-- dump date 20140619_090004 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_003075974.1 254791137 8220053 complement(133..351) 1 NC_013008.1 hypothetical protein 351 8220053 ECSP_0001 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075974.1 133 R 544404 CDS YP_003075975.1 254791138 8214568 360..2816 1 NC_013008.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2816 thrA 8214568 thrA Escherichia coli O157:H7 str. TW14359 bifunctional aspartokinase I/homoserine dehydrogenase I YP_003075975.1 360 D 544404 CDS YP_003075976.1 254791139 8214569 2818..3750 1 NC_013008.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3750 8214569 ECSP_0003 Escherichia coli O157:H7 str. TW14359 homoserine kinase YP_003075976.1 2818 D 544404 CDS YP_003075977.1 254791140 8214570 3751..5037 1 NC_013008.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5037 thrC 8214570 thrC Escherichia coli O157:H7 str. TW14359 threonine synthase YP_003075977.1 3751 D 544404 CDS YP_003075978.1 254791141 8214571 5251..5547 1 NC_013008.1 hypothetical protein 5547 yaaX 8214571 yaaX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075978.1 5251 D 544404 CDS YP_003075979.1 254791142 8214572 complement(5700..6476) 1 NC_013008.1 hypothetical protein 6476 yaaA 8214572 yaaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075979.1 5700 R 544404 CDS YP_003075980.1 254791143 8214573 complement(6546..7976) 1 NC_013008.1 transporter 7976 yaaJ 8214573 yaaJ Escherichia coli O157:H7 str. TW14359 transporter YP_003075980.1 6546 R 544404 CDS YP_003075981.1 254791144 8214574 8255..9208 1 NC_013008.1 transaldolase B 9208 talB 8214574 talB Escherichia coli O157:H7 str. TW14359 transaldolase B YP_003075981.1 8255 D 544404 CDS YP_003075982.1 254791145 8214575 9323..9910 1 NC_013008.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9910 mogA 8214575 mogA Escherichia coli O157:H7 str. TW14359 molybdenum cofactor biosynthesis protein MogA YP_003075982.1 9323 D 544404 CDS YP_003075983.1 254791146 8214576 complement(9945..10511) 1 NC_013008.1 hypothetical protein 10511 yaaH 8214576 yaaH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075983.1 9945 R 544404 CDS YP_003075984.1 254791147 8214577 complement(10660..11373) 1 NC_013008.1 hypothetical protein 11373 yaaW 8214577 yaaW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075984.1 10660 R 544404 CDS YP_003075985.1 254791148 8214578 complement(11399..11803) 1 NC_013008.1 hypothetical protein 11803 yaaI 8214578 yaaI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075985.1 11399 R 544404 CDS YP_003075986.1 254791149 8214579 complement(11938..12087) 1 NC_013008.1 hypothetical protein 12087 8214579 ECSP_0013 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075986.1 11938 R 544404 CDS YP_003075987.1 254791150 8214580 12180..14096 1 NC_013008.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14096 dnaK 8214580 dnaK Escherichia coli O157:H7 str. TW14359 molecular chaperone DnaK YP_003075987.1 12180 D 544404 CDS YP_003075988.1 254791151 8214581 14185..15315 1 NC_013008.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 15315 dnaJ 8214581 dnaJ Escherichia coli O157:H7 str. TW14359 molecular chaperone DnaJ YP_003075988.1 14185 D 544404 CDS YP_003075989.1 254791152 8214582 complement(15419..15628) 1 NC_013008.1 regulatory peptide 15628 mokC 8214582 mokC Escherichia coli O157:H7 str. TW14359 regulatory peptide YP_003075989.1 15419 R 544404 CDS YP_003075990.1 254791153 8214583 16157..17323 1 NC_013008.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 17323 nhaA 8214583 nhaA Escherichia coli O157:H7 str. TW14359 pH-dependent sodium/proton antiporter YP_003075990.1 16157 D 544404 CDS YP_003075991.1 254791154 8214584 17383..18288 1 NC_013008.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 18288 nhaR 8214584 nhaR Escherichia coli O157:H7 str. TW14359 transcriptional activator NhaR YP_003075991.1 17383 D 544404 CDS YP_003075992.1 254791155 8214587 complement(21762..22445) 1 NC_013008.1 chaperone protein 22445 8214587 ECSP_0021 Escherichia coli O157:H7 str. TW14359 chaperone protein YP_003075992.1 21762 R 544404 CDS YP_003075993.1 254791156 8214588 complement(22495..23028) 1 NC_013008.1 type-1 fimbrial protein 23028 8214588 ECSP_0022 Escherichia coli O157:H7 str. TW14359 type-1 fimbrial protein YP_003075993.1 22495 R 544404 CDS YP_003075994.1 254791157 8214589 complement(23330..24751) 1 NC_013008.1 non-LEE-encoded type III effector 24751 espX1 8214589 espX1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003075994.1 23330 R 544404 CDS YP_003075995.1 254791158 8214590 complement(25221..25484) 1 NC_013008.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 25484 rpsT 8214590 rpsT Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S20 YP_003075995.1 25221 R 544404 CDS YP_003075996.1 254791159 8214591 25587..25811 1 NC_013008.1 hypothetical protein 25811 yaaY 8214591 yaaY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003075996.1 25587 D 544404 CDS YP_003075997.1 254791160 8214592 25819..26760 1 NC_013008.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 26760 ribF 8214592 ribF Escherichia coli O157:H7 str. TW14359 bifunctional riboflavin kinase/FMN adenylyltransferase YP_003075997.1 25819 D 544404 CDS YP_003075998.1 254791161 8214593 26803..29619 1 NC_013008.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 29619 ileS 8214593 ileS Escherichia coli O157:H7 str. TW14359 isoleucyl-tRNA synthetase YP_003075998.1 26803 D 544404 CDS YP_003075999.1 254791162 8214594 29619..30113 1 NC_013008.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 30113 lspA 8214594 lspA Escherichia coli O157:H7 str. TW14359 lipoprotein signal peptidase YP_003075999.1 29619 D 544404 CDS YP_003076000.1 254791163 8214595 30201..30650 1 NC_013008.1 FKBP-type peptidylprolyl isomerase 30650 fkpB 8214595 fkpB Escherichia coli O157:H7 str. TW14359 FKBP-type peptidylprolyl isomerase YP_003076000.1 30201 D 544404 CDS YP_003076001.1 254791164 8214596 30652..31602 1 NC_013008.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 31602 ispH 8214596 ispH Escherichia coli O157:H7 str. TW14359 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_003076001.1 30652 D 544404 CDS YP_003076002.1 254791165 8214597 31668..32582 1 NC_013008.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 32582 rihC 8214597 rihC Escherichia coli O157:H7 str. TW14359 ribonucleoside hydrolase RihC YP_003076002.1 31668 D 544404 CDS YP_003076003.1 254791166 8214598 32749..33570 1 NC_013008.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 33570 dapB 8214598 dapB Escherichia coli O157:H7 str. TW14359 dihydrodipicolinate reductase YP_003076003.1 32749 D 544404 CDS YP_003076004.1 254791167 8214599 33849..33986 1 NC_013008.1 hypothetical protein 33986 8214599 ECSP_0033 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076004.1 33849 D 544404 CDS YP_003076005.1 254791168 8214600 34026..35174 1 NC_013008.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 35174 carA 8214600 carA Escherichia coli O157:H7 str. TW14359 carbamoyl phosphate synthase small subunit YP_003076005.1 34026 D 544404 CDS YP_003076006.1 254791169 8214601 35192..38413 1 NC_013008.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 38413 carB 8214601 carB Escherichia coli O157:H7 str. TW14359 carbamoyl phosphate synthase large subunit YP_003076006.1 35192 D 544404 CDS YP_003076007.1 254791170 8214602 complement(38421..38639) 1 NC_013008.1 hypothetical protein 38639 8214602 ECSP_0036 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076007.1 38421 R 544404 CDS YP_003076008.1 254791171 8214603 38674..39069 1 NC_013008.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 39069 caiF 8214603 caiF Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator CaiF YP_003076008.1 38674 D 544404 CDS YP_003076009.1 254791172 8214604 complement(39188..39778) 1 NC_013008.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 39778 caiE 8214604 caiE Escherichia coli O157:H7 str. TW14359 carnitine operon protein CaiE YP_003076009.1 39188 R 544404 CDS YP_003076010.1 254791173 8214605 complement(39784..40569) 1 NC_013008.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 40569 caiD 8214605 caiD Escherichia coli O157:H7 str. TW14359 carnitinyl-CoA dehydratase YP_003076010.1 39784 R 544404 CDS YP_003076011.1 254791174 8214606 complement(40678..42231) 1 NC_013008.1 crotonobetaine/carnitine-CoA ligase 42231 caiC 8214606 caiC Escherichia coli O157:H7 str. TW14359 crotonobetaine/carnitine-CoA ligase YP_003076011.1 40678 R 544404 CDS YP_003076012.1 254791175 8214607 complement(42305..43522) 1 NC_013008.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 43522 caiB 8214607 caiB Escherichia coli O157:H7 str. TW14359 crotonobetainyl-CoA:carnitine CoA-transferase YP_003076012.1 42305 R 544404 CDS YP_003076013.1 254791176 8214608 complement(43651..44793) 1 NC_013008.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 44793 caiA 8214608 caiA Escherichia coli O157:H7 str. TW14359 crotonobetainyl-CoA dehydrogenase YP_003076013.1 43651 R 544404 CDS YP_003076014.1 254791177 8214609 complement(44824..46338) 1 NC_013008.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 46338 caiT 8214609 caiT Escherichia coli O157:H7 str. TW14359 L-carnitine/gamma-butyrobetaine antiporter YP_003076014.1 44824 R 544404 CDS YP_003076015.1 254791178 8214610 46812..47582 1 NC_013008.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 47582 fixA 8214610 fixA Escherichia coli O157:H7 str. TW14359 electron transfer flavoprotein FixA YP_003076015.1 46812 D 544404 CDS YP_003076016.1 254791179 8214611 47597..48538 1 NC_013008.1 involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 48538 fixB 8214611 fixB Escherichia coli O157:H7 str. TW14359 electron transfer flavoprotein FixB YP_003076016.1 47597 D 544404 CDS YP_003076017.1 254791180 8214612 48589..49875 1 NC_013008.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 49875 fixC 8214612 fixC Escherichia coli O157:H7 str. TW14359 oxidoreductase FixC YP_003076017.1 48589 D 544404 CDS YP_003076018.1 254791181 8214613 49872..50159 1 NC_013008.1 4Fe-4S ferredoxin-type protein 50159 fixX 8214613 fixX Escherichia coli O157:H7 str. TW14359 4Fe-4S ferredoxin-type protein YP_003076018.1 49872 D 544404 CDS YP_003076019.1 254791182 8214614 50217..51548 1 NC_013008.1 transporter 51548 yaaU 8214614 yaaU Escherichia coli O157:H7 str. TW14359 transporter YP_003076019.1 50217 D 544404 CDS YP_003076020.1 254791183 8214615 51656..52186 1 NC_013008.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 52186 kefF 8214615 kefF Escherichia coli O157:H7 str. TW14359 glutathione-regulated potassium-efflux system ancillary protein KefF YP_003076020.1 51656 D 544404 CDS YP_003076021.1 254791184 8214616 52179..54041 1 NC_013008.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 54041 kefC 8214616 kefC Escherichia coli O157:H7 str. TW14359 glutathione-regulated potassium-efflux system protein KefC YP_003076021.1 52179 D 544404 CDS YP_003076022.1 254791185 8214617 54233..54712 1 NC_013008.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 54712 folA 8214617 folA Escherichia coli O157:H7 str. TW14359 dihydrofolate reductase YP_003076022.1 54233 D 544404 CDS YP_003076023.1 254791186 8214618 54798..55031 1 NC_013008.1 antitoxin of gyrase inhibiting toxin-antitoxin system 55031 8214618 ECSP_0052 Escherichia coli O157:H7 str. TW14359 antitoxin of gyrase inhibiting toxin-antitoxin system YP_003076023.1 54798 D 544404 CDS YP_003076024.1 254791187 8214619 55034..55348 1 NC_013008.1 toxin of gyrase inhibiting toxin-antitoxin system 55348 8214619 ECSP_0053 Escherichia coli O157:H7 str. TW14359 toxin of gyrase inhibiting toxin-antitoxin system YP_003076024.1 55034 D 544404 CDS YP_003076025.1 254791188 8214620 complement(55345..56193) 1 NC_013008.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 56193 apaH 8214620 apaH Escherichia coli O157:H7 str. TW14359 diadenosine tetraphosphatase YP_003076025.1 55345 R 544404 CDS YP_003076026.1 254791189 8214621 complement(56200..56577) 1 NC_013008.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 56577 apaG 8214621 apaG Escherichia coli O157:H7 str. TW14359 ApaG protein YP_003076026.1 56200 R 544404 CDS YP_003076027.1 254791190 8214622 complement(56580..57401) 1 NC_013008.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 57401 ksgA 8214622 ksgA Escherichia coli O157:H7 str. TW14359 dimethyladenosine transferase YP_003076027.1 56580 R 544404 CDS YP_003076028.1 254791191 8214623 complement(57398..58387) 1 NC_013008.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 58387 pdxA 8214623 pdxA Escherichia coli O157:H7 str. TW14359 4-hydroxythreonine-4-phosphate dehydrogenase YP_003076028.1 57398 R 544404 CDS YP_003076029.1 254791192 8214624 complement(58387..59673) 1 NC_013008.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 59673 surA 8214624 surA Escherichia coli O157:H7 str. TW14359 peptidyl-prolyl cis-trans isomerase SurA YP_003076029.1 58387 R 544404 CDS YP_003076030.1 254791193 8214625 complement(59726..62080) 1 NC_013008.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 62080 imp 8214625 imp Escherichia coli O157:H7 str. TW14359 organic solvent tolerance protein YP_003076030.1 59726 R 544404 CDS YP_003076031.1 254791194 8214626 62335..63150 1 NC_013008.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 63150 djlA 8214626 djlA Escherichia coli O157:H7 str. TW14359 Dna-J like membrane chaperone protein YP_003076031.1 62335 D 544404 CDS YP_003076032.1 254791195 8214627 63445..64182 1 NC_013008.1 non-LEE-encoded type III effector 64182 espY1 8214627 espY1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076032.1 63445 D 544404 CDS YP_003076033.1 254791196 8214628 complement(64600..65259) 1 NC_013008.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 65259 rluA 8214628 rluA Escherichia coli O157:H7 str. TW14359 23S rRNA/tRNA pseudouridine synthase A YP_003076033.1 64600 R 544404 CDS YP_003076034.1 254791197 8214629 complement(65271..68177) 1 NC_013008.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 68177 hepA 8214629 hepA Escherichia coli O157:H7 str. TW14359 ATP-dependent helicase HepA YP_003076034.1 65271 R 544404 CDS YP_003076035.1 254791198 8214630 complement(68341..70692) 1 NC_013008.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 70692 polB 8214630 polB Escherichia coli O157:H7 str. TW14359 DNA polymerase II YP_003076035.1 68341 R 544404 CDS YP_003076036.1 254791199 8214631 complement(70767..71462) 1 NC_013008.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 71462 araD 8214631 araD Escherichia coli O157:H7 str. TW14359 L-ribulose-5-phosphate 4-epimerase YP_003076036.1 70767 R 544404 CDS YP_003076037.1 254791200 8214632 complement(71662..73164) 1 NC_013008.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 73164 araA 8214632 araA Escherichia coli O157:H7 str. TW14359 L-arabinose isomerase YP_003076037.1 71662 R 544404 CDS YP_003076038.1 254791201 8214633 complement(73175..74875) 1 NC_013008.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 74875 araB 8214633 araB Escherichia coli O157:H7 str. TW14359 ribulokinase YP_003076038.1 73175 R 544404 CDS YP_003076039.1 254791202 8214634 75214..76092 1 NC_013008.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; AraC family transcriptional regulator 76092 araC 8214634 araC Escherichia coli O157:H7 str. TW14359 AraC family transcriptional regulator YP_003076039.1 75214 D 544404 CDS YP_003076040.1 254791203 8214635 76178..76942 1 NC_013008.1 hypothetical protein 76942 yabI 8214635 yabI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076040.1 76178 D 544404 CDS YP_003076041.1 254791204 8214636 complement(77029..77727) 1 NC_013008.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 77727 thiQ 8214636 thiQ Escherichia coli O157:H7 str. TW14359 thiamine transporter ATP-binding subunit YP_003076041.1 77029 R 544404 CDS YP_003076042.1 254791205 8214637 complement(77711..79321) 1 NC_013008.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 79321 thiP 8214637 thiP Escherichia coli O157:H7 str. TW14359 thiamine transporter membrane protein YP_003076042.1 77711 R 544404 CDS YP_003076043.1 254791206 8214638 complement(79297..80280) 1 NC_013008.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 80280 tbpA 8214638 tbpA Escherichia coli O157:H7 str. TW14359 thiamine transporter substrate binding subunit YP_003076043.1 79297 R 544404 CDS YP_003076044.1 254791207 8214639 80652..81221 1 NC_013008.1 non-LEE-encoded type III effector 81221 espY2 8214639 espY2 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076044.1 80652 D 544404 CDS YP_003076045.1 254791208 8214640 complement(81450..83108) 1 NC_013008.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 83108 sgrR 8214640 sgrR Escherichia coli O157:H7 str. TW14359 transcriptional regulator SgrR YP_003076045.1 81450 R 544404 CDS YP_003076046.1 254791209 8214641 complement(83436..84041) 1 NC_013008.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 84041 leuD 8214641 leuD Escherichia coli O157:H7 str. TW14359 isopropylmalate isomerase small subunit YP_003076046.1 83436 R 544404 CDS YP_003076047.1 254791210 8214642 complement(84052..85452) 1 NC_013008.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 85452 leuC 8214642 leuC Escherichia coli O157:H7 str. TW14359 isopropylmalate isomerase large subunit YP_003076047.1 84052 R 544404 CDS YP_003076048.1 254791211 8214643 complement(85455..86546) 1 NC_013008.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 86546 leuB 8214643 leuB Escherichia coli O157:H7 str. TW14359 3-isopropylmalate dehydrogenase YP_003076048.1 85455 R 544404 CDS YP_003076049.1 254791212 8214644 complement(86546..88117) 1 NC_013008.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 88117 leuA 8214644 leuA Escherichia coli O157:H7 str. TW14359 2-isopropylmalate synthase YP_003076049.1 86546 R 544404 CDS YP_003076050.1 254791213 8214645 complement(88210..88296) 1 NC_013008.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 88296 leuL 8214645 leuL Escherichia coli O157:H7 str. TW14359 leu operon leader peptide YP_003076050.1 88210 R 544404 CDS YP_003076051.1 254791214 8214646 88954..89898 1 NC_013008.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 89898 leuO 8214646 leuO Escherichia coli O157:H7 str. TW14359 leucine transcriptional activator YP_003076051.1 88954 D 544404 CDS YP_003076052.1 254791215 8214647 90216..91940 1 NC_013008.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 91940 ilvI 8214647 ilvI Escherichia coli O157:H7 str. TW14359 acetolactate synthase 3 catalytic subunit YP_003076052.1 90216 D 544404 CDS YP_003076053.1 254791216 8214648 91943..92434 1 NC_013008.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 92434 ilvH 8214648 ilvH Escherichia coli O157:H7 str. TW14359 acetolactate synthase 3 regulatory subunit YP_003076053.1 91943 D 544404 CDS YP_003076054.1 254791217 8214649 92614..93618 1 NC_013008.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 93618 fruR 8214649 fruR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator FruR YP_003076054.1 92614 D 544404 CDS YP_003076055.1 254791218 8214650 94220..94678 1 NC_013008.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 94678 mraZ 8214650 mraZ Escherichia coli O157:H7 str. TW14359 cell division protein MraZ YP_003076055.1 94220 D 544404 CDS YP_003076056.1 254791219 8214651 94680..95621 1 NC_013008.1 S-adenosyl-methyltransferase MraW 95621 mraW 8214651 mraW Escherichia coli O157:H7 str. TW14359 S-adenosyl-methyltransferase MraW YP_003076056.1 94680 D 544404 CDS YP_003076057.1 254791220 8214652 95618..95983 1 NC_013008.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 95983 ftsL 8214652 ftsL Escherichia coli O157:H7 str. TW14359 cell division protein FtsL YP_003076057.1 95618 D 544404 CDS YP_003076058.1 254791221 8214653 95999..97765 1 NC_013008.1 transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 97765 ftsI 8214653 ftsI Escherichia coli O157:H7 str. TW14359 transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) YP_003076058.1 95999 D 544404 CDS YP_003076059.1 254791222 8214654 97752..99239 1 NC_013008.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 99239 murE 8214654 murE Escherichia coli O157:H7 str. TW14359 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_003076059.1 97752 D 544404 CDS YP_003076060.1 254791223 8214655 99236..100594 1 NC_013008.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 100594 murF 8214655 murF Escherichia coli O157:H7 str. TW14359 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_003076060.1 99236 D 544404 CDS YP_003076061.1 254791224 8214656 100588..101670 1 NC_013008.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 101670 mraY 8214656 mraY Escherichia coli O157:H7 str. TW14359 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_003076061.1 100588 D 544404 CDS YP_003076062.1 254791225 8214657 101673..102989 1 NC_013008.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 102989 murD 8214657 murD Escherichia coli O157:H7 str. TW14359 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_003076062.1 101673 D 544404 CDS YP_003076063.1 254791226 8214658 102989..104233 1 NC_013008.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 104233 ftsW 8214658 ftsW Escherichia coli O157:H7 str. TW14359 cell division protein FtsW YP_003076063.1 102989 D 544404 CDS YP_003076064.1 254791227 8214659 104230..105297 1 NC_013008.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 105297 murG 8214659 murG Escherichia coli O157:H7 str. TW14359 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_003076064.1 104230 D 544404 CDS YP_003076065.1 254791228 8214660 105351..106826 1 NC_013008.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 106826 murC 8214660 murC Escherichia coli O157:H7 str. TW14359 UDP-N-acetylmuramate--L-alanine ligase YP_003076065.1 105351 D 544404 CDS YP_003076066.1 254791229 8214661 106819..107739 1 NC_013008.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 107739 ddl 8214661 ddl Escherichia coli O157:H7 str. TW14359 D-alanine--D-alanine ligase YP_003076066.1 106819 D 544404 CDS YP_003076067.1 254791230 8214662 107741..108571 1 NC_013008.1 involved in septum formation; cell division protein FtsQ 108571 ftsQ 8214662 ftsQ Escherichia coli O157:H7 str. TW14359 cell division protein FtsQ YP_003076067.1 107741 D 544404 CDS YP_003076068.1 254791231 8214663 108568..109830 1 NC_013008.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 109830 ftsA 8214663 ftsA Escherichia coli O157:H7 str. TW14359 cell division protein FtsA YP_003076068.1 108568 D 544404 CDS YP_003076069.1 254791232 8214664 109891..111042 1 NC_013008.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 111042 ftsZ 8214664 ftsZ Escherichia coli O157:H7 str. TW14359 cell division protein FtsZ YP_003076069.1 109891 D 544404 CDS YP_003076070.1 254791233 8214665 111143..112060 1 NC_013008.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 112060 lpxC 8214665 lpxC Escherichia coli O157:H7 str. TW14359 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_003076070.1 111143 D 544404 CDS YP_003076071.1 254791234 8214666 112291..112803 1 NC_013008.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112803 secM 8214666 secM Escherichia coli O157:H7 str. TW14359 SecA regulator SecM YP_003076071.1 112291 D 544404 CDS YP_003076072.1 254791235 8214667 112865..115570 1 NC_013008.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 115570 secA 8214667 secA Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecA YP_003076072.1 112865 D 544404 CDS YP_003076073.1 254791236 8214668 115630..116028 1 NC_013008.1 nucleoside triphosphate pyrophosphohydrolase 116028 mutT 8214668 mutT Escherichia coli O157:H7 str. TW14359 nucleoside triphosphate pyrophosphohydrolase YP_003076073.1 115630 D 544404 CDS YP_003076074.1 254791237 8214669 complement(116119..116316) 1 NC_013008.1 zinc-binding protein 116316 yacG 8214669 yacG Escherichia coli O157:H7 str. TW14359 zinc-binding protein YP_003076074.1 116119 R 544404 CDS YP_003076075.1 254791238 8214670 complement(116326..117069) 1 NC_013008.1 hypothetical protein 117069 yacF 8214670 yacF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076075.1 116326 R 544404 CDS YP_003076076.1 254791239 8214671 complement(117069..117689) 1 NC_013008.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 117689 coaE 8214671 coaE Escherichia coli O157:H7 str. TW14359 dephospho-CoA kinase YP_003076076.1 117069 R 544404 CDS YP_003076077.1 254791240 8214672 117914..118957 1 NC_013008.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 118957 guaC 8214672 guaC Escherichia coli O157:H7 str. TW14359 guanosine 5'-monophosphate oxidoreductase YP_003076077.1 117914 D 544404 CDS YP_003076078.1 254791241 8214673 complement(118992..120194) 1 NC_013008.1 type IV pilin biogenesis protein 120194 hcpC 8214673 hcpC Escherichia coli O157:H7 str. TW14359 type IV pilin biogenesis protein YP_003076078.1 118992 R 544404 CDS YP_003076079.1 254791242 8214674 complement(120184..121569) 1 NC_013008.1 hypothetical protein 121569 hcpB 8214674 hcpB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076079.1 120184 R 544404 CDS YP_003076080.1 254791243 8214675 complement(121579..122019) 1 NC_013008.1 major pilin subunit 122019 hcpA 8214675 hcpA Escherichia coli O157:H7 str. TW14359 major pilin subunit YP_003076080.1 121579 R 544404 CDS YP_003076081.1 254791244 8214676 complement(122222..123115) 1 NC_013008.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 123115 nadC 8214676 nadC Escherichia coli O157:H7 str. TW14359 quinolinate phosphoribosyltransferase YP_003076081.1 122222 R 544404 CDS YP_003076082.1 254791245 8214677 123203..123754 1 NC_013008.1 N-acetyl-anhydromuranmyl-L-alanine amidase 123754 ampD 8214677 ampD Escherichia coli O157:H7 str. TW14359 N-acetyl-anhydromuranmyl-L-alanine amidase YP_003076082.1 123203 D 544404 CDS YP_003076083.1 254791246 8214678 123751..124605 1 NC_013008.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 124605 ampE 8214678 ampE Escherichia coli O157:H7 str. TW14359 regulatory protein AmpE YP_003076083.1 123751 D 544404 CDS YP_003076084.1 254791247 8214679 complement(124648..126021) 1 NC_013008.1 aromatic amino acid transporter 126021 aroP 8214679 aroP Escherichia coli O157:H7 str. TW14359 aromatic amino acid transporter YP_003076084.1 124648 R 544404 CDS YP_003076085.1 254791248 8214680 126562..127326 1 NC_013008.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 127326 pdhR 8214680 pdhR Escherichia coli O157:H7 str. TW14359 transcriptional regulator PdhR YP_003076085.1 126562 D 544404 CDS YP_003076086.1 254791249 8214681 127487..130150 1 NC_013008.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 130150 aceE 8214681 aceE Escherichia coli O157:H7 str. TW14359 pyruvate dehydrogenase subunit E1 YP_003076086.1 127487 D 544404 CDS YP_003076087.1 254791250 8214682 130165..132057 1 NC_013008.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 132057 aceF 8214682 aceF Escherichia coli O157:H7 str. TW14359 dihydrolipoamide acetyltransferase YP_003076087.1 130165 D 544404 CDS YP_003076088.1 254791251 8214683 132265..133689 1 NC_013008.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 133689 lpd 8214683 lpd Escherichia coli O157:H7 str. TW14359 dihydrolipoamide dehydrogenase YP_003076088.1 132265 D 544404 CDS YP_003076089.1 254791252 8214684 complement(133760..135613) 1 NC_013008.1 hypothetical protein 135613 yacH 8214684 yacH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076089.1 133760 R 544404 CDS YP_003076090.1 254791253 8214685 135968..138565 1 NC_013008.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 138565 acnB 8214685 acnB Escherichia coli O157:H7 str. TW14359 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_003076090.1 135968 D 544404 CDS YP_003076091.1 254791254 8214686 138741..139103 1 NC_013008.1 hypothetical protein 139103 yacL 8214686 yacL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076091.1 138741 D 544404 CDS YP_003076092.1 254791255 8214687 complement(139141..139935) 1 NC_013008.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 139935 speD 8214687 speD Escherichia coli O157:H7 str. TW14359 S-adenosylmethionine decarboxylase YP_003076092.1 139141 R 544404 CDS YP_003076093.1 254791256 8214688 complement(139951..140817) 1 NC_013008.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 140817 speE 8214688 speE Escherichia coli O157:H7 str. TW14359 spermidine synthase YP_003076093.1 139951 R 544404 CDS YP_003076094.1 254791257 8214689 complement(140923..141270) 1 NC_013008.1 hypothetical protein 141270 yacC 8214689 yacC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076094.1 140923 R 544404 CDS YP_003076095.1 254791258 8214690 141436..142986 1 NC_013008.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 142986 cueO 8214690 cueO Escherichia coli O157:H7 str. TW14359 multicopper oxidase YP_003076095.1 141436 D 544404 CDS YP_003076096.1 254791259 8214691 complement(143188..145578) 1 NC_013008.1 glucose dehydrogenase 145578 gcd 8214691 gcd Escherichia coli O157:H7 str. TW14359 glucose dehydrogenase YP_003076096.1 143188 R 544404 CDS YP_003076097.1 254791260 8214692 145784..146320 1 NC_013008.1 hypoxanthine phosphoribosyltransferase 146320 hpt 8214692 hpt Escherichia coli O157:H7 str. TW14359 hypoxanthine phosphoribosyltransferase YP_003076097.1 145784 D 544404 CDS YP_003076098.1 254791261 8214693 complement(146361..147023) 1 NC_013008.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 147023 can 8214693 can Escherichia coli O157:H7 str. TW14359 carbonic anhydrase YP_003076098.1 146361 R 544404 CDS YP_003076099.1 254791262 8214694 147132..148058 1 NC_013008.1 ABC transporter ATP-binding protein 148058 yadG 8214694 yadG Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YP_003076099.1 147132 D 544404 CDS YP_003076100.1 254791263 8214695 148055..148825 1 NC_013008.1 ABC transporter membrane protein 148825 yadH 8214695 yadH Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003076100.1 148055 D 544404 CDS YP_003076101.1 254791264 8214696 148930..149370 1 NC_013008.1 PTS Enzyme IIA 149370 yadI 8214696 yadI Escherichia coli O157:H7 str. TW14359 PTS Enzyme IIA YP_003076101.1 148930 D 544404 CDS YP_003076102.1 254791265 8214697 149434..150663 1 NC_013008.1 polysaccharide deacetylase lipoprotein 150663 yadE 8214697 yadE Escherichia coli O157:H7 str. TW14359 polysaccharide deacetylase lipoprotein YP_003076102.1 149434 D 544404 CDS YP_003076103.1 254791266 8214698 complement(150667..151047) 1 NC_013008.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 151047 panD 8214698 panD Escherichia coli O157:H7 str. TW14359 aspartate alpha-decarboxylase YP_003076103.1 150667 R 544404 CDS YP_003076104.1 254791267 8214699 151321..152217 1 NC_013008.1 transposase 152217 yadD 8214699 yadD Escherichia coli O157:H7 str. TW14359 transposase YP_003076104.1 151321 D 544404 CDS YP_003076105.1 254791268 8214700 complement(152516..153367) 1 NC_013008.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 153367 panC 8214700 panC Escherichia coli O157:H7 str. TW14359 pantoate--beta-alanine ligase YP_003076105.1 152516 R 544404 CDS YP_003076106.1 254791269 8214701 complement(153379..154173) 1 NC_013008.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 154173 panB 8214701 panB Escherichia coli O157:H7 str. TW14359 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_003076106.1 153379 R 544404 CDS YP_003076107.1 254791270 8214702 complement(154308..155417) 1 NC_013008.1 fimbrial protein 155417 yadC 8214702 yadC Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003076107.1 154308 R 544404 CDS YP_003076108.1 254791271 8214703 complement(155429..156019) 1 NC_013008.1 fimbrial protein 156019 yadK 8214703 yadK Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003076108.1 155429 R 544404 CDS YP_003076109.1 254791272 8214704 complement(156040..156645) 1 NC_013008.1 fimbrial protein 156645 yadL 8214704 yadL Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003076109.1 156040 R 544404 CDS YP_003076110.1 254791273 8214705 complement(156660..157220) 1 NC_013008.1 fimbrial protein 157220 yadM 8214705 yadM Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003076110.1 156660 R 544404 CDS YP_003076111.1 254791274 8214706 complement(157222..159822) 1 NC_013008.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 159822 htrE 8214706 htrE Escherichia coli O157:H7 str. TW14359 outer membrane usher protein YP_003076111.1 157222 R 544404 CDS YP_003076112.1 254791275 8214707 complement(159864..160589) 1 NC_013008.1 chaperone protein EcpD 160589 8214707 ECSP_0141 Escherichia coli O157:H7 str. TW14359 chaperone protein EcpD YP_003076112.1 159864 R 544404 CDS YP_003076113.1 254791276 8214708 complement(160676..161281) 1 NC_013008.1 fimbrial protein 161281 yadN 8214708 yadN Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003076113.1 160676 R 544404 CDS YP_003076114.1 254791277 8214709 complement(161553..162035) 1 NC_013008.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 162035 folK 8214709 folK Escherichia coli O157:H7 str. TW14359 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_003076114.1 161553 R 544404 CDS YP_003076115.1 254791278 8214710 complement(162032..163429) 1 NC_013008.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase 163429 pcnB 8214710 pcnB Escherichia coli O157:H7 str. TW14359 poly(A) polymerase YP_003076115.1 162032 R 544404 CDS YP_003076116.1 254791279 8214711 complement(163489..164415) 1 NC_013008.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 164415 yadB 8214711 yadB Escherichia coli O157:H7 str. TW14359 glutamyl-Q tRNA(Asp) synthetase YP_003076116.1 163489 R 544404 CDS YP_003076117.1 254791280 8214712 complement(164452..164907) 1 NC_013008.1 RNA polymerase-binding transcription factor 164907 dksA 8214712 dksA Escherichia coli O157:H7 str. TW14359 RNA polymerase-binding transcription factor YP_003076117.1 164452 R 544404 CDS YP_003076118.1 254791281 8214713 complement(165085..165789) 1 NC_013008.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 165789 sfsA 8214713 sfsA Escherichia coli O157:H7 str. TW14359 sugar fermentation stimulation protein A YP_003076118.1 165085 R 544404 CDS YP_003076119.1 254791282 8214714 complement(165804..166334) 1 NC_013008.1 2'-5' RNA ligase 166334 ligT 8214714 ligT Escherichia coli O157:H7 str. TW14359 2'-5' RNA ligase YP_003076119.1 165804 R 544404 CDS YP_003076120.1 254791283 8214715 166408..168837 1 NC_013008.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 168837 hrpB 8214715 hrpB Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase HrpB YP_003076120.1 166408 D 544404 CDS YP_003076121.1 254791284 8214716 169033..171567 1 NC_013008.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 171567 mrcB 8214716 mrcB Escherichia coli O157:H7 str. TW14359 penicillin-binding protein 1b YP_003076121.1 169033 D 544404 CDS YP_003076122.1 254791285 8214717 171787..174030 1 NC_013008.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 174030 fhuA 8214717 fhuA Escherichia coli O157:H7 str. TW14359 ferrichrome outer membrane transporter YP_003076122.1 171787 D 544404 CDS YP_003076123.1 254791286 8214718 174081..174878 1 NC_013008.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 174878 fhuC 8214718 fhuC Escherichia coli O157:H7 str. TW14359 iron-hydroxamate transporter ATP-binding subunit YP_003076123.1 174081 D 544404 CDS YP_003076124.1 254791287 8214719 174878..175768 1 NC_013008.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 175768 fhuD 8214719 fhuD Escherichia coli O157:H7 str. TW14359 iron-hydroxamate transporter substrate-binding subunit YP_003076124.1 174878 D 544404 CDS YP_003076125.1 254791288 8214720 175765..177747 1 NC_013008.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 177747 fhuB 8214720 fhuB Escherichia coli O157:H7 str. TW14359 iron-hydroxamate transporter permease subunit YP_003076125.1 175765 D 544404 CDS YP_003076126.1 254791289 8214721 complement(177782..179062) 1 NC_013008.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 179062 hemL 8214721 hemL Escherichia coli O157:H7 str. TW14359 glutamate-1-semialdehyde aminotransferase YP_003076126.1 177782 R 544404 CDS YP_003076127.1 254791290 8214722 179287..180708 1 NC_013008.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 180708 clcA 8214722 clcA Escherichia coli O157:H7 str. TW14359 chloride channel protein YP_003076127.1 179287 D 544404 CDS YP_003076128.1 254791291 8214723 180790..181134 1 NC_013008.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 181134 yadR 8214723 yadR Escherichia coli O157:H7 str. TW14359 iron-sulfur cluster insertion protein ErpA YP_003076128.1 180790 D 544404 CDS YP_003076129.1 254791292 8214724 complement(181181..181804) 1 NC_013008.1 hypothetical protein 181804 yadS 8214724 yadS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076129.1 181181 R 544404 CDS YP_003076130.1 254791293 8214725 complement(181842..182642) 1 NC_013008.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 182642 btuF 8214725 btuF Escherichia coli O157:H7 str. TW14359 vitamin B12-transporter protein BtuF YP_003076130.1 181842 R 544404 CDS YP_003076131.1 254791294 8214726 complement(182635..183333) 1 NC_013008.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 183333 pfs 8214726 pfs Escherichia coli O157:H7 str. TW14359 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_003076131.1 182635 R 544404 CDS YP_003076132.1 254791295 8214727 183417..184934 1 NC_013008.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 184934 dgt 8214727 dgt Escherichia coli O157:H7 str. TW14359 deoxyguanosinetriphosphate triphosphohydrolase YP_003076132.1 183417 D 544404 CDS YP_003076133.1 254791296 8214728 185064..186488 1 NC_013008.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 186488 degP 8214728 degP Escherichia coli O157:H7 str. TW14359 serine endoprotease YP_003076133.1 185064 D 544404 CDS YP_003076134.1 254791297 8214729 186643..187800 1 NC_013008.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 187800 cdaR 8214729 cdaR Escherichia coli O157:H7 str. TW14359 carbohydrate diacid transcriptional activator CdaR YP_003076134.1 186643 D 544404 CDS YP_003076135.1 254791298 8214730 complement(187889..188275) 1 NC_013008.1 hypothetical protein 188275 yaeH 8214730 yaeH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076135.1 187889 R 544404 CDS YP_003076136.1 254791299 8214731 complement(188590..189414) 1 NC_013008.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 189414 dapD 8214731 dapD Escherichia coli O157:H7 str. TW14359 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_003076136.1 188590 R 544404 CDS YP_003076137.1 254791300 8214732 complement(189445..192117) 1 NC_013008.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 192117 glnD 8214732 glnD Escherichia coli O157:H7 str. TW14359 PII uridylyl-transferase YP_003076137.1 189445 R 544404 CDS YP_003076138.1 254791301 8214733 complement(192179..192973) 1 NC_013008.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 192973 map 8214733 map Escherichia coli O157:H7 str. TW14359 methionine aminopeptidase YP_003076138.1 192179 R 544404 CDS YP_003076139.1 254791302 8214734 193341..194066 1 NC_013008.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 194066 rpsB 8214734 rpsB Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S2 YP_003076139.1 193341 D 544404 CDS YP_003076140.1 254791303 8214735 194324..195175 1 NC_013008.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 195175 tsf 8214735 tsf Escherichia coli O157:H7 str. TW14359 elongation factor Ts YP_003076140.1 194324 D 544404 CDS YP_003076141.1 254791304 8214736 195322..196047 1 NC_013008.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 196047 pyrH 8214736 pyrH Escherichia coli O157:H7 str. TW14359 uridylate kinase YP_003076141.1 195322 D 544404 CDS YP_003076142.1 254791305 8214737 196197..196754 1 NC_013008.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 196754 frr 8214737 frr Escherichia coli O157:H7 str. TW14359 ribosome recycling factor YP_003076142.1 196197 D 544404 CDS YP_003076143.1 254791306 8214738 196846..198042 1 NC_013008.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 198042 dxr 8214738 dxr Escherichia coli O157:H7 str. TW14359 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_003076143.1 196846 D 544404 CDS YP_003076144.1 254791307 8214739 198228..198989 1 NC_013008.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 198989 ispU 8214739 ispU Escherichia coli O157:H7 str. TW14359 UDP pyrophosphate synthase YP_003076144.1 198228 D 544404 CDS YP_003076145.1 254791308 8214740 199002..199859 1 NC_013008.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 199859 cdsA 8214740 cdsA Escherichia coli O157:H7 str. TW14359 CDP-diglyceride synthase YP_003076145.1 199002 D 544404 CDS YP_003076146.1 254791309 8214741 199871..201223 1 NC_013008.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 201223 rseP 8214741 rseP Escherichia coli O157:H7 str. TW14359 zinc metallopeptidase RseP YP_003076146.1 199871 D 544404 CDS YP_003076147.1 254791310 8214742 201253..203685 1 NC_013008.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 203685 yaeT 8214742 yaeT Escherichia coli O157:H7 str. TW14359 outer membrane protein assembly factor YaeT YP_003076147.1 201253 D 544404 CDS YP_003076148.1 254791311 8214743 203806..204291 1 NC_013008.1 periplasmic chaperone 204291 hlpA 8214743 hlpA Escherichia coli O157:H7 str. TW14359 periplasmic chaperone YP_003076148.1 203806 D 544404 CDS YP_003076149.1 254791312 8214744 204295..205320 1 NC_013008.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 205320 lpxD 8214744 lpxD Escherichia coli O157:H7 str. TW14359 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_003076149.1 204295 D 544404 CDS YP_003076150.1 254791313 8214745 205425..205880 1 NC_013008.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 205880 fabZ 8214745 fabZ Escherichia coli O157:H7 str. TW14359 (3R)-hydroxymyristoyl-ACP dehydratase YP_003076150.1 205425 D 544404 CDS YP_003076151.1 254791314 8214746 205884..206672 1 NC_013008.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 206672 lpxA 8214746 lpxA Escherichia coli O157:H7 str. TW14359 UDP-N-acetylglucosamine acyltransferase YP_003076151.1 205884 D 544404 CDS YP_003076152.1 254791315 8214747 206672..207820 1 NC_013008.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 207820 lpxB 8214747 lpxB Escherichia coli O157:H7 str. TW14359 lipid-A-disaccharide synthase YP_003076152.1 206672 D 544404 CDS YP_003076153.1 254791316 8214748 207817..208413 1 NC_013008.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 208413 rnhB 8214748 rnhB Escherichia coli O157:H7 str. TW14359 ribonuclease HII YP_003076153.1 207817 D 544404 CDS YP_003076154.1 254791317 8214749 208450..211932 1 NC_013008.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 211932 dnaE 8214749 dnaE Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit alpha YP_003076154.1 208450 D 544404 CDS YP_003076155.1 254791318 8214750 211945..212904 1 NC_013008.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 212904 accA 8214750 accA Escherichia coli O157:H7 str. TW14359 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_003076155.1 211945 D 544404 CDS YP_003076156.1 254791319 8214751 213003..215144 1 NC_013008.1 lysine decarboxylase 2 215144 ldcC 8214751 ldcC Escherichia coli O157:H7 str. TW14359 lysine decarboxylase 2 YP_003076156.1 213003 D 544404 CDS YP_003076157.1 254791320 8214752 215201..215590 1 NC_013008.1 hypothetical protein 215590 yaeR 8214752 yaeR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076157.1 215201 D 544404 CDS YP_003076158.1 254791321 8214753 215655..216950 1 NC_013008.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 216950 tilS 8214753 tilS Escherichia coli O157:H7 str. TW14359 tRNA(Ile)-lysidine synthetase YP_003076158.1 215655 D 544404 CDS YP_003076159.1 254791322 8214754 complement(217003..217257) 1 NC_013008.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 217257 rof 8214754 rof Escherichia coli O157:H7 str. TW14359 Rho-binding antiterminator YP_003076159.1 217003 R 544404 CDS YP_003076160.1 254791323 8214755 217616..218161 1 NC_013008.1 hypothetical protein 218161 yaeQ 8214755 yaeQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076160.1 217616 D 544404 CDS YP_003076161.1 254791324 8214756 218158..218568 1 NC_013008.1 peptidyl-tRNA hydrolase domain-containing protein 218568 yaeJ 8214756 yaeJ Escherichia coli O157:H7 str. TW14359 peptidyl-tRNA hydrolase domain-containing protein YP_003076161.1 218158 D 544404 CDS YP_003076162.1 254791325 8214757 218582..219292 1 NC_013008.1 lipoprotein involved with copper homeostasis and adhesion 219292 nlpE 8214757 nlpE Escherichia coli O157:H7 str. TW14359 lipoprotein involved with copper homeostasis and adhesion YP_003076162.1 218582 D 544404 CDS YP_003076163.1 254791326 8214758 complement(219492..220316) 1 NC_013008.1 hypothetical protein 220316 yaeF 8214758 yaeF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076163.1 219492 R 544404 CDS YP_003076164.1 254791327 8214759 complement(220369..222087) 1 NC_013008.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 222087 proS 8214759 proS Escherichia coli O157:H7 str. TW14359 prolyl-tRNA synthetase YP_003076164.1 220369 R 544404 CDS YP_003076165.1 254791328 8214760 complement(222198..222905) 1 NC_013008.1 hypothetical protein 222905 yaeB 8214760 yaeB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076165.1 222198 R 544404 CDS YP_003076166.1 254791329 8214761 complement(222902..223306) 1 NC_013008.1 outer membrane lipoprotein 223306 rcsF 8214761 rcsF Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003076166.1 222902 R 544404 CDS YP_003076167.1 254791330 8214762 complement(223424..224239) 1 NC_013008.1 DL-methionine transporter substrate-binding subunit 224239 metQ 8214762 metQ Escherichia coli O157:H7 str. TW14359 DL-methionine transporter substrate-binding subunit YP_003076167.1 223424 R 544404 CDS YP_003076168.1 254791331 8214763 complement(224279..224932) 1 NC_013008.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit 224932 metI 8214763 metI Escherichia coli O157:H7 str. TW14359 DL-methionine transporter permease subunit YP_003076168.1 224279 R 544404 CDS YP_003076169.1 254791332 8214764 complement(224925..225956) 1 NC_013008.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 225956 metN 8214764 metN Escherichia coli O157:H7 str. TW14359 DL-methionine transporter ATP-binding subunit YP_003076169.1 224925 R 544404 CDS YP_003076170.1 254791333 8214765 226144..226719 1 NC_013008.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 226719 gmhB 8214765 gmhB Escherichia coli O157:H7 str. TW14359 D,D-heptose 1,7-bisphosphate phosphatase YP_003076170.1 226144 D 544404 CDS YP_003076171.1 254791334 8214772 232479..233282 1 NC_013008.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 233282 dkgB 8214772 dkgB Escherichia coli O157:H7 str. TW14359 2,5-diketo-D-gluconate reductase B YP_003076171.1 232479 D 544404 CDS YP_003076172.1 254791335 8214773 complement(233279..234193) 1 NC_013008.1 DNA-binding transcriptional regulator 234193 yafC 8214773 yafC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076172.1 233279 R 544404 CDS YP_003076173.1 254791336 8214774 234434..235234 1 NC_013008.1 hypothetical protein 235234 yafD 8214774 yafD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076173.1 234434 D 544404 CDS YP_003076174.1 254791337 8214775 235312..236082 1 NC_013008.1 SAM-dependent methyltransferase 236082 yafE 8214775 yafE Escherichia coli O157:H7 str. TW14359 SAM-dependent methyltransferase YP_003076174.1 235312 D 544404 CDS YP_003076175.1 254791338 8214776 complement(236130..237488) 1 NC_013008.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 237488 mltD 8214776 mltD Escherichia coli O157:H7 str. TW14359 membrane-bound lytic murein transglycosylase D YP_003076175.1 236130 R 544404 CDS YP_003076176.1 254791339 8214777 complement(237560..238315) 1 NC_013008.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 238315 gloB 8214777 gloB Escherichia coli O157:H7 str. TW14359 hydroxyacylglutathione hydrolase YP_003076176.1 237560 R 544404 CDS YP_003076177.1 254791340 8214778 238349..239071 1 NC_013008.1 S-adenosyl-L-methionine-dependent methyltransferase 239071 yafS 8214778 yafS Escherichia coli O157:H7 str. TW14359 S-adenosyl-L-methionine-dependent methyltransferase YP_003076177.1 238349 D 544404 CDS YP_003076178.1 254791341 8214779 complement(239068..239535) 1 NC_013008.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 239535 rnhA 8214779 rnhA Escherichia coli O157:H7 str. TW14359 ribonuclease H YP_003076178.1 239068 R 544404 CDS YP_003076179.1 254791342 8214780 239600..240331 1 NC_013008.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 240331 dnaQ 8214780 dnaQ Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit epsilon YP_003076179.1 239600 D 544404 CDS YP_003076180.1 254791343 8214782 240869..241669 1 NC_013008.1 aminopeptidase 241669 yafT 8214782 yafT Escherichia coli O157:H7 str. TW14359 aminopeptidase YP_003076180.1 240869 D 544404 CDS YP_003076181.1 254791344 8214783 complement(241854..242150) 1 NC_013008.1 hypothetical protein 242150 8214783 ECSP_0217 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076181.1 241854 R 544404 CDS YP_003076182.1 254791345 8214784 complement(242147..242602) 1 NC_013008.1 hypothetical protein 242602 8214784 ECSP_0218 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076182.1 242147 R 544404 CDS YP_003076183.1 254791346 8214785 complement(242599..243195) 1 NC_013008.1 hypothetical protein 243195 8214785 ECSP_0219 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076183.1 242599 R 544404 CDS YP_003076184.1 254791347 8214786 complement(243305..243496) 1 NC_013008.1 hypothetical protein 243496 8214786 ECSP_0220 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076184.1 243305 R 544404 CDS YP_003076185.1 254791348 8214787 complement(243517..243996) 1 NC_013008.1 hypothetical protein 243996 8214787 ECSP_0221 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076185.1 243517 R 544404 CDS YP_003076186.1 254791349 8214788 complement(243962..245461) 1 NC_013008.1 hypothetical protein 245461 8214788 ECSP_0222 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076186.1 243962 R 544404 CDS YP_003076187.1 254791350 8214789 complement(245382..248816) 1 NC_013008.1 macrophage toxin 248816 8214789 ECSP_0223 Escherichia coli O157:H7 str. TW14359 macrophage toxin YP_003076187.1 245382 R 544404 CDS YP_003076188.1 254791351 8214790 complement(248953..250365) 1 NC_013008.1 ImpA domain-containing protein 250365 8214790 ECSP_0224 Escherichia coli O157:H7 str. TW14359 ImpA domain-containing protein YP_003076188.1 248953 R 544404 CDS YP_003076189.1 254791352 8214791 complement(250370..251113) 1 NC_013008.1 hypothetical protein 251113 8214791 ECSP_0225 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076189.1 250370 R 544404 CDS YP_003076190.1 254791353 8214792 complement(251110..253887) 1 NC_013008.1 Hsp100/Clp ATPase 253887 clpV 8214792 clpV Escherichia coli O157:H7 str. TW14359 Hsp100/Clp ATPase YP_003076190.1 251110 R 544404 CDS YP_003076191.1 254791354 8214793 complement(253896..254657) 1 NC_013008.1 hypothetical protein 254657 8214793 ECSP_0227 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076191.1 253896 R 544404 CDS YP_003076192.1 254791355 8214794 complement(254662..255993) 1 NC_013008.1 hypothetical protein 255993 8214794 ECSP_0228 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076192.1 254662 R 544404 CDS YP_003076193.1 254791356 8214795 complement(255996..256520) 1 NC_013008.1 hypothetical protein 256520 8214795 ECSP_0229 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076193.1 255996 R 544404 CDS YP_003076194.1 254791357 8214796 complement(256517..257818) 1 NC_013008.1 hypothetical protein 257818 8214796 ECSP_0230 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076194.1 256517 R 544404 CDS YP_003076195.1 254791358 8214797 complement(257822..258904) 1 NC_013008.1 hypothetical protein 258904 8214797 ECSP_0231 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076195.1 257822 R 544404 CDS YP_003076196.1 254791359 8214798 complement(258868..260718) 1 NC_013008.1 hypothetical protein 260718 8214798 ECSP_0232 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076196.1 258868 R 544404 CDS YP_003076197.1 254791360 8214799 complement(260722..261135) 1 NC_013008.1 hypothetical protein 261135 8214799 ECSP_0233 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076197.1 260722 R 544404 CDS YP_003076198.1 254791361 8214800 complement(261226..262617) 1 NC_013008.1 hypothetical protein 262617 8214800 ECSP_0234 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076198.1 261226 R 544404 CDS YP_003076199.1 254791362 8214801 complement(262668..262892) 1 NC_013008.1 hypothetical protein 262892 8214801 ECSP_0235 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076199.1 262668 R 544404 CDS YP_003076200.1 254791363 8214802 complement(262927..263427) 1 NC_013008.1 hypothetical protein 263427 8214802 ECSP_0236 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076200.1 262927 R 544404 CDS YP_003076201.1 254791364 8214803 263854..263997 1 NC_013008.1 hypothetical protein 263997 8214803 ECSP_0237 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076201.1 263854 D 544404 CDS YP_003076202.1 254791365 8214804 264124..264642 1 NC_013008.1 hypothetical protein 264642 8214804 ECSP_0238 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076202.1 264124 D 544404 CDS YP_003076203.1 254791366 8214805 264675..264812 1 NC_013008.1 hypothetical protein 264812 8214805 ECSP_0239 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076203.1 264675 D 544404 CDS YP_003076204.1 254791367 8214806 264852..266993 1 NC_013008.1 hypothetical protein 266993 8214806 ECSP_0240 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076204.1 264852 D 544404 CDS YP_003076205.1 254791368 8214807 267069..271301 1 NC_013008.1 hypothetical protein 271301 8214807 ECSP_0241 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076205.1 267069 D 544404 CDS YP_003076206.1 254791369 8214808 271408..272157 1 NC_013008.1 ankyrin repeat containing virulence factor 272157 8214808 ECSP_0242 Escherichia coli O157:H7 str. TW14359 ankyrin repeat containing virulence factor YP_003076206.1 271408 D 544404 CDS YP_003076207.1 254791370 8214809 272339..273847 1 NC_013008.1 RhsG core protein 273847 8214809 ECSP_0243 Escherichia coli O157:H7 str. TW14359 RhsG core protein YP_003076207.1 272339 D 544404 CDS YP_003076208.1 254791371 8214810 273850..274467 1 NC_013008.1 hypothetical protein 274467 8214810 ECSP_0244 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076208.1 273850 D 544404 CDS YP_003076209.1 254791372 8214811 complement(274470..274616) 1 NC_013008.1 hypothetical protein 274616 8214811 ECSP_0245 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076209.1 274470 R 544404 CDS YP_003076210.1 254791373 8214812 274806..275105 1 NC_013008.1 hypothetical protein 275105 8214812 ECSP_0246 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076210.1 274806 D 544404 CDS YP_003076211.1 254791374 8214813 275213..276349 1 NC_013008.1 transposase 276349 8214813 ECSP_0247 Escherichia coli O157:H7 str. TW14359 transposase YP_003076211.1 275213 D 544404 CDS YP_003076212.1 254791375 8214814 276352..278112 1 NC_013008.1 hypothetical protein 278112 8214814 ECSP_0248 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076212.1 276352 D 544404 CDS YP_003076213.1 254791376 8214815 278314..278577 1 NC_013008.1 hypothetical protein 278577 8214815 ECSP_0249 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076213.1 278314 D 544404 CDS YP_003076214.1 254791377 8214816 278758..279930 1 NC_013008.1 hypothetical protein 279930 8214816 ECSP_0250 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076214.1 278758 D 544404 CDS YP_003076215.1 254791378 8214817 complement(280048..280818) 1 NC_013008.1 hypothetical protein 280818 yafV 8214817 yafV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076215.1 280048 R 544404 CDS YP_003076216.1 254791379 8214818 280972..281445 1 NC_013008.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 281445 ivy 8214818 ivy Escherichia coli O157:H7 str. TW14359 C-lysozyme inhibitor YP_003076216.1 280972 D 544404 CDS YP_003076217.1 254791380 8214819 complement(281488..283932) 1 NC_013008.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 283932 fadE 8214819 fadE Escherichia coli O157:H7 str. TW14359 acyl-CoA dehydrogenase YP_003076217.1 281488 R 544404 CDS YP_003076218.1 254791381 8214820 284172..284750 1 NC_013008.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 284750 gmhA 8214820 gmhA Escherichia coli O157:H7 str. TW14359 phosphoheptose isomerase YP_003076218.1 284172 D 544404 CDS YP_003076219.1 254791382 8214821 284855..285622 1 NC_013008.1 amidotransfease 285622 yafJ 8214821 yafJ Escherichia coli O157:H7 str. TW14359 amidotransfease YP_003076219.1 284855 D 544404 CDS YP_003076220.1 254791383 8214822 complement(285593..286333) 1 NC_013008.1 hypothetical protein 286333 yafK 8214822 yafK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076220.1 285593 R 544404 CDS YP_003076221.1 254791384 8214823 complement(286489..286749) 1 NC_013008.1 hypothetical protein 286749 8214823 ECSP_0257 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076221.1 286489 R 544404 CDS YP_003076222.1 254791385 8214824 complement(286768..287028) 1 NC_013008.1 antitoxin of YafQ-DinJ toxin-antitoxin system 287028 dinJ 8214824 dinJ Escherichia coli O157:H7 str. TW14359 antitoxin of YafQ-DinJ toxin-antitoxin system YP_003076222.1 286768 R 544404 CDS YP_003076223.1 254791386 8214825 287238..287987 1 NC_013008.1 lipoprotein and C40 family peptidase 287987 yafL 8214825 yafL Escherichia coli O157:H7 str. TW14359 lipoprotein and C40 family peptidase YP_003076223.1 287238 D 544404 CDS YP_003076224.1 254791387 8214826 288163..288459 1 NC_013008.1 hypothetical protein 288459 yafM 8214826 yafM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076224.1 288163 D 544404 CDS YP_003076225.1 254791388 8214828 288678..288797 1 NC_013008.1 hypothetical protein 288797 8214828 ECSP_0262 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076225.1 288678 D 544404 CDS YP_003076226.1 254791389 8214829 complement(288805..290544) 1 NC_013008.1 Flagellar component 290544 8214829 ECSP_0263 Escherichia coli O157:H7 str. TW14359 Flagellar component YP_003076226.1 288805 R 544404 CDS YP_003076227.1 254791390 8214830 290504..291274 1 NC_013008.1 hypothetical protein 291274 8214830 ECSP_0264 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076227.1 290504 D 544404 CDS YP_003076228.1 254791391 8214831 291345..292400 1 NC_013008.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 292400 dinB 8214831 dinB Escherichia coli O157:H7 str. TW14359 DNA polymerase IV YP_003076228.1 291345 D 544404 CDS YP_003076229.1 254791392 8214832 292452..292745 1 NC_013008.1 antitoxin of the YafO-YafN toxin-antitoxin system 292745 yafN 8214832 yafN Escherichia coli O157:H7 str. TW14359 antitoxin of the YafO-YafN toxin-antitoxin system YP_003076229.1 292452 D 544404 CDS YP_003076230.1 254791393 8214833 292748..293146 1 NC_013008.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 293146 yafO 8214833 yafO Escherichia coli O157:H7 str. TW14359 toxin YafO YP_003076230.1 292748 D 544404 CDS YP_003076231.1 254791394 8214834 293156..293608 1 NC_013008.1 hypothetical protein 293608 yafP 8214834 yafP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076231.1 293156 D 544404 CDS YP_003076232.1 254791395 8214835 293927..294181 1 NC_013008.1 hypothetical protein 294181 8214835 ECSP_0269 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076232.1 293927 D 544404 CDS YP_003076233.1 254791396 8214836 294150..294650 1 NC_013008.1 similar to release factor 1 and 2; peptide chain release factor-like protein 294650 prfH 8214836 prfH Escherichia coli O157:H7 str. TW14359 peptide chain release factor-like protein YP_003076233.1 294150 D 544404 CDS YP_003076234.1 254791397 8214837 complement(294707..296164) 1 NC_013008.1 aminoacyl-histidine dipeptidase 296164 pepD 8214837 pepD Escherichia coli O157:H7 str. TW14359 aminoacyl-histidine dipeptidase YP_003076234.1 294707 R 544404 CDS YP_003076235.1 254791398 8214838 296425..296883 1 NC_013008.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 296883 gpt 8214838 gpt Escherichia coli O157:H7 str. TW14359 xanthine-guanine phosphoribosyltransferase YP_003076235.1 296425 D 544404 CDS YP_003076236.1 254791399 8214839 296975..298219 1 NC_013008.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 298219 frsA 8214839 frsA Escherichia coli O157:H7 str. TW14359 fermentation/respiration switch protein YP_003076236.1 296975 D 544404 CDS YP_003076237.1 254791400 8214840 298277..298678 1 NC_013008.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 298678 crl 8214840 crl Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator Crl YP_003076237.1 298277 D 544404 CDS YP_003076238.1 254791401 8214841 complement(298717..299772) 1 NC_013008.1 outer membrane phosphoporin protein E 299772 phoE 8214841 phoE Escherichia coli O157:H7 str. TW14359 outer membrane phosphoporin protein E YP_003076238.1 298717 R 544404 CDS YP_003076239.1 254791402 8214842 300060..301163 1 NC_013008.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 301163 proB 8214842 proB Escherichia coli O157:H7 str. TW14359 gamma-glutamyl kinase YP_003076239.1 300060 D 544404 CDS YP_003076240.1 254791403 8214843 301175..302428 1 NC_013008.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 302428 proA 8214843 proA Escherichia coli O157:H7 str. TW14359 gamma-glutamyl phosphate reductase YP_003076240.1 301175 D 544404 CDS YP_003076241.1 254791404 8214845 complement(302633..303607) 1 NC_013008.1 integrase for prophage CP-933H 303607 intH 8214845 intH Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933H YP_003076241.1 302633 R 544404 CDS YP_003076242.1 254791405 8214846 complement(304070..304960) 1 NC_013008.1 transposase 304960 8214846 ECSP_0280 Escherichia coli O157:H7 str. TW14359 transposase YP_003076242.1 304070 R 544404 CDS YP_003076243.1 254791406 8214847 complement(304957..305283) 1 NC_013008.1 transposase 305283 8214847 ECSP_0281 Escherichia coli O157:H7 str. TW14359 transposase YP_003076243.1 304957 R 544404 CDS YP_003076244.1 254791407 8214848 complement(305309..305692) 1 NC_013008.1 hypothetical protein 305692 8214848 ECSP_0282 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076244.1 305309 R 544404 CDS YP_003076245.1 254791408 8214849 complement(305820..306533) 1 NC_013008.1 cI repressor protein for prophage CP-933H 306533 8214849 ECSP_0283 Escherichia coli O157:H7 str. TW14359 cI repressor protein for prophage CP-933H YP_003076245.1 305820 R 544404 CDS YP_003076246.1 254791409 8214850 306634..306834 1 NC_013008.1 regulatory protein cro 306834 8214850 ECSP_0284 Escherichia coli O157:H7 str. TW14359 regulatory protein cro YP_003076246.1 306634 D 544404 CDS YP_003076247.1 254791410 8214851 306953..307246 1 NC_013008.1 cII antiterminator protein for prophage CP-933H 307246 8214851 ECSP_0285 Escherichia coli O157:H7 str. TW14359 cII antiterminator protein for prophage CP-933H YP_003076247.1 306953 D 544404 CDS YP_003076248.1 254791411 8214853 308198..308509 1 NC_013008.1 replication protein P for prophage CP-933H 308509 8214853 ECSP_0287 Escherichia coli O157:H7 str. TW14359 replication protein P for prophage CP-933H YP_003076248.1 308198 D 544404 CDS YP_003076249.1 254791412 8214854 308509..309303 1 NC_013008.1 tail fiber protein from prophage CP-933H 309303 8214854 ECSP_0288 Escherichia coli O157:H7 str. TW14359 tail fiber protein from prophage CP-933H YP_003076249.1 308509 D 544404 CDS YP_003076250.1 254791413 8214855 309303..309896 1 NC_013008.1 hypothetical protein 309896 8214855 ECSP_0289 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076250.1 309303 D 544404 CDS YP_003076251.1 254791414 8214856 complement(309868..310320) 1 NC_013008.1 hypothetical protein 310320 8214856 ECSP_0290 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076251.1 309868 R 544404 CDS YP_003076252.1 254791415 8214857 complement(310332..310766) 1 NC_013008.1 hypothetical protein 310766 8214857 ECSP_0291 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076252.1 310332 R 544404 CDS YP_003076253.1 254791416 8214858 310772..311326 1 NC_013008.1 DNA invertase from prophage CP-933H 311326 pinH 8214858 pinH Escherichia coli O157:H7 str. TW14359 DNA invertase from prophage CP-933H YP_003076253.1 310772 D 544404 CDS YP_003076254.1 254791417 8214859 complement(311384..312157) 1 NC_013008.1 hypothetical protein 312157 8214859 ECSP_0293 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076254.1 311384 R 544404 CDS YP_003076255.1 254791418 8214860 312980..313723 1 NC_013008.1 AraC family transcriptional regulator 313723 8214860 ECSP_0294 Escherichia coli O157:H7 str. TW14359 AraC family transcriptional regulator YP_003076255.1 312980 D 544404 CDS YP_003076256.1 254791419 8214861 complement(313765..314130) 1 NC_013008.1 hypothetical protein 314130 8214861 ECSP_0295 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076256.1 313765 R 544404 CDS YP_003076257.1 254791420 8214862 complement(315248..316138) 1 NC_013008.1 transposase 316138 8214862 ECSP_0296 Escherichia coli O157:H7 str. TW14359 transposase YP_003076257.1 315248 R 544404 CDS YP_003076258.1 254791421 8214863 complement(316135..316461) 1 NC_013008.1 transposase 316461 8214863 ECSP_0297 Escherichia coli O157:H7 str. TW14359 transposase YP_003076258.1 316135 R 544404 CDS YP_003076259.1 254791422 8214866 318190..318648 1 NC_013008.1 hypothetical protein 318648 8214866 ECSP_0300 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076259.1 318190 D 544404 CDS YP_003076260.1 254791423 8214867 318641..319273 1 NC_013008.1 hypothetical protein 319273 8214867 ECSP_0301 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076260.1 318641 D 544404 CDS YP_003076261.1 254791424 8214868 319304..319693 1 NC_013008.1 hypothetical protein 319693 8214868 ECSP_0302 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076261.1 319304 D 544404 CDS YP_003076262.1 254791425 8214869 319893..320459 1 NC_013008.1 hypothetical protein 320459 8214869 ECSP_0303 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076262.1 319893 D 544404 CDS YP_003076263.1 254791426 8214870 complement(320869..321141) 1 NC_013008.1 activator encoded in prophage CP-933I 321141 8214870 ECSP_0304 Escherichia coli O157:H7 str. TW14359 activator encoded in prophage CP-933I YP_003076263.1 320869 R 544404 CDS YP_003076264.1 254791427 8214871 complement(321147..321698) 1 NC_013008.1 polarity suppression protein encoded in CP-933I 321698 psuI 8214871 psuI Escherichia coli O157:H7 str. TW14359 polarity suppression protein encoded in CP-933I YP_003076264.1 321147 R 544404 CDS YP_003076265.1 254791428 8214872 complement(321695..322447) 1 NC_013008.1 capsid morphogenesis protein encoded in CP-933I 322447 sidI 8214872 sidI Escherichia coli O157:H7 str. TW14359 capsid morphogenesis protein encoded in CP-933I YP_003076265.1 321695 R 544404 CDS YP_003076266.1 254791429 8214873 322850..323020 1 NC_013008.1 hypothetical protein 323020 8214873 ECSP_0307 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076266.1 322850 D 544404 CDS YP_003076267.1 254791430 8214874 323381..323641 1 NC_013008.1 regulatory protein encoded in prophage CP-933I 323641 8214874 ECSP_0308 Escherichia coli O157:H7 str. TW14359 regulatory protein encoded in prophage CP-933I YP_003076267.1 323381 D 544404 CDS YP_003076268.1 254791431 8214875 323638..324195 1 NC_013008.1 regulator encoded in prophage CP-933I 324195 8214875 ECSP_0309 Escherichia coli O157:H7 str. TW14359 regulator encoded in prophage CP-933I YP_003076268.1 323638 D 544404 CDS YP_003076269.1 254791432 8214876 324413..324736 1 NC_013008.1 hypothetical protein 324736 8214876 ECSP_0310 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076269.1 324413 D 544404 CDS YP_003076270.1 254791433 8214877 324750..327083 1 NC_013008.1 alpha replication protein of prophage CP-933I 327083 8214877 ECSP_0311 Escherichia coli O157:H7 str. TW14359 alpha replication protein of prophage CP-933I YP_003076270.1 324750 D 544404 CDS YP_003076271.1 254791434 8214878 complement(327216..328172) 1 NC_013008.1 hypothetical protein 328172 8214878 ECSP_0312 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076271.1 327216 R 544404 CDS YP_003076272.1 254791435 8214879 complement(328848..329747) 1 NC_013008.1 LysR family transcriptional regulator 329747 8214879 ECSP_0313 Escherichia coli O157:H7 str. TW14359 LysR family transcriptional regulator YP_003076272.1 328848 R 544404 CDS YP_003076273.1 254791436 8214880 329846..330568 1 NC_013008.1 oxidoreductase 330568 8214880 ECSP_0314 Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076273.1 329846 D 544404 CDS YP_003076274.1 254791437 8214881 330735..331013 1 NC_013008.1 hypothetical protein 331013 8214881 ECSP_0315 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076274.1 330735 D 544404 CDS YP_003076275.1 254791438 8214882 331288..331437 1 NC_013008.1 hypothetical protein 331437 8214882 ECSP_0316 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076275.1 331288 D 544404 CDS YP_003076276.1 254791439 8214883 complement(331716..332600) 1 NC_013008.1 LysR family transcriptional regulator 332600 8214883 ECSP_0317 Escherichia coli O157:H7 str. TW14359 LysR family transcriptional regulator YP_003076276.1 331716 R 544404 CDS YP_003076277.1 254791440 8214884 332864..333922 1 NC_013008.1 hypothetical protein 333922 8214884 ECSP_0318 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076277.1 332864 D 544404 CDS YP_003076278.1 254791441 8214885 333998..335191 1 NC_013008.1 transcriptional regulator 335191 8214885 ECSP_0319 Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003076278.1 333998 D 544404 CDS YP_003076279.1 254791442 8214886 complement(335370..336326) 1 NC_013008.1 hypothetical protein 336326 yagQ 8214886 yagQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076279.1 335370 R 544404 CDS YP_003076280.1 254791443 8214887 complement(336336..338534) 1 NC_013008.1 oxidoreductase 338534 yagR 8214887 yagR Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076280.1 336336 R 544404 CDS YP_003076281.1 254791444 8214888 complement(338531..339487) 1 NC_013008.1 oxidoreductase 339487 yagS 8214888 yagS Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076281.1 338531 R 544404 CDS YP_003076282.1 254791445 8214889 complement(339484..340173) 1 NC_013008.1 xanthine dehydrogenase iron-sulfur-binding subunit 340173 yagT 8214889 yagT Escherichia coli O157:H7 str. TW14359 xanthine dehydrogenase iron-sulfur-binding subunit YP_003076282.1 339484 R 544404 CDS YP_003076283.1 254791446 8214890 340591..341205 1 NC_013008.1 hypothetical protein 341205 yagU 8214890 yagU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076283.1 340591 D 544404 CDS YP_003076284.1 254791447 8214891 complement(341453..341782) 1 NC_013008.1 ferredoxin 341782 ykgJ 8214891 ykgJ Escherichia coli O157:H7 str. TW14359 ferredoxin YP_003076284.1 341453 R 544404 CDS YP_003076285.1 254791448 8214892 complement(342095..342805) 1 NC_013008.1 chaperone 342805 ecpE 8214892 ecpE Escherichia coli O157:H7 str. TW14359 chaperone YP_003076285.1 342095 R 544404 CDS YP_003076286.1 254791449 8214893 complement(342774..344417) 1 NC_013008.1 receptor 344417 yagW 8214893 yagW Escherichia coli O157:H7 str. TW14359 receptor YP_003076286.1 342774 R 544404 CDS YP_003076287.1 254791450 8214894 complement(344407..346932) 1 NC_013008.1 usher protein 346932 ecpC 8214894 ecpC Escherichia coli O157:H7 str. TW14359 usher protein YP_003076287.1 344407 R 544404 CDS YP_003076288.1 254791451 8214895 complement(346958..347626) 1 NC_013008.1 chaperone 347626 ecpB 8214895 ecpB Escherichia coli O157:H7 str. TW14359 chaperone YP_003076288.1 346958 R 544404 CDS YP_003076289.1 254791452 8214896 complement(347684..348271) 1 NC_013008.1 Mat fimbrillin 348271 ecpA 8214896 ecpA Escherichia coli O157:H7 str. TW14359 Mat fimbrillin YP_003076289.1 347684 R 544404 CDS YP_003076290.1 254791453 8214897 complement(348346..348936) 1 NC_013008.1 regulator 348936 ecpR 8214897 ecpR Escherichia coli O157:H7 str. TW14359 regulator YP_003076290.1 348346 R 544404 CDS YP_003076291.1 254791454 8214898 complement(349135..349230) 1 NC_013008.1 hypothetical protein 349230 8214898 ECSP_0332 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076291.1 349135 R 544404 CDS YP_003076292.1 254791455 8214899 complement(349342..349566) 1 NC_013008.1 hypothetical protein 349566 8214899 ECSP_0333 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076292.1 349342 R 544404 CDS YP_003076293.1 254791456 8214900 349713..349904 1 NC_013008.1 hypothetical protein 349904 ykgL 8214900 ykgL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076293.1 349713 D 544404 CDS YP_003076294.1 254791457 8214901 complement(349974..350114) 1 NC_013008.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 350114 rpmJ 8214901 rpmJ Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L36 YP_003076294.1 349974 R 544404 CDS YP_003076295.1 254791458 8214902 complement(350114..350377) 1 NC_013008.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 350377 rpmE2 8214902 rpmE2 Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L31 YP_003076295.1 350114 R 544404 CDS YP_003076296.1 254791459 8214903 350620..351021 1 NC_013008.1 hypothetical protein 351021 8214903 ECSP_0337 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076296.1 350620 D 544404 CDS YP_003076297.1 254791460 8214904 351018..351365 1 NC_013008.1 transposase ISEc8 351365 8214904 ECSP_0338 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003076297.1 351018 D 544404 CDS YP_003076298.1 254791461 8214905 351415..352953 1 NC_013008.1 transposase ISEc8 352953 8214905 ECSP_0339 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003076298.1 351415 D 544404 CDS YP_003076299.1 254791462 8214906 complement(353765..354907) 1 NC_013008.1 oxidoreductase 354907 8214906 ECSP_0340 Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076299.1 353765 R 544404 CDS YP_003076300.1 254791463 8214907 complement(355142..356062) 1 NC_013008.1 hypothetical protein 356062 8214907 ECSP_0341 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076300.1 355142 R 544404 CDS YP_003076301.1 254791464 8214908 356156..357145 1 NC_013008.1 LysR family transcriptional regulator 357145 8214908 ECSP_0342 Escherichia coli O157:H7 str. TW14359 LysR family transcriptional regulator YP_003076301.1 356156 D 544404 CDS YP_003076302.1 254791465 8214909 complement(357433..357789) 1 NC_013008.1 hypothetical protein 357789 8214909 ECSP_0343 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076302.1 357433 R 544404 CDS YP_003076303.1 254791466 8214910 357820..357948 1 NC_013008.1 hypothetical protein 357948 8214910 ECSP_0344 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076303.1 357820 D 544404 CDS YP_003076304.1 254791467 8214911 complement(357982..358557) 1 NC_013008.1 hypothetical protein 358557 8214911 ECSP_0345 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076304.1 357982 R 544404 CDS YP_003076305.1 254791468 8214912 359123..363376 1 NC_013008.1 adhesin 363376 eaeH 8214912 eaeH Escherichia coli O157:H7 str. TW14359 adhesin YP_003076305.1 359123 D 544404 CDS YP_003076306.1 254791469 8214913 complement(363497..364387) 1 NC_013008.1 DNA-binding transcriptional regulator 364387 ykgA 8214913 ykgA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076306.1 363497 R 544404 CDS YP_003076307.1 254791470 8214914 364603..365472 1 NC_013008.1 dehydrogenase 365472 8214914 ECSP_0348 Escherichia coli O157:H7 str. TW14359 dehydrogenase YP_003076307.1 364603 D 544404 CDS YP_003076308.1 254791471 8214915 complement(365632..366225) 1 NC_013008.1 hypothetical protein 366225 ykgB 8214915 ykgB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076308.1 365632 R 544404 CDS YP_003076309.1 254791472 8214916 complement(366237..366473) 1 NC_013008.1 hypothetical protein 366473 ykgI 8214916 ykgI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076309.1 366237 R 544404 CDS YP_003076310.1 254791473 8214917 complement(366582..367907) 1 NC_013008.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 367907 ykgC 8214917 ykgC Escherichia coli O157:H7 str. TW14359 pyridine nucleotide-disulfide oxidoreductase YP_003076310.1 366582 R 544404 CDS YP_003076311.1 254791474 8214918 368133..368987 1 NC_013008.1 DNA-binding transcriptional regulator 368987 ykgD 8214918 ykgD Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076311.1 368133 D 544404 CDS YP_003076312.1 254791475 8214919 369514..370233 1 NC_013008.1 oxidoreductase 370233 ykgE 8214919 ykgE Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076312.1 369514 D 544404 CDS YP_003076313.1 254791476 8214920 370244..371671 1 NC_013008.1 amino acid dehydrogenase 371671 ykgF 8214920 ykgF Escherichia coli O157:H7 str. TW14359 amino acid dehydrogenase YP_003076313.1 370244 D 544404 CDS YP_003076314.1 254791477 8214921 371664..372359 1 NC_013008.1 transporter 372359 ykgG 8214921 ykgG Escherichia coli O157:H7 str. TW14359 transporter YP_003076314.1 371664 D 544404 CDS YP_003076315.1 254791478 8214922 complement(372433..372630) 1 NC_013008.1 hypothetical protein 372630 8214922 ECSP_0356 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076315.1 372433 R 544404 CDS YP_003076316.1 254791479 8214925 complement(373618..374712) 1 NC_013008.1 autotransporter 374712 8214925 ECSP_0359 Escherichia coli O157:H7 str. TW14359 autotransporter YP_003076316.1 373618 R 544404 CDS YP_003076317.1 254791480 8214926 complement(374754..375515) 1 NC_013008.1 hypothetical protein 375515 8214926 ECSP_0360 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076317.1 374754 R 544404 CDS YP_003076318.1 254791481 8214927 complement(375669..376253) 1 NC_013008.1 hypothetical protein 376253 8214927 ECSP_0361 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076318.1 375669 R 544404 CDS YP_003076319.1 254791482 8214928 complement(376345..376482) 1 NC_013008.1 hypothetical protein 376482 8214928 ECSP_0362 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076319.1 376345 R 544404 CDS YP_003076320.1 254791483 8214930 377599..377733 1 NC_013008.1 hypothetical protein 377733 8214930 ECSP_0364 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076320.1 377599 D 544404 CDS YP_003076321.1 254791484 8214931 378162..378413 1 NC_013008.1 hypothetical protein 378413 8214931 ECSP_0365 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076321.1 378162 D 544404 CDS YP_003076322.1 254791485 8214932 complement(378415..380103) 1 NC_013008.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 380103 betA 8214932 betA Escherichia coli O157:H7 str. TW14359 choline dehydrogenase YP_003076322.1 378415 R 544404 CDS YP_003076323.1 254791486 8214933 complement(380117..381589) 1 NC_013008.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 381589 betB 8214933 betB Escherichia coli O157:H7 str. TW14359 betaine aldehyde dehydrogenase YP_003076323.1 380117 R 544404 CDS YP_003076324.1 254791487 8214934 complement(381603..382190) 1 NC_013008.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 382190 betI 8214934 betI Escherichia coli O157:H7 str. TW14359 transcriptional regulator BetI YP_003076324.1 381603 R 544404 CDS YP_003076325.1 254791488 8214935 382319..384352 1 NC_013008.1 proton-motive-force-driven choline transporter; choline transport protein BetT 384352 betT 8214935 betT Escherichia coli O157:H7 str. TW14359 choline transport protein BetT YP_003076325.1 382319 D 544404 CDS YP_003076326.1 254791489 8214936 384860..388909 1 NC_013008.1 beta-barrel outer membrane protein 388909 8214936 ECSP_0370 Escherichia coli O157:H7 str. TW14359 beta-barrel outer membrane protein YP_003076326.1 384860 D 544404 CDS YP_003076327.1 254791490 8214937 389051..390139 1 NC_013008.1 DNA-binding transcriptional regulator 390139 yahA 8214937 yahA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076327.1 389051 D 544404 CDS YP_003076328.1 254791491 8214939 complement(391204..391506) 1 NC_013008.1 hypothetical protein 391506 8214939 ECSP_0373 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076328.1 391204 R 544404 CDS YP_003076329.1 254791492 8214940 391969..392574 1 NC_013008.1 transcriptional regulator with ankyrin domain 392574 yahD 8214940 yahD Escherichia coli O157:H7 str. TW14359 transcriptional regulator with ankyrin domain YP_003076329.1 391969 D 544404 CDS YP_003076330.1 254791493 8214941 392614..393477 1 NC_013008.1 hypothetical protein 393477 yahE 8214941 yahE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076330.1 392614 D 544404 CDS YP_003076331.1 254791494 8214942 393467..395014 1 NC_013008.1 acyl-CoA synthetase with NAD(P)-binding domain and succinyl-CoA synthetase domain 395014 yahF 8214942 yahF Escherichia coli O157:H7 str. TW14359 acyl-CoA synthetase with NAD(P)-binding domain and succinyl-CoA synthetase domain YP_003076331.1 393467 D 544404 CDS YP_003076332.1 254791495 8214943 395014..396432 1 NC_013008.1 hypothetical protein 396432 yahG 8214943 yahG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076332.1 395014 D 544404 CDS YP_003076333.1 254791496 8214944 396451..396915 1 NC_013008.1 hypothetical protein 396915 8214944 ECSP_0378 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076333.1 396451 D 544404 CDS YP_003076334.1 254791497 8214945 396947..397897 1 NC_013008.1 carbamate kinase 397897 yahI 8214945 yahI Escherichia coli O157:H7 str. TW14359 carbamate kinase YP_003076334.1 396947 D 544404 CDS YP_003076335.1 254791498 8214946 397907..399289 1 NC_013008.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 399289 yahJ 8214946 yahJ Escherichia coli O157:H7 str. TW14359 deaminase YP_003076335.1 397907 D 544404 CDS YP_003076336.1 254791499 8214947 399588..399998 1 NC_013008.1 hypothetical protein 399998 8214947 ECSP_0381 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076336.1 399588 D 544404 CDS YP_003076337.1 254791500 8214948 complement(400026..400127) 1 NC_013008.1 hypothetical protein 400127 8214948 ECSP_0382 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076337.1 400026 R 544404 CDS YP_003076338.1 254791501 8214949 400249..401235 1 NC_013008.1 periplasmic binding protein, substrate ribose 401235 8214949 ECSP_0383 Escherichia coli O157:H7 str. TW14359 periplasmic binding protein, substrate ribose YP_003076338.1 400249 D 544404 CDS YP_003076339.1 254791502 8214950 401284..402768 1 NC_013008.1 carbohydrate uptake transporter-2 (CUT2) family protein 402768 8214950 ECSP_0384 Escherichia coli O157:H7 str. TW14359 carbohydrate uptake transporter-2 (CUT2) family protein YP_003076339.1 401284 D 544404 CDS YP_003076340.1 254791503 8214951 402761..403732 1 NC_013008.1 permease component of transport system, probably ribose specific 403732 8214951 ECSP_0385 Escherichia coli O157:H7 str. TW14359 permease component of transport system, probably ribose specific YP_003076340.1 402761 D 544404 CDS YP_003076341.1 254791504 8214952 403729..404685 1 NC_013008.1 permease component of transport system, probably ribose specific 404685 8214952 ECSP_0386 Escherichia coli O157:H7 str. TW14359 permease component of transport system, probably ribose specific YP_003076341.1 403729 D 544404 CDS YP_003076342.1 254791505 8214953 404772..405821 1 NC_013008.1 oxidoreductase 405821 yahK 8214953 yahK Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076342.1 404772 D 544404 CDS YP_003076343.1 254791506 8214954 406064..406879 1 NC_013008.1 hypothetical protein 406879 yahL 8214954 yahL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076343.1 406064 D 544404 CDS YP_003076344.1 254791507 8214956 complement(407557..408228) 1 NC_013008.1 neutral amino-acid efflux system 408228 yahN 8214956 yahN Escherichia coli O157:H7 str. TW14359 neutral amino-acid efflux system YP_003076344.1 407557 R 544404 CDS YP_003076345.1 254791508 8214957 408375..408650 1 NC_013008.1 hypothetical protein 408650 yahO 8214957 yahO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076345.1 408375 D 544404 CDS YP_003076346.1 254791509 8214958 complement(408748..410334) 1 NC_013008.1 DNA-binding transcriptional activator 410334 prpR 8214958 prpR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator YP_003076346.1 408748 R 544404 CDS YP_003076347.1 254791510 8214959 410573..411463 1 NC_013008.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 411463 prpB 8214959 prpB Escherichia coli O157:H7 str. TW14359 2-methylisocitrate lyase YP_003076347.1 410573 D 544404 CDS YP_003076348.1 254791511 8214960 411619..412788 1 NC_013008.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 412788 prpC 8214960 prpC Escherichia coli O157:H7 str. TW14359 methylcitrate synthase YP_003076348.1 411619 D 544404 CDS YP_003076349.1 254791512 8214961 412822..414273 1 NC_013008.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 414273 prpD 8214961 prpD Escherichia coli O157:H7 str. TW14359 2-methylcitrate dehydratase YP_003076349.1 412822 D 544404 CDS YP_003076350.1 254791513 8214962 414313..416199 1 NC_013008.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 416199 prpE 8214962 prpE Escherichia coli O157:H7 str. TW14359 propionyl-CoA synthetase YP_003076350.1 414313 D 544404 CDS YP_003076351.1 254791514 8214963 complement(416468..416746) 1 NC_013008.1 hypothetical protein 416746 8214963 ECSP_0397 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076351.1 416468 R 544404 CDS YP_003076352.1 254791515 8214964 417093..418352 1 NC_013008.1 cytosine permease 418352 codB 8214964 codB Escherichia coli O157:H7 str. TW14359 cytosine permease YP_003076352.1 417093 D 544404 CDS YP_003076353.1 254791516 8214965 418342..419625 1 NC_013008.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 419625 codA 8214965 codA Escherichia coli O157:H7 str. TW14359 cytosine deaminase YP_003076353.1 418342 D 544404 CDS YP_003076354.1 254791517 8214966 complement(419758..420657) 1 NC_013008.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR 420657 cynR 8214966 cynR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator CynR YP_003076354.1 419758 R 544404 CDS YP_003076355.1 254791518 8214967 420767..421426 1 NC_013008.1 carbonic anhydrase 421426 cynT 8214967 cynT Escherichia coli O157:H7 str. TW14359 carbonic anhydrase YP_003076355.1 420767 D 544404 CDS YP_003076356.1 254791519 8214968 421457..421927 1 NC_013008.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 421927 cynS 8214968 cynS Escherichia coli O157:H7 str. TW14359 cyanate hydratase YP_003076356.1 421457 D 544404 CDS YP_003076357.1 254791520 8214969 421960..423114 1 NC_013008.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; cyanate transporter 423114 cynX 8214969 cynX Escherichia coli O157:H7 str. TW14359 cyanate transporter YP_003076357.1 421960 D 544404 CDS YP_003076358.1 254791521 8214970 complement(423217..423828) 1 NC_013008.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 423828 lacA 8214970 lacA Escherichia coli O157:H7 str. TW14359 galactoside O-acetyltransferase YP_003076358.1 423217 R 544404 CDS YP_003076359.1 254791522 8214971 complement(423894..425147) 1 NC_013008.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 425147 lacY 8214971 lacY Escherichia coli O157:H7 str. TW14359 galactoside permease YP_003076359.1 423894 R 544404 CDS YP_003076360.1 254791523 8214972 complement(425199..428273) 1 NC_013008.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 428273 lacZ 8214972 lacZ Escherichia coli O157:H7 str. TW14359 beta-D-galactosidase YP_003076360.1 425199 R 544404 CDS YP_003076361.1 254791524 8214973 complement(428396..429478) 1 NC_013008.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 429478 lacI 8214973 lacI Escherichia coli O157:H7 str. TW14359 lac repressor YP_003076361.1 428396 R 544404 CDS YP_003076362.1 254791525 8214974 complement(429515..430468) 1 NC_013008.1 AraC family transcriptional regulator 430468 8214974 ECSP_0408 Escherichia coli O157:H7 str. TW14359 AraC family transcriptional regulator YP_003076362.1 429515 R 544404 CDS YP_003076363.1 254791526 8214975 complement(430488..431264) 1 NC_013008.1 hypothetical protein 431264 8214975 ECSP_0409 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076363.1 430488 R 544404 CDS YP_003076364.1 254791527 8214976 complement(431379..432212) 1 NC_013008.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 432212 mhpR 8214976 mhpR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator MhpR YP_003076364.1 431379 R 544404 CDS YP_003076365.1 254791528 8214977 432403..434067 1 NC_013008.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 434067 mhpA 8214977 mhpA Escherichia coli O157:H7 str. TW14359 3-(3-hydroxyphenyl)propionate hydroxylase YP_003076365.1 432403 D 544404 CDS YP_003076366.1 254791529 8214978 434069..435013 1 NC_013008.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 435013 mhpB 8214978 mhpB Escherichia coli O157:H7 str. TW14359 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_003076366.1 434069 D 544404 CDS YP_003076367.1 254791530 8214979 435016..435897 1 NC_013008.1 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 435897 mhpC 8214979 mhpC Escherichia coli O157:H7 str. TW14359 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_003076367.1 435016 D 544404 CDS YP_003076368.1 254791531 8214980 435907..436716 1 NC_013008.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 436716 mhpD 8214980 mhpD Escherichia coli O157:H7 str. TW14359 2-keto-4-pentenoate hydratase YP_003076368.1 435907 D 544404 CDS YP_003076369.1 254791532 8214981 436713..437663 1 NC_013008.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 437663 mhpF 8214981 mhpF Escherichia coli O157:H7 str. TW14359 acetaldehyde dehydrogenase YP_003076369.1 436713 D 544404 CDS YP_003076370.1 254791533 8214982 437660..438673 1 NC_013008.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 438673 mhpE 8214982 mhpE Escherichia coli O157:H7 str. TW14359 4-hydroxy-2-ketovalerate aldolase YP_003076370.1 437660 D 544404 CDS YP_003076371.1 254791534 8214983 438849..440060 1 NC_013008.1 3-hydroxyphenylpropionic transporter MhpT 440060 mhpT 8214983 mhpT Escherichia coli O157:H7 str. TW14359 3-hydroxyphenylpropionic transporter MhpT YP_003076371.1 438849 D 544404 CDS YP_003076372.1 254791535 8214984 440162..440701 1 NC_013008.1 nucleoprotein/polynucleotide-associated enzyme 440701 yaiL 8214984 yaiL Escherichia coli O157:H7 str. TW14359 nucleoprotein/polynucleotide-associated enzyme YP_003076372.1 440162 D 544404 CDS YP_003076373.1 254791536 8214985 complement(440826..441659) 1 NC_013008.1 esterase 441659 frmB 8214985 frmB Escherichia coli O157:H7 str. TW14359 esterase YP_003076373.1 440826 R 544404 CDS YP_003076374.1 254791537 8214986 complement(441752..442861) 1 NC_013008.1 alcohol dehydrogenase 442861 frmA 8214986 frmA Escherichia coli O157:H7 str. TW14359 alcohol dehydrogenase YP_003076374.1 441752 R 544404 CDS YP_003076375.1 254791538 8214987 complement(442896..443171) 1 NC_013008.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 443171 frmR 8214987 frmR Escherichia coli O157:H7 str. TW14359 regulator protein FrmR YP_003076375.1 442896 R 544404 CDS YP_003076376.1 254791539 8214988 complement(443331..444377) 1 NC_013008.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 444377 fbpC 8214988 fbpC Escherichia coli O157:H7 str. TW14359 ferric transporter ATP-binding subunit YP_003076376.1 443331 R 544404 CDS YP_003076377.1 254791540 8214989 complement(444389..446467) 1 NC_013008.1 permease component of transport system for ferric iron 446467 afuB 8214989 afuB Escherichia coli O157:H7 str. TW14359 permease component of transport system for ferric iron YP_003076377.1 444389 R 544404 CDS YP_003076378.1 254791541 8214990 complement(446536..447567) 1 NC_013008.1 periplasmic ferric iron-binding protein 447567 afuA 8214990 afuA Escherichia coli O157:H7 str. TW14359 periplasmic ferric iron-binding protein YP_003076378.1 446536 R 544404 CDS YP_003076379.1 254791542 8214991 complement(447564..448868) 1 NC_013008.1 permease; hexosephosphate transport 448868 8214991 ECSP_0425 Escherichia coli O157:H7 str. TW14359 permease; hexosephosphate transport YP_003076379.1 447564 R 544404 CDS YP_003076380.1 254791543 8214992 complement(448953..450494) 1 NC_013008.1 sensor kinase; hexosephosphate transport 450494 8214992 ECSP_0426 Escherichia coli O157:H7 str. TW14359 sensor kinase; hexosephosphate transport YP_003076380.1 448953 R 544404 CDS YP_003076381.1 254791544 8214993 complement(450494..451123) 1 NC_013008.1 response regulator; hexosephosphate transport 451123 8214993 ECSP_0427 Escherichia coli O157:H7 str. TW14359 response regulator; hexosephosphate transport YP_003076381.1 450494 R 544404 CDS YP_003076382.1 254791545 8214994 451426..452388 1 NC_013008.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 452388 tauA 8214994 tauA Escherichia coli O157:H7 str. TW14359 taurine transporter substrate binding subunit YP_003076382.1 451426 D 544404 CDS YP_003076383.1 254791546 8214995 452401..453168 1 NC_013008.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 453168 tauB 8214995 tauB Escherichia coli O157:H7 str. TW14359 taurine transporter ATP-binding subunit YP_003076383.1 452401 D 544404 CDS YP_003076384.1 254791547 8214996 453165..453992 1 NC_013008.1 taurine transporter subunit 453992 tauC 8214996 tauC Escherichia coli O157:H7 str. TW14359 taurine transporter subunit YP_003076384.1 453165 D 544404 CDS YP_003076385.1 254791548 8214997 453989..454840 1 NC_013008.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 454840 tauD 8214997 tauD Escherichia coli O157:H7 str. TW14359 taurine dioxygenase YP_003076385.1 453989 D 544404 CDS YP_003076386.1 254791549 8214998 complement(454947..455921) 1 NC_013008.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 455921 hemB 8214998 hemB Escherichia coli O157:H7 str. TW14359 delta-aminolevulinic acid dehydratase YP_003076386.1 454947 R 544404 CDS YP_003076387.1 254791550 8215000 459463..460086 1 NC_013008.1 DNA-binding transcriptional regulator 460086 yaiV 8215000 yaiV Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076387.1 459463 D 544404 CDS YP_003076388.1 254791551 8215001 complement(460087..461244) 1 NC_013008.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 461244 ampH 8215001 ampH Escherichia coli O157:H7 str. TW14359 beta-lactam binding protein AmpH YP_003076388.1 460087 R 544404 CDS YP_003076389.1 254791552 8215002 complement(461336..461458) 1 NC_013008.1 hypothetical protein 461458 8215002 ECSP_0436 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076389.1 461336 R 544404 CDS YP_003076390.1 254791553 8215003 461596..462816 1 NC_013008.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 462816 sbmA 8215003 sbmA Escherichia coli O157:H7 str. TW14359 transport protein YP_003076390.1 461596 D 544404 CDS YP_003076391.1 254791554 8215004 462829..463923 1 NC_013008.1 DNA-binding transcriptional regulator 463923 yaiW 8215004 yaiW Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076391.1 462829 D 544404 CDS YP_003076392.1 254791555 8215005 complement(463982..464290) 1 NC_013008.1 inner membrane protein 464290 yaiY 8215005 yaiY Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076392.1 463982 R 544404 CDS YP_003076393.1 254791556 8215006 464550..464762 1 NC_013008.1 inner membrane protein 464762 yaiZ 8215006 yaiZ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076393.1 464550 D 544404 CDS YP_003076394.1 254791557 8215007 complement(464786..465880) 1 NC_013008.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 465880 ddl 8215007 ddl Escherichia coli O157:H7 str. TW14359 D-alanyl-alanine synthetase A YP_003076394.1 464786 R 544404 CDS YP_003076395.1 254791558 8215008 465958..466161 1 NC_013008.1 hypothetical protein 466161 8215008 ECSP_0442 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076395.1 465958 D 544404 CDS YP_003076396.1 254791559 8215009 466175..466297 1 NC_013008.1 hypothetical protein 466297 8215009 ECSP_0443 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076396.1 466175 D 544404 CDS YP_003076397.1 254791560 8215010 466343..466603 1 NC_013008.1 hypothetical protein 466603 iraP 8215010 iraP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076397.1 466343 D 544404 CDS YP_003076398.1 254791561 8215011 466704..468119 1 NC_013008.1 alkaline phosphatase 468119 phoA 8215011 phoA Escherichia coli O157:H7 str. TW14359 alkaline phosphatase YP_003076398.1 466704 D 544404 CDS YP_003076399.1 254791562 8215012 468238..468558 1 NC_013008.1 hypothetical protein 468558 psiF 8215012 psiF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076399.1 468238 D 544404 CDS YP_003076400.1 254791563 8215013 468660..469775 1 NC_013008.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 469775 adrA 8215013 adrA Escherichia coli O157:H7 str. TW14359 diguanylate cyclase AdrA YP_003076400.1 468660 D 544404 CDS YP_003076401.1 254791564 8215014 complement(469792..470601) 1 NC_013008.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 470601 proC 8215014 proC Escherichia coli O157:H7 str. TW14359 pyrroline-5-carboxylate reductase YP_003076401.1 469792 R 544404 CDS YP_003076402.1 254791565 8215015 470721..471179 1 NC_013008.1 hypothetical protein 471179 yaiI 8215015 yaiI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076402.1 470721 D 544404 CDS YP_003076403.1 254791566 8215016 471362..471886 1 NC_013008.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 471886 aroL 8215016 aroL Escherichia coli O157:H7 str. TW14359 shikimate kinase II YP_003076403.1 471362 D 544404 CDS YP_003076404.1 254791567 8215017 471936..472127 1 NC_013008.1 hypothetical protein 472127 yaiA 8215017 yaiA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076404.1 471936 D 544404 CDS YP_003076405.1 254791568 8215018 472385..473062 1 NC_013008.1 hypothetical protein 473062 aroM 8215018 aroM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076405.1 472385 D 544404 CDS YP_003076406.1 254791569 8215019 473134..473418 1 NC_013008.1 hypothetical protein 473418 yaiE 8215019 yaiE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076406.1 473134 D 544404 CDS YP_003076407.1 254791570 8215020 475560..475841 1 NC_013008.1 hypothetical protein 475841 ykiA 8215020 ykiA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076407.1 475560 D 544404 CDS YP_003076408.1 254791571 8215021 475838..476287 1 NC_013008.1 hypothetical protein 476287 8215021 ECSP_0455 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076408.1 475838 D 544404 CDS YP_003076409.1 254791572 8215022 complement(476372..477283) 1 NC_013008.1 Required for efficient pilin antigenic variation; recombination associated protein 477283 rdgC 8215022 rdgC Escherichia coli O157:H7 str. TW14359 recombination associated protein YP_003076409.1 476372 R 544404 CDS YP_003076410.1 254791573 8215023 477408..478316 1 NC_013008.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 478316 mak 8215023 mak Escherichia coli O157:H7 str. TW14359 fructokinase YP_003076410.1 477408 D 544404 CDS YP_003076411.1 254791574 8215024 complement(478459..479643) 1 NC_013008.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 479643 araJ 8215024 araJ Escherichia coli O157:H7 str. TW14359 MFS transport protein AraJ YP_003076411.1 478459 R 544404 CDS YP_003076412.1 254791575 8215025 complement(479769..482912) 1 NC_013008.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC 482912 sbcC 8215025 sbcC Escherichia coli O157:H7 str. TW14359 exonuclease SbcC YP_003076412.1 479769 R 544404 CDS YP_003076413.1 254791576 8215026 complement(482909..484111) 1 NC_013008.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD 484111 sbcD 8215026 sbcD Escherichia coli O157:H7 str. TW14359 exonuclease SbcD YP_003076413.1 482909 R 544404 CDS YP_003076414.1 254791577 8215027 484301..484990 1 NC_013008.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 484990 phoB 8215027 phoB Escherichia coli O157:H7 str. TW14359 transcriptional regulator PhoB YP_003076414.1 484301 D 544404 CDS YP_003076415.1 254791578 8215028 485048..486343 1 NC_013008.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 486343 phoR 8215028 phoR Escherichia coli O157:H7 str. TW14359 phosphate regulon sensor protein YP_003076415.1 485048 D 544404 CDS YP_003076416.1 254791579 8215029 complement(486354..486464) 1 NC_013008.1 hypothetical protein 486464 8215029 ECSP_0463 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076416.1 486354 R 544404 CDS YP_003076417.1 254791580 8215030 complement(486556..486705) 1 NC_013008.1 hypothetical protein 486705 8215030 ECSP_0464 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076417.1 486556 R 544404 CDS YP_003076418.1 254791581 8215031 486750..488069 1 NC_013008.1 branched chain amino acid transporter 488069 brnQ 8215031 brnQ Escherichia coli O157:H7 str. TW14359 branched chain amino acid transporter YP_003076418.1 486750 D 544404 CDS YP_003076419.1 254791582 8215032 488145..489518 1 NC_013008.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 489518 proY 8215032 proY Escherichia coli O157:H7 str. TW14359 proline-specific permease YP_003076419.1 488145 D 544404 CDS YP_003076420.1 254791583 8215033 489674..491491 1 NC_013008.1 maltodextrin glucosidase 491491 malZ 8215033 malZ Escherichia coli O157:H7 str. TW14359 maltodextrin glucosidase YP_003076420.1 489674 D 544404 CDS YP_003076421.1 254791584 8215034 491679..493124 1 NC_013008.1 hypothetical protein 493124 8215034 ECSP_0468 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076421.1 491679 D 544404 CDS YP_003076422.1 254791585 8215035 complement(493145..493726) 1 NC_013008.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase 493726 acpH 8215035 acpH Escherichia coli O157:H7 str. TW14359 ACP phosphodieterase YP_003076422.1 493145 R 544404 CDS YP_003076423.1 254791586 8215036 493819..494889 1 NC_013008.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 494889 queA 8215036 queA Escherichia coli O157:H7 str. TW14359 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_003076423.1 493819 D 544404 CDS YP_003076424.1 254791587 8215037 494944..496071 1 NC_013008.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 496071 tgt 8215037 tgt Escherichia coli O157:H7 str. TW14359 queuine tRNA-ribosyltransferase YP_003076424.1 494944 D 544404 CDS YP_003076425.1 254791588 8215038 496094..496426 1 NC_013008.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 496426 yajC 8215038 yajC Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit YajC YP_003076425.1 496094 D 544404 CDS YP_003076426.1 254791589 8215039 496454..498301 1 NC_013008.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 498301 secD 8215039 secD Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecD YP_003076426.1 496454 D 544404 CDS YP_003076427.1 254791590 8215040 498312..499283 1 NC_013008.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 499283 secF 8215040 secF Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecF YP_003076427.1 498312 D 544404 CDS YP_003076428.1 254791591 8215041 499435..499677 1 NC_013008.1 hypothetical protein 499677 8215041 ECSP_0475 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076428.1 499435 D 544404 CDS YP_003076429.1 254791592 8215042 499670..499951 1 NC_013008.1 hypothetical protein 499951 8215042 ECSP_0476 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076429.1 499670 D 544404 CDS YP_003076430.1 254791593 8215043 500039..500386 1 NC_013008.1 hypothetical protein 500386 yajD 8215043 yajD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076430.1 500039 D 544404 CDS YP_003076431.1 254791594 8215044 complement(500563..501447) 1 NC_013008.1 nucleoside channel phage T6/colicin K receptor 501447 tsx 8215044 tsx Escherichia coli O157:H7 str. TW14359 nucleoside channel phage T6/colicin K receptor YP_003076431.1 500563 R 544404 CDS YP_003076432.1 254791595 8215045 complement(501746..502285) 1 NC_013008.1 hypothetical protein 502285 yajI 8215045 yajI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076432.1 501746 R 544404 CDS YP_003076433.1 254791596 8215046 502436..502885 1 NC_013008.1 transcriptional regulator NrdR 502885 nrdR 8215046 nrdR Escherichia coli O157:H7 str. TW14359 transcriptional regulator NrdR YP_003076433.1 502436 D 544404 CDS YP_003076434.1 254791597 8215047 502889..503992 1 NC_013008.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 503992 ribD 8215047 ribD Escherichia coli O157:H7 str. TW14359 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_003076434.1 502889 D 544404 CDS YP_003076435.1 254791598 8215048 504081..504551 1 NC_013008.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 504551 ribH 8215048 ribH Escherichia coli O157:H7 str. TW14359 6,7-dimethyl-8-ribityllumazine synthase YP_003076435.1 504081 D 544404 CDS YP_003076436.1 254791599 8215049 504571..504990 1 NC_013008.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 504990 nusB 8215049 nusB Escherichia coli O157:H7 str. TW14359 transcription antitermination protein NusB YP_003076436.1 504571 D 544404 CDS YP_003076437.1 254791600 8215050 505068..506045 1 NC_013008.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 506045 thiL 8215050 thiL Escherichia coli O157:H7 str. TW14359 thiamine monophosphate kinase YP_003076437.1 505068 D 544404 CDS YP_003076438.1 254791601 8215051 506023..506538 1 NC_013008.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 506538 pgpA 8215051 pgpA Escherichia coli O157:H7 str. TW14359 phosphatidylglycerophosphatase A YP_003076438.1 506023 D 544404 CDS YP_003076439.1 254791602 8215052 complement(506716..508287) 1 NC_013008.1 non-LEE-encoded type III effector 508287 espY3 8215052 espY3 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076439.1 506716 R 544404 CDS YP_003076440.1 254791603 8215053 complement(508518..509492) 1 NC_013008.1 oxidoreductase 509492 yajO 8215053 yajO Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076440.1 508518 R 544404 CDS YP_003076441.1 254791604 8215054 complement(509547..511409) 1 NC_013008.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 511409 dxs 8215054 dxs Escherichia coli O157:H7 str. TW14359 1-deoxy-D-xylulose-5-phosphate synthase YP_003076441.1 509547 R 544404 CDS YP_003076442.1 254791605 8215055 complement(511434..512333) 1 NC_013008.1 geranyltranstransferase 512333 ispA 8215055 ispA Escherichia coli O157:H7 str. TW14359 geranyltranstransferase YP_003076442.1 511434 R 544404 CDS YP_003076443.1 254791606 8215056 complement(512333..512575) 1 NC_013008.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 512575 xseB 8215056 xseB Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease VII small subunit YP_003076443.1 512333 R 544404 CDS YP_003076444.1 254791607 8215057 512781..514229 1 NC_013008.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 514229 thiI 8215057 thiI Escherichia coli O157:H7 str. TW14359 thiamine biosynthesis protein ThiI YP_003076444.1 512781 D 544404 CDS YP_003076445.1 254791608 8215058 complement(514283..514873) 1 NC_013008.1 DJ-1 family protein 514873 yajL 8215058 yajL Escherichia coli O157:H7 str. TW14359 DJ-1 family protein YP_003076445.1 514283 R 544404 CDS YP_003076446.1 254791609 8215059 complement(514836..515747) 1 NC_013008.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 515747 panE 8215059 panE Escherichia coli O157:H7 str. TW14359 2-dehydropantoate 2-reductase YP_003076446.1 514836 R 544404 CDS YP_003076447.1 254791610 8215060 515915..516406 1 NC_013008.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 516406 yajQ 8215060 yajQ Escherichia coli O157:H7 str. TW14359 nucleotide-binding protein YP_003076447.1 515915 D 544404 CDS YP_003076448.1 254791611 8215061 complement(516534..517898) 1 NC_013008.1 transporter 517898 yajR 8215061 yajR Escherichia coli O157:H7 str. TW14359 transporter YP_003076448.1 516534 R 544404 CDS YP_003076449.1 254791612 8215062 complement(518047..518937) 1 NC_013008.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 518937 cyoE 8215062 cyoE Escherichia coli O157:H7 str. TW14359 protoheme IX farnesyltransferase YP_003076449.1 518047 R 544404 CDS YP_003076450.1 254791613 8215063 complement(518949..519278) 1 NC_013008.1 cytochrome o ubiquinol oxidase subunit IV 519278 cyoD 8215063 cyoD Escherichia coli O157:H7 str. TW14359 cytochrome o ubiquinol oxidase subunit IV YP_003076450.1 518949 R 544404 CDS YP_003076451.1 254791614 8215064 complement(519278..519892) 1 NC_013008.1 cytochrome o ubiquinol oxidase subunit III 519892 cyoC 8215064 cyoC Escherichia coli O157:H7 str. TW14359 cytochrome o ubiquinol oxidase subunit III YP_003076451.1 519278 R 544404 CDS YP_003076452.1 254791615 8215065 complement(519882..521873) 1 NC_013008.1 cytochrome o ubiquinol oxidase subunit I 521873 cyoB 8215065 cyoB Escherichia coli O157:H7 str. TW14359 cytochrome o ubiquinol oxidase subunit I YP_003076452.1 519882 R 544404 CDS YP_003076453.1 254791616 8215066 complement(521895..522842) 1 NC_013008.1 cytochrome o ubiquinol oxidase subunit II 522842 cyoA 8215066 cyoA Escherichia coli O157:H7 str. TW14359 cytochrome o ubiquinol oxidase subunit II YP_003076453.1 521895 R 544404 CDS YP_003076454.1 254791617 8215067 complement(523302..524777) 1 NC_013008.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 524777 ampG 8215067 ampG Escherichia coli O157:H7 str. TW14359 muropeptide transporter YP_003076454.1 523302 R 544404 CDS YP_003076455.1 254791618 8215068 complement(524821..525399) 1 NC_013008.1 hypothetical protein 525399 yajG 8215068 yajG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076455.1 524821 R 544404 CDS YP_003076456.1 254791619 8215069 525704..526021 1 NC_013008.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 526021 bolA 8215069 bolA Escherichia coli O157:H7 str. TW14359 transcriptional regulator BolA YP_003076456.1 525704 D 544404 CDS YP_003076457.1 254791620 8215070 526365..527663 1 NC_013008.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 527663 tig 8215070 tig Escherichia coli O157:H7 str. TW14359 trigger factor YP_003076457.1 526365 D 544404 CDS YP_003076458.1 254791621 8215071 527908..528531 1 NC_013008.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 528531 clpP 8215071 clpP Escherichia coli O157:H7 str. TW14359 ATP-dependent Clp protease proteolytic subunit YP_003076458.1 527908 D 544404 CDS YP_003076459.1 254791622 8215072 528657..529931 1 NC_013008.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 529931 clpX 8215072 clpX Escherichia coli O157:H7 str. TW14359 ATP-dependent protease ATP-binding subunit ClpX YP_003076459.1 528657 D 544404 CDS YP_003076460.1 254791623 8215073 530119..532473 1 NC_013008.1 DNA-binding ATP-dependent protease La 532473 lon 8215073 lon Escherichia coli O157:H7 str. TW14359 DNA-binding ATP-dependent protease La YP_003076460.1 530119 D 544404 CDS YP_003076461.1 254791624 8215074 532682..532954 1 NC_013008.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 532954 hupB 8215074 hupB Escherichia coli O157:H7 str. TW14359 transcriptional regulator HU subunit beta YP_003076461.1 532682 D 544404 CDS YP_003076462.1 254791625 8215075 533146..535017 1 NC_013008.1 peptidyl-prolyl cis-trans isomerase D 535017 ppiD 8215075 ppiD Escherichia coli O157:H7 str. TW14359 peptidyl-prolyl cis-trans isomerase D YP_003076462.1 533146 D 544404 CDS YP_003076463.1 254791626 8215076 535168..535539 1 NC_013008.1 hypothetical protein 535539 ybaV 8215076 ybaV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076463.1 535168 D 544404 CDS YP_003076464.1 254791627 8215077 535645..536043 1 NC_013008.1 hypothetical protein 536043 ybaW 8215077 ybaW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076464.1 535645 D 544404 CDS YP_003076465.1 254791628 8215078 complement(536095..536790) 1 NC_013008.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 536790 queC 8215078 queC Escherichia coli O157:H7 str. TW14359 queuosine biosynthesis protein QueC YP_003076465.1 536095 R 544404 CDS YP_003076466.1 254791629 8215079 complement(536855..538555) 1 NC_013008.1 ABC transporter periplasmic-binding protein 538555 ybaE 8215079 ybaE Escherichia coli O157:H7 str. TW14359 ABC transporter periplasmic-binding protein YP_003076466.1 536855 R 544404 CDS YP_003076467.1 254791630 8215080 538655..539473 1 NC_013008.1 thiamin pyrimidine pyrophosphate hydrolase 539473 cof 8215080 cof Escherichia coli O157:H7 str. TW14359 thiamin pyrimidine pyrophosphate hydrolase YP_003076467.1 538655 D 544404 CDS YP_003076468.1 254791631 8215081 539625..540083 1 NC_013008.1 DNA-binding transcriptional regulator 540083 ybaO 8215081 ybaO Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076468.1 539625 D 544404 CDS YP_003076469.1 254791632 8215082 540113..541885 1 NC_013008.1 multidrug transporter membrane\ATP-binding proteins 541885 mdlA 8215082 mdlA Escherichia coli O157:H7 str. TW14359 multidrug transporter membrane\ATP-binding proteins YP_003076469.1 540113 D 544404 CDS YP_003076470.1 254791633 8215083 541878..543659 1 NC_013008.1 multidrug transporter membrane\ATP-binding proteins 543659 mdlB 8215083 mdlB Escherichia coli O157:H7 str. TW14359 multidrug transporter membrane\ATP-binding proteins YP_003076470.1 541878 D 544404 CDS YP_003076471.1 254791634 8215084 543840..544178 1 NC_013008.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 544178 glnK 8215084 glnK Escherichia coli O157:H7 str. TW14359 nitrogen regulatory protein P-II 2 YP_003076471.1 543840 D 544404 CDS YP_003076472.1 254791635 8215085 544208..545494 1 NC_013008.1 ammonium transporter 545494 amtB 8215085 amtB Escherichia coli O157:H7 str. TW14359 ammonium transporter YP_003076472.1 544208 D 544404 CDS YP_003076473.1 254791636 8215086 complement(545543..546403) 1 NC_013008.1 acyl-CoA thioesterase 546403 tesB 8215086 tesB Escherichia coli O157:H7 str. TW14359 acyl-CoA thioesterase YP_003076473.1 545543 R 544404 CDS YP_003076474.1 254791637 8215087 546621..547193 1 NC_013008.1 outer membrane lipoprotein 547193 ybaY 8215087 ybaY Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003076474.1 546621 D 544404 CDS YP_003076475.1 254791638 8215088 complement(547226..547615) 1 NC_013008.1 methyltransferase 547615 ybaZ 8215088 ybaZ Escherichia coli O157:H7 str. TW14359 methyltransferase YP_003076475.1 547226 R 544404 CDS YP_003076476.1 254791639 8215089 547916..548269 1 NC_013008.1 hypothetical protein 548269 ybaA 8215089 ybaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076476.1 547916 D 544404 CDS YP_003076477.1 254791640 8215090 complement(548311..549861) 1 NC_013008.1 hypothetical protein 549861 ylaB 8215090 ylaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076477.1 548311 R 544404 CDS YP_003076478.1 254791641 8215091 complement(550025..550495) 1 NC_013008.1 inner membrane protein 550495 ylaC 8215091 ylaC Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076478.1 550025 R 544404 CDS YP_003076479.1 254791642 8215092 complement(550611..551162) 1 NC_013008.1 maltose O-acetyltransferase 551162 maa 8215092 maa Escherichia coli O157:H7 str. TW14359 maltose O-acetyltransferase YP_003076479.1 550611 R 544404 CDS YP_003076480.1 254791643 8215093 complement(551334..551552) 1 NC_013008.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 551552 hha 8215093 hha Escherichia coli O157:H7 str. TW14359 hemolysin expression-modulating protein YP_003076480.1 551334 R 544404 CDS YP_003076481.1 254791644 8215094 complement(551578..551952) 1 NC_013008.1 hypothetical protein 551952 ybaJ 8215094 ybaJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076481.1 551578 R 544404 CDS YP_003076482.1 254791645 8215095 complement(552498..555647) 1 NC_013008.1 multidrug efflux system protein 555647 acrB 8215095 acrB Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein YP_003076482.1 552498 R 544404 CDS YP_003076483.1 254791646 8215096 complement(555670..556863) 1 NC_013008.1 multidrug efflux system 556863 acrA 8215096 acrA Escherichia coli O157:H7 str. TW14359 multidrug efflux system YP_003076483.1 555670 R 544404 CDS YP_003076484.1 254791647 8215097 557005..557652 1 NC_013008.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 557652 acrR 8215097 acrR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor AcrR YP_003076484.1 557005 D 544404 CDS YP_003076485.1 254791648 8215098 557780..561142 1 NC_013008.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 561142 kefA 8215098 kefA Escherichia coli O157:H7 str. TW14359 potassium efflux protein KefA YP_003076485.1 557780 D 544404 CDS YP_003076486.1 254791649 8215099 complement(561181..561345) 1 NC_013008.1 hypothetical protein 561345 ybaM 8215099 ybaM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076486.1 561181 R 544404 CDS YP_003076487.1 254791650 8215100 complement(561359..561886) 1 NC_013008.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 561886 priC 8215100 priC Escherichia coli O157:H7 str. TW14359 primosomal replication protein N'' YP_003076487.1 561359 R 544404 CDS YP_003076488.1 254791651 8215101 561956..562333 1 NC_013008.1 hypothetical protein 562333 ybaN 8215101 ybaN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076488.1 561956 D 544404 CDS YP_003076489.1 254791652 8215102 562486..563037 1 NC_013008.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 563037 apt 8215102 apt Escherichia coli O157:H7 str. TW14359 adenine phosphoribosyltransferase YP_003076489.1 562486 D 544404 CDS YP_003076490.1 254791653 8215103 563166..565097 1 NC_013008.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 565097 dnaX 8215103 dnaX Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunits gamma and tau YP_003076490.1 563166 D 544404 CDS YP_003076491.1 254791654 8215104 565150..565479 1 NC_013008.1 hypothetical protein 565479 ybaB 8215104 ybaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076491.1 565150 D 544404 CDS YP_003076492.1 254791655 8215105 565479..566084 1 NC_013008.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 566084 recR 8215105 recR Escherichia coli O157:H7 str. TW14359 recombination protein RecR YP_003076492.1 565479 D 544404 CDS YP_003076493.1 254791656 8215106 566194..568068 1 NC_013008.1 molecular chaperone; heat shock protein 90 568068 htpG 8215106 htpG Escherichia coli O157:H7 str. TW14359 heat shock protein 90 YP_003076493.1 566194 D 544404 CDS YP_003076494.1 254791657 8215107 568249..568893 1 NC_013008.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 568893 adk 8215107 adk Escherichia coli O157:H7 str. TW14359 adenylate kinase YP_003076494.1 568249 D 544404 CDS YP_003076495.1 254791658 8215108 569025..569987 1 NC_013008.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 569987 hemH 8215108 hemH Escherichia coli O157:H7 str. TW14359 ferrochelatase YP_003076495.1 569025 D 544404 CDS YP_003076496.1 254791659 8215109 complement(569984..570943) 1 NC_013008.1 acetyl esterase 570943 aes 8215109 aes Escherichia coli O157:H7 str. TW14359 acetyl esterase YP_003076496.1 569984 R 544404 CDS YP_003076497.1 254791660 8215110 571095..572399 1 NC_013008.1 inosine/guanosine kinase 572399 gsk 8215110 gsk Escherichia coli O157:H7 str. TW14359 inosine/guanosine kinase YP_003076497.1 571095 D 544404 CDS YP_003076498.1 254791661 8215111 complement(572532..574208) 1 NC_013008.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 574208 ybaL 8215111 ybaL Escherichia coli O157:H7 str. TW14359 cation:proton antiport protein YP_003076498.1 572532 R 544404 CDS YP_003076499.1 254791662 8215112 complement(574445..575665) 1 NC_013008.1 fosmidomycin efflux system 575665 fsr 8215112 fsr Escherichia coli O157:H7 str. TW14359 fosmidomycin efflux system YP_003076499.1 574445 R 544404 CDS YP_003076500.1 254791663 8215113 575883..577535 1 NC_013008.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 577535 ushA 8215113 ushA Escherichia coli O157:H7 str. TW14359 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_003076500.1 575883 D 544404 CDS YP_003076501.1 254791664 8215114 complement(577572..578051) 1 NC_013008.1 hypothetical protein 578051 ybaK 8215114 ybaK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076501.1 577572 R 544404 CDS YP_003076502.1 254791665 8215115 complement(578255..579049) 1 NC_013008.1 hypothetical protein 579049 ybaP 8215115 ybaP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076502.1 578255 R 544404 CDS YP_003076503.1 254791666 8215116 579187..579528 1 NC_013008.1 DNA-binding transcriptional regulator 579528 ybaQ 8215116 ybaQ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076503.1 579187 D 544404 CDS YP_003076504.1 254791667 8215117 complement(579743..582247) 1 NC_013008.1 copper exporting ATPase 582247 copA 8215117 copA Escherichia coli O157:H7 str. TW14359 copper exporting ATPase YP_003076504.1 579743 R 544404 CDS YP_003076505.1 254791668 8215118 582509..583441 1 NC_013008.1 catalyzes the formation of glutamate from glutamine; glutaminase 583441 ybaS 8215118 ybaS Escherichia coli O157:H7 str. TW14359 glutaminase YP_003076505.1 582509 D 544404 CDS YP_003076506.1 254791669 8215119 583444..584736 1 NC_013008.1 transporter 584736 ybaT 8215119 ybaT Escherichia coli O157:H7 str. TW14359 transporter YP_003076506.1 583444 D 544404 CDS YP_003076507.1 254791670 8215120 585074..586429 1 NC_013008.1 outer membrane export protein 586429 8215120 ECSP_0554 Escherichia coli O157:H7 str. TW14359 outer membrane export protein YP_003076507.1 585074 D 544404 CDS YP_003076508.1 254791671 8215121 586532..590917 1 NC_013008.1 hypothetical protein 590917 8215121 ECSP_0555 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076508.1 586532 D 544404 CDS YP_003076509.1 254791672 8215122 591125..604264 1 NC_013008.1 RTX family exoprotein 604264 8215122 ECSP_0556 Escherichia coli O157:H7 str. TW14359 RTX family exoprotein YP_003076509.1 591125 D 544404 CDS YP_003076510.1 254791673 8215124 606685..608847 1 NC_013008.1 cytoplasmic membrane export protein 608847 8215124 ECSP_0558 Escherichia coli O157:H7 str. TW14359 cytoplasmic membrane export protein YP_003076510.1 606685 D 544404 CDS YP_003076511.1 254791674 8215125 608844..610019 1 NC_013008.1 membrane spanning export protein 610019 8215125 ECSP_0559 Escherichia coli O157:H7 str. TW14359 membrane spanning export protein YP_003076511.1 608844 D 544404 CDS YP_003076512.1 254791675 8215126 610016..610423 1 NC_013008.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 610423 cueR 8215126 cueR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator CueR YP_003076512.1 610016 D 544404 CDS YP_003076513.1 254791676 8215127 complement(610627..611049) 1 NC_013008.1 hypothetical protein 611049 8215127 ECSP_0561 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076513.1 610627 R 544404 CDS YP_003076514.1 254791677 8215128 complement(611134..612150) 1 NC_013008.1 hypothetical protein 612150 8215128 ECSP_0562 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076514.1 611134 R 544404 CDS YP_003076515.1 254791678 8215129 complement(612248..612370) 1 NC_013008.1 hypothetical protein 612370 8215129 ECSP_0563 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076515.1 612248 R 544404 CDS YP_003076516.1 254791679 8215130 612517..612879 1 NC_013008.1 hypothetical protein 612879 8215130 ECSP_0564 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076516.1 612517 D 544404 CDS YP_003076517.1 254791680 8215131 complement(613058..613516) 1 NC_013008.1 hypothetical protein 613516 ybbJ 8215131 ybbJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076517.1 613058 R 544404 CDS YP_003076518.1 254791681 8215132 complement(613513..614430) 1 NC_013008.1 protease, membrane anchored 614430 ybbK 8215132 ybbK Escherichia coli O157:H7 str. TW14359 protease, membrane anchored YP_003076518.1 613513 R 544404 CDS YP_003076519.1 254791682 8215133 614576..615253 1 NC_013008.1 ABC transporter ATP-binding protein YbbL 615253 ybbL 8215133 ybbL Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YbbL YP_003076519.1 614576 D 544404 CDS YP_003076520.1 254791683 8215134 615240..616019 1 NC_013008.1 inner membrane protein 616019 ybbM 8215134 ybbM Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076520.1 615240 D 544404 CDS YP_003076521.1 254791684 8215135 complement(616082..616936) 1 NC_013008.1 thioredoxin domain-containing protein 616936 ybbN 8215135 ybbN Escherichia coli O157:H7 str. TW14359 thioredoxin domain-containing protein YP_003076521.1 616082 R 544404 CDS YP_003076522.1 254791685 8215136 complement(616997..617806) 1 NC_013008.1 short chain dehydrogenase 617806 ybbO 8215136 ybbO Escherichia coli O157:H7 str. TW14359 short chain dehydrogenase YP_003076522.1 616997 R 544404 CDS YP_003076523.1 254791686 8215137 complement(617796..618422) 1 NC_013008.1 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 618422 tesA 8215137 tesA Escherichia coli O157:H7 str. TW14359 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_003076523.1 617796 R 544404 CDS YP_003076524.1 254791687 8215138 618390..619076 1 NC_013008.1 ABC transporter ATP-binding protein YbbA 619076 ybbA 8215138 ybbA Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YbbA YP_003076524.1 618390 D 544404 CDS YP_003076525.1 254791688 8215139 619073..621487 1 NC_013008.1 inner membrane protein 621487 ybbP 8215139 ybbP Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076525.1 619073 D 544404 CDS YP_003076526.1 254791689 8215140 621917..626113 1 NC_013008.1 hypothetical protein 626113 8215140 ECSP_0574 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076526.1 621917 D 544404 CDS YP_003076527.1 254791690 8215141 626094..626354 1 NC_013008.1 hypothetical protein 626354 ybbD 8215141 ybbD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076527.1 626094 D 544404 CDS YP_003076528.1 254791691 8215142 complement(626537..626689) 1 NC_013008.1 hypothetical protein 626689 8215142 ECSP_0576 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076528.1 626537 R 544404 CDS YP_003076529.1 254791692 8215143 complement(627098..627505) 1 NC_013008.1 DNA-binding transcriptional regulator 627505 ylbG 8215143 ylbG Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076529.1 627098 R 544404 CDS YP_003076530.1 254791693 8215144 complement(627585..628679) 1 NC_013008.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 628679 ybbB 8215144 ybbB Escherichia coli O157:H7 str. TW14359 tRNA 2-selenouridine synthase YP_003076530.1 627585 R 544404 CDS YP_003076531.1 254791694 8215145 complement(628748..629674) 1 NC_013008.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 629674 ybbS 8215145 ybbS Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator AllS YP_003076531.1 628748 R 544404 CDS YP_003076532.1 254791695 8215146 629904..630386 1 NC_013008.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 630386 allA 8215146 allA Escherichia coli O157:H7 str. TW14359 ureidoglycolate hydrolase YP_003076532.1 629904 D 544404 CDS YP_003076533.1 254791696 8215147 630464..631279 1 NC_013008.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 631279 allR 8215147 allR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor AllR YP_003076533.1 630464 D 544404 CDS YP_003076534.1 254791697 8215148 631369..633150 1 NC_013008.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 633150 gcl 8215148 gcl Escherichia coli O157:H7 str. TW14359 glyoxylate carboligase YP_003076534.1 631369 D 544404 CDS YP_003076535.1 254791698 8215149 633163..633939 1 NC_013008.1 hydroxypyruvate isomerase 633939 hyi 8215149 hyi Escherichia coli O157:H7 str. TW14359 hydroxypyruvate isomerase YP_003076535.1 633163 D 544404 CDS YP_003076536.1 254791699 8215150 634040..634918 1 NC_013008.1 tartronate semialdehyde reductase, NADH-dependent 634918 glxR 8215150 glxR Escherichia coli O157:H7 str. TW14359 tartronate semialdehyde reductase, NADH-dependent YP_003076536.1 634040 D 544404 CDS YP_003076537.1 254791700 8215151 635087..636478 1 NC_013008.1 allantoin permease 636478 ybbW 8215151 ybbW Escherichia coli O157:H7 str. TW14359 allantoin permease YP_003076537.1 635087 D 544404 CDS YP_003076538.1 254791701 8215153 637933..639234 1 NC_013008.1 purine permease YbbY 639234 ybbY 8215153 ybbY Escherichia coli O157:H7 str. TW14359 purine permease YbbY YP_003076538.1 637933 D 544404 CDS YP_003076539.1 254791702 8215154 639256..640401 1 NC_013008.1 glycerate kinase II 640401 glxK 8215154 glxK Escherichia coli O157:H7 str. TW14359 glycerate kinase II YP_003076539.1 639256 D 544404 CDS YP_003076540.1 254791703 8215155 complement(640629..641414) 1 NC_013008.1 hypothetical protein 641414 ylbA 8215155 ylbA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076540.1 640629 R 544404 CDS YP_003076541.1 254791704 8215156 complement(641425..642660) 1 NC_013008.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 642660 allC 8215156 allC Escherichia coli O157:H7 str. TW14359 allantoate amidohydrolase YP_003076541.1 641425 R 544404 CDS YP_003076542.1 254791705 8215157 complement(642682..643731) 1 NC_013008.1 ureidoglycolate dehydrogenase 643731 allD 8215157 allD Escherichia coli O157:H7 str. TW14359 ureidoglycolate dehydrogenase YP_003076542.1 642682 R 544404 CDS YP_003076543.1 254791706 8215158 644048..645715 1 NC_013008.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 645715 fdrA 8215158 fdrA Escherichia coli O157:H7 str. TW14359 membrane protein FdrA YP_003076543.1 644048 D 544404 CDS YP_003076544.1 254791707 8215159 645725..646984 1 NC_013008.1 hypothetical protein 646984 ylbE 8215159 ylbE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076544.1 645725 D 544404 CDS YP_003076545.1 254791708 8215160 646995..647810 1 NC_013008.1 hypothetical protein 647810 ylbF 8215160 ylbF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076545.1 646995 D 544404 CDS YP_003076546.1 254791709 8215161 647807..648700 1 NC_013008.1 carbamate kinase 648700 ybcF 8215161 ybcF Escherichia coli O157:H7 str. TW14359 carbamate kinase YP_003076546.1 647807 D 544404 CDS YP_003076547.1 254791710 8215162 complement(648839..649906) 1 NC_013008.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 649906 purK 8215162 purK Escherichia coli O157:H7 str. TW14359 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_003076547.1 648839 R 544404 CDS YP_003076548.1 254791711 8215163 complement(649903..650412) 1 NC_013008.1 N5-carboxyaminoimidazole ribonucleotide mutase 650412 purE 8215163 purE Escherichia coli O157:H7 str. TW14359 N5-carboxyaminoimidazole ribonucleotide mutase YP_003076548.1 649903 R 544404 CDS YP_003076549.1 254791712 8215164 complement(650530..651252) 1 NC_013008.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 651252 lpxH 8215164 lpxH Escherichia coli O157:H7 str. TW14359 UDP-2,3-diacylglucosamine hydrolase YP_003076549.1 650530 R 544404 CDS YP_003076550.1 254791713 8215165 complement(651255..651749) 1 NC_013008.1 peptidyl-prolyl cis-trans isomerase B 651749 ppiB 8215165 ppiB Escherichia coli O157:H7 str. TW14359 peptidyl-prolyl cis-trans isomerase B YP_003076550.1 651255 R 544404 CDS YP_003076551.1 254791714 8215166 651923..653308 1 NC_013008.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 653308 cysS 8215166 cysS Escherichia coli O157:H7 str. TW14359 cysteinyl-tRNA synthetase YP_003076551.1 651923 D 544404 CDS YP_003076552.1 254791715 8215167 complement(653344..653865) 1 NC_013008.1 hypothetical protein 653865 ybcI 8215167 ybcI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076552.1 653344 R 544404 CDS YP_003076553.1 254791716 8215168 complement(653973..654185) 1 NC_013008.1 hypothetical protein 654185 ybcJ 8215168 ybcJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076553.1 653973 R 544404 CDS YP_003076554.1 254791717 8215169 complement(654187..655053) 1 NC_013008.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 655053 folD 8215169 folD Escherichia coli O157:H7 str. TW14359 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_003076554.1 654187 R 544404 CDS YP_003076555.1 254791718 8215170 655533..656075 1 NC_013008.1 fimbrial-like adhesin protein 656075 sfmA 8215170 sfmA Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076555.1 655533 D 544404 CDS YP_003076556.1 254791719 8215171 656295..656987 1 NC_013008.1 pilin chaperone, periplasmic 656987 sfmC 8215171 sfmC Escherichia coli O157:H7 str. TW14359 pilin chaperone, periplasmic YP_003076556.1 656295 D 544404 CDS YP_003076557.1 254791720 8215172 657018..659627 1 NC_013008.1 outer membrane export usher protein 659627 sfmD 8215172 sfmD Escherichia coli O157:H7 str. TW14359 outer membrane export usher protein YP_003076557.1 657018 D 544404 CDS YP_003076558.1 254791721 8215173 659640..660647 1 NC_013008.1 fimbrial-like adhesin protein 660647 sfmH 8215173 sfmH Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076558.1 659640 D 544404 CDS YP_003076559.1 254791722 8215174 660658..661173 1 NC_013008.1 fimbrial protein 661173 sfmF 8215174 sfmF Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003076559.1 660658 D 544404 CDS YP_003076560.1 254791723 8215175 complement(661176..661808) 1 NC_013008.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 661808 fimZ 8215175 fimZ Escherichia coli O157:H7 str. TW14359 transcriptional regulator FimZ YP_003076560.1 661176 R 544404 CDS YP_003076561.1 254791724 8215177 complement(662173..662934) 1 NC_013008.1 DNA-binding transcriptional activator of porin biosynthesis 662934 envY 8215177 envY Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator of porin biosynthesis YP_003076561.1 662173 R 544404 CDS YP_003076562.1 254791725 8215178 complement(663117..664007) 1 NC_013008.1 hypothetical protein 664007 ybcH 8215178 ybcH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076562.1 663117 R 544404 CDS YP_003076563.1 254791726 8215179 complement(664008..666980) 1 NC_013008.1 bacteriophage N4 receptor, outer membrane subunit 666980 nfrA 8215179 nfrA Escherichia coli O157:H7 str. TW14359 bacteriophage N4 receptor, outer membrane subunit YP_003076563.1 664008 R 544404 CDS YP_003076564.1 254791727 8215180 complement(666967..669204) 1 NC_013008.1 bacteriophage N4 adsorption protein B 669204 nfrB 8215180 nfrB Escherichia coli O157:H7 str. TW14359 bacteriophage N4 adsorption protein B YP_003076564.1 666967 R 544404 CDS YP_003076565.1 254791728 8215181 complement(669470..670606) 1 NC_013008.1 transposase 670606 8215181 ECSP_0615 Escherichia coli O157:H7 str. TW14359 transposase YP_003076565.1 669470 R 544404 CDS YP_003076566.1 254791729 8215182 complement(670821..671042) 1 NC_013008.1 hypothetical protein 671042 8215182 ECSP_0616 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076566.1 670821 R 544404 CDS YP_003076567.1 254791730 8215183 complement(671069..672403) 1 NC_013008.1 hypothetical protein 672403 8215183 ECSP_0617 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076567.1 671069 R 544404 CDS YP_003076568.1 254791731 8215184 complement(672572..672832) 1 NC_013008.1 hypothetical protein 672832 8215184 ECSP_0618 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076568.1 672572 R 544404 CDS YP_003076569.1 254791732 8215185 complement(672996..677846) 1 NC_013008.1 hypothetical protein 677846 8215185 ECSP_0619 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076569.1 672996 R 544404 CDS YP_003076570.1 254791733 8215186 complement(677866..678327) 1 NC_013008.1 hypothetical protein 678327 8215186 ECSP_0620 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076570.1 677866 R 544404 CDS YP_003076571.1 254791734 8215187 complement(678355..680256) 1 NC_013008.1 hypothetical protein 680256 8215187 ECSP_0621 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076571.1 678355 R 544404 CDS YP_003076572.1 254791735 8215188 complement(680850..682298) 1 NC_013008.1 sensor kinase CusS 682298 cusS 8215188 cusS Escherichia coli O157:H7 str. TW14359 sensor kinase CusS YP_003076572.1 680850 R 544404 CDS YP_003076573.1 254791736 8215189 complement(682288..682971) 1 NC_013008.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 682971 cusR 8215189 cusR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator CusR YP_003076573.1 682288 R 544404 CDS YP_003076574.1 254791737 8215190 683128..684510 1 NC_013008.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 684510 cusC 8215190 cusC Escherichia coli O157:H7 str. TW14359 copper/silver efflux system outer membrane protein CusC YP_003076574.1 683128 D 544404 CDS YP_003076575.1 254791738 8215191 684534..684866 1 NC_013008.1 periplasmic copper-binding protein 684866 cusF 8215191 cusF Escherichia coli O157:H7 str. TW14359 periplasmic copper-binding protein YP_003076575.1 684534 D 544404 CDS YP_003076576.1 254791739 8215192 684882..686105 1 NC_013008.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 686105 cusB 8215192 cusB Escherichia coli O157:H7 str. TW14359 copper/silver efflux system membrane fusion protein CusB YP_003076576.1 684882 D 544404 CDS YP_003076577.1 254791740 8215193 686117..689254 1 NC_013008.1 copper/silver efflux system, membrane component 689254 cusA 8215193 cusA Escherichia coli O157:H7 str. TW14359 copper/silver efflux system, membrane component YP_003076577.1 686117 D 544404 CDS YP_003076578.1 254791741 8215194 689356..690732 1 NC_013008.1 phenylalanine transporter 690732 pheP 8215194 pheP Escherichia coli O157:H7 str. TW14359 phenylalanine transporter YP_003076578.1 689356 D 544404 CDS YP_003076579.1 254791742 8215195 complement(690800..692047) 1 NC_013008.1 mechanosensitive channel 692047 ybdG 8215195 ybdG Escherichia coli O157:H7 str. TW14359 mechanosensitive channel YP_003076579.1 690800 R 544404 CDS YP_003076580.1 254791743 8215196 complement(692155..692808) 1 NC_013008.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 692808 nfnB 8215196 nfnB Escherichia coli O157:H7 str. TW14359 dihydropteridine reductase YP_003076580.1 692155 R 544404 CDS YP_003076581.1 254791744 8215197 complement(692902..693270) 1 NC_013008.1 hypothetical protein 693270 ybdF 8215197 ybdF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076581.1 692902 R 544404 CDS YP_003076582.1 254791745 8215198 complement(693335..693583) 1 NC_013008.1 inner membrane protein 693583 ybdJ 8215198 ybdJ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076582.1 693335 R 544404 CDS YP_003076583.1 254791746 8215199 complement(693649..694767) 1 NC_013008.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 694767 ybdK 8215199 ybdK Escherichia coli O157:H7 str. TW14359 carboxylate-amine ligase YP_003076583.1 693649 R 544404 CDS YP_003076584.1 254791747 8215200 695062..695358 1 NC_013008.1 hypothetical protein 695358 8215200 ECSP_0634 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076584.1 695062 D 544404 CDS YP_003076585.1 254791748 8215201 695709..695861 1 NC_013008.1 toxic polypeptide, small 695861 hokE 8215201 hokE Escherichia coli O157:H7 str. TW14359 toxic polypeptide, small YP_003076585.1 695709 D 544404 CDS YP_003076586.1 254791749 8215202 complement(695983..696612) 1 NC_013008.1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 696612 entD 8215202 entD Escherichia coli O157:H7 str. TW14359 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_003076586.1 695983 R 544404 CDS YP_003076587.1 254791750 8215203 complement(696778..699018) 1 NC_013008.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 699018 fepA 8215203 fepA Escherichia coli O157:H7 str. TW14359 outer membrane receptor FepA YP_003076587.1 696778 R 544404 CDS YP_003076588.1 254791751 8215204 699339..700463 1 NC_013008.1 enterobactin/ferric enterobactin esterase 700463 fes 8215204 fes Escherichia coli O157:H7 str. TW14359 enterobactin/ferric enterobactin esterase YP_003076588.1 699339 D 544404 CDS YP_003076589.1 254791752 8215205 700466..700684 1 NC_013008.1 hypothetical protein 700684 ybdZ 8215205 ybdZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076589.1 700466 D 544404 CDS YP_003076590.1 254791753 8215206 700681..704562 1 NC_013008.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 704562 entF 8215206 entF Escherichia coli O157:H7 str. TW14359 enterobactin synthase subunit F YP_003076590.1 700681 D 544404 CDS YP_003076591.1 254791754 8215207 704778..705911 1 NC_013008.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 705911 fepE 8215207 fepE Escherichia coli O157:H7 str. TW14359 ferric enterobactin transport protein FepE YP_003076591.1 704778 D 544404 CDS YP_003076592.1 254791755 8215208 complement(705908..706723) 1 NC_013008.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 706723 fepC 8215208 fepC Escherichia coli O157:H7 str. TW14359 iron-enterobactin transporter ATP-binding protein YP_003076592.1 705908 R 544404 CDS YP_003076593.1 254791756 8215209 complement(706720..707712) 1 NC_013008.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 707712 fepG 8215209 fepG Escherichia coli O157:H7 str. TW14359 iron-enterobactin transporter permease YP_003076593.1 706720 R 544404 CDS YP_003076594.1 254791757 8215210 complement(707709..708713) 1 NC_013008.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 708713 fepD 8215210 fepD Escherichia coli O157:H7 str. TW14359 iron-enterobactin transporter membrane protein YP_003076594.1 707709 R 544404 CDS YP_003076595.1 254791758 8215211 708824..710074 1 NC_013008.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 710074 ybdA 8215211 ybdA Escherichia coli O157:H7 str. TW14359 enterobactin exporter EntS YP_003076595.1 708824 D 544404 CDS YP_003076596.1 254791759 8215212 complement(710078..711034) 1 NC_013008.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 711034 fepB 8215212 fepB Escherichia coli O157:H7 str. TW14359 iron-enterobactin transporter periplasmic binding protein YP_003076596.1 710078 R 544404 CDS YP_003076597.1 254791760 8215213 711223..712398 1 NC_013008.1 isochorismate synthase 1 712398 entC 8215213 entC Escherichia coli O157:H7 str. TW14359 isochorismate synthase 1 YP_003076597.1 711223 D 544404 CDS YP_003076598.1 254791761 8215214 712408..714018 1 NC_013008.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 714018 entE 8215214 entE Escherichia coli O157:H7 str. TW14359 enterobactin synthase subunit E YP_003076598.1 712408 D 544404 CDS YP_003076599.1 254791762 8215215 714032..714889 1 NC_013008.1 2,3-dihydro-2,3-dihydroxybenzoate synthetase 714889 entB 8215215 entB Escherichia coli O157:H7 str. TW14359 2,3-dihydro-2,3-dihydroxybenzoate synthetase YP_003076599.1 714032 D 544404 CDS YP_003076600.1 254791763 8215216 714889..715635 1 NC_013008.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 715635 entA 8215216 entA Escherichia coli O157:H7 str. TW14359 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_003076600.1 714889 D 544404 CDS YP_003076601.1 254791764 8215217 715638..716051 1 NC_013008.1 hypothetical protein 716051 ybdB 8215217 ybdB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076601.1 715638 D 544404 CDS YP_003076602.1 254791765 8215218 716232..718337 1 NC_013008.1 carbon starvation protein 718337 cstA 8215218 cstA Escherichia coli O157:H7 str. TW14359 carbon starvation protein YP_003076602.1 716232 D 544404 CDS YP_003076603.1 254791766 8215219 718519..718716 1 NC_013008.1 hypothetical protein 718716 ybdD 8215219 ybdD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076603.1 718519 D 544404 CDS YP_003076604.1 254791767 8215220 complement(718726..719814) 1 NC_013008.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 719814 ybdH 8215220 ybdH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076604.1 718726 R 544404 CDS YP_003076605.1 254791768 8215221 719923..721083 1 NC_013008.1 catalyzes the transfer of an amino moiety; aminotransferase 721083 ybdL 8215221 ybdL Escherichia coli O157:H7 str. TW14359 aminotransferase YP_003076605.1 719923 D 544404 CDS YP_003076606.1 254791769 8215222 complement(721084..721713) 1 NC_013008.1 hypothetical protein 721713 ybdM 8215222 ybdM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076606.1 721084 R 544404 CDS YP_003076607.1 254791770 8215223 complement(721686..722906) 1 NC_013008.1 hypothetical protein 722906 ybdN 8215223 ybdN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076607.1 721686 R 544404 CDS YP_003076608.1 254791771 8215224 complement(723053..723955) 1 NC_013008.1 DNA-binding transcriptional regulator 723955 ybdO 8215224 ybdO Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076608.1 723053 R 544404 CDS YP_003076609.1 254791772 8215225 complement(724165..724911) 1 NC_013008.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 724911 dsbG 8215225 dsbG Escherichia coli O157:H7 str. TW14359 disulfide isomerase/thiol-disulfide oxidase YP_003076609.1 724165 R 544404 CDS YP_003076610.1 254791773 8215226 725283..725846 1 NC_013008.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 725846 ahpC 8215226 ahpC Escherichia coli O157:H7 str. TW14359 alkyl hydroperoxide reductase YP_003076610.1 725283 D 544404 CDS YP_003076611.1 254791774 8215227 725975..727540 1 NC_013008.1 alkyl hydroperoxide reductase 727540 ahpF 8215227 ahpF Escherichia coli O157:H7 str. TW14359 alkyl hydroperoxide reductase YP_003076611.1 725975 D 544404 CDS YP_003076612.1 254791775 8215228 complement(727661..728089) 1 NC_013008.1 universal stress protein UP12 728089 uspG 8215228 uspG Escherichia coli O157:H7 str. TW14359 universal stress protein UP12 YP_003076612.1 727661 R 544404 CDS YP_003076613.1 254791776 8215229 728310..729548 1 NC_013008.1 oxidoreductase 729548 ybdR 8215229 ybdR Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076613.1 728310 D 544404 CDS YP_003076614.1 254791777 8215230 complement(729779..730189) 1 NC_013008.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 730189 rnk 8215230 rnk Escherichia coli O157:H7 str. TW14359 nucleoside diphosphate kinase regulator YP_003076614.1 729779 R 544404 CDS YP_003076615.1 254791778 8215231 complement(730419..731225) 1 NC_013008.1 ribonuclease I 731225 rna 8215231 rna Escherichia coli O157:H7 str. TW14359 ribonuclease I YP_003076615.1 730419 R 544404 CDS YP_003076616.1 254791779 8215232 complement(731339..732802) 1 NC_013008.1 citrate:succinate antiporter 732802 citT 8215232 citT Escherichia coli O157:H7 str. TW14359 citrate:succinate antiporter YP_003076616.1 731339 R 544404 CDS YP_003076617.1 254791780 8215233 complement(732853..733731) 1 NC_013008.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 733731 citG 8215233 citG Escherichia coli O157:H7 str. TW14359 triphosphoribosyl-dephospho-CoA synthase YP_003076617.1 732853 R 544404 CDS YP_003076618.1 254791781 8215234 complement(733706..734257) 1 NC_013008.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase 734257 citX 8215234 citX Escherichia coli O157:H7 str. TW14359 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase YP_003076618.1 733706 R 544404 CDS YP_003076619.1 254791782 8215235 complement(734261..735793) 1 NC_013008.1 citrate lyase, citrate-ACP transferase subunit alpha 735793 citF 8215235 citF Escherichia coli O157:H7 str. TW14359 citrate lyase, citrate-ACP transferase subunit alpha YP_003076619.1 734261 R 544404 CDS YP_003076620.1 254791783 8215236 complement(735804..736712) 1 NC_013008.1 citrate lyase, citryl-ACP lyase subunit beta 736712 citE 8215236 citE Escherichia coli O157:H7 str. TW14359 citrate lyase, citryl-ACP lyase subunit beta YP_003076620.1 735804 R 544404 CDS YP_003076621.1 254791784 8215237 complement(736709..737005) 1 NC_013008.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 737005 citD 8215237 citD Escherichia coli O157:H7 str. TW14359 citrate lyase subunit gamma YP_003076621.1 736709 R 544404 CDS YP_003076622.1 254791785 8215238 complement(737020..738078) 1 NC_013008.1 citrate lyase synthetase 738078 citC 8215238 citC Escherichia coli O157:H7 str. TW14359 citrate lyase synthetase YP_003076622.1 737020 R 544404 CDS YP_003076623.1 254791786 8215239 738458..740116 1 NC_013008.1 sensory histidine kinase in two-component regulatory system with citB 740116 citA 8215239 citA Escherichia coli O157:H7 str. TW14359 sensory histidine kinase in two-component regulatory system with citB YP_003076623.1 738458 D 544404 CDS YP_003076624.1 254791787 8215240 740085..740765 1 NC_013008.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 740765 dpiA 8215240 dpiA Escherichia coli O157:H7 str. TW14359 two-component response regulator DpiA YP_003076624.1 740085 D 544404 CDS YP_003076625.1 254791788 8215241 complement(740806..742191) 1 NC_013008.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 742191 dcuC 8215241 dcuC Escherichia coli O157:H7 str. TW14359 C4-dicarboxylate transporter DcuC YP_003076625.1 740806 R 544404 CDS YP_003076626.1 254791789 8215242 742780..743340 1 NC_013008.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 743340 pagP 8215242 pagP Escherichia coli O157:H7 str. TW14359 palmitoyl transferase YP_003076626.1 742780 D 544404 CDS YP_003076627.1 254791790 8215243 743515..743724 1 NC_013008.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 743724 cspE 8215243 cspE Escherichia coli O157:H7 str. TW14359 cold shock protein CspE YP_003076627.1 743515 D 544404 CDS YP_003076628.1 254791791 8215244 complement(743778..744161) 1 NC_013008.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 744161 crcB 8215244 crcB Escherichia coli O157:H7 str. TW14359 camphor resistance protein CrcB YP_003076628.1 743778 R 544404 CDS YP_003076629.1 254791792 8215245 744254..745042 1 NC_013008.1 carbon-nitrogen hydrolase 745042 ybeM 8215245 ybeM Escherichia coli O157:H7 str. TW14359 carbon-nitrogen hydrolase YP_003076629.1 744254 D 544404 CDS YP_003076630.1 254791793 8215246 745171..745374 1 NC_013008.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 745374 tatE 8215246 tatE Escherichia coli O157:H7 str. TW14359 twin arginine translocase protein E YP_003076630.1 745171 D 544404 CDS YP_003076631.1 254791794 8215247 complement(745475..746440) 1 NC_013008.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 746440 lipA 8215247 lipA Escherichia coli O157:H7 str. TW14359 lipoyl synthase YP_003076631.1 745475 R 544404 CDS YP_003076632.1 254791795 8215248 complement(746649..747602) 1 NC_013008.1 DNA-binding transcriptional regulator 747602 ybeF 8215248 ybeF Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076632.1 746649 R 544404 CDS YP_003076633.1 254791796 8215249 complement(747862..748503) 1 NC_013008.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 748503 lipB 8215249 lipB Escherichia coli O157:H7 str. TW14359 lipoate-protein ligase B YP_003076633.1 747862 R 544404 CDS YP_003076634.1 254791797 8215250 complement(748604..748867) 1 NC_013008.1 hypothetical protein 748867 ybeD 8215250 ybeD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076634.1 748604 R 544404 CDS YP_003076635.1 254791798 8215251 complement(748977..750188) 1 NC_013008.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A 750188 dacA 8215251 dacA Escherichia coli O157:H7 str. TW14359 D-alanyl-D-alanine carboxypeptidase fraction A YP_003076635.1 748977 R 544404 CDS YP_003076636.1 254791799 8215252 complement(750328..751416) 1 NC_013008.1 rare lipoprotein A 751416 rlpA 8215252 rlpA Escherichia coli O157:H7 str. TW14359 rare lipoprotein A YP_003076636.1 750328 R 544404 CDS YP_003076637.1 254791800 8215253 complement(751427..752539) 1 NC_013008.1 cell wall shape-determining protein 752539 mrdB 8215253 mrdB Escherichia coli O157:H7 str. TW14359 cell wall shape-determining protein YP_003076637.1 751427 R 544404 CDS YP_003076638.1 254791801 8215254 complement(752542..754443) 1 NC_013008.1 penicillin-binding protein 2 754443 mrdA 8215254 mrdA Escherichia coli O157:H7 str. TW14359 penicillin-binding protein 2 YP_003076638.1 752542 R 544404 CDS YP_003076639.1 254791802 8215255 complement(754474..754941) 1 NC_013008.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 754941 ybeA 8215255 ybeA Escherichia coli O157:H7 str. TW14359 rRNA large subunit methyltransferase YP_003076639.1 754474 R 544404 CDS YP_003076640.1 254791803 8215256 complement(754945..755262) 1 NC_013008.1 hypothetical protein 755262 ybeB 8215256 ybeB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076640.1 754945 R 544404 CDS YP_003076641.1 254791804 8215257 complement(755522..756133) 1 NC_013008.1 alpha-ribazole-5'-P phosphatase 756133 cobC 8215257 cobC Escherichia coli O157:H7 str. TW14359 alpha-ribazole-5'-P phosphatase YP_003076641.1 755522 R 544404 CDS YP_003076642.1 254791805 8215258 complement(756157..756798) 1 NC_013008.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 756798 nadD 8215258 nadD Escherichia coli O157:H7 str. TW14359 nicotinic acid mononucleotide adenylyltransferase YP_003076642.1 756157 R 544404 CDS YP_003076643.1 254791806 8215259 complement(756800..757831) 1 NC_013008.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 757831 holA 8215259 holA Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit delta YP_003076643.1 756800 R 544404 CDS YP_003076644.1 254791807 8215260 complement(757831..758412) 1 NC_013008.