-- dump date 20140619_090000 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 544404000001 SEQ_END SEQ_END NC_013008.1 5528136 5528136 DR NC_013008.1; contig end 5528136..5528136 Escherichia coli O157:H7 str. TW14359 544404000002 SEQ_END SEQ_END NC_013010.1 94601 94601 DR NC_013010.1; contig end 94601..94601 Escherichia coli O157:H7 str. TW14359 YP_003075974.1 CDS ECSP_0001 NC_013008.1 133 351 R hypothetical protein complement(133..351) Escherichia coli O157:H7 str. TW14359 8220053 YP_003075975.1 CDS thrA NC_013008.1 360 2816 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 360..2816 Escherichia coli O157:H7 str. TW14359 8214568 YP_003075976.1 CDS ECSP_0003 NC_013008.1 2818 3750 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2818..3750 Escherichia coli O157:H7 str. TW14359 8214569 YP_003075977.1 CDS thrC NC_013008.1 3751 5037 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3751..5037 Escherichia coli O157:H7 str. TW14359 8214570 YP_003075978.1 CDS yaaX NC_013008.1 5251 5547 D hypothetical protein 5251..5547 Escherichia coli O157:H7 str. TW14359 8214571 YP_003075979.1 CDS yaaA NC_013008.1 5700 6476 R hypothetical protein complement(5700..6476) Escherichia coli O157:H7 str. TW14359 8214572 YP_003075980.1 CDS yaaJ NC_013008.1 6546 7976 R transporter complement(6546..7976) Escherichia coli O157:H7 str. TW14359 8214573 YP_003075981.1 CDS talB NC_013008.1 8255 9208 D transaldolase B 8255..9208 Escherichia coli O157:H7 str. TW14359 8214574 YP_003075982.1 CDS mogA NC_013008.1 9323 9910 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9323..9910 Escherichia coli O157:H7 str. TW14359 8214575 YP_003075983.1 CDS yaaH NC_013008.1 9945 10511 R hypothetical protein complement(9945..10511) Escherichia coli O157:H7 str. TW14359 8214576 YP_003075984.1 CDS yaaW NC_013008.1 10660 11373 R hypothetical protein complement(10660..11373) Escherichia coli O157:H7 str. TW14359 8214577 YP_003075985.1 CDS yaaI NC_013008.1 11399 11803 R hypothetical protein complement(11399..11803) Escherichia coli O157:H7 str. TW14359 8214578 YP_003075986.1 CDS ECSP_0013 NC_013008.1 11938 12087 R hypothetical protein complement(11938..12087) Escherichia coli O157:H7 str. TW14359 8214579 YP_003075987.1 CDS dnaK NC_013008.1 12180 14096 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12180..14096 Escherichia coli O157:H7 str. TW14359 8214580 YP_003075988.1 CDS dnaJ NC_013008.1 14185 15315 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 14185..15315 Escherichia coli O157:H7 str. TW14359 8214581 YP_003075989.1 CDS mokC NC_013008.1 15419 15628 R regulatory peptide complement(15419..15628) Escherichia coli O157:H7 str. TW14359 8214582 YP_003075990.1 CDS nhaA NC_013008.1 16157 17323 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 16157..17323 Escherichia coli O157:H7 str. TW14359 8214583 YP_003075991.1 CDS nhaR NC_013008.1 17383 18288 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 17383..18288 Escherichia coli O157:H7 str. TW14359 8214584 YP_003075992.1 CDS ECSP_0021 NC_013008.1 21762 22445 R chaperone protein complement(21762..22445) Escherichia coli O157:H7 str. TW14359 8214587 YP_003075993.1 CDS ECSP_0022 NC_013008.1 22495 23028 R type-1 fimbrial protein complement(22495..23028) Escherichia coli O157:H7 str. TW14359 8214588 YP_003075994.1 CDS espX1 NC_013008.1 23330 24751 R non-LEE-encoded type III effector complement(23330..24751) Escherichia coli O157:H7 str. TW14359 8214589 YP_003075995.1 CDS rpsT NC_013008.1 25221 25484 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(25221..25484) Escherichia coli O157:H7 str. TW14359 8214590 YP_003075996.1 CDS yaaY NC_013008.1 25587 25811 D hypothetical protein 25587..25811 Escherichia coli O157:H7 str. TW14359 8214591 YP_003075997.1 CDS ribF NC_013008.1 25819 26760 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 25819..26760 Escherichia coli O157:H7 str. TW14359 8214592 YP_003075998.1 CDS ileS NC_013008.1 26803 29619 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 26803..29619 Escherichia coli O157:H7 str. TW14359 8214593 YP_003075999.1 CDS lspA NC_013008.1 29619 30113 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 29619..30113 Escherichia coli O157:H7 str. TW14359 8214594 YP_003076000.1 CDS fkpB NC_013008.1 30201 30650 D FKBP-type peptidylprolyl isomerase 30201..30650 Escherichia coli O157:H7 str. TW14359 8214595 YP_003076001.1 CDS ispH NC_013008.1 30652 31602 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30652..31602 Escherichia coli O157:H7 str. TW14359 8214596 YP_003076002.1 CDS rihC NC_013008.1 31668 32582 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 31668..32582 Escherichia coli O157:H7 str. TW14359 8214597 YP_003076003.1 CDS dapB NC_013008.1 32749 33570 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 32749..33570 Escherichia coli O157:H7 str. TW14359 8214598 YP_003076004.1 CDS ECSP_0033 NC_013008.1 33849 33986 D hypothetical protein 33849..33986 Escherichia coli O157:H7 str. TW14359 8214599 YP_003076005.1 CDS carA NC_013008.1 34026 35174 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 34026..35174 Escherichia coli O157:H7 str. TW14359 8214600 YP_003076006.1 CDS carB NC_013008.1 35192 38413 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 35192..38413 Escherichia coli O157:H7 str. TW14359 8214601 YP_003076007.1 CDS ECSP_0036 NC_013008.1 38421 38639 R hypothetical protein complement(38421..38639) Escherichia coli O157:H7 str. TW14359 8214602 YP_003076008.1 CDS caiF NC_013008.1 38674 39069 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 38674..39069 Escherichia coli O157:H7 str. TW14359 8214603 YP_003076009.1 CDS caiE NC_013008.1 39188 39778 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(39188..39778) Escherichia coli O157:H7 str. TW14359 8214604 YP_003076010.1 CDS caiD NC_013008.1 39784 40569 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(39784..40569) Escherichia coli O157:H7 str. TW14359 8214605 YP_003076011.1 CDS caiC NC_013008.1 40678 42231 R crotonobetaine/carnitine-CoA ligase complement(40678..42231) Escherichia coli O157:H7 str. TW14359 8214606 YP_003076012.1 CDS caiB NC_013008.1 42305 43522 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(42305..43522) Escherichia coli O157:H7 str. TW14359 8214607 YP_003076013.1 CDS caiA NC_013008.1 43651 44793 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(43651..44793) Escherichia coli O157:H7 str. TW14359 8214608 YP_003076014.1 CDS caiT NC_013008.1 44824 46338 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(44824..46338) Escherichia coli O157:H7 str. TW14359 8214609 YP_003076015.1 CDS fixA NC_013008.1 46812 47582 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 46812..47582 Escherichia coli O157:H7 str. TW14359 8214610 YP_003076016.1 CDS fixB NC_013008.1 47597 48538 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 47597..48538 Escherichia coli O157:H7 str. TW14359 8214611 YP_003076017.1 CDS fixC NC_013008.1 48589 49875 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 48589..49875 Escherichia coli O157:H7 str. TW14359 8214612 YP_003076018.1 CDS fixX NC_013008.1 49872 50159 D 4Fe-4S ferredoxin-type protein 49872..50159 Escherichia coli O157:H7 str. TW14359 8214613 YP_003076019.1 CDS yaaU NC_013008.1 50217 51548 D transporter 50217..51548 Escherichia coli O157:H7 str. TW14359 8214614 YP_003076020.1 CDS kefF NC_013008.1 51656 52186 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 51656..52186 Escherichia coli O157:H7 str. TW14359 8214615 YP_003076021.1 CDS kefC NC_013008.1 52179 54041 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52179..54041 Escherichia coli O157:H7 str. TW14359 8214616 YP_003076022.1 CDS folA NC_013008.1 54233 54712 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 54233..54712 Escherichia coli O157:H7 str. TW14359 8214617 YP_003076023.1 CDS ECSP_0052 NC_013008.1 54798 55031 D antitoxin of gyrase inhibiting toxin-antitoxin system 54798..55031 Escherichia coli O157:H7 str. TW14359 8214618 YP_003076024.1 CDS ECSP_0053 NC_013008.1 55034 55348 D toxin of gyrase inhibiting toxin-antitoxin system 55034..55348 Escherichia coli O157:H7 str. TW14359 8214619 YP_003076025.1 CDS apaH NC_013008.1 55345 56193 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(55345..56193) Escherichia coli O157:H7 str. TW14359 8214620 YP_003076026.1 CDS apaG NC_013008.1 56200 56577 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(56200..56577) Escherichia coli O157:H7 str. TW14359 8214621 YP_003076027.1 CDS ksgA NC_013008.1 56580 57401 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(56580..57401) Escherichia coli O157:H7 str. TW14359 8214622 YP_003076028.1 CDS pdxA NC_013008.1 57398 58387 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(57398..58387) Escherichia coli O157:H7 str. TW14359 8214623 YP_003076029.1 CDS surA NC_013008.1 58387 59673 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(58387..59673) Escherichia coli O157:H7 str. TW14359 8214624 YP_003076030.1 CDS imp NC_013008.1 59726 62080 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(59726..62080) Escherichia coli O157:H7 str. TW14359 8214625 YP_003076031.1 CDS djlA NC_013008.1 62335 63150 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 62335..63150 Escherichia coli O157:H7 str. TW14359 8214626 YP_003076032.1 CDS espY1 NC_013008.1 63445 64182 D non-LEE-encoded type III effector 63445..64182 Escherichia coli O157:H7 str. TW14359 8214627 YP_003076033.1 CDS rluA NC_013008.1 64600 65259 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(64600..65259) Escherichia coli O157:H7 str. TW14359 8214628 YP_003076034.1 CDS hepA NC_013008.1 65271 68177 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(65271..68177) Escherichia coli O157:H7 str. TW14359 8214629 YP_003076035.1 CDS polB NC_013008.1 68341 70692 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(68341..70692) Escherichia coli O157:H7 str. TW14359 8214630 YP_003076036.1 CDS araD NC_013008.1 70767 71462 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(70767..71462) Escherichia coli O157:H7 str. TW14359 8214631 YP_003076037.1 CDS araA NC_013008.1 71662 73164 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(71662..73164) Escherichia coli O157:H7 str. TW14359 8214632 YP_003076038.1 CDS araB NC_013008.1 73175 74875 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(73175..74875) Escherichia coli O157:H7 str. TW14359 8214633 YP_003076039.1 CDS araC NC_013008.1 75214 76092 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; AraC family transcriptional regulator 75214..76092 Escherichia coli O157:H7 str. TW14359 8214634 YP_003076040.1 CDS yabI NC_013008.1 76178 76942 D hypothetical protein 76178..76942 Escherichia coli O157:H7 str. TW14359 8214635 YP_003076041.1 CDS thiQ NC_013008.1 77029 77727 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(77029..77727) Escherichia coli O157:H7 str. TW14359 8214636 YP_003076042.1 CDS thiP NC_013008.1 77711 79321 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(77711..79321) Escherichia coli O157:H7 str. TW14359 8214637 YP_003076043.1 CDS tbpA NC_013008.1 79297 80280 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(79297..80280) Escherichia coli O157:H7 str. TW14359 8214638 YP_003076044.1 CDS espY2 NC_013008.1 80652 81221 D non-LEE-encoded type III effector 80652..81221 Escherichia coli O157:H7 str. TW14359 8214639 YP_003076045.1 CDS sgrR NC_013008.1 81450 83108 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(81450..83108) Escherichia coli O157:H7 str. TW14359 8214640 YP_003076046.1 CDS leuD NC_013008.1 83436 84041 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(83436..84041) Escherichia coli O157:H7 str. TW14359 8214641 YP_003076047.1 CDS leuC NC_013008.1 84052 85452 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(84052..85452) Escherichia coli O157:H7 str. TW14359 8214642 YP_003076048.1 CDS leuB NC_013008.1 85455 86546 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(85455..86546) Escherichia coli O157:H7 str. TW14359 8214643 YP_003076049.1 CDS leuA NC_013008.1 86546 88117 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(86546..88117) Escherichia coli O157:H7 str. TW14359 8214644 YP_003076050.1 CDS leuL NC_013008.1 88210 88296 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(88210..88296) Escherichia coli O157:H7 str. TW14359 8214645 YP_003076051.1 CDS leuO NC_013008.1 88954 89898 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 88954..89898 Escherichia coli O157:H7 str. TW14359 8214646 YP_003076052.1 CDS ilvI NC_013008.1 90216 91940 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 90216..91940 Escherichia coli O157:H7 str. TW14359 8214647 YP_003076053.1 CDS ilvH NC_013008.1 91943 92434 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 91943..92434 Escherichia coli O157:H7 str. TW14359 8214648 YP_003076054.1 CDS fruR NC_013008.1 92614 93618 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 92614..93618 Escherichia coli O157:H7 str. TW14359 8214649 YP_003076055.1 CDS mraZ NC_013008.1 94220 94678 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 94220..94678 Escherichia coli O157:H7 str. TW14359 8214650 YP_003076056.1 CDS mraW NC_013008.1 94680 95621 D S-adenosyl-methyltransferase MraW 94680..95621 Escherichia coli O157:H7 str. TW14359 8214651 YP_003076057.1 CDS ftsL NC_013008.1 95618 95983 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 95618..95983 Escherichia coli O157:H7 str. TW14359 8214652 YP_003076058.1 CDS ftsI NC_013008.1 95999 97765 D transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 95999..97765 Escherichia coli O157:H7 str. TW14359 8214653 YP_003076059.1 CDS murE NC_013008.1 97752 99239 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 97752..99239 Escherichia coli O157:H7 str. TW14359 8214654 YP_003076060.1 CDS murF NC_013008.1 99236 100594 D UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 99236..100594 Escherichia coli O157:H7 str. TW14359 8214655 YP_003076061.1 CDS mraY NC_013008.1 100588 101670 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 100588..101670 Escherichia coli O157:H7 str. TW14359 8214656 YP_003076062.1 CDS murD NC_013008.1 101673 102989 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 101673..102989 Escherichia coli O157:H7 str. TW14359 8214657 YP_003076063.1 CDS ftsW NC_013008.1 102989 104233 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 102989..104233 Escherichia coli O157:H7 str. TW14359 8214658 YP_003076064.1 CDS murG NC_013008.1 104230 105297 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 104230..105297 Escherichia coli O157:H7 str. TW14359 8214659 YP_003076065.1 CDS murC NC_013008.1 105351 106826 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 105351..106826 Escherichia coli O157:H7 str. TW14359 8214660 YP_003076066.1 CDS ddl NC_013008.1 106819 107739 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 106819..107739 Escherichia coli O157:H7 str. TW14359 8214661 YP_003076067.1 CDS ftsQ NC_013008.1 107741 108571 D involved in septum formation; cell division protein FtsQ 107741..108571 Escherichia coli O157:H7 str. TW14359 8214662 YP_003076068.1 CDS ftsA NC_013008.1 108568 109830 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 108568..109830 Escherichia coli O157:H7 str. TW14359 8214663 YP_003076069.1 CDS ftsZ NC_013008.1 109891 111042 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 109891..111042 Escherichia coli O157:H7 str. TW14359 8214664 YP_003076070.1 CDS lpxC NC_013008.1 111143 112060 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 111143..112060 Escherichia coli O157:H7 str. TW14359 8214665 YP_003076071.1 CDS secM NC_013008.1 112291 112803 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112291..112803 Escherichia coli O157:H7 str. TW14359 8214666 YP_003076072.1 CDS secA NC_013008.1 112865 115570 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 112865..115570 Escherichia coli O157:H7 str. TW14359 8214667 YP_003076073.1 CDS mutT NC_013008.1 115630 116028 D nucleoside triphosphate pyrophosphohydrolase 115630..116028 Escherichia coli O157:H7 str. TW14359 8214668 YP_003076074.1 CDS yacG NC_013008.1 116119 116316 R zinc-binding protein complement(116119..116316) Escherichia coli O157:H7 str. TW14359 8214669 YP_003076075.1 CDS yacF NC_013008.1 116326 117069 R hypothetical protein complement(116326..117069) Escherichia coli O157:H7 str. TW14359 8214670 YP_003076076.1 CDS coaE NC_013008.1 117069 117689 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(117069..117689) Escherichia coli O157:H7 str. TW14359 8214671 YP_003076077.1 CDS guaC NC_013008.1 117914 118957 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 117914..118957 Escherichia coli O157:H7 str. TW14359 8214672 YP_003076078.1 CDS hcpC NC_013008.1 118992 120194 R type IV pilin biogenesis protein complement(118992..120194) Escherichia coli O157:H7 str. TW14359 8214673 YP_003076079.1 CDS hcpB NC_013008.1 120184 121569 R hypothetical protein complement(120184..121569) Escherichia coli O157:H7 str. TW14359 8214674 YP_003076080.1 CDS hcpA NC_013008.1 121579 122019 R major pilin subunit complement(121579..122019) Escherichia coli O157:H7 str. TW14359 8214675 YP_003076081.1 CDS nadC NC_013008.1 122222 123115 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(122222..123115) Escherichia coli O157:H7 str. TW14359 8214676 YP_003076082.1 CDS ampD NC_013008.1 123203 123754 D N-acetyl-anhydromuranmyl-L-alanine amidase 123203..123754 Escherichia coli O157:H7 str. TW14359 8214677 YP_003076083.1 CDS ampE NC_013008.1 123751 124605 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 123751..124605 Escherichia coli O157:H7 str. TW14359 8214678 YP_003076084.1 CDS aroP NC_013008.1 124648 126021 R aromatic amino acid transporter complement(124648..126021) Escherichia coli O157:H7 str. TW14359 8214679 YP_003076085.1 CDS pdhR NC_013008.1 126562 127326 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 126562..127326 Escherichia coli O157:H7 str. TW14359 8214680 YP_003076086.1 CDS aceE NC_013008.1 127487 130150 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 127487..130150 Escherichia coli O157:H7 str. TW14359 8214681 YP_003076087.1 CDS aceF NC_013008.1 130165 132057 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 130165..132057 Escherichia coli O157:H7 str. TW14359 8214682 YP_003076088.1 CDS lpd NC_013008.1 132265 133689 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 132265..133689 Escherichia coli O157:H7 str. TW14359 8214683 YP_003076089.1 CDS yacH NC_013008.1 133760 135613 R hypothetical protein complement(133760..135613) Escherichia coli O157:H7 str. TW14359 8214684 YP_003076090.1 CDS acnB NC_013008.1 135968 138565 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 135968..138565 Escherichia coli O157:H7 str. TW14359 8214685 YP_003076091.1 CDS yacL NC_013008.1 138741 139103 D hypothetical protein 138741..139103 Escherichia coli O157:H7 str. TW14359 8214686 YP_003076092.1 CDS speD NC_013008.1 139141 139935 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(139141..139935) Escherichia coli O157:H7 str. TW14359 8214687 YP_003076093.1 CDS speE NC_013008.1 139951 140817 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(139951..140817) Escherichia coli O157:H7 str. TW14359 8214688 YP_003076094.1 CDS yacC NC_013008.1 140923 141270 R hypothetical protein complement(140923..141270) Escherichia coli O157:H7 str. TW14359 8214689 YP_003076095.1 CDS cueO NC_013008.1 141436 142986 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 141436..142986 Escherichia coli O157:H7 str. TW14359 8214690 YP_003076096.1 CDS gcd NC_013008.1 143188 145578 R glucose dehydrogenase complement(143188..145578) Escherichia coli O157:H7 str. TW14359 8214691 YP_003076097.1 CDS hpt NC_013008.1 145784 146320 D hypoxanthine phosphoribosyltransferase 145784..146320 Escherichia coli O157:H7 str. TW14359 8214692 YP_003076098.1 CDS can NC_013008.1 146361 147023 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(146361..147023) Escherichia coli O157:H7 str. TW14359 8214693 YP_003076099.1 CDS yadG NC_013008.1 147132 148058 D ABC transporter ATP-binding protein 147132..148058 Escherichia coli O157:H7 str. TW14359 8214694 YP_003076100.1 CDS yadH NC_013008.1 148055 148825 D ABC transporter membrane protein 148055..148825 Escherichia coli O157:H7 str. TW14359 8214695 YP_003076101.1 CDS yadI NC_013008.1 148930 149370 D PTS Enzyme IIA 148930..149370 Escherichia coli O157:H7 str. TW14359 8214696 YP_003076102.1 CDS yadE NC_013008.1 149434 150663 D polysaccharide deacetylase lipoprotein 149434..150663 Escherichia coli O157:H7 str. TW14359 8214697 YP_003076103.1 CDS panD NC_013008.1 150667 151047 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(150667..151047) Escherichia coli O157:H7 str. TW14359 8214698 YP_003076104.1 CDS yadD NC_013008.1 151321 152217 D transposase 151321..152217 Escherichia coli O157:H7 str. TW14359 8214699 YP_003076105.1 CDS panC NC_013008.1 152516 153367 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(152516..153367) Escherichia coli O157:H7 str. TW14359 8214700 YP_003076106.1 CDS panB NC_013008.1 153379 154173 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(153379..154173) Escherichia coli O157:H7 str. TW14359 8214701 YP_003076107.1 CDS yadC NC_013008.1 154308 155417 R fimbrial protein