 carries the fatty acid chain in fatty acid biosynthesis YP_002272926.1 identified by match to protein family HMM PF00535 YP_002272927.1 identified by match to protein family HMM PF03061 YP_002272928.1 identified by match to protein family HMM PF03548 YP_002272931.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002272932.1 identified by match to protein family HMM PF07977 YP_002272933.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002272934.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002272935.1 identified by match to protein family HMM PF01648 YP_002272936.1 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294 YP_002272937.1 with NikACDE is involved in nickel transport into the cell YP_002272938.1 with NikABDE is involved in nickel transport into the cell YP_002272939.1 with NikABCE is involved in nickel transport into the cell YP_002272940.1 with NikABCD is involved with nickel transport into the cell YP_002272941.1 Inhibits transcription at high concentrations of nickel YP_002272942.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002272943.1 identified by match to protein family HMM PF00359 YP_002272944.1 identified by match to protein family HMM PF02302 YP_002272945.1 identified by match to protein family HMM PF03611 YP_002272946.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002272947.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002272948.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_002272949.1 identified by match to protein family HMM PF05534 YP_002272950.1 identified by match to protein family HMM PF01061 YP_002272951.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061 YP_002272952.1 identified by match to protein family HMM PF00529 YP_002272957.1 identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_002272958.1 identified by match to protein family HMM PF01384 YP_002272959.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002272960.1 identified by match to protein family HMM PF00582 YP_002272962.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_002272963.1 predicted SAM-dependent methyltransferase YP_002272964.1 identified by match to protein family HMM PF01432 YP_002272965.1 identified by match to protein family HMM PF04378 YP_002272966.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002272967.1 identified by glimmer YP_002272968.1 identified by glimmer YP_002272969.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_002272970.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935 YP_002272971.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_002272972.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_002272973.1 identified by match to protein family HMM PF00196 YP_002272974.1 identified by match to protein family HMM PF05171 YP_002272975.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01785; match to protein family HMM TIGR01786 YP_002272978.1 identified by match to protein family HMM PF01497 YP_002272979.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002272980.1 identified by match to protein family HMM PF06228 YP_002272982.1 identified by match to protein family HMM PF01032 YP_002272983.1 with HmuTU is involved in the transport of hemin YP_002272984.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_002272986.1 inactive form YP_002272989.1 identified by glimmer YP_002272990.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds YP_002272991.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002272992.1 identified by match to protein family HMM PF00165 YP_002272993.1 regulates genes in response to acid and/or during stationary phase YP_002272994.1 identified by glimmer YP_002272995.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_002272996.1 identified by match to protein family HMM PF03150 YP_002272997.1 identified by glimmer YP_002272998.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_002272999.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002273000.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002273001.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766 YP_002273002.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002273003.1 identified by match to protein family HMM PF05170 YP_002273004.1 in Escherichia coli this protein is involved in flagellar function YP_002273005.1 identified by glimmer YP_002273006.1 identified by match to protein family HMM PF00294 YP_002273007.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002273008.1 involved in the transport of C4-dicarboxylates across the membrane YP_002273009.1 identified by glimmer YP_002273010.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli YP_002273011.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_002273012.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_002273013.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_002273014.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_002273016.1 identified by match to protein family HMM TIGR03369 YP_002273017.1 identified by match to protein family HMM TIGR03493 YP_002273018.1 identified by match to protein family HMM TIGR03368 YP_002273020.1 identified by glimmer YP_002273021.1 identified by match to protein family HMM TIGR00814 YP_002273022.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002273023.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_002273024.1 identified by match to protein family HMM PF00528 YP_002273025.1 transports peptides consisting of two or three amino acids YP_002273026.1 identified by glimmer YP_002273027.1 identified by match to protein family HMM PF00496 YP_002273028.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_002273029.1 identified by match to protein family HMM PF00419 YP_002273030.1 identified by match to protein family HMM PF00419 YP_002273031.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002273032.1 identified by match to protein family HMM PF00419 YP_002273033.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890 YP_002273035.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine YP_002273036.1 identified by match to protein family HMM PF00583 YP_002273037.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509 YP_002273038.1 identified by match to protein family HMM PF00691; match to protein family HMM PF05433 YP_002273039.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002273042.1 identified by match to protein family HMM PF00313 YP_002273043.1 identified by match to protein family HMM PF01848 YP_002273044.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002273045.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002273048.1 identified by match to protein family HMM PF05360 YP_002273049.1 identified by match to protein family HMM PF05360 YP_002273050.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312 YP_002273051.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002273052.