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 758412 rlpB 8215260 rlpB Escherichia coli O157:H7 str. TW14359 LPS-assembly lipoprotein RlpB YP_003076644.1 757831 R 544404 CDS YP_003076645.1 254791808 8215261 complement(758427..761009) 1 NC_013008.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 761009 leuS 8215261 leuS Escherichia coli O157:H7 str. TW14359 leucyl-tRNA synthetase YP_003076645.1 758427 R 544404 CDS YP_003076646.1 254791809 8215262 761245..761727 1 NC_013008.1 hypothetical protein 761727 ybeL 8215262 ybeL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076646.1 761245 D 544404 CDS YP_003076647.1 254791810 8215264 762939..763646 1 NC_013008.1 hypothetical protein 763646 ybeR 8215264 ybeR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076647.1 762939 D 544404 CDS YP_003076648.1 254791811 8215265 763643..765070 1 NC_013008.1 chaperone 765070 djlB 8215265 djlB Escherichia coli O157:H7 str. TW14359 chaperone YP_003076648.1 763643 D 544404 CDS YP_003076649.1 254791812 8215266 complement(765080..765634) 1 NC_013008.1 outer membrane protein 765634 ybeT 8215266 ybeT Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003076649.1 765080 R 544404 CDS YP_003076650.1 254791813 8215267 765736..766443 1 NC_013008.1 tRNA ligase 766443 ybeU 8215267 ybeU Escherichia coli O157:H7 str. TW14359 tRNA ligase YP_003076650.1 765736 D 544404 CDS YP_003076651.1 254791814 8215268 complement(767951..769621) 1 NC_013008.1 molecular chaperone DnaK 769621 hscC 8215268 hscC Escherichia coli O157:H7 str. TW14359 molecular chaperone DnaK YP_003076651.1 767951 R 544404 CDS YP_003076652.1 254791815 8215269 complement(769705..770640) 1 NC_013008.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 770640 rihA 8215269 rihA Escherichia coli O157:H7 str. TW14359 ribonucleoside hydrolase 1 YP_003076652.1 769705 R 544404 CDS YP_003076653.1 254791816 8215270 complement(770758..771483) 1 NC_013008.1 glutamate and aspartate ABC transporter ATP-binding protein 771483 gltL 8215270 gltL Escherichia coli O157:H7 str. TW14359 glutamate and aspartate ABC transporter ATP-binding protein YP_003076653.1 770758 R 544404 CDS YP_003076654.1 254791817 8215271 complement(771483..772157) 1 NC_013008.1 glutamate and aspartate ABC transporter membrane protein 772157 gltK 8215271 gltK Escherichia coli O157:H7 str. TW14359 glutamate and aspartate ABC transporter membrane protein YP_003076654.1 771483 R 544404 CDS YP_003076655.1 254791818 8215272 complement(772157..772897) 1 NC_013008.1 glutamate and aspartate ABC transporter membrane protein 772897 gltJ 8215272 gltJ Escherichia coli O157:H7 str. TW14359 glutamate and aspartate ABC transporter membrane protein YP_003076655.1 772157 R 544404 CDS YP_003076656.1 254791819 8215273 complement(773067..773975) 1 NC_013008.1 glutamate and aspartate transporter subunit 773975 gltI 8215273 gltI Escherichia coli O157:H7 str. TW14359 glutamate and aspartate transporter subunit YP_003076656.1 773067 R 544404 CDS YP_003076657.1 254791820 8215274 complement(774372..775910) 1 NC_013008.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 775910 lnt 8215274 lnt Escherichia coli O157:H7 str. TW14359 apolipoprotein N-acyltransferase YP_003076657.1 774372 R 544404 CDS YP_003076658.1 254791821 8215275 complement(775935..776813) 1 NC_013008.1 ion transport 776813 corC 8215275 corC Escherichia coli O157:H7 str. TW14359 ion transport YP_003076658.1 775935 R 544404 CDS YP_003076659.1 254791822 8215276 complement(776903..777370) 1 NC_013008.1 metalloprotease 777370 ybeY 8215276 ybeY Escherichia coli O157:H7 str. TW14359 metalloprotease YP_003076659.1 776903 R 544404 CDS YP_003076660.1 254791823 8215277 complement(777367..778407) 1 NC_013008.1 hypothetical protein 778407 ybeZ 8215277 ybeZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076660.1 777367 R 544404 CDS YP_003076661.1 254791824 8215278 complement(778560..779984) 1 NC_013008.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 779984 miaB 8215278 miaB Escherichia coli O157:H7 str. TW14359 (dimethylallyl)adenosine tRNA methylthiotransferase YP_003076661.1 778560 R 544404 CDS YP_003076662.1 254791825 8215279 780130..781305 1 NC_013008.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 781305 ubiF 8215279 ubiF Escherichia coli O157:H7 str. TW14359 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_003076662.1 780130 D 544404 CDS YP_003076663.1 254791826 8215287 complement(782544..784208) 1 NC_013008.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 784208 asnB 8215287 asnB Escherichia coli O157:H7 str. TW14359 asparagine synthetase B YP_003076663.1 782544 R 544404 CDS YP_003076664.1 254791827 8215288 complement(784465..785217) 1 NC_013008.1 UMP phosphatase 785217 nagD 8215288 nagD Escherichia coli O157:H7 str. TW14359 UMP phosphatase YP_003076664.1 784465 R 544404 CDS YP_003076665.1 254791828 8215289 complement(785265..786485) 1 NC_013008.1 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine 786485 nagC 8215289 nagC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine YP_003076665.1 785265 R 544404 CDS YP_003076666.1 254791829 8215290 complement(786494..787642) 1 NC_013008.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 787642 nagA 8215290 nagA Escherichia coli O157:H7 str. TW14359 N-acetylglucosamine-6-phosphate deacetylase YP_003076666.1 786494 R 544404 CDS YP_003076667.1 254791830 8215291 complement(787702..788502) 1 NC_013008.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 788502 nagB 8215291 nagB Escherichia coli O157:H7 str. TW14359 glucosamine-6-phosphate deaminase YP_003076667.1 787702 R 544404 CDS YP_003076668.1 254791831 8215292 788835..790781 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 790781 nagE 8215292 nagE Escherichia coli O157:H7 str. TW14359 PTS system N-acetyl glucosamine specific transporter subunits IIABC YP_003076668.1 788835 D 544404 CDS YP_003076669.1 254791832 8215293 790984..792648 1 NC_013008.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 792648 glnS 8215293 glnS Escherichia coli O157:H7 str. TW14359 glutaminyl-tRNA synthetase YP_003076669.1 790984 D 544404 CDS YP_003076670.1 254791833 8215294 complement(792721..792915) 1 NC_013008.1 hypothetical protein 792915 8215294 ECSP_0728 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076670.1 792721 R 544404 CDS YP_003076671.1 254791834 8215296 794682..795008 1 NC_013008.1 lipoprotein 795008 ybfN 8215296 ybfN Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003076671.1 794682 D 544404 CDS YP_003076672.1 254791835 8215297 complement(795092..795538) 1 NC_013008.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 795538 fur 8215297 fur Escherichia coli O157:H7 str. TW14359 ferric uptake regulator YP_003076672.1 795092 R 544404 CDS YP_003076673.1 254791836 8215298 complement(795827..796357) 1 NC_013008.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 796357 fldA 8215298 fldA Escherichia coli O157:H7 str. TW14359 flavodoxin FldA YP_003076673.1 795827 R 544404 CDS YP_003076674.1 254791837 8215299 complement(796497..796790) 1 NC_013008.1 LexA regulated protein 796790 ybfE 8215299 ybfE Escherichia coli O157:H7 str. TW14359 LexA regulated protein YP_003076674.1 796497 R 544404 CDS YP_003076675.1 254791838 8215300 complement(796930..797694) 1 NC_013008.1 hypothetical protein 797694 ybfF 8215300 ybfF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076675.1 796930 R 544404 CDS YP_003076676.1 254791839 8215301 797879..798424 1 NC_013008.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 798424 seqA 8215301 seqA Escherichia coli O157:H7 str. TW14359 replication initiation regulator SeqA YP_003076676.1 797879 D 544404 CDS YP_003076677.1 254791840 8215302 798450..800090 1 NC_013008.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 800090 pgm 8215302 pgm Escherichia coli O157:H7 str. TW14359 phosphoglucomutase YP_003076677.1 798450 D 544404 CDS YP_003076678.1 254791841 8215303 complement(800147..801466) 1 NC_013008.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 801466 potE 8215303 potE Escherichia coli O157:H7 str. TW14359 putrescine transporter YP_003076678.1 800147 R 544404 CDS YP_003076679.1 254791842 8215304 complement(801463..803670) 1 NC_013008.1 ornithine decarboxylase 803670 speF 8215304 speF Escherichia coli O157:H7 str. TW14359 ornithine decarboxylase YP_003076679.1 801463 R 544404 CDS YP_003076680.1 254791843 8215305 complement(804055..804189) 1 NC_013008.1 hypothetical protein 804189 8215305 ECSP_0739 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076680.1 804055 R 544404 CDS YP_003076681.1 254791844 8215306 complement(804351..805028) 1 NC_013008.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 805028 kdpE 8215306 kdpE Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator KdpE YP_003076681.1 804351 R 544404 CDS YP_003076682.1 254791845 8215307 complement(805025..807709) 1 NC_013008.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 807709 kdpD 8215307 kdpD Escherichia coli O157:H7 str. TW14359 sensor protein KdpD YP_003076682.1 805025 R 544404 CDS YP_003076683.1 254791846 8215308 complement(807702..808274) 1 NC_013008.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 808274 kdpC 8215308 kdpC Escherichia coli O157:H7 str. TW14359 potassium-transporting ATPase subunit C YP_003076683.1 807702 R 544404 CDS YP_003076684.1 254791847 8215309 complement(808283..810331) 1 NC_013008.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 810331 kdpB 8215309 kdpB Escherichia coli O157:H7 str. TW14359 potassium-transporting ATPase subunit B YP_003076684.1 808283 R 544404 CDS YP_003076685.1 254791848 8215310 complement(810354..812027) 1 NC_013008.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 812027 kdpA 8215310 kdpA Escherichia coli O157:H7 str. TW14359 potassium-transporting ATPase subunit A YP_003076685.1 810354 R 544404 CDS YP_003076686.1 254791849 8215311 812429..812635 1 NC_013008.1 hypothetical protein 812635 ybfA 8215311 ybfA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076686.1 812429 D 544404 CDS YP_003076687.1 254791850 8215312 812875..817074 1 NC_013008.1 hypothetical protein 817074 ybfO 8215312 ybfO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076687.1 812875 D 544404 CDS YP_003076688.1 254791851 8215313 817098..817640 1 NC_013008.1 hypothetical protein 817640 ybfC 8215313 ybfC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076688.1 817098 D 544404 CDS YP_003076689.1 254791852 8215314 819227..820363 1 NC_013008.1 transposase 820363 8215314 ECSP_0748 Escherichia coli O157:H7 str. TW14359 transposase YP_003076689.1 819227 D 544404 CDS YP_003076690.1 254791853 8215315 820512..821021 1 NC_013008.1 hypothetical protein 821021 ybgA 8215315 ybgA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076690.1 820512 D 544404 CDS YP_003076691.1 254791854 8215316 821018..822436 1 NC_013008.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 822436 phr 8215316 phr Escherichia coli O157:H7 str. TW14359 deoxyribodipyrimidine photolyase YP_003076691.1 821018 D 544404 CDS YP_003076692.1 254791855 8215317 complement(822586..824067) 1 NC_013008.1 transporter 824067 ybgH 8215317 ybgH Escherichia coli O157:H7 str. TW14359 transporter YP_003076692.1 822586 R 544404 CDS YP_003076693.1 254791856 8215318 824338..825081 1 NC_013008.1 hydrolase-oxidase 825081 ybgI 8215318 ybgI Escherichia coli O157:H7 str. TW14359 hydrolase-oxidase YP_003076693.1 824338 D 544404 CDS YP_003076694.1 254791857 8215319 825104..825760 1 NC_013008.1 hypothetical protein 825760 ybgJ 8215319 ybgJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076694.1 825104 D 544404 CDS YP_003076695.1 254791858 8215320 825754..826686 1 NC_013008.1 hypothetical protein 826686 ybgK 8215320 ybgK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076695.1 825754 D 544404 CDS YP_003076696.1 254791859 8215321 826676..827410 1 NC_013008.1 LamB/YcsF family protein 827410 ybgL 8215321 ybgL Escherichia coli O157:H7 str. TW14359 LamB/YcsF family protein YP_003076696.1 826676 D 544404 CDS YP_003076697.1 254791860 8215322 827446..828267 1 NC_013008.1 endonuclease VIII, 5-formyluracil 828267 nei 8215322 nei Escherichia coli O157:H7 str. TW14359 endonuclease VIII, 5-formyluracil YP_003076697.1 827446 D 544404 CDS YP_003076698.1 254791861 8215323 complement(828233..829279) 1 NC_013008.1 regulator 829279 abrB 8215323 abrB Escherichia coli O157:H7 str. TW14359 regulator YP_003076698.1 828233 R 544404 CDS YP_003076699.1 254791862 8215324 complement(829428..830489) 1 NC_013008.1 fimbrial-like adhesin protein 830489 ybgO 8215324 ybgO Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076699.1 829428 R 544404 CDS YP_003076700.1 254791863 8215325 complement(830486..831217) 1 NC_013008.1 pili assembly protein 831217 ybgP 8215325 ybgP Escherichia coli O157:H7 str. TW14359 pili assembly protein YP_003076700.1 830486 R 544404 CDS YP_003076701.1 254791864 8215326 complement(831232..833682) 1 NC_013008.1 outer membrane usher protein 833682 8215326 ECSP_0760 Escherichia coli O157:H7 str. TW14359 outer membrane usher protein YP_003076701.1 831232 R 544404 CDS YP_003076702.1 254791865 8215327 complement(833741..834307) 1 NC_013008.1 fimbrial-like adhesin protein 834307 ybgD 8215327 ybgD Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076702.1 833741 R 544404 CDS YP_003076703.1 254791866 8215328 complement(834694..835977) 1 NC_013008.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 835977 gltA 8215328 gltA Escherichia coli O157:H7 str. TW14359 type II citrate synthase YP_003076703.1 834694 R 544404 CDS YP_003076704.1 254791867 8215329 836686..837075 1 NC_013008.1 succinate dehydrogenase cytochrome b556 large membrane subunit 837075 sdhC 8215329 sdhC Escherichia coli O157:H7 str. TW14359 succinate dehydrogenase cytochrome b556 large membrane subunit YP_003076704.1 836686 D 544404 CDS YP_003076705.1 254791868 8215330 837069..837416 1 NC_013008.1 succinate dehydrogenase cytochrome b556 small membrane subunit 837416 sdhD 8215330 sdhD Escherichia coli O157:H7 str. TW14359 succinate dehydrogenase cytochrome b556 small membrane subunit YP_003076705.1 837069 D 544404 CDS YP_003076706.1 254791869 8215331 837416..839182 1 NC_013008.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 839182 sdhA 8215331 sdhA Escherichia coli O157:H7 str. TW14359 succinate dehydrogenase flavoprotein subunit YP_003076706.1 837416 D 544404 CDS YP_003076707.1 254791870 8215332 839198..839914 1 NC_013008.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 839914 sdhB 8215332 sdhB Escherichia coli O157:H7 str. TW14359 succinate dehydrogenase iron-sulfur subunit YP_003076707.1 839198 D 544404 CDS YP_003076708.1 254791871 8215333 complement(839948..840079) 1 NC_013008.1 hypothetical protein 840079 8215333 ECSP_0767 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076708.1 839948 R 544404 CDS YP_003076709.1 254791872 8215334 840215..843016 1 NC_013008.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 843016 sucA 8215334 sucA Escherichia coli O157:H7 str. TW14359 2-oxoglutarate dehydrogenase E1 YP_003076709.1 840215 D 544404 CDS YP_003076710.1 254791873 8215335 843031..844248 1 NC_013008.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 844248 sucB 8215335 sucB Escherichia coli O157:H7 str. TW14359 dihydrolipoamide succinyltransferase YP_003076710.1 843031 D 544404 CDS YP_003076711.1 254791874 8215336 844342..845508 1 NC_013008.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 845508 sucC 8215336 sucC Escherichia coli O157:H7 str. TW14359 succinyl-CoA synthetase subunit beta YP_003076711.1 844342 D 544404 CDS YP_003076712.1 254791875 8215337 845508..846377 1 NC_013008.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 846377 sucD 8215337 sucD Escherichia coli O157:H7 str. TW14359 succinyl-CoA synthetase subunit alpha YP_003076712.1 845508 D 544404 CDS YP_003076713.1 254791876 8215338 846627..846773 1 NC_013008.1 histidine ammonia-lyase 846773 8215338 ECSP_0772 Escherichia coli O157:H7 str. TW14359 histidine ammonia-lyase YP_003076713.1 846627 D 544404 CDS YP_003076714.1 254791877 8215339 847044..847949 1 NC_013008.1 LysR family transcriptional regulator 847949 8215339 ECSP_0773 Escherichia coli O157:H7 str. TW14359 LysR family transcriptional regulator YP_003076714.1 847044 D 544404 CDS YP_003076715.1 254791878 8215340 complement(847983..848585) 1 NC_013008.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 848585 8215340 ECSP_0774 Escherichia coli O157:H7 str. TW14359 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_003076715.1 847983 R 544404 CDS YP_003076716.1 254791879 8215341 complement(848595..850247) 1 NC_013008.1 fumarate hydratase 850247 8215341 ECSP_0775 Escherichia coli O157:H7 str. TW14359 fumarate hydratase YP_003076716.1 848595 R 544404 CDS YP_003076717.1 254791880 8215342 complement(850355..851635) 1 NC_013008.1 symport protein 851635 8215342 ECSP_0776 Escherichia coli O157:H7 str. TW14359 symport protein YP_003076717.1 850355 R 544404 CDS YP_003076718.1 254791881 8215343 complement(851796..852113) 1 NC_013008.1 hypothetical protein 852113 8215343 ECSP_0777 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076718.1 851796 R 544404 CDS YP_003076719.1 254791882 8215344 complement(852110..853480) 1 NC_013008.1 hypothetical protein 853480 8215344 ECSP_0778 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076719.1 852110 R 544404 CDS YP_003076720.1 254791883 8215345 complement(853484..854725) 1 NC_013008.1 methylaspartate ammonia-lyase 854725 8215345 ECSP_0779 Escherichia coli O157:H7 str. TW14359 methylaspartate ammonia-lyase YP_003076720.1 853484 R 544404 CDS YP_003076721.1 254791884 8215346 complement(854725..856170) 1 NC_013008.1 glutamate mutase subumit E 856170 8215346 ECSP_0780 Escherichia coli O157:H7 str. TW14359 glutamate mutase subumit E YP_003076721.1 854725 R 544404 CDS YP_003076722.1 254791885 8215347 complement(856189..857577) 1 NC_013008.1 hypothetical protein 857577 8215347 ECSP_0781 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076722.1 856189 R 544404 CDS YP_003076723.1 254791886 8215348 complement(857577..858026) 1 NC_013008.1 converts methylaspartate to L-glutamate; methylaspartate mutase subunit S 858026 8215348 ECSP_0782 Escherichia coli O157:H7 str. TW14359 methylaspartate mutase subunit S YP_003076723.1 857577 R 544404 CDS YP_003076724.1 254791887 8215349 complement(858213..858380) 1 NC_013008.1 hypothetical protein 858380 8215349 ECSP_0783 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076724.1 858213 R 544404 CDS YP_003076725.1 254791888 8215350 complement(858574..858996) 1 NC_013008.1 hypothetical protein 858996 8215350 ECSP_0784 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076725.1 858574 R 544404 CDS YP_003076726.1 254791889 8215351 complement(859078..860022) 1 NC_013008.1 hypothetical protein 860022 8215351 ECSP_0785 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076726.1 859078 R 544404 CDS YP_003076727.1 254791890 8215352 860828..862396 1 NC_013008.1 cytochrome d terminal oxidase subunit I 862396 cydA 8215352 cydA Escherichia coli O157:H7 str. TW14359 cytochrome d terminal oxidase subunit I YP_003076727.1 860828 D 544404 CDS YP_003076728.1 254791891 8215353 862412..863551 1 NC_013008.1 cytochrome d terminal oxidase subunit II 863551 cydB 8215353 cydB Escherichia coli O157:H7 str. TW14359 cytochrome d terminal oxidase subunit II YP_003076728.1 862412 D 544404 CDS YP_003076729.1 254791892 8215354 863679..863972 1 NC_013008.1 hypothetical protein 863972 ybgE 8215354 ybgE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076729.1 863679 D 544404 CDS YP_003076730.1 254791893 8215355 864122..864526 1 NC_013008.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 864526 ybgC 8215355 ybgC Escherichia coli O157:H7 str. TW14359 acyl-CoA thioester hydrolase YP_003076730.1 864122 D 544404 CDS YP_003076731.1 254791894 8215356 864523..865215 1 NC_013008.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 865215 tolQ 8215356 tolQ Escherichia coli O157:H7 str. TW14359 colicin uptake protein TolQ YP_003076731.1 864523 D 544404 CDS YP_003076732.1 254791895 8215357 865219..865647 1 NC_013008.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 865647 tolR 8215357 tolR Escherichia coli O157:H7 str. TW14359 colicin uptake protein TolR YP_003076732.1 865219 D 544404 CDS YP_003076733.1 254791896 8215358 865712..866986 1 NC_013008.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 866986 tolA 8215358 tolA Escherichia coli O157:H7 str. TW14359 cell envelope integrity inner membrane protein TolA YP_003076733.1 865712 D 544404 CDS YP_003076734.1 254791897 8215359 867119..868411 1 NC_013008.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 868411 tolB 8215359 tolB Escherichia coli O157:H7 str. TW14359 translocation protein TolB YP_003076734.1 867119 D 544404 CDS YP_003076735.1 254791898 8215360 868446..868967 1 NC_013008.1 peptidoglycan-associated outer membrane lipoprotein 868967 pal 8215360 pal Escherichia coli O157:H7 str. TW14359 peptidoglycan-associated outer membrane lipoprotein YP_003076735.1 868446 D 544404 CDS YP_003076736.1 254791899 8215361 868977..869768 1 NC_013008.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 869768 ybgF 8215361 ybgF Escherichia coli O157:H7 str. TW14359 tol-pal system protein YbgF YP_003076736.1 868977 D 544404 CDS YP_003076737.1 254791900 8215368 870903..871946 1 NC_013008.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 871946 nadA 8215368 nadA Escherichia coli O157:H7 str. TW14359 quinolinate synthetase YP_003076737.1 870903 D 544404 CDS YP_003076738.1 254791901 8215369 871984..872703 1 NC_013008.1 nicotinamide mononucleotide transporter 872703 pnuC 8215369 pnuC Escherichia coli O157:H7 str. TW14359 nicotinamide mononucleotide transporter YP_003076738.1 871984 D 544404 CDS YP_003076739.1 254791902 8215370 complement(872700..873641) 1 NC_013008.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 873641 zitB 8215370 zitB Escherichia coli O157:H7 str. TW14359 zinc transporter ZitB YP_003076739.1 872700 R 544404 CDS YP_003076740.1 254791903 8215371 complement(873755..874135) 1 NC_013008.1 hypothetical protein 874135 ybgS 8215371 ybgS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076740.1 873755 R 544404 CDS YP_003076741.1 254791904 8215372 874451..875503 1 NC_013008.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 875503 aroG 8215372 aroG Escherichia coli O157:H7 str. TW14359 phospho-2-dehydro-3-deoxyheptonate aldolase YP_003076741.1 874451 D 544404 CDS YP_003076742.1 254791905 8215373 complement(875669..876421) 1 NC_013008.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 876421 gpmA 8215373 gpmA Escherichia coli O157:H7 str. TW14359 phosphoglyceromutase YP_003076742.1 875669 R 544404 CDS YP_003076743.1 254791906 8215374 complement(876495..876623) 1 NC_013008.1 hypothetical protein 876623 8215374 ECSP_0808 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076743.1 876495 R 544404 CDS YP_003076744.1 254791907 8215375 complement(876623..877663) 1 NC_013008.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 877663 galM 8215375 galM Escherichia coli O157:H7 str. TW14359 aldose 1-epimerase YP_003076744.1 876623 R 544404 CDS YP_003076745.1 254791908 8215376 complement(877657..878805) 1 NC_013008.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 878805 galK 8215376 galK Escherichia coli O157:H7 str. TW14359 galactokinase YP_003076745.1 877657 R 544404 CDS YP_003076746.1 254791909 8215377 complement(878809..879855) 1 NC_013008.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 879855 galT 8215377 galT Escherichia coli O157:H7 str. TW14359 galactose-1-phosphate uridylyltransferase YP_003076746.1 878809 R 544404 CDS YP_003076747.1 254791910 8215378 complement(879865..880881) 1 NC_013008.1 UDP-galactose-4-epimerase 880881 galE 8215378 galE Escherichia coli O157:H7 str. TW14359 UDP-galactose-4-epimerase YP_003076747.1 879865 R 544404 CDS YP_003076748.1 254791911 8215379 complement(881143..882615) 1 NC_013008.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 882615 modF 8215379 modF Escherichia coli O157:H7 str. TW14359 molybdenum transport ATP-binding protein ModF YP_003076748.1 881143 R 544404 CDS YP_003076749.1 254791912 8215380 complement(882683..883471) 1 NC_013008.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 883471 modE 8215380 modE Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator ModE YP_003076749.1 882683 R 544404 CDS YP_003076750.1 254791913 8215381 883600..883749 1 NC_013008.1 hypothetical protein 883749 ybhT 8215381 ybhT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076750.1 883600 D 544404 CDS YP_003076751.1 254791914 8215382 883916..884689 1 NC_013008.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 884689 modA 8215382 modA Escherichia coli O157:H7 str. TW14359 molybdate transporter periplasmic protein YP_003076751.1 883916 D 544404 CDS YP_003076752.1 254791915 8215383 884689..885378 1 NC_013008.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 885378 modB 8215383 modB Escherichia coli O157:H7 str. TW14359 molybdate ABC transporter permease YP_003076752.1 884689 D 544404 CDS YP_003076753.1 254791916 8215384 885381..886439 1 NC_013008.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 886439 modC 8215384 modC Escherichia coli O157:H7 str. TW14359 molybdate transporter ATP-binding protein YP_003076753.1 885381 D 544404 CDS YP_003076754.1 254791917 8215385 complement(886440..887258) 1 NC_013008.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 887258 ybhA 8215385 ybhA Escherichia coli O157:H7 str. TW14359 phosphotransferase YP_003076754.1 886440 R 544404 CDS YP_003076755.1 254791918 8215386 887413..888408 1 NC_013008.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 888408 pgl 8215386 pgl Escherichia coli O157:H7 str. TW14359 6-phosphogluconolactonase YP_003076755.1 887413 D 544404 CDS YP_003076756.1 254791919 8215387 complement(888449..889402) 1 NC_013008.1 DNA-binding transcriptional regulator 889402 ybhD 8215387 ybhD Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076756.1 888449 R 544404 CDS YP_003076757.1 254791920 8215388 889586..890638 1 NC_013008.1 hypothetical protein 890638 ybhH 8215388 ybhH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076757.1 889586 D 544404 CDS YP_003076758.1 254791921 8215389 890714..892147 1 NC_013008.1 transporter 892147 ybhI 8215389 ybhI Escherichia coli O157:H7 str. TW14359 transporter YP_003076758.1 890714 D 544404 CDS YP_003076759.1 254791922 8215390 892330..894591 1 NC_013008.1 hypothetical protein 894591 ybhJ 8215390 ybhJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076759.1 892330 D 544404 CDS YP_003076760.1 254791923 8215391 complement(894732..896015) 1 NC_013008.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase 896015 ybhC 8215391 ybhC Escherichia coli O157:H7 str. TW14359 pectinesterase YP_003076760.1 894732 R 544404 CDS YP_003076761.1 254791924 8215392 complement(896150..896920) 1 NC_013008.1 integrase encoded by prophage CP-933K 896920 8215392 ECSP_0826 Escherichia coli O157:H7 str. TW14359 integrase encoded by prophage CP-933K YP_003076761.1 896150 R 544404 CDS YP_003076762.1 254791925 8215393 complement(897198..897416) 1 NC_013008.1 excisionase 897416 8215393 ECSP_0827 Escherichia coli O157:H7 str. TW14359 excisionase YP_003076762.1 897198 R 544404 CDS YP_003076763.1 254791926 8215394 complement(897456..897623) 1 NC_013008.1 hypothetical protein 897623 8215394 ECSP_0828 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076763.1 897456 R 544404 CDS YP_003076764.1 254791927 8215395 897866..898468 1 NC_013008.1 hypothetical protein 898468 8215395 ECSP_0829 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076764.1 897866 D 544404 CDS YP_003076765.1 254791928 8215396 complement(898999..899214) 1 NC_013008.1 hypothetical protein 899214 8215396 ECSP_0830 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076765.1 898999 R 544404 CDS YP_003076766.1 254791929 8215397 complement(899291..899482) 1 NC_013008.1 hypothetical protein 899482 8215397 ECSP_0831 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076766.1 899291 R 544404 CDS YP_003076767.1 254791930 8215398 complement(899634..900314) 1 NC_013008.1 exonuclease encoded by prophage CP-933K 900314 8215398 ECSP_0832 Escherichia coli O157:H7 str. TW14359 exonuclease encoded by prophage CP-933K YP_003076767.1 899634 R 544404 CDS YP_003076768.1 254791931 8215399 complement(900311..900958) 1 NC_013008.1 Bet recombination protein of prophage CP-933K 900958 8215399 ECSP_0833 Escherichia coli O157:H7 str. TW14359 Bet recombination protein of prophage CP-933K YP_003076768.1 900311 R 544404 CDS YP_003076769.1 254791932 8215400 901351..901974 1 NC_013008.1 hypothetical protein 901974 8215400 ECSP_0834 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076769.1 901351 D 544404 CDS YP_003076770.1 254791933 8215401 902205..902636 1 NC_013008.1 hypothetical protein 902636 8215401 ECSP_0835 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076770.1 902205 D 544404 CDS YP_003076771.1 254791934 8215402 complement(902848..903807) 1 NC_013008.1 hypothetical protein 903807 8215402 ECSP_0836 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076771.1 902848 R 544404 CDS YP_003076772.1 254791935 8215403 904282..904971 1 NC_013008.1 antiterminator Q protein of prophage CP-933K 904971 8215403 ECSP_0837 Escherichia coli O157:H7 str. TW14359 antiterminator Q protein of prophage CP-933K YP_003076772.1 904282 D 544404 CDS YP_003076773.1 254791936 8215404 905182..905898 1 NC_013008.1 hypothetical protein 905898 8215404 ECSP_0838 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076773.1 905182 D 544404 CDS YP_003076774.1 254791937 8215405 906041..906142 1 NC_013008.1 hypothetical protein 906142 8215405 ECSP_0839 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076774.1 906041 D 544404 CDS YP_003076776.1 254791939 8215407 906979..907476 1 NC_013008.1 lysozyme protein R of prophage CP-933K 907476 8215407 ECSP_0841 Escherichia coli O157:H7 str. TW14359 lysozyme protein R of prophage CP-933K YP_003076776.1 906979 D 544404 CDS YP_003076777.1 254791940 8215408 907473..907940 1 NC_013008.1 endopeptidase protein Rz of prophage CP-933K 907940 8215408 ECSP_0842 Escherichia coli O157:H7 str. TW14359 endopeptidase protein Rz of prophage CP-933K YP_003076777.1 907473 D 544404 CDS YP_003076778.1 254791941 8215409 complement(908439..908624) 1 NC_013008.1 hypothetical protein 908624 8215409 ECSP_0843 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076778.1 908439 R 544404 CDS YP_003076779.1 254791942 8215410 908755..909246 1 NC_013008.1 hypothetical protein 909246 8215410 ECSP_0844 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076779.1 908755 D 544404 CDS YP_003076780.1 254791943 8215411 909246..911348 1 NC_013008.1 DNA packaging protein of prophage CP-933K 911348 8215411 ECSP_0845 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933K YP_003076780.1 909246 D 544404 CDS YP_003076781.1 254791944 8215412 911485..912609 1 NC_013008.1 hypothetical protein 912609 8215412 ECSP_0846 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076781.1 911485 D 544404 CDS YP_003076782.1 254791945 8215413 912704..913066 1 NC_013008.1 hypothetical protein 913066 8215413 ECSP_0847 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076782.1 912704 D 544404 CDS YP_003076783.1 254791946 8215414 913080..915038 1 NC_013008.1 protease encoded in prophage CP-933K 915038 8215414 ECSP_0848 Escherichia coli O157:H7 str. TW14359 protease encoded in prophage CP-933K YP_003076783.1 913080 D 544404 CDS YP_003076784.1 254791947 8215415 915125..915448 1 NC_013008.1 hypothetical protein 915448 8215415 ECSP_0849 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076784.1 915125 D 544404 CDS YP_003076785.1 254791948 8215416 915441..915716 1 NC_013008.1 hypothetical protein 915716 8215416 ECSP_0850 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076785.1 915441 D 544404 CDS YP_003076786.1 254791949 8215417 915728..916306 1 NC_013008.1 tail component of prophage CP-933K 916306 8215417 ECSP_0851 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076786.1 915728 D 544404 CDS YP_003076787.1 254791950 8215418 916303..916704 1 NC_013008.1 tail component of prophage CP-933K 916704 8215418 ECSP_0852 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076787.1 916303 D 544404 CDS YP_003076788.1 254791951 8215419 916715..917458 1 NC_013008.1 tail component of prophage CP-933K 917458 8215419 ECSP_0853 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076788.1 916715 D 544404 CDS YP_003076789.1 254791952 8215420 917516..917905 1 NC_013008.1 tail component of prophage CP-933K 917905 8215420 ECSP_0854 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076789.1 917516 D 544404 CDS YP_003076790.1 254791953 8215421 917914..918243 1 NC_013008.1 tail component of prophage CP-933K 918243 8215421 ECSP_0855 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076790.1 917914 D 544404 CDS YP_003076791.1 254791954 8215422 918215..921280 1 NC_013008.1 tail component of prophage CP-933K 921280 8215422 ECSP_0856 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076791.1 918215 D 544404 CDS YP_003076792.1 254791955 8215423 921280..921609 1 NC_013008.1 tail component of prophage CP-933K 921609 8215423 ECSP_0857 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076792.1 921280 D 544404 CDS YP_003076793.1 254791956 8215424 921619..922317 1 NC_013008.1 tail component of prophage CP-933K 922317 8215424 ECSP_0858 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076793.1 921619 D 544404 CDS YP_003076794.1 254791957 8215425 922323..923066 1 NC_013008.1 tail component of prophage CP-933K 923066 8215425 ECSP_0859 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076794.1 922323 D 544404 CDS YP_003076795.1 254791958 8215426 922964..923611 1 NC_013008.1 tail component of prophage CP-933K 923611 8215426 ECSP_0860 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076795.1 922964 D 544404 CDS YP_003076796.1 254791959 8215427 923672..927085 1 NC_013008.1 tail component of prophage CP-933K 927085 8215427 ECSP_0861 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076796.1 923672 D 544404 CDS YP_003076797.1 254791960 8215428 927156..927755 1 NC_013008.1 outer membrane protein of prophage CP-933K 927755 lomK 8215428 lomK Escherichia coli O157:H7 str. TW14359 outer membrane protein of prophage CP-933K YP_003076797.1 927156 D 544404 CDS YP_003076798.1 254791961 8215429 927815..929131 1 NC_013008.1 tail component of prophage CP-933K 929131 8215429 ECSP_0863 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933K YP_003076798.1 927815 D 544404 CDS YP_003076799.1 254791962 8215430 929094..929402 1 NC_013008.1 hypothetical protein 929402 8215430 ECSP_0864 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076799.1 929094 D 544404 CDS YP_003076800.1 254791963 8215431 929579..930559 1 NC_013008.1 non-LEE-encoded type III effector 930559 nleB1 8215431 nleB1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076800.1 929579 D 544404 CDS YP_003076801.1 254791964 8215432 930620..931612 1 NC_013008.1 non-LEE-encoded type III effector 931612 nleC 8215432 nleC Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076801.1 930620 D 544404 CDS YP_003076802.1 254791965 8215433 932440..933321 1 NC_013008.1 non-LEE-encoded type III effector 933321 nleH1 8215433 nleH1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076802.1 932440 D 544404 CDS YP_003076803.1 254791966 8215434 933552..934250 1 NC_013008.1 non-LEE-encoded type III effector 934250 nleD 8215434 nleD Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076803.1 933552 D 544404 CDS YP_003076804.1 254791967 8215435 complement(934757..935233) 1 NC_013008.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 935233 ybhB 8215435 ybhB Escherichia coli O157:H7 str. TW14359 kinase inhibitor protein YP_003076804.1 934757 R 544404 CDS YP_003076805.1 254791968 8215436 complement(935292..936581) 1 NC_013008.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 936581 bioA 8215436 bioA Escherichia coli O157:H7 str. TW14359 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_003076805.1 935292 R 544404 CDS YP_003076806.1 254791969 8215437 936668..937708 1 NC_013008.1 biotin synthase 937708 bioB 8215437 bioB Escherichia coli O157:H7 str. TW14359 biotin synthase YP_003076806.1 936668 D 544404 CDS YP_003076807.1 254791970 8215438 937705..938859 1 NC_013008.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 938859 bioF 8215438 bioF Escherichia coli O157:H7 str. TW14359 8-amino-7-oxononanoate synthase YP_003076807.1 937705 D 544404 CDS YP_003076808.1 254791971 8215439 938846..939601 1 NC_013008.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 939601 bioC 8215439 bioC Escherichia coli O157:H7 str. TW14359 biotin biosynthesis protein BioC YP_003076808.1 938846 D 544404 CDS YP_003076809.1 254791972 8215440 939594..940271 1 NC_013008.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 940271 bioD 8215440 bioD Escherichia coli O157:H7 str. TW14359 dithiobiotin synthetase YP_003076809.1 939594 D 544404 CDS YP_003076810.1 254791973 8215441 940850..942871 1 NC_013008.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 942871 uvrB 8215441 uvrB Escherichia coli O157:H7 str. TW14359 excinuclease ABC subunit B YP_003076810.1 940850 D 544404 CDS YP_003076811.1 254791974 8215442 complement(943062..943970) 1 NC_013008.1 transferase with NAD(P)-binding Rossmann-fold domain 943970 ybhK 8215442 ybhK Escherichia coli O157:H7 str. TW14359 transferase with NAD(P)-binding Rossmann-fold domain YP_003076811.1 943062 R 544404 CDS YP_003076812.1 254791975 8215443 944367..945356 1 NC_013008.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 945356 moaA 8215443 moaA Escherichia coli O157:H7 str. TW14359 molybdenum cofactor biosynthesis protein A YP_003076812.1 944367 D 544404 CDS YP_003076813.1 254791976 8215444 945378..945890 1 NC_013008.1 molybdopterin biosynthesis protein B 945890 moaB 8215444 moaB Escherichia coli O157:H7 str. TW14359 molybdopterin biosynthesis protein B YP_003076813.1 945378 D 544404 CDS YP_003076814.1 254791977 8215445 945893..946378 1 NC_013008.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 946378 moaC 8215445 moaC Escherichia coli O157:H7 str. TW14359 molybdenum cofactor biosynthesis protein MoaC YP_003076814.1 945893 D 544404 CDS YP_003076815.1 254791978 8215446 946371..946616 1 NC_013008.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 946616 moaD 8215446 moaD Escherichia coli O157:H7 str. TW14359 molybdopterin synthase small subunit YP_003076815.1 946371 D 544404 CDS YP_003076816.1 254791979 8215447 946618..947070 1 NC_013008.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 947070 moaE 8215447 moaE Escherichia coli O157:H7 str. TW14359 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_003076816.1 946618 D 544404 CDS YP_003076817.1 254791980 8215448 947206..947910 1 NC_013008.1 inner membrane protein 947910 ybhL 8215448 ybhL Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076817.1 947206 D 544404 CDS YP_003076818.1 254791981 8215449 948118..948831 1 NC_013008.1 hypothetical protein 948831 ybhM 8215449 ybhM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076818.1 948118 D 544404 CDS YP_003076819.1 254791982 8215450 complement(948867..949823) 1 NC_013008.1 hypothetical protein 949823 ybhN 8215450 ybhN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076819.1 948867 R 544404 CDS YP_003076820.1 254791983 8215451 complement(949823..951064) 1 NC_013008.1 cardiolipin synthase 2 951064 ybhO 8215451 ybhO Escherichia coli O157:H7 str. TW14359 cardiolipin synthase 2 YP_003076820.1 949823 R 544404 CDS YP_003076821.1 254791984 8215452 complement(951061..951822) 1 NC_013008.1 DNase 951822 ybhP 8215452 ybhP Escherichia coli O157:H7 str. TW14359 DNase YP_003076821.1 951061 R 544404 CDS YP_003076822.1 254791985 8215453 951955..952365 1 NC_013008.1 inner membrane protein 952365 ybhQ 8215453 ybhQ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076822.1 951955 D 544404 CDS YP_003076823.1 254791986 8215454 complement(952327..953433) 1 NC_013008.1 ABC transporter membrane protein 953433 ybhR 8215454 ybhR Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003076823.1 952327 R 544404 CDS YP_003076824.1 254791987 8215455 complement(953444..954577) 1 NC_013008.1 ABC transporter membrane protein 954577 ybhS 8215455 ybhS Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003076824.1 953444 R 544404 CDS YP_003076825.1 254791988 8215456 complement(954570..956306) 1 NC_013008.1 fused transporter subunits of ABC superfamily: ATP-binding proteins 956306 ybhF 8215456 ybhF Escherichia coli O157:H7 str. TW14359 fused transporter subunits of ABC superfamily: ATP-binding proteins YP_003076825.1 954570 R 544404 CDS YP_003076826.1 254791989 8215457 complement(956299..957297) 1 NC_013008.1 hypothetical protein 957297 ybhG 8215457 ybhG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076826.1 956299 R 544404 CDS YP_003076827.1 254791990 8215458 complement(957297..957968) 1 NC_013008.1 DNA-binding transcriptional regulator 957968 ybiH 8215458 ybiH Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076827.1 957297 R 544404 CDS YP_003076828.1 254791991 8215459 958197..959564 1 NC_013008.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 959564 rhlE 8215459 rhlE Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase RhlE YP_003076828.1 958197 D 544404 CDS YP_003076829.1 254791992 8215460 959716..959859 1 NC_013008.1 hypothetical protein 959859 8215460 ECSP_0894 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076829.1 959716 D 544404 CDS YP_003076830.1 254791993 8215461 960172..962184 1 NC_013008.1 non-LEE-encoded type III effector 962184 espX2 8215461 espX2 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003076830.1 960172 D 544404 CDS YP_003076831.1 254791994 8215462 962468..964618 1 NC_013008.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 964618 dinG 8215462 dinG Escherichia coli O157:H7 str. TW14359 ATP-dependent DNA helicase DinG YP_003076831.1 962468 D 544404 CDS YP_003076832.1 254791995 8215463 964646..965608 1 NC_013008.1 glycosyl transferase family protein 965608 ybiB 8215463 ybiB Escherichia coli O157:H7 str. TW14359 glycosyl transferase family protein YP_003076832.1 964646 D 544404 CDS YP_003076833.1 254791996 8215464 965749..966834 1 NC_013008.1 hypothetical protein 966834 ybiC 8215464 ybiC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076833.1 965749 D 544404 CDS YP_003076834.1 254791997 8215465 complement(967063..967323) 1 NC_013008.1 hypothetical protein 967323 ybiJ 8215465 ybiJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076834.1 967063 R 544404 CDS YP_003076835.1 254791998 8215466 complement(967566..967943) 1 NC_013008.1 hypothetical protein 967943 ybiI 8215466 ybiI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076835.1 967566 R 544404 CDS YP_003076836.1 254791999 8215467 complement(967928..968614) 1 NC_013008.1 hydroxylase 968614 ybiX 8215467 ybiX Escherichia coli O157:H7 str. TW14359 hydroxylase YP_003076836.1 967928 R 544404 CDS YP_003076837.1 254792000 8215468 complement(968656..970938) 1 NC_013008.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 970938 fiu 8215468 fiu Escherichia coli O157:H7 str. TW14359 catecholate siderophore receptor Fiu YP_003076837.1 968656 R 544404 CDS YP_003076838.1 254792001 8215469 complement(971203..971463) 1 NC_013008.1 hypothetical protein 971463 ybiM 8215469 ybiM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076838.1 971203 R 544404 CDS YP_003076839.1 254792002 8215470 971739..972665 1 NC_013008.1 SAM-dependent methyltransferase 972665 ybiN 8215470 ybiN Escherichia coli O157:H7 str. TW14359 SAM-dependent methyltransferase YP_003076839.1 971739 D 544404 CDS YP_003076840.1 254792003 8215471 complement(972662..974887) 1 NC_013008.1 hypothetical protein 974887 ybiO 8215471 ybiO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076840.1 972662 R 544404 CDS YP_003076841.1 254792004 8215472 complement(975004..975726) 1 NC_013008.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 975726 glnQ 8215472 glnQ Escherichia coli O157:H7 str. TW14359 glutamine ABC transporter ATP-binding protein YP_003076841.1 975004 R 544404 CDS YP_003076842.1 254792005 8215473 complement(975723..976382) 1 NC_013008.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 976382 glnP 8215473 glnP Escherichia coli O157:H7 str. TW14359 glutamine ABC transporter permease YP_003076842.1 975723 R 544404 CDS YP_003076843.1 254792006 8215474 complement(976520..977266) 1 NC_013008.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 977266 glnH 8215474 glnH Escherichia coli O157:H7 str. TW14359 glutamine ABC transporter periplasmic protein YP_003076843.1 976520 R 544404 CDS YP_003076844.1 254792007 8215475 complement(977670..978173) 1 NC_013008.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 978173 dps 8215475 dps Escherichia coli O157:H7 str. TW14359 DNA starvation/stationary phase protection protein Dps YP_003076844.1 977670 R 544404 CDS YP_003076845.1 254792008 8215476 complement(978343..978441) 1 NC_013008.1 hypothetical protein 978441 8215476 ECSP_0910 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076845.1 978343 R 544404 CDS YP_003076846.1 254792009 8215477 complement(978472..979359) 1 NC_013008.1 threonine and homoserine efflux system 979359 rhtA 8215477 rhtA Escherichia coli O157:H7 str. TW14359 threonine and homoserine efflux system YP_003076846.1 978472 R 544404 CDS YP_003076847.1 254792010 8215478 979712..980227 1 NC_013008.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 980227 ompX 8215478 ompX Escherichia coli O157:H7 str. TW14359 outer membrane protein X YP_003076847.1 979712 D 544404 CDS YP_003076848.1 254792011 8215479 complement(980276..981859) 1 NC_013008.1 hydrolase 981859 ybiP 8215479 ybiP Escherichia coli O157:H7 str. TW14359 hydrolase YP_003076848.1 980276 R 544404 CDS YP_003076849.1 254792012 8215480 complement(982131..982259) 1 NC_013008.1 hypothetical protein 982259 8215480 ECSP_0914 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076849.1 982131 R 544404 CDS YP_003076850.1 254792013 8215481 982445..982912 1 NC_013008.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 982912 mntR 8215481 mntR Escherichia coli O157:H7 str. TW14359 manganese transport regulator MntR YP_003076850.1 982445 D 544404 CDS YP_003076851.1 254792014 8215482 982909..984027 1 NC_013008.1 transporter 984027 ybiR 8215482 ybiR Escherichia coli O157:H7 str. TW14359 transporter YP_003076851.1 982909 D 544404 CDS YP_003076852.1 254792015 8215483 complement(984085..985005) 1 NC_013008.1 hypothetical protein 985005 ybiS 8215483 ybiS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076852.1 984085 R 544404 CDS YP_003076853.1 254792016 8215484 985224..986816 1 NC_013008.1 ABC transporter with two ATP-binding domains 986816 ybiT 8215484 ybiT Escherichia coli O157:H7 str. TW14359 ABC transporter with two ATP-binding domains YP_003076853.1 985224 D 544404 CDS YP_003076854.1 254792017 8215485 complement(986984..988249) 1 NC_013008.1 hypothetical protein 988249 ybiU 8215485 ybiU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076854.1 986984 R 544404 CDS YP_003076855.1 254792018 8215486 complement(988401..989216) 1 NC_013008.1 hydrolase 989216 ybiV 8215486 ybiV Escherichia coli O157:H7 str. TW14359 hydrolase YP_003076855.1 988401 R 544404 CDS YP_003076856.1 254792019 8215488 complement(991799..992698) 1 NC_013008.1 pyruvate formate lyase activating enzyme 992698 ybiY 8215488 ybiY Escherichia coli O157:H7 str. TW14359 pyruvate formate lyase activating enzyme YP_003076856.1 991799 R 544404 CDS YP_003076857.1 254792020 8215489 992829..993491 1 NC_013008.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 993491 fsaA 8215489 fsaA Escherichia coli O157:H7 str. TW14359 fructose-6-phosphate aldolase YP_003076857.1 992829 D 544404 CDS YP_003076858.1 254792021 8215490 complement(993670..994419) 1 NC_013008.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 994419 moeB 8215490 moeB Escherichia coli O157:H7 str. TW14359 molybdopterin biosynthesis protein MoeB YP_003076858.1 993670 R 544404 CDS YP_003076859.1 254792022 8215491 complement(994419..995654) 1 NC_013008.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 995654 moeA 8215491 moeA Escherichia coli O157:H7 str. TW14359 molybdopterin biosynthesis protein MoeA YP_003076859.1 994419 R 544404 CDS YP_003076860.1 254792023 8215493 996810..998681 1 NC_013008.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 998681 8215493 ECSP_0927 Escherichia coli O157:H7 str. TW14359 glutathione transporter ATP-binding protein YP_003076860.1 996810 D 544404 CDS YP_003076861.1 254792024 8215494 998701..1000239 1 NC_013008.1 transport protein 1000239 8215494 ECSP_0928 Escherichia coli O157:H7 str. TW14359 transport protein YP_003076861.1 998701 D 544404 CDS YP_003076862.1 254792025 8215495 1000257..1001177 1 NC_013008.1 transport system permease 1001177 8215495 ECSP_0929 Escherichia coli O157:H7 str. TW14359 transport system permease YP_003076862.1 1000257 D 544404 CDS YP_003076863.1 254792026 8215496 1001180..1002091 1 NC_013008.1 transport system permease 1002091 8215496 ECSP_0930 Escherichia coli O157:H7 str. TW14359 transport system permease YP_003076863.1 1001180 D 544404 CDS YP_003076864.1 254792027 8215497 1002269..1004617 1 NC_013008.1 hypothetical protein 1004617 yliE 8215497 yliE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076864.1 1002269 D 544404 CDS YP_003076865.1 254792028 8215498 1004625..1005953 1 NC_013008.1 diguanylate cyclase 1005953 yliF 8215498 yliF Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003076865.1 1004625 D 544404 CDS YP_003076866.1 254792029 8215499 complement(1006023..1006352) 1 NC_013008.1 hypothetical protein 1006352 8215499 ECSP_0933 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076866.1 1006023 R 544404 CDS YP_003076867.1 254792030 8215500 complement(1006342..1006728) 1 NC_013008.1 hypothetical protein 1006728 8215500 ECSP_0934 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076867.1 1006342 R 544404 CDS YP_003076868.1 254792031 8215501 complement(1006954..1008279) 1 NC_013008.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 1008279 rimO 8215501 rimO Escherichia coli O157:H7 str. TW14359 ribosomal protein S12 methylthiotransferase YP_003076868.1 1006954 R 544404 CDS YP_003076869.1 254792032 8215502 1008492..1008875 1 NC_013008.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1008875 bssR 8215502 bssR Escherichia coli O157:H7 str. TW14359 biofilm formation regulatory protein BssR YP_003076869.1 1008492 D 544404 CDS YP_003076870.1 254792033 8215503 1008986..1010101 1 NC_013008.1 dehydrogenase 1010101 yliI 8215503 yliI Escherichia coli O157:H7 str. TW14359 dehydrogenase YP_003076870.1 1008986 D 544404 CDS YP_003076871.1 254792034 8215504 complement(1010098..1010724) 1 NC_013008.1 glutathione S-transferase 1010724 yliJ 8215504 yliJ Escherichia coli O157:H7 str. TW14359 glutathione S-transferase YP_003076871.1 1010098 R 544404 CDS YP_003076872.1 254792035 8215505 1010970..1012172 1 NC_013008.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 1012172 dacC 8215505 dacC Escherichia coli O157:H7 str. TW14359 D-alanyl-D-alanine carboxypeptidase fraction C YP_003076872.1 1010970 D 544404 CDS YP_003076873.1 254792036 8215506 complement(1012219..1012977) 1 NC_013008.1 DNA-binding transcriptional repressor DeoR 1012977 deoR 8215506 deoR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor DeoR YP_003076873.1 1012219 R 544404 CDS YP_003076874.1 254792037 8215507 complement(1013035..1013631) 1 NC_013008.1 UDP pyrophosphate phosphatase 1013631 ybjG 8215507 ybjG Escherichia coli O157:H7 str. TW14359 UDP pyrophosphate phosphatase YP_003076874.1 1013035 R 544404 CDS YP_003076875.1 254792038 8215508 1013916..1015148 1 NC_013008.1 multidrug efflux system protein 1015148 cmr 8215508 cmr Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein YP_003076875.1 1013916 D 544404 CDS YP_003076876.1 254792039 8215509 complement(1015189..1015473) 1 NC_013008.1 hypothetical protein 1015473 ybjH 8215509 ybjH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076876.1 1015189 R 544404 CDS YP_003076877.1 254792040 8215510 complement(1015559..1016374) 1 NC_013008.1 hypothetical protein 1016374 ybjI 8215510 ybjI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076877.1 1015559 R 544404 CDS YP_003076878.1 254792041 8215511 complement(1016374..1017582) 1 NC_013008.1 transporter 1017582 ybjJ 8215511 ybjJ Escherichia coli O157:H7 str. TW14359 transporter YP_003076878.1 1016374 R 544404 CDS YP_003076879.1 254792042 8215512 1017666..1018202 1 NC_013008.1 DNA-binding transcriptional regulator 1018202 ybjK 8215512 ybjK Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003076879.1 1017666 D 544404 CDS YP_003076880.1 254792043 8215513 complement(1018377..1020062) 1 NC_013008.1 hypothetical protein 1020062 ybjL 8215513 ybjL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076880.1 1018377 R 544404 CDS YP_003076881.1 254792044 8215514 1020332..1020709 1 NC_013008.1 inner membrane protein 1020709 ybjM 8215514 ybjM Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076881.1 1020332 D 544404 CDS YP_003076882.1 254792045 8215515 complement(1020739..1020996) 1 NC_013008.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 1020996 grxA 8215515 grxA Escherichia coli O157:H7 str. TW14359 glutaredoxin 1 YP_003076882.1 1020739 R 544404 CDS YP_003076883.1 254792046 8215516 1021156..1021443 1 NC_013008.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1021443 ybjC 8215516 ybjC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076883.1 1021156 D 544404 CDS YP_003076884.1 254792047 8215517 1021427..1022149 1 NC_013008.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1022149 nfsA 8215517 nfsA Escherichia coli O157:H7 str. TW14359 nitroreductase A YP_003076884.1 1021427 D 544404 CDS YP_003076885.1 254792048 8215518 1022210..1023112 1 NC_013008.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1023112 rimK 8215518 rimK Escherichia coli O157:H7 str. TW14359 ribosomal protein S6 modification protein YP_003076885.1 1022210 D 544404 CDS YP_003076886.1 254792049 8215519 1023200..1023676 1 NC_013008.1 oxidoreductase 1023676 ybjN 8215519 ybjN Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003076886.1 1023200 D 544404 CDS YP_003076887.1 254792050 8215520 1024027..1025139 1 NC_013008.1 putrescine ABC transporter periplasmic-binding protein 1025139 potF 8215520 potF Escherichia coli O157:H7 str. TW14359 putrescine ABC transporter periplasmic-binding protein YP_003076887.1 1024027 D 544404 CDS YP_003076888.1 254792051 8215521 1025234..1026367 1 NC_013008.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit 1026367 potG 8215521 potG Escherichia coli O157:H7 str. TW14359 putrescine transporter ATP-binding subunit YP_003076888.1 1025234 D 544404 CDS YP_003076889.1 254792052 8215522 1026377..1027330 1 NC_013008.1 putrescine ABC transporter membrane protein 1027330 potH 8215522 potH Escherichia coli O157:H7 str. TW14359 putrescine ABC transporter membrane protein YP_003076889.1 1026377 D 544404 CDS YP_003076890.1 254792053 8215523 1027327..1028172 1 NC_013008.1 putrescine ABC transporter membrane protein 1028172 potI 8215523 potI Escherichia coli O157:H7 str. TW14359 putrescine ABC transporter membrane protein YP_003076890.1 1027327 D 544404 CDS YP_003076891.1 254792054 8215524 1028232..1028720 1 NC_013008.1 inner membrane protein 1028720 ybjO 8215524 ybjO Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076891.1 1028232 D 544404 CDS YP_003076892.1 254792055 8215525 1028761..1029888 1 NC_013008.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1029888 rumB 8215525 rumB Escherichia coli O157:H7 str. TW14359 23S rRNA methyluridine methyltransferase YP_003076892.1 1028761 D 544404 CDS YP_003076893.1 254792056 8215526 1030168..1031511 1 NC_013008.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1031511 8215526 ECSP_0960 Escherichia coli O157:H7 str. TW14359 PTS system ascorbate-specific transporter subunit IIC YP_003076893.1 1030168 D 544404 CDS YP_003076894.1 254792057 8215527 1031533..1031853 1 NC_013008.1 hypothetical protein 1031853 8215527 ECSP_0961 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076894.1 1031533 D 544404 CDS YP_003076895.1 254792058 8215528 1031865..1033346 1 NC_013008.1 sulfatase 1033346 8215528 ECSP_0962 Escherichia coli O157:H7 str. TW14359 sulfatase YP_003076895.1 1031865 D 544404 CDS YP_003076896.1 254792059 8215529 complement(1033397..1034128) 1 NC_013008.1 arginine ABC transporter substrate-binding protein 1034128 artJ 8215529 artJ Escherichia coli O157:H7 str. TW14359 arginine ABC transporter substrate-binding protein YP_003076896.1 1033397 R 544404 CDS YP_003076897.1 254792060 8215530 complement(1034419..1035087) 1 NC_013008.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 1035087 artM 8215530 artM Escherichia coli O157:H7 str. TW14359 arginine transporter permease subunit ArtM YP_003076897.1 1034419 R 544404 CDS YP_003076898.1 254792061 8215531 complement(1035087..1035803) 1 NC_013008.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 1035803 artQ 8215531 artQ Escherichia coli O157:H7 str. TW14359 arginine transporter permease subunit ArtQ YP_003076898.1 1035087 R 544404 CDS YP_003076899.1 254792062 8215532 complement(1035810..1036541) 1 NC_013008.1 arginine ABC transporter substrate-binding protein 1036541 artI 8215532 artI Escherichia coli O157:H7 str. TW14359 arginine ABC transporter substrate-binding protein YP_003076899.1 1035810 R 544404 CDS YP_003076900.1 254792063 8215533 complement(1036559..1037287) 1 NC_013008.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1037287 artP 8215533 artP Escherichia coli O157:H7 str. TW14359 arginine transporter ATP-binding subunit YP_003076900.1 1036559 R 544404 CDS YP_003076901.1 254792064 8215534 complement(1037505..1038020) 1 NC_013008.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 1038020 ybjP 8215534 ybjP Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003076901.1 1037505 R 544404 CDS YP_003076902.1 254792065 8215535 complement(1038034..1038216) 1 NC_013008.1 hypothetical protein 1038216 8215535 ECSP_0969 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076902.1 1038034 R 544404 CDS YP_003076903.1 254792066 8215536 1038644..1040443 1 NC_013008.1 hypothetical protein 1040443 8215536 ECSP_0970 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076903.1 1038644 D 544404 CDS YP_003076904.1 254792067 8215537 1040654..1040977 1 NC_013008.1 hypothetical protein 1040977 ybjQ 8215537 ybjQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076904.1 1040654 D 544404 CDS YP_003076905.1 254792068 8215538 1040974..1041804 1 NC_013008.1 amidase and lipoprotein 1041804 ybjR 8215538 ybjR Escherichia coli O157:H7 str. TW14359 amidase and lipoprotein YP_003076905.1 1040974 D 544404 CDS YP_003076906.1 254792069 8215539 complement(1041801..1042814) 1 NC_013008.1 NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain 1042814 ybjS 8215539 ybjS Escherichia coli O157:H7 str. TW14359 NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain YP_003076906.1 1041801 R 544404 CDS YP_003076907.1 254792070 8215540 complement(1042913..1044343) 1 NC_013008.1 hypothetical protein 1044343 ybjT 8215540 ybjT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076907.1 1042913 R 544404 CDS YP_003076908.1 254792071 8215541 complement(1044354..1045355) 1 NC_013008.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 1045355 ltaE 8215541 ltaE Escherichia coli O157:H7 str. TW14359 L-threonine aldolase YP_003076908.1 1044354 R 544404 CDS YP_003076909.1 254792072 8215542 complement(1045392..1047110) 1 NC_013008.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 1047110 poxB 8215542 poxB Escherichia coli O157:H7 str. TW14359 pyruvate dehydrogenase YP_003076909.1 1045392 R 544404 CDS YP_003076910.1 254792073 8215543 complement(1047243..1048211) 1 NC_013008.1 HCP oxidoreductase, NADH-dependent 1048211 hcr 8215543 hcr Escherichia coli O157:H7 str. TW14359 HCP oxidoreductase, NADH-dependent YP_003076910.1 1047243 R 544404 CDS YP_003076911.1 254792074 8215544 complement(1048223..1049875) 1 NC_013008.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1049875 hcp 8215544 hcp Escherichia coli O157:H7 str. TW14359 hydroxylamine reductase YP_003076911.1 1048223 R 544404 CDS YP_003076912.1 254792075 8215545 complement(1050019..1050918) 1 NC_013008.1 transporter 1050918 ybjE 8215545 ybjE Escherichia coli O157:H7 str. TW14359 transporter YP_003076912.1 1050019 R 544404 CDS YP_003076913.1 254792076 8215546 complement(1051376..1052071) 1 NC_013008.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1052071 aqpZ 8215546 aqpZ Escherichia coli O157:H7 str. TW14359 aquaporin Z YP_003076913.1 1051376 R 544404 CDS YP_003076914.1 254792077 8215547 1052497..1054155 1 NC_013008.1 hypothetical protein 1054155 ybjD 8215547 ybjD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076914.1 1052497 D 544404 CDS YP_003076915.1 254792078 8215548 complement(1054152..1055144) 1 NC_013008.1 hypothetical protein 1055144 ybjX 8215548 ybjX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076915.1 1054152 R 544404 CDS YP_003076916.1 254792079 8215549 1055259..1056374 1 NC_013008.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1056374 macA 8215549 macA Escherichia coli O157:H7 str. TW14359 macrolide transporter subunit MacA YP_003076916.1 1055259 D 544404 CDS YP_003076917.1 254792080 8215550 1056371..1058317 1 NC_013008.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1058317 macB 8215550 macB Escherichia coli O157:H7 str. TW14359 macrolide transporter ATP-binding /permease YP_003076917.1 1056371 D 544404 CDS YP_003076918.1 254792081 8215551 complement(1058390..1058614) 1 NC_013008.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 1058614 cspD 8215551 cspD Escherichia coli O157:H7 str. TW14359 stationary phase/starvation inducible regulatory protein CspD YP_003076918.1 1058390 R 544404 CDS YP_003076919.1 254792082 8215552 1058937..1059257 1 NC_013008.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1059257 clpS 8215552 clpS Escherichia coli O157:H7 str. TW14359 ATP-dependent Clp protease adaptor protein ClpS YP_003076919.1 1058937 D 544404 CDS YP_003076920.1 254792083 8215553 1059288..1061564 1 NC_013008.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1061564 clpA 8215553 clpA Escherichia coli O157:H7 str. TW14359 ATP-dependent Clp protease ATP-binding subunit YP_003076920.1 1059288 D 544404 CDS YP_003076921.1 254792084 8215555 complement(1062251..1062469) 1 NC_013008.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1062469 infA 8215555 infA Escherichia coli O157:H7 str. TW14359 translation initiation factor IF-1 YP_003076921.1 1062251 R 544404 CDS YP_003076922.1 254792085 8215556 complement(1062754..1063458) 1 NC_013008.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1063458 aat 8215556 aat Escherichia coli O157:H7 str. TW14359 leucyl/phenylalanyl-tRNA--protein transferase YP_003076922.1 1062754 R 544404 CDS YP_003076923.1 254792086 8215557 complement(1063500..1065221) 1 NC_013008.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1065221 cydC 8215557 cydC Escherichia coli O157:H7 str. TW14359 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_003076923.1 1063500 R 544404 CDS YP_003076924.1 254792087 8215558 complement(1065222..1066988) 1 NC_013008.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1066988 cydD 8215558 cydD Escherichia coli O157:H7 str. TW14359 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_003076924.1 1065222 R 544404 CDS YP_003076925.1 254792088 8215559 complement(1067111..1068076) 1 NC_013008.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 1068076 trxB 8215559 trxB Escherichia coli O157:H7 str. TW14359 thioredoxin reductase YP_003076925.1 1067111 R 544404 CDS YP_003076926.1 254792089 8215560 1068621..1069115 1 NC_013008.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1069115 lrp 8215560 lrp Escherichia coli O157:H7 str. TW14359 leucine-responsive transcriptional regulator YP_003076926.1 1068621 D 544404 CDS YP_003076927.1 254792090 8215561 1069250..1073278 1 NC_013008.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 1073278 ftsK 8215561 ftsK Escherichia coli O157:H7 str. TW14359 DNA translocase FtsK YP_003076927.1 1069250 D 544404 CDS YP_003076928.1 254792091 8215562 1073433..1074044 1 NC_013008.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1074044 lolA 8215562 lolA Escherichia coli O157:H7 str. TW14359 outer-membrane lipoprotein carrier protein YP_003076928.1 1073433 D 544404 CDS YP_003076929.1 254792092 8215563 1074055..1075398 1 NC_013008.1 recombination factor protein RarA 1075398 ycaJ 8215563 ycaJ Escherichia coli O157:H7 str. TW14359 recombination factor protein RarA YP_003076929.1 1074055 D 544404 CDS YP_003076930.1 254792093 8215564 1075489..1076781 1 NC_013008.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1076781 serS 8215564 serS Escherichia coli O157:H7 str. TW14359 seryl-tRNA synthetase YP_003076930.1 1075489 D 544404 CDS YP_003076931.1 254792094 8215565 1077020..1079464 1 NC_013008.1 dimethyl sulfoxide reductase subunit A 1079464 dmsA 8215565 dmsA Escherichia coli O157:H7 str. TW14359 dimethyl sulfoxide reductase subunit A YP_003076931.1 1077020 D 544404 CDS YP_003076932.1 254792095 8215566 1079475..1080092 1 NC_013008.1 dimethyl sulfoxide reductase subunit B 1080092 dmsB 8215566 dmsB Escherichia coli O157:H7 str. TW14359 dimethyl sulfoxide reductase subunit B YP_003076932.1 1079475 D 544404 CDS YP_003076933.1 254792096 8215567 1080094..1080957 1 NC_013008.1 dimethyl sulfoxide reductase subunit C 1080957 dmsC 8215567 dmsC Escherichia coli O157:H7 str. TW14359 dimethyl sulfoxide reductase subunit C YP_003076933.1 1080094 D 544404 CDS YP_003076934.1 254792097 8215568 complement(1080993..1081619) 1 NC_013008.1 hydrolase 1081619 ycaC 8215568 ycaC Escherichia coli O157:H7 str. TW14359 hydrolase YP_003076934.1 1080993 R 544404 CDS YP_003076935.1 254792098 8215569 1081934..1083082 1 NC_013008.1 MFS family transporter protein 1083082 ycaD 8215569 ycaD Escherichia coli O157:H7 str. TW14359 MFS family transporter protein YP_003076935.1 1081934 D 544404 CDS YP_003076936.1 254792099 8215570 1083292..1084722 1 NC_013008.1 transporter 1084722 ycaM 8215570 ycaM Escherichia coli O157:H7 str. TW14359 transporter YP_003076936.1 1083292 D 544404 CDS YP_003076937.1 254792100 8215571 1084726..1084845 1 NC_013008.1 hypothetical protein 1084845 8215571 ECSP_1005 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076937.1 1084726 D 544404 CDS YP_003076938.1 254792101 8215572 complement(1084932..1085672) 1 NC_013008.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1085672 pflA 8215572 pflA Escherichia coli O157:H7 str. TW14359 pyruvate formate lyase-activating enzyme 1 YP_003076938.1 1084932 R 544404 CDS YP_003076939.1 254792102 8215573 complement(1085864..1088146) 1 NC_013008.1 pyruvate formate lyase I 1088146 pflB 8215573 pflB Escherichia coli O157:H7 str. TW14359 pyruvate formate lyase I YP_003076939.1 1085864 R 544404 CDS YP_003076940.1 254792103 8215574 complement(1088201..1089058) 1 NC_013008.1 formate transporter 1089058 focA 8215574 focA Escherichia coli O157:H7 str. TW14359 formate transporter YP_003076940.1 1088201 R 544404 CDS YP_003076941.1 254792104 8215575 complement(1089464..1091224) 1 NC_013008.1 hypothetical protein 1091224 ycaO 8215575 ycaO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076941.1 1089464 R 544404 CDS YP_003076942.1 254792105 8215576 1091354..1092046 1 NC_013008.1 hypothetical protein 1092046 ycaP 8215576 ycaP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076942.1 1091354 D 544404 CDS YP_003076943.1 254792106 8215577 1092245..1093333 1 NC_013008.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1093333 serC 8215577 serC Escherichia coli O157:H7 str. TW14359 phosphoserine aminotransferase YP_003076943.1 1092245 D 544404 CDS YP_003076944.1 254792107 8215578 1093404..1094687 1 NC_013008.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1094687 aroA 8215578 aroA Escherichia coli O157:H7 str. TW14359 3-phosphoshikimate 1-carboxyvinyltransferase YP_003076944.1 1093404 D 544404 CDS YP_003076945.1 254792108 8215579 1094856..1095620 1 NC_013008.1 peptidase 1095620 ycaL 8215579 ycaL Escherichia coli O157:H7 str. TW14359 peptidase YP_003076945.1 1094856 D 544404 CDS YP_003076946.1 254792109 8215580 1095793..1096476 1 NC_013008.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1096476 cmk 8215580 cmk Escherichia coli O157:H7 str. TW14359 cytidylate kinase YP_003076946.1 1095793 D 544404 CDS YP_003076947.1 254792110 8215581 1096587..1098260 1 NC_013008.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1098260 rpsA 8215581 rpsA Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S1 YP_003076947.1 1096587 D 544404 CDS YP_003076948.1 254792111 8215582 1098420..1098704 1 NC_013008.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1098704 ihfB 8215582 ihfB Escherichia coli O157:H7 str. TW14359 integration host factor subunit beta YP_003076948.1 1098420 D 544404 CDS YP_003076949.1 254792112 8215583 1098911..1101175 1 NC_013008.1 hypothetical protein 1101175 ycaI 8215583 ycaI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076949.1 1098911 D 544404 CDS YP_003076950.1 254792113 8215584 1101212..1102960 1 NC_013008.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1102960 msbA 8215584 msbA Escherichia coli O157:H7 str. TW14359 lipid transporter ATP-binding/permease YP_003076950.1 1101212 D 544404 CDS YP_003076951.1 254792114 8215585 1102957..1103943 1 NC_013008.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1103943 lpxK 8215585 lpxK Escherichia coli O157:H7 str. TW14359 tetraacyldisaccharide 4'-kinase YP_003076951.1 1102957 D 544404 CDS YP_003076952.1 254792115 8215586 1103980..1105212 1 NC_013008.1 hypothetical protein 1105212 ycaQ 8215586 ycaQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076952.1 1103980 D 544404 CDS YP_003076953.1 254792116 8215587 1105264..1105446 1 NC_013008.1 hypothetical protein 1105446 ycaR 8215587 ycaR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076953.1 1105264 D 544404 CDS YP_003076954.1 254792117 8215588 1105443..1106189 1 NC_013008.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1106189 kdsB 8215588 kdsB Escherichia coli O157:H7 str. TW14359 3-deoxy-manno-octulosonate cytidylyltransferase YP_003076954.1 1105443 D 544404 CDS YP_003076955.1 254792118 8215589 1106343..1107236 1 NC_013008.1 hypothetical protein 1107236 ycbJ 8215589 ycbJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076955.1 1106343 D 544404 CDS YP_003076956.1 254792119 8215590 complement(1107213..1107992) 1 NC_013008.1 hypothetical protein 1107992 ycbC 8215590 ycbC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076956.1 1107213 R 544404 CDS YP_003076957.1 254792120 8215591 1108128..1108913 1 NC_013008.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1108913 smtA 8215591 smtA Escherichia coli O157:H7 str. TW14359 metallothionein SmtA YP_003076957.1 1108128 D 544404 CDS YP_003076958.1 254792121 8215592 1108910..1110232 1 NC_013008.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1110232 mukF 8215592 mukF Escherichia coli O157:H7 str. TW14359 condesin subunit F YP_003076958.1 1108910 D 544404 CDS YP_003076959.1 254792122 8215593 1110213..1110917 1 NC_013008.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1110917 mukE 8215593 mukE Escherichia coli O157:H7 str. TW14359 condesin subunit E YP_003076959.1 1110213 D 544404 CDS YP_003076960.1 254792123 8215594 1110917..1115377 1 NC_013008.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1115377 mukB 8215594 mukB Escherichia coli O157:H7 str. TW14359 cell division protein MukB YP_003076960.1 1110917 D 544404 CDS YP_003076961.1 254792124 8215595 1115638..1117485 1 NC_013008.1 hypothetical protein 1117485 ycbB 8215595 ycbB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076961.1 1115638 D 544404 CDS YP_003076962.1 254792125 8215596 1117666..1118214 1 NC_013008.1 hypothetical protein 1118214 ycbK 8215596 ycbK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076962.1 1117666 D 544404 CDS YP_003076963.1 254792126 8215597 1118241..1118888 1 NC_013008.1 metal-binding enzyme 1118888 ycbL 8215597 ycbL Escherichia coli O157:H7 str. TW14359 metal-binding enzyme YP_003076963.1 1118241 D 544404 CDS YP_003076964.1 254792127 8215598 complement(1118939..1120129) 1 NC_013008.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1120129 aspC 8215598 aspC Escherichia coli O157:H7 str. TW14359 aromatic amino acid aminotransferase YP_003076964.1 1118939 R 544404 CDS YP_003076965.1 254792128 8215599 complement(1120203..1120301) 1 NC_013008.1 hypothetical protein 1120301 8215599 ECSP_1033 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076965.1 1120203 R 544404 CDS YP_003076966.1 254792129 8215600 complement(1120314..1121402) 1 NC_013008.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1121402 ompF 8215600 ompF Escherichia coli O157:H7 str. TW14359 outer membrane protein F YP_003076966.1 1120314 R 544404 CDS YP_003076967.1 254792130 8215601 complement(1122005..1123405) 1 NC_013008.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1123405 asnC 8215601 asnC Escherichia coli O157:H7 str. TW14359 asparaginyl-tRNA synthetase YP_003076967.1 1122005 R 544404 CDS YP_003076968.1 254792131 8215602 complement(1123574..1124776) 1 NC_013008.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1124776 pncB 8215602 pncB Escherichia coli O157:H7 str. TW14359 nicotinate phosphoribosyltransferase YP_003076968.1 1123574 R 544404 CDS YP_003076969.1 254792132 8215603 1125042..1127654 1 NC_013008.1 aminopeptidase 1127654 pepN 8215603 pepN Escherichia coli O157:H7 str. TW14359 aminopeptidase YP_003076969.1 1125042 D 544404 CDS YP_003076970.1 254792133 8215604 complement(1127697..1128464) 1 NC_013008.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1128464 ssuB 8215604 ssuB Escherichia coli O157:H7 str. TW14359 aliphatic sulfonates transport ATP-binding subunit YP_003076970.1 1127697 R 544404 CDS YP_003076971.1 254792134 8215605 complement(1128461..1129252) 1 NC_013008.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit 1129252 ssuC 8215605 ssuC Escherichia coli O157:H7 str. TW14359 alkanesulfonate transporter permease subunit YP_003076971.1 1128461 R 544404 CDS YP_003076972.1 254792135 8215606 complement(1129264..1130409) 1 NC_013008.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1130409 ssuD 8215606 ssuD Escherichia coli O157:H7 str. TW14359 alkanesulfonate monooxygenase YP_003076972.1 1129264 R 544404 CDS YP_003076973.1 254792136 8215607 complement(1130406..1131365) 1 NC_013008.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1131365 ssuA 8215607 ssuA Escherichia coli O157:H7 str. TW14359 alkanesulfonate transporter substrate-binding subunit YP_003076973.1 1130406 R 544404 CDS YP_003076974.1 254792137 8215608 complement(1131358..1131933) 1 NC_013008.1 NAD(P)H-dependent FMN reductase 1131933 ssuE 8215608 ssuE Escherichia coli O157:H7 str. TW14359 NAD(P)H-dependent FMN reductase YP_003076974.1 1131358 R 544404 CDS YP_003076975.1 254792138 8215609 1132289..1132828 1 NC_013008.1 fimbrial-like adhesin protein 1132828 ycbQ 8215609 ycbQ Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076975.1 1132289 D 544404 CDS YP_003076976.1 254792139 8215610 1132911..1133612 1 NC_013008.1 periplasmic pilin chaperone 1133612 ycbR 8215610 ycbR Escherichia coli O157:H7 str. TW14359 periplasmic pilin chaperone YP_003076976.1 1132911 D 544404 CDS YP_003076977.1 254792140 8215612 1136227..1137207 1 NC_013008.1 fimbrial-like adhesin protein 1137207 ycbT 8215612 ycbT Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076977.1 1136227 D 544404 CDS YP_003076978.1 254792141 8215613 1137208..1137297 1 NC_013008.1 hypothetical protein 1137297 8215613 ECSP_1047 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076978.1 1137208 D 544404 CDS YP_003076979.1 254792142 8215614 1137400..1137852 1 NC_013008.1 fimbrial-like adhesin protein 1137852 8215614 ECSP_1048 Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076979.1 1137400 D 544404 CDS YP_003076980.1 254792143 8215615 1137860..1138375 1 NC_013008.1 fimbrial-like adhesin protein 1138375 ycbV 8215615 ycbV Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003076980.1 1137860 D 544404 CDS YP_003076981.1 254792144 8215616 1138368..1138910 1 NC_013008.1 periplasmic pilin chaperone 1138910 ycbF 8215616 ycbF Escherichia coli O157:H7 str. TW14359 periplasmic pilin chaperone YP_003076981.1 1138368 D 544404 CDS YP_003076982.1 254792145 8215617 1139188..1140198 1 NC_013008.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1140198 pyrD 8215617 pyrD Escherichia coli O157:H7 str. TW14359 dihydroorotate dehydrogenase 2 YP_003076982.1 1139188 D 544404 CDS YP_003076983.1 254792146 8215618 1140372..1140914 1 NC_013008.1 hypothetical protein 1140914 ycbW 8215618 ycbW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076983.1 1140372 D 544404 CDS YP_003076984.1 254792147 8215619 complement(1140911..1142020) 1 NC_013008.1 2Fe-2S cluster-containing protein 1142020 ycbX 8215619 ycbX Escherichia coli O157:H7 str. TW14359 2Fe-2S cluster-containing protein YP_003076984.1 1140911 R 544404 CDS YP_003076985.1 254792148 8215620 1142264..1144372 1 NC_013008.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1144372 rlmL 8215620 rlmL Escherichia coli O157:H7 str. TW14359 23S rRNA m(2)G2445 methyltransferase YP_003076985.1 1142264 D 544404 CDS YP_003076986.1 254792149 8215621 1144384..1146291 1 NC_013008.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1146291 uup 8215621 uup Escherichia coli O157:H7 str. TW14359 ABC transporter ATPase YP_003076986.1 1144384 D 544404 CDS YP_003076987.1 254792150 8215622 1146421..1147674 1 NC_013008.1 paraquat-inducible membrane protein A 1147674 pqiA 8215622 pqiA Escherichia coli O157:H7 str. TW14359 paraquat-inducible membrane protein A YP_003076987.1 1146421 D 544404 CDS YP_003076988.1 254792151 8215623 1147679..1149319 1 NC_013008.1 paraquat-inducible protein B 1149319 pqiB 8215623 pqiB Escherichia coli O157:H7 str. TW14359 paraquat-inducible protein B YP_003076988.1 1147679 D 544404 CDS YP_003076989.1 254792152 8215624 1149316..1149879 1 NC_013008.1 hypothetical protein 1149879 ymbA 8215624 ymbA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076989.1 1149316 D 544404 CDS YP_003076990.1 254792153 8215625 1150119..1150316 1 NC_013008.1 ribosome modulation factor 1150316 rmf 8215625 rmf Escherichia coli O157:H7 str. TW14359 ribosome modulation factor YP_003076990.1 1150119 D 544404 CDS YP_003076991.1 254792154 8215626 complement(1150372..1150890) 1 NC_013008.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1150890 fabA 8215626 fabA Escherichia coli O157:H7 str. TW14359 3-hydroxydecanoyl-ACP dehydratase YP_003076991.1 1150372 R 544404 CDS YP_003076992.1 254792155 8215627 complement(1150959..1152719) 1 NC_013008.1 peptidase 1152719 ycbZ 8215627 ycbZ Escherichia coli O157:H7 str. TW14359 peptidase YP_003076992.1 1150959 R 544404 CDS YP_003076993.1 254792156 8215628 1152905..1153357 1 NC_013008.1 hypothetical protein 1153357 ycbG 8215628 ycbG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076993.1 1152905 D 544404 CDS YP_003076994.1 254792157 8215629 complement(1153432..1154472) 1 NC_013008.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1154472 ompA 8215629 ompA Escherichia coli O157:H7 str. TW14359 outer membrane protein A YP_003076994.1 1153432 R 544404 CDS YP_003076995.1 254792158 8215630 complement(1154829..1155338) 1 NC_013008.1 SOS cell division inhibitor 1155338 sulA 8215630 sulA Escherichia coli O157:H7 str. TW14359 SOS cell division inhibitor YP_003076995.1 1154829 R 544404 CDS YP_003076996.1 254792159 8215631 1155557..1156186 1 NC_013008.1 CRP-S promoter co-activator 1156186 sxy 8215631 sxy Escherichia coli O157:H7 str. TW14359 CRP-S promoter co-activator YP_003076996.1 1155557 D 544404 CDS YP_003076997.1 254792160 8215632 complement(1156149..1158302) 1 NC_013008.1 inner membrane protein 1158302 yccS 8215632 yccS Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003076997.1 1156149 R 544404 CDS YP_003076998.1 254792161 8215633 complement(1158321..1158767) 1 NC_013008.1 hypothetical protein 1158767 yccF 8215633 yccF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003076998.1 1158321 R 544404 CDS YP_003076999.1 254792162 8215634 1158890..1160944 1 NC_013008.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1160944 helD 8215634 helD Escherichia coli O157:H7 str. TW14359 DNA helicase IV YP_003076999.1 1158890 D 544404 CDS YP_003077000.1 254792163 8215635 complement(1160976..1161434) 1 NC_013008.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1161434 mgsA 8215635 mgsA Escherichia coli O157:H7 str. TW14359 methylglyoxal synthase YP_003077000.1 1160976 R 544404 CDS YP_003077001.1 254792164 8215636 complement(1161530..1162192) 1 NC_013008.1 hypothetical protein 1162192 yccT 8215636 yccT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077001.1 1161530 R 544404 CDS YP_003077002.1 254792165 8215637 1162365..1162778 1 NC_013008.1 CoA-binding protein with NAD(P)-binding Rossmann-fold domain 1162778 yccU 8215637 yccU Escherichia coli O157:H7 str. TW14359 CoA-binding protein with NAD(P)-binding Rossmann-fold domain YP_003077002.1 1162365 D 544404 CDS YP_003077003.1 254792166 8215638 complement(1162823..1163140) 1 NC_013008.1 heat shock protein HspQ 1163140 hspQ 8215638 hspQ Escherichia coli O157:H7 str. TW14359 heat shock protein HspQ YP_003077003.1 1162823 R 544404 CDS YP_003077004.1 254792167 8215639 complement(1163198..1164388) 1 NC_013008.1 methyltransferase 1164388 yccW 8215639 yccW Escherichia coli O157:H7 str. TW14359 methyltransferase YP_003077004.1 1163198 R 544404 CDS YP_003077005.1 254792168 8215640 1164483..1164761 1 NC_013008.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1164761 yccX 8215640 yccX Escherichia coli O157:H7 str. TW14359 acylphosphatase YP_003077005.1 1164483 D 544404 CDS YP_003077006.1 254792169 8215641 complement(1164758..1165087) 1 NC_013008.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1165087 yccK 8215641 yccK Escherichia coli O157:H7 str. TW14359 sulfur transfer protein TusE YP_003077006.1 1164758 R 544404 CDS YP_003077007.1 254792170 8215642 complement(1165178..1165837) 1 NC_013008.1 hypothetical protein 1165837 yccA 8215642 yccA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077007.1 1165178 R 544404 CDS YP_003077008.1 254792171 8215644 complement(1167229..1167471) 1 NC_013008.1 hypothetical protein 1167471 8215644 ECSP_1078 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077008.1 1167229 R 544404 CDS YP_003077009.1 254792172 8215645 complement(1167539..1170010) 1 NC_013008.1 exodeoxyribonuclease VIII for cryptic prophage CP-933M 1170010 8215645 ECSP_1079 Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease VIII for cryptic prophage CP-933M YP_003077009.1 1167539 R 544404 CDS YP_003077010.1 254792173 8215646 complement(1170104..1170295) 1 NC_013008.1 hypothetical protein 1170295 8215646 ECSP_1080 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077010.1 1170104 R 544404 CDS YP_003077011.1 254792174 8215647 complement(1170292..1170480) 1 NC_013008.1 inhibitor of cell division encoded by cryptic prophage CP-933M 1170480 8215647 ECSP_1081 Escherichia coli O157:H7 str. TW14359 inhibitor of cell division encoded by cryptic prophage CP-933M YP_003077011.1 1170292 R 544404 CDS YP_003077012.1 254792175 8215648 1171054..1171239 1 NC_013008.1 hypothetical protein 1171239 8215648 ECSP_1082 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077012.1 1171054 D 544404 CDS YP_003077013.1 254792176 8215649 complement(1171426..1171815) 1 NC_013008.1 hypothetical protein 1171815 8215649 ECSP_1083 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077013.1 1171426 R 544404 CDS YP_003077014.1 254792177 8215650 complement(1171827..1171955) 1 NC_013008.1 hypothetical protein 1171955 8215650 ECSP_1084 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077014.1 1171827 R 544404 CDS YP_003077015.1 254792178 8215651 complement(1171957..1172112) 1 NC_013008.1 hypothetical protein 1172112 8215651 ECSP_1085 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077015.1 1171957 R 544404 CDS YP_003077016.1 254792179 8215652 complement(1172390..1172677) 1 NC_013008.1 hypothetical protein 1172677 8215652 ECSP_1086 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077016.1 1172390 R 544404 CDS YP_003077017.1 254792180 8215653 complement(1172677..1172868) 1 NC_013008.1 hypothetical protein 1172868 8215653 ECSP_1087 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077017.1 1172677 R 544404 CDS YP_003077018.1 254792181 8215654 complement(1172896..1173294) 1 NC_013008.1 encoded within cryptic prophage CP-933M; DicA-like protein, regulator of DicB 1173294 8215654 ECSP_1088 Escherichia coli O157:H7 str. TW14359 DicA-like protein, regulator of DicB YP_003077018.1 1172896 R 544404 CDS YP_003077019.1 254792182 8215655 1173406..1173678 1 NC_013008.1 hypothetical protein 1173678 8215655 ECSP_1089 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077019.1 1173406 D 544404 CDS YP_003077020.1 254792183 8215656 1173662..1174087 1 NC_013008.1 hypothetical protein 1174087 8215656 ECSP_1090 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077020.1 1173662 D 544404 CDS YP_003077021.1 254792184 8215657 1174053..1174610 1 NC_013008.1 hypothetical protein 1174610 8215657 ECSP_1091 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077021.1 1174053 D 544404 CDS YP_003077022.1 254792185 8215658 1174717..1175925 1 NC_013008.1 hypothetical protein 1175925 8215658 ECSP_1092 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077022.1 1174717 D 544404 CDS YP_003077023.1 254792186 8215659 1175932..1176678 1 NC_013008.1 replication protein 1176678 8215659 ECSP_1093 Escherichia coli O157:H7 str. TW14359 replication protein YP_003077023.1 1175932 D 544404 CDS YP_003077024.1 254792187 8215660 1176700..1177470 1 NC_013008.1 hypothetical protein 1177470 8215660 ECSP_1094 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077024.1 1176700 D 544404 CDS YP_003077025.1 254792188 8215661 1177486..1177899 1 NC_013008.1 hypothetical protein 1177899 8215661 ECSP_1095 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077025.1 1177486 D 544404 CDS YP_003077026.1 254792189 8215662 complement(1178251..1179024) 1 NC_013008.1 hypothetical protein 1179024 8215662 ECSP_1096 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077026.1 1178251 R 544404 CDS YP_003077027.1 254792190 8215663 1179629..1179784 1 NC_013008.1 cell killing protein encoded within cryptic prophage CP-933M 1179784 8215663 ECSP_1097 Escherichia coli O157:H7 str. TW14359 cell killing protein encoded within cryptic prophage CP-933M YP_003077027.1 1179629 D 544404 CDS YP_003077028.1 254792191 8215664 1179952..1180230 1 NC_013008.1 hypothetical protein 1180230 8215664 ECSP_1098 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077028.1 1179952 D 544404 CDS YP_003077029.1 254792192 8215665 1180232..1181281 1 NC_013008.1 hypothetical protein 1181281 8215665 ECSP_1099 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077029.1 1180232 D 544404 CDS YP_003077030.1 254792193 8215666 1181294..1181665 1 NC_013008.1 endonuclease of cryptic prophage CP-933M 1181665 8215666 ECSP_1100 Escherichia coli O157:H7 str. TW14359 endonuclease of cryptic prophage CP-933M YP_003077030.1 1181294 D 544404 CDS YP_003077031.1 254792194 8215667 1182178..1182996 1 NC_013008.1 hypothetical protein 1182996 8215667 ECSP_1101 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077031.1 1182178 D 544404 CDS YP_003077032.1 254792195 8215668 1183283..1183522 1 NC_013008.1 hypothetical protein 1183522 8215668 ECSP_1102 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077032.1 1183283 D 544404 CDS YP_003077033.1 254792196 8215669 1183617..1184330 1 NC_013008.1 envelope protein encoded within prophage CP-933N 1184330 8215669 ECSP_1103 Escherichia coli O157:H7 str. TW14359 envelope protein encoded within prophage CP-933N YP_003077033.1 1183617 D 544404 CDS YP_003077034.1 254792197 8215672 1185098..1186948 1 NC_013008.1 hypothetical protein 1186948 8215672 ECSP_1106 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077034.1 1185098 D 544404 CDS YP_003077035.1 254792198 8215673 1187124..1187450 1 NC_013008.1 transposase 1187450 8215673 ECSP_1107 Escherichia coli O157:H7 str. TW14359 transposase YP_003077035.1 1187124 D 544404 CDS YP_003077036.1 254792199 8215674 1187447..1188337 1 NC_013008.1 transposase 1188337 8215674 ECSP_1108 Escherichia coli O157:H7 str. TW14359 transposase YP_003077036.1 1187447 D 544404 CDS YP_003077037.1 254792200 8215675 complement(1188542..1188856) 1 NC_013008.1 transcriptional regulator 1188856 8215675 ECSP_1109 Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003077037.1 1188542 R 544404 CDS YP_003077038.1 254792201 8215676 complement(1189322..1189789) 1 NC_013008.1 endopeptidase 1189789 8215676 ECSP_1110 Escherichia coli O157:H7 str. TW14359 endopeptidase YP_003077038.1 1189322 R 544404 CDS YP_003077039.1 254792202 8215677 complement(1190125..1190658) 1 NC_013008.1 phage lysozyme 1190658 8215677 ECSP_1111 Escherichia coli O157:H7 str. TW14359 phage lysozyme YP_003077039.1 1190125 R 544404 CDS YP_003077040.1 254792203 8215678 1190776..1191090 1 NC_013008.1 hypothetical protein 1191090 8215678 ECSP_1112 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077040.1 1190776 D 544404 CDS YP_003077041.1 254792204 8215679 complement(1191346..1191552) 1 NC_013008.1 hypothetical protein 1191552 8215679 ECSP_1113 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077041.1 1191346 R 544404 CDS YP_003077042.1 254792205 8215680 1191560..1191721 1 NC_013008.1 hypothetical protein 1191721 8215680 ECSP_1114 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077042.1 1191560 D 544404 CDS YP_003077043.1 254792206 8215681 1192303..1192578 1 NC_013008.1 hypothetical protein 1192578 8215681 ECSP_1115 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077043.1 1192303 D 544404 CDS YP_003077044.1 254792207 8215682 1192633..1193034 1 NC_013008.1 hypothetical protein 1193034 8215682 ECSP_1116 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077044.1 1192633 D 544404 CDS YP_003077045.1 254792208 8215683 1193031..1193378 1 NC_013008.1 transposase ISEc8 1193378 8215683 ECSP_1117 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003077045.1 1193031 D 544404 CDS YP_003077046.1 254792209 8215684 1193428..1194966 1 NC_013008.1 transposase ISEc8 1194966 8215684 ECSP_1118 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003077046.1 1193428 D 544404 CDS YP_003077047.1 254792210 8215687 1197346..1198938 1 NC_013008.1 capsid protein 1198938 8215687 ECSP_1121 Escherichia coli O157:H7 str. TW14359 capsid protein YP_003077047.1 1197346 D 544404 CDS YP_003077048.1 254792211 8215688 1198928..1200433 1 NC_013008.1 capsid assembly protein 1200433 8215688 ECSP_1122 Escherichia coli O157:H7 str. TW14359 capsid assembly protein YP_003077048.1 1198928 D 544404 CDS YP_003077049.1 254792212 8215689 1200470..1200817 1 NC_013008.1 capsid protein 1200817 8215689 ECSP_1123 Escherichia coli O157:H7 str. TW14359 capsid protein YP_003077049.1 1200470 D 544404 CDS YP_003077050.1 254792213 8215690 1200875..1201141 1 NC_013008.1 hypothetical protein 1201141 8215690 ECSP_1124 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077050.1 1200875 D 544404 CDS YP_003077051.1 254792214 8215691 1201201..1201863 1 NC_013008.1 tail fiber component 1201863 8215691 ECSP_1125 Escherichia coli O157:H7 str. TW14359 tail fiber component YP_003077051.1 1201201 D 544404 CDS YP_003077052.1 254792215 8215692 1201877..1202308 1 NC_013008.1 tail component 1202308 8215692 ECSP_1126 Escherichia coli O157:H7 str. TW14359 tail component YP_003077052.1 1201877 D 544404 CDS YP_003077053.1 254792216 8215693 1202359..1202748 1 NC_013008.1 tail component 1202748 8215693 ECSP_1127 Escherichia coli O157:H7 str. TW14359 tail component YP_003077053.1 1202359 D 544404 CDS YP_003077054.1 254792217 8215694 1202729..1205308 1 NC_013008.1 tail component 1205308 8215694 ECSP_1128 Escherichia coli O157:H7 str. TW14359 tail component YP_003077054.1 1202729 D 544404 CDS YP_003077055.1 254792218 8215695 1205305..1205634 1 NC_013008.1 minor tail protein 1205634 8215695 ECSP_1129 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077055.1 1205305 D 544404 CDS YP_003077056.1 254792219 8215696 1205634..1206332 1 NC_013008.1 tail component 1206332 8215696 ECSP_1130 Escherichia coli O157:H7 str. TW14359 tail component YP_003077056.1 1205634 D 544404 CDS YP_003077057.1 254792220 8215697 1206451..1207086 1 NC_013008.1 tail fiber component 1207086 8215697 ECSP_1131 Escherichia coli O157:H7 str. TW14359 tail fiber component YP_003077057.1 1206451 D 544404 CDS YP_003077058.1 254792221 8215698 1207083..1207664 1 NC_013008.1 tail assembly protein 1207664 8215698 ECSP_1132 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003077058.1 1207083 D 544404 CDS YP_003077059.1 254792222 8215699 complement(1207855..1208514) 1 NC_013008.1 superoxide dismutase 1208514 8215699 ECSP_1133 Escherichia coli O157:H7 str. TW14359 superoxide dismutase YP_003077059.1 1207855 R 544404 CDS YP_003077060.1 254792223 8215700 1208516..1211989 1 NC_013008.1 host specificity protein 1211989 8215700 ECSP_1134 Escherichia coli O157:H7 str. TW14359 host specificity protein YP_003077060.1 1208516 D 544404 CDS YP_003077061.1 254792224 8215701 1212057..1212656 1 NC_013008.1 Ail/Lom family protein 1212656 8215701 ECSP_1135 Escherichia coli O157:H7 str. TW14359 Ail/Lom family protein YP_003077061.1 1212057 D 544404 CDS YP_003077062.1 254792225 8215702 1212678..1214033 1 NC_013008.1 tail fiber protein 1214033 8215702 ECSP_1136 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003077062.1 1212678 D 544404 CDS YP_003077063.1 254792226 8215703 1213915..1214304 1 NC_013008.1 hypothetical protein 1214304 8215703 ECSP_1137 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077063.1 1213915 D 544404 CDS YP_003077064.1 254792227 8215704 complement(1214429..1215181) 1 NC_013008.1 tir-cytoskeleton coupling protein 1215181 8215704 ECSP_1138 Escherichia coli O157:H7 str. TW14359 tir-cytoskeleton coupling protein YP_003077064.1 1214429 R 544404 CDS YP_003077065.1 254792228 8215706 1216578..1217696 1 NC_013008.1 hydrogenase 1, small subunit 1217696 hyaA 8215706 hyaA Escherichia coli O157:H7 str. TW14359 hydrogenase 1, small subunit YP_003077065.1 1216578 D 544404 CDS YP_003077066.1 254792229 8215707 1217693..1219486 1 NC_013008.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1219486 hyaB 8215707 hyaB Escherichia coli O157:H7 str. TW14359 hydrogenase 1 large subunit YP_003077066.1 1217693 D 544404 CDS YP_003077067.1 254792230 8215708 1219505..1220212 1 NC_013008.1 hydrogenase 1 b-type cytochrome subunit 1220212 hyaC 8215708 hyaC Escherichia coli O157:H7 str. TW14359 hydrogenase 1 b-type cytochrome subunit YP_003077067.1 1219505 D 544404 CDS YP_003077068.1 254792231 8215709 1220209..1220796 1 NC_013008.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1220796 hyaD 8215709 hyaD Escherichia coli O157:H7 str. TW14359 hydrogenase 1 maturation protease YP_003077068.1 1220209 D 544404 CDS YP_003077069.1 254792232 8215710 1220793..1221191 1 NC_013008.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1221191 hyaE 8215710 hyaE Escherichia coli O157:H7 str. TW14359 hydrogenase-1 operon protein HyaE YP_003077069.1 1220793 D 544404 CDS YP_003077070.1 254792233 8215711 1221188..1222045 1 NC_013008.1 protein involved in nickel incorporation into hydrogenase-1 proteins 1222045 hyaF 8215711 hyaF Escherichia coli O157:H7 str. TW14359 protein involved in nickel incorporation into hydrogenase-1 proteins YP_003077070.1 1221188 D 544404 CDS YP_003077071.1 254792234 8215712 1222179..1223723 1 NC_013008.1 cytochrome bd-II oxidase subunit I 1223723 appC 8215712 appC Escherichia coli O157:H7 str. TW14359 cytochrome bd-II oxidase subunit I YP_003077071.1 1222179 D 544404 CDS YP_003077072.1 254792235 8215713 1223735..1224871 1 NC_013008.1 cytochrome bd-II oxidase subunit II 1224871 appB 8215713 appB Escherichia coli O157:H7 str. TW14359 cytochrome bd-II oxidase subunit II YP_003077072.1 1223735 D 544404 CDS YP_003077073.1 254792236 8215714 1224884..1224976 1 NC_013008.1 expressed during stationary phase; membrane protein 1224976 8215714 ECSP_1148 Escherichia coli O157:H7 str. TW14359 membrane protein YP_003077073.1 1224884 D 544404 CDS YP_003077074.1 254792237 8215715 1225056..1226360 1 NC_013008.1 phosphoanhydride phosphorylase 1226360 appA 8215715 appA Escherichia coli O157:H7 str. TW14359 phosphoanhydride phosphorylase YP_003077074.1 1225056 D 544404 CDS YP_003077075.1 254792238 8215716 complement(1226480..1228660) 1 NC_013008.1 cryptic autophosphorylating protein tyrosine kinase Etk 1228660 etk 8215716 etk Escherichia coli O157:H7 str. TW14359 cryptic autophosphorylating protein tyrosine kinase Etk YP_003077075.1 1226480 R 544404 CDS YP_003077076.1 254792239 8215717 complement(1228680..1229126) 1 NC_013008.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 1229126 etp 8215717 etp Escherichia coli O157:H7 str. TW14359 phosphotyrosine-protein phosphatase YP_003077076.1 1228680 R 544404 CDS YP_003077077.1 254792240 8215718 complement(1229114..1230253) 1 NC_013008.1 exopolysaccharide export protein 1230253 yccZ 8215718 yccZ Escherichia coli O157:H7 str. TW14359 exopolysaccharide export protein YP_003077077.1 1229114 R 544404 CDS YP_003077078.1 254792241 8215719 complement(1230299..1232395) 1 NC_013008.1 hypothetical protein 1232395 ymcA 8215719 ymcA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077078.1 1230299 R 544404 CDS YP_003077079.1 254792242 8215720 complement(1232395..1233141) 1 NC_013008.1 hypothetical protein 1233141 ymcB 8215720 ymcB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077079.1 1232395 R 544404 CDS YP_003077080.1 254792243 8215721 complement(1233138..1233782) 1 NC_013008.1 outer membrane lipoprotein 1233782 ymcC 8215721 ymcC Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003077080.1 1233138 R 544404 CDS YP_003077081.1 254792244 8215722 complement(1233889..1234194) 1 NC_013008.1 hypothetical protein 1234194 ymcD 8215722 ymcD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077081.1 1233889 R 544404 CDS YP_003077082.1 254792245 8215723 complement(1234636..1234848) 1 NC_013008.1 stress protein, member of the CspA-family 1234848 cspH 8215723 cspH Escherichia coli O157:H7 str. TW14359 stress protein, member of the CspA-family YP_003077082.1 1234636 R 544404 CDS YP_003077083.1 254792246 8215724 complement(1234858..1234956) 1 NC_013008.1 hypothetical protein 1234956 8215724 ECSP_1158 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077083.1 1234858 R 544404 CDS YP_003077084.1 254792247 8215725 1235134..1235346 1 NC_013008.1 cold shock protein CspG 1235346 cspG 8215725 cspG Escherichia coli O157:H7 str. TW14359 cold shock protein CspG YP_003077084.1 1235134 D 544404 CDS YP_003077085.1 254792248 8215726 1235520..1235750 1 NC_013008.1 cold shock gene 1235750 ymcE 8215726 ymcE Escherichia coli O157:H7 str. TW14359 cold shock gene YP_003077085.1 1235520 D 544404 CDS YP_003077086.1 254792249 8215727 complement(1235961..1237034) 1 NC_013008.1 4Fe-4S membrane protein 1237034 yccM 8215727 yccM Escherichia coli O157:H7 str. TW14359 4Fe-4S membrane protein YP_003077086.1 1235961 R 544404 CDS YP_003077087.1 254792250 8215728 complement(1237106..1239850) 1 NC_013008.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1239850 torS 8215728 torS Escherichia coli O157:H7 str. TW14359 hybrid sensory histidine kinase TorS YP_003077087.1 1237106 R 544404 CDS YP_003077088.1 254792251 8215729 1239933..1240961 1 NC_013008.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1240961 torT 8215729 torT Escherichia coli O157:H7 str. TW14359 TMAO reductase system periplasmic protein TorT YP_003077088.1 1239933 D 544404 CDS YP_003077089.1 254792252 8215730 complement(1240934..1241626) 1 NC_013008.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1241626 torR 8215730 torR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator TorR YP_003077089.1 1240934 R 544404 CDS YP_003077090.1 254792253 8215731 1241756..1242928 1 NC_013008.1 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1242928 torC 8215731 torC Escherichia coli O157:H7 str. TW14359 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit YP_003077090.1 1241756 D 544404 CDS YP_003077091.1 254792254 8215732 1242928..1245474 1 NC_013008.1 trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1245474 torA 8215732 torA Escherichia coli O157:H7 str. TW14359 trimethylamine N-oxide (TMAO) reductase I, catalytic subunit YP_003077091.1 1242928 D 544404 CDS YP_003077092.1 254792255 8215733 1245471..1246070 1 NC_013008.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1246070 torD 8215733 torD Escherichia coli O157:H7 str. TW14359 chaperone protein TorD YP_003077092.1 1245471 D 544404 CDS YP_003077093.1 254792256 8215734 complement(1246224..1246529) 1 NC_013008.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1246529 cbpM 8215734 cbpM Escherichia coli O157:H7 str. TW14359 chaperone-modulator protein CbpM YP_003077093.1 1246224 R 544404 CDS YP_003077094.1 254792257 8215735 complement(1246529..1247449) 1 NC_013008.1 functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1247449 cbpA 8215735 cbpA Escherichia coli O157:H7 str. TW14359 curved DNA-binding protein CbpA YP_003077094.1 1246529 R 544404 CDS YP_003077095.1 254792258 8215737 1249120..1249236 1 NC_013008.1 hypothetical protein 1249236 8215737 ECSP_1171 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077095.1 1249120 D 544404 CDS YP_003077096.1 254792259 8215738 1249257..1250498 1 NC_013008.1 glucose-1-phosphatase/inositol phosphatase 1250498 agp 8215738 agp Escherichia coli O157:H7 str. TW14359 glucose-1-phosphatase/inositol phosphatase YP_003077096.1 1249257 D 544404 CDS YP_003077097.1 254792260 8215739 complement(1250536..1250763) 1 NC_013008.1 hypothetical protein 1250763 yccJ 8215739 yccJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077097.1 1250536 R 544404 CDS YP_003077098.1 254792261 8215740 complement(1250784..1251329) 1 NC_013008.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1251329 wrbA 8215740 wrbA Escherichia coli O157:H7 str. TW14359 TrpR binding protein WrbA YP_003077098.1 1250784 R 544404 CDS YP_003077099.1 254792262 8215741 complement(1251942..1253270) 1 NC_013008.1 transport protein 1253270 ycdG 8215741 ycdG Escherichia coli O157:H7 str. TW14359 transport protein YP_003077099.1 1251942 R 544404 CDS YP_003077100.1 254792263 8215742 complement(1253291..1253785) 1 NC_013008.1 oxidoreductase 1253785 8215742 ECSP_1176 Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077100.1 1253291 R 544404 CDS YP_003077101.1 254792264 8215743 complement(1253796..1254386) 1 NC_013008.1 hypothetical protein 1254386 8215743 ECSP_1177 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077101.1 1253796 R 544404 CDS YP_003077102.1 254792265 8215744 complement(1254396..1255196) 1 NC_013008.1 hydrolase 1255196 8215744 ECSP_1178 Escherichia coli O157:H7 str. TW14359 hydrolase YP_003077102.1 1254396 R 544404 CDS YP_003077103.1 254792266 8215745 complement(1255247..1255543) 1 NC_013008.1 hypothetical protein 1255543 8215745 ECSP_1179 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077103.1 1255247 R 544404 CDS YP_003077104.1 254792267 8215746 complement(1255555..1256247) 1 NC_013008.1 synthetase 1256247 8215746 ECSP_1180 Escherichia coli O157:H7 str. TW14359 synthetase YP_003077104.1 1255555 R 544404 CDS YP_003077105.1 254792268 8215747 complement(1256247..1257395) 1 NC_013008.1 monooxygenase 1257395 8215747 ECSP_1181 Escherichia coli O157:H7 str. TW14359 monooxygenase YP_003077105.1 1256247 R 544404 CDS YP_003077106.1 254792269 8215748 1257626..1258264 1 NC_013008.1 tet operon regulator 1258264 ycdC 8215748 ycdC Escherichia coli O157:H7 str. TW14359 tet operon regulator YP_003077106.1 1257626 D 544404 CDS YP_003077107.1 254792270 8215749 complement(1258304..1262266) 1 NC_013008.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1262266 putA 8215749 putA Escherichia coli O157:H7 str. TW14359 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_003077107.1 1258304 R 544404 CDS YP_003077108.1 254792271 8215750 1262689..1264197 1 NC_013008.1 proline:sodium symporter 1264197 putP 8215750 putP Escherichia coli O157:H7 str. TW14359 proline:sodium symporter YP_003077108.1 1262689 D 544404 CDS YP_003077109.1 254792272 8215751 complement(1264346..1265689) 1 NC_013008.1 hypothetical protein 1265689 8215751 ECSP_1185 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077109.1 1264346 R 544404 CDS YP_003077110.1 254792273 8215752 1266252..1266398 1 NC_013008.1 hypothetical protein 1266398 8215752 ECSP_1186 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077110.1 1266252 D 544404 CDS YP_003077111.1 254792274 8215753 complement(1266689..1266835) 1 NC_013008.1 hypothetical protein 1266835 8215753 ECSP_1187 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077111.1 1266689 R 544404 CDS YP_003077112.1 254792275 8215754 1266871..1267701 1 NC_013008.1 ferrous iron permease 1267701 efeU 8215754 efeU Escherichia coli O157:H7 str. TW14359 ferrous iron permease YP_003077112.1 1266871 D 544404 CDS YP_003077113.1 254792276 8215755 1267759..1268886 1 NC_013008.1 hypothetical protein 1268886 efeO 8215755 efeO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077113.1 1267759 D 544404 CDS YP_003077114.1 254792277 8215756 1268892..1270163 1 NC_013008.1 redox component of a tripartite ferrous iron transporter 1270163 efeB 8215756 efeB Escherichia coli O157:H7 str. TW14359 redox component of a tripartite ferrous iron transporter YP_003077114.1 1268892 D 544404 CDS YP_003077115.1 254792278 8215757 1270507..1271571 1 NC_013008.1 hypothetical protein 1271571 phoH 8215757 phoH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077115.1 1270507 D 544404 CDS YP_003077116.1 254792279 8215758 complement(1271621..1272034) 1 NC_013008.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1272034 pgaD 8215758 pgaD Escherichia coli O157:H7 str. TW14359 PGA biosynthesis protein YP_003077116.1 1271621 R 544404 CDS YP_003077117.1 254792280 8215759 complement(1272036..1273361) 1 NC_013008.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1273361 pgaC 8215759 pgaC Escherichia coli O157:H7 str. TW14359 N-glycosyltransferase YP_003077117.1 1272036 R 544404 CDS YP_003077118.1 254792281 8215760 complement(1273354..1275372) 1 NC_013008.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1275372 pgaB 8215760 pgaB Escherichia coli O157:H7 str. TW14359 outer membrane N-deacetylase YP_003077118.1 1273354 R 544404 CDS YP_003077119.1 254792282 8215761 complement(1275381..1277804) 1 NC_013008.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1277804 pgaA 8215761 pgaA Escherichia coli O157:H7 str. TW14359 outer membrane protein PgaA YP_003077119.1 1275381 R 544404 CDS YP_003077120.1 254792283 8215762 1278391..1279749 1 NC_013008.1 diguanylate cyclase 1279749 ycdT 8215762 ycdT Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003077120.1 1278391 D 544404 CDS YP_003077121.1 254792284 8215763 1279847..1281457 1 NC_013008.1 hypothetical protein 1281457 8215763 ECSP_1197 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077121.1 1279847 D 544404 CDS YP_003077122.1 254792285 8215764 complement(1281559..1282050) 1 NC_013008.1 hypothetical protein 1282050 8215764 ECSP_1198 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077122.1 1281559 R 544404 CDS YP_003077123.1 254792286 8215765 complement(1282055..1282867) 1 NC_013008.1 hypothetical protein 1282867 8215765 ECSP_1199 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077123.1 1282055 R 544404 CDS YP_003077124.1 254792287 8215766 1283546..1284337 1 NC_013008.1 oxidoreductase 1284337 8215766 ECSP_1200 Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077124.1 1283546 D 544404 CDS YP_003077125.1 254792288 8215767 complement(1284483..1285172) 1 NC_013008.1 chaperone 1285172 8215767 ECSP_1201 Escherichia coli O157:H7 str. TW14359 chaperone YP_003077125.1 1284483 R 544404 CDS YP_003077126.1 254792289 8215768 complement(1285169..1286503) 1 NC_013008.1 fimbrial-like adhesion protein 1286503 8215768 ECSP_1202 Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesion protein YP_003077126.1 1285169 R 544404 CDS YP_003077127.1 254792290 8215769 complement(1287381..1289036) 1 NC_013008.1 usher protein 1289036 8215769 ECSP_1203 Escherichia coli O157:H7 str. TW14359 usher protein YP_003077127.1 1287381 R 544404 CDS YP_003077128.1 254792291 8215770 complement(1289089..1289790) 1 NC_013008.1 chaperone 1289790 8215770 ECSP_1204 Escherichia coli O157:H7 str. TW14359 chaperone YP_003077128.1 1289089 R 544404 CDS YP_003077129.1 254792292 8215771 complement(1289876..1290436) 1 NC_013008.1 pilin subunit 1290436 8215771 ECSP_1205 Escherichia coli O157:H7 str. TW14359 pilin subunit YP_003077129.1 1289876 R 544404 CDS YP_003077130.1 254792293 8215772 complement(1290479..1291102) 1 NC_013008.1 hypothetical protein 1291102 8215772 ECSP_1206 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077130.1 1290479 R 544404 CDS YP_003077131.1 254792294 8215773 1291444..1291590 1 NC_013008.1 hypothetical protein 1291590 8215773 ECSP_1207 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077131.1 1291444 D 544404 CDS YP_003077132.1 254792295 8215774 1292284..1292436 1 NC_013008.1 hypothetical protein 1292436 8215774 ECSP_1208 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077132.1 1292284 D 544404 CDS YP_003077133.1 254792296 8215775 1292493..1296305 1 NC_013008.1 member of ShlA/HecA/FhaA exoprotein family 1296305 8215775 ECSP_1209 Escherichia coli O157:H7 str. TW14359 member of ShlA/HecA/FhaA exoprotein family YP_003077133.1 1292493 D 544404 CDS YP_003077134.1 254792297 8215776 1296394..1298013 1 NC_013008.1 outer membrane transporter of ShlA/HecA/FhaA exoprotein family 1298013 8215776 ECSP_1210 Escherichia coli O157:H7 str. TW14359 outer membrane transporter of ShlA/HecA/FhaA exoprotein family YP_003077134.1 1296394 D 544404 CDS YP_003077135.1 254792298 8215777 1298029..1298397 1 NC_013008.1 acyl carrier protein 1298397 8215777 ECSP_1211 Escherichia coli O157:H7 str. TW14359 acyl carrier protein YP_003077135.1 1298029 D 544404 CDS YP_003077136.1 254792299 8215778 1298417..1299172 1 NC_013008.1 fatty acyl chain reductase 1299172 8215778 ECSP_1212 Escherichia coli O157:H7 str. TW14359 fatty acyl chain reductase YP_003077136.1 1298417 D 544404 CDS YP_003077137.1 254792300 8215779 1299176..1299724 1 NC_013008.1 fatty acyl chain dehydrase 1299724 8215779 ECSP_1213 Escherichia coli O157:H7 str. TW14359 fatty acyl chain dehydrase YP_003077137.1 1299176 D 544404 CDS YP_003077138.1 254792301 8215780 1299746..1300027 1 NC_013008.1 acyl carrier protein 1300027 8215780 ECSP_1214 Escherichia coli O157:H7 str. TW14359 acyl carrier protein YP_003077138.1 1299746 D 544404 CDS YP_003077139.1 254792302 8215781 1300063..1301223 1 NC_013008.1 aminomethyltransferase 1301223 8215781 ECSP_1215 Escherichia coli O157:H7 str. TW14359 aminomethyltransferase YP_003077139.1 1300063 D 544404 CDS YP_003077140.1 254792303 8215782 1301297..1303855 1 NC_013008.1 beta-ketoacyl-[acyl carrier protein] synthase 1303855 8215782 ECSP_1216 Escherichia coli O157:H7 str. TW14359 beta-ketoacyl-[acyl carrier protein] synthase YP_003077140.1 1301297 D 544404 CDS YP_003077141.1 254792304 8215783 1303860..1305083 1 NC_013008.1 hypothetical protein 1305083 8215783 ECSP_1217 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077141.1 1303860 D 544404 CDS YP_003077142.1 254792305 8215784 1305080..1306033 1 NC_013008.1 hypothetical protein 1306033 8215784 ECSP_1218 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077142.1 1305080 D 544404 CDS YP_003077143.1 254792306 8215785 1306044..1306751 1 NC_013008.1 hypothetical protein 1306751 8215785 ECSP_1219 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077143.1 1306044 D 544404 CDS YP_003077144.1 254792307 8215786 1306735..1307391 1 NC_013008.1 hypothetical protein 1307391 8215786 ECSP_1220 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077144.1 1306735 D 544404 CDS YP_003077145.1 254792308 8215787 1307392..1308702 1 NC_013008.1 hypothetical protein 1308702 8215787 ECSP_1221 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077145.1 1307392 D 544404 CDS YP_003077146.1 254792309 8215788 1308711..1309499 1 NC_013008.1 hypothetical protein 1309499 8215788 ECSP_1222 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077146.1 1308711 D 544404 CDS YP_003077147.1 254792310 8215789 1309496..1310884 1 NC_013008.1 hypothetical protein 1310884 8215789 ECSP_1223 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077147.1 1309496 D 544404 CDS YP_003077148.1 254792311 8215790 1310895..1311839 1 NC_013008.1 acyl transferase 1311839 ymdE 8215790 ymdE Escherichia coli O157:H7 str. TW14359 acyl transferase YP_003077148.1 1310895 D 544404 CDS YP_003077149.1 254792312 8215791 1311836..1312822 1 NC_013008.1 inner membrane protein 1312822 ycdU 8215791 ycdU Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077149.1 1311836 D 544404 CDS YP_003077150.1 254792313 8215792 1313189..1314391 1 NC_013008.1 P4-family integrase 1314391 8215792 ECSP_1226 Escherichia coli O157:H7 str. TW14359 P4-family integrase YP_003077150.1 1313189 D 544404 CDS YP_003077151.1 254792314 8215793 complement(1314578..1316395) 1 NC_013008.1 hypothetical protein 1316395 8215793 ECSP_1227 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077151.1 1314578 R 544404 CDS YP_003077152.1 254792315 8215795 1316891..1317328 1 NC_013008.1 hypothetical protein 1317328 8215795 ECSP_1229 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077152.1 1316891 D 544404 CDS YP_003077153.1 254792316 8215796 1317507..1317803 1 NC_013008.1 prophage regulatory protein 1317803 8215796 ECSP_1230 Escherichia coli O157:H7 str. TW14359 prophage regulatory protein YP_003077153.1 1317507 D 544404 CDS YP_003077154.1 254792317 8215797 1318030..1318227 1 NC_013008.1 hypothetical protein 1318227 8215797 ECSP_1231 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077154.1 1318030 D 544404 CDS YP_003077155.1 254792318 8215798 1318446..1319831 1 NC_013008.1 hypothetical protein 1319831 8215798 ECSP_1232 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077155.1 1318446 D 544404 CDS YP_003077156.1 254792319 8215799 complement(1320727..1321614) 1 NC_013008.1 transposase 1321614 8215799 ECSP_1233 Escherichia coli O157:H7 str. TW14359 transposase YP_003077156.1 1320727 R 544404 CDS YP_003077157.1 254792320 8215800 complement(1321614..1321940) 1 NC_013008.1 transposase 1321940 8215800 ECSP_1234 Escherichia coli O157:H7 str. TW14359 transposase YP_003077157.1 1321614 R 544404 CDS YP_003077158.1 254792321 8215801 1322001..1322528 1 NC_013008.1 hypothetical protein 1322528 8215801 ECSP_1235 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077158.1 1322001 D 544404 CDS YP_003077159.1 254792322 8215802 1322683..1325043 1 NC_013008.1 helicase 1325043 8215802 ECSP_1236 Escherichia coli O157:H7 str. TW14359 helicase YP_003077159.1 1322683 D 544404 CDS YP_003077160.1 254792323 8215803 complement(1325205..1325474) 1 NC_013008.1 hypothetical protein 1325474 8215803 ECSP_1237 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077160.1 1325205 R 544404 CDS YP_003077161.1 254792324 8215804 complement(1325800..1327338) 1 NC_013008.1 transposase ISEc8 1327338 8215804 ECSP_1238 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003077161.1 1325800 R 544404 CDS YP_003077162.1 254792325 8215805 complement(1327388..1327735) 1 NC_013008.1 transposase ISEc8 1327735 8215805 ECSP_1239 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003077162.1 1327388 R 544404 CDS YP_003077163.1 254792326 8215806 complement(1327732..1328133) 1 NC_013008.1 hypothetical protein 1328133 8215806 ECSP_1240 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077163.1 1327732 R 544404 CDS YP_003077164.1 254792327 8215807 complement(1328188..1328499) 1 NC_013008.1 transposase 1328499 8215807 ECSP_1241 Escherichia coli O157:H7 str. TW14359 transposase YP_003077164.1 1328188 R 544404 CDS YP_003077165.1 254792328 8215808 1328639..1329457 1 NC_013008.1 transposase ISSd1 1329457 8215808 ECSP_1242 Escherichia coli O157:H7 str. TW14359 transposase ISSd1 YP_003077165.1 1328639 D 544404 CDS YP_003077166.1 254792329 8215809 1329570..1330109 1 NC_013008.1 complement resistance protein 1330109 8215809 ECSP_1243 Escherichia coli O157:H7 str. TW14359 complement resistance protein YP_003077166.1 1329570 D 544404 CDS YP_003077167.1 254792330 8215811 1331408..1331767 1 NC_013008.1 diacylglycerol kinase 1331767 8215811 ECSP_1245 Escherichia coli O157:H7 str. TW14359 diacylglycerol kinase YP_003077167.1 1331408 D 544404 CDS YP_003077168.1 254792331 8215812 complement(1331860..1333479) 1 NC_013008.1 hypothetical protein 1333479 8215812 ECSP_1246 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077168.1 1331860 R 544404 CDS YP_003077169.1 254792332 8215813 complement(1333704..1333979) 1 NC_013008.1 hypothetical protein 1333979 8215813 ECSP_1247 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077169.1 1333704 R 544404 CDS YP_003077170.1 254792333 8215814 1334315..1335058 1 NC_013008.1 urease accessory protein 1335058 ureD 8215814 ureD Escherichia coli O157:H7 str. TW14359 urease accessory protein YP_003077170.1 1334315 D 544404 CDS YP_003077171.1 254792334 8215815 1335149..1335451 1 NC_013008.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1335451 ureA 8215815 ureA Escherichia coli O157:H7 str. TW14359 urease subunit gamma YP_003077171.1 1335149 D 544404 CDS YP_003077172.1 254792335 8215816 1335460..1335780 1 NC_013008.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 1335780 ureB 8215816 ureB Escherichia coli O157:H7 str. TW14359 urease subunit beta YP_003077172.1 1335460 D 544404 CDS YP_003077173.1 254792336 8215817 1335770..1337476 1 NC_013008.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1337476 ureC 8215817 ureC Escherichia coli O157:H7 str. TW14359 urease subunit alpha YP_003077173.1 1335770 D 544404 CDS YP_003077174.1 254792337 8215818 1337486..1337950 1 NC_013008.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1337950 ureE 8215818 ureE Escherichia coli O157:H7 str. TW14359 urease accessory protein UreE YP_003077174.1 1337486 D 544404 CDS YP_003077175.1 254792338 8215819 1337951..1338625 1 NC_013008.1 urease accessory protein F 1338625 ureF 8215819 ureF Escherichia coli O157:H7 str. TW14359 urease accessory protein F YP_003077175.1 1337951 D 544404 CDS YP_003077176.1 254792339 8215820 1338637..1339254 1 NC_013008.1 GTP hydrolase 1339254 ureG 8215820 ureG Escherichia coli O157:H7 str. TW14359 GTP hydrolase YP_003077176.1 1338637 D 544404 CDS YP_003077177.1 254792340 8215821 complement(1339302..1339433) 1 NC_013008.1 hypothetical protein 1339433 8215821 ECSP_1255 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077177.1 1339302 R 544404 CDS YP_003077178.1 254792341 8215822 complement(1339510..1339851) 1 NC_013008.1 hypothetical protein 1339851 8215822 ECSP_1256 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077178.1 1339510 R 544404 CDS YP_003077179.1 254792342 8215823 complement(1339913..1340041) 1 NC_013008.1 hypothetical protein 1340041 8215823 ECSP_1257 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077179.1 1339913 R 544404 CDS YP_003077180.1 254792343 8215824 1340466..1340729 1 NC_013008.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1340729 rpmE2 8215824 rpmE2 Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L31 YP_003077180.1 1340466 D 544404 CDS YP_003077181.1 254792344 8215825 complement(1340683..1341039) 1 NC_013008.1 hypothetical protein 1341039 8215825 ECSP_1259 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077181.1 1340683 R 544404 CDS YP_003077182.1 254792345 8215826 1341031..1341171 1 NC_013008.1 hypothetical protein 1341171 8215826 ECSP_1260 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077182.1 1341031 D 544404 CDS YP_003077183.1 254792346 8215827 complement(1341656..1342075) 1 NC_013008.1 colicin immunity protein 1342075 8215827 ECSP_1261 Escherichia coli O157:H7 str. TW14359 colicin immunity protein YP_003077183.1 1341656 R 544404 CDS YP_003077184.1 254792347 8215828 complement(1342042..1342713) 1 NC_013008.1 hypothetical protein 1342713 8215828 ECSP_1262 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077184.1 1342042 R 544404 CDS YP_003077185.1 254792348 8215829 1343118..1343252 1 NC_013008.1 hypothetical protein 1343252 8215829 ECSP_1263 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077185.1 1343118 D 544404 CDS YP_003077186.1 254792349 8215830 complement(1343733..1343906) 1 NC_013008.1 hypothetical protein 1343906 8215830 ECSP_1264 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077186.1 1343733 R 544404 CDS YP_003077187.1 254792350 8215831 complement(1344246..1344863) 1 NC_013008.1 transposase 1344863 8215831 ECSP_1265 Escherichia coli O157:H7 str. TW14359 transposase YP_003077187.1 1344246 R 544404 CDS YP_003077188.1 254792351 8215832 1345051..1345476 1 NC_013008.1 hypothetical protein 1345476 8215832 ECSP_1266 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077188.1 1345051 D 544404 CDS YP_003077189.1 254792352 8215833 1345473..1345823 1 NC_013008.1 hypothetical protein 1345823 8215833 ECSP_1267 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077189.1 1345473 D 544404 CDS YP_003077190.1 254792353 8215834 1345854..1347467 1 NC_013008.1 hypothetical protein 1347467 8215834 ECSP_1268 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077190.1 1345854 D 544404 CDS YP_003077191.1 254792354 8215835 complement(1347471..1348328) 1 NC_013008.1 transposase, IS66 type 1348328 8215835 ECSP_1269 Escherichia coli O157:H7 str. TW14359 transposase, IS66 type YP_003077191.1 1347471 R 544404 CDS YP_003077192.1 254792355 8215836 complement(1348410..1348772) 1 NC_013008.1 transposase, ISEc8 type 1348772 8215836 ECSP_1270 Escherichia coli O157:H7 str. TW14359 transposase, ISEc8 type YP_003077192.1 1348410 R 544404 CDS YP_003077193.1 254792356 8215837 complement(1348738..1349067) 1 NC_013008.1 hypothetical protein 1349067 8215837 ECSP_1271 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077193.1 1348738 R 544404 CDS YP_003077194.1 254792357 8215838 complement(1349328..1349795) 1 NC_013008.1 hypothetical protein 1349795 terW 8215838 terW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077194.1 1349328 R 544404 CDS YP_003077195.1 254792358 8215839 complement(1349813..1351021) 1 NC_013008.1 hypothetical protein 1351021 8215839 ECSP_1273 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077195.1 1349813 R 544404 CDS YP_003077196.1 254792359 8215840 complement(1351032..1353104) 1 NC_013008.1 hypothetical protein 1353104 8215840 ECSP_1274 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077196.1 1351032 R 544404 CDS YP_003077197.1 254792360 8215841 complement(1353070..1353843) 1 NC_013008.1 hypothetical protein 1353843 8215841 ECSP_1275 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077197.1 1353070 R 544404 CDS YP_003077198.1 254792361 8215842 complement(1353836..1354978) 1 NC_013008.1 hypothetical protein 1354978 8215842 ECSP_1276 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077198.1 1353836 R 544404 CDS YP_003077199.1 254792362 8215843 complement(1354988..1356046) 1 NC_013008.1 hypothetical protein 1356046 8215843 ECSP_1277 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077199.1 1354988 R 544404 CDS YP_003077200.1 254792363 8215844 1356369..1356950 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1356950 8215844 ECSP_1278 Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077200.1 1356369 D 544404 CDS YP_003077201.1 254792364 8215845 1356950..1358107 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1358107 terA 8215845 terA Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077201.1 1356950 D 544404 CDS YP_003077202.1 254792365 8215846 1358130..1358585 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1358585 terB 8215846 terB Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077202.1 1358130 D 544404 CDS YP_003077203.1 254792366 8215847 1358608..1359648 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1359648 terC 8215847 terC Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077203.1 1358608 D 544404 CDS YP_003077204.1 254792367 8215848 1359697..1360275 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1360275 terD 8215848 terD Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077204.1 1359697 D 544404 CDS YP_003077205.1 254792368 8215849 1360344..1360919 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1360919 terE 8215849 terE Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077205.1 1360344 D 544404 CDS YP_003077206.1 254792369 8215850 1361342..1361728 1 NC_013008.1 phage inhibition, colicin resistance and tellurite resistance protein 1361728 terF 8215850 terF Escherichia coli O157:H7 str. TW14359 phage inhibition, colicin resistance and tellurite resistance protein YP_003077206.1 1361342 D 544404 CDS YP_003077207.1 254792370 8215851 complement(1362242..1364332) 1 NC_013008.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein 1364332 iha 8215851 iha Escherichia coli O157:H7 str. TW14359 bifunctional enterobactin receptor/adhesin protein YP_003077207.1 1362242 R 544404 CDS YP_003077208.1 254792371 8215852 1364271..1364453 1 NC_013008.1 hypothetical protein 1364453 8215852 ECSP_1286 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077208.1 1364271 D 544404 CDS YP_003077209.1 254792372 8215854 1366636..1366971 1 NC_013008.1 hypothetical protein 1366971 8215854 ECSP_1288 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077209.1 1366636 D 544404 CDS YP_003077210.1 254792373 8215855 1367488..1367622 1 NC_013008.1 hypothetical protein 1367622 8215855 ECSP_1289 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077210.1 1367488 D 544404 CDS YP_003077211.1 254792374 8215856 complement(1367752..1367946) 1 NC_013008.1 hypothetical protein 1367946 8215856 ECSP_1290 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077211.1 1367752 R 544404 CDS YP_003077212.1 254792375 8215857 1368266..1368538 1 NC_013008.1 hypothetical protein 1368538 8215857 ECSP_1291 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077212.1 1368266 D 544404 CDS YP_003077213.1 254792376 8215858 1368770..1368925 1 NC_013008.1 hypothetical protein 1368925 8215858 ECSP_1292 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077213.1 1368770 D 544404 CDS YP_003077214.1 254792377 8215859 1369103..1369300 1 NC_013008.1 hypothetical protein 1369300 8215859 ECSP_1293 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077214.1 1369103 D 544404 CDS YP_003077215.1 254792378 8215860 1369384..1369503 1 NC_013008.1 hypothetical protein 1369503 8215860 ECSP_1294 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077215.1 1369384 D 544404 CDS YP_003077216.1 254792379 8215861 1370540..1371154 1 NC_013008.1 hypothetical protein 1371154 8215861 ECSP_1295 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077216.1 1370540 D 544404 CDS YP_003077217.1 254792380 8215862 complement(1371296..1371571) 1 NC_013008.1 hypothetical protein 1371571 8215862 ECSP_1296 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077217.1 1371296 R 544404 CDS YP_003077218.1 254792381 8215863 complement(1371573..1371968) 1 NC_013008.1 IS1 protein InsB 1371968 8215863 ECSP_1297 Escherichia coli O157:H7 str. TW14359 IS1 protein InsB YP_003077218.1 1371573 R 544404 CDS YP_003077219.1 254792382 8215864 complement(1371995..1372270) 1 NC_013008.1 IS1 repressor protein InsA 1372270 8215864 ECSP_1298 Escherichia coli O157:H7 str. TW14359 IS1 repressor protein InsA YP_003077219.1 1371995 R 544404 CDS YP_003077220.1 254792383 8215865 complement(1372508..1372966) 1 NC_013008.1 hypothetical protein 1372966 8215865 ECSP_1299 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077220.1 1372508 R 544404 CDS YP_003077221.1 254792384 8215866 1373424..1373933 1 NC_013008.1 hypothetical protein 1373933 8215866 ECSP_1300 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077221.1 1373424 D 544404 CDS YP_003077222.1 254792385 8215867 1374022..1374645 1 NC_013008.1 hypothetical protein 1374645 8215867 ECSP_1301 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077222.1 1374022 D 544404 CDS YP_003077223.1 254792386 8215868 1374741..1374974 1 NC_013008.1 hypothetical protein 1374974 8215868 ECSP_1302 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077223.1 1374741 D 544404 CDS YP_003077224.1 254792387 8215869 complement(1375027..1375218) 1 NC_013008.1 hypothetical protein 1375218 8215869 ECSP_1303 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077224.1 1375027 R 544404 CDS YP_003077225.1 254792388 8215870 1375446..1375568 1 NC_013008.1 hypothetical protein 1375568 8215870 ECSP_1304 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077225.1 1375446 D 544404 CDS YP_003077226.1 254792389 8215871 complement(1375812..1376699) 1 NC_013008.1 transposase 1376699 8215871 ECSP_1305 Escherichia coli O157:H7 str. TW14359 transposase YP_003077226.1 1375812 R 544404 CDS YP_003077227.1 254792390 8215872 complement(1376699..1377025) 1 NC_013008.1 transposase 1377025 8215872 ECSP_1306 Escherichia coli O157:H7 str. TW14359 transposase YP_003077227.1 1376699 R 544404 CDS YP_003077228.1 254792391 8215873 1377188..1378252 1 NC_013008.1 hemolysin activator protein 1378252 8215873 ECSP_1307 Escherichia coli O157:H7 str. TW14359 hemolysin activator protein YP_003077228.1 1377188 D 544404 CDS YP_003077229.1 254792392 8215875 1381674..1382906 1 NC_013008.1 hypothetical protein 1382906 8215875 ECSP_1309 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077229.1 1381674 D 544404 CDS YP_003077230.1 254792393 8215876 1382891..1383529 1 NC_013008.1 hypothetical protein 1383529 8215876 ECSP_1310 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077230.1 1382891 D 544404 CDS YP_003077231.1 254792394 8215877 1383608..1383877 1 NC_013008.1 hypothetical protein 1383877 8215877 ECSP_1311 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077231.1 1383608 D 544404 CDS YP_003077232.1 254792395 8215878 1383898..1384542 1 NC_013008.1 hypothetical protein 1384542 8215878 ECSP_1312 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077232.1 1383898 D 544404 CDS YP_003077233.1 254792396 8215879 1384590..1384745 1 NC_013008.1 hypothetical protein 1384745 8215879 ECSP_1313 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077233.1 1384590 D 544404 CDS YP_003077234.1 254792397 8215880 1384901..1385200 1 NC_013008.1 transposase 1385200 8215880 ECSP_1314 Escherichia coli O157:H7 str. TW14359 transposase YP_003077234.1 1384901 D 544404 CDS YP_003077235.1 254792398 8215881 complement(1385240..1385488) 1 NC_013008.1 transposase 1385488 8215881 ECSP_1315 Escherichia coli O157:H7 str. TW14359 transposase YP_003077235.1 1385240 R 544404 CDS YP_003077236.1 254792399 8215882 1385542..1385967 1 NC_013008.1 hypothetical protein 1385967 8215882 ECSP_1316 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077236.1 1385542 D 544404 CDS YP_003077237.1 254792400 8215883 complement(1386267..1386449) 1 NC_013008.1 hypothetical protein 1386449 8215883 ECSP_1317 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077237.1 1386267 R 544404 CDS YP_003077238.1 254792401 8215884 1386779..1387651 1 NC_013008.1 hypothetical protein 1387651 8215884 ECSP_1318 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077238.1 1386779 D 544404 CDS YP_003077239.1 254792402 8215885 1388023..1390872 1 NC_013008.1 calcium-binding autotransporter 1390872 cah 8215885 cah Escherichia coli O157:H7 str. TW14359 calcium-binding autotransporter YP_003077239.1 1388023 D 544404 CDS YP_003077240.1 254792403 8215886 1390980..1393367 1 NC_013008.1 hypothetical protein 1393367 8215886 ECSP_1320 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077240.1 1390980 D 544404 CDS YP_003077241.1 254792404 8215887 1393364..1394269 1 NC_013008.1 hypothetical protein 1394269 8215887 ECSP_1321 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077241.1 1393364 D 544404 CDS YP_003077242.1 254792405 8215888 1394266..1395336 1 NC_013008.1 hypothetical protein 1395336 8215888 ECSP_1322 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077242.1 1394266 D 544404 CDS YP_003077243.1 254792406 8215889 1395676..1396494 1 NC_013008.1 hypothetical protein 1396494 8215889 ECSP_1323 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077243.1 1395676 D 544404 CDS YP_003077244.1 254792407 8215890 1396585..1397070 1 NC_013008.1 hypothetical protein 1397070 8215890 ECSP_1324 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077244.1 1396585 D 544404 CDS YP_003077245.1 254792408 8215891 1397086..1397562 1 NC_013008.1 DNA repair protein, RADC family 1397562 8215891 ECSP_1325 Escherichia coli O157:H7 str. TW14359 DNA repair protein, RADC family YP_003077245.1 1397086 D 544404 CDS YP_003077246.1 254792409 8215892 1397625..1397846 1 NC_013008.1 hypothetical protein 1397846 8215892 ECSP_1326 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077246.1 1397625 D 544404 CDS YP_003077247.1 254792410 8215893 1397846..1397959 1 NC_013008.1 hypothetical protein 1397959 8215893 ECSP_1327 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077247.1 1397846 D 544404 CDS YP_003077248.1 254792411 8215894 1398009..1398383 1 NC_013008.1 structural protein 1398383 8215894 ECSP_1328 Escherichia coli O157:H7 str. TW14359 structural protein YP_003077248.1 1398009 D 544404 CDS YP_003077249.1 254792412 8215895 1398430..1398804 1 NC_013008.1 hypothetical protein 1398804 8215895 ECSP_1329 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077249.1 1398430 D 544404 CDS YP_003077250.1 254792413 8215896 1398801..1399292 1 NC_013008.1 hypothetical protein 1399292 8215896 ECSP_1330 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077250.1 1398801 D 544404 CDS YP_003077251.1 254792414 8215897 1399304..1399501 1 NC_013008.1 hypothetical protein 1399501 8215897 ECSP_1331 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077251.1 1399304 D 544404 CDS YP_003077252.1 254792415 8215898 1399586..1400428 1 NC_013008.1 hypothetical protein 1400428 8215898 ECSP_1332 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077252.1 1399586 D 544404 CDS YP_003077253.1 254792416 8215900 1400899..1401837 1 NC_013008.1 2-ketoacid reductase 1401837 ycdW 8215900 ycdW Escherichia coli O157:H7 str. TW14359 2-ketoacid reductase YP_003077253.1 1400899 D 544404 CDS YP_003077254.1 254792417 8215901 1401892..1402629 1 NC_013008.1 hydrolase 1402629 ycdX 8215901 ycdX Escherichia coli O157:H7 str. TW14359 hydrolase YP_003077254.1 1401892 D 544404 CDS YP_003077255.1 254792418 8215902 1402653..1403207 1 NC_013008.1 hypothetical protein 1403207 ycdY 8215902 ycdY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077255.1 1402653 D 544404 CDS YP_003077256.1 254792419 8215903 1403309..1403800 1 NC_013008.1 inner membrane protein 1403800 ycdZ 8215903 ycdZ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077256.1 1403309 D 544404 CDS YP_003077257.1 254792420 8215904 complement(1403864..1404697) 1 NC_013008.1 curli production assembly/transport component, 2nd curli operon 1404697 csgG 8215904 csgG Escherichia coli O157:H7 str. TW14359 curli production assembly/transport component, 2nd curli operon YP_003077257.1 1403864 R 544404 CDS YP_003077258.1 254792421 8215905 complement(1404724..1405140) 1 NC_013008.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1405140 csgF 8215905 csgF Escherichia coli O157:H7 str. TW14359 curli assembly protein CsgF YP_003077258.1 1404724 R 544404 CDS YP_003077259.1 254792422 8215906 complement(1405165..1405554) 1 NC_013008.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1405554 csgE 8215906 csgE Escherichia coli O157:H7 str. TW14359 curli assembly protein CsgE YP_003077259.1 1405165 R 544404 CDS YP_003077260.1 254792423 8215907 complement(1405559..1406209) 1 NC_013008.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1406209 csgD 8215907 csgD Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator CsgD YP_003077260.1 1405559 R 544404 CDS YP_003077261.1 254792424 8215908 complement(1406621..1406869) 1 NC_013008.1 hypothetical protein 1406869 8215908 ECSP_1342 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077261.1 1406621 R 544404 CDS YP_003077262.1 254792425 8215909 1406963..1407418 1 NC_013008.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1407418 csgB 8215909 csgB Escherichia coli O157:H7 str. TW14359 curlin minor subunit YP_003077262.1 1406963 D 544404 CDS YP_003077263.1 254792426 8215910 1407459..1407917 1 NC_013008.1 cryptic curlin major subunit 1407917 csgA 8215910 csgA Escherichia coli O157:H7 str. TW14359 cryptic curlin major subunit YP_003077263.1 1407459 D 544404 CDS YP_003077264.1 254792427 8215911 1407976..1408308 1 NC_013008.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1408308 csgC 8215911 csgC Escherichia coli O157:H7 str. TW14359 autoagglutination protein YP_003077264.1 1407976 D 544404 CDS YP_003077265.1 254792428 8215912 1408429..1408740 1 NC_013008.1 hypothetical protein 1408740 ymdA 8215912 ymdA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077265.1 1408429 D 544404 CDS YP_003077266.1 254792429 8215913 1408835..1409368 1 NC_013008.1 hypothetical protein 1409368 ymdB 8215913 ymdB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077266.1 1408835 D 544404 CDS YP_003077267.1 254792430 8215914 1409370..1410791 1 NC_013008.1 hydrolase 1410791 ymdC 8215914 ymdC Escherichia coli O157:H7 str. TW14359 hydrolase YP_003077267.1 1409370 D 544404 CDS YP_003077268.1 254792431 8215915 complement(1410799..1411956) 1 NC_013008.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1411956 mdoC 8215915 mdoC Escherichia coli O157:H7 str. TW14359 glucans biosynthesis protein YP_003077268.1 1410799 R 544404 CDS YP_003077269.1 254792432 8215916 1412349..1413884 1 NC_013008.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1413884 mdoG 8215916 mdoG Escherichia coli O157:H7 str. TW14359 glucan biosynthesis protein G YP_003077269.1 1412349 D 544404 CDS YP_003077270.1 254792433 8215917 1413877..1416420 1 NC_013008.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1416420 mdoH 8215917 mdoH Escherichia coli O157:H7 str. TW14359 glucosyltransferase MdoH YP_003077270.1 1413877 D 544404 CDS YP_003077271.1 254792434 8215918 1416593..1416820 1 NC_013008.1 hypothetical protein 1416820 yceK 8215918 yceK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077271.1 1416593 D 544404 CDS YP_003077272.1 254792435 8215919 complement(1416821..1417195) 1 NC_013008.1 hypothetical protein 1417195 msyB 8215919 msyB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077272.1 1416821 R 544404 CDS YP_003077273.1 254792436 8215921 complement(1418676..1419596) 1 NC_013008.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1419596 lpxL 8215921 lpxL Escherichia coli O157:H7 str. TW14359 lipid A biosynthesis lauroyl acyltransferase YP_003077273.1 1418676 R 544404 CDS YP_003077274.1 254792437 8215922 1419821..1420873 1 NC_013008.1 hypothetical protein 1420873 yceA 8215922 yceA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077274.1 1419821 D 544404 CDS YP_003077275.1 254792438 8215923 complement(1420915..1421490) 1 NC_013008.1 hypothetical protein 1421490 yceI 8215923 yceI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077275.1 1420915 R 544404 CDS YP_003077276.1 254792439 8215924 complement(1421494..1422060) 1 NC_013008.1 cytochrome b561 1422060 yceJ 8215924 yceJ Escherichia coli O157:H7 str. TW14359 cytochrome b561 YP_003077276.1 1421494 R 544404 CDS YP_003077277.1 254792440 8215925 complement(1422321..1422461) 1 NC_013008.1 hypothetical protein 1422461 yceO 8215925 yceO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077277.1 1422321 R 544404 CDS YP_003077278.1 254792441 8215926 complement(1422482..1423600) 1 NC_013008.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1423600 solA 8215926 solA Escherichia coli O157:H7 str. TW14359 N-methyltryptophan oxidase YP_003077278.1 1422482 R 544404 CDS YP_003077279.1 254792442 8215927 complement(1423715..1423969) 1 NC_013008.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1423969 bssS 8215927 bssS Escherichia coli O157:H7 str. TW14359 biofilm formation regulatory protein BssS YP_003077279.1 1423715 R 544404 CDS YP_003077280.1 254792443 8215928 complement(1424259..1424504) 1 NC_013008.1 DNA damage-inducible protein I 1424504 dinI 8215928 dinI Escherichia coli O157:H7 str. TW14359 DNA damage-inducible protein I YP_003077280.1 1424259 R 544404 CDS YP_003077281.1 254792444 8215929 complement(1424578..1425624) 1 NC_013008.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1425624 pyrC 8215929 pyrC Escherichia coli O157:H7 str. TW14359 dihydroorotase YP_003077281.1 1424578 R 544404 CDS YP_003077282.1 254792445 8215930 complement(1425730..1426290) 1 NC_013008.1 hypothetical protein 1426290 yceB 8215930 yceB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077282.1 1425730 R 544404 CDS YP_003077283.1 254792446 8215931 complement(1426424..1427071) 1 NC_013008.1 cofactor involved in the reduction of disulfides; glutaredoxin 2 1427071 grxB 8215931 grxB Escherichia coli O157:H7 str. TW14359 glutaredoxin 2 YP_003077283.1 1426424 R 544404 CDS YP_003077284.1 254792447 8215932 complement(1427135..1428343) 1 NC_013008.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1428343 mdtH 8215932 mdtH Escherichia coli O157:H7 str. TW14359 multidrug resistance protein MdtH YP_003077284.1 1427135 R 544404 CDS YP_003077285.1 254792448 8215933 1428579..1429163 1 NC_013008.1 ribosomal-protein-S5-alanine N-acetyltransferase 1429163 rimJ 8215933 rimJ Escherichia coli O157:H7 str. TW14359 ribosomal-protein-S5-alanine N-acetyltransferase YP_003077285.1 1428579 D 544404 CDS YP_003077286.1 254792449 8215934 1429174..1429821 1 NC_013008.1 hypothetical protein 1429821 yceH 8215934 yceH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077286.1 1429174 D 544404 CDS YP_003077287.1 254792450 8215935 1429823..1430746 1 NC_013008.1 oxidoreductase 1430746 mviM 8215935 mviM Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077287.1 1429823 D 544404 CDS YP_003077288.1 254792451 8215936 1430856..1432391 1 NC_013008.1 inner membrane protein 1432391 yceN 8215936 yceN Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077288.1 1430856 D 544404 CDS YP_003077289.1 254792452 8215937 complement(1432431..1432847) 1 NC_013008.1 export chaperone for FlgK and FlgL 1432847 flgN 8215937 flgN Escherichia coli O157:H7 str. TW14359 export chaperone for FlgK and FlgL YP_003077289.1 1432431 R 544404 CDS YP_003077290.1 254792453 8215938 complement(1432852..1433145) 1 NC_013008.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM 1433145 flgM 8215938 flgM Escherichia coli O157:H7 str. TW14359 anti-sigma28 factor FlgM YP_003077290.1 1432852 R 544404 CDS YP_003077291.1 254792454 8215939 complement(1433221..1433880) 1 NC_013008.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1433880 flgA 8215939 flgA Escherichia coli O157:H7 str. TW14359 flagellar basal body P-ring biosynthesis protein FlgA YP_003077291.1 1433221 R 544404 CDS YP_003077292.1 254792455 8215940 1434035..1434451 1 NC_013008.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1434451 flgB 8215940 flgB Escherichia coli O157:H7 str. TW14359 flagellar basal-body rod protein FlgB YP_003077292.1 1434035 D 544404 CDS YP_003077293.1 254792456 8215941 1434455..1434859 1 NC_013008.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1434859 flgC 8215941 flgC Escherichia coli O157:H7 str. TW14359 flagellar basal body rod protein FlgC YP_003077293.1 1434455 D 544404 CDS YP_003077294.1 254792457 8215942 1434871..1435566 1 NC_013008.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1435566 flgD 8215942 flgD Escherichia coli O157:H7 str. TW14359 flagellar basal body rod modification protein YP_003077294.1 1434871 D 544404 CDS YP_003077295.1 254792458 8215943 1435591..1436796 1 NC_013008.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1436796 flgE 8215943 flgE Escherichia coli O157:H7 str. TW14359 flagellar hook protein FlgE YP_003077295.1 1435591 D 544404 CDS YP_003077296.1 254792459 8215944 1436816..1437571 1 NC_013008.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1437571 flgF 8215944 flgF Escherichia coli O157:H7 str. TW14359 flagellar basal body rod protein FlgF YP_003077296.1 1436816 D 544404 CDS YP_003077297.1 254792460 8215945 1437709..1438491 1 NC_013008.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1438491 flgG 8215945 flgG Escherichia coli O157:H7 str. TW14359 flagellar basal body rod protein FlgG YP_003077297.1 1437709 D 544404 CDS YP_003077298.1 254792461 8215946 1438544..1439242 1 NC_013008.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1439242 flgH 8215946 flgH Escherichia coli O157:H7 str. TW14359 flagellar basal body L-ring protein YP_003077298.1 1438544 D 544404 CDS YP_003077299.1 254792462 8215947 1439254..1440351 1 NC_013008.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1440351 flgI 8215947 flgI Escherichia coli O157:H7 str. TW14359 flagellar basal body P-ring protein YP_003077299.1 1439254 D 544404 CDS YP_003077300.1 254792463 8215948 1440351..1441292 1 NC_013008.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1441292 flgJ 8215948 flgJ Escherichia coli O157:H7 str. TW14359 flagellar rod assembly protein/muramidase FlgJ YP_003077300.1 1440351 D 544404 CDS YP_003077301.1 254792464 8215949 1441358..1443001 1 NC_013008.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1443001 flgK 8215949 flgK Escherichia coli O157:H7 str. TW14359 flagellar hook-associated protein FlgK YP_003077301.1 1441358 D 544404 CDS YP_003077302.1 254792465 8215950 1443013..1443966 1 NC_013008.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1443966 flgL 8215950 flgL Escherichia coli O157:H7 str. TW14359 flagellar hook-associated protein FlgL YP_003077302.1 1443013 D 544404 CDS YP_003077303.1 254792466 8215951 complement(1444161..1447346) 1 NC_013008.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1447346 rne 8215951 rne Escherichia coli O157:H7 str. TW14359 ribonuclease E YP_003077303.1 1444161 R 544404 CDS YP_003077304.1 254792467 8215952 1447481..1447801 1 NC_013008.1 hypothetical protein 1447801 yceQ 8215952 yceQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077304.1 1447481 D 544404 CDS YP_003077305.1 254792468 8215953 1447919..1448878 1 NC_013008.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1448878 rluC 8215953 rluC Escherichia coli O157:H7 str. TW14359 23S rRNA pseudouridylate synthase C YP_003077305.1 1447919 D 544404 CDS YP_003077306.1 254792469 8215954 complement(1448979..1449563) 1 NC_013008.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1449563 yceF 8215954 yceF Escherichia coli O157:H7 str. TW14359 Maf-like protein YP_003077306.1 1448979 R 544404 CDS YP_003077307.1 254792470 8215955 1449762..1450283 1 NC_013008.1 hypothetical protein 1450283 yceD 8215955 yceD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077307.1 1449762 D 544404 CDS YP_003077308.1 254792471 8215956 1450335..1450508 1 NC_013008.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1450508 rpmF 8215956 rpmF Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L32 YP_003077308.1 1450335 D 544404 CDS YP_003077309.1 254792472 8215957 1450589..1451659 1 NC_013008.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1451659 plsX 8215957 plsX Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate acyltransferase PlsX YP_003077309.1 1450589 D 544404 CDS YP_003077310.1 254792473 8215958 1451727..1452680 1 NC_013008.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1452680 fabH 8215958 fabH Escherichia coli O157:H7 str. TW14359 3-oxoacyl-ACP synthase YP_003077310.1 1451727 D 544404 CDS YP_003077311.1 254792474 8215959 1452696..1453625 1 NC_013008.1 malonyl CoA-ACP transacylase 1453625 fabD 8215959 fabD Escherichia coli O157:H7 str. TW14359 malonyl CoA-ACP transacylase YP_003077311.1 1452696 D 544404 CDS YP_003077312.1 254792475 8215960 1453638..1454372 1 NC_013008.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1454372 fabG 8215960 fabG Escherichia coli O157:H7 str. TW14359 3-ketoacyl-ACP reductase YP_003077312.1 1453638 D 544404 CDS YP_003077313.1 254792476 8215961 1454583..1454819 1 NC_013008.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1454819 acpP 8215961 acpP Escherichia coli O157:H7 str. TW14359 acyl carrier protein YP_003077313.1 1454583 D 544404 CDS YP_003077314.1 254792477 8215962 1454907..1456148 1 NC_013008.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1456148 fabF 8215962 fabF Escherichia coli O157:H7 str. TW14359 3-oxoacyl-ACP synthase YP_003077314.1 1454907 D 544404 CDS YP_003077315.1 254792478 8215963 1456268..1457077 1 NC_013008.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1457077 pabC 8215963 pabC Escherichia coli O157:H7 str. TW14359 4-amino-4-deoxychorismate lyase YP_003077315.1 1456268 D 544404 CDS YP_003077316.1 254792479 8215964 1457080..1458102 1 NC_013008.1 hypothetical protein 1458102 yceG 8215964 yceG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077316.1 1457080 D 544404 CDS YP_003077317.1 254792480 8215965 1458092..1458733 1 NC_013008.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1458733 tmk 8215965 tmk Escherichia coli O157:H7 str. TW14359 thymidylate kinase YP_003077317.1 1458092 D 544404 CDS YP_003077318.1 254792481 8215966 1458730..1459734 1 NC_013008.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1459734 holB 8215966 holB Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit delta' YP_003077318.1 1458730 D 544404 CDS YP_003077319.1 254792482 8215967 1459745..1460542 1 NC_013008.1 metallodependent hydrolase 1460542 ycfH 8215967 ycfH Escherichia coli O157:H7 str. TW14359 metallodependent hydrolase YP_003077319.1 1459745 D 544404 CDS YP_003077320.1 254792483 8215968 1460837..1462270 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1462270 ptsG 8215968 ptsG Escherichia coli O157:H7 str. TW14359 PTS system glucose-specific transporter subunits IIBC YP_003077320.1 1460837 D 544404 CDS YP_003077321.1 254792484 8215969 complement(1462330..1464519) 1 NC_013008.1 ferric-rhodotorulic acid outer membrane transporter 1464519 fhuE 8215969 fhuE Escherichia coli O157:H7 str. TW14359 ferric-rhodotorulic acid outer membrane transporter YP_003077321.1 1462330 R 544404 CDS YP_003077322.1 254792485 8215970 complement(1464552..1464740) 1 NC_013008.1 hypothetical protein 1464740 8215970 ECSP_1404 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077322.1 1464552 R 544404 CDS YP_003077323.1 254792486 8215971 1464871..1465230 1 NC_013008.1 purine nucleoside phosphoramidase 1465230 hinT 8215971 hinT Escherichia coli O157:H7 str. TW14359 purine nucleoside phosphoramidase YP_003077323.1 1464871 D 544404 CDS YP_003077324.1 254792487 8215972 1465233..1465610 1 NC_013008.1 lipoprotein 1465610 ycfL 8215972 ycfL Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003077324.1 1465233 D 544404 CDS YP_003077325.1 254792488 8215973 1465624..1466265 1 NC_013008.1 outer membrane lipoprotein 1466265 ycfM 8215973 ycfM Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003077325.1 1465624 D 544404 CDS YP_003077326.1 254792489 8215974 1466246..1467070 1 NC_013008.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1467070 thiK 8215974 thiK Escherichia coli O157:H7 str. TW14359 thiamine kinase YP_003077326.1 1466246 D 544404 CDS YP_003077327.1 254792490 8215975 1467081..1468106 1 NC_013008.