complement(154308..155417) Escherichia coli O157:H7 str. TW14359 8214702 YP_003076108.1 CDS yadK NC_013008.1 155429 156019 R fimbrial protein complement(155429..156019) Escherichia coli O157:H7 str. TW14359 8214703 YP_003076109.1 CDS yadL NC_013008.1 156040 156645 R fimbrial protein complement(156040..156645) Escherichia coli O157:H7 str. TW14359 8214704 YP_003076110.1 CDS yadM NC_013008.1 156660 157220 R fimbrial protein complement(156660..157220) Escherichia coli O157:H7 str. TW14359 8214705 YP_003076111.1 CDS htrE NC_013008.1 157222 159822 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(157222..159822) Escherichia coli O157:H7 str. TW14359 8214706 YP_003076112.1 CDS ECSP_0141 NC_013008.1 159864 160589 R chaperone protein EcpD complement(159864..160589) Escherichia coli O157:H7 str. TW14359 8214707 YP_003076113.1 CDS yadN NC_013008.1 160676 161281 R fimbrial protein complement(160676..161281) Escherichia coli O157:H7 str. TW14359 8214708 YP_003076114.1 CDS folK NC_013008.1 161553 162035 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(161553..162035) Escherichia coli O157:H7 str. TW14359 8214709 YP_003076115.1 CDS pcnB NC_013008.1 162032 163429 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase complement(162032..163429) Escherichia coli O157:H7 str. TW14359 8214710 YP_003076116.1 CDS yadB NC_013008.1 163489 164415 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(163489..164415) Escherichia coli O157:H7 str. TW14359 8214711 YP_003076117.1 CDS dksA NC_013008.1 164452 164907 R RNA polymerase-binding transcription factor complement(164452..164907) Escherichia coli O157:H7 str. TW14359 8214712 YP_003076118.1 CDS sfsA NC_013008.1 165085 165789 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(165085..165789) Escherichia coli O157:H7 str. TW14359 8214713 YP_003076119.1 CDS ligT NC_013008.1 165804 166334 R 2'-5' RNA ligase complement(165804..166334) Escherichia coli O157:H7 str. TW14359 8214714 YP_003076120.1 CDS hrpB NC_013008.1 166408 168837 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 166408..168837 Escherichia coli O157:H7 str. TW14359 8214715 YP_003076121.1 CDS mrcB NC_013008.1 169033 171567 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 169033..171567 Escherichia coli O157:H7 str. TW14359 8214716 YP_003076122.1 CDS fhuA NC_013008.1 171787 174030 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 171787..174030 Escherichia coli O157:H7 str. TW14359 8214717 YP_003076123.1 CDS fhuC NC_013008.1 174081 174878 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 174081..174878 Escherichia coli O157:H7 str. TW14359 8214718 YP_003076124.1 CDS fhuD NC_013008.1 174878 175768 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 174878..175768 Escherichia coli O157:H7 str. TW14359 8214719 YP_003076125.1 CDS fhuB NC_013008.1 175765 177747 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 175765..177747 Escherichia coli O157:H7 str. TW14359 8214720 YP_003076126.1 CDS hemL NC_013008.1 177782 179062 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(177782..179062) Escherichia coli O157:H7 str. TW14359 8214721 YP_003076127.1 CDS clcA NC_013008.1 179287 180708 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 179287..180708 Escherichia coli O157:H7 str. TW14359 8214722 YP_003076128.1 CDS yadR NC_013008.1 180790 181134 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 180790..181134 Escherichia coli O157:H7 str. TW14359 8214723 YP_003076129.1 CDS yadS NC_013008.1 181181 181804 R hypothetical protein complement(181181..181804) Escherichia coli O157:H7 str. TW14359 8214724 YP_003076130.1 CDS btuF NC_013008.1 181842 182642 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(181842..182642) Escherichia coli O157:H7 str. TW14359 8214725 YP_003076131.1 CDS pfs NC_013008.1 182635 183333 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(182635..183333) Escherichia coli O157:H7 str. TW14359 8214726 YP_003076132.1 CDS dgt NC_013008.1 183417 184934 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 183417..184934 Escherichia coli O157:H7 str. TW14359 8214727 YP_003076133.1 CDS degP NC_013008.1 185064 186488 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 185064..186488 Escherichia coli O157:H7 str. TW14359 8214728 YP_003076134.1 CDS cdaR NC_013008.1 186643 187800 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 186643..187800 Escherichia coli O157:H7 str. TW14359 8214729 YP_003076135.1 CDS yaeH NC_013008.1 187889 188275 R hypothetical protein complement(187889..188275) Escherichia coli O157:H7 str. TW14359 8214730 YP_003076136.1 CDS dapD NC_013008.1 188590 189414 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(188590..189414) Escherichia coli O157:H7 str. TW14359 8214731 YP_003076137.1 CDS glnD NC_013008.1 189445 192117 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(189445..192117) Escherichia coli O157:H7 str. TW14359 8214732 YP_003076138.1 CDS map NC_013008.1 192179 192973 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(192179..192973) Escherichia coli O157:H7 str. TW14359 8214733 YP_003076139.1 CDS rpsB NC_013008.1 193341 194066 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 193341..194066 Escherichia coli O157:H7 str. TW14359 8214734 YP_003076140.1 CDS tsf NC_013008.1 194324 195175 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 194324..195175 Escherichia coli O157:H7 str. TW14359 8214735 YP_003076141.1 CDS pyrH NC_013008.1 195322 196047 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 195322..196047 Escherichia coli O157:H7 str. TW14359 8214736 YP_003076142.1 CDS frr NC_013008.1 196197 196754 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 196197..196754 Escherichia coli O157:H7 str. TW14359 8214737 YP_003076143.1 CDS dxr NC_013008.1 196846 198042 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 196846..198042 Escherichia coli O157:H7 str. TW14359 8214738 YP_003076144.1 CDS ispU NC_013008.1 198228 198989 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 198228..198989 Escherichia coli O157:H7 str. TW14359 8214739 YP_003076145.1 CDS cdsA NC_013008.1 199002 199859 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 199002..199859 Escherichia coli O157:H7 str. TW14359 8214740 YP_003076146.1 CDS rseP NC_013008.1 199871 201223 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 199871..201223 Escherichia coli O157:H7 str. TW14359 8214741 YP_003076147.1 CDS yaeT NC_013008.1 201253 203685 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 201253..203685 Escherichia coli O157:H7 str. TW14359 8214742 YP_003076148.1 CDS hlpA NC_013008.1 203806 204291 D periplasmic chaperone 203806..204291 Escherichia coli O157:H7 str. TW14359 8214743 YP_003076149.1 CDS lpxD NC_013008.1 204295 205320 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 204295..205320 Escherichia coli O157:H7 str. TW14359 8214744 YP_003076150.1 CDS fabZ NC_013008.1 205425 205880 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 205425..205880 Escherichia coli O157:H7 str. TW14359 8214745 YP_003076151.1 CDS lpxA NC_013008.1 205884 206672 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 205884..206672 Escherichia coli O157:H7 str. TW14359 8214746 YP_003076152.1 CDS lpxB NC_013008.1 206672 207820 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 206672..207820 Escherichia coli O157:H7 str. TW14359 8214747 YP_003076153.1 CDS rnhB NC_013008.1 207817 208413 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 207817..208413 Escherichia coli O157:H7 str. TW14359 8214748 YP_003076154.1 CDS dnaE NC_013008.1 208450 211932 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 208450..211932 Escherichia coli O157:H7 str. TW14359 8214749 YP_003076155.1 CDS accA NC_013008.1 211945 212904 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 211945..212904 Escherichia coli O157:H7 str. TW14359 8214750 YP_003076156.1 CDS ldcC NC_013008.1 213003 215144 D lysine decarboxylase 2 213003..215144 Escherichia coli O157:H7 str. TW14359 8214751 YP_003076157.1 CDS yaeR NC_013008.1 215201 215590 D hypothetical protein 215201..215590 Escherichia coli O157:H7 str. TW14359 8214752 YP_003076158.1 CDS tilS NC_013008.1 215655 216950 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 215655..216950 Escherichia coli O157:H7 str. TW14359 8214753 YP_003076159.1 CDS rof NC_013008.1 217003 217257 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(217003..217257) Escherichia coli O157:H7 str. TW14359 8214754 YP_003076160.1 CDS yaeQ NC_013008.1 217616 218161 D hypothetical protein 217616..218161 Escherichia coli O157:H7 str. TW14359 8214755 YP_003076161.1 CDS yaeJ NC_013008.1 218158 218568 D peptidyl-tRNA hydrolase domain-containing protein 218158..218568 Escherichia coli O157:H7 str. TW14359 8214756 YP_003076162.1 CDS nlpE NC_013008.1 218582 219292 D lipoprotein involved with copper homeostasis and adhesion 218582..219292 Escherichia coli O157:H7 str. TW14359 8214757 YP_003076163.1 CDS yaeF NC_013008.1 219492 220316 R hypothetical protein complement(219492..220316) Escherichia coli O157:H7 str. TW14359 8214758 YP_003076164.1 CDS proS NC_013008.1 220369 222087 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(220369..222087) Escherichia coli O157:H7 str. TW14359 8214759 YP_003076165.1 CDS yaeB NC_013008.1 222198 222905 R hypothetical protein complement(222198..222905) Escherichia coli O157:H7 str. TW14359 8214760 YP_003076166.1 CDS rcsF NC_013008.1 222902 223306 R outer membrane lipoprotein complement(222902..223306) Escherichia coli O157:H7 str. TW14359 8214761 YP_003076167.1 CDS metQ NC_013008.1 223424 224239 R DL-methionine transporter substrate-binding subunit complement(223424..224239) Escherichia coli O157:H7 str. TW14359 8214762 YP_003076168.1 CDS metI NC_013008.1 224279 224932 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit complement(224279..224932) Escherichia coli O157:H7 str. TW14359 8214763 YP_003076169.1 CDS metN NC_013008.1 224925 225956 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(224925..225956) Escherichia coli O157:H7 str. TW14359 8214764 YP_003076170.1 CDS gmhB NC_013008.1 226144 226719 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 226144..226719 Escherichia coli O157:H7 str. TW14359 8214765 YP_003076171.1 CDS dkgB NC_013008.1 232479 233282 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 232479..233282 Escherichia coli O157:H7 str. TW14359 8214772 YP_003076172.1 CDS yafC NC_013008.1 233279 234193 R DNA-binding transcriptional regulator complement(233279..234193) Escherichia coli O157:H7 str. TW14359 8214773 YP_003076173.1 CDS yafD NC_013008.1 234434 235234 D hypothetical protein 234434..235234 Escherichia coli O157:H7 str. TW14359 8214774 YP_003076174.1 CDS yafE NC_013008.1 235312 236082 D SAM-dependent methyltransferase 235312..236082 Escherichia coli O157:H7 str. TW14359 8214775 YP_003076175.1 CDS mltD NC_013008.1 236130 237488 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(236130..237488) Escherichia coli O157:H7 str. TW14359 8214776 YP_003076176.1 CDS gloB NC_013008.1 237560 238315 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(237560..238315) Escherichia coli O157:H7 str. TW14359 8214777 YP_003076177.1 CDS yafS NC_013008.1 238349 239071 D S-adenosyl-L-methionine-dependent methyltransferase 238349..239071 Escherichia coli O157:H7 str. TW14359 8214778 YP_003076178.1 CDS rnhA NC_013008.1 239068 239535 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(239068..239535) Escherichia coli O157:H7 str. TW14359 8214779 YP_003076179.1 CDS dnaQ NC_013008.1 239600 240331 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 239600..240331 Escherichia coli O157:H7 str. TW14359 8214780 YP_003076180.1 CDS yafT NC_013008.1 240869 241669 D aminopeptidase 240869..241669 Escherichia coli O157:H7 str. TW14359 8214782 YP_003076181.1 CDS ECSP_0217 NC_013008.1 241854 242150 R hypothetical protein complement(241854..242150) Escherichia coli O157:H7 str. TW14359 8214783 YP_003076182.1 CDS ECSP_0218 NC_013008.1 242147 242602 R hypothetical protein complement(242147..242602) Escherichia coli O157:H7 str. TW14359 8214784 YP_003076183.1 CDS ECSP_0219 NC_013008.1 242599 243195 R hypothetical protein complement(242599..243195) Escherichia coli O157:H7 str. TW14359 8214785 YP_003076184.1 CDS ECSP_0220 NC_013008.1 243305 243496 R hypothetical protein complement(243305..243496) Escherichia coli O157:H7 str. TW14359 8214786 YP_003076185.1 CDS ECSP_0221 NC_013008.1 243517 243996 R hypothetical protein complement(243517..243996) Escherichia coli O157:H7 str. TW14359 8214787 YP_003076186.1 CDS ECSP_0222 NC_013008.1 243962 245461 R hypothetical protein complement(243962..245461) Escherichia coli O157:H7 str. TW14359 8214788 YP_003076187.1 CDS ECSP_0223 NC_013008.1 245382 248816 R macrophage toxin complement(245382..248816) Escherichia coli O157:H7 str. TW14359 8214789 YP_003076188.1 CDS ECSP_0224 NC_013008.1 248953 250365 R ImpA domain-containing protein complement(248953..250365) Escherichia coli O157:H7 str. TW14359 8214790 YP_003076189.1 CDS ECSP_0225 NC_013008.1 250370 251113 R hypothetical protein complement(250370..251113) Escherichia coli O157:H7 str. TW14359 8214791 YP_003076190.1 CDS clpV NC_013008.1 251110 253887 R Hsp100/Clp ATPase complement(251110..253887) Escherichia coli O157:H7 str. TW14359 8214792 YP_003076191.1 CDS ECSP_0227 NC_013008.1 253896 254657 R hypothetical protein complement(253896..254657) Escherichia coli O157:H7 str. TW14359 8214793 YP_003076192.1 CDS ECSP_0228 NC_013008.1 254662 255993 R hypothetical protein complement(254662..255993) Escherichia coli O157:H7 str. TW14359 8214794 YP_003076193.1 CDS ECSP_0229 NC_013008.1 255996 256520 R hypothetical protein complement(255996..256520) Escherichia coli O157:H7 str. TW14359 8214795 YP_003076194.1 CDS ECSP_0230 NC_013008.1 256517 257818 R hypothetical protein complement(256517..257818) Escherichia coli O157:H7 str. TW14359 8214796 YP_003076195.1 CDS ECSP_0231 NC_013008.1 257822 258904 R hypothetical protein complement(257822..258904) Escherichia coli O157:H7 str. TW14359 8214797 YP_003076196.1 CDS ECSP_0232 NC_013008.1 258868 260718 R hypothetical protein complement(258868..260718) Escherichia coli O157:H7 str. TW14359 8214798 YP_003076197.1 CDS ECSP_0233 NC_013008.1 260722 261135 R hypothetical protein complement(260722..261135) Escherichia coli O157:H7 str. TW14359 8214799 YP_003076198.1 CDS ECSP_0234 NC_013008.1 261226 262617 R hypothetical protein complement(261226..262617) Escherichia coli O157:H7 str. TW14359 8214800 YP_003076199.1 CDS ECSP_0235 NC_013008.1 262668 262892 R hypothetical protein complement(262668..262892) Escherichia coli O157:H7 str. TW14359 8214801 YP_003076200.1 CDS ECSP_0236 NC_013008.1 262927 263427 R hypothetical protein complement(262927..263427) Escherichia coli O157:H7 str. TW14359 8214802 YP_003076201.1 CDS ECSP_0237 NC_013008.1 263854 263997 D hypothetical protein 263854..263997 Escherichia coli O157:H7 str. TW14359 8214803 YP_003076202.1 CDS ECSP_0238 NC_013008.1 264124 264642 D hypothetical protein 264124..264642 Escherichia coli O157:H7 str. TW14359 8214804 YP_003076203.1 CDS ECSP_0239 NC_013008.1 264675 264812 D hypothetical protein 264675..264812 Escherichia coli O157:H7 str. TW14359 8214805 YP_003076204.1 CDS ECSP_0240 NC_013008.1 264852 266993 D hypothetical protein 264852..266993 Escherichia coli O157:H7 str. TW14359 8214806 YP_003076205.1 CDS ECSP_0241 NC_013008.1 267069 271301 D hypothetical protein 267069..271301 Escherichia coli O157:H7 str. TW14359 8214807 YP_003076206.1 CDS ECSP_0242 NC_013008.1 271408 272157 D ankyrin repeat containing virulence factor 271408..272157 Escherichia coli O157:H7 str. TW14359 8214808 YP_003076207.1 CDS ECSP_0243 NC_013008.1 272339 273847 D RhsG core protein 272339..273847 Escherichia coli O157:H7 str. TW14359 8214809 YP_003076208.1 CDS ECSP_0244 NC_013008.1 273850 274467 D hypothetical protein 273850..274467 Escherichia coli O157:H7 str. TW14359 8214810 YP_003076209.1 CDS ECSP_0245 NC_013008.1 274470 274616 R hypothetical protein complement(274470..274616) Escherichia coli O157:H7 str. TW14359 8214811 YP_003076210.1 CDS ECSP_0246 NC_013008.1 274806 275105 D hypothetical protein 274806..275105 Escherichia coli O157:H7 str. TW14359 8214812 YP_003076211.1 CDS ECSP_0247 NC_013008.1 275213 276349 D transposase 275213..276349 Escherichia coli O157:H7 str. TW14359 8214813 YP_003076212.1 CDS ECSP_0248 NC_013008.1 276352 278112 D hypothetical protein 276352..278112 Escherichia coli O157:H7 str. TW14359 8214814 YP_003076213.1 CDS ECSP_0249 NC_013008.1 278314 278577 D hypothetical protein 278314..278577 Escherichia coli O157:H7 str. TW14359 8214815 YP_003076214.1 CDS ECSP_0250 NC_013008.1 278758 279930 D hypothetical protein 278758..279930 Escherichia coli O157:H7 str. TW14359 8214816 YP_003076215.1 CDS yafV NC_013008.1 280048 280818 R hypothetical protein complement(280048..280818) Escherichia coli O157:H7 str. TW14359 8214817 YP_003076216.1 CDS ivy NC_013008.1 280972 281445 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 280972..281445 Escherichia coli O157:H7 str. TW14359 8214818 YP_003076217.1 CDS fadE NC_013008.1 281488 283932 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(281488..283932) Escherichia coli O157:H7 str. TW14359 8214819 YP_003076218.1 CDS gmhA NC_013008.1 284172 284750 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 284172..284750 Escherichia coli O157:H7 str. TW14359 8214820 YP_003076219.1 CDS yafJ NC_013008.1 284855 285622 D amidotransfease 284855..285622 Escherichia coli O157:H7 str. TW14359 8214821 YP_003076220.1 CDS yafK NC_013008.1 285593 286333 R hypothetical protein complement(285593..286333) Escherichia coli O157:H7 str. TW14359 8214822 YP_003076221.1 CDS ECSP_0257 NC_013008.1 286489 286749 R hypothetical protein complement(286489..286749) Escherichia coli O157:H7 str. TW14359 8214823 YP_003076222.1 CDS dinJ NC_013008.1 286768 287028 R antitoxin of YafQ-DinJ toxin-antitoxin system complement(286768..287028) Escherichia coli O157:H7 str. TW14359 8214824 YP_003076223.1 CDS yafL NC_013008.1 287238 287987 D lipoprotein and C40 family peptidase 287238..287987 Escherichia coli O157:H7 str. TW14359 8214825 YP_003076224.1 CDS yafM NC_013008.1 288163 288459 D hypothetical protein 288163..288459 Escherichia coli O157:H7 str. TW14359 8214826 YP_003076225.1 CDS ECSP_0262 NC_013008.1 288678 288797 D hypothetical protein 288678..288797 Escherichia coli O157:H7 str. TW14359 8214828 YP_003076226.1 CDS ECSP_0263 NC_013008.1 288805 290544 R Flagellar component complement(288805..290544) Escherichia coli O157:H7 str. TW14359 8214829 YP_003076227.1 CDS ECSP_0264 NC_013008.1 290504 291274 D hypothetical protein 290504..291274 Escherichia coli O157:H7 str. TW14359 8214830 YP_003076228.1 CDS dinB NC_013008.1 291345 292400 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 291345..292400 Escherichia coli O157:H7 str. TW14359 8214831 YP_003076229.1 CDS yafN NC_013008.1 292452 292745 D antitoxin of the YafO-YafN toxin-antitoxin system 292452..292745 Escherichia coli O157:H7 str. TW14359 8214832 YP_003076230.1 CDS yafO NC_013008.1 292748 293146 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 292748..293146 Escherichia coli O157:H7 str. TW14359 8214833 YP_003076231.1 CDS yafP NC_013008.1 293156 293608 D hypothetical protein 293156..293608 Escherichia coli O157:H7 str. TW14359 8214834 YP_003076232.1 CDS ECSP_0269 NC_013008.1 293927 294181 D hypothetical protein 293927..294181 Escherichia coli O157:H7 str. TW14359 8214835 YP_003076233.1 CDS prfH NC_013008.1 294150 294650 D similar to release factor 1 and 2; peptide chain release factor-like protein 294150..294650 Escherichia coli O157:H7 str. TW14359 8214836 YP_003076234.1 CDS pepD NC_013008.1 294707 296164 R aminoacyl-histidine dipeptidase complement(294707..296164) Escherichia coli O157:H7 str. TW14359 8214837 YP_003076235.1 CDS gpt NC_013008.1 296425 296883 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 296425..296883 Escherichia coli O157:H7 str. TW14359 8214838 YP_003076236.1 CDS frsA NC_013008.1 296975 298219 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 296975..298219 Escherichia coli O157:H7 str. TW14359 8214839 YP_003076237.1 CDS crl NC_013008.1 298277 298678 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 298277..298678 Escherichia coli O157:H7 str. TW14359 8214840 YP_003076238.1 CDS phoE NC_013008.1 298717 299772 R outer membrane phosphoporin protein E complement(298717..299772) Escherichia coli O157:H7 str. TW14359 8214841 YP_003076239.1 CDS proB NC_013008.1 300060 301163 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 300060..301163 Escherichia coli O157:H7 str. TW14359 8214842 YP_003076240.1 CDS proA NC_013008.1 301175 302428 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 301175..302428 Escherichia coli O157:H7 str. TW14359 8214843 YP_003076241.1 CDS intH NC_013008.1 302633 303607 R integrase for prophage CP-933H complement(302633..303607) Escherichia coli O157:H7 str. TW14359 8214845 YP_003076242.1 CDS ECSP_0280 NC_013008.1 304070 304960 R transposase complement(304070..304960) Escherichia coli O157:H7 str. TW14359 8214846 YP_003076243.1 CDS ECSP_0281 NC_013008.1 304957 305283 R transposase complement(304957..305283) Escherichia coli O157:H7 str. TW14359 8214847 YP_003076244.1 CDS