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_002273053.1 with XylFH is part of the high affinity xylose ABC transporter YP_002273054.1 identified by match to protein family HMM PF02653 YP_002273055.1 identified by match to protein family HMM PF00165 YP_002273056.1 identified by match to protein family HMM PF01832 YP_002273057.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_002273058.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_002273059.1 identified by match to protein family HMM PF00037 YP_002273060.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311 YP_002273061.1 identified by match to protein family HMM TIGR00792 YP_002273062.1 identified by match to protein family HMM PF07944 YP_002273063.1 identified by match to protein family HMM PF06629 YP_002273064.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002273065.1 identified by match to protein family HMM PF00529 YP_002273067.1 identified by match to protein family HMM PF00171 YP_002273068.1 identified by match to protein family HMM PF02661 YP_002273069.1 identified by match to protein family HMM PF00465 YP_002273070.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475 YP_002273071.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_002273072.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002273073.1 identified by glimmer YP_002273074.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002273076.1 identified by match to protein family HMM PF00529 YP_002273078.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_002273079.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002273080.1 Acts as a repressor of the mtlAD operon YP_002273084.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662 YP_002273085.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002273086.1 represses the lctPRD operon YP_002273087.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_002273088.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_002273089.1 catalyzes the O-acetylation of serine YP_002273090.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002273091.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002273092.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02181 YP_002273093.1 identified by match to protein family HMM PF00581 YP_002273094.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002273095.1 identified by match to protein family HMM PF01551 YP_002273096.1 identified by match to protein family HMM PF04748 YP_002273097.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_002273098.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002273099.1 identified by match to protein family HMM PF09612; match to protein family HMM TIGR02192 YP_002273100.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002273101.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_002273102.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193 YP_002273103.1 identified by match to protein family HMM PF04932 YP_002273104.1 identified by match to protein family HMM PF00534 YP_002273105.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_002273106.1 identified by match to protein family HMM PF06176 YP_002273107.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_002273108.1 identified by match to protein family HMM PF06293 YP_002273109.1 identified by match to protein family HMM PF00534 YP_002273110.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02201 YP_002273111.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002273112.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002273113.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002273114.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002273115.1 required for 70S ribosome assembly YP_002273116.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002273117.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_002273118.1 catalyzes the formation of dUMP from dUTP YP_002273119.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002273120.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002273121.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002273122.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_002273123.1 identified by glimmer YP_002273125.1 identified by match to protein family HMM PF03458 YP_002273126.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_002273128.1 Essential for recycling GMP and indirectly, cGMP YP_002273129.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002273130.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002273131.1 specifically modifies tRNA at position G18 YP_002273132.1 catalyzes branch migration in Holliday junction intermediates YP_002273134.1 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210 YP_002273135.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002273136.1 identified by match to protein family HMM PF05170 YP_002273137.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_002273138.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_002273139.1 identified by match to protein family HMM PF00589 YP_002273140.1 identified by match to protein family HMM PF01527 YP_002273141.1 identified by match to protein family HMM PF00665 YP_002273143.1 identified by match to protein family HMM PF06755 YP_002273146.1 identified by match to protein family HMM PF05717 YP_002273147.1 identified by match to protein family HMM PF03050 YP_002273148.1 identified by glimmer YP_002273149.1 identified by match to protein family HMM PF04806 YP_002273150.1 identified by glimmer YP_002273151.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105 YP_002273153.1 identified by match to protein family HMM PF05802 YP_002273154.1 identified by match to protein family HMM PF04888 YP_002273155.1 identified by match to protein family HMM PF03433 YP_002273156.1 identified by match to protein family HMM PF07018; match to protein family HMM TIGR02511 YP_002273157.1 identified by match to protein family HMM TIGR02500 YP_002273158.1 identified by match to protein family HMM PF01476; match to protein family HMM PF02368; match to protein family HMM PF02369; match to protein family HMM PF07979 YP_002273159.1 identified by match to protein family HMM PF05932 YP_002273160.1 identified by match to protein family HMM PF03549; match to protein family HMM PF07489; match to protein family HMM PF07490 YP_002273161.1 identified by match to protein family HMM PF03278 YP_002273166.1 identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546 YP_002273167.1 identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399 YP_002273169.1 identified by glimmer YP_002273170.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_002273171.1 identified by glimmer YP_002273173.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516 YP_002273175.1 identified by match to protein family HMM PF01464 YP_002273176.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli YP_002273177.1 identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_002273179.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_002273183.1 identified by match to protein family HMM TIGR02501 YP_002273184.1 identified by match to protein family HMM PF00816 YP_002273185.1 identified by match to protein family HMM PF06872 YP_002273186.1 identified by match to protein family HMM PF06977 YP_002273187.1 identified by glimmer YP_002273189.