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1468106 nagZ 8215975 nagZ Escherichia coli O157:H7 str. TW14359 beta-hexosaminidase YP_003077327.1 1467081 D 544404 CDS YP_003077328.1 254792491 8215976 1468129..1468671 1 NC_013008.1 hypothetical protein 1468671 ycfP 8215976 ycfP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077328.1 1468129 D 544404 CDS YP_003077329.1 254792492 8215977 1469071..1470375 1 NC_013008.1 respiratory NADH dehydrogenase 2/cupric reductase 1470375 ndh 8215977 ndh Escherichia coli O157:H7 str. TW14359 respiratory NADH dehydrogenase 2/cupric reductase YP_003077329.1 1469071 D 544404 CDS YP_003077330.1 254792493 8215978 1470602..1471141 1 NC_013008.1 hypothetical protein 1471141 ycfJ 8215978 ycfJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077330.1 1470602 D 544404 CDS YP_003077331.1 254792494 8215979 complement(1471203..1471835) 1 NC_013008.1 DNA-binding transcriptional regulator 1471835 ycfQ 8215979 ycfQ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077331.1 1471203 R 544404 CDS YP_003077332.1 254792495 8215980 1472076..1472333 1 NC_013008.1 hypothetical protein 1472333 ycfR 8215980 ycfR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077332.1 1472076 D 544404 CDS YP_003077333.1 254792496 8215981 complement(1472416..1473378) 1 NC_013008.1 hypothetical protein 1473378 ycfS 8215981 ycfS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077333.1 1472416 R 544404 CDS YP_003077334.1 254792497 8215982 complement(1473522..1476968) 1 NC_013008.1 transcription-repair coupling factor 1476968 mfd 8215982 mfd Escherichia coli O157:H7 str. TW14359 transcription-repair coupling factor YP_003077334.1 1473522 R 544404 CDS YP_003077335.1 254792498 8215983 complement(1477096..1478169) 1 NC_013008.1 inner membrane protein 1478169 ycfT 8215983 ycfT Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077335.1 1477096 R 544404 CDS YP_003077336.1 254792499 8215984 1478431..1479630 1 NC_013008.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1479630 lolC 8215984 lolC Escherichia coli O157:H7 str. TW14359 outer membrane-specific lipoprotein transporter subunit LolC YP_003077336.1 1478431 D 544404 CDS YP_003077337.1 254792500 8215985 1479623..1480324 1 NC_013008.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1480324 lolD 8215985 lolD Escherichia coli O157:H7 str. TW14359 lipoprotein transporter ATP-binding subunit YP_003077337.1 1479623 D 544404 CDS YP_003077338.1 254792501 8215986 1480324..1481568 1 NC_013008.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1481568 lolE 8215986 lolE Escherichia coli O157:H7 str. TW14359 outer membrane-specific lipoprotein transporter subunit LolE YP_003077338.1 1480324 D 544404 CDS YP_003077339.1 254792502 8215987 1481597..1482508 1 NC_013008.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1482508 ycfX 8215987 ycfX Escherichia coli O157:H7 str. TW14359 N-acetyl-D-glucosamine kinase YP_003077339.1 1481597 D 544404 CDS YP_003077340.1 254792503 8215988 1482524..1483345 1 NC_013008.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1483345 cobB 8215988 cobB Escherichia coli O157:H7 str. TW14359 NAD-dependent deacetylase YP_003077340.1 1482524 D 544404 CDS YP_003077341.1 254792504 8215989 complement(1483501..1484547) 1 NC_013008.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1484547 potD 8215989 potD Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter substrate-binding protein YP_003077341.1 1483501 R 544404 CDS YP_003077342.1 254792505 8215990 complement(1484544..1485338) 1 NC_013008.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1485338 potC 8215990 potC Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter membrane protein YP_003077342.1 1484544 R 544404 CDS YP_003077343.1 254792506 8215991 complement(1485505..1486623) 1 NC_013008.1 integrase for prophage CP-933N 1486623 intN 8215991 intN Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933N YP_003077343.1 1485505 R 544404 CDS YP_003077344.1 254792507 8215992 complement(1486592..1486861) 1 NC_013008.1 excisionase for prophage CP-933N 1486861 xisN 8215992 xisN Escherichia coli O157:H7 str. TW14359 excisionase for prophage CP-933N YP_003077344.1 1486592 R 544404 CDS YP_003077345.1 254792508 8215993 complement(1486923..1487267) 1 NC_013008.1 hypothetical protein 1487267 8215993 ECSP_1427 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077345.1 1486923 R 544404 CDS YP_003077346.1 254792509 8215994 1487445..1487960 1 NC_013008.1 hypothetical protein 1487960 8215994 ECSP_1428 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077346.1 1487445 D 544404 CDS YP_003077347.1 254792510 8215995 complement(1488075..1488305) 1 NC_013008.1 hypothetical protein 1488305 8215995 ECSP_1429 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077347.1 1488075 R 544404 CDS YP_003077348.1 254792511 8215996 complement(1488543..1489019) 1 NC_013008.1 hypothetical protein 1489019 8215996 ECSP_1430 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077348.1 1488543 R 544404 CDS YP_003077349.1 254792512 8215997 1489144..1489467 1 NC_013008.1 hypothetical protein 1489467 8215997 ECSP_1431 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077349.1 1489144 D 544404 CDS YP_003077350.1 254792513 8215998 1489451..1489876 1 NC_013008.1 hypothetical protein 1489876 8215998 ECSP_1432 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077350.1 1489451 D 544404 CDS YP_003077351.1 254792514 8215999 1489945..1490982 1 NC_013008.1 hypothetical protein 1490982 8215999 ECSP_1433 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077351.1 1489945 D 544404 CDS YP_003077352.1 254792515 8216000 1491014..1491436 1 NC_013008.1 hypothetical protein 1491436 8216000 ECSP_1434 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077352.1 1491014 D 544404 CDS YP_003077353.1 254792516 8216001 1491470..1492186 1 NC_013008.1 hypothetical protein 1492186 8216001 ECSP_1435 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077353.1 1491470 D 544404 CDS YP_003077354.1 254792517 8216002 1492183..1492500 1 NC_013008.1 hypothetical protein 1492500 8216002 ECSP_1436 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077354.1 1492183 D 544404 CDS YP_003077355.1 254792518 8216003 1492497..1492799 1 NC_013008.1 hypothetical protein 1492799 8216003 ECSP_1437 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077355.1 1492497 D 544404 CDS YP_003077356.1 254792519 8216004 1492789..1493106 1 NC_013008.1 hypothetical protein 1493106 8216004 ECSP_1438 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077356.1 1492789 D 544404 CDS YP_003077357.1 254792520 8216005 1493108..1493377 1 NC_013008.1 hypothetical protein 1493377 8216005 ECSP_1439 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077357.1 1493108 D 544404 CDS YP_003077358.1 254792521 8216006 1493364..1493801 1 NC_013008.1 hypothetical protein 1493801 8216006 ECSP_1440 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077358.1 1493364 D 544404 CDS YP_003077359.1 254792522 8216007 1493997..1494584 1 NC_013008.1 hypothetical protein 1494584 8216007 ECSP_1441 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077359.1 1493997 D 544404 CDS YP_003077360.1 254792523 8216008 1494993..1495205 1 NC_013008.1 Gef-like protein encoded by prophage CP-933N 1495205 8216008 ECSP_1442 Escherichia coli O157:H7 str. TW14359 Gef-like protein encoded by prophage CP-933N YP_003077360.1 1494993 D 544404 CDS YP_003077361.1 254792524 8216009 1495242..1495337 1 NC_013008.1 hypothetical protein 1495337 8216009 ECSP_1443 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077361.1 1495242 D 544404 CDS YP_003077362.1 254792525 8216010 complement(1495391..1495570) 1 NC_013008.1 hypothetical protein 1495570 8216010 ECSP_1444 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077362.1 1495391 R 544404 CDS YP_003077363.1 254792526 8216011 1495653..1496702 1 NC_013008.1 hypothetical protein 1496702 8216011 ECSP_1445 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077363.1 1495653 D 544404 CDS YP_003077364.1 254792527 8216012 1496715..1496972 1 NC_013008.1 hypothetical protein 1496972 8216012 ECSP_1446 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077364.1 1496715 D 544404 CDS YP_003077365.1 254792528 8216013 1496953..1498245 1 NC_013008.1 hypothetical protein 1498245 8216013 ECSP_1447 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077365.1 1496953 D 544404 CDS YP_003077366.1 254792529 8216014 1498393..1498575 1 NC_013008.1 hypothetical protein 1498575 8216014 ECSP_1448 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077366.1 1498393 D 544404 CDS YP_003077367.1 254792530 8216015 1498613..1498882 1 NC_013008.1 hypothetical protein 1498882 8216015 ECSP_1449 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077367.1 1498613 D 544404 CDS YP_003077368.1 254792531 8216016 1498958..1499173 1 NC_013008.1 hypothetical protein 1499173 8216016 ECSP_1450 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077368.1 1498958 D 544404 CDS YP_003077369.1 254792532 8216017 1499178..1499522 1 NC_013008.1 hypothetical protein 1499522 8216017 ECSP_1451 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077369.1 1499178 D 544404 CDS YP_003077370.1 254792533 8216018 1499573..1500106 1 NC_013008.1 endolysin of prophage CP-933N 1500106 8216018 ECSP_1452 Escherichia coli O157:H7 str. TW14359 endolysin of prophage CP-933N YP_003077370.1 1499573 D 544404 CDS YP_003077371.1 254792534 8216019 1500377..1500946 1 NC_013008.1 antirepressor protein 1500946 8216019 ECSP_1453 Escherichia coli O157:H7 str. TW14359 antirepressor protein YP_003077371.1 1500377 D 544404 CDS YP_003077372.1 254792535 8216020 1501100..1501567 1 NC_013008.1 bacteriophage lysis protein 1501567 8216020 ECSP_1454 Escherichia coli O157:H7 str. TW14359 bacteriophage lysis protein YP_003077372.1 1501100 D 544404 CDS YP_003077373.1 254792536 8216021 1501591..1501815 1 NC_013008.1 hypothetical protein 1501815 8216021 ECSP_1455 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077373.1 1501591 D 544404 CDS YP_003077374.1 254792537 8216022 1501963..1502085 1 NC_013008.1 hypothetical protein 1502085 8216022 ECSP_1456 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077374.1 1501963 D 544404 CDS YP_003077375.1 254792538 8216023 1502172..1502312 1 NC_013008.1 hypothetical protein 1502312 8216023 ECSP_1457 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077375.1 1502172 D 544404 CDS YP_003077376.1 254792539 8216024 1502669..1503034 1 NC_013008.1 HNH endonuclease 1503034 8216024 ECSP_1458 Escherichia coli O157:H7 str. TW14359 HNH endonuclease YP_003077376.1 1502669 D 544404 CDS YP_003077377.1 254792540 8216025 1503324..1503887 1 NC_013008.1 hypothetical protein 1503887 8216025 ECSP_1459 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077377.1 1503324 D 544404 CDS YP_003077378.1 254792541 8216026 1503884..1505545 1 NC_013008.1 phage terminase, large subunit 1505545 8216026 ECSP_1460 Escherichia coli O157:H7 str. TW14359 phage terminase, large subunit YP_003077378.1 1503884 D 544404 CDS YP_003077379.1 254792542 8216027 1505609..1507546 1 NC_013008.1 prohead protease 1507546 8216027 ECSP_1461 Escherichia coli O157:H7 str. TW14359 prohead protease YP_003077379.1 1505609 D 544404 CDS YP_003077380.1 254792543 8216028 1507758..1510259 1 NC_013008.1 portal protein 1510259 8216028 ECSP_1462 Escherichia coli O157:H7 str. TW14359 portal protein YP_003077380.1 1507758 D 544404 CDS YP_003077381.1 254792544 8216029 1510339..1510665 1 NC_013008.1 hypothetical protein 1510665 8216029 ECSP_1463 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077381.1 1510339 D 544404 CDS YP_003077382.1 254792545 8216030 1510675..1511025 1 NC_013008.1 head-tail adaptor 1511025 8216030 ECSP_1464 Escherichia coli O157:H7 str. TW14359 head-tail adaptor YP_003077382.1 1510675 D 544404 CDS YP_003077383.1 254792546 8216031 1511022..1511468 1 NC_013008.1 hypothetical protein 1511468 8216031 ECSP_1465 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077383.1 1511022 D 544404 CDS YP_003077384.1 254792547 8216032 1511465..1511809 1 NC_013008.1 hypothetical protein 1511809 8216032 ECSP_1466 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077384.1 1511465 D 544404 CDS YP_003077385.1 254792548 8216033 1511875..1512591 1 NC_013008.1 hypothetical protein 1512591 8216033 ECSP_1467 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077385.1 1511875 D 544404 CDS YP_003077386.1 254792549 8216034 1512558..1512980 1 NC_013008.1 tail assembly chaperone encoded by prophage CP-933N 1512980 8216034 ECSP_1468 Escherichia coli O157:H7 str. TW14359 tail assembly chaperone encoded by prophage CP-933N YP_003077386.1 1512558 D 544404 CDS YP_003077387.1 254792550 8216035 1513082..1513285 1 NC_013008.1 hypothetical protein 1513285 8216035 ECSP_1469 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077387.1 1513082 D 544404 CDS YP_003077388.1 254792551 8216036 1513338..1516580 1 NC_013008.1 tail length tape measure protein 1516580 8216036 ECSP_1470 Escherichia coli O157:H7 str. TW14359 tail length tape measure protein YP_003077388.1 1513338 D 544404 CDS YP_003077389.1 254792552 8216037 1516573..1516914 1 NC_013008.1 minor tail protein 1516914 8216037 ECSP_1471 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077389.1 1516573 D 544404 CDS YP_003077390.1 254792553 8216038 1516914..1517612 1 NC_013008.1 minor tail protein 1517612 8216038 ECSP_1472 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077390.1 1516914 D 544404 CDS YP_003077391.1 254792554 8216039 complement(1517629..1517883) 1 NC_013008.1 hypothetical protein 1517883 8216039 ECSP_1473 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077391.1 1517629 R 544404 CDS YP_003077392.1 254792555 8216040 1517993..1518103 1 NC_013008.1 hypothetical protein 1518103 8216040 ECSP_1474 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077392.1 1517993 D 544404 CDS YP_003077393.1 254792556 8216041 1518406..1519284 1 NC_013008.1 antirepressor protein encoded by prophage CP-933N 1519284 8216041 ECSP_1475 Escherichia coli O157:H7 str. TW14359 antirepressor protein encoded by prophage CP-933N YP_003077393.1 1518406 D 544404 CDS YP_003077394.1 254792557 8216042 1519338..1520075 1 NC_013008.1 encoded by prophage CP-933N; tail component K-like protein 1520075 8216042 ECSP_1476 Escherichia coli O157:H7 str. TW14359 tail component K-like protein YP_003077394.1 1519338 D 544404 CDS YP_003077395.1 254792558 8216043 1520072..1520257 1 NC_013008.1 hypothetical protein 1520257 8216043 ECSP_1477 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077395.1 1520072 D 544404 CDS YP_003077396.1 254792559 8216044 1520778..1522727 1 NC_013008.1 non-LEE-encoded type III effector 1522727 espX7 8216044 espX7 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077396.1 1520778 D 544404 CDS YP_003077397.1 254792560 8216045 1523906..1526719 1 NC_013008.1 non-LEE-encoded type III effector 1526719 espN 8216045 espN Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077397.1 1523906 D 544404 CDS YP_003077398.1 254792561 8216046 complement(1527262..1528167) 1 NC_013008.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 1528167 8216046 ECSP_1480 Escherichia coli O157:H7 str. TW14359 insertion element IS2 transposase InsD YP_003077398.1 1527262 R 544404 CDS YP_003077399.1 254792562 8216048 1528447..1528800 1 NC_013008.1 IS encoded protein 1528800 8216048 ECSP_1482 Escherichia coli O157:H7 str. TW14359 IS encoded protein YP_003077399.1 1528447 D 544404 CDS YP_003077400.1 254792563 8216049 complement(1529028..1529303) 1 NC_013008.1 non-LEE-encoded type III effector 1529303 8216049 ECSP_1483 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077400.1 1529028 R 544404 CDS YP_003077401.1 254792564 8216050 complement(1529364..1530725) 1 NC_013008.1 non-LEE-encoded type III effector 1530725 espK 8216050 espK Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077401.1 1529364 R 544404 CDS YP_003077402.1 254792565 8216051 complement(1531089..1531922) 1 NC_013008.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1531922 potB 8216051 potB Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter membrane protein YP_003077402.1 1531089 R 544404 CDS YP_003077403.1 254792566 8216052 complement(1531936..1533072) 1 NC_013008.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 1533072 potA 8216052 potA Escherichia coli O157:H7 str. TW14359 putrescine/spermidine ABC transporter ATPase protein YP_003077403.1 1531936 R 544404 CDS YP_003077404.1 254792567 8216053 1533322..1534548 1 NC_013008.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1534548 pepT 8216053 pepT Escherichia coli O157:H7 str. TW14359 peptidase T YP_003077404.1 1533322 D 544404 CDS YP_003077405.1 254792568 8216054 complement(1534597..1535718) 1 NC_013008.1 hypothetical protein 1535718 ycfD 8216054 ycfD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077405.1 1534597 R 544404 CDS YP_003077406.1 254792569 8216055 complement(1535798..1535962) 1 NC_013008.1 hypothetical protein 1535962 8216055 ECSP_1489 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077406.1 1535798 R 544404 CDS YP_003077407.1 254792570 8216056 1535967..1537196 1 NC_013008.1 integrase of prophage CP-933C 1537196 8216056 ECSP_1490 Escherichia coli O157:H7 str. TW14359 integrase of prophage CP-933C YP_003077407.1 1535967 D 544404 CDS YP_003077408.1 254792571 8216057 1537561..1537749 1 NC_013008.1 DNA binding protein 1537749 8216057 ECSP_1491 Escherichia coli O157:H7 str. TW14359 DNA binding protein YP_003077408.1 1537561 D 544404 CDS YP_003077409.1 254792572 8216058 1537807..1538751 1 NC_013008.1 hypothetical protein 1538751 8216058 ECSP_1492 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077409.1 1537807 D 544404 CDS YP_003077410.1 254792573 8216059 1538744..1538956 1 NC_013008.1 hypothetical protein 1538956 8216059 ECSP_1493 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077410.1 1538744 D 544404 CDS YP_003077411.1 254792574 8216060 1538946..1539410 1 NC_013008.1 hypothetical protein 1539410 8216060 ECSP_1494 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077411.1 1538946 D 544404 CDS YP_003077412.1 254792575 8216061 1539403..1539636 1 NC_013008.1 hypothetical protein 1539636 8216061 ECSP_1495 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077412.1 1539403 D 544404 CDS YP_003077413.1 254792576 8216062 1539642..1539941 1 NC_013008.1 hypothetical protein 1539941 8216062 ECSP_1496 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077413.1 1539642 D 544404 CDS YP_003077414.1 254792577 8216063 1539938..1541338 1 NC_013008.1 hypothetical protein 1541338 8216063 ECSP_1497 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077414.1 1539938 D 544404 CDS YP_003077415.1 254792578 8216064 1541539..1541790 1 NC_013008.1 hypothetical protein 1541790 8216064 ECSP_1498 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077415.1 1541539 D 544404 CDS YP_003077416.1 254792579 8216065 1541787..1542197 1 NC_013008.1 single stranded DNA-binding protein of prophage CP-933C 1542197 8216065 ECSP_1499 Escherichia coli O157:H7 str. TW14359 single stranded DNA-binding protein of prophage CP-933C YP_003077416.1 1541787 D 544404 CDS YP_003077417.1 254792580 8216066 1542208..1542480 1 NC_013008.1 transcriptional activator 1542480 8216066 ECSP_1500 Escherichia coli O157:H7 str. TW14359 transcriptional activator YP_003077417.1 1542208 D 544404 CDS YP_003077418.1 254792581 8216067 1542607..1542831 1 NC_013008.1 hypothetical protein 1542831 8216067 ECSP_1501 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077418.1 1542607 D 544404 CDS YP_003077419.1 254792582 8216068 1543083..1543289 1 NC_013008.1 hypothetical protein 1543289 8216068 ECSP_1502 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077419.1 1543083 D 544404 CDS YP_003077420.1 254792583 8216069 1543289..1544344 1 NC_013008.1 capsid protein of prophage 1544344 8216069 ECSP_1503 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage YP_003077420.1 1543289 D 544404 CDS YP_003077421.1 254792584 8216070 1544357..1544692 1 NC_013008.1 hypothetical protein 1544692 8216070 ECSP_1504 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077421.1 1544357 D 544404 CDS YP_003077422.1 254792585 8216071 1544705..1545118 1 NC_013008.1 hypothetical protein 1545118 8216071 ECSP_1505 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077422.1 1544705 D 544404 CDS YP_003077423.1 254792586 8216072 1545339..1545866 1 NC_013008.1 DNA packaging protein 1545866 8216072 ECSP_1506 Escherichia coli O157:H7 str. TW14359 DNA packaging protein YP_003077423.1 1545339 D 544404 CDS YP_003077424.1 254792587 8216073 1546122..1546403 1 NC_013008.1 hypothetical protein 1546403 8216073 ECSP_1507 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077424.1 1546122 D 544404 CDS YP_003077425.1 254792588 8216074 complement(1546584..1546727) 1 NC_013008.1 hypothetical protein 1546727 8216074 ECSP_1508 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077425.1 1546584 R 544404 CDS YP_003077426.1 254792589 8216075 complement(1547004..1548464) 1 NC_013008.1 sensor protein PhoQ 1548464 phoQ 8216075 phoQ Escherichia coli O157:H7 str. TW14359 sensor protein PhoQ YP_003077426.1 1547004 R 544404 CDS YP_003077427.1 254792590 8216076 complement(1548464..1549135) 1 NC_013008.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1549135 phoP 8216076 phoP Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator PhoP YP_003077427.1 1548464 R 544404 CDS YP_003077428.1 254792591 8216077 complement(1549304..1550674) 1 NC_013008.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1550674 purB 8216077 purB Escherichia coli O157:H7 str. TW14359 adenylosuccinate lyase YP_003077428.1 1549304 R 544404 CDS YP_003077429.1 254792592 8216078 complement(1550678..1551319) 1 NC_013008.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1551319 hflD 8216078 hflD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077429.1 1550678 R 544404 CDS YP_003077430.1 254792593 8216079 complement(1551355..1552461) 1 NC_013008.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1552461 mnmA 8216079 mnmA Escherichia coli O157:H7 str. TW14359 tRNA-specific 2-thiouridylase MnmA YP_003077430.1 1551355 R 544404 CDS YP_003077431.1 254792594 8216080 complement(1552515..1552976) 1 NC_013008.1 thiamin pyrophosphate (TPP) hydrolase 1552976 nudJ 8216080 nudJ Escherichia coli O157:H7 str. TW14359 thiamin pyrophosphate (TPP) hydrolase YP_003077431.1 1552515 R 544404 CDS YP_003077432.1 254792595 8216081 complement(1552986..1553639) 1 NC_013008.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1553639 rluE 8216081 rluE Escherichia coli O157:H7 str. TW14359 23S rRNA pseudouridine synthase E YP_003077432.1 1552986 R 544404 CDS YP_003077433.1 254792596 8216082 1553811..1555061 1 NC_013008.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1555061 icd 8216082 icd Escherichia coli O157:H7 str. TW14359 isocitrate dehydrogenase YP_003077433.1 1553811 D 544404 CDS YP_003077434.1 254792597 8216083 complement(1555175..1556317) 1 NC_013008.1 integrase of prophage CP-933X 1556317 8216083 ECSP_1517 Escherichia coli O157:H7 str. TW14359 integrase of prophage CP-933X YP_003077434.1 1555175 R 544404 CDS YP_003077435.1 254792598 8216084 complement(1556307..1556543) 1 NC_013008.1 integrase of prophage CP-933X 1556543 8216084 ECSP_1518 Escherichia coli O157:H7 str. TW14359 integrase of prophage CP-933X YP_003077435.1 1556307 R 544404 CDS YP_003077436.1 254792599 8216085 1556647..1557471 1 NC_013008.1 replication protein O of prophage CP-933X 1557471 8216085 ECSP_1519 Escherichia coli O157:H7 str. TW14359 replication protein O of prophage CP-933X YP_003077436.1 1556647 D 544404 CDS YP_003077437.1 254792600 8216086 1557468..1558169 1 NC_013008.1 replication protein P of prophage CP-933X 1558169 8216086 ECSP_1520 Escherichia coli O157:H7 str. TW14359 replication protein P of prophage CP-933X YP_003077437.1 1557468 D 544404 CDS YP_003077438.1 254792601 8216087 1558166..1558468 1 NC_013008.1 ren protein 1558468 8216087 ECSP_1521 Escherichia coli O157:H7 str. TW14359 ren protein YP_003077438.1 1558166 D 544404 CDS YP_003077439.1 254792602 8216088 1558536..1558868 1 NC_013008.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 1558868 emrE 8216088 emrE Escherichia coli O157:H7 str. TW14359 multidrug efflux protein YP_003077439.1 1558536 D 544404 CDS YP_003077440.1 254792603 8216089 1559113..1560240 1 NC_013008.1 hypothetical protein 1560240 8216089 ECSP_1523 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077440.1 1559113 D 544404 CDS YP_003077441.1 254792604 8216090 1561137..1561592 1 NC_013008.1 DLP12 prophage; hypothetical protein 1561592 8216090 ECSP_1524 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077441.1 1561137 D 544404 CDS YP_003077442.1 254792605 8216091 1561755..1562045 1 NC_013008.1 hypothetical protein 1562045 8216091 ECSP_1525 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077442.1 1561755 D 544404 CDS YP_003077443.1 254792606 8216092 1562042..1562404 1 NC_013008.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1562404 rus 8216092 rus Escherichia coli O157:H7 str. TW14359 endodeoxyribonuclease RUS YP_003077443.1 1562042 D 544404 CDS YP_003077444.1 254792607 8216093 1562538..1563227 1 NC_013008.1 antiterminator Q of prophage CP-933X 1563227 8216093 ECSP_1527 Escherichia coli O157:H7 str. TW14359 antiterminator Q of prophage CP-933X YP_003077444.1 1562538 D 544404 CDS YP_003077445.1 254792608 8216094 1563549..1563854 1 NC_013008.1 holin protein of prophage CP-933X 1563854 8216094 ECSP_1528 Escherichia coli O157:H7 str. TW14359 holin protein of prophage CP-933X YP_003077445.1 1563549 D 544404 CDS YP_003077446.1 254792609 8216095 1563841..1564317 1 NC_013008.1 endolysin of prophage CP-933X 1564317 8216095 ECSP_1529 Escherichia coli O157:H7 str. TW14359 endolysin of prophage CP-933X YP_003077446.1 1563841 D 544404 CDS YP_003077447.1 254792610 8216096 1564458..1564775 1 NC_013008.1 endopeptidase of prophage CP-933X 1564775 8216096 ECSP_1530 Escherichia coli O157:H7 str. TW14359 endopeptidase of prophage CP-933X YP_003077447.1 1564458 D 544404 CDS YP_003077448.1 254792611 8216097 complement(1564807..1565100) 1 NC_013008.1 Bor protein of prophage CP-933X 1565100 8216097 ECSP_1531 Escherichia coli O157:H7 str. TW14359 Bor protein of prophage CP-933X YP_003077448.1 1564807 R 544404 CDS YP_003077449.1 254792612 8216098 complement(1565392..1565802) 1 NC_013008.1 envelope protein of prophage CP-933X 1565802 8216098 ECSP_1532 Escherichia coli O157:H7 str. TW14359 envelope protein of prophage CP-933X YP_003077449.1 1565392 R 544404 CDS YP_003077450.1 254792613 8216099 1566088..1566294 1 NC_013008.1 hypothetical protein 1566294 8216099 ECSP_1533 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077450.1 1566088 D 544404 CDS YP_003077451.1 254792614 8216100 complement(1566459..1566653) 1 NC_013008.1 hypothetical protein 1566653 8216100 ECSP_1534 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077451.1 1566459 R 544404 CDS YP_003077452.1 254792615 8216101 1567042..1567587 1 NC_013008.1 DNA packaging protein of prophage CP-933X 1567587 8216101 ECSP_1535 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933X YP_003077452.1 1567042 D 544404 CDS YP_003077453.1 254792616 8216102 1567562..1569487 1 NC_013008.1 DNA packaging protein of prophage CP-933X 1569487 8216102 ECSP_1536 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933X YP_003077453.1 1567562 D 544404 CDS YP_003077454.1 254792617 8216103 1569535..1569690 1 NC_013008.1 head-tail joining protein of prophage CP-933X 1569690 8216103 ECSP_1537 Escherichia coli O157:H7 str. TW14359 head-tail joining protein of prophage CP-933X YP_003077454.1 1569535 D 544404 CDS YP_003077455.1 254792618 8216104 1569687..1571288 1 NC_013008.1 capsid structural protein of prophage CP-933X 1571288 8216104 ECSP_1538 Escherichia coli O157:H7 str. TW14359 capsid structural protein of prophage CP-933X YP_003077455.1 1569687 D 544404 CDS YP_003077456.1 254792619 8216105 1571269..1572588 1 NC_013008.1 capsid protein of prophage CP-933X 1572588 8216105 ECSP_1539 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage CP-933X YP_003077456.1 1571269 D 544404 CDS YP_003077457.1 254792620 8216106 1572986..1574011 1 NC_013008.1 capsid protein of prophage CP-933X 1574011 8216106 ECSP_1540 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage CP-933X YP_003077457.1 1572986 D 544404 CDS YP_003077458.1 254792621 8216107 1574014..1574451 1 NC_013008.1 DNA packaging protein of prophage CP-933X 1574451 8216107 ECSP_1541 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933X YP_003077458.1 1574014 D 544404 CDS YP_003077459.1 254792622 8216108 1574463..1574816 1 NC_013008.1 head-tail joining protein of prophage CP-933X 1574816 8216108 ECSP_1542 Escherichia coli O157:H7 str. TW14359 head-tail joining protein of prophage CP-933X YP_003077459.1 1574463 D 544404 CDS YP_003077460.1 254792623 8216109 1575161..1575406 1 NC_013008.1 tail component of prophage CP-933X 1575406 8216109 ECSP_1543 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933X YP_003077460.1 1575161 D 544404 CDS YP_003077461.1 254792624 8216110 1575403..1575798 1 NC_013008.1 tail component of prophage CP-933X 1575798 8216110 ECSP_1544 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933X YP_003077461.1 1575403 D 544404 CDS YP_003077462.1 254792625 8216111 1575806..1576546 1 NC_013008.1 tail component of prophage CP-933X 1576546 8216111 ECSP_1545 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933X YP_003077462.1 1575806 D 544404 CDS YP_003077463.1 254792626 8216112 1576562..1576984 1 NC_013008.1 tail component of prophage CP-933X 1576984 8216112 ECSP_1546 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933X YP_003077463.1 1576562 D 544404 CDS YP_003077464.1 254792627 8216113 1576966..1577400 1 NC_013008.1 tail component of prophage CP-933X 1577400 8216113 ECSP_1547 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933X YP_003077464.1 1576966 D 544404 CDS YP_003077465.1 254792628 8216114 1577393..1579942 1 NC_013008.1 tail component of prophage CP-933X 1579942 8216114 ECSP_1548 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933X YP_003077465.1 1577393 D 544404 CDS YP_003077466.1 254792629 8216115 1579939..1580268 1 NC_013008.1 minor tail protein 1580268 8216115 ECSP_1549 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077466.1 1579939 D 544404 CDS YP_003077467.1 254792630 8216116 1580268..1580966 1 NC_013008.1 phage minor tail protein L 1580966 8216116 ECSP_1550 Escherichia coli O157:H7 str. TW14359 phage minor tail protein L YP_003077467.1 1580268 D 544404 CDS YP_003077468.1 254792631 8216117 1580972..1581715 1 NC_013008.1 tail assembly protein 1581715 8216117 ECSP_1551 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003077468.1 1580972 D 544404 CDS YP_003077469.1 254792632 8216118 1581712..1582284 1 NC_013008.1 tail assembly protein I 1582284 8216118 ECSP_1552 Escherichia coli O157:H7 str. TW14359 tail assembly protein I YP_003077469.1 1581712 D 544404 CDS YP_003077470.1 254792633 8216119 1582345..1585743 1 NC_013008.1 host specificity protein J 1585743 8216119 ECSP_1553 Escherichia coli O157:H7 str. TW14359 host specificity protein J YP_003077470.1 1582345 D 544404 CDS YP_003077471.1 254792634 8216120 1585810..1586409 1 NC_013008.1 Ail/Lom family protein 1586409 8216120 ECSP_1554 Escherichia coli O157:H7 str. TW14359 Ail/Lom family protein YP_003077471.1 1585810 D 544404 CDS YP_003077472.1 254792635 8216121 1586474..1589389 1 NC_013008.1 membrane protein of prophage CP-933X 1589389 8216121 ECSP_1555 Escherichia coli O157:H7 str. TW14359 membrane protein of prophage CP-933X YP_003077472.1 1586474 D 544404 CDS YP_003077473.1 254792636 8216122 1589389..1589970 1 NC_013008.1 tail fiber protein of prophage CP-933X 1589970 8216122 ECSP_1556 Escherichia coli O157:H7 str. TW14359 tail fiber protein of prophage CP-933X YP_003077473.1 1589389 D 544404 CDS YP_003077474.1 254792637 8216123 complement(1590090..1590980) 1 NC_013008.1 hypothetical protein 1590980 8216123 ECSP_1557 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077474.1 1590090 R 544404 CDS YP_003077475.1 254792638 8216124 complement(1590999..1591505) 1 NC_013008.1 hypothetical protein 1591505 8216124 ECSP_1558 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077475.1 1590999 R 544404 CDS YP_003077476.1 254792639 8216125 complement(1591542..1592042) 1 NC_013008.1 hypothetical protein 1592042 8216125 ECSP_1559 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077476.1 1591542 R 544404 CDS YP_003077477.1 254792640 8216126 complement(1592121..1592303) 1 NC_013008.1 hypothetical protein 1592303 8216126 ECSP_1560 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077477.1 1592121 R 544404 CDS YP_003077478.1 254792641 8216127 complement(1592801..1593457) 1 NC_013008.1 hypothetical protein 1593457 8216127 ECSP_1561 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077478.1 1592801 R 544404 CDS YP_003077479.1 254792642 8216128 1593526..1593774 1 NC_013008.1 hypothetical protein 1593774 8216128 ECSP_1562 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077479.1 1593526 D 544404 CDS YP_003077480.1 254792643 8216129 1593829..1594230 1 NC_013008.1 hypothetical protein 1594230 8216129 ECSP_1563 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077480.1 1593829 D 544404 CDS YP_003077481.1 254792644 8216130 1594227..1594574 1 NC_013008.1 transposase 1594574 8216130 ECSP_1564 Escherichia coli O157:H7 str. TW14359 transposase YP_003077481.1 1594227 D 544404 CDS YP_003077482.1 254792645 8216131 1594624..1596162 1 NC_013008.1 transposase 1596162 8216131 ECSP_1565 Escherichia coli O157:H7 str. TW14359 transposase YP_003077482.1 1594624 D 544404 CDS YP_003077483.1 254792646 8216132 complement(1596465..1597949) 1 NC_013008.1 protease encoded within prophage CP-933X 1597949 8216132 ECSP_1566 Escherichia coli O157:H7 str. TW14359 protease encoded within prophage CP-933X YP_003077483.1 1596465 R 544404 CDS YP_003077484.1 254792647 8216133 complement(1598136..1599089) 1 NC_013008.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 1599089 ompT 8216133 ompT Escherichia coli O157:H7 str. TW14359 outer membrane protease YP_003077484.1 1598136 R 544404 CDS YP_003077485.1 254792648 8216134 1599224..1599352 1 NC_013008.1 hypothetical protein 1599352 8216134 ECSP_1568 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077485.1 1599224 D 544404 CDS YP_003077486.1 254792649 8216135 1599570..1600172 1 NC_013008.1 hypothetical protein 1600172 8216135 ECSP_1569 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077486.1 1599570 D 544404 CDS YP_003077487.1 254792650 8216136 1600827..1601039 1 NC_013008.1 hypothetical protein 1601039 8216136 ECSP_1570 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077487.1 1600827 D 544404 CDS YP_003077488.1 254792651 8216137 complement(1601411..1601677) 1 NC_013008.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1601677 minE 8216137 minE Escherichia coli O157:H7 str. TW14359 cell division topological specificity factor MinE YP_003077488.1 1601411 R 544404 CDS YP_003077489.1 254792652 8216138 complement(1601681..1602493) 1 NC_013008.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1602493 minD 8216138 minD Escherichia coli O157:H7 str. TW14359 cell division inhibitor MinD YP_003077489.1 1601681 R 544404 CDS YP_003077490.1 254792653 8216139 complement(1602517..1603212) 1 NC_013008.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1603212 minC 8216139 minC Escherichia coli O157:H7 str. TW14359 septum formation inhibitor YP_003077490.1 1602517 R 544404 CDS YP_003077491.1 254792654 8216140 1603732..1604100 1 NC_013008.1 hypothetical protein 1604100 ycgJ 8216140 ycgJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077491.1 1603732 D 544404 CDS YP_003077492.1 254792655 8216141 complement(1604203..1604604) 1 NC_013008.1 hypothetical protein 1604604 ycgK 8216141 ycgK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077492.1 1604203 R 544404 CDS YP_003077493.1 254792656 8216142 1604812..1605138 1 NC_013008.1 hypothetical protein 1605138 ycgL 8216142 ycgL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077493.1 1604812 D 544404 CDS YP_003077494.1 254792657 8216143 1605210..1605869 1 NC_013008.1 hypothetical protein 1605869 ycgM 8216143 ycgM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077494.1 1605210 D 544404 CDS YP_003077495.1 254792658 8216144 1605946..1606407 1 NC_013008.1 hypothetical protein 1606407 ycgN 8216144 ycgN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077495.1 1605946 D 544404 CDS YP_003077496.1 254792659 8216145 complement(1606614..1607525) 1 NC_013008.1 Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E 1607525 hlyE 8216145 hlyE Escherichia coli O157:H7 str. TW14359 hemolysin E YP_003077496.1 1606614 R 544404 CDS YP_003077497.1 254792660 8216146 1607898..1608317 1 NC_013008.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1608317 umuD 8216146 umuD Escherichia coli O157:H7 str. TW14359 DNA polymerase V subunit UmuD YP_003077497.1 1607898 D 544404 CDS YP_003077498.1 254792661 8216147 1608317..1609585 1 NC_013008.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1609585 umuC 8216147 umuC Escherichia coli O157:H7 str. TW14359 DNA polymerase V subunit UmuC YP_003077498.1 1608317 D 544404 CDS YP_003077499.1 254792662 8216148 complement(1609631..1610161) 1 NC_013008.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1610161 dsbB 8216148 dsbB Escherichia coli O157:H7 str. TW14359 disulfide bond formation protein B YP_003077499.1 1609631 R 544404 CDS YP_003077500.1 254792663 8216149 complement(1610307..1611848) 1 NC_013008.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1611848 nhaB 8216149 nhaB Escherichia coli O157:H7 str. TW14359 sodium/proton antiporter YP_003077500.1 1610307 R 544404 CDS YP_003077501.1 254792664 8216150 1612070..1612789 1 NC_013008.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1612789 fadR 8216150 fadR Escherichia coli O157:H7 str. TW14359 fatty acid metabolism regulator YP_003077501.1 1612070 D 544404 CDS YP_003077502.1 254792665 8216151 complement(1612841..1614373) 1 NC_013008.1 SpoVR family protein 1614373 ycgB 8216151 ycgB Escherichia coli O157:H7 str. TW14359 SpoVR family protein YP_003077502.1 1612841 R 544404 CDS YP_003077503.1 254792666 8216152 1614736..1616034 1 NC_013008.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1616034 dadA 8216152 dadA Escherichia coli O157:H7 str. TW14359 D-amino acid dehydrogenase small subunit YP_003077503.1 1614736 D 544404 CDS YP_003077504.1 254792667 8216153 1616044..1617114 1 NC_013008.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1617114 dadX 8216153 dadX Escherichia coli O157:H7 str. TW14359 alanine racemase YP_003077504.1 1616044 D 544404 CDS YP_003077505.1 254792668 8216154 complement(1617503..1619239) 1 NC_013008.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1619239 cvrA 8216154 cvrA Escherichia coli O157:H7 str. TW14359 potassium/proton antiporter YP_003077505.1 1617503 R 544404 CDS YP_003077506.1 254792669 8216155 complement(1619335..1620249) 1 NC_013008.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1620249 ldcA 8216155 ldcA Escherichia coli O157:H7 str. TW14359 L,D-carboxypeptidase A YP_003077506.1 1619335 R 544404 CDS YP_003077507.1 254792670 8216156 1620349..1620960 1 NC_013008.1 lytic murein endotransglycosylase E 1620960 emtA 8216156 emtA Escherichia coli O157:H7 str. TW14359 lytic murein endotransglycosylase E YP_003077507.1 1620349 D 544404 CDS YP_003077508.1 254792671 8216157 complement(1621069..1622229) 1 NC_013008.1 outer membrane autotransporter/adhesion protein 1622229 8216157 ECSP_1591 Escherichia coli O157:H7 str. TW14359 outer membrane autotransporter/adhesion protein YP_003077508.1 1621069 R 544404 CDS YP_003077509.1 254792672 8216158 1622574..1622777 1 NC_013008.1 hypothetical protein 1622777 8216158 ECSP_1592 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077509.1 1622574 D 544404 CDS YP_003077510.1 254792673 8216159 complement(1623073..1624164) 1 NC_013008.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1624164 ychF 8216159 ychF Escherichia coli O157:H7 str. TW14359 GTP-dependent nucleic acid-binding protein EngD YP_003077510.1 1623073 R 544404 CDS YP_003077511.1 254792674 8216160 complement(1624281..1624865) 1 NC_013008.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1624865 pth 8216160 pth Escherichia coli O157:H7 str. TW14359 peptidyl-tRNA hydrolase YP_003077511.1 1624281 R 544404 CDS YP_003077512.1 254792675 8216161 1625143..1625421 1 NC_013008.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1625421 ychH 8216161 ychH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077512.1 1625143 D 544404 CDS YP_003077513.1 254792676 8216162 complement(1625476..1627155) 1 NC_013008.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1627155 ychM 8216162 ychM Escherichia coli O157:H7 str. TW14359 sulfate transporter YchM YP_003077513.1 1625476 R 544404 CDS YP_003077514.1 254792677 8216163 complement(1627280..1628227) 1 NC_013008.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1628227 prsA 8216163 prsA Escherichia coli O157:H7 str. TW14359 ribose-phosphate pyrophosphokinase YP_003077514.1 1627280 R 544404 CDS YP_003077515.1 254792678 8216164 complement(1628378..1629229) 1 NC_013008.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1629229 ipk 8216164 ipk Escherichia coli O157:H7 str. TW14359 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_003077515.1 1628378 R 544404 CDS YP_003077516.1 254792679 8216165 complement(1629229..1629852) 1 NC_013008.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1629852 lolB 8216165 lolB Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein LolB YP_003077516.1 1629229 R 544404 CDS YP_003077517.1 254792680 8216166 1630066..1631322 1 NC_013008.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1631322 hemA 8216166 hemA Escherichia coli O157:H7 str. TW14359 glutamyl-tRNA reductase YP_003077517.1 1630066 D 544404 CDS YP_003077518.1 254792681 8216167 1631364..1632446 1 NC_013008.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1632446 prfA 8216167 prfA Escherichia coli O157:H7 str. TW14359 peptide chain release factor 1 YP_003077518.1 1631364 D 544404 CDS YP_003077519.1 254792682 8216168 1632446..1633279 1 NC_013008.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1633279 prmC 8216168 prmC Escherichia coli O157:H7 str. TW14359 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_003077519.1 1632446 D 544404 CDS YP_003077520.1 254792683 8216169 1633276..1633668 1 NC_013008.1 transcriptional regulator 1633668 ychQ 8216169 ychQ Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003077520.1 1633276 D 544404 CDS YP_003077521.1 254792684 8216170 1633672..1634481 1 NC_013008.1 transcriptional regulator 1634481 ychA 8216170 ychA Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003077521.1 1633672 D 544404 CDS YP_003077522.1 254792685 8216171 1634517..1635371 1 NC_013008.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1635371 kdsA 8216171 kdsA Escherichia coli O157:H7 str. TW14359 2-dehydro-3-deoxyphosphooctonate aldolase YP_003077522.1 1634517 D 544404 CDS YP_003077523.1 254792686 8216172 complement(1635519..1635626) 1 NC_013008.1 toxic polypeptide, small 1635626 ldrA 8216172 ldrA Escherichia coli O157:H7 str. TW14359 toxic polypeptide, small YP_003077523.1 1635519 R 544404 CDS YP_003077524.1 254792687 8216173 complement(1636055..1636162) 1 NC_013008.1 toxic polypeptide, small 1636162 ldrB 8216173 ldrB Escherichia coli O157:H7 str. TW14359 toxic polypeptide, small YP_003077524.1 1636055 R 544404 CDS YP_003077525.1 254792688 8216174 complement(1636561..1637661) 1 NC_013008.1 calcium/sodium:proton antiporter 1637661 chaA 8216174 chaA Escherichia coli O157:H7 str. TW14359 calcium/sodium:proton antiporter YP_003077525.1 1636561 R 544404 CDS YP_003077526.1 254792689 8216175 1637931..1638161 1 NC_013008.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1638161 chaB 8216175 chaB Escherichia coli O157:H7 str. TW14359 cation transport regulator YP_003077526.1 1637931 D 544404 CDS YP_003077527.1 254792690 8216176 1638322..1639017 1 NC_013008.1 regulatory protein for cation transport 1639017 chaC 8216176 chaC Escherichia coli O157:H7 str. TW14359 regulatory protein for cation transport YP_003077527.1 1638322 D 544404 CDS YP_003077528.1 254792691 8216177 complement(1639061..1639414) 1 NC_013008.1 hypothetical protein 1639414 ychN 8216177 ychN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077528.1 1639061 R 544404 CDS YP_003077529.1 254792692 8216178 1639600..1640994 1 NC_013008.1 hypothetical protein 1640994 ychP 8216178 ychP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077529.1 1639600 D 544404 CDS YP_003077530.1 254792693 8216179 complement(1640995..1641645) 1 NC_013008.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1641645 narL 8216179 narL Escherichia coli O157:H7 str. TW14359 transcriptional regulator NarL YP_003077530.1 1640995 R 544404 CDS YP_003077531.1 254792694 8216180 complement(1641638..1643434) 1 NC_013008.1 nitrate/nitrite sensor protein NarX 1643434 narX 8216180 narX Escherichia coli O157:H7 str. TW14359 nitrate/nitrite sensor protein NarX YP_003077531.1 1641638 R 544404 CDS YP_003077532.1 254792695 8216181 1643460..1643678 1 NC_013008.1 hypothetical protein 1643678 8216181 ECSP_1615 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077532.1 1643460 D 544404 CDS YP_003077533.1 254792696 8216182 1643773..1645164 1 NC_013008.1 nitrate/nitrite transporter 1645164 narK 8216182 narK Escherichia coli O157:H7 str. TW14359 nitrate/nitrite transporter YP_003077533.1 1643773 D 544404 CDS YP_003077534.1 254792697 8216183 1645557..1649300 1 NC_013008.1 nitrate reductase 1 subunit alpha 1649300 narG 8216183 narG Escherichia coli O157:H7 str. TW14359 nitrate reductase 1 subunit alpha YP_003077534.1 1645557 D 544404 CDS YP_003077535.1 254792698 8216184 1649297..1650835 1 NC_013008.1 nitrate reductase 1, beta (Fe-S) subunit 1650835 narH 8216184 narH Escherichia coli O157:H7 str. TW14359 nitrate reductase 1, beta (Fe-S) subunit YP_003077535.1 1649297 D 544404 CDS YP_003077536.1 254792699 8216185 1650832..1651542 1 NC_013008.1 nitrate reductase 1 minormolybdenum-cofactor-assembly chaperone 1651542 narJ 8216185 narJ Escherichia coli O157:H7 str. TW14359 nitrate reductase 1 minormolybdenum-cofactor-assembly chaperone YP_003077536.1 1650832 D 544404 CDS YP_003077537.1 254792700 8216186 1651542..1652219 1 NC_013008.1 nitrate reductase 1, gamma (cytochrome b(NR)) subunit 1652219 narI 8216186 narI Escherichia coli O157:H7 str. TW14359 nitrate reductase 1, gamma (cytochrome b(NR)) subunit YP_003077537.1 1651542 D 544404 CDS YP_003077538.1 254792701 8216187 1652402..1652677 1 NC_013008.1 hypothetical protein 1652677 8216187 ECSP_1621 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077538.1 1652402 D 544404 CDS YP_003077539.1 254792702 8216190 complement(1653297..1654139) 1 NC_013008.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1654139 purU 8216190 purU Escherichia coli O157:H7 str. TW14359 formyltetrahydrofolate deformylase YP_003077539.1 1653297 R 544404 CDS YP_003077540.1 254792703 8216191 complement(1654189..1654647) 1 NC_013008.1 hypothetical protein 1654647 ychJ 8216191 ychJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077540.1 1654189 R 544404 CDS YP_003077541.1 254792704 8216192 1654760..1655665 1 NC_013008.1 hypothetical protein 1655665 rssA 8216192 rssA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077541.1 1654760 D 544404 CDS YP_003077542.1 254792705 8216193 1655757..1656770 1 NC_013008.1 response regulator of RpoS 1656770 rssB 8216193 rssB Escherichia coli O157:H7 str. TW14359 response regulator of RpoS YP_003077542.1 1655757 D 544404 CDS YP_003077543.1 254792706 8216194 1656972..1657880 1 NC_013008.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1657880 galU 8216194 galU Escherichia coli O157:H7 str. TW14359 UTP-glucose-1-phosphate uridylyltransferase YP_003077543.1 1656972 D 544404 CDS YP_003077544.1 254792707 8216195 complement(1658024..1658437) 1 NC_013008.1 global DNA-binding transcriptional dual regulator H-NS 1658437 hns 8216195 hns Escherichia coli O157:H7 str. TW14359 global DNA-binding transcriptional dual regulator H-NS YP_003077544.1 1658024 R 544404 CDS YP_003077545.1 254792708 8216196 1659041..1659658 1 NC_013008.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1659658 tdk 8216196 tdk Escherichia coli O157:H7 str. TW14359 thymidine kinase YP_003077545.1 1659041 D 544404 CDS YP_003077546.1 254792709 8216197 complement(1659959..1662634) 1 NC_013008.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1662634 adhE 8216197 adhE Escherichia coli O157:H7 str. TW14359 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_003077546.1 1659959 R 544404 CDS YP_003077547.1 254792710 8216198 1663111..1663758 1 NC_013008.1 hypothetical protein 1663758 ychE 8216198 ychE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077547.1 1663111 D 544404 CDS YP_003077548.1 254792711 8216199 1663785..1663940 1 NC_013008.1 hypothetical protein 1663940 8216199 ECSP_1633 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077548.1 1663785 D 544404 CDS YP_003077549.1 254792712 8216200 complement(1663916..1664077) 1 NC_013008.1 hypothetical protein 1664077 8216200 ECSP_1634 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077549.1 1663916 R 544404 CDS YP_003077550.1 254792713 8216201 1664496..1666127 1 NC_013008.1 oligopeptide ABC transporter periplasmic-binding protein 1666127 oppA 8216201 oppA Escherichia coli O157:H7 str. TW14359 oligopeptide ABC transporter periplasmic-binding protein YP_003077550.1 1664496 D 544404 CDS YP_003077551.1 254792714 8216202 1666213..1667133 1 NC_013008.1 oligopeptide transporter permease 1667133 oppB 8216202 oppB Escherichia coli O157:H7 str. TW14359 oligopeptide transporter permease YP_003077551.1 1666213 D 544404 CDS YP_003077552.1 254792715 8216203 1667148..1668056 1 NC_013008.1 oligopeptide ABC transporter membrane protein 1668056 oppC 8216203 oppC Escherichia coli O157:H7 str. TW14359 oligopeptide ABC transporter membrane protein YP_003077552.1 1667148 D 544404 CDS YP_003077553.1 254792716 8216204 1668068..1669081 1 NC_013008.1 oligopeptide transporter ATP-binding protein 1669081 oppD 8216204 oppD Escherichia coli O157:H7 str. TW14359 oligopeptide transporter ATP-binding protein YP_003077553.1 1668068 D 544404 CDS YP_003077554.1 254792717 8216205 1669078..1670082 1 NC_013008.1 oligopeptide ABC transporter ATP-binding protein 1670082 oppF 8216205 oppF Escherichia coli O157:H7 str. TW14359 oligopeptide ABC transporter ATP-binding protein YP_003077554.1 1669078 D 544404 CDS YP_003077555.1 254792718 8216206 complement(1670135..1670464) 1 NC_013008.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1670464 yciU 8216206 yciU Escherichia coli O157:H7 str. TW14359 dsDNA-mimic protein YP_003077555.1 1670135 R 544404 CDS YP_003077556.1 254792719 8216207 complement(1670499..1671959) 1 NC_013008.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1671959 cls 8216207 cls Escherichia coli O157:H7 str. TW14359 cardiolipin synthetase YP_003077556.1 1670499 R 544404 CDS YP_003077557.1 254792720 8216208 complement(1672330..1673583) 1 NC_013008.1 voltage-gated potassium channel 1673583 kch 8216208 kch Escherichia coli O157:H7 str. TW14359 voltage-gated potassium channel YP_003077557.1 1672330 R 544404 CDS YP_003077558.1 254792721 8216209 complement(1673884..1674180) 1 NC_013008.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1674180 yciI 8216209 yciI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077558.1 1673884 R 544404 CDS YP_003077559.1 254792722 8216210 1674404..1675123 1 NC_013008.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1675123 tonB 8216210 tonB Escherichia coli O157:H7 str. TW14359 transport protein TonB YP_003077559.1 1674404 D 544404 CDS YP_003077560.1 254792723 8216211 complement(1675163..1675561) 1 NC_013008.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1675561 yciA 8216211 yciA Escherichia coli O157:H7 str. TW14359 acyl-CoA thioester hydrolase YP_003077560.1 1675163 R 544404 CDS YP_003077561.1 254792724 8216212 complement(1675666..1676205) 1 NC_013008.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1676205 yciB 8216212 yciB Escherichia coli O157:H7 str. TW14359 intracellular septation protein A YP_003077561.1 1675666 R 544404 CDS YP_003077562.1 254792725 8216213 complement(1676235..1676978) 1 NC_013008.1 hypothetical protein 1676978 yciC 8216213 yciC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077562.1 1676235 R 544404 CDS YP_003077563.1 254792726 8216214 1677335..1677973 1 NC_013008.1 receptor for colicin S4; outer membrane protein W 1677973 ompW 8216214 ompW Escherichia coli O157:H7 str. TW14359 outer membrane protein W YP_003077563.1 1677335 D 544404 CDS YP_003077564.1 254792727 8216215 complement(1678019..1679149) 1 NC_013008.1 integrase for prophage CP-933O 1679149 intO 8216215 intO Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933O YP_003077564.1 1678019 R 544404 CDS YP_003077565.1 254792728 8216216 complement(1679440..1681911) 1 NC_013008.1 exonuclease VIII, ds DNA exonuclease, 5' --> 3' specific encoded by prophage CP-933O 1681911 exoO 8216216 exoO Escherichia coli O157:H7 str. TW14359 exonuclease VIII, ds DNA exonuclease, 5' --> 3' specific encoded by prophage CP-933O YP_003077565.1 1679440 R 544404 CDS YP_003077566.1 254792729 8216217 1682939..1683172 1 NC_013008.1 hypothetical protein 1683172 8216217 ECSP_1651 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077566.1 1682939 D 544404 CDS YP_003077567.1 254792730 8216218 complement(1683150..1683557) 1 NC_013008.1 hypothetical protein 1683557 8216218 ECSP_1652 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077567.1 1683150 R 544404 CDS YP_003077568.1 254792731 8216219 complement(1683580..1683798) 1 NC_013008.1 hypothetical protein 1683798 8216219 ECSP_1653 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077568.1 1683580 R 544404 CDS YP_003077569.1 254792732 8216220 complement(1683871..1684170) 1 NC_013008.1 hypothetical protein 1684170 8216220 ECSP_1654 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077569.1 1683871 R 544404 CDS YP_003077570.1 254792733 8216221 complement(1684434..1684841) 1 NC_013008.1 encoded by prophage CP-933O; The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown; transcriptional repressor DicA 1684841 8216221 ECSP_1655 Escherichia coli O157:H7 str. TW14359 transcriptional repressor DicA YP_003077570.1 1684434 R 544404 CDS YP_003077571.1 254792734 8216222 1684918..1685145 1 NC_013008.1 DNA-binding transcriptional regulator DicC 1685145 8216222 ECSP_1656 Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator DicC YP_003077571.1 1684918 D 544404 CDS YP_003077572.1 254792735 8216223 1685129..1685680 1 NC_013008.1 hypothetical protein 1685680 8216223 ECSP_1657 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077572.1 1685129 D 544404 CDS YP_003077573.1 254792736 8216224 1685652..1686692 1 NC_013008.1 hypothetical protein 1686692 8216224 ECSP_1658 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077573.1 1685652 D 544404 CDS YP_003077574.1 254792737 8216225 1686724..1687146 1 NC_013008.1 hypothetical protein 1687146 8216225 ECSP_1659 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077574.1 1686724 D 544404 CDS YP_003077575.1 254792738 8216226 1687333..1687914 1 NC_013008.1 hypothetical protein 1687914 8216226 ECSP_1660 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077575.1 1687333 D 544404 CDS YP_003077576.1 254792739 8216227 1687950..1688075 1 NC_013008.1 hypothetical protein 1688075 8216227 ECSP_1661 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077576.1 1687950 D 544404 CDS YP_003077577.1 254792740 8216229 1688786..1689532 1 NC_013008.1 colonization factor 1689532 8216229 ECSP_1663 Escherichia coli O157:H7 str. TW14359 colonization factor YP_003077577.1 1688786 D 544404 CDS YP_003077578.1 254792741 8216230 1689811..1690023 1 NC_013008.1 killer protein encoded by prophage CP-933O 1690023 8216230 ECSP_1664 Escherichia coli O157:H7 str. TW14359 killer protein encoded by prophage CP-933O YP_003077578.1 1689811 D 544404 CDS YP_003077579.1 254792742 8216231 1690244..1690501 1 NC_013008.1 hypothetical protein 1690501 8216231 ECSP_1665 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077579.1 1690244 D 544404 CDS YP_003077580.1 254792743 8216232 1690571..1690849 1 NC_013008.1 hypothetical protein 1690849 8216232 ECSP_1666 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077580.1 1690571 D 544404 CDS YP_003077581.1 254792744 8216233 1690851..1691897 1 NC_013008.1 hypothetical protein 1691897 8216233 ECSP_1667 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077581.1 1690851 D 544404 CDS YP_003077582.1 254792745 8216234 1691910..1692269 1 NC_013008.1 endonuclease of prophage CP-933O 1692269 8216234 ECSP_1668 Escherichia coli O157:H7 str. TW14359 endonuclease of prophage CP-933O YP_003077582.1 1691910 D 544404 CDS YP_003077583.1 254792746 8216235 1692278..1692808 1 NC_013008.1 hypothetical protein 1692808 8216235 ECSP_1669 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077583.1 1692278 D 544404 CDS YP_003077584.1 254792747 8216236 1692927..1693247 1 NC_013008.1 hypothetical protein 1693247 8216236 ECSP_1670 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077584.1 1692927 D 544404 CDS YP_003077585.1 254792748 8216237 1693398..1694456 1 NC_013008.1 DNA adenine methyltransferase encoded by prophage CP-933O 1694456 8216237 ECSP_1671 Escherichia coli O157:H7 str. TW14359 DNA adenine methyltransferase encoded by prophage CP-933O YP_003077585.1 1693398 D 544404 CDS YP_003077586.1 254792749 8216240 1695534..1696073 1 NC_013008.1 hypothetical protein 1696073 8216240 ECSP_1674 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077586.1 1695534 D 544404 CDS YP_003077587.1 254792750 8216241 1696124..1696438 1 NC_013008.1 holin protein 1696438 8216241 ECSP_1675 Escherichia coli O157:H7 str. TW14359 holin protein YP_003077587.1 1696124 D 544404 CDS YP_003077588.1 254792751 8216242 1696440..1696787 1 NC_013008.1 hypothetical protein 1696787 8216242 ECSP_1676 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077588.1 1696440 D 544404 CDS YP_003077589.1 254792752 8216243 1696838..1697371 1 NC_013008.1 endolysin encoded by cryptic prophage CP-933P 1697371 8216243 ECSP_1677 Escherichia coli O157:H7 str. TW14359 endolysin encoded by cryptic prophage CP-933P YP_003077589.1 1696838 D 544404 CDS YP_003077590.1 254792753 8216244 1697642..1698211 1 NC_013008.1 antirepressor protein encoded by cryptic prophage CP-933 1698211 8216244 ECSP_1678 Escherichia coli O157:H7 str. TW14359 antirepressor protein encoded by cryptic prophage CP-933 YP_003077590.1 1697642 D 544404 CDS YP_003077591.1 254792754 8216245 1698365..1698832 1 NC_013008.1 endopeptidase of prophage CP-933 1698832 8216245 ECSP_1679 Escherichia coli O157:H7 str. TW14359 endopeptidase of prophage CP-933 YP_003077591.1 1698365 D 544404 CDS YP_003077592.1 254792755 8216246 1700303..1700848 1 NC_013008.1 DNA packaging protein of prophage CP-933X 1700848 8216246 ECSP_1680 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933X YP_003077592.1 1700303 D 544404 CDS YP_003077593.1 254792756 8216247 1701003..1702748 1 NC_013008.1 DNA packaging protein of prophage CP-933X 1702748 8216247 ECSP_1681 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933X YP_003077593.1 1701003 D 544404 CDS YP_003077594.1 254792757 8216248 1702948..1704549 1 NC_013008.1 capsid structural protein of prophage CP-933X 1704549 8216248 ECSP_1682 Escherichia coli O157:H7 str. TW14359 capsid structural protein of prophage CP-933X YP_003077594.1 1702948 D 544404 CDS YP_003077595.1 254792758 8216249 1704530..1705849 1 NC_013008.1 capsid protein of prophage CP-933X 1705849 8216249 ECSP_1683 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage CP-933X YP_003077595.1 1704530 D 544404 CDS YP_003077596.1 254792759 8216250 1706247..1707272 1 NC_013008.1 capsid protein of prophage CP-933X 1707272 8216250 ECSP_1684 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage CP-933X YP_003077596.1 1706247 D 544404 CDS YP_003077597.1 254792760 8216251 1707275..1707712 1 NC_013008.1 DNA packaging protein of prophage CP-933X 1707712 8216251 ECSP_1685 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933X YP_003077597.1 1707275 D 544404 CDS YP_003077598.1 254792761 8216252 1707724..1708077 1 NC_013008.1 head-tail joining protein of prophage CP-933X 1708077 8216252 ECSP_1686 Escherichia coli O157:H7 str. TW14359 head-tail joining protein of prophage CP-933X YP_003077598.1 1707724 D 544404 CDS YP_003077599.1 254792762 8216253 1708092..1708625 1 NC_013008.1 hypothetical protein 1708625 8216253 ECSP_1687 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077599.1 1708092 D 544404 CDS YP_003077600.1 254792763 8216254 1708622..1709017 1 NC_013008.1 tail fiber component U of prophage CP-933U 1709017 8216254 ECSP_1688 Escherichia coli O157:H7 str. TW14359 tail fiber component U of prophage CP-933U YP_003077600.1 1708622 D 544404 CDS YP_003077601.1 254792764 8216255 1709025..1709777 1 NC_013008.1 tail fiber component V of prophage CP-933U 1709777 8216255 ECSP_1689 Escherichia coli O157:H7 str. TW14359 tail fiber component V of prophage CP-933U YP_003077601.1 1709025 D 544404 CDS YP_003077602.1 254792765 8216256 1709791..1710213 1 NC_013008.1 tail fiber component G of prophage CP-933U 1710213 8216256 ECSP_1690 Escherichia coli O157:H7 str. TW14359 tail fiber component G of prophage CP-933U YP_003077602.1 1709791 D 544404 CDS YP_003077603.1 254792766 8216257 1710240..1710548 1 NC_013008.1 tail fiber component T of prophage CP-933U 1710548 8216257 ECSP_1691 Escherichia coli O157:H7 str. TW14359 tail fiber component T of prophage CP-933U YP_003077603.1 1710240 D 544404 CDS YP_003077604.1 254792767 8216258 1710592..1713237 1 NC_013008.1 tail fiber component H of prophage CP-933U 1713237 8216258 ECSP_1692 Escherichia coli O157:H7 str. TW14359 tail fiber component H of prophage CP-933U YP_003077604.1 1710592 D 544404 CDS YP_003077605.1 254792768 8216259 1713234..1713563 1 NC_013008.1 tail component of prophage CP-933O 1713563 8216259 ECSP_1693 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933O YP_003077605.1 1713234 D 544404 CDS YP_003077606.1 254792769 8216260 1713563..1714261 1 NC_013008.1 tail component of prophage CP-933O 1714261 8216260 ECSP_1694 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933O YP_003077606.1 1713563 D 544404 CDS YP_003077607.1 254792770 8216261 1714380..1715015 1 NC_013008.1 tail component of prophage CP-933O 1715015 8216261 ECSP_1695 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933O YP_003077607.1 1714380 D 544404 CDS YP_003077608.1 254792771 8216262 1715012..1715590 1 NC_013008.1 tail assembly protein of cryptic prophage CP-933P 1715590 8216262 ECSP_1696 Escherichia coli O157:H7 str. TW14359 tail assembly protein of cryptic prophage CP-933P YP_003077608.1 1715012 D 544404 CDS YP_003077609.1 254792772 8216263 1715831..1718686 1 NC_013008.1 tail component of cryptic prophage CP-933P 1718686 8216263 ECSP_1697 Escherichia coli O157:H7 str. TW14359 tail component of cryptic prophage CP-933P YP_003077609.1 1715831 D 544404 CDS YP_003077610.1 254792773 8216264 1718754..1719353 1 NC_013008.1 Lom-like outer membrane protein of cryptic prophage CP-933P 1719353 lomP 8216264 lomP Escherichia coli O157:H7 str. TW14359 Lom-like outer membrane protein of cryptic prophage CP-933P YP_003077610.1 1718754 D 544404 CDS YP_003077611.1 254792774 8216265 1719505..1720809 1 NC_013008.1 tail fiber protein of cryptic prophage CP-933P 1720809 8216265 ECSP_1699 Escherichia coli O157:H7 str. TW14359 tail fiber protein of cryptic prophage CP-933P YP_003077611.1 1719505 D 544404 CDS YP_003077612.1 254792775 8216266 1720811..1721080 1 NC_013008.1 hypothetical protein 1721080 8216266 ECSP_1700 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077612.1 1720811 D 544404 CDS YP_003077613.1 254792776 8216267 1721237..1721767 1 NC_013008.1 hypothetical protein 1721767 8216267 ECSP_1701 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077613.1 1721237 D 544404 CDS YP_003077614.1 254792777 8216268 complement(1722107..1723432) 1 NC_013008.1 non-LEE-encoded type III effector 1723432 nleA 8216268 nleA Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077614.1 1722107 R 544404 CDS YP_003077615.1 254792778 8216269 complement(1724093..1724785) 1 NC_013008.1 integrase 1724785 8216269 ECSP_1703 Escherichia coli O157:H7 str. TW14359 integrase YP_003077615.1 1724093 R 544404 CDS YP_003077616.1 254792779 8216270 1725259..1726170 1 NC_013008.1 non-LEE-encoded type III effector 1726170 nleH2 8216270 nleH2 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077616.1 1725259 D 544404 CDS YP_003077617.1 254792780 8216271 1726236..1726805 1 NC_013008.1 non-LEE-encoded type III effector 1726805 nleF 8216271 nleF Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077617.1 1726236 D 544404 CDS YP_003077618.1 254792781 8216273 complement(1727771..1729309) 1 NC_013008.1 transposase ISEc8 1729309 8216273 ECSP_1707 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003077618.1 1727771 R 544404 CDS YP_003077619.1 254792782 8216274 complement(1729359..1729706) 1 NC_013008.1 transposase 1729706 8216274 ECSP_1708 Escherichia coli O157:H7 str. TW14359 transposase YP_003077619.1 1729359 R 544404 CDS YP_003077620.1 254792783 8216275 complement(1729703..1730104) 1 NC_013008.1 transposase 1730104 8216275 ECSP_1709 Escherichia coli O157:H7 str. TW14359 transposase YP_003077620.1 1729703 R 544404 CDS YP_003077621.1 254792784 8216276 complement(1730423..1730701) 1 NC_013008.1 non-LEE-encoded type III effector 1730701 8216276 ECSP_1710 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077621.1 1730423 R 544404 CDS YP_003077622.1 254792785 8216277 complement(1731412..1732059) 1 NC_013008.1 non-LEE-encoded type III effector 1732059 8216277 ECSP_1711 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077622.1 1731412 R 544404 CDS YP_003077623.1 254792786 8216278 1732243..1732833 1 NC_013008.1 non-LEE-encoded type III effector 1732833 espM1 8216278 espM1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077623.1 1732243 D 544404 CDS YP_003077624.1 254792787 8216282 complement(1736291..1737421) 1 NC_013008.1 integrase for prophage CP-933O 1737421 8216282 ECSP_1716 Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933O YP_003077624.1 1736291 R 544404 CDS YP_003077625.1 254792788 8216283 complement(1737712..1740156) 1 NC_013008.1 exodeoxyribonuclease VIII 1740156 8216283 ECSP_1717 Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease VIII YP_003077625.1 1737712 R 544404 CDS YP_003077626.1 254792789 8216284 complement(1740249..1740377) 1 NC_013008.1 hypothetical protein 1740377 8216284 ECSP_1718 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077626.1 1740249 R 544404 CDS YP_003077627.1 254792790 8216285 1740531..1740722 1 NC_013008.1 O antigen biosynthesis protein 1740722 8216285 ECSP_1719 Escherichia coli O157:H7 str. TW14359 O antigen biosynthesis protein YP_003077627.1 1740531 D 544404 CDS YP_003077628.1 254792791 8216286 1740849..1741184 1 NC_013008.1 hypothetical protein 1741184 8216286 ECSP_1720 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077628.1 1740849 D 544404 CDS YP_003077629.1 254792792 8216287 complement(1741188..1741406) 1 NC_013008.1 hypothetical protein 1741406 8216287 ECSP_1721 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077629.1 1741188 R 544404 CDS YP_003077630.1 254792793 8216288 complement(1741436..1741564) 1 NC_013008.1 hypothetical protein 1741564 8216288 ECSP_1722 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077630.1 1741436 R 544404 CDS YP_003077631.1 254792794 8216289 complement(1741566..1741721) 1 NC_013008.1 hypothetical protein 1741721 8216289 ECSP_1723 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077631.1 1741566 R 544404 CDS YP_003077632.1 254792795 8216290 complement(1741911..1742318) 1 NC_013008.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1742318 8216290 ECSP_1724 Escherichia coli O157:H7 str. TW14359 transcriptional repressor DicA YP_003077632.1 1741911 R 544404 CDS YP_003077633.1 254792796 8216291 1742667..1743158 1 NC_013008.1 hypothetical protein 1743158 8216291 ECSP_1725 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077633.1 1742667 D 544404 CDS YP_003077634.1 254792797 8216292 1743130..1744170 1 NC_013008.1 hypothetical protein 1744170 8216292 ECSP_1726 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077634.1 1743130 D 544404 CDS YP_003077635.1 254792798 8216293 1744163..1744624 1 NC_013008.1 hypothetical protein 1744624 8216293 ECSP_1727 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077635.1 1744163 D 544404 CDS YP_003077636.1 254792799 8216294 1744659..1745429 1 NC_013008.1 hypothetical protein 1745429 8216294 ECSP_1728 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077636.1 1744659 D 544404 CDS YP_003077637.1 254792800 8216295 1745445..1745840 1 NC_013008.1 hypothetical protein 1745840 8216295 ECSP_1729 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077637.1 1745445 D 544404 CDS YP_003077638.1 254792801 8216296 1745897..1746253 1 NC_013008.1 hypothetical protein 1746253 8216296 ECSP_1730 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077638.1 1745897 D 544404 CDS YP_003077639.1 254792802 8216297 1746302..1746514 1 NC_013008.1 hypothetical protein 1746514 8216297 ECSP_1731 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077639.1 1746302 D 544404 CDS YP_003077640.1 254792803 8216298 1746550..1746921 1 NC_013008.1 hypothetical protein 1746921 8216298 ECSP_1732 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077640.1 1746550 D 544404 CDS YP_003077641.1 254792804 8216299 1746918..1747280 1 NC_013008.1 hypothetical protein 1747280 8216299 ECSP_1733 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077641.1 1746918 D 544404 CDS YP_003077642.1 254792805 8216300 1747351..1747500 1 NC_013008.1 hypothetical protein 1747500 8216300 ECSP_1734 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077642.1 1747351 D 544404 CDS YP_003077643.1 254792806 8216301 1748122..1748379 1 NC_013008.1 hypothetical protein 1748379 8216301 ECSP_1735 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077643.1 1748122 D 544404 CDS YP_003077644.1 254792807 8216302 1748449..1748727 1 NC_013008.1 hypothetical protein 1748727 8216302 ECSP_1736 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077644.1 1748449 D 544404 CDS YP_003077645.1 254792808 8216303 1748729..1749778 1 NC_013008.1 hypothetical protein 1749778 8216303 ECSP_1737 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077645.1 1748729 D 544404 CDS YP_003077646.1 254792809 8216304 1749791..1750165 1 NC_013008.1 endodeoxyribonuclease RusA 1750165 8216304 ECSP_1738 Escherichia coli O157:H7 str. TW14359 endodeoxyribonuclease RusA YP_003077646.1 1749791 D 544404 CDS YP_003077647.1 254792810 8216305 1750162..1750983 1 NC_013008.1 antitermination protein Q-like protein of cryptic prophage CP-933M 1750983 8216305 ECSP_1739 Escherichia coli O157:H7 str. TW14359 antitermination protein Q-like protein of cryptic prophage CP-933M YP_003077647.1 1750162 D 544404 CDS YP_003077648.1 254792811 8216306 1751210..1751407 1 NC_013008.1 hypothetical protein 1751407 8216306 ECSP_1740 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077648.1 1751210 D 544404 CDS YP_003077649.1 254792812 8216307 1751429..1751530 1 NC_013008.1 hypothetical protein 1751530 8216307 ECSP_1741 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077649.1 1751429 D 544404 CDS YP_003077650.1 254792813 8216308 1751558..1752616 1 NC_013008.1 DNA methylase 1752616 8216308 ECSP_1742 Escherichia coli O157:H7 str. TW14359 DNA methylase YP_003077650.1 1751558 D 544404 CDS YP_003077651.1 254792814 8216310 complement(1752824..1752970) 1 NC_013008.1 hypothetical protein 1752970 8216310 ECSP_1744 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077651.1 1752824 R 544404 CDS YP_003077652.1 254792815 8216311 1753211..1755157 1 NC_013008.1 hypothetical protein 1755157 8216311 ECSP_1745 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077652.1 1753211 D 544404 CDS YP_003077653.1 254792816 8216312 1755338..1755757 1 NC_013008.1 hypothetical protein 1755757 8216312 ECSP_1746 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077653.1 1755338 D 544404 CDS YP_003077654.1 254792817 8216313 1755760..1756050 1 NC_013008.1 lysis protein 1756050 8216313 ECSP_1747 Escherichia coli O157:H7 str. TW14359 lysis protein YP_003077654.1 1755760 D 544404 CDS YP_003077655.1 254792818 8216314 1756054..1756611 1 NC_013008.1 hypothetical protein 1756611 8216314 ECSP_1748 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077655.1 1756054 D 544404 CDS YP_003077656.1 254792819 8216315 1756648..1757181 1 NC_013008.1 endolysin 1757181 8216315 ECSP_1749 Escherichia coli O157:H7 str. TW14359 endolysin YP_003077656.1 1756648 D 544404 CDS YP_003077657.1 254792820 8216316 1757480..1757947 1 NC_013008.1 bacteriophage lysis protein 1757947 8216316 ECSP_1750 Escherichia coli O157:H7 str. TW14359 bacteriophage lysis protein YP_003077657.1 1757480 D 544404 CDS YP_003077658.1 254792821 8216317 1758360..1758836 1 NC_013008.1 hypothetical protein 1758836 8216317 ECSP_1751 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077658.1 1758360 D 544404 CDS YP_003077659.1 254792822 8216318 1758833..1760956 1 NC_013008.1 terminase large subunit 1760956 8216318 ECSP_1752 Escherichia coli O157:H7 str. TW14359 terminase large subunit YP_003077659.1 1758833 D 544404 CDS YP_003077660.1 254792823 8216319 1761165..1762667 1 NC_013008.1 phage portal protein, lambda family 1762667 8216319 ECSP_1753 Escherichia coli O157:H7 str. TW14359 phage portal protein, lambda family YP_003077660.1 1761165 D 544404 CDS YP_003077661.1 254792824 8216320 1762681..1764636 1 NC_013008.1 protease 1764636 8216320 ECSP_1754 Escherichia coli O157:H7 str. TW14359 protease YP_003077661.1 1762681 D 544404 CDS YP_003077662.1 254792825 8216321 1764724..1765050 1 NC_013008.1 hypothetical protein 1765050 8216321 ECSP_1755 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077662.1 1764724 D 544404 CDS YP_003077663.1 254792826 8216322 1765076..1765324 1 NC_013008.1 hypothetical protein 1765324 8216322 ECSP_1756 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077663.1 1765076 D 544404 CDS YP_003077664.1 254792827 8216323 1765327..1765950 1 NC_013008.1 prophage minor tail protein Z 1765950 8216323 ECSP_1757 Escherichia coli O157:H7 str. TW14359 prophage minor tail protein Z YP_003077664.1 1765327 D 544404 CDS YP_003077665.1 254792828 8216324 1765963..1766361 1 NC_013008.1 phage minor tail protein U 1766361 8216324 ECSP_1758 Escherichia coli O157:H7 str. TW14359 phage minor tail protein U YP_003077665.1 1765963 D 544404 CDS YP_003077666.1 254792829 8216325 1766369..1767121 1 NC_013008.1 tail fiber component 1767121 8216325 ECSP_1759 Escherichia coli O157:H7 str. TW14359 tail fiber component YP_003077666.1 1766369 D 544404 CDS YP_003077667.1 254792830 8216326 1767135..1767557 1 NC_013008.1 minor tail protein 1767557 8216326 ECSP_1760 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077667.1 1767135 D 544404 CDS YP_003077668.1 254792831 8216327 1767608..1767892 1 NC_013008.1 tail assembly protein T 1767892 8216327 ECSP_1761 Escherichia coli O157:H7 str. TW14359 tail assembly protein T YP_003077668.1 1767608 D 544404 CDS YP_003077669.1 254792832 8216328 1767936..1770581 1 NC_013008.1 tail fiber component H 1770581 8216328 ECSP_1762 Escherichia coli O157:H7 str. TW14359 tail fiber component H YP_003077669.1 1767936 D 544404 CDS YP_003077670.1 254792833 8216329 1770578..1770907 1 NC_013008.1 phage minor tail protein 1770907 8216329 ECSP_1763 Escherichia coli O157:H7 str. TW14359 phage minor tail protein YP_003077670.1 1770578 D 544404 CDS YP_003077671.1 254792834 8216330 1770907..1771605 1 NC_013008.1 tail fiber component L 1771605 8216330 ECSP_1764 Escherichia coli O157:H7 str. TW14359 tail fiber component L YP_003077671.1 1770907 D 544404 CDS YP_003077672.1 254792835 8216331 1771724..1772359 1 NC_013008.1 hypothetical protein 1772359 8216331 ECSP_1765 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077672.1 1771724 D 544404 CDS YP_003077673.1 254792836 8216332 1772356..1772934 1 NC_013008.1 tail assembly protein 1772934 8216332 ECSP_1766 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003077673.1 1772356 D 544404 CDS YP_003077674.1 254792837 8216333 1773175..1776651 1 NC_013008.1 host specificity protein J 1776651 8216333 ECSP_1767 Escherichia coli O157:H7 str. TW14359 host specificity protein J YP_003077674.1 1773175 D 544404 CDS YP_003077675.1 254792838 8216334 1776719..1777318 1 NC_013008.1 outer membrane protein Lom 1777318 8216334 ECSP_1768 Escherichia coli O157:H7 str. TW14359 outer membrane protein Lom YP_003077675.1 1776719 D 544404 CDS YP_003077676.1 254792839 8216335 1777383..1778696 1 NC_013008.1 tail fiber protein 1778696 8216335 ECSP_1769 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003077676.1 1777383 D 544404 CDS YP_003077677.1 254792840 8216336 1778698..1778967 1 NC_013008.1 tail fiber protein 1778967 8216336 ECSP_1770 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003077677.1 1778698 D 544404 CDS YP_003077678.1 254792841 8216337 1779227..1779502 1 NC_013008.1 IS1 transposase 1779502 8216337 ECSP_1771 Escherichia coli O157:H7 str. TW14359 IS1 transposase YP_003077678.1 1779227 D 544404 CDS YP_003077679.1 254792842 8216338 1779529..1779924 1 NC_013008.1 IS1 transposase 1779924 8216338 ECSP_1772 Escherichia coli O157:H7 str. TW14359 IS1 transposase YP_003077679.1 1779529 D 544404 CDS YP_003077680.1 254792843 8216339 1780100..1780690 1 NC_013008.1 hypothetical protein 1780690 ospG 8216339 ospG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077680.1 1780100 D 544404 CDS YP_003077681.1 254792844 8216340 1780930..1781238 1 NC_013008.1 hypothetical protein 1781238 8216340 ECSP_1774 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077681.1 1780930 D 544404 CDS YP_003077682.1 254792845 8216341 1781552..1781668 1 NC_013008.1 hypothetical protein 1781668 8216341 ECSP_1775 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077682.1 1781552 D 544404 CDS YP_003077683.1 254792846 8216342 complement(1781728..1782234) 1 NC_013008.1 hypothetical protein 1782234 yciE 8216342 yciE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077683.1 1781728 R 544404 CDS YP_003077684.1 254792847 8216343 complement(1782280..1782780) 1 NC_013008.1 hypothetical protein 1782780 yciF 8216343 yciF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077684.1 1782280 R 544404 CDS YP_003077685.1 254792848 8216344 complement(1782866..1783045) 1 NC_013008.1 hypothetical protein 1783045 8216344 ECSP_1778 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077685.1 1782866 R 544404 CDS YP_003077686.1 254792849 8216345 complement(1783426..1784232) 1 NC_013008.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1784232 trpA 8216345 trpA Escherichia coli O157:H7 str. TW14359 tryptophan synthase subunit alpha YP_003077686.1 1783426 R 544404 CDS YP_003077687.1 254792850 8216346 complement(1784232..1785425) 1 NC_013008.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1785425 trpB 8216346 trpB Escherichia coli O157:H7 str. TW14359 tryptophan synthase subunit beta YP_003077687.1 1784232 R 544404 CDS YP_003077688.1 254792851 8216347 complement(1785437..1786795) 1 NC_013008.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1786795 trpC 8216347 trpC Escherichia coli O157:H7 str. TW14359 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_003077688.1 1785437 R 544404 CDS YP_003077689.1 254792852 8216348 complement(1786799..1788394) 1 NC_013008.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1788394 trpD 8216348 trpD Escherichia coli O157:H7 str. TW14359 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_003077689.1 1786799 R 544404 CDS YP_003077690.1 254792853 8216349 complement(1788394..1789956) 1 NC_013008.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1789956 trpE 8216349 trpE Escherichia coli O157:H7 str. TW14359 anthranilate synthase component I YP_003077690.1 1788394 R 544404 CDS YP_003077691.1 254792854 8216350 1790230..1791111 1 NC_013008.1 hypothetical protein 1791111 yciV 8216350 yciV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077691.1 1790230 D 544404 CDS YP_003077692.1 254792855 8216351 1791108..1791728 1 NC_013008.1 hypothetical protein 1791728 yciO 8216351 yciO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077692.1 1791108 D 544404 CDS YP_003077693.1 254792856 8216352 1791756..1793339 1 NC_013008.1 hypothetical protein 1793339 8216352 ECSP_1786 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077693.1 1791756 D 544404 CDS YP_003077694.1 254792857 8216353 1793552..1794424 1 NC_013008.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1794424 rluB 8216353 rluB Escherichia coli O157:H7 str. TW14359 23S rRNA pseudouridylate synthase B YP_003077694.1 1793552 D 544404 CDS YP_003077695.1 254792858 8216354 complement(1794464..1795054) 1 NC_013008.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1795054 btuR 8216354 btuR Escherichia coli O157:H7 str. TW14359 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_003077695.1 1794464 R 544404 CDS YP_003077696.1 254792859 8216355 complement(1795051..1795809) 1 NC_013008.1 short chain dehydrogenase 1795809 yciK 8216355 yciK Escherichia coli O157:H7 str. TW14359 short chain dehydrogenase YP_003077696.1 1795051 R 544404 CDS YP_003077697.1 254792860 8216356 1796029..1797078 1 NC_013008.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1797078 sohB 8216356 sohB Escherichia coli O157:H7 str. TW14359 periplasmic protease YP_003077697.1 1796029 D 544404 CDS YP_003077698.1 254792861 8216357 complement(1797114..1797365) 1 NC_013008.1 hypothetical protein 1797365 yciN 8216357 yciN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077698.1 1797114 R 544404 CDS YP_003077699.1 254792862 8216358 1797745..1800342 1 NC_013008.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1800342 topA 8216358 topA Escherichia coli O157:H7 str. TW14359 DNA topoisomerase I YP_003077699.1 1797745 D 544404 CDS YP_003077700.1 254792863 8216359 1800552..1801526 1 NC_013008.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1801526 cysB 8216359 cysB Escherichia coli O157:H7 str. TW14359 transcriptional regulator CysB YP_003077700.1 1800552 D 544404 CDS YP_003077701.1 254792864 8216360 1801857..1801985 1 NC_013008.1 hypothetical protein 1801985 8216360 ECSP_1794 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077701.1 1801857 D 544404 CDS YP_003077702.1 254792865 8216361 1801988..1802155 1 NC_013008.1 hypothetical protein 1802155 yciX 8216361 yciX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077702.1 1801988 D 544404 CDS YP_003077703.1 254792866 8216362 1802528..1805203 1 NC_013008.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1805203 acnA 8216362 acnA Escherichia coli O157:H7 str. TW14359 aconitate hydratase YP_003077703.1 1802528 D 544404 CDS YP_003077704.1 254792867 8216363 complement(1805267..1805857) 1 NC_013008.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1805857 ribA 8216363 ribA Escherichia coli O157:H7 str. TW14359 GTP cyclohydrolase II YP_003077704.1 1805267 R 544404 CDS YP_003077705.1 254792868 8216364 1806027..1806791 1 NC_013008.1 phosphatidylglycerophosphatase B 1806791 pgpB 8216364 pgpB Escherichia coli O157:H7 str. TW14359 phosphatidylglycerophosphatase B YP_003077705.1 1806027 D 544404 CDS YP_003077706.1 254792869 8216365 1806940..1807248 1 NC_013008.1 hypothetical protein 1807248 yciS 8216365 yciS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077706.1 1806940 D 544404 CDS YP_003077707.1 254792870 8216366 1807255..1808424 1 NC_013008.1 hypothetical protein 1808424 yciM 8216366 yciM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077707.1 1807255 D 544404 CDS YP_003077708.1 254792871 8216367 1808617..1809354 1 NC_013008.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1809354 pyrF 8216367 pyrF Escherichia coli O157:H7 str. TW14359 orotidine 5'-phosphate decarboxylase YP_003077708.1 1808617 D 544404 CDS YP_003077709.1 254792872 8216368 1809354..1809680 1 NC_013008.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1809680 yciH 8216368 yciH Escherichia coli O157:H7 str. TW14359 translation initiation factor Sui1 YP_003077709.1 1809354 D 544404 CDS YP_003077710.1 254792873 8216369 complement(1809806..1810024) 1 NC_013008.1 lipoprotein 1810024 osmB 8216369 osmB Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003077710.1 1809806 R 544404 CDS YP_003077711.1 254792874 8216370 complement(1810293..1811042) 1 NC_013008.1 DNA-binding transcriptional regulator 1811042 yciT 8216370 yciT Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077711.1 1810293 R 544404 CDS YP_003077712.1 254792875 8216371 complement(1811132..1811314) 1 NC_013008.1 hypothetical protein 1811314 8216371 ECSP_1805 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077712.1 1811132 R 544404 CDS YP_003077713.1 254792876 8216372 complement(1811856..1813433) 1 NC_013008.1 modulator of Rnase II stability 1813433 gmr 8216372 gmr Escherichia coli O157:H7 str. TW14359 modulator of Rnase II stability YP_003077713.1 1811856 R 544404 CDS YP_003077714.1 254792877 8216373 complement(1813668..1815602) 1 NC_013008.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1815602 rnb 8216373 rnb Escherichia coli O157:H7 str. TW14359 exoribonuclease II YP_003077714.1 1813668 R 544404 CDS YP_003077715.1 254792878 8216374 complement(1815670..1816797) 1 NC_013008.1 oxidoreductase 1816797 yciW 8216374 yciW Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077715.1 1815670 R 544404 CDS YP_003077716.1 254792879 8216375 complement(1816941..1817729) 1 NC_013008.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 1817729 fabI 8216375 fabI Escherichia coli O157:H7 str. TW14359 enoyl-(acyl carrier protein) reductase YP_003077716.1 1816941 R 544404 CDS YP_003077717.1 254792880 8216376 1818207..1818773 1 NC_013008.1 transcriptional repressor 1818773 8216376 ECSP_1810 Escherichia coli O157:H7 str. TW14359 transcriptional repressor YP_003077717.1 1818207 D 544404 CDS YP_003077718.1 254792881 8216377 1818922..1820043 1 NC_013008.1 efflux pump 1820043 8216377 ECSP_1811 Escherichia coli O157:H7 str. TW14359 efflux pump YP_003077718.1 1818922 D 544404 CDS YP_003077719.1 254792882 8216378 1820043..1823132 1 NC_013008.1 efflux pump 1823132 8216378 ECSP_1812 Escherichia coli O157:H7 str. TW14359 efflux pump YP_003077719.1 1820043 D 544404 CDS YP_003077720.1 254792883 8216379 1823155..1824528 1 NC_013008.1 outer membrane channel protein 1824528 8216379 ECSP_1813 Escherichia coli O157:H7 str. TW14359 outer membrane channel protein YP_003077720.1 1823155 D 544404 CDS YP_003077721.1 254792884 8216380 1824537..1825700 1 NC_013008.1 membrane transport protein 1825700 8216380 ECSP_1814 Escherichia coli O157:H7 str. TW14359 membrane transport protein YP_003077721.1 1824537 D 544404 CDS YP_003077722.1 254792885 8216381 complement(1825752..1826558) 1 NC_013008.1 peptide transport system ATP-binding protein 1826558 sapF 8216381 sapF Escherichia coli O157:H7 str. TW14359 peptide transport system ATP-binding protein YP_003077722.1 1825752 R 544404 CDS YP_003077723.1 254792886 8216382 complement(1826560..1827552) 1 NC_013008.1 peptide transport system ATP-binding protein 1827552 sapD 8216382 sapD Escherichia coli O157:H7 str. TW14359 peptide transport system ATP-binding protein YP_003077723.1 1826560 R 544404 CDS YP_003077724.1 254792887 8216383 complement(1827552..1828442) 1 NC_013008.1 antimicrobial peptide ABC transporter membrane protein 1828442 sapC 8216383 sapC Escherichia coli O157:H7 str. TW14359 antimicrobial peptide ABC transporter membrane protein YP_003077724.1 1827552 R 544404 CDS YP_003077725.1 254792888 8216384 complement(1828429..1829394) 1 NC_013008.1 antimicrobial peptide ABC transporter membrane protein 1829394 sapB 8216384 sapB Escherichia coli O157:H7 str. TW14359 antimicrobial peptide ABC transporter membrane protein YP_003077725.1 1828429 R 544404 CDS YP_003077726.1 254792889 8216385 complement(1829391..1831034) 1 NC_013008.1 antimicrobial peptide transporter subunit 1831034 sapA 8216385 sapA Escherichia coli O157:H7 str. TW14359 antimicrobial peptide transporter subunit YP_003077726.1 1829391 R 544404 CDS YP_003077727.1 254792890 8216386 complement(1831347..1831592) 1 NC_013008.1 hypothetical protein 1831592 ymjA 8216386 ymjA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077727.1 1831347 R 544404 CDS YP_003077728.1 254792891 8216387 complement(1831726..1833111) 1 NC_013008.1 putrescine importer 1833111 puuP 8216387 puuP Escherichia coli O157:H7 str. TW14359 putrescine importer YP_003077728.1 1831726 R 544404 CDS YP_003077729.1 254792892 8216388 complement(1833414..1834832) 1 NC_013008.1 gamma-Glu-putrescine synthase 1834832 puuA 8216388 puuA Escherichia coli O157:H7 str. TW14359 gamma-Glu-putrescine synthase YP_003077729.1 1833414 R 544404 CDS YP_003077730.1 254792893 8216389 1835044..1835808 1 NC_013008.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1835808 puuD 8216389 puuD Escherichia coli O157:H7 str. TW14359 gamma-glutamyl-gamma-aminobutyrate hydrolase YP_003077730.1 1835044 D 544404 CDS YP_003077731.1 254792894 8216390 1835835..1836392 1 NC_013008.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1836392 puuR 8216390 puuR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor PuuR YP_003077731.1 1835835 D 544404 CDS YP_003077732.1 254792895 8216391 1836542..1838029 1 NC_013008.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1838029 puuC 8216391 puuC Escherichia coli O157:H7 str. TW14359 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_003077732.1 1836542 D 544404 CDS YP_003077733.1 254792896 8216392 1838031..1839311 1 NC_013008.1 gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding 1839311 puuB 8216392 puuB Escherichia coli O157:H7 str. TW14359 gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding YP_003077733.1 1838031 D 544404 CDS YP_003077734.1 254792897 8216393 1839349..1840614 1 NC_013008.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 1840614 puuE 8216393 puuE Escherichia coli O157:H7 str. TW14359 4-aminobutyrate aminotransferase YP_003077734.1 1839349 D 544404 CDS YP_003077735.1 254792898 8216394 complement(1840745..1841722) 1 NC_013008.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1841722 pspF 8216394 pspF Escherichia coli O157:H7 str. TW14359 phage shock protein operon transcriptional activator YP_003077735.1 1840745 R 544404 CDS YP_003077736.1 254792899 8216395 1841889..1842557 1 NC_013008.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1842557 pspA 8216395 pspA Escherichia coli O157:H7 str. TW14359 phage shock protein PspA YP_003077736.1 1841889 D 544404 CDS YP_003077737.1 254792900 8216396 1842611..1842835 1 NC_013008.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1842835 pspB 8216396 pspB Escherichia coli O157:H7 str. TW14359 phage shock protein B YP_003077737.1 1842611 D 544404 CDS YP_003077738.1 254792901 8216397 1842835..1843194 1 NC_013008.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1843194 pspC 8216397 pspC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator PspC YP_003077738.1 1842835 D 544404 CDS YP_003077739.1 254792902 8216398 1843203..1843424 1 NC_013008.1 peripheral inner membrane phage-shock protein 1843424 pspD 8216398 pspD Escherichia coli O157:H7 str. TW14359 peripheral inner membrane phage-shock protein YP_003077739.1 1843203 D 544404 CDS YP_003077740.1 254792903 8216399 1843499..1843813 1 NC_013008.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1843813 pspE 8216399 pspE Escherichia coli O157:H7 str. TW14359 thiosulfate:cyanide sulfurtransferase YP_003077740.1 1843499 D 544404 CDS YP_003077741.1 254792904 8216402 1847028..1847909 1 NC_013008.1 sugar ABC transporter membrane protein 1847909 ycjO 8216402 ycjO Escherichia coli O157:H7 str. TW14359 sugar ABC transporter membrane protein YP_003077741.1 1847028 D 544404 CDS YP_003077742.1 254792905 8216403 1847896..1848738 1 NC_013008.1 sugar ABC transporter membrane protein 1848738 ycjP 8216403 ycjP Escherichia coli O157:H7 str. TW14359 sugar ABC transporter membrane protein YP_003077742.1 1847896 D 544404 CDS YP_003077743.1 254792906 8216404 1848769..1849821 1 NC_013008.1 oxidoreductase 1849821 ycjQ 8216404 ycjQ Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077743.1 1848769 D 544404 CDS YP_003077744.1 254792907 8216405 1849839..1850627 1 NC_013008.1 hypothetical protein 1850627 ycjR 8216405 ycjR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077744.1 1849839 D 544404 CDS YP_003077745.1 254792908 8216406 1850637..1851692 1 NC_013008.1 oxidoreductase 1851692 ycjS 8216406 ycjS Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077745.1 1850637 D 544404 CDS YP_003077746.1 254792909 8216407 1851689..1853956 1 NC_013008.1 hydrolase 1853956 ycjT 8216407 ycjT Escherichia coli O157:H7 str. TW14359 hydrolase YP_003077746.1 1851689 D 544404 CDS YP_003077747.1 254792910 8216408 1853953..1854612 1 NC_013008.1 beta-phosphoglucomutase 1854612 ycjU 8216408 ycjU Escherichia coli O157:H7 str. TW14359 beta-phosphoglucomutase YP_003077747.1 1853953 D 544404 CDS YP_003077748.1 254792911 8216409 1854626..1855708 1 NC_013008.1 ATP-binding protein of a transport system 1855708 ycjV 8216409 ycjV Escherichia coli O157:H7 str. TW14359 ATP-binding protein of a transport system YP_003077748.1 1854626 D 544404 CDS YP_003077749.1 254792912 8216410 1855753..1856658 1 NC_013008.1 outer membrane porin 1856658 ompG 8216410 ompG Escherichia coli O157:H7 str. TW14359 outer membrane porin YP_003077749.1 1855753 D 544404 CDS YP_003077750.1 254792913 8216411 complement(1856769..1857767) 1 NC_013008.1 DNA-binding transcriptional regulator 1857767 ycjW 8216411 ycjW Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077750.1 1856769 R 544404 CDS YP_003077751.1 254792914 8216412 1857922..1859319 1 NC_013008.1 hypothetical protein 1859319 ycjX 8216412 ycjX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077751.1 1857922 D 544404 CDS YP_003077752.1 254792915 8216413 1859316..1860377 1 NC_013008.1 hypothetical protein 1860377 ycjF 8216413 ycjF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077752.1 1859316 D 544404 CDS YP_003077753.1 254792916 8216414 1860525..1862066 1 NC_013008.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1862066 tyrR 8216414 tyrR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator TyrR YP_003077753.1 1860525 D 544404 CDS YP_003077754.1 254792917 8216415 complement(1862110..1862616) 1 NC_013008.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1862616 tpx 8216415 tpx Escherichia coli O157:H7 str. TW14359 thiol peroxidase YP_003077754.1 1862110 R 544404 CDS YP_003077755.1 254792918 8216416 1862735..1863700 1 NC_013008.1 L-Ala-D/L-Glu epimerase 1863700 ycjG 8216416 ycjG Escherichia coli O157:H7 str. TW14359 L-Ala-D/L-Glu epimerase YP_003077755.1 1862735 D 544404 CDS YP_003077756.1 254792919 8216417 complement(1863675..1864403) 1 NC_013008.1 murein peptide amidase A 1864403 mpaA 8216417 mpaA Escherichia coli O157:H7 str. TW14359 murein peptide amidase A YP_003077756.1 1863675 R 544404 CDS YP_003077757.1 254792920 8216418 complement(1864694..1865332) 1 NC_013008.1 hypothetical protein 1865332 8216418 ECSP_1852 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077757.1 1864694 R 544404 CDS YP_003077758.1 254792921 8216420 complement(1866283..1867203) 1 NC_013008.1 hydrolase 1867203 ycjY 8216420 ycjY Escherichia coli O157:H7 str. TW14359 hydrolase YP_003077758.1 1866283 R 544404 CDS YP_003077759.1 254792922 8216421 1867341..1868240 1 NC_013008.1 DNA-binding transcriptional regulator 1868240 ycjZ 8216421 ycjZ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077759.1 1867341 D 544404 CDS YP_003077760.1 254792923 8216422 1868576..1870189 1 NC_013008.1 murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) ABC transporter periplasmic-binding protein 1870189 mppA 8216422 mppA Escherichia coli O157:H7 str. TW14359 murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) ABC transporter periplasmic-binding protein YP_003077760.1 1868576 D 544404 CDS YP_003077761.1 254792924 8216423 complement(1870240..1871271) 1 NC_013008.1 hypothetical protein 1871271 ynaI 8216423 ynaI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077761.1 1870240 R 544404 CDS YP_003077762.1 254792925 8216424 1871515..1871772 1 NC_013008.1 inner membrane protein 1871772 ynaJ 8216424 ynaJ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077762.1 1871515 D 544404 CDS YP_003077763.1 254792926 8216425 complement(1871822..1872772) 1 NC_013008.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1872772 8216425 ECSP_1859 Escherichia coli O157:H7 str. TW14359 universal stress protein UspE YP_003077763.1 1871822 R 544404 CDS YP_003077764.1 254792927 8216426 complement(1872924..1873676) 1 NC_013008.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1873676 fnr 8216426 fnr Escherichia coli O157:H7 str. TW14359 fumarate/nitrate reduction transcriptional regulator YP_003077764.1 1872924 R 544404 CDS YP_003077765.1 254792928 8216427 complement(1873871..1874386) 1 NC_013008.1 O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1874386 ogt 8216427 ogt Escherichia coli O157:H7 str. TW14359 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_003077765.1 1873871 R 544404 CDS YP_003077766.1 254792929 8216428 complement(1874397..1875923) 1 NC_013008.1 aminobenzoyl-glutamate transporter 1875923 abgT 8216428 abgT Escherichia coli O157:H7 str. TW14359 aminobenzoyl-glutamate transporter YP_003077766.1 1874397 R 544404 CDS YP_003077767.1 254792930 8216429 complement(1875960..1877405) 1 NC_013008.1 peptidase 1877405 abgB 8216429 abgB Escherichia coli O157:H7 str. TW14359 peptidase YP_003077767.1 1875960 R 544404 CDS YP_003077768.1 254792931 8216430 complement(1877405..1878715) 1 NC_013008.1 peptidase 1878715 abgA 8216430 abgA Escherichia coli O157:H7 str. TW14359 peptidase YP_003077768.1 1877405 R 544404 CDS YP_003077769.1 254792932 8216431 1878891..1879799 1 NC_013008.1 DNA-binding transcriptional regulator 1879799 abgR 8216431 abgR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077769.1 1878891 D 544404 CDS YP_003077770.1 254792933 8216432 1880129..1880692 1 NC_013008.1 hypothetical protein 1880692 ydaL 8216432 ydaL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077770.1 1880129 D 544404 CDS YP_003077771.1 254792934 8216433 complement(1880713..1881945) 1 NC_013008.1 diguanylate cyclase, GGDEF domain signalling protein 1881945 ydaM 8216433 ydaM Escherichia coli O157:H7 str. TW14359 diguanylate cyclase, GGDEF domain signalling protein YP_003077771.1 1880713 R 544404 CDS YP_003077772.1 254792935 8216434 1882200..1883183 1 NC_013008.1 zinc transporter 1883183 zntB 8216434 zntB Escherichia coli O157:H7 str. TW14359 zinc transporter YP_003077772.1 1882200 D 544404 CDS YP_003077773.1 254792936 8216435 complement(1883252..1883356) 1 NC_013008.1 hypothetical protein 1883356 8216435 ECSP_1869 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077773.1 1883252 R 544404 CDS YP_003077774.1 254792937 8216436 complement(1883413..1883649) 1 NC_013008.1 hypothetical protein 1883649 8216436 ECSP_1870 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077774.1 1883413 R 544404 CDS YP_003077775.1 254792938 8216437 1883661..1885034 1 NC_013008.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1885034 dbpA 8216437 dbpA Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase DbpA YP_003077775.1 1883661 D 544404 CDS YP_003077776.1 254792939 8216438 complement(1885163..1886098) 1 NC_013008.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1886098 ttcA 8216438 ttcA Escherichia coli O157:H7 str. TW14359 C32 tRNA thiolase YP_003077776.1 1885163 R 544404 CDS YP_003077777.1 254792940 8216439 complement(1886274..1886708) 1 NC_013008.1 stress-induced protein, ATP-binding protein 1886708 uspF 8216439 uspF Escherichia coli O157:H7 str. TW14359 stress-induced protein, ATP-binding protein YP_003077777.1 1886274 R 544404 CDS YP_003077778.1 254792941 8216441 complement(1888328..1891852) 1 NC_013008.1 fused pyruvate-flavodoxin oxidoreductase: conserved protein, conserved protein, FeS binding protein 1891852 ydbK 8216441 ydbK Escherichia coli O157:H7 str. TW14359 fused pyruvate-flavodoxin oxidoreductase: conserved protein, conserved protein, FeS binding protein YP_003077778.1 1888328 R 544404 CDS YP_003077779.1 254792942 8216442 1892126..1892392 1 NC_013008.1 hypothetical protein 1892392 ydbJ 8216442 ydbJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077779.1 1892126 D 544404 CDS YP_003077780.1 254792943 8216443 complement(1892389..1892811) 1 NC_013008.1 heat-inducible protein 1892811 hslJ 8216443 hslJ Escherichia coli O157:H7 str. TW14359 heat-inducible protein YP_003077780.1 1892389 R 544404 CDS YP_003077781.1 254792944 8216444 complement(1892922..1893911) 1 NC_013008.1 fermentative D-lactate dehydrogenase, NAD-dependent 1893911 ldhA 8216444 ldhA Escherichia coli O157:H7 str. TW14359 fermentative D-lactate dehydrogenase, NAD-dependent YP_003077781.1 1892922 R 544404 CDS YP_003077782.1 254792945 8216445 1894119..1896758 1 NC_013008.1 hypothetical protein 1896758 ydbH 8216445 ydbH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077782.1 1894119 D 544404 CDS YP_003077783.1 254792946 8216446 1896755..1896940 1 NC_013008.1 lipoprotein 1896940 ynbE 8216446 ynbE Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003077783.1 1896755 D 544404 CDS YP_003077784.1 254792947 8216447 1896948..1897271 1 NC_013008.1 hypothetical protein 1897271 ydbL 8216447 ydbL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077784.1 1896948 D 544404 CDS YP_003077785.1 254792948 8216448 1897685..1900720 1 NC_013008.1 hypothetical protein 1900720 8216448 ECSP_1882 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077785.1 1897685 D 544404 CDS YP_003077786.1 254792949 8216449 1900940..1903399 1 NC_013008.1 autotransporter-1 (AT-1) family protein 1903399 8216449 ECSP_1883 Escherichia coli O157:H7 str. TW14359 autotransporter-1 (AT-1) family protein YP_003077786.1 1900940 D 544404 CDS YP_003077787.1 254792950 8216450 1903619..1904479 1 NC_013008.1 oxidoreductase 1904479 ydbC 8216450 ydbC Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077787.1 1903619 D 544404 CDS YP_003077788.1 254792951 8216451 1904543..1906849 1 NC_013008.1 hypothetical protein 1906849 ydbD 8216451 ydbD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077788.1 1904543 D 544404 CDS YP_003077789.1 254792952 8216452 1907020..1907625 1 NC_013008.1 inner membrane protein 1907625 ynbA 8216452 ynbA Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077789.1 1907020 D 544404 CDS YP_003077790.1 254792953 8216453 1907625..1908521 1 NC_013008.1 CDP-diglyceride synthase 1908521 ynbB 8216453 ynbB Escherichia coli O157:H7 str. TW14359 CDP-diglyceride synthase YP_003077790.1 1907625 D 544404 CDS YP_003077791.1 254792954 8216454 1908537..1910294 1 NC_013008.1 hydrolase 1910294 ynbC 8216454 ynbC Escherichia coli O157:H7 str. TW14359 hydrolase YP_003077791.1 1908537 D 544404 CDS YP_003077792.1 254792955 8216455 1910308..1911600 1 NC_013008.1 phosphatase, inner membrane protein 1911600 ynbD 8216455 ynbD Escherichia coli O157:H7 str. TW14359 phosphatase, inner membrane protein YP_003077792.1 1910308 D 544404 CDS YP_003077793.1 254792956 8216456 complement(1911651..1912256) 1 NC_013008.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1912256 azoR 8216456 azoR Escherichia coli O157:H7 str. TW14359 azoreductase YP_003077793.1 1911651 R 544404 CDS YP_003077794.1 254792957 8216457 1912457..1916359 1 NC_013008.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1916359 hrpA 8216457 hrpA Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase HrpA YP_003077794.1 1912457 D 544404 CDS YP_003077795.1 254792958 8216458 1916505..1916930 1 NC_013008.1 hypothetical protein 1916930 8216458 ECSP_1892 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077795.1 1916505 D 544404 CDS YP_003077796.1 254792959 8216459 1916935..1917273 1 NC_013008.1 hypothetical protein 1917273 8216459 ECSP_1893 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077796.1 1916935 D 544404 CDS YP_003077797.1 254792960 8216460 1917260..1917691 1 NC_013008.1 hypothetical protein 1917691 8216460 ECSP_1894 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077797.1 1917260 D 544404 CDS YP_003077798.1 254792961 8216461 1917816..1918193 1 NC_013008.1 hypothetical protein 1918193 8216461 ECSP_1895 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077798.1 1917816 D 544404 CDS YP_003077799.1 254792962 8216462 1918309..1919109 1 NC_013008.1 hypothetical protein 1919109 ydcF 8216462 ydcF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077799.1 1918309 D 544404 CDS YP_003077800.1 254792963 8216463 1919306..1920745 1 NC_013008.1 NAD-linked; aldehyde dehydrogenase 1920745 aldA 8216463 aldA Escherichia coli O157:H7 str. TW14359 aldehyde dehydrogenase YP_003077800.1 1919306 D 544404 CDS YP_003077801.1 254792964 8216464 complement(1920787..1921788) 1 NC_013008.1 glyceraldehyde-3-phosphate dehydrogenase 1921788 gapC 8216464 gapC Escherichia coli O157:H7 str. TW14359 glyceraldehyde-3-phosphate dehydrogenase YP_003077801.1 1920787 R 544404 CDS YP_003077802.1 254792965 8216465 1921977..1922507 1 NC_013008.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1922507 cybB 8216465 cybB Escherichia coli O157:H7 str. TW14359 cytochrome b561 YP_003077802.1 1921977 D 544404 CDS YP_003077803.1 254792966 8216466 1922752..1922925 1 NC_013008.1 hypothetical protein 1922925 ydcA 8216466 ydcA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077803.1 1922752 D 544404 CDS YP_003077804.1 254792967 8216467 complement(1923037..1923204) 1 NC_013008.1 regulatory peptide 1923204 mokB 8216467 mokB Escherichia coli O157:H7 str. TW14359 regulatory peptide YP_003077804.1 1923037 R 544404 CDS YP_003077805.1 254792968 8216468 1923545..1925185 1 NC_013008.1 methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1925185 trg 8216468 trg Escherichia coli O157:H7 str. TW14359 methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor YP_003077805.1 1923545 D 544404 CDS YP_003077806.1 254792969 8216469 complement(1925223..1926146) 1 NC_013008.1 DNA-binding transcriptional regulator 1926146 ydcI 8216469 ydcI Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077806.1 1925223 R 544404 CDS YP_003077807.1 254792970 8216470 1927182..1927706 1 NC_013008.1 hypothetical protein 1927706 ydcJ 8216470 ydcJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077807.1 1927182 D 544404 CDS YP_003077808.1 254792971 8216471 1927931..1929586 1 NC_013008.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1929586 mdoD 8216471 mdoD Escherichia coli O157:H7 str. TW14359 glucan biosynthesis protein D YP_003077808.1 1927931 D 544404 CDS YP_003077809.1 254792972 8216472 1929726..1929950 1 NC_013008.1 hypothetical protein 1929950 ydcH 8216472 ydcH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077809.1 1929726 D 544404 CDS YP_003077810.1 254792973 8216474 complement(1930544..1931524) 1 NC_013008.1 hypothetical protein 1931524 ydcK 8216474 ydcK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077810.1 1930544 R 544404 CDS YP_003077811.1 254792974 8216475 1931648..1932640 1 NC_013008.1 potassium-tellurite ethidium and proflavin transporter 1932640 tehA 8216475 tehA Escherichia coli O157:H7 str. TW14359 potassium-tellurite ethidium and proflavin transporter YP_003077811.1 1931648 D 544404 CDS YP_003077812.1 254792975 8216476 1932637..1933230 1 NC_013008.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1933230 tehB 8216476 tehB Escherichia coli O157:H7 str. TW14359 tellurite resistance protein TehB YP_003077812.1 1932637 D 544404 CDS YP_003077813.1 254792976 8216477 1933534..1934202 1 NC_013008.1 lipoprotein 1934202 ydcL 8216477 ydcL Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003077813.1 1933534 D 544404 CDS YP_003077814.1 254792977 8216479 1935502..1936038 1 NC_013008.1 DNA-binding transcriptional regulator 1936038 ydcN 8216479 ydcN Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077814.1 1935502 D 544404 CDS YP_003077815.1 254792978 8216480 1936111..1938072 1 NC_013008.1 peptidase 1938072 ydcP 8216480 ydcP Escherichia coli O157:H7 str. TW14359 peptidase YP_003077815.1 1936111 D 544404 CDS YP_003077816.1 254792979 8216481 complement(1938164..1938394) 1 NC_013008.1 hypothetical protein 1938394 yncJ 8216481 yncJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077816.1 1938164 R 544404 CDS YP_003077817.1 254792980 8216482 complement(1938451..1938573) 1 NC_013008.1 hypothetical protein 1938573 8216482 ECSP_1916 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077817.1 1938451 R 544404 CDS YP_003077818.1 254792981 8216483 1938616..1938792 1 NC_013008.1 hypothetical protein 1938792 yncN 8216483 yncN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077818.1 1938616 D 544404 CDS YP_003077819.1 254792982 8216484 1938817..1939254 1 NC_013008.1 DNA-binding transcriptional regulator 1939254 ydcQ 8216484 ydcQ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077819.1 1938817 D 544404 CDS YP_003077820.1 254792983 8216485 1939333..1940739 1 NC_013008.1 DNA-binding transcriptional regulator with an aminotransferase domain 1940739 ydcR 8216485 ydcR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator with an aminotransferase domain YP_003077820.1 1939333 D 544404 CDS YP_003077821.1 254792984 8216486 1940984..1942129 1 NC_013008.1 spermidine/putrescine ABC transporter periplasmic-binding protein 1942129 ydcS 8216486 ydcS Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter periplasmic-binding protein YP_003077821.1 1940984 D 544404 CDS YP_003077822.1 254792985 8216487 1942147..1943160 1 NC_013008.1 spermidine/putrescine ABC transporter ATP-binding protein 1943160 ydcT 8216487 ydcT Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter ATP-binding protein YP_003077822.1 1942147 D 544404 CDS YP_003077823.1 254792986 8216488 1943161..1944102 1 NC_013008.1 spermidine/putrescine ABC transporter membrane protein 1944102 ydcU 8216488 ydcU Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter membrane protein YP_003077823.1 1943161 D 544404 CDS YP_003077824.1 254792987 8216489 1944092..1944886 1 NC_013008.1 spermidine/putrescine ABC transporter membrane protein 1944886 ydcV 8216489 ydcV Escherichia coli O157:H7 str. TW14359 spermidine/putrescine ABC transporter membrane protein YP_003077824.1 1944092 D 544404 CDS YP_003077825.1 254792988 8216490 1944908..1946332 1 NC_013008.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1946332 ydcW 8216490 ydcW Escherichia coli O157:H7 str. TW14359 gamma-aminobutyraldehyde dehydrogenase YP_003077825.1 1944908 D 544404 CDS YP_003077826.1 254792989 8216491 complement(1946329..1946445) 1 NC_013008.1 hypothetical protein 1946445 8216491 ECSP_1925 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077826.1 1946329 R 544404 CDS YP_003077827.1 254792990 8216492 1946719..1946892 1 NC_013008.1 inner membrane protein 1946892 ydcX 8216492 ydcX Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077827.1 1946719 D 544404 CDS YP_003077828.1 254792991 8216493 1946978..1947211 1 NC_013008.1 hypothetical protein 1947211 ydcY 8216493 ydcY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077828.1 1946978 D 544404 CDS YP_003077829.1 254792992 8216494 complement(1947212..1947661) 1 NC_013008.1 inner membrane protein 1947661 ydcZ 8216494 ydcZ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003077829.1 1947212 R 544404 CDS YP_003077830.1 254792993 8216495 complement(1947658..1948176) 1 NC_013008.1 acyl-CoA N-acyltransferase domain-containing acyltransferase 1948176 yncA 8216495 yncA Escherichia coli O157:H7 str. TW14359 acyl-CoA N-acyltransferase domain-containing acyltransferase YP_003077830.1 1947658 R 544404 CDS YP_003077831.1 254792994 8216496 1948357..1949394 1 NC_013008.1 oxidoreductase 1949394 yncB 8216496 yncB Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077831.1 1948357 D 544404 CDS YP_003077832.1 254792995 8216497 1949592..1950257 1 NC_013008.1 DNA-binding transcriptional regulator 1950257 yncC 8216497 yncC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077832.1 1949592 D 544404 CDS YP_003077833.1 254792996 8216498 complement(1950293..1952395) 1 NC_013008.1 iron outer membrane transporter 1952395 yncD 8216498 yncD Escherichia coli O157:H7 str. TW14359 iron outer membrane transporter YP_003077833.1 1950293 R 544404 CDS YP_003077834.1 254792997 8216499 1952637..1953698 1 NC_013008.1 hypothetical protein 1953698 yncE 8216499 yncE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077834.1 1952637 D 544404 CDS YP_003077835.1 254792998 8216500 complement(1953813..1955312) 1 NC_013008.1 L-asparagine transporter 1955312 ansP 8216500 ansP Escherichia coli O157:H7 str. TW14359 L-asparagine transporter YP_003077835.1 1953813 R 544404 CDS YP_003077836.1 254792999 8216501 1955579..1956196 1 NC_013008.1 hypothetical protein 1956196 yncG 8216501 yncG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077836.1 1955579 D 544404 CDS YP_003077837.1 254793000 8216502 1956272..1956484 1 NC_013008.1 hypothetical protein 1956484 yncH 8216502 yncH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077837.1 1956272 D 544404 CDS YP_003077838.1 254793001 8216503 complement(1956897..1957043) 1 NC_013008.1 hypothetical protein 1957043 8216503 ECSP_1937 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077838.1 1956897 R 544404 CDS YP_003077839.1 254793002 8216504 1957269..1959413 1 NC_013008.1 hypothetical protein 1959413 vgrE 8216504 vgrE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077839.1 1957269 D 544404 CDS YP_003077840.1 254793003 8216505 1961712..1963682 1 NC_013008.1 hypothetical protein 1963682 8216505 ECSP_1939 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077840.1 1961712 D 544404 CDS YP_003077841.1 254793004 8216506 1963879..1964088 1 NC_013008.1 hypothetical protein 1964088 8216506 ECSP_1940 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077841.1 1963879 D 544404 CDS YP_003077842.1 254793005 8216507 1964155..1964304 1 NC_013008.1 hypothetical protein 1964304 8216507 ECSP_1941 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077842.1 1964155 D 544404 CDS YP_003077843.1 254793006 8216508 1964596..1964775 1 NC_013008.1 partial H repeat-associated protein of Rhs element 1964775 8216508 ECSP_1942 Escherichia coli O157:H7 str. TW14359 partial H repeat-associated protein of Rhs element YP_003077843.1 1964596 D 544404 CDS YP_003077844.1 254793007 8216509 1964875..1965765 1 NC_013008.1 transposase 1965765 8216509 ECSP_1943 Escherichia coli O157:H7 str. TW14359 transposase YP_003077844.1 1964875 D 544404 CDS YP_003077845.1 254793008 8216510 1965864..1966091 1 NC_013008.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1966091 ydcE 8216510 ydcE Escherichia coli O157:H7 str. TW14359 4-oxalocrotonate tautomerase YP_003077845.1 1965864 D 544404 CDS YP_003077846.1 254793009 8216511 complement(1966095..1966538) 1 NC_013008.1 hypothetical protein 1966538 yddH 8216511 yddH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077846.1 1966095 R 544404 CDS YP_003077847.1 254793010 8216512 complement(1966542..1966712) 1 NC_013008.1 hypothetical protein 1966712 8216512 ECSP_1946 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077847.1 1966542 R 544404 CDS YP_003077848.1 254793011 8216514 complement(1967777..1968670) 1 NC_013008.1 hypothetical protein 1968670 yddE 8216514 yddE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077848.1 1967777 R 544404 CDS YP_003077849.1 254793012 8216515 complement(1968749..1969429) 1 NC_013008.1 nitrate reductase 2 (NRZ) subunit gamma 1969429 narV 8216515 narV Escherichia coli O157:H7 str. TW14359 nitrate reductase 2 (NRZ) subunit gamma YP_003077849.1 1968749 R 544404 CDS YP_003077850.1 254793013 8216516 complement(1969426..1970121) 1 NC_013008.1 nitrate reductase 2 (NRZ) subunit delta 1970121 narW 8216516 narW Escherichia coli O157:H7 str. TW14359 nitrate reductase 2 (NRZ) subunit delta YP_003077850.1 1969426 R 544404 CDS YP_003077851.1 254793014 8216517 complement(1970121..1971665) 1 NC_013008.1 nitrate reductase 2 (NRZ) subunit beta 1971665 narY 8216517 narY Escherichia coli O157:H7 str. TW14359 nitrate reductase 2 (NRZ) subunit beta YP_003077851.1 1970121 R 544404 CDS YP_003077852.1 254793015 8216518 complement(1971662..1975402) 1 NC_013008.1 nitrate reductase 2 (NRZ) subunit alpha 1975402 narZ 8216518 narZ Escherichia coli O157:H7 str. TW14359 nitrate reductase 2 (NRZ) subunit alpha YP_003077852.1 1971662 R 544404 CDS YP_003077853.1 254793016 8216519 complement(1975484..1976872) 1 NC_013008.1 nitrate/nitrite transporter 1976872 narU 8216519 narU Escherichia coli O157:H7 str. TW14359 nitrate/nitrite transporter YP_003077853.1 1975484 R 544404 CDS YP_003077854.1 254793017 8216520 complement(1977178..1978437) 1 NC_013008.1 non-LEE-encoded type III effector 1978437 espR1 8216520 espR1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077854.1 1977178 R 544404 CDS YP_003077855.1 254793018 8216521 complement(1978500..1979168) 1 NC_013008.1 hypothetical protein 1979168 8216521 ECSP_1955 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077855.1 1978500 R 544404 CDS YP_003077856.1 254793019 8216522 complement(1979927..1981027) 1 NC_013008.1 outer membrane porin protein 1981027 8216522 ECSP_1956 Escherichia coli O157:H7 str. TW14359 outer membrane porin protein YP_003077856.1 1979927 R 544404 CDS YP_003077857.1 254793020 8216523 complement(1981286..1982167) 1 NC_013008.1 hypothetical protein 1982167 yddG 8216523 yddG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077857.1 1981286 R 544404 CDS YP_003077858.1 254793021 8216525 1985459..1986343 1 NC_013008.1 formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible 1986343 fdnH 8216525 fdnH Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible YP_003077858.1 1985459 D 544404 CDS YP_003077859.1 254793022 8216526 1986336..1986989 1 NC_013008.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1986989 fdnI 8216526 fdnI Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-N subunit gamma YP_003077859.1 1986336 D 544404 CDS YP_003077860.1 254793023 8216527 complement(1987217..1987501) 1 NC_013008.1 DNA-binding transcriptional regulator 1987501 yddM 8216527 yddM Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077860.1 1987217 R 544404 CDS YP_003077861.1 254793024 8216528 complement(1987647..1988657) 1 NC_013008.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1988657 adhP 8216528 adhP Escherichia coli O157:H7 str. TW14359 alcohol dehydrogenase YP_003077861.1 1987647 R 544404 CDS YP_003077862.1 254793025 8216529 complement(1988791..1990488) 1 NC_013008.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1990488 sfcA 8216529 sfcA Escherichia coli O157:H7 str. TW14359 malate dehydrogenase YP_003077862.1 1988791 R 544404 CDS YP_003077863.1 254793026 8216530 complement(1990645..1990782) 1 NC_013008.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1990782 rpsV 8216530 rpsV Escherichia coli O157:H7 str. TW14359 30S ribosomal subunit S22 YP_003077863.1 1990645 R 544404 CDS YP_003077864.1 254793027 8216531 complement(1990884..1991099) 1 NC_013008.1 biofilm-dependent modulation protein 1991099 bdm 8216531 bdm Escherichia coli O157:H7 str. TW14359 biofilm-dependent modulation protein YP_003077864.1 1990884 R 544404 CDS YP_003077865.1 254793028 8216532 1991266..1991406 1 NC_013008.1 hypothetical protein 1991406 8216532 ECSP_1966 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077865.1 1991266 D 544404 CDS YP_003077866.1 254793029 8216533 1991444..1991875 1 NC_013008.1 osmotically inducible, stress-inducible membrane protein 1991875 osmC 8216533 osmC Escherichia coli O157:H7 str. TW14359 osmotically inducible, stress-inducible membrane protein YP_003077866.1 1991444 D 544404 CDS YP_003077867.1 254793030 8216534 complement(1991931..1992857) 1 NC_013008.1 D-ala-D-ala ABC transporter ATP-binding protein 1992857 ddpF 8216534 ddpF Escherichia coli O157:H7 str. TW14359 D-ala-D-ala ABC transporter ATP-binding protein YP_003077867.1 1991931 R 544404 CDS YP_003077868.1 254793031 8216535 complement(1992850..1993836) 1 NC_013008.1 D-ala-D-ala ABC transporter ATP-binding protein 1993836 ddpD 8216535 ddpD Escherichia coli O157:H7 str. TW14359 D-ala-D-ala ABC transporter ATP-binding protein YP_003077868.1 1992850 R 544404 CDS YP_003077869.1 254793032 8216536 complement(1993833..1994729) 1 NC_013008.1 ATP-dependent peptide transporter membrane subunit 1994729 ddpC 8216536 ddpC Escherichia coli O157:H7 str. TW14359 ATP-dependent peptide transporter membrane subunit YP_003077869.1 1993833 R 544404 CDS YP_003077870.1 254793033 8216537 complement(1994726..1995706) 1 NC_013008.1 D-ala-D-ala ABC transporter membrane protein 1995706 ddpB 8216537 ddpB Escherichia coli O157:H7 str. TW14359 D-ala-D-ala ABC transporter membrane protein YP_003077870.1 1994726 R 544404 CDS YP_003077871.1 254793034 8216538 complement(1995750..1997300) 1 NC_013008.1 D-ala-D-ala ABC transporter periplasmic-binding protein 1997300 ddpA 8216538 ddpA Escherichia coli O157:H7 str. TW14359 D-ala-D-ala ABC transporter periplasmic-binding protein YP_003077871.1 1995750 R 544404 CDS YP_003077872.1 254793035 8216539 complement(1997314..1997895) 1 NC_013008.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 1997895 ddpX 8216539 ddpX Escherichia coli O157:H7 str. TW14359 D-alanyl-D-alanine dipeptidase YP_003077872.1 1997314 R 544404 CDS YP_003077873.1 254793036 8216541 complement(2000567..2001949) 1 NC_013008.1 diguanylate cyclase 2001949 yddV 8216541 yddV Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003077873.1 2000567 R 544404 CDS YP_003077874.1 254793037 8216542 complement(2002326..2003645) 1 NC_013008.1 lipoprotein 2003645 yddW 8216542 yddW Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003077874.1 2002326 R 544404 CDS YP_003077875.1 254793038 8216543 complement(2003776..2005311) 1 NC_013008.1 glutamate:gamma-aminobutyric acid antiporter 2005311 gadC 8216543 gadC Escherichia coli O157:H7 str. TW14359 glutamate:gamma-aminobutyric acid antiporter YP_003077875.1 2003776 R 544404 CDS YP_003077876.1 254793039 8216544 complement(2005467..2006867) 1 NC_013008.1 glutamate decarboxylase B, PLP-dependent 2006867 gadB 8216544 gadB Escherichia coli O157:H7 str. TW14359 glutamate decarboxylase B, PLP-dependent YP_003077876.1 2005467 R 544404 CDS YP_003077877.1 254793040 8216545 complement(2007228..2010023) 1 NC_013008.1 peptidase 2010023 pqqL 8216545 pqqL Escherichia coli O157:H7 str. TW14359 peptidase YP_003077877.1 2007228 R 544404 CDS YP_003077878.1 254793041 8216546 complement(2010068..2012440) 1 NC_013008.1 porin protein 2012440 yddB 8216546 yddB Escherichia coli O157:H7 str. TW14359 porin protein YP_003077878.1 2010068 R 544404 CDS YP_003077879.1 254793042 8216547 complement(2012478..2014163) 1 NC_013008.1 fused multidrug transporter subunits of ABC superfamily: membrane component, ATP-binding protein 2014163 yddA 8216547 yddA Escherichia coli O157:H7 str. TW14359 fused multidrug transporter subunits of ABC superfamily: membrane component, ATP-binding protein YP_003077879.1 2012478 R 544404 CDS YP_003077880.1 254793043 8216548 complement(2014454..2015611) 1 NC_013008.1 hypothetical protein 2015611 ydeM 8216548 ydeM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077880.1 2014454 R 544404 CDS YP_003077881.1 254793044 8216549 complement(2015663..2015770) 1 NC_013008.1 hypothetical protein 2015770 8216549 ECSP_1983 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077881.1 2015663 R 544404 CDS YP_003077882.1 254793045 8216550 complement(2015873..2017345) 1 NC_013008.1 hypothetical protein 2017345 ydeN 8216550 ydeN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077882.1 2015873 R 544404 CDS YP_003077883.1 254793046 8216551 complement(2017749..2018510) 1 NC_013008.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 2018510 ydeO 8216551 ydeO Escherichia coli O157:H7 str. TW14359 transcriptional regulator YdeO YP_003077883.1 2017749 R 544404 CDS YP_003077884.1 254793047 8216552 complement(2019029..2021308) 1 NC_013008.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase 2021308 ydeP 8216552 ydeP Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003077884.1 2019029 R 544404 CDS YP_003077885.1 254793048 8216553 complement(2021642..2022556) 1 NC_013008.1 F9 fimbriae adhesin 2022556 fmlD 8216553 fmlD Escherichia coli O157:H7 str. TW14359 F9 fimbriae adhesin YP_003077885.1 2021642 R 544404 CDS YP_003077886.1 254793049 8216554 complement(2022616..2023119) 1 NC_013008.1 F9 fimbriae protein 2023119 ydeR 8216554 ydeR Escherichia coli O157:H7 str. TW14359 F9 fimbriae protein YP_003077886.1 2022616 R 544404 CDS YP_003077887.1 254793050 8216555 complement(2023132..2023662) 1 NC_013008.1 F9 fimbriae protein 2023662 ydeS 8216555 ydeS Escherichia coli O157:H7 str. TW14359 F9 fimbriae protein YP_003077887.1 2023132 R 544404 CDS YP_003077888.1 254793051 8216556 complement(2023676..2026327) 1 NC_013008.1 F9 fimbriae usher protein 2026327 fmlC 8216556 fmlC Escherichia coli O157:H7 str. TW14359 F9 fimbriae usher protein YP_003077888.1 2023676 R 544404 CDS YP_003077889.1 254793052 8216557 complement(2026369..2027079) 1 NC_013008.1 F9 fimbriae chaperone 2027079 fmlB 8216557 fmlB Escherichia coli O157:H7 str. TW14359 F9 fimbriae chaperone YP_003077889.1 2026369 R 544404 CDS YP_003077890.1 254793053 8216558 complement(2027440..2028003) 1 NC_013008.1 major subunit of F9 fimbriae 2028003 fmlA 8216558 fmlA Escherichia coli O157:H7 str. TW14359 major subunit of F9 fimbriae YP_003077890.1 2027440 R 544404 CDS YP_003077891.1 254793054 8216559 complement(2028437..2028640) 1 NC_013008.1 transcriptional regulator 2028640 yneL 8216559 yneL Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003077891.1 2028437 R 544404 CDS YP_003077892.1 254793055 8216560 complement(2028977..2029999) 1 NC_013008.1 regulator with hipB 2029999 hipA 8216560 hipA Escherichia coli O157:H7 str. TW14359 regulator with hipB YP_003077892.1 2028977 R 544404 CDS YP_003077893.1 254793056 8216561 complement(2031554..2035585) 1 NC_013008.1 lipoprotein 2035585 ydeK 8216561 ydeK Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003077893.1 2031554 R 544404 CDS YP_003077894.1 254793057 8216562 complement(2036116..2037708) 1 NC_013008.1 autoinducer-2 (AI-2) kinase 2037708 lsrK 8216562 lsrK Escherichia coli O157:H7 str. TW14359 autoinducer-2 (AI-2) kinase YP_003077894.1 2036116 R 544404 CDS YP_003077895.1 254793058 8216563 complement(2037787..2038740) 1 NC_013008.1 lsr operon transcriptional repressor 2038740 lsrR 8216563 lsrR Escherichia coli O157:H7 str. TW14359 lsr operon transcriptional repressor YP_003077895.1 2037787 R 544404 CDS YP_003077896.1 254793059 8216564 2038989..2040524 1 NC_013008.1 fused AI2 transporter subunits of ABC superfamily: ATP-binding proteins 2040524 lsrA 8216564 lsrA Escherichia coli O157:H7 str. TW14359 fused AI2 transporter subunits of ABC superfamily: ATP-binding proteins YP_003077896.1 2038989 D 544404 CDS YP_003077897.1 254793060 8216565 2040518..2041546 1 NC_013008.1 AI2 transporter, membrane component of ABC superfamily 2041546 lsrC 8216565 lsrC Escherichia coli O157:H7 str. TW14359 AI2 transporter, membrane component of ABC superfamily YP_003077897.1 2040518 D 544404 CDS YP_003077898.1 254793061 8216566 2041546..2042538 1 NC_013008.1 AI2 transporter, membrane component of ABC superfamily 2042538 lsrD 8216566 lsrD Escherichia coli O157:H7 str. TW14359 AI2 transporter, membrane component of ABC superfamily YP_003077898.1 2041546 D 544404 CDS YP_003077899.1 254793062 8216567 2042550..2043572 1 NC_013008.1 AI2 transporter, periplasmic-binding component of ABC superfamily 2043572 lsrB 8216567 lsrB Escherichia coli O157:H7 str. TW14359 AI2 transporter, periplasmic-binding component of ABC superfamily YP_003077899.1 2042550 D 544404 CDS YP_003077900.1 254793063 8216568 2043599..2044474 1 NC_013008.1 aldolase 2044474 lsrF 8216568 lsrF Escherichia coli O157:H7 str. TW14359 aldolase YP_003077900.1 2043599 D 544404 CDS YP_003077901.1 254793064 8216569 2044498..2044788 1 NC_013008.1 autoinducer-2 (AI-2) modifying protein LsrG 2044788 lsrG 8216569 lsrG Escherichia coli O157:H7 str. TW14359 autoinducer-2 (AI-2) modifying protein LsrG YP_003077901.1 2044498 D 544404 CDS YP_003077902.1 254793065 8216570 2044845..2045603 1 NC_013008.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 2045603 tam 8216570 tam Escherichia coli O157:H7 str. TW14359 trans-aconitate 2-methyltransferase YP_003077902.1 2044845 D 544404 CDS YP_003077903.1 254793066 8216571 complement(2045607..2046521) 1 NC_013008.1 hypothetical protein 2046521 yneE 8216571 yneE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077903.1 2045607 R 544404 CDS YP_003077904.1 254793067 8216572 complement(2046718..2048169) 1 NC_013008.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 2048169 uxaB 8216572 uxaB Escherichia coli O157:H7 str. TW14359 altronate oxidoreductase YP_003077904.1 2046718 R 544404 CDS YP_003077905.1 254793068 8216573 complement(2048396..2049343) 1 NC_013008.1 diguanylate cyclase 2049343 yneF 8216573 yneF Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003077905.1 2048396 R 544404 CDS YP_003077906.1 254793069 8216574 complement(2049953..2050312) 1 NC_013008.1 hypothetical protein 2050312 yneG 8216574 yneG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077906.1 2049953 R 544404 CDS YP_003077907.1 254793070 8216575 complement(2050312..2051238) 1 NC_013008.1 catalyzes the formation of glutamate from glutamine; glutaminase 2051238 yneH 8216575 yneH Escherichia coli O157:H7 str. TW14359 glutaminase YP_003077907.1 2050312 R 544404 CDS YP_003077908.1 254793071 8216576 complement(2051302..2052690) 1 NC_013008.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 2052690 yneI 8216576 yneI Escherichia coli O157:H7 str. TW14359 succinate semialdehyde dehydrogenase YP_003077908.1 2051302 R 544404 CDS YP_003077909.1 254793072 8216577 2052791..2053672 1 NC_013008.1 DNA-binding transcriptional regulator 2053672 yneJ 8216577 yneJ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077909.1 2052791 D 544404 CDS YP_003077910.1 254793073 8216579 2055016..2056206 1 NC_013008.1 sugar efflux transporter 2056206 ydeA 8216579 ydeA Escherichia coli O157:H7 str. TW14359 sugar efflux transporter YP_003077910.1 2055016 D 544404 CDS YP_003077911.1 254793074 8216580 complement(2056231..2056896) 1 NC_013008.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 2056896 marC 8216580 marC Escherichia coli O157:H7 str. TW14359 multiple drug resistance protein MarC YP_003077911.1 2056231 R 544404 CDS YP_003077912.1 254793075 8216581 2057108..2057542 1 NC_013008.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 2057542 marR 8216581 marR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor MarR YP_003077912.1 2057108 D 544404 CDS YP_003077913.1 254793076 8216582 2057562..2057945 1 NC_013008.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 2057945 marA 8216582 marA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator MarA YP_003077913.1 2057562 D 544404 CDS YP_003077914.1 254793077 8216583 2057977..2058195 1 NC_013008.1 hypothetical protein 2058195 marB 8216583 marB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077914.1 2057977 D 544404 CDS YP_003077915.1 254793078 8216584 complement(2058226..2059125) 1 NC_013008.1 O-acetylserine/cysteine export protein 2059125 ydeD 8216584 ydeD Escherichia coli O157:H7 str. TW14359 O-acetylserine/cysteine export protein YP_003077915.1 2058226 R 544404 CDS YP_003077916.1 254793079 8216585 2059320..2060507 1 NC_013008.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 2060507 ydeE 8216585 ydeE Escherichia coli O157:H7 str. TW14359 MFS-type transporter YdeE YP_003077916.1 2059320 D 544404 CDS YP_003077917.1 254793080 8216586 complement(2060548..2060943) 1 NC_013008.1 hypothetical protein 2060943 8216586 ECSP_2020 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077917.1 2060548 R 544404 CDS YP_003077918.1 254793081 8216587 2061026..2062009 1 NC_013008.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrA 2062009 ftrA 8216587 ftrA Escherichia coli O157:H7 str. TW14359 transcriptional activator FtrA YP_003077918.1 2061026 D 544404 CDS YP_003077919.1 254793082 8216588 complement(2062431..2063321) 1 NC_013008.1 hypothetical protein 2063321 ydeH 8216588 ydeH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077919.1 2062431 R 544404 CDS YP_003077920.1 254793083 8216589 complement(2063576..2063968) 1 NC_013008.1 hypothetical protein 2063968 ydeI 8216589 ydeI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077920.1 2063576 R 544404 CDS YP_003077921.1 254793084 8216590 2064244..2064762 1 NC_013008.1 competence damage-inducible protein A 2064762 ydeJ 8216590 ydeJ Escherichia coli O157:H7 str. TW14359 competence damage-inducible protein A YP_003077921.1 2064244 D 544404 CDS YP_003077922.1 254793085 8216591 complement(2064807..2066852) 1 NC_013008.1 dipeptidyl carboxypeptidase II 2066852 dcp 8216591 dcp Escherichia coli O157:H7 str. TW14359 dipeptidyl carboxypeptidase II YP_003077922.1 2064807 R 544404 CDS YP_003077923.1 254793086 8216592 2066989..2067735 1 NC_013008.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 2067735 ydfG 8216592 ydfG Escherichia coli O157:H7 str. TW14359 3-hydroxy acid dehydrogenase YP_003077923.1 2066989 D 544404 CDS YP_003077924.1 254793087 8216593 2067824..2068510 1 NC_013008.1 DNA-binding transcriptional regulator 2068510 ydfH 8216593 ydfH Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003077924.1 2067824 D 544404 CDS YP_003077925.1 254793088 8216594 2068687..2068890 1 NC_013008.1 hypothetical protein 2068890 ydfZ 8216594 ydfZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077925.1 2068687 D 544404 CDS YP_003077926.1 254793089 8216595 complement(2068926..2070386) 1 NC_013008.1 mannonate dehydrogenase 2070386 ydfI 8216595 ydfI Escherichia coli O157:H7 str. TW14359 mannonate dehydrogenase YP_003077926.1 2068926 R 544404 CDS YP_003077927.1 254793090 8216596 complement(2070475..2071758) 1 NC_013008.1 transporter 2071758 ydfJ 8216596 ydfJ Escherichia coli O157:H7 str. TW14359 transporter YP_003077927.1 2070475 R 544404 CDS YP_003077928.1 254793091 8216597 complement(2072294..2072935) 1 NC_013008.1 non-LEE-encoded type III effector 2072935 8216597 ECSP_2031 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077928.1 2072294 R 544404 CDS YP_003077929.1 254793092 8216598 complement(2073017..2073646) 1 NC_013008.1 non-LEE-encoded type III effector 2073646 8216598 ECSP_2032 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077929.1 2073017 R 544404 CDS YP_003077930.1 254793093 8216599 complement(2073719..2074294) 1 NC_013008.1 non-LEE-encoded type III effector 2074294 8216599 ECSP_2033 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077930.1 2073719 R 544404 CDS YP_003077931.1 254793094 8216600 complement(2074408..2074677) 1 NC_013008.1 hypothetical protein 2074677 8216600 ECSP_2034 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077931.1 2074408 R 544404 CDS YP_003077932.1 254793095 8216601 complement(2074679..2075992) 1 NC_013008.1 hypothetical protein 2075992 8216601 ECSP_2035 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077932.1 2074679 R 544404 CDS YP_003077933.1 254793096 8216602 complement(2076057..2076656) 1 NC_013008.1 Ail/Lom family protein 2076656 8216602 ECSP_2036 Escherichia coli O157:H7 str. TW14359 Ail/Lom family protein YP_003077933.1 2076057 R 544404 CDS YP_003077934.1 254793097 8216603 complement(2076724..2079237) 1 NC_013008.1 host specificity protein 2079237 8216603 ECSP_2037 Escherichia coli O157:H7 str. TW14359 host specificity protein YP_003077934.1 2076724 R 544404 CDS YP_003077935.1 254793098 8216604 complement(2079234..2080802) 1 NC_013008.1 host specificity protein 2080802 8216604 ECSP_2038 Escherichia coli O157:H7 str. TW14359 host specificity protein YP_003077935.1 2079234 R 544404 CDS YP_003077936.1 254793099 8216605 complement(2081144..2081725) 1 NC_013008.1 tail assembly protein 2081725 8216605 ECSP_2039 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003077936.1 2081144 R 544404 CDS YP_003077937.1 254793100 8216606 complement(2081722..2082465) 1 NC_013008.1 tail assembly protein 2082465 8216606 ECSP_2040 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003077937.1 2081722 R 544404 CDS YP_003077938.1 254793101 8216607 complement(2082476..2083174) 1 NC_013008.1 phage minor tail protein L 2083174 8216607 ECSP_2041 Escherichia coli O157:H7 str. TW14359 phage minor tail protein L YP_003077938.1 2082476 R 544404 CDS YP_003077939.1 254793102 8216608 complement(2083174..2083515) 1 NC_013008.1 minor tail protein 2083515 8216608 ECSP_2042 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077939.1 2083174 R 544404 CDS YP_003077940.1 254793103 8216609 complement(2083508..2086750) 1 NC_013008.1 tail length tape measure protein 2086750 8216609 ECSP_2043 Escherichia coli O157:H7 str. TW14359 tail length tape measure protein YP_003077940.1 2083508 R 544404 CDS YP_003077941.1 254793104 8216610 complement(2086802..2087005) 1 NC_013008.1 hypothetical protein 2087005 8216610 ECSP_2044 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077941.1 2086802 R 544404 CDS YP_003077942.1 254793105 8216611 complement(2087107..2087481) 1 NC_013008.1 tail assembly chaperone 2087481 8216611 ECSP_2045 Escherichia coli O157:H7 str. TW14359 tail assembly chaperone YP_003077942.1 2087107 R 544404 CDS YP_003077943.1 254793106 8216612 complement(2087487..2088203) 1 NC_013008.1 major tail subunit 2088203 8216612 ECSP_2046 Escherichia coli O157:H7 str. TW14359 major tail subunit YP_003077943.1 2087487 R 544404 CDS YP_003077944.1 254793107 8216613 complement(2088262..2088606) 1 NC_013008.1 hypothetical protein 2088606 8216613 ECSP_2047 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077944.1 2088262 R 544404 CDS YP_003077945.1 254793108 8216614 complement(2088603..2089049) 1 NC_013008.1 hypothetical protein 2089049 8216614 ECSP_2048 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077945.1 2088603 R 544404 CDS YP_003077946.1 254793109 8216615 complement(2089046..2089396) 1 NC_013008.1 head-tail adaptor 2089396 8216615 ECSP_2049 Escherichia coli O157:H7 str. TW14359 head-tail adaptor YP_003077946.1 2089046 R 544404 CDS YP_003077947.1 254793110 8216616 complement(2089406..2089732) 1 NC_013008.1 hypothetical protein 2089732 8216616 ECSP_2050 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077947.1 2089406 R 544404 CDS YP_003077948.1 254793111 8216617 complement(2089729..2090466) 1 NC_013008.1 portal protein 2090466 8216617 ECSP_2051 Escherichia coli O157:H7 str. TW14359 portal protein YP_003077948.1 2089729 R 544404 CDS YP_003077949.1 254793112 8216618 complement(2090463..2091767) 1 NC_013008.1 portal protein 2091767 8216618 ECSP_2052 Escherichia coli O157:H7 str. TW14359 portal protein YP_003077949.1 2090463 R 544404 CDS YP_003077950.1 254793113 8216619 complement(2092039..2092536) 1 NC_013008.1 major head protein/prohead protease 2092536 8216619 ECSP_2053 Escherichia coli O157:H7 str. TW14359 major head protein/prohead protease YP_003077950.1 2092039 R 544404 CDS YP_003077951.1 254793114 8216620 complement(2092538..2092945) 1 NC_013008.1 hypothetical protein 2092945 8216620 ECSP_2054 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077951.1 2092538 R 544404 CDS YP_003077952.1 254793115 8216621 complement(2092950..2093156) 1 NC_013008.1 hypothetical protein 2093156 8216621 ECSP_2055 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077952.1 2092950 R 544404 CDS YP_003077953.1 254793116 8216622 complement(2093604..2095454) 1 NC_013008.1 hypothetical protein 2095454 8216622 ECSP_2056 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077953.1 2093604 R 544404 CDS YP_003077954.1 254793117 8216623 complement(2095932..2096426) 1 NC_013008.1 hypothetical protein 2096426 8216623 ECSP_2057 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077954.1 2095932 R 544404 CDS YP_003077955.1 254793118 8216626 complement(2096814..2097527) 1 NC_013008.1 AraC family transcriptional regulator 2097527 8216626 ECSP_2060 Escherichia coli O157:H7 str. TW14359 AraC family transcriptional regulator YP_003077955.1 2096814 R 544404 CDS YP_003077956.1 254793119 8216627 complement(2097663..2097947) 1 NC_013008.1 hypothetical protein 2097947 8216627 ECSP_2061 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077956.1 2097663 R 544404 CDS YP_003077957.1 254793120 8216628 complement(2098085..2098639) 1 NC_013008.1 hypothetical protein 2098639 8216628 ECSP_2062 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077957.1 2098085 R 544404 CDS YP_003077958.1 254793121 8216629 complement(2098702..2099007) 1 NC_013008.1 endonuclease encoded within prophage CP-933O 2099007 8216629 ECSP_2063 Escherichia coli O157:H7 str. TW14359 endonuclease encoded within prophage CP-933O YP_003077958.1 2098702 R 544404 CDS YP_003077959.1 254793122 8216630 complement(2099020..2100069) 1 NC_013008.1 hypothetical protein 2100069 8216630 ECSP_2064 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077959.1 2099020 R 544404 CDS YP_003077960.1 254793123 8216631 complement(2100071..2100343) 1 NC_013008.1 hypothetical protein 2100343 8216631 ECSP_2065 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077960.1 2100071 R 544404 CDS YP_003077961.1 254793124 8216632 complement(2100465..2100809) 1 NC_013008.1 hypothetical protein 2100809 8216632 ECSP_2066 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077961.1 2100465 R 544404 CDS YP_003077962.1 254793125 8216633 complement(2101375..2101932) 1 NC_013008.1 hypothetical protein 2101932 8216633 ECSP_2067 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077962.1 2101375 R 544404 CDS YP_003077963.1 254793126 8216634 complement(2102280..2102591) 1 NC_013008.1 hypothetical protein 2102591 8216634 ECSP_2068 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077963.1 2102280 R 544404 CDS YP_003077964.1 254793127 8216635 complement(2103122..2103838) 1 NC_013008.1 hypothetical protein 2103838 8216635 ECSP_2069 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077964.1 2103122 R 544404 CDS YP_003077965.1 254793128 8216636 complement(2103872..2104333) 1 NC_013008.1 hypothetical protein 2104333 8216636 ECSP_2070 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077965.1 2103872 R 544404 CDS YP_003077966.1 254793129 8216637 complement(2104326..2105369) 1 NC_013008.1 hypothetical protein 2105369 8216637 ECSP_2071 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077966.1 2104326 R 544404 CDS YP_003077967.1 254793130 8216638 complement(2105438..2105863) 1 NC_013008.1 hypothetical protein 2105863 8216638 ECSP_2072 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077967.1 2105438 R 544404 CDS YP_003077968.1 254793131 8216639 complement(2105847..2106089) 1 NC_013008.1 hypothetical protein 2106089 8216639 ECSP_2073 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077968.1 2105847 R 544404 CDS YP_003077969.1 254793132 8216640 2106181..2106819 1 NC_013008.1 repressor protein encoded within prophage CP-933O 2106819 8216640 ECSP_2074 Escherichia coli O157:H7 str. TW14359 repressor protein encoded within prophage CP-933O YP_003077969.1 2106181 D 544404 CDS YP_003077970.1 254793133 8216641 2107031..2107264 1 NC_013008.1 hypothetical protein 2107264 8216641 ECSP_2075 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077970.1 2107031 D 544404 CDS YP_003077971.1 254793134 8216642 2107276..2107914 1 NC_013008.1 hypothetical protein 2107914 8216642 ECSP_2076 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077971.1 2107276 D 544404 CDS YP_003077972.1 254793135 8216643 complement(2107915..2108124) 1 NC_013008.1 hypothetical protein 2108124 8216643 ECSP_2077 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077972.1 2107915 R 544404 CDS YP_003077973.1 254793136 8216644 complement(2108173..2108433) 1 NC_013008.1 hypothetical protein 2108433 8216644 ECSP_2078 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077973.1 2108173 R 544404 CDS YP_003077974.1 254793137 8216645 2108584..2108877 1 NC_013008.1 similar to division inhibition protein DicB within CP-933O; division inhibition protein DicB-like protein within CP-933O 2108877 8216645 ECSP_2079 Escherichia coli O157:H7 str. TW14359 division inhibition protein DicB-like protein within CP-933O YP_003077974.1 2108584 D 544404 CDS YP_003077975.1 254793138 8216646 2109155..2110399 1 NC_013008.1 exonuclease 2110399 8216646 ECSP_2080 Escherichia coli O157:H7 str. TW14359 exonuclease YP_003077975.1 2109155 D 544404 CDS YP_003077976.1 254793139 8216647 2110510..2110932 1 NC_013008.1 integrase 2110932 8216647 ECSP_2081 Escherichia coli O157:H7 str. TW14359 integrase YP_003077976.1 2110510 D 544404 CDS YP_003077977.1 254793140 8216648 2111017..2111352 1 NC_013008.1 hypothetical protein 2111352 8216648 ECSP_2082 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077977.1 2111017 D 544404 CDS YP_003077978.1 254793141 8216650 2112294..2112695 1 NC_013008.1 transposase 2112695 8216650 ECSP_2084 Escherichia coli O157:H7 str. TW14359 transposase YP_003077978.1 2112294 D 544404 CDS YP_003077979.1 254793142 8216651 2112692..2113039 1 NC_013008.1 transposase 2113039 8216651 ECSP_2085 Escherichia coli O157:H7 str. TW14359 transposase YP_003077979.1 2112692 D 544404 CDS YP_003077980.1 254793143 8216652 2113089..2114627 1 NC_013008.1 transposase ISEc8 2114627 8216652 ECSP_2086 Escherichia coli O157:H7 str. TW14359 transposase ISEc8 YP_003077980.1 2113089 D 544404 CDS YP_003077981.1 254793144 8216653 complement(2114638..2115060) 1 NC_013008.1 transposase within CP-933O 2115060 8216653 ECSP_2087 Escherichia coli O157:H7 str. TW14359 transposase within CP-933O YP_003077981.1 2114638 R 544404 CDS YP_003077982.1 254793145 8216654 complement(2115210..2115860) 1 NC_013008.1 non-LEE-encoded type III effector 2115860 nleG7 8216654 nleG7 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003077982.1 2115210 R 544404 CDS YP_003077983.1 254793146 8216655 complement(2116571..2117146) 1 NC_013008.1 hypothetical protein 2117146 8216655 ECSP_2089 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077983.1 2116571 R 544404 CDS YP_003077984.1 254793147 8216656 complement(2117260..2117529) 1 NC_013008.1 hypothetical protein 2117529 8216656 ECSP_2090 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077984.1 2117260 R 544404 CDS YP_003077985.1 254793148 8216657 complement(2117531..2118754) 1 NC_013008.1 tail fiber protein 2118754 8216657 ECSP_2091 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003077985.1 2117531 R 544404 CDS YP_003077986.1 254793149 8216658 complement(2118819..2119418) 1 NC_013008.1 Ail/Lom family protein 2119418 8216658 ECSP_2092 Escherichia coli O157:H7 str. TW14359 Ail/Lom family protein YP_003077986.1 2118819 R 544404 CDS YP_003077987.1 254793150 8216659 complement(2119704..2122964) 1 NC_013008.1 tail component of prophage CP-933O 2122964 8216659 ECSP_2093 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933O YP_003077987.1 2119704 R 544404 CDS YP_003077988.1 254793151 8216660 complement(2123152..2123589) 1 NC_013008.1 minor tail protein 2123589 8216660 ECSP_2094 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077988.1 2123152 R 544404 CDS YP_003077989.1 254793152 8216661 complement(2123589..2123930) 1 NC_013008.1 minor tail protein 2123930 8216661 ECSP_2095 Escherichia coli O157:H7 str. TW14359 minor tail protein YP_003077989.1 2123589 R 544404 CDS YP_003077990.1 254793153 8216662 complement(2123923..2127165) 1 NC_013008.1 tail component of cryptic prophage CP-933P 2127165 8216662 ECSP_2096 Escherichia coli O157:H7 str. TW14359 tail component of cryptic prophage CP-933P YP_003077990.1 2123923 R 544404 CDS YP_003077991.1 254793154 8216663 complement(2127213..2127494) 1 NC_013008.1 tail assembly protein of cryptic prophage CP-933P 2127494 8216663 ECSP_2097 Escherichia coli O157:H7 str. TW14359 tail assembly protein of cryptic prophage CP-933P YP_003077991.1 2127213 R 544404 CDS YP_003077992.1 254793155 8216664 complement(2127518..2127892) 1 NC_013008.1 tail assembly protein of cryptic prophage CP-933P 2127892 8216664 ECSP_2098 Escherichia coli O157:H7 str. TW14359 tail assembly protein of cryptic prophage CP-933P YP_003077992.1 2127518 R 544404 CDS YP_003077993.1 254793156 8216665 complement(2127907..2128623) 1 NC_013008.1 tail component of cryptic prophage CP-933P 2128623 8216665 ECSP_2099 Escherichia coli O157:H7 str. TW14359 tail component of cryptic prophage CP-933P YP_003077993.1 2127907 R 544404 CDS YP_003077994.1 254793157 8216666 complement(2128689..2129033) 1 NC_013008.1 structural component of cryptic prophage CP-933P 2129033 8216666 ECSP_2100 Escherichia coli O157:H7 str. TW14359 structural component of cryptic prophage CP-933P YP_003077994.1 2128689 R 544404 CDS YP_003077995.1 254793158 8216667 complement(2129030..2129476) 1 NC_013008.1 hypothetical protein 2129476 8216667 ECSP_2101 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077995.1 2129030 R 544404 CDS YP_003077996.1 254793159 8216668 complement(2129473..2129823) 1 NC_013008.1 head-tail adaptor protein 2129823 8216668 ECSP_2102 Escherichia coli O157:H7 str. TW14359 head-tail adaptor protein YP_003077996.1 2129473 R 544404 CDS YP_003077997.1 254793160 8216669 complement(2129833..2130159) 1 NC_013008.1 hypothetical protein 2130159 8216669 ECSP_2103 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077997.1 2129833 R 544404 CDS YP_003077998.1 254793161 8216670 complement(2130162..2132741) 1 NC_013008.1 hypothetical protein 2132741 8216670 ECSP_2104 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077998.1 2130162 R 544404 CDS YP_003077999.1 254793162 8216671 complement(2132953..2134890) 1 NC_013008.1 hypothetical protein 2134890 8216671 ECSP_2105 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003077999.1 2132953 R 544404 CDS YP_003078000.1 254793163 8216672 complement(2134954..2136615) 1 NC_013008.1 terminase large subunit 2136615 8216672 ECSP_2106 Escherichia coli O157:H7 str. TW14359 terminase large subunit YP_003078000.1 2134954 R 544404 CDS YP_003078001.1 254793164 8216673 complement(2136612..2137175) 1 NC_013008.1 terminase subunit 2137175 8216673 ECSP_2107 Escherichia coli O157:H7 str. TW14359 terminase subunit YP_003078001.1 2136612 R 544404 CDS YP_003078002.1 254793165 8216674 complement(2137467..2137832) 1 NC_013008.1 HNH endonuclease 2137832 8216674 ECSP_2108 Escherichia coli O157:H7 str. TW14359 HNH endonuclease YP_003078002.1 2137467 R 544404 CDS YP_003078003.1 254793166 8216675 complement(2138464..2138931) 1 NC_013008.1 bacteriophage lysis protein 2138931 8216675 ECSP_2109 Escherichia coli O157:H7 str. TW14359 bacteriophage lysis protein YP_003078003.1 2138464 R 544404 CDS YP_003078004.1 254793167 8216676 complement(2139085..2139654) 1 NC_013008.1 antirepressor protein 2139654 8216676 ECSP_2110 Escherichia coli O157:H7 str. TW14359 antirepressor protein YP_003078004.1 2139085 R 544404 CDS YP_003078005.1 254793168 8216677 complement(2139925..2140458) 1 NC_013008.1 endolysin encoded by cryptic prophage CP-933P 2140458 8216677 ECSP_2111 Escherichia coli O157:H7 str. TW14359 endolysin encoded by cryptic prophage CP-933P YP_003078005.1 2139925 R 544404 CDS YP_003078006.1 254793169 8216678 complement(2140509..2140853) 1 NC_013008.1 hypothetical protein 2140853 8216678 ECSP_2112 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078006.1 2140509 R 544404 CDS YP_003078007.1 254793170 8216679 complement(2140858..2141064) 1 NC_013008.1 holin protein encoded by cryptic prophage CP-933P 2141064 8216679 ECSP_2113 Escherichia coli O157:H7 str. TW14359 holin protein encoded by cryptic prophage CP-933P YP_003078007.1 2140858 R 544404 CDS YP_003078008.1 254793171 8216680 complement(2141513..2143363) 1 NC_013008.1 hypothetical protein 2143363 8216680 ECSP_2114 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078008.1 2141513 R 544404 CDS YP_003078009.1 254793172 8216681 complement(2143412..2143540) 1 NC_013008.1 hypothetical protein 2143540 8216681 ECSP_2115 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078009.1 2143412 R 544404 CDS YP_003078010.1 254793173 8216682 complement(2143678..2143845) 1 NC_013008.1 hypothetical protein 2143845 8216682 ECSP_2116 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078010.1 2143678 R 544404 CDS YP_003078011.1 254793174 8216683 complement(2143842..2144270) 1 NC_013008.1 hypothetical protein 2144270 8216683 ECSP_2117 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078011.1 2143842 R 544404 CDS YP_003078012.1 254793175 8216687 complement(2144908..2145597) 1 NC_013008.1 Q antiterminator encoded by prophage CP-933P 2145597 8216687 ECSP_2121 Escherichia coli O157:H7 str. TW14359 Q antiterminator encoded by prophage CP-933P YP_003078012.1 2144908 R 544404 CDS YP_003078013.1 254793176 8216688 complement(2145594..2145953) 1 NC_013008.1 endonuclease encoded by cryptic prophage CP-933P 2145953 8216688 ECSP_2122 Escherichia coli O157:H7 str. TW14359 endonuclease encoded by cryptic prophage CP-933P YP_003078013.1 2145594 R 544404 CDS YP_003078014.1 254793177 8216689 complement(2145966..2147015) 1 NC_013008.1 hypothetical protein 2147015 8216689 ECSP_2123 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078014.1 2145966 R 544404 CDS YP_003078015.1 254793178 8216690 complement(2147017..2147295) 1 NC_013008.1 hypothetical protein 2147295 8216690 ECSP_2124 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078015.1 2147017 R 544404 CDS YP_003078016.1 254793179 8216691 complement(2147463..2147675) 1 NC_013008.1 cell killing protein encoded within cryptic prophage CP-933P 2147675 mokP 8216691 mokP Escherichia coli O157:H7 str. TW14359 cell killing protein encoded within cryptic prophage CP-933P YP_003078016.1 2147463 R 544404 CDS YP_003078017.1 254793180 8216692 complement(2147864..2147968) 1 NC_013008.1 hypothetical protein 2147968 8216692 ECSP_2126 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078017.1 2147864 R 544404 CDS YP_003078018.1 254793181 8216693 complement(2148084..2148728) 1 NC_013008.1 hypothetical protein 2148728 8216693 ECSP_2127 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078018.1 2148084 R 544404 CDS YP_003078019.1 254793182 8216694 complement(2148725..2149120) 1 NC_013008.1 exclusion protein ren of cryptic prophage CP-933P 2149120 renP 8216694 renP Escherichia coli O157:H7 str. TW14359 exclusion protein ren of cryptic prophage CP-933P YP_003078019.1 2148725 R 544404 CDS YP_003078020.1 254793183 8216696 complement(2149931..2150671) 1 NC_013008.1 replication protein 2150671 8216696 ECSP_2130 Escherichia coli O157:H7 str. TW14359 replication protein YP_003078020.1 2149931 R 544404 CDS YP_003078021.1 254793184 8216697 complement(2150678..2151640) 1 NC_013008.1 hypothetical protein 2151640 8216697 ECSP_2131 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078021.1 2150678 R 544404 CDS YP_003078022.1 254793185 8216698 complement(2151663..2152088) 1 NC_013008.1 hypothetical protein 2152088 8216698 ECSP_2132 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078022.1 2151663 R 544404 CDS YP_003078023.1 254793186 8216699 complement(2152085..2152387) 1 NC_013008.1 hypothetical protein 2152387 8216699 ECSP_2133 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078023.1 2152085 R 544404 CDS YP_003078024.1 254793187 8216700 2152422..2152856 1 NC_013008.1 repressor protein encoded by cryptic prophage CP-933P 2152856 8216700 ECSP_2134 Escherichia coli O157:H7 str. TW14359 repressor protein encoded by cryptic prophage CP-933P YP_003078024.1 2152422 D 544404 CDS YP_003078025.1 254793188 8216701 2153070..2153348 1 NC_013008.1 plasmid stabilization system protein 2153348 8216701 ECSP_2135 Escherichia coli O157:H7 str. TW14359 plasmid stabilization system protein YP_003078025.1 2153070 D 544404 CDS YP_003078026.1 254793189 8216702 2153644..2154000 1 NC_013008.1 hypothetical protein 2154000 8216702 ECSP_2136 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078026.1 2153644 D 544404 CDS YP_003078027.1 254793190 8216703 2154072..2154290 1 NC_013008.1 hypothetical protein 2154290 8216703 ECSP_2137 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078027.1 2154072 D 544404 CDS YP_003078028.1 254793191 8216704 2154754..2155047 1 NC_013008.1 inhibitor of cell division encoded by cryptic prophage CP-933P 2155047 8216704 ECSP_2138 Escherichia coli O157:H7 str. TW14359 inhibitor of cell division encoded by cryptic prophage CP-933P YP_003078028.1 2154754 D 544404 CDS YP_003078029.1 254793192 8216705 2155044..2155235 1 NC_013008.1 hypothetical protein 2155235 8216705 ECSP_2139 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078029.1 2155044 D 544404 CDS YP_003078030.1 254793193 8216706 2155328..2156458 1 NC_013008.1 hypothetical protein 2156458 8216706 ECSP_2140 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078030.1 2155328 D 544404 CDS YP_003078031.1 254793194 8216707 2156464..2156790 1 NC_013008.1 transposase 2156790 8216707 ECSP_2141 Escherichia coli O157:H7 str. TW14359 transposase YP_003078031.1 2156464 D 544404 CDS YP_003078032.1 254793195 8216708 2156787..2157677 1 NC_013008.1 transposase 2157677 8216708 ECSP_2142 Escherichia coli O157:H7 str. TW14359 transposase YP_003078032.1 2156787 D 544404 CDS YP_003078033.1 254793196 8216709 2157730..2159112 1 NC_013008.1 exodeoxyribonuclease encoded by cryptic prophage CP-933P 2159112 8216709 ECSP_2143 Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease encoded by cryptic prophage CP-933P YP_003078033.1 2157730 D 544404 CDS YP_003078034.1 254793197 8216710 2159185..2159436 1 NC_013008.1 excisionase of cryptic prophage CP-933P 2159436 xisP 8216710 xisP Escherichia coli O157:H7 str. TW14359 excisionase of cryptic prophage CP-933P YP_003078034.1 2159185 D 544404 CDS YP_003078035.1 254793198 8216711 2159674..2160162 1 NC_013008.1 site-specific recombinase, phage integrase family 2160162 8216711 ECSP_2145 Escherichia coli O157:H7 str. TW14359 site-specific recombinase, phage integrase family YP_003078035.1 2159674 D 544404 CDS YP_003078036.1 254793199 8216712 complement(2160425..2160751) 1 NC_013008.1 hypothetical protein 2160751 ynfA 8216712 ynfA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078036.1 2160425 R 544404 CDS YP_003078037.1 254793200 8216713 2160886..2161227 1 NC_013008.1 hypothetical protein 2161227 ynfB 8216713 ynfB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078037.1 2160886 D 544404 CDS YP_003078038.1 254793201 8216714 2161262..2161822 1 NC_013008.1 spermidine N1-acetyltransferase 2161822 speG 8216714 speG Escherichia coli O157:H7 str. TW14359 spermidine N1-acetyltransferase YP_003078038.1 2161262 D 544404 CDS YP_003078039.1 254793202 8216715 complement(2161825..2162535) 1 NC_013008.1 hypothetical protein 2162535 ynfC 8216715 ynfC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078039.1 2161825 R 544404 CDS YP_003078040.1 254793203 8216716 2162643..2162948 1 NC_013008.1 hypothetical protein 2162948 ynfD 8216716 ynfD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078040.1 2162643 D 544404 CDS YP_003078041.1 254793204 8216717 2163147..2165573 1 NC_013008.1 oxidoreductase subunit 2165573 ynfE 8216717 ynfE Escherichia coli O157:H7 str. TW14359 oxidoreductase subunit YP_003078041.1 2163147 D 544404 CDS YP_003078042.1 254793205 8216718 2165634..2168057 1 NC_013008.1 oxidoreductase subunit 2168057 ynfF 8216718 ynfF Escherichia coli O157:H7 str. TW14359 oxidoreductase subunit YP_003078042.1 2165634 D 544404 CDS YP_003078043.1 254793206 8216719 2168068..2168685 1 NC_013008.1 oxidoreductase, Fe-S subunit 2168685 ynfG 8216719 ynfG Escherichia coli O157:H7 str. TW14359 oxidoreductase, Fe-S subunit YP_003078043.1 2168068 D 544404 CDS YP_003078044.1 254793207 8216720 2168687..2169541 1 NC_013008.1 oxidoreductase, membrane subunit 2169541 ynfH 8216720 ynfH Escherichia coli O157:H7 str. TW14359 oxidoreductase, membrane subunit YP_003078044.1 2168687 D 544404 CDS YP_003078045.1 254793208 8216721 2169584..2170198 1 NC_013008.