ECSP_0282 NC_013008.1 305309 305692 R hypothetical protein complement(305309..305692) Escherichia coli O157:H7 str. TW14359 8214848 YP_003076245.1 CDS ECSP_0283 NC_013008.1 305820 306533 R cI repressor protein for prophage CP-933H complement(305820..306533) Escherichia coli O157:H7 str. TW14359 8214849 YP_003076246.1 CDS ECSP_0284 NC_013008.1 306634 306834 D regulatory protein cro 306634..306834 Escherichia coli O157:H7 str. TW14359 8214850 YP_003076247.1 CDS ECSP_0285 NC_013008.1 306953 307246 D cII antiterminator protein for prophage CP-933H 306953..307246 Escherichia coli O157:H7 str. TW14359 8214851 YP_003076248.1 CDS ECSP_0287 NC_013008.1 308198 308509 D replication protein P for prophage CP-933H 308198..308509 Escherichia coli O157:H7 str. TW14359 8214853 YP_003076249.1 CDS ECSP_0288 NC_013008.1 308509 309303 D tail fiber protein from prophage CP-933H 308509..309303 Escherichia coli O157:H7 str. TW14359 8214854 YP_003076250.1 CDS ECSP_0289 NC_013008.1 309303 309896 D hypothetical protein 309303..309896 Escherichia coli O157:H7 str. TW14359 8214855 YP_003076251.1 CDS ECSP_0290 NC_013008.1 309868 310320 R hypothetical protein complement(309868..310320) Escherichia coli O157:H7 str. TW14359 8214856 YP_003076252.1 CDS ECSP_0291 NC_013008.1 310332 310766 R hypothetical protein complement(310332..310766) Escherichia coli O157:H7 str. TW14359 8214857 YP_003076253.1 CDS pinH NC_013008.1 310772 311326 D DNA invertase from prophage CP-933H 310772..311326 Escherichia coli O157:H7 str. TW14359 8214858 YP_003076254.1 CDS ECSP_0293 NC_013008.1 311384 312157 R hypothetical protein complement(311384..312157) Escherichia coli O157:H7 str. TW14359 8214859 YP_003076255.1 CDS ECSP_0294 NC_013008.1 312980 313723 D AraC family transcriptional regulator 312980..313723 Escherichia coli O157:H7 str. TW14359 8214860 YP_003076256.1 CDS ECSP_0295 NC_013008.1 313765 314130 R hypothetical protein complement(313765..314130) Escherichia coli O157:H7 str. TW14359 8214861 YP_003076257.1 CDS ECSP_0296 NC_013008.1 315248 316138 R transposase complement(315248..316138) Escherichia coli O157:H7 str. TW14359 8214862 YP_003076258.1 CDS ECSP_0297 NC_013008.1 316135 316461 R transposase complement(316135..316461) Escherichia coli O157:H7 str. TW14359 8214863 YP_003076259.1 CDS ECSP_0300 NC_013008.1 318190 318648 D hypothetical protein 318190..318648 Escherichia coli O157:H7 str. TW14359 8214866 YP_003076260.1 CDS ECSP_0301 NC_013008.1 318641 319273 D hypothetical protein 318641..319273 Escherichia coli O157:H7 str. TW14359 8214867 YP_003076261.1 CDS ECSP_0302 NC_013008.1 319304 319693 D hypothetical protein 319304..319693 Escherichia coli O157:H7 str. TW14359 8214868 YP_003076262.1 CDS ECSP_0303 NC_013008.1 319893 320459 D hypothetical protein 319893..320459 Escherichia coli O157:H7 str. TW14359 8214869 YP_003076263.1 CDS ECSP_0304 NC_013008.1 320869 321141 R activator encoded in prophage CP-933I complement(320869..321141) Escherichia coli O157:H7 str. TW14359 8214870 YP_003076264.1 CDS psuI NC_013008.1 321147 321698 R polarity suppression protein encoded in CP-933I complement(321147..321698) Escherichia coli O157:H7 str. TW14359 8214871 YP_003076265.1 CDS sidI NC_013008.1 321695 322447 R capsid morphogenesis protein encoded in CP-933I complement(321695..322447) Escherichia coli O157:H7 str. TW14359 8214872 YP_003076266.1 CDS ECSP_0307 NC_013008.1 322850 323020 D hypothetical protein 322850..323020 Escherichia coli O157:H7 str. TW14359 8214873 YP_003076267.1 CDS ECSP_0308 NC_013008.1 323381 323641 D regulatory protein encoded in prophage CP-933I 323381..323641 Escherichia coli O157:H7 str. TW14359 8214874 YP_003076268.1 CDS ECSP_0309 NC_013008.1 323638 324195 D regulator encoded in prophage CP-933I 323638..324195 Escherichia coli O157:H7 str. TW14359 8214875 YP_003076269.1 CDS ECSP_0310 NC_013008.1 324413 324736 D hypothetical protein 324413..324736 Escherichia coli O157:H7 str. TW14359 8214876 YP_003076270.1 CDS ECSP_0311 NC_013008.1 324750 327083 D alpha replication protein of prophage CP-933I 324750..327083 Escherichia coli O157:H7 str. TW14359 8214877 YP_003076271.1 CDS ECSP_0312 NC_013008.1 327216 328172 R hypothetical protein complement(327216..328172) Escherichia coli O157:H7 str. TW14359 8214878 YP_003076272.1 CDS ECSP_0313 NC_013008.1 328848 329747 R LysR family transcriptional regulator complement(328848..329747) Escherichia coli O157:H7 str. TW14359 8214879 YP_003076273.1 CDS ECSP_0314 NC_013008.1 329846 330568 D oxidoreductase 329846..330568 Escherichia coli O157:H7 str. TW14359 8214880 YP_003076274.1 CDS ECSP_0315 NC_013008.1 330735 331013 D hypothetical protein 330735..331013 Escherichia coli O157:H7 str. TW14359 8214881 YP_003076275.1 CDS ECSP_0316 NC_013008.1 331288 331437 D hypothetical protein 331288..331437 Escherichia coli O157:H7 str. TW14359 8214882 YP_003076276.1 CDS ECSP_0317 NC_013008.1 331716 332600 R LysR family transcriptional regulator complement(331716..332600) Escherichia coli O157:H7 str. TW14359 8214883 YP_003076277.1 CDS ECSP_0318 NC_013008.1 332864 333922 D hypothetical protein 332864..333922 Escherichia coli O157:H7 str. TW14359 8214884 YP_003076278.1 CDS ECSP_0319 NC_013008.1 333998 335191 D transcriptional regulator 333998..335191 Escherichia coli O157:H7 str. TW14359 8214885 YP_003076279.1 CDS yagQ NC_013008.1 335370 336326 R hypothetical protein complement(335370..336326) Escherichia coli O157:H7 str. TW14359 8214886 YP_003076280.1 CDS yagR NC_013008.1 336336 338534 R oxidoreductase complement(336336..338534) Escherichia coli O157:H7 str. TW14359 8214887 YP_003076281.1 CDS yagS NC_013008.1 338531 339487 R oxidoreductase complement(338531..339487) Escherichia coli O157:H7 str. TW14359 8214888 YP_003076282.1 CDS yagT NC_013008.1 339484 340173 R xanthine dehydrogenase iron-sulfur-binding subunit complement(339484..340173) Escherichia coli O157:H7 str. TW14359 8214889 YP_003076283.1 CDS yagU NC_013008.1 340591 341205 D hypothetical protein 340591..341205 Escherichia coli O157:H7 str. TW14359 8214890 YP_003076284.1 CDS ykgJ NC_013008.1 341453 341782 R ferredoxin complement(341453..341782) Escherichia coli O157:H7 str. TW14359 8214891 YP_003076285.1 CDS ecpE NC_013008.1 342095 342805 R chaperone complement(342095..342805) Escherichia coli O157:H7 str. TW14359 8214892 YP_003076286.1 CDS yagW NC_013008.1 342774 344417 R receptor complement(342774..344417) Escherichia coli O157:H7 str. TW14359 8214893 YP_003076287.1 CDS ecpC NC_013008.1 344407 346932 R usher protein complement(344407..346932) Escherichia coli O157:H7 str. TW14359 8214894 YP_003076288.1 CDS ecpB NC_013008.1 346958 347626 R chaperone complement(346958..347626) Escherichia coli O157:H7 str. TW14359 8214895 YP_003076289.1 CDS ecpA NC_013008.1 347684 348271 R Mat fimbrillin complement(347684..348271) Escherichia coli O157:H7 str. TW14359 8214896 YP_003076290.1 CDS ecpR NC_013008.1 348346 348936 R regulator complement(348346..348936) Escherichia coli O157:H7 str. TW14359 8214897 YP_003076291.1 CDS ECSP_0332 NC_013008.1 349135 349230 R hypothetical protein complement(349135..349230) Escherichia coli O157:H7 str. TW14359 8214898 YP_003076292.1 CDS ECSP_0333 NC_013008.1 349342 349566 R hypothetical protein complement(349342..349566) Escherichia coli O157:H7 str. TW14359 8214899 YP_003076293.1 CDS ykgL NC_013008.1 349713 349904 D hypothetical protein 349713..349904 Escherichia coli O157:H7 str. TW14359 8214900 YP_003076294.1 CDS rpmJ NC_013008.1 349974 350114 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(349974..350114) Escherichia coli O157:H7 str. TW14359 8214901 YP_003076295.1 CDS rpmE2 NC_013008.1 350114 350377 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(350114..350377) Escherichia coli O157:H7 str. TW14359 8214902 YP_003076296.1 CDS ECSP_0337 NC_013008.1 350620 351021 D hypothetical protein 350620..351021 Escherichia coli O157:H7 str. TW14359 8214903 YP_003076297.1 CDS ECSP_0338 NC_013008.1 351018 351365 D transposase ISEc8 351018..351365 Escherichia coli O157:H7 str. TW14359 8214904 YP_003076298.1 CDS ECSP_0339 NC_013008.1 351415 352953 D transposase ISEc8 351415..352953 Escherichia coli O157:H7 str. TW14359 8214905 YP_003076299.1 CDS ECSP_0340 NC_013008.1 353765 354907 R oxidoreductase complement(353765..354907) Escherichia coli O157:H7 str. TW14359 8214906 YP_003076300.1 CDS ECSP_0341 NC_013008.1 355142 356062 R hypothetical protein complement(355142..356062) Escherichia coli O157:H7 str. TW14359 8214907 YP_003076301.1 CDS ECSP_0342 NC_013008.1 356156 357145 D LysR family transcriptional regulator 356156..357145 Escherichia coli O157:H7 str. TW14359 8214908 YP_003076302.1 CDS ECSP_0343 NC_013008.1 357433 357789 R hypothetical protein complement(357433..357789) Escherichia coli O157:H7 str. TW14359 8214909 YP_003076303.1 CDS ECSP_0344 NC_013008.1 357820 357948 D hypothetical protein 357820..357948 Escherichia coli O157:H7 str. TW14359 8214910 YP_003076304.1 CDS ECSP_0345 NC_013008.1 357982 358557 R hypothetical protein complement(357982..358557) Escherichia coli O157:H7 str. TW14359 8214911 YP_003076305.1 CDS eaeH NC_013008.1 359123 363376 D adhesin 359123..363376 Escherichia coli O157:H7 str. TW14359 8214912 YP_003076306.1 CDS ykgA NC_013008.1 363497 364387 R DNA-binding transcriptional regulator complement(363497..364387) Escherichia coli O157:H7 str. TW14359 8214913 YP_003076307.1 CDS ECSP_0348 NC_013008.1 364603 365472 D dehydrogenase 364603..365472 Escherichia coli O157:H7 str. TW14359 8214914 YP_003076308.1 CDS ykgB NC_013008.1 365632 366225 R hypothetical protein complement(365632..366225) Escherichia coli O157:H7 str. TW14359 8214915 YP_003076309.1 CDS ykgI NC_013008.1 366237 366473 R hypothetical protein complement(366237..366473) Escherichia coli O157:H7 str. TW14359 8214916 YP_003076310.1 CDS ykgC NC_013008.1 366582 367907 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(366582..367907) Escherichia coli O157:H7 str. TW14359 8214917 YP_003076311.1 CDS ykgD NC_013008.1 368133 368987 D DNA-binding transcriptional regulator 368133..368987 Escherichia coli O157:H7 str. TW14359 8214918 YP_003076312.1 CDS ykgE NC_013008.1 369514 370233 D oxidoreductase 369514..370233 Escherichia coli O157:H7 str. TW14359 8214919 YP_003076313.1 CDS ykgF NC_013008.1 370244 371671 D amino acid dehydrogenase 370244..371671 Escherichia coli O157:H7 str. TW14359 8214920 YP_003076314.1 CDS ykgG NC_013008.1 371664 372359 D transporter 371664..372359 Escherichia coli O157:H7 str. TW14359 8214921 YP_003076315.1 CDS ECSP_0356 NC_013008.1 372433 372630 R hypothetical protein complement(372433..372630) Escherichia coli O157:H7 str. TW14359 8214922 YP_003076316.1 CDS ECSP_0359 NC_013008.1 373618 374712 R autotransporter complement(373618..374712) Escherichia coli O157:H7 str. TW14359 8214925 YP_003076317.1 CDS ECSP_0360 NC_013008.1 374754 375515 R hypothetical protein complement(374754..375515) Escherichia coli O157:H7 str. TW14359 8214926 YP_003076318.1 CDS ECSP_0361 NC_013008.1 375669 376253 R hypothetical protein complement(375669..376253) Escherichia coli O157:H7 str. TW14359 8214927 YP_003076319.1 CDS ECSP_0362 NC_013008.1 376345 376482 R hypothetical protein complement(376345..376482) Escherichia coli O157:H7 str. TW14359 8214928 YP_003076320.1 CDS ECSP_0364 NC_013008.1 377599 377733 D hypothetical protein 377599..377733 Escherichia coli O157:H7 str. TW14359 8214930 YP_003076321.1 CDS ECSP_0365 NC_013008.1 378162 378413 D hypothetical protein 378162..378413 Escherichia coli O157:H7 str. TW14359 8214931 YP_003076322.1 CDS betA NC_013008.1 378415 380103 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(378415..380103) Escherichia coli O157:H7 str. TW14359 8214932 YP_003076323.1 CDS betB NC_013008.1 380117 381589 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(380117..381589) Escherichia coli O157:H7 str. TW14359 8214933 YP_003076324.1 CDS betI NC_013008.1 381603 382190 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(381603..382190) Escherichia coli O157:H7 str. TW14359 8214934 YP_003076325.1 CDS betT NC_013008.1 382319 384352 D proton-motive-force-driven choline transporter; choline transport protein BetT 382319..384352 Escherichia coli O157:H7 str. TW14359 8214935 YP_003076326.1 CDS ECSP_0370 NC_013008.1 384860 388909 D beta-barrel outer membrane protein 384860..388909 Escherichia coli O157:H7 str. TW14359 8214936 YP_003076327.1 CDS yahA NC_013008.1 389051 390139 D DNA-binding transcriptional regulator 389051..390139 Escherichia coli O157:H7 str. TW14359 8214937 YP_003076328.1 CDS ECSP_0373 NC_013008.1 391204 391506 R hypothetical protein complement(391204..391506) Escherichia coli O157:H7 str. TW14359 8214939 YP_003076329.1 CDS yahD NC_013008.1 391969 392574 D transcriptional regulator with ankyrin domain 391969..392574 Escherichia coli O157:H7 str. TW14359 8214940 YP_003076330.1 CDS yahE NC_013008.1 392614 393477 D hypothetical protein 392614..393477 Escherichia coli O157:H7 str. TW14359 8214941 YP_003076331.1 CDS yahF NC_013008.1 393467 395014 D acyl-CoA synthetase with NAD(P)-binding domain and succinyl-CoA synthetase domain 393467..395014 Escherichia coli O157:H7 str. TW14359 8214942 YP_003076332.1 CDS yahG NC_013008.1 395014 396432 D hypothetical protein 395014..396432 Escherichia coli O157:H7 str. TW14359 8214943 YP_003076333.1 CDS ECSP_0378 NC_013008.1 396451 396915 D hypothetical protein 396451..396915 Escherichia coli O157:H7 str. TW14359 8214944 YP_003076334.1 CDS yahI NC_013008.1 396947 397897 D carbamate kinase 396947..397897 Escherichia coli O157:H7 str. TW14359 8214945 YP_003076335.1 CDS yahJ NC_013008.1 397907 399289 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 397907..399289 Escherichia coli O157:H7 str. TW14359 8214946 YP_003076336.1 CDS ECSP_0381 NC_013008.1 399588 399998 D hypothetical protein 399588..399998 Escherichia coli O157:H7 str. TW14359 8214947 YP_003076337.1 CDS ECSP_0382 NC_013008.1 400026 400127 R hypothetical protein complement(400026..400127) Escherichia coli O157:H7 str. TW14359 8214948 YP_003076338.1 CDS ECSP_0383 NC_013008.1 400249 401235 D periplasmic binding protein, substrate ribose 400249..401235 Escherichia coli O157:H7 str. TW14359 8214949 YP_003076339.1 CDS ECSP_0384 NC_013008.1 401284 402768 D carbohydrate uptake transporter-2 (CUT2) family protein 401284..402768 Escherichia coli O157:H7 str. TW14359 8214950 YP_003076340.1 CDS ECSP_0385 NC_013008.1 402761 403732 D permease component of transport system, probably ribose specific 402761..403732 Escherichia coli O157:H7 str. TW14359 8214951 YP_003076341.1 CDS ECSP_0386 NC_013008.1 403729 404685 D permease component of transport system, probably ribose specific 403729..404685 Escherichia coli O157:H7 str. TW14359 8214952 YP_003076342.1 CDS yahK NC_013008.1 404772 405821 D oxidoreductase 404772..405821 Escherichia coli O157:H7 str. TW14359 8214953 YP_003076343.1 CDS yahL NC_013008.1 406064 406879 D hypothetical protein 406064..406879 Escherichia coli O157:H7 str. TW14359 8214954 YP_003076344.1 CDS yahN NC_013008.1 407557 408228 R neutral amino-acid efflux system complement(407557..408228) Escherichia coli O157:H7 str. TW14359 8214956 YP_003076345.1 CDS yahO NC_013008.1 408375 408650 D hypothetical protein 408375..408650 Escherichia coli O157:H7 str. TW14359 8214957 YP_003076346.1 CDS prpR NC_013008.1 408748 410334 R DNA-binding transcriptional activator complement(408748..410334) Escherichia coli O157:H7 str. TW14359 8214958 YP_003076347.1 CDS prpB NC_013008.1 410573 411463 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 410573..411463 Escherichia coli O157:H7 str. TW14359 8214959 YP_003076348.1 CDS prpC NC_013008.1 411619 412788 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 411619..412788 Escherichia coli O157:H7 str. TW14359 8214960 YP_003076349.1 CDS prpD NC_013008.1 412822 414273 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 412822..414273 Escherichia coli O157:H7 str. TW14359 8214961 YP_003076350.1 CDS prpE NC_013008.1 414313 416199 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 414313..416199 Escherichia coli O157:H7 str. TW14359 8214962 YP_003076351.1 CDS ECSP_0397 NC_013008.1 416468 416746 R hypothetical protein complement(416468..416746) Escherichia coli O157:H7 str. TW14359 8214963 YP_003076352.1 CDS codB NC_013008.1 417093 418352 D cytosine permease 417093..418352 Escherichia coli O157:H7 str. TW14359 8214964 YP_003076353.1 CDS codA NC_013008.1 418342 419625 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 418342..419625 Escherichia coli O157:H7 str. TW14359 8214965 YP_003076354.1 CDS cynR NC_013008.1 419758 420657 R controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR complement(419758..420657) Escherichia coli O157:H7 str. TW14359 8214966 YP_003076355.1 CDS cynT NC_013008.1 420767 421426 D carbonic anhydrase 420767..421426 Escherichia coli O157:H7 str. TW14359 8214967 YP_003076356.1 CDS cynS NC_013008.1 421457 421927 D catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 421457..421927 Escherichia coli O157:H7 str. TW14359 8214968 YP_003076357.1 CDS cynX NC_013008.1 421960 423114 D MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; cyanate transporter 421960..423114 Escherichia coli O157:H7 str. TW14359 8214969 YP_003076358.1 CDS lacA NC_013008.1 423217 423828 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(423217..423828) Escherichia coli O157:H7 str. TW14359 8214970 YP_003076359.1 CDS lacY NC_013008.1 423894 425147 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(423894..425147) Escherichia coli O157:H7 str. TW14359 8214971 YP_003076360.1 CDS lacZ NC_013008.1 425199 428273 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(425199..428273) Escherichia coli O157:H7 str. TW14359 8214972 YP_003076361.1 CDS lacI NC_013008.1 428396 429478 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(428396..429478) Escherichia coli O157:H7 str. TW14359 8214973 YP_003076362.1 CDS ECSP_0408 NC_013008.1 429515 430468 R AraC family transcriptional regulator complement(429515..430468) Escherichia coli O157:H7 str. TW14359 8214974 YP_003076363.1 CDS ECSP_0409 NC_013008.1 430488 431264 R hypothetical protein complement(430488..431264) Escherichia coli O157:H7 str. TW14359 8214975 YP_003076364.1 CDS mhpR NC_013008.1 431379 432212 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR complement(431379..432212) Escherichia coli O157:H7 str. TW14359 8214976 YP_003076365.1 CDS mhpA NC_013008.1 432403 434067 D catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 432403..434067 Escherichia coli O157:H7 str. TW14359 8214977 YP_003076366.1 CDS mhpB NC_013008.1 434069 435013 D catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 434069..435013 Escherichia coli O157:H7 str. TW14359 8214978 YP_003076367.1 CDS mhpC NC_013008.1 435016 435897 D 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 435016..435897 Escherichia coli O157:H7 str. TW14359 8214979 YP_003076368.1 CDS mhpD NC_013008.1 435907 436716 D catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 435907..436716 Escherichia coli O157:H7 str. TW14359 8214980 YP_003076369.1 CDS mhpF NC_013008.1 436713 437663 D catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 436713..437663 Escherichia coli O157:H7 str. TW14359 8214981 YP_003076370.1 CDS mhpE NC_013008.1 437660 438673 D catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 437660..438673 Escherichia coli O157:H7 str. TW14359 8214982 YP_003076371.1 CDS mhpT NC_013008.1 438849 440060 D 3-hydroxyphenylpropionic transporter MhpT 438849..440060 Escherichia coli O157:H7 str. TW14359 8214983 YP_003076372.1 CDS yaiL NC_013008.1 440162 440701 D nucleoprotein/polynucleotide-associated enzyme 440162..440701 Escherichia coli O157:H7 str. TW14359 8214984 YP_003076373.1 CDS frmB NC_013008.1 440826 441659 R esterase complement(440826..441659) Escherichia coli O157:H7 str. TW14359 8214985 YP_003076374.1 CDS frmA NC_013008.1 441752 442861 R alcohol dehydrogenase complement(441752..442861) Escherichia coli O157:H7 str. TW14359 8214986 YP_003076375.1 CDS frmR NC_013008.1 442896 443171 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(442896..443171) Escherichia coli O157:H7 str. TW14359 8214987 YP_003076376.1 CDS fbpC NC_013008.1 443331 444377 R Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit complement(443331..444377) Escherichia coli O157:H7 str. TW14359 8214988 YP_003076377.1 CDS afuB NC_013008.1 444389 446467 R permease component of transport system for ferric iron complement(444389..446467) Escherichia coli O157:H7 str. TW14359 8214989 YP_003076378.1 CDS afuA NC_013008.1 446536 447567 R periplasmic ferric iron-binding protein complement(446536..447567) Escherichia coli O157:H7 str. TW14359 8214990 YP_003076379.1 CDS ECSP_0425 NC_013008.1 447564 448868 R permease; hexosephosphate transport complement(447564..448868) Escherichia coli O157:H7 str. TW14359 8214991 YP_003076380.1 CDS ECSP_0426 NC_013008.1 448953 450494 R sensor kinase; hexosephosphate transport complement(448953..450494) Escherichia coli O157:H7 str. TW14359 8214992 YP_003076381.1 CDS ECSP_0427 NC_013008.1 450494 451123 R response regulator; hexosephosphate transport complement(450494..451123) Escherichia coli O157:H7 str. TW14359 8214993 YP_003076382.1 CDS tauA NC_013008.1 451426 452388 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 