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_002273190.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_002273193.1 identified by match to protein family HMM PF06296 YP_002273194.1 identified by match to protein family HMM PF01381 YP_002273195.1 identified by match to protein family HMM PF06711 YP_002273196.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_002273197.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_002273198.1 membrane protein regulates uhpT expression YP_002273199.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_002273200.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_002273201.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_002273202.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_002273203.1 multidrug efflux protein involved in adaptation to low energy shock YP_002273206.1 identified by match to protein family HMM PF02656 YP_002273208.1 identified by match to protein family HMM PF00884 YP_002273209.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function YP_002273210.1 identified by match to protein family HMM PF00165 YP_002273211.1 identified by match to protein family HMM PF02056 YP_002273212.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005 YP_002273213.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002273214.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_002273215.1 identified by glimmer YP_002273216.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_002273217.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_002273219.1 identified by match to protein family HMM PF07119 YP_002273221.1 FAD/NAD(P)-binding domain YP_002273222.1 identified by glimmer YP_002273223.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_002273224.1 identified by match to protein family HMM PF06078 YP_002273225.1 negatively supercoils closed circular double-stranded DNA YP_002273226.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002273227.1 binds the polymerase to DNA and acts as a sliding clamp YP_002273228.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002273229.1 identified by glimmer YP_002273230.1 identified by glimmer YP_002273231.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002273232.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002273233.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002273234.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002273235.1 identified by match to protein family HMM PF07906 YP_002273236.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_002273237.1 tryptophan transporter of low affinity YP_002273238.1 Confers resistance to chloramphenicol YP_002273239.1 Involved in anaerobic NO protection YP_002273241.1 identified by match to protein family HMM PF03358 YP_002273242.1 identified by match to protein family HMM PF00860 YP_002273243.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_002273244.1 identified by glimmer YP_002273247.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002273248.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002273249.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002273250.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002273251.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975 YP_002273252.1 identified by glimmer YP_002273253.1 identified by match to protein family HMM PF00419 YP_002273255.1 identified by match to protein family HMM PF00577 YP_002273256.1 identified by match to protein family HMM PF00419 YP_002273257.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002273258.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002273259.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002273260.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002273261.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002273262.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002273263.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002273264.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002273265.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002273266.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002273267.1 identified by match to protein family HMM PF03899 YP_002273268.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002273269.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002273270.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002273271.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002273272.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002273273.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002273274.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_002273275.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002273276.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002273277.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_002273278.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002273279.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_002273280.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002273281.1 DNA-binding transcriptional repressor of ribose metabolism YP_002273282.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002273283.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002273284.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_002273285.1 identified by match to protein family HMM PF04219 YP_002273286.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function YP_002273287.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002273289.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002273290.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002273291.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_002273292.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002273293.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002273294.1 identified by match to protein family HMM PF00639 YP_002273296.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_002273297.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_002273298.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_002273299.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002273300.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002273301.1 identified by glimmer YP_002273302.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380 YP_002273303.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_002273304.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002273305.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_002273306.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_002273307.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_002273308.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382 YP_002273309.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002273310.1 identified by match to protein family HMM PF01943 YP_002273311.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_002273312.1 enterobacterial common antigen polymerase YP_002273313.