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 2170198 dmsD 8216721 dmsD Escherichia coli O157:H7 str. TW14359 twin-argninine leader-binding protein DmsD YP_003078045.1 2169584 D 544404 CDS YP_003078046.1 254793209 8216722 2170392..2171648 1 NC_013008.1 voltage-gated ClC-type chloride channel ClcB 2171648 clcB 8216722 clcB Escherichia coli O157:H7 str. TW14359 voltage-gated ClC-type chloride channel ClcB YP_003078046.1 2170392 D 544404 CDS YP_003078047.1 254793210 8216723 complement(2171601..2172296) 1 NC_013008.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 2172296 ynfK 8216723 ynfK Escherichia coli O157:H7 str. TW14359 dithiobiotin synthetase YP_003078047.1 2171601 R 544404 CDS YP_003078048.1 254793211 8216724 complement(2172421..2173641) 1 NC_013008.1 DNA-binding transcriptional repressor 2173641 dgsA 8216724 dgsA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor YP_003078048.1 2172421 R 544404 CDS YP_003078049.1 254793212 8216725 complement(2173776..2174669) 1 NC_013008.1 DNA-binding transcriptional regulator 2174669 ynfL 8216725 ynfL Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078049.1 2173776 R 544404 CDS YP_003078050.1 254793213 8216726 2174776..2176029 1 NC_013008.1 transporter 2176029 ynfM 8216726 ynfM Escherichia coli O157:H7 str. TW14359 transporter YP_003078050.1 2174776 D 544404 CDS YP_003078051.1 254793214 8216727 2176453..2176761 1 NC_013008.1 required for growth and survival under moderately acid conditions; acid shock protein 2176761 asr 8216727 asr Escherichia coli O157:H7 str. TW14359 acid shock protein YP_003078051.1 2176453 D 544404 CDS YP_003078052.1 254793215 8216728 2177037..2177858 1 NC_013008.1 peptidase 2177858 ydgD 8216728 ydgD Escherichia coli O157:H7 str. TW14359 peptidase YP_003078052.1 2177037 D 544404 CDS YP_003078053.1 254793216 8216729 complement(2177897..2178226) 1 NC_013008.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 2178226 mdtI 8216729 mdtI Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein MdtI YP_003078053.1 2177897 R 544404 CDS YP_003078054.1 254793217 8216730 complement(2178213..2178578) 1 NC_013008.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 2178578 mdtJ 8216730 mdtJ Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein MdtJ YP_003078054.1 2178213 R 544404 CDS YP_003078055.1 254793218 8216731 2178990..2180024 1 NC_013008.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 2180024 tqsA 8216731 tqsA Escherichia coli O157:H7 str. TW14359 transport protein YP_003078055.1 2178990 D 544404 CDS YP_003078056.1 254793219 8216732 complement(2180049..2181437) 1 NC_013008.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 2181437 pntB 8216732 pntB Escherichia coli O157:H7 str. TW14359 pyridine nucleotide transhydrogenase YP_003078056.1 2180049 R 544404 CDS YP_003078057.1 254793220 8216733 complement(2181448..2182980) 1 NC_013008.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 2182980 pntA 8216733 pntA Escherichia coli O157:H7 str. TW14359 NAD(P) transhydrogenase subunit alpha YP_003078057.1 2181448 R 544404 CDS YP_003078058.1 254793221 8216734 2183504..2184448 1 NC_013008.1 hypothetical protein 2184448 ydgH 8216734 ydgH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078058.1 2183504 D 544404 CDS YP_003078059.1 254793222 8216735 2184634..2186016 1 NC_013008.1 arginine/ornithine antiporter transporter 2186016 ydgI 8216735 ydgI Escherichia coli O157:H7 str. TW14359 arginine/ornithine antiporter transporter YP_003078059.1 2184634 D 544404 CDS YP_003078060.1 254793223 8216736 2186053..2186775 1 NC_013008.1 short chain dehydrogenase 2186775 folM 8216736 folM Escherichia coli O157:H7 str. TW14359 short chain dehydrogenase YP_003078060.1 2186053 D 544404 CDS YP_003078061.1 254793224 8216737 complement(2186772..2187107) 1 NC_013008.1 hypothetical protein 2187107 ydgC 8216737 ydgC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078061.1 2186772 R 544404 CDS YP_003078062.1 254793225 8216738 2187236..2187955 1 NC_013008.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 2187955 rstA 8216738 rstA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator RstA YP_003078062.1 2187236 D 544404 CDS YP_003078063.1 254793226 8216739 2187959..2189260 1 NC_013008.1 sensor protein RstB 2189260 rstB 8216739 rstB Escherichia coli O157:H7 str. TW14359 sensor protein RstB YP_003078063.1 2187959 D 544404 CDS YP_003078064.1 254793227 8216740 2189336..2190265 1 NC_013008.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 2190265 tus 8216740 tus Escherichia coli O157:H7 str. TW14359 DNA replication terminus site-binding protein YP_003078064.1 2189336 D 544404 CDS YP_003078065.1 254793228 8216741 complement(2190262..2191665) 1 NC_013008.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 2191665 fumC 8216741 fumC Escherichia coli O157:H7 str. TW14359 fumarate hydratase YP_003078065.1 2190262 R 544404 CDS YP_003078066.1 254793229 8216742 complement(2191808..2193454) 1 NC_013008.1 fumarate hydratase 2193454 fumA 8216742 fumA Escherichia coli O157:H7 str. TW14359 fumarate hydratase YP_003078066.1 2191808 R 544404 CDS YP_003078067.1 254793230 8216743 2193653..2194828 1 NC_013008.1 mannose-6-phosphate isomerase 2194828 manA 8216743 manA Escherichia coli O157:H7 str. TW14359 mannose-6-phosphate isomerase YP_003078067.1 2193653 D 544404 CDS YP_003078068.1 254793231 8216744 2194929..2196437 1 NC_013008.1 hypothetical protein 2196437 ydgA 8216744 ydgA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078068.1 2194929 D 544404 CDS YP_003078069.1 254793232 8216745 complement(2196718..2197728) 1 NC_013008.1 hypothetical protein 2197728 8216745 ECSP_2179 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078069.1 2196718 R 544404 CDS YP_003078070.1 254793233 8216746 complement(2197785..2199158) 1 NC_013008.1 glucuronide transporter 2199158 uidB 8216746 uidB Escherichia coli O157:H7 str. TW14359 glucuronide transporter YP_003078070.1 2197785 R 544404 CDS YP_003078071.1 254793234 8216748 complement(2201359..2201949) 1 NC_013008.1 DNA-binding transcriptional repressor 2201949 uidR 8216748 uidR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor YP_003078071.1 2201359 R 544404 CDS YP_003078072.1 254793235 8216749 complement(2202178..2202945) 1 NC_013008.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 2202945 hdhA 8216749 hdhA Escherichia coli O157:H7 str. TW14359 7-alpha-hydroxysteroid dehydrogenase YP_003078072.1 2202178 R 544404 CDS YP_003078073.1 254793236 8216750 complement(2203057..2204085) 1 NC_013008.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 2204085 malI 8216750 malI Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor MalI YP_003078073.1 2203057 R 544404 CDS YP_003078074.1 254793237 8216751 2204260..2205852 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 2205852 malX 8216751 malX Escherichia coli O157:H7 str. TW14359 bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_003078074.1 2204260 D 544404 CDS YP_003078075.1 254793238 8216752 2205862..2207034 1 NC_013008.1 bifunctional beta-cystathionase, PLP-dependent and regulator of maltose regulon 2207034 malY 8216752 malY Escherichia coli O157:H7 str. TW14359 bifunctional beta-cystathionase, PLP-dependent and regulator of maltose regulon YP_003078075.1 2205862 D 544404 CDS YP_003078076.1 254793239 8216753 2207138..2208139 1 NC_013008.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 2208139 add 8216753 add Escherichia coli O157:H7 str. TW14359 adenosine deaminase YP_003078076.1 2207138 D 544404 CDS YP_003078077.1 254793240 8216754 complement(2208175..2209215) 1 NC_013008.1 oxidoreductase 2209215 ydgJ 8216754 ydgJ Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078077.1 2208175 R 544404 CDS YP_003078078.1 254793241 8216755 2209458..2209583 1 NC_013008.1 beta-lactam resistance membrane protein 2209583 blr 8216755 blr Escherichia coli O157:H7 str. TW14359 beta-lactam resistance membrane protein YP_003078078.1 2209458 D 544404 CDS YP_003078079.1 254793242 8216756 2209856..2210071 1 NC_013008.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 2210071 8216756 ECSP_2190 Escherichia coli O157:H7 str. TW14359 oriC-binding nucleoid-associated protein YP_003078079.1 2209856 D 544404 CDS YP_003078080.1 254793243 8216757 2210157..2210597 1 NC_013008.1 hypothetical protein 2210597 ydgK 8216757 ydgK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078080.1 2210157 D 544404 CDS YP_003078081.1 254793244 8216758 2210674..2211255 1 NC_013008.1 Na(+)-translocating NADH-quinone reductase subunit E 2211255 rsxA 8216758 rsxA Escherichia coli O157:H7 str. TW14359 Na(+)-translocating NADH-quinone reductase subunit E YP_003078081.1 2210674 D 544404 CDS YP_003078082.1 254793245 8216759 2211255..2211833 1 NC_013008.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 2211833 rsxB 8216759 rsxB Escherichia coli O157:H7 str. TW14359 electron transport complex protein RnfB YP_003078082.1 2211255 D 544404 CDS YP_003078083.1 254793246 8216760 2211826..2214144 1 NC_013008.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 2214144 rsxC 8216760 rsxC Escherichia coli O157:H7 str. TW14359 electron transport complex protein RnfC YP_003078083.1 2211826 D 544404 CDS YP_003078084.1 254793247 8216761 2214145..2215203 1 NC_013008.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 2215203 rnfD 8216761 rnfD Escherichia coli O157:H7 str. TW14359 electron transport complex protein RnfD YP_003078084.1 2214145 D 544404 CDS YP_003078085.1 254793248 8216762 2215207..2215827 1 NC_013008.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 2215827 rsxG 8216762 rsxG Escherichia coli O157:H7 str. TW14359 electron transport complex protein RnfG YP_003078085.1 2215207 D 544404 CDS YP_003078086.1 254793249 8216763 2215831..2216526 1 NC_013008.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 2216526 rsxE 8216763 rsxE Escherichia coli O157:H7 str. TW14359 electron transport complex RsxE subunit YP_003078086.1 2215831 D 544404 CDS YP_003078087.1 254793250 8216764 2216526..2217161 1 NC_013008.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 2217161 nth 8216764 nth Escherichia coli O157:H7 str. TW14359 endonuclease III YP_003078087.1 2216526 D 544404 CDS YP_003078088.1 254793251 8216765 2217772..2219274 1 NC_013008.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 2219274 tppB 8216765 tppB Escherichia coli O157:H7 str. TW14359 tripeptide transporter permease YP_003078088.1 2217772 D 544404 CDS YP_003078089.1 254793252 8216766 2219380..2219985 1 NC_013008.1 glutathionine S-transferase 2219985 gst 8216766 gst Escherichia coli O157:H7 str. TW14359 glutathionine S-transferase YP_003078089.1 2219380 D 544404 CDS YP_003078090.1 254793253 8216767 complement(2220029..2220892) 1 NC_013008.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 2220892 pdxY 8216767 pdxY Escherichia coli O157:H7 str. TW14359 pyridoxamine kinase YP_003078090.1 2220029 R 544404 CDS YP_003078091.1 254793254 8216768 complement(2220951..2222225) 1 NC_013008.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2222225 tyrS 8216768 tyrS Escherichia coli O157:H7 str. TW14359 tyrosyl-tRNA synthetase YP_003078091.1 2220951 R 544404 CDS YP_003078092.1 254793255 8216769 complement(2222354..2223010) 1 NC_013008.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2223010 pdxH 8216769 pdxH Escherichia coli O157:H7 str. TW14359 pyridoxamine 5'-phosphate oxidase YP_003078092.1 2222354 R 544404 CDS YP_003078093.1 254793256 8216770 complement(2223069..2223398) 1 NC_013008.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 2223398 ydhA 8216770 ydhA Escherichia coli O157:H7 str. TW14359 lysozyme inhibitor YP_003078093.1 2223069 R 544404 CDS YP_003078094.1 254793257 8216771 complement(2223496..2224605) 1 NC_013008.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 2224605 anmK 8216771 anmK Escherichia coli O157:H7 str. TW14359 anhydro-N-acetylmuramic acid kinase YP_003078094.1 2223496 R 544404 CDS YP_003078095.1 254793258 8216772 2224878..2225345 1 NC_013008.1 outer membrane lipoprotein 2225345 slyB 8216772 slyB Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003078095.1 2224878 D 544404 CDS YP_003078096.1 254793259 8216773 complement(2225392..2225826) 1 NC_013008.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 2225826 slyA 8216773 slyA Escherichia coli O157:H7 str. TW14359 transcriptional regulator SlyA YP_003078096.1 2225392 R 544404 CDS YP_003078097.1 254793260 8216774 2226027..2226263 1 NC_013008.1 inner membrane protein 2226263 ydhI 8216774 ydhI Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078097.1 2226027 D 544404 CDS YP_003078098.1 254793261 8216775 2226266..2227123 1 NC_013008.1 UDP pyrophosphate phosphatase 2227123 ydhJ 8216775 ydhJ Escherichia coli O157:H7 str. TW14359 UDP pyrophosphate phosphatase YP_003078098.1 2226266 D 544404 CDS YP_003078099.1 254793262 8216776 2227123..2229135 1 NC_013008.1 hypothetical protein 2229135 ydhK 8216776 ydhK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078099.1 2227123 D 544404 CDS YP_003078100.1 254793263 8216777 complement(2229136..2229657) 1 NC_013008.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 2229657 sodC 8216777 sodC Escherichia coli O157:H7 str. TW14359 superoxide dismutase YP_003078100.1 2229136 R 544404 CDS YP_003078101.1 254793264 8216778 complement(2229846..2230634) 1 NC_013008.1 oxidoreductase 2230634 ydhF 8216778 ydhF Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078101.1 2229846 R 544404 CDS YP_003078102.1 254793265 8216779 complement(2230683..2230922) 1 NC_013008.1 hypothetical protein 2230922 ydhL 8216779 ydhL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078102.1 2230683 R 544404 CDS YP_003078103.1 254793266 8216780 2231025..2231624 1 NC_013008.1 DNA-binding transcriptional regulator 2231624 ydhM 8216780 ydhM Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078103.1 2231025 D 544404 CDS YP_003078104.1 254793267 8216781 2231661..2232758 1 NC_013008.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 2232758 nemA 8216781 nemA Escherichia coli O157:H7 str. TW14359 N-ethylmaleimide reductase YP_003078104.1 2231661 D 544404 CDS YP_003078105.1 254793268 8216782 2232839..2233246 1 NC_013008.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 2233246 gloA 8216782 gloA Escherichia coli O157:H7 str. TW14359 glyoxalase I YP_003078105.1 2232839 D 544404 CDS YP_003078106.1 254793269 8216783 2233349..2233996 1 NC_013008.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2233996 rnt 8216783 rnt Escherichia coli O157:H7 str. TW14359 ribonuclease T YP_003078106.1 2233349 D 544404 CDS YP_003078107.1 254793270 8216784 2234089..2238705 1 NC_013008.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; ATP-dependent helicase Lhr 2238705 lhr 8216784 lhr Escherichia coli O157:H7 str. TW14359 ATP-dependent helicase Lhr YP_003078107.1 2234089 D 544404 CDS YP_003078108.1 254793271 8216785 complement(2238756..2239103) 1 NC_013008.1 hypothetical protein 2239103 grxD 8216785 grxD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078108.1 2238756 R 544404 CDS YP_003078109.1 254793272 8216786 complement(2239228..2239338) 1 NC_013008.1 hypothetical protein 2239338 8216786 ECSP_2220 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078109.1 2239228 R 544404 CDS YP_003078110.1 254793273 8216787 2239438..2240253 1 NC_013008.1 lipoprotein 2240253 ydhO 8216787 ydhO Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003078110.1 2239438 D 544404 CDS YP_003078111.1 254793274 8216788 2240381..2240962 1 NC_013008.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 2240962 sodB 8216788 sodB Escherichia coli O157:H7 str. TW14359 superoxide dismutase YP_003078111.1 2240381 D 544404 CDS YP_003078112.1 254793275 8216789 complement(2241108..2242277) 1 NC_013008.1 transporter 2242277 ydhP 8216789 ydhP Escherichia coli O157:H7 str. TW14359 transporter YP_003078112.1 2241108 R 544404 CDS YP_003078113.1 254793276 8216790 complement(2242443..2242562) 1 NC_013008.1 membrane protein 2242562 8216790 ECSP_2224 Escherichia coli O157:H7 str. TW14359 membrane protein YP_003078113.1 2242443 R 544404 CDS YP_003078114.1 254793277 8216791 2242831..2243856 1 NC_013008.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 2243856 purR 8216791 purR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor PurR YP_003078114.1 2242831 D 544404 CDS YP_003078115.1 254793278 8216792 complement(2243853..2244785) 1 NC_013008.1 DNA-binding transcriptional regulator 2244785 ydhB 8216792 ydhB Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078115.1 2243853 R 544404 CDS YP_003078116.1 254793279 8216793 2244898..2246109 1 NC_013008.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2246109 ydhC 8216793 ydhC Escherichia coli O157:H7 str. TW14359 inner membrane transport protein YdhC YP_003078116.1 2244898 D 544404 CDS YP_003078117.1 254793280 8216794 2246400..2247548 1 NC_013008.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 2247548 cfa 8216794 cfa Escherichia coli O157:H7 str. TW14359 cyclopropane fatty acyl phospholipid synthase YP_003078117.1 2246400 D 544404 CDS YP_003078118.1 254793281 8216795 complement(2247588..2248229) 1 NC_013008.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2248229 ribC 8216795 ribC Escherichia coli O157:H7 str. TW14359 riboflavin synthase subunit alpha YP_003078118.1 2247588 R 544404 CDS YP_003078119.1 254793282 8216796 2248444..2249817 1 NC_013008.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 2249817 mdtK 8216796 mdtK Escherichia coli O157:H7 str. TW14359 multidrug efflux protein YP_003078119.1 2248444 D 544404 CDS YP_003078120.1 254793283 8216797 complement(2249858..2251114) 1 NC_013008.1 hypothetical protein 2251114 ydhQ 8216797 ydhQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078120.1 2249858 R 544404 CDS YP_003078121.1 254793284 8216800 2251687..2251992 1 NC_013008.1 hypothetical protein 2251992 ydhR 8216800 ydhR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078121.1 2251687 D 544404 CDS YP_003078122.1 254793285 8216801 2252118..2253722 1 NC_013008.1 hypothetical protein 2253722 ydhS 8216801 ydhS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078122.1 2252118 D 544404 CDS YP_003078123.1 254793286 8216802 complement(2253734..2254546) 1 NC_013008.1 hypothetical protein 2254546 ydhT 8216802 ydhT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078123.1 2253734 R 544404 CDS YP_003078124.1 254793287 8216803 complement(2254550..2255335) 1 NC_013008.1 cytochrome 2255335 ydhU 8216803 ydhU Escherichia coli O157:H7 str. TW14359 cytochrome YP_003078124.1 2254550 R 544404 CDS YP_003078125.1 254793288 8216804 complement(2255332..2256000) 1 NC_013008.1 4Fe-4S ferredoxin 2256000 ydhX 8216804 ydhX Escherichia coli O157:H7 str. TW14359 4Fe-4S ferredoxin YP_003078125.1 2255332 R 544404 CDS YP_003078126.1 254793289 8216805 complement(2256064..2256711) 1 NC_013008.1 hypothetical protein 2256711 ydhW 8216805 ydhW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078126.1 2256064 R 544404 CDS YP_003078127.1 254793290 8216806 complement(2256715..2258817) 1 NC_013008.1 oxidoreductase 2258817 ydhV 8216806 ydhV Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078127.1 2256715 R 544404 CDS YP_003078128.1 254793291 8216807 complement(2258838..2259464) 1 NC_013008.1 hypothetical protein 2259464 ydhY 8216807 ydhY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078128.1 2258838 R 544404 CDS YP_003078129.1 254793292 8216808 complement(2259920..2260129) 1 NC_013008.1 hypothetical protein 2260129 ydhZ 8216808 ydhZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078129.1 2259920 R 544404 CDS YP_003078130.1 254793293 8216809 2260686..2262098 1 NC_013008.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2262098 pykF 8216809 pykF Escherichia coli O157:H7 str. TW14359 pyruvate kinase YP_003078130.1 2260686 D 544404 CDS YP_003078131.1 254793294 8216810 2262409..2262645 1 NC_013008.1 murein lipoprotein 2262645 lpp 8216810 lpp Escherichia coli O157:H7 str. TW14359 murein lipoprotein YP_003078131.1 2262409 D 544404 CDS YP_003078132.1 254793295 8216811 complement(2262708..2263712) 1 NC_013008.1 hypothetical protein 2263712 ynhG 8216811 ynhG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078132.1 2262708 R 544404 CDS YP_003078133.1 254793296 8216812 complement(2263861..2264277) 1 NC_013008.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 2264277 sufE 8216812 sufE Escherichia coli O157:H7 str. TW14359 cysteine desufuration protein SufE YP_003078133.1 2263861 R 544404 CDS YP_003078134.1 254793297 8216813 complement(2264290..2265510) 1 NC_013008.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 2265510 sufS 8216813 sufS Escherichia coli O157:H7 str. TW14359 bifunctional cysteine desulfurase/selenocysteine lyase YP_003078134.1 2264290 R 544404 CDS YP_003078135.1 254793298 8216814 complement(2265507..2266778) 1 NC_013008.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 2266778 sufD 8216814 sufD Escherichia coli O157:H7 str. TW14359 cysteine desulfurase activator complex subunit SufD YP_003078135.1 2265507 R 544404 CDS YP_003078136.1 254793299 8216815 complement(2266753..2267499) 1 NC_013008.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase 2267499 sufC 8216815 sufC Escherichia coli O157:H7 str. TW14359 cysteine desulfurase ATPase YP_003078136.1 2266753 R 544404 CDS YP_003078137.1 254793300 8216816 complement(2267509..2268996) 1 NC_013008.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 2268996 sufB 8216816 sufB Escherichia coli O157:H7 str. TW14359 cysteine desulfurase activator complex subunit SufB YP_003078137.1 2267509 R 544404 CDS YP_003078138.1 254793301 8216817 complement(2269005..2269373) 1 NC_013008.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 2269373 sufA 8216817 sufA Escherichia coli O157:H7 str. TW14359 iron-sulfur cluster assembly scaffold protein YP_003078138.1 2269005 R 544404 CDS YP_003078139.1 254793302 8216818 complement(2269922..2270110) 1 NC_013008.1 hypothetical protein 2270110 ydiH 8216818 ydiH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078139.1 2269922 R 544404 CDS YP_003078140.1 254793303 8216819 complement(2270210..2270620) 1 NC_013008.1 hypothetical protein 2270620 ydiI 8216819 ydiI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078140.1 2270210 R 544404 CDS YP_003078141.1 254793304 8216820 complement(2270617..2273673) 1 NC_013008.1 FAD-linked oxidoreductase 2273673 ydiJ 8216820 ydiJ Escherichia coli O157:H7 str. TW14359 FAD-linked oxidoreductase YP_003078141.1 2270617 R 544404 CDS YP_003078142.1 254793305 8216821 2274062..2275174 1 NC_013008.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 2275174 ydiK 8216821 ydiK Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078142.1 2274062 D 544404 CDS YP_003078143.1 254793306 8216822 2275603..2275959 1 NC_013008.1 hypothetical protein 2275959 ydiL 8216822 ydiL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078143.1 2275603 D 544404 CDS YP_003078144.1 254793307 8216823 2276059..2277273 1 NC_013008.1 transporter 2277273 ydiM 8216823 ydiM Escherichia coli O157:H7 str. TW14359 transporter YP_003078144.1 2276059 D 544404 CDS YP_003078145.1 254793308 8216824 2277500..2278765 1 NC_013008.1 transporter 2278765 ydiN 8216824 ydiN Escherichia coli O157:H7 str. TW14359 transporter YP_003078145.1 2277500 D 544404 CDS YP_003078146.1 254793309 8216825 2278777..2279643 1 NC_013008.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2279643 ydiB 8216825 ydiB Escherichia coli O157:H7 str. TW14359 quinate/shikimate dehydrogenase YP_003078146.1 2278777 D 544404 CDS YP_003078147.1 254793310 8216826 2279674..2280432 1 NC_013008.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2280432 aroD 8216826 aroD Escherichia coli O157:H7 str. TW14359 3-dehydroquinate dehydratase YP_003078147.1 2279674 D 544404 CDS YP_003078148.1 254793311 8216827 2280577..2282172 1 NC_013008.1 acyl-CoA transferase 2282172 ydiF 8216827 ydiF Escherichia coli O157:H7 str. TW14359 acyl-CoA transferase YP_003078148.1 2280577 D 544404 CDS YP_003078149.1 254793312 8216828 2282186..2283337 1 NC_013008.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 2283337 ydiO 8216828 ydiO Escherichia coli O157:H7 str. TW14359 acyl-CoA dehydrogenase YP_003078149.1 2282186 D 544404 CDS YP_003078150.1 254793313 8216829 complement(2283380..2284291) 1 NC_013008.1 DNA-binding transcriptional regulator 2284291 ydiP 8216829 ydiP Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078150.1 2283380 R 544404 CDS YP_003078151.1 254793314 8216830 2284607..2285371 1 NC_013008.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 2285371 ydiQ 8216830 ydiQ Escherichia coli O157:H7 str. TW14359 electron transfer flavoprotein YdiQ YP_003078151.1 2284607 D 544404 CDS YP_003078152.1 254793315 8216831 2285391..2286329 1 NC_013008.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2286329 ydiR 8216831 ydiR Escherichia coli O157:H7 str. TW14359 electron transfer flavoprotein subunit YdiR YP_003078152.1 2285391 D 544404 CDS YP_003078153.1 254793316 8216832 2286385..2287674 1 NC_013008.1 hypothetical protein 2287674 ydiS 8216832 ydiS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078153.1 2286385 D 544404 CDS YP_003078154.1 254793317 8216833 2287671..2287964 1 NC_013008.1 4Fe-4S ferredoxin-type protein 2287964 ydiT 8216833 ydiT Escherichia coli O157:H7 str. TW14359 4Fe-4S ferredoxin-type protein YP_003078154.1 2287671 D 544404 CDS YP_003078155.1 254793318 8216834 2288021..2289562 1 NC_013008.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 2289562 fadK 8216834 fadK Escherichia coli O157:H7 str. TW14359 short chain acyl-CoA synthetase YP_003078155.1 2288021 D 544404 CDS YP_003078156.1 254793319 8216835 complement(2289723..2292101) 1 NC_013008.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 2292101 pps 8216835 pps Escherichia coli O157:H7 str. TW14359 phosphoenolpyruvate synthase YP_003078156.1 2289723 R 544404 CDS YP_003078157.1 254793320 8216836 2292434..2293267 1 NC_013008.1 hypothetical protein 2293267 ydiA 8216836 ydiA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078157.1 2292434 D 544404 CDS YP_003078158.1 254793321 8216837 2293424..2294470 1 NC_013008.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2294470 aroH 8216837 aroH Escherichia coli O157:H7 str. TW14359 phospho-2-dehydro-3-deoxyheptonate aldolase YP_003078158.1 2293424 D 544404 CDS YP_003078159.1 254793322 8216838 2294602..2294793 1 NC_013008.1 hypothetical protein 2294793 ydiE 8216838 ydiE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078159.1 2294602 D 544404 CDS YP_003078160.1 254793323 8216839 complement(2294797..2296233) 1 NC_013008.1 hypothetical protein 2296233 ydiU 8216839 ydiU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078160.1 2294797 R 544404 CDS YP_003078161.1 254793324 8216840 complement(2296296..2297009) 1 NC_013008.1 hypothetical protein 2297009 ydiV 8216840 ydiV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078161.1 2296296 R 544404 CDS YP_003078162.1 254793325 8216841 complement(2297256..2297720) 1 NC_013008.1 lipoprotein 2297720 nlpC 8216841 nlpC Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003078162.1 2297256 R 544404 CDS YP_003078163.1 254793326 8216842 complement(2297798..2298547) 1 NC_013008.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 2298547 btuD 8216842 btuD Escherichia coli O157:H7 str. TW14359 vitamin B12-transporter ATPase YP_003078163.1 2297798 R 544404 CDS YP_003078164.1 254793327 8216843 complement(2298547..2299098) 1 NC_013008.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 2299098 btuE 8216843 btuE Escherichia coli O157:H7 str. TW14359 glutathione peroxidase YP_003078164.1 2298547 R 544404 CDS YP_003078165.1 254793328 8216844 complement(2299161..2300141) 1 NC_013008.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 2300141 btuC 8216844 btuC Escherichia coli O157:H7 str. TW14359 vtamin B12-transporter permease YP_003078165.1 2299161 R 544404 CDS YP_003078166.1 254793329 8216845 complement(2300242..2300541) 1 NC_013008.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 2300541 ihfA 8216845 ihfA Escherichia coli O157:H7 str. TW14359 integration host factor subunit alpha YP_003078166.1 2300242 R 544404 CDS YP_003078167.1 254793330 8216846 complement(2300546..2302933) 1 NC_013008.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2302933 pheT 8216846 pheT Escherichia coli O157:H7 str. TW14359 phenylalanyl-tRNA synthetase subunit beta YP_003078167.1 2300546 R 544404 CDS YP_003078168.1 254793331 8216847 complement(2302948..2303931) 1 NC_013008.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2303931 pheS 8216847 pheS Escherichia coli O157:H7 str. TW14359 phenylalanyl-tRNA synthetase subunit alpha YP_003078168.1 2302948 R 544404 CDS YP_003078170.1 254793333 8216849 complement(2304381..2304737) 1 NC_013008.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2304737 rplT 8216849 rplT Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L20 YP_003078170.1 2304381 R 544404 CDS YP_003078171.1 254793334 8216850 complement(2304790..2304987) 1 NC_013008.1 50S ribosomal protein L35 2304987 rpmI 8216850 rpmI Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L35 YP_003078171.1 2304790 R 544404 CDS YP_003078172.1 254793335 8216851 complement(2305084..2305626) 1 NC_013008.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2305626 infC 8216851 infC Escherichia coli O157:H7 str. TW14359 translation initiation factor IF-3 YP_003078172.1 2305084 R 544404 CDS YP_003078173.1 254793336 8216852 complement(2305630..2307558) 1 NC_013008.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 2307558 thrS 8216852 thrS Escherichia coli O157:H7 str. TW14359 threonyl-tRNA synthetase YP_003078173.1 2305630 R 544404 CDS YP_003078174.1 254793337 8216853 2308081..2309979 1 NC_013008.1 non-LEE-encoded type III effector 2309979 espL1 8216853 espL1 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003078174.1 2308081 D 544404 CDS YP_003078175.1 254793338 8216854 2310154..2310261 1 NC_013008.1 hypothetical protein 2310261 yniD 8216854 yniD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078175.1 2310154 D 544404 CDS YP_003078176.1 254793339 8216855 complement(2310314..2311072) 1 NC_013008.1 hypothetical protein 2311072 ydiY 8216855 ydiY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078176.1 2310314 R 544404 CDS YP_003078177.1 254793340 8216856 2311213..2311320 1 NC_013008.1 hypothetical protein 2311320 8216856 ECSP_2290 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078177.1 2311213 D 544404 CDS YP_003078178.1 254793341 8216857 2311359..2312288 1 NC_013008.1 6-phosphofructokinase 2312288 pfkB 8216857 pfkB Escherichia coli O157:H7 str. TW14359 6-phosphofructokinase YP_003078178.1 2311359 D 544404 CDS YP_003078179.1 254793342 8216858 2312389..2312679 1 NC_013008.1 hypothetical protein 2312679 ydiZ 8216858 ydiZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078179.1 2312389 D 544404 CDS YP_003078180.1 254793343 8216859 2312785..2313645 1 NC_013008.1 phosphotransferase/kinase 2313645 yniA 8216859 yniA Escherichia coli O157:H7 str. TW14359 phosphotransferase/kinase YP_003078180.1 2312785 D 544404 CDS YP_003078181.1 254793344 8216860 complement(2313686..2314222) 1 NC_013008.1 inner membrane protein 2314222 yniB 8216860 yniB Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078181.1 2313686 R 544404 CDS YP_003078182.1 254793345 8216861 2314369..2315037 1 NC_013008.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2315037 yniC 8216861 yniC Escherichia coli O157:H7 str. TW14359 2-deoxyglucose-6-phosphatase YP_003078182.1 2314369 D 544404 CDS YP_003078183.1 254793346 8216862 2315200..2315790 1 NC_013008.1 hypothetical protein 2315790 ydjM 8216862 ydjM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078183.1 2315200 D 544404 CDS YP_003078184.1 254793347 8216863 2315923..2317314 1 NC_013008.1 transporter 2317314 ydjN 8216863 ydjN Escherichia coli O157:H7 str. TW14359 transporter YP_003078184.1 2315923 D 544404 CDS YP_003078185.1 254793348 8216864 complement(2317365..2318132) 1 NC_013008.1 hypothetical protein 2318132 ydjO 8216864 ydjO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078185.1 2317365 R 544404 CDS YP_003078186.1 254793349 8216865 complement(2318409..2318651) 1 NC_013008.1 cell division modulator 2318651 cedA 8216865 cedA Escherichia coli O157:H7 str. TW14359 cell division modulator YP_003078186.1 2318409 R 544404 CDS YP_003078187.1 254793350 8216866 2318855..2321116 1 NC_013008.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2321116 katE 8216866 katE Escherichia coli O157:H7 str. TW14359 hydroperoxidase II YP_003078187.1 2318855 D 544404 CDS YP_003078188.1 254793351 8216867 complement(2321163..2321921) 1 NC_013008.1 hypothetical protein 2321921 chbG 8216867 chbG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078188.1 2321163 R 544404 CDS YP_003078189.1 254793352 8216868 complement(2321934..2323286) 1 NC_013008.1 cryptic phospho-beta-glucosidase, NAD(P)-binding 2323286 chbF 8216868 chbF Escherichia coli O157:H7 str. TW14359 cryptic phospho-beta-glucosidase, NAD(P)-binding YP_003078189.1 2321934 R 544404 CDS YP_003078190.1 254793353 8216869 complement(2323391..2324233) 1 NC_013008.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 2324233 chbR 8216869 chbR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator ChbR YP_003078190.1 2323391 R 544404 CDS YP_003078191.1 254793354 8216870 complement(2324241..2324591) 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2324591 chbA 8216870 chbA Escherichia coli O157:H7 str. TW14359 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_003078191.1 2324241 R 544404 CDS YP_003078192.1 254793355 8216871 complement(2324642..2326000) 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2326000 chbC 8216871 chbC Escherichia coli O157:H7 str. TW14359 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_003078192.1 2324642 R 544404 CDS YP_003078193.1 254793356 8216872 complement(2326085..2326405) 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2326405 chbB 8216872 chbB Escherichia coli O157:H7 str. TW14359 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_003078193.1 2326085 R 544404 CDS YP_003078194.1 254793357 8216873 complement(2326705..2327043) 1 NC_013008.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 2327043 osmE 8216873 osmE Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator OsmE YP_003078194.1 2326705 R 544404 CDS YP_003078195.1 254793358 8216874 2327245..2328072 1 NC_013008.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2328072 nadE 8216874 nadE Escherichia coli O157:H7 str. TW14359 NAD synthetase YP_003078195.1 2327245 D 544404 CDS YP_003078196.1 254793359 8216875 2328302..2329189 1 NC_013008.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2329189 cho 8216875 cho Escherichia coli O157:H7 str. TW14359 nucleotide excision repair endonuclease YP_003078196.1 2328302 D 544404 CDS YP_003078197.1 254793360 8216876 complement(2329149..2329724) 1 NC_013008.1 hypothetical protein 2329724 8216876 ECSP_2310 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078197.1 2329149 R 544404 CDS YP_003078198.1 254793361 8216877 complement(2329927..2330412) 1 NC_013008.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein 2330412 spy 8216877 spy Escherichia coli O157:H7 str. TW14359 periplasmic protein YP_003078198.1 2329927 R 544404 CDS YP_003078199.1 254793362 8216878 complement(2330742..2331710) 1 NC_013008.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 2331710 astE 8216878 astE Escherichia coli O157:H7 str. TW14359 succinylglutamate desuccinylase YP_003078199.1 2330742 R 544404 CDS YP_003078200.1 254793363 8216879 complement(2331703..2333046) 1 NC_013008.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 2333046 astB 8216879 astB Escherichia coli O157:H7 str. TW14359 succinylarginine dihydrolase YP_003078200.1 2331703 R 544404 CDS YP_003078201.1 254793364 8216880 complement(2333043..2334521) 1 NC_013008.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2334521 astD 8216880 astD Escherichia coli O157:H7 str. TW14359 succinylglutamic semialdehyde dehydrogenase YP_003078201.1 2333043 R 544404 CDS YP_003078202.1 254793365 8216881 complement(2334518..2335552) 1 NC_013008.1 arginine succinyltransferase 2335552 astA 8216881 astA Escherichia coli O157:H7 str. TW14359 arginine succinyltransferase YP_003078202.1 2334518 R 544404 CDS YP_003078203.1 254793366 8216882 complement(2335549..2336769) 1 NC_013008.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 2336769 astC 8216882 astC Escherichia coli O157:H7 str. TW14359 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_003078203.1 2335549 R 544404 CDS YP_003078204.1 254793367 8216883 2337215..2338021 1 NC_013008.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2338021 xthA 8216883 xthA Escherichia coli O157:H7 str. TW14359 exonuclease III YP_003078204.1 2337215 D 544404 CDS YP_003078205.1 254793368 8216884 2338188..2338898 1 NC_013008.1 inner membrane protein 2338898 ydjX 8216884 ydjX Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078205.1 2338188 D 544404 CDS YP_003078206.1 254793369 8216885 2338903..2339580 1 NC_013008.1 hypothetical protein 2339580 ydjY 8216885 ydjY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078206.1 2338903 D 544404 CDS YP_003078207.1 254793370 8216886 2339595..2340302 1 NC_013008.1 hypothetical protein 2340302 ydjZ 8216886 ydjZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078207.1 2339595 D 544404 CDS YP_003078208.1 254793371 8216887 2340302..2340850 1 NC_013008.1 hypothetical protein 2340850 ynjA 8216887 ynjA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078208.1 2340302 D 544404 CDS YP_003078209.1 254793372 8216888 2340860..2342026 1 NC_013008.1 ABC transporter solute-binding protein 2342026 ynjB 8216888 ynjB Escherichia coli O157:H7 str. TW14359 ABC transporter solute-binding protein YP_003078209.1 2340860 D 544404 CDS YP_003078210.1 254793373 8216889 2341999..2343534 1 NC_013008.1 fused transporter subunits of ABC superfamily: membrane components 2343534 ynjC 8216889 ynjC Escherichia coli O157:H7 str. TW14359 fused transporter subunits of ABC superfamily: membrane components YP_003078210.1 2341999 D 544404 CDS YP_003078211.1 254793374 8216890 2343534..2344187 1 NC_013008.1 ABC transporter ATP-binding protein 2344187 ynjD 8216890 ynjD Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YP_003078211.1 2343534 D 544404 CDS YP_003078212.1 254793375 8216891 2344254..2345561 1 NC_013008.1 thiosulfate sulfur transferase 2345561 ynjE 8216891 ynjE Escherichia coli O157:H7 str. TW14359 thiosulfate sulfur transferase YP_003078212.1 2344254 D 544404 CDS YP_003078213.1 254793376 8216892 complement(2345570..2346190) 1 NC_013008.1 phosphatidyl transferase, inner membrane protein 2346190 ynjF 8216892 ynjF Escherichia coli O157:H7 str. TW14359 phosphatidyl transferase, inner membrane protein YP_003078213.1 2345570 R 544404 CDS YP_003078214.1 254793377 8216893 2346277..2346684 1 NC_013008.1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2346684 nudG 8216893 nudG Escherichia coli O157:H7 str. TW14359 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_003078214.1 2346277 D 544404 CDS YP_003078215.1 254793378 8216894 complement(2346650..2346922) 1 NC_013008.1 hypothetical protein 2346922 ynjH 8216894 ynjH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078215.1 2346650 R 544404 CDS YP_003078216.1 254793379 8216895 2347158..2348501 1 NC_013008.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2348501 gdhA 8216895 gdhA Escherichia coli O157:H7 str. TW14359 glutamate dehydrogenase YP_003078216.1 2347158 D 544404 CDS YP_003078217.1 254793380 8216896 complement(2348618..2349658) 1 NC_013008.1 hypothetical protein 2349658 ynjI 8216896 ynjI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078217.1 2348618 R 544404 CDS YP_003078218.1 254793381 8216897 complement(2349786..2351747) 1 NC_013008.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2351747 topB 8216897 topB Escherichia coli O157:H7 str. TW14359 DNA topoisomerase III YP_003078218.1 2349786 R 544404 CDS YP_003078219.1 254793382 8216898 complement(2351752..2352795) 1 NC_013008.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2352795 selD 8216898 selD Escherichia coli O157:H7 str. TW14359 selenophosphate synthetase YP_003078219.1 2351752 R 544404 CDS YP_003078220.1 254793383 8216899 complement(2352912..2353463) 1 NC_013008.1 hypothetical protein 2353463 ydjA 8216899 ydjA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078220.1 2352912 R 544404 CDS YP_003078221.1 254793384 8216900 2353624..2355480 1 NC_013008.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2355480 sppA 8216900 sppA Escherichia coli O157:H7 str. TW14359 protease 4 YP_003078221.1 2353624 D 544404 CDS YP_003078222.1 254793385 8216901 2355596..2356306 1 NC_013008.1 hypothetical protein 2356306 8216901 ECSP_2335 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078222.1 2355596 D 544404 CDS YP_003078223.1 254793386 8216902 2356438..2357454 1 NC_013008.1 converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2357454 ansA 8216902 ansA Escherichia coli O157:H7 str. TW14359 cytoplasmic asparaginase I YP_003078223.1 2356438 D 544404 CDS YP_003078224.1 254793387 8216903 2357465..2358106 1 NC_013008.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2358106 pncA 8216903 pncA Escherichia coli O157:H7 str. TW14359 nicotinamidase/pyrazinamidase YP_003078224.1 2357465 D 544404 CDS YP_003078225.1 254793388 8216904 complement(2358199..2359449) 1 NC_013008.1 transporter 2359449 ydjE 8216904 ydjE Escherichia coli O157:H7 str. TW14359 transporter YP_003078225.1 2358199 R 544404 CDS YP_003078226.1 254793389 8216905 2359512..2359838 1 NC_013008.1 transposase, IS629 2359838 8216905 ECSP_2339 Escherichia coli O157:H7 str. TW14359 transposase, IS629 YP_003078226.1 2359512 D 544404 CDS YP_003078227.1 254793390 8216906 2359838..2360725 1 NC_013008.1 transposase, IS629 2360725 8216906 ECSP_2340 Escherichia coli O157:H7 str. TW14359 transposase, IS629 YP_003078227.1 2359838 D 544404 CDS YP_003078228.1 254793391 8216907 2360843..2360986 1 NC_013008.1 hypothetical protein 2360986 8216907 ECSP_2341 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078228.1 2360843 D 544404 CDS YP_003078229.1 254793392 8216908 complement(2360988..2361746) 1 NC_013008.1 DNA-binding transcriptional regulator 2361746 ydjF 8216908 ydjF Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078229.1 2360988 R 544404 CDS YP_003078230.1 254793393 8216909 complement(2361883..2362863) 1 NC_013008.1 oxidoreductase 2362863 ydjG 8216909 ydjG Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078230.1 2361883 R 544404 CDS YP_003078231.1 254793394 8216910 complement(2362873..2363805) 1 NC_013008.1 kinase 2363805 ydjH 8216910 ydjH Escherichia coli O157:H7 str. TW14359 kinase YP_003078231.1 2362873 R 544404 CDS YP_003078232.1 254793395 8216911 complement(2363810..2364646) 1 NC_013008.1 aldolase 2364646 ydjI 8216911 ydjI Escherichia coli O157:H7 str. TW14359 aldolase YP_003078232.1 2363810 R 544404 CDS YP_003078233.1 254793396 8216912 complement(2364667..2365710) 1 NC_013008.1 oxidoreductase 2365710 ydjJ 8216912 ydjJ Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078233.1 2364667 R 544404 CDS YP_003078234.1 254793397 8216913 complement(2365727..2367106) 1 NC_013008.1 transporter 2367106 ydjK 8216913 ydjK Escherichia coli O157:H7 str. TW14359 transporter YP_003078234.1 2365727 R 544404 CDS YP_003078235.1 254793398 8216914 complement(2367133..2368209) 1 NC_013008.1 oxidoreductase 2368209 ydjL 8216914 ydjL Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078235.1 2367133 R 544404 CDS YP_003078236.1 254793399 8216915 complement(2368579..2368851) 1 NC_013008.1 hypothetical protein 2368851 yeaC 8216915 yeaC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078236.1 2368579 R 544404 CDS YP_003078237.1 254793400 8216916 complement(2368893..2369306) 1 NC_013008.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2369306 yeaA 8216916 yeaA Escherichia coli O157:H7 str. TW14359 methionine sulfoxide reductase B YP_003078237.1 2368893 R 544404 CDS YP_003078238.1 254793401 8216917 2369648..2370643 1 NC_013008.1 glyceraldehyde-3-phosphate dehydrogenase A 2370643 gapA 8216917 gapA Escherichia coli O157:H7 str. TW14359 glyceraldehyde-3-phosphate dehydrogenase A YP_003078238.1 2369648 D 544404 CDS YP_003078239.1 254793402 8216918 2370727..2371611 1 NC_013008.1 hypothetical protein 2371611 yeaD 8216918 yeaD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078239.1 2370727 D 544404 CDS YP_003078240.1 254793403 8216919 complement(2371662..2372516) 1 NC_013008.1 oxidoreductase 2372516 yeaE 8216919 yeaE Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078240.1 2371662 R 544404 CDS YP_003078241.1 254793404 8216920 complement(2372606..2373352) 1 NC_013008.1 scaffolding protein for murein synthesizing machinery 2373352 mipA 8216920 mipA Escherichia coli O157:H7 str. TW14359 scaffolding protein for murein synthesizing machinery YP_003078241.1 2372606 R 544404 CDS YP_003078242.1 254793405 8216921 2373788..2375722 1 NC_013008.1 hypothetical protein 2375722 yeaG 8216921 yeaG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078242.1 2373788 D 544404 CDS YP_003078243.1 254793406 8216922 2375835..2377118 1 NC_013008.1 hypothetical protein 2377118 yeaH 8216922 yeaH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078243.1 2375835 D 544404 CDS YP_003078244.1 254793407 8216923 2377406..2378740 1 NC_013008.1 diguanylate cyclase 2378740 yeaI 8216923 yeaI Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003078244.1 2377406 D 544404 CDS YP_003078245.1 254793408 8216924 2378921..2380411 1 NC_013008.1 diguanylate cyclase 2380411 yeaJ 8216924 yeaJ Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003078245.1 2378921 D 544404 CDS YP_003078246.1 254793409 8216925 2380454..2380957 1 NC_013008.1 hypothetical protein 2380957 yeaK 8216925 yeaK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078246.1 2380454 D 544404 CDS YP_003078247.1 254793410 8216926 complement(2380958..2381062) 1 NC_013008.1 hypothetical protein 2381062 yoaI 8216926 yoaI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078247.1 2380958 R 544404 CDS YP_003078248.1 254793411 8216927 2381232..2381678 1 NC_013008.1 hypothetical protein 2381678 yeaL 8216927 yeaL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078248.1 2381232 D 544404 CDS YP_003078249.1 254793412 8216928 complement(2381635..2382456) 1 NC_013008.1 DNA-binding transcriptional regulator 2382456 yeaM 8216928 yeaM Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078249.1 2381635 R 544404 CDS YP_003078250.1 254793413 8216929 2382553..2383734 1 NC_013008.1 transporter 2383734 yeaN 8216929 yeaN Escherichia coli O157:H7 str. TW14359 transporter YP_003078250.1 2382553 D 544404 CDS YP_003078251.1 254793414 8216930 2383789..2384136 1 NC_013008.1 hypothetical protein 2384136 yeaO 8216930 yeaO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078251.1 2383789 D 544404 CDS YP_003078252.1 254793415 8216931 complement(2384158..2384412) 1 NC_013008.1 outer membrane protein 2384412 yoaF 8216931 yoaF Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003078252.1 2384158 R 544404 CDS YP_003078253.1 254793416 8216932 2384595..2385620 1 NC_013008.1 diguanylate cyclase 2385620 yeaP 8216932 yeaP Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003078253.1 2384595 D 544404 CDS YP_003078254.1 254793417 8216933 complement(2385887..2386135) 1 NC_013008.1 hypothetical protein 2386135 yeaQ 8216933 yeaQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078254.1 2385887 R 544404 CDS YP_003078255.1 254793418 8216934 complement(2386282..2386464) 1 NC_013008.1 hypothetical protein 2386464 yoaG 8216934 yoaG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078255.1 2386282 R 544404 CDS YP_003078256.1 254793419 8216935 complement(2386468..2386827) 1 NC_013008.1 hypothetical protein 2386827 yeaR 8216935 yeaR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078256.1 2386468 R 544404 CDS YP_003078257.1 254793420 8216936 complement(2387000..2387638) 1 NC_013008.1 leucine export protein LeuE 2387638 yeaS 8216936 yeaS Escherichia coli O157:H7 str. TW14359 leucine export protein LeuE YP_003078257.1 2387000 R 544404 CDS YP_003078258.1 254793421 8216937 complement(2387765..2388688) 1 NC_013008.1 DNA-binding transcriptional regulator 2388688 yeaT 8216937 yeaT Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078258.1 2387765 R 544404 CDS YP_003078259.1 254793422 8216938 2388791..2389876 1 NC_013008.1 dehydrogenase 2389876 yeaU 8216938 yeaU Escherichia coli O157:H7 str. TW14359 dehydrogenase YP_003078259.1 2388791 D 544404 CDS YP_003078260.1 254793423 8216939 2390127..2391737 1 NC_013008.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2391737 yeaV 8216939 yeaV Escherichia coli O157:H7 str. TW14359 transporter YP_003078260.1 2390127 D 544404 CDS YP_003078261.1 254793424 8216940 2391769..2392893 1 NC_013008.1 2Fe-2S cluster-containing protein 2392893 yeaW 8216940 yeaW Escherichia coli O157:H7 str. TW14359 2Fe-2S cluster-containing protein YP_003078261.1 2391769 D 544404 CDS YP_003078262.1 254793425 8216941 2392949..2393914 1 NC_013008.1 oxidoreductase 2393914 yeaX 8216941 yeaX Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078262.1 2392949 D 544404 CDS YP_003078263.1 254793426 8216942 complement(2393968..2395095) 1 NC_013008.1 ribonuclease D 2395095 rnd 8216942 rnd Escherichia coli O157:H7 str. TW14359 ribonuclease D YP_003078263.1 2393968 R 544404 CDS YP_003078264.1 254793427 8216943 complement(2395165..2396850) 1 NC_013008.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2396850 fadD 8216943 fadD Escherichia coli O157:H7 str. TW14359 long-chain-fatty-acid--CoA ligase YP_003078264.1 2395165 R 544404 CDS YP_003078265.1 254793428 8216944 complement(2397055..2397636) 1 NC_013008.1 lipoprotein 2397636 yeaY 8216944 yeaY Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003078265.1 2397055 R 544404 CDS YP_003078266.1 254793429 8216945 complement(2397676..2398371) 1 NC_013008.1 peptidase 2398371 yeaZ 8216945 yeaZ Escherichia coli O157:H7 str. TW14359 peptidase YP_003078266.1 2397676 R 544404 CDS YP_003078267.1 254793430 8216946 complement(2398429..2400339) 1 NC_013008.1 hypothetical protein 2400339 yoaA 8216946 yoaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078267.1 2398429 R 544404 CDS YP_003078268.1 254793431 8216947 2400471..2400815 1 NC_013008.1 hypothetical protein 2400815 yoaB 8216947 yoaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078268.1 2400471 D 544404 CDS YP_003078269.1 254793432 8216948 complement(2400849..2400980) 1 NC_013008.1 hypothetical protein 2400980 8216948 ECSP_2382 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078269.1 2400849 R 544404 CDS YP_003078270.1 254793433 8216949 2401237..2401536 1 NC_013008.1 hypothetical protein 2401536 yoaC 8216949 yoaC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078270.1 2401237 D 544404 CDS YP_003078271.1 254793434 8216950 complement(2401656..2401835) 1 NC_013008.1 hypothetical protein 2401835 yoaH 8216950 yoaH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078271.1 2401656 R 544404 CDS YP_003078272.1 254793435 8216951 2401909..2403270 1 NC_013008.1 aminodeoxychorismate synthase subunit I 2403270 pabB 8216951 pabB Escherichia coli O157:H7 str. TW14359 aminodeoxychorismate synthase subunit I YP_003078272.1 2401909 D 544404 CDS YP_003078273.1 254793436 8216952 2403274..2403852 1 NC_013008.1 hypothetical protein 2403852 yeaB 8216952 yeaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078273.1 2403274 D 544404 CDS YP_003078274.1 254793437 8216953 2404036..2405400 1 NC_013008.1 L-serine deaminase I 2405400 sdaA 8216953 sdaA Escherichia coli O157:H7 str. TW14359 L-serine deaminase I YP_003078274.1 2404036 D 544404 CDS YP_003078275.1 254793438 8216954 2405531..2407129 1 NC_013008.1 phosphodiesterase 2407129 yoaD 8216954 yoaD Escherichia coli O157:H7 str. TW14359 phosphodiesterase YP_003078275.1 2405531 D 544404 CDS YP_003078276.1 254793439 8216955 complement(2407133..2408689) 1 NC_013008.1 fused membrane protein, conserved protein 2408689 yoaE 8216955 yoaE Escherichia coli O157:H7 str. TW14359 fused membrane protein, conserved protein YP_003078276.1 2407133 R 544404 CDS YP_003078277.1 254793440 8216956 2409152..2410123 1 NC_013008.1 mannose-specific PTS enzyme 2410123 manX 8216956 manX Escherichia coli O157:H7 str. TW14359 mannose-specific PTS enzyme YP_003078277.1 2409152 D 544404 CDS YP_003078278.1 254793441 8216957 2410186..2410986 1 NC_013008.1 PTS system mannose-specific protein subunit IIC 2410986 manY 8216957 manY Escherichia coli O157:H7 str. TW14359 PTS system mannose-specific protein subunit IIC YP_003078278.1 2410186 D 544404 CDS YP_003078279.1 254793442 8216958 2410990..2411850 1 NC_013008.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2411850 manZ 8216958 manZ Escherichia coli O157:H7 str. TW14359 PTS system mannose-specific transporter subunit IID YP_003078279.1 2410990 D 544404 CDS YP_003078280.1 254793443 8216959 2411905..2412363 1 NC_013008.1 hypothetical protein 2412363 yobD 8216959 yobD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078280.1 2411905 D 544404 CDS YP_003078281.1 254793444 8216960 2412793..2413359 1 NC_013008.1 membrane protein YebN; hypothetical protein 2413359 yebN 8216960 yebN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078281.1 2412793 D 544404 CDS YP_003078282.1 254793445 8216961 complement(2413356..2414165) 1 NC_013008.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase 2414165 rrmA 8216961 rrmA Escherichia coli O157:H7 str. TW14359 23S rRNA methyltransferase YP_003078282.1 2413356 R 544404 CDS YP_003078283.1 254793446 8216962 complement(2414331..2414540) 1 NC_013008.1 cold shock-like protein CspC 2414540 cspC 8216962 cspC Escherichia coli O157:H7 str. TW14359 cold shock-like protein CspC YP_003078283.1 2414331 R 544404 CDS YP_003078284.1 254793447 8216963 complement(2414553..2414696) 1 NC_013008.1 hypothetical protein 2414696 yobF 8216963 yobF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078284.1 2414553 R 544404 CDS YP_003078285.1 254793448 8216964 complement(2415365..2415652) 1 NC_013008.1 hypothetical protein 2415652 yebO 8216964 yebO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078285.1 2415365 R 544404 CDS YP_003078286.1 254793449 8216965 complement(2415727..2415870) 1 NC_013008.1 hypothetical protein 2415870 yobG 8216965 yobG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078286.1 2415727 R 544404 CDS YP_003078287.1 254793450 8216966 2416030..2416269 1 NC_013008.1 hypothetical protein 2416269 yobH 8216966 yobH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078287.1 2416030 D 544404 CDS YP_003078288.1 254793451 8216967 complement(2416413..2417204) 1 NC_013008.1 DNA-binding transcriptional regulatory protein KdgR 2417204 kdgR 8216967 kdgR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulatory protein KdgR YP_003078288.1 2416413 R 544404 CDS YP_003078289.1 254793452 8216968 2417381..2418754 1 NC_013008.1 transporter 2418754 yebQ 8216968 yebQ Escherichia coli O157:H7 str. TW14359 transporter YP_003078289.1 2417381 D 544404 CDS YP_003078290.1 254793453 8216969 complement(2418800..2419681) 1 NC_013008.1 metalloprotease; heat shock protein HtpX 2419681 htpX 8216969 htpX Escherichia coli O157:H7 str. TW14359 heat shock protein HtpX YP_003078290.1 2418800 R 544404 CDS YP_003078291.1 254793454 8216970 complement(2419873..2421921) 1 NC_013008.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2421921 prc 8216970 prc Escherichia coli O157:H7 str. TW14359 carboxy-terminal protease YP_003078291.1 2419873 R 544404 CDS YP_003078292.1 254793455 8216971 complement(2421941..2422639) 1 NC_013008.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 2422639 proQ 8216971 proQ Escherichia coli O157:H7 str. TW14359 solute/DNA competence effector YP_003078292.1 2421941 R 544404 CDS YP_003078293.1 254793456 8216972 complement(2422736..2423233) 1 NC_013008.1 hypothetical protein 2423233 yebR 8216972 yebR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078293.1 2422736 R 544404 CDS YP_003078294.1 254793457 8216973 2423363..2424646 1 NC_013008.1 hypothetical protein 2424646 yebS 8216973 yebS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078294.1 2423363 D 544404 CDS YP_003078295.1 254793458 8216974 2424615..2427248 1 NC_013008.1 hypothetical protein 2427248 yebT 8216974 yebT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078295.1 2424615 D 544404 CDS YP_003078296.1 254793459 8216975 2427329..2428768 1 NC_013008.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2428768 yebU 8216975 yebU Escherichia coli O157:H7 str. TW14359 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_003078296.1 2427329 D 544404 CDS YP_003078297.1 254793460 8216976 2428886..2429122 1 NC_013008.1 hypothetical protein 2429122 yebV 8216976 yebV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078297.1 2428886 D 544404 CDS YP_003078298.1 254793461 8216977 2429227..2429418 1 NC_013008.1 hypothetical protein 2429418 yebW 8216977 yebW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078298.1 2429227 D 544404 CDS YP_003078299.1 254793462 8216978 complement(2429419..2430075) 1 NC_013008.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 2430075 pphA 8216978 pphA Escherichia coli O157:H7 str. TW14359 serine/threonine protein phosphatase 1 YP_003078299.1 2429419 R 544404 CDS YP_003078300.1 254793463 8216979 complement(2430471..2430812) 1 NC_013008.1 hypothetical protein 2430812 yebY 8216979 yebY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078300.1 2430471 R 544404 CDS YP_003078301.1 254793464 8216980 complement(2430825..2431697) 1 NC_013008.1 inner membrane protein 2431697 yebZ 8216980 yebZ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078301.1 2430825 R 544404 CDS YP_003078302.1 254793465 8216981 complement(2431701..2432075) 1 NC_013008.1 hypothetical protein 2432075 yobA 8216981 yobA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078302.1 2431701 R 544404 CDS YP_003078303.1 254793466 8216982 2432214..2432444 1 NC_013008.1 DNA polymerase III subunit theta 2432444 holE 8216982 holE Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit theta YP_003078303.1 2432214 D 544404 CDS YP_003078304.1 254793467 8216983 2432546..2433202 1 NC_013008.1 hypothetical protein 2433202 yobB 8216983 yobB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078304.1 2432546 D 544404 CDS YP_003078305.1 254793468 8216984 2433226..2433888 1 NC_013008.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2433888 exoX 8216984 exoX Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease X YP_003078305.1 2433226 D 544404 CDS YP_003078306.1 254793469 8216985 complement(2433885..2435945) 1 NC_013008.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 2435945 ptrB 8216985 ptrB Escherichia coli O157:H7 str. TW14359 protease 2 YP_003078306.1 2433885 R 544404 CDS YP_003078307.1 254793470 8216986 complement(2436154..2436813) 1 NC_013008.1 hypothetical protein 2436813 yebE 8216986 yebE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078307.1 2436154 R 544404 CDS YP_003078308.1 254793471 8216987 complement(2437140..2437496) 1 NC_013008.1 hypothetical protein; unknown function; hypothetical protein 2437496 yebF 8216987 yebF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078308.1 2437140 R 544404 CDS YP_003078309.1 254793472 8216988 complement(2437563..2437853) 1 NC_013008.1 DNA damage-inducible protein YebG 2437853 yebG 8216988 yebG Escherichia coli O157:H7 str. TW14359 DNA damage-inducible protein YebG YP_003078309.1 2437563 R 544404 CDS YP_003078310.1 254793473 8216989 2437987..2439165 1 NC_013008.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2439165 purT 8216989 purT Escherichia coli O157:H7 str. TW14359 phosphoribosylglycinamide formyltransferase 2 YP_003078310.1 2437987 D 544404 CDS YP_003078311.1 254793474 8216990 complement(2439221..2439862) 1 NC_013008.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2439862 eda 8216990 eda Escherichia coli O157:H7 str. TW14359 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_003078311.1 2439221 R 544404 CDS YP_003078312.1 254793475 8216991 complement(2439899..2441710) 1 NC_013008.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2441710 edd 8216991 edd Escherichia coli O157:H7 str. TW14359 phosphogluconate dehydratase YP_003078312.1 2439899 R 544404 CDS YP_003078313.1 254793476 8216992 complement(2441945..2443420) 1 NC_013008.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2443420 zwf 8216992 zwf Escherichia coli O157:H7 str. TW14359 glucose-6-phosphate 1-dehydrogenase YP_003078313.1 2441945 R 544404 CDS YP_003078314.1 254793477 8216993 2443758..2444627 1 NC_013008.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2444627 yebK 8216993 yebK Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator HexR YP_003078314.1 2443758 D 544404 CDS YP_003078315.1 254793478 8216994 2444755..2446197 1 NC_013008.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2446197 pykA 8216994 pykA Escherichia coli O157:H7 str. TW14359 pyruvate kinase YP_003078315.1 2444755 D 544404 CDS YP_003078316.1 254793479 8216995 complement(2446328..2447299) 1 NC_013008.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2447299 lpxM 8216995 lpxM Escherichia coli O157:H7 str. TW14359 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_003078316.1 2446328 R 544404 CDS YP_003078317.1 254793480 8216996 complement(2447419..2448741) 1 NC_013008.1 hypothetical protein 2448741 yebA 8216996 yebA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078317.1 2447419 R 544404 CDS YP_003078318.1 254793481 8216997 complement(2448757..2449689) 1 NC_013008.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 2449689 znuA 8216997 znuA Escherichia coli O157:H7 str. TW14359 high-affinity zinc transporter periplasmic component YP_003078318.1 2448757 R 544404 CDS YP_003078319.1 254793482 8216998 2449768..2450523 1 NC_013008.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2450523 znuC 8216998 znuC Escherichia coli O157:H7 str. TW14359 high-affinity zinc transporter ATPase YP_003078319.1 2449768 D 544404 CDS YP_003078320.1 254793483 8216999 2450520..2451305 1 NC_013008.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 2451305 znuB 8216999 znuB Escherichia coli O157:H7 str. TW14359 high-affinity zinc transporter membrane component YP_003078320.1 2450520 D 544404 CDS YP_003078321.1 254793484 8217000 complement(2451551..2452561) 1 NC_013008.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2452561 ruvB 8217000 ruvB Escherichia coli O157:H7 str. TW14359 Holliday junction DNA helicase RuvB YP_003078321.1 2451551 R 544404 CDS YP_003078322.1 254793485 8217001 complement(2452570..2453181) 1 NC_013008.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2453181 ruvA 8217001 ruvA Escherichia coli O157:H7 str. TW14359 Holliday junction DNA helicase RuvA YP_003078322.1 2452570 R 544404 CDS YP_003078323.1 254793486 8217002 2453456..2454058 1 NC_013008.1 hypothetical protein 2454058 yebB 8217002 yebB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078323.1 2453456 D 544404 CDS YP_003078324.1 254793487 8217003 complement(2454060..2454581) 1 NC_013008.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2454581 ruvC 8217003 ruvC Escherichia coli O157:H7 str. TW14359 Holliday junction resolvase YP_003078324.1 2454060 R 544404 CDS YP_003078325.1 254793488 8217004 complement(2454616..2455356) 1 NC_013008.1 hypothetical protein 2455356 yebC 8217004 yebC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078325.1 2454616 R 544404 CDS YP_003078326.1 254793489 8217005 complement(2455385..2455837) 1 NC_013008.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2455837 ntpA 8217005 ntpA Escherichia coli O157:H7 str. TW14359 dATP pyrophosphohydrolase YP_003078326.1 2455385 R 544404 CDS YP_003078327.1 254793490 8217006 complement(2455955..2457727) 1 NC_013008.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2457727 aspS 8217006 aspS Escherichia coli O157:H7 str. TW14359 aspartyl-tRNA synthetase YP_003078327.1 2455955 R 544404 CDS YP_003078328.1 254793491 8217007 2458037..2458603 1 NC_013008.1 hypothetical protein 2458603 yecD 8217007 yecD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078328.1 2458037 D 544404 CDS YP_003078329.1 254793492 8217008 2458600..2459418 1 NC_013008.1 hypothetical protein 2459418 yecE 8217008 yecE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078329.1 2458600 D 544404 CDS YP_003078330.1 254793493 8217009 2459471..2459866 1 NC_013008.1 inner membrane protein 2459866 yecN 8217009 yecN Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078330.1 2459471 D 544404 CDS YP_003078331.1 254793494 8217010 2459907..2460650 1 NC_013008.1 tRNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase 2460650 cmoA 8217010 cmoA Escherichia coli O157:H7 str. TW14359 tRNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase YP_003078331.1 2459907 D 544404 CDS YP_003078332.1 254793495 8217011 2460647..2461618 1 NC_013008.1 tRNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase 2461618 cmoB 8217011 cmoB Escherichia coli O157:H7 str. TW14359 tRNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase YP_003078332.1 2460647 D 544404 CDS YP_003078333.1 254793496 8217012 complement(2461783..2464212) 1 NC_013008.1 trimethylamine N-oxide reductase system III, catalytic subunit 2464212 torZ 8217012 torZ Escherichia coli O157:H7 str. TW14359 trimethylamine N-oxide reductase system III, catalytic subunit YP_003078333.1 2461783 R 544404 CDS YP_003078334.1 254793497 8217013 complement(2464237..2465337) 1 NC_013008.1 TMAO reductase III (TorYZ), cytochrome c-type subunit 2465337 torY 8217013 torY Escherichia coli O157:H7 str. TW14359 TMAO reductase III (TorYZ), cytochrome c-type subunit YP_003078334.1 2464237 R 544404 CDS YP_003078335.1 254793498 8217014 complement(2465725..2466471) 1 NC_013008.1 copper homeostasis protein CutC 2466471 cutC 8217014 cutC Escherichia coli O157:H7 str. TW14359 copper homeostasis protein CutC YP_003078335.1 2465725 R 544404 CDS YP_003078336.1 254793499 8217015 complement(2466485..2467051) 1 NC_013008.1 hypothetical protein 2467051 yecM 8217015 yecM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078336.1 2466485 R 544404 CDS YP_003078337.1 254793500 8217016 2467267..2469000 1 NC_013008.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2469000 argS 8217016 argS Escherichia coli O157:H7 str. TW14359 arginyl-tRNA synthetase YP_003078337.1 2467267 D 544404 CDS YP_003078338.1 254793501 8217017 2469177..2469665 1 NC_013008.1 hypothetical protein 2469665 yecT 8217017 yecT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078338.1 2469177 D 544404 CDS YP_003078339.1 254793502 8217018 complement(2469785..2470177) 1 NC_013008.1 hypothetical protein 2470177 flhE 8217018 flhE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078339.1 2469785 R 544404 CDS YP_003078340.1 254793503 8217019 complement(2470177..2472255) 1 NC_013008.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2472255 flhA 8217019 flhA Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FlhA YP_003078340.1 2470177 R 544404 CDS YP_003078341.1 254793504 8217020 complement(2472248..2473396) 1 NC_013008.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2473396 flhB 8217020 flhB Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FlhB YP_003078341.1 2472248 R 544404 CDS YP_003078342.1 254793505 8217021 complement(2473598..2474242) 1 NC_013008.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 2474242 cheZ 8217021 cheZ Escherichia coli O157:H7 str. TW14359 chemotaxis regulator CheZ YP_003078342.1 2473598 R 544404 CDS YP_003078343.1 254793506 8217022 complement(2474253..2474642) 1 NC_013008.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 2474642 cheY 8217022 cheY Escherichia coli O157:H7 str. TW14359 chemotaxis regulatory protein CheY YP_003078343.1 2474253 R 544404 CDS YP_003078344.1 254793507 8217023 complement(2474657..2475706) 1 NC_013008.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2475706 cheB 8217023 cheB Escherichia coli O157:H7 str. TW14359 chemotaxis-specific methylesterase YP_003078344.1 2474657 R 544404 CDS YP_003078345.1 254793508 8217024 complement(2475709..2476569) 1 NC_013008.1 methylates the MCP; chemotaxis methyltransferase CheR 2476569 cheR 8217024 cheR Escherichia coli O157:H7 str. TW14359 chemotaxis methyltransferase CheR YP_003078345.1 2475709 R 544404 CDS YP_003078346.1 254793509 8217025 complement(2476588..2478189) 1 NC_013008.1 mediates taxis toward dipeptides; methyl-accepting protein IV 2478189 tap 8217025 tap Escherichia coli O157:H7 str. TW14359 methyl-accepting protein IV YP_003078346.1 2476588 R 544404 CDS YP_003078347.1 254793510 8217026 complement(2478235..2479896) 1 NC_013008.1 methyl-accepting chemotaxis protein II 2479896 tar 8217026 tar Escherichia coli O157:H7 str. TW14359 methyl-accepting chemotaxis protein II YP_003078347.1 2478235 R 544404 CDS YP_003078348.1 254793511 8217027 complement(2480039..2480542) 1 NC_013008.1 purine-binding chemotaxis protein 2480542 cheW 8217027 cheW Escherichia coli O157:H7 str. TW14359 purine-binding chemotaxis protein YP_003078348.1 2480039 R 544404 CDS YP_003078349.1 254793512 8217028 complement(2480563..2482527) 1 NC_013008.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 2482527 cheA 8217028 cheA Escherichia coli O157:H7 str. TW14359 chemotaxis protein CheA YP_003078349.1 2480563 R 544404 CDS YP_003078350.1 254793513 8217029 complement(2482532..2483458) 1 NC_013008.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2483458 motB 8217029 motB Escherichia coli O157:H7 str. TW14359 flagellar motor protein MotB YP_003078350.1 2482532 R 544404 CDS YP_003078351.1 254793514 8217030 complement(2483455..2484342) 1 NC_013008.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2484342 motA 8217030 motA Escherichia coli O157:H7 str. TW14359 flagellar motor protein MotA YP_003078351.1 2483455 R 544404 CDS YP_003078352.1 254793515 8217031 complement(2484469..2485047) 1 NC_013008.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 2485047 flhC 8217031 flhC Escherichia coli O157:H7 str. TW14359 transcriptional activator FlhC YP_003078352.1 2484469 R 544404 CDS YP_003078353.1 254793516 8217032 complement(2485050..2485400) 1 NC_013008.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2485400 flhD 8217032 flhD Escherichia coli O157:H7 str. TW14359 transcriptional activator FlhD YP_003078353.1 2485050 R 544404 CDS YP_003078355.1 254793518 8217034 2486180..2486608 1 NC_013008.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2486608 yecG 8217034 yecG Escherichia coli O157:H7 str. TW14359 universal stress protein UspC YP_003078355.1 2486180 D 544404 CDS YP_003078356.1 254793519 8217035 complement(2486615..2488039) 1 NC_013008.1 trehalose-6-phosphate synthase 2488039 otsA 8217035 otsA Escherichia coli O157:H7 str. TW14359 trehalose-6-phosphate synthase YP_003078356.1 2486615 R 544404 CDS YP_003078357.1 254793520 8217036 complement(2488014..2488814) 1 NC_013008.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2488814 otsB 8217036 otsB Escherichia coli O157:H7 str. TW14359 trehalose-6-phosphate phosphatase YP_003078357.1 2488014 R 544404 CDS YP_003078358.1 254793521 8217037 complement(2488981..2489970) 1 NC_013008.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2489970 araH 8217037 araH Escherichia coli O157:H7 str. TW14359 L-arabinose transporter permease YP_003078358.1 2488981 R 544404 CDS YP_003078359.1 254793522 8217038 complement(2489982..2491496) 1 NC_013008.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2491496 araG 8217038 araG Escherichia coli O157:H7 str. TW14359 L-arabinose transporter ATP-binding protein YP_003078359.1 2489982 R 544404 CDS YP_003078360.1 254793523 8217039 complement(2491566..2492555) 1 NC_013008.1 L-arabinose-binding periplasmic protein 2492555 araF 8217039 araF Escherichia coli O157:H7 str. TW14359 L-arabinose-binding periplasmic protein YP_003078360.1 2491566 R 544404 CDS YP_003078361.1 254793524 8217040 2493352..2493855 1 NC_013008.1 ferritin-like protein 2493855 yecI 8217040 yecI Escherichia coli O157:H7 str. TW14359 ferritin-like protein YP_003078361.1 2493352 D 544404 CDS YP_003078362.1 254793525 8217041 complement(2493935..2494186) 1 NC_013008.1 hypothetical protein 2494186 yecJ 8217041 yecJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078362.1 2493935 R 544404 CDS YP_003078363.1 254793526 8217042 2494298..2494444 1 NC_013008.1 hypothetical protein 2494444 8217042 ECSP_2476 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078363.1 2494298 D 544404 CDS YP_003078364.1 254793527 8217043 2494649..2494972 1 NC_013008.1 hypothetical protein 2494972 yecR 8217043 yecR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078364.1 2494649 D 544404 CDS YP_003078365.1 254793528 8217044 2495143..2495640 1 NC_013008.1 cytoplasmic iron storage protein; ferritin 2495640 ftn 8217044 ftn Escherichia coli O157:H7 str. TW14359 ferritin YP_003078365.1 2495143 D 544404 CDS YP_003078366.1 254793529 8217045 complement(2495677..2495916) 1 NC_013008.1 hypothetical protein 2495916 yecH 8217045 yecH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078366.1 2495677 R 544404 CDS YP_003078367.1 254793530 8217046 2496108..2497319 1 NC_013008.1 tyrosine transporter 2497319 tyrP 8217046 tyrP Escherichia coli O157:H7 str. TW14359 tyrosine transporter YP_003078367.1 2496108 D 544404 CDS YP_003078368.1 254793531 8217047 complement(2497381..2498046) 1 NC_013008.1 hypothetical protein 2498046 yecA 8217047 yecA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078368.1 2497381 R 544404 CDS YP_003078369.1 254793532 8217048 complement(2498403..2499404) 1 NC_013008.1 integrase for prophage CP-933T 2499404 intT 8217048 intT Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933T YP_003078369.1 2498403 R 544404 CDS YP_003078370.1 254793533 8217049 complement(2499410..2499757) 1 NC_013008.1 hypothetical protein 2499757 8217049 ECSP_2483 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078370.1 2499410 R 544404 CDS YP_003078371.1 254793534 8217050 complement(2499787..2500437) 1 NC_013008.1 hypothetical protein 2500437 8217050 ECSP_2484 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078371.1 2499787 R 544404 CDS YP_003078372.1 254793535 8217051 complement(2500453..2500857) 1 NC_013008.1 hypothetical protein 2500857 8217051 ECSP_2485 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078372.1 2500453 R 544404 CDS YP_003078373.1 254793536 8217052 2501156..2501359 1 NC_013008.1 prophage regulator CP-933T 2501359 coxT 8217052 coxT Escherichia coli O157:H7 str. TW14359 prophage regulator CP-933T YP_003078373.1 2501156 D 544404 CDS YP_003078374.1 254793537 8217053 2501381..2501731 1 NC_013008.1 hypothetical protein 2501731 8217053 ECSP_2487 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078374.1 2501381 D 544404 CDS YP_003078375.1 254793538 8217054 2501742..2502020 1 NC_013008.1 hypothetical protein 2502020 8217054 ECSP_2488 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078375.1 2501742 D 544404 CDS YP_003078376.1 254793539 8217055 2502032..2502274 1 NC_013008.1 hypothetical protein 2502274 8217055 ECSP_2489 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078376.1 2502032 D 544404 CDS YP_003078377.1 254793540 8217056 2502477..2502893 1 NC_013008.1 hypothetical protein 2502893 8217056 ECSP_2490 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078377.1 2502477 D 544404 CDS YP_003078378.1 254793541 8217057 2503380..2503679 1 NC_013008.1 hypothetical protein 2503679 8217057 ECSP_2491 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078378.1 2503380 D 544404 CDS YP_003078379.1 254793542 8217058 2503691..2504308 1 NC_013008.1 hypothetical protein 2504308 8217058 ECSP_2492 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078379.1 2503691 D 544404 CDS YP_003078380.1 254793543 8217059 2504305..2504670 1 NC_013008.1 hypothetical protein 2504670 8217059 ECSP_2493 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078380.1 2504305 D 544404 CDS YP_003078381.1 254793544 8217060 2504677..2507499 1 NC_013008.1 replication protein for prophage CP-933T 2507499 8217060 ECSP_2494 Escherichia coli O157:H7 str. TW14359 replication protein for prophage CP-933T YP_003078381.1 2504677 D 544404 CDS YP_003078382.1 254793545 8217061 2507576..2508535 1 NC_013008.1 stability/partitioning protein encoded within prophage CP-933T 2508535 8217061 ECSP_2495 Escherichia coli O157:H7 str. TW14359 stability/partitioning protein encoded within prophage CP-933T YP_003078382.1 2507576 D 544404 CDS YP_003078383.1 254793546 8217062 2508540..2508854 1 NC_013008.1 stability/partitioning protein encoded within CP-933T 2508854 8217062 ECSP_2496 Escherichia coli O157:H7 str. TW14359 stability/partitioning protein encoded within CP-933T YP_003078383.1 2508540 D 544404 CDS YP_003078384.1 254793547 8217063 complement(2508874..2509563) 1 NC_013008.1 transposase 2509563 8217063 ECSP_2497 Escherichia coli O157:H7 str. TW14359 transposase YP_003078384.1 2508874 R 544404 CDS YP_003078385.1 254793548 8217064 complement(2509563..2509889) 1 NC_013008.1 transposase 2509889 8217064 ECSP_2498 Escherichia coli O157:H7 str. TW14359 transposase YP_003078385.1 2509563 R 544404 CDS YP_003078386.1 254793549 8217065 2510060..2510476 1 NC_013008.1 tail fiber assembly protein of prophage CP-933T 2510476 8217065 ECSP_2499 Escherichia coli O157:H7 str. TW14359 tail fiber assembly protein of prophage CP-933T YP_003078386.1 2510060 D 544404 CDS YP_003078387.1 254793550 8217066 complement(2510520..2511092) 1 NC_013008.1 serine acetlyltransferase of prophage CP-933T 2511092 8217066 ECSP_2500 Escherichia coli O157:H7 str. TW14359 serine acetlyltransferase of prophage CP-933T YP_003078387.1 2510520 R 544404 CDS YP_003078388.1 254793551 8217067 complement(2511249..2511737) 1 NC_013008.1 tail fiber protein of prophage CP-933T 2511737 8217067 ECSP_2501 Escherichia coli O157:H7 str. TW14359 tail fiber protein of prophage CP-933T YP_003078388.1 2511249 R 544404 CDS YP_003078389.1 254793552 8217069 complement(2514540..2514695) 1 NC_013008.1 tail fiber protein component of prophage CP-933T 2514695 8217069 ECSP_2503 Escherichia coli O157:H7 str. TW14359 tail fiber protein component of prophage CP-933T YP_003078389.1 2514540 R 544404 CDS YP_003078390.1 254793553 8217070 complement(2514704..2515069) 1 NC_013008.1 hypothetical protein 2515069 8217070 ECSP_2504 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078390.1 2514704 R 544404 CDS YP_003078391.1 254793554 8217071 complement(2515124..2515636) 1 NC_013008.1 tail fiber component of prophage CP-933T 2515636 8217071 ECSP_2505 Escherichia coli O157:H7 str. TW14359 tail fiber component of prophage CP-933T YP_003078391.1 2515124 R 544404 CDS YP_003078392.1 254793555 8217072 complement(2515636..2516820) 1 NC_013008.1 tail sheath protein of prophage CP-933T 2516820 8217072 ECSP_2506 Escherichia coli O157:H7 str. TW14359 tail sheath protein of prophage CP-933T YP_003078392.1 2515636 R 544404 CDS YP_003078393.1 254793556 8217073 2516948..2517301 1 NC_013008.1 tail assembly protein of prophage CP-933T 2517301 8217073 ECSP_2507 Escherichia coli O157:H7 str. TW14359 tail assembly protein of prophage CP-933T YP_003078393.1 2516948 D 544404 CDS YP_003078394.1 254793557 8217074 complement(2517252..2518181) 1 NC_013008.1 transposase, IS30 2518181 8217074 ECSP_2508 Escherichia coli O157:H7 str. TW14359 transposase, IS30 YP_003078394.1 2517252 R 544404 CDS YP_003078395.1 254793558 8217075 2518278..2518604 1 NC_013008.1 transposase 2518604 8217075 ECSP_2509 Escherichia coli O157:H7 str. TW14359 transposase YP_003078395.1 2518278 D 544404 CDS YP_003078396.1 254793559 8217076 2518604..2519491 1 NC_013008.1 transposase, IS1203 2519491 8217076 ECSP_2510 Escherichia coli O157:H7 str. TW14359 transposase, IS1203 YP_003078396.1 2518604 D 544404 CDS YP_003078397.1 254793560 8217077 complement(2519531..2519677) 1 NC_013008.1 hypothetical protein 2519677 8217077 ECSP_2511 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078397.1 2519531 R 544404 CDS YP_003078398.1 254793561 8217078 complement(2519858..2520250) 1 NC_013008.1 hypothetical protein 2520250 8217078 ECSP_2512 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078398.1 2519858 R 544404 CDS YP_003078399.1 254793562 8217082 complement(2521131..2521679) 1 NC_013008.1 phosphatidylglycerophosphate synthetase 2521679 pgsA 8217082 pgsA Escherichia coli O157:H7 str. TW14359 phosphatidylglycerophosphate synthetase YP_003078399.1 2521131 R 544404 CDS YP_003078400.1 254793563 8217083 complement(2521736..2523568) 1 NC_013008.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2523568 uvrC 8217083 uvrC Escherichia coli O157:H7 str. TW14359 excinuclease ABC subunit C YP_003078400.1 2521736 R 544404 CDS YP_003078401.1 254793564 8217084 complement(2523565..2524221) 1 NC_013008.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2524221 uvrY 8217084 uvrY Escherichia coli O157:H7 str. TW14359 response regulator YP_003078401.1 2523565 R 544404 CDS YP_003078402.1 254793565 8217085 2524680..2524904 1 NC_013008.1 hypothetical protein 2524904 yecF 8217085 yecF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078402.1 2524680 D 544404 CDS YP_003078403.1 254793566 8217086 complement(2524972..2525694) 1 NC_013008.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2525694 sdiA 8217086 sdiA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator SdiA YP_003078403.1 2524972 R 544404 CDS YP_003078404.1 254793567 8217087 complement(2525924..2526676) 1 NC_013008.1 amino-acid ABC transporter ATP-binding protein YecC 2526676 yecC 8217087 yecC Escherichia coli O157:H7 str. TW14359 amino-acid ABC transporter ATP-binding protein YecC YP_003078404.1 2525924 R 544404 CDS YP_003078405.1 254793568 8217088 complement(2526673..2527341) 1 NC_013008.1 ABC transporter membrane protein 2527341 yecS 8217088 yecS Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003078405.1 2526673 R 544404 CDS YP_003078406.1 254793569 8217089 complement(2527356..2528342) 1 NC_013008.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2528342 dcyD 8217089 dcyD Escherichia coli O157:H7 str. TW14359 D-cysteine desulfhydrase YP_003078406.1 2527356 R 544404 CDS YP_003078407.1 254793570 8217090 complement(2528447..2529247) 1 NC_013008.1 cystine transporter subunit 2529247 fliY 8217090 fliY Escherichia coli O157:H7 str. TW14359 cystine transporter subunit YP_003078407.1 2528447 R 544404 CDS YP_003078408.1 254793571 8217091 complement(2529335..2529886) 1 NC_013008.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2529886 fliZ 8217091 fliZ Escherichia coli O157:H7 str. TW14359 flagella biosynthesis protein FliZ YP_003078408.1 2529335 R 544404 CDS YP_003078409.1 254793572 8217092 complement(2529932..2530651) 1 NC_013008.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2530651 fliA 8217092 fliA Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis sigma factor YP_003078409.1 2529932 R 544404 CDS YP_003078410.1 254793573 8217093 2530725..2530844 1 NC_013008.1 hypothetical protein 2530844 8217093 ECSP_2527 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078410.1 2530725 D 544404 CDS YP_003078411.1 254793574 8217094 complement(2530971..2532728) 1 NC_013008.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2532728 fliC 8217094 fliC Escherichia coli O157:H7 str. TW14359 flagellin YP_003078411.1 2530971 R 544404 CDS YP_003078412.1 254793575 8217095 2532994..2534391 1 NC_013008.1 involved in flagellin assembly; flagellar capping protein 2534391 fliD 8217095 fliD Escherichia coli O157:H7 str. TW14359 flagellar capping protein YP_003078412.1 2532994 D 544404 CDS YP_003078413.1 254793576 8217096 2534416..2534826 1 NC_013008.1 flagellin specific chaperone; flagellar protein FliS 2534826 fliS 8217096 fliS Escherichia coli O157:H7 str. TW14359 flagellar protein FliS YP_003078413.1 2534416 D 544404 CDS YP_003078414.1 254793577 8217097 2534826..2535191 1 NC_013008.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2535191 fliT 8217097 fliT Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FliT YP_003078414.1 2534826 D 544404 CDS YP_003078415.1 254793578 8217098 2535269..2536756 1 NC_013008.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2536756 amyA 8217098 amyA Escherichia coli O157:H7 str. TW14359 cytoplasmic alpha-amylase YP_003078415.1 2535269 D 544404 CDS YP_003078416.1 254793579 8217099 complement(2536790..2537203) 1 NC_013008.1 hypothetical protein 2537203 yedD 8217099 yedD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078416.1 2536790 R 544404 CDS YP_003078417.1 254793580 8217100 2537390..2538595 1 NC_013008.1 inner membrane protein 2538595 yedE 8217100 yedE Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078417.1 2537390 D 544404 CDS YP_003078418.1 254793581 8217101 2538592..2538825 1 NC_013008.1 hypothetical protein 2538825 yedF 8217101 yedF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078418.1 2538592 D 544404 CDS YP_003078419.1 254793582 8217102 2538934..2539602 1 NC_013008.1 hypothetical protein 2539602 yedK 8217102 yedK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078419.1 2538934 D 544404 CDS YP_003078420.1 254793583 8217103 2539713..2540192 1 NC_013008.1 acyltransferase 2540192 yedL 8217103 yedL Escherichia coli O157:H7 str. TW14359 acyltransferase YP_003078420.1 2539713 D 544404 CDS YP_003078421.1 254793584 8217104 complement(2540330..2541469) 1 NC_013008.1 non-LEE-encoded type III effector 2541469 espR3 8217104 espR3 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003078421.1 2540330 R 544404 CDS YP_003078422.1 254793585 8217105 2541851..2542150 1 NC_013008.1 hypothetical protein 2542150 8217105 ECSP_2539 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078422.1 2541851 D 544404 CDS YP_003078423.1 254793586 8217106 complement(2542288..2543427) 1 NC_013008.1 non-LEE-encoded type III effector 2543427 espR4 8217106 espR4 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003078423.1 2542288 R 544404 CDS YP_003078424.1 254793587 8217107 complement(2543776..2544090) 1 NC_013008.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2544090 fliE 8217107 fliE Escherichia coli O157:H7 str. TW14359 flagellar hook-basal body protein FliE YP_003078424.1 2543776 R 544404 CDS YP_003078425.1 254793588 8217108 2544305..2545963 1 NC_013008.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2545963 fliF 8217108 fliF Escherichia coli O157:H7 str. TW14359 flagellar MS-ring protein YP_003078425.1 2544305 D 544404 CDS YP_003078426.1 254793589 8217109 2545956..2546951 1 NC_013008.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2546951 fliG 8217109 fliG Escherichia coli O157:H7 str. TW14359 flagellar motor switch protein G YP_003078426.1 2545956 D 544404 CDS YP_003078427.1 254793590 8217110 2546944..2547630 1 NC_013008.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2547630 fliH 8217110 fliH Escherichia coli O157:H7 str. TW14359 flagellar assembly protein H YP_003078427.1 2546944 D 544404 CDS YP_003078428.1 254793591 8217111 2547692..2549065 1 NC_013008.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2549065 fliI 8217111 fliI Escherichia coli O157:H7 str. TW14359 flagellum-specific ATP synthase YP_003078428.1 2547692 D 544404 CDS YP_003078429.1 254793592 8217112 2549084..2549527 1 NC_013008.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2549527 fliJ 8217112 fliJ Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis chaperone YP_003078429.1 2549084 D 544404 CDS YP_003078430.1 254793593 8217113 2549524..2550651 1 NC_013008.1 flagellar hook-length control protein 2550651 fliK 8217113 fliK Escherichia coli O157:H7 str. TW14359 flagellar hook-length control protein YP_003078430.1 2549524 D 544404 CDS YP_003078431.1 254793594 8217114 2550756..2551220 1 NC_013008.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2551220 fliL 8217114 fliL Escherichia coli O157:H7 str. TW14359 flagellar basal body-associated protein FliL YP_003078431.1 2550756 D 544404 CDS YP_003078432.1 254793595 8217115 2551225..2552229 1 NC_013008.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2552229 fliM 8217115 fliM Escherichia coli O157:H7 str. TW14359 flagellar motor switch protein FliM YP_003078432.1 2551225 D 544404 CDS YP_003078433.1 254793596 8217116 2552226..2552639 1 NC_013008.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2552639 fliN 8217116 fliN Escherichia coli O157:H7 str. TW14359 flagellar motor switch protein FliN YP_003078433.1 2552226 D 544404 CDS YP_003078434.1 254793597 8217117 2552642..2553007 1 NC_013008.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2553007 fliO 8217117 fliO Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FliO YP_003078434.1 2552642 D 544404 CDS YP_003078435.1 254793598 8217118 2553007..2553744 1 NC_013008.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2553744 fliP 8217118 fliP Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FliP YP_003078435.1 2553007 D 544404 CDS YP_003078436.1 254793599 8217119 2553754..2554023 1 NC_013008.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2554023 fliQ 8217119 fliQ Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FliQ YP_003078436.1 2553754 D 544404 CDS YP_003078437.1 254793600 8217120 2554031..2554816 1 NC_013008.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2554816 fliR 8217120 fliR Escherichia coli O157:H7 str. TW14359 flagellar biosynthesis protein FliR YP_003078437.1 2554031 D 544404 CDS YP_003078438.1 254793601 8217121 2555106..2555729 1 NC_013008.1 DNA-binding transcriptional activator, co-regulator with RcsB 2555729 rcsA 8217121 rcsA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator, co-regulator with RcsB YP_003078438.1 2555106 D 544404 CDS YP_003078439.1 254793602 8217122 complement(2555773..2555961) 1 NC_013008.1 hypothetical protein 2555961 dsrB 8217122 dsrB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078439.1 2555773 R 544404 CDS YP_003078440.1 254793603 8217123 2556124..2556351 1 NC_013008.1 hypothetical protein 2556351 yodD 8217123 yodD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078440.1 2556124 D 544404 CDS YP_003078441.1 254793604 8217124 2556397..2556507 1 NC_013008.1 hypothetical protein 2556507 8217124 ECSP_2558 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078441.1 2556397 D 544404 CDS YP_003078442.1 254793605 8217125 2556649..2557464 1 NC_013008.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2557464 yedP 8217125 yedP Escherichia coli O157:H7 str. TW14359 mannosyl-3-phosphoglycerate phosphatase YP_003078442.1 2556649 D 544404 CDS YP_003078443.1 254793606 8217126 complement(2557461..2559155) 1 NC_013008.1 diguanylate cyclase 2559155 yedQ 8217126 yedQ Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003078443.1 2557461 R 544404 CDS YP_003078444.1 254793607 8217127 complement(2559326..2559508) 1 NC_013008.1 hypothetical protein 2559508 yodC 8217127 yodC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078444.1 2559326 R 544404 CDS YP_003078445.1 254793608 8217128 complement(2559587..2560504) 1 NC_013008.1 hypothetical protein 2560504 yedI 8217128 yedI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078445.1 2559587 R 544404 CDS YP_003078446.1 254793609 8217129 2560677..2561597 1 NC_013008.1 hypothetical protein 2561597 yedA 8217129 yedA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078446.1 2560677 D 544404 CDS YP_003078447.1 254793610 8217130 complement(2561586..2562056) 1 NC_013008.1 DNA mismatch endonuclease of very short patch repair 2562056 vsr 8217130 vsr Escherichia coli O157:H7 str. TW14359 DNA mismatch endonuclease of very short patch repair YP_003078447.1 2561586 R 544404 CDS YP_003078448.1 254793611 8217131 complement(2562037..2563455) 1 NC_013008.1 DNA cytosine methylase 2563455 dcm 8217131 dcm Escherichia coli O157:H7 str. TW14359 DNA cytosine methylase YP_003078448.1 2562037 R 544404 CDS YP_003078449.1 254793612 8217132 complement(2563522..2564217) 1 NC_013008.1 hypothetical protein 2564217 yedJ 8217132 yedJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078449.1 2563522 R 544404 CDS YP_003078450.1 254793613 8217133 complement(2564313..2564621) 1 NC_013008.1 inner membrane protein 2564621 yedR 8217133 yedR Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078450.1 2564313 R 544404 CDS YP_003078451.1 254793614 8217134 2564804..2564917 1 NC_013008.1 hypothetical protein 2564917 8217134 ECSP_2568 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078451.1 2564804 D 544404 CDS YP_003078452.1 254793615 8217135 2565188..2565832 1 NC_013008.1 outer membrane protein 2565832 8217135 ECSP_2569 Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003078452.1 2565188 D 544404 CDS YP_003078453.1 254793616 8217136 2565799..2566374 1 NC_013008.1 outer membrane protein 2566374 8217136 ECSP_2570 Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003078453.1 2565799 D 544404 CDS YP_003078454.1 254793617 8217137 complement(2566583..2566786) 1 NC_013008.1 hypothetical protein 2566786 8217137 ECSP_2571 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078454.1 2566583 R 544404 CDS YP_003078455.1 254793618 8217138 2566802..2566945 1 NC_013008.1 hypothetical protein 2566945 8217138 ECSP_2572 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078455.1 2566802 D 544404 CDS YP_003078456.1 254793619 8217139 2566966..2567817 1 NC_013008.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2567817 hchA 8217139 hchA Escherichia coli O157:H7 str. TW14359 chaperone protein HchA YP_003078456.1 2566966 D 544404 CDS YP_003078457.1 254793620 8217140 complement(2567925..2569283) 1 NC_013008.1 sensory kinase in two-component regulatory system with YedW 2569283 yedV 8217140 yedV Escherichia coli O157:H7 str. TW14359 sensory kinase in two-component regulatory system with YedW YP_003078457.1 2567925 R 544404 CDS YP_003078458.1 254793621 8217141 complement(2569283..2569954) 1 NC_013008.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2569954 yedW 8217141 yedW Escherichia coli O157:H7 str. TW14359 transcriptional regulatory protein YedW YP_003078458.1 2569283 R 544404 CDS YP_003078459.1 254793622 8217142 2570087..2570500 1 NC_013008.1 hypothetical protein 2570500 yedX 8217142 yedX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078459.1 2570087 D 544404 CDS YP_003078460.1 254793623 8217143 2570608..2571612 1 NC_013008.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2571612 yedY 8217143 yedY Escherichia coli O157:H7 str. TW14359 sulfite oxidase subunit YedY YP_003078460.1 2570608 D 544404 CDS YP_003078461.1 254793624 8217144 2571613..2572248 1 NC_013008.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2572248 yedZ 8217144 yedZ Escherichia coli O157:H7 str. TW14359 sulfite oxidase subunit YedZ YP_003078461.1 2571613 D 544404 CDS YP_003078462.1 254793625 8217145 2572505..2573155 1 NC_013008.1 hypothetical protein 2573155 yodA 8217145 yodA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078462.1 2572505 D 544404 CDS YP_003078463.1 254793626 8217146 2573265..2573414 1 NC_013008.1 hypothetical protein 2573414 8217146 ECSP_2580 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078463.1 2573265 D 544404 CDS YP_003078464.1 254793627 8217147 2573498..2574028 1 NC_013008.1 cytochrome 2574028 yodB 8217147 yodB Escherichia coli O157:H7 str. TW14359 cytochrome YP_003078464.1 2573498 D 544404 CDS YP_003078465.1 254793628 8217148 2574598..2574957 1 NC_013008.1 hypothetical protein 2574957 8217148 ECSP_2582 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078465.1 2574598 D 544404 CDS YP_003078466.1 254793629 8217149 2575299..2575817 1 NC_013008.1 translocated type III secretion system effector 2575817 espJ 8217149 espJ Escherichia coli O157:H7 str. TW14359 translocated type III secretion system effector YP_003078466.1 2575299 D 544404 CDS YP_003078467.1 254793630 8217150 2576142..2577155 1 NC_013008.1 Tir-cytoskeleton coupling protein (TccP) 2577155 tccP 8217150 tccP Escherichia coli O157:H7 str. TW14359 Tir-cytoskeleton coupling protein (TccP) YP_003078467.1 2576142 D 544404 CDS YP_003078468.1 254793631 8217151 complement(2577281..2577550) 1 NC_013008.1 tail fiber protein 2577550 8217151 ECSP_2585 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003078468.1 2577281 R 544404 CDS YP_003078469.1 254793632 8217152 complement(2577552..2578865) 1 NC_013008.1 tail fiber protein 2578865 8217152 ECSP_2586 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003078469.1 2577552 R 544404 CDS YP_003078470.1 254793633 8217153 complement(2578930..2579529) 1 NC_013008.1 Ail/Lom family protein 2579529 8217153 ECSP_2587 Escherichia coli O157:H7 str. TW14359 Ail/Lom family protein YP_003078470.1 2578930 R 544404 CDS YP_003078471.1 254793634 8217155 complement(2583317..2583895) 1 NC_013008.1 tail assembly protein 2583895 8217155 ECSP_2589 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003078471.1 2583317 R 544404 CDS YP_003078472.1 254793635 8217156 complement(2583892..2584527) 1 NC_013008.1 tail fiber component 2584527 8217156 ECSP_2590 Escherichia coli O157:H7 str. TW14359 tail fiber component YP_003078472.1 2583892 R 544404 CDS YP_003078473.1 254793636 8217157 complement(2584646..2585344) 1 NC_013008.1 minor tail protein L 2585344 8217157 ECSP_2591 Escherichia coli O157:H7 str. TW14359 minor tail protein L YP_003078473.1 2584646 R 544404 CDS YP_003078474.1 254793637 8217158 complement(2585344..2585673) 1 NC_013008.1 phage minor tail protein 2585673 8217158 ECSP_2592 Escherichia coli O157:H7 str. TW14359 phage minor tail protein YP_003078474.1 2585344 R 544404 CDS YP_003078475.1 254793638 8217159 complement(2585670..2588249) 1 NC_013008.1 tail length tape measure protein 2588249 8217159 ECSP_2593 Escherichia coli O157:H7 str. TW14359 tail length tape measure protein YP_003078475.1 2585670 R 544404 CDS YP_003078476.1 254793639 8217160 complement(2588230..2588643) 1 NC_013008.1 tail component of prophage CP-933R 2588643 8217160 ECSP_2594 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933R YP_003078476.1 2588230 R 544404 CDS YP_003078477.1 254793640 8217161 complement(2588670..2589173) 1 NC_013008.1 tail component of prophage CP-933R 2589173 8217161 ECSP_2595 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933R YP_003078477.1 2588670 R 544404 CDS YP_003078478.1 254793641 8217162 complement(2589115..2589777) 1 NC_013008.1 tail component of prophage CP-933R 2589777 8217162 ECSP_2596 Escherichia coli O157:H7 str. TW14359 tail component of prophage CP-933R YP_003078478.1 2589115 R 544404 CDS YP_003078479.1 254793642 8217163 complement(2589837..2590103) 1 NC_013008.1 capsid structural protein of prophage CP-933R 2590103 8217163 ECSP_2597 Escherichia coli O157:H7 str. TW14359 capsid structural protein of prophage CP-933R YP_003078479.1 2589837 R 544404 CDS YP_003078480.1 254793643 8217164 complement(2590161..2590508) 1 NC_013008.1 capsid protein of prophage CP-933R 2590508 8217164 ECSP_2598 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage CP-933R YP_003078480.1 2590161 R 544404 CDS YP_003078481.1 254793644 8217165 complement(2590545..2592050) 1 NC_013008.1 capsid assembly protein of prophage CP-933R 2592050 8217165 ECSP_2599 Escherichia coli O157:H7 str. TW14359 capsid assembly protein of prophage CP-933R YP_003078481.1 2590545 R 544404 CDS YP_003078482.1 254793645 8217166 complement(2592040..2593632) 1 NC_013008.1 capsid protein of prophage CP-933R 2593632 8217166 ECSP_2600 Escherichia coli O157:H7 str. TW14359 capsid protein of prophage CP-933R YP_003078482.1 2592040 R 544404 CDS YP_003078483.1 254793646 8217167 complement(2593629..2593769) 1 NC_013008.1 DNA packaging protein of prophage CP-933R 2593769 8217167 ECSP_2601 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933R YP_003078483.1 2593629 R 544404 CDS YP_003078484.1 254793647 8217168 complement(2593819..2595510) 1 NC_013008.1 DNA packaging protein of prophage CP-933R; terminase large subunit 2595510 8217168 ECSP_2602 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933R; terminase large subunit YP_003078484.1 2593819 R 544404 CDS YP_003078485.1 254793648 8217169 complement(2595720..2596229) 1 NC_013008.1 DNA packaging protein of prophage CP-933R; terminase small subunit 2596229 8217169 ECSP_2603 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933R; terminase small subunit YP_003078485.1 2595720 R 544404 CDS YP_003078486.1 254793649 8217170 2596624..2596848 1 NC_013008.1 hypothetical protein 2596848 8217170 ECSP_2604 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078486.1 2596624 D 544404 CDS YP_003078487.1 254793650 8217171 2597247..2597360 1 NC_013008.1 hypothetical protein 2597360 8217171 ECSP_2605 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078487.1 2597247 D 544404 CDS YP_003078488.1 254793651 8217172 complement(2597486..2597626) 1 NC_013008.1 hypothetical protein 2597626 8217172 ECSP_2606 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078488.1 2597486 R 544404 CDS YP_003078489.1 254793652 8217173 complement(2597709..2598176) 1 NC_013008.1 endopeptidase Rz of prophage CP-933R 2598176 8217173 ECSP_2607 Escherichia coli O157:H7 str. TW14359 endopeptidase Rz of prophage CP-933R YP_003078489.1 2597709 R 544404 CDS YP_003078490.1 254793653 8217174 complement(2598328..2598510) 1 NC_013008.1 hypothetical protein 2598510 8217174 ECSP_2608 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078490.1 2598328 R 544404 CDS YP_003078491.1 254793654 8217175 complement(2598666..2599199) 1 NC_013008.1 lysozyme R of prophage CP-933R 2599199 8217175 ECSP_2609 Escherichia coli O157:H7 str. TW14359 lysozyme R of prophage CP-933R YP_003078491.1 2598666 R 544404 CDS YP_003078492.1 254793655 8217176 complement(2599250..2599594) 1 NC_013008.1 hypothetical protein 2599594 8217176 ECSP_2610 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078492.1 2599250 R 544404 CDS YP_003078493.1 254793656 8217177 complement(2599599..2599805) 1 NC_013008.1 hypothetical protein 2599805 8217177 ECSP_2611 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078493.1 2599599 R 544404 CDS YP_003078494.1 254793657 8217178 2600125..2600451 1 NC_013008.1 transposase 2600451 8217178 ECSP_2612 Escherichia coli O157:H7 str. TW14359 transposase YP_003078494.1 2600125 D 544404 CDS YP_003078495.1 254793658 8217179 2600448..2601338 1 NC_013008.1 transposase 2601338 8217179 ECSP_2613 Escherichia coli O157:H7 str. TW14359 transposase YP_003078495.1 2600448 D 544404 CDS YP_003078496.1 254793659 8217180 complement(2601420..2603270) 1 NC_013008.1 hypothetical protein 2603270 8217180 ECSP_2614 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078496.1 2601420 R 544404 CDS YP_003078497.1 254793660 8217181 complement(2603584..2603751) 1 NC_013008.1 hypothetical protein 2603751 8217181 ECSP_2615 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078497.1 2603584 R 544404 CDS YP_003078498.1 254793661 8217182 complement(2603748..2604176) 1 NC_013008.1 hypothetical protein 2604176 8217182 ECSP_2616 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078498.1 2603748 R 544404 CDS YP_003078499.1 254793662 8217186 complement(2604810..2605499) 1 NC_013008.1 antiterminator Q-like protein of prophage CP-933U 2605499 8217186 ECSP_2620 Escherichia coli O157:H7 str. TW14359 antiterminator Q-like protein of prophage CP-933U YP_003078499.1 2604810 R 544404 CDS YP_003078500.1 254793663 8217187 complement(2605496..2605855) 1 NC_013008.1 endonuclease encoded within prophage CP-933U 2605855 8217187 ECSP_2621 Escherichia coli O157:H7 str. TW14359 endonuclease encoded within prophage CP-933U YP_003078500.1 2605496 R 544404 CDS YP_003078501.1 254793664 8217188 complement(2605868..2606917) 1 NC_013008.1 hypothetical protein 2606917 8217188 ECSP_2622 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078501.1 2605868 R 544404 CDS YP_003078502.1 254793665 8217189 complement(2606919..2607197) 1 NC_013008.1 hypothetical protein 2607197 8217189 ECSP_2623 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078502.1 2606919 R 544404 CDS YP_003078503.1 254793666 8217190 complement(2607764..2607913) 1 NC_013008.1 hypothetical protein 2607913 8217190 ECSP_2624 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078503.1 2607764 R 544404 CDS YP_003078504.1 254793667 8217191 complement(2607978..2608541) 1 NC_013008.1 hypothetical protein 2608541 8217191 ECSP_2625 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078504.1 2607978 R 544404 CDS YP_003078505.1 254793668 8217192 complement(2608668..2608979) 1 NC_013008.1 hypothetical protein 2608979 8217192 ECSP_2626 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078505.1 2608668 R 544404 CDS YP_003078506.1 254793669 8217193 complement(2609161..2609517) 1 NC_013008.1 hypothetical protein 2609517 8217193 ECSP_2627 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078506.1 2609161 R 544404 CDS YP_003078507.1 254793670 8217194 complement(2609760..2610458) 1 NC_013008.1 hypothetical protein 2610458 8217194 ECSP_2628 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078507.1 2609760 R 544404 CDS YP_003078508.1 254793671 8217195 complement(2610493..2610915) 1 NC_013008.1 hypothetical protein 2610915 8217195 ECSP_2629 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078508.1 2610493 R 544404 CDS YP_003078509.1 254793672 8217196 complement(2610947..2611984) 1 NC_013008.1 hypothetical protein 2611984 8217196 ECSP_2630 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078509.1 2610947 R 544404 CDS YP_003078510.1 254793673 8217197 complement(2612053..2612478) 1 NC_013008.1 hypothetical protein 2612478 8217197 ECSP_2631 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078510.1 2612053 R 544404 CDS YP_003078511.1 254793674 8217198 2612797..2613444 1 NC_013008.1 repressor protein of prophage CP-933U 2613444 8217198 ECSP_2632 Escherichia coli O157:H7 str. TW14359 repressor protein of prophage CP-933U YP_003078511.1 2612797 D 544404 CDS YP_003078512.1 254793675 8217199 2613719..2613871 1 NC_013008.1 hypothetical protein 2613871 8217199 ECSP_2633 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078512.1 2613719 D 544404 CDS YP_003078513.1 254793676 8217200 2614352..2614540 1 NC_013008.1 hypothetical protein 2614540 8217200 ECSP_2634 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078513.1 2614352 D 544404 CDS YP_003078514.1 254793677 8217201 2614537..2614725 1 NC_013008.1 hypothetical protein 2614725 8217201 ECSP_2635 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078514.1 2614537 D 544404 CDS YP_003078515.1 254793678 8217202 2614821..2617292 1 NC_013008.1 exodeoxyribonuclease VIII of prophage CP-933U 2617292 exoU 8217202 exoU Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease VIII of prophage CP-933U YP_003078515.1 2614821 D 544404 CDS YP_003078516.1 254793679 8217203 2617554..2618633 1 NC_013008.1 integrase for prophage CP-933U 2618633 intU 8217203 intU Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933U YP_003078516.1 2617554 D 544404 CDS YP_003078517.1 254793680 8217205 2618825..2619622 1 NC_013008.1 hypothetical protein 2619622 mtfA 8217205 mtfA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078517.1 2618825 D 544404 CDS YP_003078518.1 254793681 8217207 2620085..2628094 1 NC_013008.1 adhesin 2628094 yeeJ 8217207 yeeJ Escherichia coli O157:H7 str. TW14359 adhesin YP_003078518.1 2620085 D 544404 CDS YP_003078519.1 254793682 8217208 complement(2628356..2629408) 1 NC_013008.1 hypothetical protein 2629408 8217208 ECSP_2642 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078519.1 2628356 R 544404 CDS YP_003078520.1 254793683 8217209 2629722..2631038 1 NC_013008.1 shikimate transporter 2631038 shiA 8217209 shiA Escherichia coli O157:H7 str. TW14359 shikimate transporter YP_003078520.1 2629722 D 544404 CDS YP_003078521.1 254793684 8217210 2631140..2632594 1 NC_013008.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2632594 amn 8217210 amn Escherichia coli O157:H7 str. TW14359 AMP nucleosidase YP_003078521.1 2631140 D 544404 CDS YP_003078522.1 254793685 8217211 2632937..2633653 1 NC_013008.1 hypothetical protein 2633653 yeeN 8217211 yeeN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078522.1 2632937 D 544404 CDS YP_003078523.1 254793686 8217212 complement(2633698..2633880) 1 NC_013008.1 hypothetical protein 2633880 8217212 ECSP_2646 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078523.1 2633698 R 544404 CDS YP_003078524.1 254793687 8217213 2633947..2634063 1 NC_013008.1 hypothetical protein 2634063 8217213 ECSP_2647 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078524.1 2633947 D 544404 CDS YP_003078525.1 254793688 8217215 complement(2634279..2635766) 1 NC_013008.1 hypothetical protein 2635766 8217215 ECSP_2649 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078525.1 2634279 R 544404 CDS YP_003078526.1 254793689 8217217 complement(2636040..2636990) 1 NC_013008.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2636990 cbl 8217217 cbl Escherichia coli O157:H7 str. TW14359 transcriptional regulator Cbl YP_003078526.1 2636040 R 544404 CDS YP_003078527.1 254793690 8217218 complement(2637092..2638009) 1 NC_013008.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2638009 nac 8217218 nac Escherichia coli O157:H7 str. TW14359 nitrogen assimilation transcriptional regulator YP_003078527.1 2637092 R 544404 CDS YP_003078528.1 254793691 8217219 2638197..2638313 1 NC_013008.1 hypothetical protein 2638313 8217219 ECSP_2653 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078528.1 2638197 D 544404 CDS YP_003078529.1 254793692 8217221 complement(2638466..2639398) 1 NC_013008.1 hypothetical protein 2639398 erfK 8217221 erfK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078529.1 2638466 R 544404 CDS YP_003078530.1 254793693 8217222 complement(2639463..2640542) 1 NC_013008.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2640542 cobT 8217222 cobT Escherichia coli O157:H7 str. TW14359 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_003078530.1 2639463 R 544404 CDS YP_003078531.1 254793694 8217223 complement(2640554..2641297) 1 NC_013008.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2641297 cobS 8217223 cobS Escherichia coli O157:H7 str. TW14359 cobalamin synthase YP_003078531.1 2640554 R 544404 CDS YP_003078532.1 254793695 8217224 complement(2641294..2641839) 1 NC_013008.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase 2641839 cobU 8217224 cobU Escherichia coli O157:H7 str. TW14359 adenosylcobinamide kinase YP_003078532.1 2641294 R 544404 CDS YP_003078533.1 254793696 8217225 2642180..2642581 1 NC_013008.1 transposase, ISEc8 2642581 8217225 ECSP_2659 Escherichia coli O157:H7 str. TW14359 transposase, ISEc8 YP_003078533.1 2642180 D 544404 CDS YP_003078534.1 254793697 8217226 2642578..2642925 1 NC_013008.1 transposase 2642925 8217226 ECSP_2660 Escherichia coli O157:H7 str. TW14359 transposase YP_003078534.1 2642578 D 544404 CDS YP_003078535.1 254793698 8217227 2642975..2644513 1 NC_013008.1 transposase, ISEc8 2644513 8217227 ECSP_2661 Escherichia coli O157:H7 str. TW14359 transposase, ISEc8 YP_003078535.1 2642975 D 544404 CDS YP_003078536.1 254793699 8217228 complement(2644754..2644918) 1 NC_013008.1 hypothetical protein 2644918 8217228 ECSP_2662 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078536.1 2644754 R 544404 CDS YP_003078537.1 254793700 8217229 complement(2645331..2646221) 1 NC_013008.1 transposase 2646221 8217229 ECSP_2663 Escherichia coli O157:H7 str. TW14359 transposase YP_003078537.1 2645331 R 544404 CDS YP_003078538.1 254793701 8217230 complement(2646218..2646544) 1 NC_013008.1 transposase 2646544 8217230 ECSP_2664 Escherichia coli O157:H7 str. TW14359 transposase YP_003078538.1 2646218 R 544404 CDS YP_003078539.1 254793702 8217231 2647274..2649421 1 NC_013008.1 outer membrane receptor for iron compound or colicin 2649421 8217231 ECSP_2665 Escherichia coli O157:H7 str. TW14359 outer membrane receptor for iron compound or colicin YP_003078539.1 2647274 D 544404 CDS YP_003078540.1 254793703 8217232 2649874..2650557 1 NC_013008.1 hypothetical protein 2650557 8217232 ECSP_2666 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078540.1 2649874 D 544404 CDS YP_003078541.1 254793704 8217233 2650554..2651459 1 NC_013008.1 hypothetical protein 2651459 8217233 ECSP_2667 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078541.1 2650554 D 544404 CDS YP_003078542.1 254793705 8217234 2651456..2652526 1 NC_013008.1 hypothetical protein 2652526 8217234 ECSP_2668 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078542.1 2651456 D 544404 CDS YP_003078543.1 254793706 8217235 2652662..2653345 1 NC_013008.1 hypothetical protein 2653345 8217235 ECSP_2669 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078543.1 2652662 D 544404 CDS YP_003078544.1 254793707 8217236 2653361..2653771 1 NC_013008.1 hypothetical protein 2653771 8217236 ECSP_2670 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078544.1 2653361 D 544404 CDS YP_003078545.1 254793708 8217237 2653992..2654813 1 NC_013008.1 hypothetical protein 2654813 8217237 ECSP_2671 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078545.1 2653992 D 544404 CDS YP_003078546.1 254793709 8217238 2654895..2655374 1 NC_013008.1 antirestriction protein 2655374 8217238 ECSP_2672 Escherichia coli O157:H7 str. TW14359 antirestriction protein YP_003078546.1 2654895 D 544404 CDS YP_003078547.1 254793710 8217239 2655389..2655865 1 NC_013008.1 DNA repair protein 2655865 8217239 ECSP_2673 Escherichia coli O157:H7 str. TW14359 DNA repair protein YP_003078547.1 2655389 D 544404 CDS YP_003078548.1 254793711 8217240 2655928..2656149 1 NC_013008.1 CP4-44 prophage protein 2656149 yeeT 8217240 yeeT Escherichia coli O157:H7 str. TW14359 CP4-44 prophage protein YP_003078548.1 2655928 D 544404 CDS YP_003078549.1 254793712 8217241 2656223..2656591 1 NC_013008.1 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 2656591 yeeU 8217241 yeeU Escherichia coli O157:H7 str. TW14359 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system YP_003078549.1 2656223 D 544404 CDS YP_003078550.1 254793713 8217242 2656680..2656943 1 NC_013008.1 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system 2656943 yeeV 8217242 yeeV Escherichia coli O157:H7 str. TW14359 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system YP_003078550.1 2656680 D 544404 CDS YP_003078551.1 254793714 8217243 2657050..2657244 1 NC_013008.1 CP4-44 prophage protein 2657244 yeeW 8217243 yeeW Escherichia coli O157:H7 str. TW14359 CP4-44 prophage protein YP_003078551.1 2657050 D 544404 CDS YP_003078552.1 254793715 8217244 2657257..2657370 1 NC_013008.1 hypothetical protein 2657370 8217244 ECSP_2678 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078552.1 2657257 D 544404 CDS YP_003078553.1 254793716 8217245 2657685..2658041 1 NC_013008.1 hypothetical protein 2658041 8217245 ECSP_2679 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078553.1 2657685 D 544404 CDS YP_003078554.1 254793717 8217246 complement(2658142..2658471) 1 NC_013008.1 hypothetical protein 2658471 yeeX 8217246 yeeX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078554.1 2658142 R 544404 CDS YP_003078555.1 254793718 8217247 complement(2658643..2659701) 1 NC_013008.1 hypothetical protein 2659701 yeeA 8217247 yeeA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078555.1 2658643 R 544404 CDS YP_003078556.1 254793719 8217248 complement(2659900..2660373) 1 NC_013008.1 DNA gyrase inhibitor 2660373 sbmC 8217248 sbmC Escherichia coli O157:H7 str. TW14359 DNA gyrase inhibitor YP_003078556.1 2659900 R 544404 CDS YP_003078557.1 254793720 8217249 complement(2660492..2661658) 1 NC_013008.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2661658 dacD 8217249 dacD Escherichia coli O157:H7 str. TW14359 D-alanyl-D-alanine carboxypeptidase YP_003078557.1 2660492 R 544404 CDS YP_003078558.1 254793721 8217250 2661819..2661929 1 NC_013008.1 hypothetical protein 2661929 8217250 ECSP_2684 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078558.1 2661819 D 544404 CDS YP_003078559.1 254793722 8217251 2662713..2662997 1 NC_013008.1 hypothetical protein 2662997 8217251 ECSP_2685 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078559.1 2662713 D 544404 CDS YP_003078560.1 254793723 8217252 2662982..2663632 1 NC_013008.1 hypothetical protein 2663632 8217252 ECSP_2686 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078560.1 2662982 D 544404 CDS YP_003078561.1 254793724 8217253 complement(2663856..2664731) 1 NC_013008.1 OspB-like virulence factor 2664731 8217253 ECSP_2687 Escherichia coli O157:H7 str. TW14359 OspB-like virulence factor YP_003078561.1 2663856 R 544404 CDS YP_003078562.1 254793725 8217254 complement(2664872..2665141) 1 NC_013008.1 tail fiber protein 2665141 8217254 ECSP_2688 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003078562.1 2664872 R 544404 CDS YP_003078563.1 254793726 8217255 complement(2665143..2666456) 1 NC_013008.1 side tail fiber protein 2666456 8217255 ECSP_2689 Escherichia coli O157:H7 str. TW14359 side tail fiber protein YP_003078563.1 2665143 R 544404 CDS YP_003078564.1 254793727 8217256 complement(2666521..2667120) 1 NC_013008.1 opacity protein opA58 2667120 lomU 8217256 lomU Escherichia coli O157:H7 str. TW14359 opacity protein opA58 YP_003078564.1 2666521 R 544404 CDS YP_003078565.1 254793728 8217257 complement(2667188..2670667) 1 NC_013008.1 host specificity protein J 2670667 vhsJ 8217257 vhsJ Escherichia coli O157:H7 str. TW14359 host specificity protein J YP_003078565.1 2667188 R 544404 CDS YP_003078566.1 254793729 8217258 complement(2670906..2671586) 1 NC_013008.1 tail assembly protein I 2671586 8217258 ECSP_2692 Escherichia coli O157:H7 str. TW14359 tail assembly protein I YP_003078566.1 2670906 R 544404 CDS YP_003078567.1 254793730 8217259 complement(2671484..2672221) 1 NC_013008.1 tail assembly protein 2672221 8217259 ECSP_2693 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003078567.1 2671484 R 544404 CDS YP_003078568.1 254793731 8217260 complement(2672276..2673280) 1 NC_013008.1 antirepressor-like protein 2673280 8217260 ECSP_2694 Escherichia coli O157:H7 str. TW14359 antirepressor-like protein YP_003078568.1 2672276 R 544404 CDS YP_003078569.1 254793732 8217261 complement(2673270..2673443) 1 NC_013008.1 hypothetical protein 2673443 8217261 ECSP_2695 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078569.1 2673270 R 544404 CDS YP_003078570.1 254793733 8217262 2673527..2673871 1 NC_013008.1 hypothetical protein 2673871 8217262 ECSP_2696 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078570.1 2673527 D 544404 CDS YP_003078571.1 254793734 8217264 complement(2674614..2674955) 1 NC_013008.1 minor tail protein M 2674955 8217264 ECSP_2698 Escherichia coli O157:H7 str. TW14359 minor tail protein M YP_003078571.1 2674614 R 544404 CDS YP_003078572.1 254793735 8217265 complement(2674948..2678190) 1 NC_013008.1 minor tail protein H 2678190 8217265 ECSP_2699 Escherichia coli O157:H7 str. TW14359 minor tail protein H YP_003078572.1 2674948 R 544404 CDS YP_003078573.1 254793736 8217266 complement(2678242..2678523) 1 NC_013008.1 phage-tail protein 2678523 8217266 ECSP_2700 Escherichia coli O157:H7 str. TW14359 phage-tail protein YP_003078573.1 2678242 R 544404 CDS YP_003078574.1 254793737 8217267 complement(2678547..2678921) 1 NC_013008.1 tail assembly chaperone 2678921 8217267 ECSP_2701 Escherichia coli O157:H7 str. TW14359 tail assembly chaperone YP_003078574.1 2678547 R 544404 CDS YP_003078575.1 254793738 8217268 complement(2678927..2679643) 1 NC_013008.1 major tail subunit 2679643 8217268 ECSP_2702 Escherichia coli O157:H7 str. TW14359 major tail subunit YP_003078575.1 2678927 R 544404 CDS YP_003078576.1 254793739 8217269 complement(2679702..2680046) 1 NC_013008.1 hypothetical protein 2680046 8217269 ECSP_2703 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078576.1 2679702 R 544404 CDS YP_003078577.1 254793740 8217270 complement(2680043..2680489) 1 NC_013008.1 hypothetical protein 2680489 8217270 ECSP_2704 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078577.1 2680043 R 544404 CDS YP_003078578.1 254793741 8217271 complement(2680486..2680836) 1 NC_013008.1 bacteriophage head-tail adaptor 2680836 8217271 ECSP_2705 Escherichia coli O157:H7 str. TW14359 bacteriophage head-tail adaptor YP_003078578.1 2680486 R 544404 CDS YP_003078579.1 254793742 8217272 complement(2680846..2681172) 1 NC_013008.1 hypothetical protein 2681172 8217272 ECSP_2706 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078579.1 2680846 R 544404 CDS YP_003078580.1 254793743 8217273 complement(2681252..2683753) 1 NC_013008.1 portal protein (GP3) 2683753 8217273 ECSP_2707 Escherichia coli O157:H7 str. TW14359 portal protein (GP3) YP_003078580.1 2681252 R 544404 CDS YP_003078581.1 254793744 8217274 complement(2683965..2685902) 1 NC_013008.1 major head protein Gp17 2685902 8217274 ECSP_2708 Escherichia coli O157:H7 str. TW14359 major head protein Gp17 YP_003078581.1 2683965 R 544404 CDS YP_003078582.1 254793745 8217275 complement(2685966..2687627) 1 NC_013008.1 phage terminase large subunit 2687627 terL 8217275 terL Escherichia coli O157:H7 str. TW14359 phage terminase large subunit YP_003078582.1 2685966 R 544404 CDS YP_003078583.1 254793746 8217276 complement(2687624..2688187) 1 NC_013008.1 PBSX phage terminase small subunit 2688187 terS 8217276 terS Escherichia coli O157:H7 str. TW14359 PBSX phage terminase small subunit YP_003078583.1 2687624 R 544404 CDS YP_003078584.1 254793747 8217277 complement(2688251..2688352) 1 NC_013008.1 hypothetical protein 2688352 8217277 ECSP_2711 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078584.1 2688251 R 544404 CDS YP_003078585.1 254793748 8217278 complement(2688479..2688844) 1 NC_013008.1 restriction endonuclease 2688844 8217278 ECSP_2712 Escherichia coli O157:H7 str. TW14359 restriction endonuclease YP_003078585.1 2688479 R 544404 CDS YP_003078586.1 254793749 8217279 2688886..2689113 1 NC_013008.1 hypothetical protein 2689113 8217279 ECSP_2713 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078586.1 2688886 D 544404 CDS YP_003078587.1 254793750 8217280 complement(2689576..2689833) 1 NC_013008.1 hypothetical protein 2689833 8217280 ECSP_2714 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078587.1 2689576 R 544404 CDS YP_003078588.1 254793751 8217281 complement(2689830..2690327) 1 NC_013008.1 KilA-N domain family protein 2690327 kilA 8217281 kilA Escherichia coli O157:H7 str. TW14359 KilA-N domain family protein YP_003078588.1 2689830 R 544404 CDS YP_003078589.1 254793752 8217282 complement(2690530..2690967) 1 NC_013008.1 Rz lysis family protein 2690967 8217282 ECSP_2716 Escherichia coli O157:H7 str. TW14359 Rz lysis family protein YP_003078589.1 2690530 R 544404 CDS YP_003078590.1 254793753 8217283 complement(2690964..2691461) 1 NC_013008.1 phage-related lysozyme 2691461 lys 8217283 lys Escherichia coli O157:H7 str. TW14359 phage-related lysozyme YP_003078590.1 2690964 R 544404 CDS YP_003078591.1 254793754 8217284 complement(2691461..2691676) 1 NC_013008.1 phage Lysis protein S 2691676 s 8217284 s Escherichia coli O157:H7 str. TW14359 phage Lysis protein S YP_003078591.1 2691461 R 544404 CDS YP_003078592.1 254793755 8217285 complement(2691753..2692025) 1 NC_013008.1 hypothetical protein 2692025 8217285 ECSP_2719 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078592.1 2691753 R 544404 CDS YP_003078593.1 254793756 8217286 complement(2692066..2692245) 1 NC_013008.1 hypothetical protein 2692245 8217286 ECSP_2720 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078593.1 2692066 R 544404 CDS YP_003078594.1 254793757 8217287 complement(2692382..2694319) 1 NC_013008.1 hypothetical protein 2694319 8217287 ECSP_2721 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078594.1 2692382 R 544404 CDS YP_003078595.1 254793758 8217288 complement(2695183..2695452) 1 NC_013008.1 Shiga-like toxin II subunit B 2695452 stx2cB 8217288 stx2cB Escherichia coli O157:H7 str. TW14359 Shiga-like toxin II subunit B YP_003078595.1 2695183 R 544404 CDS YP_003078596.1 254793759 8217289 complement(2695464..2696423) 1 NC_013008.1 Shiga-like toxin II subunit A 2696423 stx2A1 8217289 stx2A1 Escherichia coli O157:H7 str. TW14359 Shiga-like toxin II subunit A YP_003078596.1 2695464 R 544404 CDS YP_003078597.1 254793760 8217293 complement(2697073..2697561) 1 NC_013008.1 antitermination protein Q 2697561 8217293 ECSP_2727 Escherichia coli O157:H7 str. TW14359 antitermination protein Q YP_003078597.1 2697073 R 544404 CDS YP_003078598.1 254793761 8217294 complement(2697552..2698223) 1 NC_013008.1 serine/threonine protein phosphatase 1 2698223 8217294 ECSP_2728 Escherichia coli O157:H7 str. TW14359 serine/threonine protein phosphatase 1 YP_003078598.1 2697552 R 544404 CDS YP_003078599.1 254793762 8217295 complement(2698220..2698825) 1 NC_013008.1 protein ninG 2698825 8217295 ECSP_2729 Escherichia coli O157:H7 str. TW14359 protein ninG YP_003078599.1 2698220 R 544404 CDS YP_003078600.1 254793763 8217296 complement(2698825..2699547) 1 NC_013008.1 DNA-binding protein Roi 2699547 8217296 ECSP_2730 Escherichia coli O157:H7 str. TW14359 DNA-binding protein Roi YP_003078600.1 2698825 R 544404 CDS YP_003078601.1 254793764 8217297 complement(2699622..2700302) 1 NC_013008.1 antirepressor protein ant 2700302 8217297 ECSP_2731 Escherichia coli O157:H7 str. TW14359 antirepressor protein ant YP_003078601.1 2699622 R 544404 CDS YP_003078602.1 254793765 8217298 complement(2700558..2701316) 1 NC_013008.1 anti-termination protein 2701316 antA 8217298 antA Escherichia coli O157:H7 str. TW14359 anti-termination protein YP_003078602.1 2700558 R 544404 CDS YP_003078603.1 254793766 8217299 complement(2701770..2702297) 1 NC_013008.1 DNA methyltransferase 2702297 8217299 ECSP_2733 Escherichia coli O157:H7 str. TW14359 DNA methyltransferase YP_003078603.1 2701770 R 544404 CDS YP_003078604.1 254793767 8217300 complement(2702294..2702740) 1 NC_013008.1 recombination protein ninB 2702740 8217300 ECSP_2734 Escherichia coli O157:H7 str. TW14359 recombination protein ninB YP_003078604.1 2702294 R 544404 CDS YP_003078605.1 254793768 8217301 complement(2702697..2703059) 1 NC_013008.1 hypothetical protein 2703059 8217301 ECSP_2735 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078605.1 2702697 R 544404 CDS YP_003078606.1 254793769 8217302 complement(2703292..2703570) 1 NC_013008.1 hypothetical protein 2703570 8217302 ECSP_2736 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078606.1 2703292 R 544404 CDS YP_003078607.1 254793770 8217303 complement(2703641..2705017) 1 NC_013008.1 replicative DNA helicase 2705017 8217303 ECSP_2737 Escherichia coli O157:H7 str. TW14359 replicative DNA helicase YP_003078607.1 2703641 R 544404 CDS YP_003078608.1 254793771 8217304 complement(2705014..2705835) 1 NC_013008.1 bacteriophage replication protein O 2705835 8217304 ECSP_2738 Escherichia coli O157:H7 str. TW14359 bacteriophage replication protein O YP_003078608.1 2705014 R 544404 CDS YP_003078609.1 254793772 8217305 complement(2706016..2706312) 1 NC_013008.1 regulatory protein CII 2706312 8217305 ECSP_2739 Escherichia coli O157:H7 str. TW14359 regulatory protein CII YP_003078609.1 2706016 R 544404 CDS YP_003078610.1 254793773 8217306 complement(2706454..2706669) 1 NC_013008.1 Cro antirepressor 2706669 8217306 ECSP_2740 Escherichia coli O157:H7 str. TW14359 Cro antirepressor YP_003078610.1 2706454 R 544404 CDS YP_003078611.1 254793774 8217307 2706745..2707440 1 NC_013008.1 repressor protein CI 2707440 8217307 ECSP_2741 Escherichia coli O157:H7 str. TW14359 repressor protein CI YP_003078611.1 2706745 D 544404 CDS YP_003078612.1 254793775 8217308 2707942..2708463 1 NC_013008.1 hypothetical protein 2708463 8217308 ECSP_2742 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078612.1 2707942 D 544404 CDS YP_003078613.1 254793776 8217309 2709120..2709464 1 NC_013008.1 anti-termination protein N 2709464 antN 8217309 antN Escherichia coli O157:H7 str. TW14359 anti-termination protein N YP_003078613.1 2709120 D 544404 CDS YP_003078614.1 254793777 8217310 2709523..2709774 1 NC_013008.1 hypothetical protein 2709774 8217310 ECSP_2744 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078614.1 2709523 D 544404 CDS YP_003078615.1 254793778 8217311 2709957..2710325 1 NC_013008.1 single stranded binding protein 2710325 8217311 ECSP_2745 Escherichia coli O157:H7 str. TW14359 single stranded binding protein YP_003078615.1 2709957 D 544404 CDS YP_003078616.1 254793779 8217312 2710405..2710674 1 NC_013008.1 host killing protein Kil 2710674 kil1 8217312 kil1 Escherichia coli O157:H7 str. TW14359 host killing protein Kil YP_003078616.1 2710405 D 544404 CDS YP_003078617.1 254793780 8217313 2710629..2711045 1 NC_013008.1 host-nuclease inhibitor protein gam 2711045 8217313 ECSP_2747 Escherichia coli O157:H7 str. TW14359 host-nuclease inhibitor protein gam YP_003078617.1 2710629 D 544404 CDS YP_003078618.1 254793781 8217314 2711051..2711836 1 NC_013008.1 recombination protein bet 2711836 bet1 8217314 bet1 Escherichia coli O157:H7 str. TW14359 recombination protein bet YP_003078618.1 2711051 D 544404 CDS YP_003078619.1 254793782 8217315 complement(2712131..2713021) 1 NC_013008.1 transposase 2713021 8217315 ECSP_2749 Escherichia coli O157:H7 str. TW14359 transposase YP_003078619.1 2712131 R 544404 CDS YP_003078620.1 254793783 8217316 complement(2713018..2713344) 1 NC_013008.1 transposase 2713344 8217316 ECSP_2750 Escherichia coli O157:H7 str. TW14359 transposase YP_003078620.1 2713018 R 544404 CDS YP_003078621.1 254793784 8217318 2713817..2714005 1 NC_013008.1 hypothetical protein 2714005 8217318 ECSP_2752 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078621.1 2713817 D 544404 CDS YP_003078622.1 254793785 8217319 2713978..2714169 1 NC_013008.1 hypothetical protein 2714169 8217319 ECSP_2753 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078622.1 2713978 D 544404 CDS YP_003078623.1 254793786 8217320 2714180..2714461 1 NC_013008.1 hypothetical protein 2714461 8217320 ECSP_2754 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078623.1 2714180 D 544404 CDS YP_003078624.1 254793787 8217321 2714560..2714781 1 NC_013008.1 DnaK suppressor protein 2714781 8217321 ECSP_2755 Escherichia coli O157:H7 str. TW14359 DnaK suppressor protein YP_003078624.1 2714560 D 544404 CDS YP_003078625.1 254793788 8217322 2714778..2715725 1 NC_013008.1 hypothetical protein 2715725 8217322 ECSP_2756 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078625.1 2714778 D 544404 CDS YP_003078626.1 254793789 8217324 2716237..2716593 1 NC_013008.1 hypothetical protein 2716593 8217324 ECSP_2758 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078626.1 2716237 D 544404 CDS YP_003078627.1 254793790 8217325 2716590..2716940 1 NC_013008.1 hypothetical protein 2716940 8217325 ECSP_2759 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078627.1 2716590 D 544404 CDS YP_003078628.1 254793791 8217326 2717128..2717472 1 NC_013008.1 hypothetical protein 2717472 8217326 ECSP_2760 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078628.1 2717128 D 544404 CDS YP_003078629.1 254793792 8217327 complement(2717722..2718900) 1 NC_013008.1 prophage integrase 2718900 int 8217327 int Escherichia coli O157:H7 str. TW14359 prophage integrase YP_003078629.1 2717722 R 544404 CDS YP_003078630.1 254793793 8217328 2719082..2720506 1 NC_013008.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2720506 sbcB 8217328 sbcB Escherichia coli O157:H7 str. TW14359 exonuclease I YP_003078630.1 2719082 D 544404 CDS YP_003078631.1 254793794 8217329 complement(2720549..2720776) 1 NC_013008.1 hypothetical protein 2720776 yeeD 8217329 yeeD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078631.1 2720549 R 544404 CDS YP_003078632.1 254793795 8217330 complement(2720790..2721848) 1 NC_013008.1 inner membrane protein 2721848 yeeE 8217330 yeeE Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078632.1 2720790 R 544404 CDS YP_003078633.1 254793796 8217331 complement(2722027..2723385) 1 NC_013008.1 amino-acid transporter 2723385 yeeF 8217331 yeeF Escherichia coli O157:H7 str. TW14359 amino-acid transporter YP_003078633.1 2722027 R 544404 CDS YP_003078634.1 254793797 8217332 complement(2723652..2724581) 1 NC_013008.1 DNA-binding transcriptional regulator 2724581 yeeY 8217332 yeeY Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078634.1 2723652 R 544404 CDS YP_003078635.1 254793798 8217333 complement(2724627..2725451) 1 NC_013008.1 epimerase, with NAD(P)-binding Rossmann-fold domain 2725451 yeeZ 8217333 yeeZ Escherichia coli O157:H7 str. TW14359 epimerase, with NAD(P)-binding Rossmann-fold domain YP_003078635.1 2724627 R 544404 CDS YP_003078636.1 254793799 8217334 2725524..2725730 1 NC_013008.1 hypothetical protein 2725730 8217334 ECSP_2768 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078636.1 2725524 D 544404 CDS YP_003078638.1 254793801 8217336 2726073..2726972 1 NC_013008.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2726972 hisG 8217336 hisG Escherichia coli O157:H7 str. TW14359 ATP phosphoribosyltransferase YP_003078638.1 2726073 D 544404 CDS YP_003078639.1 254793802 8217337 2726978..2728282 1 NC_013008.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2728282 hisD 8217337 hisD Escherichia coli O157:H7 str. TW14359 histidinol dehydrogenase YP_003078639.1 2726978 D 544404 CDS YP_003078640.1 254793803 8217338 2728279..2729349 1 NC_013008.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2729349 hisC 8217338 hisC Escherichia coli O157:H7 str. TW14359 histidinol-phosphate aminotransferase YP_003078640.1 2728279 D 544404 CDS YP_003078641.1 254793804 8217339 2729349..2730416 1 NC_013008.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2730416 hisB 8217339 hisB Escherichia coli O157:H7 str. TW14359 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_003078641.1 2729349 D 544404 CDS YP_003078642.1 254793805 8217340 2730416..2731006 1 NC_013008.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2731006 hisH 8217340 hisH Escherichia coli O157:H7 str. TW14359 imidazole glycerol phosphate synthase subunit HisH YP_003078642.1 2730416 D 544404 CDS YP_003078643.1 254793806 8217341 2731006..2731743 1 NC_013008.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2731743 hisA 8217341 hisA Escherichia coli O157:H7 str. TW14359 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_003078643.1 2731006 D 544404 CDS YP_003078644.1 254793807 8217342 2731725..2732501 1 NC_013008.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2732501 hisF 8217342 hisF Escherichia coli O157:H7 str. TW14359 imidazole glycerol phosphate synthase subunit HisF YP_003078644.1 2731725 D 544404 CDS YP_003078645.1 254793808 8217343 2732495..2733106 1 NC_013008.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 2733106 hisI 8217343 hisI Escherichia coli O157:H7 str. TW14359 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_003078645.1 2732495 D 544404 CDS YP_003078646.1 254793809 8217344 complement(2733203..2734180) 1 NC_013008.1 regulator of length of O-antigen component of lipopolysaccharide chains 2734180 cld 8217344 cld Escherichia coli O157:H7 str. TW14359 regulator of length of O-antigen component of lipopolysaccharide chains YP_003078646.1 2733203 R 544404 CDS YP_003078647.1 254793810 8217345 complement(2734326..2735492) 1 NC_013008.1 UDP-glucose 6-dehydrogenase 2735492 ugd 8217345 ugd Escherichia coli O157:H7 str. TW14359 UDP-glucose 6-dehydrogenase YP_003078647.1 2734326 R 544404 CDS YP_003078648.1 254793811 8217346 complement(2735741..2737147) 1 NC_013008.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2737147 gnd 8217346 gnd Escherichia coli O157:H7 str. TW14359 6-phosphogluconate dehydrogenase YP_003078648.1 2735741 R 544404 CDS YP_003078649.1 254793812 8217347 complement(2737348..2738013) 1 NC_013008.1 acetyl transferase; O-antigen biosynthesis 2738013 wbdR 8217347 wbdR Escherichia coli O157:H7 str. TW14359 acetyl transferase; O-antigen biosynthesis YP_003078649.1 2737348 R 544404 CDS YP_003078650.1 254793813 8217350 complement(2738707..2738817) 1 NC_013008.1 H repeat-associated protein 2738817 8217350 ECSP_2784 Escherichia coli O157:H7 str. TW14359 H repeat-associated protein YP_003078650.1 2738707 R 544404 CDS YP_003078651.1 254793814 8217351 complement(2739276..2740646) 1 NC_013008.1 phosphomannomutase 2740646 manB 8217351 manB Escherichia coli O157:H7 str. TW14359 phosphomannomutase YP_003078651.1 2739276 R 544404 CDS YP_003078652.1 254793815 8217352 complement(2740650..2742098) 1 NC_013008.1 mannose-1-phosphate guanylyltransferase 2742098 manC 8217352 manC Escherichia coli O157:H7 str. TW14359 mannose-1-phosphate guanylyltransferase YP_003078652.1 2740650 R 544404 CDS YP_003078653.1 254793816 8217353 complement(2742080..2742589) 1 NC_013008.1 GDP-mannose mannosylhydrolase 2742589 wbdQ 8217353 wbdQ Escherichia coli O157:H7 str. TW14359 GDP-mannose mannosylhydrolase YP_003078653.1 2742080 R 544404 CDS YP_003078654.1 254793817 8217354 complement(2742592..2743557) 1 NC_013008.1 fucose synthetase 2743557 8217354 ECSP_2788 Escherichia coli O157:H7 str. TW14359 fucose synthetase YP_003078654.1 2742592 R 544404 CDS YP_003078655.1 254793818 8217355 complement(2743560..2744678) 1 NC_013008.1 GDP-mannose dehydratase 2744678 gmd1 8217355 gmd1 Escherichia coli O157:H7 str. TW14359 GDP-mannose dehydratase YP_003078655.1 2743560 R 544404 CDS YP_003078656.1 254793819 8217356 complement(2744698..2745912) 1 NC_013008.1 glycosyl transferase 2745912 wbdP 8217356 wbdP Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078656.1 2744698 R 544404 CDS YP_003078657.1 254793820 8217357 complement(2745937..2747031) 1 NC_013008.1 perosamine synthetase 2747031 per 8217357 per Escherichia coli O157:H7 str. TW14359 perosamine synthetase YP_003078657.1 2745937 R 544404 CDS YP_003078658.1 254793821 8217358 complement(2747034..2748425) 1 NC_013008.1 O antigen flippase 2748425 wzx 8217358 wzx Escherichia coli O157:H7 str. TW14359 O antigen flippase YP_003078658.1 2747034 R 544404 CDS YP_003078659.1 254793822 8217359 complement(2748412..2749158) 1 NC_013008.1 glycosyl transferase 2749158 wbdO 8217359 wbdO Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078659.1 2748412 R 544404 CDS YP_003078660.1 254793823 8217360 complement(2749127..2750311) 1 NC_013008.1 O antigen polymerase 2750311 wzy 8217360 wzy Escherichia coli O157:H7 str. TW14359 O antigen polymerase YP_003078660.1 2749127 R 544404 CDS YP_003078661.1 254793824 8217361 complement(2750308..2751090) 1 NC_013008.1 glycosyl transferase 2751090 wbdN 8217361 wbdN Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078661.1 2750308 R 544404 CDS YP_003078662.1 254793825 8217362 complement(2751409..2752302) 1 NC_013008.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 2752302 galF 8217362 galF Escherichia coli O157:H7 str. TW14359 UTP-glucose-1-phosphate uridylyltransferase YP_003078662.1 2751409 R 544404 CDS YP_003078663.1 254793826 8217363 complement(2752545..2753540) 1 NC_013008.1 UDP-N-acetylglucosamine 4-epimerase 2753540 gne 8217363 gne Escherichia coli O157:H7 str. TW14359 UDP-N-acetylglucosamine 4-epimerase YP_003078663.1 2752545 R 544404 CDS YP_003078664.1 254793827 8217364 complement(2753698..2755092) 1 NC_013008.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2755092 wcaM 8217364 wcaM Escherichia coli O157:H7 str. TW14359 colanic acid biosynthesis protein YP_003078664.1 2753698 R 544404 CDS YP_003078665.1 254793828 8217365 complement(2755103..2756323) 1 NC_013008.1 glycosyl transferase 2756323 wcaL 8217365 wcaL Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078665.1 2755103 R 544404 CDS YP_003078666.1 254793829 8217366 complement(2756320..2757600) 1 NC_013008.1 pyruvyl transferase 2757600 wcaK 8217366 wcaK Escherichia coli O157:H7 str. TW14359 pyruvyl transferase YP_003078666.1 2756320 R 544404 CDS YP_003078667.1 254793830 8217367 complement(2757780..2759258) 1 NC_013008.1 colanic acid exporter 2759258 wzxC 8217367 wzxC Escherichia coli O157:H7 str. TW14359 colanic acid exporter YP_003078667.1 2757780 R 544404 CDS YP_003078668.1 254793831 8217368 complement(2759260..2760654) 1 NC_013008.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2760654 wcaJ 8217368 wcaJ Escherichia coli O157:H7 str. TW14359 UDP-glucose lipid carrier transferase YP_003078668.1 2759260 R 544404 CDS YP_003078669.1 254793832 8217369 complement(2760709..2762079) 1 NC_013008.1 phosphomannomutase 2762079 cpsG 8217369 cpsG Escherichia coli O157:H7 str. TW14359 phosphomannomutase YP_003078669.1 2760709 R 544404 CDS YP_003078670.1 254793833 8217370 complement(2762272..2763708) 1 NC_013008.1 mannose-1-phosphate guanylyltransferase 2763708 cpsB 8217370 cpsB Escherichia coli O157:H7 str. TW14359 mannose-1-phosphate guanylyltransferase YP_003078670.1 2762272 R 544404 CDS YP_003078671.1 254793834 8217371 complement(2763711..2764934) 1 NC_013008.1 glycosyl transferase 2764934 wcaI 8217371 wcaI Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078671.1 2763711 R 544404 CDS YP_003078672.1 254793835 8217372 complement(2764931..2765410) 1 NC_013008.1 GDP-mannose mannosyl hydrolase 2765410 gmm 8217372 gmm Escherichia coli O157:H7 str. TW14359 GDP-mannose mannosyl hydrolase YP_003078672.1 2764931 R 544404 CDS YP_003078673.1 254793836 8217373 complement(2765413..2766378) 1 NC_013008.1 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase 2766378 8217373 ECSP_2807 Escherichia coli O157:H7 str. TW14359 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase YP_003078673.1 2765413 R 544404 CDS YP_003078674.1 254793837 8217374 complement(2766381..2767502) 1 NC_013008.1 GDP-D-mannose dehydratase, NAD(P)-binding 2767502 gmd2 8217374 gmd2 Escherichia coli O157:H7 str. TW14359 GDP-D-mannose dehydratase, NAD(P)-binding YP_003078674.1 2766381 R 544404 CDS YP_003078675.1 254793838 8217375 complement(2767531..2768079) 1 NC_013008.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2768079 wcaF 8217375 wcaF Escherichia coli O157:H7 str. TW14359 colanic acid biosynthesis acetyltransferase WcaF YP_003078675.1 2767531 R 544404 CDS YP_003078676.1 254793839 8217376 complement(2768095..2768841) 1 NC_013008.1 glycosyl transferase 2768841 wcaE 8217376 wcaE Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078676.1 2768095 R 544404 CDS YP_003078677.1 254793840 8217377 complement(2768852..2770069) 1 NC_013008.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2770069 wcaD 8217377 wcaD Escherichia coli O157:H7 str. TW14359 colanic acid biosynthesis protein YP_003078677.1 2768852 R 544404 CDS YP_003078678.1 254793841 8217378 complement(2770044..2771261) 1 NC_013008.1 glycosyl transferase 2771261 wcaC 8217378 wcaC Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078678.1 2770044 R 544404 CDS YP_003078679.1 254793842 8217379 complement(2771258..2771746) 1 NC_013008.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2771746 wcaB 8217379 wcaB Escherichia coli O157:H7 str. TW14359 colanic acid biosynthesis acetyltransferase WcaB YP_003078679.1 2771258 R 544404 CDS YP_003078680.1 254793843 8217380 complement(2771749..2772588) 1 NC_013008.1 glycosyl transferase 2772588 wcaA 8217380 wcaA Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003078680.1 2771749 R 544404 CDS YP_003078681.1 254793844 8217381 complement(2772681..2774843) 1 NC_013008.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2774843 wzc 8217381 wzc Escherichia coli O157:H7 str. TW14359 tyrosine kinase YP_003078681.1 2772681 R 544404 CDS YP_003078682.1 254793845 8217382 complement(2774846..2775289) 1 NC_013008.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2775289 wzb 8217382 wzb Escherichia coli O157:H7 str. TW14359 tyrosine phosphatase YP_003078682.1 2774846 R 544404 CDS YP_003078683.1 254793846 8217383 complement(2775295..2776434) 1 NC_013008.1 capsular polysaccharide translocation lipoprotein 2776434 wza 8217383 wza Escherichia coli O157:H7 str. TW14359 capsular polysaccharide translocation lipoprotein YP_003078683.1 2775295 R 544404 CDS YP_003078684.1 254793847 8217384 2777093..2778676 1 NC_013008.1 fused membrane protein, membrane protein 2778676 yegH 8217384 yegH Escherichia coli O157:H7 str. TW14359 fused membrane protein, membrane protein YP_003078684.1 2777093 D 544404 CDS YP_003078685.1 254793848 8217385 2778751..2779089 1 NC_013008.1 hypothetical protein 2779089 8217385 ECSP_2819 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078685.1 2778751 D 544404 CDS YP_003078686.1 254793849 8217386 2779079..2779369 1 NC_013008.1 hypothetical protein 2779369 8217386 ECSP_2820 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078686.1 2779079 D 544404 CDS YP_003078687.1 254793850 8217387 complement(2779422..2781275) 1 NC_013008.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2781275 asmA 8217387 asmA Escherichia coli O157:H7 str. TW14359 assembly protein YP_003078687.1 2779422 R 544404 CDS YP_003078688.1 254793851 8217388 complement(2781297..2781878) 1 NC_013008.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2781878 dcd 8217388 dcd Escherichia coli O157:H7 str. TW14359 deoxycytidine triphosphate deaminase YP_003078688.1 2781297 R 544404 CDS YP_003078689.1 254793852 8217389 complement(2781970..2782611) 1 NC_013008.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2782611 udk 8217389 udk Escherichia coli O157:H7 str. TW14359 uridine kinase YP_003078689.1 2781970 R 544404 CDS YP_003078690.1 254793853 8217391 complement(2786348..2787196) 1 NC_013008.