451426..452388 Escherichia coli O157:H7 str. TW14359 8214994 YP_003076383.1 CDS tauB NC_013008.1 452401 453168 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 452401..453168 Escherichia coli O157:H7 str. TW14359 8214995 YP_003076384.1 CDS tauC NC_013008.1 453165 453992 D taurine transporter subunit 453165..453992 Escherichia coli O157:H7 str. TW14359 8214996 YP_003076385.1 CDS tauD NC_013008.1 453989 454840 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 453989..454840 Escherichia coli O157:H7 str. TW14359 8214997 YP_003076386.1 CDS hemB NC_013008.1 454947 455921 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(454947..455921) Escherichia coli O157:H7 str. TW14359 8214998 YP_003076387.1 CDS yaiV NC_013008.1 459463 460086 D DNA-binding transcriptional regulator 459463..460086 Escherichia coli O157:H7 str. TW14359 8215000 YP_003076388.1 CDS ampH NC_013008.1 460087 461244 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(460087..461244) Escherichia coli O157:H7 str. TW14359 8215001 YP_003076389.1 CDS ECSP_0436 NC_013008.1 461336 461458 R hypothetical protein complement(461336..461458) Escherichia coli O157:H7 str. TW14359 8215002 YP_003076390.1 CDS sbmA NC_013008.1 461596 462816 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 461596..462816 Escherichia coli O157:H7 str. TW14359 8215003 YP_003076391.1 CDS yaiW NC_013008.1 462829 463923 D DNA-binding transcriptional regulator 462829..463923 Escherichia coli O157:H7 str. TW14359 8215004 YP_003076392.1 CDS yaiY NC_013008.1 463982 464290 R inner membrane protein complement(463982..464290) Escherichia coli O157:H7 str. TW14359 8215005 YP_003076393.1 CDS yaiZ NC_013008.1 464550 464762 D inner membrane protein 464550..464762 Escherichia coli O157:H7 str. TW14359 8215006 YP_003076394.1 CDS ddl NC_013008.1 464786 465880 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(464786..465880) Escherichia coli O157:H7 str. TW14359 8215007 YP_003076395.1 CDS ECSP_0442 NC_013008.1 465958 466161 D hypothetical protein 465958..466161 Escherichia coli O157:H7 str. TW14359 8215008 YP_003076396.1 CDS ECSP_0443 NC_013008.1 466175 466297 D hypothetical protein 466175..466297 Escherichia coli O157:H7 str. TW14359 8215009 YP_003076397.1 CDS iraP NC_013008.1 466343 466603 D hypothetical protein 466343..466603 Escherichia coli O157:H7 str. TW14359 8215010 YP_003076398.1 CDS phoA NC_013008.1 466704 468119 D alkaline phosphatase 466704..468119 Escherichia coli O157:H7 str. TW14359 8215011 YP_003076399.1 CDS psiF NC_013008.1 468238 468558 D hypothetical protein 468238..468558 Escherichia coli O157:H7 str. TW14359 8215012 YP_003076400.1 CDS adrA NC_013008.1 468660 469775 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 468660..469775 Escherichia coli O157:H7 str. TW14359 8215013 YP_003076401.1 CDS proC NC_013008.1 469792 470601 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(469792..470601) Escherichia coli O157:H7 str. TW14359 8215014 YP_003076402.1 CDS yaiI NC_013008.1 470721 471179 D hypothetical protein 470721..471179 Escherichia coli O157:H7 str. TW14359 8215015 YP_003076403.1 CDS aroL NC_013008.1 471362 471886 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 471362..471886 Escherichia coli O157:H7 str. TW14359 8215016 YP_003076404.1 CDS yaiA NC_013008.1 471936 472127 D hypothetical protein 471936..472127 Escherichia coli O157:H7 str. TW14359 8215017 YP_003076405.1 CDS aroM NC_013008.1 472385 473062 D hypothetical protein 472385..473062 Escherichia coli O157:H7 str. TW14359 8215018 YP_003076406.1 CDS yaiE NC_013008.1 473134 473418 D hypothetical protein 473134..473418 Escherichia coli O157:H7 str. TW14359 8215019 YP_003076407.1 CDS ykiA NC_013008.1 475560 475841 D hypothetical protein 475560..475841 Escherichia coli O157:H7 str. TW14359 8215020 YP_003076408.1 CDS ECSP_0455 NC_013008.1 475838 476287 D hypothetical protein 475838..476287 Escherichia coli O157:H7 str. TW14359 8215021 YP_003076409.1 CDS rdgC NC_013008.1 476372 477283 R Required for efficient pilin antigenic variation; recombination associated protein complement(476372..477283) Escherichia coli O157:H7 str. TW14359 8215022 YP_003076410.1 CDS mak NC_013008.1 477408 478316 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 477408..478316 Escherichia coli O157:H7 str. TW14359 8215023 YP_003076411.1 CDS araJ NC_013008.1 478459 479643 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(478459..479643) Escherichia coli O157:H7 str. TW14359 8215024 YP_003076412.1 CDS sbcC NC_013008.1 479769 482912 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC complement(479769..482912) Escherichia coli O157:H7 str. TW14359 8215025 YP_003076413.1 CDS sbcD NC_013008.1 482909 484111 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD complement(482909..484111) Escherichia coli O157:H7 str. TW14359 8215026 YP_003076414.1 CDS phoB NC_013008.1 484301 484990 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 484301..484990 Escherichia coli O157:H7 str. TW14359 8215027 YP_003076415.1 CDS phoR NC_013008.1 485048 486343 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 485048..486343 Escherichia coli O157:H7 str. TW14359 8215028 YP_003076416.1 CDS ECSP_0463 NC_013008.1 486354 486464 R hypothetical protein complement(486354..486464) Escherichia coli O157:H7 str. TW14359 8215029 YP_003076417.1 CDS ECSP_0464 NC_013008.1 486556 486705 R hypothetical protein complement(486556..486705) Escherichia coli O157:H7 str. TW14359 8215030 YP_003076418.1 CDS brnQ NC_013008.1 486750 488069 D branched chain amino acid transporter 486750..488069 Escherichia coli O157:H7 str. TW14359 8215031 YP_003076419.1 CDS proY NC_013008.1 488145 489518 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 488145..489518 Escherichia coli O157:H7 str. TW14359 8215032 YP_003076420.1 CDS malZ NC_013008.1 489674 491491 D maltodextrin glucosidase 489674..491491 Escherichia coli O157:H7 str. TW14359 8215033 YP_003076421.1 CDS ECSP_0468 NC_013008.1 491679 493124 D hypothetical protein 491679..493124 Escherichia coli O157:H7 str. TW14359 8215034 YP_003076422.1 CDS acpH NC_013008.1 493145 493726 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase complement(493145..493726) Escherichia coli O157:H7 str. TW14359 8215035 YP_003076423.1 CDS queA NC_013008.1 493819 494889 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 493819..494889 Escherichia coli O157:H7 str. TW14359 8215036 YP_003076424.1 CDS tgt NC_013008.1 494944 496071 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 494944..496071 Escherichia coli O157:H7 str. TW14359 8215037 YP_003076425.1 CDS yajC NC_013008.1 496094 496426 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 496094..496426 Escherichia coli O157:H7 str. TW14359 8215038 YP_003076426.1 CDS secD NC_013008.1 496454 498301 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 496454..498301 Escherichia coli O157:H7 str. TW14359 8215039 YP_003076427.1 CDS secF NC_013008.1 498312 499283 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 498312..499283 Escherichia coli O157:H7 str. TW14359 8215040 YP_003076428.1 CDS ECSP_0475 NC_013008.1 499435 499677 D hypothetical protein 499435..499677 Escherichia coli O157:H7 str. TW14359 8215041 YP_003076429.1 CDS ECSP_0476 NC_013008.1 499670 499951 D hypothetical protein 499670..499951 Escherichia coli O157:H7 str. TW14359 8215042 YP_003076430.1 CDS yajD NC_013008.1 500039 500386 D hypothetical protein 500039..500386 Escherichia coli O157:H7 str. TW14359 8215043 YP_003076431.1 CDS tsx NC_013008.1 500563 501447 R nucleoside channel phage T6/colicin K receptor complement(500563..501447) Escherichia coli O157:H7 str. TW14359 8215044 YP_003076432.1 CDS yajI NC_013008.1 501746 502285 R hypothetical protein complement(501746..502285) Escherichia coli O157:H7 str. TW14359 8215045 YP_003076433.1 CDS nrdR NC_013008.1 502436 502885 D transcriptional regulator NrdR 502436..502885 Escherichia coli O157:H7 str. TW14359 8215046 YP_003076434.1 CDS ribD NC_013008.1 502889 503992 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 502889..503992 Escherichia coli O157:H7 str. TW14359 8215047 YP_003076435.1 CDS ribH NC_013008.1 504081 504551 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 504081..504551 Escherichia coli O157:H7 str. TW14359 8215048 YP_003076436.1 CDS nusB NC_013008.1 504571 504990 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 504571..504990 Escherichia coli O157:H7 str. TW14359 8215049 YP_003076437.1 CDS thiL NC_013008.1 505068 506045 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 505068..506045 Escherichia coli O157:H7 str. TW14359 8215050 YP_003076438.1 CDS pgpA NC_013008.1 506023 506538 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 506023..506538 Escherichia coli O157:H7 str. TW14359 8215051 YP_003076439.1 CDS espY3 NC_013008.1 506716 508287 R non-LEE-encoded type III effector complement(506716..508287) Escherichia coli O157:H7 str. TW14359 8215052 YP_003076440.1 CDS yajO NC_013008.1 508518 509492 R oxidoreductase complement(508518..509492) Escherichia coli O157:H7 str. TW14359 8215053 YP_003076441.1 CDS dxs NC_013008.1 509547 511409 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(509547..511409) Escherichia coli O157:H7 str. TW14359 8215054 YP_003076442.1 CDS ispA NC_013008.1 511434 512333 R geranyltranstransferase complement(511434..512333) Escherichia coli O157:H7 str. TW14359 8215055 YP_003076443.1 CDS xseB NC_013008.1 512333 512575 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(512333..512575) Escherichia coli O157:H7 str. TW14359 8215056 YP_003076444.1 CDS thiI NC_013008.1 512781 514229 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 512781..514229 Escherichia coli O157:H7 str. TW14359 8215057 YP_003076445.1 CDS yajL NC_013008.1 514283 514873 R DJ-1 family protein complement(514283..514873) Escherichia coli O157:H7 str. TW14359 8215058 YP_003076446.1 CDS panE NC_013008.1 514836 515747 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(514836..515747) Escherichia coli O157:H7 str. TW14359 8215059 YP_003076447.1 CDS yajQ NC_013008.1 515915 516406 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 515915..516406 Escherichia coli O157:H7 str. TW14359 8215060 YP_003076448.1 CDS yajR NC_013008.1 516534 517898 R transporter complement(516534..517898) Escherichia coli O157:H7 str. TW14359 8215061 YP_003076449.1 CDS cyoE NC_013008.1 518047 518937 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(518047..518937) Escherichia coli O157:H7 str. TW14359 8215062 YP_003076450.1 CDS cyoD NC_013008.1 518949 519278 R cytochrome o ubiquinol oxidase subunit IV complement(518949..519278) Escherichia coli O157:H7 str. TW14359 8215063 YP_003076451.1 CDS cyoC NC_013008.1 519278 519892 R cytochrome o ubiquinol oxidase subunit III complement(519278..519892) Escherichia coli O157:H7 str. TW14359 8215064 YP_003076452.1 CDS cyoB NC_013008.1 519882 521873 R cytochrome o ubiquinol oxidase subunit I complement(519882..521873) Escherichia coli O157:H7 str. TW14359 8215065 YP_003076453.1 CDS cyoA NC_013008.1 521895 522842 R cytochrome o ubiquinol oxidase subunit II complement(521895..522842) Escherichia coli O157:H7 str. TW14359 8215066 YP_003076454.1 CDS ampG NC_013008.1 523302 524777 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(523302..524777) Escherichia coli O157:H7 str. TW14359 8215067 YP_003076455.1 CDS yajG NC_013008.1 524821 525399 R hypothetical protein complement(524821..525399) Escherichia coli O157:H7 str. TW14359 8215068 YP_003076456.1 CDS bolA NC_013008.1 525704 526021 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 525704..526021 Escherichia coli O157:H7 str. TW14359 8215069 YP_003076457.1 CDS tig NC_013008.1 526365 527663 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 526365..527663 Escherichia coli O157:H7 str. TW14359 8215070 YP_003076458.1 CDS clpP NC_013008.1 527908 528531 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 527908..528531 Escherichia coli O157:H7 str. TW14359 8215071 YP_003076459.1 CDS clpX NC_013008.1 528657 529931 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 528657..529931 Escherichia coli O157:H7 str. TW14359 8215072 YP_003076460.1 CDS lon NC_013008.1 530119 532473 D DNA-binding ATP-dependent protease La 530119..532473 Escherichia coli O157:H7 str. TW14359 8215073 YP_003076461.1 CDS hupB NC_013008.1 532682 532954 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 532682..532954 Escherichia coli O157:H7 str. TW14359 8215074 YP_003076462.1 CDS ppiD NC_013008.1 533146 535017 D peptidyl-prolyl cis-trans isomerase D 533146..535017 Escherichia coli O157:H7 str. TW14359 8215075 YP_003076463.1 CDS ybaV NC_013008.1 535168 535539 D hypothetical protein 535168..535539 Escherichia coli O157:H7 str. TW14359 8215076 YP_003076464.1 CDS ybaW NC_013008.1 535645 536043 D hypothetical protein 535645..536043 Escherichia coli O157:H7 str. TW14359 8215077 YP_003076465.1 CDS queC NC_013008.1 536095 536790 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(536095..536790) Escherichia coli O157:H7 str. TW14359 8215078 YP_003076466.1 CDS ybaE NC_013008.1 536855 538555 R ABC transporter periplasmic-binding protein complement(536855..538555) Escherichia coli O157:H7 str. TW14359 8215079 YP_003076467.1 CDS cof NC_013008.1 538655 539473 D thiamin pyrimidine pyrophosphate hydrolase 538655..539473 Escherichia coli O157:H7 str. TW14359 8215080 YP_003076468.1 CDS ybaO NC_013008.1 539625 540083 D DNA-binding transcriptional regulator 539625..540083 Escherichia coli O157:H7 str. TW14359 8215081 YP_003076469.1 CDS mdlA NC_013008.1 540113 541885 D multidrug transporter membrane\ATP-binding proteins 540113..541885 Escherichia coli O157:H7 str. TW14359 8215082 YP_003076470.1 CDS mdlB NC_013008.1 541878 543659 D multidrug transporter membrane\ATP-binding proteins 541878..543659 Escherichia coli O157:H7 str. TW14359 8215083 YP_003076471.1 CDS glnK NC_013008.1 543840 544178 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 543840..544178 Escherichia coli O157:H7 str. TW14359 8215084 YP_003076472.1 CDS amtB NC_013008.1 544208 545494 D ammonium transporter 544208..545494 Escherichia coli O157:H7 str. TW14359 8215085 YP_003076473.1 CDS tesB NC_013008.1 545543 546403 R acyl-CoA thioesterase complement(545543..546403) Escherichia coli O157:H7 str. TW14359 8215086 YP_003076474.1 CDS ybaY NC_013008.1 546621 547193 D outer membrane lipoprotein 546621..547193 Escherichia coli O157:H7 str. TW14359 8215087 YP_003076475.1 CDS ybaZ NC_013008.1 547226 547615 R methyltransferase complement(547226..547615) Escherichia coli O157:H7 str. TW14359 8215088 YP_003076476.1 CDS ybaA NC_013008.1 547916 548269 D hypothetical protein 547916..548269 Escherichia coli O157:H7 str. TW14359 8215089 YP_003076477.1 CDS ylaB NC_013008.1 548311 549861 R hypothetical protein complement(548311..549861) Escherichia coli O157:H7 str. TW14359 8215090 YP_003076478.1 CDS ylaC NC_013008.1 550025 550495 R inner membrane protein complement(550025..550495) Escherichia coli O157:H7 str. TW14359 8215091 YP_003076479.1 CDS maa NC_013008.1 550611 551162 R maltose O-acetyltransferase complement(550611..551162) Escherichia coli O157:H7 str. TW14359 8215092 YP_003076480.1 CDS hha NC_013008.1 551334 551552 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(551334..551552) Escherichia coli O157:H7 str. TW14359 8215093 YP_003076481.1 CDS ybaJ NC_013008.1 551578 551952 R hypothetical protein complement(551578..551952) Escherichia coli O157:H7 str. TW14359 8215094 YP_003076482.1 CDS acrB NC_013008.1 552498 555647 R multidrug efflux system protein complement(552498..555647) Escherichia coli O157:H7 str. TW14359 8215095 YP_003076483.1 CDS acrA NC_013008.1 555670 556863 R multidrug efflux system complement(555670..556863) Escherichia coli O157:H7 str. TW14359 8215096 YP_003076484.1 CDS acrR NC_013008.1 557005 557652 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 557005..557652 Escherichia coli O157:H7 str. TW14359 8215097 YP_003076485.1 CDS kefA NC_013008.1 557780 561142 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 557780..561142 Escherichia coli O157:H7 str. TW14359 8215098 YP_003076486.1 CDS ybaM NC_013008.1 561181 561345 R hypothetical protein complement(561181..561345) Escherichia coli O157:H7 str. TW14359 8215099 YP_003076487.1 CDS priC NC_013008.1 561359 561886 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(561359..561886) Escherichia coli O157:H7 str. TW14359 8215100 YP_003076488.1 CDS ybaN NC_013008.1 561956 562333 D hypothetical protein 561956..562333 Escherichia coli O157:H7 str. TW14359 8215101 YP_003076489.1 CDS apt NC_013008.1 562486 563037 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 562486..563037 Escherichia coli O157:H7 str. TW14359 8215102 YP_003076490.1 CDS dnaX NC_013008.1 563166 565097 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 563166..565097 Escherichia coli O157:H7 str. TW14359 8215103 YP_003076491.1 CDS ybaB NC_013008.1 565150 565479 D hypothetical protein 565150..565479 Escherichia coli O157:H7 str. TW14359 8215104 YP_003076492.1 CDS recR NC_013008.1 565479 566084 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 565479..566084 Escherichia coli O157:H7 str. TW14359 8215105 YP_003076493.1 CDS htpG NC_013008.1 566194 568068 D molecular chaperone; heat shock protein 90 566194..568068 Escherichia coli O157:H7 str. TW14359 8215106 YP_003076494.1 CDS adk NC_013008.1 568249 568893 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 568249..568893 Escherichia coli O157:H7 str. TW14359 8215107 YP_003076495.1 CDS hemH NC_013008.1 569025 569987 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 569025..569987 Escherichia coli O157:H7 str. TW14359 8215108 YP_003076496.1 CDS aes NC_013008.1 569984 570943 R acetyl esterase complement(569984..570943) Escherichia coli O157:H7 str. TW14359 8215109 YP_003076497.1 CDS gsk NC_013008.1 571095 572399 D inosine/guanosine kinase 571095..572399 Escherichia coli O157:H7 str. TW14359 8215110 YP_003076498.1 CDS ybaL NC_013008.1 572532 574208 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(572532..574208) Escherichia coli O157:H7 str. TW14359 8215111 YP_003076499.1 CDS fsr NC_013008.1 574445 575665 R fosmidomycin efflux system complement(574445..575665) Escherichia coli O157:H7 str. TW14359 8215112 YP_003076500.1 CDS ushA NC_013008.1 575883 577535 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 575883..577535 Escherichia coli O157:H7 str. TW14359 8215113 YP_003076501.1 CDS ybaK NC_013008.1 577572 578051 R hypothetical protein complement(577572..578051) Escherichia coli O157:H7 str. TW14359 8215114 YP_003076502.1 CDS ybaP NC_013008.1 578255 579049 R hypothetical protein complement(578255..579049) Escherichia coli O157:H7 str. TW14359 8215115 YP_003076503.1 CDS ybaQ NC_013008.1 579187 579528 D DNA-binding transcriptional regulator 579187..579528 Escherichia coli O157:H7 str. TW14359 8215116 YP_003076504.1 CDS copA NC_013008.1 579743 582247 R copper exporting ATPase complement(579743..582247) Escherichia coli O157:H7 str. TW14359 8215117 YP_003076505.1 CDS ybaS NC_013008.1 582509 583441 D catalyzes the formation of glutamate from glutamine; glutaminase 582509..583441 Escherichia coli O157:H7 str. TW14359 8215118 YP_003076506.1 CDS ybaT NC_013008.1 583444 584736 D transporter 583444..584736 Escherichia coli O157:H7 str. TW14359 8215119 YP_003076507.1 CDS ECSP_0554 NC_013008.1 585074 586429 D outer membrane export protein 585074..586429 Escherichia coli O157:H7 str. TW14359 8215120 YP_003076508.1 CDS ECSP_0555 NC_013008.1 586532 590917 D hypothetical protein 586532..590917 Escherichia coli O157:H7 str. TW14359 8215121 YP_003076509.1 CDS ECSP_0556 NC_013008.1 591125 604264 D RTX family exoprotein 591125..604264 Escherichia coli O157:H7 str. TW14359 8215122 YP_003076510.1 CDS ECSP_0558 NC_013008.1 606685 608847 D cytoplasmic membrane export protein 606685..608847 Escherichia coli O157:H7 str. TW14359 8215124 YP_003076511.1 CDS ECSP_0559 NC_013008.1 608844 610019 D membrane spanning export protein 608844..610019 Escherichia coli O157:H7 str. TW14359 8215125 YP_003076512.1 CDS cueR NC_013008.1 610016 610423 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 610016..610423 Escherichia coli O157:H7 str. TW14359 8215126 YP_003076513.1 CDS ECSP_0561 NC_013008.1 610627 611049 R hypothetical protein complement(610627..611049) Escherichia coli O157:H7 str. TW14359 8215127 YP_003076514.1 CDS ECSP_0562 NC_013008.1 611134 612150 R hypothetical protein complement(611134..612150) Escherichia coli O157:H7 str. TW14359 8215128 YP_003076515.1 CDS ECSP_0563 NC_013008.1 612248 612370 R hypothetical protein complement(612248..612370) Escherichia coli O157:H7 str. TW14359 8215129 YP_003076516.1 CDS ECSP_0564 NC_013008.1 612517 612879 D hypothetical protein 612517..612879 Escherichia coli O157:H7 str. TW14359 8215130 YP_003076517.1 CDS ybbJ NC_013008.1 613058 613516 R hypothetical protein complement(613058..613516) Escherichia coli O157:H7 str. TW14359 8215131 YP_003076518.1 CDS ybbK NC_013008.1 613513 614430 R protease, membrane anchored complement(613513..614430) Escherichia coli O157:H7 str. TW14359 8215132 YP_003076519.1 CDS ybbL NC_013008.1 614576 615253 D ABC transporter ATP-binding protein YbbL 614576..615253 Escherichia coli O157:H7 str. TW14359 8215133 YP_003076520.1 