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002273314.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_002273315.1 identified by match to protein family HMM PF04055 YP_002273316.1 identified by match to protein family HMM PF00884 YP_002273317.1 identified by glimmer YP_002273318.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540 YP_002273319.1 identified by match to protein family HMM PF04375 YP_002273320.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002273321.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002273322.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002273323.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_002273326.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002273327.1 identified by match to protein family HMM PF04340 YP_002273328.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002273329.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_002273330.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002273331.1 identified by match to protein family HMM PF01887 YP_002273333.1 identified by glimmer YP_002273334.1 responsible for the influx of magnesium ions YP_002273335.1 identified by match to protein family HMM PF06092 YP_002273336.1 identified by match to protein family HMM TIGR03034 YP_002273337.1 identified by glimmer YP_002273338.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002273339.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002273340.1 catalyzes the hydrolysis of phosphatidylcholine YP_002273341.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_002273342.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002273343.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002273344.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_002273345.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_002273347.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002273348.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002273349.1 identified by match to protein family HMM PF01738 YP_002273350.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002273351.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_002273352.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002273353.1 identified by match to protein family HMM PF02036 YP_002273354.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002273355.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002273356.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_002273357.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_002273358.1 magnesium dependent; not involved in the Sec-independent protein export system YP_002273359.1 identified by match to protein family HMM PF02357; match to protein family HMM TIGR01955 YP_002273360.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_002273361.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002273362.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002273363.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002273364.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_002273365.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002273366.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002273367.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_002273368.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_002273369.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002273370.1 identified by match to protein family HMM PF06288 YP_002273371.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_002273372.1 identified by match to protein family HMM PF01323 YP_002273373.1 identified by glimmer YP_002273374.1 identified by match to protein family HMM PF06097 YP_002273375.1 identified by match to protein family HMM PF01553 YP_002273376.1 identified by glimmer YP_002273377.1 identified by glimmer YP_002273378.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002273379.1 identified by glimmer YP_002273380.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002273381.1 identified by match to protein family HMM PF04220 YP_002273382.1 identified by glimmer YP_002273383.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002273384.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_002273385.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_002273386.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002273387.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002273388.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002273389.1 identified by match to protein family HMM PF01261 YP_002273390.1 identified by match to protein family HMM PF07690 YP_002273391.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown YP_002273392.1 identified by match to protein family HMM TIGR00792 YP_002273393.1 identified by match to protein family HMM TIGR00792 YP_002273394.1 identified by match to protein family HMM PF01055 YP_002273395.1 identified by match to protein family HMM PF01925 YP_002273396.1 identified by match to protein family HMM PF01263 YP_002273397.1 identified by match to protein family HMM PF07221 YP_002273398.1 identified by match to protein family HMM PF01791 YP_002273399.1 identified by match to protein family HMM PF03446 YP_002273400.1 identified by match to protein family HMM PF00294 YP_002273401.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002273402.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002273403.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_002273404.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002273405.1 identified by match to protein family HMM PF00583; match to protein family HMM PF09500; match to protein family HMM TIGR02447 YP_002273406.1 identified by match to protein family HMM PF01402 YP_002273408.1 required for the formation of active formate dehydrogenase YP_002273409.1 cytochrome b556(FDO) component; heme containing YP_002273410.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_002273411.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002273413.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system YP_002273414.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars YP_002273415.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427 YP_002273416.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system YP_002273418.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625 YP_002273419.1 identified by match to protein family HMM PF00596; match to protein family HMM TIGR02624 YP_002273420.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_002273421.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_002273422.1 identified by glimmer YP_002273423.1 activates the expression of the rhaBAD operon and rhaT gene YP_002273424.1 activates the expression of rhaRS in response to L-rhamnose YP_002273425.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_002273427.1 transports degraded pectin products into the bacterial cell YP_002273428.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002273429.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002273430.