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase 2787196 alkA 8217391 alkA Escherichia coli O157:H7 str. TW14359 3-methyl-adenine DNA glycosylase YP_003078690.1 2786348 R 544404 CDS YP_003078691.1 254793854 8217392 2787329..2788681 1 NC_013008.1 chaperone 2788681 yegD 8217392 yegD Escherichia coli O157:H7 str. TW14359 chaperone YP_003078691.1 2787329 D 544404 CDS YP_003078692.1 254793855 8217393 complement(2788694..2790634) 1 NC_013008.1 hypothetical protein 2790634 yegI 8217393 yegI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078692.1 2788694 R 544404 CDS YP_003078693.1 254793856 8217394 complement(2790631..2791392) 1 NC_013008.1 hypothetical protein 2791392 yegK 8217394 yegK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078693.1 2790631 R 544404 CDS YP_003078694.1 254793857 8217395 complement(2791389..2792048) 1 NC_013008.1 hypothetical protein 2792048 yegL 8217395 yegL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078694.1 2791389 R 544404 CDS YP_003078695.1 254793858 8217396 2792619..2792765 1 NC_013008.1 hypothetical protein 2792765 8217396 ECSP_2830 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078695.1 2792619 D 544404 CDS YP_003078696.1 254793859 8217397 2793264..2794511 1 NC_013008.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2794511 mdtA 8217397 mdtA Escherichia coli O157:H7 str. TW14359 multidrug efflux system subunit MdtA YP_003078696.1 2793264 D 544404 CDS YP_003078697.1 254793860 8217398 2794511..2797633 1 NC_013008.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2797633 mdtB 8217398 mdtB Escherichia coli O157:H7 str. TW14359 multidrug efflux system subunit MdtB YP_003078697.1 2794511 D 544404 CDS YP_003078698.1 254793861 8217399 2797634..2800711 1 NC_013008.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2800711 mdtC 8217399 mdtC Escherichia coli O157:H7 str. TW14359 multidrug efflux system subunit MdtC YP_003078698.1 2797634 D 544404 CDS YP_003078699.1 254793862 8217400 2800712..2802127 1 NC_013008.1 multidrug efflux system protein MdtE 2802127 mdtD 8217400 mdtD Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein MdtE YP_003078699.1 2800712 D 544404 CDS YP_003078700.1 254793863 8217401 2802124..2803527 1 NC_013008.1 signal transduction histidine-protein kinase BaeS 2803527 baeS 8217401 baeS Escherichia coli O157:H7 str. TW14359 signal transduction histidine-protein kinase BaeS YP_003078700.1 2802124 D 544404 CDS YP_003078701.1 254793864 8217402 2803524..2804246 1 NC_013008.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2804246 baeR 8217402 baeR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator BaeR YP_003078701.1 2803524 D 544404 CDS YP_003078702.1 254793865 8217403 2804437..2804769 1 NC_013008.1 hypothetical protein 2804769 yegP 8217403 yegP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078702.1 2804437 D 544404 CDS YP_003078703.1 254793866 8217404 2804917..2806278 1 NC_013008.1 peptidase 2806278 yegQ 8217404 yegQ Escherichia coli O157:H7 str. TW14359 peptidase YP_003078703.1 2804917 D 544404 CDS YP_003078704.1 254793867 8217405 complement(2806552..2806806) 1 NC_013008.1 in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 2806806 8217405 ECSP_2839 Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078704.1 2806552 R 544404 CDS YP_003078705.1 254793868 8217406 complement(2806852..2808015) 1 NC_013008.1 phage protein D 2808015 8217406 ECSP_2840 Escherichia coli O157:H7 str. TW14359 phage protein D YP_003078705.1 2806852 R 544404 CDS YP_003078706.1 254793869 8217407 complement(2808015..2808494) 1 NC_013008.1 phage protein gpU 2808494 8217407 ECSP_2841 Escherichia coli O157:H7 str. TW14359 phage protein gpU YP_003078706.1 2808015 R 544404 CDS YP_003078707.1 254793870 8217408 complement(2808509..2810956) 1 NC_013008.1 phage related tail protein 2810956 8217408 ECSP_2842 Escherichia coli O157:H7 str. TW14359 phage related tail protein YP_003078707.1 2808509 R 544404 CDS YP_003078708.1 254793871 8217409 complement(2811101..2811376) 1 NC_013008.1 hypothetical protein 2811376 8217409 ECSP_2843 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078708.1 2811101 R 544404 CDS YP_003078709.1 254793872 8217410 complement(2811433..2811951) 1 NC_013008.1 phage tail tube protein FII 2811951 8217410 ECSP_2844 Escherichia coli O157:H7 str. TW14359 phage tail tube protein FII YP_003078709.1 2811433 R 544404 CDS YP_003078710.1 254793873 8217411 complement(2811964..2813154) 1 NC_013008.1 phage tail sheath protein FI 2813154 8217411 ECSP_2845 Escherichia coli O157:H7 str. TW14359 phage tail sheath protein FI YP_003078710.1 2811964 R 544404 CDS YP_003078711.1 254793874 8217412 complement(2813214..2813807) 1 NC_013008.1 DNA-invertase 2813807 8217412 ECSP_2846 Escherichia coli O157:H7 str. TW14359 DNA-invertase YP_003078711.1 2813214 R 544404 CDS YP_003078712.1 254793875 8217413 2813838..2814248 1 NC_013008.1 tail fiber protein 2814248 8217413 ECSP_2847 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003078712.1 2813838 D 544404 CDS YP_003078713.1 254793876 8217414 2814269..2814712 1 NC_013008.1 tail fiber assembly protein 2814712 8217414 ECSP_2848 Escherichia coli O157:H7 str. TW14359 tail fiber assembly protein YP_003078713.1 2814269 D 544404 CDS YP_003078714.1 254793877 8217415 complement(2814684..2815286) 1 NC_013008.1 tail fiber assembly protein 2815286 8217415 ECSP_2849 Escherichia coli O157:H7 str. TW14359 tail fiber assembly protein YP_003078714.1 2814684 R 544404 CDS YP_003078715.1 254793878 8217416 complement(2815286..2816605) 1 NC_013008.1 phage tail fiber protein 2816605 8217416 ECSP_2850 Escherichia coli O157:H7 str. TW14359 phage tail fiber protein YP_003078715.1 2815286 R 544404 CDS YP_003078716.1 254793879 8217417 complement(2816602..2817213) 1 NC_013008.1 phage P2-related tail formation protein 2817213 8217417 ECSP_2851 Escherichia coli O157:H7 str. TW14359 phage P2-related tail formation protein YP_003078716.1 2816602 R 544404 CDS YP_003078717.1 254793880 8217418 complement(2817206..2818114) 1 NC_013008.1 baseplate assembly protein 2818114 8217418 ECSP_2852 Escherichia coli O157:H7 str. TW14359 baseplate assembly protein YP_003078717.1 2817206 R 544404 CDS YP_003078718.1 254793881 8217419 complement(2818119..2818466) 1 NC_013008.1 phage baseplate protein 2818466 8217419 ECSP_2853 Escherichia coli O157:H7 str. TW14359 phage baseplate protein YP_003078718.1 2818119 R 544404 CDS YP_003078719.1 254793882 8217420 complement(2818463..2819098) 1 NC_013008.1 phage baseplate protein 2819098 8217420 ECSP_2854 Escherichia coli O157:H7 str. TW14359 phage baseplate protein YP_003078719.1 2818463 R 544404 CDS YP_003078720.1 254793883 8217421 complement(2819165..2819617) 1 NC_013008.1 phage tail protein 2819617 8217421 ECSP_2855 Escherichia coli O157:H7 str. TW14359 phage tail protein YP_003078720.1 2819165 R 544404 CDS YP_003078721.1 254793884 8217422 complement(2819610..2820077) 1 NC_013008.1 P2 phage tail completion protein R, GpR 2820077 8217422 ECSP_2856 Escherichia coli O157:H7 str. TW14359 P2 phage tail completion protein R, GpR YP_003078721.1 2819610 R 544404 CDS YP_003078722.1 254793885 8217423 complement(2820040..2820198) 1 NC_013008.1 phage lysis protein LysC 2820198 8217423 ECSP_2857 Escherichia coli O157:H7 str. TW14359 phage lysis protein LysC YP_003078722.1 2820040 R 544404 CDS YP_003078723.1 254793886 8217424 complement(2820185..2820610) 1 NC_013008.1 phage lysis timing protein LysB 2820610 8217424 ECSP_2858 Escherichia coli O157:H7 str. TW14359 phage lysis timing protein LysB YP_003078723.1 2820185 R 544404 CDS YP_003078724.1 254793887 8217425 complement(2820598..2821023) 1 NC_013008.1 phage lysis protein LysA 2821023 8217425 ECSP_2859 Escherichia coli O157:H7 str. TW14359 phage lysis protein LysA YP_003078724.1 2820598 R 544404 CDS YP_003078725.1 254793888 8217426 complement(2821038..2821535) 1 NC_013008.1 phage lysozyme 2821535 8217426 ECSP_2860 Escherichia coli O157:H7 str. TW14359 phage lysozyme YP_003078725.1 2821038 R 544404 CDS YP_003078726.1 254793889 8217427 complement(2821535..2821816) 1 NC_013008.1 hypothetical protein 2821816 8217427 ECSP_2861 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078726.1 2821535 R 544404 CDS YP_003078727.1 254793890 8217428 complement(2821820..2822023) 1 NC_013008.1 P2-like prophage tail protein X 2822023 8217428 ECSP_2862 Escherichia coli O157:H7 str. TW14359 P2-like prophage tail protein X YP_003078727.1 2821820 R 544404 CDS YP_003078728.1 254793891 8217429 complement(2822023..2822496) 1 NC_013008.1 capsid completion protein 2822496 8217429 ECSP_2863 Escherichia coli O157:H7 str. TW14359 capsid completion protein YP_003078728.1 2822023 R 544404 CDS YP_003078729.1 254793892 8217430 complement(2822632..2823375) 1 NC_013008.1 small terminase subunit 2823375 8217430 ECSP_2864 Escherichia coli O157:H7 str. TW14359 small terminase subunit YP_003078729.1 2822632 R 544404 CDS YP_003078730.1 254793893 8217431 complement(2823379..2824452) 1 NC_013008.1 phage major capsid protein, P2 family 2824452 8217431 ECSP_2865 Escherichia coli O157:H7 str. TW14359 phage major capsid protein, P2 family YP_003078730.1 2823379 R 544404 CDS YP_003078731.1 254793894 8217432 complement(2824511..2825365) 1 NC_013008.1 phage capsid scaffolding protein GpO 2825365 8217432 ECSP_2866 Escherichia coli O157:H7 str. TW14359 phage capsid scaffolding protein GpO YP_003078731.1 2824511 R 544404 CDS YP_003078732.1 254793895 8217433 2825539..2827311 1 NC_013008.1 phage large terminase subunit GpP 2827311 8217433 ECSP_2867 Escherichia coli O157:H7 str. TW14359 phage large terminase subunit GpP YP_003078732.1 2825539 D 544404 CDS YP_003078733.1 254793896 8217434 2827311..2828345 1 NC_013008.1 phage capsid protein 2828345 8217434 ECSP_2868 Escherichia coli O157:H7 str. TW14359 phage capsid protein YP_003078733.1 2827311 D 544404 CDS YP_003078734.1 254793897 8217435 complement(2828384..2828545) 1 NC_013008.1 hypothetical protein 2828545 8217435 ECSP_2869 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078734.1 2828384 R 544404 CDS YP_003078735.1 254793898 8217436 complement(2828663..2830630) 1 NC_013008.1 virulence factor 2830630 8217436 ECSP_2870 Escherichia coli O157:H7 str. TW14359 virulence factor YP_003078735.1 2828663 R 544404 CDS YP_003078736.1 254793899 8217437 complement(2830630..2831142) 1 NC_013008.1 hypothetical protein 2831142 8217437 ECSP_2871 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078736.1 2830630 R 544404 CDS YP_003078737.1 254793900 8217438 complement(2831129..2832352) 1 NC_013008.1 virulence factor 2832352 8217438 ECSP_2872 Escherichia coli O157:H7 str. TW14359 virulence factor YP_003078737.1 2831129 R 544404 CDS YP_003078738.1 254793901 8217439 complement(2832442..2834724) 1 NC_013008.1 phage replication initiation protein 2834724 8217439 ECSP_2873 Escherichia coli O157:H7 str. TW14359 phage replication initiation protein YP_003078738.1 2832442 R 544404 CDS YP_003078739.1 254793902 8217440 complement(2834714..2834989) 1 NC_013008.1 hypothetical protein 2834989 8217440 ECSP_2874 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078739.1 2834714 R 544404 CDS YP_003078740.1 254793903 8217441 complement(2834986..2835210) 1 NC_013008.1 hypothetical protein 2835210 8217441 ECSP_2875 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078740.1 2834986 R 544404 CDS YP_003078741.1 254793904 8217442 complement(2835213..2835512) 1 NC_013008.1 hypothetical protein 2835512 8217442 ECSP_2876 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078741.1 2835213 R 544404 CDS YP_003078742.1 254793905 8217443 complement(2835512..2835736) 1 NC_013008.1 hypothetical protein 2835736 8217443 ECSP_2877 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078742.1 2835512 R 544404 CDS YP_003078743.1 254793906 8217444 complement(2835800..2836300) 1 NC_013008.1 replication gene B protein 2836300 8217444 ECSP_2878 Escherichia coli O157:H7 str. TW14359 replication gene B protein YP_003078743.1 2835800 R 544404 CDS YP_003078744.1 254793907 8217445 complement(2836297..2836467) 1 NC_013008.1 hypothetical protein 2836467 8217445 ECSP_2879 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078744.1 2836297 R 544404 CDS YP_003078745.1 254793908 8217446 complement(2836478..2836663) 1 NC_013008.1 hypothetical protein 2836663 8217446 ECSP_2880 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078745.1 2836478 R 544404 CDS YP_003078746.1 254793909 8217447 2836803..2837174 1 NC_013008.1 immunity repressor 2837174 8217447 ECSP_2881 Escherichia coli O157:H7 str. TW14359 immunity repressor YP_003078746.1 2836803 D 544404 CDS YP_003078747.1 254793910 8217448 2837290..2838303 1 NC_013008.1 integrase 2838303 8217448 ECSP_2882 Escherichia coli O157:H7 str. TW14359 integrase YP_003078747.1 2837290 D 544404 CDS YP_003078748.1 254793911 8217449 complement(2838568..2838885) 1 NC_013008.1 hypothetical protein 2838885 yegR 8217449 yegR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078748.1 2838568 R 544404 CDS YP_003078749.1 254793912 8217450 2839291..2840190 1 NC_013008.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2840190 yegS 8217450 yegS Escherichia coli O157:H7 str. TW14359 lipid kinase YP_003078749.1 2839291 D 544404 CDS YP_003078750.1 254793913 8217451 complement(2840272..2841051) 1 NC_013008.1 galactitol utilization operon repressor 2841051 gatR 8217451 gatR Escherichia coli O157:H7 str. TW14359 galactitol utilization operon repressor YP_003078750.1 2840272 R 544404 CDS YP_003078751.1 254793914 8217452 complement(2841151..2842191) 1 NC_013008.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2842191 gatD 8217452 gatD Escherichia coli O157:H7 str. TW14359 galactitol-1-phosphate dehydrogenase YP_003078751.1 2841151 R 544404 CDS YP_003078752.1 254793915 8217453 complement(2842239..2843594) 1 NC_013008.1 galactitol-specific enzyme IIC component of PTS 2843594 gatC 8217453 gatC Escherichia coli O157:H7 str. TW14359 galactitol-specific enzyme IIC component of PTS YP_003078752.1 2842239 R 544404 CDS YP_003078753.1 254793916 8217454 complement(2843598..2843882) 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2843882 gatB 8217454 gatB Escherichia coli O157:H7 str. TW14359 PTS system galactitol-specific transporter subunit IIB YP_003078753.1 2843598 R 544404 CDS YP_003078754.1 254793917 8217455 complement(2843913..2844365) 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2844365 gatA 8217455 gatA Escherichia coli O157:H7 str. TW14359 PTS system galactitol-specific transporter subunit IIA YP_003078754.1 2843913 R 544404 CDS YP_003078755.1 254793918 8217456 complement(2844375..2845637) 1 NC_013008.1 D-tagatose 1,6-bisphosphate aldolase 2 subunit 2845637 gatZ 8217456 gatZ Escherichia coli O157:H7 str. TW14359 D-tagatose 1,6-bisphosphate aldolase 2 subunit YP_003078755.1 2844375 R 544404 CDS YP_003078756.1 254793919 8217457 complement(2845666..2846520) 1 NC_013008.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2846520 gatY 8217457 gatY Escherichia coli O157:H7 str. TW14359 tagatose-bisphosphate aldolase YP_003078756.1 2845666 R 544404 CDS YP_003078757.1 254793920 8217458 complement(2846819..2847871) 1 NC_013008.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2847871 fbaB 8217458 fbaB Escherichia coli O157:H7 str. TW14359 fructose-bisphosphate aldolase YP_003078757.1 2846819 R 544404 CDS YP_003078758.1 254793921 8217459 2848128..2849405 1 NC_013008.1 nucleoside transporter 2849405 yegT 8217459 yegT Escherichia coli O157:H7 str. TW14359 nucleoside transporter YP_003078758.1 2848128 D 544404 CDS YP_003078759.1 254793922 8217460 2849402..2850406 1 NC_013008.1 hydrolase 2850406 yegU 8217460 yegU Escherichia coli O157:H7 str. TW14359 hydrolase YP_003078759.1 2849402 D 544404 CDS YP_003078760.1 254793923 8217461 2850403..2851368 1 NC_013008.1 kinase 2851368 yegV 8217461 yegV Escherichia coli O157:H7 str. TW14359 kinase YP_003078760.1 2850403 D 544404 CDS YP_003078761.1 254793924 8217462 complement(2851342..2852088) 1 NC_013008.1 DNA-binding transcriptional regulator 2852088 yegW 8217462 yegW Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078761.1 2851342 R 544404 CDS YP_003078762.1 254793925 8217463 complement(2852140..2852958) 1 NC_013008.1 hydrolase 2852958 yegX 8217463 yegX Escherichia coli O157:H7 str. TW14359 hydrolase YP_003078762.1 2852140 R 544404 CDS YP_003078763.1 254793926 8217464 complement(2853023..2853823) 1 NC_013008.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2853823 thiD 8217464 thiD Escherichia coli O157:H7 str. TW14359 phosphomethylpyrimidine kinase YP_003078763.1 2853023 R 544404 CDS YP_003078764.1 254793927 8217465 complement(2853820..2854608) 1 NC_013008.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2854608 thiM 8217465 thiM Escherichia coli O157:H7 str. TW14359 hydroxyethylthiazole kinase YP_003078764.1 2853820 R 544404 CDS YP_003078765.1 254793928 8217466 2854942..2855181 1 NC_013008.1 hypothetical protein 2855181 8217466 ECSP_2900 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078765.1 2854942 D 544404 CDS YP_003078766.1 254793929 8217467 complement(2855745..2855864) 1 NC_013008.1 hypothetical protein 2855864 8217467 ECSP_2901 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078766.1 2855745 R 544404 CDS YP_003078767.1 254793930 8217468 2856232..2856579 1 NC_013008.1 hypothetical protein 2856579 8217468 ECSP_2902 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078767.1 2856232 D 544404 CDS YP_003078768.1 254793931 8217469 2856589..2856903 1 NC_013008.1 hypothetical protein 2856903 8217469 ECSP_2903 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078768.1 2856589 D 544404 CDS YP_003078769.1 254793932 8217470 complement(2857013..2857285) 1 NC_013008.1 transcriptional repressor of rcnA 2857285 rcnR 8217470 rcnR Escherichia coli O157:H7 str. TW14359 transcriptional repressor of rcnA YP_003078769.1 2857013 R 544404 CDS YP_003078770.1 254793933 8217471 2857406..2858263 1 NC_013008.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2858263 yohM 8217471 yohM Escherichia coli O157:H7 str. TW14359 nickel/cobalt efflux protein RcnA YP_003078770.1 2857406 D 544404 CDS YP_003078771.1 254793934 8217472 2858481..2858819 1 NC_013008.1 hypothetical protein 2858819 yohN 8217472 yohN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078771.1 2858481 D 544404 CDS YP_003078772.1 254793935 8217473 complement(2858901..2859935) 1 NC_013008.1 fimbrial protein 2859935 8217473 ECSP_2907 Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003078772.1 2858901 R 544404 CDS YP_003078773.1 254793936 8217474 complement(2859946..2862426) 1 NC_013008.1 outer membrane protein 2862426 yehB 8217474 yehB Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003078773.1 2859946 R 544404 CDS YP_003078774.1 254793937 8217475 complement(2862442..2863164) 1 NC_013008.1 periplasmic pilin chaperone 2863164 yehC 8217475 yehC Escherichia coli O157:H7 str. TW14359 periplasmic pilin chaperone YP_003078774.1 2862442 R 544404 CDS YP_003078775.1 254793938 8217476 complement(2863204..2863746) 1 NC_013008.1 fimbrial-like adhesin protein 2863746 yehD 8217476 yehD Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003078775.1 2863204 R 544404 CDS YP_003078776.1 254793939 8217477 complement(2864038..2864319) 1 NC_013008.1 hypothetical protein 2864319 yehE 8217477 yehE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078776.1 2864038 R 544404 CDS YP_003078777.1 254793940 8217478 complement(2864581..2865690) 1 NC_013008.1 ATPase 2865690 mrp 8217478 mrp Escherichia coli O157:H7 str. TW14359 ATPase YP_003078777.1 2864581 R 544404 CDS YP_003078778.1 254793941 8217479 2865822..2867855 1 NC_013008.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2867855 metG 8217479 metG Escherichia coli O157:H7 str. TW14359 methionyl-tRNA synthetase YP_003078778.1 2865822 D 544404 CDS YP_003078779.1 254793942 8217480 2867996..2868724 1 NC_013008.1 regulator 2868724 8217480 ECSP_2914 Escherichia coli O157:H7 str. TW14359 regulator YP_003078779.1 2867996 D 544404 CDS YP_003078780.1 254793943 8217481 2869508..2869834 1 NC_013008.1 transposase 2869834 8217481 ECSP_2915 Escherichia coli O157:H7 str. TW14359 transposase YP_003078780.1 2869508 D 544404 CDS YP_003078781.1 254793944 8217482 2869831..2870721 1 NC_013008.1 transposase 2870721 8217482 ECSP_2916 Escherichia coli O157:H7 str. TW14359 transposase YP_003078781.1 2869831 D 544404 CDS YP_003078782.1 254793945 8217485 2876126..2879755 1 NC_013008.1 hypothetical protein 2879755 yehI 8217485 yehI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078782.1 2876126 D 544404 CDS YP_003078783.1 254793946 8217486 2879817..2880134 1 NC_013008.1 hypothetical protein 2880134 yehK 8217486 yehK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078783.1 2879817 D 544404 CDS YP_003078785.1 254793948 8217488 complement(2880559..2880711) 1 NC_013008.1 hypothetical protein 2880711 8217488 ECSP_2922 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078785.1 2880559 R 544404 CDS YP_003078787.1 254793950 8217490 2881375..2882463 1 NC_013008.1 ABC transporter ATP-binding protein 2882463 yehL 8217490 yehL Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YP_003078787.1 2881375 D 544404 CDS YP_003078788.1 254793951 8217492 2884746..2885882 1 NC_013008.1 hypothetical protein 2885882 yehP 8217492 yehP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078788.1 2884746 D 544404 CDS YP_003078789.1 254793952 8217493 2885879..2887882 1 NC_013008.1 hypothetical protein 2887882 yehQ 8217493 yehQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078789.1 2885879 D 544404 CDS YP_003078790.1 254793953 8217494 2888007..2888468 1 NC_013008.1 hypothetical protein 2888468 yehR 8217494 yehR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078790.1 2888007 D 544404 CDS YP_003078791.1 254793954 8217495 complement(2888510..2888980) 1 NC_013008.1 hypothetical protein 2888980 yehS 8217495 yehS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078791.1 2888510 R 544404 CDS YP_003078792.1 254793955 8217496 complement(2889027..2889746) 1 NC_013008.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2889746 yehT 8217496 yehT Escherichia coli O157:H7 str. TW14359 two-component response-regulatory protein YehT YP_003078792.1 2889027 R 544404 CDS YP_003078793.1 254793956 8217497 complement(2889743..2891428) 1 NC_013008.1 sensory kinase in two-component system with YehT 2891428 yehU 8217497 yehU Escherichia coli O157:H7 str. TW14359 sensory kinase in two-component system with YehT YP_003078793.1 2889743 R 544404 CDS YP_003078794.1 254793957 8217498 2891943..2892191 1 NC_013008.1 hypothetical protein 2892191 8217498 ECSP_2932 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078794.1 2891943 D 544404 CDS YP_003078795.1 254793958 8217499 complement(2892559..2892828) 1 NC_013008.1 hypothetical protein 2892828 8217499 ECSP_2933 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078795.1 2892559 R 544404 CDS YP_003078796.1 254793959 8217500 complement(2892830..2894143) 1 NC_013008.1 tail fiber protein 2894143 8217500 ECSP_2934 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003078796.1 2892830 R 544404 CDS YP_003078797.1 254793960 8217501 complement(2894208..2894807) 1 NC_013008.1 outer membrane protein Lom 2894807 8217501 ECSP_2935 Escherichia coli O157:H7 str. TW14359 outer membrane protein Lom YP_003078797.1 2894208 R 544404 CDS YP_003078798.1 254793961 8217502 complement(2894875..2898348) 1 NC_013008.1 host specificity protein J 2898348 8217502 ECSP_2936 Escherichia coli O157:H7 str. TW14359 host specificity protein J YP_003078798.1 2894875 R 544404 CDS YP_003078799.1 254793962 8217503 complement(2898589..2899167) 1 NC_013008.1 tail assembly protein 2899167 8217503 ECSP_2937 Escherichia coli O157:H7 str. TW14359 tail assembly protein YP_003078799.1 2898589 R 544404 CDS YP_003078800.1 254793963 8217504 complement(2899164..2900045) 1 NC_013008.1 tail fiber component K of prophage CP-933U 2900045 8217504 ECSP_2938 Escherichia coli O157:H7 str. TW14359 tail fiber component K of prophage CP-933U YP_003078800.1 2899164 R 544404 CDS YP_003078801.1 254793964 8217505 complement(2899918..2900616) 1 NC_013008.1 tail fiber component L of prophage CP-933U 2900616 8217505 ECSP_2939 Escherichia coli O157:H7 str. TW14359 tail fiber component L of prophage CP-933U YP_003078801.1 2899918 R 544404 CDS YP_003078802.1 254793965 8217506 complement(2900616..2900945) 1 NC_013008.1 tail fiber component M of prophage CP-933U 2900945 8217506 ECSP_2940 Escherichia coli O157:H7 str. TW14359 tail fiber component M of prophage CP-933U YP_003078802.1 2900616 R 544404 CDS YP_003078803.1 254793966 8217507 complement(2900942..2903587) 1 NC_013008.1 tail length tape measure protein 2903587 8217507 ECSP_2941 Escherichia coli O157:H7 str. TW14359 tail length tape measure protein YP_003078803.1 2900942 R 544404 CDS YP_003078804.1 254793967 8217508 complement(2903631..2903939) 1 NC_013008.1 phage tail assembly protein T 2903939 8217508 ECSP_2942 Escherichia coli O157:H7 str. TW14359 phage tail assembly protein T YP_003078804.1 2903631 R 544404 CDS YP_003078805.1 254793968 8217509 complement(2903966..2904388) 1 NC_013008.1 tail fiber component G of prophage CP-933U 2904388 8217509 ECSP_2943 Escherichia coli O157:H7 str. TW14359 tail fiber component G of prophage CP-933U YP_003078805.1 2903966 R 544404 CDS YP_003078806.1 254793969 8217510 complement(2904402..2905154) 1 NC_013008.1 tail fiber component V of prophage CP-933U 2905154 8217510 ECSP_2944 Escherichia coli O157:H7 str. TW14359 tail fiber component V of prophage CP-933U YP_003078806.1 2904402 R 544404 CDS YP_003078807.1 254793970 8217511 complement(2905162..2905560) 1 NC_013008.1 tail fiber component U of prophage CP-933U 2905560 8217511 ECSP_2945 Escherichia coli O157:H7 str. TW14359 tail fiber component U of prophage CP-933U YP_003078807.1 2905162 R 544404 CDS YP_003078808.1 254793971 8217512 complement(2905573..2906202) 1 NC_013008.1 tail fiber component Z of prophage CP-933U 2906202 8217512 ECSP_2946 Escherichia coli O157:H7 str. TW14359 tail fiber component Z of prophage CP-933U YP_003078808.1 2905573 R 544404 CDS YP_003078809.1 254793972 8217513 complement(2906199..2906480) 1 NC_013008.1 hypothetical protein 2906480 8217513 ECSP_2947 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078809.1 2906199 R 544404 CDS YP_003078810.1 254793973 8217514 complement(2906473..2906799) 1 NC_013008.1 hypothetical protein 2906799 8217514 ECSP_2948 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078810.1 2906473 R 544404 CDS YP_003078811.1 254793974 8217515 complement(2906887..2907927) 1 NC_013008.1 hypothetical protein 2907927 8217515 ECSP_2949 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078811.1 2906887 R 544404 CDS YP_003078812.1 254793975 8217516 complement(2908856..2910358) 1 NC_013008.1 head-tail preconnector protein of prophage CP-933U 2910358 8217516 ECSP_2950 Escherichia coli O157:H7 str. TW14359 head-tail preconnector protein of prophage CP-933U YP_003078812.1 2908856 R 544404 CDS YP_003078813.1 254793976 8217517 complement(2910567..2912579) 1 NC_013008.1 DNA packaging protein of prophage CP-933U 2912579 8217517 ECSP_2951 Escherichia coli O157:H7 str. TW14359 DNA packaging protein of prophage CP-933U YP_003078813.1 2910567 R 544404 CDS YP_003078814.1 254793977 8217518 complement(2912687..2913163) 1 NC_013008.1 hypothetical protein 2913163 8217518 ECSP_2952 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078814.1 2912687 R 544404 CDS YP_003078815.1 254793978 8217519 complement(2913618..2914085) 1 NC_013008.1 endopeptidase of prophage CP-933U 2914085 8217519 ECSP_2953 Escherichia coli O157:H7 str. TW14359 endopeptidase of prophage CP-933U YP_003078815.1 2913618 R 544404 CDS YP_003078816.1 254793979 8217520 complement(2914239..2914808) 1 NC_013008.1 antirepressor of prophage CP-933V 2914808 antV 8217520 antV Escherichia coli O157:H7 str. TW14359 antirepressor of prophage CP-933V YP_003078816.1 2914239 R 544404 CDS YP_003078817.1 254793980 8217521 complement(2915079..2915612) 1 NC_013008.1 endolysin R of prophage CP-933V 2915612 8217521 ECSP_2955 Escherichia coli O157:H7 str. TW14359 endolysin R of prophage CP-933V YP_003078817.1 2915079 R 544404 CDS YP_003078818.1 254793981 8217522 complement(2915617..2915889) 1 NC_013008.1 lysis protein S of prophage CP-933V 2915889 8217522 ECSP_2956 Escherichia coli O157:H7 str. TW14359 lysis protein S of prophage CP-933V YP_003078818.1 2915617 R 544404 CDS YP_003078819.1 254793982 8217523 complement(2915910..2916329) 1 NC_013008.1 hypothetical protein 2916329 8217523 ECSP_2957 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078819.1 2915910 R 544404 CDS YP_003078820.1 254793983 8217524 complement(2916512..2918458) 1 NC_013008.1 hypothetical protein 2918458 8217524 ECSP_2958 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078820.1 2916512 R 544404 CDS YP_003078821.1 254793984 8217525 2918698..2918844 1 NC_013008.1 hypothetical protein 2918844 8217525 ECSP_2959 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078821.1 2918698 D 544404 CDS YP_003078822.1 254793985 8217529 complement(2919262..2919414) 1 NC_013008.1 hypothetical protein 2919414 8217529 ECSP_2963 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078822.1 2919262 R 544404 CDS YP_003078823.1 254793986 8217530 complement(2919666..2920100) 1 NC_013008.1 antitermination protein Q of bacteriophage 2920100 8217530 ECSP_2964 Escherichia coli O157:H7 str. TW14359 antitermination protein Q of bacteriophage YP_003078823.1 2919666 R 544404 CDS YP_003078824.1 254793987 8217531 complement(2920186..2920323) 1 NC_013008.1 hypothetical protein 2920323 8217531 ECSP_2965 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078824.1 2920186 R 544404 CDS YP_003078825.1 254793988 8217532 complement(2920323..2920685) 1 NC_013008.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 2920685 8217532 ECSP_2966 Escherichia coli O157:H7 str. TW14359 endodeoxyribonuclease RUS YP_003078825.1 2920323 R 544404 CDS YP_003078826.1 254793989 8217533 complement(2920682..2920972) 1 NC_013008.1 hypothetical protein 2920972 8217533 ECSP_2967 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078826.1 2920682 R 544404 CDS YP_003078827.1 254793990 8217534 complement(2921135..2921590) 1 NC_013008.1 DLP12 prophage; hypothetical protein 2921590 8217534 ECSP_2968 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078827.1 2921135 R 544404 CDS YP_003078828.1 254793991 8217535 complement(2921805..2922602) 1 NC_013008.1 DNA-binding transcriptional regulator 2922602 8217535 ECSP_2969 Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078828.1 2921805 R 544404 CDS YP_003078829.1 254793992 8217536 complement(2922612..2923163) 1 NC_013008.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor 2923163 8217536 ECSP_2970 Escherichia coli O157:H7 str. TW14359 kinase inhibitor YP_003078829.1 2922612 R 544404 CDS YP_003078830.1 254793993 8217537 complement(2923628..2925154) 1 NC_013008.1 DLP12 prophage recombinase 2925154 8217537 ECSP_2971 Escherichia coli O157:H7 str. TW14359 DLP12 prophage recombinase YP_003078830.1 2923628 R 544404 CDS YP_003078831.1 254793994 8217538 complement(2925411..2925743) 1 NC_013008.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 2925743 emrE 8217538 emrE Escherichia coli O157:H7 str. TW14359 multidrug efflux protein YP_003078831.1 2925411 R 544404 CDS YP_003078832.1 254793995 8217539 complement(2925811..2926113) 1 NC_013008.1 Ren protein 2926113 8217539 ECSP_2973 Escherichia coli O157:H7 str. TW14359 Ren protein YP_003078832.1 2925811 R 544404 CDS YP_003078833.1 254793996 8217540 complement(2926110..2926547) 1 NC_013008.1 replication protein P 2926547 8217540 ECSP_2974 Escherichia coli O157:H7 str. TW14359 replication protein P YP_003078833.1 2926110 R 544404 CDS YP_003078834.1 254793997 8217541 2926602..2926928 1 NC_013008.1 transposase 2926928 8217541 ECSP_2975 Escherichia coli O157:H7 str. TW14359 transposase YP_003078834.1 2926602 D 544404 CDS YP_003078835.1 254793998 8217542 2926925..2927815 1 NC_013008.1 transposase 2927815 8217542 ECSP_2976 Escherichia coli O157:H7 str. TW14359 transposase YP_003078835.1 2926925 D 544404 CDS YP_003078836.1 254793999 8217543 complement(2927855..2928124) 1 NC_013008.1 replication protein P of bacteriophage 2928124 8217543 ECSP_2977 Escherichia coli O157:H7 str. TW14359 replication protein P of bacteriophage YP_003078836.1 2927855 R 544404 CDS YP_003078837.1 254794000 8217544 complement(2928121..2929140) 1 NC_013008.1 replication protein O 2929140 8217544 ECSP_2978 Escherichia coli O157:H7 str. TW14359 replication protein O YP_003078837.1 2928121 R 544404 CDS YP_003078838.1 254794001 8217545 complement(2929137..2929676) 1 NC_013008.1 bacteriophage regulatory protein 2929676 8217545 ECSP_2979 Escherichia coli O157:H7 str. TW14359 bacteriophage regulatory protein YP_003078838.1 2929137 R 544404 CDS YP_003078839.1 254794002 8217546 complement(2929746..2929976) 1 NC_013008.1 hypothetical protein 2929976 8217546 ECSP_2980 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078839.1 2929746 R 544404 CDS YP_003078840.1 254794003 8217547 2930156..2930770 1 NC_013008.1 phage-related repressor protein 2930770 8217547 ECSP_2981 Escherichia coli O157:H7 str. TW14359 phage-related repressor protein YP_003078840.1 2930156 D 544404 CDS YP_003078841.1 254794004 8217548 2930851..2931912 1 NC_013008.1 hypothetical protein 2931912 8217548 ECSP_2982 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078841.1 2930851 D 544404 CDS YP_003078842.1 254794005 8217549 2931890..2932267 1 NC_013008.1 hypothetical protein 2932267 8217549 ECSP_2983 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078842.1 2931890 D 544404 CDS YP_003078843.1 254794006 8217550 2932664..2932954 1 NC_013008.1 prophage Kil protein 2932954 kil2 8217550 kil2 Escherichia coli O157:H7 str. TW14359 prophage Kil protein YP_003078843.1 2932664 D 544404 CDS YP_003078844.1 254794007 8217551 2933030..2933326 1 NC_013008.1 protein gam 2933326 8217551 ECSP_2985 Escherichia coli O157:H7 str. TW14359 protein gam YP_003078844.1 2933030 D 544404 CDS YP_003078845.1 254794008 8217552 2933332..2934117 1 NC_013008.1 protein bet 2934117 bet2 8217552 bet2 Escherichia coli O157:H7 str. TW14359 protein bet YP_003078845.1 2933332 D 544404 CDS YP_003078846.1 254794009 8217553 2934114..2934791 1 NC_013008.1 exonuclease of prophage CP-933V 2934791 8217553 ECSP_2987 Escherichia coli O157:H7 str. TW14359 exonuclease of prophage CP-933V YP_003078846.1 2934114 D 544404 CDS YP_003078847.1 254794010 8217554 2934946..2935137 1 NC_013008.1 hypothetical protein 2935137 8217554 ECSP_2988 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078847.1 2934946 D 544404 CDS YP_003078848.1 254794011 8217555 2935148..2935429 1 NC_013008.1 hypothetical protein 2935429 8217555 ECSP_2989 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078848.1 2935148 D 544404 CDS YP_003078849.1 254794012 8217556 2935528..2935749 1 NC_013008.1 DnaK suppressor protein 2935749 8217556 ECSP_2990 Escherichia coli O157:H7 str. TW14359 DnaK suppressor protein YP_003078849.1 2935528 D 544404 CDS YP_003078850.1 254794013 8217557 2935746..2936693 1 NC_013008.1 hypothetical protein 2936693 8217557 ECSP_2991 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078850.1 2935746 D 544404 CDS YP_003078851.1 254794014 8217558 2936841..2937128 1 NC_013008.1 hypothetical protein 2937128 8217558 ECSP_2992 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078851.1 2936841 D 544404 CDS YP_003078852.1 254794015 8217560 2938008..2938250 1 NC_013008.1 hypothetical protein 2938250 8217560 ECSP_2994 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078852.1 2938008 D 544404 CDS YP_003078853.1 254794016 8217561 2938254..2938388 1 NC_013008.1 hypothetical protein 2938388 8217561 ECSP_2995 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078853.1 2938254 D 544404 CDS YP_003078854.1 254794017 8217562 2938407..2938661 1 NC_013008.1 excisionase 2938661 8217562 ECSP_2996 Escherichia coli O157:H7 str. TW14359 excisionase YP_003078854.1 2938407 D 544404 CDS YP_003078855.1 254794018 8217563 2938695..2939981 1 NC_013008.1 integrase for prophage CP-933V 2939981 intV 8217563 intV Escherichia coli O157:H7 str. TW14359 integrase for prophage CP-933V YP_003078855.1 2938695 D 544404 CDS YP_003078856.1 254794019 8217564 2940056..2940703 1 NC_013008.1 DNA-binding transcriptional regulator 2940703 mlrA 8217564 mlrA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078856.1 2940056 D 544404 CDS YP_003078857.1 254794020 8217565 2940763..2940870 1 NC_013008.1 hypothetical protein 2940870 yohO 8217565 yohO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078857.1 2940763 D 544404 CDS YP_003078858.1 254794021 8217566 complement(2940851..2941582) 1 NC_013008.1 ABC transporter membrane protein 2941582 yehW 8217566 yehW Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003078858.1 2940851 R 544404 CDS YP_003078859.1 254794022 8217567 complement(2941587..2942513) 1 NC_013008.1 ABC transporter ATP-binding protein 2942513 yehX 8217567 yehX Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YP_003078859.1 2941587 R 544404 CDS YP_003078860.1 254794023 8217568 complement(2942506..2943663) 1 NC_013008.1 ABC transporter membrane protein 2943663 yehY 8217568 yehY Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003078860.1 2942506 R 544404 CDS YP_003078861.1 254794024 8217569 complement(2943670..2944587) 1 NC_013008.1 ABC transporter periplasmic-binding protein 2944587 yehZ 8217569 yehZ Escherichia coli O157:H7 str. TW14359 ABC transporter periplasmic-binding protein YP_003078861.1 2943670 R 544404 CDS YP_003078862.1 254794025 8217570 complement(2944839..2947136) 1 NC_013008.1 beta-D-glucoside glucohydrolase 2947136 bglX 8217570 bglX Escherichia coli O157:H7 str. TW14359 beta-D-glucoside glucohydrolase YP_003078862.1 2944839 R 544404 CDS YP_003078863.1 254794026 8217571 2947332..2949047 1 NC_013008.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2949047 dld 8217571 dld Escherichia coli O157:H7 str. TW14359 D-lactate dehydrogenase YP_003078863.1 2947332 D 544404 CDS YP_003078864.1 254794027 8217572 complement(2949085..2950017) 1 NC_013008.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2950017 pbpG 8217572 pbpG Escherichia coli O157:H7 str. TW14359 D-alanyl-D-alanine endopeptidase YP_003078864.1 2949085 R 544404 CDS YP_003078865.1 254794028 8217573 complement(2950191..2950778) 1 NC_013008.1 inner membrane protein 2950778 yohC 8217573 yohC Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078865.1 2950191 R 544404 CDS YP_003078866.1 254794029 8217574 2950948..2951526 1 NC_013008.1 hypothetical protein 2951526 yohD 8217574 yohD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078866.1 2950948 D 544404 CDS YP_003078867.1 254794030 8217575 complement(2951656..2952417) 1 NC_013008.1 acetoin dehydrogenase 2952417 yohF 8217575 yohF Escherichia coli O157:H7 str. TW14359 acetoin dehydrogenase YP_003078867.1 2951656 R 544404 CDS YP_003078868.1 254794031 8217576 complement(2952470..2953906) 1 NC_013008.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2953906 yohG 8217576 yohG Escherichia coli O157:H7 str. TW14359 multidrug resistance outer membrane protein MdtQ YP_003078868.1 2952470 R 544404 CDS YP_003078869.1 254794032 8217577 complement(2954250..2954573) 1 NC_013008.1 hypothetical protein 2954573 8217577 ECSP_3011 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078869.1 2954250 R 544404 CDS YP_003078870.1 254794033 8217578 complement(2954601..2955551) 1 NC_013008.1 tRNA-dihydrouridine synthase C 2955551 dusC 8217578 dusC Escherichia coli O157:H7 str. TW14359 tRNA-dihydrouridine synthase C YP_003078870.1 2954601 R 544404 CDS YP_003078871.1 254794034 8217579 complement(2955710..2956903) 1 NC_013008.1 catalyzes the formation of catechol from salicylate; salicylate hydroxylase 2956903 8217579 ECSP_3013 Escherichia coli O157:H7 str. TW14359 salicylate hydroxylase YP_003078871.1 2955710 R 544404 CDS YP_003078872.1 254794035 8217580 complement(2956918..2957565) 1 NC_013008.1 glutathione-S-transferase 2957565 8217580 ECSP_3014 Escherichia coli O157:H7 str. TW14359 glutathione-S-transferase YP_003078872.1 2956918 R 544404 CDS YP_003078873.1 254794036 8217581 complement(2957571..2958272) 1 NC_013008.1 isomerase-decarboxylase 2958272 8217581 ECSP_3015 Escherichia coli O157:H7 str. TW14359 isomerase-decarboxylase YP_003078873.1 2957571 R 544404 CDS YP_003078874.1 254794037 8217582 complement(2958287..2959315) 1 NC_013008.1 gentisate 1,2-dioxygenase 2959315 8217582 ECSP_3016 Escherichia coli O157:H7 str. TW14359 gentisate 1,2-dioxygenase YP_003078874.1 2958287 R 544404 CDS YP_003078875.1 254794038 8217583 complement(2959327..2960685) 1 NC_013008.1 transporter 2960685 8217583 ECSP_3017 Escherichia coli O157:H7 str. TW14359 transporter YP_003078875.1 2959327 R 544404 CDS YP_003078876.1 254794039 8217584 2960764..2961720 1 NC_013008.1 regulator 2961720 8217584 ECSP_3018 Escherichia coli O157:H7 str. TW14359 regulator YP_003078876.1 2960764 D 544404 CDS YP_003078877.1 254794040 8217585 2961851..2962249 1 NC_013008.1 hypothetical protein 2962249 yohJ 8217585 yohJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078877.1 2961851 D 544404 CDS YP_003078878.1 254794041 8217586 2962246..2962941 1 NC_013008.1 hypothetical protein 2962941 yohK 8217586 yohK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078878.1 2962246 D 544404 CDS YP_003078879.1 254794042 8217587 2963071..2963955 1 NC_013008.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2963955 cdd 8217587 cdd Escherichia coli O157:H7 str. TW14359 cytidine deaminase YP_003078879.1 2963071 D 544404 CDS YP_003078880.1 254794043 8217588 2964105..2964824 1 NC_013008.1 hypothetical protein 2964824 sanA 8217588 sanA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078880.1 2964105 D 544404 CDS YP_003078881.1 254794044 8217589 2964827..2965066 1 NC_013008.1 inner membrane protein 2965066 yeiS 8217589 yeiS Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003078881.1 2964827 D 544404 CDS YP_003078882.1 254794045 8217590 2965260..2966498 1 NC_013008.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2966498 yeiT 8217590 yeiT Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003078882.1 2965260 D 544404 CDS YP_003078883.1 254794046 8217591 2966492..2967727 1 NC_013008.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2967727 yeiA 8217591 yeiA Escherichia coli O157:H7 str. TW14359 dihydropyrimidine dehydrogenase YP_003078883.1 2966492 D 544404 CDS YP_003078884.1 254794047 8217592 complement(2967970..2968980) 1 NC_013008.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 2968980 mglC 8217592 mglC Escherichia coli O157:H7 str. TW14359 beta-methylgalactoside transporter inner membrane component YP_003078884.1 2967970 R 544404 CDS YP_003078885.1 254794048 8217593 complement(2968996..2970516) 1 NC_013008.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2970516 mglA 8217593 mglA Escherichia coli O157:H7 str. TW14359 galactose/methyl galaxtoside transporter ATP-binding protein YP_003078885.1 2968996 R 544404 CDS YP_003078886.1 254794049 8217594 complement(2970577..2971575) 1 NC_013008.1 methyl-galactoside ABC transporter periplasmic-binding protein 2971575 mglB 8217594 mglB Escherichia coli O157:H7 str. TW14359 methyl-galactoside ABC transporter periplasmic-binding protein YP_003078886.1 2970577 R 544404 CDS YP_003078887.1 254794050 8217595 complement(2971854..2972894) 1 NC_013008.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2972894 galS 8217595 galS Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator GalS YP_003078887.1 2971854 R 544404 CDS YP_003078888.1 254794051 8217596 complement(2973036..2974193) 1 NC_013008.1 hypothetical protein 2974193 yeiB 8217596 yeiB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078888.1 2973036 R 544404 CDS YP_003078889.1 254794052 8217597 complement(2974210..2974878) 1 NC_013008.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2974878 folE 8217597 folE Escherichia coli O157:H7 str. TW14359 GTP cyclohydrolase I YP_003078889.1 2974210 R 544404 CDS YP_003078890.1 254794053 8217598 2975136..2975972 1 NC_013008.1 esterase 2975972 yeiG 8217598 yeiG Escherichia coli O157:H7 str. TW14359 esterase YP_003078890.1 2975136 D 544404 CDS YP_003078891.1 254794054 8217599 complement(2976004..2977983) 1 NC_013008.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2977983 cirA 8217599 cirA Escherichia coli O157:H7 str. TW14359 colicin I receptor YP_003078891.1 2976004 R 544404 CDS YP_003078892.1 254794055 8217600 complement(2978275..2979744) 1 NC_013008.1 lysine transporter 2979744 lysP 8217600 lysP Escherichia coli O157:H7 str. TW14359 lysine transporter YP_003078892.1 2978275 R 544404 CDS YP_003078893.1 254794056 8217601 complement(2979949..2980830) 1 NC_013008.1 DNA-binding transcriptional regulator 2980830 yeiE 8217601 yeiE Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078893.1 2979949 R 544404 CDS YP_003078894.1 254794057 8217602 2980929..2981978 1 NC_013008.1 hypothetical protein 2981978 yeiH 8217602 yeiH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078894.1 2980929 D 544404 CDS YP_003078895.1 254794058 8217603 2982052..2982909 1 NC_013008.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2982909 nfo 8217603 nfo Escherichia coli O157:H7 str. TW14359 endonuclease IV YP_003078895.1 2982052 D 544404 CDS YP_003078896.1 254794059 8217604 2982912..2984000 1 NC_013008.1 hypothetical protein 2984000 yeiI 8217604 yeiI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078896.1 2982912 D 544404 CDS YP_003078897.1 254794060 8217605 complement(2984056..2985306) 1 NC_013008.1 transport system permease 2985306 yeiJ 8217605 yeiJ Escherichia coli O157:H7 str. TW14359 transport system permease YP_003078897.1 2984056 R 544404 CDS YP_003078898.1 254794061 8217606 complement(2985406..2986347) 1 NC_013008.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2986347 rihB 8217606 rihB Escherichia coli O157:H7 str. TW14359 ribonucleoside hydrolase 2 YP_003078898.1 2985406 R 544404 CDS YP_003078899.1 254794062 8217607 2986516..2987175 1 NC_013008.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2987175 yeiL 8217607 yeiL Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator YeiL YP_003078899.1 2986516 D 544404 CDS YP_003078900.1 254794063 8217608 complement(2987246..2988496) 1 NC_013008.1 nucleoside transporter 2988496 yeiM 8217608 yeiM Escherichia coli O157:H7 str. TW14359 nucleoside transporter YP_003078900.1 2987246 R 544404 CDS YP_003078901.1 254794064 8217609 complement(2988590..2989528) 1 NC_013008.1 hypothetical protein 2989528 yeiN 8217609 yeiN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078901.1 2988590 R 544404 CDS YP_003078902.1 254794065 8217610 complement(2989516..2990457) 1 NC_013008.1 hypothetical protein 2990457 yeiC 8217610 yeiC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078902.1 2989516 R 544404 CDS YP_003078903.1 254794066 8217611 complement(2990881..2992572) 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC 2992572 fruA 8217611 fruA Escherichia coli O157:H7 str. TW14359 PTS system fructose-specific transporter subunits IIBC YP_003078903.1 2990881 R 544404 CDS YP_003078904.1 254794067 8217612 complement(2992589..2993527) 1 NC_013008.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2993527 fruK 8217612 fruK Escherichia coli O157:H7 str. TW14359 1-phosphofructokinase YP_003078904.1 2992589 R 544404 CDS YP_003078905.1 254794068 8217613 complement(2993527..2994657) 1 NC_013008.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 2994657 fruB 8217613 fruB Escherichia coli O157:H7 str. TW14359 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_003078905.1 2993527 R 544404 CDS YP_003078906.1 254794069 8217614 2994823..2994954 1 NC_013008.1 hypothetical protein 2994954 8217614 ECSP_3048 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078906.1 2994823 D 544404 CDS YP_003078907.1 254794070 8217615 2995025..2996206 1 NC_013008.1 lactose/glucose efflux system 2996206 setB 8217615 setB Escherichia coli O157:H7 str. TW14359 lactose/glucose efflux system YP_003078907.1 2995025 D 544404 CDS YP_003078908.1 254794071 8217616 complement(2996203..2996457) 1 NC_013008.1 hypothetical protein 2996457 yeiW 8217616 yeiW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078908.1 2996203 R 544404 CDS YP_003078909.1 254794072 8217617 2996612..2997184 1 NC_013008.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2997184 yeiP 8217617 yeiP Escherichia coli O157:H7 str. TW14359 elongation factor P YP_003078909.1 2996612 D 544404 CDS YP_003078910.1 254794073 8217618 2997407..2998873 1 NC_013008.1 dehydrogenase, NAD-dependent 2998873 yeiQ 8217618 yeiQ Escherichia coli O157:H7 str. TW14359 dehydrogenase, NAD-dependent YP_003078910.1 2997407 D 544404 CDS YP_003078911.1 254794074 8217619 2998991..2999977 1 NC_013008.1 hypothetical protein 2999977 yeiR 8217619 yeiR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078911.1 2998991 D 544404 CDS YP_003078912.1 254794075 8217620 3000016..3000729 1 NC_013008.1 UDP pyrophosphate phosphatase 3000729 yeiU 8217620 yeiU Escherichia coli O157:H7 str. TW14359 UDP pyrophosphate phosphatase YP_003078912.1 3000016 D 544404 CDS YP_003078913.1 254794076 8217621 3001142..3001708 1 NC_013008.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 3001708 spr 8217621 spr Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003078913.1 3001142 D 544404 CDS YP_003078914.1 254794077 8217622 3001889..3003445 1 NC_013008.1 hypothetical protein 3003445 rtn 8217622 rtn Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078914.1 3001889 D 544404 CDS YP_003078915.1 254794078 8217623 3003527..3005341 1 NC_013008.1 oligopeptide transporter subunit; periplasmic-binding component of ABC superfamily 3005341 yejA 8217623 yejA Escherichia coli O157:H7 str. TW14359 oligopeptide transporter subunit; periplasmic-binding component of ABC superfamily YP_003078915.1 3003527 D 544404 CDS YP_003078916.1 254794079 8217624 3005342..3006436 1 NC_013008.1 oligopeptide ABC transporter membrane protein 3006436 yejB 8217624 yejB Escherichia coli O157:H7 str. TW14359 oligopeptide ABC transporter membrane protein YP_003078916.1 3005342 D 544404 CDS YP_003078917.1 254794080 8217625 3006436..3007461 1 NC_013008.1 oligopeptide ABC transporter membrane protein 3007461 yejE 8217625 yejE Escherichia coli O157:H7 str. TW14359 oligopeptide ABC transporter membrane protein YP_003078917.1 3006436 D 544404 CDS YP_003078918.1 254794081 8217626 3007463..3009052 1 NC_013008.1 fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding proteins 3009052 yejF 8217626 yejF Escherichia coli O157:H7 str. TW14359 fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding proteins YP_003078918.1 3007463 D 544404 CDS YP_003078919.1 254794082 8217627 complement(3009056..3009400) 1 NC_013008.1 hypothetical protein 3009400 yejG 8217627 yejG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078919.1 3009056 R 544404 CDS YP_003078920.1 254794083 8217628 complement(3009733..3010923) 1 NC_013008.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 3010923 bcr 8217628 bcr Escherichia coli O157:H7 str. TW14359 bicyclomycin/multidrug efflux system YP_003078920.1 3009733 R 544404 CDS YP_003078921.1 254794084 8217629 complement(3010951..3011646) 1 NC_013008.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 3011646 rsuA 8217629 rsuA Escherichia coli O157:H7 str. TW14359 16S rRNA pseudouridylate synthase A YP_003078921.1 3010951 R 544404 CDS YP_003078922.1 254794085 8217630 3011795..3013555 1 NC_013008.1 ATP-dependent helicase 3013555 yejH 8217630 yejH Escherichia coli O157:H7 str. TW14359 ATP-dependent helicase YP_003078922.1 3011795 D 544404 CDS YP_003078923.1 254794086 8217631 3013680..3013964 1 NC_013008.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3013964 rplY 8217631 rplY Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L25 YP_003078923.1 3013680 D 544404 CDS YP_003078924.1 254794087 8217632 complement(3014103..3015110) 1 NC_013008.1 nucleoid-associated protein NdpA 3015110 yejK 8217632 yejK Escherichia coli O157:H7 str. TW14359 nucleoid-associated protein NdpA YP_003078924.1 3014103 R 544404 CDS YP_003078925.1 254794088 8217633 complement(3015155..3015271) 1 NC_013008.1 hypothetical protein 3015271 8217633 ECSP_3067 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078925.1 3015155 R 544404 CDS YP_003078926.1 254794089 8217634 3015292..3015519 1 NC_013008.1 hypothetical protein 3015519 yejL 8217634 yejL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078926.1 3015292 D 544404 CDS YP_003078927.1 254794090 8217635 3015539..3017299 1 NC_013008.1 hydrolase 3017299 yejM 8217635 yejM Escherichia coli O157:H7 str. TW14359 hydrolase YP_003078927.1 3015539 D 544404 CDS YP_003078928.1 254794091 8217637 complement(3017551..3020142) 1 NC_013008.1 autotransporter outer membrane protein 3020142 yejO 8217637 yejO Escherichia coli O157:H7 str. TW14359 autotransporter outer membrane protein YP_003078928.1 3017551 R 544404 CDS YP_003078929.1 254794092 8217638 3020462..3021109 1 NC_013008.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 3021109 narP 8217638 narP Escherichia coli O157:H7 str. TW14359 transcriptional regulator NarP YP_003078929.1 3020462 D 544404 CDS YP_003078930.1 254794093 8217639 complement(3021144..3022196) 1 NC_013008.1 heme lyase CcmH 3022196 ccmH 8217639 ccmH Escherichia coli O157:H7 str. TW14359 heme lyase CcmH YP_003078930.1 3021144 R 544404 CDS YP_003078931.1 254794094 8217640 complement(3022193..3022750) 1 NC_013008.1 periplasmic thioredoxin of cytochrome c-type biogenesis 3022750 ccmG 8217640 ccmG Escherichia coli O157:H7 str. TW14359 periplasmic thioredoxin of cytochrome c-type biogenesis YP_003078931.1 3022193 R 544404 CDS YP_003078932.1 254794095 8217641 complement(3022747..3024690) 1 NC_013008.1 heme lyase CcmF 3024690 ccmF 8217641 ccmF Escherichia coli O157:H7 str. TW14359 heme lyase CcmF YP_003078932.1 3022747 R 544404 CDS YP_003078933.1 254794096 8217642 complement(3024687..3025166) 1 NC_013008.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 3025166 ccmE 8217642 ccmE Escherichia coli O157:H7 str. TW14359 cytochrome c-type biogenesis protein CcmE YP_003078933.1 3024687 R 544404 CDS YP_003078934.1 254794097 8217643 complement(3025163..3025372) 1 NC_013008.1 cytochrome c biogenesis protein 3025372 ccmD 8217643 ccmD Escherichia coli O157:H7 str. TW14359 cytochrome c biogenesis protein YP_003078934.1 3025163 R 544404 CDS YP_003078935.1 254794098 8217644 complement(3025369..3026106) 1 NC_013008.1 heme ABC transporter membrane protein 3026106 ccmC 8217644 ccmC Escherichia coli O157:H7 str. TW14359 heme ABC transporter membrane protein YP_003078935.1 3025369 R 544404 CDS YP_003078936.1 254794099 8217645 complement(3026148..3026810) 1 NC_013008.1 heme ABC transporter membrane protein 3026810 ccmB 8217645 ccmB Escherichia coli O157:H7 str. TW14359 heme ABC transporter membrane protein YP_003078936.1 3026148 R 544404 CDS YP_003078937.1 254794100 8217646 complement(3026807..3027430) 1 NC_013008.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 3027430 ccmA 8217646 ccmA Escherichia coli O157:H7 str. TW14359 cytochrome c biogenesis protein CcmA YP_003078937.1 3026807 R 544404 CDS YP_003078938.1 254794101 8217647 complement(3027443..3028045) 1 NC_013008.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 3028045 napC 8217647 napC Escherichia coli O157:H7 str. TW14359 cytochrome c-type protein NapC YP_003078938.1 3027443 R 544404 CDS YP_003078939.1 254794102 8217648 complement(3028055..3028504) 1 NC_013008.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 3028504 napB 8217648 napB Escherichia coli O157:H7 str. TW14359 citrate reductase cytochrome c-type subunit YP_003078939.1 3028055 R 544404 CDS YP_003078940.1 254794103 8217649 complement(3028501..3029364) 1 NC_013008.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 3029364 napH 8217649 napH Escherichia coli O157:H7 str. TW14359 quinol dehydrogenase membrane component YP_003078940.1 3028501 R 544404 CDS YP_003078941.1 254794104 8217650 complement(3029351..3030046) 1 NC_013008.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 3030046 napG 8217650 napG Escherichia coli O157:H7 str. TW14359 quinol dehydrogenase periplasmic component YP_003078941.1 3029351 R 544404 CDS YP_003078942.1 254794105 8217651 complement(3030053..3032539) 1 NC_013008.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 3032539 napA 8217651 napA Escherichia coli O157:H7 str. TW14359 nitrate reductase catalytic subunit YP_003078942.1 3030053 R 544404 CDS YP_003078943.1 254794106 8217652 complement(3032536..3032799) 1 NC_013008.1 assembly protein for periplasmic nitrate reductase 3032799 napD 8217652 napD Escherichia coli O157:H7 str. TW14359 assembly protein for periplasmic nitrate reductase YP_003078943.1 3032536 R 544404 CDS YP_003078944.1 254794107 8217653 complement(3032789..3033283) 1 NC_013008.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 3033283 napF 8217653 napF Escherichia coli O157:H7 str. TW14359 ferredoxin-type protein YP_003078944.1 3032789 R 544404 CDS YP_003078945.1 254794108 8217654 3033690..3034178 1 NC_013008.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 3034178 eco 8217654 eco Escherichia coli O157:H7 str. TW14359 ecotin YP_003078945.1 3033690 D 544404 CDS YP_003078946.1 254794109 8217655 complement(3034328..3035974) 1 NC_013008.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 3035974 mqo 8217655 mqo Escherichia coli O157:H7 str. TW14359 malate:quinone oxidoreductase YP_003078946.1 3034328 R 544404 CDS YP_003078947.1 254794110 8217656 complement(3036192..3037835) 1 NC_013008.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding protein 3037835 8217656 ECSP_3090 Escherichia coli O157:H7 str. TW14359 multidrug transporter membrane component/ATP-binding protein YP_003078947.1 3036192 R 544404 CDS YP_003078948.1 254794111 8217657 complement(3037911..3038561) 1 NC_013008.1 N1-methyladenine or N3-methylcytosine DNA lesion oxidative demethylase 3038561 alkB 8217657 alkB Escherichia coli O157:H7 str. TW14359 N1-methyladenine or N3-methylcytosine DNA lesion oxidative demethylase YP_003078948.1 3037911 R 544404 CDS YP_003078949.1 254794112 8217658 complement(3038561..3039625) 1 NC_013008.1 fused DNA-binding transcriptional dual regulator, O6-methylguanine-DNA methyltransferase 3039625 ada 8217658 ada Escherichia coli O157:H7 str. TW14359 fused DNA-binding transcriptional dual regulator, O6-methylguanine-DNA methyltransferase YP_003078949.1 3038561 R 544404 CDS YP_003078950.1 254794113 8217659 complement(3039699..3040754) 1 NC_013008.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 3040754 yojL 8217659 yojL Escherichia coli O157:H7 str. TW14359 thiamine biosynthesis lipoprotein ApbE YP_003078950.1 3039699 R 544404 CDS YP_003078951.1 254794114 8217660 complement(3040866..3041969) 1 NC_013008.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 3041969 ompC 8217660 ompC Escherichia coli O157:H7 str. TW14359 outer membrane porin protein C YP_003078951.1 3040866 R 544404 CDS YP_003078952.1 254794115 8217661 complement(3042361..3042486) 1 NC_013008.1 hypothetical protein 3042486 8217661 ECSP_3095 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078952.1 3042361 R 544404 CDS YP_003078953.1 254794116 8217662 3042708..3045380 1 NC_013008.1 phosphotransfer intermediate protein in two-component regulatory system with RcsBC 3045380 rcsD 8217662 rcsD Escherichia coli O157:H7 str. TW14359 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_003078953.1 3042708 D 544404 CDS YP_003078954.1 254794117 8217663 3045397..3046047 1 NC_013008.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 3046047 rcsB 8217663 rcsB Escherichia coli O157:H7 str. TW14359 transcriptional regulator RcsB YP_003078954.1 3045397 D 544404 CDS YP_003078955.1 254794118 8217664 complement(3046247..3049096) 1 NC_013008.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN 3049096 rcsC 8217664 rcsC Escherichia coli O157:H7 str. TW14359 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_003078955.1 3046247 R 544404 CDS YP_003078956.1 254794119 8217665 complement(3049371..3050147) 1 NC_013008.1 hypothetical protein 3050147 yfaP 8217665 yfaP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078956.1 3049371 R 544404 CDS YP_003078957.1 254794120 8217667 complement(3051802..3056406) 1 NC_013008.1 hypothetical protein 3056406 8217667 ECSP_3101 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078957.1 3051802 R 544404 CDS YP_003078958.1 254794121 8217668 complement(3056340..3056963) 1 NC_013008.1 hypothetical protein 3056963 yfaT 8217668 yfaT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078958.1 3056340 R 544404 CDS YP_003078959.1 254794122 8217670 complement(3058796..3061423) 1 NC_013008.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 3061423 gyrA 8217670 gyrA Escherichia coli O157:H7 str. TW14359 DNA gyrase subunit A YP_003078959.1 3058796 R 544404 CDS YP_003078960.1 254794123 8217671 3061570..3062292 1 NC_013008.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 3062292 ubiG 8217671 ubiG Escherichia coli O157:H7 str. TW14359 3-demethylubiquinone-9 3-methyltransferase YP_003078960.1 3061570 D 544404 CDS YP_003078961.1 254794124 8217672 complement(3062433..3066185) 1 NC_013008.1 adhesin 3066185 yfaL 8217672 yfaL Escherichia coli O157:H7 str. TW14359 adhesin YP_003078961.1 3062433 R 544404 CDS YP_003078962.1 254794125 8217673 3066881..3069166 1 NC_013008.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3069166 nrdA 8217673 nrdA Escherichia coli O157:H7 str. TW14359 ribonucleotide-diphosphate reductase subunit alpha YP_003078962.1 3066881 D 544404 CDS YP_003078963.1 254794126 8217674 3069393..3070523 1 NC_013008.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 3070523 nrdB 8217674 nrdB Escherichia coli O157:H7 str. TW14359 ribonucleotide-diphosphate reductase subunit beta YP_003078963.1 3069393 D 544404 CDS YP_003078964.1 254794127 8217675 3070523..3070777 1 NC_013008.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 3070777 yfaE 8217675 yfaE Escherichia coli O157:H7 str. TW14359 2Fe-2S ferredoxin YP_003078964.1 3070523 D 544404 CDS YP_003078965.1 254794128 8217676 complement(3070831..3071481) 1 NC_013008.1 hypothetical protein 3071481 inaA 8217676 inaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078965.1 3070831 R 544404 CDS YP_003078966.1 254794129 8217677 complement(3071562..3072752) 1 NC_013008.1 antibiotic efflux protein 3072752 8217677 ECSP_3111 Escherichia coli O157:H7 str. TW14359 antibiotic efflux protein YP_003078966.1 3071562 R 544404 CDS YP_003078967.1 254794130 8217678 3072904..3073782 1 NC_013008.1 regulator 3073782 8217678 ECSP_3112 Escherichia coli O157:H7 str. TW14359 regulator YP_003078967.1 3072904 D 544404 CDS YP_003078968.1 254794131 8217679 3074246..3075316 1 NC_013008.1 hypothetical protein 3075316 8217679 ECSP_3113 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078968.1 3074246 D 544404 CDS YP_003078969.1 254794132 8217680 complement(3075540..3076616) 1 NC_013008.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 3076616 glpQ 8217680 glpQ Escherichia coli O157:H7 str. TW14359 glycerophosphodiester phosphodiesterase YP_003078969.1 3075540 R 544404 CDS YP_003078970.1 254794133 8217681 complement(3076621..3077979) 1 NC_013008.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 3077979 glpT 8217681 glpT Escherichia coli O157:H7 str. TW14359 sn-glycerol-3-phosphate transporter YP_003078970.1 3076621 R 544404 CDS YP_003078971.1 254794134 8217682 3078252..3079880 1 NC_013008.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 3079880 glpA 8217682 glpA Escherichia coli O157:H7 str. TW14359 sn-glycerol-3-phosphate dehydrogenase subunit A YP_003078971.1 3078252 D 544404 CDS YP_003078972.1 254794135 8217683 3079870..3081129 1 NC_013008.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 3081129 glpB 8217683 glpB Escherichia coli O157:H7 str. TW14359 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_003078972.1 3079870 D 544404 CDS YP_003078973.1 254794136 8217684 3081126..3082316 1 NC_013008.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 3082316 glpC 8217684 glpC Escherichia coli O157:H7 str. TW14359 sn-glycerol-3-phosphate dehydrogenase subunit C YP_003078973.1 3081126 D 544404 CDS YP_003078974.1 254794137 8217685 3082509..3083435 1 NC_013008.1 hypothetical protein 3083435 yfaD 8217685 yfaD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078974.1 3082509 D 544404 CDS YP_003078975.1 254794138 8217686 complement(3083476..3084228) 1 NC_013008.1 aldolase 3084228 yfaU 8217686 yfaU Escherichia coli O157:H7 str. TW14359 aldolase YP_003078975.1 3083476 R 544404 CDS YP_003078976.1 254794139 8217687 complement(3084296..3085054) 1 NC_013008.1 transporter 3085054 yfaV 8217687 yfaV Escherichia coli O157:H7 str. TW14359 transporter YP_003078976.1 3084296 R 544404 CDS YP_003078977.1 254794140 8217688 3085125..3085451 1 NC_013008.1 transposase 3085451 8217688 ECSP_3122 Escherichia coli O157:H7 str. TW14359 transposase YP_003078977.1 3085125 D 544404 CDS YP_003078978.1 254794141 8217689 3085448..3086338 1 NC_013008.1 transposase 3086338 8217689 ECSP_3123 Escherichia coli O157:H7 str. TW14359 transposase YP_003078978.1 3085448 D 544404 CDS YP_003078979.1 254794142 8217690 complement(3086955..3088172) 1 NC_013008.1 enolase 3088172 yfaW 8217690 yfaW Escherichia coli O157:H7 str. TW14359 enolase YP_003078979.1 3086955 R 544404 CDS YP_003078980.1 254794143 8217691 complement(3088175..3088957) 1 NC_013008.1 DNA-binding transcriptional regulator 3088957 yfaX 8217691 yfaX Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003078980.1 3088175 R 544404 CDS YP_003078981.1 254794144 8217692 complement(3089177..3090379) 1 NC_013008.1 competence damage-inducible protein A 3090379 yfaY 8217692 yfaY Escherichia coli O157:H7 str. TW14359 competence damage-inducible protein A YP_003078981.1 3089177 R 544404 CDS YP_003078982.1 254794145 8217693 complement(3090479..3091021) 1 NC_013008.1 outer membrane porin protein 3091021 yfaZ 8217693 yfaZ Escherichia coli O157:H7 str. TW14359 outer membrane porin protein YP_003078982.1 3090479 R 544404 CDS YP_003078983.1 254794146 8217694 3091300..3091725 1 NC_013008.1 hypothetical protein 3091725 yfaO 8217694 yfaO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078983.1 3091300 D 544404 CDS YP_003078984.1 254794147 8217695 complement(3091764..3092366) 1 NC_013008.1 hypothetical protein 3092366 ais 8217695 ais Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078984.1 3091764 R 544404 CDS YP_003078985.1 254794148 8217696 3092674..3093813 1 NC_013008.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 3093813 arnB 8217696 arnB Escherichia coli O157:H7 str. TW14359 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_003078985.1 3092674 D 544404 CDS YP_003078986.1 254794149 8217697 3093817..3094785 1 NC_013008.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; UDP phosphate 4-deoxy-4-formamido-L-arabinose transferase 3094785 arnC 8217697 arnC Escherichia coli O157:H7 str. TW14359 UDP phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_003078986.1 3093817 D 544404 CDS YP_003078987.1 254794150 8217698 3094785..3096767 1 NC_013008.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 3096767 arnA 8217698 arnA Escherichia coli O157:H7 str. TW14359 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_003078987.1 3094785 D 544404 CDS YP_003078988.1 254794151 8217699 3096764..3097654 1 NC_013008.1 hypothetical protein 3097654 yfbH 8217699 yfbH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078988.1 3096764 D 544404 CDS YP_003078989.1 254794152 8217700 3097654..3099306 1 NC_013008.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 3099306 arnT 8217700 arnT Escherichia coli O157:H7 str. TW14359 4-amino-4-deoxy-L-arabinose transferase YP_003078989.1 3097654 D 544404 CDS YP_003078990.1 254794153 8217701 3099303..3099638 1 NC_013008.1 hypothetical protein 3099638 yfbW 8217701 yfbW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078990.1 3099303 D 544404 CDS YP_003078991.1 254794154 8217702 3099638..3100024 1 NC_013008.1 hypothetical protein 3100024 yfbJ 8217702 yfbJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078991.1 3099638 D 544404 CDS YP_003078992.1 254794155 8217703 complement(3100018..3100284) 1 NC_013008.1 polymyxin resistance protein B 3100284 pmrD 8217703 pmrD Escherichia coli O157:H7 str. TW14359 polymyxin resistance protein B YP_003078992.1 3100018 R 544404 CDS YP_003078993.1 254794156 8217704 complement(3100394..3101749) 1 NC_013008.1 O-succinylbenzoic acid--CoA ligase 3101749 menE 8217704 menE Escherichia coli O157:H7 str. TW14359 O-succinylbenzoic acid--CoA ligase YP_003078993.1 3100394 R 544404 CDS YP_003078994.1 254794157 8217705 complement(3101746..3102708) 1 NC_013008.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 3102708 menC 8217705 menC Escherichia coli O157:H7 str. TW14359 O-succinylbenzoate synthase YP_003078994.1 3101746 R 544404 CDS YP_003078995.1 254794158 8217706 complement(3102708..3103565) 1 NC_013008.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 3103565 menB 8217706 menB Escherichia coli O157:H7 str. TW14359 naphthoate synthase YP_003078995.1 3102708 R 544404 CDS YP_003078996.1 254794159 8217707 complement(3103580..3104338) 1 NC_013008.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 3104338 yfbB 8217707 yfbB Escherichia coli O157:H7 str. TW14359 acyl-CoA thioester hydrolase YP_003078996.1 3103580 R 544404 CDS YP_003078997.1 254794160 8217708 complement(3104335..3106005) 1 NC_013008.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 3106005 menD 8217708 menD Escherichia coli O157:H7 str. TW14359 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_003078997.1 3104335 R 544404 CDS YP_003078998.1 254794161 8217709 complement(3106094..3107389) 1 NC_013008.1 isochorismate synthase 2 3107389 menF 8217709 menF Escherichia coli O157:H7 str. TW14359 isochorismate synthase 2 YP_003078998.1 3106094 R 544404 CDS YP_003078999.1 254794162 8217710 complement(3107468..3107773) 1 NC_013008.1 hypothetical protein 3107773 elaB 8217710 elaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003078999.1 3107468 R 544404 CDS YP_003079000.1 254794163 8217711 complement(3107828..3108289) 1 NC_013008.1 hypothetical protein 3108289 elaA 8217711 elaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079000.1 3107828 R 544404 CDS YP_003079001.1 254794164 8217712 3108354..3109271 1 NC_013008.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 3109271 rbn 8217712 rbn Escherichia coli O157:H7 str. TW14359 ribonuclease Z YP_003079001.1 3108354 D 544404 CDS YP_003079002.1 254794165 8217713 3109459..3110682 1 NC_013008.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 3110682 elaD 8217713 elaD Escherichia coli O157:H7 str. TW14359 deubiquitinase YP_003079002.1 3109459 D 544404 CDS YP_003079003.1 254794166 8217714 3111469..3111711 1 NC_013008.1 peptidase 3111711 yfbL 8217714 yfbL Escherichia coli O157:H7 str. TW14359 peptidase YP_003079003.1 3111469 D 544404 CDS YP_003079004.1 254794167 8217715 3111814..3112317 1 NC_013008.1 hypothetical protein 3112317 yfbM 8217715 yfbM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079004.1 3111814 D 544404 CDS YP_003079005.1 254794168 8217716 complement(3112384..3113841) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 3113841 nuoN 8217716 nuoN Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit N YP_003079005.1 3112384 R 544404 CDS YP_003079006.1 254794169 8217717 complement(3113848..3115377) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 3115377 nuoM 8217717 nuoM Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit M YP_003079006.1 3113848 R 544404 CDS YP_003079007.1 254794170 8217718 complement(3115608..3117449) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 3117449 nuoL 8217718 nuoL Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit L YP_003079007.1 3115608 R 544404 CDS YP_003079008.1 254794171 8217719 complement(3117446..3117748) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 3117748 nuoK 8217719 nuoK Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit K YP_003079008.1 3117446 R 544404 CDS YP_003079009.1 254794172 8217720 complement(3117745..3118299) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 3118299 nuoJ 8217720 nuoJ Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit J YP_003079009.1 3117745 R 544404 CDS YP_003079010.1 254794173 8217721 complement(3118311..3118853) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 3118853 nuoI 8217721 nuoI Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit I YP_003079010.1 3118311 R 544404 CDS YP_003079011.1 254794174 8217722 complement(3118868..3119845) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 3119845 nuoH 8217722 nuoH Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit H YP_003079011.1 3118868 R 544404 CDS YP_003079012.1 254794175 8217723 complement(3119842..3122568) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 3122568 nuoG 8217723 nuoG Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit G YP_003079012.1 3119842 R 544404 CDS YP_003079013.1 254794176 8217724 complement(3122621..3123958) 1 NC_013008.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 3123958 nuoF 8217724 nuoF Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase I subunit F YP_003079013.1 3122621 R 544404 CDS YP_003079014.1 254794177 8217725 complement(3123955..3124455) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 3124455 nuoE 8217725 nuoE Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit E YP_003079014.1 3123955 R 544404 CDS YP_003079015.1 254794178 8217726 complement(3124458..3126248) 1 NC_013008.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 3126248 nuoC 8217726 nuoC Escherichia coli O157:H7 str. TW14359 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_003079015.1 3124458 R 544404 CDS YP_003079016.1 254794179 8217727 complement(3126354..3127016) 1 NC_013008.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3127016 nuoB 8217727 nuoB Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit B YP_003079016.1 3126354 R 544404 CDS YP_003079017.1 254794180 8217728 complement(3127032..3127475) 1 NC_013008.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 3127475 nuoA 8217728 nuoA Escherichia coli O157:H7 str. TW14359 NADH dehydrogenase subunit A YP_003079017.1 3127032 R 544404 CDS YP_003079018.1 254794181 8217729 complement(3128106..3129044) 1 NC_013008.1 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes 3129044 lrhA 8217729 lrhA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes YP_003079018.1 3128106 R 544404 CDS YP_003079019.1 254794182 8217730 3129964..3131181 1 NC_013008.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 3131181 yfbQ 8217730 yfbQ Escherichia coli O157:H7 str. TW14359 aminotransferase YP_003079019.1 3129964 D 544404 CDS YP_003079020.1 254794183 8217731 3131265..3131864 1 NC_013008.1 hypothetical protein 3131864 yfbR 8217731 yfbR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079020.1 3131265 D 544404 CDS YP_003079021.1 254794184 8217732 complement(3131923..3133755) 1 NC_013008.1 transporter 3133755 yfbS 8217732 yfbS Escherichia coli O157:H7 str. TW14359 transporter YP_003079021.1 3131923 R 544404 CDS YP_003079022.1 254794185 8217733 complement(3133842..3134492) 1 NC_013008.1 phosphatase 3134492 yfbT 8217733 yfbT Escherichia coli O157:H7 str. TW14359 phosphatase YP_003079022.1 3133842 R 544404 CDS YP_003079023.1 254794186 8217734 complement(3134503..3134997) 1 NC_013008.1 hypothetical protein 3134997 yfbU 8217734 yfbU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079023.1 3134503 R 544404 CDS YP_003079024.1 254794187 8217735 complement(3135080..3135535) 1 NC_013008.1 hypothetical protein 3135535 yfbV 8217735 yfbV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079024.1 3135080 R 544404 CDS YP_003079025.1 254794188 8217736 complement(3135604..3135735) 1 NC_013008.1 hypothetical protein 3135735 8217736 ECSP_3170 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079025.1 3135604 R 544404 CDS YP_003079026.1 254794189 8217737 3135873..3137075 1 NC_013008.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 3137075 ackA 8217737 ackA Escherichia coli O157:H7 str. TW14359 acetate kinase YP_003079026.1 3135873 D 544404 CDS YP_003079027.1 254794190 8217738 3137150..3139294 1 NC_013008.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 3139294 pta 8217738 pta Escherichia coli O157:H7 str. TW14359 phosphate acetyltransferase YP_003079027.1 3137150 D 544404 CDS YP_003079028.1 254794191 8217739 3139484..3141004 1 NC_013008.1 hypothetical protein 3141004 yfcC 8217739 yfcC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079028.1 3139484 D 544404 CDS YP_003079029.1 254794192 8217740 complement(3141037..3141579) 1 NC_013008.1 NUDIX hydrolase 3141579 yfcD 8217740 yfcD Escherichia coli O157:H7 str. TW14359 NUDIX hydrolase YP_003079029.1 3141037 R 544404 CDS YP_003079030.1 254794193 8217741 complement(3141637..3142191) 1 NC_013008.1 phosphodiesterase 3142191 yfcE 8217741 yfcE Escherichia coli O157:H7 str. TW14359 phosphodiesterase YP_003079030.1 3141637 R 544404 CDS YP_003079031.1 254794194 8217742 complement(3142244..3142888) 1 NC_013008.1 hypothetical protein 3142888 yfcF 8217742 yfcF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079031.1 3142244 R 544404 CDS YP_003079032.1 254794195 8217743 3143024..3143671 1 NC_013008.1 glutathione S-transferase 3143671 yfcG 8217743 yfcG Escherichia coli O157:H7 str. TW14359 glutathione S-transferase YP_003079032.1 3143024 D 544404 CDS YP_003079033.1 254794196 8217744 3143728..3144090 1 NC_013008.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 3144090 folX 8217744 folX Escherichia coli O157:H7 str. TW14359 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_003079033.1 3143728 D 544404 CDS YP_003079034.1 254794197 8217745 3144111..3145004 1 NC_013008.1 hypothetical protein 3145004 yfcH 8217745 yfcH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079034.1 3144111 D 544404 CDS YP_003079035.1 254794198 8217746 complement(3145052..3145942) 1 NC_013008.1 transposase 3145942 yfcI 8217746 yfcI Escherichia coli O157:H7 str. TW14359 transposase YP_003079035.1 3145052 R 544404 CDS YP_003079036.1 254794199 8217747 complement(3146139..3146912) 1 NC_013008.1 histidine/lysine/arginine/ornithine transporter subunit 3146912 hisP 8217747 hisP Escherichia coli O157:H7 str. TW14359 histidine/lysine/arginine/ornithine transporter subunit YP_003079036.1 3146139 R 544404 CDS YP_003079037.1 254794200 8217748 complement(3146920..3147636) 1 NC_013008.1 histidine/lysine/arginine/ornithine ABC transporter membrane protein 3147636 hisM 8217748 hisM Escherichia coli O157:H7 str. TW14359 histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_003079037.1 3146920 R 544404 CDS YP_003079038.1 254794201 8217749 complement(3147633..3148319) 1 NC_013008.1 histidine/lysine/arginine/ornithine ABC transporter membrane protein 3148319 hisQ 8217749 hisQ Escherichia coli O157:H7 str. TW14359 histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_003079038.1 3147633 R 544404 CDS YP_003079039.1 254794202 8217750 complement(3148409..3149191) 1 NC_013008.1 histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein 3149191 hisJ 8217750 hisJ Escherichia coli O157:H7 str. TW14359 histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_003079039.1 3148409 R 544404 CDS YP_003079040.1 254794203 8217751 complement(3149412..3150194) 1 NC_013008.1 lysine/arginine/ornithine ABC transporter periplasmic-binding protein 3150194 argT 8217751 argT Escherichia coli O157:H7 str. TW14359 lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_003079040.1 3149412 R 544404 CDS YP_003079041.1 254794204 8217752 complement(3150460..3151029) 1 NC_013008.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3151029 ubiX 8217752 ubiX Escherichia coli O157:H7 str. TW14359 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_003079041.1 3150460 R 544404 CDS YP_003079042.1 254794205 8217753 complement(3151124..3152641) 1 NC_013008.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 3152641 purF 8217753 purF Escherichia coli O157:H7 str. TW14359 amidophosphoribosyltransferase YP_003079042.1 3151124 R 544404 CDS YP_003079043.1 254794206 8217754 complement(3152678..3153166) 1 NC_013008.1 membrane protein required for colicin V production; colicin V production protein 3153166 cvpA 8217754 cvpA Escherichia coli O157:H7 str. TW14359 colicin V production protein YP_003079043.1 3152678 R 544404 CDS YP_003079044.1 254794207 8217755 complement(3153698..3154360) 1 NC_013008.1 hypothetical protein 3154360 dedD 8217755 dedD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079044.1 3153698 R 544404 CDS YP_003079045.1 254794208 8217756 complement(3154350..3155618) 1 NC_013008.1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 3155618 folC 8217756 folC Escherichia coli O157:H7 str. TW14359 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_003079045.1 3154350 R 544404 CDS YP_003079046.1 254794209 8217757 complement(3155688..3156602) 1 NC_013008.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 3156602 accD 8217757 accD Escherichia coli O157:H7 str. TW14359 acetyl-CoA carboxylase subunit beta YP_003079046.1 3155688 R 544404 CDS YP_003079047.1 254794210 8217758 complement(3156758..3157417) 1 NC_013008.1 hypothetical protein 3157417 dedA 8217758 dedA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079047.1 3156758 R 544404 CDS YP_003079048.1 254794211 8217759 complement(3157500..3158312) 1 NC_013008.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 3158312 truA 8217759 truA Escherichia coli O157:H7 str. TW14359 tRNA pseudouridine synthase A YP_003079048.1 3157500 R 544404 CDS YP_003079049.1 254794212 8217760 complement(3158312..3159325) 1 NC_013008.1 semialdehyde dehydrogenase 3159325 usg 8217760 usg Escherichia coli O157:H7 str. TW14359 semialdehyde dehydrogenase YP_003079049.1 3158312 R 544404 CDS YP_003079050.1 254794213 8217761 complement(3159391..3160527) 1 NC_013008.1 erythronate-4-phosphate dehydrogenase 3160527 pdxB 8217761 pdxB Escherichia coli O157:H7 str. TW14359 erythronate-4-phosphate dehydrogenase YP_003079050.1 3159391 R 544404 CDS YP_003079051.1 254794214 8217762 3160626..3161621 1 NC_013008.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 3161621 flk 8217762 flk Escherichia coli O157:H7 str. TW14359 flagella biosynthesis regulator YP_003079051.1 3160626 D 544404 CDS YP_003079052.1 254794215 8217763 complement(3161618..3162796) 1 NC_013008.1 hypothetical protein 3162796 yfcJ 8217763 yfcJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079052.1 3161618 R 544404 CDS YP_003079053.1 254794216 8217764 complement(3163071..3164291) 1 NC_013008.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 3164291 fabB 8217764 fabB Escherichia coli O157:H7 str. TW14359 3-oxoacyl-ACP synthase YP_003079053.1 3163071 R 544404 CDS YP_003079054.1 254794217 8217765 3164450..3166456 1 NC_013008.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 3166456 mnmC 8217765 mnmC Escherichia coli O157:H7 str. TW14359 5-methylaminomethyl-2-thiouridine methyltransferase YP_003079054.1 3164450 D 544404 CDS YP_003079055.1 254794218 8217766 complement(3166577..3166855) 1 NC_013008.1 hypothetical protein 3166855 yfcL 8217766 yfcL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079055.1 3166577 R 544404 CDS YP_003079056.1 254794219 8217767 complement(3166889..3167437) 1 NC_013008.1 hypothetical protein 3167437 yfcM 8217767 yfcM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079056.1 3166889 R 544404 CDS YP_003079057.1 254794220 8217768 complement(3167437..3168246) 1 NC_013008.1 hypothetical protein 3168246 yfcA 8217768 yfcA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079057.1 3167437 R 544404 CDS YP_003079058.1 254794221 8217769 complement(3168246..3169070) 1 NC_013008.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 3169070 mepA 8217769 mepA Escherichia coli O157:H7 str. TW14359 penicillin-insensitive murein endopeptidase YP_003079058.1 3168246 R 544404 CDS YP_003079059.1 254794222 8217770 complement(3169074..3170159) 1 NC_013008.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3170159 aroC 8217770 aroC Escherichia coli O157:H7 str. TW14359 chorismate synthase YP_003079059.1 3169074 R 544404 CDS YP_003079060.1 254794223 8217771 complement(3170194..3171126) 1 NC_013008.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 3171126 prmB 8217771 prmB Escherichia coli O157:H7 str. TW14359 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_003079060.1 3170194 R 544404 CDS YP_003079061.1 254794224 8217772 3171292..3171843 1 NC_013008.1 hypothetical protein 3171843 yfcN 8217772 yfcN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079061.1 3171292 D 544404 CDS YP_003079062.1 254794225 8217773 complement(3172014..3172856) 1 NC_013008.1 hypothetical protein 3172856 8217773 ECSP_3207 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079062.1 3172014 R 544404 CDS YP_003079063.1 254794226 8217774 complement(3172858..3173379) 1 NC_013008.1 minor fimbrial subunit 3173379 8217774 ECSP_3208 Escherichia coli O157:H7 str. TW14359 minor fimbrial subunit YP_003079063.1 3172858 R 544404 CDS YP_003079064.1 254794227 8217775 complement(3173782..3174252) 1 NC_013008.1 minor fimbrial subunit 3174252 8217775 ECSP_3209 Escherichia coli O157:H7 str. TW14359 minor fimbrial subunit YP_003079064.1 3173782 R 544404 CDS YP_003079065.1 254794228 8217776 complement(3174249..3174749) 1 NC_013008.1 minor fimbrial subunit 3174749 8217776 ECSP_3210 Escherichia coli O157:H7 str. TW14359 minor fimbrial subunit YP_003079065.1 3174249 R 544404 CDS YP_003079066.1 254794229 8217777 complement(3174760..3175518) 1 NC_013008.1 periplasmic pilus chaperone 3175518 yfcS 8217777 yfcS Escherichia coli O157:H7 str. TW14359 periplasmic pilus chaperone YP_003079066.1 3174760 R 544404 CDS YP_003079067.1 254794230 8217778 complement(3175541..3178180) 1 NC_013008.1 fimbrial usher 3178180 yfcU 8217778 yfcU Escherichia coli O157:H7 str. TW14359 fimbrial usher YP_003079067.1 3175541 R 544404 CDS YP_003079068.1 254794231 8217779 complement(3178262..3178825) 1 NC_013008.1 fimbrial-like adhesin protein 3178825 yfcV 8217779 yfcV Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003079068.1 3178262 R 544404 CDS YP_003079069.1 254794232 8217780 complement(3179471..3179956) 1 NC_013008.1 phosphohistidine phosphatase 3179956 sixA 8217780 sixA Escherichia coli O157:H7 str. TW14359 phosphohistidine phosphatase YP_003079069.1 3179471 R 544404 CDS YP_003079070.1 254794233 8217781 complement(3180159..3182303) 1 NC_013008.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 3182303 fadJ 8217781 fadJ Escherichia coli O157:H7 str. TW14359 multifunctional fatty acid oxidation complex subunit alpha YP_003079070.1 3180159 R 544404 CDS YP_003079071.1 254794234 8217782 complement(3182303..3183613) 1 NC_013008.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 3183613 fadI 8217782 fadI Escherichia coli O157:H7 str. TW14359 3-ketoacyl-CoA thiolase YP_003079071.1 3182303 R 544404 CDS YP_003079072.1 254794235 8217783 complement(3183793..3184077) 1 NC_013008.1 hypothetical protein 3184077 yfcZ 8217783 yfcZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079072.1 3183793 R 544404 CDS YP_003079073.1 254794236 8217784 3184449..3185789 1 NC_013008.1 long-chain fatty acid outer membrane transporter 3185789 fadL 8217784 fadL Escherichia coli O157:H7 str. TW14359 long-chain fatty acid outer membrane transporter YP_003079073.1 3184449 D 544404 CDS YP_003079074.1 254794237 8217785 3186154..3187185 1 NC_013008.1 hypothetical protein 3187185 yfdF 8217785 yfdF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079074.1 3186154 D 544404 CDS YP_003079075.1 254794238 8217786 complement(3187580..3188335) 1 NC_013008.1 lipoprotein 3188335 vacJ 8217786 vacJ Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003079075.1 3187580 R 544404 CDS YP_003079076.1 254794239 8217787 3188629..3189561 1 NC_013008.1 inner membrane protein 3189561 yfdC 8217787 yfdC Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079076.1 3188629 D 544404 CDS YP_003079077.1 254794240 8217788 complement(3189783..3198158) 1 NC_013008.1 hypothetical protein 3198158 8217788 ECSP_3222 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079077.1 3189783 R 544404 CDS YP_003079078.1 254794241 8217789 complement(3198227..3199492) 1 NC_013008.1 hypothetical protein 3199492 8217789 ECSP_3223 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079078.1 3198227 R 544404 CDS YP_003079079.1 254794242 8217790 complement(3199503..3199796) 1 NC_013008.1 hypothetical protein 3199796 8217790 ECSP_3224 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079079.1 3199503 R 544404 CDS YP_003079080.1 254794243 8217791 complement(3199806..3200252) 1 NC_013008.1 hypothetical protein 3200252 8217791 ECSP_3225 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079080.1 3199806 R 544404 CDS YP_003079081.1 254794244 8217792 complement(3200255..3200911) 1 NC_013008.1 hypothetical protein 3200911 8217792 ECSP_3226 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079081.1 3200255 R 544404 CDS YP_003079082.1 254794245 8217793 complement(3201006..3201407) 1 NC_013008.1 hypothetical protein 3201407 8217793 ECSP_3227 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079082.1 3201006 R 544404 CDS YP_003079083.1 254794246 8217794 complement(3201835..3202569) 1 NC_013008.1 outer membrane protein Lom 3202569 lomW 8217794 lomW Escherichia coli O157:H7 str. TW14359 outer membrane protein Lom YP_003079083.1 3201835 R 544404 CDS YP_003079084.1 254794247 8217795 complement(3202660..3203277) 1 NC_013008.1 hypothetical protein 3203277 8217795 ECSP_3229 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079084.1 3202660 R 544404 CDS YP_003079085.1 254794248 8217796 complement(3203576..3204844) 1 NC_013008.1 hypothetical protein 3204844 8217796 ECSP_3230 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079085.1 3203576 R 544404 CDS YP_003079086.1 254794249 8217797 complement(3204841..3206544) 1 NC_013008.1 hypothetical protein 3206544 8217797 ECSP_3231 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079086.1 3204841 R 544404 CDS YP_003079087.1 254794250 8217798 complement(3206761..3207003) 1 NC_013008.1 hypothetical protein 3207003 8217798 ECSP_3232 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079087.1 3206761 R 544404 CDS YP_003079088.1 254794251 8217799 complement(3207088..3207357) 1 NC_013008.1 tail fiber protein of bacteriophage BP-933W 3207357 8217799 ECSP_3233 Escherichia coli O157:H7 str. TW14359 tail fiber protein of bacteriophage BP-933W YP_003079088.1 3207088 R 544404 CDS YP_003079089.1 254794252 8217800 complement(3207359..3209296) 1 NC_013008.1 tail fiber protein of bacteriophage BP-933W 3209296 8217800 ECSP_3234 Escherichia coli O157:H7 str. TW14359 tail fiber protein of bacteriophage BP-933W YP_003079089.1 3207359 R 544404 CDS YP_003079090.1 254794253 8217801 complement(3209293..3209943) 1 NC_013008.1 hypothetical protein 3209943 8217801 ECSP_3235 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079090.1 3209293 R 544404 CDS YP_003079091.1 254794254 8217802 complement(3210490..3210951) 1 NC_013008.1 hypothetical protein 3210951 8217802 ECSP_3236 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079091.1 3210490 R 544404 CDS YP_003079092.1 254794255 8217803 complement(3211001..3211390) 1 NC_013008.1 hypothetical protein 3211390 8217803 ECSP_3237 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079092.1 3211001 R 544404 CDS YP_003079093.1 254794256 8217804 complement(3211446..3212660) 1 NC_013008.1 hypothetical protein 3212660 8217804 ECSP_3238 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079093.1 3211446 R 544404 CDS YP_003079094.1 254794257 8217805 3213231..3213557 1 NC_013008.1 transposase 3213557 8217805 ECSP_3239 Escherichia coli O157:H7 str. TW14359 transposase YP_003079094.1 3213231 D 544404 CDS YP_003079095.1 254794258 8217806 3213554..3214444 1 NC_013008.1 transposase 3214444 8217806 ECSP_3240 Escherichia coli O157:H7 str. TW14359 transposase YP_003079095.1 3213554 D 544404 CDS YP_003079096.1 254794259 8217807 complement(3214447..3215004) 1 NC_013008.1 hypothetical protein 3215004 8217807 ECSP_3241 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079096.1 3214447 R 544404 CDS YP_003079097.1 254794260 8217808 complement(3215162..3217306) 1 NC_013008.1 portal protein of bacteriophage BP-933W 3217306 8217808 ECSP_3242 Escherichia coli O157:H7 str. TW14359 portal protein of bacteriophage BP-933W YP_003079097.1 3215162 R 544404 CDS YP_003079098.1 254794261 8217809 complement(3217306..3219012) 1 NC_013008.1 terminase large subunit of bacteriophage BP-933W 3219012 8217809 ECSP_3243 Escherichia coli O157:H7 str. TW14359 terminase large subunit of bacteriophage BP-933W YP_003079098.1 3217306 R 544404 CDS YP_003079099.1 254794262 8217810 complement(3218993..3219799) 1 NC_013008.1 terminase small subunit of bacteriophage BP-933W 3219799 8217810 ECSP_3244 Escherichia coli O157:H7 str. TW14359 terminase small subunit of bacteriophage BP-933W YP_003079099.1 3218993 R 544404 CDS YP_003079100.1 254794263 8217811 3220208..3220501 1 NC_013008.1 Bor protein 3220501 borW 8217811 borW Escherichia coli O157:H7 str. TW14359 Bor protein YP_003079100.1 3220208 D 544404 CDS YP_003079101.1 254794264 8217812 complement(3220533..3220997) 1 NC_013008.1 lysis protein Rz 3220997 rz 8217812 rz Escherichia coli O157:H7 str. TW14359 lysis protein Rz YP_003079101.1 3220533 R 544404 CDS YP_003079102.1 254794265 8217813 complement(3221005..3221139) 1 NC_013008.1 hypothetical protein 3221139 8217813 ECSP_3247 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079102.1 3221005 R 544404 CDS YP_003079103.1 254794266 8217814 complement(3221154..3221723) 1 NC_013008.1 antirepressor protein Ant 3221723 ant 8217814 ant Escherichia coli O157:H7 str. TW14359 antirepressor protein Ant YP_003079103.1 3221154 R 544404 CDS YP_003079104.1 254794267 8217815 complement(3221997..3222530) 1 NC_013008.1 endolysin R 3222530 r 8217815 r Escherichia coli O157:H7 str. TW14359 endolysin R YP_003079104.1 3221997 R 544404 CDS YP_003079105.1 254794268 8217816 complement(3222827..3223273) 1 NC_013008.1 hypothetical protein 3223273 8217816 ECSP_3250 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079105.1 3222827 R 544404 CDS YP_003079106.1 254794269 8217817 complement(3223454..3225391) 1 NC_013008.1 hypothetical protein 3225391 8217817 ECSP_3251 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079106.1 3223454 R 544404 CDS YP_003079107.1 254794270 8217818 complement(3225878..3226147) 1 NC_013008.1 shiga toxin II subunit B 3226147 stx2B 8217818 stx2B Escherichia coli O157:H7 str. TW14359 shiga toxin II subunit B YP_003079107.1 3225878 R 544404 CDS YP_003079108.1 254794271 8217819 complement(3226159..3227118) 1 NC_013008.1 shiga toxin II subunit A 3227118 stx2A2 8217819 stx2A2 Escherichia coli O157:H7 str. TW14359 shiga toxin II subunit A YP_003079108.1 3226159 R 544404 CDS YP_003079109.1 254794272 8217823 complement(3227900..3228334) 1 NC_013008.1 antitermination protein Q of bacteriophage BP-933W 3228334 q 8217823 q Escherichia coli O157:H7 str. TW14359 antitermination protein Q of bacteriophage BP-933W YP_003079109.1 3227900 R 544404 CDS YP_003079110.1 254794273 8217824 complement(3228518..3229123) 1 NC_013008.1 NinG protein 3229123 ninG 8217824 ninG Escherichia coli O157:H7 str. TW14359 NinG protein YP_003079110.1 3228518 R 544404 CDS YP_003079111.1 254794274 8217825 complement(3229123..3229845) 1 NC_013008.1 DNA-binding protein Roi 3229845 roi 8217825 roi Escherichia coli O157:H7 str. TW14359 DNA-binding protein Roi YP_003079111.1 3229123 R 544404 CDS YP_003079112.1 254794275 8217826 complement(3230007..3230408) 1 NC_013008.1 hypothetical protein 3230408 8217826 ECSP_3260 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079112.1 3230007 R 544404 CDS YP_003079113.1 254794276 8217827 complement(3230483..3231157) 1 NC_013008.1 antirepressor protein 3231157 8217827 ECSP_3261 Escherichia coli O157:H7 str. TW14359 antirepressor protein YP_003079113.1 3230483 R 544404 CDS YP_003079114.1 254794277 8217828 complement(3231414..3231608) 1 NC_013008.1 NinE protein 3231608 ninE 8217828 ninE Escherichia coli O157:H7 str. TW14359 NinE protein YP_003079114.1 3231414 R 544404 CDS YP_003079115.1 254794278 8217829 complement(3231605..3232132) 1 NC_013008.1 DNA N-6-adenine-methyltransferase of bacteriophage BP-933W 3232132 8217829 ECSP_3263 Escherichia coli O157:H7 str. TW14359 DNA N-6-adenine-methyltransferase of bacteriophage BP-933W YP_003079115.1 3231605 R 544404 CDS YP_003079116.1 254794279 8217830 complement(3232129..3232731) 1 NC_013008.1 endonuclease 3232731 8217830 ECSP_3264 Escherichia coli O157:H7 str. TW14359 endonuclease YP_003079116.1 3232129 R 544404 CDS YP_003079117.1 254794280 8217831 complement(3232724..3233140) 1 NC_013008.1 NinB protein 3233140 ninB 8217831 ninB Escherichia coli O157:H7 str. TW14359 NinB protein YP_003079117.1 3232724 R 544404 CDS YP_003079118.1 254794281 8217832 complement(3233662..3233940) 1 NC_013008.1 hypothetical protein 3233940 8217832 ECSP_3266 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079118.1 3233662 R 544404 CDS YP_003079119.1 254794282 8217833 complement(3234011..3234301) 1 NC_013008.1 Ren protein 3234301 ren 8217833 ren Escherichia coli O157:H7 str. TW14359 Ren protein YP_003079119.1 3234011 R 544404 CDS YP_003079120.1 254794283 8217834 complement(3234298..3234999) 1 NC_013008.1 replication protein P of bacteriophage BP-933W 3234999 p 8217834 p Escherichia coli O157:H7 str. TW14359 replication protein P of bacteriophage BP-933W YP_003079120.1 3234298 R 544404 CDS YP_003079121.1 254794284 8217835 complement(3234996..3235934) 1 NC_013008.1 replication protein O 3235934 o 8217835 o Escherichia coli O157:H7 str. TW14359 replication protein O YP_003079121.1 3234996 R 544404 CDS YP_003079122.1 254794285 8217836 complement(3235967..3236263) 1 NC_013008.1 regulatory protein CII of bacteriophage BP-933W 3236263 cII 8217836 cII Escherichia coli O157:H7 str. TW14359 regulatory protein CII of bacteriophage BP-933W YP_003079122.1 3235967 R 544404 CDS YP_003079123.1 254794286 8217837 complement(3236402..3236629) 1 NC_013008.1 regulatory protein Cro 3236629 cro 8217837 cro Escherichia coli O157:H7 str. TW14359 regulatory protein Cro YP_003079123.1 3236402 R 544404 CDS YP_003079124.1 254794287 8217838 3236708..3237415 1 NC_013008.1 repressor protein CI 3237415 cI 8217838 cI Escherichia coli O157:H7 str. TW14359 repressor protein CI YP_003079124.1 3236708 D 544404 CDS YP_003079125.1 254794288 8217839 3237476..3237817 1 NC_013008.1 hypothetical protein 3237817 8217839 ECSP_3273 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079125.1 3237476 D 544404 CDS YP_003079126.1 254794289 8217840 3237885..3238346 1 NC_013008.1 hypothetical protein 3238346 8217840 ECSP_3274 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079126.1 3237885 D 544404 CDS YP_003079127.1 254794290 8217841 3238340..3239386 1 NC_013008.1 serine/threonine kinase encoded by bacteriophage BP-933W 3239386 8217841 ECSP_3275 Escherichia coli O157:H7 str. TW14359 serine/threonine kinase encoded by bacteriophage BP-933W YP_003079127.1 3238340 D 544404 CDS YP_003079128.1 254794291 8217842 3239389..3239553 1 NC_013008.1 hypothetical protein 3239553 8217842 ECSP_3276 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079128.1 3239389 D 544404 CDS YP_003079129.1 254794292 8217843 3240042..3240425 1 NC_013008.1 antitermination protein N of bacteriophage BP-933W 3240425 n 8217843 n Escherichia coli O157:H7 str. TW14359 antitermination protein N of bacteriophage BP-933W YP_003079129.1 3240042 D 544404 CDS YP_003079130.1 254794293 8217844 3240484..3240954 1 NC_013008.1 hypothetical protein 3240954 8217844 ECSP_3278 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079130.1 3240484 D 544404 CDS YP_003079131.1 254794294 8217845 3241105..3241473 1 NC_013008.1 single-stranded DNA binding protein 3241473 ssbW 8217845 ssbW Escherichia coli O157:H7 str. TW14359 single-stranded DNA binding protein YP_003079131.1 3241105 D 544404 CDS YP_003079132.1 254794295 8217846 3241553..3241843 1 NC_013008.1 Kil protein of bacteriphage BP-933W 3241843 kilW 8217846 kilW Escherichia coli O157:H7 str. TW14359 Kil protein of bacteriphage BP-933W YP_003079132.1 3241553 D 544404 CDS YP_003079133.1 254794296 8217847 3241898..3242194 1 NC_013008.1 host-nuclease inhibitor protein Gam 3242194 gamW 8217847 gamW Escherichia coli O157:H7 str. TW14359 host-nuclease inhibitor protein Gam YP_003079133.1 3241898 D 544404 CDS YP_003079134.1 254794297 8217848 3242200..3242985 1 NC_013008.1 Bet recombination protein 3242985 betW 8217848 betW Escherichia coli O157:H7 str. TW14359 Bet recombination protein YP_003079134.1 3242200 D 544404 CDS YP_003079135.1 254794298 8217849 3242982..3243662 1 NC_013008.1 exonuclease 3243662 exoW 8217849 exoW Escherichia coli O157:H7 str. TW14359 exonuclease YP_003079135.1 3242982 D 544404 CDS YP_003079136.1 254794299 8217850 3244016..3244297 1 NC_013008.1 hypothetical protein 3244297 8217850 ECSP_3284 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079136.1 3244016 D 544404 CDS YP_003079137.1 254794300 8217851 3244614..3245561 1 NC_013008.1 hypothetical protein 3245561 8217851 ECSP_3285 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079137.1 3244614 D 544404 CDS YP_003079138.1 254794301 8217852 3245563..3246069 1 NC_013008.1 heme binding virulence factor 3246069 8217852 ECSP_3286 Escherichia coli O157:H7 str. TW14359 heme binding virulence factor YP_003079138.1 3245563 D 544404 CDS YP_003079139.1 254794302 8217853 complement(3246131..3246427) 1 NC_013008.1 hypothetical protein 3246427 8217853 ECSP_3287 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079139.1 3246131 R 544404 CDS YP_003079140.1 254794303 8217854 3246466..3246753 1 NC_013008.1 hypothetical protein 3246753 8217854 ECSP_3288 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079140.1 3246466 D 544404 CDS YP_003079141.1 254794304 8217855 3246757..3247374 1 NC_013008.1 hypothetical protein 3247374 8217855 ECSP_3289 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079141.1 3246757 D 544404 CDS YP_003079142.1 254794305 8217856 3247651..3247749 1 NC_013008.1 hypothetical protein 3247749 8217856 ECSP_3290 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079142.1 3247651 D 544404 CDS YP_003079143.1 254794306 8217857 3247984..3248637 1 NC_013008.1 phage anti-repressor protein AntB 3248637 antB 8217857 antB Escherichia coli O157:H7 str. TW14359 phage anti-repressor protein AntB YP_003079143.1 3247984 D 544404 CDS YP_003079144.1 254794307 8217858 3248680..3248847 1 NC_013008.1 hypothetical protein 3248847 8217858 ECSP_3292 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079144.1 3248680 D 544404 CDS YP_003079145.1 254794308 8217859 3249074..3249700 1 NC_013008.1 adenine methylase 3249700 8217859 ECSP_3293 Escherichia coli O157:H7 str. TW14359 adenine methylase YP_003079145.1 3249074 D 544404 CDS YP_003079146.1 254794309 8217860 3249660..3249872 1 NC_013008.1 hypothetical protein 3249872 8217860 ECSP_3294 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079146.1 3249660 D 544404 CDS YP_003079147.1 254794310 8217861 3249908..3250285 1 NC_013008.1 hypothetical protein 3250285 8217861 ECSP_3295 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079147.1 3249908 D 544404 CDS YP_003079148.1 254794311 8217862 3250364..3250546 1 NC_013008.1 hypothetical protein 3250546 8217862 ECSP_3296 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079148.1 3250364 D 544404 CDS YP_003079149.1 254794312 8217863 complement(3250530..3251699) 1 NC_013008.1 integrase 3251699 intW 8217863 intW Escherichia coli O157:H7 str. TW14359 integrase YP_003079149.1 3250530 R 544404 CDS YP_003079150.1 254794313 8217865 3252131..3253288 1 NC_013008.1 CPS-53 (KpLE1) prophage; prophage CPS-53 integrase 3253288 intS 8217865 intS Escherichia coli O157:H7 str. TW14359 CPS-53 (KpLE1) prophage; prophage CPS-53 integrase YP_003079150.1 3252131 D 544404 CDS YP_003079151.1 254794314 8217866 complement(3253463..3254599) 1 NC_013008.1 prophage DNA injection protein 3254599 8217866 ECSP_3300 Escherichia coli O157:H7 str. TW14359 prophage DNA injection protein YP_003079151.1 3253463 R 544404 CDS YP_003079152.1 254794315 8217867 complement(3254609..3255289) 1 NC_013008.1 prophage DNA injection protein 3255289 8217867 ECSP_3301 Escherichia coli O157:H7 str. TW14359 prophage DNA injection protein YP_003079152.1 3254609 R 544404 CDS YP_003079153.1 254794316 8217868 complement(3255276..3255743) 1 NC_013008.1 hypothetical protein 3255743 8217868 ECSP_3302 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079153.1 3255276 R 544404 CDS YP_003079154.1 254794317 8217869 complement(3255743..3256312) 1 NC_013008.1 hypothetical protein 3256312 8217869 ECSP_3303 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079154.1 3255743 R 544404 CDS YP_003079155.1 254794318 8217870 3256295..3256990 1 NC_013008.1 hypothetical protein 3256990 8217870 ECSP_3304 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079155.1 3256295 D 544404 CDS YP_003079156.1 254794319 8217871 complement(3257170..3257313) 1 NC_013008.1 hypothetical protein 3257313 8217871 ECSP_3305 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079156.1 3257170 R 544404 CDS YP_003079157.1 254794320 8217872 complement(3257660..3259072) 1 NC_013008.1 hypothetical protein 3259072 8217872 ECSP_3306 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079157.1 3257660 R 544404 CDS YP_003079158.1 254794321 8217873 complement(3259259..3259435) 1 NC_013008.1 hypothetical protein 3259435 8217873 ECSP_3307 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079158.1 3259259 R 544404 CDS YP_003079159.1 254794322 8217874 3259738..3260364 1 NC_013008.1 resolvase 3260364 8217874 ECSP_3308 Escherichia coli O157:H7 str. TW14359 resolvase YP_003079159.1 3259738 D 544404 CDS YP_003079160.1 254794323 8217875 3260730..3260882 1 NC_013008.1 hypothetical protein 3260882 8217875 ECSP_3309 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079160.1 3260730 D 544404 CDS YP_003079161.1 254794324 8217876 complement(3260962..3262209) 1 NC_013008.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 3262209 lacY 8217876 lacY Escherichia coli O157:H7 str. TW14359 galactoside permease YP_003079161.1 3260962 R 544404 CDS YP_003079162.1 254794325 8217877 complement(3262281..3263195) 1 NC_013008.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 3263195 cscK 8217877 cscK Escherichia coli O157:H7 str. TW14359 aminoimidazole riboside kinase YP_003079162.1 3262281 R 544404 CDS YP_003079163.1 254794326 8217878 3263411..3264844 1 NC_013008.1 sucrose 6-phosphate hydrolase 3264844 cscA 8217878 cscA Escherichia coli O157:H7 str. TW14359 sucrose 6-phosphate hydrolase YP_003079163.1 3263411 D 544404 CDS YP_003079164.1 254794327 8217879 complement(3264852..3265847) 1 NC_013008.1 csc-specific repressor 3265847 cscR 8217879 cscR Escherichia coli O157:H7 str. TW14359 csc-specific repressor YP_003079164.1 3264852 R 544404 CDS YP_003079165.1 254794328 8217881 3266326..3267654 1 NC_013008.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 3267654 dsdA 8217881 dsdA Escherichia coli O157:H7 str. TW14359 D-serine dehydratase YP_003079165.1 3266326 D 544404 CDS YP_003079166.1 254794329 8217882 complement(3267762..3269300) 1 NC_013008.1 multidrug efflux system 3269300 emrY 8217882 emrY Escherichia coli O157:H7 str. TW14359 multidrug efflux system YP_003079166.1 3267762 R 544404 CDS YP_003079167.1 254794330 8217883 complement(3269300..3270463) 1 NC_013008.1 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 3270463 emrK 8217883 emrK Escherichia coli O157:H7 str. TW14359 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component YP_003079167.1 3269300 R 544404 CDS YP_003079168.1 254794331 8217884 3270879..3271493 1 NC_013008.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 3271493 evgA 8217884 evgA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator EvgA YP_003079168.1 3270879 D 544404 CDS YP_003079169.1 254794332 8217885 3271498..3275091 1 NC_013008.1 hybrid sensory histidine kinase in two-component regulatory system with EvgA 3275091 evgS 8217885 evgS Escherichia coli O157:H7 str. TW14359 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_003079169.1 3271498 D 544404 CDS YP_003079170.1 254794333 8217887 complement(3276362..3277306) 1 NC_013008.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 3277306 yfdV 8217887 yfdV Escherichia coli O157:H7 str. TW14359 transporter YfdV YP_003079170.1 3276362 R 544404 CDS YP_003079171.1 254794334 8217888 complement(3277376..3279070) 1 NC_013008.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 3279070 oxc 8217888 oxc Escherichia coli O157:H7 str. TW14359 oxalyl-CoA decarboxylase YP_003079171.1 3277376 R 544404 CDS YP_003079172.1 254794335 8217889 complement(3279124..3280374) 1 NC_013008.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 3280374 frc 8217889 frc Escherichia coli O157:H7 str. TW14359 formyl-coenzyme A transferase YP_003079172.1 3279124 R 544404 CDS YP_003079173.1 254794336 8217890 complement(3280887..3281522) 1 NC_013008.1 hypothetical protein 3281522 yfdX 8217890 yfdX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079173.1 3280887 R 544404 CDS YP_003079174.1 254794337 8217891 3281818..3282093 1 NC_013008.1 lipoprotein involved in colanic acid biosynthesis 3282093 ypdI 8217891 ypdI Escherichia coli O157:H7 str. TW14359 lipoprotein involved in colanic acid biosynthesis YP_003079174.1 3281818 D 544404 CDS YP_003079175.1 254794338 8217892 complement(3282170..3282412) 1 NC_013008.1 inner membrane protein 3282412 yfdY 8217892 yfdY Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079175.1 3282170 R 544404 CDS YP_003079176.1 254794339 8217893 3282765..3283685 1 NC_013008.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 3283685 lpxP 8217893 lpxP Escherichia coli O157:H7 str. TW14359 lipid A biosynthesis palmitoleoyl acyltransferase YP_003079176.1 3282765 D 544404 CDS YP_003079177.1 254794340 8217894 3283996..3284112 1 NC_013008.1 hypothetical protein 3284112 8217894 ECSP_3328 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079177.1 3283996 D 544404 CDS YP_003079178.1 254794341 8217895 complement(3284177..3285415) 1 NC_013008.1 aminotransferase 3285415 yfdZ 8217895 yfdZ Escherichia coli O157:H7 str. TW14359 aminotransferase YP_003079178.1 3284177 R 544404 CDS YP_003079179.1 254794342 8217896 3285792..3287489 1 NC_013008.1 sensory kinase in two-component system with YpdB 3287489 ypdA 8217896 ypdA Escherichia coli O157:H7 str. TW14359 sensory kinase in two-component system with YpdB YP_003079179.1 3285792 D 544404 CDS YP_003079180.1 254794343 8217897 3287504..3288238 1 NC_013008.1 response regulator in two-component system withYpdA 3288238 ypdB 8217897 ypdB Escherichia coli O157:H7 str. TW14359 response regulator in two-component system withYpdA YP_003079180.1 3287504 D 544404 CDS YP_003079181.1 254794344 8217898 3288251..3289108 1 NC_013008.1 DNA-binding protein 3289108 ypdC 8217898 ypdC Escherichia coli O157:H7 str. TW14359 DNA-binding protein YP_003079181.1 3288251 D 544404 CDS YP_003079182.1 254794345 8217899 complement(3289111..3291606) 1 NC_013008.1 fused PTS enzymes: Hpr component, enzyme I component, enzyme IIA component 3291606 8217899 ECSP_3333 Escherichia coli O157:H7 str. TW14359 fused PTS enzymes: Hpr component, enzyme I component, enzyme IIA component YP_003079182.1 3289111 R 544404 CDS YP_003079183.1 254794346 8217900 complement(3291631..3292668) 1 NC_013008.1 metalloprotein; exoaminopeptidase 3292668 ypdE 8217900 ypdE Escherichia coli O157:H7 str. TW14359 exoaminopeptidase YP_003079183.1 3291631 R 544404 CDS YP_003079184.1 254794347 8217901 complement(3292668..3293753) 1 NC_013008.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 3293753 ypdF 8217901 ypdF Escherichia coli O157:H7 str. TW14359 aminopeptidase YP_003079184.1 3292668 R 544404 CDS YP_003079185.1 254794348 8217902 complement(3293768..3295015) 1 NC_013008.1 enzyme IIC component of PTS 3295015 8217902 ECSP_3336 Escherichia coli O157:H7 str. TW14359 enzyme IIC component of PTS YP_003079185.1 3293768 R 544404 CDS YP_003079186.1 254794349 8217903 complement(3295037..3295363) 1 NC_013008.1 enzyme IIB component of PTS 3295363 8217903 ECSP_3337 Escherichia coli O157:H7 str. TW14359 enzyme IIB component of PTS YP_003079186.1 3295037 R 544404 CDS YP_003079187.1 254794350 8217904 complement(3295582..3296547) 1 NC_013008.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 3296547 glk 8217904 glk Escherichia coli O157:H7 str. TW14359 glucokinase YP_003079187.1 3295582 R 544404 CDS YP_003079188.1 254794351 8217905 3296751..3298007 1 NC_013008.1 hypothetical protein 3298007 yfeO 8217905 yfeO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079188.1 3296751 D 544404 CDS YP_003079189.1 254794352 8217906 3298122..3298448 1 NC_013008.1 hypothetical protein 3298448 ypeC 8217906 ypeC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079189.1 3298122 D 544404 CDS YP_003079190.1 254794353 8217907 complement(3298588..3299826) 1 NC_013008.1 manganese transport protein MntH 3299826 mntH 8217907 mntH Escherichia coli O157:H7 str. TW14359 manganese transport protein MntH YP_003079190.1 3298588 R 544404 CDS YP_003079191.1 254794354 8217908 3300162..3301364 1 NC_013008.1 nucleoside (except guanosine) transporter 3301364 nupC 8217908 nupC Escherichia coli O157:H7 str. TW14359 nucleoside (except guanosine) transporter YP_003079191.1 3300162 D 544404 CDS YP_003079192.1 254794355 8217909 complement(3301414..3303603) 1 NC_013008.1 diguanylate cyclase 3303603 yfeA 8217909 yfeA Escherichia coli O157:H7 str. TW14359 diguanylate cyclase YP_003079192.1 3301414 R 544404 CDS YP_003079193.1 254794356 8217912 3304237..3304581 1 NC_013008.1 DNA-binding transcriptional regulator 3304581 yfeC 8217912 yfeC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079193.1 3304237 D 544404 CDS YP_003079194.1 254794357 8217913 3304583..3304975 1 NC_013008.1 DNA-binding transcriptional regulator 3304975 yfeD 8217913 yfeD Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079194.1 3304583 D 544404 CDS YP_003079195.1 254794358 8217914 complement(3305015..3306223) 1 NC_013008.1 virulence protein 3306223 8217914 ECSP_3348 Escherichia coli O157:H7 str. TW14359 virulence protein YP_003079195.1 3305015 R 544404 CDS YP_003079196.1 254794359 8217915 3306246..3306773 1 NC_013008.1 transposase IS200 like protein 3306773 8217915 ECSP_3349 Escherichia coli O157:H7 str. TW14359 transposase IS200 like protein YP_003079196.1 3306246 D 544404 CDS YP_003079197.1 254794360 8217916 complement(3306774..3308189) 1 NC_013008.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 3308189 gltX 8217916 gltX Escherichia coli O157:H7 str. TW14359 glutamyl-tRNA synthetase YP_003079197.1 3306774 R 544404 CDS YP_003079198.1 254794361 8217921 3308965..3309306 1 NC_013008.1 hypothetical protein 3309306 8217921 ECSP_3355 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079198.1 3308965 D 544404 CDS YP_003079199.1 254794362 8217922 complement(3309297..3310223) 1 NC_013008.1 LysR family transcriptional regulator 3310223 8217922 ECSP_3356 Escherichia coli O157:H7 str. TW14359 LysR family transcriptional regulator YP_003079199.1 3309297 R 544404 CDS YP_003079200.1 254794363 8217923 3310313..3311311 1 NC_013008.1 inner membrane protein 3311311 yfeH 8217923 yfeH Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079200.1 3310313 D 544404 CDS YP_003079201.1 254794364 8217924 complement(3311308..3311526) 1 NC_013008.1 hypothetical protein 3311526 ypeB 8217924 ypeB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079201.1 3311308 R 544404 CDS YP_003079202.1 254794365 8217925 complement(3311528..3313543) 1 NC_013008.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 3313543 ligA 8217925 ligA Escherichia coli O157:H7 str. TW14359 NAD-dependent DNA ligase LigA YP_003079202.1 3311528 R 544404 CDS YP_003079203.1 254794366 8217926 complement(3313614..3314612) 1 NC_013008.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 3314612 zipA 8217926 zipA Escherichia coli O157:H7 str. TW14359 cell division protein ZipA YP_003079203.1 3313614 R 544404 CDS YP_003079204.1 254794367 8217927 3314842..3315603 1 NC_013008.1 role in sulfur assimilation; sulfate transport protein CysZ 3315603 cysZ 8217927 cysZ Escherichia coli O157:H7 str. TW14359 sulfate transport protein CysZ YP_003079204.1 3314842 D 544404 CDS YP_003079205.1 254794368 8217928 3315788..3316759 1 NC_013008.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 3316759 cysK 8217928 cysK Escherichia coli O157:H7 str. TW14359 cysteine synthase A YP_003079205.1 3315788 D 544404 CDS YP_003079206.1 254794369 8217929 3317143..3317400 1 NC_013008.1 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 3317400 ptsH 8217929 ptsH Escherichia coli O157:H7 str. TW14359 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr YP_003079206.1 3317143 D 544404 CDS YP_003079207.1 254794370 8217930 3317445..3319172 1 NC_013008.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 3319172 ptsI 8217930 ptsI Escherichia coli O157:H7 str. TW14359 phosphoenolpyruvate-protein phosphotransferase YP_003079207.1 3317445 D 544404 CDS YP_003079208.1 254794371 8217931 3319213..3319722 1 NC_013008.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 3319722 crr 8217931 crr Escherichia coli O157:H7 str. TW14359 PTS system glucose-specific transporter subunit YP_003079208.1 3319213 D 544404 CDS YP_003079209.1 254794372 8217932 complement(3319765..3320616) 1 NC_013008.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 3320616 pdxK 8217932 pdxK Escherichia coli O157:H7 str. TW14359 pyridoxal kinase YP_003079209.1 3319765 R 544404 CDS YP_003079210.1 254794373 8217933 3320721..3321053 1 NC_013008.1 hypothetical protein 3321053 yfeK 8217933 yfeK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079210.1 3320721 D 544404 CDS YP_003079211.1 254794374 8217934 complement(3321091..3322002) 1 NC_013008.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 3322002 cysM 8217934 cysM Escherichia coli O157:H7 str. TW14359 cysteine synthase B YP_003079211.1 3321091 R 544404 CDS YP_003079212.1 254794375 8217935 complement(3322136..3323233) 1 NC_013008.1 sulfate/thiosulfate transporter subunit 3323233 cysA 8217935 cysA Escherichia coli O157:H7 str. TW14359 sulfate/thiosulfate transporter subunit YP_003079212.1 3322136 R 544404 CDS YP_003079213.1 254794376 8217936 complement(3323223..3324098) 1 NC_013008.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 3324098 cysW 8217936 cysW Escherichia coli O157:H7 str. TW14359 sulfate/thiosulfate transporter permease subunit YP_003079213.1 3323223 R 544404 CDS YP_003079214.1 254794377 8217937 complement(3324098..3324931) 1 NC_013008.1 sulfate/thiosulfate transporter subunit 3324931 cysU 8217937 cysU Escherichia coli O157:H7 str. TW14359 sulfate/thiosulfate transporter subunit YP_003079214.1 3324098 R 544404 CDS YP_003079215.1 254794378 8217938 complement(3324931..3325947) 1 NC_013008.1 thiosulfate transporter subunit 3325947 cysP 8217938 cysP Escherichia coli O157:H7 str. TW14359 thiosulfate transporter subunit YP_003079215.1 3324931 R 544404 CDS YP_003079216.1 254794379 8217939 complement(3326105..3326896) 1 NC_013008.1 short chain dehydrogenase 3326896 ucpA 8217939 ucpA Escherichia coli O157:H7 str. TW14359 short chain dehydrogenase YP_003079216.1 3326105 R 544404 CDS YP_003079217.1 254794380 8217940 complement(3327025..3327882) 1 NC_013008.1 DNA-binding transcriptional regulator 3327882 yfeT 8217940 yfeT Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079217.1 3327025 R 544404 CDS YP_003079218.1 254794381 8217941 3328046..3328942 1 NC_013008.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 3328942 murQ 8217941 murQ Escherichia coli O157:H7 str. TW14359 N-acetylmuramic acid-6-phosphate etherase YP_003079218.1 3328046 D 544404 CDS YP_003079219.1 254794382 8217942 3328946..3330370 1 NC_013008.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 3330370 murP 8217942 murP Escherichia coli O157:H7 str. TW14359 PTS system N-acetylmuramic acid transporter subunits EIIBC YP_003079219.1 3328946 D 544404 CDS YP_003079220.1 254794383 8217943 3330375..3331679 1 NC_013008.1 hypothetical protein 3331679 yfeW 8217943 yfeW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079220.1 3330375 D 544404 CDS YP_003079221.1 254794384 8217944 complement(3331737..3332636) 1 NC_013008.1 hypothetical protein 3332636 yfeX 8217944 yfeX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079221.1 3331737 R 544404 CDS YP_003079222.1 254794385 8217945 complement(3332732..3333307) 1 NC_013008.1 hypothetical protein 3333307 yfeY 8217945 yfeY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079222.1 3332732 R 544404 CDS YP_003079223.1 254794386 8217946 complement(3333368..3333817) 1 NC_013008.1 inner membrane protein 3333817 yfeZ 8217946 yfeZ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079223.1 3333368 R 544404 CDS YP_003079224.1 254794387 8217947 complement(3333804..3334229) 1 NC_013008.1 acetyltransferase 3334229 ypeA 8217947 ypeA Escherichia coli O157:H7 str. TW14359 acetyltransferase YP_003079224.1 3333804 R 544404 CDS YP_003079225.1 254794388 8217948 3334443..3335312 1 NC_013008.1 N-acetylmuramoyl-l-alanine amidase I 3335312 amiA 8217948 amiA Escherichia coli O157:H7 str. TW14359 N-acetylmuramoyl-l-alanine amidase I YP_003079225.1 3334443 D 544404 CDS YP_003079226.1 254794389 8217949 3335316..3336215 1 NC_013008.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 3336215 hemF 8217949 hemF Escherichia coli O157:H7 str. TW14359 coproporphyrinogen III oxidase YP_003079226.1 3335316 D 544404 CDS YP_003079227.1 254794390 8217950 complement(3336221..3337273) 1 NC_013008.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 3337273 yfeG 8217950 yfeG Escherichia coli O157:H7 str. TW14359 transcriptional regulator EutR YP_003079227.1 3336221 R 544404 CDS YP_003079228.1 254794391 8217951 complement(3337319..3337819) 1 NC_013008.1 carboxysome structural protein with role in ethanolamine utilization 3337819 8217951 ECSP_3385 Escherichia coli O157:H7 str. TW14359 carboxysome structural protein with role in ethanolamine utilization YP_003079228.1 3337319 R 544404 CDS YP_003079229.1 254794392 8217952 complement(3337832..3338491) 1 NC_013008.1 carboxysome structural protein with role in ethanolamine utilization 3338491 8217952 ECSP_3386 Escherichia coli O157:H7 str. TW14359 carboxysome structural protein with role in ethanolamine utilization YP_003079229.1 3337832 R 544404 CDS YP_003079230.1 254794393 8217953 complement(3338501..3339388) 1 NC_013008.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 3339388 eutC 8217953 eutC Escherichia coli O157:H7 str. TW14359 ethanolamine ammonia-lyase small subunit YP_003079230.1 3338501 R 544404 CDS YP_003079231.1 254794394 8217954 complement(3339409..3340770) 1 NC_013008.1 ethanolamine ammonia-lyase, large subunit, heavy chain 3340770 eutB 8217954 eutB Escherichia coli O157:H7 str. TW14359 ethanolamine ammonia-lyase, large subunit, heavy chain YP_003079231.1 3339409 R 544404 CDS YP_003079232.1 254794395 8217955 complement(3340782..3342185) 1 NC_013008.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 3342185 eutA 8217955 eutA Escherichia coli O157:H7 str. TW14359 reactivating factor for ethanolamine ammonia lyase YP_003079232.1 3340782 R 544404 CDS YP_003079233.1 254794396 8217956 complement(3342182..3343408) 1 NC_013008.1 inner membrane protein 3343408 eutH 8217956 eutH Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079233.1 3342182 R 544404 CDS YP_003079234.1 254794397 8217957 complement(3343508..3344695) 1 NC_013008.1 alcohol dehydrogenase in ethanolamine utilization 3344695 eutG 8217957 eutG Escherichia coli O157:H7 str. TW14359 alcohol dehydrogenase in ethanolamine utilization YP_003079234.1 3343508 R 544404 CDS YP_003079235.1 254794398 8217958 complement(3344685..3345521) 1 NC_013008.1 chaperonin, ethanolamine utilization protein 3345521 eutJ 8217958 eutJ Escherichia coli O157:H7 str. TW14359 chaperonin, ethanolamine utilization protein YP_003079235.1 3344685 R 544404 CDS YP_003079236.1 254794399 8217959 complement(3345532..3346935) 1 NC_013008.1 aldehyde dehydrogenase, ethanolamine utilization protein 3346935 eutE 8217959 eutE Escherichia coli O157:H7 str. TW14359 aldehyde dehydrogenase, ethanolamine utilization protein YP_003079236.1 3345532 R 544404 CDS YP_003079237.1 254794400 8217960 complement(3346947..3347234) 1 NC_013008.1 carboxysome structural protein, ethanolamine utilization protein 3347234 cchB 8217960 cchB Escherichia coli O157:H7 str. TW14359 carboxysome structural protein, ethanolamine utilization protein YP_003079237.1 3346947 R 544404 CDS YP_003079238.1 254794401 8217961 complement(3347341..3347634) 1 NC_013008.1 carboxysome structural protein, ethanolamine utilization protein 3347634 cchA 8217961 cchA Escherichia coli O157:H7 str. TW14359 carboxysome structural protein, ethanolamine utilization protein YP_003079238.1 3347341 R 544404 CDS YP_003079239.1 254794402 8217962 complement(3347673..3348689) 1 NC_013008.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 3348689 eutD 8217962 eutD Escherichia coli O157:H7 str. TW14359 phosphotransacetylase YP_003079239.1 3347673 R 544404 CDS YP_003079240.1 254794403 8217963 complement(3348686..3349417) 1 NC_013008.1 cobalamin adenosyltransferase in ethanolamine utilization 3349417 8217963 ECSP_3397 Escherichia coli O157:H7 str. TW14359 cobalamin adenosyltransferase in ethanolamine utilization YP_003079240.1 3348686 R 544404 CDS YP_003079241.1 254794404 8217964 complement(3349414..3350115) 1 NC_013008.1 hypothetical protein 3350115 8217964 ECSP_3398 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079241.1 3349414 R 544404 CDS YP_003079242.1 254794405 8217965 complement(3350090..3350569) 1 NC_013008.1 hypothetical protein 3350569 8217965 ECSP_3399 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079242.1 3350090 R 544404 CDS YP_003079243.1 254794406 8217966 complement(3350582..3350917) 1 NC_013008.1 carboxysome structural protein with role in ethanol utilization 3350917 8217966 ECSP_3400 Escherichia coli O157:H7 str. TW14359 carboxysome structural protein with role in ethanol utilization YP_003079243.1 3350582 R 544404 CDS YP_003079244.1 254794407 8217967 complement(3351210..3353489) 1 NC_013008.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 3353489 maeB 8217967 maeB Escherichia coli O157:H7 str. TW14359 malic enzyme YP_003079244.1 3351210 R 544404 CDS YP_003079245.1 254794408 8217968 3353778..3354728 1 NC_013008.1 transaldolase A 3354728 talA 8217968 talA Escherichia coli O157:H7 str. TW14359 transaldolase A YP_003079245.1 3353778 D 544404 CDS YP_003079246.1 254794409 8217969 3354748..3356751 1 NC_013008.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3356751 tktB 8217969 tktB Escherichia coli O157:H7 str. TW14359 transketolase YP_003079246.1 3354748 D 544404 CDS YP_003079247.1 254794410 8217970 complement(3356846..3357889) 1 NC_013008.1 hypothetical protein 3357889 ypfG 8217970 ypfG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079247.1 3356846 R 544404 CDS YP_003079248.1 254794411 8217971 complement(3358015..3358590) 1 NC_013008.1 GDP-mannose pyrophosphatase 3358590 nudK 8217971 nudK Escherichia coli O157:H7 str. TW14359 GDP-mannose pyrophosphatase YP_003079248.1 3358015 R 544404 CDS YP_003079249.1 254794412 8217972 complement(3358658..3360637) 1 NC_013008.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3360637 aegA 8217972 aegA Escherichia coli O157:H7 str. TW14359 oxidoreductase Fe-S binding subunit YP_003079249.1 3358658 R 544404 CDS YP_003079250.1 254794413 8217973 3360843..3362543 1 NC_013008.1 nitrate/nitrite sensor protein NarQ 3362543 narQ 8217973 narQ Escherichia coli O157:H7 str. TW14359 nitrate/nitrite sensor protein NarQ YP_003079250.1 3360843 D 544404 CDS YP_003079251.1 254794414 8217974 3362707..3365820 1 NC_013008.1 aminoglycoside/multidrug efflux system 3365820 acrD 8217974 acrD Escherichia coli O157:H7 str. TW14359 aminoglycoside/multidrug efflux system YP_003079251.1 3362707 D 544404 CDS YP_003079252.1 254794415 8217975 3366359..3366715 1 NC_013008.1 hypothetical protein 3366715 yffB 8217975 yffB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079252.1 3366359 D 544404 CDS YP_003079253.1 254794416 8217976 3366719..3367846 1 NC_013008.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 3367846 dapE 8217976 dapE Escherichia coli O157:H7 str. TW14359 succinyl-diaminopimelate desuccinylase YP_003079253.1 3366719 D 544404 CDS YP_003079254.1 254794417 8217977 3367874..3368074 1 NC_013008.1 hypothetical protein 3368074 ypfN 8217977 ypfN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079254.1 3367874 D 544404 CDS YP_003079255.1 254794418 8217978 complement(3368155..3368853) 1 NC_013008.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 3368853 ypfH 8217978 ypfH Escherichia coli O157:H7 str. TW14359 esterase YpfH YP_003079255.1 3368155 R 544404 CDS YP_003079256.1 254794419 8217979 complement(3368927..3370942) 1 NC_013008.1 hydrolase 3370942 ypfI 8217979 ypfI Escherichia coli O157:H7 str. TW14359 hydrolase YP_003079256.1 3368927 R 544404 CDS YP_003079257.1 254794420 8217980 complement(3370957..3371820) 1 NC_013008.1 hypothetical protein 3371820 ypfJ 8217980 ypfJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079257.1 3370957 R 544404 CDS YP_003079258.1 254794421 8217981 complement(3371988..3372701) 1 NC_013008.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 3372701 purC 8217981 purC Escherichia coli O157:H7 str. TW14359 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_003079258.1 3371988 R 544404 CDS YP_003079259.1 254794422 8217982 complement(3372914..3373948) 1 NC_013008.1 lipoprotein 3373948 nlpB 8217982 nlpB Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003079259.1 3372914 R 544404 CDS YP_003079260.1 254794423 8217983 complement(3373965..3374843) 1 NC_013008.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3374843 dapA 8217983 dapA Escherichia coli O157:H7 str. TW14359 dihydrodipicolinate synthase YP_003079260.1 3373965 R 544404 CDS YP_003079261.1 254794424 8217984 3374989..3375561 1 NC_013008.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 3375561 gcvR 8217984 gcvR Escherichia coli O157:H7 str. TW14359 glycine cleavage system transcriptional repressor YP_003079261.1 3374989 D 544404 CDS YP_003079262.1 254794425 8217985 3375561..3376031 1 NC_013008.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 3376031 bcp 8217985 bcp Escherichia coli O157:H7 str. TW14359 thioredoxin-dependent thiol peroxidase YP_003079262.1 3375561 D 544404 CDS YP_003079263.1 254794426 8217986 3376284..3376901 1 NC_013008.1 hydrogenase 4, 4Fe-4S subunit 3376901 hyfA 8217986 hyfA Escherichia coli O157:H7 str. TW14359 hydrogenase 4, 4Fe-4S subunit YP_003079263.1 3376284 D 544404 CDS YP_003079264.1 254794427 8217987 3376901..3378919 1 NC_013008.1 hydrogenase 4 subunit B 3378919 hyfB 8217987 hyfB Escherichia coli O157:H7 str. TW14359 hydrogenase 4 subunit B YP_003079264.1 3376901 D 544404 CDS YP_003079265.1 254794428 8217988 3378930..3379877 1 NC_013008.1 hydrogenase 4, membrane subunit 3379877 hyfC 8217988 hyfC Escherichia coli O157:H7 str. TW14359 hydrogenase 4, membrane subunit YP_003079265.1 3378930 D 544404 CDS YP_003079266.1 254794429 8217989 3379894..3381333 1 NC_013008.1 hydrogenase 4 subunit D 3381333 hyfD 8217989 hyfD Escherichia coli O157:H7 str. TW14359 hydrogenase 4 subunit D YP_003079266.1 3379894 D 544404 CDS YP_003079267.1 254794430 8217990 3381345..3381995 1 NC_013008.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 3381995 hyfE 8217990 hyfE Escherichia coli O157:H7 str. TW14359 hydrogenase 4 membrane subunit YP_003079267.1 3381345 D 544404 CDS YP_003079268.1 254794431 8217991 3382000..3383580 1 NC_013008.1 hydrogenase 4 subunit F 3383580 hyfF 8217991 hyfF Escherichia coli O157:H7 str. TW14359 hydrogenase 4 subunit F YP_003079268.1 3382000 D 544404 CDS YP_003079269.1 254794432 8217992 3383570..3385285 1 NC_013008.1 hydrogenase 4 subunit 3385285 hyfG 8217992 hyfG Escherichia coli O157:H7 str. TW14359 hydrogenase 4 subunit YP_003079269.1 3383570 D 544404 CDS YP_003079270.1 254794433 8217993 3385295..3385840 1 NC_013008.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 3385840 hyfH 8217993 hyfH Escherichia coli O157:H7 str. TW14359 hydrogenase 4 subunit H YP_003079270.1 3385295 D 544404 CDS YP_003079271.1 254794434 8217994 3385837..3386595 1 NC_013008.1 hydrogenase 4, Fe-S subunit 3386595 hyfI 8217994 hyfI Escherichia coli O157:H7 str. TW14359 hydrogenase 4, Fe-S subunit YP_003079271.1 3385837 D 544404 CDS YP_003079272.1 254794435 8217995 3386588..3387001 1 NC_013008.1 processing element hydrogenase 4 3387001 hyfJ 8217995 hyfJ Escherichia coli O157:H7 str. TW14359 processing element hydrogenase 4 YP_003079272.1 3386588 D 544404 CDS YP_003079273.1 254794436 8217996 3387031..3389043 1 NC_013008.1 DNA-binding transcriptional activator, formate sensing 3389043 hyfR 8217996 hyfR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator, formate sensing YP_003079273.1 3387031 D 544404 CDS YP_003079274.1 254794437 8217997 3389065..3389913 1 NC_013008.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; formate transporter 3389913 focB 8217997 focB Escherichia coli O157:H7 str. TW14359 formate transporter YP_003079274.1 3389065 D 544404 CDS YP_003079275.1 254794438 8217998 complement(3389951..3391012) 1 NC_013008.1 inner membrane protein 3391012 yfgO 8217998 yfgO Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079275.1 3389951 R 544404 CDS YP_003079276.1 254794439 8217999 3391225..3392688 1 NC_013008.1 peptidase 3392688 yfgC 8217999 yfgC Escherichia coli O157:H7 str. TW14359 peptidase YP_003079276.1 3391225 D 544404 CDS YP_003079277.1 254794440 8218000 3392709..3393068 1 NC_013008.1 oxidoreductase 3393068 yfgD 8218000 yfgD Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003079277.1 3392709 D 544404 CDS YP_003079278.1 254794441 8218001 complement(3393206..3393952) 1 NC_013008.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 3393952 hda 8218001 hda Escherichia coli O157:H7 str. TW14359 DNA replication initiation factor YP_003079278.1 3393206 R 544404 CDS YP_003079279.1 254794442 8218002 complement(3394002..3395291) 1 NC_013008.1 uracil transporter 3395291 uraA 8218002 uraA Escherichia coli O157:H7 str. TW14359 uracil transporter YP_003079279.1 3394002 R 544404 CDS YP_003079280.1 254794443 8218003 complement(3395377..3396003) 1 NC_013008.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 3396003 upp 8218003 upp Escherichia coli O157:H7 str. TW14359 uracil phosphoribosyltransferase YP_003079280.1 3395377 R 544404 CDS YP_003079281.1 254794444 8218004 3396328..3397365 1 NC_013008.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 3397365 purM 8218004 purM Escherichia coli O157:H7 str. TW14359 phosphoribosylaminoimidazole synthetase YP_003079281.1 3396328 D 544404 CDS YP_003079282.1 254794445 8218005 3397365..3398003 1 NC_013008.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3398003 purN 8218005 purN Escherichia coli O157:H7 str. TW14359 phosphoribosylglycinamide formyltransferase YP_003079282.1 3397365 D 544404 CDS YP_003079283.1 254794446 8218006 3398174..3400240 1 NC_013008.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3400240 ppk 8218006 ppk Escherichia coli O157:H7 str. TW14359 polyphosphate kinase YP_003079283.1 3398174 D 544404 CDS YP_003079284.1 254794447 8218007 3400245..3401786 1 NC_013008.1 exopolyphosphatase 3401786 ppx 8218007 ppx Escherichia coli O157:H7 str. TW14359 exopolyphosphatase YP_003079284.1 3400245 D 544404 CDS YP_003079285.1 254794448 8218008 complement(3401825..3404068) 1 NC_013008.1 inner membrane protein 3404068 yfgF 8218008 yfgF Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079285.1 3401825 R 544404 CDS YP_003079286.1 254794449 8218009 complement(3404250..3404402) 1 NC_013008.1 hypothetical protein 3404402 8218009 ECSP_3443 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079286.1 3404250 R 544404 CDS YP_003079287.1 254794450 8218010 3404420..3404611 1 NC_013008.1 hypothetical protein 3404611 yfgG 8218010 yfgG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079287.1 3404420 D 544404 CDS YP_003079288.1 254794451 8218011 3404922..3405440 1 NC_013008.1 outer membrane lipoprotein 3405440 yfgH 8218011 yfgH Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003079288.1 3404922 D 544404 CDS YP_003079289.1 254794452 8218012 3405456..3405995 1 NC_013008.1 hypothetical protein 3405995 yfgI 8218012 yfgI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079289.1 3405456 D 544404 CDS YP_003079290.1 254794453 8218013 complement(3406088..3407665) 1 NC_013008.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3407665 guaA 8218013 guaA Escherichia coli O157:H7 str. TW14359 GMP synthase YP_003079290.1 3406088 R 544404 CDS YP_003079291.1 254794454 8218014 complement(3407734..3409200) 1 NC_013008.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 3409200 guaB 8218014 guaB Escherichia coli O157:H7 str. TW14359 inosine 5'-monophosphate dehydrogenase YP_003079291.1 3407734 R 544404 CDS YP_003079292.1 254794455 8218015 3409362..3410732 1 NC_013008.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3410732 xseA 8218015 xseA Escherichia coli O157:H7 str. TW14359 exodeoxyribonuclease VII large subunit YP_003079292.1 3409362 D 544404 CDS YP_003079293.1 254794456 8218016 complement(3410729..3410944) 1 NC_013008.1 hypothetical protein 3410944 yfgJ 8218016 yfgJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079293.1 3410729 R 544404 CDS YP_003079294.1 254794457 8218017 complement(3411013..3412485) 1 NC_013008.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 3412485 engA 8218017 engA Escherichia coli O157:H7 str. TW14359 GTP-binding protein EngA YP_003079294.1 3411013 R 544404 CDS YP_003079295.1 254794458 8218018 complement(3412603..3413781) 1 NC_013008.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 3413781 yfgL 8218018 yfgL Escherichia coli O157:H7 str. TW14359 outer membrane protein assembly complex subunit YfgL YP_003079295.1 3412603 R 544404 CDS YP_003079296.1 254794459 8218019 complement(3413792..3414412) 1 NC_013008.1 hypothetical protein 3414412 yfgM 8218019 yfgM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079296.1 3413792 R 544404 CDS YP_003079297.1 254794460 8218020 complement(3414430..3415704) 1 NC_013008.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 3415704 hisS 8218020 hisS Escherichia coli O157:H7 str. TW14359 histidyl-tRNA synthetase YP_003079297.1 3414430 R 544404 CDS YP_003079298.1 254794461 8218021 complement(3415815..3416933) 1 NC_013008.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3416933 ispG 8218021 ispG Escherichia coli O157:H7 str. TW14359 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_003079298.1 3415815 R 544404 CDS YP_003079299.1 254794462 8218022 complement(3416960..3417973) 1 NC_013008.1 cytoskeletal protein RodZ 3417973 yfgA 8218022 yfgA Escherichia coli O157:H7 str. TW14359 cytoskeletal protein RodZ YP_003079299.1 3416960 R 544404 CDS YP_003079300.1 254794463 8218023 complement(3418258..3419412) 1 NC_013008.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 3419412 yfgB 8218023 yfgB Escherichia coli O157:H7 str. TW14359 ribosomal RNA large subunit methyltransferase N YP_003079300.1 3418258 R 544404 CDS YP_003079301.1 254794464 8218024 complement(3419562..3419993) 1 NC_013008.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 3419993 ndk 8218024 ndk Escherichia coli O157:H7 str. TW14359 nucleoside diphosphate kinase YP_003079301.1 3419562 R 544404 CDS YP_003079302.1 254794465 8218025 complement(3420134..3420712) 1 NC_013008.1 hypothetical protein 3420712 8218025 ECSP_3459 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079302.1 3420134 R 544404 CDS YP_003079303.1 254794466 8218026 complement(3420988..3421809) 1 NC_013008.1 dimethyl sulfoxide reductase subunit C 3421809 8218026 ECSP_3460 Escherichia coli O157:H7 str. TW14359 dimethyl sulfoxide reductase subunit C YP_003079303.1 3420988 R 544404 CDS YP_003079304.1 254794467 8218027 complement(3421802..3422431) 1 NC_013008.1 dimethyl sulfoxide reductase subunit B 3422431 8218027 ECSP_3461 Escherichia coli O157:H7 str. TW14359 dimethyl sulfoxide reductase subunit B YP_003079304.1 3421802 R 544404 CDS YP_003079305.1 254794468 8218028 complement(3422428..3424809) 1 NC_013008.1 dimethyl sulfoxide reductase subunit A 3424809 8218028 ECSP_3462 Escherichia coli O157:H7 str. TW14359 dimethyl sulfoxide reductase subunit A YP_003079305.1 3422428 R 544404 CDS YP_003079306.1 254794469 8218029 complement(3424973..3427285) 1 NC_013008.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 3427285 pbpC 8218029 pbpC Escherichia coli O157:H7 str. TW14359 penicillin-binding protein 1C YP_003079306.1 3424973 R 544404 CDS YP_003079307.1 254794470 8218030 complement(3427286..3432247) 1 NC_013008.1 hypothetical protein 3432247 yfhM 8218030 yfhM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079307.1 3427286 R 544404 CDS YP_003079308.1 254794471 8218031 3432454..3433299 1 NC_013008.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 3433299 sseA 8218031 sseA Escherichia coli O157:H7 str. TW14359 3-mercaptopyruvate sulfurtransferase YP_003079308.1 3432454 D 544404 CDS YP_003079309.1 254794472 8218032 complement(3433799..3434587) 1 NC_013008.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 3434587 sseB 8218032 sseB Escherichia coli O157:H7 str. TW14359 enhanced serine sensitivity protein SseB YP_003079309.1 3433799 R 544404 CDS YP_003079310.1 254794473 8218033 complement(3434718..3436001) 1 NC_013008.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 3436001 pepB 8218033 pepB Escherichia coli O157:H7 str. TW14359 aminopeptidase YP_003079310.1 3434718 R 544404 CDS YP_003079311.1 254794474 8218034 complement(3436179..3436379) 1 NC_013008.1 hypothetical protein 3436379 iscX 8218034 iscX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079311.1 3436179 R 544404 CDS YP_003079312.1 254794475 8218035 complement(3436391..3436726) 1 NC_013008.1 [2Fe-2S] ferredoxin 3436726 fdx 8218035 fdx Escherichia coli O157:H7 str. TW14359 [2Fe-2S] ferredoxin YP_003079312.1 3436391 R 544404 CDS YP_003079313.1 254794476 8218036 complement(3436728..3438578) 1 NC_013008.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 3438578 hscA 8218036 hscA Escherichia coli O157:H7 str. TW14359 chaperone protein HscA YP_003079313.1 3436728 R 544404 CDS YP_003079314.1 254794477 8218037 complement(3438595..3439110) 1 NC_013008.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 3439110 hscB 8218037 hscB Escherichia coli O157:H7 str. TW14359 co-chaperone HscB YP_003079314.1 3438595 R 544404 CDS YP_003079315.1 254794478 8218038 complement(3439206..3439529) 1 NC_013008.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 3439529 iscA 8218038 iscA Escherichia coli O157:H7 str. TW14359 iron-sulfur cluster assembly protein YP_003079315.1 3439206 R 544404 CDS YP_003079316.1 254794479 8218039 complement(3439546..3439932) 1 NC_013008.1 scaffold protein 3439932 iscU 8218039 iscU Escherichia coli O157:H7 str. TW14359 scaffold protein YP_003079316.1 3439546 R 544404 CDS YP_003079317.1 254794480 8218040 complement(3439960..3441174) 1 NC_013008.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 3441174 iscS 8218040 iscS Escherichia coli O157:H7 str. TW14359 cysteine desulfurase YP_003079317.1 3439960 R 544404 CDS YP_003079318.1 254794481 8218041 complement(3441286..3441774) 1 NC_013008.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 3441774 iscR 8218041 iscR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator IscR YP_003079318.1 3441286 R 544404 CDS YP_003079319.1 254794482 8218042 complement(3442075..3442812) 1 NC_013008.1 tRNA Cm32/Um32 methyltransferase 3442812 trmJ 8218042 trmJ Escherichia coli O157:H7 str. TW14359 tRNA Cm32/Um32 methyltransferase YP_003079319.1 3442075 R 544404 CDS YP_003079320.1 254794483 8218043 3442931..3443734 1 NC_013008.1 inositol monophosphatase 3443734 suhB 8218043 suhB Escherichia coli O157:H7 str. TW14359 inositol monophosphatase YP_003079320.1 3442931 D 544404 CDS YP_003079321.1 254794484 8218044 3443879..3444733 1 NC_013008.1 peptidase 3444733 yfhR 8218044 yfhR Escherichia coli O157:H7 str. TW14359 peptidase YP_003079321.1 3443879 D 544404 CDS YP_003079322.1 254794485 8218045 3444924..3446204 1 NC_013008.1 stationary phase inducible protein CsiE 3446204 csiE 8218045 csiE Escherichia coli O157:H7 str. TW14359 stationary phase inducible protein CsiE YP_003079322.1 3444924 D 544404 CDS YP_003079323.1 254794486 8218046 complement(3446196..3447335) 1 NC_013008.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 3447335 hcaT 8218046 hcaT Escherichia coli O157:H7 str. TW14359 3-phenylpropionic acid transporter YP_003079323.1 3446196 R 544404 CDS YP_003079324.1 254794487 8218047 complement(3447495..3448385) 1 NC_013008.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 3448385 hcaR 8218047 hcaR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator HcaR YP_003079324.1 3447495 R 544404 CDS YP_003079325.1 254794488 8218048 3448521..3449882 1 NC_013008.1 3-phenylpropionate dioxygenase large subunit alpha 3449882 hcaE 8218048 hcaE Escherichia coli O157:H7 str. TW14359 3-phenylpropionate dioxygenase large subunit alpha YP_003079325.1 3448521 D 544404 CDS YP_003079326.1 254794489 8218049 3449879..3450397 1 NC_013008.1 3-phenylpropionate dioxygenase subunit beta 3450397 hcaF 8218049 hcaF Escherichia coli O157:H7 str. TW14359 3-phenylpropionate dioxygenase subunit beta YP_003079326.1 3449879 D 544404 CDS YP_003079327.1 254794490 8218050 3450397..3450717 1 NC_013008.1 3-phenylpropionate dioxygenase ferredoxin subunit 3450717 hcaC 8218050 hcaC Escherichia coli O157:H7 str. TW14359 3-phenylpropionate dioxygenase ferredoxin subunit YP_003079327.1 3450397 D 544404 CDS YP_003079328.1 254794491 8218051 3450714..3451526 1 NC_013008.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 3451526 hcaB 8218051 hcaB Escherichia coli O157:H7 str. TW14359 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_003079328.1 3450714 D 544404 CDS YP_003079329.1 254794492 8218052 3451536..3452738 1 NC_013008.1 phenylpropionate dioxygenase ferredoxin reductase subunit 3452738 hcaD 8218052 hcaD Escherichia coli O157:H7 str. TW14359 phenylpropionate dioxygenase ferredoxin reductase subunit YP_003079329.1 3451536 D 544404 CDS YP_003079330.1 254794493 8218053 3452835..3453257 1 NC_013008.1 inner membrane protein 3453257 yphA 8218053 yphA Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079330.1 3452835 D 544404 CDS YP_003079331.1 254794494 8218054 complement(3453305..3454177) 1 NC_013008.1 hypothetical protein 3454177 yphB 8218054 yphB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079331.1 3453305 R 544404 CDS YP_003079332.1 254794495 8218056 complement(3455316..3456314) 1 NC_013008.1 sugar ABC transporter membrane protein 3456314 yphD 8218056 yphD Escherichia coli O157:H7 str. TW14359 sugar ABC transporter membrane protein YP_003079332.1 3455316 R 544404 CDS YP_003079333.1 254794496 8218057 complement(3456339..3457850) 1 NC_013008.1 sugar ABC transporter ATP-binding protein 3457850 yphE 8218057 yphE Escherichia coli O157:H7 str. TW14359 sugar ABC transporter ATP-binding protein YP_003079333.1 3456339 R 544404 CDS YP_003079334.1 254794497 8218058 complement(3457873..3458856) 1 NC_013008.1 sugar ABC transporter periplasmic-binding protein 3458856 yphF 8218058 yphF Escherichia coli O157:H7 str. TW14359 sugar ABC transporter periplasmic-binding protein YP_003079334.1 3457873 R 544404 CDS YP_003079335.1 254794498 8218059 complement(3458953..3462234) 1 NC_013008.1 hypothetical protein 3462234 yphG 8218059 yphG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079335.1 3458953 R 544404 CDS YP_003079336.1 254794499 8218060 3462352..3463545 1 NC_013008.1 DNA-binding transcriptional regulator 3463545 yphH 8218060 yphH Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079336.1 3462352 D 544404 CDS YP_003079337.1 254794500 8218061 complement(3463608..3464861) 1 NC_013008.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3464861 glyA 8218061 glyA Escherichia coli O157:H7 str. TW14359 serine hydroxymethyltransferase YP_003079337.1 3463608 R 544404 CDS YP_003079338.1 254794501 8218062 3465189..3466379 1 NC_013008.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 3466379 hmp 8218062 hmp Escherichia coli O157:H7 str. TW14359 nitric oxide dioxygenase YP_003079338.1 3465189 D 544404 CDS YP_003079339.1 254794502 8218063 complement(3466424..3466762) 1 NC_013008.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 3466762 glnB 8218063 glnB Escherichia coli O157:H7 str. TW14359 nitrogen regulatory protein P-II 1 YP_003079339.1 3466424 R 544404 CDS YP_003079340.1 254794503 8218064 complement(3466823..3468157) 1 NC_013008.1 DNA-binding response regulator in two-component regulatory system with QseE 3468157 qseF 8218064 qseF Escherichia coli O157:H7 str. TW14359 DNA-binding response regulator in two-component regulatory system with QseE YP_003079340.1 3466823 R 544404 CDS YP_003079341.1 254794504 8218065 complement(3468147..3468860) 1 NC_013008.1 hypothetical protein 3468860 yfhG 8218065 yfhG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079341.1 3468147 R 544404 CDS YP_003079342.1 254794505 8218066 complement(3469025..3470452) 1 NC_013008.1 sensory histidine kinase in two-component regulatory system with QseF 3470452 qseE 8218066 qseE Escherichia coli O157:H7 str. TW14359 sensory histidine kinase in two-component regulatory system with QseF YP_003079342.1 3469025 R 544404 CDS YP_003079343.1 254794506 8218067 complement(3471028..3474915) 1 NC_013008.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 3474915 purL 8218067 purL Escherichia coli O157:H7 str. TW14359 phosphoribosylformylglycinamidine synthase YP_003079343.1 3471028 R 544404 CDS YP_003079344.1 254794507 8218068 3475172..3476728 1 NC_013008.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 3476728 yfhD 8218068 yfhD Escherichia coli O157:H7 str. TW14359 transglycosylase YP_003079344.1 3475172 D 544404 CDS YP_003079345.1 254794508 8218069 complement(3476725..3477228) 1 NC_013008.1 tRNA-specific adenosine deaminase 3477228 tadA 8218069 tadA Escherichia coli O157:H7 str. TW14359 tRNA-specific adenosine deaminase YP_003079345.1 3476725 R 544404 CDS YP_003079346.1 254794509 8218070 complement(3477286..3477921) 1 NC_013008.1 hypothetical protein 3477921 yfhB 8218070 yfhB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079346.1 3477286 R 544404 CDS YP_003079347.1 254794510 8218071 3478130..3478978 1 NC_013008.1 DNA-binding transcriptional regulator 3478978 yfhH 8218071 yfhH Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079347.1 3478130 D 544404 CDS YP_003079348.1 254794511 8218072 3479034..3479294 1 NC_013008.1 4Fe-4S cluster-containing protein 3479294 yfhL 8218072 yfhL Escherichia coli O157:H7 str. TW14359 4Fe-4S cluster-containing protein YP_003079348.1 3479034 D 544404 CDS YP_003079349.1 254794512 8218073 complement(3479565..3479717) 1 NC_013008.1 hypothetical protein 3479717 8218073 ECSP_3507 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079349.1 3479565 R 544404 CDS YP_003079350.1 254794513 8218074 complement(3479990..3480370) 1 NC_013008.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 3480370 acpS 8218074 acpS Escherichia coli O157:H7 str. TW14359 4'-phosphopantetheinyl transferase YP_003079350.1 3479990 R 544404 CDS YP_003079351.1 254794514 8218075 complement(3480370..3481101) 1 NC_013008.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 3481101 pdxJ 8218075 pdxJ Escherichia coli O157:H7 str. TW14359 pyridoxine 5'-phosphate synthase YP_003079351.1 3480370 R 544404 CDS YP_003079352.1 254794515 8218076 complement(3481113..3481841) 1 NC_013008.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 3481841 recO 8218076 recO Escherichia coli O157:H7 str. TW14359 DNA repair protein RecO YP_003079352.1 3481113 R 544404 CDS YP_003079353.1 254794516 8218077 complement(3481853..3482758) 1 NC_013008.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 3482758 era 8218077 era Escherichia coli O157:H7 str. TW14359 GTP-binding protein Era YP_003079353.1 3481853 R 544404 CDS YP_003079354.1 254794517 8218078 complement(3482755..3483435) 1 NC_013008.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 3483435 rnc 8218078 rnc Escherichia coli O157:H7 str. TW14359 ribonuclease III YP_003079354.1 3482755 R 544404 CDS YP_003079355.1 254794518 8218079 3483493..3483657 1 NC_013008.1 hypothetical protein 3483657 8218079 ECSP_3513 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079355.1 3483493 D 544404 CDS YP_003079356.1 254794519 8218080 complement(3483708..3484682) 1 NC_013008.