CDS ybbM NC_013008.1 615240 616019 D inner membrane protein 615240..616019 Escherichia coli O157:H7 str. TW14359 8215134 YP_003076521.1 CDS ybbN NC_013008.1 616082 616936 R thioredoxin domain-containing protein complement(616082..616936) Escherichia coli O157:H7 str. TW14359 8215135 YP_003076522.1 CDS ybbO NC_013008.1 616997 617806 R short chain dehydrogenase complement(616997..617806) Escherichia coli O157:H7 str. TW14359 8215136 YP_003076523.1 CDS tesA NC_013008.1 617796 618422 R multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(617796..618422) Escherichia coli O157:H7 str. TW14359 8215137 YP_003076524.1 CDS ybbA NC_013008.1 618390 619076 D ABC transporter ATP-binding protein YbbA 618390..619076 Escherichia coli O157:H7 str. TW14359 8215138 YP_003076525.1 CDS ybbP NC_013008.1 619073 621487 D inner membrane protein 619073..621487 Escherichia coli O157:H7 str. TW14359 8215139 YP_003076526.1 CDS ECSP_0574 NC_013008.1 621917 626113 D hypothetical protein 621917..626113 Escherichia coli O157:H7 str. TW14359 8215140 YP_003076527.1 CDS ybbD NC_013008.1 626094 626354 D hypothetical protein 626094..626354 Escherichia coli O157:H7 str. TW14359 8215141 YP_003076528.1 CDS ECSP_0576 NC_013008.1 626537 626689 R hypothetical protein complement(626537..626689) Escherichia coli O157:H7 str. TW14359 8215142 YP_003076529.1 CDS ylbG NC_013008.1 627098 627505 R DNA-binding transcriptional regulator complement(627098..627505) Escherichia coli O157:H7 str. TW14359 8215143 YP_003076530.1 CDS ybbB NC_013008.1 627585 628679 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(627585..628679) Escherichia coli O157:H7 str. TW14359 8215144 YP_003076531.1 CDS ybbS NC_013008.1 628748 629674 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(628748..629674) Escherichia coli O157:H7 str. TW14359 8215145 YP_003076532.1 CDS allA NC_013008.1 629904 630386 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 629904..630386 Escherichia coli O157:H7 str. TW14359 8215146 YP_003076533.1 CDS allR NC_013008.1 630464 631279 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 630464..631279 Escherichia coli O157:H7 str. TW14359 8215147 YP_003076534.1 CDS gcl NC_013008.1 631369 633150 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 631369..633150 Escherichia coli O157:H7 str. TW14359 8215148 YP_003076535.1 CDS hyi NC_013008.1 633163 633939 D hydroxypyruvate isomerase 633163..633939 Escherichia coli O157:H7 str. TW14359 8215149 YP_003076536.1 CDS glxR NC_013008.1 634040 634918 D tartronate semialdehyde reductase, NADH-dependent 634040..634918 Escherichia coli O157:H7 str. TW14359 8215150 YP_003076537.1 CDS ybbW NC_013008.1 635087 636478 D allantoin permease 635087..636478 Escherichia coli O157:H7 str. TW14359 8215151 YP_003076538.1 CDS ybbY NC_013008.1 637933 639234 D purine permease YbbY 637933..639234 Escherichia coli O157:H7 str. TW14359 8215153 YP_003076539.1 CDS glxK NC_013008.1 639256 640401 D glycerate kinase II 639256..640401 Escherichia coli O157:H7 str. TW14359 8215154 YP_003076540.1 CDS ylbA NC_013008.1 640629 641414 R hypothetical protein complement(640629..641414) Escherichia coli O157:H7 str. TW14359 8215155 YP_003076541.1 CDS allC NC_013008.1 641425 642660 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(641425..642660) Escherichia coli O157:H7 str. TW14359 8215156 YP_003076542.1 CDS allD NC_013008.1 642682 643731 R ureidoglycolate dehydrogenase complement(642682..643731) Escherichia coli O157:H7 str. TW14359 8215157 YP_003076543.1 CDS fdrA NC_013008.1 644048 645715 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 644048..645715 Escherichia coli O157:H7 str. TW14359 8215158 YP_003076544.1 CDS ylbE NC_013008.1 645725 646984 D hypothetical protein 645725..646984 Escherichia coli O157:H7 str. TW14359 8215159 YP_003076545.1 CDS ylbF NC_013008.1 646995 647810 D hypothetical protein 646995..647810 Escherichia coli O157:H7 str. TW14359 8215160 YP_003076546.1 CDS ybcF NC_013008.1 647807 648700 D carbamate kinase 647807..648700 Escherichia coli O157:H7 str. TW14359 8215161 YP_003076547.1 CDS purK NC_013008.1 648839 649906 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(648839..649906) Escherichia coli O157:H7 str. TW14359 8215162 YP_003076548.1 CDS purE NC_013008.1 649903 650412 R N5-carboxyaminoimidazole ribonucleotide mutase complement(649903..650412) Escherichia coli O157:H7 str. TW14359 8215163 YP_003076549.1 CDS lpxH NC_013008.1 650530 651252 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(650530..651252) Escherichia coli O157:H7 str. TW14359 8215164 YP_003076550.1 CDS ppiB NC_013008.1 651255 651749 R peptidyl-prolyl cis-trans isomerase B complement(651255..651749) Escherichia coli O157:H7 str. TW14359 8215165 YP_003076551.1 CDS cysS NC_013008.1 651923 653308 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 651923..653308 Escherichia coli O157:H7 str. TW14359 8215166 YP_003076552.1 CDS ybcI NC_013008.1 653344 653865 R hypothetical protein complement(653344..653865) Escherichia coli O157:H7 str. TW14359 8215167 YP_003076553.1 CDS ybcJ NC_013008.1 653973 654185 R hypothetical protein complement(653973..654185) Escherichia coli O157:H7 str. TW14359 8215168 YP_003076554.1 CDS folD NC_013008.1 654187 655053 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(654187..655053) Escherichia coli O157:H7 str. TW14359 8215169 YP_003076555.1 CDS sfmA NC_013008.1 655533 656075 D fimbrial-like adhesin protein 655533..656075 Escherichia coli O157:H7 str. TW14359 8215170 YP_003076556.1 CDS sfmC NC_013008.1 656295 656987 D pilin chaperone, periplasmic 656295..656987 Escherichia coli O157:H7 str. TW14359 8215171 YP_003076557.1 CDS sfmD NC_013008.1 657018 659627 D outer membrane export usher protein 657018..659627 Escherichia coli O157:H7 str. TW14359 8215172 YP_003076558.1 CDS sfmH NC_013008.1 659640 660647 D fimbrial-like adhesin protein 659640..660647 Escherichia coli O157:H7 str. TW14359 8215173 YP_003076559.1 CDS sfmF NC_013008.1 660658 661173 D fimbrial protein 660658..661173 Escherichia coli O157:H7 str. TW14359 8215174 YP_003076560.1 CDS fimZ NC_013008.1 661176 661808 R activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ complement(661176..661808) Escherichia coli O157:H7 str. TW14359 8215175 YP_003076561.1 CDS envY NC_013008.1 662173 662934 R DNA-binding transcriptional activator of porin biosynthesis complement(662173..662934) Escherichia coli O157:H7 str. TW14359 8215177 YP_003076562.1 CDS ybcH NC_013008.1 663117 664007 R hypothetical protein complement(663117..664007) Escherichia coli O157:H7 str. TW14359 8215178 YP_003076563.1 CDS nfrA NC_013008.1 664008 666980 R bacteriophage N4 receptor, outer membrane subunit complement(664008..666980) Escherichia coli O157:H7 str. TW14359 8215179 YP_003076564.1 CDS nfrB NC_013008.1 666967 669204 R bacteriophage N4 adsorption protein B complement(666967..669204) Escherichia coli O157:H7 str. TW14359 8215180 YP_003076565.1 CDS ECSP_0615 NC_013008.1 669470 670606 R transposase complement(669470..670606) Escherichia coli O157:H7 str. TW14359 8215181 YP_003076566.1 CDS ECSP_0616 NC_013008.1 670821 671042 R hypothetical protein complement(670821..671042) Escherichia coli O157:H7 str. TW14359 8215182 YP_003076567.1 CDS ECSP_0617 NC_013008.1 671069 672403 R hypothetical protein complement(671069..672403) Escherichia coli O157:H7 str. TW14359 8215183 YP_003076568.1 CDS ECSP_0618 NC_013008.1 672572 672832 R hypothetical protein complement(672572..672832) Escherichia coli O157:H7 str. TW14359 8215184 YP_003076569.1 CDS ECSP_0619 NC_013008.1 672996 677846 R hypothetical protein complement(672996..677846) Escherichia coli O157:H7 str. TW14359 8215185 YP_003076570.1 CDS ECSP_0620 NC_013008.1 677866 678327 R hypothetical protein complement(677866..678327) Escherichia coli O157:H7 str. TW14359 8215186 YP_003076571.1 CDS ECSP_0621 NC_013008.1 678355 680256 R hypothetical protein complement(678355..680256) Escherichia coli O157:H7 str. TW14359 8215187 YP_003076572.1 CDS cusS NC_013008.1 680850 682298 R sensor kinase CusS complement(680850..682298) Escherichia coli O157:H7 str. TW14359 8215188 YP_003076573.1 CDS cusR NC_013008.1 682288 682971 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(682288..682971) Escherichia coli O157:H7 str. TW14359 8215189 YP_003076574.1 CDS cusC NC_013008.1 683128 684510 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 683128..684510 Escherichia coli O157:H7 str. TW14359 8215190 YP_003076575.1 CDS cusF NC_013008.1 684534 684866 D periplasmic copper-binding protein 684534..684866 Escherichia coli O157:H7 str. TW14359 8215191 YP_003076576.1 CDS cusB NC_013008.1 684882 686105 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 684882..686105 Escherichia coli O157:H7 str. TW14359 8215192 YP_003076577.1 CDS cusA NC_013008.1 686117 689254 D copper/silver efflux system, membrane component 686117..689254 Escherichia coli O157:H7 str. TW14359 8215193 YP_003076578.1 CDS pheP NC_013008.1 689356 690732 D phenylalanine transporter 689356..690732 Escherichia coli O157:H7 str. TW14359 8215194 YP_003076579.1 CDS ybdG NC_013008.1 690800 692047 R mechanosensitive channel complement(690800..692047) Escherichia coli O157:H7 str. TW14359 8215195 YP_003076580.1 CDS nfnB NC_013008.1 692155 692808 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(692155..692808) Escherichia coli O157:H7 str. TW14359 8215196 YP_003076581.1 CDS ybdF NC_013008.1 692902 693270 R hypothetical protein complement(692902..693270) Escherichia coli O157:H7 str. TW14359 8215197 YP_003076582.1 CDS ybdJ NC_013008.1 693335 693583 R inner membrane protein complement(693335..693583) Escherichia coli O157:H7 str. TW14359 8215198 YP_003076583.1 CDS ybdK NC_013008.1 693649 694767 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(693649..694767) Escherichia coli O157:H7 str. TW14359 8215199 YP_003076584.1 CDS ECSP_0634 NC_013008.1 695062 695358 D hypothetical protein 695062..695358 Escherichia coli O157:H7 str. TW14359 8215200 YP_003076585.1 CDS hokE NC_013008.1 695709 695861 D toxic polypeptide, small 695709..695861 Escherichia coli O157:H7 str. TW14359 8215201 YP_003076586.1 CDS entD NC_013008.1 695983 696612 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(695983..696612) Escherichia coli O157:H7 str. TW14359 8215202 YP_003076587.1 CDS fepA NC_013008.1 696778 699018 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(696778..699018) Escherichia coli O157:H7 str. TW14359 8215203 YP_003076588.1 CDS fes NC_013008.1 699339 700463 D enterobactin/ferric enterobactin esterase 699339..700463 Escherichia coli O157:H7 str. TW14359 8215204 YP_003076589.1 CDS ybdZ NC_013008.1 700466 700684 D hypothetical protein 700466..700684 Escherichia coli O157:H7 str. TW14359 8215205 YP_003076590.1 CDS entF NC_013008.1 700681 704562 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 700681..704562 Escherichia coli O157:H7 str. TW14359 8215206 YP_003076591.1 CDS fepE NC_013008.1 704778 705911 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 704778..705911 Escherichia coli O157:H7 str. TW14359 8215207 YP_003076592.1 CDS fepC NC_013008.1 705908 706723 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(705908..706723) Escherichia coli O157:H7 str. TW14359 8215208 YP_003076593.1 CDS fepG NC_013008.1 706720 707712 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(706720..707712) Escherichia coli O157:H7 str. TW14359 8215209 YP_003076594.1 CDS fepD NC_013008.1 707709 708713 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(707709..708713) Escherichia coli O157:H7 str. TW14359 8215210 YP_003076595.1 CDS ybdA NC_013008.1 708824 710074 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 708824..710074 Escherichia coli O157:H7 str. TW14359 8215211 YP_003076596.1 CDS fepB NC_013008.1 710078 711034 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(710078..711034) Escherichia coli O157:H7 str. TW14359 8215212 YP_003076597.1 CDS entC NC_013008.1 711223 712398 D isochorismate synthase 1 711223..712398 Escherichia coli O157:H7 str. TW14359 8215213 YP_003076598.1 CDS entE NC_013008.1 712408 714018 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 712408..714018 Escherichia coli O157:H7 str. TW14359 8215214 YP_003076599.1 CDS entB NC_013008.1 714032 714889 D 2,3-dihydro-2,3-dihydroxybenzoate synthetase 714032..714889 Escherichia coli O157:H7 str. TW14359 8215215 YP_003076600.1 CDS entA NC_013008.1 714889 715635 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 714889..715635 Escherichia coli O157:H7 str. TW14359 8215216 YP_003076601.1 CDS ybdB NC_013008.1 715638 716051 D hypothetical protein 715638..716051 Escherichia coli O157:H7 str. TW14359 8215217 YP_003076602.1 CDS cstA NC_013008.1 716232 718337 D carbon starvation protein 716232..718337 Escherichia coli O157:H7 str. TW14359 8215218 YP_003076603.1 CDS ybdD NC_013008.1 718519 718716 D hypothetical protein 718519..718716 Escherichia coli O157:H7 str. TW14359 8215219 YP_003076604.1 CDS ybdH NC_013008.1 718726 719814 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(718726..719814) Escherichia coli O157:H7 str. TW14359 8215220 YP_003076605.1 CDS ybdL NC_013008.1 719923 721083 D catalyzes the transfer of an amino moiety; aminotransferase 719923..721083 Escherichia coli O157:H7 str. TW14359 8215221 YP_003076606.1 CDS ybdM NC_013008.1 721084 721713 R hypothetical protein complement(721084..721713) Escherichia coli O157:H7 str. TW14359 8215222 YP_003076607.1 CDS ybdN NC_013008.1 721686 722906 R hypothetical protein complement(721686..722906) Escherichia coli O157:H7 str. TW14359 8215223 YP_003076608.1 CDS ybdO NC_013008.1 723053 723955 R DNA-binding transcriptional regulator complement(723053..723955) Escherichia coli O157:H7 str. TW14359 8215224 YP_003076609.1 CDS dsbG NC_013008.1 724165 724911 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(724165..724911) Escherichia coli O157:H7 str. TW14359 8215225 YP_003076610.1 CDS ahpC NC_013008.1 725283 725846 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 725283..725846 Escherichia coli O157:H7 str. TW14359 8215226 YP_003076611.1 CDS ahpF NC_013008.1 725975 727540 D alkyl hydroperoxide reductase 725975..727540 Escherichia coli O157:H7 str. TW14359 8215227 YP_003076612.1 CDS uspG NC_013008.1 727661 728089 R universal stress protein UP12 complement(727661..728089) Escherichia coli O157:H7 str. TW14359 8215228 YP_003076613.1 CDS ybdR NC_013008.1 728310 729548 D oxidoreductase 728310..729548 Escherichia coli O157:H7 str. TW14359 8215229 YP_003076614.1 CDS rnk NC_013008.1 729779 730189 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(729779..730189) Escherichia coli O157:H7 str. TW14359 8215230 YP_003076615.1 CDS rna NC_013008.1 730419 731225 R ribonuclease I complement(730419..731225) Escherichia coli O157:H7 str. TW14359 8215231 YP_003076616.1 CDS citT NC_013008.1 731339 732802 R citrate:succinate antiporter complement(731339..732802) Escherichia coli O157:H7 str. TW14359 8215232 YP_003076617.1 CDS citG NC_013008.1 732853 733731 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(732853..733731) Escherichia coli O157:H7 str. TW14359 8215233 YP_003076618.1 CDS citX NC_013008.1 733706 734257 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase complement(733706..734257) Escherichia coli O157:H7 str. TW14359 8215234 YP_003076619.1 CDS citF NC_013008.1 734261 735793 R citrate lyase, citrate-ACP transferase subunit alpha complement(734261..735793) Escherichia coli O157:H7 str. TW14359 8215235 YP_003076620.1 CDS citE NC_013008.1 735804 736712 R citrate lyase, citryl-ACP lyase subunit beta complement(735804..736712) Escherichia coli O157:H7 str. TW14359 8215236 YP_003076621.1 CDS citD NC_013008.1 736709 737005 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(736709..737005) Escherichia coli O157:H7 str. TW14359 8215237 YP_003076622.1 CDS citC NC_013008.1 737020 738078 R citrate lyase synthetase complement(737020..738078) Escherichia coli O157:H7 str. TW14359 8215238 YP_003076623.1 CDS citA NC_013008.1 738458 740116 D sensory histidine kinase in two-component regulatory system with citB 738458..740116 Escherichia coli O157:H7 str. TW14359 8215239 YP_003076624.1 CDS dpiA NC_013008.1 740085 740765 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 740085..740765 Escherichia coli O157:H7 str. TW14359 8215240 YP_003076625.1 CDS dcuC NC_013008.1 740806 742191 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(740806..742191) Escherichia coli O157:H7 str. TW14359 8215241 YP_003076626.1 CDS pagP NC_013008.1 742780 743340 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 742780..743340 Escherichia coli O157:H7 str. TW14359 8215242 YP_003076627.1 CDS cspE NC_013008.1 743515 743724 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 743515..743724 Escherichia coli O157:H7 str. TW14359 8215243 YP_003076628.1 CDS crcB NC_013008.1 743778 744161 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(743778..744161) Escherichia coli O157:H7 str. TW14359 8215244 YP_003076629.1 CDS ybeM NC_013008.1 744254 745042 D carbon-nitrogen hydrolase 744254..745042 Escherichia coli O157:H7 str. TW14359 8215245 YP_003076630.1 CDS tatE NC_013008.1 745171 745374 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 745171..745374 Escherichia coli O157:H7 str. TW14359 8215246 YP_003076631.1 CDS lipA NC_013008.1 745475 746440 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(745475..746440) Escherichia coli O157:H7 str. TW14359 8215247 YP_003076632.1 CDS ybeF NC_013008.1 746649 747602 R DNA-binding transcriptional regulator complement(746649..747602) Escherichia coli O157:H7 str. TW14359 8215248 YP_003076633.1 CDS lipB NC_013008.1 747862 748503 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(747862..748503) Escherichia coli O157:H7 str. TW14359 8215249 YP_003076634.1 CDS ybeD NC_013008.1 748604 748867 R hypothetical protein complement(748604..748867) Escherichia coli O157:H7 str. TW14359 8215250 YP_003076635.1 CDS dacA NC_013008.1 748977 750188 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A complement(748977..750188) Escherichia coli O157:H7 str. TW14359 8215251 YP_003076636.1 CDS rlpA NC_013008.1 750328 751416 R rare lipoprotein A complement(750328..751416) Escherichia coli O157:H7 str. TW14359 8215252 YP_003076637.1 CDS mrdB NC_013008.1 751427 752539 R cell wall shape-determining protein complement(751427..752539) Escherichia coli O157:H7 str. TW14359 8215253 YP_003076638.1 CDS mrdA NC_013008.1 752542 754443 R penicillin-binding protein 2 complement(752542..754443) Escherichia coli O157:H7 str. TW14359 8215254 YP_003076639.1 CDS ybeA NC_013008.1 754474 754941 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(754474..754941) Escherichia coli O157:H7 str. TW14359 8215255 YP_003076640.1 CDS ybeB NC_013008.1 754945 755262 R hypothetical protein complement(754945..755262) Escherichia coli O157:H7 str. TW14359 8215256 YP_003076641.1 CDS cobC NC_013008.1 755522 756133 R alpha-ribazole-5'-P phosphatase complement(755522..756133) Escherichia coli O157:H7 str. TW14359 8215257 YP_003076642.1 CDS nadD NC_013008.1 756157 756798 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(756157..756798) Escherichia coli O157:H7 str. TW14359 8215258 YP_003076643.1 CDS holA NC_013008.1 756800 757831 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(756800..757831) Escherichia coli O157:H7 str. TW14359 8215259 YP_003076644.1 CDS rlpB NC_013008.1 757831 758412 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(757831..758412) Escherichia coli O157:H7 str. TW14359 8215260 YP_003076645.1 CDS leuS NC_013008.1 758427 761009 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(758427..761009) Escherichia coli O157:H7 str. TW14359 8215261 YP_003076646.1 CDS ybeL NC_013008.1 761245 761727 D hypothetical protein 761245..761727 Escherichia coli O157:H7 str. TW14359 8215262 YP_003076647.1 CDS ybeR NC_013008.1 762939 763646 D hypothetical protein 762939..763646 Escherichia coli O157:H7 str. TW14359 8215264 YP_003076648.1 CDS djlB NC_013008.1 763643 765070 D chaperone 763643..765070 Escherichia coli O157:H7 str. TW14359 8215265 YP_003076649.1 CDS ybeT NC_013008.1 765080 765634 R outer membrane protein complement(765080..765634) Escherichia coli O157:H7 str. TW14359 8215266 YP_003076650.1 CDS ybeU NC_013008.1 765736 766443 D tRNA ligase 765736..766443 Escherichia coli O157:H7 str. TW14359 8215267 YP_003076651.1 CDS hscC NC_013008.1 767951 769621 R molecular chaperone DnaK complement(767951..769621) Escherichia coli O157:H7 str. TW14359 8215268 YP_003076652.1 CDS rihA NC_013008.1 769705 770640 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(769705..770640) Escherichia coli O157:H7 str. TW14359 8215269 YP_003076653.1 CDS gltL NC_013008.1 770758 771483 R glutamate and aspartate ABC transporter ATP-binding protein complement(770758..771483) Escherichia coli O157:H7 str. TW14359 8215270 YP_003076654.1 CDS gltK NC_013008.1 771483 772157 R glutamate and aspartate ABC transporter membrane protein complement(771483..772157) Escherichia coli O157:H7 str. TW14359 8215271 YP_003076655.1 CDS gltJ NC_013008.1 772157 772897 R glutamate and aspartate ABC transporter membrane protein complement(772157..772897) Escherichia coli O157:H7 str. TW14359 8215272 YP_003076656.1 CDS gltI NC_013008.1 773067 773975 R glutamate and aspartate