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_002273431.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_002273432.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_002273433.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002273435.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_002273436.1 identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672 YP_002273437.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002273438.1 identified by match to protein family HMM PF07305 YP_002273439.1 identified by match to protein family HMM PF05656 YP_002273440.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_002273441.1 with UspC and Usp E is involved in resistance to UV radiation YP_002273442.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002273443.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002273444.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002273445.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002273446.1 identified by match to protein family HMM PF06005 YP_002273447.1 identified by glimmer YP_002273448.1 identified by glimmer YP_002273449.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002273450.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002273451.1 heat shock protein involved in degradation of misfolded proteins YP_002273452.1 heat shock protein involved in degradation of misfolded proteins YP_002273453.1 identified by match to protein family HMM PF05036; match to protein family HMM TIGR02223 YP_002273454.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_002273455.1 identified by glimmer YP_002273456.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002273457.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002273458.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002273459.1 member of the NlpC/P60 superfamily of peptidases YP_002273460.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002273461.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002273462.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002273463.1 identified by glimmer YP_002273464.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_002273465.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_002273466.1 identified by match to protein family HMM PF00892 YP_002273467.1 identified by match to protein family HMM PF06940 YP_002273468.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002273469.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002273470.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_002273471.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_002273472.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_002273473.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_002273474.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002273475.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_002273476.1 identified by match to protein family HMM PF00165 YP_002273477.1 identified by match to protein family HMM PF00884 YP_002273478.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002273479.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002273480.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002273481.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002273482.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002273483.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_002273484.1 catalyzes the conversion of NADPH to NADH YP_002273485.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002273486.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002273487.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_002273488.1 identified by match to protein family HMM PF07226 YP_002273489.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002273490.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_002273491.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002273492.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002273493.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002273494.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002273496.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002273497.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002273498.1 Modulates Rho-dependent transcription termination YP_002273499.1 binds directly to 23S ribosomal RNA YP_002273500.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002273501.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002273502.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002273503.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002273504.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002273505.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_002273506.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002273507.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_002273508.1 identified by match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356 YP_002273509.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_002273510.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002273511.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_002273512.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_002273513.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002273514.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_002273515.1 identified by match to protein family HMM PF04222 YP_002273516.1 histone-like DNA-binding protein YP_002273517.1 identified by match to protein family HMM PF07356 YP_002273519.1 identified by glimmer YP_002273520.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002273521.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_002273522.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002273523.1 involved in de novo purine biosynthesis YP_002273524.1 identified by match to protein family HMM PF00583 YP_002273525.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002273526.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002273527.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_002273528.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_002273529.1 identified by match to protein family HMM PF07906 YP_002273530.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_002273531.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_002273532.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013 YP_002273533.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_002273534.1 identified by glimmer YP_002273535.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002273536.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828 YP_002273537.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_002273538.1 identified by match to protein family HMM PF03610; match to protein family HMM TIGR00824 YP_002273539.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate YP_002273540.1 identified by match to protein family HMM PF04198 YP_002273541.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_002273543.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_002273544.