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 3484682 lepB 8218080 lepB Escherichia coli O157:H7 str. TW14359 signal peptidase I YP_003079356.1 3483708 R 544404 CDS YP_003079357.1 254794520 8218081 complement(3484698..3486497) 1 NC_013008.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 3486497 lepA 8218081 lepA Escherichia coli O157:H7 str. TW14359 GTP-binding protein LepA YP_003079357.1 3484698 R 544404 CDS YP_003079358.1 254794521 8218082 complement(3486695..3487174) 1 NC_013008.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 3487174 rseC 8218082 rseC Escherichia coli O157:H7 str. TW14359 SoxR reducing system protein RseC YP_003079358.1 3486695 R 544404 CDS YP_003079359.1 254794522 8218083 complement(3487171..3488127) 1 NC_013008.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 3488127 rseB 8218083 rseB Escherichia coli O157:H7 str. TW14359 periplasmic negative regulator of sigmaE YP_003079359.1 3487171 R 544404 CDS YP_003079360.1 254794523 8218084 complement(3488127..3488765) 1 NC_013008.1 anti-RNA polymerase sigma factor SigE 3488765 rseA 8218084 rseA Escherichia coli O157:H7 str. TW14359 anti-RNA polymerase sigma factor SigE YP_003079360.1 3488127 R 544404 CDS YP_003079361.1 254794524 8218085 complement(3488798..3489373) 1 NC_013008.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 3489373 rpoE 8218085 rpoE Escherichia coli O157:H7 str. TW14359 RNA polymerase sigma factor RpoE YP_003079361.1 3488798 R 544404 CDS YP_003079362.1 254794525 8218086 3489781..3491403 1 NC_013008.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 3491403 nadB 8218086 nadB Escherichia coli O157:H7 str. TW14359 L-aspartate oxidase YP_003079362.1 3489781 D 544404 CDS YP_003079363.1 254794526 8218087 complement(3491388..3492125) 1 NC_013008.1 S-adenosyl-L-methionine-dependent methyltransferase 3492125 yfiC 8218087 yfiC Escherichia coli O157:H7 str. TW14359 S-adenosyl-L-methionine-dependent methyltransferase YP_003079363.1 3491388 R 544404 CDS YP_003079364.1 254794527 8218088 3492257..3493591 1 NC_013008.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3493591 srmB 8218088 srmB Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase SrmB YP_003079364.1 3492257 D 544404 CDS YP_003079365.1 254794528 8218089 complement(3493624..3494505) 1 NC_013008.1 DNA-binding transcriptional regulator 3494505 yfiE 8218089 yfiE Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079365.1 3493624 R 544404 CDS YP_003079366.1 254794529 8218090 3494608..3495195 1 NC_013008.1 neutral amino-acid efflux protein 3495195 yfiK 8218090 yfiK Escherichia coli O157:H7 str. TW14359 neutral amino-acid efflux protein YP_003079366.1 3494608 D 544404 CDS YP_003079367.1 254794530 8218091 complement(3495251..3495634) 1 NC_013008.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 3495634 yfiD 8218091 yfiD Escherichia coli O157:H7 str. TW14359 autonomous glycyl radical cofactor GrcA YP_003079367.1 3495251 R 544404 CDS YP_003079368.1 254794531 8218092 3495939..3496628 1 NC_013008.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3496628 ung 8218092 ung Escherichia coli O157:H7 str. TW14359 uracil-DNA glycosylase YP_003079368.1 3495939 D 544404 CDS YP_003079369.1 254794532 8218093 complement(3496676..3497713) 1 NC_013008.1 methyltransferase 3497713 yfiF 8218093 yfiF Escherichia coli O157:H7 str. TW14359 methyltransferase YP_003079369.1 3496676 R 544404 CDS YP_003079370.1 254794533 8218094 complement(3497703..3497906) 1 NC_013008.1 hypothetical protein 3497906 8218094 ECSP_3528 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079370.1 3497703 R 544404 CDS YP_003079371.1 254794534 8218095 3497920..3498339 1 NC_013008.1 thioredoxin 2 3498339 trxC 8218095 trxC Escherichia coli O157:H7 str. TW14359 thioredoxin 2 YP_003079371.1 3497920 D 544404 CDS YP_003079372.1 254794535 8218096 3498408..3499106 1 NC_013008.1 hypothetical protein 3499106 yfiP 8218096 yfiP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079372.1 3498408 D 544404 CDS YP_003079373.1 254794536 8218097 3499138..3501798 1 NC_013008.1 acyl-CoA synthetase: NAD(P)-binding subunit and ATP-binding subunit 3501798 yfiQ 8218097 yfiQ Escherichia coli O157:H7 str. TW14359 acyl-CoA synthetase: NAD(P)-binding subunit and ATP-binding subunit YP_003079373.1 3499138 D 544404 CDS YP_003079374.1 254794537 8218098 3501912..3503267 1 NC_013008.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3503267 pssA 8218098 pssA Escherichia coli O157:H7 str. TW14359 phosphatidylserine synthase YP_003079374.1 3501912 D 544404 CDS YP_003079375.1 254794538 8218099 3503313..3503636 1 NC_013008.1 hypothetical protein 3503636 yfiM 8218099 yfiM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079375.1 3503313 D 544404 CDS YP_003079376.1 254794539 8218100 complement(3503633..3504931) 1 NC_013008.1 alpha-ketoglutarate transporter 3504931 kgtP 8218100 kgtP Escherichia coli O157:H7 str. TW14359 alpha-ketoglutarate transporter YP_003079376.1 3503633 R 544404 CDS YP_003079377.1 254794540 8218105 complement(3510705..3513278) 1 NC_013008.1 protein disaggregation chaperone 3513278 clpB 8218105 clpB Escherichia coli O157:H7 str. TW14359 protein disaggregation chaperone YP_003079377.1 3510705 R 544404 CDS YP_003079378.1 254794541 8218106 complement(3513408..3514139) 1 NC_013008.1 hypothetical protein 3514139 yfiH 8218106 yfiH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079378.1 3513408 R 544404 CDS YP_003079379.1 254794542 8218107 complement(3514136..3515116) 1 NC_013008.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 3515116 rluD 8218107 rluD Escherichia coli O157:H7 str. TW14359 23S rRNA pseudouridine synthase D YP_003079379.1 3514136 R 544404 CDS YP_003079380.1 254794543 8218108 3515251..3515988 1 NC_013008.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3515988 yfiO 8218108 yfiO Escherichia coli O157:H7 str. TW14359 outer membrane protein assembly complex subunit YfiO YP_003079380.1 3515251 D 544404 CDS YP_003079381.1 254794544 8218109 3516259..3516600 1 NC_013008.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3516600 raiA 8218109 raiA Escherichia coli O157:H7 str. TW14359 translation inhibitor protein RaiA YP_003079381.1 3516259 D 544404 CDS YP_003079382.1 254794545 8218110 3516850..3518010 1 NC_013008.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3518010 pheA 8218110 pheA Escherichia coli O157:H7 str. TW14359 bifunctional chorismate mutase/prephenate dehydratase YP_003079382.1 3516850 D 544404 CDS YP_003079383.1 254794546 8218111 complement(3518053..3519174) 1 NC_013008.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 3519174 tyrA 8218111 tyrA Escherichia coli O157:H7 str. TW14359 bifunctional chorismate mutase/prephenate dehydrogenase YP_003079383.1 3518053 R 544404 CDS YP_003079384.1 254794547 8218112 complement(3519185..3520255) 1 NC_013008.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3520255 aroF 8218112 aroF Escherichia coli O157:H7 str. TW14359 phospho-2-dehydro-3-deoxyheptonate aldolase YP_003079384.1 3519185 R 544404 CDS YP_003079385.1 254794548 8218113 3520465..3520830 1 NC_013008.1 hypothetical protein 3520830 yfiL 8218113 yfiL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079385.1 3520465 D 544404 CDS YP_003079386.1 254794549 8218114 3520980..3521498 1 NC_013008.1 hypothetical protein 3521498 yfiR 8218114 yfiR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079386.1 3520980 D 544404 CDS YP_003079387.1 254794550 8218115 3521488..3522714 1 NC_013008.1 hypothetical protein 3522714 yfiN 8218115 yfiN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079387.1 3521488 D 544404 CDS YP_003079388.1 254794551 8218116 3522730..3523212 1 NC_013008.1 outer membrane lipoprotein 3523212 yfiB 8218116 yfiB Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003079388.1 3522730 D 544404 CDS YP_003079389.1 254794552 8218117 complement(3523289..3523636) 1 NC_013008.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3523636 rplS 8218117 rplS Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L19 YP_003079389.1 3523289 R 544404 CDS YP_003079390.1 254794553 8218118 complement(3523678..3524445) 1 NC_013008.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3524445 trmD 8218118 trmD Escherichia coli O157:H7 str. TW14359 tRNA (guanine-N(1)-)-methyltransferase YP_003079390.1 3523678 R 544404 CDS YP_003079391.1 254794554 8218119 complement(3524476..3525024) 1 NC_013008.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3525024 rimM 8218119 rimM Escherichia coli O157:H7 str. TW14359 16S rRNA-processing protein RimM YP_003079391.1 3524476 R 544404 CDS YP_003079392.1 254794555 8218120 complement(3525043..3525291) 1 NC_013008.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3525291 rpsP 8218120 rpsP Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S16 YP_003079392.1 3525043 R 544404 CDS YP_003079393.1 254794556 8218121 complement(3525428..3526789) 1 NC_013008.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 3526789 ffh 8218121 ffh Escherichia coli O157:H7 str. TW14359 signal recognition particle protein YP_003079393.1 3525428 R 544404 CDS YP_003079394.1 254794557 8218122 3526881..3527747 1 NC_013008.1 inner membrane protein 3527747 ypjD 8218122 ypjD Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079394.1 3526881 D 544404 CDS YP_003079395.1 254794558 8218123 3527769..3528548 1 NC_013008.1 inner membrane protein 3528548 yfjD 8218123 yfjD Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079395.1 3527769 D 544404 CDS YP_003079396.1 254794559 8218124 complement(3529109..3529702) 1 NC_013008.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 3529702 grpE 8218124 grpE Escherichia coli O157:H7 str. TW14359 heat shock protein GrpE YP_003079396.1 3529109 R 544404 CDS YP_003079397.1 254794560 8218125 3529825..3530703 1 NC_013008.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3530703 ppnK 8218125 ppnK Escherichia coli O157:H7 str. TW14359 inorganic polyphosphate/ATP-NAD kinase YP_003079397.1 3529825 D 544404 CDS YP_003079398.1 254794561 8218126 3530789..3532450 1 NC_013008.1 recombination and repair protein 3532450 recN 8218126 recN Escherichia coli O157:H7 str. TW14359 recombination and repair protein YP_003079398.1 3530789 D 544404 CDS YP_003079399.1 254794562 8218127 3532599..3532940 1 NC_013008.1 hypothetical protein 3532940 smpA 8218127 smpA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079399.1 3532599 D 544404 CDS YP_003079400.1 254794563 8218128 complement(3533002..3533292) 1 NC_013008.1 hypothetical protein 3533292 yfjF 8218128 yfjF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079400.1 3533002 R 544404 CDS YP_003079401.1 254794564 8218129 complement(3533282..3533758) 1 NC_013008.1 hypothetical protein 3533758 yfjG 8218129 yfjG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079401.1 3533282 R 544404 CDS YP_003079402.1 254794565 8218130 3533890..3534372 1 NC_013008.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3534372 smpB 8218130 smpB Escherichia coli O157:H7 str. TW14359 SsrA-binding protein YP_003079402.1 3533890 D 544404 CDS YP_003079403.1 254794566 8218131 3535218..3535466 1 NC_013008.1 hypothetical protein 3535466 8218131 ECSP_3565 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079403.1 3535218 D 544404 CDS YP_003079404.1 254794567 8218132 3535587..3535790 1 NC_013008.1 hypothetical protein 3535790 8218132 ECSP_3566 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079404.1 3535587 D 544404 CDS YP_003079405.1 254794568 8218133 complement(3535968..3536552) 1 NC_013008.1 non-LEE-encoded type III effector 3536552 espM2 8218133 espM2 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003079405.1 3535968 R 544404 CDS YP_003079406.1 254794569 8218134 3536741..3537391 1 NC_013008.1 non-LEE-encoded type III effector 3537391 8218134 ECSP_3568 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003079406.1 3536741 D 544404 CDS YP_003079407.1 254794570 8218135 3537470..3538528 1 NC_013008.1 non-LEE-encoded type III effector 3538528 espW 8218135 espW Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003079407.1 3537470 D 544404 CDS YP_003079408.1 254794571 8218136 complement(3538658..3539065) 1 NC_013008.1 hypothetical protein 3539065 8218136 ECSP_3570 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079408.1 3538658 R 544404 CDS YP_003079409.1 254794572 8218137 complement(3539241..3539510) 1 NC_013008.1 hypothetical protein 3539510 8218137 ECSP_3571 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079409.1 3539241 R 544404 CDS YP_003079410.1 254794573 8218138 3539728..3540054 1 NC_013008.1 transposase 3540054 8218138 ECSP_3572 Escherichia coli O157:H7 str. TW14359 transposase YP_003079410.1 3539728 D 544404 CDS YP_003079411.1 254794574 8218139 3540051..3540941 1 NC_013008.1 transposase 3540941 8218139 ECSP_3573 Escherichia coli O157:H7 str. TW14359 transposase YP_003079411.1 3540051 D 544404 CDS YP_003079412.1 254794575 8218140 complement(3540748..3541392) 1 NC_013008.1 hypothetical protein 3541392 8218140 ECSP_3574 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079412.1 3540748 R 544404 CDS YP_003079413.1 254794576 8218141 complement(3541442..3541789) 1 NC_013008.1 hypothetical protein 3541789 8218141 ECSP_3575 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079413.1 3541442 R 544404 CDS YP_003079414.1 254794577 8218142 complement(3541786..3542187) 1 NC_013008.1 hypothetical protein 3542187 8218142 ECSP_3576 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079414.1 3541786 R 544404 CDS YP_003079415.1 254794578 8218143 complement(3542242..3542472) 1 NC_013008.1 phage-related lysozyme 3542472 8218143 ECSP_3577 Escherichia coli O157:H7 str. TW14359 phage-related lysozyme YP_003079415.1 3542242 R 544404 CDS YP_003079416.1 254794579 8218144 complement(3542523..3542867) 1 NC_013008.1 hypothetical protein 3542867 8218144 ECSP_3578 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079416.1 3542523 R 544404 CDS YP_003079417.1 254794580 8218145 complement(3542872..3543186) 1 NC_013008.1 holin protein of prophage CP-933U 3543186 8218145 ECSP_3579 Escherichia coli O157:H7 str. TW14359 holin protein of prophage CP-933U YP_003079417.1 3542872 R 544404 CDS YP_003079418.1 254794581 8218146 complement(3543237..3545090) 1 NC_013008.1 hypothetical protein 3545090 8218146 ECSP_3580 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079418.1 3543237 R 544404 CDS YP_003079419.1 254794582 8218147 complement(3545498..3545608) 1 NC_013008.1 hypothetical protein 3545608 8218147 ECSP_3581 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079419.1 3545498 R 544404 CDS YP_003079420.1 254794583 8218148 complement(3545751..3546467) 1 NC_013008.1 hypothetical protein 3546467 8218148 ECSP_3582 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079420.1 3545751 R 544404 CDS YP_003079421.1 254794584 8218149 complement(3546747..3547370) 1 NC_013008.1 antiterminator of prophage CP-933Y 3547370 8218149 ECSP_3583 Escherichia coli O157:H7 str. TW14359 antiterminator of prophage CP-933Y YP_003079421.1 3546747 R 544404 CDS YP_003079422.1 254794585 8218150 complement(3547367..3548032) 1 NC_013008.1 serine/threonine protein phosphatase 3548032 8218150 ECSP_3584 Escherichia coli O157:H7 str. TW14359 serine/threonine protein phosphatase YP_003079422.1 3547367 R 544404 CDS YP_003079423.1 254794586 8218151 complement(3548029..3548640) 1 NC_013008.1 hypothetical protein 3548640 8218151 ECSP_3585 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079423.1 3548029 R 544404 CDS YP_003079424.1 254794587 8218152 complement(3548615..3549181) 1 NC_013008.1 hypothetical protein 3549181 8218152 ECSP_3586 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079424.1 3548615 R 544404 CDS YP_003079425.1 254794588 8218153 3549547..3550302 1 NC_013008.1 transposase, IS30 3550302 8218153 ECSP_3587 Escherichia coli O157:H7 str. TW14359 transposase, IS30 YP_003079425.1 3549547 D 544404 CDS YP_003079426.1 254794589 8218154 3550362..3550640 1 NC_013008.1 hypothetical protein 3550640 8218154 ECSP_3588 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079426.1 3550362 D 544404 CDS YP_003079427.1 254794590 8218155 complement(3550716..3551924) 1 NC_013008.1 hypothetical protein 3551924 8218155 ECSP_3589 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079427.1 3550716 R 544404 CDS YP_003079428.1 254794591 8218156 complement(3552320..3552733) 1 NC_013008.1 hypothetical protein 3552733 8218156 ECSP_3590 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079428.1 3552320 R 544404 CDS YP_003079429.1 254794592 8218157 complement(3552831..3553052) 1 NC_013008.1 hypothetical protein 3553052 8218157 ECSP_3591 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079429.1 3552831 R 544404 CDS YP_003079430.1 254794593 8218158 complement(3553230..3554861) 1 NC_013008.1 hypothetical protein 3554861 8218158 ECSP_3592 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079430.1 3553230 R 544404 CDS YP_003079431.1 254794594 8218159 complement(3554858..3556171) 1 NC_013008.1 hypothetical protein 3556171 8218159 ECSP_3593 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079431.1 3554858 R 544404 CDS YP_003079432.1 254794595 8218160 complement(3556173..3557378) 1 NC_013008.1 hypothetical protein 3557378 8218160 ECSP_3594 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079432.1 3556173 R 544404 CDS YP_003079433.1 254794596 8218161 complement(3557701..3557907) 1 NC_013008.1 DNA binding protein 3557907 8218161 ECSP_3595 Escherichia coli O157:H7 str. TW14359 DNA binding protein YP_003079433.1 3557701 R 544404 CDS YP_003079434.1 254794597 8218162 complement(3558007..3558858) 1 NC_013008.1 hypothetical protein 3558858 8218162 ECSP_3596 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079434.1 3558007 R 544404 CDS YP_003079435.1 254794598 8218163 complement(3559285..3563871) 1 NC_013008.1 adhesin 3563871 ypjA 8218163 ypjA Escherichia coli O157:H7 str. TW14359 adhesin YP_003079435.1 3559285 R 544404 CDS YP_003079436.1 254794599 8218164 complement(3563936..3564055) 1 NC_013008.1 hypothetical protein 3564055 8218164 ECSP_3598 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079436.1 3563936 R 544404 CDS YP_003079437.1 254794600 8218165 complement(3564210..3564353) 1 NC_013008.1 hypothetical protein 3564353 8218165 ECSP_3599 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079437.1 3564210 R 544404 CDS YP_003079438.1 254794601 8218166 complement(3564807..3566156) 1 NC_013008.1 hypothetical protein 3566156 8218166 ECSP_3600 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079438.1 3564807 R 544404 CDS YP_003079439.1 254794602 8218167 complement(3566664..3566816) 1 NC_013008.1 hypothetical protein 3566816 8218167 ECSP_3601 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079439.1 3566664 R 544404 CDS YP_003079440.1 254794603 8218170 3570133..3571110 1 NC_013008.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3571110 ygaT 8218170 ygaT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079440.1 3570133 D 544404 CDS YP_003079441.1 254794604 8218171 3571130..3572398 1 NC_013008.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3572398 ygaF 8218171 ygaF Escherichia coli O157:H7 str. TW14359 hydroxyglutarate oxidase YP_003079441.1 3571130 D 544404 CDS YP_003079442.1 254794605 8218172 3572421..3573869 1 NC_013008.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3573869 gabD 8218172 gabD Escherichia coli O157:H7 str. TW14359 succinate-semialdehyde dehydrogenase I YP_003079442.1 3572421 D 544404 CDS YP_003079443.1 254794606 8218173 3573883..3575163 1 NC_013008.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3575163 gabT 8218173 gabT Escherichia coli O157:H7 str. TW14359 4-aminobutyrate aminotransferase YP_003079443.1 3573883 D 544404 CDS YP_003079444.1 254794607 8218174 3575401..3576801 1 NC_013008.1 gamma-aminobutyrate transporter 3576801 gabP 8218174 gabP Escherichia coli O157:H7 str. TW14359 gamma-aminobutyrate transporter YP_003079444.1 3575401 D 544404 CDS YP_003079445.1 254794608 8218175 3576822..3577484 1 NC_013008.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3577484 csiR 8218175 csiR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator CsiR YP_003079445.1 3576822 D 544404 CDS YP_003079446.1 254794609 8218176 complement(3577485..3577934) 1 NC_013008.1 LysM domain/BON superfamily protein 3577934 ygaU 8218176 ygaU Escherichia coli O157:H7 str. TW14359 LysM domain/BON superfamily protein YP_003079446.1 3577485 R 544404 CDS YP_003079447.1 254794610 8218177 complement(3578018..3578176) 1 NC_013008.1 hypothetical protein 3578176 yqaE 8218177 yqaE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079447.1 3578018 R 544404 CDS YP_003079448.1 254794611 8218178 3578359..3578658 1 NC_013008.1 DNA-binding transcriptional regulator 3578658 ygaV 8218178 ygaV Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079448.1 3578359 D 544404 CDS YP_003079449.1 254794612 8218179 3578668..3579186 1 NC_013008.1 inner membrane protein with hydrolase activity 3579186 ygaP 8218179 ygaP Escherichia coli O157:H7 str. TW14359 inner membrane protein with hydrolase activity YP_003079449.1 3578668 D 544404 CDS YP_003079450.1 254794613 8218180 complement(3579239..3579643) 1 NC_013008.1 DNA binding protein, nucleoid-associated 3579643 stpA 8218180 stpA Escherichia coli O157:H7 str. TW14359 DNA binding protein, nucleoid-associated YP_003079450.1 3579239 R 544404 CDS YP_003079451.1 254794614 8218181 3580057..3580185 1 NC_013008.1 hypothetical protein 3580185 8218181 ECSP_3615 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079451.1 3580057 D 544404 CDS YP_003079452.1 254794615 8218182 3580311..3580760 1 NC_013008.1 inner membrane protein 3580760 ygaW 8218182 ygaW Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079452.1 3580311 D 544404 CDS YP_003079453.1 254794616 8218183 complement(3580797..3581141) 1 NC_013008.1 hypothetical protein 3581141 ygaC 8218183 ygaC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079453.1 3580797 R 544404 CDS YP_003079454.1 254794617 8218184 3581281..3581622 1 NC_013008.1 hypothetical protein 3581622 ygaM 8218184 ygaM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079454.1 3581281 D 544404 CDS YP_003079455.1 254794618 8218185 complement(3581772..3583106) 1 NC_013008.1 hypothetical protein 3583106 8218185 ECSP_3619 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079455.1 3581772 R 544404 CDS YP_003079456.1 254794619 8218186 3583194..3583625 1 NC_013008.1 hypothetical protein 3583625 8218186 ECSP_3620 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079456.1 3583194 D 544404 CDS YP_003079457.1 254794620 8218187 3583834..3584079 1 NC_013008.1 glutaredoxin-like protein 3584079 nrdH 8218187 nrdH Escherichia coli O157:H7 str. TW14359 glutaredoxin-like protein YP_003079457.1 3583834 D 544404 CDS YP_003079458.1 254794621 8218188 3584076..3584486 1 NC_013008.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3584486 nrdI 8218188 nrdI Escherichia coli O157:H7 str. TW14359 ribonucleotide reductase stimulatory protein YP_003079458.1 3584076 D 544404 CDS YP_003079459.1 254794622 8218189 3584459..3586603 1 NC_013008.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3586603 nrdE 8218189 nrdE Escherichia coli O157:H7 str. TW14359 ribonucleotide-diphosphate reductase subunit alpha YP_003079459.1 3584459 D 544404 CDS YP_003079460.1 254794623 8218190 3586613..3587572 1 NC_013008.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3587572 nrdF 8218190 nrdF Escherichia coli O157:H7 str. TW14359 ribonucleotide-diphosphate reductase subunit beta YP_003079460.1 3586613 D 544404 CDS YP_003079461.1 254794624 8218191 3587928..3589130 1 NC_013008.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3589130 proV 8218191 proV Escherichia coli O157:H7 str. TW14359 glycine betaine transporter ATP-binding subunit YP_003079461.1 3587928 D 544404 CDS YP_003079462.1 254794625 8218192 3589123..3590187 1 NC_013008.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3590187 proW 8218192 proW Escherichia coli O157:H7 str. TW14359 glycine betaine transporter membrane protein YP_003079462.1 3589123 D 544404 CDS YP_003079463.1 254794626 8218193 3590244..3591236 1 NC_013008.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3591236 proX 8218193 proX Escherichia coli O157:H7 str. TW14359 glycine betaine transporter periplasmic subunit YP_003079463.1 3590244 D 544404 CDS YP_003079464.1 254794627 8218194 3591428..3592612 1 NC_013008.1 major facilitator superfamily transporter 3592612 8218194 ECSP_3628 Escherichia coli O157:H7 str. TW14359 major facilitator superfamily transporter YP_003079464.1 3591428 D 544404 CDS YP_003079465.1 254794628 8218195 3592736..3593473 1 NC_013008.1 transporter 3593473 ygaZ 8218195 ygaZ Escherichia coli O157:H7 str. TW14359 transporter YP_003079465.1 3592736 D 544404 CDS YP_003079466.1 254794629 8218196 3593463..3593798 1 NC_013008.1 hypothetical protein 3593798 ygaH 8218196 ygaH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079466.1 3593463 D 544404 CDS YP_003079467.1 254794630 8218197 3593889..3594419 1 NC_013008.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3594419 mprA 8218197 mprA Escherichia coli O157:H7 str. TW14359 transcriptional repressor MprA YP_003079467.1 3593889 D 544404 CDS YP_003079468.1 254794631 8218198 3594546..3595718 1 NC_013008.1 multidrug efflux system 3595718 emrA 8218198 emrA Escherichia coli O157:H7 str. TW14359 multidrug efflux system YP_003079468.1 3594546 D 544404 CDS YP_003079469.1 254794632 8218199 3595735..3597273 1 NC_013008.1 multidrug efflux system protein 3597273 emrB 8218199 emrB Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein YP_003079469.1 3595735 D 544404 CDS YP_003079470.1 254794633 8218200 complement(3597337..3597852) 1 NC_013008.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 3597852 luxS 8218200 luxS Escherichia coli O157:H7 str. TW14359 S-ribosylhomocysteinase YP_003079470.1 3597337 R 544404 CDS YP_003079471.1 254794634 8218201 complement(3598002..3599558) 1 NC_013008.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 3599558 gshA 8218201 gshA Escherichia coli O157:H7 str. TW14359 glutamate--cysteine ligase YP_003079471.1 3598002 R 544404 CDS YP_003079472.1 254794635 8218202 complement(3599631..3600059) 1 NC_013008.1 hypothetical protein 3600059 yqaA 8218202 yqaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079472.1 3599631 R 544404 CDS YP_003079473.1 254794636 8218203 complement(3600056..3600622) 1 NC_013008.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 3600622 yqaB 8218203 yqaB Escherichia coli O157:H7 str. TW14359 fructose-1-phosphatase YP_003079473.1 3600056 R 544404 CDS YP_003079474.1 254794637 8218209 complement(3601850..3602035) 1 NC_013008.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 3602035 csrA 8218209 csrA Escherichia coli O157:H7 str. TW14359 carbon storage regulator YP_003079474.1 3601850 R 544404 CDS YP_003079475.1 254794638 8218210 complement(3602270..3604900) 1 NC_013008.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 3604900 alaS 8218210 alaS Escherichia coli O157:H7 str. TW14359 alanyl-tRNA synthetase YP_003079475.1 3602270 R 544404 CDS YP_003079476.1 254794639 8218211 3604586..3604987 1 NC_013008.1 hypothetical protein 3604987 8218211 ECSP_3645 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079476.1 3604586 D 544404 CDS YP_003079477.1 254794640 8218212 complement(3605028..3605528) 1 NC_013008.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3605528 recX 8218212 recX Escherichia coli O157:H7 str. TW14359 recombination regulator RecX YP_003079477.1 3605028 R 544404 CDS YP_003079478.1 254794641 8218213 complement(3605596..3606657) 1 NC_013008.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 3606657 recA 8218213 recA Escherichia coli O157:H7 str. TW14359 recombinase A YP_003079478.1 3605596 R 544404 CDS YP_003079479.1 254794642 8218214 complement(3606737..3607234) 1 NC_013008.1 competence damage-inducible protein A 3607234 ygaD 8218214 ygaD Escherichia coli O157:H7 str. TW14359 competence damage-inducible protein A YP_003079479.1 3606737 R 544404 CDS YP_003079480.1 254794643 8218215 complement(3607379..3608464) 1 NC_013008.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 3608464 mltB 8218215 mltB Escherichia coli O157:H7 str. TW14359 murein hydrolase B YP_003079480.1 3607379 R 544404 CDS YP_003079481.1 254794644 8218218 3610250..3610621 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3610621 srlB 8218218 srlB Escherichia coli O157:H7 str. TW14359 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_003079481.1 3610250 D 544404 CDS YP_003079482.1 254794645 8218219 3610625..3611404 1 NC_013008.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3611404 srlD 8218219 srlD Escherichia coli O157:H7 str. TW14359 sorbitol-6-phosphate dehydrogenase YP_003079482.1 3610625 D 544404 CDS YP_003079483.1 254794646 8218220 3611510..3611869 1 NC_013008.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3611869 gutM 8218220 gutM Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator GutM YP_003079483.1 3611510 D 544404 CDS YP_003079484.1 254794647 8218221 3611936..3612709 1 NC_013008.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3612709 srlR 8218221 srlR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor SrlR YP_003079484.1 3611936 D 544404 CDS YP_003079485.1 254794648 8218222 3612702..3613667 1 NC_013008.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3613667 gutQ 8218222 gutQ Escherichia coli O157:H7 str. TW14359 D-arabinose 5-phosphate isomerase YP_003079485.1 3612702 D 544404 CDS YP_003079486.1 254794649 8218223 complement(3613664..3615178) 1 NC_013008.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator 3615178 norR 8218223 norR Escherichia coli O157:H7 str. TW14359 anaerobic nitric oxide reductase transcription regulator YP_003079486.1 3613664 R 544404 CDS YP_003079487.1 254794650 8218224 3615365..3616804 1 NC_013008.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3616804 norV 8218224 norV Escherichia coli O157:H7 str. TW14359 anaerobic nitric oxide reductase flavorubredoxin YP_003079487.1 3615365 D 544404 CDS YP_003079488.1 254794651 8218225 3616801..3617934 1 NC_013008.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3617934 norW 8218225 norW Escherichia coli O157:H7 str. TW14359 nitric oxide reductase YP_003079488.1 3616801 D 544404 CDS YP_003079489.1 254794652 8218226 complement(3618062..3620314) 1 NC_013008.1 carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases 3620314 hypF 8218226 hypF Escherichia coli O157:H7 str. TW14359 carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases YP_003079489.1 3618062 R 544404 CDS YP_003079490.1 254794653 8218227 complement(3620467..3620994) 1 NC_013008.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 3620994 hydN 8218227 hydN Escherichia coli O157:H7 str. TW14359 electron transport protein HydN YP_003079490.1 3620467 R 544404 CDS YP_003079491.1 254794654 8218228 complement(3621143..3622156) 1 NC_013008.1 DNA-binding transcriptional repressor 3622156 ascG 8218228 ascG Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor YP_003079491.1 3621143 R 544404 CDS YP_003079492.1 254794655 8218229 3622413..3623870 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC 3623870 ascF 8218229 ascF Escherichia coli O157:H7 str. TW14359 PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC YP_003079492.1 3622413 D 544404 CDS YP_003079493.1 254794656 8218230 3623879..3625303 1 NC_013008.1 cryptic 6-phospho-beta-glucosidase 3625303 ascB 8218230 ascB Escherichia coli O157:H7 str. TW14359 cryptic 6-phospho-beta-glucosidase YP_003079493.1 3623879 D 544404 CDS YP_003079494.1 254794657 8218231 complement(3625427..3625897) 1 NC_013008.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3625897 hycI 8218231 hycI Escherichia coli O157:H7 str. TW14359 hydrogenase 3 maturation protease YP_003079494.1 3625427 R 544404 CDS YP_003079495.1 254794658 8218232 complement(3625890..3626300) 1 NC_013008.1 protein required for maturation of hydrogenase 3 3626300 hycH 8218232 hycH Escherichia coli O157:H7 str. TW14359 protein required for maturation of hydrogenase 3 YP_003079495.1 3625890 R 544404 CDS YP_003079496.1 254794659 8218233 complement(3626297..3627064) 1 NC_013008.1 hydrogenase 3 and formate hydrogenase complex subunit HycG 3627064 hycG 8218233 hycG Escherichia coli O157:H7 str. TW14359 hydrogenase 3 and formate hydrogenase complex subunit HycG YP_003079496.1 3626297 R 544404 CDS YP_003079497.1 254794660 8218234 complement(3627064..3627606) 1 NC_013008.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3627606 hycF 8218234 hycF Escherichia coli O157:H7 str. TW14359 formate hydrogenlyase complex iron-sulfur subunit YP_003079497.1 3627064 R 544404 CDS YP_003079498.1 254794661 8218235 complement(3627616..3629325) 1 NC_013008.1 hydrogenase 3, large subunit 3629325 hycE 8218235 hycE Escherichia coli O157:H7 str. TW14359 hydrogenase 3, large subunit YP_003079498.1 3627616 R 544404 CDS YP_003079499.1 254794662 8218236 complement(3629343..3630266) 1 NC_013008.1 hydrogenase 3, membrane subunit 3630266 hycD 8218236 hycD Escherichia coli O157:H7 str. TW14359 hydrogenase 3, membrane subunit YP_003079499.1 3629343 R 544404 CDS YP_003079500.1 254794663 8218237 complement(3630269..3632095) 1 NC_013008.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3632095 hycC 8218237 hycC Escherichia coli O157:H7 str. TW14359 formate hydrogenlyase subunit 3 YP_003079500.1 3630269 R 544404 CDS YP_003079501.1 254794664 8218238 complement(3632092..3632703) 1 NC_013008.1 hydrogenase 3, Fe-S subunit 3632703 hycB 8218238 hycB Escherichia coli O157:H7 str. TW14359 hydrogenase 3, Fe-S subunit YP_003079501.1 3632092 R 544404 CDS YP_003079502.1 254794665 8218239 complement(3632828..3633289) 1 NC_013008.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3633289 hycA 8218239 hycA Escherichia coli O157:H7 str. TW14359 formate hydrogenlyase regulatory protein HycA YP_003079502.1 3632828 R 544404 CDS YP_003079503.1 254794666 8218240 complement(3633323..3633460) 1 NC_013008.1 hypothetical protein 3633460 8218240 ECSP_3674 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079503.1 3633323 R 544404 CDS YP_003079504.1 254794667 8218241 3633501..3633851 1 NC_013008.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3633851 hypA 8218241 hypA Escherichia coli O157:H7 str. TW14359 hydrogenase nickel incorporation protein YP_003079504.1 3633501 D 544404 CDS YP_003079505.1 254794668 8218242 3633855..3634727 1 NC_013008.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3634727 hypB 8218242 hypB Escherichia coli O157:H7 str. TW14359 hydrogenase nickel incorporation protein HypB YP_003079505.1 3633855 D 544404 CDS YP_003079506.1 254794669 8218243 3634718..3634990 1 NC_013008.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3634990 hypC 8218243 hypC Escherichia coli O157:H7 str. TW14359 hydrogenase assembly chaperone YP_003079506.1 3634718 D 544404 CDS YP_003079507.1 254794670 8218244 3634990..3636111 1 NC_013008.1 protein required for maturation of hydrogenases 3636111 hypD 8218244 hypD Escherichia coli O157:H7 str. TW14359 protein required for maturation of hydrogenases YP_003079507.1 3634990 D 544404 CDS YP_003079508.1 254794671 8218245 3636150..3637118 1 NC_013008.1 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 3637118 hypE 8218245 hypE Escherichia coli O157:H7 str. TW14359 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein YP_003079508.1 3636150 D 544404 CDS YP_003079509.1 254794672 8218246 3637192..3639270 1 NC_013008.1 DNA-binding transcriptional activator 3639270 fhlA 8218246 fhlA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator YP_003079509.1 3637192 D 544404 CDS YP_003079510.1 254794673 8218247 complement(3639307..3639660) 1 NC_013008.1 hypothetical protein 3639660 ygbA 8218247 ygbA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079510.1 3639307 R 544404 CDS YP_003079511.1 254794674 8218248 complement(3639737..3639871) 1 NC_013008.1 hypothetical protein 3639871 8218248 ECSP_3682 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079511.1 3639737 R 544404 CDS YP_003079512.1 254794675 8218249 3639947..3642508 1 NC_013008.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3642508 mutS 8218249 mutS Escherichia coli O157:H7 str. TW14359 DNA mismatch repair protein MutS YP_003079512.1 3639947 D 544404 CDS YP_003079513.1 254794676 8218250 3642614..3643270 1 NC_013008.1 serine/threonine-specific protein phosphatase 2 3643270 pphB 8218250 pphB Escherichia coli O157:H7 str. TW14359 serine/threonine-specific protein phosphatase 2 YP_003079513.1 3642614 D 544404 CDS YP_003079514.1 254794677 8218251 complement(3643311..3643547) 1 NC_013008.1 hypothetical protein 3643547 8218251 ECSP_3685 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079514.1 3643311 R 544404 CDS YP_003079515.1 254794678 8218252 complement(3643558..3644985) 1 NC_013008.1 hypothetical protein 3644985 8218252 ECSP_3686 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079515.1 3643558 R 544404 CDS YP_003079516.1 254794679 8218253 complement(3644985..3645578) 1 NC_013008.1 decarboxylase 3645578 8218253 ECSP_3687 Escherichia coli O157:H7 str. TW14359 decarboxylase YP_003079516.1 3644985 R 544404 CDS YP_003079517.1 254794680 8218254 3645725..3646132 1 NC_013008.1 regulator 3646132 8218254 ECSP_3688 Escherichia coli O157:H7 str. TW14359 regulator YP_003079517.1 3645725 D 544404 CDS YP_003079518.1 254794681 8218255 complement(3646252..3647244) 1 NC_013008.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3647244 rpoS 8218255 rpoS Escherichia coli O157:H7 str. TW14359 RNA polymerase sigma factor RpoS YP_003079518.1 3646252 R 544404 CDS YP_003079519.1 254794682 8218256 complement(3647307..3648398) 1 NC_013008.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3648398 nlpD 8218256 nlpD Escherichia coli O157:H7 str. TW14359 lipoprotein NlpD YP_003079519.1 3647307 R 544404 CDS YP_003079520.1 254794683 8218257 complement(3648538..3649164) 1 NC_013008.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3649164 pcm 8218257 pcm Escherichia coli O157:H7 str. TW14359 protein-L-isoaspartate O-methyltransferase YP_003079520.1 3648538 R 544404 CDS YP_003079521.1 254794684 8218258 complement(3649158..3649919) 1 NC_013008.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3649919 surE 8218258 surE Escherichia coli O157:H7 str. TW14359 stationary phase survival protein SurE YP_003079521.1 3649158 R 544404 CDS YP_003079522.1 254794685 8218259 complement(3649900..3650949) 1 NC_013008.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3650949 truD 8218259 truD Escherichia coli O157:H7 str. TW14359 tRNA pseudouridine synthase D YP_003079522.1 3649900 R 544404 CDS YP_003079523.1 254794686 8218260 complement(3650946..3651425) 1 NC_013008.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3651425 ispF 8218260 ispF Escherichia coli O157:H7 str. TW14359 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_003079523.1 3650946 R 544404 CDS YP_003079524.1 254794687 8218261 complement(3651425..3652135) 1 NC_013008.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3652135 ispD 8218261 ispD Escherichia coli O157:H7 str. TW14359 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_003079524.1 3651425 R 544404 CDS YP_003079525.1 254794688 8218262 complement(3652154..3652465) 1 NC_013008.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3652465 ftsB 8218262 ftsB Escherichia coli O157:H7 str. TW14359 cell division protein FtsB YP_003079525.1 3652154 R 544404 CDS YP_003079526.1 254794689 8218263 complement(3652659..3652982) 1 NC_013008.1 hypothetical protein 3652982 ygbE 8218263 ygbE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079526.1 3652659 R 544404 CDS YP_003079527.1 254794690 8218264 complement(3653032..3653637) 1 NC_013008.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3653637 cysC 8218264 cysC Escherichia coli O157:H7 str. TW14359 adenylylsulfate kinase YP_003079527.1 3653032 R 544404 CDS YP_003079528.1 254794691 8218265 complement(3653637..3655064) 1 NC_013008.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3655064 cysN 8218265 cysN Escherichia coli O157:H7 str. TW14359 sulfate adenylyltransferase subunit 1 YP_003079528.1 3653637 R 544404 CDS YP_003079529.1 254794692 8218266 complement(3655066..3655974) 1 NC_013008.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3655974 cysD 8218266 cysD Escherichia coli O157:H7 str. TW14359 sulfate adenylyltransferase subunit 2 YP_003079529.1 3655066 R 544404 CDS YP_003079530.1 254794693 8218267 3656226..3657263 1 NC_013008.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3657263 iap 8218267 iap Escherichia coli O157:H7 str. TW14359 alkaline phosphatase YP_003079530.1 3656226 D 544404 CDS YP_003079531.1 254794694 8218268 complement(3657653..3657946) 1 NC_013008.1 hypothetical protein 3657946 ygbF 8218268 ygbF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079531.1 3657653 R 544404 CDS YP_003079532.1 254794695 8218269 complement(3657943..3658866) 1 NC_013008.1 hypothetical protein 3658866 ygbT 8218269 ygbT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079532.1 3657943 R 544404 CDS YP_003079533.1 254794696 8218270 complement(3658863..3659513) 1 NC_013008.1 hypothetical protein 3659513 8218270 ECSP_3704 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079533.1 3658863 R 544404 CDS YP_003079534.1 254794697 8218271 complement(3659495..3660241) 1 NC_013008.1 hypothetical protein 3660241 8218271 ECSP_3705 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079534.1 3659495 R 544404 CDS YP_003079535.1 254794698 8218272 complement(3660252..3661307) 1 NC_013008.1 hypothetical protein 3661307 8218272 ECSP_3706 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079535.1 3660252 R 544404 CDS YP_003079536.1 254794699 8218273 complement(3661319..3661855) 1 NC_013008.1 hypothetical protein 3661855 8218273 ECSP_3707 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079536.1 3661319 R 544404 CDS YP_003079537.1 254794700 8218274 complement(3661852..3663414) 1 NC_013008.1 hypothetical protein 3663414 8218274 ECSP_3708 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079537.1 3661852 R 544404 CDS YP_003079538.1 254794701 8218275 complement(3663512..3666169) 1 NC_013008.1 helicase 3666169 ygcB 8218275 ygcB Escherichia coli O157:H7 str. TW14359 helicase YP_003079538.1 3663512 R 544404 CDS YP_003079539.1 254794702 8218276 complement(3666403..3666555) 1 NC_013008.1 hypothetical protein 3666555 8218276 ECSP_3710 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079539.1 3666403 R 544404 CDS YP_003079540.1 254794703 8218277 complement(3666819..3667553) 1 NC_013008.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3667553 cysH 8218277 cysH Escherichia coli O157:H7 str. TW14359 phosphoadenosine phosphosulfate reductase YP_003079540.1 3666819 R 544404 CDS YP_003079541.1 254794704 8218278 complement(3667627..3669339) 1 NC_013008.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3669339 cysI 8218278 cysI Escherichia coli O157:H7 str. TW14359 sulfite reductase subunit beta YP_003079541.1 3667627 R 544404 CDS YP_003079542.1 254794705 8218279 complement(3669339..3671138) 1 NC_013008.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3671138 cysJ 8218279 cysJ Escherichia coli O157:H7 str. TW14359 sulfite reductase subunit alpha YP_003079542.1 3669339 R 544404 CDS YP_003079543.1 254794706 8218280 3671454..3671819 1 NC_013008.1 6-pyruvoyl tetrahydrobiopterin synthase 3671819 ygcM 8218280 ygcM Escherichia coli O157:H7 str. TW14359 6-pyruvoyl tetrahydrobiopterin synthase YP_003079543.1 3671454 D 544404 CDS YP_003079544.1 254794707 8218281 3671897..3673168 1 NC_013008.1 oxidoreductase 3673168 ygcN 8218281 ygcN Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003079544.1 3671897 D 544404 CDS YP_003079545.1 254794708 8218282 3673159..3673419 1 NC_013008.1 4Fe-4S cluster-containing protein 3673419 ygcO 8218282 ygcO Escherichia coli O157:H7 str. TW14359 4Fe-4S cluster-containing protein YP_003079545.1 3673159 D 544404 CDS YP_003079546.1 254794709 8218283 3673436..3674011 1 NC_013008.1 anti-terminator regulatory protein 3674011 ygcP 8218283 ygcP Escherichia coli O157:H7 str. TW14359 anti-terminator regulatory protein YP_003079546.1 3673436 D 544404 CDS YP_003079547.1 254794710 8218285 complement(3675016..3675795) 1 NC_013008.1 flavoprotein 3675795 ygcR 8218285 ygcR Escherichia coli O157:H7 str. TW14359 flavoprotein YP_003079547.1 3675016 R 544404 CDS YP_003079548.1 254794711 8218287 complement(3677203..3678657) 1 NC_013008.1 FAD containing dehydrogenase 3678657 ygcU 8218287 ygcU Escherichia coli O157:H7 str. TW14359 FAD containing dehydrogenase YP_003079548.1 3677203 R 544404 CDS YP_003079549.1 254794712 8218288 complement(3678727..3679512) 1 NC_013008.1 deoxygluconate dehydrogenase 3679512 ygcW 8218288 ygcW Escherichia coli O157:H7 str. TW14359 deoxygluconate dehydrogenase YP_003079549.1 3678727 R 544404 CDS YP_003079550.1 254794713 8218289 3679831..3681108 1 NC_013008.1 transporter 3681108 yqcE 8218289 yqcE Escherichia coli O157:H7 str. TW14359 transporter YP_003079550.1 3679831 D 544404 CDS YP_003079551.1 254794714 8218290 3681135..3682613 1 NC_013008.1 kinase 3682613 ygcE 8218290 ygcE Escherichia coli O157:H7 str. TW14359 kinase YP_003079551.1 3681135 D 544404 CDS YP_003079553.1 254794716 8218292 complement(3683678..3684349) 1 NC_013008.1 hypothetical protein 3684349 ygcF 8218292 ygcF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079553.1 3683678 R 544404 CDS YP_003079554.1 254794717 8218293 3684630..3685124 1 NC_013008.1 LemA family protein 3685124 8218293 ECSP_3727 Escherichia coli O157:H7 str. TW14359 LemA family protein YP_003079554.1 3684630 D 544404 CDS YP_003079555.1 254794718 8218294 3685138..3685812 1 NC_013008.1 hypothetical protein 3685812 8218294 ECSP_3728 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079555.1 3685138 D 544404 CDS YP_003079556.1 254794719 8218295 3686046..3687194 1 NC_013008.1 hypothetical protein 3687194 8218295 ECSP_3729 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079556.1 3686046 D 544404 CDS YP_003079557.1 254794720 8218296 3687191..3688105 1 NC_013008.1 hypothetical protein 3688105 8218296 ECSP_3730 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079557.1 3687191 D 544404 CDS YP_003079558.1 254794721 8218297 complement(3688165..3689463) 1 NC_013008.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3689463 eno 8218297 eno Escherichia coli O157:H7 str. TW14359 phosphopyruvate hydratase YP_003079558.1 3688165 R 544404 CDS YP_003079559.1 254794722 8218298 complement(3689551..3691188) 1 NC_013008.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3691188 pyrG 8218298 pyrG Escherichia coli O157:H7 str. TW14359 CTP synthetase YP_003079559.1 3689551 R 544404 CDS YP_003079560.1 254794723 8218299 complement(3691416..3692207) 1 NC_013008.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3692207 mazG 8218299 mazG Escherichia coli O157:H7 str. TW14359 nucleoside triphosphate pyrophosphohydrolase YP_003079560.1 3691416 R 544404 CDS YP_003079561.1 254794724 8218300 complement(3692278..3692613) 1 NC_013008.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 3692613 chpA 8218300 chpA Escherichia coli O157:H7 str. TW14359 toxin ChpA YP_003079561.1 3692278 R 544404 CDS YP_003079562.1 254794725 8218301 complement(3692613..3692861) 1 NC_013008.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 3692861 chpR 8218301 chpR Escherichia coli O157:H7 str. TW14359 antitoxin MazE YP_003079562.1 3692613 R 544404 CDS YP_003079563.1 254794726 8218302 complement(3692939..3695173) 1 NC_013008.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3695173 relA 8218302 relA Escherichia coli O157:H7 str. TW14359 GDP/GTP pyrophosphokinase YP_003079563.1 3692939 R 544404 CDS YP_003079564.1 254794727 8218303 complement(3695221..3696522) 1 NC_013008.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3696522 rumA 8218303 rumA Escherichia coli O157:H7 str. TW14359 23S rRNA 5-methyluridine methyltransferase YP_003079564.1 3695221 R 544404 CDS YP_003079565.1 254794728 8218304 3696579..3699335 1 NC_013008.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3699335 barA 8218304 barA Escherichia coli O157:H7 str. TW14359 hybrid sensory histidine kinase BarA YP_003079565.1 3696579 D 544404 CDS YP_003079566.1 254794729 8218305 complement(3699568..3700908) 1 NC_013008.1 D-glucarate dehydratase 3700908 gudD 8218305 gudD Escherichia coli O157:H7 str. TW14359 D-glucarate dehydratase YP_003079566.1 3699568 R 544404 CDS YP_003079567.1 254794730 8218307 complement(3702271..3703623) 1 NC_013008.1 D-glucarate transporter 3703623 gudP 8218307 gudP Escherichia coli O157:H7 str. TW14359 D-glucarate transporter YP_003079567.1 3702271 R 544404 CDS YP_003079568.1 254794731 8218308 complement(3704058..3704507) 1 NC_013008.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3704507 yqcA 8218308 yqcA Escherichia coli O157:H7 str. TW14359 flavodoxin YP_003079568.1 3704058 R 544404 CDS YP_003079569.1 254794732 8218309 complement(3704525..3705307) 1 NC_013008.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3705307 truC 8218309 truC Escherichia coli O157:H7 str. TW14359 tRNA pseudouridine synthase C YP_003079569.1 3704525 R 544404 CDS YP_003079570.1 254794733 8218310 complement(3705307..3705636) 1 NC_013008.1 hypothetical protein 3705636 yqcC 8218310 yqcC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079570.1 3705307 R 544404 CDS YP_003079571.1 254794734 8218311 complement(3706258..3706803) 1 NC_013008.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3706803 syd 8218311 syd Escherichia coli O157:H7 str. TW14359 SecY interacting protein Syd YP_003079571.1 3706258 R 544404 CDS YP_003079572.1 254794735 8218312 3706871..3707719 1 NC_013008.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3707719 queF 8218312 queF Escherichia coli O157:H7 str. TW14359 7-cyano-7-deazaguanine reductase YP_003079572.1 3706871 D 544404 CDS YP_003079573.1 254794736 8218313 3707831..3709195 1 NC_013008.1 hypothetical protein 3709195 ygdH 8218313 ygdH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079573.1 3707831 D 544404 CDS YP_003079574.1 254794737 8218314 3709752..3711041 1 NC_013008.1 serine transporter 3711041 sdaC 8218314 sdaC Escherichia coli O157:H7 str. TW14359 serine transporter YP_003079574.1 3709752 D 544404 CDS YP_003079575.1 254794738 8218315 3711099..3712466 1 NC_013008.1 L-serine deaminase II 3712466 sdaB 8218315 sdaB Escherichia coli O157:H7 str. TW14359 L-serine deaminase II YP_003079575.1 3711099 D 544404 CDS YP_003079576.1 254794739 8218316 3712578..3713333 1 NC_013008.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3713333 xni 8218316 xni Escherichia coli O157:H7 str. TW14359 exonuclease IX YP_003079576.1 3712578 D 544404 CDS YP_003079577.1 254794740 8218317 complement(3713388..3714539) 1 NC_013008.1 L-1,2-propanediol oxidoreductase 3714539 fucO 8218317 fucO Escherichia coli O157:H7 str. TW14359 L-1,2-propanediol oxidoreductase YP_003079577.1 3713388 R 544404 CDS YP_003079578.1 254794741 8218318 complement(3714564..3715211) 1 NC_013008.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3715211 fucA 8218318 fucA Escherichia coli O157:H7 str. TW14359 L-fuculose phosphate aldolase YP_003079578.1 3714564 R 544404 CDS YP_003079579.1 254794742 8218319 3715758..3717074 1 NC_013008.1 L-fucose transporter 3717074 fucP 8218319 fucP Escherichia coli O157:H7 str. TW14359 L-fucose transporter YP_003079579.1 3715758 D 544404 CDS YP_003079580.1 254794743 8218320 3717107..3718882 1 NC_013008.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3718882 fucI 8218320 fucI Escherichia coli O157:H7 str. TW14359 L-fucose isomerase YP_003079580.1 3717107 D 544404 CDS YP_003079581.1 254794744 8218321 3718961..3720409 1 NC_013008.1 L-fuculokinase 3720409 fucK 8218321 fucK Escherichia coli O157:H7 str. TW14359 L-fuculokinase YP_003079581.1 3718961 D 544404 CDS YP_003079582.1 254794745 8218322 3720411..3720833 1 NC_013008.1 L-fucose mutarotase 3720833 fucU 8218322 fucU Escherichia coli O157:H7 str. TW14359 L-fucose mutarotase YP_003079582.1 3720411 D 544404 CDS YP_003079583.1 254794746 8218323 3720891..3721622 1 NC_013008.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3721622 fucR 8218323 fucR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator FucR YP_003079583.1 3720891 D 544404 CDS YP_003079584.1 254794747 8218324 complement(3721666..3722766) 1 NC_013008.1 RNA 2'-O-ribose methyltransferase 3722766 ygdE 8218324 ygdE Escherichia coli O157:H7 str. TW14359 RNA 2'-O-ribose methyltransferase YP_003079584.1 3721666 R 544404 CDS YP_003079585.1 254794748 8218325 complement(3722759..3723154) 1 NC_013008.1 hypothetical protein 3723154 ygdD 8218325 ygdD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079585.1 3722759 R 544404 CDS YP_003079586.1 254794749 8218326 complement(3723173..3724090) 1 NC_013008.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3724090 gcvA 8218326 gcvA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator GcvA YP_003079586.1 3723173 R 544404 CDS YP_003079587.1 254794750 8218327 complement(3724441..3724668) 1 NC_013008.1 hypothetical protein 3724668 ygdI 8218327 ygdI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079587.1 3724441 R 544404 CDS YP_003079588.1 254794751 8218328 3724860..3726065 1 NC_013008.1 cysteine sulfinate desulfinase 3726065 csdA 8218328 csdA Escherichia coli O157:H7 str. TW14359 cysteine sulfinate desulfinase YP_003079588.1 3724860 D 544404 CDS YP_003079589.1 254794752 8218329 3726065..3726508 1 NC_013008.1 Fe-S metabolism protein 3726508 ygdK 8218329 ygdK Escherichia coli O157:H7 str. TW14359 Fe-S metabolism protein YP_003079589.1 3726065 D 544404 CDS YP_003079590.1 254794753 8218330 complement(3726559..3727365) 1 NC_013008.1 hypothetical protein 3727365 ygdL 8218330 ygdL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079590.1 3726559 R 544404 CDS YP_003079591.1 254794754 8218331 complement(3727604..3728701) 1 NC_013008.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3728701 mltA 8218331 mltA Escherichia coli O157:H7 str. TW14359 murein transglycosylase A YP_003079591.1 3727604 R 544404 CDS YP_003079592.1 254794755 8218335 complement(3729280..3730533) 1 NC_013008.1 N-acetylmuramoyl-L-alanine amidase 3730533 amiC 8218335 amiC Escherichia coli O157:H7 str. TW14359 N-acetylmuramoyl-L-alanine amidase YP_003079592.1 3729280 R 544404 CDS YP_003079593.1 254794756 8218336 3730765..3732096 1 NC_013008.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3732096 argA 8218336 argA Escherichia coli O157:H7 str. TW14359 N-acetylglutamate synthase YP_003079593.1 3730765 D 544404 CDS YP_003079594.1 254794757 8218337 complement(3732158..3733984) 1 NC_013008.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3733984 recD 8218337 recD Escherichia coli O157:H7 str. TW14359 exonuclease V subunit alpha YP_003079594.1 3732158 R 544404 CDS YP_003079595.1 254794758 8218338 complement(3733984..3737526) 1 NC_013008.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3737526 recB 8218338 recB Escherichia coli O157:H7 str. TW14359 exonuclease V subunit beta YP_003079595.1 3733984 R 544404 CDS YP_003079596.1 254794759 8218339 complement(3737519..3740407) 1 NC_013008.1 protease III 3740407 ptr 8218339 ptr Escherichia coli O157:H7 str. TW14359 protease III YP_003079596.1 3737519 R 544404 CDS YP_003079597.1 254794760 8218340 complement(3740583..3743951) 1 NC_013008.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3743951 recC 8218340 recC Escherichia coli O157:H7 str. TW14359 exonuclease V subunit gamma YP_003079597.1 3740583 R 544404 CDS YP_003079598.1 254794761 8218341 complement(3743964..3744287) 1 NC_013008.1 hypothetical protein 3744287 ppdC 8218341 ppdC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079598.1 3743964 R 544404 CDS YP_003079599.1 254794762 8218342 complement(3744272..3744679) 1 NC_013008.1 hypothetical protein 3744679 ygdB 8218342 ygdB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079599.1 3744272 R 544404 CDS YP_003079600.1 254794763 8218343 complement(3744676..3745239) 1 NC_013008.1 hypothetical protein 3745239 ppdB 8218343 ppdB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079600.1 3744676 R 544404 CDS YP_003079601.1 254794764 8218344 complement(3745230..3745700) 1 NC_013008.1 hypothetical protein 3745700 ppdA 8218344 ppdA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079601.1 3745230 R 544404 CDS YP_003079602.1 254794765 8218345 complement(3745884..3746678) 1 NC_013008.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3746678 thyA 8218345 thyA Escherichia coli O157:H7 str. TW14359 thymidylate synthase YP_003079602.1 3745884 R 544404 CDS YP_003079603.1 254794766 8218346 complement(3746685..3747560) 1 NC_013008.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3747560 lgt 8218346 lgt Escherichia coli O157:H7 str. TW14359 prolipoprotein diacylglyceryl transferase YP_003079603.1 3746685 R 544404 CDS YP_003079604.1 254794767 8218347 complement(3747711..3749957) 1 NC_013008.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3749957 ptsP 8218347 ptsP Escherichia coli O157:H7 str. TW14359 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_003079604.1 3747711 R 544404 CDS YP_003079605.1 254794768 8218348 complement(3749970..3750500) 1 NC_013008.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3750500 nudH 8218348 nudH Escherichia coli O157:H7 str. TW14359 dinucleoside polyphosphate hydrolase YP_003079605.1 3749970 R 544404 CDS YP_003079606.1 254794769 8218349 complement(3750853..3750999) 1 NC_013008.1 hypothetical protein 3750999 8218349 ECSP_3783 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079606.1 3750853 R 544404 CDS YP_003079607.1 254794770 8218350 3751185..3751874 1 NC_013008.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3751874 mutH 8218350 mutH Escherichia coli O157:H7 str. TW14359 DNA mismatch repair protein YP_003079607.1 3751185 D 544404 CDS YP_003079608.1 254794771 8218351 3751943..3752656 1 NC_013008.1 inner membrane protein 3752656 ygdQ 8218351 ygdQ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079608.1 3751943 D 544404 CDS YP_003079609.1 254794772 8218352 3752794..3753012 1 NC_013008.1 hypothetical protein 3753012 ygdR 8218352 ygdR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079609.1 3752794 D 544404 CDS YP_003079610.1 254794773 8218353 3753120..3754160 1 NC_013008.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3754160 tas 8218353 tas Escherichia coli O157:H7 str. TW14359 aldo-keto reductase YP_003079610.1 3753120 D 544404 CDS YP_003079611.1 254794774 8218354 complement(3754192..3755385) 1 NC_013008.1 lysophospholipid transporter LplT 3755385 ygeD 8218354 ygeD Escherichia coli O157:H7 str. TW14359 lysophospholipid transporter LplT YP_003079611.1 3754192 R 544404 CDS YP_003079612.1 254794775 8218355 complement(3755378..3757537) 1 NC_013008.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3757537 aas 8218355 aas Escherichia coli O157:H7 str. TW14359 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_003079612.1 3755378 R 544404 CDS YP_003079613.1 254794776 8218356 3758123..3759154 1 NC_013008.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3759154 galR 8218356 galR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator GalR YP_003079613.1 3758123 D 544404 CDS YP_003079614.1 254794777 8218357 complement(3759161..3760423) 1 NC_013008.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3760423 lysA 8218357 lysA Escherichia coli O157:H7 str. TW14359 diaminopimelate decarboxylase YP_003079614.1 3759161 R 544404 CDS YP_003079615.1 254794778 8218358 3760545..3761480 1 NC_013008.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3761480 lysR 8218358 lysR Escherichia coli O157:H7 str. TW14359 LysR family transcriptional regulator YP_003079615.1 3760545 D 544404 CDS YP_003079616.1 254794779 8218359 complement(3761467..3762159) 1 NC_013008.1 racemase 3762159 ygeA 8218359 ygeA Escherichia coli O157:H7 str. TW14359 racemase YP_003079616.1 3761467 R 544404 CDS YP_003079617.1 254794780 8218360 complement(3762288..3763706) 1 NC_013008.1 arabinose transporter 3763706 araE 8218360 araE Escherichia coli O157:H7 str. TW14359 arabinose transporter YP_003079617.1 3762288 R 544404 CDS YP_003079618.1 254794781 8218361 complement(3764021..3764782) 1 NC_013008.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3764782 kduD 8218361 kduD Escherichia coli O157:H7 str. TW14359 2-deoxy-D-gluconate 3-dehydrogenase YP_003079618.1 3764021 R 544404 CDS YP_003079619.1 254794782 8218362 complement(3764812..3765648) 1 NC_013008.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3765648 kduI 8218362 kduI Escherichia coli O157:H7 str. TW14359 5-keto-4-deoxyuronate isomerase YP_003079619.1 3764812 R 544404 CDS YP_003079620.1 254794783 8218363 complement(3765935..3767116) 1 NC_013008.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3767116 yqeF 8218363 yqeF Escherichia coli O157:H7 str. TW14359 acetyl-CoA acetyltransferase YP_003079620.1 3765935 R 544404 CDS YP_003079621.1 254794784 8218364 3767371..3768600 1 NC_013008.1 transporter 3768600 yqeG 8218364 yqeG Escherichia coli O157:H7 str. TW14359 transporter YP_003079621.1 3767371 D 544404 CDS YP_003079622.1 254794785 8218365 3769060..3769692 1 NC_013008.1 hypothetical protein 3769692 yqeH 8218365 yqeH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079622.1 3769060 D 544404 CDS YP_003079623.1 254794786 8218366 3770026..3770835 1 NC_013008.1 transcriptional regulator 3770835 yqeI 8218366 yqeI Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003079623.1 3770026 D 544404 CDS YP_003079624.1 254794787 8218367 3770832..3771311 1 NC_013008.1 hypothetical protein 3771311 yqeJ 8218367 yqeJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079624.1 3770832 D 544404 CDS YP_003079625.1 254794788 8218368 complement(3771460..3771885) 1 NC_013008.1 hypothetical protein 3771885 yqeK 8218368 yqeK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079625.1 3771460 R 544404 CDS YP_003079626.1 254794789 8218369 complement(3772025..3772261) 1 NC_013008.1 hypothetical protein 3772261 8218369 ECSP_3803 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079626.1 3772025 R 544404 CDS YP_003079627.1 254794790 8218370 3772315..3772806 1 NC_013008.1 hypothetical protein 3772806 ygeF 8218370 ygeF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079627.1 3772315 D 544404 CDS YP_003079628.1 254794791 8218371 3773032..3773523 1 NC_013008.1 chaperone 3773523 ygeG 8218371 ygeG Escherichia coli O157:H7 str. TW14359 chaperone YP_003079628.1 3773032 D 544404 CDS YP_003079629.1 254794792 8218372 3773857..3775233 1 NC_013008.1 transcriptional regulator 3775233 ygeH 8218372 ygeH Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003079629.1 3773857 D 544404 CDS YP_003079630.1 254794793 8218373 3775400..3775618 1 NC_013008.1 hypothetical protein 3775618 ygeI 8218373 ygeI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079630.1 3775400 D 544404 CDS YP_003079631.1 254794794 8218374 3775703..3776206 1 NC_013008.1 lytic transglycosylase 3776206 pbl 8218374 pbl Escherichia coli O157:H7 str. TW14359 lytic transglycosylase YP_003079631.1 3775703 D 544404 CDS YP_003079632.1 254794795 8218375 complement(3776225..3776857) 1 NC_013008.1 2-component transcriptional regulator 3776857 8218375 ECSP_3809 Escherichia coli O157:H7 str. TW14359 2-component transcriptional regulator YP_003079632.1 3776225 R 544404 CDS YP_003079633.1 254794796 8218376 complement(3776836..3777003) 1 NC_013008.1 hypothetical protein 3777003 8218376 ECSP_3810 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079633.1 3776836 R 544404 CDS YP_003079634.1 254794797 8218377 complement(3777080..3777511) 1 NC_013008.1 hypothetical protein 3777511 8218377 ECSP_3811 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079634.1 3777080 R 544404 CDS YP_003079635.1 254794798 8218378 complement(3777528..3777788) 1 NC_013008.1 hypothetical protein 3777788 8218378 ECSP_3812 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079635.1 3777528 R 544404 CDS YP_003079636.1 254794799 8218379 complement(3777730..3778311) 1 NC_013008.1 hypothetical protein 3778311 ygeO 8218379 ygeO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079636.1 3777730 R 544404 CDS YP_003079637.1 254794800 8218380 complement(3778327..3779061) 1 NC_013008.1 lipoprotein of type III secretion apparatus 3779061 eprK 8218380 eprK Escherichia coli O157:H7 str. TW14359 lipoprotein of type III secretion apparatus YP_003079637.1 3778327 R 544404 CDS YP_003079638.1 254794801 8218381 complement(3779058..3779390) 1 NC_013008.1 Type III secretion apparatus protein 3779390 eprJ 8218381 eprJ Escherichia coli O157:H7 str. TW14359 Type III secretion apparatus protein YP_003079638.1 3779058 R 544404 CDS YP_003079639.1 254794802 8218382 complement(3779410..3779649) 1 NC_013008.1 type III secretion apparatus protein EprI 3779649 eprI 8218382 eprI Escherichia coli O157:H7 str. TW14359 type III secretion apparatus protein EprI YP_003079639.1 3779410 R 544404 CDS YP_003079640.1 254794803 8218384 3781101..3781601 1 NC_013008.1 hypothetical protein 3781601 8218384 ECSP_3818 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079640.1 3781101 D 544404 CDS YP_003079641.1 254794804 8218385 complement(3781958..3783079) 1 NC_013008.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; surface presentation of antigens protein SpaS 3783079 epaS 8218385 epaS Escherichia coli O157:H7 str. TW14359 surface presentation of antigens protein SpaS YP_003079641.1 3781958 R 544404 CDS YP_003079642.1 254794805 8218387 complement(3783857..3784117) 1 NC_013008.1 type III secretion apparatus protein 3784117 epaQ 8218387 epaQ Escherichia coli O157:H7 str. TW14359 type III secretion apparatus protein YP_003079642.1 3783857 R 544404 CDS YP_003079643.1 254794806 8218388 complement(3784128..3784793) 1 NC_013008.1 part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP 3784793 spaP 8218388 spaP Escherichia coli O157:H7 str. TW14359 surface presentation of antigens protein SpaP YP_003079643.1 3784128 R 544404 CDS YP_003079644.1 254794807 8218389 complement(3784783..3785769) 1 NC_013008.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; surface presentation of antigens protein SpaO 3785769 epaO 8218389 epaO Escherichia coli O157:H7 str. TW14359 surface presentation of antigens protein SpaO YP_003079644.1 3784783 R 544404 CDS YP_003079645.1 254794808 8218390 complement(3785729..3786298) 1 NC_013008.1 type III secretion apparatus protein 3786298 eivJ 8218390 eivJ Escherichia coli O157:H7 str. TW14359 type III secretion apparatus protein YP_003079645.1 3785729 R 544404 CDS YP_003079646.1 254794809 8218391 complement(3786371..3786604) 1 NC_013008.1 hypothetical protein 3786604 8218391 ECSP_3825 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079646.1 3786371 R 544404 CDS YP_003079647.1 254794810 8218392 complement(3786582..3786917) 1 NC_013008.1 type III secretion apparatus protein 3786917 eivI 8218392 eivI Escherichia coli O157:H7 str. TW14359 type III secretion apparatus protein YP_003079647.1 3786582 R 544404 CDS YP_003079648.1 254794811 8218393 complement(3787030..3788349) 1 NC_013008.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase; ATP synthase SpaL 3788349 eivC 8218393 eivC Escherichia coli O157:H7 str. TW14359 ATP synthase SpaL YP_003079648.1 3787030 R 544404 CDS YP_003079649.1 254794812 8218394 complement(3788354..3790414) 1 NC_013008.1 type III secretion apparatus protein 3790414 eivA 8218394 eivA Escherichia coli O157:H7 str. TW14359 type III secretion apparatus protein YP_003079649.1 3788354 R 544404 CDS YP_003079650.1 254794813 8218395 complement(3790407..3791552) 1 NC_013008.1 hypothetical protein 3791552 eivE 8218395 eivE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079650.1 3790407 R 544404 CDS YP_003079651.1 254794814 8218396 complement(3791557..3793260) 1 NC_013008.1 type III secretion apparatus protein 3793260 eivG 8218396 eivG Escherichia coli O157:H7 str. TW14359 type III secretion apparatus protein YP_003079651.1 3791557 R 544404 CDS YP_003079652.1 254794815 8218397 complement(3793257..3794006) 1 NC_013008.1 regulatory protein for type III secretion apparatus 3794006 eivF 8218397 eivF Escherichia coli O157:H7 str. TW14359 regulatory protein for type III secretion apparatus YP_003079652.1 3793257 R 544404 CDS YP_003079653.1 254794816 8218398 complement(3794352..3794531) 1 NC_013008.1 hypothetical protein 3794531 8218398 ECSP_3832 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079653.1 3794352 R 544404 CDS YP_003079654.1 254794817 8218401 complement(3796589..3797344) 1 NC_013008.1 hypothetical protein 3797344 ygeR 8218401 ygeR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079654.1 3796589 R 544404 CDS YP_003079655.1 254794818 8218402 3797799..3800057 1 NC_013008.1 molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3800057 xdhA 8218402 xdhA Escherichia coli O157:H7 str. TW14359 xanthine dehydrogenase subunit XdhA YP_003079655.1 3797799 D 544404 CDS YP_003079656.1 254794819 8218403 3800068..3800946 1 NC_013008.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3800946 xdhB 8218403 xdhB Escherichia coli O157:H7 str. TW14359 xanthine dehydrogenase subunit XdhB YP_003079656.1 3800068 D 544404 CDS YP_003079657.1 254794820 8218404 3800943..3801422 1 NC_013008.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3801422 xdhC 8218404 xdhC Escherichia coli O157:H7 str. TW14359 xanthine dehydrogenase subunit XdhC YP_003079657.1 3800943 D 544404 CDS YP_003079658.1 254794821 8218405 complement(3801462..3803240) 1 NC_013008.1 DNA-binding transcriptional regulator 3803240 ygeV 8218405 ygeV Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079658.1 3801462 R 544404 CDS YP_003079659.1 254794822 8218406 3803716..3804906 1 NC_013008.1 aspartate/ornithine carbamoyltransferase 3804906 ygeW 8218406 ygeW Escherichia coli O157:H7 str. TW14359 aspartate/ornithine carbamoyltransferase YP_003079659.1 3803716 D 544404 CDS YP_003079660.1 254794823 8218407 3804964..3806160 1 NC_013008.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3806160 ygeX 8218407 ygeX Escherichia coli O157:H7 str. TW14359 diaminopropionate ammonia-lyase YP_003079660.1 3804964 D 544404 CDS YP_003079661.1 254794824 8218408 3806218..3807429 1 NC_013008.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3807429 ygeY 8218408 ygeY Escherichia coli O157:H7 str. TW14359 peptidase YP_003079661.1 3806218 D 544404 CDS YP_003079662.1 254794825 8218409 3807482..3808867 1 NC_013008.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3808867 hyuA 8218409 hyuA Escherichia coli O157:H7 str. TW14359 phenylhydantoinase YP_003079662.1 3807482 D 544404 CDS YP_003079663.1 254794826 8218410 3808915..3809847 1 NC_013008.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3809847 yqeA 8218410 yqeA Escherichia coli O157:H7 str. TW14359 carbamate kinase YP_003079663.1 3808915 D 544404 CDS YP_003079664.1 254794827 8218411 complement(3809888..3811513) 1 NC_013008.1 hypothetical protein 3811513 yqeB 8218411 yqeB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079664.1 3809888 R 544404 CDS YP_003079665.1 254794828 8218412 complement(3811561..3812331) 1 NC_013008.1 hypothetical protein 3812331 yqeC 8218412 yqeC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079665.1 3811561 R 544404 CDS YP_003079666.1 254794829 8218413 3812434..3813012 1 NC_013008.1 hypothetical protein 3813012 ygfJ 8218413 ygfJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079666.1 3812434 D 544404 CDS YP_003079667.1 254794830 8218414 3813334..3816432 1 NC_013008.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3816432 ygfK 8218414 ygfK Escherichia coli O157:H7 str. TW14359 selenate reductase subunit YgfK YP_003079667.1 3813334 D 544404 CDS YP_003079668.1 254794831 8218415 3816435..3817763 1 NC_013008.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3817763 ssnA 8218415 ssnA Escherichia coli O157:H7 str. TW14359 chlorohydrolase/aminohydrolase YP_003079668.1 3816435 D 544404 CDS YP_003079669.1 254794832 8218416 3817813..3818592 1 NC_013008.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3818592 ygfM 8218416 ygfM Escherichia coli O157:H7 str. TW14359 selenate reductase subunit YgfM YP_003079669.1 3817813 D 544404 CDS YP_003079670.1 254794833 8218417 3818589..3821459 1 NC_013008.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3821459 xdhD 8218417 xdhD Escherichia coli O157:H7 str. TW14359 selenate reductase subunit YgfN YP_003079670.1 3818589 D 544404 CDS YP_003079671.1 254794834 8218418 3821624..3823024 1 NC_013008.1 transporter 3823024 ygfO 8218418 ygfO Escherichia coli O157:H7 str. TW14359 transporter YP_003079671.1 3821624 D 544404 CDS YP_003079672.1 254794835 8218419 3823039..3824358 1 NC_013008.1 Catalyzes the deamination of guanine; guanine deaminase 3824358 guaD 8218419 guaD Escherichia coli O157:H7 str. TW14359 guanine deaminase YP_003079672.1 3823039 D 544404 CDS YP_003079673.1 254794836 8218420 3824394..3825761 1 NC_013008.1 transporter 3825761 ygfQ 8218420 ygfQ Escherichia coli O157:H7 str. TW14359 transporter YP_003079673.1 3824394 D 544404 CDS YP_003079674.1 254794837 8218421 complement(3825797..3826192) 1 NC_013008.1 oxidoreductase 3826192 ygfS 8218421 ygfS Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003079674.1 3825797 R 544404 CDS YP_003079675.1 254794838 8218422 complement(3826285..3828204) 1 NC_013008.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3828204 ygfT 8218422 ygfT Escherichia coli O157:H7 str. TW14359 oxidoreductase Fe-S binding subunit YP_003079675.1 3826285 R 544404 CDS YP_003079676.1 254794839 8218423 3828640..3830088 1 NC_013008.1 transporter 3830088 ygfU 8218423 ygfU Escherichia coli O157:H7 str. TW14359 transporter YP_003079676.1 3828640 D 544404 CDS YP_003079677.1 254794840 8218424 3830338..3830886 1 NC_013008.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3830886 idi 8218424 idi Escherichia coli O157:H7 str. TW14359 isopentenyl-diphosphate delta-isomerase YP_003079677.1 3830338 D 544404 CDS YP_003079678.1 254794841 8218425 complement(3830929..3832446) 1 NC_013008.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3832446 lysS 8218425 lysS Escherichia coli O157:H7 str. TW14359 lysyl-tRNA synthetase YP_003079678.1 3830929 R 544404 CDS YP_003079679.1 254794842 8218426 complement(3833645..3835378) 1 NC_013008.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3835378 recJ 8218426 recJ Escherichia coli O157:H7 str. TW14359 ssDNA exonuclease RecJ YP_003079679.1 3833645 R 544404 CDS YP_003079680.1 254794843 8218427 complement(3835384..3836094) 1 NC_013008.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3836094 dsbC 8218427 dsbC Escherichia coli O157:H7 str. TW14359 thiol:disulfide interchange protein DsbC YP_003079680.1 3835384 R 544404 CDS YP_003079681.1 254794844 8218428 complement(3836119..3837015) 1 NC_013008.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3837015 xerD 8218428 xerD Escherichia coli O157:H7 str. TW14359 site-specific tyrosine recombinase XerD YP_003079681.1 3836119 R 544404 CDS YP_003079682.1 254794845 8218429 3837127..3837648 1 NC_013008.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3837648 fldB 8218429 fldB Escherichia coli O157:H7 str. TW14359 flavodoxin FldB YP_003079682.1 3837127 D 544404 CDS YP_003079683.1 254794846 8218430 complement(3837688..3838095) 1 NC_013008.1 hypothetical protein 3838095 ygfX 8218430 ygfX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079683.1 3837688 R 544404 CDS YP_003079684.1 254794847 8218431 complement(3838076..3838342) 1 NC_013008.1 hypothetical protein 3838342 ygfY 8218431 ygfY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079684.1 3838076 R 544404 CDS YP_003079685.1 254794848 8218432 3838585..3839565 1 NC_013008.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3839565 ygfZ 8218432 ygfZ Escherichia coli O157:H7 str. TW14359 global regulator YP_003079685.1 3838585 D 544404 CDS YP_003079686.1 254794849 8218433 complement(3839642..3840301) 1 NC_013008.1 oxidoreductase 3840301 yqfA 8218433 yqfA Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003079686.1 3839642 R 544404 CDS YP_003079687.1 254794850 8218434 complement(3840465..3840776) 1 NC_013008.1 hypothetical protein 3840776 yqfB 8218434 yqfB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079687.1 3840465 R 544404 CDS YP_003079688.1 254794851 8218435 3840815..3842254 1 NC_013008.1 6-phospho-beta-glucosidase 3842254 bglA 8218435 bglA Escherichia coli O157:H7 str. TW14359 6-phospho-beta-glucosidase YP_003079688.1 3840815 D 544404 CDS YP_003079689.1 254794852 8218436 complement(3842420..3845293) 1 NC_013008.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3845293 gcvP 8218436 gcvP Escherichia coli O157:H7 str. TW14359 glycine dehydrogenase YP_003079689.1 3842420 R 544404 CDS YP_003079690.1 254794853 8218437 complement(3845411..3845800) 1 NC_013008.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3845800 gcvH 8218437 gcvH Escherichia coli O157:H7 str. TW14359 glycine cleavage system protein H YP_003079690.1 3845411 R 544404 CDS YP_003079691.1 254794854 8218438 complement(3845824..3846918) 1 NC_013008.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3846918 gcvT 8218438 gcvT Escherichia coli O157:H7 str. TW14359 glycine cleavage system aminomethyltransferase T YP_003079691.1 3845824 R 544404 CDS YP_003079692.1 254794855 8218439 complement(3847366..3848568) 1 NC_013008.1 hypothetical protein 3848568 visC 8218439 visC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079692.1 3847366 R 544404 CDS YP_003079693.1 254794856 8218440 complement(3848592..3849770) 1 NC_013008.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3849770 ubiH 8218440 ubiH Escherichia coli O157:H7 str. TW14359 2-octaprenyl-6-methoxyphenyl hydroxylase YP_003079693.1 3848592 R 544404 CDS YP_003079694.1 254794857 8218441 complement(3849767..3851092) 1 NC_013008.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3851092 pepP 8218441 pepP Escherichia coli O157:H7 str. TW14359 proline aminopeptidase P II YP_003079694.1 3849767 R 544404 CDS YP_003079695.1 254794858 8218442 complement(3851118..3851696) 1 NC_013008.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3851696 ygfB 8218442 ygfB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079695.1 3851118 R 544404 CDS YP_003079696.1 254794859 8218443 3851864..3852193 1 NC_013008.1 Z-ring-associated protein 3852193 zapA 8218443 zapA Escherichia coli O157:H7 str. TW14359 Z-ring-associated protein YP_003079696.1 3851864 D 544404 CDS YP_003079697.1 254794860 8218444 3852493..3853041 1 NC_013008.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3853041 ygfA 8218444 ygfA Escherichia coli O157:H7 str. TW14359 ligase YP_003079697.1 3852493 D 544404 CDS YP_003079699.1 254794862 8218446 complement(3853823..3855055) 1 NC_013008.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3855055 serA 8218446 serA Escherichia coli O157:H7 str. TW14359 D-3-phosphoglycerate dehydrogenase YP_003079699.1 3853823 R 544404 CDS YP_003079700.1 254794863 8218447 complement(3855310..3855969) 1 NC_013008.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3855969 rpiA 8218447 rpiA Escherichia coli O157:H7 str. TW14359 ribose-5-phosphate isomerase A YP_003079700.1 3855310 R 544404 CDS YP_003079701.1 254794864 8218448 3856352..3857245 1 NC_013008.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3857245 argP 8218448 argP Escherichia coli O157:H7 str. TW14359 chromosome replication initiation inhibitor protein YP_003079701.1 3856352 D 544404 CDS YP_003079702.1 254794865 8218449 3857449..3859593 1 NC_013008.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3859593 sbm 8218449 sbm Escherichia coli O157:H7 str. TW14359 methylmalonyl-CoA mutase YP_003079702.1 3857449 D 544404 CDS YP_003079703.1 254794866 8218450 3859586..3860581 1 NC_013008.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3860581 argK 8218450 argK Escherichia coli O157:H7 str. TW14359 arginine/ornithine transport system ATPase YP_003079703.1 3859586 D 544404 CDS YP_003079704.1 254794867 8218451 3860592..3861377 1 NC_013008.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3861377 ygfG 8218451 ygfG Escherichia coli O157:H7 str. TW14359 methylmalonyl-CoA decarboxylase YP_003079704.1 3860592 D 544404 CDS YP_003079705.1 254794868 8218452 3861401..3862879 1 NC_013008.1 propionyl-CoA:succinate-CoA transferase 3862879 ygfH 8218452 ygfH Escherichia coli O157:H7 str. TW14359 propionyl-CoA:succinate-CoA transferase YP_003079705.1 3861401 D 544404 CDS YP_003079706.1 254794869 8218454 complement(3863939..3864679) 1 NC_013008.1 hypothetical protein 3864679 yggE 8218454 yggE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079706.1 3863939 R 544404 CDS YP_003079707.1 254794870 8218455 complement(3864772..3865407) 1 NC_013008.1 Involved in the export of arginine; arginine exporter protein 3865407 argO 8218455 argO Escherichia coli O157:H7 str. TW14359 arginine exporter protein YP_003079707.1 3864772 R 544404 CDS YP_003079708.1 254794871 8218456 complement(3865546..3866406) 1 NC_013008.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3866406 mscS 8218456 mscS Escherichia coli O157:H7 str. TW14359 mechanosensitive channel MscS YP_003079708.1 3865546 R 544404 CDS YP_003079709.1 254794872 8218457 complement(3866764..3867843) 1 NC_013008.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3867843 fbaA 8218457 fbaA Escherichia coli O157:H7 str. TW14359 fructose-bisphosphate aldolase YP_003079709.1 3866764 R 544404 CDS YP_003079710.1 254794873 8218458 complement(3868058..3869221) 1 NC_013008.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3869221 pgk 8218458 pgk Escherichia coli O157:H7 str. TW14359 phosphoglycerate kinase YP_003079710.1 3868058 R 544404 CDS YP_003079711.1 254794874 8218459 complement(3869271..3870290) 1 NC_013008.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3870290 epd 8218459 epd Escherichia coli O157:H7 str. TW14359 erythrose 4-phosphate dehydrogenase YP_003079711.1 3869271 R 544404 CDS YP_003079712.1 254794875 8218460 3870662..3871093 1 NC_013008.1 hypothetical protein 3871093 8218460 ECSP_3894 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079712.1 3870662 D 544404 CDS YP_003079713.1 254794876 8218461 3871116..3871694 1 NC_013008.1 hypothetical protein 3871694 8218461 ECSP_3895 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079713.1 3871116 D 544404 CDS YP_003079714.1 254794877 8218462 3871695..3872402 1 NC_013008.1 hypothetical protein 3872402 8218462 ECSP_3896 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079714.1 3871695 D 544404 CDS YP_003079715.1 254794878 8218463 3872390..3873067 1 NC_013008.1 ATP-binding protein of ABC transport system 3873067 8218463 ECSP_3897 Escherichia coli O157:H7 str. TW14359 ATP-binding protein of ABC transport system YP_003079715.1 3872390 D 544404 CDS YP_003079716.1 254794879 8218464 3873061..3873738 1 NC_013008.1 ATP-binding protein of ABC transport system 3873738 8218464 ECSP_3898 Escherichia coli O157:H7 str. TW14359 ATP-binding protein of ABC transport system YP_003079716.1 3873061 D 544404 CDS YP_003079717.1 254794880 8218465 complement(3873710..3874423) 1 NC_013008.1 fructose transport system kinase 3874423 frcK 8218465 frcK Escherichia coli O157:H7 str. TW14359 fructose transport system kinase YP_003079717.1 3873710 R 544404 CDS YP_003079718.1 254794881 8218466 complement(3874420..3874929) 1 NC_013008.1 DNA-binding transcriptional regulator 3874929 yggD 8218466 yggD Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079718.1 3874420 R 544404 CDS YP_003079719.1 254794882 8218467 complement(3874951..3875916) 1 NC_013008.1 fructose-1,6-bisphosphatase II-like protein 3875916 yggF 8218467 yggF Escherichia coli O157:H7 str. TW14359 fructose-1,6-bisphosphatase II-like protein YP_003079719.1 3874951 R 544404 CDS YP_003079720.1 254794883 8218468 complement(3875913..3877190) 1 NC_013008.1 dehydrogenase 3877190 yggP 8218468 yggP Escherichia coli O157:H7 str. TW14359 dehydrogenase YP_003079720.1 3875913 R 544404 CDS YP_003079721.1 254794884 8218469 complement(3877205..3878593) 1 NC_013008.1 fused mannitol-specific PTS enzymes: IIB component, IIC component 3878593 cmtA 8218469 cmtA Escherichia coli O157:H7 str. TW14359 fused mannitol-specific PTS enzymes: IIB component, IIC component YP_003079721.1 3877205 R 544404 CDS YP_003079722.1 254794885 8218470 complement(3878621..3879064) 1 NC_013008.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3879064 cmtB 8218470 cmtB Escherichia coli O157:H7 str. TW14359 mannitol phosphotransferase subunit EIIA YP_003079722.1 3878621 R 544404 CDS YP_003079723.1 254794886 8218471 complement(3879378..3881369) 1 NC_013008.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3881369 tktA 8218471 tktA Escherichia coli O157:H7 str. TW14359 transketolase YP_003079723.1 3879378 R 544404 CDS YP_003079724.1 254794887 8218472 3881647..3882405 1 NC_013008.1 peptidase 3882405 yggG 8218472 yggG Escherichia coli O157:H7 str. TW14359 peptidase YP_003079724.1 3881647 D 544404 CDS YP_003079725.1 254794888 8218473 complement(3882611..3883531) 1 NC_013008.1 catalyzes the formation of putrescine from agmatine; agmatinase 3883531 speB 8218473 speB Escherichia coli O157:H7 str. TW14359 agmatinase YP_003079725.1 3882611 R 544404 CDS YP_003079726.1 254794889 8218474 complement(3883667..3884398) 1 NC_013008.1 hypothetical protein 3884398 8218474 ECSP_3908 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079726.1 3883667 R 544404 CDS YP_003079727.1 254794890 8218475 complement(3884544..3886520) 1 NC_013008.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3886520 speA 8218475 speA Escherichia coli O157:H7 str. TW14359 arginine decarboxylase YP_003079727.1 3884544 R 544404 CDS YP_003079728.1 254794891 8218476 complement(3886529..3886660) 1 NC_013008.1 hypothetical protein 3886660 yqgB 8218476 yqgB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079728.1 3886529 R 544404 CDS YP_003079729.1 254794892 8218477 3886796..3887011 1 NC_013008.1 hypothetical protein 3887011 yqgC 8218477 yqgC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079729.1 3886796 D 544404 CDS YP_003079730.1 254794893 8218478 complement(3887008..3887259) 1 NC_013008.1 inner membrane protein 3887259 yqgD 8218478 yqgD Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079730.1 3887008 R 544404 CDS YP_003079731.1 254794894 8218479 3887315..3888469 1 NC_013008.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3888469 metK 8218479 metK Escherichia coli O157:H7 str. TW14359 S-adenosylmethionine synthetase YP_003079731.1 3887315 D 544404 CDS YP_003079732.1 254794895 8218480 3888906..3890300 1 NC_013008.1 D-galactose transporter 3890300 galP 8218480 galP Escherichia coli O157:H7 str. TW14359 D-galactose transporter YP_003079732.1 3888906 D 544404 CDS YP_003079733.1 254794896 8218481 3890377..3890874 1 NC_013008.1 hypothetical protein 3890874 sprT 8218481 sprT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079733.1 3890377 D 544404 CDS YP_003079734.1 254794897 8218482 3890969..3891676 1 NC_013008.1 DNase I 3891676 endA 8218482 endA Escherichia coli O157:H7 str. TW14359 DNase I YP_003079734.1 3890969 D 544404 CDS YP_003079735.1 254794898 8218483 3891756..3892487 1 NC_013008.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3892487 yggJ 8218483 yggJ Escherichia coli O157:H7 str. TW14359 16S ribosomal RNA methyltransferase RsmE YP_003079735.1 3891756 D 544404 CDS YP_003079736.1 254794899 8218484 3892500..3893447 1 NC_013008.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3893447 gshB 8218484 gshB Escherichia coli O157:H7 str. TW14359 glutathione synthetase YP_003079736.1 3892500 D 544404 CDS YP_003079737.1 254794900 8218485 3893559..3894122 1 NC_013008.1 hypothetical protein 3894122 yqgE 8218485 yqgE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079737.1 3893559 D 544404 CDS YP_003079738.1 254794901 8218486 3894122..3894538 1 NC_013008.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3894538 yqgF 8218486 yqgF Escherichia coli O157:H7 str. TW14359 Holliday junction resolvase-like protein YP_003079738.1 3894122 D 544404 CDS YP_003079739.1 254794902 8218487 complement(3894729..3895709) 1 NC_013008.1 transporter 3895709 yggR 8218487 yggR Escherichia coli O157:H7 str. TW14359 transporter YP_003079739.1 3894729 R 544404 CDS YP_003079740.1 254794903 8218488 3895727..3896431 1 NC_013008.1 hypothetical protein 3896431 yggS 8218488 yggS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079740.1 3895727 D 544404 CDS YP_003079741.1 254794904 8218489 3896449..3897015 1 NC_013008.1 inner membrane protein 3897015 yggT 8218489 yggT Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079741.1 3896449 D 544404 CDS YP_003079742.1 254794905 8218490 3897012..3897302 1 NC_013008.1 hypothetical protein 3897302 yggU 8218490 yggU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079742.1 3897012 D 544404 CDS YP_003079743.1 254794906 8218491 3897310..3897903 1 NC_013008.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3897903 yggV 8218491 yggV Escherichia coli O157:H7 str. TW14359 deoxyribonucleotide triphosphate pyrophosphatase YP_003079743.1 3897310 D 544404 CDS YP_003079744.1 254794907 8218492 3897896..3899032 1 NC_013008.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3899032 yggW 8218492 yggW Escherichia coli O157:H7 str. TW14359 coproporphyrinogen III oxidase YP_003079744.1 3897896 D 544404 CDS YP_003079745.1 254794908 8218493 complement(3899275..3900282) 1 NC_013008.1 hypothetical protein 3900282 yggM 8218493 yggM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079745.1 3899275 R 544404 CDS YP_003079746.1 254794909 8218494 complement(3900399..3901445) 1 NC_013008.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3901445 ansB 8218494 ansB Escherichia coli O157:H7 str. TW14359 L-asparaginase II YP_003079746.1 3900399 R 544404 CDS YP_003079747.1 254794910 8218495 complement(3901621..3902340) 1 NC_013008.1 hypothetical protein 3902340 yggN 8218495 yggN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079747.1 3901621 R 544404 CDS YP_003079748.1 254794911 8218496 complement(3902361..3902501) 1 NC_013008.1 hypothetical protein 3902501 8218496 ECSP_3930 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079748.1 3902361 R 544404 CDS YP_003079749.1 254794912 8218497 complement(3902524..3902850) 1 NC_013008.1 hypothetical protein 3902850 yggL 8218497 yggL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079749.1 3902524 R 544404 CDS YP_003079750.1 254794913 8218498 complement(3902850..3903569) 1 NC_013008.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3903569 trmB 8218498 trmB Escherichia coli O157:H7 str. TW14359 tRNA (guanine-N(7)-)-methyltransferase YP_003079750.1 3902850 R 544404 CDS YP_003079751.1 254794914 8218499 3903730..3904782 1 NC_013008.1 adenine DNA glycosylase 3904782 mutY 8218499 mutY Escherichia coli O157:H7 str. TW14359 adenine DNA glycosylase YP_003079751.1 3903730 D 544404 CDS YP_003079752.1 254794915 8218500 3904810..3905085 1 NC_013008.1 hypothetical protein 3905085 yggX 8218500 yggX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079752.1 3904810 D 544404 CDS YP_003079753.1 254794916 8218501 3905150..3906229 1 NC_013008.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3906229 mltC 8218501 mltC Escherichia coli O157:H7 str. TW14359 murein transglycosylase C YP_003079753.1 3905150 D 544404 CDS YP_003079754.1 254794917 8218502 3906431..3907687 1 NC_013008.1 nucleoside transporter 3907687 nupG 8218502 nupG Escherichia coli O157:H7 str. TW14359 nucleoside transporter YP_003079754.1 3906431 D 544404 CDS YP_003079755.1 254794918 8218503 complement(3907737..3909872) 1 NC_013008.1 ornithine decarboxylase 3909872 speC 8218503 speC Escherichia coli O157:H7 str. TW14359 ornithine decarboxylase YP_003079755.1 3907737 R 544404 CDS YP_003079756.1 254794919 8218504 3910270..3910977 1 NC_013008.1 inner membrane protein 3910977 yqgA 8218504 yqgA Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079756.1 3910270 D 544404 CDS YP_003079757.1 254794920 8218506 3911356..3912621 1 NC_013008.1 pathogenicity island integrase 3912621 8218506 ECSP_3940 Escherichia coli O157:H7 str. TW14359 pathogenicity island integrase YP_003079757.1 3911356 D 544404 CDS YP_003079758.1 254794921 8218507 complement(3912738..3913523) 1 NC_013008.1 hypothetical protein 3913523 8218507 ECSP_3941 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079758.1 3912738 R 544404 CDS YP_003079759.1 254794922 8218508 3913612..3914286 1 NC_013008.1 hypothetical protein 3914286 8218508 ECSP_3942 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079759.1 3913612 D 544404 CDS YP_003079760.1 254794923 8218509 3914283..3914630 1 NC_013008.1 hypothetical protein 3914630 8218509 ECSP_3943 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079760.1 3914283 D 544404 CDS YP_003079761.1 254794924 8218510 3914650..3915852 1 NC_013008.1 hypothetical protein 3915852 8218510 ECSP_3944 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079761.1 3914650 D 544404 CDS YP_003079762.1 254794925 8218511 complement(3915899..3916843) 1 NC_013008.1 hypothetical protein 3916843 8218511 ECSP_3945 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079762.1 3915899 R 544404 CDS YP_003079763.1 254794926 8218512 complement(3916952..3917500) 1 NC_013008.1 PagC-like membrane protein 3917500 8218512 ECSP_3946 Escherichia coli O157:H7 str. TW14359 PagC-like membrane protein YP_003079763.1 3916952 R 544404 CDS YP_003079764.1 254794927 8218513 complement(3918073..3918273) 1 NC_013008.1 hypothetical protein 3918273 8218513 ECSP_3947 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079764.1 3918073 R 544404 CDS YP_003079765.1 254794928 8218514 complement(3918559..3919113) 1 NC_013008.1 hypothetical protein 3919113 8218514 ECSP_3948 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079765.1 3918559 R 544404 CDS YP_003079766.1 254794929 8218515 3918802..3919692 1 NC_013008.1 transposase 3919692 8218515 ECSP_3949 Escherichia coli O157:H7 str. TW14359 transposase YP_003079766.1 3918802 D 544404 CDS YP_003079767.1 254794930 8218516 3920166..3920336 1 NC_013008.1 hypothetical protein 3920336 8218516 ECSP_3950 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079767.1 3920166 D 544404 CDS YP_003079768.1 254794931 8218517 3920480..3922129 1 NC_013008.1 non-LEE-encoded type III effector 3922129 espL2 8218517 espL2 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003079768.1 3920480 D 544404 CDS YP_003079769.1 254794932 8218518 3922320..3922496 1 NC_013008.1 hypothetical protein 3922496 8218518 ECSP_3952 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079769.1 3922320 D 544404 CDS YP_003079770.1 254794933 8218519 3922737..3923726 1 NC_013008.1 non-LEE-encoded type III effector 3923726 nleB2 8218519 nleB2 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003079770.1 3922737 D 544404 CDS YP_003079771.1 254794934 8218520 3923775..3924449 1 NC_013008.1 non-LEE-encoded type III effector 3924449 nleE 8218520 nleE Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003079771.1 3923775 D 544404 CDS YP_003079772.1 254794935 8218521 3924827..3925672 1 NC_013008.1 transposase 3925672 8218521 ECSP_3955 Escherichia coli O157:H7 str. TW14359 transposase YP_003079772.1 3924827 D 544404 CDS YP_003079773.1 254794936 8218524 complement(3928498..3929388) 1 NC_013008.1 transposase 3929388 8218524 ECSP_3958 Escherichia coli O157:H7 str. TW14359 transposase YP_003079773.1 3928498 R 544404 CDS YP_003079774.1 254794937 8218525 complement(3929385..3929711) 1 NC_013008.1 transposase 3929711 8218525 ECSP_3959 Escherichia coli O157:H7 str. TW14359 transposase YP_003079774.1 3929385 R 544404 CDS YP_003079775.1 254794938 8218526 3929902..3930249 1 NC_013008.1 transposase 3930249 8218526 ECSP_3960 Escherichia coli O157:H7 str. TW14359 transposase YP_003079775.1 3929902 D 544404 CDS YP_003079776.1 254794939 8218527 3930299..3931837 1 NC_013008.1 transposase, ISEc8 3931837 8218527 ECSP_3961 Escherichia coli O157:H7 str. TW14359 transposase, ISEc8 YP_003079776.1 3930299 D 544404 CDS YP_003079777.1 254794940 8218528 3932060..3932410 1 NC_013008.1 hypothetical protein 3932410 8218528 ECSP_3962 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079777.1 3932060 D 544404 CDS YP_003079778.1 254794941 8218529 3932623..3934026 1 NC_013008.1 hypothetical protein 3934026 8218529 ECSP_3963 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079778.1 3932623 D 544404 CDS YP_003079779.1 254794942 8218530 3934118..3934288 1 NC_013008.1 transposase 3934288 8218530 ECSP_3964 Escherichia coli O157:H7 str. TW14359 transposase YP_003079779.1 3934118 D 544404 CDS YP_003079780.1 254794943 8218531 3934345..3934689 1 NC_013008.1 transposase 3934689 8218531 ECSP_3965 Escherichia coli O157:H7 str. TW14359 transposase YP_003079780.1 3934345 D 544404 CDS YP_003079781.1 254794944 8218532 complement(3934532..3935848) 1 NC_013008.1 phosphate/sulfate permease 3935848 8218532 ECSP_3966 Escherichia coli O157:H7 str. TW14359 phosphate/sulfate permease YP_003079781.1 3934532 R 544404 CDS YP_003079782.1 254794945 8218533 complement(3936140..3937999) 1 NC_013008.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3937999 gsp 8218533 gsp Escherichia coli O157:H7 str. TW14359 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_003079782.1 3936140 R 544404 CDS YP_003079783.1 254794946 8218534 3938204..3939070 1 NC_013008.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 3939070 yghU 8218534 yghU Escherichia coli O157:H7 str. TW14359 glutathione S-transferase YghU YP_003079783.1 3938204 D 544404 CDS YP_003079784.1 254794947 8218535 complement(3939193..3939441) 1 NC_013008.1 hydrogenase 2 accessory protein HypG 3939441 hybG 8218535 hybG Escherichia coli O157:H7 str. TW14359 hydrogenase 2 accessory protein HypG YP_003079784.1 3939193 R 544404 CDS YP_003079785.1 254794948 8218536 complement(3939454..3939795) 1 NC_013008.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3939795 hybF 8218536 hybF Escherichia coli O157:H7 str. TW14359 hydrogenase nickel incorporation protein HybF YP_003079785.1 3939454 R 544404 CDS YP_003079786.1 254794949 8218537 complement(3939788..3940276) 1 NC_013008.1 hydrogenase 2-specific chaperone 3940276 hybE 8218537 hybE Escherichia coli O157:H7 str. TW14359 hydrogenase 2-specific chaperone YP_003079786.1 3939788 R 544404 CDS YP_003079787.1 254794950 8218538 complement(3940269..3940763) 1 NC_013008.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3940763 hybD 8218538 hybD Escherichia coli O157:H7 str. TW14359 hydrogenase 2 maturation endopeptidase YP_003079787.1 3940269 R 544404 CDS YP_003079788.1 254794951 8218539 complement(3940763..3942466) 1 NC_013008.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3942466 hybC 8218539 hybC Escherichia coli O157:H7 str. TW14359 hydrogenase 2 large subunit YP_003079788.1 3940763 R 544404 CDS YP_003079789.1 254794952 8218540 complement(3942463..3943641) 1 NC_013008.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3943641 hybB 8218540 hybB Escherichia coli O157:H7 str. TW14359 hydrogenase 2 b cytochrome subunit YP_003079789.1 3942463 R 544404 CDS YP_003079790.1 254794953 8218541 complement(3943631..3944617) 1 NC_013008.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3944617 hybA 8218541 hybA Escherichia coli O157:H7 str. TW14359 hydrogenase 2 protein HybA YP_003079790.1 3943631 R 544404 CDS YP_003079791.1 254794954 8218542 complement(3944620..3945738) 1 NC_013008.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3945738 hybO 8218542 hybO Escherichia coli O157:H7 str. TW14359 hydrogenase 2 small subunit YP_003079791.1 3944620 R 544404 CDS YP_003079792.1 254794955 8218543 complement(3945927..3946214) 1 NC_013008.1 hypothetical protein 3946214 yghW 8218543 yghW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079792.1 3945927 R 544404 CDS YP_003079793.1 254794956 8218544 complement(3946333..3947220) 1 NC_013008.1 hydrolase 3947220 yghX 8218544 yghX Escherichia coli O157:H7 str. TW14359 hydrolase YP_003079793.1 3946333 R 544404 CDS YP_003079794.1 254794957 8218545 3947377..3948417 1 NC_013008.1 aldo/keto reductase 3948417 yghZ 8218545 yghZ Escherichia coli O157:H7 str. TW14359 aldo/keto reductase YP_003079794.1 3947377 D 544404 CDS YP_003079795.1 254794958 8218546 complement(3948457..3948951) 1 NC_013008.1 hypothetical protein 3948951 yqhA 8218546 yqhA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079795.1 3948457 R 544404 CDS YP_003079796.1 254794959 8218547 3949142..3950026 1 NC_013008.1 oxidoreductase 3950026 yghA 8218547 yghA Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003079796.1 3949142 D 544404 CDS YP_003079797.1 254794960 8218548 complement(3950298..3950723) 1 NC_013008.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3950723 exbD 8218548 exbD Escherichia coli O157:H7 str. TW14359 biopolymer transport protein ExbD YP_003079797.1 3950298 R 544404 CDS YP_003079798.1 254794961 8218549 complement(3950730..3951464) 1 NC_013008.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3951464 exbB 8218549 exbB Escherichia coli O157:H7 str. TW14359 biopolymer transport protein ExbB YP_003079798.1 3950730 R 544404 CDS YP_003079799.1 254794962 8218550 3951716..3952903 1 NC_013008.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3952903 metC 8218550 metC Escherichia coli O157:H7 str. TW14359 cystathionine beta-lyase YP_003079799.1 3951716 D 544404 CDS YP_003079800.1 254794963 8218551 3953043..3953702 1 NC_013008.1 hypothetical protein 3953702 yghB 8218551 yghB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079800.1 3953043 D 544404 CDS YP_003079801.1 254794964 8218552 complement(3953742..3954698) 1 NC_013008.1 DNA-binding transcriptional regulator 3954698 yqhC 8218552 yqhC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079801.1 3953742 R 544404 CDS YP_003079802.1 254794965 8218553 3954835..3955998 1 NC_013008.1 NADP-dependent alcohol dehydrogenase 3955998 yqhD 8218553 yqhD Escherichia coli O157:H7 str. TW14359 NADP-dependent alcohol dehydrogenase YP_003079802.1 3954835 D 544404 CDS YP_003079803.1 254794966 8218554 3956103..3956930 1 NC_013008.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3956930 dkgA 8218554 dkgA Escherichia coli O157:H7 str. TW14359 2,5-diketo-D-gluconate reductase A YP_003079803.1 3956103 D 544404 CDS YP_003079804.1 254794967 8218555 3957130..3957405 1 NC_013008.1 hypothetical protein 3957405 8218555 ECSP_3989 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079804.1 3957130 D 544404 CDS YP_003079805.1 254794968 8218556 3957399..3958052 1 NC_013008.1 hypothetical protein 3958052 yqhG 8218556 yqhG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079805.1 3957399 D 544404 CDS YP_003079806.1 254794969 8218557 3958101..3958358 1 NC_013008.1 outer membrane lipoprotein 3958358 yqhH 8218557 yqhH Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003079806.1 3958101 D 544404 CDS YP_003079807.1 254794970 8218558 complement(3958401..3960620) 1 NC_013008.1 hypothetical protein 3960620 ygiQ 8218558 ygiQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079807.1 3958401 R 544404 CDS YP_003079808.1 254794971 8218559 complement(3960731..3962143) 1 NC_013008.1 repressor protein for FtsI 3962143 sufI 8218559 sufI Escherichia coli O157:H7 str. TW14359 repressor protein for FtsI YP_003079808.1 3960731 R 544404 CDS YP_003079809.1 254794972 8218560 complement(3962218..3962955) 1 NC_013008.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 3962955 plsC 8218560 plsC Escherichia coli O157:H7 str. TW14359 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_003079809.1 3962218 R 544404 CDS YP_003079810.1 254794973 8218561 complement(3963189..3965447) 1 NC_013008.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3965447 parC 8218561 parC Escherichia coli O157:H7 str. TW14359 DNA topoisomerase IV subunit A YP_003079810.1 3963189 R 544404 CDS YP_003079811.1 254794974 8218562 complement(3965585..3967192) 1 NC_013008.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; binding protein 3967192 ygiS 8218562 ygiS Escherichia coli O157:H7 str. TW14359 binding protein YP_003079811.1 3965585 R 544404 CDS YP_003079812.1 254794975 8218563 complement(3967301..3967783) 1 NC_013008.1 transcriptional regulator 3967783 ygiV 8218563 ygiV Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003079812.1 3967301 R 544404 CDS YP_003079813.1 254794976 8218564 complement(3967836..3968228) 1 NC_013008.1 hypothetical protein 3968228 ygiW 8218564 ygiW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079813.1 3967836 R 544404 CDS YP_003079814.1 254794977 8218565 3968380..3969039 1 NC_013008.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3969039 qseB 8218565 qseB Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator QseB YP_003079814.1 3968380 D 544404 CDS YP_003079815.1 254794978 8218566 3969036..3970385 1 NC_013008.1 sensor protein QseC 3970385 qseC 8218566 qseC Escherichia coli O157:H7 str. TW14359 sensor protein QseC YP_003079815.1 3969036 D 544404 CDS YP_003079816.1 254794979 8218567 3970495..3971076 1 NC_013008.1 NADPH quinone reductase 3971076 mdaB 8218567 mdaB Escherichia coli O157:H7 str. TW14359 NADPH quinone reductase YP_003079816.1 3970495 D 544404 CDS YP_003079817.1 254794980 8218568 3971107..3971421 1 NC_013008.1 quinol monooxygenase 3971421 ygiN 8218568 ygiN Escherichia coli O157:H7 str. TW14359 quinol monooxygenase YP_003079817.1 3971107 D 544404 CDS YP_003079818.1 254794981 8218569 complement(3971466..3972353) 1 NC_013008.1 hypothetical protein 3972353 8218569 ECSP_4003 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079818.1 3971466 R 544404 CDS YP_003079819.1 254794982 8218570 complement(3972350..3973297) 1 NC_013008.1 iron compound-binding protein of ABC transporter family 3973297 8218570 ECSP_4004 Escherichia coli O157:H7 str. TW14359 iron compound-binding protein of ABC transporter family YP_003079819.1 3972350 R 544404 CDS YP_003079820.1 254794983 8218571 complement(3973308..3974357) 1 NC_013008.1 iron compound permease of ABC transporter family 3974357 8218571 ECSP_4005 Escherichia coli O157:H7 str. TW14359 iron compound permease of ABC transporter family YP_003079820.1 3973308 R 544404 CDS YP_003079821.1 254794984 8218572 complement(3974354..3975337) 1 NC_013008.1 iron compound permease of ABC transporter family 3975337 8218572 ECSP_4006 Escherichia coli O157:H7 str. TW14359 iron compound permease of ABC transporter family YP_003079821.1 3974354 R 544404 CDS YP_003079822.1 254794985 8218573 complement(3975334..3976143) 1 NC_013008.1 ATP-binding protein of ABC transporter family 3976143 8218573 ECSP_4007 Escherichia coli O157:H7 str. TW14359 ATP-binding protein of ABC transporter family YP_003079822.1 3975334 R 544404 CDS YP_003079823.1 254794986 8218574 3976517..3978658 1 NC_013008.1 iron compound receptor 3978658 8218574 ECSP_4008 Escherichia coli O157:H7 str. TW14359 iron compound receptor YP_003079823.1 3976517 D 544404 CDS YP_003079824.1 254794987 8218575 complement(3978722..3980614) 1 NC_013008.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3980614 parE 8218575 parE Escherichia coli O157:H7 str. TW14359 DNA topoisomerase IV subunit B YP_003079824.1 3978722 R 544404 CDS YP_003079825.1 254794988 8218576 complement(3980643..3981224) 1 NC_013008.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 3981224 yqiA 8218576 yqiA Escherichia coli O157:H7 str. TW14359 esterase YqiA YP_003079825.1 3980643 R 544404 CDS YP_003079826.1 254794989 8218577 complement(3981224..3982051) 1 NC_013008.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 3982051 cpdA 8218577 cpdA Escherichia coli O157:H7 str. TW14359 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_003079826.1 3981224 R 544404 CDS YP_003079827.1 254794990 8218578 complement(3982076..3982498) 1 NC_013008.1 hypothetical protein 3982498 yqiB 8218578 yqiB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079827.1 3982076 R 544404 CDS YP_003079828.1 254794991 8218579 complement(3982499..3983128) 1 NC_013008.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase 3983128 nudF 8218579 nudF Escherichia coli O157:H7 str. TW14359 ADP-ribose pyrophosphatase YP_003079828.1 3982499 R 544404 CDS YP_003079829.1 254794992 8218580 3983333..3984814 1 NC_013008.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3984814 tolC 8218580 tolC Escherichia coli O157:H7 str. TW14359 outer membrane channel protein YP_003079829.1 3983333 D 544404 CDS YP_003079830.1 254794993 8218581 3984962..3985633 1 NC_013008.1 hypothetical protein 3985633 ygiB 8218581 ygiB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079830.1 3984962 D 544404 CDS YP_003079831.1 254794994 8218582 3985639..3986799 1 NC_013008.1 hypothetical protein 3986799 ygiC 8218582 ygiC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079831.1 3985639 D 544404 CDS YP_003079832.1 254794995 8218583 complement(3986837..3987625) 1 NC_013008.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3987625 ygiD 8218583 ygiD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079832.1 3986837 R 544404 CDS YP_003079833.1 254794996 8218584 3987768..3988541 1 NC_013008.1 zinc transporter ZupT 3988541 zupT 8218584 zupT Escherichia coli O157:H7 str. TW14359 zinc transporter ZupT YP_003079833.1 3987768 D 544404 CDS YP_003079834.1 254794997 8218585 complement(3988599..3988769) 1 NC_013008.1 hypothetical protein 3988769 8218585 ECSP_4019 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079834.1 3988599 R 544404 CDS YP_003079835.1 254794998 8218586 complement(3989031..3989684) 1 NC_013008.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3989684 ribB 8218586 ribB Escherichia coli O157:H7 str. TW14359 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_003079835.1 3989031 R 544404 CDS YP_003079836.1 254794999 8218587 3990058..3990357 1 NC_013008.1 hypothetical protein 3990357 yqiC 8218587 yqiC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079836.1 3990058 D 544404 CDS YP_003079837.1 254795000 8218588 complement(3990392..3990592) 1 NC_013008.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3990592 glgS 8218588 glgS Escherichia coli O157:H7 str. TW14359 glycogen synthesis protein GlgS YP_003079837.1 3990392 R 544404 CDS YP_003079838.1 254795001 8218589 3990861..3991475 1 NC_013008.1 inner membrane protein 3991475 yqiJ 8218589 yqiJ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079838.1 3990861 D 544404 CDS YP_003079839.1 254795002 8218590 3991517..3993178 1 NC_013008.1 hypothetical protein 3993178 yqiK 8218590 yqiK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079839.1 3991517 D 544404 CDS YP_003079840.1 254795003 8218591 complement(3993972..3995405) 1 NC_013008.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3995405 rfaE 8218591 rfaE Escherichia coli O157:H7 str. TW14359 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_003079840.1 3993972 R 544404 CDS YP_003079841.1 254795004 8218592 complement(3995453..3998293) 1 NC_013008.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3998293 glnE 8218592 glnE Escherichia coli O157:H7 str. TW14359 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_003079841.1 3995453 R 544404 CDS YP_003079842.1 254795005 8218593 complement(3998316..3999617) 1 NC_013008.1 adenylate cyclase 3999617 ygiF 8218593 ygiF Escherichia coli O157:H7 str. TW14359 adenylate cyclase YP_003079842.1 3998316 R 544404 CDS YP_003079843.1 254795006 8218594 3999859..4000479 1 NC_013008.1 signal transduction protein 4000479 htrG 8218594 htrG Escherichia coli O157:H7 str. TW14359 signal transduction protein YP_003079843.1 3999859 D 544404 CDS YP_003079844.1 254795007 8218595 4000543..4001781 1 NC_013008.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 4001781 cca 8218595 cca Escherichia coli O157:H7 str. TW14359 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_003079844.1 4000543 D 544404 CDS YP_003079845.1 254795008 8218596 complement(4001962..4002783) 1 NC_013008.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 4002783 bacA 8218596 bacA Escherichia coli O157:H7 str. TW14359 UDP pyrophosphate phosphatase YP_003079845.1 4001962 R 544404 CDS YP_003079846.1 254795009 8218597 complement(4002874..4003242) 1 NC_013008.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 4003242 folB 8218597 folB Escherichia coli O157:H7 str. TW14359 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_003079846.1 4002874 R 544404 CDS YP_003079847.1 254795010 8218598 4003348..4003965 1 NC_013008.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 4003965 ygiH 8218598 ygiH Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate acyltransferase PlsY YP_003079847.1 4003348 D 544404 CDS YP_003079848.1 254795011 8218599 complement(4003978..4004910) 1 NC_013008.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 4004910 ygiP 8218599 ygiP Escherichia coli O157:H7 str. TW14359 transcriptional activator TtdR YP_003079848.1 4003978 R 544404 CDS YP_003079849.1 254795012 8218600 4005117..4006028 1 NC_013008.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 4006028 ttdA 8218600 ttdA Escherichia coli O157:H7 str. TW14359 tartrate dehydratase subunit alpha YP_003079849.1 4005117 D 544404 CDS YP_003079850.1 254795013 8218601 4006025..4006630 1 NC_013008.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 4006630 ttdB 8218601 ttdB Escherichia coli O157:H7 str. TW14359 L(+)-tartrate dehydratase subunit beta YP_003079850.1 4006025 D 544404 CDS YP_003079851.1 254795014 8218602 4006679..4008142 1 NC_013008.1 tartrate:succinate antiporter 4008142 ygjE 8218602 ygjE Escherichia coli O157:H7 str. TW14359 tartrate:succinate antiporter YP_003079851.1 4006679 D 544404 CDS YP_003079852.1 254795015 8218603 complement(4008185..4009198) 1 NC_013008.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 4009198 ygjD 8218603 ygjD Escherichia coli O157:H7 str. TW14359 DNA-binding/iron metalloprotein/AP endonuclease YP_003079852.1 4008185 R 544404 CDS YP_003079853.1 254795016 8218604 4009436..4009651 1 NC_013008.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 4009651 rpsU 8218604 rpsU Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S21 YP_003079853.1 4009436 D 544404 CDS YP_003079854.1 254795017 8218605 4009762..4011507 1 NC_013008.1 synthesizes RNA primers at the replication forks; DNA primase 4011507 dnaG 8218605 dnaG Escherichia coli O157:H7 str. TW14359 DNA primase YP_003079854.1 4009762 D 544404 CDS YP_003079855.1 254795018 8218606 4011521..4011643 1 NC_013008.1 hypothetical protein 4011643 8218606 ECSP_4040 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079855.1 4011521 D 544404 CDS YP_003079856.1 254795019 8218607 4011702..4013543 1 NC_013008.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 4013543 rpoD 8218607 rpoD Escherichia coli O157:H7 str. TW14359 RNA polymerase sigma factor RpoD YP_003079856.1 4011702 D 544404 CDS YP_003079857.1 254795020 8218608 complement(4013622..4014128) 1 NC_013008.1 G/U mismatch-specific DNA glycosylase 4014128 mug 8218608 mug Escherichia coli O157:H7 str. TW14359 G/U mismatch-specific DNA glycosylase YP_003079857.1 4013622 R 544404 CDS YP_003079858.1 254795021 8218610 complement(4014382..4015146) 1 NC_013008.1 siderophore interacting protein 4015146 yqjH 8218610 yqjH Escherichia coli O157:H7 str. TW14359 siderophore interacting protein YP_003079858.1 4014382 R 544404 CDS YP_003079859.1 254795022 8218611 4015434..4016057 1 NC_013008.1 transcriptional regulator 4016057 yqjI 8218611 yqjI Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003079859.1 4015434 D 544404 CDS YP_003079860.1 254795023 8218612 complement(4016211..4017731) 1 NC_013008.1 fused signal transducer for aerotaxis sensory component, methyl accepting chemotaxis component 4017731 aer 8218612 aer Escherichia coli O157:H7 str. TW14359 fused signal transducer for aerotaxis sensory component, methyl accepting chemotaxis component YP_003079860.1 4016211 R 544404 CDS YP_003079861.1 254795024 8218613 4018149..4019528 1 NC_013008.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 4019528 ygjG 8218613 ygjG Escherichia coli O157:H7 str. TW14359 putrescine--2-oxoglutarate aminotransferase YP_003079861.1 4018149 D 544404 CDS YP_003079862.1 254795025 8218614 complement(4019570..4019902) 1 NC_013008.1 hypothetical protein 4019902 ygjH 8218614 ygjH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079862.1 4019570 R 544404 CDS YP_003079863.1 254795026 8218615 4020121..4021104 1 NC_013008.1 DNA-binding transcriptional repressor EbgR 4021104 ebgR 8218615 ebgR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor EbgR YP_003079863.1 4020121 D 544404 CDS YP_003079864.1 254795027 8218616 4021288..4024380 1 NC_013008.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 4024380 ebgA 8218616 ebgA Escherichia coli O157:H7 str. TW14359 cryptic beta-D-galactosidase subunit alpha YP_003079864.1 4021288 D 544404 CDS YP_003079865.1 254795028 8218617 4024377..4024826 1 NC_013008.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 4024826 ebgC 8218617 ebgC Escherichia coli O157:H7 str. TW14359 cryptic beta-D-galactosidase subunit beta YP_003079865.1 4024377 D 544404 CDS YP_003079866.1 254795029 8218618 4024889..4026322 1 NC_013008.1 transporter 4026322 ygjI 8218618 ygjI Escherichia coli O157:H7 str. TW14359 transporter YP_003079866.1 4024889 D 544404 CDS YP_003079867.1 254795030 8218619 4026456..4027526 1 NC_013008.1 hypothetical protein 4027526 ygjJ 8218619 ygjJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079867.1 4026456 D 544404 CDS YP_003079868.1 254795031 8218620 4027543..4029894 1 NC_013008.1 glycosyl hydrolase 4029894 ygjK 8218620 ygjK Escherichia coli O157:H7 str. TW14359 glycosyl hydrolase YP_003079868.1 4027543 D 544404 CDS YP_003079869.1 254795032 8218621 4030420..4032438 1 NC_013008.1 2,4-dienoyl-CoA reductase 4032438 fadH 8218621 fadH Escherichia coli O157:H7 str. TW14359 2,4-dienoyl-CoA reductase YP_003079869.1 4030420 D 544404 CDS YP_003079870.1 254795033 8218622 complement(4032483..4032899) 1 NC_013008.1 DNA-binding transcriptional regulator 4032899 ygjM 8218622 ygjM Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079870.1 4032483 R 544404 CDS YP_003079871.1 254795034 8218623 complement(4032896..4033210) 1 NC_013008.1 hypothetical protein 4033210 ygjN 8218623 ygjN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079871.1 4032896 R 544404 CDS YP_003079872.1 254795035 8218624 complement(4033494..4034630) 1 NC_013008.1 methyltransferase small domain-containing protein 4034630 ygjO 8218624 ygjO Escherichia coli O157:H7 str. TW14359 methyltransferase small domain-containing protein YP_003079872.1 4033494 R 544404 CDS YP_003079873.1 254795036 8218625 4034715..4035218 1 NC_013008.1 metal dependent hydrolase 4035218 ygjP 8218625 ygjP Escherichia coli O157:H7 str. TW14359 metal dependent hydrolase YP_003079873.1 4034715 D 544404 CDS YP_003079874.1 254795037 8218626 4035295..4035987 1 NC_013008.1 thioredoxin-like protein 4035987 ygjQ 8218626 ygjQ Escherichia coli O157:H7 str. TW14359 thioredoxin-like protein YP_003079874.1 4035295 D 544404 CDS YP_003079875.1 254795038 8218627 4036066..4037052 1 NC_013008.1 NAD(P)-binding dehydrogenase 4037052 ygjR 8218627 ygjR Escherichia coli O157:H7 str. TW14359 NAD(P)-binding dehydrogenase YP_003079875.1 4036066 D 544404 CDS YP_003079876.1 254795039 8218628 4037336..4038301 1 NC_013008.1 inner membrane protein, part of terminus 4038301 alx 8218628 alx Escherichia coli O157:H7 str. TW14359 inner membrane protein, part of terminus YP_003079876.1 4037336 D 544404 CDS YP_003079877.1 254795040 8218629 4038700..4039944 1 NC_013008.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 4039944 sstT 8218629 sstT Escherichia coli O157:H7 str. TW14359 serine/threonine transporter SstT YP_003079877.1 4038700 D 544404 CDS YP_003079878.1 254795041 8218630 complement(4039949..4040500) 1 NC_013008.1 hypothetical protein 4040500 ygjV 8218630 ygjV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079878.1 4039949 R 544404 CDS YP_003079879.1 254795042 8218631 complement(4040583..4042070) 1 NC_013008.1 altronate hydrolase 4042070 uxaA 8218631 uxaA Escherichia coli O157:H7 str. TW14359 altronate hydrolase YP_003079879.1 4040583 R 544404 CDS YP_003079880.1 254795043 8218632 complement(4042085..4043497) 1 NC_013008.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 4043497 uxaC 8218632 uxaC Escherichia coli O157:H7 str. TW14359 glucuronate isomerase YP_003079880.1 4042085 R 544404 CDS YP_003079881.1 254795044 8218633 4043860..4045278 1 NC_013008.1 hexuronate transporter 4045278 exuT 8218633 exuT Escherichia coli O157:H7 str. TW14359 hexuronate transporter YP_003079881.1 4043860 D 544404 CDS YP_003079882.1 254795045 8218634 4045408..4046184 1 NC_013008.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 4046184 exuR 8218634 exuR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor ExuR YP_003079882.1 4045408 D 544404 CDS YP_003079883.1 254795046 8218635 4046529..4047191 1 NC_013008.1 hypothetical protein 4047191 yqjA 8218635 yqjA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079883.1 4046529 D 544404 CDS YP_003079884.1 254795047 8218636 4047195..4047578 1 NC_013008.1 hypothetical protein 4047578 yqjB 8218636 yqjB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079884.1 4047195 D 544404 CDS YP_003079885.1 254795048 8218637 4047725..4048093 1 NC_013008.1 hypothetical protein 4048093 yqjC 8218637 yqjC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079885.1 4047725 D 544404 CDS YP_003079886.1 254795049 8218638 4048131..4048436 1 NC_013008.1 hypothetical protein 4048436 yqjD 8218638 yqjD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079886.1 4048131 D 544404 CDS YP_003079887.1 254795050 8218639 4048439..4048843 1 NC_013008.1 hypothetical protein 4048843 yqjE 8218639 yqjE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079887.1 4048439 D 544404 CDS YP_003079888.1 254795051 8218640 4048833..4049132 1 NC_013008.1 hypothetical protein 4049132 yqjK 8218640 yqjK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079888.1 4048833 D 544404 CDS YP_003079889.1 254795052 8218641 4049318..4049710 1 NC_013008.1 quinol oxidase subunit 4049710 yqjF 8218641 yqjF Escherichia coli O157:H7 str. TW14359 quinol oxidase subunit YP_003079889.1 4049318 D 544404 CDS YP_003079890.1 254795053 8218642 4049780..4050766 1 NC_013008.1 S-transferase 4050766 yqjG 8218642 yqjG Escherichia coli O157:H7 str. TW14359 S-transferase YP_003079890.1 4049780 D 544404 CDS YP_003079891.1 254795054 8218643 4051058..4051423 1 NC_013008.1 inner membrane protein 4051423 yhaH 8218643 yhaH Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079891.1 4051058 D 544404 CDS YP_003079892.1 254795055 8218644 4051664..4052020 1 NC_013008.1 inner membrane protein 4052020 yhaI 8218644 yhaI Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003079892.1 4051664 D 544404 CDS YP_003079893.1 254795056 8218645 complement(4052071..4052967) 1 NC_013008.1 DNA-binding transcriptional regulator 4052967 yhaJ 8218645 yhaJ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079893.1 4052071 R 544404 CDS YP_003079894.1 254795057 8218646 4053072..4053773 1 NC_013008.1 pirin-related protein 4053773 yhaK 8218646 yhaK Escherichia coli O157:H7 str. TW14359 pirin-related protein YP_003079894.1 4053072 D 544404 CDS YP_003079895.1 254795058 8218647 4053796..4053960 1 NC_013008.1 hypothetical protein 4053960 yhaL 8218647 yhaL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079895.1 4053796 D 544404 CDS YP_003079896.1 254795059 8218648 complement(4054094..4055404) 1 NC_013008.1 hypothetical protein 4055404 yhaM 8218648 yhaM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079896.1 4054094 R 544404 CDS YP_003079897.1 254795060 8218649 complement(4055432..4056763) 1 NC_013008.1 transporter 4056763 yhaO 8218649 yhaO Escherichia coli O157:H7 str. TW14359 transporter YP_003079897.1 4055432 R 544404 CDS YP_003079898.1 254795061 8218650 complement(4057038..4058402) 1 NC_013008.1 L-serine dehydratase 3 4058402 tdcG 8218650 tdcG Escherichia coli O157:H7 str. TW14359 L-serine dehydratase 3 YP_003079898.1 4057038 R 544404 CDS YP_003079899.1 254795062 8218651 complement(4058474..4058863) 1 NC_013008.1 hypothetical protein 4058863 tdcF 8218651 tdcF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079899.1 4058474 R 544404 CDS YP_003079900.1 254795063 8218652 complement(4058877..4061171) 1 NC_013008.1 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase 4061171 tdcE 8218652 tdcE Escherichia coli O157:H7 str. TW14359 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase YP_003079900.1 4058877 R 544404 CDS YP_003079901.1 254795064 8218653 complement(4061205..4062413) 1 NC_013008.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 4062413 tdcD 8218653 tdcD Escherichia coli O157:H7 str. TW14359 propionate/acetate kinase YP_003079901.1 4061205 R 544404 CDS YP_003079902.1 254795065 8218654 complement(4062439..4063770) 1 NC_013008.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 4063770 tdcC 8218654 tdcC Escherichia coli O157:H7 str. TW14359 threonine/serine transporter TdcC YP_003079902.1 4062439 R 544404 CDS YP_003079903.1 254795066 8218655 complement(4063792..4064781) 1 NC_013008.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 4064781 tdcB 8218655 tdcB Escherichia coli O157:H7 str. TW14359 threonine dehydratase YP_003079903.1 4063792 R 544404 CDS YP_003079904.1 254795067 8218656 complement(4064880..4065818) 1 NC_013008.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 4065818 tdcA 8218656 tdcA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator TdcA YP_003079904.1 4064880 R 544404 CDS YP_003079905.1 254795068 8218657 4066133..4066351 1 NC_013008.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 4066351 tdcR 8218657 tdcR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator TdcR YP_003079905.1 4066133 D 544404 CDS YP_003079906.1 254795069 8218658 4066607..4067146 1 NC_013008.1 hypothetical protein 4067146 yhaB 8218658 yhaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079906.1 4066607 D 544404 CDS YP_003079907.1 254795070 8218659 4067168..4068355 1 NC_013008.1 hypothetical protein 4068355 yhaC 8218659 yhaC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079907.1 4067168 D 544404 CDS YP_003079908.1 254795071 8218660 4068416..4068571 1 NC_013008.1 hypothetical protein 4068571 8218660 ECSP_4094 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079908.1 4068416 D 544404 CDS YP_003079909.1 254795072 8218661 complement(4068984..4070129) 1 NC_013008.1 glycerate kinase I 4070129 garK 8218661 garK Escherichia coli O157:H7 str. TW14359 glycerate kinase I YP_003079909.1 4068984 R 544404 CDS YP_003079910.1 254795073 8218662 complement(4070226..4071110) 1 NC_013008.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 4071110 garR 8218662 garR Escherichia coli O157:H7 str. TW14359 tartronate semialdehyde reductase YP_003079910.1 4070226 R 544404 CDS YP_003079911.1 254795074 8218663 complement(4071146..4071916) 1 NC_013008.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 4071916 garL 8218663 garL Escherichia coli O157:H7 str. TW14359 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_003079911.1 4071146 R 544404 CDS YP_003079912.1 254795075 8218664 complement(4071932..4073266) 1 NC_013008.1 (D)-galactarate transporter 4073266 garP 8218664 garP Escherichia coli O157:H7 str. TW14359 (D)-galactarate transporter YP_003079912.1 4071932 R 544404 CDS YP_003079913.1 254795076 8218665 4073641..4075212 1 NC_013008.1 (D)-galactarate dehydrogenase 4075212 garD 8218665 garD Escherichia coli O157:H7 str. TW14359 (D)-galactarate dehydrogenase YP_003079913.1 4073641 D 544404 CDS YP_003079914.1 254795077 8218666 4075361..4075696 1 NC_013008.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 4075696 sohA 8218666 sohA Escherichia coli O157:H7 str. TW14359 regulator PrlF YP_003079914.1 4075361 D 544404 CDS YP_003079915.1 254795078 8218667 4075696..4076160 1 NC_013008.1 hypothetical protein 4076160 yhaV 8218667 yhaV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079915.1 4075696 D 544404 CDS YP_003079916.1 254795079 8218668 complement(4076215..4077024) 1 NC_013008.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 4077024 agaR 8218668 agaR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator AgaR YP_003079916.1 4076215 R 544404 CDS YP_003079917.1 254795080 8218669 4077273..4078553 1 NC_013008.1 tagatose-biphosphate aldolase 1, kbaZ subunit 4078553 kbaZ 8218669 kbaZ Escherichia coli O157:H7 str. TW14359 tagatose-biphosphate aldolase 1, kbaZ subunit YP_003079917.1 4077273 D 544404 CDS YP_003079918.1 254795081 8218670 4078576..4079049 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4079049 agaV 8218670 agaV Escherichia coli O157:H7 str. TW14359 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_003079918.1 4078576 D 544404 CDS YP_003079919.1 254795082 8218671 4079060..4079839 1 NC_013008.1 phosphotransferase system enzyme subunit 4079839 agaW 8218671 agaW Escherichia coli O157:H7 str. TW14359 phosphotransferase system enzyme subunit YP_003079919.1 4079060 D 544404 CDS YP_003079920.1 254795083 8218672 4079829..4080707 1 NC_013008.1 phosphotransferase system enzyme subunit 4080707 agaE 8218672 agaE Escherichia coli O157:H7 str. TW14359 phosphotransferase system enzyme subunit YP_003079920.1 4079829 D 544404 CDS YP_003079921.1 254795084 8218673 4080725..4081159 1 NC_013008.1 phosphotransferase system enzyme subunit 4081159 agaF 8218673 agaF Escherichia coli O157:H7 str. TW14359 phosphotransferase system enzyme subunit YP_003079921.1 4080725 D 544404 CDS YP_003079922.1 254795085 8218674 4081156..4082289 1 NC_013008.1 N-acetylgalactosamine-6-phosphate deacetylase 4082289 agaA 8218674 agaA Escherichia coli O157:H7 str. TW14359 N-acetylgalactosamine-6-phosphate deacetylase YP_003079922.1 4081156 D 544404 CDS YP_003079923.1 254795086 8218675 4082407..4082541 1 NC_013008.1 hypothetical protein 4082541 8218675 ECSP_4109 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079923.1 4082407 D 544404 CDS YP_003079924.1 254795087 8218676 4082640..4083794 1 NC_013008.1 tagatose-6-phosphate ketose/aldose isomerase 4083794 agaS 8218676 agaS Escherichia coli O157:H7 str. TW14359 tagatose-6-phosphate ketose/aldose isomerase YP_003079924.1 4082640 D 544404 CDS YP_003079925.1 254795088 8218677 4083807..4084667 1 NC_013008.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 4084667 kbaY 8218677 kbaY Escherichia coli O157:H7 str. TW14359 tagatose-bisphosphate aldolase YP_003079925.1 4083807 D 544404 CDS YP_003079926.1 254795089 8218678 4084834..4085310 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4085310 agaB 8218678 agaB Escherichia coli O157:H7 str. TW14359 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_003079926.1 4084834 D 544404 CDS YP_003079927.1 254795090 8218679 4085577..4086152 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 4086152 agaC 8218679 agaC Escherichia coli O157:H7 str. TW14359 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_003079927.1 4085577 D 544404 CDS YP_003079928.1 254795091 8218680 4086142..4086933 1 NC_013008.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 4086933 agaD 8218680 agaD Escherichia coli O157:H7 str. TW14359 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_003079928.1 4086142 D 544404 CDS YP_003079929.1 254795092 8218682 4088090..4088674 1 NC_013008.1 fimbrial-like adhesin protein 4088674 yraH 8218682 yraH Escherichia coli O157:H7 str. TW14359 fimbrial-like adhesin protein YP_003079929.1 4088090 D 544404 CDS YP_003079930.1 254795093 8218683 4088754..4089449 1 NC_013008.1 periplasmic pilin chaperone 4089449 yraI 8218683 yraI Escherichia coli O157:H7 str. TW14359 periplasmic pilin chaperone YP_003079930.1 4088754 D 544404 CDS YP_003079931.1 254795094 8218684 4089478..4091994 1 NC_013008.1 outer membrane protein 4091994 yraJ 8218684 yraJ Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003079931.1 4089478 D 544404 CDS YP_003079932.1 254795095 8218685 4091834..4092412 1 NC_013008.1 hypothetical protein 4092412 8218685 ECSP_4119 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079932.1 4091834 D 544404 CDS YP_003079933.1 254795096 8218686 4092388..4092738 1 NC_013008.1 fimbrial protein 4092738 8218686 ECSP_4120 Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003079933.1 4092388 D 544404 CDS YP_003079934.1 254795097 8218687 complement(4092781..4093641) 1 NC_013008.1 methyltransferase 4093641 yraL 8218687 yraL Escherichia coli O157:H7 str. TW14359 methyltransferase YP_003079934.1 4092781 R 544404 CDS YP_003079935.1 254795098 8218688 4093706..4095742 1 NC_013008.1 lipoprotein 4095742 yraM 8218688 yraM Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003079935.1 4093706 D 544404 CDS YP_003079936.1 254795099 8218689 4095700..4096095 1 NC_013008.1 hypothetical protein 4096095 yraN 8218689 yraN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079936.1 4095700 D 544404 CDS YP_003079937.1 254795100 8218690 4096115..4096705 1 NC_013008.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 4096705 diaA 8218690 diaA Escherichia coli O157:H7 str. TW14359 DnaA initiator-associating protein DiaA YP_003079937.1 4096115 D 544404 CDS YP_003079938.1 254795101 8218691 4096715..4097290 1 NC_013008.1 hypothetical protein 4097290 yraP 8218691 yraP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079938.1 4096715 D 544404 CDS YP_003079939.1 254795102 8218692 complement(4097404..4098444) 1 NC_013008.1 permease 4098444 yraQ 8218692 yraQ Escherichia coli O157:H7 str. TW14359 permease YP_003079939.1 4097404 R 544404 CDS YP_003079940.1 254795103 8218693 complement(4098517..4099152) 1 NC_013008.1 nucleoside-diphosphate-sugar epimerase 4099152 yraR 8218693 yraR Escherichia coli O157:H7 str. TW14359 nucleoside-diphosphate-sugar epimerase YP_003079940.1 4098517 R 544404 CDS YP_003079941.1 254795104 8218694 4099280..4099798 1 NC_013008.1 intracellular protease 4099798 yhbO 8218694 yhbO Escherichia coli O157:H7 str. TW14359 intracellular protease YP_003079941.1 4099280 D 544404 CDS YP_003079942.1 254795105 8218695 complement(4099778..4100221) 1 NC_013008.1 hypothetical protein 4100221 yhbP 8218695 yhbP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079942.1 4099778 R 544404 CDS YP_003079943.1 254795106 8218696 4100272..4100574 1 NC_013008.1 GIY-YIG nuclease superfamily protein 4100574 yhbQ 8218696 yhbQ Escherichia coli O157:H7 str. TW14359 GIY-YIG nuclease superfamily protein YP_003079943.1 4100272 D 544404 CDS YP_003079944.1 254795107 8218697 complement(4100561..4101064) 1 NC_013008.1 acyl-CoA N-acyltransferase domain-containing acyltransferase 4101064 yhbS 8218697 yhbS Escherichia coli O157:H7 str. TW14359 acyl-CoA N-acyltransferase domain-containing acyltransferase YP_003079944.1 4100561 R 544404 CDS YP_003079945.1 254795108 8218698 complement(4101058..4101582) 1 NC_013008.1 lipid carrier protein 4101582 yhbT 8218698 yhbT Escherichia coli O157:H7 str. TW14359 lipid carrier protein YP_003079945.1 4101058 R 544404 CDS YP_003079946.1 254795109 8218699 4101791..4102786 1 NC_013008.1 collagenase-like peptidase 4102786 yhbU 8218699 yhbU Escherichia coli O157:H7 str. TW14359 collagenase-like peptidase YP_003079946.1 4101791 D 544404 CDS YP_003079947.1 254795110 8218700 4102795..4103673 1 NC_013008.1 protease 4103673 yhbV 8218700 yhbV Escherichia coli O157:H7 str. TW14359 protease YP_003079947.1 4102795 D 544404 CDS YP_003079948.1 254795111 8218701 4103754..4104761 1 NC_013008.1 hypothetical protein 4104761 yhbW 8218701 yhbW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079948.1 4103754 D 544404 CDS YP_003079949.1 254795112 8218702 complement(4104878..4106122) 1 NC_013008.1 tryptophan transporter of high affinity; tryptophan permease 4106122 mtr 8218702 mtr Escherichia coli O157:H7 str. TW14359 tryptophan permease YP_003079949.1 4104878 R 544404 CDS YP_003079950.1 254795113 8218703 complement(4106276..4108165) 1 NC_013008.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 4108165 deaD 8218703 deaD Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase DeaD YP_003079950.1 4106276 R 544404 CDS YP_003079951.1 254795114 8218704 complement(4108345..4109229) 1 NC_013008.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 4109229 nlpI 8218704 nlpI Escherichia coli O157:H7 str. TW14359 lipoprotein NlpI YP_003079951.1 4108345 R 544404 CDS YP_003079952.1 254795115 8218705 complement(4109338..4111473) 1 NC_013008.1 polynucleotide phosphorylase 4111473 pnp 8218705 pnp Escherichia coli O157:H7 str. TW14359 polynucleotide phosphorylase YP_003079952.1 4109338 R 544404 CDS YP_003079953.1 254795116 8218706 complement(4111720..4111989) 1 NC_013008.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 4111989 rpsO 8218706 rpsO Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S15 YP_003079953.1 4111720 R 544404 CDS YP_003079954.1 254795117 8218707 complement(4112138..4113082) 1 NC_013008.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 4113082 truB 8218707 truB Escherichia coli O157:H7 str. TW14359 tRNA pseudouridine synthase B YP_003079954.1 4112138 R 544404 CDS YP_003079955.1 254795118 8218708 complement(4113082..4113483) 1 NC_013008.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 4113483 rbfA 8218708 rbfA Escherichia coli O157:H7 str. TW14359 ribosome-binding factor A YP_003079955.1 4113082 R 544404 CDS YP_003079956.1 254795119 8218709 complement(4113648..4116320) 1 NC_013008.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 4116320 infB 8218709 infB Escherichia coli O157:H7 str. TW14359 translation initiation factor IF-2 YP_003079956.1 4113648 R 544404 CDS YP_003079957.1 254795120 8218710 complement(4116345..4117832) 1 NC_013008.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 4117832 nusA 8218710 nusA Escherichia coli O157:H7 str. TW14359 transcription elongation factor NusA YP_003079957.1 4116345 R 544404 CDS YP_003079958.1 254795121 8218711 complement(4117860..4118312) 1 NC_013008.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 4118312 yhbC 8218711 yhbC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079958.1 4117860 R 544404 CDS YP_003079959.1 254795122 8218713 4118943..4120286 1 NC_013008.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 4120286 argG 8218713 argG Escherichia coli O157:H7 str. TW14359 argininosuccinate synthase YP_003079959.1 4118943 D 544404 CDS YP_003079960.1 254795123 8218714 complement(4120294..4121919) 1 NC_013008.1 hydrolase 4121919 yhbX 8218714 yhbX Escherichia coli O157:H7 str. TW14359 hydrolase YP_003079960.1 4120294 R 544404 CDS YP_003079961.1 254795124 8218716 complement(4122479..4122811) 1 NC_013008.1 preprotein translocase subunit SecG 4122811 secG 8218716 secG Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecG YP_003079961.1 4122479 R 544404 CDS YP_003079962.1 254795125 8218717 complement(4123039..4124376) 1 NC_013008.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 4124376 glmM 8218717 glmM Escherichia coli O157:H7 str. TW14359 phosphoglucosamine mutase YP_003079962.1 4123039 R 544404 CDS YP_003079963.1 254795126 8218718 complement(4124369..4125217) 1 NC_013008.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 4125217 folP 8218718 folP Escherichia coli O157:H7 str. TW14359 dihydropteroate synthase YP_003079963.1 4124369 R 544404 CDS YP_003079964.1 254795127 8218719 complement(4125307..4127241) 1 NC_013008.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 4127241 hflB 8218719 hflB Escherichia coli O157:H7 str. TW14359 ATP-dependent metalloprotease YP_003079964.1 4125307 R 544404 CDS YP_003079965.1 254795128 8218720 complement(4127341..4127970) 1 NC_013008.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 4127970 rrmJ 8218720 rrmJ Escherichia coli O157:H7 str. TW14359 23S rRNA methyltransferase YP_003079965.1 4127341 R 544404 CDS YP_003079966.1 254795129 8218721 4128096..4128389 1 NC_013008.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 4128389 yhbY 8218721 yhbY Escherichia coli O157:H7 str. TW14359 RNA-binding protein YhbY YP_003079966.1 4128096 D 544404 CDS YP_003079967.1 254795130 8218722 complement(4128545..4129021) 1 NC_013008.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 4129021 greA 8218722 greA Escherichia coli O157:H7 str. TW14359 transcription elongation factor GreA YP_003079967.1 4128545 R 544404 CDS YP_003079968.1 254795131 8218723 4129269..4130702 1 NC_013008.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 4130702 dacB 8218723 dacB Escherichia coli O157:H7 str. TW14359 D-alanyl-D-alanine carboxypeptidase/endopeptidase YP_003079968.1 4129269 D 544404 CDS YP_003079969.1 254795132 8218724 complement(4130742..4131914) 1 NC_013008.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 4131914 obgE 8218724 obgE Escherichia coli O157:H7 str. TW14359 GTPase ObgE YP_003079969.1 4130742 R 544404 CDS YP_003079970.1 254795133 8218725 complement(4131930..4132895) 1 NC_013008.1 hypothetical protein 4132895 yhbE 8218725 yhbE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079970.1 4131930 R 544404 CDS YP_003079971.1 254795134 8218726 complement(4133022..4133279) 1 NC_013008.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 4133279 rpmA 8218726 rpmA Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L27 YP_003079971.1 4133022 R 544404 CDS YP_003079972.1 254795135 8218727 complement(4133300..4133611) 1 NC_013008.1 50S ribosomal protein L21 4133611 rplU 8218727 rplU Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L21 YP_003079972.1 4133300 R 544404 CDS YP_003079973.1 254795136 8218728 4133870..4134841 1 NC_013008.1 octaprenyl diphosphate synthase 4134841 ispB 8218728 ispB Escherichia coli O157:H7 str. TW14359 octaprenyl diphosphate synthase YP_003079973.1 4133870 D 544404 CDS YP_003079974.1 254795137 8218729 4135070..4135348 1 NC_013008.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 4135348 sfsB 8218729 sfsB Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator Nlp YP_003079974.1 4135070 D 544404 CDS YP_003079975.1 254795138 8218730 complement(4135396..4136655) 1 NC_013008.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4136655 murA 8218730 murA Escherichia coli O157:H7 str. TW14359 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_003079975.1 4135396 R 544404 CDS YP_003079976.1 254795139 8218731 complement(4136710..4136964) 1 NC_013008.1 DNA-binding transcriptional regulator 4136964 yrbA 8218731 yrbA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003079976.1 4136710 R 544404 CDS YP_003079977.1 254795140 8218732 complement(4137124..4137417) 1 NC_013008.1 hypothetical protein 4137417 yrbB 8218732 yrbB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079977.1 4137124 R 544404 CDS YP_003079978.1 254795141 8218733 complement(4137417..4138052) 1 NC_013008.1 ABC-type organic solvent transporter 4138052 yrbC 8218733 yrbC Escherichia coli O157:H7 str. TW14359 ABC-type organic solvent transporter YP_003079978.1 4137417 R 544404 CDS YP_003079979.1 254795142 8218734 complement(4138071..4138622) 1 NC_013008.1 ABC-type organic solvent transporter 4138622 yrbD 8218734 yrbD Escherichia coli O157:H7 str. TW14359 ABC-type organic solvent transporter YP_003079979.1 4138071 R 544404 CDS YP_003079980.1 254795143 8218735 complement(4138627..4139409) 1 NC_013008.1 toluene ABC transporter membrane protein 4139409 yrbE 8218735 yrbE Escherichia coli O157:H7 str. TW14359 toluene ABC transporter membrane protein YP_003079980.1 4138627 R 544404 CDS YP_003079981.1 254795144 8218736 complement(4139417..4140226) 1 NC_013008.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF 4140226 yrbF 8218736 yrbF Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YrbF YP_003079981.1 4139417 R 544404 CDS YP_003079982.1 254795145 8218737 4140436..4141413 1 NC_013008.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 4141413 yrbG 8218737 yrbG Escherichia coli O157:H7 str. TW14359 calcium/sodium:proton antiporter YP_003079982.1 4140436 D 544404 CDS YP_003079983.1 254795146 8218738 4141427..4142413 1 NC_013008.1 D-arabinose 5-phosphate isomerase 4142413 kdsD 8218738 kdsD Escherichia coli O157:H7 str. TW14359 D-arabinose 5-phosphate isomerase YP_003079983.1 4141427 D 544404 CDS YP_003079984.1 254795147 8218739 4142434..4143000 1 NC_013008.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 4143000 kdsC 8218739 kdsC Escherichia coli O157:H7 str. TW14359 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_003079984.1 4142434 D 544404 CDS YP_003079985.1 254795148 8218740 4142997..4143572 1 NC_013008.1 hypothetical protein 4143572 yrbK 8218740 yrbK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079985.1 4142997 D 544404 CDS YP_003079986.1 254795149 8218741 4143541..4144098 1 NC_013008.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 4144098 yhbN 8218741 yhbN Escherichia coli O157:H7 str. TW14359 lipopolysaccharide transport periplasmic protein LptA YP_003079986.1 4143541 D 544404 CDS YP_003079987.1 254795150 8218742 4144105..4144830 1 NC_013008.1 ABC transporter ATP-binding protein YhbG 4144830 yhbG 8218742 yhbG Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YhbG YP_003079987.1 4144105 D 544404 CDS YP_003079988.1 254795151 8218743 4144878..4146311 1 NC_013008.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 4146311 rpoN 8218743 rpoN Escherichia coli O157:H7 str. TW14359 RNA polymerase factor sigma-54 YP_003079988.1 4144878 D 544404 CDS YP_003079989.1 254795152 8218744 4146334..4146621 1 NC_013008.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 4146621 hpf 8218744 hpf Escherichia coli O157:H7 str. TW14359 sigma(54) modulation protein YP_003079989.1 4146334 D 544404 CDS YP_003079990.1 254795153 8218745 4146739..4147230 1 NC_013008.1 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 4147230 ptsN 8218745 ptsN Escherichia coli O157:H7 str. TW14359 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_003079990.1 4146739 D 544404 CDS YP_003079991.1 254795154 8218746 4147276..4148130 1 NC_013008.1 hypothetical protein 4148130 yhbJ 8218746 yhbJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079991.1 4147276 D 544404 CDS YP_003079992.1 254795155 8218747 4148127..4148399 1 NC_013008.1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 4148399 npr 8218747 npr Escherichia coli O157:H7 str. TW14359 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_003079992.1 4148127 D 544404 CDS YP_003079993.1 254795156 8218748 4148613..4149245 1 NC_013008.1 hypothetical protein 4149245 yrbL 8218748 yrbL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003079993.1 4148613 D 544404 CDS YP_003079994.1 254795157 8218749 complement(4149242..4149970) 1 NC_013008.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 4149970 mtgA 8218749 mtgA Escherichia coli O157:H7 str. TW14359 monofunctional biosynthetic peptidoglycan transglycosylase YP_003079994.1 4149242 R 544404 CDS YP_003079995.1 254795158 8218750 complement(4149967..4150620) 1 NC_013008.1 isoprenoid biosynthesis protein with amidotransferase-like domain 4150620 elbB 8218750 elbB Escherichia coli O157:H7 str. TW14359 isoprenoid biosynthesis protein with amidotransferase-like domain YP_003079995.1 4149967 R 544404 CDS YP_003079996.1 254795159 8218751 complement(4150850..4153186) 1 NC_013008.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 4153186 arcB 8218751 arcB Escherichia coli O157:H7 str. TW14359 aerobic respiration control sensor protein ArcB YP_003079996.1 4150850 R 544404 CDS YP_003079997.1 254795160 8218752 complement(4153282..4154211) 1 NC_013008.1 Fe-S oxidoreductase 4154211 yhcC 8218752 yhcC Escherichia coli O157:H7 str. TW14359 Fe-S oxidoreductase YP_003079997.1 4153282 R 544404 CDS YP_003079998.1 254795161 8218753 4154792..4159345 1 NC_013008.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 4159345 gltB 8218753 gltB Escherichia coli O157:H7 str. TW14359 glutamate synthase subunit alpha YP_003079998.1 4154792 D 544404 CDS YP_003079999.1 254795162 8218754 4159358..4160776 1 NC_013008.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 4160776 gltD 8218754 gltD Escherichia coli O157:H7 str. TW14359 glutamate synthase subunit beta YP_003079999.1 4159358 D 544404 CDS YP_003080000.1 254795163 8218755 4160960..4162009 1 NC_013008.1 hypothetical protein 4162009 yhcG 8218755 yhcG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080000.1 4160960 D 544404 CDS YP_003080001.1 254795164 8218756 complement(4162069..4162533) 1 NC_013008.1 hypothetical protein 4162533 yhcH 8218756 yhcH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080001.1 4162069 R 544404 CDS YP_003080002.1 254795165 8218757 complement(4162530..4163405) 1 NC_013008.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 4163405 nanK 8218757 nanK Escherichia coli O157:H7 str. TW14359 N-acetylmannosamine kinase YP_003080002.1 4162530 R 544404 CDS YP_003080003.1 254795166 8218758 complement(4163402..4164091) 1 NC_013008.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 4164091 nanE 8218758 nanE Escherichia coli O157:H7 str. TW14359 N-acetylmannosamine-6-phosphate 2-epimerase YP_003080003.1 4163402 R 544404 CDS YP_003080004.1 254795167 8218759 complement(4164139..4165629) 1 NC_013008.1 sialic acid transporter 4165629 nanT 8218759 nanT Escherichia coli O157:H7 str. TW14359 sialic acid transporter YP_003080004.1 4164139 R 544404 CDS YP_003080005.1 254795168 8218760 complement(4165738..4166631) 1 NC_013008.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 4166631 nanA 8218760 nanA Escherichia coli O157:H7 str. TW14359 N-acetylneuraminate lyase YP_003080005.1 4165738 R 544404 CDS YP_003080006.1 254795169 8218761 complement(4166753..4167544) 1 NC_013008.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 4167544 nanR 8218761 nanR Escherichia coli O157:H7 str. TW14359 transcriptional regulator NanR YP_003080006.1 4166753 R 544404 CDS YP_003080007.1 254795170 8218762 4167924..4169288 1 NC_013008.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; cryptic C4-dicarboxylate transporter DcuD 4169288 dcuD 8218762 dcuD Escherichia coli O157:H7 str. TW14359 cryptic C4-dicarboxylate transporter DcuD YP_003080007.1 4167924 D 544404 CDS YP_003080008.1 254795171 8218763 complement(4169323..4169820) 1 NC_013008.1 ClpXP protease specificity-enhancing factor 4169820 sspB 8218763 sspB Escherichia coli O157:H7 str. TW14359 ClpXP protease specificity-enhancing factor YP_003080008.1 4169323 R 544404 CDS YP_003080009.1 254795172 8218764 complement(4169826..4170464) 1 NC_013008.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 4170464 sspA 8218764 sspA Escherichia coli O157:H7 str. TW14359 stringent starvation protein A YP_003080009.1 4169826 R 544404 CDS YP_003080010.1 254795173 8218765 complement(4170859..4171251) 1 NC_013008.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 4171251 rpsI 8218765 rpsI Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S9 YP_003080010.1 4170859 R 544404 CDS YP_003080011.1 254795174 8218766 complement(4171267..4171695) 1 NC_013008.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 4171695 rplM 8218766 rplM Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L13 YP_003080011.1 4171267 R 544404 CDS YP_003080012.1 254795175 8218767 complement(4171914..4173041) 1 NC_013008.1 hypothetical protein 4173041 yhcM 8218767 yhcM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080012.1 4171914 R 544404 CDS YP_003080013.1 254795176 8218768 4173235..4173633 1 NC_013008.1 cytochrome d ubiquinol oxidase subunit III 4173633 yhcB 8218768 yhcB Escherichia coli O157:H7 str. TW14359 cytochrome d ubiquinol oxidase subunit III YP_003080013.1 4173235 D 544404 CDS YP_003080014.1 254795177 8218769 4173787..4175154 1 NC_013008.1 serine endoprotease 4175154 degQ 8218769 degQ Escherichia coli O157:H7 str. TW14359 serine endoprotease YP_003080014.1 4173787 D 544404 CDS YP_003080015.1 254795178 8218770 4175244..4176311 1 NC_013008.1 serine endoprotease 4176311 degS 8218770 degS Escherichia coli O157:H7 str. TW14359 serine endoprotease YP_003080015.1 4175244 D 544404 CDS YP_003080016.1 254795179 8218771 complement(4176375..4177313) 1 NC_013008.1 oxidizes malate to oxaloacetate; malate dehydrogenase 4177313 mdh 8218771 mdh Escherichia coli O157:H7 str. TW14359 malate dehydrogenase YP_003080016.1 4176375 R 544404 CDS YP_003080017.1 254795180 8218772 4177748..4178218 1 NC_013008.