transporter subunit complement(773067..773975) Escherichia coli O157:H7 str. TW14359 8215273 YP_003076657.1 CDS lnt NC_013008.1 774372 775910 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(774372..775910) Escherichia coli O157:H7 str. TW14359 8215274 YP_003076658.1 CDS corC NC_013008.1 775935 776813 R ion transport complement(775935..776813) Escherichia coli O157:H7 str. TW14359 8215275 YP_003076659.1 CDS ybeY NC_013008.1 776903 777370 R metalloprotease complement(776903..777370) Escherichia coli O157:H7 str. TW14359 8215276 YP_003076660.1 CDS ybeZ NC_013008.1 777367 778407 R hypothetical protein complement(777367..778407) Escherichia coli O157:H7 str. TW14359 8215277 YP_003076661.1 CDS miaB NC_013008.1 778560 779984 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(778560..779984) Escherichia coli O157:H7 str. TW14359 8215278 YP_003076662.1 CDS ubiF NC_013008.1 780130 781305 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 780130..781305 Escherichia coli O157:H7 str. TW14359 8215279 YP_003076663.1 CDS asnB NC_013008.1 782544 784208 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(782544..784208) Escherichia coli O157:H7 str. TW14359 8215287 YP_003076664.1 CDS nagD NC_013008.1 784465 785217 R UMP phosphatase complement(784465..785217) Escherichia coli O157:H7 str. TW14359 8215288 YP_003076665.1 CDS nagC NC_013008.1 785265 786485 R DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine complement(785265..786485) Escherichia coli O157:H7 str. TW14359 8215289 YP_003076666.1 CDS nagA NC_013008.1 786494 787642 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(786494..787642) Escherichia coli O157:H7 str. TW14359 8215290 YP_003076667.1 CDS nagB NC_013008.1 787702 788502 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(787702..788502) Escherichia coli O157:H7 str. TW14359 8215291 YP_003076668.1 CDS nagE NC_013008.1 788835 790781 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 788835..790781 Escherichia coli O157:H7 str. TW14359 8215292 YP_003076669.1 CDS glnS NC_013008.1 790984 792648 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 790984..792648 Escherichia coli O157:H7 str. TW14359 8215293 YP_003076670.1 CDS ECSP_0728 NC_013008.1 792721 792915 R hypothetical protein complement(792721..792915) Escherichia coli O157:H7 str. TW14359 8215294 YP_003076671.1 CDS ybfN NC_013008.1 794682 795008 D lipoprotein 794682..795008 Escherichia coli O157:H7 str. TW14359 8215296 YP_003076672.1 CDS fur NC_013008.1 795092 795538 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(795092..795538) Escherichia coli O157:H7 str. TW14359 8215297 YP_003076673.1 CDS fldA NC_013008.1 795827 796357 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(795827..796357) Escherichia coli O157:H7 str. TW14359 8215298 YP_003076674.1 CDS ybfE NC_013008.1 796497 796790 R LexA regulated protein complement(796497..796790) Escherichia coli O157:H7 str. TW14359 8215299 YP_003076675.1 CDS ybfF NC_013008.1 796930 797694 R hypothetical protein complement(796930..797694) Escherichia coli O157:H7 str. TW14359 8215300 YP_003076676.1 CDS seqA NC_013008.1 797879 798424 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 797879..798424 Escherichia coli O157:H7 str. TW14359 8215301 YP_003076677.1 CDS pgm NC_013008.1 798450 800090 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 798450..800090 Escherichia coli O157:H7 str. TW14359 8215302 YP_003076678.1 CDS potE NC_013008.1 800147 801466 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(800147..801466) Escherichia coli O157:H7 str. TW14359 8215303 YP_003076679.1 CDS speF NC_013008.1 801463 803670 R ornithine decarboxylase complement(801463..803670) Escherichia coli O157:H7 str. TW14359 8215304 YP_003076680.1 CDS ECSP_0739 NC_013008.1 804055 804189 R hypothetical protein complement(804055..804189) Escherichia coli O157:H7 str. TW14359 8215305 YP_003076681.1 CDS kdpE NC_013008.1 804351 805028 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(804351..805028) Escherichia coli O157:H7 str. TW14359 8215306 YP_003076682.1 CDS kdpD NC_013008.1 805025 807709 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(805025..807709) Escherichia coli O157:H7 str. TW14359 8215307 YP_003076683.1 CDS kdpC NC_013008.1 807702 808274 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(807702..808274) Escherichia coli O157:H7 str. TW14359 8215308 YP_003076684.1 CDS kdpB NC_013008.1 808283 810331 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(808283..810331) Escherichia coli O157:H7 str. TW14359 8215309 YP_003076685.1 CDS kdpA NC_013008.1 810354 812027 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(810354..812027) Escherichia coli O157:H7 str. TW14359 8215310 YP_003076686.1 CDS ybfA NC_013008.1 812429 812635 D hypothetical protein 812429..812635 Escherichia coli O157:H7 str. TW14359 8215311 YP_003076687.1 CDS ybfO NC_013008.1 812875 817074 D hypothetical protein 812875..817074 Escherichia coli O157:H7 str. TW14359 8215312 YP_003076688.1 CDS ybfC NC_013008.1 817098 817640 D hypothetical protein 817098..817640 Escherichia coli O157:H7 str. TW14359 8215313 YP_003076689.1 CDS ECSP_0748 NC_013008.1 819227 820363 D transposase 819227..820363 Escherichia coli O157:H7 str. TW14359 8215314 YP_003076690.1 CDS ybgA NC_013008.1 820512 821021 D hypothetical protein 820512..821021 Escherichia coli O157:H7 str. TW14359 8215315 YP_003076691.1 CDS phr NC_013008.1 821018 822436 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 821018..822436 Escherichia coli O157:H7 str. TW14359 8215316 YP_003076692.1 CDS ybgH NC_013008.1 822586 824067 R transporter complement(822586..824067) Escherichia coli O157:H7 str. TW14359 8215317 YP_003076693.1 CDS ybgI NC_013008.1 824338 825081 D hydrolase-oxidase 824338..825081 Escherichia coli O157:H7 str. TW14359 8215318 YP_003076694.1 CDS ybgJ NC_013008.1 825104 825760 D hypothetical protein 825104..825760 Escherichia coli O157:H7 str. TW14359 8215319 YP_003076695.1 CDS ybgK NC_013008.1 825754 826686 D hypothetical protein 825754..826686 Escherichia coli O157:H7 str. TW14359 8215320 YP_003076696.1 CDS ybgL NC_013008.1 826676 827410 D LamB/YcsF family protein 826676..827410 Escherichia coli O157:H7 str. TW14359 8215321 YP_003076697.1 CDS nei NC_013008.1 827446 828267 D endonuclease VIII, 5-formyluracil 827446..828267 Escherichia coli O157:H7 str. TW14359 8215322 YP_003076698.1 CDS abrB NC_013008.1 828233 829279 R regulator complement(828233..829279) Escherichia coli O157:H7 str. TW14359 8215323 YP_003076699.1 CDS ybgO NC_013008.1 829428 830489 R fimbrial-like adhesin protein complement(829428..830489) Escherichia coli O157:H7 str. TW14359 8215324 YP_003076700.1 CDS ybgP NC_013008.1 830486 831217 R pili assembly protein complement(830486..831217) Escherichia coli O157:H7 str. TW14359 8215325 YP_003076701.1 CDS ECSP_0760 NC_013008.1 831232 833682 R outer membrane usher protein complement(831232..833682) Escherichia coli O157:H7 str. TW14359 8215326 YP_003076702.1 CDS ybgD NC_013008.1 833741 834307 R fimbrial-like adhesin protein complement(833741..834307) Escherichia coli O157:H7 str. TW14359 8215327 YP_003076703.1 CDS gltA NC_013008.1 834694 835977 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(834694..835977) Escherichia coli O157:H7 str. TW14359 8215328 YP_003076704.1 CDS sdhC NC_013008.1 836686 837075 D succinate dehydrogenase cytochrome b556 large membrane subunit 836686..837075 Escherichia coli O157:H7 str. TW14359 8215329 YP_003076705.1 CDS sdhD NC_013008.1 837069 837416 D succinate dehydrogenase cytochrome b556 small membrane subunit 837069..837416 Escherichia coli O157:H7 str. TW14359 8215330 YP_003076706.1 CDS sdhA NC_013008.1 837416 839182 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 837416..839182 Escherichia coli O157:H7 str. TW14359 8215331 YP_003076707.1 CDS sdhB NC_013008.1 839198 839914 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 839198..839914 Escherichia coli O157:H7 str. TW14359 8215332 YP_003076708.1 CDS ECSP_0767 NC_013008.1 839948 840079 R hypothetical protein complement(839948..840079) Escherichia coli O157:H7 str. TW14359 8215333 YP_003076709.1 CDS sucA NC_013008.1 840215 843016 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 840215..843016 Escherichia coli O157:H7 str. TW14359 8215334 YP_003076710.1 CDS sucB NC_013008.1 843031 844248 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 843031..844248 Escherichia coli O157:H7 str. TW14359 8215335 YP_003076711.1 CDS sucC NC_013008.1 844342 845508 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 844342..845508 Escherichia coli O157:H7 str. TW14359 8215336 YP_003076712.1 CDS sucD NC_013008.1 845508 846377 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 845508..846377 Escherichia coli O157:H7 str. TW14359 8215337 YP_003076713.1 CDS ECSP_0772 NC_013008.1 846627 846773 D histidine ammonia-lyase 846627..846773 Escherichia coli O157:H7 str. TW14359 8215338 YP_003076714.1 CDS ECSP_0773 NC_013008.1 847044 847949 D LysR family transcriptional regulator 847044..847949 Escherichia coli O157:H7 str. TW14359 8215339 YP_003076715.1 CDS ECSP_0774 NC_013008.1 847983 848585 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(847983..848585) Escherichia coli O157:H7 str. TW14359 8215340 YP_003076716.1 CDS ECSP_0775 NC_013008.1 848595 850247 R fumarate hydratase complement(848595..850247) Escherichia coli O157:H7 str. TW14359 8215341 YP_003076717.1 CDS ECSP_0776 NC_013008.1 850355 851635 R symport protein complement(850355..851635) Escherichia coli O157:H7 str. TW14359 8215342 YP_003076718.1 CDS ECSP_0777 NC_013008.1 851796 852113 R hypothetical protein complement(851796..852113) Escherichia coli O157:H7 str. TW14359 8215343 YP_003076719.1 CDS ECSP_0778 NC_013008.1 852110 853480 R hypothetical protein complement(852110..853480) Escherichia coli O157:H7 str. TW14359 8215344 YP_003076720.1 CDS ECSP_0779 NC_013008.1 853484 854725 R methylaspartate ammonia-lyase complement(853484..854725) Escherichia coli O157:H7 str. TW14359 8215345 YP_003076721.1 CDS ECSP_0780 NC_013008.1 854725 856170 R glutamate mutase subumit E complement(854725..856170) Escherichia coli O157:H7 str. TW14359 8215346 YP_003076722.1 CDS ECSP_0781 NC_013008.1 856189 857577 R hypothetical protein complement(856189..857577) Escherichia coli O157:H7 str. TW14359 8215347 YP_003076723.1 CDS ECSP_0782 NC_013008.1 857577 858026 R converts methylaspartate to L-glutamate; methylaspartate mutase subunit S complement(857577..858026) Escherichia coli O157:H7 str. TW14359 8215348 YP_003076724.1 CDS ECSP_0783 NC_013008.1 858213 858380 R hypothetical protein complement(858213..858380) Escherichia coli O157:H7 str. TW14359 8215349 YP_003076725.1 CDS ECSP_0784 NC_013008.1 858574 858996 R hypothetical protein complement(858574..858996) Escherichia coli O157:H7 str. TW14359 8215350 YP_003076726.1 CDS ECSP_0785 NC_013008.1 859078 860022 R hypothetical protein complement(859078..860022) Escherichia coli O157:H7 str. TW14359 8215351 YP_003076727.1 CDS cydA NC_013008.1 860828 862396 D cytochrome d terminal oxidase subunit I 860828..862396 Escherichia coli O157:H7 str. TW14359 8215352 YP_003076728.1 CDS cydB NC_013008.1 862412 863551 D cytochrome d terminal oxidase subunit II 862412..863551 Escherichia coli O157:H7 str. TW14359 8215353 YP_003076729.1 CDS ybgE NC_013008.1 863679 863972 D hypothetical protein 863679..863972 Escherichia coli O157:H7 str. TW14359 8215354 YP_003076730.1 CDS ybgC NC_013008.1 864122 864526 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 864122..864526 Escherichia coli O157:H7 str. TW14359 8215355 YP_003076731.1 CDS tolQ NC_013008.1 864523 865215 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 864523..865215 Escherichia coli O157:H7 str. TW14359 8215356 YP_003076732.1 CDS tolR NC_013008.1 865219 865647 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 865219..865647 Escherichia coli O157:H7 str. TW14359 8215357 YP_003076733.1 CDS tolA NC_013008.1 865712 866986 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 865712..866986 Escherichia coli O157:H7 str. TW14359 8215358 YP_003076734.1 CDS tolB NC_013008.1 867119 868411 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 867119..868411 Escherichia coli O157:H7 str. TW14359 8215359 YP_003076735.1 CDS pal NC_013008.1 868446 868967 D peptidoglycan-associated outer membrane lipoprotein 868446..868967 Escherichia coli O157:H7 str. TW14359 8215360 YP_003076736.1 CDS ybgF NC_013008.1 868977 869768 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 868977..869768 Escherichia coli O157:H7 str. TW14359 8215361 YP_003076737.1 CDS nadA NC_013008.1 870903 871946 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 870903..871946 Escherichia coli O157:H7 str. TW14359 8215368 YP_003076738.1 CDS pnuC NC_013008.1 871984 872703 D nicotinamide mononucleotide transporter 871984..872703 Escherichia coli O157:H7 str. TW14359 8215369 YP_003076739.1 CDS zitB NC_013008.1 872700 873641 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(872700..873641) Escherichia coli O157:H7 str. TW14359 8215370 YP_003076740.1 CDS ybgS NC_013008.1 873755 874135 R hypothetical protein complement(873755..874135) Escherichia coli O157:H7 str. TW14359 8215371 YP_003076741.1 CDS aroG NC_013008.1 874451 875503 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 874451..875503 Escherichia coli O157:H7 str. TW14359 8215372 YP_003076742.1 CDS gpmA NC_013008.1 875669 876421 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(875669..876421) Escherichia coli O157:H7 str. TW14359 8215373 YP_003076743.1 CDS ECSP_0808 NC_013008.1 876495 876623 R hypothetical protein complement(876495..876623) Escherichia coli O157:H7 str. TW14359 8215374 YP_003076744.1 CDS galM NC_013008.1 876623 877663 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(876623..877663) Escherichia coli O157:H7 str. TW14359 8215375 YP_003076745.1 CDS galK NC_013008.1 877657 878805 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(877657..878805) Escherichia coli O157:H7 str. TW14359 8215376 YP_003076746.1 CDS galT NC_013008.1 878809 879855 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(878809..879855) Escherichia coli O157:H7 str. TW14359 8215377 YP_003076747.1 CDS galE NC_013008.1 879865 880881 R UDP-galactose-4-epimerase complement(879865..880881) Escherichia coli O157:H7 str. TW14359 8215378 YP_003076748.1 CDS modF NC_013008.1 881143 882615 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(881143..882615) Escherichia coli O157:H7 str. TW14359 8215379 YP_003076749.1 CDS modE NC_013008.1 882683 883471 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(882683..883471) Escherichia coli O157:H7 str. TW14359 8215380 YP_003076750.1 CDS ybhT NC_013008.1 883600 883749 D hypothetical protein 883600..883749 Escherichia coli O157:H7 str. TW14359 8215381 YP_003076751.1 CDS modA NC_013008.1 883916 884689 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 883916..884689 Escherichia coli O157:H7 str. TW14359 8215382 YP_003076752.1 CDS modB NC_013008.1 884689 885378 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 884689..885378 Escherichia coli O157:H7 str. TW14359 8215383 YP_003076753.1 CDS modC NC_013008.1 885381 886439 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 885381..886439 Escherichia coli O157:H7 str. TW14359 8215384 YP_003076754.1 CDS ybhA NC_013008.1 886440 887258 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(886440..887258) Escherichia coli O157:H7 str. TW14359 8215385 YP_003076755.1 CDS pgl NC_013008.1 887413 888408 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 887413..888408 Escherichia coli O157:H7 str. TW14359 8215386 YP_003076756.1 CDS ybhD NC_013008.1 888449 889402 R DNA-binding transcriptional regulator complement(888449..889402) Escherichia coli O157:H7 str. TW14359 8215387 YP_003076757.1 CDS ybhH NC_013008.1 889586 890638 D hypothetical protein 889586..890638 Escherichia coli O157:H7 str. TW14359 8215388 YP_003076758.1 CDS ybhI NC_013008.1 890714 892147 D transporter 890714..892147 Escherichia coli O157:H7 str. TW14359 8215389 YP_003076759.1 CDS ybhJ NC_013008.1 892330 894591 D hypothetical protein 892330..894591 Escherichia coli O157:H7 str. TW14359 8215390 YP_003076760.1 CDS ybhC NC_013008.1 894732 896015 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase complement(894732..896015) Escherichia coli O157:H7 str. TW14359 8215391 YP_003076761.1 CDS ECSP_0826 NC_013008.1 896150 896920 R integrase encoded by prophage CP-933K complement(896150..896920) Escherichia coli O157:H7 str. TW14359 8215392 YP_003076762.1 CDS ECSP_0827 NC_013008.1 897198 897416 R excisionase complement(897198..897416) Escherichia coli O157:H7 str. TW14359 8215393 YP_003076763.1 CDS ECSP_0828 NC_013008.1 897456 897623 R hypothetical protein complement(897456..897623) Escherichia coli O157:H7 str. TW14359 8215394 YP_003076764.1 CDS ECSP_0829 NC_013008.1 897866 898468 D hypothetical protein 897866..898468 Escherichia coli O157:H7 str. TW14359 8215395 YP_003076765.1 CDS ECSP_0830 NC_013008.1 898999 899214 R hypothetical protein complement(898999..899214) Escherichia coli O157:H7 str. TW14359 8215396 YP_003076766.1 CDS ECSP_0831 NC_013008.1 899291 899482 R hypothetical protein complement(899291..899482) Escherichia coli O157:H7 str. TW14359 8215397 YP_003076767.1 CDS ECSP_0832 NC_013008.1 899634 900314 R exonuclease encoded by prophage CP-933K complement(899634..900314) Escherichia coli O157:H7 str. TW14359 8215398 YP_003076768.1 CDS ECSP_0833 NC_013008.1 900311 900958 R Bet recombination protein of prophage CP-933K complement(900311..900958) Escherichia coli O157:H7 str. TW14359 8215399 YP_003076769.1 CDS ECSP_0834 NC_013008.1 901351 901974 D hypothetical protein 901351..901974 Escherichia coli O157:H7 str. TW14359 8215400 YP_003076770.1 CDS ECSP_0835 NC_013008.1 902205 902636 D hypothetical protein 902205..902636 Escherichia coli O157:H7 str. TW14359 8215401 YP_003076771.1 CDS ECSP_0836 NC_013008.1 902848 903807 R hypothetical protein complement(902848..903807) Escherichia coli O157:H7 str. TW14359 8215402 YP_003076772.1 CDS ECSP_0837 NC_013008.1 904282 904971 D antiterminator Q protein of prophage CP-933K 904282..904971 Escherichia coli O157:H7 str. TW14359 8215403 YP_003076773.1 CDS ECSP_0838 NC_013008.1 905182 905898 D hypothetical protein 905182..905898 Escherichia coli O157:H7 str. TW14359 8215404 YP_003076774.1 CDS ECSP_0839 NC_013008.1 906041 906142 D hypothetical protein 906041..906142 Escherichia coli O157:H7 str. TW14359 8215405 YP_003076776.1 CDS ECSP_0841 NC_013008.1 906979 907476 D lysozyme protein R of prophage CP-933K 906979..907476 Escherichia coli O157:H7 str. TW14359 8215407 YP_003076777.1 CDS ECSP_0842 NC_013008.1 907473 907940 D endopeptidase protein Rz of prophage CP-933K 907473..907940 Escherichia coli O157:H7 str. TW14359 8215408 YP_003076778.1 CDS ECSP_0843 NC_013008.1 908439 908624 R hypothetical protein complement(908439..908624) Escherichia coli O157:H7 str. TW14359 8215409 YP_003076779.1 CDS ECSP_0844 NC_013008.1 908755 909246 D hypothetical protein 908755..909246 Escherichia coli O157:H7 str. TW14359 8215410 YP_003076780.1 CDS ECSP_0845 NC_013008.1 909246 911348 D DNA packaging protein of prophage CP-933K 909246..911348 Escherichia coli O157:H7 str. TW14359 8215411 YP_003076781.1 CDS ECSP_0846 NC_013008.1 911485 912609 D hypothetical protein 911485..912609 Escherichia coli O157:H7 str. TW14359 8215412 YP_003076782.1 CDS ECSP_0847 NC_013008.1 912704 913066 D hypothetical protein 912704..913066 Escherichia coli O157:H7 str. TW14359 8215413 YP_003076783.1 CDS ECSP_0848 NC_013008.1 913080 915038 D protease encoded in prophage CP-933K 913080..915038 Escherichia coli O157:H7 str. TW14359 8215414 YP_003076784.1 CDS ECSP_0849 NC_013008.1 915125 915448 D hypothetical protein 915125..915448 Escherichia coli O157:H7 str. TW14359 8215415 YP_003076785.1 CDS ECSP_0850 NC_013008.1 915441 915716 D hypothetical protein 915441..915716 Escherichia coli O157:H7 str. TW14359 8215416 YP_003076786.1 CDS ECSP_0851 NC_013008.1 915728 916306 D tail component of prophage CP-933K 915728..916306 Escherichia coli O157:H7 str. TW14359 8215417 YP_003076787.1 CDS ECSP_0852 NC_013008.1 916303 916704 D tail component of prophage CP-933K 916303..916704 Escherichia coli O157:H7 str. TW14359 8215418 YP_003076788.1 CDS ECSP_0853 NC_013008.1 916715 917458 D tail component of prophage CP-933K 916715..917458 Escherichia coli O157:H7 str. TW14359 8215419 YP_003076789.1 CDS ECSP_0854 NC_013008.1 917516 917905 D tail component of prophage CP-933K 917516..917905 Escherichia coli O157:H7 str. TW14359 8215420 YP_003076790.1 CDS ECSP_0855 NC_013008.1 917914 918243 D tail component of prophage CP-933K 917914..918243 Escherichia coli O157:H7 str. TW14359 8215421 YP_003076791.1 CDS ECSP_0856 NC_013008.1 918215 921280 D tail component of prophage CP-933K 918215..921280 Escherichia coli O157:H7 str. TW14359 8215422 YP_003076792.1 CDS ECSP_0857 NC_013008.1 921280 921609 D tail component of prophage CP-933K 921280..921609 Escherichia coli O157:H7 str. TW14359 8215423 YP_003076793.1 CDS ECSP_0858 NC_013008.1 921619 922317 D tail component of prophage CP-933K 921619..922317 Escherichia coli O157:H7 str. TW14359 8215424 YP_003076794.1 CDS ECSP_0859 NC_013008.1 922323 923066 D tail component of prophage CP-933K 922323..923066 