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002273545.1 identified by glimmer YP_002273547.1 identified by match to protein family HMM PF06251 YP_002273548.1 identified by match to protein family HMM PF06082 YP_002273550.1 identified by glimmer YP_002273551.1 identified by match to protein family HMM PF06146 YP_002273552.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter YP_002273553.1 with MalKFE is involved in the transport of maltose into the cell YP_002273554.1 with MalKGE is involved in maltose transport into the cell YP_002273555.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_002273556.1 with malEFG is involved in import of maltose/maltodextrin YP_002273557.1 porin involved in the transport of maltose and maltodextrins YP_002273558.1 identified by match to protein family HMM PF07148 YP_002273559.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations YP_002273560.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_002273561.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_002273562.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002273563.1 identified by match to protein family HMM PF01219 YP_002273564.1 Represses a number of genes involved in the response to DNA damage YP_002273565.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002273566.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_002273567.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_002273579.1 identified by match to protein family HMM PF06316 YP_002273582.1 identified by match to protein family HMM PF06820 YP_002273583.1 identified by match to protein family HMM PF06820 YP_002273584.1 identified by match to protein family HMM PF06416 YP_002273585.1 identified by match to protein family HMM PF06416 YP_002273586.1 identified by match to protein family HMM PF06416 YP_002273587.1 identified by match to protein family HMM PF06183 YP_002273588.1 identified by match to protein family HMM PF00589 YP_002273589.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00742 YP_002273590.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_002273591.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002273592.1 unwinds double stranded DNA YP_002273593.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002273594.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002273595.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_002273596.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149 YP_002273597.1 identified by match to protein family HMM PF04237 YP_002273598.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002273599.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_002273601.1 identified by match to protein family HMM PF00563 YP_002273602.1 regulates genes involved in response to oxidative stress YP_002273603.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950 YP_002273604.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002273605.1 identified by glimmer YP_002273606.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831 YP_002273607.1 identified by match to protein family HMM PF00805 YP_002273608.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_002273609.1 identified by match to protein family HMM PF04341 YP_002273610.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002273611.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_002273612.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_002273613.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149 YP_002273614.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148 YP_002273615.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_002273616.1 identified by match to protein family HMM PF03918; match to protein family HMM TIGR03147 YP_002273617.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002273618.1 identified by glimmer YP_002273619.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_002273620.1 identified by match to protein family HMM PF08238 YP_002273621.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_002273622.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002273623.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002273625.1 identified by glimmer YP_002273626.1 identified by match to protein family HMM PF00753 YP_002273627.1 identified by glimmer YP_002273628.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002273629.1 identified by match to protein family HMM PF00294 YP_002273630.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167 YP_002273631.1 identified by match to protein family HMM PF07385 YP_002273632.1 identified by match to protein family HMM PF00532 YP_002273633.1 identified by match to protein family HMM PF02653 YP_002273634.1 identified by match to protein family HMM PF00005 YP_002273635.1 identified by glimmer YP_002273636.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002273637.1 required for the use of phosphonates and phosphite as phosphorus sources YP_002273638.1 identified by match to protein family HMM TIGR02322 YP_002273639.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318 YP_002273640.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02324 YP_002273641.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323 YP_002273642.1 identified by match to protein family HMM PF06007 YP_002273643.1 identified by match to protein family HMM PF05861 YP_002273644.1 identified by match to protein family HMM PF05845; match to protein family HMM TIGR03292 YP_002273645.1 identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293 YP_002273646.1 may be involved in phosphonate uptake and biodegradation YP_002273647.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_002273648.1 identified by glimmer YP_002273649.1 identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431 YP_002273650.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315 YP_002273651.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983 YP_002273652.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002273655.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883 YP_002273656.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002273657.1 response regulator in two-component regulatory system with BasS YP_002273658.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_002273659.1 identified by match to protein family HMM PF00324 YP_002273660.1 identified by match to protein family HMM PF00165 YP_002273661.1 identified by glimmer YP_002273662.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002273663.1 identified by match to protein family HMM PF00165 YP_002273664.1 identified by match to protein family HMM PF02056 YP_002273665.1 identified by match to protein family HMM TIGR00792 YP_002273667.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002273668.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_002273669.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_002273670.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002273671.1 identified by glimmer YP_002273672.1 identified by match to protein family HMM PF06902 YP_002273674.1 identified by glimmer YP_002273676.