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 4178218 argR 8218772 argR Escherichia coli O157:H7 str. TW14359 arginine repressor ArgR YP_003080017.1 4177748 D 544404 CDS YP_003080018.1 254795181 8218773 4178583..4178846 1 NC_013008.1 hypothetical protein 4178846 yhcN 8218773 yhcN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080018.1 4178583 D 544404 CDS YP_003080019.1 254795182 8218774 complement(4178902..4179174) 1 NC_013008.1 barnase inhibitor 4179174 yhcO 8218774 yhcO Escherichia coli O157:H7 str. TW14359 barnase inhibitor YP_003080019.1 4178902 R 544404 CDS YP_003080020.1 254795183 8218775 complement(4179266..4181233) 1 NC_013008.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 4181233 aaeB 8218775 aaeB Escherichia coli O157:H7 str. TW14359 p-hydroxybenzoic acid efflux subunit AaeB YP_003080020.1 4179266 R 544404 CDS YP_003080021.1 254795184 8218776 complement(4181239..4182168) 1 NC_013008.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 4182168 aaeA 8218776 aaeA Escherichia coli O157:H7 str. TW14359 p-hydroxybenzoic acid efflux subunit AaeA YP_003080021.1 4181239 R 544404 CDS YP_003080022.1 254795185 8218777 complement(4182176..4182379) 1 NC_013008.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 4182379 aaeX 8218777 aaeX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080022.1 4182176 R 544404 CDS YP_003080023.1 254795186 8218778 4182562..4183491 1 NC_013008.1 DNA-binding transcriptional regulator 4183491 aaeR 8218778 aaeR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080023.1 4182562 D 544404 CDS YP_003080024.1 254795187 8218779 complement(4183625..4185070) 1 NC_013008.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 4185070 tldD 8218779 tldD Escherichia coli O157:H7 str. TW14359 protease TldD YP_003080024.1 4183625 R 544404 CDS YP_003080025.1 254795188 8218780 complement(4185226..4189026) 1 NC_013008.1 hypothetical protein 4189026 yhdP 8218780 yhdP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080025.1 4185226 R 544404 CDS YP_003080026.1 254795189 8218781 complement(4189094..4190563) 1 NC_013008.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 4190563 rng 8218781 rng Escherichia coli O157:H7 str. TW14359 ribonuclease G YP_003080026.1 4189094 R 544404 CDS YP_003080027.1 254795190 8218782 complement(4190553..4191146) 1 NC_013008.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 4191146 yhdE 8218782 yhdE Escherichia coli O157:H7 str. TW14359 Maf-like protein YP_003080027.1 4190553 R 544404 CDS YP_003080028.1 254795191 8218783 complement(4191155..4191643) 1 NC_013008.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 4191643 mreD 8218783 mreD Escherichia coli O157:H7 str. TW14359 rod shape-determining protein MreD YP_003080028.1 4191155 R 544404 CDS YP_003080029.1 254795192 8218784 complement(4191643..4192746) 1 NC_013008.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 4192746 mreC 8218784 mreC Escherichia coli O157:H7 str. TW14359 rod shape-determining protein MreC YP_003080029.1 4191643 R 544404 CDS YP_003080030.1 254795193 8218785 complement(4192812..4193855) 1 NC_013008.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 4193855 mreB 8218785 mreB Escherichia coli O157:H7 str. TW14359 rod shape-determining protein MreB YP_003080030.1 4192812 R 544404 CDS YP_003080031.1 254795194 8218786 complement(4194160..4196100) 1 NC_013008.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 4196100 yhdA 8218786 yhdA Escherichia coli O157:H7 str. TW14359 regulatory protein CsrD YP_003080031.1 4194160 R 544404 CDS YP_003080032.1 254795195 8218787 4196252..4197226 1 NC_013008.1 oxidoreductase 4197226 yhdH 8218787 yhdH Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003080032.1 4196252 D 544404 CDS YP_003080033.1 254795196 8218788 4197263..4197427 1 NC_013008.1 initiation of DNA replication 4197427 8218788 ECSP_4222 Escherichia coli O157:H7 str. TW14359 initiation of DNA replication YP_003080033.1 4197263 D 544404 CDS YP_003080034.1 254795197 8218789 4197512..4197631 1 NC_013008.1 hypothetical protein 4197631 8218789 ECSP_4223 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080034.1 4197512 D 544404 CDS YP_003080035.1 254795198 8218790 4198204..4198674 1 NC_013008.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 4198674 accB 8218790 accB Escherichia coli O157:H7 str. TW14359 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_003080035.1 4198204 D 544404 CDS YP_003080036.1 254795199 8218791 4198685..4200034 1 NC_013008.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 4200034 accC 8218791 accC Escherichia coli O157:H7 str. TW14359 acetyl-CoA carboxylase biotin carboxylase subunit YP_003080036.1 4198685 D 544404 CDS YP_003080037.1 254795200 8218792 4200143..4200385 1 NC_013008.1 hypothetical protein 4200385 yhdT 8218792 yhdT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080037.1 4200143 D 544404 CDS YP_003080038.1 254795201 8218793 4200375..4201826 1 NC_013008.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 4201826 panF 8218793 panF Escherichia coli O157:H7 str. TW14359 sodium/panthothenate symporter YP_003080038.1 4200375 D 544404 CDS YP_003080039.1 254795202 8218794 4201838..4202719 1 NC_013008.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 4202719 prmA 8218794 prmA Escherichia coli O157:H7 str. TW14359 ribosomal protein L11 methyltransferase YP_003080039.1 4201838 D 544404 CDS YP_003080040.1 254795203 8218795 4203048..4204013 1 NC_013008.1 tRNA-dihydrouridine synthase B 4204013 dusB 8218795 dusB Escherichia coli O157:H7 str. TW14359 tRNA-dihydrouridine synthase B YP_003080040.1 4203048 D 544404 CDS YP_003080041.1 254795204 8218796 4204039..4204335 1 NC_013008.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 4204335 fis 8218796 fis Escherichia coli O157:H7 str. TW14359 DNA-binding protein Fis YP_003080041.1 4204039 D 544404 CDS YP_003080042.1 254795205 8218797 4204420..4205304 1 NC_013008.1 methyltransferase 4205304 yhdJ 8218797 yhdJ Escherichia coli O157:H7 str. TW14359 methyltransferase YP_003080042.1 4204420 D 544404 CDS YP_003080043.1 254795206 8218798 4205388..4205567 1 NC_013008.1 hypothetical protein 4205567 yhdU 8218798 yhdU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080043.1 4205388 D 544404 CDS YP_003080044.1 254795207 8218799 complement(4205570..4206232) 1 NC_013008.1 DNA-binding transcriptional regulator EnvR 4206232 envR 8218799 envR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator EnvR YP_003080044.1 4205570 R 544404 CDS YP_003080045.1 254795208 8218800 4206631..4207788 1 NC_013008.1 cytoplasmic membrane lipoprotein 4207788 acrE 8218800 acrE Escherichia coli O157:H7 str. TW14359 cytoplasmic membrane lipoprotein YP_003080045.1 4206631 D 544404 CDS YP_003080046.1 254795209 8218802 4211202..4211423 1 NC_013008.1 outer membrane protein 4211423 yhdV 8218802 yhdV Escherichia coli O157:H7 str. TW14359 outer membrane protein YP_003080046.1 4211202 D 544404 CDS YP_003080047.1 254795210 8218803 4211854..4212879 1 NC_013008.1 periplasmic-binding component of an ABC superfamily amino acid transporter 4212879 yhdW 8218803 yhdW Escherichia coli O157:H7 str. TW14359 periplasmic-binding component of an ABC superfamily amino acid transporter YP_003080047.1 4211854 D 544404 CDS YP_003080048.1 254795211 8218804 4212947..4214128 1 NC_013008.1 amino-acid ABC transporter membrane protein 4214128 yhdX 8218804 yhdX Escherichia coli O157:H7 str. TW14359 amino-acid ABC transporter membrane protein YP_003080048.1 4212947 D 544404 CDS YP_003080049.1 254795212 8218805 4214138..4215226 1 NC_013008.1 amino-acid ABC transporter membrane protein 4215226 yhdY 8218805 yhdY Escherichia coli O157:H7 str. TW14359 amino-acid ABC transporter membrane protein YP_003080049.1 4214138 D 544404 CDS YP_003080050.1 254795213 8218806 4215252..4215578 1 NC_013008.1 transposase 4215578 8218806 ECSP_4240 Escherichia coli O157:H7 str. TW14359 transposase YP_003080050.1 4215252 D 544404 CDS YP_003080051.1 254795214 8218807 4215575..4216465 1 NC_013008.1 transposase 4216465 8218807 ECSP_4241 Escherichia coli O157:H7 str. TW14359 transposase YP_003080051.1 4215575 D 544404 CDS YP_003080052.1 254795215 8218808 4216562..4217320 1 NC_013008.1 amino-acid transporter subunit, ATP-binding protein of ABC superfamily 4217320 yhdZ 8218808 yhdZ Escherichia coli O157:H7 str. TW14359 amino-acid transporter subunit, ATP-binding protein of ABC superfamily YP_003080052.1 4216562 D 544404 CDS YP_003080053.1 254795216 8218816 4223042..4223923 1 NC_013008.1 hypothetical protein 4223923 yrdA 8218816 yrdA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080053.1 4223042 D 544404 CDS YP_003080054.1 254795217 8218817 complement(4223899..4224156) 1 NC_013008.1 hypothetical protein 4224156 yrdB 8218817 yrdB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080054.1 4223899 R 544404 CDS YP_003080055.1 254795218 8218818 complement(4224153..4224971) 1 NC_013008.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 4224971 aroE 8218818 aroE Escherichia coli O157:H7 str. TW14359 shikimate 5-dehydrogenase YP_003080055.1 4224153 R 544404 CDS YP_003080056.1 254795219 8218819 complement(4224976..4225548) 1 NC_013008.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 4225548 yrdC 8218819 yrdC Escherichia coli O157:H7 str. TW14359 ribosome maturation factor YP_003080056.1 4224976 R 544404 CDS YP_003080057.1 254795220 8218820 complement(4225553..4226095) 1 NC_013008.1 DNA topoisomerase 4226095 yrdD 8218820 yrdD Escherichia coli O157:H7 str. TW14359 DNA topoisomerase YP_003080057.1 4225553 R 544404 CDS YP_003080058.1 254795221 8218821 complement(4226124..4226597) 1 NC_013008.1 hypothetical protein 4226597 smg 8218821 smg Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080058.1 4226124 R 544404 CDS YP_003080059.1 254795222 8218822 complement(4226569..4227693) 1 NC_013008.1 DNA protecting protein DprA 4227693 smf 8218822 smf Escherichia coli O157:H7 str. TW14359 DNA protecting protein DprA YP_003080059.1 4226569 R 544404 CDS YP_003080060.1 254795223 8218823 4227823..4228332 1 NC_013008.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4228332 def 8218823 def Escherichia coli O157:H7 str. TW14359 peptide deformylase YP_003080060.1 4227823 D 544404 CDS YP_003080061.1 254795224 8218824 4228347..4229294 1 NC_013008.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 4229294 fmt 8218824 fmt Escherichia coli O157:H7 str. TW14359 methionyl-tRNA formyltransferase YP_003080061.1 4228347 D 544404 CDS YP_003080062.1 254795225 8218825 4229340..4230629 1 NC_013008.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 4230629 rsmB 8218825 rsmB Escherichia coli O157:H7 str. TW14359 16S rRNA methyltransferase GidB YP_003080062.1 4229340 D 544404 CDS YP_003080063.1 254795226 8218826 4230651..4232027 1 NC_013008.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 4232027 trkA 8218826 trkA Escherichia coli O157:H7 str. TW14359 potassium transporter peripheral membrane component YP_003080063.1 4230651 D 544404 CDS YP_003080064.1 254795227 8218827 4232157..4232567 1 NC_013008.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 4232567 mscL 8218827 mscL Escherichia coli O157:H7 str. TW14359 large-conductance mechanosensitive channel YP_003080064.1 4232157 D 544404 CDS YP_003080065.1 254795228 8218828 complement(4232564..4232782) 1 NC_013008.1 hypothetical protein 4232782 yhdL 8218828 yhdL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080065.1 4232564 R 544404 CDS YP_003080066.1 254795229 8218829 complement(4232838..4233263) 1 NC_013008.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 4233263 zntR 8218829 zntR Escherichia coli O157:H7 str. TW14359 zinc-responsive transcriptional regulator YP_003080066.1 4232838 R 544404 CDS YP_003080067.1 254795230 8218830 complement(4233274..4233642) 1 NC_013008.1 hypothetical protein 4233642 yhdN 8218830 yhdN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080067.1 4233274 R 544404 CDS YP_003080068.1 254795231 8218831 complement(4233749..4234132) 1 NC_013008.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 4234132 rplQ 8218831 rplQ Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L17 YP_003080068.1 4233749 R 544404 CDS YP_003080069.1 254795232 8218832 complement(4234173..4235162) 1 NC_013008.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 4235162 rpoA 8218832 rpoA Escherichia coli O157:H7 str. TW14359 DNA-directed RNA polymerase subunit alpha YP_003080069.1 4234173 R 544404 CDS YP_003080070.1 254795233 8218833 complement(4235188..4235808) 1 NC_013008.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 4235808 rpsD 8218833 rpsD Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S4 YP_003080070.1 4235188 R 544404 CDS YP_003080071.1 254795234 8218834 complement(4235842..4236231) 1 NC_013008.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 4236231 rpsK 8218834 rpsK Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S11 YP_003080071.1 4235842 R 544404 CDS YP_003080072.1 254795235 8218835 complement(4236248..4236604) 1 NC_013008.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 4236604 rpsM 8218835 rpsM Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S13 YP_003080072.1 4236248 R 544404 CDS YP_003080073.1 254795236 8218836 complement(4236751..4236867) 1 NC_013008.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 4236867 rpmJ 8218836 rpmJ Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L36 YP_003080073.1 4236751 R 544404 CDS YP_003080074.1 254795237 8218837 complement(4236899..4238230) 1 NC_013008.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 4238230 secY 8218837 secY Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecY YP_003080074.1 4236899 R 544404 CDS YP_003080075.1 254795238 8218838 complement(4238238..4238672) 1 NC_013008.1 late assembly protein; 50S ribosomal protein L15 4238672 rplO 8218838 rplO Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L15 YP_003080075.1 4238238 R 544404 CDS YP_003080076.1 254795239 8218839 complement(4238676..4238855) 1 NC_013008.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 4238855 rpmD 8218839 rpmD Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L30 YP_003080076.1 4238676 R 544404 CDS YP_003080077.1 254795240 8218840 complement(4238859..4239362) 1 NC_013008.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 4239362 rpsE 8218840 rpsE Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S5 YP_003080077.1 4238859 R 544404 CDS YP_003080078.1 254795241 8218841 complement(4239377..4239730) 1 NC_013008.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 4239730 rplR 8218841 rplR Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L18 YP_003080078.1 4239377 R 544404 CDS YP_003080079.1 254795242 8218842 complement(4239740..4240273) 1 NC_013008.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 4240273 rplF 8218842 rplF Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L6 YP_003080079.1 4239740 R 544404 CDS YP_003080080.1 254795243 8218843 complement(4240286..4240678) 1 NC_013008.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 4240678 rpsH 8218843 rpsH Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S8 YP_003080080.1 4240286 R 544404 CDS YP_003080081.1 254795244 8218844 complement(4240712..4241017) 1 NC_013008.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 4241017 rpsN 8218844 rpsN Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S14 YP_003080081.1 4240712 R 544404 CDS YP_003080082.1 254795245 8218845 complement(4241032..4241571) 1 NC_013008.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 4241571 rplE 8218845 rplE Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L5 YP_003080082.1 4241032 R 544404 CDS YP_003080083.1 254795246 8218846 complement(4241586..4241900) 1 NC_013008.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 4241900 rplX 8218846 rplX Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L24 YP_003080083.1 4241586 R 544404 CDS YP_003080084.1 254795247 8218847 complement(4241911..4242282) 1 NC_013008.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 4242282 rplN 8218847 rplN Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L14 YP_003080084.1 4241911 R 544404 CDS YP_003080085.1 254795248 8218848 complement(4242447..4242701) 1 NC_013008.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 4242701 rpsQ 8218848 rpsQ Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S17 YP_003080085.1 4242447 R 544404 CDS YP_003080086.1 254795249 8218849 complement(4242701..4242892) 1 NC_013008.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 4242892 rpmC 8218849 rpmC Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L29 YP_003080086.1 4242701 R 544404 CDS YP_003080087.1 254795250 8218850 complement(4242892..4243302) 1 NC_013008.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 4243302 rplP 8218850 rplP Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L16 YP_003080087.1 4242892 R 544404 CDS YP_003080088.1 254795251 8218851 complement(4243315..4244016) 1 NC_013008.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 4244016 rpsC 8218851 rpsC Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S3 YP_003080088.1 4243315 R 544404 CDS YP_003080089.1 254795252 8218852 complement(4244034..4244366) 1 NC_013008.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 4244366 rplV 8218852 rplV Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L22 YP_003080089.1 4244034 R 544404 CDS YP_003080090.1 254795253 8218853 complement(4244381..4244659) 1 NC_013008.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 4244659 rpsS 8218853 rpsS Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S19 YP_003080090.1 4244381 R 544404 CDS YP_003080091.1 254795254 8218854 complement(4244676..4245497) 1 NC_013008.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 4245497 rplB 8218854 rplB Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L2 YP_003080091.1 4244676 R 544404 CDS YP_003080092.1 254795255 8218855 complement(4245515..4245817) 1 NC_013008.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 4245817 rplW 8218855 rplW Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L23 YP_003080092.1 4245515 R 544404 CDS YP_003080093.1 254795256 8218856 complement(4245814..4246419) 1 NC_013008.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 4246419 rplD 8218856 rplD Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L4 YP_003080093.1 4245814 R 544404 CDS YP_003080094.1 254795257 8218857 complement(4246430..4247059) 1 NC_013008.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 4247059 rplC 8218857 rplC Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L3 YP_003080094.1 4246430 R 544404 CDS YP_003080095.1 254795258 8218858 complement(4247092..4247403) 1 NC_013008.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 4247403 rpsJ 8218858 rpsJ Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S10 YP_003080095.1 4247092 R 544404 CDS YP_003080096.1 254795259 8218859 4247782..4248249 1 NC_013008.1 leader peptidase 4248249 hopD 8218859 hopD Escherichia coli O157:H7 str. TW14359 leader peptidase YP_003080096.1 4247782 D 544404 CDS YP_003080097.1 254795260 8218860 complement(4248246..4248722) 1 NC_013008.1 iron storage protein; bacterioferritin 4248722 bfr 8218860 bfr Escherichia coli O157:H7 str. TW14359 bacterioferritin YP_003080097.1 4248246 R 544404 CDS YP_003080098.1 254795261 8218861 complement(4248795..4248989) 1 NC_013008.1 bacterioferritin-associated ferredoxin 4248989 bfd 8218861 bfd Escherichia coli O157:H7 str. TW14359 bacterioferritin-associated ferredoxin YP_003080098.1 4248795 R 544404 CDS YP_003080099.1 254795262 8218862 complement(4249172..4250356) 1 NC_013008.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4250356 tufA 8218862 tufA Escherichia coli O157:H7 str. TW14359 elongation factor Tu YP_003080099.1 4249172 R 544404 CDS YP_003080100.1 254795263 8218863 complement(4250427..4252541) 1 NC_013008.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 4252541 fusA 8218863 fusA Escherichia coli O157:H7 str. TW14359 elongation factor G YP_003080100.1 4250427 R 544404 CDS YP_003080101.1 254795264 8218864 complement(4252638..4253108) 1 NC_013008.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 4253108 rpsG 8218864 rpsG Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S7 YP_003080101.1 4252638 R 544404 CDS YP_003080102.1 254795265 8218865 complement(4253205..4253579) 1 NC_013008.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 4253579 rpsL 8218865 rpsL Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S12 YP_003080102.1 4253205 R 544404 CDS YP_003080103.1 254795266 8218866 complement(4253705..4253992) 1 NC_013008.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 4253992 yheL 8218866 yheL Escherichia coli O157:H7 str. TW14359 sulfur transfer complex subunit TusB YP_003080103.1 4253705 R 544404 CDS YP_003080104.1 254795267 8218867 complement(4254000..4254359) 1 NC_013008.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 4254359 yheM 8218867 yheM Escherichia coli O157:H7 str. TW14359 sulfur relay protein TusC YP_003080104.1 4254000 R 544404 CDS YP_003080105.1 254795268 8218868 complement(4254359..4254745) 1 NC_013008.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 4254745 yheN 8218868 yheN Escherichia coli O157:H7 str. TW14359 sulfur transfer complex subunit TusD YP_003080105.1 4254359 R 544404 CDS YP_003080106.1 254795269 8218869 complement(4254745..4255467) 1 NC_013008.1 DNA-binding transcriptional regulator 4255467 yheO 8218869 yheO Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080106.1 4254745 R 544404 CDS YP_003080107.1 254795270 8218870 complement(4255634..4256446) 1 NC_013008.1 rotamase; FKBP-type peptidylprolyl isomerase 4256446 fkpA 8218870 fkpA Escherichia coli O157:H7 str. TW14359 FKBP-type peptidylprolyl isomerase YP_003080107.1 4255634 R 544404 CDS YP_003080108.1 254795271 8218871 4256667..4256885 1 NC_013008.1 hypothetical protein 4256885 slyX 8218871 slyX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080108.1 4256667 D 544404 CDS YP_003080109.1 254795272 8218872 complement(4256934..4257524) 1 NC_013008.1 rotamase; FKBP-type peptidylprolyl isomerase 4257524 slyD 8218872 slyD Escherichia coli O157:H7 str. TW14359 FKBP-type peptidylprolyl isomerase YP_003080109.1 4256934 R 544404 CDS YP_003080110.1 254795273 8218873 complement(4257619..4257819) 1 NC_013008.1 hypothetical protein 4257819 yheV 8218873 yheV Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080110.1 4257619 R 544404 CDS YP_003080111.1 254795274 8218874 complement(4257856..4259634) 1 NC_013008.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 4259634 kefB 8218874 kefB Escherichia coli O157:H7 str. TW14359 glutathione-regulated potassium-efflux system protein KefB YP_003080111.1 4257856 R 544404 CDS YP_003080112.1 254795275 8218875 complement(4259634..4260188) 1 NC_013008.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 4260188 kefG 8218875 kefG Escherichia coli O157:H7 str. TW14359 glutathione-regulated potassium-efflux system ancillary protein KefG YP_003080112.1 4259634 R 544404 CDS YP_003080113.1 254795276 8218876 4260316..4262229 1 NC_013008.1 ABC transporter ATP-binding protein 4262229 yheS 8218876 yheS Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YP_003080113.1 4260316 D 544404 CDS YP_003080114.1 254795277 8218877 4262229..4263251 1 NC_013008.1 hydrolase 4263251 yheT 8218877 yheT Escherichia coli O157:H7 str. TW14359 hydrolase YP_003080114.1 4262229 D 544404 CDS YP_003080115.1 254795278 8218878 4263245..4263463 1 NC_013008.1 hypothetical protein 4263463 yheU 8218878 yheU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080115.1 4263245 D 544404 CDS YP_003080116.1 254795279 8218879 4263517..4264386 1 NC_013008.1 phosphoribulokinase 4264386 prkB 8218879 prkB Escherichia coli O157:H7 str. TW14359 phosphoribulokinase YP_003080116.1 4263517 D 544404 CDS YP_003080117.1 254795280 8218880 complement(4264441..4264845) 1 NC_013008.1 hypothetical protein 4264845 yhfA 8218880 yhfA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080117.1 4264441 R 544404 CDS YP_003080118.1 254795281 8218881 4265147..4265779 1 NC_013008.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 4265779 crp 8218881 crp Escherichia coli O157:H7 str. TW14359 cAMP-regulatory protein YP_003080118.1 4265147 D 544404 CDS YP_003080119.1 254795282 8218882 4265818..4267920 1 NC_013008.1 hypothetical protein 4267920 yhfK 8218882 yhfK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080119.1 4265818 D 544404 CDS YP_003080120.1 254795283 8218883 complement(4267987..4269207) 1 NC_013008.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 4269207 argD 8218883 argD Escherichia coli O157:H7 str. TW14359 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_003080120.1 4267987 R 544404 CDS YP_003080121.1 254795284 8218884 complement(4269293..4269856) 1 NC_013008.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 4269856 pabA 8218884 pabA Escherichia coli O157:H7 str. TW14359 para-aminobenzoate synthase component II YP_003080121.1 4269293 R 544404 CDS YP_003080122.1 254795285 8218885 complement(4269888..4270490) 1 NC_013008.1 cell filamentation protein Fic 4270490 fic 8218885 fic Escherichia coli O157:H7 str. TW14359 cell filamentation protein Fic YP_003080122.1 4269888 R 544404 CDS YP_003080123.1 254795286 8218886 complement(4270480..4270647) 1 NC_013008.1 hypothetical protein 4270647 yhfG 8218886 yhfG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080123.1 4270480 R 544404 CDS YP_003080124.1 254795287 8218887 complement(4270752..4271324) 1 NC_013008.1 peptidyl-prolyl cis-trans isomerase A 4271324 ppiA 8218887 ppiA Escherichia coli O157:H7 str. TW14359 peptidyl-prolyl cis-trans isomerase A YP_003080124.1 4270752 R 544404 CDS YP_003080125.1 254795288 8218888 4271595..4272776 1 NC_013008.1 hypothetical protein 4272776 tsgA 8218888 tsgA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080125.1 4271595 D 544404 CDS YP_003080126.1 254795289 8218889 4273038..4275581 1 NC_013008.1 nitrite reductase, large subunit, NAD(P)H-binding 4275581 nirB 8218889 nirB Escherichia coli O157:H7 str. TW14359 nitrite reductase, large subunit, NAD(P)H-binding YP_003080126.1 4273038 D 544404 CDS YP_003080127.1 254795290 8218890 4275578..4275904 1 NC_013008.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 4275904 nirD 8218890 nirD Escherichia coli O157:H7 str. TW14359 nitrite reductase small subunit YP_003080127.1 4275578 D 544404 CDS YP_003080128.1 254795291 8218891 4276030..4276836 1 NC_013008.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 4276836 nirC 8218891 nirC Escherichia coli O157:H7 str. TW14359 nitrite transporter NirC YP_003080128.1 4276030 D 544404 CDS YP_003080129.1 254795292 8218892 4276855..4278228 1 NC_013008.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 4278228 cysG 8218892 cysG Escherichia coli O157:H7 str. TW14359 siroheme synthase YP_003080129.1 4276855 D 544404 CDS YP_003080130.1 254795293 8218893 4278483..4278650 1 NC_013008.1 hypothetical protein 4278650 yhfL 8218893 yhfL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080130.1 4278483 D 544404 CDS YP_003080131.1 254795294 8218894 4278946..4280283 1 NC_013008.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; fructoselysine transporter 4280283 frlA 8218894 frlA Escherichia coli O157:H7 str. TW14359 fructoselysine transporter YP_003080131.1 4278946 D 544404 CDS YP_003080132.1 254795295 8218895 4280304..4281326 1 NC_013008.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 4281326 frlB 8218895 frlB Escherichia coli O157:H7 str. TW14359 fructoselysine-6-P-deglycase YP_003080132.1 4280304 D 544404 CDS YP_003080133.1 254795296 8218896 4281377..4282204 1 NC_013008.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 4282204 frlC 8218896 frlC Escherichia coli O157:H7 str. TW14359 fructoselysine 3-epimerase YP_003080133.1 4281377 D 544404 CDS YP_003080134.1 254795297 8218898 4283089..4283820 1 NC_013008.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 4283820 frlR 8218898 frlR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator FrlR YP_003080134.1 4283089 D 544404 CDS YP_003080135.1 254795298 8218899 complement(4283951..4284955) 1 NC_013008.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 4284955 trpS 8218899 trpS Escherichia coli O157:H7 str. TW14359 tryptophanyl-tRNA synthetase YP_003080135.1 4283951 R 544404 CDS YP_003080136.1 254795299 8218900 complement(4284948..4285706) 1 NC_013008.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 4285706 gph 8218900 gph Escherichia coli O157:H7 str. TW14359 phosphoglycolate phosphatase YP_003080136.1 4284948 R 544404 CDS YP_003080137.1 254795300 8218901 complement(4285699..4286376) 1 NC_013008.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 4286376 rpe 8218901 rpe Escherichia coli O157:H7 str. TW14359 ribulose-phosphate 3-epimerase YP_003080137.1 4285699 R 544404 CDS YP_003080138.1 254795301 8218902 complement(4286394..4287230) 1 NC_013008.1 DNA adenine methylase 4287230 dam 8218902 dam Escherichia coli O157:H7 str. TW14359 DNA adenine methylase YP_003080138.1 4286394 R 544404 CDS YP_003080139.1 254795302 8218903 complement(4287337..4288623) 1 NC_013008.1 hypothetical protein 4288623 damX 8218903 damX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080139.1 4287337 R 544404 CDS YP_003080140.1 254795303 8218904 complement(4288715..4289803) 1 NC_013008.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 4289803 aroB 8218904 aroB Escherichia coli O157:H7 str. TW14359 3-dehydroquinate synthase YP_003080140.1 4288715 R 544404 CDS YP_003080141.1 254795304 8218905 complement(4289860..4290381) 1 NC_013008.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 4290381 aroK 8218905 aroK Escherichia coli O157:H7 str. TW14359 shikimate kinase I YP_003080141.1 4289860 R 544404 CDS YP_003080142.1 254795305 8218906 complement(4290782..4292020) 1 NC_013008.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 4292020 hofQ 8218906 hofQ Escherichia coli O157:H7 str. TW14359 outer membrane porin HofQ YP_003080142.1 4290782 R 544404 CDS YP_003080143.1 254795306 8218907 complement(4291932..4292336) 1 NC_013008.1 hypothetical protein 4292336 yrfA 8218907 yrfA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080143.1 4291932 R 544404 CDS YP_003080144.1 254795307 8218908 complement(4292326..4292766) 1 NC_013008.1 hypothetical protein 4292766 yrfB 8218908 yrfB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080144.1 4292326 R 544404 CDS YP_003080145.1 254795308 8218909 complement(4292750..4293289) 1 NC_013008.1 fimbrial assembly protein 4293289 yrfC 8218909 yrfC Escherichia coli O157:H7 str. TW14359 fimbrial assembly protein YP_003080145.1 4292750 R 544404 CDS YP_003080146.1 254795309 8218910 complement(4293273..4294067) 1 NC_013008.1 pilus assembly protein 4294067 yrfD 8218910 yrfD Escherichia coli O157:H7 str. TW14359 pilus assembly protein YP_003080146.1 4293273 R 544404 CDS YP_003080147.1 254795310 8218911 4294187..4296739 1 NC_013008.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 4296739 mrcA 8218911 mrcA Escherichia coli O157:H7 str. TW14359 peptidoglycan synthetase YP_003080147.1 4294187 D 544404 CDS YP_003080148.1 254795311 8218912 complement(4296904..4297464) 1 NC_013008.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 4297464 nudE 8218912 nudE Escherichia coli O157:H7 str. TW14359 ADP-ribose diphosphatase NudE YP_003080148.1 4296904 R 544404 CDS YP_003080149.1 254795312 8218913 4297784..4299919 1 NC_013008.1 inner membrane protein 4299919 yrfF 8218913 yrfF Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080149.1 4297784 D 544404 CDS YP_003080150.1 254795313 8218914 4299984..4300652 1 NC_013008.1 hydrolase 4300652 yrfG 8218914 yrfG Escherichia coli O157:H7 str. TW14359 hydrolase YP_003080150.1 4299984 D 544404 CDS YP_003080151.1 254795314 8218915 4300663..4301064 1 NC_013008.1 ribosome-associated heat shock protein Hsp15 4301064 hslR 8218915 hslR Escherichia coli O157:H7 str. TW14359 ribosome-associated heat shock protein Hsp15 YP_003080151.1 4300663 D 544404 CDS YP_003080152.1 254795315 8218916 4301089..4301967 1 NC_013008.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 4301967 hslO 8218916 hslO Escherichia coli O157:H7 str. TW14359 Hsp33-like chaperonin YP_003080152.1 4301089 D 544404 CDS YP_003080153.1 254795316 8218917 complement(4302030..4303754) 1 NC_013008.1 inner membrane protein 4303754 yhgE 8218917 yhgE Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080153.1 4302030 R 544404 CDS YP_003080154.1 254795317 8218918 complement(4303830..4303961) 1 NC_013008.1 hypothetical protein 4303961 8218918 ECSP_4352 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080154.1 4303830 R 544404 CDS YP_003080155.1 254795318 8218919 4304133..4305755 1 NC_013008.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 4305755 pck 8218919 pck Escherichia coli O157:H7 str. TW14359 phosphoenolpyruvate carboxykinase YP_003080155.1 4304133 D 544404 CDS YP_003080156.1 254795319 8218920 complement(4305831..4307183) 1 NC_013008.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 4307183 envZ 8218920 envZ Escherichia coli O157:H7 str. TW14359 osmolarity sensor protein YP_003080156.1 4305831 R 544404 CDS YP_003080157.1 254795320 8218921 complement(4307180..4307899) 1 NC_013008.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 4307899 ompR 8218921 ompR Escherichia coli O157:H7 str. TW14359 osmolarity response regulator YP_003080157.1 4307180 R 544404 CDS YP_003080158.1 254795321 8218922 4308127..4308603 1 NC_013008.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 4308603 greB 8218922 greB Escherichia coli O157:H7 str. TW14359 transcription elongation factor GreB YP_003080158.1 4308127 D 544404 CDS YP_003080159.1 254795322 8218923 4308700..4311021 1 NC_013008.1 transcriptional accessory protein 4311021 yhgF 8218923 yhgF Escherichia coli O157:H7 str. TW14359 transcriptional accessory protein YP_003080159.1 4308700 D 544404 CDS YP_003080160.1 254795323 8218924 4311459..4311686 1 NC_013008.1 ferrous iron transport protein A 4311686 feoA 8218924 feoA Escherichia coli O157:H7 str. TW14359 ferrous iron transport protein A YP_003080160.1 4311459 D 544404 CDS YP_003080161.1 254795324 8218925 4311703..4314024 1 NC_013008.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 4314024 feoB 8218925 feoB Escherichia coli O157:H7 str. TW14359 ferrous iron transport protein B YP_003080161.1 4311703 D 544404 CDS YP_003080162.1 254795325 8218926 4314024..4314260 1 NC_013008.1 DNA-binding transcriptional regulator 4314260 yhgG 8218926 yhgG Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080162.1 4314024 D 544404 CDS YP_003080163.1 254795326 8218927 4314463..4315341 1 NC_013008.1 hypothetical protein 4315341 yhgA 8218927 yhgA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080163.1 4314463 D 544404 CDS YP_003080164.1 254795327 8218928 complement(4315368..4316138) 1 NC_013008.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 4316138 bioH 8218928 bioH Escherichia coli O157:H7 str. TW14359 carboxylesterase BioH YP_003080164.1 4315368 R 544404 CDS YP_003080165.1 254795328 8218929 4316176..4316859 1 NC_013008.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 4316859 gntX 8218929 gntX Escherichia coli O157:H7 str. TW14359 gluconate periplasmic binding protein YP_003080165.1 4316176 D 544404 CDS YP_003080166.1 254795329 8218930 4316918..4317493 1 NC_013008.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 4317493 gntY 8218930 gntY Escherichia coli O157:H7 str. TW14359 DNA uptake protein YP_003080166.1 4316918 D 544404 CDS YP_003080167.1 254795330 8218931 4317854..4319170 1 NC_013008.1 gluconate transporter, high-affinity GNT I system 4319170 gntT 8218931 gntT Escherichia coli O157:H7 str. TW14359 gluconate transporter, high-affinity GNT I system YP_003080167.1 4317854 D 544404 CDS YP_003080168.1 254795331 8218932 complement(4319215..4321299) 1 NC_013008.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 4321299 malQ 8218932 malQ Escherichia coli O157:H7 str. TW14359 4-alpha-glucanotransferase YP_003080168.1 4319215 R 544404 CDS YP_003080169.1 254795332 8218933 complement(4321309..4323702) 1 NC_013008.1 maltodextrin phosphorylase 4323702 malP 8218933 malP Escherichia coli O157:H7 str. TW14359 maltodextrin phosphorylase YP_003080169.1 4321309 R 544404 CDS YP_003080170.1 254795333 8218934 complement(4323962..4324063) 1 NC_013008.1 hypothetical protein 4324063 8218934 ECSP_4368 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080170.1 4323962 R 544404 CDS YP_003080171.1 254795334 8218935 4324314..4327019 1 NC_013008.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 4327019 malT 8218935 malT Escherichia coli O157:H7 str. TW14359 transcriptional regulator MalT YP_003080171.1 4324314 D 544404 CDS YP_003080172.1 254795335 8218936 4327080..4327364 1 NC_013008.1 hypothetical protein 4327364 8218936 ECSP_4370 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080172.1 4327080 D 544404 CDS YP_003080173.1 254795336 8218937 4327355..4327840 1 NC_013008.1 hypothetical protein 4327840 8218937 ECSP_4371 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080173.1 4327355 D 544404 CDS YP_003080174.1 254795337 8218938 complement(4327890..4328918) 1 NC_013008.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 4328918 rtcA 8218938 rtcA Escherichia coli O157:H7 str. TW14359 RNA 3'-terminal-phosphate cyclase YP_003080174.1 4327890 R 544404 CDS YP_003080175.1 254795338 8218939 complement(4328922..4330148) 1 NC_013008.1 hypothetical protein 4330148 rtcB 8218939 rtcB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080175.1 4328922 R 544404 CDS YP_003080176.1 254795339 8218940 4330336..4331934 1 NC_013008.1 sigma 54-dependent transcriptional regulator of rtcBA expression 4331934 rtcR 8218940 rtcR Escherichia coli O157:H7 str. TW14359 sigma 54-dependent transcriptional regulator of rtcBA expression YP_003080176.1 4330336 D 544404 CDS YP_003080177.1 254795340 8218941 complement(4331916..4332674) 1 NC_013008.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 4332674 glpR 8218941 glpR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor GlpR YP_003080177.1 4331916 R 544404 CDS YP_003080178.1 254795341 8218942 complement(4332691..4333521) 1 NC_013008.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 4333521 glpG 8218942 glpG Escherichia coli O157:H7 str. TW14359 intramembrane serine protease GlpG YP_003080178.1 4332691 R 544404 CDS YP_003080179.1 254795342 8218943 complement(4333566..4333892) 1 NC_013008.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 4333892 glpE 8218943 glpE Escherichia coli O157:H7 str. TW14359 thiosulfate sulfurtransferase YP_003080179.1 4333566 R 544404 CDS YP_003080180.1 254795343 8218944 4334082..4335587 1 NC_013008.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 4335587 glpD 8218944 glpD Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate dehydrogenase YP_003080180.1 4334082 D 544404 CDS YP_003080181.1 254795344 8218945 complement(4335802..4336401) 1 NC_013008.1 hypothetical protein 4336401 8218945 ECSP_4379 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080181.1 4335802 R 544404 CDS YP_003080182.1 254795345 8218946 complement(4336404..4337396) 1 NC_013008.1 hypothetical protein 4337396 8218946 ECSP_4380 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080182.1 4336404 R 544404 CDS YP_003080183.1 254795346 8218947 complement(4337422..4338930) 1 NC_013008.1 periplasmic-binding component of an ABC superfamily transporter 4338930 yzgL 8218947 yzgL Escherichia coli O157:H7 str. TW14359 periplasmic-binding component of an ABC superfamily transporter YP_003080183.1 4337422 R 544404 CDS YP_003080184.1 254795347 8218948 complement(4339055..4341502) 1 NC_013008.1 glycogen phosphorylase 4341502 glgP 8218948 glgP Escherichia coli O157:H7 str. TW14359 glycogen phosphorylase YP_003080184.1 4339055 R 544404 CDS YP_003080185.1 254795348 8218949 complement(4341521..4342954) 1 NC_013008.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 4342954 glgA 8218949 glgA Escherichia coli O157:H7 str. TW14359 glycogen synthase YP_003080185.1 4341521 R 544404 CDS YP_003080186.1 254795349 8218950 complement(4342954..4344249) 1 NC_013008.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 4344249 glgC 8218950 glgC Escherichia coli O157:H7 str. TW14359 glucose-1-phosphate adenylyltransferase YP_003080186.1 4342954 R 544404 CDS YP_003080187.1 254795350 8218951 complement(4344267..4346240) 1 NC_013008.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme 4346240 glgX 8218951 glgX Escherichia coli O157:H7 str. TW14359 glycogen debranching enzyme YP_003080187.1 4344267 R 544404 CDS YP_003080188.1 254795351 8218952 complement(4346237..4348423) 1 NC_013008.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 4348423 glgB 8218952 glgB Escherichia coli O157:H7 str. TW14359 glycogen branching enzyme YP_003080188.1 4346237 R 544404 CDS YP_003080189.1 254795352 8218953 complement(4348696..4349799) 1 NC_013008.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4349799 asd 8218953 asd Escherichia coli O157:H7 str. TW14359 aspartate-semialdehyde dehydrogenase YP_003080189.1 4348696 R 544404 CDS YP_003080190.1 254795353 8218954 4349991..4350584 1 NC_013008.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4350584 yhgN 8218954 yhgN Escherichia coli O157:H7 str. TW14359 dITP- and XTP- hydrolase YP_003080190.1 4349991 D 544404 CDS YP_003080191.1 254795354 8218955 complement(4350630..4351832) 1 NC_013008.1 DNA processing protein 4351832 8218955 ECSP_4389 Escherichia coli O157:H7 str. TW14359 DNA processing protein YP_003080191.1 4350630 R 544404 CDS YP_003080192.1 254795355 8218957 complement(4354096..4355436) 1 NC_013008.1 low affinity gluconate transporter 4355436 gntU 8218957 gntU Escherichia coli O157:H7 str. TW14359 low affinity gluconate transporter YP_003080192.1 4354096 R 544404 CDS YP_003080193.1 254795356 8218958 complement(4355440..4355967) 1 NC_013008.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 4355967 gntK 8218958 gntK Escherichia coli O157:H7 str. TW14359 gluconate kinase 1 YP_003080193.1 4355440 R 544404 CDS YP_003080194.1 254795357 8218959 complement(4356106..4357101) 1 NC_013008.1 DNA-binding transcriptional repressor 4357101 gntR 8218959 gntR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor YP_003080194.1 4356106 R 544404 CDS YP_003080195.1 254795358 8218960 complement(4357325..4358020) 1 NC_013008.1 hypothetical protein 4358020 yhhW 8218960 yhhW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080195.1 4357325 R 544404 CDS YP_003080196.1 254795359 8218961 complement(4358143..4359180) 1 NC_013008.1 dehydrogenase 4359180 yhhX 8218961 yhhX Escherichia coli O157:H7 str. TW14359 dehydrogenase YP_003080196.1 4358143 R 544404 CDS YP_003080197.1 254795360 8218962 4359514..4360002 1 NC_013008.1 YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 4360002 yhhY 8218962 yhhY Escherichia coli O157:H7 str. TW14359 acetyltransferase YhhY YP_003080197.1 4359514 D 544404 CDS YP_003080198.1 254795361 8218963 4360213..4361124 1 NC_013008.1 hypothetical protein 4361124 8218963 ECSP_4397 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080198.1 4360213 D 544404 CDS YP_003080199.1 254795362 8218964 complement(4361073..4361489) 1 NC_013008.1 hypothetical protein 4361489 8218964 ECSP_4398 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080199.1 4361073 R 544404 CDS YP_003080200.1 254795363 8218965 complement(4361858..4363603) 1 NC_013008.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 4363603 ggt 8218965 ggt Escherichia coli O157:H7 str. TW14359 gamma-glutamyltranspeptidase YP_003080200.1 4361858 R 544404 CDS YP_003080201.1 254795364 8218966 4363723..4364163 1 NC_013008.1 hypothetical protein 4364163 yhhA 8218966 yhhA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080201.1 4363723 D 544404 CDS YP_003080202.1 254795365 8218967 complement(4364150..4364893) 1 NC_013008.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase 4364893 ugpQ 8218967 ugpQ Escherichia coli O157:H7 str. TW14359 cytoplasmic glycerophosphodiester phosphodiesterase YP_003080202.1 4364150 R 544404 CDS YP_003080203.1 254795366 8218968 complement(4364890..4365960) 1 NC_013008.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 4365960 ugpC 8218968 ugpC Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate transporter ATP-binding subunit YP_003080203.1 4364890 R 544404 CDS YP_003080204.1 254795367 8218969 complement(4365962..4366807) 1 NC_013008.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 4366807 ugpE 8218969 ugpE Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate transporter membrane protein YP_003080204.1 4365962 R 544404 CDS YP_003080205.1 254795368 8218970 complement(4366804..4367691) 1 NC_013008.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 4367691 ugpA 8218970 ugpA Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate transporter permease YP_003080205.1 4366804 R 544404 CDS YP_003080206.1 254795369 8218971 complement(4367789..4369105) 1 NC_013008.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 4369105 ugpB 8218971 ugpB Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate transporter periplasmic binding protein YP_003080206.1 4367789 R 544404 CDS YP_003080207.1 254795370 8218972 complement(4369465..4370211) 1 NC_013008.1 hypothetical protein 4370211 8218972 ECSP_4406 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080207.1 4369465 R 544404 CDS YP_003080208.1 254795371 8218973 complement(4370330..4371043) 1 NC_013008.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4371043 livF 8218973 livF Escherichia coli O157:H7 str. TW14359 leucine/isoleucine/valine transporter ATP-binding subunit YP_003080208.1 4370330 R 544404 CDS YP_003080209.1 254795372 8218974 complement(4371045..4371812) 1 NC_013008.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4371812 livG 8218974 livG Escherichia coli O157:H7 str. TW14359 leucine/isoleucine/valine transporter ATP-binding subunit YP_003080209.1 4371045 R 544404 CDS YP_003080210.1 254795373 8218975 complement(4371809..4373086) 1 NC_013008.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 4373086 livM 8218975 livM Escherichia coli O157:H7 str. TW14359 leucine/isoleucine/valine transporter permease subunit YP_003080210.1 4371809 R 544404 CDS YP_003080211.1 254795374 8218976 complement(4373083..4374009) 1 NC_013008.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 4374009 livH 8218976 livH Escherichia coli O157:H7 str. TW14359 branched-chain amino acid transporter permease subunit LivH YP_003080211.1 4373083 R 544404 CDS YP_003080212.1 254795375 8218977 complement(4374057..4375166) 1 NC_013008.1 leucine ABC transporter periplasmic-binding protein 4375166 livK 8218977 livK Escherichia coli O157:H7 str. TW14359 leucine ABC transporter periplasmic-binding protein YP_003080212.1 4374057 R 544404 CDS YP_003080213.1 254795376 8218978 complement(4375318..4375455) 1 NC_013008.1 hypothetical protein 4375455 8218978 ECSP_4412 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080213.1 4375318 R 544404 CDS YP_003080214.1 254795377 8218979 4375590..4375973 1 NC_013008.1 N-acetyltransferase 4375973 yhhK 8218979 yhhK Escherichia coli O157:H7 str. TW14359 N-acetyltransferase YP_003080214.1 4375590 D 544404 CDS YP_003080215.1 254795378 8218980 complement(4375970..4376497) 1 NC_013008.1 hypothetical protein 4376497 8218980 ECSP_4414 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080215.1 4375970 R 544404 CDS YP_003080216.1 254795379 8218981 complement(4376504..4376770) 1 NC_013008.1 hypothetical protein 4376770 8218981 ECSP_4415 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080216.1 4376504 R 544404 CDS YP_003080217.1 254795380 8218982 complement(4376920..4378023) 1 NC_013008.1 leucine/isoleucine/valine ABC transporter periplasmic-binding protein 4378023 livJ 8218982 livJ Escherichia coli O157:H7 str. TW14359 leucine/isoleucine/valine ABC transporter periplasmic-binding protein YP_003080217.1 4376920 R 544404 CDS YP_003080218.1 254795381 8218983 complement(4378294..4379148) 1 NC_013008.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 4379148 rpoH 8218983 rpoH Escherichia coli O157:H7 str. TW14359 RNA polymerase factor sigma-32 YP_003080218.1 4378294 R 544404 CDS YP_003080219.1 254795382 8218984 complement(4379393..4380451) 1 NC_013008.1 ABC transporter, membrane protein; cell division protein FtsX 4380451 ftsX 8218984 ftsX Escherichia coli O157:H7 str. TW14359 cell division protein FtsX YP_003080219.1 4379393 R 544404 CDS YP_003080220.1 254795383 8218985 complement(4380444..4381112) 1 NC_013008.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 4381112 ftsE 8218985 ftsE Escherichia coli O157:H7 str. TW14359 cell division protein FtsE YP_003080220.1 4380444 R 544404 CDS YP_003080221.1 254795384 8218986 complement(4381115..4382611) 1 NC_013008.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 4382611 ftsY 8218986 ftsY Escherichia coli O157:H7 str. TW14359 cell division protein FtsY YP_003080221.1 4381115 R 544404 CDS YP_003080222.1 254795385 8218987 4382761..4383357 1 NC_013008.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4383357 rsmD 8218987 rsmD Escherichia coli O157:H7 str. TW14359 16S rRNA m(2)G966-methyltransferase YP_003080222.1 4382761 D 544404 CDS YP_003080223.1 254795386 8218988 4383347..4383616 1 NC_013008.1 hypothetical protein 4383616 yhhL 8218988 yhhL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080223.1 4383347 D 544404 CDS YP_003080224.1 254795387 8218989 complement(4383619..4383978) 1 NC_013008.1 hypothetical protein 4383978 yhhM 8218989 yhhM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080224.1 4383619 R 544404 CDS YP_003080225.1 254795388 8218990 4384119..4384745 1 NC_013008.1 hypothetical protein 4384745 yhhN 8218990 yhhN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080225.1 4384119 D 544404 CDS YP_003080226.1 254795389 8218991 4384819..4387017 1 NC_013008.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4387017 zntA 8218991 zntA Escherichia coli O157:H7 str. TW14359 zinc/cadmium/mercury/lead-transporting ATPase YP_003080226.1 4384819 D 544404 CDS YP_003080227.1 254795390 8218992 complement(4387119..4387364) 1 NC_013008.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 4387364 sirA 8218992 sirA Escherichia coli O157:H7 str. TW14359 sulfur transfer protein SirA YP_003080227.1 4387119 R 544404 CDS YP_003080228.1 254795391 8218993 4387585..4388250 1 NC_013008.1 hypothetical protein 4388250 yhhQ 8218993 yhhQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080228.1 4387585 D 544404 CDS YP_003080229.1 254795392 8218994 4388323..4388880 1 NC_013008.1 hypothetical protein 4388880 dcrB 8218994 dcrB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080229.1 4388323 D 544404 CDS YP_003080230.1 254795393 8218995 complement(4388884..4390101) 1 NC_013008.1 major facilitator superfamily transporter 4390101 yhhS 8218995 yhhS Escherichia coli O157:H7 str. TW14359 major facilitator superfamily transporter YP_003080230.1 4388884 R 544404 CDS YP_003080231.1 254795394 8218996 4390233..4391282 1 NC_013008.1 inner membrane protein 4391282 yhhT 8218996 yhhT Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080231.1 4390233 D 544404 CDS YP_003080232.1 254795395 8218997 4391674..4392051 1 NC_013008.1 hypothetical protein 4392051 8218997 ECSP_4431 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080232.1 4391674 D 544404 CDS YP_003080233.1 254795396 8218998 4392120..4393178 1 NC_013008.1 O-methyltransferase 4393178 8218998 ECSP_4432 Escherichia coli O157:H7 str. TW14359 O-methyltransferase YP_003080233.1 4392120 D 544404 CDS YP_003080234.1 254795397 8218999 4393219..4393941 1 NC_013008.1 hypothetical protein 4393941 8218999 ECSP_4433 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080234.1 4393219 D 544404 CDS YP_003080235.1 254795398 8219000 4394091..4394759 1 NC_013008.1 phospholipid biosynthesis acyltransferase 4394759 8219000 ECSP_4434 Escherichia coli O157:H7 str. TW14359 phospholipid biosynthesis acyltransferase YP_003080235.1 4394091 D 544404 CDS YP_003080236.1 254795399 8219001 4394734..4394991 1 NC_013008.1 acyl carrier protein 4394991 8219001 ECSP_4435 Escherichia coli O157:H7 str. TW14359 acyl carrier protein YP_003080236.1 4394734 D 544404 CDS YP_003080237.1 254795400 8219002 4395003..4395254 1 NC_013008.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 4395254 8219002 ECSP_4436 Escherichia coli O157:H7 str. TW14359 acyl carrier protein YP_003080237.1 4395003 D 544404 CDS YP_003080238.1 254795401 8219003 4395259..4395840 1 NC_013008.1 hypothetical protein 4395840 8219003 ECSP_4437 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080238.1 4395259 D 544404 CDS YP_003080239.1 254795402 8219005 4397185..4397538 1 NC_013008.1 hypothetical protein 4397538 8219005 ECSP_4439 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080239.1 4397185 D 544404 CDS YP_003080240.1 254795403 8219006 4397529..4399205 1 NC_013008.1 hypothetical protein 4399205 8219006 ECSP_4440 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080240.1 4397529 D 544404 CDS YP_003080241.1 254795404 8219007 4399209..4399631 1 NC_013008.1 hypothetical protein 4399631 8219007 ECSP_4441 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080241.1 4399209 D 544404 CDS YP_003080242.1 254795405 8219008 4399628..4400233 1 NC_013008.1 hypothetical protein 4400233 8219008 ECSP_4442 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080242.1 4399628 D 544404 CDS YP_003080243.1 254795406 8219009 4400271..4402520 1 NC_013008.1 hypothetical protein 4402520 8219009 ECSP_4443 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080243.1 4400271 D 544404 CDS YP_003080244.1 254795407 8219010 4402517..4403101 1 NC_013008.1 hypothetical protein 4403101 8219010 ECSP_4444 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080244.1 4402517 D 544404 CDS YP_003080245.1 254795408 8219011 4403103..4404272 1 NC_013008.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 4404272 8219011 ECSP_4445 Escherichia coli O157:H7 str. TW14359 3-oxoacyl-ACP synthase YP_003080245.1 4403103 D 544404 CDS YP_003080246.1 254795409 8219012 4404269..4404733 1 NC_013008.1 hypothetical protein 4404733 8219012 ECSP_4446 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080246.1 4404269 D 544404 CDS YP_003080247.1 254795410 8219013 4404733..4405464 1 NC_013008.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4405464 fabG 8219013 fabG Escherichia coli O157:H7 str. TW14359 3-ketoacyl-ACP reductase YP_003080247.1 4404733 D 544404 CDS YP_003080248.1 254795411 8219014 4405461..4406690 1 NC_013008.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 4406690 8219014 ECSP_4448 Escherichia coli O157:H7 str. TW14359 3-oxoacyl-ACP synthase YP_003080248.1 4405461 D 544404 CDS YP_003080249.1 254795412 8219015 4406692..4407279 1 NC_013008.1 holo-(acyl carrier protein) synthase 2 4407279 acpT 8219015 acpT Escherichia coli O157:H7 str. TW14359 holo-(acyl carrier protein) synthase 2 YP_003080249.1 4406692 D 544404 CDS YP_003080250.1 254795413 8219016 4407390..4408964 1 NC_013008.1 nickel ABC transporter periplasmic-binding protein 4408964 nikA 8219016 nikA Escherichia coli O157:H7 str. TW14359 nickel ABC transporter periplasmic-binding protein YP_003080250.1 4407390 D 544404 CDS YP_003080251.1 254795414 8219017 4408964..4409908 1 NC_013008.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4409908 nikB 8219017 nikB Escherichia coli O157:H7 str. TW14359 nickel transporter permease NikB YP_003080251.1 4408964 D 544404 CDS YP_003080252.1 254795415 8219018 4409905..4410738 1 NC_013008.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4410738 nikC 8219018 nikC Escherichia coli O157:H7 str. TW14359 nickel transporter permease NikC YP_003080252.1 4409905 D 544404 CDS YP_003080253.1 254795416 8219019 4410738..4411502 1 NC_013008.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4411502 nikD 8219019 nikD Escherichia coli O157:H7 str. TW14359 nickel transporter ATP-binding protein NikD YP_003080253.1 4410738 D 544404 CDS YP_003080254.1 254795417 8219020 4411499..4412305 1 NC_013008.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4412305 nikE 8219020 nikE Escherichia coli O157:H7 str. TW14359 nickel transporter ATP-binding protein NikE YP_003080254.1 4411499 D 544404 CDS YP_003080255.1 254795418 8219021 4412311..4412712 1 NC_013008.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4412712 nikR 8219021 nikR Escherichia coli O157:H7 str. TW14359 nickel responsive regulator YP_003080255.1 4412311 D 544404 CDS YP_003080256.1 254795419 8219022 4412902..4413657 1 NC_013008.1 regulator 4413657 8219022 ECSP_4456 Escherichia coli O157:H7 str. TW14359 regulator YP_003080256.1 4412902 D 544404 CDS YP_003080257.1 254795420 8219023 4413682..4414155 1 NC_013008.1 phosphotransferase system enzyme subunit 4414155 8219023 ECSP_4457 Escherichia coli O157:H7 str. TW14359 phosphotransferase system enzyme subunit YP_003080257.1 4413682 D 544404 CDS YP_003080258.1 254795421 8219024 4414152..4414433 1 NC_013008.1 phosphotransferase system enzyme subunit 4414433 8219024 ECSP_4458 Escherichia coli O157:H7 str. TW14359 phosphotransferase system enzyme subunit YP_003080258.1 4414152 D 544404 CDS YP_003080259.1 254795422 8219025 4414510..4415868 1 NC_013008.1 phosphotransferase system enzyme subunit 4415868 8219025 ECSP_4459 Escherichia coli O157:H7 str. TW14359 phosphotransferase system enzyme subunit YP_003080259.1 4414510 D 544404 CDS YP_003080260.1 254795423 8219026 4415861..4417369 1 NC_013008.1 xylulose kinase 4417369 8219026 ECSP_4460 Escherichia coli O157:H7 str. TW14359 xylulose kinase YP_003080260.1 4415861 D 544404 CDS YP_003080261.1 254795424 8219027 4417359..4417628 1 NC_013008.1 phosphocarrier protein 4417628 8219027 ECSP_4461 Escherichia coli O157:H7 str. TW14359 phosphocarrier protein YP_003080261.1 4417359 D 544404 CDS YP_003080262.1 254795425 8219028 4417660..4418520 1 NC_013008.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 4418520 gatY 8219028 gatY Escherichia coli O157:H7 str. TW14359 fructose-1,6-bisphosphate aldolase YP_003080262.1 4417660 D 544404 CDS YP_003080263.1 254795426 8219029 complement(4418570..4418929) 1 NC_013008.1 hypothetical protein 4418929 8219029 ECSP_4463 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080263.1 4418570 R 544404 CDS YP_003080264.1 254795427 8219030 complement(4418926..4419201) 1 NC_013008.1 hypothetical protein 4419201 8219030 ECSP_4464 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080264.1 4418926 R 544404 CDS YP_003080265.1 254795428 8219031 complement(4419274..4420398) 1 NC_013008.1 ABC transporter membrane protein 4420398 yhhJ 8219031 yhhJ Escherichia coli O157:H7 str. TW14359 ABC transporter membrane protein YP_003080265.1 4419274 R 544404 CDS YP_003080266.1 254795429 8219032 complement(4420398..4423133) 1 NC_013008.1 fused ribosome-associated ATPase: ATP-binding protein, ATP-binding protein, membrane protein 4423133 rbbA 8219032 rbbA Escherichia coli O157:H7 str. TW14359 fused ribosome-associated ATPase: ATP-binding protein, ATP-binding protein, membrane protein YP_003080266.1 4420398 R 544404 CDS YP_003080267.1 254795430 8219033 complement(4423130..4424197) 1 NC_013008.1 HlyD family secretion protein 4424197 yhiI 8219033 yhiI Escherichia coli O157:H7 str. TW14359 HlyD family secretion protein YP_003080267.1 4423130 R 544404 CDS YP_003080268.1 254795431 8219034 complement(4424563..4426185) 1 NC_013008.1 hypothetical protein 4426185 yhiJ 8219034 yhiJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080268.1 4424563 R 544404 CDS YP_003080269.1 254795432 8219035 complement(4426447..4428057) 1 NC_013008.1 hypothetical protein 4428057 8219035 ECSP_4469 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080269.1 4426447 R 544404 CDS YP_003080270.1 254795433 8219036 4428441..4429493 1 NC_013008.1 hypothetical protein 4429493 yhiM 8219036 yhiM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080270.1 4428441 D 544404 CDS YP_003080271.1 254795434 8219037 complement(4429520..4429675) 1 NC_013008.1 hypothetical protein 4429675 8219037 ECSP_4471 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080271.1 4429520 R 544404 CDS YP_003080272.1 254795435 8219038 complement(4429811..4431013) 1 NC_013008.1 oxidoreductase 4431013 yhiN 8219038 yhiN Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003080272.1 4429811 R 544404 CDS YP_003080273.1 254795436 8219039 4431245..4432744 1 NC_013008.1 phosphate transporter, low-affinity 4432744 pitA 8219039 pitA Escherichia coli O157:H7 str. TW14359 phosphate transporter, low-affinity YP_003080273.1 4431245 D 544404 CDS YP_003080274.1 254795437 8219040 complement(4432815..4433150) 1 NC_013008.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 4433150 uspB 8219040 uspB Escherichia coli O157:H7 str. TW14359 universal stress protein UspB YP_003080274.1 4432815 R 544404 CDS YP_003080275.1 254795438 8219041 4433541..4433975 1 NC_013008.1 universal stress global response regulator 4433975 uspA 8219041 uspA Escherichia coli O157:H7 str. TW14359 universal stress global response regulator YP_003080275.1 4433541 D 544404 CDS YP_003080276.1 254795439 8219042 4434292..4435761 1 NC_013008.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4435761 yhiP 8219042 yhiP Escherichia coli O157:H7 str. TW14359 inner membrane transporter YhiP YP_003080276.1 4434292 D 544404 CDS YP_003080277.1 254795440 8219043 complement(4435810..4436562) 1 NC_013008.1 predicted SAM-dependent methyltransferase; methyltransferase 4436562 yhiQ 8219043 yhiQ Escherichia coli O157:H7 str. TW14359 methyltransferase YP_003080277.1 4435810 R 544404 CDS YP_003080278.1 254795441 8219044 complement(4436570..4438612) 1 NC_013008.1 oligopeptidase A 4438612 prlC 8219044 prlC Escherichia coli O157:H7 str. TW14359 oligopeptidase A YP_003080278.1 4436570 R 544404 CDS YP_003080279.1 254795442 8219045 4438815..4439657 1 NC_013008.1 DNA (exogenous) processing protein 4439657 yhiR 8219045 yhiR Escherichia coli O157:H7 str. TW14359 DNA (exogenous) processing protein YP_003080279.1 4438815 D 544404 CDS YP_003080280.1 254795443 8219046 4439729..4441081 1 NC_013008.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4441081 gor 8219046 gor Escherichia coli O157:H7 str. TW14359 glutathione reductase YP_003080280.1 4439729 D 544404 CDS YP_003080281.1 254795444 8219047 4441962..4442315 1 NC_013008.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 4442315 arsR 8219047 arsR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor ArsR YP_003080281.1 4441962 D 544404 CDS YP_003080282.1 254795445 8219048 4442369..4443658 1 NC_013008.1 arsenite/antimonite transporter 4443658 arsB 8219048 arsB Escherichia coli O157:H7 str. TW14359 arsenite/antimonite transporter YP_003080282.1 4442369 D 544404 CDS YP_003080283.1 254795446 8219049 4443671..4444096 1 NC_013008.1 arsenate reductase 4444096 arsC 8219049 arsC Escherichia coli O157:H7 str. TW14359 arsenate reductase YP_003080283.1 4443671 D 544404 CDS YP_003080284.1 254795447 8219050 4444208..4444315 1 NC_013008.1 hypothetical protein 4444315 8219050 ECSP_4484 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080284.1 4444208 D 544404 CDS YP_003080285.1 254795448 8219051 4444723..4445838 1 NC_013008.1 hypothetical protein 4445838 yhiS 8219051 yhiS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080285.1 4444723 D 544404 CDS YP_003080286.1 254795449 8219052 4446192..4446758 1 NC_013008.1 outer membrane lipoprotein 4446758 slp 8219052 slp Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003080286.1 4446192 D 544404 CDS YP_003080287.1 254795450 8219053 4446914..4447444 1 NC_013008.1 DNA-binding transcriptional regulator 4447444 yhiF 8219053 yhiF Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080287.1 4446914 D 544404 CDS YP_003080288.1 254795451 8219054 complement(4447505..4448533) 1 NC_013008.1 heme oxygenase 4448533 chuS 8219054 chuS Escherichia coli O157:H7 str. TW14359 heme oxygenase YP_003080288.1 4447505 R 544404 CDS YP_003080289.1 254795452 8219055 complement(4448582..4450564) 1 NC_013008.1 outer membrane heme/hemoglobin receptor 4450564 chuA 8219055 chuA Escherichia coli O157:H7 str. TW14359 outer membrane heme/hemoglobin receptor YP_003080289.1 4448582 R 544404 CDS YP_003080290.1 254795453 8219056 complement(4450840..4451139) 1 NC_013008.1 hypothetical protein 4451139 8219056 ECSP_4490 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080290.1 4450840 R 544404 CDS YP_003080291.1 254795454 8219057 4451247..4452161 1 NC_013008.1 periplasmic heme-binding protein 4452161 chuT 8219057 chuT Escherichia coli O157:H7 str. TW14359 periplasmic heme-binding protein YP_003080291.1 4451247 D 544404 CDS YP_003080292.1 254795455 8219058 4452181..4453518 1 NC_013008.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4453518 chuW 8219058 chuW Escherichia coli O157:H7 str. TW14359 coproporphyrinogen III oxidase YP_003080292.1 4452181 D 544404 CDS YP_003080293.1 254795456 8219059 4453531..4454025 1 NC_013008.1 hypothetical protein 4454025 chuX 8219059 chuX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080293.1 4453531 D 544404 CDS YP_003080294.1 254795457 8219060 4454025..4454648 1 NC_013008.1 hypothetical protein 4454648 chuY 8219060 chuY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080294.1 4454025 D 544404 CDS YP_003080295.1 254795458 8219061 4454697..4455689 1 NC_013008.1 permease of iron compound ABC transport system 4455689 chuU 8219061 chuU Escherichia coli O157:H7 str. TW14359 permease of iron compound ABC transport system YP_003080295.1 4454697 D 544404 CDS YP_003080296.1 254795459 8219062 4455686..4456456 1 NC_013008.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4456456 hmuV 8219062 hmuV Escherichia coli O157:H7 str. TW14359 hemin importer ATP-binding subunit YP_003080296.1 4455686 D 544404 CDS YP_003080297.1 254795460 8219063 complement(4456508..4457155) 1 NC_013008.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 4457155 yhiD 8219063 yhiD Escherichia coli O157:H7 str. TW14359 Mg(2+) transport ATPase YP_003080297.1 4456508 R 544404 CDS YP_003080298.1 254795461 8219064 complement(4457219..4457557) 1 NC_013008.1 acid-resistance protein 4457557 hdeB 8219064 hdeB Escherichia coli O157:H7 str. TW14359 acid-resistance protein YP_003080298.1 4457219 R 544404 CDS YP_003080299.1 254795462 8219065 complement(4457661..4457993) 1 NC_013008.1 inactive form; acid-resistance protein 4457993 hdeA 8219065 hdeA Escherichia coli O157:H7 str. TW14359 acid-resistance protein YP_003080299.1 4457661 R 544404 CDS YP_003080300.1 254795463 8219066 4458248..4458820 1 NC_013008.1 acid-resistance membrane protein 4458820 hdeD 8219066 hdeD Escherichia coli O157:H7 str. TW14359 acid-resistance membrane protein YP_003080300.1 4458248 D 544404 CDS YP_003080301.1 254795464 8219067 4459619..4460146 1 NC_013008.1 acid-induced positive regulator of glutamate-dependent acid resistance 4460146 gadE 8219067 gadE Escherichia coli O157:H7 str. TW14359 acid-induced positive regulator of glutamate-dependent acid resistance YP_003080301.1 4459619 D 544404 CDS YP_003080302.1 254795465 8219068 4460485..4461642 1 NC_013008.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4461642 mdtE 8219068 mdtE Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein MdtE YP_003080302.1 4460485 D 544404 CDS YP_003080303.1 254795466 8219069 4461667..4464780 1 NC_013008.1 multidrug transporter, RpoS-dependent 4464780 mdtF 8219069 mdtF Escherichia coli O157:H7 str. TW14359 multidrug transporter, RpoS-dependent YP_003080303.1 4461667 D 544404 CDS YP_003080304.1 254795467 8219070 complement(4465143..4465871) 1 NC_013008.1 DNA-binding transcriptional activator 4465871 gadW 8219070 gadW Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator YP_003080304.1 4465143 R 544404 CDS YP_003080305.1 254795468 8219071 complement(4465944..4466051) 1 NC_013008.1 hypothetical protein 4466051 8219071 ECSP_4505 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080305.1 4465944 R 544404 CDS YP_003080306.1 254795469 8219072 complement(4466239..4467063) 1 NC_013008.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 4467063 gadX 8219072 gadX Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator GadX YP_003080306.1 4466239 R 544404 CDS YP_003080307.1 254795470 8219073 complement(4467434..4468834) 1 NC_013008.1 glutamate decarboxylase A, PLP-dependent 4468834 gadA 8219073 gadA Escherichia coli O157:H7 str. TW14359 glutamate decarboxylase A, PLP-dependent YP_003080307.1 4467434 R 544404 CDS YP_003080308.1 254795471 8219074 complement(4469045..4470442) 1 NC_013008.1 cytochrome C peroxidase 4470442 yhjA 8219074 yhjA Escherichia coli O157:H7 str. TW14359 cytochrome C peroxidase YP_003080308.1 4469045 R 544404 CDS YP_003080309.1 254795472 8219075 4470847..4472496 1 NC_013008.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4472496 treF 8219075 treF Escherichia coli O157:H7 str. TW14359 trehalase YP_003080309.1 4470847 D 544404 CDS YP_003080310.1 254795473 8219076 complement(4472547..4473149) 1 NC_013008.1 DNA-binding response regulator in two-component regulatory system 4473149 yhjB 8219076 yhjB Escherichia coli O157:H7 str. TW14359 DNA-binding response regulator in two-component regulatory system YP_003080310.1 4472547 R 544404 CDS YP_003080311.1 254795474 8219077 4473669..4474568 1 NC_013008.1 DNA-binding transcriptional regulator 4474568 yhjC 8219077 yhjC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080311.1 4473669 D 544404 CDS YP_003080312.1 254795475 8219078 4474617..4475630 1 NC_013008.1 hypothetical protein 4475630 yhjD 8219078 yhjD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080312.1 4474617 D 544404 CDS YP_003080313.1 254795476 8219079 4476042..4477364 1 NC_013008.1 transporter 4477364 yhjE 8219079 yhjE Escherichia coli O157:H7 str. TW14359 transporter YP_003080313.1 4476042 D 544404 CDS YP_003080314.1 254795477 8219080 complement(4477546..4479606) 1 NC_013008.1 outer membrane biogenesis protein 4479606 yhjG 8219080 yhjG Escherichia coli O157:H7 str. TW14359 outer membrane biogenesis protein YP_003080314.1 4477546 R 544404 CDS YP_003080315.1 254795478 8219081 complement(4479676..4480443) 1 NC_013008.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 4480443 yhjH 8219081 yhjH Escherichia coli O157:H7 str. TW14359 EAL domain-containing protein YP_003080315.1 4479676 R 544404 CDS YP_003080316.1 254795479 8219082 4480675..4481604 1 NC_013008.1 ketodeoxygluconokinase 4481604 kdgK 8219082 kdgK Escherichia coli O157:H7 str. TW14359 ketodeoxygluconokinase YP_003080316.1 4480675 D 544404 CDS YP_003080317.1 254795480 8219083 complement(4481700..4483196) 1 NC_013008.1 zinc-dependent peptidase 4483196 yhjJ 8219083 yhjJ Escherichia coli O157:H7 str. TW14359 zinc-dependent peptidase YP_003080317.1 4481700 R 544404 CDS YP_003080318.1 254795481 8219084 complement(4483417..4484703) 1 NC_013008.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4484703 dctA 8219084 dctA Escherichia coli O157:H7 str. TW14359 C4-dicarboxylate transporter DctA YP_003080318.1 4483417 R 544404 CDS YP_003080319.1 254795482 8219085 complement(4484886..4486874) 1 NC_013008.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase 4486874 yhjK 8219085 yhjK Escherichia coli O157:H7 str. TW14359 phosphodiesterase YP_003080319.1 4484886 R 544404 CDS YP_003080320.1 254795483 8219086 complement(4486956..4489964) 1 NC_013008.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 4489964 bcsC 8219086 bcsC Escherichia coli O157:H7 str. TW14359 cellulose synthase subunit BcsC YP_003080320.1 4486956 R 544404 CDS YP_003080321.1 254795484 8219087 complement(4490411..4491517) 1 NC_013008.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 4491517 bcsZ 8219087 bcsZ Escherichia coli O157:H7 str. TW14359 endo-1,4-D-glucanase YP_003080321.1 4490411 R 544404 CDS YP_003080322.1 254795485 8219088 complement(4491524..4493899) 1 NC_013008.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 4493899 bcsB 8219088 bcsB Escherichia coli O157:H7 str. TW14359 cellulose synthase regulator protein YP_003080322.1 4491524 R 544404 CDS YP_003080323.1 254795486 8219089 complement(4493910..4496528) 1 NC_013008.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 4496528 bcsA 8219089 bcsA Escherichia coli O157:H7 str. TW14359 cellulose synthase catalytic subunit YP_003080323.1 4493910 R 544404 CDS YP_003080324.1 254795487 8219090 complement(4497080..4497277) 1 NC_013008.1 hypothetical protein 4497277 8219090 ECSP_4524 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080324.1 4497080 R 544404 CDS YP_003080325.1 254795488 8219091 complement(4497289..4497477) 1 NC_013008.1 hypothetical protein 4497477 yhjR 8219091 yhjR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080325.1 4497289 R 544404 CDS YP_003080326.1 254795489 8219092 4497750..4499321 1 NC_013008.1 hypothetical protein 4499321 bcsE 8219092 bcsE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080326.1 4497750 D 544404 CDS YP_003080327.1 254795490 8219093 4499318..4499509 1 NC_013008.1 hypothetical protein 4499509 bcsF 8219093 bcsF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080327.1 4499318 D 544404 CDS YP_003080328.1 254795491 8219094 4499506..4501185 1 NC_013008.1 inner membrane protein 4501185 bcsG 8219094 bcsG Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080328.1 4499506 D 544404 CDS YP_003080329.1 254795492 8219095 complement(4501272..4501379) 1 NC_013008.1 toxic polypeptide, small 4501379 ldrD 8219095 ldrD Escherichia coli O157:H7 str. TW14359 toxic polypeptide, small YP_003080329.1 4501272 R 544404 CDS YP_003080330.1 254795493 8219096 4501855..4503126 1 NC_013008.1 transporter 4503126 yhjV 8219096 yhjV Escherichia coli O157:H7 str. TW14359 transporter YP_003080330.1 4501855 D 544404 CDS YP_003080331.1 254795494 8219097 complement(4503156..4504160) 1 NC_013008.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4504160 dppF 8219097 dppF Escherichia coli O157:H7 str. TW14359 dipeptide transporter ATP-binding subunit YP_003080331.1 4503156 R 544404 CDS YP_003080332.1 254795495 8219098 complement(4504157..4505140) 1 NC_013008.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4505140 dppD 8219098 dppD Escherichia coli O157:H7 str. TW14359 dipeptide transporter ATP-binding subunit YP_003080332.1 4504157 R 544404 CDS YP_003080333.1 254795496 8219099 complement(4505151..4506053) 1 NC_013008.1 dipeptide transporter 4506053 dppC 8219099 dppC Escherichia coli O157:H7 str. TW14359 dipeptide transporter YP_003080333.1 4505151 R 544404 CDS YP_003080334.1 254795497 8219100 complement(4506063..4507082) 1 NC_013008.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4507082 dppB 8219100 dppB Escherichia coli O157:H7 str. TW14359 dipeptide transporter permease DppB YP_003080334.1 4506063 R 544404 CDS YP_003080335.1 254795498 8219101 complement(4507233..4508840) 1 NC_013008.1 dipeptide ABC transporter periplasmic-binding protein 4508840 dppA 8219101 dppA Escherichia coli O157:H7 str. TW14359 dipeptide ABC transporter periplasmic-binding protein YP_003080335.1 4507233 R 544404 CDS YP_003080336.1 254795499 8219103 complement(4509753..4511444) 1 NC_013008.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4511444 eptB 8219103 eptB Escherichia coli O157:H7 str. TW14359 phosphoethanolamine transferase YP_003080336.1 4509753 R 544404 CDS YP_003080337.1 254795500 8219104 complement(4511699..4512229) 1 NC_013008.1 fimbrial subunit 4512229 lpfE 8219104 lpfE Escherichia coli O157:H7 str. TW14359 fimbrial subunit YP_003080337.1 4511699 R 544404 CDS YP_003080338.1 254795501 8219105 complement(4512234..4513289) 1 NC_013008.1 fimbrial protein 4513289 lpfD 8219105 lpfD Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003080338.1 4512234 R 544404 CDS YP_003080339.1 254795502 8219107 complement(4515906..4516592) 1 NC_013008.1 fimbrial chaperone 4516592 lpfB 8219107 lpfB Escherichia coli O157:H7 str. TW14359 fimbrial chaperone YP_003080339.1 4515906 R 544404 CDS YP_003080340.1 254795503 8219108 complement(4516657..4517193) 1 NC_013008.1 major fimbrial subunit 4517193 lpfA 8219108 lpfA Escherichia coli O157:H7 str. TW14359 major fimbrial subunit YP_003080340.1 4516657 R 544404 CDS YP_003080341.1 254795504 8219109 complement(4517525..4518727) 1 NC_013008.1 transporter 4518727 yhjX 8219109 yhjX Escherichia coli O157:H7 str. TW14359 transporter YP_003080341.1 4517525 R 544404 CDS YP_003080342.1 254795505 8219110 complement(4518956..4519654) 1 NC_013008.1 hypothetical protein 4519654 yhjY 8219110 yhjY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080342.1 4518956 R 544404 CDS YP_003080343.1 254795506 8219111 4519812..4520375 1 NC_013008.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 4520375 tag 8219111 tag Escherichia coli O157:H7 str. TW14359 3-methyl-adenine DNA glycosylase I YP_003080343.1 4519812 D 544404 CDS YP_003080344.1 254795507 8219112 4520372..4520812 1 NC_013008.1 hypothetical protein 4520812 yiaC 8219112 yiaC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080344.1 4520372 D 544404 CDS YP_003080345.1 254795508 8219113 complement(4520781..4523114) 1 NC_013008.1 biotin sulfoxide reductase 4523114 bisC 8219113 bisC Escherichia coli O157:H7 str. TW14359 biotin sulfoxide reductase YP_003080345.1 4520781 R 544404 CDS YP_003080346.1 254795509 8219114 4523267..4523926 1 NC_013008.1 outer membrane lipoprotein 4523926 yiaD 8219114 yiaD Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein YP_003080346.1 4523267 D 544404 CDS YP_003080347.1 254795510 8219115 4524030..4525004 1 NC_013008.1 2-keto-D-gluconate reductase 4525004 ghrB 8219115 ghrB Escherichia coli O157:H7 str. TW14359 2-keto-D-gluconate reductase YP_003080347.1 4524030 D 544404 CDS YP_003080348.1 254795511 8219116 complement(4525054..4525764) 1 NC_013008.1 hypothetical protein 4525764 yiaF 8219116 yiaF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080348.1 4525054 R 544404 CDS YP_003080349.1 254795512 8219117 4526198..4526488 1 NC_013008.1 transcriptional regulator 4526488 yiaG 8219117 yiaG Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003080349.1 4526198 D 544404 CDS YP_003080350.1 254795513 8219118 4526769..4526981 1 NC_013008.1 major cold shock protein 4526981 cspA 8219118 cspA Escherichia coli O157:H7 str. TW14359 major cold shock protein YP_003080350.1 4526769 D 544404 CDS YP_003080351.1 254795514 8219119 complement(4527169..4527321) 1 NC_013008.1 small toxic polypeptide 4527321 hokA 8219119 hokA Escherichia coli O157:H7 str. TW14359 small toxic polypeptide YP_003080351.1 4527169 R 544404 CDS YP_003080352.1 254795515 8219120 complement(4527644..4529713) 1 NC_013008.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4529713 glyS 8219120 glyS Escherichia coli O157:H7 str. TW14359 glycyl-tRNA synthetase subunit beta YP_003080352.1 4527644 R 544404 CDS YP_003080353.1 254795516 8219121 complement(4529723..4530634) 1 NC_013008.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4530634 glyQ 8219121 glyQ Escherichia coli O157:H7 str. TW14359 glycyl-tRNA synthetase subunit alpha YP_003080353.1 4529723 R 544404 CDS YP_003080354.1 254795517 8219122 complement(4530729..4531028) 1 NC_013008.1 hypothetical protein 4531028 ysaB 8219122 ysaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080354.1 4530729 R 544404 CDS YP_003080355.1 254795518 8219123 4531203..4532198 1 NC_013008.1 hypothetical protein 4532198 yiaH 8219123 yiaH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080355.1 4531203 D 544404 CDS YP_003080356.1 254795519 8219124 complement(4532240..4532677) 1 NC_013008.1 hypothetical protein 4532677 yiaA 8219124 yiaA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080356.1 4532240 R 544404 CDS YP_003080357.1 254795520 8219125 complement(4532723..4533064) 1 NC_013008.1 hypothetical protein 4533064 yiaB 8219125 yiaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080357.1 4532723 R 544404 CDS YP_003080358.1 254795521 8219126 complement(4533233..4534687) 1 NC_013008.1 xylulokinase 4534687 xylB 8219126 xylB Escherichia coli O157:H7 str. TW14359 xylulokinase YP_003080358.1 4533233 R 544404 CDS YP_003080359.1 254795522 8219127 complement(4534759..4536081) 1 NC_013008.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4536081 xylA 8219127 xylA Escherichia coli O157:H7 str. TW14359 xylose isomerase YP_003080359.1 4534759 R 544404 CDS YP_003080360.1 254795523 8219128 4536447..4537439 1 NC_013008.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4537439 xylF 8219128 xylF Escherichia coli O157:H7 str. TW14359 D-xylose transporter subunit XylF YP_003080360.1 4536447 D 544404 CDS YP_003080361.1 254795524 8219129 4537517..4539058 1 NC_013008.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4539058 xylG 8219129 xylG Escherichia coli O157:H7 str. TW14359 xylose transporter ATP-binding subunit YP_003080361.1 4537517 D 544404 CDS YP_003080362.1 254795525 8219130 4539036..4540217 1 NC_013008.1 D-xylose ABC transporter membrane protein 4540217 xylH 8219130 xylH Escherichia coli O157:H7 str. TW14359 D-xylose ABC transporter membrane protein YP_003080362.1 4539036 D 544404 CDS YP_003080363.1 254795526 8219131 4540295..4541473 1 NC_013008.1 DNA-binding transcriptional activator, xylose-binding 4541473 xylR 8219131 xylR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator, xylose-binding YP_003080363.1 4540295 D 544404 CDS YP_003080364.1 254795527 8219132 complement(4541581..4542405) 1 NC_013008.1 hypothetical protein 4542405 bax 8219132 bax Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080364.1 4541581 R 544404 CDS YP_003080365.1 254795528 8219133 4542725..4544755 1 NC_013008.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4544755 malS 8219133 malS Escherichia coli O157:H7 str. TW14359 periplasmic alpha-amylase YP_003080365.1 4542725 D 544404 CDS YP_003080366.1 254795529 8219134 4544933..4546186 1 NC_013008.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4546186 avtA 8219134 avtA Escherichia coli O157:H7 str. TW14359 valine--pyruvate transaminase YP_003080366.1 4544933 D 544404 CDS YP_003080367.1 254795530 8219135 complement(4546338..4546811) 1 NC_013008.1 hydrogenase, 4Fe-4S ferredoxin-type component 4546811 ysaA 8219135 ysaA Escherichia coli O157:H7 str. TW14359 hydrogenase, 4Fe-4S ferredoxin-type component YP_003080367.1 4546338 R 544404 CDS YP_003080368.1 254795531 8219136 4546362..4546706 1 NC_013008.1 hypothetical protein 4546706 8219136 ECSP_4570 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080368.1 4546362 D 544404 CDS YP_003080369.1 254795532 8219137 complement(4547055..4547870) 1 NC_013008.1 regulatory protein 4547870 8219137 ECSP_4571 Escherichia coli O157:H7 str. TW14359 regulatory protein YP_003080369.1 4547055 R 544404 CDS YP_003080370.1 254795533 8219138 4548096..4549496 1 NC_013008.1 permease 4549496 8219138 ECSP_4572 Escherichia coli O157:H7 str. TW14359 permease YP_003080370.1 4548096 D 544404 CDS YP_003080371.1 254795534 8219139 4549507..4551477 1 NC_013008.1 hypothetical protein 4551477 8219139 ECSP_4573 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080371.1 4549507 D 544404 CDS YP_003080372.1 254795535 8219140 complement(4551607..4552347) 1 NC_013008.1 hypothetical protein 4552347 yiaT 8219140 yiaT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080372.1 4551607 R 544404 CDS YP_003080373.1 254795536 8219141 4552471..4553445 1 NC_013008.1 DNA-binding transcriptional regulator 4553445 yiaU 8219141 yiaU Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080373.1 4552471 D 544404 CDS YP_003080374.1 254795537 8219142 complement(4553442..4554578) 1 NC_013008.1 membrane fusion protein (MFP) component of efflux pump, signal anchor 4554578 yiaV 8219142 yiaV Escherichia coli O157:H7 str. TW14359 membrane fusion protein (MFP) component of efflux pump, signal anchor YP_003080374.1 4553442 R 544404 CDS YP_003080375.1 254795538 8219143 complement(4554584..4554907) 1 NC_013008.1 hypothetical protein 4554907 yiaW 8219143 yiaW Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080375.1 4554584 R 544404 CDS YP_003080376.1 254795539 8219144 4554950..4555069 1 NC_013008.1 hypothetical protein 4555069 8219144 ECSP_4578 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080376.1 4554950 D 544404 CDS YP_003080377.1 254795540 8219145 4555069..4555233 1 NC_013008.1 hypothetical protein 4555233 8219145 ECSP_4579 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080377.1 4555069 D 544404 CDS YP_003080378.1 254795541 8219146 complement(4555452..4556990) 1 NC_013008.1 aldehyde dehydrogenase 4556990 aldB 8219146 aldB Escherichia coli O157:H7 str. TW14359 aldehyde dehydrogenase YP_003080378.1 4555452 R 544404 CDS YP_003080379.1 254795542 8219147 complement(4557098..4558393) 1 NC_013008.1 hypothetical protein 4558393 8219147 ECSP_4581 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080379.1 4557098 R 544404 CDS YP_003080380.1 254795543 8219148 complement(4558523..4559674) 1 NC_013008.1 alcohol dehydrogenase 4559674 yiaY 8219148 yiaY Escherichia coli O157:H7 str. TW14359 alcohol dehydrogenase YP_003080380.1 4558523 R 544404 CDS YP_003080381.1 254795544 8219149 complement(4559863..4561707) 1 NC_013008.1 selenocysteinyl-tRNA-specific translation factor 4561707 selB 8219149 selB Escherichia coli O157:H7 str. TW14359 selenocysteinyl-tRNA-specific translation factor YP_003080381.1 4559863 R 544404 CDS YP_003080382.1 254795545 8219150 complement(4561704..4563095) 1 NC_013008.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4563095 selA 8219150 selA Escherichia coli O157:H7 str. TW14359 selenocysteine synthase YP_003080382.1 4561704 R 544404 CDS YP_003080383.1 254795546 8219151 complement(4563193..4563801) 1 NC_013008.1 glutathione S-transferase 4563801 yibF 8219151 yibF Escherichia coli O157:H7 str. TW14359 glutathione S-transferase YP_003080383.1 4563193 R 544404 CDS YP_003080384.1 254795547 8219152 4567315..4568259 1 NC_013008.1 Rhs-family protein 4568259 yibJ 8219152 yibJ Escherichia coli O157:H7 str. TW14359 Rhs-family protein YP_003080384.1 4567315 D 544404 CDS YP_003080385.1 254795548 8219153 4568271..4568732 1 NC_013008.1 hypothetical protein 4568732 yibG 8219153 yibG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080385.1 4568271 D 544404 CDS YP_003080386.1 254795549 8219154 4568953..4569072 1 NC_013008.1 hypothetical protein 4569072 8219154 ECSP_4588 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080386.1 4568953 D 544404 CDS YP_003080387.1 254795550 8219155 4569439..4569876 1 NC_013008.1 hypothetical protein 4569876 8219155 ECSP_4589 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080387.1 4569439 D 544404 CDS YP_003080388.1 254795551 8219156 complement(4570335..4571471) 1 NC_013008.1 hypothetical protein 4571471 yibH 8219156 yibH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080388.1 4570335 R 544404 CDS YP_003080389.1 254795552 8219157 complement(4571474..4571836) 1 NC_013008.1 inner membrane protein 4571836 yibI 8219157 yibI Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080389.1 4571474 R 544404 CDS YP_003080390.1 254795553 8219158 4572373..4574286 1 NC_013008.1 PTS system mannitol-specific transporter subunit IIABC 4574286 mtlA 8219158 mtlA Escherichia coli O157:H7 str. TW14359 PTS system mannitol-specific transporter subunit IIABC YP_003080390.1 4572373 D 544404 CDS YP_003080391.1 254795554 8219159 4574381..4575529 1 NC_013008.1 mannitol-1-phosphate 5-dehydrogenase 4575529 mtlD 8219159 mtlD Escherichia coli O157:H7 str. TW14359 mannitol-1-phosphate 5-dehydrogenase YP_003080391.1 4574381 D 544404 CDS YP_003080392.1 254795555 8219160 4575529..4576116 1 NC_013008.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4576116 mtlR 8219160 mtlR Escherichia coli O157:H7 str. TW14359 mannitol repressor protein YP_003080392.1 4575529 D 544404 CDS YP_003080393.1 254795556 8219161 complement(4576128..4576337) 1 NC_013008.1 hypothetical protein 4576337 yibT 8219161 yibT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080393.1 4576128 R 544404 CDS YP_003080394.1 254795557 8219162 4576622..4576984 1 NC_013008.1 hypothetical protein 4576984 yibL 8219162 yibL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080394.1 4576622 D 544404 CDS YP_003080395.1 254795558 8219163 complement(4577298..4577456) 1 NC_013008.1 hypothetical protein 4577456 8219163 ECSP_4597 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080395.1 4577298 R 544404 CDS YP_003080396.1 254795559 8219164 4577629..4578210 1 NC_013008.1 hypothetical protein 4578210 8219164 ECSP_4598 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080396.1 4577629 D 544404 CDS YP_003080397.1 254795560 8219165 4578254..4583020 1 NC_013008.1 adhesin 4583020 8219165 ECSP_4599 Escherichia coli O157:H7 str. TW14359 adhesin YP_003080397.1 4578254 D 544404 CDS YP_003080398.1 254795561 8219166 4583388..4585043 1 NC_013008.1 L-lactate permease 4585043 lldP 8219166 lldP Escherichia coli O157:H7 str. TW14359 L-lactate permease YP_003080398.1 4583388 D 544404 CDS YP_003080399.1 254795562 8219167 4585043..4585819 1 NC_013008.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4585819 lldR 8219167 lldR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor LldR YP_003080399.1 4585043 D 544404 CDS YP_003080400.1 254795563 8219168 4585816..4587006 1 NC_013008.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4587006 lldD 8219168 lldD Escherichia coli O157:H7 str. TW14359 L-lactate dehydrogenase YP_003080400.1 4585816 D 544404 CDS YP_003080401.1 254795564 8219169 4587192..4587665 1 NC_013008.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4587665 yibK 8219169 yibK Escherichia coli O157:H7 str. TW14359 tRNA/rRNA methyltransferase YibK YP_003080401.1 4587192 D 544404 CDS YP_003080402.1 254795565 8219170 complement(4587718..4588539) 1 NC_013008.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4588539 cysE 8219170 cysE Escherichia coli O157:H7 str. TW14359 serine acetyltransferase YP_003080402.1 4587718 R 544404 CDS YP_003080403.1 254795566 8219171 complement(4588619..4589638) 1 NC_013008.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4589638 gpsA 8219171 gpsA Escherichia coli O157:H7 str. TW14359 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_003080403.1 4588619 R 544404 CDS YP_003080404.1 254795567 8219172 complement(4589638..4590105) 1 NC_013008.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4590105 secB 8219172 secB Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecB YP_003080404.1 4589638 R 544404 CDS YP_003080405.1 254795568 8219173 complement(4590168..4590419) 1 NC_013008.1 glutaredoxin 3 4590419 grxC 8219173 grxC Escherichia coli O157:H7 str. TW14359 glutaredoxin 3 YP_003080405.1 4590168 R 544404 CDS YP_003080406.1 254795569 8219174 complement(4590561..4590992) 1 NC_013008.1 rhodanese-related sulfurtransferase 4590992 yibN 8219174 yibN Escherichia coli O157:H7 str. TW14359 rhodanese-related sulfurtransferase YP_003080406.1 4590561 R 544404 CDS YP_003080407.1 254795570 8219175 4591237..4592781 1 NC_013008.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4592781 gpmI 8219175 gpmI Escherichia coli O157:H7 str. TW14359 phosphoglyceromutase YP_003080407.1 4591237 D 544404 CDS YP_003080408.1 254795571 8219176 4592815..4594074 1 NC_013008.1 hypothetical protein 4594074 envC 8219176 envC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080408.1 4592815 D 544404 CDS YP_003080409.1 254795572 8219177 4594078..4595037 1 NC_013008.1 polysaccharide deacetylase 4595037 yibQ 8219177 yibQ Escherichia coli O157:H7 str. TW14359 polysaccharide deacetylase YP_003080409.1 4594078 D 544404 CDS YP_003080410.1 254795573 8219178 complement(4595043..4596059) 1 NC_013008.1 glycosyl transferase 4596059 yibD 8219178 yibD Escherichia coli O157:H7 str. TW14359 glycosyl transferase YP_003080410.1 4595043 R 544404 CDS YP_003080411.1 254795574 8219179 complement(4596298..4597323) 1 NC_013008.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4597323 tdh 8219179 tdh Escherichia coli O157:H7 str. TW14359 L-threonine 3-dehydrogenase YP_003080411.1 4596298 R 544404 CDS YP_003080412.1 254795575 8219180 complement(4597333..4598529) 1 NC_013008.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 4598529 kbl 8219180 kbl Escherichia coli O157:H7 str. TW14359 2-amino-3-ketobutyrate CoA ligase YP_003080412.1 4597333 R 544404 CDS YP_003080413.1 254795576 8219181 complement(4598804..4599661) 1 NC_013008.1 hypothetical protein 4599661 htrL 8219181 htrL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080413.1 4598804 R 544404 CDS YP_003080414.1 254795577 8219182 4599965..4600897 1 NC_013008.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4600897 rfaD 8219182 rfaD Escherichia coli O157:H7 str. TW14359 ADP-L-glycero-D-manno-heptose-6-epimerase YP_003080414.1 4599965 D 544404 CDS YP_003080415.1 254795578 8219183 4600907..4601953 1 NC_013008.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4601953 rfaF 8219183 rfaF Escherichia coli O157:H7 str. TW14359 ADP-heptose:LPS heptosyltransferase II YP_003080415.1 4600907 D 544404 CDS YP_003080416.1 254795579 8219184 4601957..4602949 1 NC_013008.1 ADP-heptose:LPS heptosyl transferase I 4602949 rfaC 8219184 rfaC Escherichia coli O157:H7 str. TW14359 ADP-heptose:LPS heptosyl transferase I YP_003080416.1 4601957 D 544404 CDS YP_003080417.1 254795580 8219185 4602946..4604154 1 NC_013008.1 LPS biosynthesis enzyme 4604154 waaL 8219185 waaL Escherichia coli O157:H7 str. TW14359 LPS biosynthesis enzyme YP_003080417.1 4602946 D 544404 CDS YP_003080418.1 254795581 8219186 complement(4604190..4605332) 1 NC_013008.1 UDP-glucose:(glucosyl) LPS alpha-1,2-glucosyltransferase 4605332 waaD 8219186 waaD Escherichia coli O157:H7 str. TW14359 UDP-glucose:(glucosyl) LPS alpha-1,2-glucosyltransferase YP_003080418.1 4604190 R 544404 CDS YP_003080419.1 254795582 8219187 complement(4605341..4606354) 1 NC_013008.1 UDP-glucose:(galactosyl) LPS alpha-1,2-glucosyltransferase 4606354 waaJ 8219187 waaJ Escherichia coli O157:H7 str. TW14359 UDP-glucose:(galactosyl) LPS alpha-1,2-glucosyltransferase YP_003080419.1 4605341 R 544404 CDS YP_003080420.1 254795583 8219188 complement(4606379..4607086) 1 NC_013008.1 lipopolysaccharide core biosynthesis protein 4607086 waaY 8219188 waaY Escherichia coli O157:H7 str. TW14359 lipopolysaccharide core biosynthesis protein YP_003080420.1 4606379 R 544404 CDS YP_003080421.1 254795584 8219189 complement(4607112..4608119) 1 NC_013008.1 LPS biosynthesis enzyme 4608119 waaI 8219189 waaI Escherichia coli O157:H7 str. TW14359 LPS biosynthesis enzyme YP_003080421.1 4607112 R 544404 CDS YP_003080422.1 254795585 8219190 complement(4608162..4608959) 1 NC_013008.1 kinase that phosphorylates core heptose of lipopolysaccharide 4608959 waaP 8219190 waaP Escherichia coli O157:H7 str. TW14359 kinase that phosphorylates core heptose of lipopolysaccharide YP_003080422.1 4608162 R 544404 CDS YP_003080423.1 254795586 8219191 complement(4608952..4610076) 1 NC_013008.1 glucosyltransferase I 4610076 rfaG 8219191 rfaG Escherichia coli O157:H7 str. TW14359 glucosyltransferase I YP_003080423.1 4608952 R 544404 CDS YP_003080424.1 254795587 8219192 complement(4610073..4611095) 1 NC_013008.1 lipopolysaccharide core biosynthesis protein 4611095 8219192 ECSP_4626 Escherichia coli O157:H7 str. TW14359 lipopolysaccharide core biosynthesis protein YP_003080424.1 4610073 R 544404 CDS YP_003080425.1 254795588 8219193 4611544..4612821 1 NC_013008.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4612821 kdtA 8219193 kdtA Escherichia coli O157:H7 str. TW14359 3-deoxy-D-manno-octulosonic-acid transferase YP_003080425.1 4611544 D 544404 CDS YP_003080426.1 254795589 8219194 4612829..4613308 1 NC_013008.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4613308 coaD 8219194 coaD Escherichia coli O157:H7 str. TW14359 phosphopantetheine adenylyltransferase YP_003080426.1 4612829 D 544404 CDS YP_003080427.1 254795590 8219195 complement(4613347..4614156) 1 NC_013008.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4614156 mutM 8219195 mutM Escherichia coli O157:H7 str. TW14359 formamidopyrimidine-DNA glycosylase YP_003080427.1 4613347 R 544404 CDS YP_003080428.1 254795591 8219196 complement(4614254..4614421) 1 NC_013008.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4614421 rpmG 8219196 rpmG Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L33 YP_003080428.1 4614254 R 544404 CDS YP_003080429.1 254795592 8219197 complement(4614442..4614678) 1 NC_013008.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4614678 rpmB 8219197 rpmB Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L28 YP_003080429.1 4614442 R 544404 CDS YP_003080430.1 254795593 8219198 complement(4614895..4615563) 1 NC_013008.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4615563 radC 8219198 radC Escherichia coli O157:H7 str. TW14359 DNA repair protein RadC YP_003080430.1 4614895 R 544404 CDS YP_003080431.1 254795594 8219199 4615735..4616955 1 NC_013008.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4616955 dfp 8219199 dfp Escherichia coli O157:H7 str. TW14359 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_003080431.1 4615735 D 544404 CDS YP_003080432.1 254795595 8219200 4616936..4617391 1 NC_013008.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4617391 dut 8219200 dut Escherichia coli O157:H7 str. TW14359 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_003080432.1 4616936 D 544404 CDS YP_003080433.1 254795596 8219201 4617498..4618094 1 NC_013008.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4618094 slmA 8219201 slmA Escherichia coli O157:H7 str. TW14359 nucleoid occlusion protein YP_003080433.1 4617498 D 544404 CDS YP_003080434.1 254795597 8219202 complement(4618131..4618772) 1 NC_013008.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4618772 pyrE 8219202 pyrE Escherichia coli O157:H7 str. TW14359 orotate phosphoribosyltransferase YP_003080434.1 4618131 R 544404 CDS YP_003080435.1 254795598 8219203 complement(4618838..4619554) 1 NC_013008.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4619554 rph 8219203 rph Escherichia coli O157:H7 str. TW14359 ribonuclease PH YP_003080435.1 4618838 R 544404 CDS YP_003080436.1 254795599 8219204 4619681..4620544 1 NC_013008.1 hypothetical protein 4620544 yicC 8219204 yicC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080436.1 4619681 D 544404 CDS YP_003080437.1 254795600 8219205 4620765..4621589 1 NC_013008.1 DNA-damage-inducible protein D 4621589 dinD 8219205 dinD Escherichia coli O157:H7 str. TW14359 DNA-damage-inducible protein D YP_003080437.1 4620765 D 544404 CDS YP_003080438.1 254795601 8219206 4621881..4622498 1 NC_013008.1 hypothetical protein 4622498 yicG 8219206 yicG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080438.1 4621881 D 544404 CDS YP_003080439.1 254795602 8219207 complement(4622495..4624177) 1 NC_013008.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4624177 ligB 8219207 ligB Escherichia coli O157:H7 str. TW14359 NAD-dependent DNA ligase LigB YP_003080439.1 4622495 R 544404 CDS YP_003080440.1 254795603 8219208 4624435..4625058 1 NC_013008.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4625058 gmk 8219208 gmk Escherichia coli O157:H7 str. TW14359 guanylate kinase YP_003080440.1 4624435 D 544404 CDS YP_003080441.1 254795604 8219209 4625113..4625388 1 NC_013008.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4625388 rpoZ 8219209 rpoZ Escherichia coli O157:H7 str. TW14359 DNA-directed RNA polymerase subunit omega YP_003080441.1 4625113 D 544404 CDS YP_003080442.1 254795605 8219210 4625407..4627515 1 NC_013008.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4627515 spoT 8219210 spoT Escherichia coli O157:H7 str. TW14359 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_003080442.1 4625407 D 544404 CDS YP_003080443.1 254795606 8219211 4627522..4628211 1 NC_013008.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4628211 trmH 8219211 trmH Escherichia coli O157:H7 str. TW14359 tRNA guanosine-2'-O-methyltransferase YP_003080443.1 4627522 D 544404 CDS YP_003080444.1 254795607 8219212 4628217..4630298 1 NC_013008.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4630298 recG 8219212 recG Escherichia coli O157:H7 str. TW14359 ATP-dependent DNA helicase RecG YP_003080444.1 4628217 D 544404 CDS YP_003080445.1 254795608 8219213 complement(4630283..4631149) 1 NC_013008.1 hypothetical protein 4631149 8219213 ECSP_4647 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080445.1 4630283 R 544404 CDS YP_003080446.1 254795609 8219214 complement(4631152..4632357) 1 NC_013008.1 glutamate transporter 4632357 gltS 8219214 gltS Escherichia coli O157:H7 str. TW14359 glutamate transporter YP_003080446.1 4631152 R 544404 CDS YP_003080447.1 254795610 8219215 4632637..4634028 1 NC_013008.1 transporter 4634028 yicE 8219215 yicE Escherichia coli O157:H7 str. TW14359 transporter YP_003080447.1 4632637 D 544404 CDS YP_003080448.1 254795611 8219216 4634149..4635858 1 NC_013008.1 hypothetical protein 4635858 yicH 8219216 yicH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080448.1 4634149 D 544404 CDS YP_003080449.1 254795612 8219217 complement(4635911..4638229) 1 NC_013008.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 4638229 yicI 8219217 yicI Escherichia coli O157:H7 str. TW14359 alpha-xylosidase YicI YP_003080449.1 4635911 R 544404 CDS YP_003080450.1 254795613 8219218 complement(4638239..4639621) 1 NC_013008.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4639621 yicJ 8219218 yicJ Escherichia coli O157:H7 str. TW14359 transporter YP_003080450.1 4638239 R 544404 CDS YP_003080451.1 254795614 8219219 4640204..4641385 1 NC_013008.1 integrase for prophage 933L and the LEE pathogenicity island 4641385 intL 8219219 intL Escherichia coli O157:H7 str. TW14359 integrase for prophage 933L and the LEE pathogenicity island YP_003080451.1 4640204 D 544404 CDS YP_003080452.1 254795615 8219220 4641484..4641834 1 NC_013008.1 hypothetical protein 4641834 8219220 ECSP_4654 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080452.1 4641484 D 544404 CDS YP_003080453.1 254795616 8219221 4642023..4642700 1 NC_013008.1 transposase 4642700 8219221 ECSP_4655 Escherichia coli O157:H7 str. TW14359 transposase YP_003080453.1 4642023 D 544404 CDS YP_003080454.1 254795617 8219222 4642951..4643325 1 NC_013008.1 hypothetical protein 4643325 8219222 ECSP_4656 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080454.1 4642951 D 544404 CDS YP_003080455.1 254795618 8219223 4643322..4643813 1 NC_013008.1 hypothetical protein 4643813 8219223 ECSP_4657 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080455.1 4643322 D 544404 CDS YP_003080456.1 254795619 8219224 4643825..4644022 1 NC_013008.1 hypothetical protein 4644022 8219224 ECSP_4658 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080456.1 4643825 D 544404 CDS YP_003080457.1 254795620 8219226 4644964..4645065 1 NC_013008.1 hypothetical protein 4645065 8219226 ECSP_4660 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080457.1 4644964 D 544404 CDS YP_003080458.1 254795621 8219227 4645225..4645605 1 NC_013008.1 transposase, ISEc8 4645605 8219227 ECSP_4661 Escherichia coli O157:H7 str. TW14359 transposase, ISEc8 YP_003080458.1 4645225 D 544404 CDS YP_003080459.1 254795622 8219228 4645602..4645949 1 NC_013008.1 transposase 4645949 8219228 ECSP_4662 Escherichia coli O157:H7 str. TW14359 transposase YP_003080459.1 4645602 D 544404 CDS YP_003080460.1 254795623 8219229 4645999..4647537 1 NC_013008.1 transposase, ISEc8 4647537 8219229 ECSP_4663 Escherichia coli O157:H7 str. TW14359 transposase, ISEc8 YP_003080460.1 4645999 D 544404 CDS YP_003080461.1 254795624 8219230 complement(4647977..4648096) 1 NC_013008.1 hypothetical protein 4648096 8219230 ECSP_4664 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080461.1 4647977 R 544404 CDS YP_003080462.1 254795625 8219231 complement(4648402..4649148) 1 NC_013008.1 LEE-encoded type III effector 4649148 espF 8219231 espF Escherichia coli O157:H7 str. TW14359 LEE-encoded type III effector YP_003080462.1 4648402 R 544404 CDS YP_003080463.1 254795626 8219232 complement(4649233..4649511) 1 NC_013008.1 LEE-encoded type III secretion system factor 4649511 orf29 8219232 orf29 Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080463.1 4649233 R 544404 CDS YP_003080464.1 254795627 8219233 complement(4649517..4649738) 1 NC_013008.1 LEE-encoded type III secretion system component 4649738 escF 8219233 escF Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system component YP_003080464.1 4649517 R 544404 CDS YP_003080465.1 254795628 8219234 complement(4649774..4650181) 1 NC_013008.1 chaperone 4650181 8219234 ECSP_4668 Escherichia coli O157:H7 str. TW14359 chaperone YP_003080465.1 4649774 R 544404 CDS YP_003080466.1 254795629 8219235 complement(4650188..4651126) 1 NC_013008.1 hypothetical protein EspB 4651126 espB 8219235 espB Escherichia coli O157:H7 str. TW14359 hypothetical protein EspB YP_003080466.1 4650188 R 544404 CDS YP_003080467.1 254795630 8219236 complement(4651147..4652271) 1 NC_013008.1 hypothetical protein EspD 4652271 espD 8219236 espD Escherichia coli O157:H7 str. TW14359 hypothetical protein EspD YP_003080467.1 4651147 R 544404 CDS YP_003080468.1 254795631 8219237 complement(4652284..4652862) 1 NC_013008.1 hypothetical protein EspA 4652862 espA 8219237 espA Escherichia coli O157:H7 str. TW14359 hypothetical protein EspA YP_003080468.1 4652284 R 544404 CDS YP_003080469.1 254795632 8219238 complement(4652921..4653976) 1 NC_013008.1 LEE-encoded type III secretion system component 4653976 sepL 8219238 sepL Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system component YP_003080469.1 4652921 R 544404 CDS YP_003080470.1 254795633 8219239 4654119..4655339 1 NC_013008.1 LEE-encoded type III secretion system component 4655339 escD 8219239 escD Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system component YP_003080470.1 4654119 D 544404 CDS YP_003080471.1 254795634 8219240 complement(4655603..4658407) 1 NC_013008.1 intimin adherence protein 4658407 eae 8219240 eae Escherichia coli O157:H7 str. TW14359 intimin adherence protein YP_003080471.1 4655603 R 544404 CDS YP_003080472.1 254795635 8219241 complement(4658467..4658937) 1 NC_013008.1 molecular chaperone 4658937 cesT 8219241 cesT Escherichia coli O157:H7 str. TW14359 molecular chaperone YP_003080472.1 4658467 R 544404 CDS YP_003080473.1 254795636 8219242 complement(4659075..4660751) 1 NC_013008.1 translocated intimin receptor protein 4660751 tir 8219242 tir Escherichia coli O157:H7 str. TW14359 translocated intimin receptor protein YP_003080473.1 4659075 R 544404 CDS YP_003080474.1 254795637 8219243 complement(4661175..4661786) 1 NC_013008.1 similar to mitochondrial associated type III effector protein; type III effector protein 4661786 8219243 ECSP_4677 Escherichia coli O157:H7 str. TW14359 type III effector protein YP_003080474.1 4661175 R 544404 CDS YP_003080475.1 254795638 8219244 4662052..4662435 1 NC_013008.1 chaperone for type III secretion of EspF 4662435 cesF 8219244 cesF Escherichia coli O157:H7 str. TW14359 chaperone for type III secretion of EspF YP_003080475.1 4662052 D 544404 CDS YP_003080476.1 254795639 8219245 complement(4662633..4663139) 1 NC_013008.1 LEE-encoded type III effector 4663139 espH 8219245 espH Escherichia coli O157:H7 str. TW14359 LEE-encoded type III effector YP_003080476.1 4662633 R 544404 CDS YP_003080477.1 254795640 8219246 complement(4663170..4664087) 1 NC_013008.1 LEE-encoded type III secretion system factor 4664087 escQ 8219246 escQ Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080477.1 4663170 R 544404 CDS YP_003080478.1 254795641 8219247 complement(4664050..4664466) 1 NC_013008.1 LEE-encoded type III secretion system factor 4664466 orf16 8219247 orf16 Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080478.1 4664050 R 544404 CDS YP_003080479.1 254795642 8219248 complement(4664459..4664836) 1 NC_013008.1 LEE-encoded type III secretion system factor 4664836 orf15 8219248 orf15 Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080479.1 4664459 R 544404 CDS YP_003080480.1 254795643 8219249 complement(4664839..4666179) 1 NC_013008.1 LEE-encoded type III secretion system factor 4666179 escN 8219249 escN Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080480.1 4664839 R 544404 CDS YP_003080481.1 254795644 8219250 complement(4666163..4668190) 1 NC_013008.1 LEE-encoded type III secretion system factor 4668190 escV 8219250 escV Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080481.1 4666163 R 544404 CDS YP_003080482.1 254795645 8219251 complement(4668187..4668540) 1 NC_013008.1 LEE-encoded type III secretion system factor 4668540 orf12 8219251 orf12 Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080482.1 4668187 R 544404 CDS YP_003080483.1 254795646 8219252 4668725..4669024 1 NC_013008.1 translocated effector protein 4669024 espZ 8219252 espZ Escherichia coli O157:H7 str. TW14359 translocated effector protein YP_003080483.1 4668725 D 544404 CDS YP_003080484.1 254795647 8219253 4669057..4669485 1 NC_013008.1 LEE-encoded type III secretion system component 4669485 escI 8219253 escI Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system component YP_003080484.1 4669057 D 544404 CDS YP_003080485.1 254795648 8219254 4669488..4670060 1 NC_013008.1 LEE-encoded type III secretion system factor 4670060 escJ 8219254 escJ Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080485.1 4669488 D 544404 CDS YP_003080486.1 254795649 8219255 4670066..4670521 1 NC_013008.1 LEE-encoded type III secretion system component 4670521 sepD 8219255 sepD Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system component YP_003080486.1 4670066 D 544404 CDS YP_003080487.1 254795650 8219256 4670521..4672059 1 NC_013008.1 type III needle complex subunit 4672059 escC 8219256 escC Escherichia coli O157:H7 str. TW14359 type III needle complex subunit YP_003080487.1 4670521 D 544404 CDS YP_003080488.1 254795651 8219257 4672073..4672528 1 NC_013008.1 LEE-encoded type III secretion system factor 4672528 cesD 8219257 cesD Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080488.1 4672073 D 544404 CDS YP_003080489.1 254795652 8219258 complement(4672912..4673325) 1 NC_013008.1 LEE-encoded positive regulator of transcription 4673325 grlA 8219258 grlA Escherichia coli O157:H7 str. TW14359 LEE-encoded positive regulator of transcription YP_003080489.1 4672912 R 544404 CDS YP_003080490.1 254795653 8219259 complement(4673380..4673751) 1 NC_013008.1 negative regulator GrlR 4673751 grlR 8219259 grlR Escherichia coli O157:H7 str. TW14359 negative regulator GrlR YP_003080490.1 4673380 R 544404 CDS YP_003080491.1 254795654 8219260 4673947..4674405 1 NC_013008.1 lytic transglycosylase 4674405 etgA 8219260 etgA Escherichia coli O157:H7 str. TW14359 lytic transglycosylase YP_003080491.1 4673947 D 544404 CDS YP_003080492.1 254795655 8219261 complement(4674402..4675439) 1 NC_013008.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli; secretion system apparatus protein SsaU 4675439 escU 8219261 escU Escherichia coli O157:H7 str. TW14359 secretion system apparatus protein SsaU YP_003080492.1 4674402 R 544404 CDS YP_003080493.1 254795656 8219262 complement(4675432..4676208) 1 NC_013008.1 LEE-encoded type III secretion system factor 4676208 escT 8219262 escT Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080493.1 4675432 R 544404 CDS YP_003080494.1 254795657 8219263 complement(4676208..4676477) 1 NC_013008.1 LEE-encoded type III secretion system factor 4676477 escS 8219263 escS Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080494.1 4676208 R 544404 CDS YP_003080495.1 254795658 8219264 complement(4676477..4677130) 1 NC_013008.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein 4677130 escR 8219264 escR Escherichia coli O157:H7 str. TW14359 type III secretion system protein YP_003080495.1 4676477 R 544404 CDS YP_003080496.1 254795659 8219265 complement(4677135..4677749) 1 NC_013008.1 LEE-encoded type III secretion system factor 4677749 escL 8219265 escL Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080496.1 4677135 R 544404 CDS YP_003080497.1 254795660 8219266 complement(4677775..4678374) 1 NC_013008.1 LEE-encoded type III secretion system factor 4678374 orf4 8219266 orf4 Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080497.1 4677775 R 544404 CDS YP_003080498.1 254795661 8219267 complement(4678371..4678694) 1 NC_013008.1 LEE-encoded chaperone 4678694 cesA 8219267 cesA Escherichia coli O157:H7 str. TW14359 LEE-encoded chaperone YP_003080498.1 4678371 R 544404 CDS YP_003080499.1 254795662 8219268 complement(4678698..4678916) 1 NC_013008.1 LEE-encoded type III secretion system factor 4678916 escE 8219268 escE Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080499.1 4678698 R 544404 CDS YP_003080500.1 254795663 8219269 complement(4678931..4679302) 1 NC_013008.1 enterocyte effacement (LEE)-encoded regulator 4679302 ler 8219269 ler Escherichia coli O157:H7 str. TW14359 enterocyte effacement (LEE)-encoded regulator YP_003080500.1 4678931 R 544404 CDS YP_003080501.1 254795664 8219270 4680565..4681761 1 NC_013008.1 LEE-encoded type III effector 4681761 espG 8219270 espG Escherichia coli O157:H7 str. TW14359 LEE-encoded type III effector YP_003080501.1 4680565 D 544404 CDS YP_003080502.1 254795665 8219271 4681889..4682707 1 NC_013008.1 LEE-encoded type III secretion system factor 4682707 rorf1 8219271 rorf1 Escherichia coli O157:H7 str. TW14359 LEE-encoded type III secretion system factor YP_003080502.1 4681889 D 544404 CDS YP_003080503.1 254795666 8219272 4683727..4684650 1 NC_013008.1 inner membrane protein 4684650 yicL 8219272 yicL Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080503.1 4683727 D 544404 CDS YP_003080504.1 254795667 8219273 complement(4684654..4685472) 1 NC_013008.1 cytoplasmic membrane lipoprotein-28 4685472 nlpA 8219273 nlpA Escherichia coli O157:H7 str. TW14359 cytoplasmic membrane lipoprotein-28 YP_003080504.1 4684654 R 544404 CDS YP_003080505.1 254795668 8219274 4685694..4685987 1 NC_013008.1 hypothetical protein 4685987 yicS 8219274 yicS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080505.1 4685694 D 544404 CDS YP_003080506.1 254795669 8219275 complement(4686028..4687218) 1 NC_013008.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4687218 nepI 8219275 nepI Escherichia coli O157:H7 str. TW14359 ribonucleoside transporter YP_003080506.1 4686028 R 544404 CDS YP_003080507.1 254795670 8219276 4687452..4687805 1 NC_013008.1 hypothetical protein 4687805 8219276 ECSP_4710 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080507.1 4687452 D 544404 CDS YP_003080508.1 254795671 8219277 4687789..4688112 1 NC_013008.1 hypothetical protein 4688112 8219277 ECSP_4711 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080508.1 4687789 D 544404 CDS YP_003080509.1 254795672 8219278 complement(4688228..4688680) 1 NC_013008.1 hypothetical protein 4688680 yicN 8219278 yicN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080509.1 4688228 R 544404 CDS YP_003080510.1 254795673 8219280 4690241..4692007 1 NC_013008.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4692007 ade 8219280 ade Escherichia coli O157:H7 str. TW14359 cryptic adenine deaminase YP_003080510.1 4690241 D 544404 CDS YP_003080511.1 254795674 8219281 complement(4692053..4693444) 1 NC_013008.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4693444 uhpT 8219281 uhpT Escherichia coli O157:H7 str. TW14359 sugar phosphate antiporter YP_003080511.1 4692053 R 544404 CDS YP_003080512.1 254795675 8219282 complement(4693582..4694901) 1 NC_013008.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4694901 uhpC 8219282 uhpC Escherichia coli O157:H7 str. TW14359 regulatory protein UhpC YP_003080512.1 4693582 R 544404 CDS YP_003080513.1 254795676 8219283 complement(4694911..4696413) 1 NC_013008.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4696413 uhpB 8219283 uhpB Escherichia coli O157:H7 str. TW14359 sensory histidine kinase UhpB YP_003080513.1 4694911 R 544404 CDS YP_003080514.1 254795677 8219284 complement(4696413..4697003) 1 NC_013008.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4697003 uhpA 8219284 uhpA Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator UhpA YP_003080514.1 4696413 R 544404 CDS YP_003080515.1 254795678 8219287 complement(4700424..4700714) 1 NC_013008.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4700714 ilvN 8219287 ilvN Escherichia coli O157:H7 str. TW14359 acetolactate synthase 1 regulatory subunit YP_003080515.1 4700424 R 544404 CDS YP_003080516.1 254795679 8219288 complement(4700718..4702406) 1 NC_013008.1 acetolactate synthase catalytic subunit 4702406 ilvB 8219288 ilvB Escherichia coli O157:H7 str. TW14359 acetolactate synthase catalytic subunit YP_003080516.1 4700718 R 544404 CDS YP_003080517.1 254795680 8219289 4702390..4702887 1 NC_013008.1 hypothetical protein 4702887 8219289 ECSP_4723 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080517.1 4702390 D 544404 CDS YP_003080518.1 254795681 8219290 4703344..4703517 1 NC_013008.1 hypothetical protein 4703517 8219290 ECSP_4724 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080518.1 4703344 D 544404 CDS YP_003080519.1 254795682 8219291 4703544..4704728 1 NC_013008.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4704728 emrD 8219291 emrD Escherichia coli O157:H7 str. TW14359 multidrug resistance protein D YP_003080519.1 4703544 D 544404 CDS YP_003080520.1 254795683 8219292 complement(4704736..4705233) 1 NC_013008.1 DNA-binding transcriptional regulator 4705233 yidF 8219292 yidF Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080520.1 4704736 R 544404 CDS YP_003080521.1 254795684 8219293 complement(4705230..4705592) 1 NC_013008.1 inner membrane protein 4705592 yidG 8219293 yidG Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080521.1 4705230 R 544404 CDS YP_003080522.1 254795685 8219294 complement(4705582..4705929) 1 NC_013008.1 hypothetical protein 4705929 yidH 8219294 yidH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080522.1 4705582 R 544404 CDS YP_003080523.1 254795686 8219295 4706038..4706487 1 NC_013008.1 inner membrane protein 4706487 yidI 8219295 yidI Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080523.1 4706038 D 544404 CDS YP_003080524.1 254795687 8219296 complement(4706534..4708027) 1 NC_013008.1 sulfatase/phosphatase 4708027 yidJ 8219296 yidJ Escherichia coli O157:H7 str. TW14359 sulfatase/phosphatase YP_003080524.1 4706534 R 544404 CDS YP_003080525.1 254795688 8219297 complement(4708024..4709739) 1 NC_013008.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4709739 yidK 8219297 yidK Escherichia coli O157:H7 str. TW14359 symporter YidK YP_003080525.1 4708024 R 544404 CDS YP_003080526.1 254795689 8219298 4709876..4710799 1 NC_013008.1 DNA-binding transcriptional regulator 4710799 yidL 8219298 yidL Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080526.1 4709876 D 544404 CDS YP_003080527.1 254795690 8219299 complement(4710796..4712118) 1 NC_013008.1 6-phospho-beta-glucosidase 4712118 8219299 ECSP_4733 Escherichia coli O157:H7 str. TW14359 6-phospho-beta-glucosidase YP_003080527.1 4710796 R 544404 CDS YP_003080528.1 254795691 8219300 complement(4712118..4713734) 1 NC_013008.1 PTS component 4713734 8219300 ECSP_4734 Escherichia coli O157:H7 str. TW14359 PTS component YP_003080528.1 4712118 R 544404 CDS YP_003080529.1 254795692 8219301 4714030..4714746 1 NC_013008.1 DNA-binding transcriptional regulator 4714746 yidP 8219301 yidP Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080529.1 4714030 D 544404 CDS YP_003080530.1 254795693 8219302 complement(4714743..4716404) 1 NC_013008.1 hypothetical protein 4716404 yidE 8219302 yidE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080530.1 4714743 R 544404 CDS YP_003080531.1 254795694 8219303 complement(4716600..4717028) 1 NC_013008.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4717028 ibpB 8219303 ibpB Escherichia coli O157:H7 str. TW14359 heat shock chaperone IbpB YP_003080531.1 4716600 R 544404 CDS YP_003080532.1 254795695 8219304 complement(4717140..4717553) 1 NC_013008.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4717553 ibpA 8219304 ibpA Escherichia coli O157:H7 str. TW14359 heat shock protein IbpA YP_003080532.1 4717140 R 544404 CDS YP_003080533.1 254795696 8219305 4717859..4718191 1 NC_013008.1 hypothetical protein 4718191 yidQ 8219305 yidQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080533.1 4717859 D 544404 CDS YP_003080534.1 254795697 8219306 complement(4718193..4719407) 1 NC_013008.1 hypothetical protein 4719407 yidR 8219306 yidR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080534.1 4718193 R 544404 CDS YP_003080535.1 254795698 8219307 4719508..4720572 1 NC_013008.1 FAD/NAD(P)-binding domain; oxidoreductase 4720572 cbrA 8219307 cbrA Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003080535.1 4719508 D 544404 CDS YP_003080536.1 254795699 8219308 4720818..4721474 1 NC_013008.1 hypothetical protein 4721474 yidX 8219308 yidX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080536.1 4720818 D 544404 CDS YP_003080537.1 254795700 8219309 complement(4721520..4722332) 1 NC_013008.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4722332 yidA 8219309 yidA Escherichia coli O157:H7 str. TW14359 sugar phosphatase YP_003080537.1 4721520 R 544404 CDS YP_003080538.1 254795701 8219310 complement(4722447..4722845) 1 NC_013008.1 hypothetical protein 4722845 yidB 8219310 yidB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080538.1 4722447 R 544404 CDS YP_003080539.1 254795702 8219311 complement(4723085..4725499) 1 NC_013008.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4725499 gyrB 8219311 gyrB Escherichia coli O157:H7 str. TW14359 DNA gyrase subunit B YP_003080539.1 4723085 R 544404 CDS YP_003080540.1 254795703 8219312 complement(4725528..4726601) 1 NC_013008.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4726601 recF 8219312 recF Escherichia coli O157:H7 str. TW14359 recombination protein F YP_003080540.1 4725528 R 544404 CDS YP_003080541.1 254795704 8219313 complement(4726601..4727701) 1 NC_013008.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4727701 dnaN 8219313 dnaN Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit beta YP_003080541.1 4726601 R 544404 CDS YP_003080542.1 254795705 8219314 complement(4727706..4729109) 1 NC_013008.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 4729109 dnaA 8219314 dnaA Escherichia coli O157:H7 str. TW14359 chromosomal replication initiation protein YP_003080542.1 4727706 R 544404 CDS YP_003080543.1 254795706 8219315 4729716..4729856 1 NC_013008.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4729856 rpmH 8219315 rpmH Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L34 YP_003080543.1 4729716 D 544404 CDS YP_003080544.1 254795707 8219316 4729873..4730232 1 NC_013008.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4730232 rnpA 8219316 rnpA Escherichia coli O157:H7 str. TW14359 ribonuclease P YP_003080544.1 4729873 D 544404 CDS YP_003080545.1 254795708 8219317 4730456..4732102 1 NC_013008.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4732102 yidC 8219317 yidC Escherichia coli O157:H7 str. TW14359 inner membrane protein translocase component YidC YP_003080545.1 4730456 D 544404 CDS YP_003080546.1 254795709 8219318 4732208..4733572 1 NC_013008.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4733572 trmE 8219318 trmE Escherichia coli O157:H7 str. TW14359 tRNA modification GTPase TrmE YP_003080546.1 4732208 D 544404 CDS YP_003080547.1 254795710 8219319 complement(4733722..4733943) 1 NC_013008.1 hypothetical protein 4733943 8219319 ECSP_4753 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080547.1 4733722 R 544404 CDS YP_003080548.1 254795711 8219320 complement(4733903..4735891) 1 NC_013008.1 protein with ShET2 enterotoxin, N-terminal region domain 4735891 8219320 ECSP_4754 Escherichia coli O157:H7 str. TW14359 protein with ShET2 enterotoxin, N-terminal region domain YP_003080548.1 4733903 R 544404 CDS YP_003080549.1 254795712 8219321 4736282..4736356 1 NC_013008.1 tryptophanase leader peptide 4736356 tnaC 8219321 tnaC Escherichia coli O157:H7 str. TW14359 tryptophanase leader peptide YP_003080549.1 4736282 D 544404 CDS YP_003080550.1 254795713 8219322 4736577..4737992 1 NC_013008.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4737992 tnaA 8219322 tnaA Escherichia coli O157:H7 str. TW14359 tryptophanase YP_003080550.1 4736577 D 544404 CDS YP_003080551.1 254795714 8219323 4738083..4739330 1 NC_013008.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4739330 tnaB 8219323 tnaB Escherichia coli O157:H7 str. TW14359 tryptophan permease TnaB YP_003080551.1 4738083 D 544404 CDS YP_003080552.1 254795715 8219324 4739462..4740637 1 NC_013008.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4740637 mdtL 8219324 mdtL Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein MdtL YP_003080552.1 4739462 D 544404 CDS YP_003080553.1 254795716 8219325 4740612..4741571 1 NC_013008.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4741571 yidZ 8219325 yidZ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YidZ YP_003080553.1 4740612 D 544404 CDS YP_003080554.1 254795717 8219326 4741728..4742477 1 NC_013008.1 phosphopantetheinyl transferase 4742477 yieE 8219326 yieE Escherichia coli O157:H7 str. TW14359 phosphopantetheinyl transferase YP_003080554.1 4741728 D 544404 CDS YP_003080555.1 254795718 8219327 4742499..4743065 1 NC_013008.1 chromate reductase, Class I, flavoprotein 4743065 yieF 8219327 yieF Escherichia coli O157:H7 str. TW14359 chromate reductase, Class I, flavoprotein YP_003080555.1 4742499 D 544404 CDS YP_003080556.1 254795719 8219328 complement(4743119..4744456) 1 NC_013008.1 inner membrane protein 4744456 yieG 8219328 yieG Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080556.1 4743119 R 544404 CDS YP_003080557.1 254795720 8219329 4744622..4745287 1 NC_013008.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4745287 yieH 8219329 yieH Escherichia coli O157:H7 str. TW14359 6-phosphogluconate phosphatase YP_003080557.1 4744622 D 544404 CDS YP_003080558.1 254795721 8219330 complement(4745424..4747832) 1 NC_013008.1 non-LEE-encoded type III effector 4747832 espY4 8219330 espY4 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003080558.1 4745424 R 544404 CDS YP_003080559.1 254795722 8219332 complement(4752699..4753424) 1 NC_013008.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4753424 phoU 8219332 phoU Escherichia coli O157:H7 str. TW14359 transcriptional regulator PhoU YP_003080559.1 4752699 R 544404 CDS YP_003080560.1 254795723 8219333 complement(4753439..4754212) 1 NC_013008.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4754212 pstB 8219333 pstB Escherichia coli O157:H7 str. TW14359 phosphate transporter ATP-binding protein YP_003080560.1 4753439 R 544404 CDS YP_003080561.1 254795724 8219334 complement(4754395..4755285) 1 NC_013008.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4755285 pstA 8219334 pstA Escherichia coli O157:H7 str. TW14359 phosphate transporter permease subunit PtsA YP_003080561.1 4754395 R 544404 CDS YP_003080562.1 254795725 8219335 complement(4755285..4756244) 1 NC_013008.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4756244 pstC 8219335 pstC Escherichia coli O157:H7 str. TW14359 phosphate transporter permease subunit PstC YP_003080562.1 4755285 R 544404 CDS YP_003080563.1 254795726 8219336 complement(4756331..4757371) 1 NC_013008.1 phosphate ABC transporter substrate-binding protein 4757371 pstS 8219336 pstS Escherichia coli O157:H7 str. TW14359 phosphate ABC transporter substrate-binding protein YP_003080563.1 4756331 R 544404 CDS YP_003080564.1 254795727 8219337 4757438..4757554 1 NC_013008.1 hypothetical protein 4757554 8219337 ECSP_4771 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080564.1 4757438 D 544404 CDS YP_003080565.1 254795728 8219338 complement(4757583..4758665) 1 NC_013008.1 fimbrial protein 4758665 8219338 ECSP_4772 Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003080565.1 4757583 R 544404 CDS YP_003080566.1 254795729 8219339 complement(4758693..4759763) 1 NC_013008.1 fimbrial protein 4759763 lpfD2 8219339 lpfD2 Escherichia coli O157:H7 str. TW14359 fimbrial protein YP_003080566.1 4758693 R 544404 CDS YP_003080567.1 254795730 8219340 complement(4759775..4762309) 1 NC_013008.1 fimbrial usher 4762309 lpfC 8219340 lpfC Escherichia coli O157:H7 str. TW14359 fimbrial usher YP_003080567.1 4759775 R 544404 CDS YP_003080568.1 254795731 8219341 complement(4762331..4762492) 1 NC_013008.1 fimbrial chaperone 4762492 8219341 ECSP_4775 Escherichia coli O157:H7 str. TW14359 fimbrial chaperone YP_003080568.1 4762331 R 544404 CDS YP_003080569.1 254795732 8219342 complement(4762633..4763016) 1 NC_013008.1 fimbrial chaperone 4763016 lpfB2 8219342 lpfB2 Escherichia coli O157:H7 str. TW14359 fimbrial chaperone YP_003080569.1 4762633 R 544404 CDS YP_003080570.1 254795733 8219343 complement(4763120..4763722) 1 NC_013008.1 major fimbrial subunit 4763722 lpfA2 8219343 lpfA2 Escherichia coli O157:H7 str. TW14359 major fimbrial subunit YP_003080570.1 4763120 R 544404 CDS YP_003080572.1 254795735 8219345 complement(4764422..4766251) 1 NC_013008.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4766251 glmS 8219345 glmS Escherichia coli O157:H7 str. TW14359 glucosamine--fructose-6-phosphate aminotransferase YP_003080572.1 4764422 R 544404 CDS YP_003080573.1 254795736 8219346 complement(4766413..4767783) 1 NC_013008.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4767783 glmU 8219346 glmU Escherichia coli O157:H7 str. TW14359 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_003080573.1 4766413 R 544404 CDS YP_003080574.1 254795737 8219347 complement(4768135..4768554) 1 NC_013008.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 4768554 atpC 8219347 atpC Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit epsilon YP_003080574.1 4768135 R 544404 CDS YP_003080575.1 254795738 8219348 complement(4768575..4769957) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 4769957 atpD 8219348 atpD Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit beta YP_003080575.1 4768575 R 544404 CDS YP_003080576.1 254795739 8219349 complement(4769984..4770847) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 4770847 atpG 8219349 atpG Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit gamma YP_003080576.1 4769984 R 544404 CDS YP_003080577.1 254795740 8219350 complement(4770898..4772439) 1 NC_013008.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 4772439 atpA 8219350 atpA Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit alpha YP_003080577.1 4770898 R 544404 CDS YP_003080578.1 254795741 8219351 complement(4772452..4772985) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4772985 atpH 8219351 atpH Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit delta YP_003080578.1 4772452 R 544404 CDS YP_003080579.1 254795742 8219352 complement(4773000..4773470) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 4773470 atpF 8219352 atpF Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit B YP_003080579.1 4773000 R 544404 CDS YP_003080580.1 254795743 8219353 complement(4773532..4773771) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4773771 atpE 8219353 atpE Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit C YP_003080580.1 4773532 R 544404 CDS YP_003080581.1 254795744 8219354 complement(4773818..4774633) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4774633 atpB 8219354 atpB Escherichia coli O157:H7 str. TW14359 ATP synthase F0F1 subunit A YP_003080581.1 4773818 R 544404 CDS YP_003080582.1 254795745 8219355 complement(4774642..4775022) 1 NC_013008.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4775022 atpI 8219355 atpI Escherichia coli O157:H7 str. TW14359 F0F1 ATP synthase subunit I YP_003080582.1 4774642 R 544404 CDS YP_003080583.1 254795746 8219356 complement(4775639..4776262) 1 NC_013008.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4776262 gidB 8219356 gidB Escherichia coli O157:H7 str. TW14359 16S rRNA methyltransferase GidB YP_003080583.1 4775639 R 544404 CDS YP_003080584.1 254795747 8219357 complement(4776326..4778215) 1 NC_013008.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4778215 gidA 8219357 gidA Escherichia coli O157:H7 str. TW14359 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_003080584.1 4776326 R 544404 CDS YP_003080585.1 254795748 8219358 complement(4778594..4779037) 1 NC_013008.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4779037 mioC 8219358 mioC Escherichia coli O157:H7 str. TW14359 flavodoxin YP_003080585.1 4778594 R 544404 CDS YP_003080586.1 254795749 8219359 complement(4779127..4779585) 1 NC_013008.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4779585 asnC 8219359 asnC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator AsnC YP_003080586.1 4779127 R 544404 CDS YP_003080587.1 254795750 8219360 4779737..4780729 1 NC_013008.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4780729 asnA 8219360 asnA Escherichia coli O157:H7 str. TW14359 asparagine synthetase AsnA YP_003080587.1 4779737 D 544404 CDS YP_003080588.1 254795751 8219361 complement(4780734..4782185) 1 NC_013008.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4782185 yieM 8219361 yieM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080588.1 4780734 R 544404 CDS YP_003080589.1 254795752 8219362 complement(4782179..4783675) 1 NC_013008.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4783675 ravA 8219362 ravA Escherichia coli O157:H7 str. TW14359 regulatory ATPase RavA YP_003080589.1 4782179 R 544404 CDS YP_003080590.1 254795753 8219363 4783898..4785766 1 NC_013008.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4785766 trkD 8219363 trkD Escherichia coli O157:H7 str. TW14359 potassium transport protein Kup YP_003080590.1 4783898 D 544404 CDS YP_003080591.1 254795754 8219364 4785933..4786352 1 NC_013008.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4786352 rbsD 8219364 rbsD Escherichia coli O157:H7 str. TW14359 D-ribose pyranase YP_003080591.1 4785933 D 544404 CDS YP_003080592.1 254795755 8219365 4786360..4787865 1 NC_013008.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4787865 rbsA 8219365 rbsA Escherichia coli O157:H7 str. TW14359 D-ribose transporter ATP binding protein YP_003080592.1 4786360 D 544404 CDS YP_003080593.1 254795756 8219366 4787870..4788835 1 NC_013008.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4788835 rbsC 8219366 rbsC Escherichia coli O157:H7 str. TW14359 ribose ABC transporter permease YP_003080593.1 4787870 D 544404 CDS YP_003080594.1 254795757 8219367 4788860..4789750 1 NC_013008.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4789750 rbsB 8219367 rbsB Escherichia coli O157:H7 str. TW14359 D-ribose transporter subunit RbsB YP_003080594.1 4788860 D 544404 CDS YP_003080595.1 254795758 8219368 4789876..4790805 1 NC_013008.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4790805 rbsK 8219368 rbsK Escherichia coli O157:H7 str. TW14359 ribokinase YP_003080595.1 4789876 D 544404 CDS YP_003080596.1 254795759 8219369 4790809..4791801 1 NC_013008.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4791801 rbsR 8219369 rbsR Escherichia coli O157:H7 str. TW14359 transcriptional repressor RbsR YP_003080596.1 4790809 D 544404 CDS YP_003080597.1 254795760 8219370 complement(4791767..4793194) 1 NC_013008.1 multidrug or homocysteine efflux system 4793194 hsrA 8219370 hsrA Escherichia coli O157:H7 str. TW14359 multidrug or homocysteine efflux system YP_003080597.1 4791767 R 544404 CDS YP_003080598.1 254795761 8219371 complement(4793217..4793909) 1 NC_013008.1 transcriptional regulator 4793909 yieP 8219371 yieP Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003080598.1 4793217 R 544404 CDS YP_003080599.1 254795762 8219372 complement(4794132..4794245) 1 NC_013008.1 hypothetical protein 4794245 8219372 ECSP_4806 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080599.1 4794132 R 544404 CDS YP_003080600.1 254795763 8219379 complement(4799711..4800550) 1 NC_013008.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4800550 hdfR 8219379 hdfR Escherichia coli O157:H7 str. TW14359 transcriptional regulator HdfR YP_003080600.1 4799711 R 544404 CDS YP_003080601.1 254795764 8219380 4800669..4801007 1 NC_013008.1 hypothetical protein 4801007 yifE 8219380 yifE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080601.1 4800669 D 544404 CDS YP_003080602.1 254795765 8219381 complement(4801031..4802551) 1 NC_013008.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 4802551 yifB 8219381 yifB Escherichia coli O157:H7 str. TW14359 ATP-dependent protease YP_003080602.1 4801031 R 544404 CDS YP_003080603.1 254795766 8219382 4802904..4803002 1 NC_013008.1 ilvG operon leader peptide 4803002 ilvL 8219382 ilvL Escherichia coli O157:H7 str. TW14359 ilvG operon leader peptide YP_003080603.1 4802904 D 544404 CDS YP_003080604.1 254795767 8219383 4803142..4804788 1 NC_013008.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4804788 ilvG 8219383 ilvG Escherichia coli O157:H7 str. TW14359 acetolactate synthase 2 catalytic subunit YP_003080604.1 4803142 D 544404 CDS YP_003080605.1 254795768 8219384 4804785..4805048 1 NC_013008.1 acetolactate synthase 2 regulatory subunit 4805048 ilvM 8219384 ilvM Escherichia coli O157:H7 str. TW14359 acetolactate synthase 2 regulatory subunit YP_003080605.1 4804785 D 544404 CDS YP_003080606.1 254795769 8219385 4805068..4805997 1 NC_013008.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4805997 ilvE 8219385 ilvE Escherichia coli O157:H7 str. TW14359 branched-chain amino acid aminotransferase YP_003080606.1 4805068 D 544404 CDS YP_003080607.1 254795770 8219386 4806062..4807912 1 NC_013008.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4807912 ilvD 8219386 ilvD Escherichia coli O157:H7 str. TW14359 dihydroxy-acid dehydratase YP_003080607.1 4806062 D 544404 CDS YP_003080608.1 254795771 8219387 4807915..4809459 1 NC_013008.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4809459 ilvA 8219387 ilvA Escherichia coli O157:H7 str. TW14359 threonine dehydratase YP_003080608.1 4807915 D 544404 CDS YP_003080609.1 254795772 8219388 complement(4809511..4810404) 1 NC_013008.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4810404 ilvY 8219388 ilvY Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator IlvY YP_003080609.1 4809511 R 544404 CDS YP_003080610.1 254795773 8219389 4810554..4812029 1 NC_013008.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4812029 ilvC 8219389 ilvC Escherichia coli O157:H7 str. TW14359 ketol-acid reductoisomerase YP_003080610.1 4810554 D 544404 CDS YP_003080611.1 254795774 8219390 complement(4812075..4812356) 1 NC_013008.1 peptidyl-prolyl cis-trans isomerase C 4812356 ppiC 8219390 ppiC Escherichia coli O157:H7 str. TW14359 peptidyl-prolyl cis-trans isomerase C YP_003080611.1 4812075 R 544404 CDS YP_003080612.1 254795775 8219391 complement(4812555..4813004) 1 NC_013008.1 hypothetical protein 4813004 yifN 8219391 yifN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080612.1 4812555 R 544404 CDS YP_003080613.1 254795776 8219392 4813221..4815242 1 NC_013008.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4815242 rep 8219392 rep Escherichia coli O157:H7 str. TW14359 ATP-dependent DNA helicase Rep YP_003080613.1 4813221 D 544404 CDS YP_003080614.1 254795777 8219393 complement(4815289..4816773) 1 NC_013008.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4816773 gpp 8219393 gpp Escherichia coli O157:H7 str. TW14359 guanosine pentaphosphate phosphohydrolase YP_003080614.1 4815289 R 544404 CDS YP_003080615.1 254795778 8219394 complement(4816909..4818174) 1 NC_013008.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4818174 rhlB 8219394 rhlB Escherichia coli O157:H7 str. TW14359 ATP-dependent RNA helicase RhlB YP_003080615.1 4816909 R 544404 CDS YP_003080616.1 254795779 8219395 4818305..4818634 1 NC_013008.1 thioredoxin 4818634 trxA 8219395 trxA Escherichia coli O157:H7 str. TW14359 thioredoxin YP_003080616.1 4818305 D 544404 CDS YP_003080617.1 254795780 8219396 4818961..4820220 1 NC_013008.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4820220 rho 8219396 rho Escherichia coli O157:H7 str. TW14359 transcription termination factor Rho YP_003080617.1 4818961 D 544404 CDS YP_003080618.1 254795781 8219397 4820230..4820448 1 NC_013008.1 hypothetical protein 4820448 8219397 ECSP_4831 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080618.1 4820230 D 544404 CDS YP_003080619.1 254795782 8219398 4820460..4821563 1 NC_013008.1 UDP-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 4821563 rfe 8219398 rfe Escherichia coli O157:H7 str. TW14359 UDP-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_003080619.1 4820460 D 544404 CDS YP_003080620.1 254795783 8219399 4821575..4822621 1 NC_013008.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4822621 wzzE 8219399 wzzE Escherichia coli O157:H7 str. TW14359 lipopolysaccharide biosynthesis protein WzzE YP_003080620.1 4821575 D 544404 CDS YP_003080621.1 254795784 8219400 4822677..4823807 1 NC_013008.1 UDP-N-acetyl glucosamine-2-epimerase 4823807 rffE 8219400 rffE Escherichia coli O157:H7 str. TW14359 UDP-N-acetyl glucosamine-2-epimerase YP_003080621.1 4822677 D 544404 CDS YP_003080622.1 254795785 8219401 4823804..4825066 1 NC_013008.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4825066 wecC 8219401 wecC Escherichia coli O157:H7 str. TW14359 UDP-N-acetyl-D-mannosamine dehydrogenase YP_003080622.1 4823804 D 544404 CDS YP_003080623.1 254795786 8219402 4825066..4826133 1 NC_013008.1 dTDP-glucose 4,6-dehydratase 4826133 rffG 8219402 rffG Escherichia coli O157:H7 str. TW14359 dTDP-glucose 4,6-dehydratase YP_003080623.1 4825066 D 544404 CDS YP_003080624.1 254795787 8219403 4826152..4827033 1 NC_013008.1 glucose-1-phosphate thymidylyltransferase 4827033 rffH 8219403 rffH Escherichia coli O157:H7 str. TW14359 glucose-1-phosphate thymidylyltransferase YP_003080624.1 4826152 D 544404 CDS YP_003080625.1 254795788 8219404 4827011..4827685 1 NC_013008.1 TDP-fucosamine acetyltransferase 4827685 rffC 8219404 rffC Escherichia coli O157:H7 str. TW14359 TDP-fucosamine acetyltransferase YP_003080625.1 4827011 D 544404 CDS YP_003080626.1 254795789 8219405 4827690..4828820 1 NC_013008.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4828820 rffA 8219405 rffA Escherichia coli O157:H7 str. TW14359 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_003080626.1 4827690 D 544404 CDS YP_003080627.1 254795790 8219406 4828822..4830072 1 NC_013008.1 lipid III translocase 4830072 wzxE 8219406 wzxE Escherichia coli O157:H7 str. TW14359 lipid III translocase YP_003080627.1 4828822 D 544404 CDS YP_003080628.1 254795791 8219407 4830069..4831148 1 NC_013008.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4831148 rffT 8219407 rffT Escherichia coli O157:H7 str. TW14359 4-alpha-L-fucosyltransferase YP_003080628.1 4830069 D 544404 CDS YP_003080629.1 254795792 8219408 4831145..4832497 1 NC_013008.1 enterobacterial common antigen polymerase; common antigen polymerase 4832497 8219408 ECSP_4842 Escherichia coli O157:H7 str. TW14359 common antigen polymerase YP_003080629.1 4831145 D 544404 CDS YP_003080630.1 254795793 8219409 4832500..4833240 1 NC_013008.1 UDP-N-acetyl-D-mannosaminuronic acid transferase 4833240 8219409 ECSP_4843 Escherichia coli O157:H7 str. TW14359 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_003080630.1 4832500 D 544404 CDS YP_003080631.1 254795794 8219410 4833431..4834816 1 NC_013008.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4834816 yifK 8219410 yifK Escherichia coli O157:H7 str. TW14359 transport protein YifK YP_003080631.1 4833431 D 544404 CDS YP_003080632.1 254795795 8219417 4835728..4836963 1 NC_013008.1 regulator of arylsulfatase activity 4836963 aslB 8219417 aslB Escherichia coli O157:H7 str. TW14359 regulator of arylsulfatase activity YP_003080632.1 4835728 D 544404 CDS YP_003080633.1 254795796 8219418 complement(4837131..4838786) 1 NC_013008.1 acrylsulfatase-like enzyme 4838786 aslA 8219418 aslA Escherichia coli O157:H7 str. TW14359 acrylsulfatase-like enzyme YP_003080633.1 4837131 R 544404 CDS YP_003080634.1 254795797 8219419 complement(4838929..4839066) 1 NC_013008.1 hypothetical protein 4839066 8219419 ECSP_4853 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080634.1 4838929 R 544404 CDS YP_003080635.1 254795798 8219420 complement(4839465..4840661) 1 NC_013008.1 protoheme IX biogenesis protein 4840661 hemY 8219420 hemY Escherichia coli O157:H7 str. TW14359 protoheme IX biogenesis protein YP_003080635.1 4839465 R 544404 CDS YP_003080636.1 254795799 8219421 complement(4840664..4841899) 1 NC_013008.1 uroporphyrinogen III C-methyltransferase 4841899 hemX 8219421 hemX Escherichia coli O157:H7 str. TW14359 uroporphyrinogen III C-methyltransferase YP_003080636.1 4840664 R 544404 CDS YP_003080637.1 254795800 8219422 complement(4841921..4842661) 1 NC_013008.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4842661 hemD 8219422 hemD Escherichia coli O157:H7 str. TW14359 uroporphyrinogen-III synthase YP_003080637.1 4841921 R 544404 CDS YP_003080638.1 254795801 8219423 complement(4842658..4843599) 1 NC_013008.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4843599 hemC 8219423 hemC Escherichia coli O157:H7 str. TW14359 porphobilinogen deaminase YP_003080638.1 4842658 R 544404 CDS YP_003080639.1 254795802 8219424 4843986..4846532 1 NC_013008.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4846532 cyaA 8219424 cyaA Escherichia coli O157:H7 str. TW14359 adenylate cyclase YP_003080639.1 4843986 D 544404 CDS YP_003080640.1 254795803 8219425 complement(4846572..4846892) 1 NC_013008.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4846892 cyaY 8219425 cyaY Escherichia coli O157:H7 str. TW14359 frataxin-like protein YP_003080640.1 4846572 R 544404 CDS YP_003080641.1 254795804 8219426 4847355..4847558 1 NC_013008.1 lipoprotein 4847558 yifL 8219426 yifL Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003080641.1 4847355 D 544404 CDS YP_003080642.1 254795805 8219427 4847595..4848419 1 NC_013008.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4848419 dapF 8219427 dapF Escherichia coli O157:H7 str. TW14359 diaminopimelate epimerase YP_003080642.1 4847595 D 544404 CDS YP_003080643.1 254795806 8219428 4848416..4849123 1 NC_013008.1 hypothetical protein 4849123 yigA 8219428 yigA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080643.1 4848416 D 544404 CDS YP_003080644.1 254795807 8219429 4849120..4850016 1 NC_013008.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4850016 xerC 8219429 xerC Escherichia coli O157:H7 str. TW14359 site-specific tyrosine recombinase XerC YP_003080644.1 4849120 D 544404 CDS YP_003080645.1 254795808 8219430 4850016..4850732 1 NC_013008.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4850732 yigB 8219430 yigB Escherichia coli O157:H7 str. TW14359 flavin mononucleotide phosphatase YP_003080645.1 4850016 D 544404 CDS YP_003080646.1 254795809 8219431 4850816..4852978 1 NC_013008.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4852978 uvrD 8219431 uvrD Escherichia coli O157:H7 str. TW14359 DNA-dependent helicase II YP_003080646.1 4850816 D 544404 CDS YP_003080647.1 254795810 8219432 complement(4853023..4853925) 1 NC_013008.1 hypothetical protein 4853925 8219432 ECSP_4866 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080647.1 4853023 R 544404 CDS YP_003080648.1 254795811 8219433 complement(4854008..4854772) 1 NC_013008.1 hypothetical protein 4854772 yigE 8219433 yigE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080648.1 4854008 R 544404 CDS YP_003080649.1 254795812 8219434 4855142..4856092 1 NC_013008.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4856092 corA 8219434 corA Escherichia coli O157:H7 str. TW14359 magnesium/nickel/cobalt transporter CorA YP_003080649.1 4855142 D 544404 CDS YP_003080650.1 254795813 8219435 complement(4856134..4856625) 1 NC_013008.1 hypothetical protein 4856625 8219435 ECSP_4869 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080650.1 4856134 R 544404 CDS YP_003080651.1 254795814 8219436 complement(4856622..4857470) 1 NC_013008.1 hypothetical protein 4857470 8219436 ECSP_4870 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080651.1 4856622 R 544404 CDS YP_003080652.1 254795815 8219438 complement(4857828..4858214) 1 NC_013008.1 hypothetical protein 4858214 8219438 ECSP_4872 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080652.1 4857828 R 544404 CDS YP_003080653.1 254795816 8219439 4858430..4858729 1 NC_013008.1 hypothetical protein 4858729 8219439 ECSP_4873 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080653.1 4858430 D 544404 CDS YP_003080654.1 254795817 8219440 complement(4858776..4859663) 1 NC_013008.1 chloramphenical resistance permease 4859663 rarD 8219440 rarD Escherichia coli O157:H7 str. TW14359 chloramphenical resistance permease YP_003080654.1 4858776 R 544404 CDS YP_003080655.1 254795818 8219441 complement(4859715..4860182) 1 NC_013008.1 hypothetical protein 4860182 yigI 8219441 yigI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080655.1 4859715 R 544404 CDS YP_003080656.1 254795819 8219442 4860347..4861216 1 NC_013008.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4861216 pldA 8219442 pldA Escherichia coli O157:H7 str. TW14359 phospholipase A YP_003080656.1 4860347 D 544404 CDS YP_003080657.1 254795820 8219443 4861349..4863178 1 NC_013008.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4863178 recQ 8219443 recQ Escherichia coli O157:H7 str. TW14359 ATP-dependent DNA helicase RecQ YP_003080657.1 4861349 D 544404 CDS YP_003080658.1 254795821 8219444 4863242..4863862 1 NC_013008.1 threonine efflux system 4863862 rhtC 8219444 rhtC Escherichia coli O157:H7 str. TW14359 threonine efflux system YP_003080658.1 4863242 D 544404 CDS YP_003080659.1 254795822 8219445 complement(4863924..4864544) 1 NC_013008.1 homoserine/homoserine lactone efflux protein 4864544 rhtB 8219445 rhtB Escherichia coli O157:H7 str. TW14359 homoserine/homoserine lactone efflux protein YP_003080659.1 4863924 R 544404 CDS YP_003080660.1 254795823 8219446 4864655..4865677 1 NC_013008.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4865677 pldB 8219446 pldB Escherichia coli O157:H7 str. TW14359 lysophospholipase L2 YP_003080660.1 4864655 D 544404 CDS YP_003080661.1 254795824 8219447 4865685..4866485 1 NC_013008.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4866485 yigL 8219447 yigL Escherichia coli O157:H7 str. TW14359 sugar phosphatase YP_003080661.1 4865685 D 544404 CDS YP_003080662.1 254795825 8219448 4866561..4867460 1 NC_013008.1 inner membrane protein 4867460 yigM 8219448 yigM Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080662.1 4866561 D 544404 CDS YP_003080663.1 254795826 8219449 complement(4867348..4868301) 1 NC_013008.1 DNA-binding transcriptional activator, homocysteine-binding 4868301 metR 8219449 metR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator, homocysteine-binding YP_003080663.1 4867348 R 544404 CDS YP_003080664.1 254795827 8219450 4868537..4870798 1 NC_013008.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4870798 metE 8219450 metE Escherichia coli O157:H7 str. TW14359 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_003080664.1 4868537 D 544404 CDS YP_003080665.1 254795828 8219451 complement(4870838..4871653) 1 NC_013008.1 hydrolase 4871653 ysgA 8219451 ysgA Escherichia coli O157:H7 str. TW14359 hydrolase YP_003080665.1 4870838 R 544404 CDS YP_003080666.1 254795829 8219452 4871915..4872676 1 NC_013008.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4872676 udp 8219452 udp Escherichia coli O157:H7 str. TW14359 uridine phosphorylase YP_003080666.1 4871915 D 544404 CDS YP_003080667.1 254795830 8219453 4872817..4874244 1 NC_013008.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4874244 rmuC 8219453 rmuC Escherichia coli O157:H7 str. TW14359 DNA recombination protein RmuC YP_003080667.1 4872817 D 544404 CDS YP_003080668.1 254795831 8219454 4874339..4875094 1 NC_013008.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4875094 ubiE 8219454 ubiE Escherichia coli O157:H7 str. TW14359 ubiquinone/menaquinone biosynthesis methyltransferase YP_003080668.1 4874339 D 544404 CDS YP_003080669.1 254795832 8219455 4875108..4875713 1 NC_013008.1 hypothetical protein 4875713 yigP 8219455 yigP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080669.1 4875108 D 544404 CDS YP_003080670.1 254795833 8219456 4875710..4877350 1 NC_013008.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4877350 ubiB 8219456 ubiB Escherichia coli O157:H7 str. TW14359 ubiquinone biosynthesis protein UbiB YP_003080670.1 4875710 D 544404 CDS YP_003080671.1 254795834 8219457 4877429..4877698 1 NC_013008.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4877698 tatA 8219457 tatA Escherichia coli O157:H7 str. TW14359 twin arginine translocase protein A YP_003080671.1 4877429 D 544404 CDS YP_003080672.1 254795835 8219458 4877702..4878217 1 NC_013008.