Escherichia coli O157:H7 str. TW14359 8215425 YP_003076795.1 CDS ECSP_0860 NC_013008.1 922964 923611 D tail component of prophage CP-933K 922964..923611 Escherichia coli O157:H7 str. TW14359 8215426 YP_003076796.1 CDS ECSP_0861 NC_013008.1 923672 927085 D tail component of prophage CP-933K 923672..927085 Escherichia coli O157:H7 str. TW14359 8215427 YP_003076797.1 CDS lomK NC_013008.1 927156 927755 D outer membrane protein of prophage CP-933K 927156..927755 Escherichia coli O157:H7 str. TW14359 8215428 YP_003076798.1 CDS ECSP_0863 NC_013008.1 927815 929131 D tail component of prophage CP-933K 927815..929131 Escherichia coli O157:H7 str. TW14359 8215429 YP_003076799.1 CDS ECSP_0864 NC_013008.1 929094 929402 D hypothetical protein 929094..929402 Escherichia coli O157:H7 str. TW14359 8215430 YP_003076800.1 CDS nleB1 NC_013008.1 929579 930559 D non-LEE-encoded type III effector 929579..930559 Escherichia coli O157:H7 str. TW14359 8215431 YP_003076801.1 CDS nleC NC_013008.1 930620 931612 D non-LEE-encoded type III effector 930620..931612 Escherichia coli O157:H7 str. TW14359 8215432 YP_003076802.1 CDS nleH1 NC_013008.1 932440 933321 D non-LEE-encoded type III effector 932440..933321 Escherichia coli O157:H7 str. TW14359 8215433 YP_003076803.1 CDS nleD NC_013008.1 933552 934250 D non-LEE-encoded type III effector 933552..934250 Escherichia coli O157:H7 str. TW14359 8215434 YP_003076804.1 CDS ybhB NC_013008.1 934757 935233 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(934757..935233) Escherichia coli O157:H7 str. TW14359 8215435 YP_003076805.1 CDS bioA NC_013008.1 935292 936581 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(935292..936581) Escherichia coli O157:H7 str. TW14359 8215436 YP_003076806.1 CDS bioB NC_013008.1 936668 937708 D biotin synthase 936668..937708 Escherichia coli O157:H7 str. TW14359 8215437 YP_003076807.1 CDS bioF NC_013008.1 937705 938859 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 937705..938859 Escherichia coli O157:H7 str. TW14359 8215438 YP_003076808.1 CDS bioC NC_013008.1 938846 939601 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 938846..939601 Escherichia coli O157:H7 str. TW14359 8215439 YP_003076809.1 CDS bioD NC_013008.1 939594 940271 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 939594..940271 Escherichia coli O157:H7 str. TW14359 8215440 YP_003076810.1 CDS uvrB NC_013008.1 940850 942871 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 940850..942871 Escherichia coli O157:H7 str. TW14359 8215441 YP_003076811.1 CDS ybhK NC_013008.1 943062 943970 R transferase with NAD(P)-binding Rossmann-fold domain complement(943062..943970) Escherichia coli O157:H7 str. TW14359 8215442 YP_003076812.1 CDS moaA NC_013008.1 944367 945356 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 944367..945356 Escherichia coli O157:H7 str. TW14359 8215443 YP_003076813.1 CDS moaB NC_013008.1 945378 945890 D molybdopterin biosynthesis protein B 945378..945890 Escherichia coli O157:H7 str. TW14359 8215444 YP_003076814.1 CDS moaC NC_013008.1 945893 946378 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 945893..946378 Escherichia coli O157:H7 str. TW14359 8215445 YP_003076815.1 CDS moaD NC_013008.1 946371 946616 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 946371..946616 Escherichia coli O157:H7 str. TW14359 8215446 YP_003076816.1 CDS moaE NC_013008.1 946618 947070 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 946618..947070 Escherichia coli O157:H7 str. TW14359 8215447 YP_003076817.1 CDS ybhL NC_013008.1 947206 947910 D inner membrane protein 947206..947910 Escherichia coli O157:H7 str. TW14359 8215448 YP_003076818.1 CDS ybhM NC_013008.1 948118 948831 D hypothetical protein 948118..948831 Escherichia coli O157:H7 str. TW14359 8215449 YP_003076819.1 CDS ybhN NC_013008.1 948867 949823 R hypothetical protein complement(948867..949823) Escherichia coli O157:H7 str. TW14359 8215450 YP_003076820.1 CDS ybhO NC_013008.1 949823 951064 R cardiolipin synthase 2 complement(949823..951064) Escherichia coli O157:H7 str. TW14359 8215451 YP_003076821.1 CDS ybhP NC_013008.1 951061 951822 R DNase complement(951061..951822) Escherichia coli O157:H7 str. TW14359 8215452 YP_003076822.1 CDS ybhQ NC_013008.1 951955 952365 D inner membrane protein 951955..952365 Escherichia coli O157:H7 str. TW14359 8215453 YP_003076823.1 CDS ybhR NC_013008.1 952327 953433 R ABC transporter membrane protein complement(952327..953433) Escherichia coli O157:H7 str. TW14359 8215454 YP_003076824.1 CDS ybhS NC_013008.1 953444 954577 R ABC transporter membrane protein complement(953444..954577) Escherichia coli O157:H7 str. TW14359 8215455 YP_003076825.1 CDS ybhF NC_013008.1 954570 956306 R fused transporter subunits of ABC superfamily: ATP-binding proteins complement(954570..956306) Escherichia coli O157:H7 str. TW14359 8215456 YP_003076826.1 CDS ybhG NC_013008.1 956299 957297 R hypothetical protein complement(956299..957297) Escherichia coli O157:H7 str. TW14359 8215457 YP_003076827.1 CDS ybiH NC_013008.1 957297 957968 R DNA-binding transcriptional regulator complement(957297..957968) Escherichia coli O157:H7 str. TW14359 8215458 YP_003076828.1 CDS rhlE NC_013008.1 958197 959564 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 958197..959564 Escherichia coli O157:H7 str. TW14359 8215459 YP_003076829.1 CDS ECSP_0894 NC_013008.1 959716 959859 D hypothetical protein 959716..959859 Escherichia coli O157:H7 str. TW14359 8215460 YP_003076830.1 CDS espX2 NC_013008.1 960172 962184 D non-LEE-encoded type III effector 960172..962184 Escherichia coli O157:H7 str. TW14359 8215461 YP_003076831.1 CDS dinG NC_013008.1 962468 964618 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 962468..964618 Escherichia coli O157:H7 str. TW14359 8215462 YP_003076832.1 CDS ybiB NC_013008.1 964646 965608 D glycosyl transferase family protein 964646..965608 Escherichia coli O157:H7 str. TW14359 8215463 YP_003076833.1 CDS ybiC NC_013008.1 965749 966834 D hypothetical protein 965749..966834 Escherichia coli O157:H7 str. TW14359 8215464 YP_003076834.1 CDS ybiJ NC_013008.1 967063 967323 R hypothetical protein complement(967063..967323) Escherichia coli O157:H7 str. TW14359 8215465 YP_003076835.1 CDS ybiI NC_013008.1 967566 967943 R hypothetical protein complement(967566..967943) Escherichia coli O157:H7 str. TW14359 8215466 YP_003076836.1 CDS ybiX NC_013008.1 967928 968614 R hydroxylase complement(967928..968614) Escherichia coli O157:H7 str. TW14359 8215467 YP_003076837.1 CDS fiu NC_013008.1 968656 970938 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(968656..970938) Escherichia coli O157:H7 str. TW14359 8215468 YP_003076838.1 CDS ybiM NC_013008.1 971203 971463 R hypothetical protein complement(971203..971463) Escherichia coli O157:H7 str. TW14359 8215469 YP_003076839.1 CDS ybiN NC_013008.1 971739 972665 D SAM-dependent methyltransferase 971739..972665 Escherichia coli O157:H7 str. TW14359 8215470 YP_003076840.1 CDS ybiO NC_013008.1 972662 974887 R hypothetical protein complement(972662..974887) Escherichia coli O157:H7 str. TW14359 8215471 YP_003076841.1 CDS glnQ NC_013008.1 975004 975726 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(975004..975726) Escherichia coli O157:H7 str. TW14359 8215472 YP_003076842.1 CDS glnP NC_013008.1 975723 976382 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(975723..976382) Escherichia coli O157:H7 str. TW14359 8215473 YP_003076843.1 CDS glnH NC_013008.1 976520 977266 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(976520..977266) Escherichia coli O157:H7 str. TW14359 8215474 YP_003076844.1 CDS dps NC_013008.1 977670 978173 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(977670..978173) Escherichia coli O157:H7 str. TW14359 8215475 YP_003076845.1 CDS ECSP_0910 NC_013008.1 978343 978441 R hypothetical protein complement(978343..978441) Escherichia coli O157:H7 str. TW14359 8215476 YP_003076846.1 CDS rhtA NC_013008.1 978472 979359 R threonine and homoserine efflux system complement(978472..979359) Escherichia coli O157:H7 str. TW14359 8215477 YP_003076847.1 CDS ompX NC_013008.1 979712 980227 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 979712..980227 Escherichia coli O157:H7 str. TW14359 8215478 YP_003076848.1 CDS ybiP NC_013008.1 980276 981859 R hydrolase complement(980276..981859) Escherichia coli O157:H7 str. TW14359 8215479 YP_003076849.1 CDS ECSP_0914 NC_013008.1 982131 982259 R hypothetical protein complement(982131..982259) Escherichia coli O157:H7 str. TW14359 8215480 YP_003076850.1 CDS mntR NC_013008.1 982445 982912 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 982445..982912 Escherichia coli O157:H7 str. TW14359 8215481 YP_003076851.1 CDS ybiR NC_013008.1 982909 984027 D transporter 982909..984027 Escherichia coli O157:H7 str. TW14359 8215482 YP_003076852.1 CDS ybiS NC_013008.1 984085 985005 R hypothetical protein complement(984085..985005) Escherichia coli O157:H7 str. TW14359 8215483 YP_003076853.1 CDS ybiT NC_013008.1 985224 986816 D ABC transporter with two ATP-binding domains 985224..986816 Escherichia coli O157:H7 str. TW14359 8215484 YP_003076854.1 CDS ybiU NC_013008.1 986984 988249 R hypothetical protein complement(986984..988249) Escherichia coli O157:H7 str. TW14359 8215485 YP_003076855.1 CDS ybiV NC_013008.1 988401 989216 R hydrolase complement(988401..989216) Escherichia coli O157:H7 str. TW14359 8215486 YP_003076856.1 CDS ybiY NC_013008.1 991799 992698 R pyruvate formate lyase activating enzyme complement(991799..992698) Escherichia coli O157:H7 str. TW14359 8215488 YP_003076857.1 CDS fsaA NC_013008.1 992829 993491 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 992829..993491 Escherichia coli O157:H7 str. TW14359 8215489 YP_003076858.1 CDS moeB NC_013008.1 993670 994419 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(993670..994419) Escherichia coli O157:H7 str. TW14359 8215490 YP_003076859.1 CDS moeA NC_013008.1 994419 995654 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(994419..995654) Escherichia coli O157:H7 str. TW14359 8215491 YP_003076860.1 CDS ECSP_0927 NC_013008.1 996810 998681 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 996810..998681 Escherichia coli O157:H7 str. TW14359 8215493 YP_003076861.1 CDS ECSP_0928 NC_013008.1 998701 1000239 D transport protein 998701..1000239 Escherichia coli O157:H7 str. TW14359 8215494 YP_003076862.1 CDS ECSP_0929 NC_013008.1 1000257 1001177 D transport system permease 1000257..1001177 Escherichia coli O157:H7 str. TW14359 8215495 YP_003076863.1 CDS ECSP_0930 NC_013008.1 1001180 1002091 D transport system permease 1001180..1002091 Escherichia coli O157:H7 str. TW14359 8215496 YP_003076864.1 CDS yliE NC_013008.1 1002269 1004617 D hypothetical protein 1002269..1004617 Escherichia coli O157:H7 str. TW14359 8215497 YP_003076865.1 CDS yliF NC_013008.1 1004625 1005953 D diguanylate cyclase 1004625..1005953 Escherichia coli O157:H7 str. TW14359 8215498 YP_003076866.1 CDS ECSP_0933 NC_013008.1 1006023 1006352 R hypothetical protein complement(1006023..1006352) Escherichia coli O157:H7 str. TW14359 8215499 YP_003076867.1 CDS ECSP_0934 NC_013008.1 1006342 1006728 R hypothetical protein complement(1006342..1006728) Escherichia coli O157:H7 str. TW14359 8215500 YP_003076868.1 CDS rimO NC_013008.1 1006954 1008279 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(1006954..1008279) Escherichia coli O157:H7 str. TW14359 8215501 YP_003076869.1 CDS bssR NC_013008.1 1008492 1008875 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1008492..1008875 Escherichia coli O157:H7 str. TW14359 8215502 YP_003076870.1 CDS yliI NC_013008.1 1008986 1010101 D dehydrogenase 1008986..1010101 Escherichia coli O157:H7 str. TW14359 8215503 YP_003076871.1 CDS yliJ NC_013008.1 1010098 1010724 R glutathione S-transferase complement(1010098..1010724) Escherichia coli O157:H7 str. TW14359 8215504 YP_003076872.1 CDS dacC NC_013008.1 1010970 1012172 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 1010970..1012172 Escherichia coli O157:H7 str. TW14359 8215505 YP_003076873.1 CDS deoR NC_013008.1 1012219 1012977 R DNA-binding transcriptional repressor DeoR complement(1012219..1012977) Escherichia coli O157:H7 str. TW14359 8215506 YP_003076874.1 CDS ybjG NC_013008.1 1013035 1013631 R UDP pyrophosphate phosphatase complement(1013035..1013631) Escherichia coli O157:H7 str. TW14359 8215507 YP_003076875.1 CDS cmr NC_013008.1 1013916 1015148 D multidrug efflux system protein 1013916..1015148 Escherichia coli O157:H7 str. TW14359 8215508 YP_003076876.1 CDS ybjH NC_013008.1 1015189 1015473 R hypothetical protein complement(1015189..1015473) Escherichia coli O157:H7 str. TW14359 8215509 YP_003076877.1 CDS ybjI NC_013008.1 1015559 1016374 R hypothetical protein complement(1015559..1016374) Escherichia coli O157:H7 str. TW14359 8215510 YP_003076878.1 CDS ybjJ NC_013008.1 1016374 1017582 R transporter complement(1016374..1017582) Escherichia coli O157:H7 str. TW14359 8215511 YP_003076879.1 CDS ybjK NC_013008.1 1017666 1018202 D DNA-binding transcriptional regulator 1017666..1018202 Escherichia coli O157:H7 str. TW14359 8215512 YP_003076880.1 CDS ybjL NC_013008.1 1018377 1020062 R hypothetical protein complement(1018377..1020062) Escherichia coli O157:H7 str. TW14359 8215513 YP_003076881.1 CDS ybjM NC_013008.1 1020332 1020709 D inner membrane protein 1020332..1020709 Escherichia coli O157:H7 str. TW14359 8215514 YP_003076882.1 CDS grxA NC_013008.1 1020739 1020996 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 complement(1020739..1020996) Escherichia coli O157:H7 str. TW14359 8215515 YP_003076883.1 CDS ybjC NC_013008.1 1021156 1021443 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1021156..1021443 Escherichia coli O157:H7 str. TW14359 8215516 YP_003076884.1 CDS nfsA NC_013008.1 1021427 1022149 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1021427..1022149 Escherichia coli O157:H7 str. TW14359 8215517 YP_003076885.1 CDS rimK NC_013008.1 1022210 1023112 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1022210..1023112 Escherichia coli O157:H7 str. TW14359 8215518 YP_003076886.1 CDS ybjN NC_013008.1 1023200 1023676 D oxidoreductase 1023200..1023676 Escherichia coli O157:H7 str. TW14359 8215519 YP_003076887.1 CDS potF NC_013008.1 1024027 1025139 D putrescine ABC transporter periplasmic-binding protein 1024027..1025139 Escherichia coli O157:H7 str. TW14359 8215520 YP_003076888.1 CDS potG NC_013008.1 1025234 1026367 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit 1025234..1026367 Escherichia coli O157:H7 str. TW14359 8215521 YP_003076889.1 CDS potH NC_013008.1 1026377 1027330 D putrescine ABC transporter membrane protein 1026377..1027330 Escherichia coli O157:H7 str. TW14359 8215522 YP_003076890.1 CDS potI NC_013008.1 1027327 1028172 D putrescine ABC transporter membrane protein 1027327..1028172 Escherichia coli O157:H7 str. TW14359 8215523 YP_003076891.1 CDS ybjO NC_013008.1 1028232 1028720 D inner membrane protein 1028232..1028720 Escherichia coli O157:H7 str. TW14359 8215524 YP_003076892.1 CDS rumB NC_013008.1 1028761 1029888 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1028761..1029888 Escherichia coli O157:H7 str. TW14359 8215525 YP_003076893.1 CDS ECSP_0960 NC_013008.1 1030168 1031511 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1030168..1031511 Escherichia coli O157:H7 str. TW14359 8215526 YP_003076894.1 CDS ECSP_0961 NC_013008.1 1031533 1031853 D hypothetical protein 1031533..1031853 Escherichia coli O157:H7 str. TW14359 8215527 YP_003076895.1 CDS ECSP_0962 NC_013008.1 1031865 1033346 D sulfatase 1031865..1033346 Escherichia coli O157:H7 str. TW14359 8215528 YP_003076896.1 CDS artJ NC_013008.1 1033397 1034128 R arginine ABC transporter substrate-binding protein complement(1033397..1034128) Escherichia coli O157:H7 str. TW14359 8215529 YP_003076897.1 CDS artM NC_013008.1 1034419 1035087 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(1034419..1035087) Escherichia coli O157:H7 str. TW14359 8215530 YP_003076898.1 CDS artQ NC_013008.1 1035087 1035803 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(1035087..1035803) Escherichia coli O157:H7 str. TW14359 8215531 YP_003076899.1 CDS artI NC_013008.1 1035810 1036541 R arginine ABC transporter substrate-binding protein complement(1035810..1036541) Escherichia coli O157:H7 str. TW14359 8215532 YP_003076900.1 CDS artP NC_013008.1 1036559 1037287 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(1036559..1037287) Escherichia coli O157:H7 str. TW14359 8215533 YP_003076901.1 CDS ybjP NC_013008.1 1037505 1038020 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(1037505..1038020) Escherichia coli O157:H7 str. TW14359 8215534 YP_003076902.1 CDS ECSP_0969 NC_013008.1 1038034 1038216 R hypothetical protein complement(1038034..1038216) Escherichia coli O157:H7 str. TW14359 8215535 YP_003076903.1 CDS ECSP_0970 NC_013008.1 1038644 1040443 D hypothetical protein 1038644..1040443 Escherichia coli O157:H7 str. TW14359 8215536 YP_003076904.1 CDS ybjQ NC_013008.1 1040654 1040977 D hypothetical protein 1040654..1040977 Escherichia coli O157:H7 str. TW14359 8215537 YP_003076905.1 CDS ybjR NC_013008.1 1040974 1041804 D amidase and lipoprotein 1040974..1041804 Escherichia coli O157:H7 str. TW14359 8215538 YP_003076906.1 CDS ybjS NC_013008.1 1041801 1042814 R NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain complement(1041801..1042814) Escherichia coli O157:H7 str. TW14359 8215539 YP_003076907.1 CDS ybjT NC_013008.1 1042913 1044343 R hypothetical protein complement(1042913..1044343) Escherichia coli O157:H7 str. TW14359 8215540 YP_003076908.1 CDS ltaE NC_013008.1 1044354 1045355 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(1044354..1045355) Escherichia coli O157:H7 str. TW14359 8215541 YP_003076909.1 CDS poxB NC_013008.1 1045392 1047110 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(1045392..1047110) Escherichia coli O157:H7 str. TW14359 8215542 YP_003076910.1 CDS hcr NC_013008.1 1047243 1048211 R HCP oxidoreductase, NADH-dependent complement(1047243..1048211) Escherichia coli O157:H7 str. TW14359 8215543 YP_003076911.1 CDS hcp NC_013008.1 1048223 1049875 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(1048223..1049875) Escherichia coli O157:H7 str. TW14359 8215544 YP_003076912.1 CDS ybjE NC_013008.1 1050019 1050918 R transporter complement(1050019..1050918) Escherichia coli O157:H7 str. TW14359 8215545 YP_003076913.1 CDS aqpZ NC_013008.1 1051376 1052071 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(1051376..1052071) Escherichia coli O157:H7 str. TW14359 8215546 YP_003076914.1 CDS ybjD NC_013008.1 1052497 1054155 D hypothetical protein 1052497..1054155 Escherichia coli O157:H7 str. TW14359 8215547 YP_003076915.1 CDS ybjX NC_013008.1 1054152 1055144 R hypothetical protein complement(1054152..1055144) Escherichia coli O157:H7 str. TW14359 8215548 YP_003076916.1 CDS macA NC_013008.1 1055259 1056374 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1055259..1056374 Escherichia coli O157:H7 str. TW14359 8215549 YP_003076917.1 CDS macB NC_013008.1 1056371 1058317 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1056371..1058317 Escherichia coli O157:H7 str. TW14359 8215550 YP_003076918.1 CDS cspD NC_013008.1 1058390 1058614 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(1058390..1058614) Escherichia coli O157:H7 str. TW14359 8215551 YP_003076919.1 CDS clpS NC_013008.1 1058937 1059257 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1058937..1059257 Escherichia coli O157:H7 str. TW14359 8215552 YP_003076920.1 CDS clpA NC_013008.1 1059288 1061564 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1059288..1061564 Escherichia coli O157:H7 str. TW14359 8215553 YP_003076921.1 CDS infA NC_013008.1 1062251 1062469 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1062251..1062469) Escherichia coli O157:H7 str. TW14359 8215555 YP_003076922.1 CDS aat NC_013008.1 1062754 1063458 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(1062754..1063458) Escherichia coli O157:H7 str. TW14359 8215556 YP_003076923.1 CDS cydC NC_013008.1 1063500 1065221 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1063500..1065221) Escherichia coli O157:H7 str. TW14359 8215557 YP_003076924.1 CDS cydD NC_013008.1 1065222 1066988 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1065222..1066988) Escherichia coli O157:H7 str. TW14359 8215558 YP_003076925.1 CDS trxB NC_013008.1 1067111 1068076 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(1067111..1068076) Escherichia coli O157:H7 str. TW14359 8215559 YP_003076926.1 CDS lrp NC_013008.1 1068621 1069115 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1068621..1069115 Escherichia coli O157:H7 str. TW14359 8215560 YP_003076927.1 CDS ftsK NC_013008.1 1069250 1073278 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 1069250..1073278 Escherichia coli O157:H7 str. TW14359 8215561 YP_003076928.1 CDS lolA NC_013008.1 1073433 1074044 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1073433..1074044 Escherichia coli O157:H7 str. TW14359 8215562 YP_003076929.1 CDS ycaJ NC_013008.1 1074055 1075398 D recombination factor protein RarA 1074055..1075398 Escherichia coli O157:H7 str. TW14359 8215563 YP_003076930.1 CDS serS NC_013008.1 1075489 