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002273677.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002273678.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002273679.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_002273680.1 regulates the cadBA operon YP_002273681.1 identified by match to protein family HMM PF00440 YP_002273682.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002273683.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_002273684.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002273685.1 catalyzes the formation of fumarate from aspartate YP_002273686.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_002273687.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002273688.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002273691.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_002273692.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002273693.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex YP_002273694.1 identified by match to protein family HMM PF08085 YP_002273695.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_002273696.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_002273697.1 identified by match to protein family HMM PF00144 YP_002273698.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_002273699.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002273700.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002273701.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002273702.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002273703.1 identified by match to protein family HMM PF00324 YP_002273704.1 identified by match to protein family HMM PF00924 YP_002273705.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002273706.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002273707.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_002273708.1 identified by match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_002273709.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_002273710.1 possibly involved in cell wall synthesis YP_002273711.1 identified by match to protein family HMM PF01520 YP_002273712.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002273713.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002273714.1 Stimulates the elongation of poly(A) tails YP_002273715.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002273716.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_002273717.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_002273719.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002273720.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_002273721.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_002273722.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002273724.1 identified by match to protein family HMM PF04012 YP_002273726.1 identified by match to protein family HMM PF03994 YP_002273727.1 identified by match to protein family HMM PF06693 YP_002273728.1 identified by match to protein family HMM PF03738 YP_002273729.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_002273730.1 identified by match to protein family HMM PF07338 YP_002273731.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_002273732.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_002273733.1 negative regulator of ulaG and ulaABCDEF YP_002273735.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002273736.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002273737.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002273738.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002273739.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_002273740.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002273741.1 identified by match to protein family HMM PF07338 YP_002273742.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002273743.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002273744.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002273747.1 identified by glimmer YP_002273748.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002273749.1 identified by match to protein family HMM PF04225; match to protein family HMM PF08525 YP_002273750.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_002273751.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_002273752.1 Involved in anaerobic NO protection and iron metabolism YP_002273753.1 identified by match to protein family HMM PF00892 YP_002273754.1 identified by match to protein family HMM PF01073; match to protein family HMM PF02254; match to protein family HMM PF05368 YP_002273755.1 identified by match to protein family HMM PF01638 YP_002273756.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_002273757.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_002273759.1 identified by match to protein family HMM PF09695; match to protein family HMM TIGR01626 YP_002273760.1 identified by match to protein family HMM PF06526 YP_002273761.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002273762.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_002273763.1 identified by glimmer YP_002273764.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244 YP_002273765.1 identified by match to protein family HMM PF04357 YP_002273766.1 identified by match to protein family HMM PF06094 YP_002273767.1 part of the toxin-antitoxin ChpB-ChpS system YP_002273768.1 toxin of the ChpB-ChpS toxin-antitoxin system YP_002273769.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002273770.1 identified by glimmer YP_002273771.1 identified by match to protein family HMM PF00532 YP_002273772.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF02653 YP_002273773.1 membrane component of a sugar ABC transporter system YP_002273774.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_002273775.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081 YP_002273776.1 identified by match to protein family HMM PF04751 YP_002273777.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002273778.1 identified by match to protein family HMM PF07361 YP_002273779.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_002273781.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002273782.1 identified by glimmer YP_002273783.1 identified by glimmer YP_002273784.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002273785.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002273786.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_002273787.1 P-type ATPase involved in magnesium influx YP_002273788.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002273789.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002273790.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002273791.1 identified by glimmer YP_002273792.1 identified by match to protein family HMM PF01042 YP_002273793.1 identified by glimmer YP_002273794.1 identified by match to protein family HMM PF00106 YP_002273795.1 identified by match to protein family HMM PF00440 YP_002273796.