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4878217 tatB 8219458 tatB Escherichia coli O157:H7 str. TW14359 sec-independent translocase YP_003080672.1 4877702 D 544404 CDS YP_003080673.1 254795836 8219459 4878220..4878996 1 NC_013008.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4878996 tatC 8219459 tatC Escherichia coli O157:H7 str. TW14359 twin-arginine protein translocation system subunit TatC YP_003080673.1 4878220 D 544404 CDS YP_003080674.1 254795837 8219460 4879038..4879820 1 NC_013008.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4879820 tatD 8219460 tatD Escherichia coli O157:H7 str. TW14359 DNase TatD YP_003080674.1 4879038 D 544404 CDS YP_003080675.1 254795838 8219461 complement(4879817..4880305) 1 NC_013008.1 transcriptional activator RfaH 4880305 rfaH 8219461 rfaH Escherichia coli O157:H7 str. TW14359 transcriptional activator RfaH YP_003080675.1 4879817 R 544404 CDS YP_003080676.1 254795839 8219462 4880472..4881965 1 NC_013008.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4881965 ubiD 8219462 ubiD Escherichia coli O157:H7 str. TW14359 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_003080676.1 4880472 D 544404 CDS YP_003080677.1 254795840 8219463 4882011..4882712 1 NC_013008.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4882712 fre 8219463 fre Escherichia coli O157:H7 str. TW14359 FMN reductase YP_003080677.1 4882011 D 544404 CDS YP_003080678.1 254795841 8219464 complement(4882904..4884067) 1 NC_013008.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4884067 fadA 8219464 fadA Escherichia coli O157:H7 str. TW14359 3-ketoacyl-CoA thiolase YP_003080678.1 4882904 R 544404 CDS YP_003080679.1 254795842 8219465 complement(4884077..4886266) 1 NC_013008.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4886266 fadB 8219465 fadB Escherichia coli O157:H7 str. TW14359 multifunctional fatty acid oxidation complex subunit alpha YP_003080679.1 4884077 R 544404 CDS YP_003080680.1 254795843 8219466 4886456..4887787 1 NC_013008.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4887787 pepQ 8219466 pepQ Escherichia coli O157:H7 str. TW14359 proline dipeptidase YP_003080680.1 4886456 D 544404 CDS YP_003080681.1 254795844 8219467 4887787..4888401 1 NC_013008.1 hypothetical protein 4888401 yigZ 8219467 yigZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080681.1 4887787 D 544404 CDS YP_003080682.1 254795845 8219468 4888440..4889891 1 NC_013008.1 potassium transporter 4889891 trkH 8219468 trkH Escherichia coli O157:H7 str. TW14359 potassium transporter YP_003080682.1 4888440 D 544404 CDS YP_003080683.1 254795846 8219469 4889903..4890448 1 NC_013008.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4890448 hemG 8219469 hemG Escherichia coli O157:H7 str. TW14359 protoporphyrinogen oxidase YP_003080683.1 4889903 D 544404 CDS YP_003080684.1 254795847 8219475 complement(4896033..4896560) 1 NC_013008.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4896560 mobB 8219475 mobB Escherichia coli O157:H7 str. TW14359 molybdopterin-guanine dinucleotide biosynthesis protein B YP_003080684.1 4896033 R 544404 CDS YP_003080685.1 254795848 8219476 complement(4896542..4897126) 1 NC_013008.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4897126 mobA 8219476 mobA Escherichia coli O157:H7 str. TW14359 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_003080685.1 4896542 R 544404 CDS YP_003080686.1 254795849 8219477 4897196..4897465 1 NC_013008.1 hypothetical protein 4897465 yihD 8219477 yihD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080686.1 4897196 D 544404 CDS YP_003080687.1 254795850 8219478 4897542..4898528 1 NC_013008.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4898528 rdoA 8219478 rdoA Escherichia coli O157:H7 str. TW14359 serine/threonine protein kinase YP_003080687.1 4897542 D 544404 CDS YP_003080688.1 254795851 8219479 4898545..4899171 1 NC_013008.1 periplasmic protein disulfide isomerase I 4899171 dsbA 8219479 dsbA Escherichia coli O157:H7 str. TW14359 periplasmic protein disulfide isomerase I YP_003080688.1 4898545 D 544404 CDS YP_003080689.1 254795852 8219480 4899326..4900756 1 NC_013008.1 hypothetical protein 4900756 yihF 8219480 yihF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080689.1 4899326 D 544404 CDS YP_003080690.1 254795853 8219481 complement(4900797..4901729) 1 NC_013008.1 acyltransferase 4901729 yihG 8219481 yihG Escherichia coli O157:H7 str. TW14359 acyltransferase YP_003080690.1 4900797 R 544404 CDS YP_003080691.1 254795854 8219482 4902093..4904879 1 NC_013008.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4904879 polA 8219482 polA Escherichia coli O157:H7 str. TW14359 DNA polymerase I YP_003080691.1 4902093 D 544404 CDS YP_003080692.1 254795855 8219483 complement(4905261..4905893) 1 NC_013008.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4905893 engB 8219483 engB Escherichia coli O157:H7 str. TW14359 ribosome biogenesis GTP-binding protein YsxC YP_003080692.1 4905261 R 544404 CDS YP_003080694.1 254795857 8219485 4906475..4906981 1 NC_013008.1 hypothetical protein 4906981 yihI 8219485 yihI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080694.1 4906475 D 544404 CDS YP_003080695.1 254795858 8219486 4907170..4908543 1 NC_013008.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4908543 hemN 8219486 hemN Escherichia coli O157:H7 str. TW14359 coproporphyrinogen III oxidase YP_003080695.1 4907170 D 544404 CDS YP_003080696.1 254795859 8219487 complement(4908636..4908749) 1 NC_013008.1 hypothetical protein 4908749 8219487 ECSP_4921 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080696.1 4908636 R 544404 CDS YP_003080697.1 254795860 8219488 complement(4908733..4908843) 1 NC_013008.1 hypothetical protein 4908843 8219488 ECSP_4922 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080697.1 4908733 R 544404 CDS YP_003080698.1 254795861 8219489 complement(4908955..4910364) 1 NC_013008.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4910364 glnG 8219489 glnG Escherichia coli O157:H7 str. TW14359 nitrogen regulation protein NR(I) YP_003080698.1 4908955 R 544404 CDS YP_003080699.1 254795862 8219490 complement(4910376..4911425) 1 NC_013008.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4911425 glnL 8219490 glnL Escherichia coli O157:H7 str. TW14359 nitrogen regulation protein NR(II) YP_003080699.1 4910376 R 544404 CDS YP_003080700.1 254795863 8219491 complement(4911599..4913008) 1 NC_013008.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4913008 glnA 8219491 glnA Escherichia coli O157:H7 str. TW14359 glutamine synthetase YP_003080700.1 4911599 R 544404 CDS YP_003080701.1 254795864 8219492 4913381..4915204 1 NC_013008.1 GTP-binding protein 4915204 bipA 8219492 bipA Escherichia coli O157:H7 str. TW14359 GTP-binding protein YP_003080701.1 4913381 D 544404 CDS YP_003080702.1 254795865 8219493 4915421..4916131 1 NC_013008.1 DNA-binding transcriptional regulator 4916131 yihL 8219493 yihL Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080702.1 4915421 D 544404 CDS YP_003080703.1 254795866 8219494 4916139..4917119 1 NC_013008.1 sugar phosphate isomerase 4917119 yihM 8219494 yihM Escherichia coli O157:H7 str. TW14359 sugar phosphate isomerase YP_003080703.1 4916139 D 544404 CDS YP_003080704.1 254795867 8219495 4917221..4918486 1 NC_013008.1 transporter 4918486 yihN 8219495 yihN Escherichia coli O157:H7 str. TW14359 transporter YP_003080704.1 4917221 D 544404 CDS YP_003080705.1 254795868 8219496 complement(4918577..4919269) 1 NC_013008.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L 4919269 ompL 8219496 ompL Escherichia coli O157:H7 str. TW14359 outer membrane porin L YP_003080705.1 4918577 R 544404 CDS YP_003080706.1 254795869 8219497 complement(4919336..4920739) 1 NC_013008.1 predited transporter 4920739 yihO 8219497 yihO Escherichia coli O157:H7 str. TW14359 predited transporter YP_003080706.1 4919336 R 544404 CDS YP_003080707.1 254795870 8219498 complement(4920779..4922164) 1 NC_013008.1 transporter 4922164 yihP 8219498 yihP Escherichia coli O157:H7 str. TW14359 transporter YP_003080707.1 4920779 R 544404 CDS YP_003080708.1 254795871 8219499 complement(4922210..4924246) 1 NC_013008.1 alpha-glucosidase 4924246 yihQ 8219499 yihQ Escherichia coli O157:H7 str. TW14359 alpha-glucosidase YP_003080708.1 4922210 R 544404 CDS YP_003080709.1 254795872 8219500 complement(4924354..4925229) 1 NC_013008.1 hypothetical protein 4925229 8219500 ECSP_4934 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080709.1 4924354 R 544404 CDS YP_003080710.1 254795873 8219501 complement(4925290..4926192) 1 NC_013008.1 aldose-1-epimerase 4926192 yihR 8219501 yihR Escherichia coli O157:H7 str. TW14359 aldose-1-epimerase YP_003080710.1 4925290 R 544404 CDS YP_003080711.1 254795874 8219502 complement(4926259..4927500) 1 NC_013008.1 glucosamine isomerase 4927500 yihS 8219502 yihS Escherichia coli O157:H7 str. TW14359 glucosamine isomerase YP_003080711.1 4926259 R 544404 CDS YP_003080712.1 254795875 8219503 complement(4927516..4928394) 1 NC_013008.1 aldolase 4928394 yihT 8219503 yihT Escherichia coli O157:H7 str. TW14359 aldolase YP_003080712.1 4927516 R 544404 CDS YP_003080713.1 254795876 8219504 complement(4928418..4929314) 1 NC_013008.1 oxidoreductase 4929314 yihU 8219504 yihU Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003080713.1 4928418 R 544404 CDS YP_003080714.1 254795877 8219505 4929482..4930378 1 NC_013008.1 sugar kinase 4930378 yihV 8219505 yihV Escherichia coli O157:H7 str. TW14359 sugar kinase YP_003080714.1 4929482 D 544404 CDS YP_003080715.1 254795878 8219506 4930412..4931197 1 NC_013008.1 DNA-binding transcriptional regulator 4931197 yihW 8219506 yihW Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080715.1 4930412 D 544404 CDS YP_003080716.1 254795879 8219507 4931296..4931895 1 NC_013008.1 phosphatase 4931895 yihX 8219507 yihX Escherichia coli O157:H7 str. TW14359 phosphatase YP_003080716.1 4931296 D 544404 CDS YP_003080717.1 254795880 8219508 4931889..4932761 1 NC_013008.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4932761 rbn 8219508 rbn Escherichia coli O157:H7 str. TW14359 ribonuclease BN YP_003080717.1 4931889 D 544404 CDS YP_003080718.1 254795881 8219509 4932758..4933195 1 NC_013008.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4933195 dtd 8219509 dtd Escherichia coli O157:H7 str. TW14359 D-tyrosyl-tRNA(Tyr) deacylase YP_003080718.1 4932758 D 544404 CDS YP_003080719.1 254795882 8219510 4933192..4934181 1 NC_013008.1 acetyltransferase 4934181 yiiD 8219510 yiiD Escherichia coli O157:H7 str. TW14359 acetyltransferase YP_003080719.1 4933192 D 544404 CDS YP_003080720.1 254795883 8219512 complement(4936799..4936915) 1 NC_013008.1 hypothetical protein 4936915 8219512 ECSP_4946 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080720.1 4936799 R 544404 CDS YP_003080721.1 254795884 8219513 4937100..4937318 1 NC_013008.1 transcriptional regulator 4937318 yiiE 8219513 yiiE Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003080721.1 4937100 D 544404 CDS YP_003080722.1 254795885 8219514 4937559..4937777 1 NC_013008.1 hypothetical protein 4937777 yiiF 8219514 yiiF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080722.1 4937559 D 544404 CDS YP_003080723.1 254795886 8219515 complement(4938107..4939036) 1 NC_013008.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4939036 fdhE 8219515 fdhE Escherichia coli O157:H7 str. TW14359 formate dehydrogenase accessory protein FdhE YP_003080723.1 4938107 R 544404 CDS YP_003080724.1 254795887 8219516 complement(4939033..4939668) 1 NC_013008.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4939668 fdoI 8219516 fdoI Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-O subunit gamma YP_003080724.1 4939033 R 544404 CDS YP_003080725.1 254795888 8219517 complement(4939665..4940567) 1 NC_013008.1 formate dehydrogenase-O, Fe-S subunit 4940567 fdoH 8219517 fdoH Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-O, Fe-S subunit YP_003080725.1 4939665 R 544404 CDS YP_003080726.1 254795889 8219518 complement(4940580..4942994) 1 NC_013008.1 formate dehydrogenase-O, large subunit 4942994 fdoG 8219518 fdoG Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-O, large subunit YP_003080726.1 4940580 R 544404 CDS YP_003080727.1 254795890 8219519 complement(4943043..4943630) 1 NC_013008.1 formate dehydrogenase-O, large subunit 4943630 8219519 ECSP_4953 Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-O, large subunit YP_003080727.1 4943043 R 544404 CDS YP_003080728.1 254795891 8219520 4943824..4944657 1 NC_013008.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4944657 fdhD 8219520 fdhD Escherichia coli O157:H7 str. TW14359 formate dehydrogenase accessory protein YP_003080728.1 4943824 D 544404 CDS YP_003080729.1 254795892 8219521 4944707..4944814 1 NC_013008.1 hypothetical protein 4944814 8219521 ECSP_4955 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080729.1 4944707 D 544404 CDS YP_003080730.1 254795893 8219522 4944811..4945866 1 NC_013008.1 hypothetical protein 4945866 yiiG 8219522 yiiG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080730.1 4944811 D 544404 CDS YP_003080731.1 254795894 8219523 complement(4945916..4947664) 1 NC_013008.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein 4947664 frvR 8219523 frvR Escherichia coli O157:H7 str. TW14359 frv operon regulatory protein YP_003080731.1 4945916 R 544404 CDS YP_003080732.1 254795895 8219524 complement(4947664..4948734) 1 NC_013008.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX 4948734 frvX 8219524 frvX Escherichia coli O157:H7 str. TW14359 fructose-specific phosphotransferase system protein FrvX YP_003080732.1 4947664 R 544404 CDS YP_003080733.1 254795896 8219525 complement(4948724..4950163) 1 NC_013008.1 PTS system transporter subunits IIBC 4950163 frvB 8219525 frvB Escherichia coli O157:H7 str. TW14359 PTS system transporter subunits IIBC YP_003080733.1 4948724 R 544404 CDS YP_003080734.1 254795897 8219526 complement(4950174..4950620) 1 NC_013008.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA 4950620 frvA 8219526 frvA Escherichia coli O157:H7 str. TW14359 fructose-like phosphotransferase system subunit EIIA YP_003080734.1 4950174 R 544404 CDS YP_003080735.1 254795898 8219527 4951098..4952492 1 NC_013008.1 glycoporin 4952492 8219527 ECSP_4961 Escherichia coli O157:H7 str. TW14359 glycoporin YP_003080735.1 4951098 D 544404 CDS YP_003080736.1 254795899 8219528 complement(4952533..4952847) 1 NC_013008.1 L-rhamnose mutarotase 4952847 rhaM 8219528 rhaM Escherichia coli O157:H7 str. TW14359 L-rhamnose mutarotase YP_003080736.1 4952533 R 544404 CDS YP_003080737.1 254795900 8219529 complement(4952857..4953681) 1 NC_013008.1 rhamnulose-1-phosphate aldolase 4953681 rhaD 8219529 rhaD Escherichia coli O157:H7 str. TW14359 rhamnulose-1-phosphate aldolase YP_003080737.1 4952857 R 544404 CDS YP_003080738.1 254795901 8219530 complement(4953856..4955115) 1 NC_013008.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4955115 rhaA 8219530 rhaA Escherichia coli O157:H7 str. TW14359 L-rhamnose isomerase YP_003080738.1 4953856 R 544404 CDS YP_003080739.1 254795902 8219531 complement(4955112..4956581) 1 NC_013008.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4956581 rhaB 8219531 rhaB Escherichia coli O157:H7 str. TW14359 rhamnulokinase YP_003080739.1 4955112 R 544404 CDS YP_003080740.1 254795903 8219532 4956660..4956809 1 NC_013008.1 hypothetical protein 4956809 8219532 ECSP_4966 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080740.1 4956660 D 544404 CDS YP_003080741.1 254795904 8219533 4956869..4957705 1 NC_013008.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4957705 rhaS 8219533 rhaS Escherichia coli O157:H7 str. TW14359 transcriptional activator RhaS YP_003080741.1 4956869 D 544404 CDS YP_003080742.1 254795905 8219534 4957779..4958627 1 NC_013008.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4958627 rhaR 8219534 rhaR Escherichia coli O157:H7 str. TW14359 transcriptional activator RhaR YP_003080742.1 4957779 D 544404 CDS YP_003080743.1 254795906 8219535 complement(4958624..4959415) 1 NC_013008.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4959415 rhaT 8219535 rhaT Escherichia coli O157:H7 str. TW14359 rhamnose-proton symporter YP_003080743.1 4958624 R 544404 CDS YP_003080744.1 254795907 8219536 complement(4959506..4959658) 1 NC_013008.1 hypothetical protein 4959658 8219536 ECSP_4970 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080744.1 4959506 R 544404 CDS YP_003080745.1 254795908 8219537 4959943..4960563 1 NC_013008.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4960563 sodA 8219537 sodA Escherichia coli O157:H7 str. TW14359 superoxide dismutase YP_003080745.1 4959943 D 544404 CDS YP_003080746.1 254795909 8219538 4960823..4961806 1 NC_013008.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4961806 kdgT 8219538 kdgT Escherichia coli O157:H7 str. TW14359 2-keto-3-deoxygluconate permease YP_003080746.1 4960823 D 544404 CDS YP_003080747.1 254795910 8219539 4961955..4962629 1 NC_013008.1 hypothetical protein 4962629 yiiM 8219539 yiiM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080747.1 4961955 D 544404 CDS YP_003080748.1 254795911 8219540 complement(4962735..4964108) 1 NC_013008.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4964108 cpxA 8219540 cpxA Escherichia coli O157:H7 str. TW14359 two-component sensor protein YP_003080748.1 4962735 R 544404 CDS YP_003080749.1 254795912 8219541 complement(4964105..4964803) 1 NC_013008.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4964803 cpxR 8219541 cpxR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator CpxR YP_003080749.1 4964105 R 544404 CDS YP_003080750.1 254795913 8219542 4964953..4965453 1 NC_013008.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4965453 cpxP 8219542 cpxP Escherichia coli O157:H7 str. TW14359 periplasmic repressor CpxP YP_003080750.1 4964953 D 544404 CDS YP_003080751.1 254795914 8219543 4965602..4966504 1 NC_013008.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4966504 fieF 8219543 fieF Escherichia coli O157:H7 str. TW14359 ferrous iron efflux protein F YP_003080751.1 4965602 D 544404 CDS YP_003080752.1 254795915 8219544 4966685..4967647 1 NC_013008.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4967647 pfkA 8219544 pfkA Escherichia coli O157:H7 str. TW14359 6-phosphofructokinase YP_003080752.1 4966685 D 544404 CDS YP_003080753.1 254795916 8219545 complement(4967756..4967938) 1 NC_013008.1 hypothetical protein 4967938 8219545 ECSP_4979 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080753.1 4967756 R 544404 CDS YP_003080754.1 254795917 8219546 4967966..4968955 1 NC_013008.1 sulfate transporter subunit 4968955 sbp 8219546 sbp Escherichia coli O157:H7 str. TW14359 sulfate transporter subunit YP_003080754.1 4967966 D 544404 CDS YP_003080755.1 254795918 8219547 4969062..4969817 1 NC_013008.1 CDP-diacylglycerol pyrophosphatase 4969817 cdh 8219547 cdh Escherichia coli O157:H7 str. TW14359 CDP-diacylglycerol pyrophosphatase YP_003080755.1 4969062 D 544404 CDS YP_003080756.1 254795919 8219548 complement(4969872..4970639) 1 NC_013008.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4970639 tpiA 8219548 tpiA Escherichia coli O157:H7 str. TW14359 triosephosphate isomerase YP_003080756.1 4969872 R 544404 CDS YP_003080757.1 254795920 8219549 complement(4970747..4971346) 1 NC_013008.1 hypothetical protein 4971346 yiiQ 8219549 yiiQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080757.1 4970747 R 544404 CDS YP_003080758.1 254795921 8219550 4971447..4971887 1 NC_013008.1 hypothetical protein 4971887 yiiR 8219550 yiiR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080758.1 4971447 D 544404 CDS YP_003080759.1 254795922 8219551 4972099..4972398 1 NC_013008.1 hypothetical protein 4972398 yiiS 8219551 yiiS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080759.1 4972099 D 544404 CDS YP_003080760.1 254795923 8219552 4972425..4972853 1 NC_013008.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4972853 yiiT 8219552 yiiT Escherichia coli O157:H7 str. TW14359 universal stress protein UspD YP_003080760.1 4972425 D 544404 CDS YP_003080761.1 254795924 8219553 complement(4972858..4973604) 1 NC_013008.1 ferredoxin-NADP reductase 4973604 fpr 8219553 fpr Escherichia coli O157:H7 str. TW14359 ferredoxin-NADP reductase YP_003080761.1 4972858 R 544404 CDS YP_003080762.1 254795925 8219554 complement(4973701..4974711) 1 NC_013008.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4974711 glpX 8219554 glpX Escherichia coli O157:H7 str. TW14359 fructose 1,6-bisphosphatase II YP_003080762.1 4973701 R 544404 CDS YP_003080763.1 254795926 8219555 complement(4974941..4976449) 1 NC_013008.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4976449 glpK 8219555 glpK Escherichia coli O157:H7 str. TW14359 glycerol kinase YP_003080763.1 4974941 R 544404 CDS YP_003080764.1 254795927 8219556 complement(4976472..4977317) 1 NC_013008.1 glycerol facilitator 4977317 glpF 8219556 glpF Escherichia coli O157:H7 str. TW14359 glycerol facilitator YP_003080764.1 4976472 R 544404 CDS YP_003080765.1 254795928 8219557 4977743..4977988 1 NC_013008.1 hypothetical protein 4977988 yiiU 8219557 yiiU Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080765.1 4977743 D 544404 CDS YP_003080766.1 254795929 8219558 complement(4978027..4978743) 1 NC_013008.1 hypothetical protein 4978743 8219558 ECSP_4992 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080766.1 4978027 R 544404 CDS YP_003080767.1 254795930 8219559 complement(4978776..4979450) 1 NC_013008.1 hypothetical protein 4979450 8219559 ECSP_4993 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080767.1 4978776 R 544404 CDS YP_003080768.1 254795931 8219560 complement(4979510..4979995) 1 NC_013008.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4979995 rraA 8219560 rraA Escherichia coli O157:H7 str. TW14359 ribonuclease activity regulator protein RraA YP_003080768.1 4979510 R 544404 CDS YP_003080769.1 254795932 8219561 complement(4980088..4981014) 1 NC_013008.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4981014 menA 8219561 menA Escherichia coli O157:H7 str. TW14359 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_003080769.1 4980088 R 544404 CDS YP_003080770.1 254795933 8219562 complement(4981081..4982412) 1 NC_013008.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4982412 hslU 8219562 hslU Escherichia coli O157:H7 str. TW14359 ATP-dependent protease ATP-binding subunit HslU YP_003080770.1 4981081 R 544404 CDS YP_003080771.1 254795934 8219563 complement(4982422..4982952) 1 NC_013008.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4982952 hslV 8219563 hslV Escherichia coli O157:H7 str. TW14359 ATP-dependent protease peptidase subunit YP_003080771.1 4982422 R 544404 CDS YP_003080772.1 254795935 8219564 complement(4983045..4984004) 1 NC_013008.1 essential cell division protein FtsN 4984004 ftsN 8219564 ftsN Escherichia coli O157:H7 str. TW14359 essential cell division protein FtsN YP_003080772.1 4983045 R 544404 CDS YP_003080773.1 254795936 8219565 complement(4984096..4985121) 1 NC_013008.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4985121 cytR 8219565 cytR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator CytR YP_003080773.1 4984096 R 544404 CDS YP_003080774.1 254795937 8219566 complement(4985277..4987475) 1 NC_013008.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4987475 priA 8219566 priA Escherichia coli O157:H7 str. TW14359 primosome assembly protein PriA YP_003080774.1 4985277 R 544404 CDS YP_003080775.1 254795938 8219567 4987678..4987890 1 NC_013008.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4987890 rpmE 8219567 rpmE Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L31 YP_003080775.1 4987678 D 544404 CDS YP_003080776.1 254795939 8219568 4989277..4992234 1 NC_013008.1 hypothetical protein 4992234 8219568 ECSP_5002 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080776.1 4989277 D 544404 CDS YP_003080777.1 254795940 8219569 4992236..4992472 1 NC_013008.1 hypothetical protein 4992472 8219569 ECSP_5003 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080777.1 4992236 D 544404 CDS YP_003080778.1 254795941 8219570 4992525..4992803 1 NC_013008.1 hypothetical protein 4992803 8219570 ECSP_5004 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080778.1 4992525 D 544404 CDS YP_003080779.1 254795942 8219572 complement(4993048..4993320) 1 NC_013008.1 IS1 insertion element protein 4993320 8219572 ECSP_5006 Escherichia coli O157:H7 str. TW14359 IS1 insertion element protein YP_003080779.1 4993048 R 544404 CDS YP_003080780.1 254795943 8219573 complement(4993465..4994073) 1 NC_013008.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 4994073 yiiX 8219573 yiiX Escherichia coli O157:H7 str. TW14359 peptidoglycan peptidase YP_003080780.1 4993465 R 544404 CDS YP_003080781.1 254795944 8219574 complement(4994133..4994450) 1 NC_013008.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4994450 metJ 8219574 metJ Escherichia coli O157:H7 str. TW14359 transcriptional repressor protein MetJ YP_003080781.1 4994133 R 544404 CDS YP_003080782.1 254795945 8219575 4994727..4995887 1 NC_013008.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4995887 metB 8219575 metB Escherichia coli O157:H7 str. TW14359 cystathionine gamma-synthase YP_003080782.1 4994727 D 544404 CDS YP_003080783.1 254795946 8219576 4995890..4998322 1 NC_013008.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4998322 metL 8219576 metL Escherichia coli O157:H7 str. TW14359 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_003080783.1 4995890 D 544404 CDS YP_003080784.1 254795947 8219577 4998671..4999561 1 NC_013008.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4999561 metF 8219577 metF Escherichia coli O157:H7 str. TW14359 5,10-methylenetetrahydrofolate reductase YP_003080784.1 4998671 D 544404 CDS YP_003080785.1 254795948 8219578 4999890..5002070 1 NC_013008.1 catalase/hydroperoxidase HPI(I) 5002070 katG 8219578 katG Escherichia coli O157:H7 str. TW14359 catalase/hydroperoxidase HPI(I) YP_003080785.1 4999890 D 544404 CDS YP_003080786.1 254795949 8219579 5002164..5003069 1 NC_013008.1 permease 5003069 yijE 8219579 yijE Escherichia coli O157:H7 str. TW14359 permease YP_003080786.1 5002164 D 544404 CDS YP_003080787.1 254795950 8219580 complement(5003096..5003713) 1 NC_013008.1 hypothetical protein 5003713 yijF 8219580 yijF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080787.1 5003096 R 544404 CDS YP_003080788.1 254795951 8219581 complement(5003987..5005090) 1 NC_013008.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 5005090 gldA 8219581 gldA Escherichia coli O157:H7 str. TW14359 glycerol dehydrogenase YP_003080788.1 5003987 R 544404 CDS YP_003080789.1 254795952 8219582 complement(5005101..5005763) 1 NC_013008.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 5005763 fsaB 8219582 fsaB Escherichia coli O157:H7 str. TW14359 fructose-6-phosphate aldolase YP_003080789.1 5005101 R 544404 CDS YP_003080790.1 254795953 8219583 complement(5005775..5008276) 1 NC_013008.1 fused PTS enzymes: Hpr component, enzyme I component, enzyme IIA component 5008276 ptsA 8219583 ptsA Escherichia coli O157:H7 str. TW14359 fused PTS enzymes: Hpr component, enzyme I component, enzyme IIA component YP_003080790.1 5005775 R 544404 CDS YP_003080791.1 254795954 8219584 5008585..5009664 1 NC_013008.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 5009664 8219584 ECSP_5018 Escherichia coli O157:H7 str. TW14359 fructose-like permease EIIC subunit 2 YP_003080791.1 5008585 D 544404 CDS YP_003080792.1 254795955 8219585 5009679..5009999 1 NC_013008.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 5009999 frwB 8219585 frwB Escherichia coli O157:H7 str. TW14359 PTS system fructose-like transporter subunit EIIB YP_003080792.1 5009679 D 544404 CDS YP_003080793.1 254795956 8219586 5010050..5012347 1 NC_013008.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 5012347 pflD 8219586 pflD Escherichia coli O157:H7 str. TW14359 formate acetyltransferase 2 YP_003080793.1 5010050 D 544404 CDS YP_003080794.1 254795957 8219587 5012313..5013191 1 NC_013008.1 pyruvate formate lyase II activase 5013191 pflC 8219587 pflC Escherichia coli O157:H7 str. TW14359 pyruvate formate lyase II activase YP_003080794.1 5012313 D 544404 CDS YP_003080795.1 254795958 8219588 5013193..5013534 1 NC_013008.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 5013534 frwD 8219588 frwD Escherichia coli O157:H7 str. TW14359 fructose-like phosphotransferase EIIB subunit 3 YP_003080795.1 5013193 D 544404 CDS YP_003080796.1 254795959 8219589 complement(5013521..5014372) 1 NC_013008.1 DNA-binding transcriptional regulator 5014372 yijO 8219589 yijO Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003080796.1 5013521 R 544404 CDS YP_003080797.1 254795960 8219590 complement(5014587..5016320) 1 NC_013008.1 hypothetical protein 5016320 yijP 8219590 yijP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080797.1 5014587 R 544404 CDS YP_003080798.1 254795961 8219591 complement(5016503..5019154) 1 NC_013008.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 5019154 ppc 8219591 ppc Escherichia coli O157:H7 str. TW14359 phosphoenolpyruvate carboxylase YP_003080798.1 5016503 R 544404 CDS YP_003080799.1 254795962 8219592 complement(5019506..5020657) 1 NC_013008.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 5020657 argE 8219592 argE Escherichia coli O157:H7 str. TW14359 acetylornithine deacetylase YP_003080799.1 5019506 R 544404 CDS YP_003080800.1 254795963 8219593 5020811..5021815 1 NC_013008.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 5021815 argC 8219593 argC Escherichia coli O157:H7 str. TW14359 N-acetyl-gamma-glutamyl-phosphate reductase YP_003080800.1 5020811 D 544404 CDS YP_003080801.1 254795964 8219594 5021823..5022599 1 NC_013008.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 5022599 argB 8219594 argB Escherichia coli O157:H7 str. TW14359 acetylglutamate kinase YP_003080801.1 5021823 D 544404 CDS YP_003080802.1 254795965 8219595 5022660..5024033 1 NC_013008.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 5024033 argH 8219595 argH Escherichia coli O157:H7 str. TW14359 argininosuccinate lyase YP_003080802.1 5022660 D 544404 CDS YP_003080803.1 254795966 8219596 5024300..5025217 1 NC_013008.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 5025217 oxyR 8219596 oxyR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator OxyR YP_003080803.1 5024300 D 544404 CDS YP_003080804.1 254795967 8219597 complement(5025200..5026600) 1 NC_013008.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 5026600 sthA 8219597 sthA Escherichia coli O157:H7 str. TW14359 soluble pyridine nucleotide transhydrogenase YP_003080804.1 5025200 R 544404 CDS YP_003080805.1 254795968 8219598 5026930..5028096 1 NC_013008.1 hippuricase 5028096 8219598 ECSP_5032 Escherichia coli O157:H7 str. TW14359 hippuricase YP_003080805.1 5026930 D 544404 CDS YP_003080806.1 254795969 8219599 5028139..5029455 1 NC_013008.1 citrate permease 5029455 8219599 ECSP_5033 Escherichia coli O157:H7 str. TW14359 citrate permease YP_003080806.1 5028139 D 544404 CDS YP_003080807.1 254795970 8219600 5029562..5030209 1 NC_013008.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 5030209 fabR 8219600 fabR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor FabR YP_003080807.1 5029562 D 544404 CDS YP_003080808.1 254795971 8219601 5030209..5030568 1 NC_013008.1 hypothetical protein 5030568 yijD 8219601 yijD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080808.1 5030209 D 544404 CDS YP_003080809.1 254795972 8219602 complement(5030608..5031708) 1 NC_013008.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 5031708 trmA 8219602 trmA Escherichia coli O157:H7 str. TW14359 tRNA (uracil-5-)-methyltransferase YP_003080809.1 5030608 R 544404 CDS YP_003080810.1 254795973 8219603 5032077..5033921 1 NC_013008.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 5033921 btuB 8219603 btuB Escherichia coli O157:H7 str. TW14359 vitamin B12/cobalamin outer membrane transporter YP_003080810.1 5032077 D 544404 CDS YP_003080811.1 254795974 8219604 5033866..5034723 1 NC_013008.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 5034723 murI 8219604 murI Escherichia coli O157:H7 str. TW14359 glutamate racemase YP_003080811.1 5033866 D 544404 CDS YP_003080812.1 254795975 8219609 5040247..5041275 1 NC_013008.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 5041275 murB 8219609 murB Escherichia coli O157:H7 str. TW14359 UDP-N-acetylenolpyruvoylglucosamine reductase YP_003080812.1 5040247 D 544404 CDS YP_003080813.1 254795976 8219610 5041272..5042237 1 NC_013008.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 5042237 birA 8219610 birA Escherichia coli O157:H7 str. TW14359 biotin--protein ligase YP_003080813.1 5041272 D 544404 CDS YP_003080814.1 254795977 8219611 complement(5042266..5043192) 1 NC_013008.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 5043192 coaA 8219611 coaA Escherichia coli O157:H7 str. TW14359 pantothenate kinase YP_003080814.1 5042266 R 544404 CDS YP_003080815.1 254795978 8219616 5044134..5045318 1 NC_013008.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 5045318 tufB 8219616 tufB Escherichia coli O157:H7 str. TW14359 elongation factor Tu YP_003080815.1 5044134 D 544404 CDS YP_003080816.1 254795979 8219617 5045548..5045931 1 NC_013008.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 5045931 secE 8219617 secE Escherichia coli O157:H7 str. TW14359 preprotein translocase subunit SecE YP_003080816.1 5045548 D 544404 CDS YP_003080817.1 254795980 8219618 5045933..5046478 1 NC_013008.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 5046478 nusG 8219618 nusG Escherichia coli O157:H7 str. TW14359 transcription antitermination protein NusG YP_003080817.1 5045933 D 544404 CDS YP_003080818.1 254795981 8219619 5046637..5047065 1 NC_013008.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 5047065 rplK 8219619 rplK Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L11 YP_003080818.1 5046637 D 544404 CDS YP_003080819.1 254795982 8219620 5047069..5047773 1 NC_013008.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 5047773 rplA 8219620 rplA Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L1 YP_003080819.1 5047069 D 544404 CDS YP_003080820.1 254795983 8219621 5048065..5048562 1 NC_013008.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 5048562 rplJ 8219621 rplJ Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L10 YP_003080820.1 5048065 D 544404 CDS YP_003080821.1 254795984 8219622 5048629..5048994 1 NC_013008.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 5048994 rplL 8219622 rplL Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L7/L12 YP_003080821.1 5048629 D 544404 CDS YP_003080822.1 254795985 8219623 5049314..5053342 1 NC_013008.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 5053342 rpoB 8219623 rpoB Escherichia coli O157:H7 str. TW14359 DNA-directed RNA polymerase subunit beta YP_003080822.1 5049314 D 544404 CDS YP_003080823.1 254795986 8219624 5053419..5057642 1 NC_013008.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 5057642 rpoC 8219624 rpoC Escherichia coli O157:H7 str. TW14359 DNA-directed RNA polymerase subunit beta' YP_003080823.1 5053419 D 544404 CDS YP_003080824.1 254795987 8219625 5057855..5058298 1 NC_013008.1 heat shock protein 5058298 htrC 8219625 htrC Escherichia coli O157:H7 str. TW14359 heat shock protein YP_003080824.1 5057855 D 544404 CDS YP_003080825.1 254795988 8219626 complement(5058733..5059866) 1 NC_013008.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 5059866 thiH 8219626 thiH Escherichia coli O157:H7 str. TW14359 thiamine biosynthesis protein ThiH YP_003080825.1 5058733 R 544404 CDS YP_003080826.1 254795989 8219627 complement(5059863..5060633) 1 NC_013008.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 5060633 thiG 8219627 thiG Escherichia coli O157:H7 str. TW14359 thiazole synthase YP_003080826.1 5059863 R 544404 CDS YP_003080827.1 254795990 8219628 complement(5060819..5061574) 1 NC_013008.1 thiamin (thiazole moiety) biosynthesis protein 5061574 thiF 8219628 thiF Escherichia coli O157:H7 str. TW14359 thiamin (thiazole moiety) biosynthesis protein YP_003080827.1 5060819 R 544404 CDS YP_003080828.1 254795991 8219629 complement(5061567..5062202) 1 NC_013008.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 5062202 thiE 8219629 thiE Escherichia coli O157:H7 str. TW14359 thiamine-phosphate pyrophosphorylase YP_003080828.1 5061567 R 544404 CDS YP_003080829.1 254795992 8219630 complement(5062202..5064097) 1 NC_013008.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 5064097 thiC 8219630 thiC Escherichia coli O157:H7 str. TW14359 thiamine biosynthesis protein ThiC YP_003080829.1 5062202 R 544404 CDS YP_003080830.1 254795993 8219631 complement(5064330..5064806) 1 NC_013008.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 5064806 rsd 8219631 rsd Escherichia coli O157:H7 str. TW14359 anti-RNA polymerase sigma 70 factor YP_003080830.1 5064330 R 544404 CDS YP_003080831.1 254795994 8219632 5064901..5065674 1 NC_013008.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 5065674 nudC 8219632 nudC Escherichia coli O157:H7 str. TW14359 NADH pyrophosphatase YP_003080831.1 5064901 D 544404 CDS YP_003080832.1 254795995 8219633 5065714..5066778 1 NC_013008.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 5066778 hemE 8219633 hemE Escherichia coli O157:H7 str. TW14359 uroporphyrinogen decarboxylase YP_003080832.1 5065714 D 544404 CDS YP_003080833.1 254795996 8219634 5066788..5067459 1 NC_013008.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 5067459 nfi 8219634 nfi Escherichia coli O157:H7 str. TW14359 endonuclease V YP_003080833.1 5066788 D 544404 CDS YP_003080834.1 254795997 8219635 5067502..5068092 1 NC_013008.1 hypothetical protein 5068092 yjaG 8219635 yjaG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080834.1 5067502 D 544404 CDS YP_003080835.1 254795998 8219636 5068279..5068551 1 NC_013008.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 5068551 hupA 8219636 hupA Escherichia coli O157:H7 str. TW14359 transcriptional regulator HU subunit alpha YP_003080835.1 5068279 D 544404 CDS YP_003080836.1 254795999 8219637 5068564..5069259 1 NC_013008.1 hypothetical protein 5069259 yjaH 8219637 yjaH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080836.1 5068564 D 544404 CDS YP_003080837.1 254796000 8219638 complement(5069261..5069686) 1 NC_013008.1 zinc resistance protein 5069686 zraP 8219638 zraP Escherichia coli O157:H7 str. TW14359 zinc resistance protein YP_003080837.1 5069261 R 544404 CDS YP_003080838.1 254796001 8219639 5069924..5071300 1 NC_013008.1 sensor protein ZraS 5071300 zraS 8219639 zraS Escherichia coli O157:H7 str. TW14359 sensor protein ZraS YP_003080838.1 5069924 D 544404 CDS YP_003080839.1 254796002 8219640 5071297..5072622 1 NC_013008.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 5072622 zraR 8219640 zraR Escherichia coli O157:H7 str. TW14359 transcriptional regulatory protein ZraR YP_003080839.1 5071297 D 544404 CDS YP_003080840.1 254796003 8219641 complement(5072619..5073908) 1 NC_013008.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 5073908 purD 8219641 purD Escherichia coli O157:H7 str. TW14359 phosphoribosylamine--glycine ligase YP_003080840.1 5072619 R 544404 CDS YP_003080841.1 254796004 8219642 complement(5073920..5075509) 1 NC_013008.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5075509 purH 8219642 purH Escherichia coli O157:H7 str. TW14359 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_003080841.1 5073920 R 544404 CDS YP_003080842.1 254796005 8219647 complement(5081253..5081696) 1 NC_013008.1 hypothetical protein 5081696 yjaB 8219647 yjaB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080842.1 5081253 R 544404 CDS YP_003080843.1 254796006 8219648 5081853..5082782 1 NC_013008.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 5082782 metA 8219648 metA Escherichia coli O157:H7 str. TW14359 homoserine O-succinyltransferase YP_003080843.1 5081853 D 544404 CDS YP_003080844.1 254796007 8219649 5083051..5084652 1 NC_013008.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 5084652 aceB 8219649 aceB Escherichia coli O157:H7 str. TW14359 malate synthase YP_003080844.1 5083051 D 544404 CDS YP_003080845.1 254796008 8219650 5084682..5085986 1 NC_013008.1 isocitrate lyase 5085986 aceA 8219650 aceA Escherichia coli O157:H7 str. TW14359 isocitrate lyase YP_003080845.1 5084682 D 544404 CDS YP_003080846.1 254796009 8219651 5086170..5087906 1 NC_013008.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 5087906 aceK 8219651 aceK Escherichia coli O157:H7 str. TW14359 bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_003080846.1 5086170 D 544404 CDS YP_003080847.1 254796010 8219652 complement(5087875..5090061) 1 NC_013008.1 non-LEE-encoded type III effector 5090061 espL4 8219652 espL4 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003080847.1 5087875 R 544404 CDS YP_003080848.1 254796011 8219653 complement(5090378..5091202) 1 NC_013008.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR 5091202 iclR 8219653 iclR Escherichia coli O157:H7 str. TW14359 transcriptional repressor IclR YP_003080848.1 5090378 R 544404 CDS YP_003080849.1 254796012 8219654 5091402..5095085 1 NC_013008.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 5095085 metH 8219654 metH Escherichia coli O157:H7 str. TW14359 B12-dependent methionine synthase YP_003080849.1 5091402 D 544404 CDS YP_003080850.1 254796013 8219655 5095305..5096936 1 NC_013008.1 transporter 5096936 yjbB 8219655 yjbB Escherichia coli O157:H7 str. TW14359 transporter YP_003080850.1 5095305 D 544404 CDS YP_003080851.1 254796014 8219656 complement(5097027..5097716) 1 NC_013008.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 5097716 pepE 8219656 pepE Escherichia coli O157:H7 str. TW14359 peptidase E YP_003080851.1 5097027 R 544404 CDS YP_003080852.1 254796015 8219657 complement(5098099..5099328) 1 NC_013008.1 L-sorbose-1-P-reductase 5099328 8219657 ECSP_5091 Escherichia coli O157:H7 str. TW14359 L-sorbose-1-P-reductase YP_003080852.1 5098099 R 544404 CDS YP_003080853.1 254796016 8219658 complement(5099380..5100204) 1 NC_013008.1 sorbose PTS component 5100204 8219658 ECSP_5092 Escherichia coli O157:H7 str. TW14359 sorbose PTS component YP_003080853.1 5099380 R 544404 CDS YP_003080854.1 254796017 8219659 complement(5100215..5101012) 1 NC_013008.1 sorbose PTS component 5101012 8219659 ECSP_5093 Escherichia coli O157:H7 str. TW14359 sorbose PTS component YP_003080854.1 5100215 R 544404 CDS YP_003080855.1 254796018 8219660 complement(5101078..5101572) 1 NC_013008.1 sorbose PTS component 5101572 8219660 ECSP_5094 Escherichia coli O157:H7 str. TW14359 sorbose PTS component YP_003080855.1 5101078 R 544404 CDS YP_003080856.1 254796019 8219661 complement(5101572..5101979) 1 NC_013008.1 sorbose PTS component 5101979 8219661 ECSP_5095 Escherichia coli O157:H7 str. TW14359 sorbose PTS component YP_003080856.1 5101572 R 544404 CDS YP_003080857.1 254796020 8219662 complement(5101989..5102795) 1 NC_013008.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 5102795 8219662 ECSP_5096 Escherichia coli O157:H7 str. TW14359 sorbitol-6-phosphate 2-dehydrogenase YP_003080857.1 5101989 R 544404 CDS YP_003080858.1 254796021 8219663 complement(5102865..5103812) 1 NC_013008.1 transcriptional regulator of sorbose uptake and utilization genes 5103812 8219663 ECSP_5097 Escherichia coli O157:H7 str. TW14359 transcriptional regulator of sorbose uptake and utilization genes YP_003080858.1 5102865 R 544404 CDS YP_003080859.1 254796022 8219664 5104160..5105032 1 NC_013008.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 5105032 rluF 8219664 rluF Escherichia coli O157:H7 str. TW14359 23S rRNA pseudouridine synthase F YP_003080859.1 5104160 D 544404 CDS YP_003080860.1 254796023 8219665 complement(5105033..5105305) 1 NC_013008.1 hypothetical protein 5105305 yjbD 8219665 yjbD Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080860.1 5105033 R 544404 CDS YP_003080861.1 254796024 8219666 complement(5105558..5106907) 1 NC_013008.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 5106907 lysC 8219666 lysC Escherichia coli O157:H7 str. TW14359 aspartate kinase YP_003080861.1 5105558 R 544404 CDS YP_003080862.1 254796025 8219667 5107432..5109081 1 NC_013008.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 5109081 pgi 8219667 pgi Escherichia coli O157:H7 str. TW14359 glucose-6-phosphate isomerase YP_003080862.1 5107432 D 544404 CDS YP_003080863.1 254796026 8219668 5109594..5109836 1 NC_013008.1 hypothetical protein 5109836 yjbE 8219668 yjbE Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080863.1 5109594 D 544404 CDS YP_003080864.1 254796027 8219669 5109950..5110588 1 NC_013008.1 lipoprotein 5110588 yjbF 8219669 yjbF Escherichia coli O157:H7 str. TW14359 lipoprotein YP_003080864.1 5109950 D 544404 CDS YP_003080865.1 254796028 8219670 5110585..5111322 1 NC_013008.1 hypothetical protein 5111322 yjbG 8219670 yjbG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080865.1 5110585 D 544404 CDS YP_003080866.1 254796029 8219671 5111322..5113418 1 NC_013008.1 porin 5113418 yjbH 8219671 yjbH Escherichia coli O157:H7 str. TW14359 porin YP_003080866.1 5111322 D 544404 CDS YP_003080867.1 254796030 8219672 complement(5113465..5113743) 1 NC_013008.1 hypothetical protein 5113743 8219672 ECSP_5106 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080867.1 5113465 R 544404 CDS YP_003080868.1 254796031 8219673 5113744..5113887 1 NC_013008.1 hypothetical protein 5113887 8219673 ECSP_5107 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080868.1 5113744 D 544404 CDS YP_003080869.1 254796032 8219674 5114013..5114423 1 NC_013008.1 phosphate-starvation-inducible protein PsiE 5114423 psiE 8219674 psiE Escherichia coli O157:H7 str. TW14359 phosphate-starvation-inducible protein PsiE YP_003080869.1 5114013 D 544404 CDS YP_003080870.1 254796033 8219675 complement(5114467..5115942) 1 NC_013008.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 5115942 xylE 8219675 xylE Escherichia coli O157:H7 str. TW14359 D-xylose transporter XylE YP_003080870.1 5114467 R 544404 CDS YP_003080871.1 254796034 8219676 complement(5116314..5117204) 1 NC_013008.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 5117204 malG 8219676 malG Escherichia coli O157:H7 str. TW14359 maltose transporter permease YP_003080871.1 5116314 R 544404 CDS YP_003080872.1 254796035 8219677 complement(5117219..5118763) 1 NC_013008.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 5118763 malF 8219677 malF Escherichia coli O157:H7 str. TW14359 maltose transporter membrane protein YP_003080872.1 5117219 R 544404 CDS YP_003080873.1 254796036 8219678 complement(5118917..5120107) 1 NC_013008.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 5120107 malE 8219678 malE Escherichia coli O157:H7 str. TW14359 maltose ABC transporter periplasmic protein YP_003080873.1 5118917 R 544404 CDS YP_003080874.1 254796037 8219679 5120472..5121587 1 NC_013008.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 5121587 malK 8219679 malK Escherichia coli O157:H7 str. TW14359 maltose/maltodextrin transporter ATP-binding protein YP_003080874.1 5120472 D 544404 CDS YP_003080875.1 254796038 8219680 5121659..5122999 1 NC_013008.1 porin involved in the transport of maltose and maltodextrins; maltoporin 5122999 lamB 8219680 lamB Escherichia coli O157:H7 str. TW14359 maltoporin YP_003080875.1 5121659 D 544404 CDS YP_003080876.1 254796039 8219681 5123150..5124070 1 NC_013008.1 maltose regulon periplasmic protein 5124070 malM 8219681 malM Escherichia coli O157:H7 str. TW14359 maltose regulon periplasmic protein YP_003080876.1 5123150 D 544404 CDS YP_003080877.1 254796040 8219682 5124299..5125879 1 NC_013008.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 5125879 espX4 8219682 espX4 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080877.1 5124299 D 544404 CDS YP_003080878.1 254796041 8219683 5126102..5126599 1 NC_013008.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 5126599 ubiC 8219683 ubiC Escherichia coli O157:H7 str. TW14359 chorismate pyruvate lyase YP_003080878.1 5126102 D 544404 CDS YP_003080879.1 254796042 8219684 5126612..5127484 1 NC_013008.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 5127484 ubiA 8219684 ubiA Escherichia coli O157:H7 str. TW14359 4-hydroxybenzoate octaprenyltransferase YP_003080879.1 5126612 D 544404 CDS YP_003080880.1 254796043 8219685 complement(5127639..5130062) 1 NC_013008.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 5130062 plsB 8219685 plsB Escherichia coli O157:H7 str. TW14359 glycerol-3-phosphate acyltransferase YP_003080880.1 5127639 R 544404 CDS YP_003080881.1 254796044 8219686 5130233..5130601 1 NC_013008.1 diacylglycerol kinase 5130601 dgkA 8219686 dgkA Escherichia coli O157:H7 str. TW14359 diacylglycerol kinase YP_003080881.1 5130233 D 544404 CDS YP_003080882.1 254796045 8219687 5130711..5131319 1 NC_013008.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 5131319 lexA 8219687 lexA Escherichia coli O157:H7 str. TW14359 LexA repressor YP_003080882.1 5130711 D 544404 CDS YP_003080883.1 254796046 8219688 5131338..5132717 1 NC_013008.1 DNA-damage-inducible SOS response protein 5132717 dinF 8219688 dinF Escherichia coli O157:H7 str. TW14359 DNA-damage-inducible SOS response protein YP_003080883.1 5131338 D 544404 CDS YP_003080884.1 254796047 8219689 5132833..5133042 1 NC_013008.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 5133042 yjbJ 8219689 yjbJ Escherichia coli O157:H7 str. TW14359 stress-response protein YP_003080884.1 5132833 D 544404 CDS YP_003080885.1 254796048 8219690 complement(5133084..5133599) 1 NC_013008.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 5133599 zur 8219690 zur Escherichia coli O157:H7 str. TW14359 zinc uptake transcriptional repressor YP_003080885.1 5133084 R 544404 CDS YP_003080886.1 254796049 8219691 5133911..5134867 1 NC_013008.1 hypothetical protein 5134867 yjbM 8219691 yjbM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080886.1 5133911 D 544404 CDS YP_003080887.1 254796050 8219692 5135229..5135351 1 NC_013008.1 hypothetical protein 5135351 8219692 ECSP_5126 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080887.1 5135229 D 544404 CDS YP_003080888.1 254796051 8219693 5135480..5136013 1 NC_013008.1 hypothetical protein 5136013 8219693 ECSP_5127 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080888.1 5135480 D 544404 CDS YP_003080889.1 254796052 8219694 5136210..5136383 1 NC_013008.1 hypothetical protein 5136383 8219694 ECSP_5128 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080889.1 5136210 D 544404 CDS YP_003080890.1 254796053 8219695 complement(5136431..5136724) 1 NC_013008.1 hypothetical protein 5136724 8219695 ECSP_5129 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080890.1 5136431 R 544404 CDS YP_003080891.1 254796054 8219696 complement(5136749..5137087) 1 NC_013008.1 endodeoxyribonuclease 5137087 8219696 ECSP_5130 Escherichia coli O157:H7 str. TW14359 endodeoxyribonuclease YP_003080891.1 5136749 R 544404 CDS YP_003080892.1 254796055 8219697 complement(5137057..5137254) 1 NC_013008.1 hypothetical protein 5137254 8219697 ECSP_5131 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080892.1 5137057 R 544404 CDS YP_003080893.1 254796056 8219699 complement(5137871..5138200) 1 NC_013008.1 hypothetical protein 5138200 8219699 ECSP_5133 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080893.1 5137871 R 544404 CDS YP_003080894.1 254796057 8219700 complement(5138212..5138748) 1 NC_013008.1 hypothetical protein 5138748 8219700 ECSP_5134 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080894.1 5138212 R 544404 CDS YP_003080895.1 254796058 8219701 complement(5138876..5139262) 1 NC_013008.1 hypothetical protein 5139262 8219701 ECSP_5135 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080895.1 5138876 R 544404 CDS YP_003080896.1 254796059 8219702 5139349..5140002 1 NC_013008.1 hypothetical protein 5140002 8219702 ECSP_5136 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080896.1 5139349 D 544404 CDS YP_003080897.1 254796060 8219703 5140070..5140669 1 NC_013008.1 Ail/Lom family protein 5140669 8219703 ECSP_5137 Escherichia coli O157:H7 str. TW14359 Ail/Lom family protein YP_003080897.1 5140070 D 544404 CDS YP_003080898.1 254796061 8219704 5140734..5142047 1 NC_013008.1 tail fiber protein 5142047 8219704 ECSP_5138 Escherichia coli O157:H7 str. TW14359 tail fiber protein YP_003080898.1 5140734 D 544404 CDS YP_003080899.1 254796062 8219705 5142049..5142318 1 NC_013008.1 hypothetical protein 5142318 8219705 ECSP_5139 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080899.1 5142049 D 544404 CDS YP_003080900.1 254796063 8219706 5142430..5143002 1 NC_013008.1 hypothetical protein 5143002 8219706 ECSP_5140 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080900.1 5142430 D 544404 CDS YP_003080901.1 254796064 8219707 5143138..5143704 1 NC_013008.1 hypothetical protein 5143704 8219707 ECSP_5141 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080901.1 5143138 D 544404 CDS YP_003080902.1 254796065 8219708 5143786..5144427 1 NC_013008.1 hypothetical protein 5144427 8219708 ECSP_5142 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080902.1 5143786 D 544404 CDS YP_003080903.1 254796066 8219709 complement(5144588..5144836) 1 NC_013008.1 hypothetical protein 5144836 8219709 ECSP_5143 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080903.1 5144588 R 544404 CDS YP_003080904.1 254796067 8219710 complement(5144898..5145995) 1 NC_013008.1 phage integrase family protein 5145995 8219710 ECSP_5144 Escherichia coli O157:H7 str. TW14359 phage integrase family protein YP_003080904.1 5144898 R 544404 CDS YP_003080905.1 254796068 8219711 5146129..5147121 1 NC_013008.1 tRNA-dihydrouridine synthase A 5147121 dusA 8219711 dusA Escherichia coli O157:H7 str. TW14359 tRNA-dihydrouridine synthase A YP_003080905.1 5146129 D 544404 CDS YP_003080906.1 254796069 8219712 5147255..5147497 1 NC_013008.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 5147497 pspG 8219712 pspG Escherichia coli O157:H7 str. TW14359 phage shock protein G YP_003080906.1 5147255 D 544404 CDS YP_003080907.1 254796070 8219713 complement(5147663..5148646) 1 NC_013008.1 quinone oxidoreductase, NADPH-dependent 5148646 qor 8219713 qor Escherichia coli O157:H7 str. TW14359 quinone oxidoreductase, NADPH-dependent YP_003080907.1 5147663 R 544404 CDS YP_003080908.1 254796071 8219714 5148729..5150144 1 NC_013008.1 unwinds double stranded DNA; replicative DNA helicase 5150144 dnaB 8219714 dnaB Escherichia coli O157:H7 str. TW14359 replicative DNA helicase YP_003080908.1 5148729 D 544404 CDS YP_003080909.1 254796072 8219715 5150197..5151276 1 NC_013008.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 5151276 alr 8219715 alr Escherichia coli O157:H7 str. TW14359 alanine racemase YP_003080909.1 5150197 D 544404 CDS YP_003080910.1 254796073 8219716 5151529..5152722 1 NC_013008.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 5152722 tyrB 8219716 tyrB Escherichia coli O157:H7 str. TW14359 aromatic amino acid aminotransferase YP_003080910.1 5151529 D 544404 CDS YP_003080911.1 254796074 8219717 complement(5153061..5153420) 1 NC_013008.1 hypothetical protein 5153420 8219717 ECSP_5151 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080911.1 5153061 R 544404 CDS YP_003080912.1 254796075 8219718 5153821..5154534 1 NC_013008.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 5154534 aphA 8219718 aphA Escherichia coli O157:H7 str. TW14359 acid phosphatase/phosphotransferase YP_003080912.1 5153821 D 544404 CDS YP_003080913.1 254796076 8219719 5154645..5155061 1 NC_013008.1 hypothetical protein 5155061 yjbQ 8219719 yjbQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080913.1 5154645 D 544404 CDS YP_003080914.1 254796077 8219720 5155065..5155421 1 NC_013008.1 hypothetical protein 5155421 yjbR 8219720 yjbR Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080914.1 5155065 D 544404 CDS YP_003080915.1 254796078 8219721 complement(5155456..5158278) 1 NC_013008.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 5158278 uvrA 8219721 uvrA Escherichia coli O157:H7 str. TW14359 excinuclease ABC subunit A YP_003080915.1 5155456 R 544404 CDS YP_003080916.1 254796079 8219722 5158533..5159069 1 NC_013008.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 5159069 8219722 ECSP_5156 Escherichia coli O157:H7 str. TW14359 single-stranded DNA-binding protein YP_003080916.1 5158533 D 544404 CDS YP_003080917.1 254796080 8219723 complement(5159168..5159449) 1 NC_013008.1 inner membrane protein 5159449 yjcB 8219723 yjcB Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003080917.1 5159168 R 544404 CDS YP_003080918.1 254796081 8219724 5159878..5161464 1 NC_013008.1 signal transduction protein 5161464 yjcC 8219724 yjcC Escherichia coli O157:H7 str. TW14359 signal transduction protein YP_003080918.1 5159878 D 544404 CDS YP_003080919.1 254796082 8219725 complement(5161467..5161790) 1 NC_013008.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 5161790 soxS 8219725 soxS Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator SoxS YP_003080919.1 5161467 R 544404 CDS YP_003080920.1 254796083 8219726 5161876..5162340 1 NC_013008.1 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 5162340 soxR 8219726 soxR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing YP_003080920.1 5161876 D 544404 CDS YP_003080921.1 254796084 8219727 5162886..5164235 1 NC_013008.1 permease 5164235 yjcD 8219727 yjcD Escherichia coli O157:H7 str. TW14359 permease YP_003080921.1 5162886 D 544404 CDS YP_003080922.1 254796085 8219728 5164386..5166035 1 NC_013008.1 cation/proton antiporter 5166035 yjcE 8219728 yjcE Escherichia coli O157:H7 str. TW14359 cation/proton antiporter YP_003080922.1 5164386 D 544404 CDS YP_003080923.1 254796086 8219729 complement(5166189..5167481) 1 NC_013008.1 non-LEE-encoded type III effector 5167481 espX5 8219729 espX5 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003080923.1 5166189 R 544404 CDS YP_003080924.1 254796087 8219730 complement(5167662..5169311) 1 NC_013008.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 5169311 actP 8219730 actP Escherichia coli O157:H7 str. TW14359 acetate permease YP_003080924.1 5167662 R 544404 CDS YP_003080925.1 254796088 8219731 complement(5169308..5169622) 1 NC_013008.1 acetate transport inner membrane protein 5169622 yjcH 8219731 yjcH Escherichia coli O157:H7 str. TW14359 acetate transport inner membrane protein YP_003080925.1 5169308 R 544404 CDS YP_003080926.1 254796089 8219732 complement(5169823..5171781) 1 NC_013008.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 5171781 acs 8219732 acs Escherichia coli O157:H7 str. TW14359 acetyl-CoA synthetase YP_003080926.1 5169823 R 544404 CDS YP_003080927.1 254796090 8219733 5172174..5173610 1 NC_013008.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 5173610 nrfA 8219733 nrfA Escherichia coli O157:H7 str. TW14359 cytochrome c552 YP_003080927.1 5172174 D 544404 CDS YP_003080928.1 254796091 8219734 5173655..5174221 1 NC_013008.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 5174221 nrfB 8219734 nrfB Escherichia coli O157:H7 str. TW14359 cytochrome c nitrite reductase pentaheme subunit YP_003080928.1 5173655 D 544404 CDS YP_003080929.1 254796092 8219735 5174218..5174889 1 NC_013008.1 formate-dependent nitrite reductase, 4Fe4S subunit 5174889 nrfC 8219735 nrfC Escherichia coli O157:H7 str. TW14359 formate-dependent nitrite reductase, 4Fe4S subunit YP_003080929.1 5174218 D 544404 CDS YP_003080930.1 254796093 8219736 5174886..5175842 1 NC_013008.1 formate-dependent nitrite reductase, membrane subunit 5175842 nrfD 8219736 nrfD Escherichia coli O157:H7 str. TW14359 formate-dependent nitrite reductase, membrane subunit YP_003080930.1 5174886 D 544404 CDS YP_003080931.1 254796094 8219737 5175922..5177580 1 NC_013008.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 5177580 nrfE 8219737 nrfE Escherichia coli O157:H7 str. TW14359 heme lyase subunit NrfE YP_003080931.1 5175922 D 544404 CDS YP_003080932.1 254796095 8219738 5177573..5177956 1 NC_013008.1 formate-dependent nitrite reductase complex subunit NrfF 5177956 nrfF 8219738 nrfF Escherichia coli O157:H7 str. TW14359 formate-dependent nitrite reductase complex subunit NrfF YP_003080932.1 5177573 D 544404 CDS YP_003080933.1 254796096 8219739 5177953..5178549 1 NC_013008.1 formate-dependent nitrite reductase complex subunit NrfG 5178549 nrfG 8219739 nrfG Escherichia coli O157:H7 str. TW14359 formate-dependent nitrite reductase complex subunit NrfG YP_003080933.1 5177953 D 544404 CDS YP_003080934.1 254796097 8219740 5178891..5180204 1 NC_013008.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 5180204 gltP 8219740 gltP Escherichia coli O157:H7 str. TW14359 glutamate/aspartate:proton symporter YP_003080934.1 5178891 D 544404 CDS YP_003080935.1 254796098 8219741 complement(5180382..5181071) 1 NC_013008.1 hypothetical protein 5181071 yjcO 8219741 yjcO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080935.1 5180382 R 544404 CDS YP_003080936.1 254796099 8219742 complement(5181165..5182844) 1 NC_013008.1 formate dehydrogenase-H, selenopolypeptide subunit 5182844 fdhF 8219742 fdhF Escherichia coli O157:H7 str. TW14359 formate dehydrogenase-H, selenopolypeptide subunit YP_003080936.1 5181165 R 544404 CDS YP_003080937.1 254796100 8219743 complement(5183510..5184976) 1 NC_013008.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 5184976 yjcP 8219743 yjcP Escherichia coli O157:H7 str. TW14359 outer membrane efflux protein MdtP YP_003080937.1 5183510 R 544404 CDS YP_003080938.1 254796101 8219744 complement(5184973..5187024) 1 NC_013008.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 5187024 yjcQ 8219744 yjcQ Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein MdtO YP_003080938.1 5184973 R 544404 CDS YP_003080939.1 254796102 8219745 complement(5187024..5188055) 1 NC_013008.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 5188055 yjcR 8219745 yjcR Escherichia coli O157:H7 str. TW14359 multidrug resistance protein MdtN YP_003080939.1 5187024 R 544404 CDS YP_003080940.1 254796103 8219746 complement(5188074..5188349) 1 NC_013008.1 hypothetical protein 5188349 8219746 ECSP_5180 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080940.1 5188074 R 544404 CDS YP_003080941.1 254796104 8219747 complement(5188466..5188585) 1 NC_013008.1 hypothetical protein 5188585 8219747 ECSP_5181 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080941.1 5188466 R 544404 CDS YP_003080942.1 254796105 8219748 complement(5188558..5190543) 1 NC_013008.1 alkyl sulfatase 5190543 yjcS 8219748 yjcS Escherichia coli O157:H7 str. TW14359 alkyl sulfatase YP_003080942.1 5188558 R 544404 CDS YP_003080943.1 254796106 8219749 5190834..5191541 1 NC_013008.1 transcriptional regulator 5191541 8219749 ECSP_5183 Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003080943.1 5190834 D 544404 CDS YP_003080944.1 254796107 8219750 complement(5191538..5192539) 1 NC_013008.1 kinase 5192539 8219750 ECSP_5184 Escherichia coli O157:H7 str. TW14359 kinase YP_003080944.1 5191538 R 544404 CDS YP_003080945.1 254796108 8219751 complement(5192536..5193396) 1 NC_013008.1 hypothetical protein 5193396 8219751 ECSP_5185 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080945.1 5192536 R 544404 CDS YP_003080946.1 254796109 8219752 complement(5193411..5194094) 1 NC_013008.1 hypothetical protein 5194094 8219752 ECSP_5186 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080946.1 5193411 R 544404 CDS YP_003080947.1 254796110 8219753 complement(5194149..5195090) 1 NC_013008.1 periplasmic ribose-binding protein of ABC transport system 5195090 8219753 ECSP_5187 Escherichia coli O157:H7 str. TW14359 periplasmic ribose-binding protein of ABC transport system YP_003080947.1 5194149 R 544404 CDS YP_003080948.1 254796111 8219754 complement(5195109..5196083) 1 NC_013008.1 permease of ribose ABC transport system 5196083 8219754 ECSP_5188 Escherichia coli O157:H7 str. TW14359 permease of ribose ABC transport system YP_003080948.1 5195109 R 544404 CDS YP_003080949.1 254796112 8219755 complement(5196080..5197600) 1 NC_013008.1 ATP-binding protein of ribose ABC transport system 5197600 8219755 ECSP_5189 Escherichia coli O157:H7 str. TW14359 ATP-binding protein of ribose ABC transport system YP_003080949.1 5196080 R 544404 CDS YP_003080950.1 254796113 8219756 5197714..5199984 1 NC_013008.1 histidine kinase 5199984 8219756 ECSP_5190 Escherichia coli O157:H7 str. TW14359 histidine kinase YP_003080950.1 5197714 D 544404 CDS YP_003080951.1 254796114 8219757 5200053..5200382 1 NC_013008.1 hypothetical protein 5200382 yjdP 8219757 yjdP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080951.1 5200053 D 544404 CDS YP_003080952.1 254796115 8219758 complement(5200459..5201217) 1 NC_013008.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 5201217 phnP 8219758 phnP Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex accessory protein YP_003080952.1 5200459 R 544404 CDS YP_003080953.1 254796116 8219759 complement(5201219..5201644) 1 NC_013008.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 5201644 8219759 ECSP_5193 Escherichia coli O157:H7 str. TW14359 aminoalkylphosphonic acid N-acetyltransferase YP_003080953.1 5201219 R 544404 CDS YP_003080954.1 254796117 8219760 complement(5201641..5202198) 1 NC_013008.1 ribose 1,5-bisphosphokinase 5202198 phnN 8219760 phnN Escherichia coli O157:H7 str. TW14359 ribose 1,5-bisphosphokinase YP_003080954.1 5201641 R 544404 CDS YP_003080955.1 254796118 8219761 complement(5202198..5203334) 1 NC_013008.1 carbon-phosphorus lyase complex subunit 5203334 phnM 8219761 phnM Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex subunit YP_003080955.1 5202198 R 544404 CDS YP_003080956.1 254796119 8219762 complement(5203331..5204011) 1 NC_013008.1 carbon-phosphorus lyase complex subunit 5204011 phnL 8219762 phnL Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex subunit YP_003080956.1 5203331 R 544404 CDS YP_003080957.1 254796120 8219763 complement(5204122..5204880) 1 NC_013008.1 phosphonate C-P lyase system protein PhnK 5204880 phnK 8219763 phnK Escherichia coli O157:H7 str. TW14359 phosphonate C-P lyase system protein PhnK YP_003080957.1 5204122 R 544404 CDS YP_003080958.1 254796121 8219764 complement(5204877..5205722) 1 NC_013008.1 carbon-phosphorus lyase complex subunit 5205722 phnJ 8219764 phnJ Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex subunit YP_003080958.1 5204877 R 544404 CDS YP_003080959.1 254796122 8219765 complement(5205715..5206779) 1 NC_013008.1 carbon-phosphorus lyase complex subunit 5206779 phnI 8219765 phnI Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex subunit YP_003080959.1 5205715 R 544404 CDS YP_003080960.1 254796123 8219766 complement(5206779..5207363) 1 NC_013008.1 carbon-phosphorus lyase complex subunit 5207363 phnH 8219766 phnH Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex subunit YP_003080960.1 5206779 R 544404 CDS YP_003080961.1 254796124 8219767 complement(5207360..5207812) 1 NC_013008.1 carbon-phosphorus lyase complex subunit 5207812 phnG 8219767 phnG Escherichia coli O157:H7 str. TW14359 carbon-phosphorus lyase complex subunit YP_003080961.1 5207360 R 544404 CDS YP_003080962.1 254796125 8219768 complement(5207813..5208538) 1 NC_013008.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 5208538 phnF 8219768 phnF Escherichia coli O157:H7 str. TW14359 phosphonate metabolism transcriptional regulator PhnF YP_003080962.1 5207813 R 544404 CDS YP_003080963.1 254796126 8219769 complement(5208559..5209389) 1 NC_013008.1 membrane channel protein component of Pn transporter 5209389 phnE 8219769 phnE Escherichia coli O157:H7 str. TW14359 membrane channel protein component of Pn transporter YP_003080963.1 5208559 R 544404 CDS YP_003080964.1 254796127 8219770 complement(5209444..5210460) 1 NC_013008.1 phosphonate ABC transporter substrate-binding protein 5210460 phnD 8219770 phnD Escherichia coli O157:H7 str. TW14359 phosphonate ABC transporter substrate-binding protein YP_003080964.1 5209444 R 544404 CDS YP_003080965.1 254796128 8219771 complement(5210485..5211273) 1 NC_013008.1 phosphonate/organophosphate ester transporter subunit 5211273 phnC 8219771 phnC Escherichia coli O157:H7 str. TW14359 phosphonate/organophosphate ester transporter subunit YP_003080965.1 5210485 R 544404 CDS YP_003080966.1 254796129 8219772 complement(5211406..5211849) 1 NC_013008.1 hypothetical protein 5211849 phnB 8219772 phnB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080966.1 5211406 R 544404 CDS YP_003080967.1 254796130 8219773 complement(5212108..5212443) 1 NC_013008.1 hypothetical protein 5212443 phnA 8219773 phnA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080967.1 5212108 R 544404 CDS YP_003080968.1 254796131 8219774 5212845..5215073 1 NC_013008.1 hypothetical protein 5215073 yjdA 8219774 yjdA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080968.1 5212845 D 544404 CDS YP_003080969.1 254796132 8219775 5215070..5215948 1 NC_013008.1 hypothetical protein 5215948 yjcZ 8219775 yjcZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080969.1 5215070 D 544404 CDS YP_003080970.1 254796133 8219776 5216212..5217714 1 NC_013008.1 proline/glycine betaine transporter 5217714 proP 8219776 proP Escherichia coli O157:H7 str. TW14359 proline/glycine betaine transporter YP_003080970.1 5216212 D 544404 CDS YP_003080971.1 254796134 8219777 complement(5217891..5218982) 1 NC_013008.1 sensor protein BasS/PmrB 5218982 basS 8219777 basS Escherichia coli O157:H7 str. TW14359 sensor protein BasS/PmrB YP_003080971.1 5217891 R 544404 CDS YP_003080972.1 254796135 8219778 complement(5218992..5219660) 1 NC_013008.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 5219660 basR 8219778 basR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator BasR YP_003080972.1 5218992 R 544404 CDS YP_003080973.1 254796136 8219779 complement(5219657..5221300) 1 NC_013008.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 5221300 eptA 8219779 eptA Escherichia coli O157:H7 str. TW14359 cell division protein YP_003080973.1 5219657 R 544404 CDS YP_003080974.1 254796137 8219780 complement(5221404..5222741) 1 NC_013008.1 arginine:agmatin antiporter 5222741 adiC 8219780 adiC Escherichia coli O157:H7 str. TW14359 arginine:agmatin antiporter YP_003080974.1 5221404 R 544404 CDS YP_003080975.1 254796138 8219781 complement(5222878..5223639) 1 NC_013008.1 DNA-binding transcriptional activator 5223639 adiY 8219781 adiY Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator YP_003080975.1 5222878 R 544404 CDS YP_003080976.1 254796139 8219782 complement(5223964..5226234) 1 NC_013008.1 biodegradative arginine decarboxylase 5226234 adiA 8219782 adiA Escherichia coli O157:H7 str. TW14359 biodegradative arginine decarboxylase YP_003080976.1 5223964 R 544404 CDS YP_003080977.1 254796140 8219783 complement(5226430..5227338) 1 NC_013008.1 DNA-binding transcriptional regulator MelR 5227338 melR 8219783 melR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator MelR YP_003080977.1 5226430 R 544404 CDS YP_003080978.1 254796141 8219784 5227621..5228976 1 NC_013008.1 alpha-galactosidase 5228976 melA 8219784 melA Escherichia coli O157:H7 str. TW14359 alpha-galactosidase YP_003080978.1 5227621 D 544404 CDS YP_003080979.1 254796142 8219785 5229091..5230500 1 NC_013008.1 melibiose:sodium symporter 5230500 melB 8219785 melB Escherichia coli O157:H7 str. TW14359 melibiose:sodium symporter YP_003080979.1 5229091 D 544404 CDS YP_003080980.1 254796143 8219786 complement(5230639..5231268) 1 NC_013008.1 hypothetical protein 5231268 yjdF 8219786 yjdF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080980.1 5230639 R 544404 CDS YP_003080981.1 254796144 8219787 complement(5231391..5233037) 1 NC_013008.1 anaerobic class I fumarate hydratase 5233037 fumB 8219787 fumB Escherichia coli O157:H7 str. TW14359 anaerobic class I fumarate hydratase YP_003080981.1 5231391 R 544404 CDS YP_003080982.1 254796145 8219788 complement(5233115..5234455) 1 NC_013008.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 5234455 dcuB 8219788 dcuB Escherichia coli O157:H7 str. TW14359 anaerobic C4-dicarboxylate transporter YP_003080982.1 5233115 R 544404 CDS YP_003080983.1 254796146 8219789 complement(5235026..5235745) 1 NC_013008.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 5235745 dcuR 8219789 dcuR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator DcuR YP_003080983.1 5235026 R 544404 CDS YP_003080984.1 254796147 8219790 complement(5235742..5237373) 1 NC_013008.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 5237373 dcuS 8219790 dcuS Escherichia coli O157:H7 str. TW14359 sensory histidine kinase DcuS YP_003080984.1 5235742 R 544404 CDS YP_003080985.1 254796148 8219791 5237554..5237784 1 NC_013008.1 hypothetical protein 5237784 yjdI 8219791 yjdI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080985.1 5237554 D 544404 CDS YP_003080986.1 254796149 8219792 5237796..5238068 1 NC_013008.1 acyl-CoA N-acyltransferase domain-containing acyltransferase 5238068 yjdJ 8219792 yjdJ Escherichia coli O157:H7 str. TW14359 acyl-CoA N-acyltransferase domain-containing acyltransferase YP_003080986.1 5237796 D 544404 CDS YP_003080987.1 254796150 8219793 5238295..5238591 1 NC_013008.1 hypothetical protein 5238591 yjdK 8219793 yjdK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080987.1 5238295 D 544404 CDS YP_003080988.1 254796151 8219794 5238619..5238792 1 NC_013008.1 hypothetical protein 5238792 yjdO 8219794 yjdO Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003080988.1 5238619 D 544404 CDS YP_003080989.1 254796152 8219795 complement(5238911..5240428) 1 NC_013008.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 5240428 lysU 8219795 lysU Escherichia coli O157:H7 str. TW14359 lysyl-tRNA synthetase YP_003080989.1 5238911 R 544404 CDS YP_003080990.1 254796153 8219796 complement(5240665..5242122) 1 NC_013008.1 transporter 5242122 yjdL 8219796 yjdL Escherichia coli O157:H7 str. TW14359 transporter YP_003080990.1 5240665 R 544404 CDS YP_003080991.1 254796154 8219797 complement(5242181..5244328) 1 NC_013008.1 lysine decarboxylase 1 5244328 cadA 8219797 cadA Escherichia coli O157:H7 str. TW14359 lysine decarboxylase 1 YP_003080991.1 5242181 R 544404 CDS YP_003080992.1 254796155 8219798 complement(5244408..5245742) 1 NC_013008.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 5245742 cadB 8219798 cadB Escherichia coli O157:H7 str. TW14359 lysine/cadaverine antiporter YP_003080992.1 5244408 R 544404 CDS YP_003080993.1 254796156 8219799 complement(5246108..5247646) 1 NC_013008.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 5247646 cadC 8219799 cadC Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator CadC YP_003080993.1 5246108 R 544404 CDS YP_003080994.1 254796157 8219801 complement(5248445..5249020) 1 NC_013008.1 transcriptional regulator 5249020 yjdC 8219801 yjdC Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003080994.1 5248445 R 544404 CDS YP_003080995.1 254796158 8219802 complement(5249057..5250754) 1 NC_013008.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 5250754 dipZ 8219802 dipZ Escherichia coli O157:H7 str. TW14359 thiol:disulfide interchange protein YP_003080995.1 5249057 R 544404 CDS YP_003080996.1 254796159 8219803 complement(5250730..5251068) 1 NC_013008.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 5251068 cutA 8219803 cutA Escherichia coli O157:H7 str. TW14359 divalent-cation tolerance protein CutA YP_003080996.1 5250730 R 544404 CDS YP_003080997.1 254796160 8219804 complement(5251184..5252485) 1 NC_013008.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 5252485 dcuA 8219804 dcuA Escherichia coli O157:H7 str. TW14359 anaerobic C4-dicarboxylate transporter YP_003080997.1 5251184 R 544404 CDS YP_003080998.1 254796161 8219805 complement(5252603..5254039) 1 NC_013008.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 5254039 aspA 8219805 aspA Escherichia coli O157:H7 str. TW14359 aspartate ammonia-lyase YP_003080998.1 5252603 R 544404 CDS YP_003080999.1 254796162 8219806 5254376..5254852 1 NC_013008.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 5254852 fxsA 8219806 fxsA Escherichia coli O157:H7 str. TW14359 FxsA protein YP_003080999.1 5254376 D 544404 CDS YP_003081000.1 254796163 8219807 complement(5254673..5256124) 1 NC_013008.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 5256124 yjeH 8219807 yjeH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081000.1 5254673 R 544404 CDS YP_003081001.1 254796164 8219808 5256400..5256693 1 NC_013008.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 5256693 groES 8219808 groES Escherichia coli O157:H7 str. TW14359 co-chaperonin GroES YP_003081001.1 5256400 D 544404 CDS YP_003081002.1 254796165 8219809 5256737..5258383 1 NC_013008.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 5258383 groEL 8219809 groEL Escherichia coli O157:H7 str. TW14359 molecular chaperone GroEL YP_003081002.1 5256737 D 544404 CDS YP_003081003.1 254796166 8219810 5258521..5258874 1 NC_013008.1 hypothetical protein 5258874 yjeI 8219810 yjeI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081003.1 5258521 D 544404 CDS YP_003081004.1 254796167 8219811 complement(5259067..5259936) 1 NC_013008.1 hypothetical protein 5259936 yjeJ 8219811 yjeJ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081004.1 5259067 R 544404 CDS YP_003081005.1 254796168 8219812 complement(5260171..5261199) 1 NC_013008.1 lysine 2,3-aminomutase 5261199 yjeK 8219812 yjeK Escherichia coli O157:H7 str. TW14359 lysine 2,3-aminomutase YP_003081005.1 5260171 R 544404 CDS YP_003081006.1 254796169 8219813 5261241..5261807 1 NC_013008.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 5261807 efp 8219813 efp Escherichia coli O157:H7 str. TW14359 elongation factor P YP_003081006.1 5261241 D 544404 CDS YP_003081007.1 254796170 8219814 5261859..5261984 1 NC_013008.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 5261984 ecnA 8219814 ecnA Escherichia coli O157:H7 str. TW14359 entericidin A YP_003081007.1 5261859 D 544404 CDS YP_003081008.1 254796171 8219815 5262095..5262241 1 NC_013008.1 entericidin B membrane lipoprotein 5262241 ecnB 8219815 ecnB Escherichia coli O157:H7 str. TW14359 entericidin B membrane lipoprotein YP_003081008.1 5262095 D 544404 CDS YP_003081009.1 254796172 8219816 5262417..5262734 1 NC_013008.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 5262734 sugE 8219816 sugE Escherichia coli O157:H7 str. TW14359 quaternary ammonium compound-resistance protein SugE YP_003081009.1 5262417 D 544404 CDS YP_003081010.1 254796173 8219817 complement(5262731..5263264) 1 NC_013008.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 5263264 blc 8219817 blc Escherichia coli O157:H7 str. TW14359 outer membrane lipoprotein Blc YP_003081010.1 5262731 R 544404 CDS YP_003081011.1 254796174 8219818 complement(5263352..5264485) 1 NC_013008.1 beta-lactamase 5264485 ampC 8219818 ampC Escherichia coli O157:H7 str. TW14359 beta-lactamase YP_003081011.1 5263352 R 544404 CDS YP_003081012.1 254796175 8219819 complement(5264548..5264907) 1 NC_013008.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 5264907 frdD 8219819 frdD Escherichia coli O157:H7 str. TW14359 fumarate reductase subunit D YP_003081012.1 5264548 R 544404 CDS YP_003081013.1 254796176 8219820 complement(5264918..5265313) 1 NC_013008.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 5265313 frdC 8219820 frdC Escherichia coli O157:H7 str. TW14359 fumarate reductase subunit C YP_003081013.1 5264918 R 544404 CDS YP_003081014.1 254796177 8219821 complement(5265324..5266058) 1 NC_013008.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 5266058 frdB 8219821 frdB Escherichia coli O157:H7 str. TW14359 fumarate reductase iron-sulfur subunit YP_003081014.1 5265324 R 544404 CDS YP_003081015.1 254796178 8219822 complement(5266051..5267859) 1 NC_013008.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 5267859 frdA 8219822 frdA Escherichia coli O157:H7 str. TW14359 fumarate reductase flavoprotein subunit YP_003081015.1 5266051 R 544404 CDS YP_003081016.1 254796179 8219823 5268184..5269161 1 NC_013008.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 5269161 poxA 8219823 poxA Escherichia coli O157:H7 str. TW14359 lysyl-tRNA synthetase YP_003081016.1 5268184 D 544404 CDS YP_003081017.1 254796180 8219824 5269380..5270882 1 NC_013008.1 transporter 5270882 yjeM 8219824 yjeM Escherichia coli O157:H7 str. TW14359 transporter YP_003081017.1 5269380 D 544404 CDS YP_003081018.1 254796181 8219825 complement(5271033..5274356) 1 NC_013008.1 hypothetical protein 5274356 yjeP 8219825 yjeP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081018.1 5271033 R 544404 CDS YP_003081019.1 254796182 8219826 complement(5274378..5275346) 1 NC_013008.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 5275346 psd 8219826 psd Escherichia coli O157:H7 str. TW14359 phosphatidylserine decarboxylase YP_003081019.1 5274378 R 544404 CDS YP_003081020.1 254796183 8219827 complement(5275443..5276495) 1 NC_013008.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 5276495 rsgA 8219827 rsgA Escherichia coli O157:H7 str. TW14359 ribosome-associated GTPase YP_003081020.1 5275443 R 544404 CDS YP_003081021.1 254796184 8219828 5276590..5277135 1 NC_013008.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 5277135 orn 8219828 orn Escherichia coli O157:H7 str. TW14359 oligoribonuclease YP_003081021.1 5276590 D 544404 CDS YP_003081022.1 254796185 8219832 complement(5277914..5279053) 1 NC_013008.1 Fe-S electron transport protein 5279053 yjeS 8219832 yjeS Escherichia coli O157:H7 str. TW14359 Fe-S electron transport protein YP_003081022.1 5277914 R 544404 CDS YP_003081023.1 254796186 8219833 5279052..5280599 1 NC_013008.1 hypothetical protein 5280599 yjeF 8219833 yjeF Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081023.1 5279052 D 544404 CDS YP_003081024.1 254796187 8219834 5280571..5281032 1 NC_013008.1 possibly involved in cell wall synthesis; ATPase 5281032 yjeE 8219834 yjeE Escherichia coli O157:H7 str. TW14359 ATPase YP_003081024.1 5280571 D 544404 CDS YP_003081025.1 254796188 8219835 5281051..5282388 1 NC_013008.1 N-acetylmuramoyl-l-alanine amidase II 5282388 amiB 8219835 amiB Escherichia coli O157:H7 str. TW14359 N-acetylmuramoyl-l-alanine amidase II YP_003081025.1 5281051 D 544404 CDS YP_003081026.1 254796189 8219836 5282398..5284245 1 NC_013008.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 5284245 mutL 8219836 mutL Escherichia coli O157:H7 str. TW14359 DNA mismatch repair protein YP_003081026.1 5282398 D 544404 CDS YP_003081027.1 254796190 8219837 5284238..5285188 1 NC_013008.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 5285188 miaA 8219837 miaA Escherichia coli O157:H7 str. TW14359 tRNA delta(2)-isopentenylpyrophosphate transferase YP_003081027.1 5284238 D 544404 CDS YP_003081028.1 254796191 8219838 5285274..5285582 1 NC_013008.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 5285582 hfq 8219838 hfq Escherichia coli O157:H7 str. TW14359 RNA-binding protein Hfq YP_003081028.1 5285274 D 544404 CDS YP_003081029.1 254796192 8219839 5285659..5286939 1 NC_013008.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 5286939 hflX 8219839 hflX Escherichia coli O157:H7 str. TW14359 GTPase HflX YP_003081029.1 5285659 D 544404 CDS YP_003081030.1 254796193 8219840 5287025..5288284 1 NC_013008.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 5288284 hflK 8219840 hflK Escherichia coli O157:H7 str. TW14359 FtsH protease regulator HflK YP_003081030.1 5287025 D 544404 CDS YP_003081031.1 254796194 8219841 5288287..5289291 1 NC_013008.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 5289291 hflC 8219841 hflC Escherichia coli O157:H7 str. TW14359 FtsH protease regulator HflC YP_003081031.1 5288287 D 544404 CDS YP_003081032.1 254796195 8219842 5289373..5289570 1 NC_013008.1 hypothetical protein 5289570 yjeT 8219842 yjeT Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081032.1 5289373 D 544404 CDS YP_003081033.1 254796196 8219843 5289674..5290972 1 NC_013008.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5290972 purA 8219843 purA Escherichia coli O157:H7 str. TW14359 adenylosuccinate synthetase YP_003081033.1 5289674 D 544404 CDS YP_003081034.1 254796197 8219844 5291177..5291602 1 NC_013008.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 5291602 nsrR 8219844 nsrR Escherichia coli O157:H7 str. TW14359 transcriptional repressor NsrR YP_003081034.1 5291177 D 544404 CDS YP_003081035.1 254796198 8219845 5291641..5294082 1 NC_013008.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 5294082 rnr 8219845 rnr Escherichia coli O157:H7 str. TW14359 exoribonuclease R YP_003081035.1 5291641 D 544404 CDS YP_003081036.1 254796199 8219846 5294263..5294994 1 NC_013008.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 5294994 rlmB 8219846 rlmB Escherichia coli O157:H7 str. TW14359 23S rRNA (guanosine-2'-O-)-methyltransferase YP_003081036.1 5294263 D 544404 CDS YP_003081037.1 254796200 8219847 5295121..5295522 1 NC_013008.1 hypothetical protein 5295522 yjfI 8219847 yjfI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081037.1 5295121 D 544404 CDS YP_003081038.1 254796201 8219848 5295541..5296239 1 NC_013008.1 transcriptional regulator effector protein 5296239 yjfJ 8219848 yjfJ Escherichia coli O157:H7 str. TW14359 transcriptional regulator effector protein YP_003081038.1 5295541 D 544404 CDS YP_003081039.1 254796202 8219849 5296290..5296949 1 NC_013008.1 hypothetical protein 5296949 yjfK 8219849 yjfK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081039.1 5296290 D 544404 CDS YP_003081040.1 254796203 8219850 5296967..5297365 1 NC_013008.1 hypothetical protein 5297365 yjfL 8219850 yjfL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081040.1 5296967 D 544404 CDS YP_003081041.1 254796204 8219851 5297375..5298013 1 NC_013008.1 hypothetical protein 5298013 yjfM 8219851 yjfM Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081041.1 5297375 D 544404 CDS YP_003081042.1 254796205 8219852 5298016..5299179 1 NC_013008.1 synthetase/amidase 5299179 yjfC 8219852 yjfC Escherichia coli O157:H7 str. TW14359 synthetase/amidase YP_003081042.1 5298016 D 544404 CDS YP_003081043.1 254796206 8219853 5299263..5300888 1 NC_013008.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 5300888 aidB 8219853 aidB Escherichia coli O157:H7 str. TW14359 isovaleryl CoA dehydrogenase YP_003081043.1 5299263 D 544404 CDS YP_003081044.1 254796207 8219854 complement(5301005..5301280) 1 NC_013008.1 hypothetical protein 5301280 yjfN 8219854 yjfN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081044.1 5301005 R 544404 CDS YP_003081045.1 254796208 8219855 complement(5301429..5301758) 1 NC_013008.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 5301758 yjfO 8219855 yjfO Escherichia coli O157:H7 str. TW14359 biofilm stress and motility protein A YP_003081045.1 5301429 R 544404 CDS YP_003081046.1 254796209 8219856 5301940..5302689 1 NC_013008.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 5302689 yjfP 8219856 yjfP Escherichia coli O157:H7 str. TW14359 esterase YP_003081046.1 5301940 D 544404 CDS YP_003081047.1 254796210 8219857 complement(5302686..5303441) 1 NC_013008.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 5303441 ulaR 8219857 ulaR Escherichia coli O157:H7 str. TW14359 transcriptional repressor UlaR YP_003081047.1 5302686 R 544404 CDS YP_003081048.1 254796211 8219858 complement(5303549..5304613) 1 NC_013008.1 L-ascorbate 6-phosphate lactonase 5304613 ulaG 8219858 ulaG Escherichia coli O157:H7 str. TW14359 L-ascorbate 6-phosphate lactonase YP_003081048.1 5303549 R 544404 CDS YP_003081049.1 254796212 8219859 5304968..5306365 1 NC_013008.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 5306365 ulaA 8219859 ulaA Escherichia coli O157:H7 str. TW14359 PTS system ascorbate-specific transporter subunit IIC YP_003081049.1 5304968 D 544404 CDS YP_003081050.1 254796213 8219860 5306381..5306686 1 NC_013008.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 5306686 ulaB 8219860 ulaB Escherichia coli O157:H7 str. TW14359 PTS system L-ascorbate-specific transporter subunit IIB YP_003081050.1 5306381 D 544404 CDS YP_003081051.1 254796214 8219861 5306696..5307160 1 NC_013008.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 5307160 ulaC 8219861 ulaC Escherichia coli O157:H7 str. TW14359 PTS system L-ascorbate-specific transporter subunit IIA YP_003081051.1 5306696 D 544404 CDS YP_003081052.1 254796215 8219862 5307174..5307824 1 NC_013008.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 5307824 ulaD 8219862 ulaD Escherichia coli O157:H7 str. TW14359 3-keto-L-gulonate-6-phosphate decarboxylase YP_003081052.1 5307174 D 544404 CDS YP_003081053.1 254796216 8219863 5307834..5308688 1 NC_013008.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 5308688 ulaE 8219863 ulaE Escherichia coli O157:H7 str. TW14359 L-xylulose 5-phosphate 3-epimerase YP_003081053.1 5307834 D 544404 CDS YP_003081054.1 254796217 8219864 5308688..5309374 1 NC_013008.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 5309374 sgaE 8219864 sgaE Escherichia coli O157:H7 str. TW14359 L-ribulose-5-phosphate 4-epimerase YP_003081054.1 5308688 D 544404 CDS YP_003081055.1 254796218 8219865 complement(5309503..5309778) 1 NC_013008.1 hypothetical protein 5309778 yjfY 8219865 yjfY Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081055.1 5309503 R 544404 CDS YP_003081056.1 254796219 8219866 5310105..5310500 1 NC_013008.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 5310500 rpsF 8219866 rpsF Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S6 YP_003081056.1 5310105 D 544404 CDS YP_003081057.1 254796220 8219867 5310507..5310821 1 NC_013008.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 5310821 priB 8219867 priB Escherichia coli O157:H7 str. TW14359 primosomal replication protein N YP_003081057.1 5310507 D 544404 CDS YP_003081058.1 254796221 8219868 5310826..5311053 1 NC_013008.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5311053 rpsR 8219868 rpsR Escherichia coli O157:H7 str. TW14359 30S ribosomal protein S18 YP_003081058.1 5310826 D 544404 CDS YP_003081059.1 254796222 8219869 5311095..5311544 1 NC_013008.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 5311544 rplI 8219869 rplI Escherichia coli O157:H7 str. TW14359 50S ribosomal protein L9 YP_003081059.1 5311095 D 544404 CDS YP_003081060.1 254796223 8219870 complement(5311615..5312409) 1 NC_013008.1 hypothetical protein 5312409 yjfZ 8219870 yjfZ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081060.1 5311615 R 544404 CDS YP_003081061.1 254796224 8219871 complement(5312849..5313031) 1 NC_013008.1 hypothetical protein 5313031 8219871 ECSP_5305 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081061.1 5312849 R 544404 CDS YP_003081062.1 254796225 8219872 complement(5313032..5313463) 1 NC_013008.1 transposase 5313463 8219872 ECSP_5306 Escherichia coli O157:H7 str. TW14359 transposase YP_003081062.1 5313032 R 544404 CDS YP_003081063.1 254796226 8219873 5313471..5314679 1 NC_013008.1 virulence protein 5314679 8219873 ECSP_5307 Escherichia coli O157:H7 str. TW14359 virulence protein YP_003081063.1 5313471 D 544404 CDS YP_003081064.1 254796227 8219874 complement(5314814..5315452) 1 NC_013008.1 cell envelope opacity-associated protein 5315452 ytfB 8219874 ytfB Escherichia coli O157:H7 str. TW14359 cell envelope opacity-associated protein YP_003081064.1 5314814 R 544404 CDS YP_003081065.1 254796228 8219875 5315670..5316290 1 NC_013008.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 5316290 fklB 8219875 fklB Escherichia coli O157:H7 str. TW14359 peptidyl-prolyl cis-trans isomerase YP_003081065.1 5315670 D 544404 CDS YP_003081066.1 254796229 8219876 5316599..5318011 1 NC_013008.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 5318011 cycA 8219876 cycA Escherichia coli O157:H7 str. TW14359 D-alanine/D-serine/glycine permease YP_003081066.1 5316599 D 544404 CDS YP_003081067.1 254796230 8219877 complement(5318056..5318718) 1 NC_013008.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 5318718 ytfE 8219877 ytfE Escherichia coli O157:H7 str. TW14359 iron-sulfur cluster repair di-iron protein YP_003081067.1 5318056 R 544404 CDS YP_003081068.1 254796231 8219878 complement(5318826..5319791) 1 NC_013008.1 inner membrane protein 5319791 ytfF 8219878 ytfF Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003081068.1 5318826 R 544404 CDS YP_003081069.1 254796232 8219879 complement(5319899..5320759) 1 NC_013008.1 NAD(P)H:quinone oxidoreductase 5320759 ytfG 8219879 ytfG Escherichia coli O157:H7 str. TW14359 NAD(P)H:quinone oxidoreductase YP_003081069.1 5319899 R 544404 CDS YP_003081070.1 254796233 8219880 5320848..5321228 1 NC_013008.1 transcriptional regulator 5321228 ytfH 8219880 ytfH Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003081070.1 5320848 D 544404 CDS YP_003081071.1 254796234 8219881 complement(5321346..5323289) 1 NC_013008.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 5323289 cpdB 8219881 cpdB Escherichia coli O157:H7 str. TW14359 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_003081071.1 5321346 R 544404 CDS YP_003081072.1 254796235 8219882 5323479..5324219 1 NC_013008.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 5324219 cysQ 8219882 cysQ Escherichia coli O157:H7 str. TW14359 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_003081072.1 5323479 D 544404 CDS YP_003081073.1 254796236 8219883 5324431..5325369 1 NC_013008.1 hypothetical protein 5325369 ytfI 8219883 ytfI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081073.1 5324431 D 544404 CDS YP_003081074.1 254796237 8219884 complement(5325432..5325986) 1 NC_013008.1 transcriptional regulator 5325986 ytfJ 8219884 ytfJ Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003081074.1 5325432 R 544404 CDS YP_003081075.1 254796238 8219885 5326311..5326517 1 NC_013008.1 hypothetical protein 5326517 ytfK 8219885 ytfK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081075.1 5326311 D 544404 CDS YP_003081076.1 254796239 8219886 complement(5326596..5327939) 1 NC_013008.1 inner membrane protein 5327939 ytfL 8219886 ytfL Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003081076.1 5326596 R 544404 CDS YP_003081077.1 254796240 8219887 complement(5328262..5328900) 1 NC_013008.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 5328900 msrA 8219887 msrA Escherichia coli O157:H7 str. TW14359 methionine sulfoxide reductase A YP_003081077.1 5328262 R 544404 CDS YP_003081078.1 254796241 8219888 5329106..5330839 1 NC_013008.1 outer membrane protein and surface antigen 5330839 ytfM 8219888 ytfM Escherichia coli O157:H7 str. TW14359 outer membrane protein and surface antigen YP_003081078.1 5329106 D 544404 CDS YP_003081079.1 254796242 8219889 5330836..5334615 1 NC_013008.1 hypothetical protein 5334615 ytfN 8219889 ytfN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081079.1 5330836 D 544404 CDS YP_003081080.1 254796243 8219890 5334618..5334959 1 NC_013008.1 hypothetical protein 5334959 ytfP 8219890 ytfP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081080.1 5334618 D 544404 CDS YP_003081081.1 254796244 8219891 5335171..5335422 1 NC_013008.1 part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 5335422 chpS 8219891 chpS Escherichia coli O157:H7 str. TW14359 antitoxin ChpS YP_003081081.1 5335171 D 544404 CDS YP_003081082.1 254796245 8219892 5335416..5335766 1 NC_013008.1 toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 5335766 chpB 8219892 chpB Escherichia coli O157:H7 str. TW14359 toxin ChpB YP_003081082.1 5335416 D 544404 CDS YP_003081083.1 254796246 8219893 complement(5335846..5336376) 1 NC_013008.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 5336376 ppa 8219893 ppa Escherichia coli O157:H7 str. TW14359 inorganic pyrophosphatase YP_003081083.1 5335846 R 544404 CDS YP_003081084.1 254796247 8219894 5336686..5337642 1 NC_013008.1 sugar ABC transporter periplasmic-binding protein 5337642 ytfQ 8219894 ytfQ Escherichia coli O157:H7 str. TW14359 sugar ABC transporter periplasmic-binding protein YP_003081084.1 5336686 D 544404 CDS YP_003081085.1 254796248 8219895 5337782..5338474 1 NC_013008.1 sugar ABC transporter ATP-binding protein 5338474 ytfR 8219895 ytfR Escherichia coli O157:H7 str. TW14359 sugar ABC transporter ATP-binding protein YP_003081085.1 5337782 D 544404 CDS YP_003081086.1 254796249 8219896 5339295..5340320 1 NC_013008.1 sugar ABC transporter membrane protein 5340320 ytfT 8219896 ytfT Escherichia coli O157:H7 str. TW14359 sugar ABC transporter membrane protein YP_003081086.1 5339295 D 544404 CDS YP_003081087.1 254796250 8219897 5340307..5341302 1 NC_013008.1 membrane component of a sugar ABC transporter system; ABC transporter permease 5341302 yjfF 8219897 yjfF Escherichia coli O157:H7 str. TW14359 ABC transporter permease YP_003081087.1 5340307 D 544404 CDS YP_003081088.1 254796251 8219898 complement(5341335..5342333) 1 NC_013008.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 5342333 fbp 8219898 fbp Escherichia coli O157:H7 str. TW14359 fructose-1,6-bisphosphatase YP_003081088.1 5341335 R 544404 CDS YP_003081089.1 254796252 8219899 5342509..5343882 1 NC_013008.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- me so-diaminopimelate ligase 5343882 mpl 8219899 mpl Escherichia coli O157:H7 str. TW14359 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- me so-diaminopimelate ligase YP_003081089.1 5342509 D 544404 CDS YP_003081090.1 254796253 8219900 complement(5344038..5344589) 1 NC_013008.1 hypothetical protein 5344589 yjgA 8219900 yjgA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081090.1 5344038 R 544404 CDS YP_003081091.1 254796254 8219901 5344683..5346035 1 NC_013008.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 5346035 pmbA 8219901 pmbA Escherichia coli O157:H7 str. TW14359 peptidase PmbA YP_003081091.1 5344683 D 544404 CDS YP_003081092.1 254796255 8219902 5346219..5346605 1 NC_013008.1 soluble cytochrome b562 5346605 8219902 ECSP_5336 Escherichia coli O157:H7 str. TW14359 soluble cytochrome b562 YP_003081092.1 5346219 D 544404 CDS YP_003081093.1 254796256 8219903 complement(5346650..5347114) 1 NC_013008.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 5347114 nrdG 8219903 nrdG Escherichia coli O157:H7 str. TW14359 anaerobic ribonucleotide reductase-activating protein YP_003081093.1 5346650 R 544404 CDS YP_003081094.1 254796257 8219904 5347103..5347297 1 NC_013008.1 hypothetical protein 5347297 8219904 ECSP_5338 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081094.1 5347103 D 544404 CDS YP_003081095.1 254796258 8219905 complement(5347304..5349442) 1 NC_013008.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 5349442 nrdD 8219905 nrdD Escherichia coli O157:H7 str. TW14359 anaerobic ribonucleoside triphosphate reductase YP_003081095.1 5347304 R 544404 CDS YP_003081096.1 254796259 8219906 complement(5349836..5351491) 1 NC_013008.1 trehalose-6-phosphate hydrolase 5351491 treC 8219906 treC Escherichia coli O157:H7 str. TW14359 trehalose-6-phosphate hydrolase YP_003081096.1 5349836 R 544404 CDS YP_003081097.1 254796260 8219907 complement(5351541..5352962) 1 NC_013008.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 5352962 treB 8219907 treB Escherichia coli O157:H7 str. TW14359 PTS system trehalose(maltose)-specific transporter subunits IIBC YP_003081097.1 5351541 R 544404 CDS YP_003081098.1 254796261 8219908 complement(5353081..5354028) 1 NC_013008.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 5354028 treR 8219908 treR Escherichia coli O157:H7 str. TW14359 trehalose repressor YP_003081098.1 5353081 R 544404 CDS YP_003081099.1 254796262 8219909 5354078..5354266 1 NC_013008.1 hypothetical protein 5354266 8219909 ECSP_5343 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081099.1 5354078 D 544404 CDS YP_003081100.1 254796263 8219910 5354407..5357103 1 NC_013008.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 5357103 mgtA 8219910 mgtA Escherichia coli O157:H7 str. TW14359 magnesium-transporting ATPase MgtA YP_003081100.1 5354407 D 544404 CDS YP_003081101.1 254796264 8219911 complement(5357309..5357695) 1 NC_013008.1 ketoacid-binding protein 5357695 yjgF 8219911 yjgF Escherichia coli O157:H7 str. TW14359 ketoacid-binding protein YP_003081101.1 5357309 R 544404 CDS YP_003081102.1 254796265 8219912 complement(5357768..5358229) 1 NC_013008.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 5358229 pyrI 8219912 pyrI Escherichia coli O157:H7 str. TW14359 aspartate carbamoyltransferase YP_003081102.1 5357768 R 544404 CDS YP_003081103.1 254796266 8219913 complement(5358242..5359177) 1 NC_013008.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 5359177 pyrB 8219913 pyrB Escherichia coli O157:H7 str. TW14359 aspartate carbamoyltransferase YP_003081103.1 5358242 R 544404 CDS YP_003081104.1 254796267 8219914 complement(5359181..5359372) 1 NC_013008.1 pyrBI operon leader peptide 5359372 8219914 ECSP_5348 Escherichia coli O157:H7 str. TW14359 pyrBI operon leader peptide YP_003081104.1 5359181 R 544404 CDS YP_003081105.1 254796268 8219915 complement(5359354..5359491) 1 NC_013008.1 hypothetical protein 5359491 8219915 ECSP_5349 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081105.1 5359354 R 544404 CDS YP_003081106.1 254796269 8219916 complement(5359596..5359991) 1 NC_013008.1 mRNA endoribonuclease 5359991 yjgH 8219916 yjgH Escherichia coli O157:H7 str. TW14359 mRNA endoribonuclease YP_003081106.1 5359596 R 544404 CDS YP_003081107.1 254796270 8219917 complement(5360122..5360835) 1 NC_013008.1 oxidoreductase 5360835 yjgI 8219917 yjgI Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003081107.1 5360122 R 544404 CDS YP_003081108.1 254796271 8219918 5360906..5361499 1 NC_013008.1 transcriptional regulator 5361499 yjgJ 8219918 yjgJ Escherichia coli O157:H7 str. TW14359 transcriptional regulator YP_003081108.1 5360906 D 544404 CDS YP_003081109.1 254796272 8219919 5361644..5362096 1 NC_013008.1 hypothetical protein 5362096 yjgK 8219919 yjgK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081109.1 5361644 D 544404 CDS YP_003081110.1 254796273 8219920 5362219..5363955 1 NC_013008.1 hypothetical protein 5363955 yjgL 8219920 yjgL Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081110.1 5362219 D 544404 CDS YP_003081111.1 254796274 8219921 complement(5364012..5365016) 1 NC_013008.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 5365016 argI 8219921 argI Escherichia coli O157:H7 str. TW14359 ornithine carbamoyltransferase subunit I YP_003081111.1 5364012 R 544404 CDS YP_003081112.1 254796275 8219922 5365178..5365594 1 NC_013008.1 hypothetical protein 5365594 rraB 8219922 rraB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081112.1 5365178 D 544404 CDS YP_003081113.1 254796276 8219923 complement(5365640..5366143) 1 NC_013008.1 acetyltransferase 5366143 yjgM 8219923 yjgM Escherichia coli O157:H7 str. TW14359 acetyltransferase YP_003081113.1 5365640 R 544404 CDS YP_003081114.1 254796277 8219924 5366336..5367532 1 NC_013008.1 hypothetical protein 5367532 yjgN 8219924 yjgN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081114.1 5366336 D 544404 CDS YP_003081115.1 254796278 8219925 complement(5367587..5370442) 1 NC_013008.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 5370442 valS 8219925 valS Escherichia coli O157:H7 str. TW14359 valyl-tRNA synthetase YP_003081115.1 5367587 R 544404 CDS YP_003081116.1 254796279 8219926 complement(5370442..5370885) 1 NC_013008.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 5370885 holC 8219926 holC Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit chi YP_003081116.1 5370442 R 544404 CDS YP_003081117.1 254796280 8219927 complement(5371239..5372750) 1 NC_013008.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 5372750 pepA 8219927 pepA Escherichia coli O157:H7 str. TW14359 leucyl aminopeptidase YP_003081117.1 5371239 R 544404 CDS YP_003081118.1 254796281 8219928 5373017..5374117 1 NC_013008.1 hypothetical protein 5374117 yjgP 8219928 yjgP Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081118.1 5373017 D 544404 CDS YP_003081119.1 254796282 8219929 5374117..5375199 1 NC_013008.1 hypothetical protein 5375199 yjgQ 8219929 yjgQ Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081119.1 5374117 D 544404 CDS YP_003081120.1 254796283 8219930 complement(5375360..5376862) 1 NC_013008.1 ATPase 5376862 yjgR 8219930 yjgR Escherichia coli O157:H7 str. TW14359 ATPase YP_003081120.1 5375360 R 544404 CDS YP_003081121.1 254796284 8219931 complement(5376992..5378011) 1 NC_013008.1 alcohol dehydrogenase, Zn-dependent and NAD(P)-binding 5378011 yjgB 8219931 yjgB Escherichia coli O157:H7 str. TW14359 alcohol dehydrogenase, Zn-dependent and NAD(P)-binding YP_003081121.1 5376992 R 544404 CDS YP_003081122.1 254796285 8219933 5378382..5380301 1 NC_013008.1 integrase 5380301 8219933 ECSP_5367 Escherichia coli O157:H7 str. TW14359 integrase YP_003081122.1 5378382 D 544404 CDS YP_003081123.1 254796286 8219934 complement(5380428..5380805) 1 NC_013008.1 hypothetical protein 5380805 8219934 ECSP_5368 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081123.1 5380428 R 544404 CDS YP_003081124.1 254796287 8219935 complement(5380927..5381193) 1 NC_013008.1 hypothetical protein 5381193 8219935 ECSP_5369 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081124.1 5380927 R 544404 CDS YP_003081125.1 254796288 8219936 complement(5382263..5382730) 1 NC_013008.1 hypothetical protein 5382730 8219936 ECSP_5370 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081125.1 5382263 R 544404 CDS YP_003081126.1 254796289 8219937 5382917..5383492 1 NC_013008.1 resolvase 5383492 8219937 ECSP_5371 Escherichia coli O157:H7 str. TW14359 resolvase YP_003081126.1 5382917 D 544404 CDS YP_003081127.1 254796290 8219938 complement(5383691..5385007) 1 NC_013008.1 hypothetical protein 5385007 8219938 ECSP_5372 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081127.1 5383691 R 544404 CDS YP_003081128.1 254796291 8219939 complement(5385159..5385932) 1 NC_013008.1 hypothetical protein 5385932 8219939 ECSP_5373 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081128.1 5385159 R 544404 CDS YP_003081129.1 254796292 8219940 5386049..5386513 1 NC_013008.1 hypothetical protein 5386513 8219940 ECSP_5374 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081129.1 5386049 D 544404 CDS YP_003081130.1 254796293 8219941 5386546..5386647 1 NC_013008.1 hypothetical protein 5386647 8219941 ECSP_5375 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081130.1 5386546 D 544404 CDS YP_003081131.1 254796294 8219942 5386669..5386782 1 NC_013008.1 hypothetical protein 5386782 8219942 ECSP_5376 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081131.1 5386669 D 544404 CDS YP_003081132.1 254796295 8219943 5387151..5388056 1 NC_013008.1 integrase 5388056 8219943 ECSP_5377 Escherichia coli O157:H7 str. TW14359 integrase YP_003081132.1 5387151 D 544404 CDS YP_003081133.1 254796296 8219944 5388170..5388283 1 NC_013008.1 hypothetical protein 5388283 8219944 ECSP_5378 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081133.1 5388170 D 544404 CDS YP_003081134.1 254796297 8219945 complement(5388516..5389367) 1 NC_013008.1 hypothetical protein 5389367 8219945 ECSP_5379 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081134.1 5388516 R 544404 CDS YP_003081135.1 254796298 8219946 complement(5389354..5389677) 1 NC_013008.1 hypothetical protein 5389677 8219946 ECSP_5380 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081135.1 5389354 R 544404 CDS YP_003081136.1 254796299 8219947 complement(5389908..5391011) 1 NC_013008.1 hypothetical protein 5391011 8219947 ECSP_5381 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081136.1 5389908 R 544404 CDS YP_003081137.1 254796300 8219948 complement(5391015..5391722) 1 NC_013008.1 hypothetical protein 5391722 8219948 ECSP_5382 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081137.1 5391015 R 544404 CDS YP_003081138.1 254796301 8219949 complement(5391729..5393381) 1 NC_013008.1 hypothetical protein 5393381 8219949 ECSP_5383 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081138.1 5391729 R 544404 CDS YP_003081139.1 254796302 8219950 5393599..5396952 1 NC_013008.1 hypothetical protein 5396952 8219950 ECSP_5384 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081139.1 5393599 D 544404 CDS YP_003081140.1 254796303 8219951 5396952..5403266 1 NC_013008.1 hypothetical protein 5403266 8219951 ECSP_5385 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081140.1 5396952 D 544404 CDS YP_003081141.1 254796304 8219952 5403490..5406348 1 NC_013008.1 ATP-dependent helicase 5406348 8219952 ECSP_5386 Escherichia coli O157:H7 str. TW14359 ATP-dependent helicase YP_003081141.1 5403490 D 544404 CDS YP_003081142.1 254796305 8219953 5406351..5411285 1 NC_013008.1 hypothetical protein 5411285 8219953 ECSP_5387 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081142.1 5406351 D 544404 CDS YP_003081143.1 254796306 8219954 5411285..5417626 1 NC_013008.1 helicase 5417626 8219954 ECSP_5388 Escherichia coli O157:H7 str. TW14359 helicase YP_003081143.1 5411285 D 544404 CDS YP_003081144.1 254796307 8219955 5417623..5419737 1 NC_013008.1 helicase 5419737 8219955 ECSP_5389 Escherichia coli O157:H7 str. TW14359 helicase YP_003081144.1 5417623 D 544404 CDS YP_003081145.1 254796308 8219956 complement(5420690..5420935) 1 NC_013008.1 hypothetical protein 5420935 8219956 ECSP_5390 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081145.1 5420690 R 544404 CDS YP_003081146.1 254796309 8219957 complement(5421231..5422211) 1 NC_013008.1 hypothetical protein 5422211 yjhS 8219957 yjhS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081146.1 5421231 R 544404 CDS YP_003081147.1 254796310 8219958 complement(5422276..5423382) 1 NC_013008.1 N-acetylneuraminic acid mutarotase 5423382 yjhT 8219958 yjhT Escherichia coli O157:H7 str. TW14359 N-acetylneuraminic acid mutarotase YP_003081147.1 5422276 R 544404 CDS YP_003081148.1 254796311 8219959 complement(5423402..5424118) 1 NC_013008.1 N-acetylnuraminic acid outer membrane channel protein 5424118 yjhA 8219959 yjhA Escherichia coli O157:H7 str. TW14359 N-acetylnuraminic acid outer membrane channel protein YP_003081148.1 5423402 R 544404 CDS YP_003081149.1 254796312 8219960 5424503..5424739 1 NC_013008.1 hypothetical protein 5424739 8219960 ECSP_5394 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081149.1 5424503 D 544404 CDS YP_003081150.1 254796313 8219961 complement(5424783..5424920) 1 NC_013008.1 hypothetical protein 5424920 8219961 ECSP_5395 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081150.1 5424783 R 544404 CDS YP_003081151.1 254796314 8219962 5425574..5426176 1 NC_013008.1 inversion of on/off regulator of fimA; tyrosine recombinase 5426176 fimB 8219962 fimB Escherichia coli O157:H7 str. TW14359 tyrosine recombinase YP_003081151.1 5425574 D 544404 CDS YP_003081152.1 254796315 8219963 5426654..5427250 1 NC_013008.1 inversion of on/off regulator of fimA; tyrosine recombinase 5427250 fimE 8219963 fimE Escherichia coli O157:H7 str. TW14359 tyrosine recombinase YP_003081152.1 5426654 D 544404 CDS YP_003081153.1 254796316 8219964 5427715..5428263 1 NC_013008.1 major type 1 subunit fimbrin 5428263 fimA 8219964 fimA Escherichia coli O157:H7 str. TW14359 major type 1 subunit fimbrin YP_003081153.1 5427715 D 544404 CDS YP_003081154.1 254796317 8219965 5428328..5428867 1 NC_013008.1 type 1 pilus biosynthesis fimbrial protein 5428867 fimI 8219965 fimI Escherichia coli O157:H7 str. TW14359 type 1 pilus biosynthesis fimbrial protein YP_003081154.1 5428328 D 544404 CDS YP_003081155.1 254796318 8219966 5428904..5429629 1 NC_013008.1 periplasmic chaperone, required for type 1 fimbriae 5429629 fimC 8219966 fimC Escherichia coli O157:H7 str. TW14359 periplasmic chaperone, required for type 1 fimbriae YP_003081155.1 5428904 D 544404 CDS YP_003081156.1 254796319 8219967 5429696..5432332 1 NC_013008.1 outer membrane usher protein, type 1 fimbrial synthesis 5432332 fimD 8219967 fimD Escherichia coli O157:H7 str. TW14359 outer membrane usher protein, type 1 fimbrial synthesis YP_003081156.1 5429696 D 544404 CDS YP_003081157.1 254796320 8219968 5432342..5432872 1 NC_013008.1 fimbrial morphology 5432872 fimF 8219968 fimF Escherichia coli O157:H7 str. TW14359 fimbrial morphology YP_003081157.1 5432342 D 544404 CDS YP_003081158.1 254796321 8219969 5432885..5433388 1 NC_013008.1 minor subunit of type 1 fimbriae 5433388 fimG 8219969 fimG Escherichia coli O157:H7 str. TW14359 minor subunit of type 1 fimbriae YP_003081158.1 5432885 D 544404 CDS YP_003081159.1 254796322 8219970 5433408..5434310 1 NC_013008.1 minor fimbrial subunit, D-mannose specific adhesin 5434310 fimH 8219970 fimH Escherichia coli O157:H7 str. TW14359 minor fimbrial subunit, D-mannose specific adhesin YP_003081159.1 5433408 D 544404 CDS YP_003081160.1 254796323 8219971 complement(5434484..5435827) 1 NC_013008.1 fructuronate transporter 5435827 gntP 8219971 gntP Escherichia coli O157:H7 str. TW14359 fructuronate transporter YP_003081160.1 5434484 R 544404 CDS YP_003081161.1 254796324 8219972 5436167..5437351 1 NC_013008.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5437351 uxuA 8219972 uxuA Escherichia coli O157:H7 str. TW14359 mannonate dehydratase YP_003081161.1 5436167 D 544404 CDS YP_003081162.1 254796325 8219973 5437432..5438892 1 NC_013008.1 D-mannonate oxidoreductase, NAD-binding 5438892 uxuB 8219973 uxuB Escherichia coli O157:H7 str. TW14359 D-mannonate oxidoreductase, NAD-binding YP_003081162.1 5437432 D 544404 CDS YP_003081163.1 254796326 8219974 5439107..5439880 1 NC_013008.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5439880 uxuR 8219974 uxuR Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional repressor UxuR YP_003081163.1 5439107 D 544404 CDS YP_003081164.1 254796327 8219975 complement(5440021..5440851) 1 NC_013008.1 hypothetical protein 5440851 yjiC 8219975 yjiC Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081164.1 5440021 R 544404 CDS YP_003081165.1 254796328 8219976 5441185..5441328 1 NC_013008.1 hypothetical protein 5441328 8219976 ECSP_5410 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081165.1 5441185 D 544404 CDS YP_003081166.1 254796329 8219977 5441524..5441916 1 NC_013008.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5441916 iraD 8219977 iraD Escherichia coli O157:H7 str. TW14359 DNA replication/recombination/repair protein YP_003081166.1 5441524 D 544404 CDS YP_003081167.1 254796330 8219979 complement(5442885..5444057) 1 NC_013008.1 isoaspartyl dipeptidase 5444057 iadA 8219979 iadA Escherichia coli O157:H7 str. TW14359 isoaspartyl dipeptidase YP_003081167.1 5442885 R 544404 CDS YP_003081168.1 254796331 8219980 complement(5444070..5444531) 1 NC_013008.1 hypothetical protein 5444531 yjiG 8219980 yjiG Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081168.1 5444070 R 544404 CDS YP_003081169.1 254796332 8219981 complement(5444528..5445211) 1 NC_013008.1 hypothetical protein 5445211 yjiH 8219981 yjiH Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081169.1 5444528 R 544404 CDS YP_003081170.1 254796333 8219982 5445359..5445805 1 NC_013008.1 2'-phosphotransferase 5445805 kptA 8219982 kptA Escherichia coli O157:H7 str. TW14359 2'-phosphotransferase YP_003081170.1 5445359 D 544404 CDS YP_003081171.1 254796334 8219983 complement(5446168..5451204) 1 NC_013008.1 invasin 5451204 8219983 ECSP_5417 Escherichia coli O157:H7 str. TW14359 invasin YP_003081171.1 5446168 R 544404 CDS YP_003081172.1 254796335 8219984 complement(5451620..5452798) 1 NC_013008.1 inner membrane protein 5452798 yjiJ 8219984 yjiJ Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003081172.1 5451620 R 544404 CDS YP_003081173.1 254796336 8219985 complement(5452866..5453855) 1 NC_013008.1 hypothetical protein 5453855 yjiK 8219985 yjiK Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081173.1 5452866 R 544404 CDS YP_003081174.1 254796337 8219986 complement(5453974..5456157) 1 NC_013008.1 non-LEE-encoded type III effector 5456157 espX6 8219986 espX6 Escherichia coli O157:H7 str. TW14359 non-LEE-encoded type III effector YP_003081174.1 5453974 R 544404 CDS YP_003081175.1 254796338 8219987 complement(5456732..5457499) 1 NC_013008.1 ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase 5457499 yjiL 8219987 yjiL Escherichia coli O157:H7 str. TW14359 ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase YP_003081175.1 5456732 R 544404 CDS YP_003081176.1 254796339 8219988 complement(5457509..5458660) 1 NC_013008.1 2-hydroxyglutaryl-CoA dehydratase 5458660 yjiM 8219988 yjiM Escherichia coli O157:H7 str. TW14359 2-hydroxyglutaryl-CoA dehydratase YP_003081176.1 5457509 R 544404 CDS YP_003081177.1 254796340 8219989 complement(5458776..5460047) 1 NC_013008.1 hypothetical protein 5460047 yjiN 8219989 yjiN Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081177.1 5458776 R 544404 CDS YP_003081178.1 254796341 8219990 complement(5460088..5461320) 1 NC_013008.1 multidrug efflux system protein 5461320 yjiO 8219990 yjiO Escherichia coli O157:H7 str. TW14359 multidrug efflux system protein YP_003081178.1 5460088 R 544404 CDS YP_003081179.1 254796342 8219992 complement(5462987..5464399) 1 NC_013008.1 fused DNA-binding transcriptional regulator, aminotransferase 5464399 yjiR 8219992 yjiR Escherichia coli O157:H7 str. TW14359 fused DNA-binding transcriptional regulator, aminotransferase YP_003081179.1 5462987 R 544404 CDS YP_003081180.1 254796343 8219993 5464576..5464740 1 NC_013008.1 hypothetical protein 5464740 yjiS 8219993 yjiS Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081180.1 5464576 D 544404 CDS YP_003081181.1 254796344 8219995 complement(5466976..5467317) 1 NC_013008.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 5467317 yjiW 8219995 yjiW Escherichia coli O157:H7 str. TW14359 endoribonuclease SymE YP_003081181.1 5466976 R 544404 CDS YP_003081182.1 254796345 8219996 complement(5467538..5469292) 1 NC_013008.1 restriction modification enzyme S subunit 5469292 8219996 ECSP_5430 Escherichia coli O157:H7 str. TW14359 restriction modification enzyme S subunit YP_003081182.1 5467538 R 544404 CDS YP_003081183.1 254796346 8219997 complement(5469292..5470773) 1 NC_013008.1 restriction modification enzyme M subunit (methylase) 5470773 8219997 ECSP_5431 Escherichia coli O157:H7 str. TW14359 restriction modification enzyme M subunit (methylase) YP_003081183.1 5469292 R 544404 CDS YP_003081184.1 254796347 8219998 complement(5470828..5473260) 1 NC_013008.1 restriction modification enzyme R subunit (endonuclease) 5473260 8219998 ECSP_5432 Escherichia coli O157:H7 str. TW14359 restriction modification enzyme R subunit (endonuclease) YP_003081184.1 5470828 R 544404 CDS YP_003081185.1 254796348 8220000 complement(5475258..5476214) 1 NC_013008.1 GTP-binding protein YjiA 5476214 yjiA 8220000 yjiA Escherichia coli O157:H7 str. TW14359 GTP-binding protein YjiA YP_003081185.1 5475258 R 544404 CDS YP_003081186.1 254796349 8220001 complement(5476225..5476428) 1 NC_013008.1 hypothetical protein 5476428 yjiX 8220001 yjiX Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081186.1 5476225 R 544404 CDS YP_003081187.1 254796350 8220002 complement(5476478..5478628) 1 NC_013008.1 inner membrane protein 5478628 yjiY 8220002 yjiY Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003081187.1 5476478 R 544404 CDS YP_003081188.1 254796351 8220003 complement(5478921..5479463) 1 NC_013008.1 hypothetical protein 5479463 8220003 ECSP_5437 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081188.1 5478921 R 544404 CDS YP_003081189.1 254796352 8220004 5479692..5481356 1 NC_013008.1 methyl-accepting chemotaxis protein I, serine sensor receptor 5481356 tsr 8220004 tsr Escherichia coli O157:H7 str. TW14359 methyl-accepting chemotaxis protein I, serine sensor receptor YP_003081189.1 5479692 D 544404 CDS YP_003081190.1 254796353 8220005 complement(5481405..5482766) 1 NC_013008.1 transporter 5482766 yjiZ 8220005 yjiZ Escherichia coli O157:H7 str. TW14359 transporter YP_003081190.1 5481405 R 544404 CDS YP_003081191.1 254796354 8220006 complement(5482981..5483895) 1 NC_013008.1 DNA-binding transcriptional regulator 5483895 yjjM 8220006 yjjM Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003081191.1 5482981 R 544404 CDS YP_003081192.1 254796355 8220007 5484034..5485056 1 NC_013008.1 oxidoreductase 5485056 yjjN 8220007 yjjN Escherichia coli O157:H7 str. TW14359 oxidoreductase YP_003081192.1 5484034 D 544404 CDS YP_003081193.1 254796356 8220008 complement(5485193..5487484) 1 NC_013008.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 5487484 mdoB 8220008 mdoB Escherichia coli O157:H7 str. TW14359 phosphoglycerol transferase I YP_003081193.1 5485193 R 544404 CDS YP_003081194.1 254796357 8220009 complement(5487738..5488232) 1 NC_013008.1 hypothetical protein 5488232 yjjA 8220009 yjjA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081194.1 5487738 R 544404 CDS YP_003081195.1 254796358 8220010 complement(5488281..5489018) 1 NC_013008.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 5489018 dnaC 8220010 dnaC Escherichia coli O157:H7 str. TW14359 DNA replication protein DnaC YP_003081195.1 5488281 R 544404 CDS YP_003081196.1 254796359 8220011 complement(5489021..5489560) 1 NC_013008.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 5489560 dnaT 8220011 dnaT Escherichia coli O157:H7 str. TW14359 primosomal protein DnaI YP_003081196.1 5489021 R 544404 CDS YP_003081197.1 254796360 8220012 complement(5489667..5490140) 1 NC_013008.1 hypothetical protein 5490140 yjjB 8220012 yjjB Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081197.1 5489667 R 544404 CDS YP_003081198.1 254796361 8220013 complement(5490131..5490901) 1 NC_013008.1 inner membrane protein 5490901 yjjP 8220013 yjjP Escherichia coli O157:H7 str. TW14359 inner membrane protein YP_003081198.1 5490131 R 544404 CDS YP_003081199.1 254796362 8220014 5491522..5492247 1 NC_013008.1 DNA-binding transcriptional regulator 5492247 yjjQ 8220014 yjjQ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional regulator YP_003081199.1 5491522 D 544404 CDS YP_003081200.1 254796363 8220015 5492355..5492882 1 NC_013008.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5492882 bglJ 8220015 bglJ Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator BglJ YP_003081200.1 5492355 D 544404 CDS YP_003081201.1 254796364 8220016 complement(5492920..5493708) 1 NC_013008.1 ferric iron reductase involved in ferric hydroximate transport 5493708 fhuF 8220016 fhuF Escherichia coli O157:H7 str. TW14359 ferric iron reductase involved in ferric hydroximate transport YP_003081201.1 5492920 R 544404 CDS YP_003081202.1 254796365 8220017 5493810..5494085 1 NC_013008.1 hypothetical protein 5494085 8220017 ECSP_5451 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081202.1 5493810 D 544404 CDS YP_003081203.1 254796366 8220019 complement(5494400..5495431) 1 NC_013008.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 5495431 rsmC 8220019 rsmC Escherichia coli O157:H7 str. TW14359 16S ribosomal RNA m2G1207 methyltransferase YP_003081203.1 5494400 R 544404 CDS YP_003081204.1 254796367 8220020 5495534..5495947 1 NC_013008.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5495947 holD 8220020 holD Escherichia coli O157:H7 str. TW14359 DNA polymerase III subunit psi YP_003081204.1 5495534 D 544404 CDS YP_003081205.1 254796368 8220021 5495916..5496362 1 NC_013008.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5496362 rimI 8220021 rimI Escherichia coli O157:H7 str. TW14359 ribosomal-protein-alanine N-acetyltransferase YP_003081205.1 5495916 D 544404 CDS YP_003081206.1 254796369 8220022 5496377..5497054 1 NC_013008.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5497054 yjjG 8220022 yjjG Escherichia coli O157:H7 str. TW14359 nucleotidase YP_003081206.1 5496377 D 544404 CDS YP_003081207.1 254796370 8220023 5497145..5498734 1 NC_013008.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5498734 prfC 8220023 prfC Escherichia coli O157:H7 str. TW14359 peptide chain release factor 3 YP_003081207.1 5497145 D 544404 CDS YP_003081208.1 254796371 8220024 5499127..5499732 1 NC_013008.1 periplasmic protein 5499732 osmY 8220024 osmY Escherichia coli O157:H7 str. TW14359 periplasmic protein YP_003081208.1 5499127 D 544404 CDS YP_003081209.1 254796372 8220025 5499859..5500020 1 NC_013008.1 hypothetical protein 5500020 ytjA 8220025 ytjA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081209.1 5499859 D 544404 CDS YP_003081210.1 254796373 8220026 5500142..5501215 1 NC_013008.1 esterase 5501215 yjjU 8220026 yjjU Escherichia coli O157:H7 str. TW14359 esterase YP_003081210.1 5500142 D 544404 CDS YP_003081211.1 254796374 8220027 5501212..5501994 1 NC_013008.1 deoxyribonuclease YjjV 5501994 yjjV 8220027 yjjV Escherichia coli O157:H7 str. TW14359 deoxyribonuclease YjjV YP_003081211.1 5501212 D 544404 CDS YP_003081212.1 254796375 8220028 complement(5502208..5503071) 1 NC_013008.1 pyruvate formate lyase activating enzyme 5503071 yjjW 8220028 yjjW Escherichia coli O157:H7 str. TW14359 pyruvate formate lyase activating enzyme YP_003081212.1 5502208 R 544404 CDS YP_003081213.1 254796376 8220029 complement(5503324..5504592) 1 NC_013008.1 hypothetical protein 5504592 yjjI 8220029 yjjI Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081213.1 5503324 R 544404 CDS YP_003081214.1 254796377 8220030 5504850..5505629 1 NC_013008.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5505629 deoC 8220030 deoC Escherichia coli O157:H7 str. TW14359 deoxyribose-phosphate aldolase YP_003081214.1 5504850 D 544404 CDS YP_003081215.1 254796378 8220031 5505756..5507078 1 NC_013008.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5507078 deoA 8220031 deoA Escherichia coli O157:H7 str. TW14359 thymidine phosphorylase YP_003081215.1 5505756 D 544404 CDS YP_003081216.1 254796379 8220032 5507130..5508353 1 NC_013008.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5508353 deoB 8220032 deoB Escherichia coli O157:H7 str. TW14359 phosphopentomutase YP_003081216.1 5507130 D 544404 CDS YP_003081217.1 254796380 8220033 5508410..5509129 1 NC_013008.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5509129 deoD 8220033 deoD Escherichia coli O157:H7 str. TW14359 purine nucleoside phosphorylase YP_003081217.1 5508410 D 544404 CDS YP_003081218.1 254796381 8220034 complement(5509290..5509553) 1 NC_013008.1 DNA binding protein 5509553 8220034 ECSP_5468 Escherichia coli O157:H7 str. TW14359 DNA binding protein YP_003081218.1 5509290 R 544404 CDS YP_003081219.1 254796382 8220035 complement(5509585..5511273) 1 NC_013008.1 in E. coli the lipoate ligase A catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes; creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; unknown domain/lipoate-protein ligase A fusion protein 5511273 8220035 ECSP_5469 Escherichia coli O157:H7 str. TW14359 unknown domain/lipoate-protein ligase A fusion protein YP_003081219.1 5509585 R 544404 CDS YP_003081220.1 254796383 8220036 5511379..5512347 1 NC_013008.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5512347 serB 8220036 serB Escherichia coli O157:H7 str. TW14359 phosphoserine phosphatase YP_003081220.1 5511379 D 544404 CDS YP_003081221.1 254796384 8220037 5512396..5513778 1 NC_013008.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5513778 radA 8220037 radA Escherichia coli O157:H7 str. TW14359 DNA repair protein RadA YP_003081221.1 5512396 D 544404 CDS YP_003081222.1 254796385 8220038 5513799..5515031 1 NC_013008.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5515031 nadR 8220038 nadR Escherichia coli O157:H7 str. TW14359 nicotinamide-nucleotide adenylyltransferase YP_003081222.1 5513799 D 544404 CDS YP_003081223.1 254796386 8220039 5515065..5515232 1 NC_013008.1 lipid A biosynthesis protein 5515232 8220039 ECSP_5473 Escherichia coli O157:H7 str. TW14359 lipid A biosynthesis protein YP_003081223.1 5515065 D 544404 CDS YP_003081224.1 254796387 8220040 complement(5515339..5517006) 1 NC_013008.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 5517006 yjjK 8220040 yjjK Escherichia coli O157:H7 str. TW14359 ABC transporter ATP-binding protein YP_003081224.1 5515339 R 544404 CDS YP_003081225.1 254796388 8220041 5517217..5519154 1 NC_013008.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5519154 slt 8220041 slt Escherichia coli O157:H7 str. TW14359 lytic murein transglycosylase YP_003081225.1 5517217 D 544404 CDS YP_003081226.1 254796389 8220042 5519244..5519570 1 NC_013008.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5519570 trpR 8220042 trpR Escherichia coli O157:H7 str. TW14359 Trp operon repressor YP_003081226.1 5519244 D 544404 CDS YP_003081227.1 254796390 8220043 complement(5519717..5520229) 1 NC_013008.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 5520229 yjjX 8220043 yjjX Escherichia coli O157:H7 str. TW14359 NTPase YP_003081227.1 5519717 R 544404 CDS YP_003081228.1 254796391 8220044 5520281..5520928 1 NC_013008.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5520928 ytjC 8220044 ytjC Escherichia coli O157:H7 str. TW14359 phosphoglycerate mutase YP_003081228.1 5520281 D 544404 CDS YP_003081229.1 254796392 8220045 complement(5520925..5521794) 1 NC_013008.1 DNA-binding transcriptional activator 5521794 rob 8220045 rob Escherichia coli O157:H7 str. TW14359 DNA-binding transcriptional activator YP_003081229.1 5520925 R 544404 CDS YP_003081230.1 254796393 8220046 5522005..5522478 1 NC_013008.1 hypothetical protein 5522478 creA 8220046 creA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081230.1 5522005 D 544404 CDS YP_003081231.1 254796394 8220047 5522491..5523180 1 NC_013008.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5523180 creB 8220047 creB Escherichia coli O157:H7 str. TW14359 DNA-binding response regulator CreB YP_003081231.1 5522491 D 544404 CDS YP_003081232.1 254796395 8220048 5523180..5524604 1 NC_013008.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5524604 creC 8220048 creC Escherichia coli O157:H7 str. TW14359 sensory histidine kinase CreC YP_003081232.1 5523180 D 544404 CDS YP_003081233.1 254796396 8220049 5524662..5526014 1 NC_013008.1 hypothetical protein 5526014 8220049 ECSP_5483 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081233.1 5524662 D 544404 CDS YP_003081234.1 254796397 8220050 complement(5526074..5526790) 1 NC_013008.1 two-component response regulator 5526790 8220050 ECSP_5484 Escherichia coli O157:H7 str. TW14359 two-component response regulator YP_003081234.1 5526074 R 544404 CDS YP_003081235.1 254796398 8220051 5526886..5527026 1 NC_013008.1 hypothetical protein 5527026 8220051 ECSP_5485 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003081235.1 5526886 D 544404 CDS YP_003081236.1 254796399 8220052 5527426..5528112 1 NC_013008.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5528112 8220052 ECSP_5486 Escherichia coli O157:H7 str. TW14359 RNA methyltransferase YP_003081236.1 5527426 D 544404 CDS YP_003082135.1 254667449 8206983 1..2685 1 NC_013010.1 hypothetical protein 2685 tagA 8206983 tagA Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082135.1 1 D 544404 CDS YP_003082136.1 254667450 8206874 2772..3647 1 NC_013010.1 type II secretion protein 3647 etpC 8206874 etpC Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082136.1 2772 D 544404 CDS YP_003082137.1 254667451 8206875 3663..5615 1 NC_013010.1 type II secretion protein 5615 etpD 8206875 etpD Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082137.1 3663 D 544404 CDS YP_003082138.1 254667452 8206876 5615..7120 1 NC_013010.1 type II secretion protein 7120 etpE 8206876 etpE Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082138.1 5615 D 544404 CDS YP_003082139.1 254667453 8206877 7122..8345 1 NC_013010.1 type II secretion protein 8345 etpF 8206877 etpF Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082139.1 7122 D 544404 CDS YP_003082140.1 254667454 8206878 8376..8810 1 NC_013010.1 type II secretion protein 8810 etpG 8206878 etpG Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082140.1 8376 D 544404 CDS YP_003082141.1 254667455 8206879 8807..9361 1 NC_013010.1 type II secretion protein 9361 etpH 8206879 etpH Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082141.1 8807 D 544404 CDS YP_003082142.1 254667456 8206880 9376..9723 1 NC_013010.1 type II secretion protein 9723 etpI 8206880 etpI Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082142.1 9376 D 544404 CDS YP_003082143.1 254667457 8206881 9720..10319 1 NC_013010.1 type II secretion protein 10319 etpJ 8206881 etpJ Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082143.1 9720 D 544404 CDS YP_003082144.1 254667458 8206882 10316..11293 1 NC_013010.1 type II secretion protein 11293 etpK 8206882 etpK Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082144.1 10316 D 544404 CDS YP_003082145.1 254667459 8206883 11407..12504 1 NC_013010.1 type II secretion protein 12504 etpL 8206883 etpL Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082145.1 11407 D 544404 CDS YP_003082146.1 254667460 8206884 12491..13003 1 NC_013010.1 type II secretion protein 13003 etpM 8206884 etpM Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082146.1 12491 D 544404 CDS YP_003082147.1 254667461 8206885 13061..13894 1 NC_013010.1 type II secretion protein 13894 etpN 8206885 etpN Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082147.1 13061 D 544404 CDS YP_003082148.1 254667462 8206886 13989..14387 1 NC_013010.1 type II secretion protein 14387 etpO 8206886 etpO Escherichia coli O157:H7 str. TW14359 type II secretion protein YP_003082148.1 13989 D 544404 CDS YP_003082149.1 254667463 8206887 14566..14871 1 NC_013010.1 hypothetical protein 14871 8206887 ECSP_6015 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082149.1 14566 D 544404 CDS YP_003082150.1 254667464 8206888 14898..15737 1 NC_013010.1 hypothetical protein 15737 8206888 ECSP_6016 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082150.1 14898 D 544404 CDS YP_003082151.1 254667465 8206889 16278..16793 1 NC_013010.1 hemolysin transport protein 16793 hlyC 8206889 hlyC Escherichia coli O157:H7 str. TW14359 hemolysin transport protein YP_003082151.1 16278 D 544404 CDS YP_003082152.1 254667466 8206890 16795..19791 1 NC_013010.1 hemolysin toxin protein 19791 hlyA 8206890 hlyA Escherichia coli O157:H7 str. TW14359 hemolysin toxin protein YP_003082152.1 16795 D 544404 CDS YP_003082153.1 254667467 8206891 19841..21961 1 NC_013010.1 hemolysin transport protein 21961 hlyB 8206891 hlyB Escherichia coli O157:H7 str. TW14359 hemolysin transport protein YP_003082153.1 19841 D 544404 CDS YP_003082154.1 254667468 8206892 21965..23404 1 NC_013010.1 hemolysin transport protein 23404 hlyD 8206892 hlyD Escherichia coli O157:H7 str. TW14359 hemolysin transport protein YP_003082154.1 21965 D 544404 CDS YP_003082155.1 254667469 8206893 23471..23665 1 NC_013010.1 hypothetical protein 23665 8206893 ECSP_6021 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082155.1 23471 D 544404 CDS YP_003082156.1 254667470 8206894 23707..23979 1 NC_013010.1 hypothetical protein 23979 8206894 ECSP_6022 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082156.1 23707 D 544404 CDS YP_003082157.1 254667471 8206895 24148..24378 1 NC_013010.1 hypothetical protein 24378 8206895 ECSP_6023 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082157.1 24148 D 544404 CDS YP_003082158.1 254667472 8206896 24499..25239 1 NC_013010.1 replication protein 25239 8206896 ECSP_6024 Escherichia coli O157:H7 str. TW14359 replication protein YP_003082158.1 24499 D 544404 CDS YP_003082159.1 254667473 8206897 25329..25448 1 NC_013010.1 hypothetical protein 25448 8206897 ECSP_6025 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082159.1 25329 D 544404 CDS YP_003082160.1 254667474 8206898 complement(25524..26501) 1 NC_013010.1 replication protein 26501 8206898 ECSP_6026 Escherichia coli O157:H7 str. TW14359 replication protein YP_003082160.1 25524 R 544404 CDS YP_003082161.1 254667475 8206899 complement(26494..26664) 1 NC_013010.1 hypothetical protein 26664 8206899 ECSP_6027 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082161.1 26494 R 544404 CDS YP_003082162.1 254667476 8206900 complement(26909..27109) 1 NC_013010.1 hypothetical protein 27109 8206900 ECSP_6028 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082162.1 26909 R 544404 CDS YP_003082163.1 254667477 8206901 complement(27106..27726) 1 NC_013010.1 hypothetical protein 27726 8206901 ECSP_6029 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082163.1 27106 R 544404 CDS YP_003082164.1 254667478 8206902 complement(27723..28322) 1 NC_013010.1 hypothetical protein 28322 8206902 ECSP_6030 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082164.1 27723 R 544404 CDS YP_003082165.1 254667479 8206903 28347..28688 1 NC_013010.1 hypothetical protein 28688 8206903 ECSP_6031 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082165.1 28347 D 544404 CDS YP_003082166.1 254667480 8206904 28865..29083 1 NC_013010.1 plasmid maintenance protein CcdA 29083 ccdA 8206904 ccdA Escherichia coli O157:H7 str. TW14359 plasmid maintenance protein CcdA YP_003082166.1 28865 D 544404 CDS YP_003082167.1 254667481 8206905 complement(29137..30024) 1 NC_013010.1 transposase 30024 8206905 ECSP_6033 Escherichia coli O157:H7 str. TW14359 transposase YP_003082167.1 29137 R 544404 CDS YP_003082168.1 254667482 8206906 complement(30024..30350) 1 NC_013010.1 transposase 30350 8206906 ECSP_6034 Escherichia coli O157:H7 str. TW14359 transposase YP_003082168.1 30024 R 544404 CDS YP_003082169.1 254667483 8206907 30449..30703 1 NC_013010.1 controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 30703 ccdB 8206907 ccdB Escherichia coli O157:H7 str. TW14359 plasmid maintenance protein CcdB YP_003082169.1 30449 D 544404 CDS YP_003082170.1 254667484 8206908 30704..31510 1 NC_013010.1 resolvase 31510 redF 8206908 redF Escherichia coli O157:H7 str. TW14359 resolvase YP_003082170.1 30704 D 544404 CDS YP_003082171.1 254667485 8206909 complement(32233..33120) 1 NC_013010.1 transposase 33120 tra6 8206909 tra6 Escherichia coli O157:H7 str. TW14359 transposase YP_003082171.1 32233 R 544404 CDS YP_003082172.1 254667486 8206910 complement(33120..33446) 1 NC_013010.1 hypothetical protein 33446 8206910 ECSP_6038 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082172.1 33120 R 544404 CDS YP_003082173.1 254667487 8206911 33522..34277 1 NC_013010.1 RepE; RepFIB; replication protein 34277 8206911 ECSP_6039 Escherichia coli O157:H7 str. TW14359 replication protein YP_003082173.1 33522 D 544404 CDS YP_003082174.1 254667488 8206912 34865..36031 1 NC_013010.1 plasmid-partitioning protein SopA 36031 sopA 8206912 sopA Escherichia coli O157:H7 str. TW14359 plasmid-partitioning protein SopA YP_003082174.1 34865 D 544404 CDS YP_003082175.1 254667489 8206913 36031..37002 1 NC_013010.1 SopB; plasmid-partitioning protein 37002 sopB 8206913 sopB Escherichia coli O157:H7 str. TW14359 plasmid-partitioning protein YP_003082175.1 36031 D 544404 CDS YP_003082176.1 254667490 8206914 37697..38599 1 NC_013010.1 hypothetical protein 38599 8206914 ECSP_6042 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082176.1 37697 D 544404 CDS YP_003082177.1 254667491 8206915 38603..38908 1 NC_013010.1 hypothetical protein 38908 8206915 ECSP_6043 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082177.1 38603 D 544404 CDS YP_003082178.1 254667492 8206916 38985..39668 1 NC_013010.1 putative methylase 39668 8206916 ECSP_6044 Escherichia coli O157:H7 str. TW14359 putative methylase YP_003082178.1 38985 D 544404 CDS YP_003082179.1 254667493 8206917 39669..39890 1 NC_013010.1 hypothetical protein 39890 8206917 ECSP_6045 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082179.1 39669 D 544404 CDS YP_003082180.1 254667494 8206918 39904..40338 1 NC_013010.1 hypothetical protein 40338 8206918 ECSP_6046 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082180.1 39904 D 544404 CDS YP_003082181.1 254667495 8206919 40384..41160 1 NC_013010.1 hypothetical protein 41160 8206919 ECSP_6047 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082181.1 40384 D 544404 CDS YP_003082182.1 254667496 8206920 41033..41605 1 NC_013010.1 hypothetical protein 41605 8206920 ECSP_6048 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082182.1 41033 D 544404 CDS YP_003082183.1 254667497 8206921 41578..42003 1 NC_013010.1 hypothetical protein 42003 8206921 ECSP_6049 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082183.1 41578 D 544404 CDS YP_003082184.1 254667498 8206922 42050..42472 1 NC_013010.1 hypothetical protein 42472 8206922 ECSP_6050 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082184.1 42050 D 544404 CDS YP_003082185.1 254667499 8206923 42469..42660 1 NC_013010.1 hypothetical protein 42660 8206923 ECSP_6051 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082185.1 42469 D 544404 CDS YP_003082186.1 254667500 8206924 complement(42630..43160) 1 NC_013010.1 hypothetical protein 43160 8206924 ECSP_6052 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082186.1 42630 R 544404 CDS YP_003082187.1 254667501 8206925 43304..43432 1 NC_013010.1 hypothetical protein 43432 8206925 ECSP_6053 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082187.1 43304 D 544404 CDS YP_003082188.1 254667502 8206926 complement(43485..43634) 1 NC_013010.1 hypothetical protein 43634 8206926 ECSP_6054 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082188.1 43485 R 544404 CDS YP_003082189.1 254667503 8206927 43656..43886 1 NC_013010.1 hypothetical protein 43886 8206927 ECSP_6055 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082189.1 43656 D 544404 CDS YP_003082190.1 254667504 8206928 43938..45299 1 NC_013010.1 hypothetical protein 45299 8206928 ECSP_6056 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082190.1 43938 D 544404 CDS YP_003082191.1 254667505 8206929 45346..45909 1 NC_013010.1 hypothetical protein 45909 8206929 ECSP_6057 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082191.1 45346 D 544404 CDS YP_003082192.1 254667506 8206930 complement(45995..46444) 1 NC_013010.1 hypothetical protein 46444 8206930 ECSP_6058 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082192.1 45995 R 544404 CDS YP_003082193.1 254667507 8206931 46746..47198 1 NC_013010.1 single-stranded DNA-binding protein 47198 ssb 8206931 ssb Escherichia coli O157:H7 str. TW14359 single-stranded DNA-binding protein YP_003082193.1 46746 D 544404 CDS YP_003082194.1 254667508 8206932 47255..47488 1 NC_013010.1 hypothetical protein 47488 8206932 ECSP_6060 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082194.1 47255 D 544404 CDS YP_003082195.1 254667509 8206933 47554..49512 1 NC_013010.1 hypothetical protein 49512 8206933 ECSP_6061 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082195.1 47554 D 544404 CDS YP_003082196.1 254667510 8206934 49567..50001 1 NC_013010.1 plasmid SOS inhibition protein B 50001 psiB 8206934 psiB Escherichia coli O157:H7 str. TW14359 plasmid SOS inhibition protein B YP_003082196.1 49567 D 544404 CDS YP_003082197.1 254667511 8206935 49998..50759 1 NC_013010.1 PsiA; plasmid SOS inhibition protein A 50759 psiA 8206935 psiA Escherichia coli O157:H7 str. TW14359 plasmid SOS inhibition protein A YP_003082197.1 49998 D 544404 CDS YP_003082198.1 254667512 8206936 50991..51149 1 NC_013010.1 small toxic polypeptide 51149 flmA 8206936 flmA Escherichia coli O157:H7 str. TW14359 small toxic polypeptide YP_003082198.1 50991 D 544404 CDS YP_003082199.1 254667513 8206937 51331..53304 1 NC_013010.1 putative nickase 53304 8206937 ECSP_6065 Escherichia coli O157:H7 str. TW14359 putative nickase YP_003082199.1 51331 D 544404 CDS YP_003082200.1 254667514 8206938 53408..53803 1 NC_013010.1 hypothetical protein 53803 8206938 ECSP_6066 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082200.1 53408 D 544404 CDS YP_003082201.1 254667515 8206939 complement(54370..54759) 1 NC_013010.1 putative transposase 54759 8206939 ECSP_6067 Escherichia coli O157:H7 str. TW14359 putative transposase YP_003082201.1 54370 R 544404 CDS YP_003082202.1 254667516 8206940 54911..55321 1 NC_013010.1 transposase 55321 8206940 ECSP_6068 Escherichia coli O157:H7 str. TW14359 transposase YP_003082202.1 54911 D 544404 CDS YP_003082203.1 254667517 8206941 55394..55483 1 NC_013010.1 transposase 55483 8206941 ECSP_6069 Escherichia coli O157:H7 str. TW14359 transposase YP_003082203.1 55394 D 544404 CDS YP_003082204.1 254667518 8206942 55590..65099 1 NC_013010.1 putative cytotoxin 65099 8206942 ECSP_6070 Escherichia coli O157:H7 str. TW14359 putative cytotoxin YP_003082204.1 55590 D 544404 CDS YP_003082205.1 254667519 8206943 65191..65463 1 NC_013010.1 putative transposase 65463 8206943 ECSP_6071 Escherichia coli O157:H7 str. TW14359 putative transposase YP_003082205.1 65191 D 544404 CDS YP_003082206.1 254667520 8206944 complement(65390..65893) 1 NC_013010.1 hypothetical protein 65893 8206944 ECSP_6072 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082206.1 65390 R 544404 CDS YP_003082207.1 254667521 8206945 66040..67338 1 NC_013010.1 DNA helicase 67338 traI 8206945 traI Escherichia coli O157:H7 str. TW14359 DNA helicase YP_003082207.1 66040 D 544404 CDS YP_003082208.1 254667522 8206946 67358..68104 1 NC_013010.1 conjugal transfer pilus acetylation protein TraX 68104 traX 8206946 traX Escherichia coli O157:H7 str. TW14359 conjugal transfer pilus acetylation protein TraX YP_003082208.1 67358 D 544404 CDS YP_003082209.1 254667523 8206947 68163..69023 1 NC_013010.1 hypothetical protein 69023 8206947 ECSP_6075 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082209.1 68163 D 544404 CDS YP_003082210.1 254667524 8206948 69051..69686 1 NC_013010.1 conjugal transfer fertility inhibition protein FinO 69686 finO 8206948 finO Escherichia coli O157:H7 str. TW14359 conjugal transfer fertility inhibition protein FinO YP_003082210.1 69051 D 544404 CDS YP_003082211.1 254667525 8206949 69819..70031 1 NC_013010.1 hypothetical protein 70031 8206949 ECSP_6077 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082211.1 69819 D 544404 CDS YP_003082212.1 254667526 8206950 70216..70737 1 NC_013010.1 hypothetical protein 70737 8206950 ECSP_6078 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082212.1 70216 D 544404 CDS YP_003082213.1 254667527 8206951 70783..70992 1 NC_013010.1 hemolysin expression-modulating protein 70992 8206951 ECSP_6079 Escherichia coli O157:H7 str. TW14359 hemolysin expression-modulating protein YP_003082213.1 70783 D 544404 CDS YP_003082214.1 254667528 8206952 71030..71368 1 NC_013010.1 hypothetical protein 71368 8206952 ECSP_6080 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082214.1 71030 D 544404 CDS YP_003082215.1 254667529 8206953 71608..71862 1 NC_013010.1 replication protein 71862 8206953 ECSP_6081 Escherichia coli O157:H7 str. TW14359 replication protein YP_003082215.1 71608 D 544404 CDS YP_003082216.1 254667530 8206954 72098..72172 1 NC_013010.1 RepA6; leader peptide RepL 72172 8206954 ECSP_6082 Escherichia coli O157:H7 str. TW14359 leader peptide RepL YP_003082216.1 72098 D 544404 CDS YP_003082217.1 254667531 8206955 72153..73022 1 NC_013010.1 RepA; replication protein 73022 8206955 ECSP_6083 Escherichia coli O157:H7 str. TW14359 replication protein YP_003082217.1 72153 D 544404 CDS YP_003082218.1 254667532 8206956 73384..73578 1 NC_013010.1 replication protein 73578 8206956 ECSP_6084 Escherichia coli O157:H7 str. TW14359 replication protein YP_003082218.1 73384 D 544404 CDS YP_003082219.1 254667533 8206957 73998..74219 1 NC_013010.1 hypothetical protein 74219 8206957 ECSP_6085 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082219.1 73998 D 544404 CDS YP_003082220.1 254667534 8206958 74219..74494 1 NC_013010.1 hypothetical protein 74494 8206958 ECSP_6086 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082220.1 74219 D 544404 CDS YP_003082221.1 254667535 8206959 complement(74565..74852) 1 NC_013010.1 hypothetical protein 74852 8206959 ECSP_6087 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082221.1 74565 R 544404 CDS YP_003082222.1 254667536 8206960 complement(74880..75101) 1 NC_013010.1 transposase 75101 8206960 ECSP_6088 Escherichia coli O157:H7 str. TW14359 transposase YP_003082222.1 74880 R 544404 CDS YP_003082223.1 254667537 8206961 complement(75154..75633) 1 NC_013010.1 hypothetical protein 75633 8206961 ECSP_6089 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082223.1 75154 R 544404 CDS YP_003082224.1 254667538 8206962 complement(75672..76181) 1 NC_013010.1 transposase 76181 8206962 ECSP_6090 Escherichia coli O157:H7 str. TW14359 transposase YP_003082224.1 75672 R 544404 CDS YP_003082225.1 254667539 8206963 76166..76405 1 NC_013010.1 hypothetical protein 76405 8206963 ECSP_6091 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082225.1 76166 D 544404 CDS YP_003082226.1 254667540 8206964 76498..78708 1 NC_013010.1 EHEC-catalase/peroxidase 78708 katP 8206964 katP Escherichia coli O157:H7 str. TW14359 EHEC-catalase/peroxidase YP_003082226.1 76498 D 544404 CDS YP_003082227.1 254667541 8206965 78752..79141 1 NC_013010.1 hypothetical protein 79141 8206965 ECSP_6093 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082227.1 78752 D 544404 CDS YP_003082228.1 254667542 8206966 79147..79299 1 NC_013010.1 hypothetical protein 79299 8206966 ECSP_6094 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082228.1 79147 D 544404 CDS YP_003082229.1 254667543 8206967 79299..80186 1 NC_013010.1 transposase 80186 8206967 ECSP_6095 Escherichia coli O157:H7 str. TW14359 transposase YP_003082229.1 79299 D 544404 CDS YP_003082230.1 254667544 8206968 80367..84269 1 NC_013010.1 putative exoprotein-precursor 84269 espP 8206968 espP Escherichia coli O157:H7 str. TW14359 putative exoprotein-precursor YP_003082230.1 80367 D 544404 CDS YP_003082231.1 254667545 8206969 complement(84432..84572) 1 NC_013010.1 hypothetical protein 84572 8206969 ECSP_6097 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082231.1 84432 R 544404 CDS YP_003082232.1 254667546 8206970 complement(84734..85006) 1 NC_013010.1 transposase 85006 insA 8206970 insA Escherichia coli O157:H7 str. TW14359 transposase YP_003082232.1 84734 R 544404 CDS YP_003082233.1 254667547 8206971 85306..85428 1 NC_013010.1 transposase 85428 8206971 ECSP_6099 Escherichia coli O157:H7 str. TW14359 transposase YP_003082233.1 85306 D 544404 CDS YP_003082234.1 254667548 8206972 85691..85846 1 NC_013010.1 regulatory protein 85846 8206972 ECSP_6100 Escherichia coli O157:H7 str. TW14359 regulatory protein YP_003082234.1 85691 D 544404 CDS YP_003082235.1 254667549 8206973 86061..86180 1 NC_013010.1 hypothetical protein 86180 8206973 ECSP_6101 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082235.1 86061 D 544404 CDS YP_003082236.1 254667550 8206974 86478..87269 1 NC_013010.1 hypothetical protein 87269 8206974 ECSP_6102 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082236.1 86478 D 544404 CDS YP_003082237.1 254667551 8206975 87272..88375 1 NC_013010.1 hypothetical protein 88375 8206975 ECSP_6103 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082237.1 87272 D 544404 CDS YP_003082238.1 254667552 8206976 88465..90186 1 NC_013010.1 hypothetical protein 90186 8206976 ECSP_6104 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082238.1 88465 D 544404 CDS YP_003082239.1 254667553 8206977 90227..91258 1 NC_013010.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 91258 8206977 ECSP_6105 Escherichia coli O157:H7 str. TW14359 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_003082239.1 90227 D 544404 CDS YP_003082240.1 254667554 8206978 91626..92006 1 NC_013010.1 transposase 92006 8206978 ECSP_6106 Escherichia coli O157:H7 str. TW14359 transposase YP_003082240.1 91626 D 544404 CDS YP_003082241.1 254667555 8206979 92003..92350 1 NC_013010.1 transposase 92350 8206979 ECSP_6107 Escherichia coli O157:H7 str. TW14359 transposase YP_003082241.1 92003 D 544404 CDS YP_003082242.1 254667556 8206980 92400..93938 1 NC_013010.1 transposase 93938 8206980 ECSP_6108 Escherichia coli O157:H7 str. TW14359 transposase YP_003082242.1 92400 D 544404 CDS YP_003082243.1 254667557 8206981 complement(94029..94145) 1 NC_013010.1 hypothetical protein 94145 8206981 ECSP_6109 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082243.1 94029 R 544404 CDS YP_003082244.1 254667558 8206982 complement(94312..94527) 1 NC_013010.1 hypothetical protein 94527 8206982 ECSP_6110 Escherichia coli O157:H7 str. TW14359 hypothetical protein YP_003082244.1 94312 R 544404 CDS