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002273798.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_002273799.1 identified by match to protein family HMM PF06877 YP_002273800.1 identified by match to protein family HMM PF00583 YP_002273801.1 identified by match to protein family HMM PF05987 YP_002273802.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002273803.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002273804.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002273805.1 identified by glimmer YP_002273806.1 identified by match to protein family HMM PF03739 YP_002273807.1 identified by match to protein family HMM PF03739 YP_002273808.1 identified by match to protein family HMM PF05872 YP_002273809.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002273811.1 identified by match to protein family HMM PF00589 YP_002273812.1 identified by match to protein family HMM PF07978 YP_002273813.1 identified by match to protein family HMM PF07799 YP_002273814.1 identified by match to protein family HMM PF00239 YP_002273817.1 identified by match to protein family HMM PF01381 YP_002273818.1 identified by glimmer YP_002273824.1 identified by glimmer YP_002273825.1 identified by glimmer YP_002273826.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369 YP_002273827.1 identified by glimmer YP_002273828.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_002273829.1 identified by glimmer YP_002273830.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369 YP_002273831.1 identified by match to protein family HMM PF00580 YP_002273832.1 identified by match to protein family HMM PF03629 YP_002273833.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646; match to protein family HMM TIGR03547 YP_002273834.1 identified by match to protein family HMM PF06178 YP_002273835.1 identified by glimmer YP_002273836.1 identified by glimmer YP_002273837.1 inversion of on/off regulator of fimA YP_002273838.1 inversion of on/off regulator of fimA YP_002273839.1 identified by match to protein family HMM PF00419 YP_002273840.1 identified by match to protein family HMM PF00419 YP_002273841.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002273842.1 identified by match to protein family HMM PF00577 YP_002273843.1 identified by match to protein family HMM PF00419 YP_002273844.1 identified by match to protein family HMM PF00419 YP_002273845.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160 YP_002273846.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002273847.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002273848.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002273849.1 regulates the expression of uxuBA YP_002273851.1 identified by glimmer YP_002273852.1 identified by glimmer YP_002273853.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_002273854.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR01975 YP_002273855.1 identified by match to protein family HMM PF07670 YP_002273856.1 identified by match to protein family HMM PF07670 YP_002273857.1 identified by glimmer YP_002273858.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690 YP_002273859.1 identified by match to protein family HMM PF06977 YP_002273860.1 identified by glimmer YP_002273862.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241 YP_002273863.1 identified by match to protein family HMM PF06050 YP_002273864.1 identified by match to protein family HMM PF04286 YP_002273865.1 identified by match to protein family HMM PF07690 YP_002273866.1 identified by glimmer YP_002273867.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002273868.1 identified by match to protein family HMM PF06568 YP_002273869.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_002273870.1 identified by match to protein family HMM PF01420 YP_002273871.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02384 YP_002273872.1 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463 YP_002273873.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002273874.1 identified by match to protein family HMM PF04328 YP_002273875.1 identified by match to protein family HMM PF02554 YP_002273877.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002273878.1 identified by match to protein family HMM PF07690 YP_002273879.1 identified by match to protein family HMM PF07729 YP_002273880.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002273881.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_002273883.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_002273884.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_002273885.1 overlaps another CDS with the same product name YP_002273886.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF06738 YP_002273887.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00196 YP_002273888.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_002273889.1 identified by match to protein family HMM PF06276 YP_002273890.1 identified by match to protein family HMM PF07256 YP_002273891.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_002273892.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002273893.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_002273894.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_002273895.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002273896.1 identified by match to protein family HMM PF04972 YP_002273897.1 identified by glimmer YP_002273898.1 identified by match to protein family HMM PF01734 YP_002273899.1 identified by match to protein family HMM PF01026 YP_002273900.1 identified by match to protein family HMM PF04055 YP_002273902.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002273903.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_002273904.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002273905.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002273906.1 identified by match to protein family HMM PF01381 YP_002273907.1 in E. coli the lipoate ligase A catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes; creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_002273908.1 catalyzes the formation of serine from O-phosphoserine YP_002273909.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002273910.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_002273912.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_002273913.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_002273914.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_002273915.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002273916.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_002273917.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002273918.1 identified by match to protein family HMM PF05981 YP_002273919.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_002273920.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_002273921.1 identified by match to protein family HMM PF06123 YP_002273922.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002273923.1 member of the SPOUT superfamily of methyltransferases