1076781 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1075489..1076781 Escherichia coli O157:H7 str. TW14359 8215564 YP_003076931.1 CDS dmsA NC_013008.1 1077020 1079464 D dimethyl sulfoxide reductase subunit A 1077020..1079464 Escherichia coli O157:H7 str. TW14359 8215565 YP_003076932.1 CDS dmsB NC_013008.1 1079475 1080092 D dimethyl sulfoxide reductase subunit B 1079475..1080092 Escherichia coli O157:H7 str. TW14359 8215566 YP_003076933.1 CDS dmsC NC_013008.1 1080094 1080957 D dimethyl sulfoxide reductase subunit C 1080094..1080957 Escherichia coli O157:H7 str. TW14359 8215567 YP_003076934.1 CDS ycaC NC_013008.1 1080993 1081619 R hydrolase complement(1080993..1081619) Escherichia coli O157:H7 str. TW14359 8215568 YP_003076935.1 CDS ycaD NC_013008.1 1081934 1083082 D MFS family transporter protein 1081934..1083082 Escherichia coli O157:H7 str. TW14359 8215569 YP_003076936.1 CDS ycaM NC_013008.1 1083292 1084722 D transporter 1083292..1084722 Escherichia coli O157:H7 str. TW14359 8215570 YP_003076937.1 CDS ECSP_1005 NC_013008.1 1084726 1084845 D hypothetical protein 1084726..1084845 Escherichia coli O157:H7 str. TW14359 8215571 YP_003076938.1 CDS pflA NC_013008.1 1084932 1085672 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1084932..1085672) Escherichia coli O157:H7 str. TW14359 8215572 YP_003076939.1 CDS pflB NC_013008.1 1085864 1088146 R pyruvate formate lyase I complement(1085864..1088146) Escherichia coli O157:H7 str. TW14359 8215573 YP_003076940.1 CDS focA NC_013008.1 1088201 1089058 R formate transporter complement(1088201..1089058) Escherichia coli O157:H7 str. TW14359 8215574 YP_003076941.1 CDS ycaO NC_013008.1 1089464 1091224 R hypothetical protein complement(1089464..1091224) Escherichia coli O157:H7 str. TW14359 8215575 YP_003076942.1 CDS ycaP NC_013008.1 1091354 1092046 D hypothetical protein 1091354..1092046 Escherichia coli O157:H7 str. TW14359 8215576 YP_003076943.1 CDS serC NC_013008.1 1092245 1093333 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1092245..1093333 Escherichia coli O157:H7 str. TW14359 8215577 YP_003076944.1 CDS aroA NC_013008.1 1093404 1094687 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1093404..1094687 Escherichia coli O157:H7 str. TW14359 8215578 YP_003076945.1 CDS ycaL NC_013008.1 1094856 1095620 D peptidase 1094856..1095620 Escherichia coli O157:H7 str. TW14359 8215579 YP_003076946.1 CDS cmk NC_013008.1 1095793 1096476 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1095793..1096476 Escherichia coli O157:H7 str. TW14359 8215580 YP_003076947.1 CDS rpsA NC_013008.1 1096587 1098260 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1096587..1098260 Escherichia coli O157:H7 str. TW14359 8215581 YP_003076948.1 CDS ihfB NC_013008.1 1098420 1098704 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1098420..1098704 Escherichia coli O157:H7 str. TW14359 8215582 YP_003076949.1 CDS ycaI NC_013008.1 1098911 1101175 D hypothetical protein 1098911..1101175 Escherichia coli O157:H7 str. TW14359 8215583 YP_003076950.1 CDS msbA NC_013008.1 1101212 1102960 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1101212..1102960 Escherichia coli O157:H7 str. TW14359 8215584 YP_003076951.1 CDS lpxK NC_013008.1 1102957 1103943 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1102957..1103943 Escherichia coli O157:H7 str. TW14359 8215585 YP_003076952.1 CDS ycaQ NC_013008.1 1103980 1105212 D hypothetical protein 1103980..1105212 Escherichia coli O157:H7 str. TW14359 8215586 YP_003076953.1 CDS ycaR NC_013008.1 1105264 1105446 D hypothetical protein 1105264..1105446 Escherichia coli O157:H7 str. TW14359 8215587 YP_003076954.1 CDS kdsB NC_013008.1 1105443 1106189 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1105443..1106189 Escherichia coli O157:H7 str. TW14359 8215588 YP_003076955.1 CDS ycbJ NC_013008.1 1106343 1107236 D hypothetical protein 1106343..1107236 Escherichia coli O157:H7 str. TW14359 8215589 YP_003076956.1 CDS ycbC NC_013008.1 1107213 1107992 R hypothetical protein complement(1107213..1107992) Escherichia coli O157:H7 str. TW14359 8215590 YP_003076957.1 CDS smtA NC_013008.1 1108128 1108913 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1108128..1108913 Escherichia coli O157:H7 str. TW14359 8215591 YP_003076958.1 CDS mukF NC_013008.1 1108910 1110232 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1108910..1110232 Escherichia coli O157:H7 str. TW14359 8215592 YP_003076959.1 CDS mukE NC_013008.1 1110213 1110917 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1110213..1110917 Escherichia coli O157:H7 str. TW14359 8215593 YP_003076960.1 CDS mukB NC_013008.1 1110917 1115377 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1110917..1115377 Escherichia coli O157:H7 str. TW14359 8215594 YP_003076961.1 CDS ycbB NC_013008.1 1115638 1117485 D hypothetical protein 1115638..1117485 Escherichia coli O157:H7 str. TW14359 8215595 YP_003076962.1 CDS ycbK NC_013008.1 1117666 1118214 D hypothetical protein 1117666..1118214 Escherichia coli O157:H7 str. TW14359 8215596 YP_003076963.1 CDS ycbL NC_013008.1 1118241 1118888 D metal-binding enzyme 1118241..1118888 Escherichia coli O157:H7 str. TW14359 8215597 YP_003076964.1 CDS aspC NC_013008.1 1118939 1120129 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1118939..1120129) Escherichia coli O157:H7 str. TW14359 8215598 YP_003076965.1 CDS ECSP_1033 NC_013008.1 1120203 1120301 R hypothetical protein complement(1120203..1120301) Escherichia coli O157:H7 str. TW14359 8215599 YP_003076966.1 CDS ompF NC_013008.1 1120314 1121402 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1120314..1121402) Escherichia coli O157:H7 str. TW14359 8215600 YP_003076967.1 CDS asnC NC_013008.1 1122005 1123405 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1122005..1123405) Escherichia coli O157:H7 str. TW14359 8215601 YP_003076968.1 CDS pncB NC_013008.1 1123574 1124776 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1123574..1124776) Escherichia coli O157:H7 str. TW14359 8215602 YP_003076969.1 CDS pepN NC_013008.1 1125042 1127654 D aminopeptidase 1125042..1127654 Escherichia coli O157:H7 str. TW14359 8215603 YP_003076970.1 CDS ssuB NC_013008.1 1127697 1128464 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1127697..1128464) Escherichia coli O157:H7 str. TW14359 8215604 YP_003076971.1 CDS ssuC NC_013008.1 1128461 1129252 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit complement(1128461..1129252) Escherichia coli O157:H7 str. TW14359 8215605 YP_003076972.1 CDS ssuD NC_013008.1 1129264 1130409 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1129264..1130409) Escherichia coli O157:H7 str. TW14359 8215606 YP_003076973.1 CDS ssuA NC_013008.1 1130406 1131365 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1130406..1131365) Escherichia coli O157:H7 str. TW14359 8215607 YP_003076974.1 CDS ssuE NC_013008.1 1131358 1131933 R NAD(P)H-dependent FMN reductase complement(1131358..1131933) Escherichia coli O157:H7 str. TW14359 8215608 YP_003076975.1 CDS ycbQ NC_013008.1 1132289 1132828 D fimbrial-like adhesin protein 1132289..1132828 Escherichia coli O157:H7 str. TW14359 8215609 YP_003076976.1 CDS ycbR NC_013008.1 1132911 1133612 D periplasmic pilin chaperone 1132911..1133612 Escherichia coli O157:H7 str. TW14359 8215610 YP_003076977.1 CDS ycbT NC_013008.1 1136227 1137207 D fimbrial-like adhesin protein 1136227..1137207 Escherichia coli O157:H7 str. TW14359 8215612 YP_003076978.1 CDS ECSP_1047 NC_013008.1 1137208 1137297 D hypothetical protein 1137208..1137297 Escherichia coli O157:H7 str. TW14359 8215613 YP_003076979.1 CDS ECSP_1048 NC_013008.1 1137400 1137852 D fimbrial-like adhesin protein 1137400..1137852 Escherichia coli O157:H7 str. TW14359 8215614 YP_003076980.1 CDS ycbV NC_013008.1 1137860 1138375 D fimbrial-like adhesin protein 1137860..1138375 Escherichia coli O157:H7 str. TW14359 8215615 YP_003076981.1 CDS ycbF NC_013008.1 1138368 1138910 D periplasmic pilin chaperone 1138368..1138910 Escherichia coli O157:H7 str. TW14359 8215616 YP_003076982.1 CDS pyrD NC_013008.1 1139188 1140198 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1139188..1140198 Escherichia coli O157:H7 str. TW14359 8215617 YP_003076983.1 CDS ycbW NC_013008.1 1140372 1140914 D hypothetical protein 1140372..1140914 Escherichia coli O157:H7 str. TW14359 8215618 YP_003076984.1 CDS ycbX NC_013008.1 1140911 1142020 R 2Fe-2S cluster-containing protein complement(1140911..1142020) Escherichia coli O157:H7 str. TW14359 8215619 YP_003076985.1 CDS rlmL NC_013008.1 1142264 1144372 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1142264..1144372 Escherichia coli O157:H7 str. TW14359 8215620 YP_003076986.1 CDS uup NC_013008.1 1144384 1146291 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1144384..1146291 Escherichia coli O157:H7 str. TW14359 8215621 YP_003076987.1 CDS pqiA NC_013008.1 1146421 1147674 D paraquat-inducible membrane protein A 1146421..1147674 Escherichia coli O157:H7 str. TW14359 8215622 YP_003076988.1 CDS pqiB NC_013008.1 1147679 1149319 D paraquat-inducible protein B 1147679..1149319 Escherichia coli O157:H7 str. TW14359 8215623 YP_003076989.1 CDS ymbA NC_013008.1 1149316 1149879 D hypothetical protein 1149316..1149879 Escherichia coli O157:H7 str. TW14359 8215624 YP_003076990.1 CDS rmf NC_013008.1 1150119 1150316 D ribosome modulation factor 1150119..1150316 Escherichia coli O157:H7 str. TW14359 8215625 YP_003076991.1 CDS fabA NC_013008.1 1150372 1150890 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1150372..1150890) Escherichia coli O157:H7 str. TW14359 8215626 YP_003076992.1 CDS ycbZ NC_013008.1 1150959 1152719 R peptidase complement(1150959..1152719) Escherichia coli O157:H7 str. TW14359 8215627 YP_003076993.1 CDS ycbG NC_013008.1 1152905 1153357 D hypothetical protein 1152905..1153357 Escherichia coli O157:H7 str. TW14359 8215628 YP_003076994.1 CDS ompA NC_013008.1 1153432 1154472 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1153432..1154472) Escherichia coli O157:H7 str. TW14359 8215629 YP_003076995.1 CDS sulA NC_013008.1 1154829 1155338 R SOS cell division inhibitor complement(1154829..1155338) Escherichia coli O157:H7 str. TW14359 8215630 YP_003076996.1 CDS sxy NC_013008.1 1155557 1156186 D CRP-S promoter co-activator 1155557..1156186 Escherichia coli O157:H7 str. TW14359 8215631 YP_003076997.1 CDS yccS NC_013008.1 1156149 1158302 R inner membrane protein complement(1156149..1158302) Escherichia coli O157:H7 str. TW14359 8215632 YP_003076998.1 CDS yccF NC_013008.1 1158321 1158767 R hypothetical protein complement(1158321..1158767) Escherichia coli O157:H7 str. TW14359 8215633 YP_003076999.1 CDS helD NC_013008.1 1158890 1160944 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1158890..1160944 Escherichia coli O157:H7 str. TW14359 8215634 YP_003077000.1 CDS mgsA NC_013008.1 1160976 1161434 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1160976..1161434) Escherichia coli O157:H7 str. TW14359 8215635 YP_003077001.1 CDS yccT NC_013008.1 1161530 1162192 R hypothetical protein complement(1161530..1162192) Escherichia coli O157:H7 str. TW14359 8215636 YP_003077002.1 CDS yccU NC_013008.1 1162365 1162778 D CoA-binding protein with NAD(P)-binding Rossmann-fold domain 1162365..1162778 Escherichia coli O157:H7 str. TW14359 8215637 YP_003077003.1 CDS hspQ NC_013008.1 1162823 1163140 R heat shock protein HspQ complement(1162823..1163140) Escherichia coli O157:H7 str. TW14359 8215638 YP_003077004.1 CDS yccW NC_013008.1 1163198 1164388 R methyltransferase complement(1163198..1164388) Escherichia coli O157:H7 str. TW14359 8215639 YP_003077005.1 CDS yccX NC_013008.1 1164483 1164761 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1164483..1164761 Escherichia coli O157:H7 str. TW14359 8215640 YP_003077006.1 CDS yccK NC_013008.1 1164758 1165087 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1164758..1165087) Escherichia coli O157:H7 str. TW14359 8215641 YP_003077007.1 CDS yccA NC_013008.1 1165178 1165837 R hypothetical protein complement(1165178..1165837) Escherichia coli O157:H7 str. TW14359 8215642 YP_003077008.1 CDS ECSP_1078 NC_013008.1 1167229 1167471 R hypothetical protein complement(1167229..1167471) Escherichia coli O157:H7 str. TW14359 8215644 YP_003077009.1 CDS ECSP_1079 NC_013008.1 1167539 1170010 R exodeoxyribonuclease VIII for cryptic prophage CP-933M complement(1167539..1170010) Escherichia coli O157:H7 str. TW14359 8215645 YP_003077010.1 CDS ECSP_1080 NC_013008.1 1170104 1170295 R hypothetical protein complement(1170104..1170295) Escherichia coli O157:H7 str. TW14359 8215646 YP_003077011.1 CDS ECSP_1081 NC_013008.1 1170292 1170480 R inhibitor of cell division encoded by cryptic prophage CP-933M complement(1170292..1170480) Escherichia coli O157:H7 str. TW14359 8215647 YP_003077012.1 CDS ECSP_1082 NC_013008.1 1171054 1171239 D hypothetical protein 1171054..1171239 Escherichia coli O157:H7 str. TW14359 8215648 YP_003077013.1 CDS ECSP_1083 NC_013008.1 1171426 1171815 R hypothetical protein complement(1171426..1171815) Escherichia coli O157:H7 str. TW14359 8215649 YP_003077014.1 CDS ECSP_1084 NC_013008.1 1171827 1171955 R hypothetical protein complement(1171827..1171955) Escherichia coli O157:H7 str. TW14359 8215650 YP_003077015.1 CDS ECSP_1085 NC_013008.1 1171957 1172112 R hypothetical protein complement(1171957..1172112) Escherichia coli O157:H7 str. TW14359 8215651 YP_003077016.1 CDS ECSP_1086 NC_013008.1 1172390 1172677 R hypothetical protein complement(1172390..1172677) Escherichia coli O157:H7 str. TW14359 8215652 YP_003077017.1 CDS ECSP_1087 NC_013008.1 1172677 1172868 R hypothetical protein complement(1172677..1172868) Escherichia coli O157:H7 str. TW14359 8215653 YP_003077018.1 CDS ECSP_1088 NC_013008.1 1172896 1173294 R encoded within cryptic prophage CP-933M; DicA-like protein, regulator of DicB complement(1172896..1173294) Escherichia coli O157:H7 str. TW14359 8215654 YP_003077019.1 CDS ECSP_1089 NC_013008.1 1173406 1173678 D hypothetical protein 1173406..1173678 Escherichia coli O157:H7 str. TW14359 8215655 YP_003077020.1 CDS ECSP_1090 NC_013008.1 1173662 1174087 D hypothetical protein 1173662..1174087 Escherichia coli O157:H7 str. TW14359 8215656 YP_003077021.1 CDS ECSP_1091 NC_013008.1 1174053 1174610 D hypothetical protein 1174053..1174610 Escherichia coli O157:H7 str. TW14359 8215657 YP_003077022.1 CDS ECSP_1092 NC_013008.1 1174717 1175925 D hypothetical protein 1174717..1175925 Escherichia coli O157:H7 str. TW14359 8215658 YP_003077023.1 CDS ECSP_1093 NC_013008.1 1175932 1176678 D replication protein 1175932..1176678 Escherichia coli O157:H7 str. TW14359 8215659 YP_003077024.1 CDS ECSP_1094 NC_013008.1 1176700 1177470 D hypothetical protein 1176700..1177470 Escherichia coli O157:H7 str. TW14359 8215660 YP_003077025.1 CDS ECSP_1095 NC_013008.1 1177486 1177899 D hypothetical protein 1177486..1177899 Escherichia coli O157:H7 str. TW14359 8215661 YP_003077026.1 CDS ECSP_1096 NC_013008.1 1178251 1179024 R hypothetical protein complement(1178251..1179024) Escherichia coli O157:H7 str. TW14359 8215662 YP_003077027.1 CDS ECSP_1097 NC_013008.1 1179629 1179784 D cell killing protein encoded within cryptic prophage CP-933M 1179629..1179784 Escherichia coli O157:H7 str. TW14359 8215663 YP_003077028.1 CDS ECSP_1098 NC_013008.1 1179952 1180230 D hypothetical protein 1179952..1180230 Escherichia coli O157:H7 str. TW14359 8215664 YP_003077029.1 CDS ECSP_1099 NC_013008.1 1180232 1181281 D hypothetical protein 1180232..1181281 Escherichia coli O157:H7 str. TW14359 8215665 YP_003077030.1 CDS ECSP_1100 NC_013008.1 1181294 1181665 D endonuclease of cryptic prophage CP-933M 1181294..1181665 Escherichia coli O157:H7 str. TW14359 8215666 YP_003077031.1 CDS ECSP_1101 NC_013008.1 1182178 1182996 D hypothetical protein 1182178..1182996 Escherichia coli O157:H7 str. TW14359 8215667 YP_003077032.1 CDS ECSP_1102 NC_013008.1 1183283 1183522 D hypothetical protein 1183283..1183522 Escherichia coli O157:H7 str. TW14359 8215668 YP_003077033.1 CDS ECSP_1103 NC_013008.1 1183617 1184330 D envelope protein encoded within prophage CP-933N 1183617..1184330 Escherichia coli O157:H7 str. TW14359 8215669 YP_003077034.1 CDS ECSP_1106 NC_013008.1 1185098 1186948 D hypothetical protein 1185098..1186948 Escherichia coli O157:H7 str. TW14359 8215672 YP_003077035.1 CDS ECSP_1107 NC_013008.1 1187124 1187450 D transposase 1187124..1187450 Escherichia coli O157:H7 str. TW14359 8215673 YP_003077036.1 CDS ECSP_1108 NC_013008.1 1187447 1188337 D transposase 1187447..1188337 Escherichia coli O157:H7 str. TW14359 8215674 YP_003077037.1 CDS ECSP_1109 NC_013008.1 1188542 1188856 R transcriptional regulator complement(1188542..1188856) Escherichia coli O157:H7 str. TW14359 8215675 YP_003077038.1 CDS ECSP_1110 NC_013008.1 1189322 1189789 R endopeptidase complement(1189322..1189789) Escherichia coli O157:H7 str. TW14359 8215676 YP_003077039.1 CDS ECSP_1111 NC_013008.1 1190125 1190658 R phage lysozyme complement(1190125..1190658) Escherichia coli O157:H7 str. TW14359 8215677 YP_003077040.1 CDS ECSP_1112 NC_013008.1 1190776 1191090 D hypothetical protein 1190776..1191090 Escherichia coli O157:H7 str. TW14359 8215678 YP_003077041.1 CDS ECSP_1113 NC_013008.1 1191346 1191552 R hypothetical protein complement(1191346..1191552) Escherichia coli O157:H7 str. TW14359 8215679 YP_003077042.1 CDS ECSP_1114 NC_013008.1 1191560 1191721 D hypothetical protein 1191560..1191721 Escherichia coli O157:H7 str. TW14359 8215680 YP_003077043.1 CDS ECSP_1115 NC_013008.1 1192303 1192578 D hypothetical protein 1192303..1192578 Escherichia coli O157:H7 str. TW14359 8215681 YP_003077044.1 CDS ECSP_1116 NC_013008.1 1192633 1193034 D hypothetical protein 1192633..1193034 Escherichia coli O157:H7 str. TW14359 8215682 YP_003077045.1 CDS ECSP_1117 NC_013008.1 1193031 1193378 D transposase ISEc8 1193031..1193378 Escherichia coli O157:H7 str. TW14359 8215683 YP_003077046.1 CDS ECSP_1118 NC_013008.1 1193428 1194966 D transposase ISEc8 1193428..1194966 Escherichia coli O157:H7 str. TW14359 8215684 YP_003077047.1 CDS ECSP_1121 NC_013008.1 1197346 1198938 D capsid protein 1197346..1198938 Escherichia coli O157:H7 str. TW14359 8215687 YP_003077048.1 CDS ECSP_1122 NC_013008.1 1198928 1200433 D capsid assembly protein 1198928..1200433 Escherichia coli O157:H7 str. TW14359 8215688 YP_003077049.1 CDS ECSP_1123 NC_013008.1 1200470 1200817 D capsid protein 1200470..1200817 Escherichia coli O157:H7 str. TW14359 8215689 YP_003077050.1 CDS ECSP_1124 NC_013008.1 1200875 1201141 D hypothetical protein 1200875..1201141 Escherichia coli O157:H7 str. TW14359 8215690 YP_003077051.1 CDS ECSP_1125 NC_013008.1 1201201 1201863 D tail fiber component 1201201..1201863 Escherichia coli O157:H7 str. TW14359 8215691 YP_003077052.1 CDS ECSP_1126 NC_013008.1 1201877 1202308 D tail component 1201877..1202308 Escherichia coli O157:H7 str. TW14359 8215692 YP_003077053.1 CDS ECSP_1127 NC_013008.1 1202359 1202748 D tail component 1202359..1202748 Escherichia coli O157:H7 str. TW14359 8215693 YP_003077054.1 CDS ECSP_1128 NC_013008.1 1202729 1205308 D tail component 1202729..1205308 Escherichia coli O157:H7 str. TW14359 8215694 YP_003077055.1 CDS ECSP_1129 NC_013008.1 1205305 1205634 D minor tail protein 1205305..1205634 Escherichia coli O157:H7 str. TW14359 8215695 YP_003077056.1 CDS ECSP_1130 NC_013008.1 1205634 1206332 D tail component 1205634..1206332 Escherichia coli O157:H7 str. TW14359 8215696 YP_003077057.1 CDS ECSP_1131 NC_013008.1 1206451 1207086 D tail fiber component 1206451..1207086 Escherichia coli O157:H7 str. TW14359 8215697 YP_003077058.1 CDS ECSP_1132 NC_013008.1 1207083 1207664 D tail assembly protein 1207083..1207664 Escherichia coli O157:H7 str. TW14359 8215698 YP_003077059.1 CDS ECSP_1133 NC_013008.1 1207855 1208514 R superoxide dismutase complement(1207855..1208514) Escherichia coli O157:H7 str. TW14359 8215699 YP_003077060.1 CDS ECSP_1134 NC_013008.1 1208516 1211989 D host specificity protein 1208516..1211989 Escherichia coli O157:H7 str. TW14359 8215700 YP_003077061.1 CDS ECSP_1135 NC_013008.1 1212057 1212656 D Ail/Lom family protein 1212057..1212656 Escherichia coli O157:H7 str. TW14359 8215701 YP_003077062.1 CDS ECSP_1136 NC_013008.1 1212678 1214033 D tail fiber protein 1212678..1214033 Escherichia coli O157:H7 str. TW14359 8215702 YP_003077063.1 CDS ECSP_1137 NC_013008.1 1213915 1214304 D hypothetical protein 1213915..1214304 Escherichia coli O157:H7 str. TW14359 8215703 YP_003077064.1 CDS ECSP_1138 NC_013008.1 1214429 1215181 R tir-cytoskeleton coupling protein complement(1214429..1215181) Escherichia coli O157:H7 str. TW14359 8215704 YP_003077065.1 CDS hyaA NC_013008.1 1216578 1217696 D hydrogenase 1, small subunit 1216578..1217696 Escherichia coli O157:H7 str. TW14359 8215706 YP_003077066.1 CDS hyaB NC_013008.1 1217693 1219486 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1217693..1219486 Escherichia coli O157:H7 str. TW14359 8215707 YP_003077067.1 CDS hyaC NC_013008.1 1219505 1220212 D hydrogenase 1 b-type cytochrome subunit 1219505..1220212 Escherichia coli O157:H7 str. TW14359 8215708 YP_003077068.1 CDS hyaD NC_013008.1 1220209 1220796 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1220209..1220796 Escherichia coli O157:H7 str. TW14359 8215709 YP_003077069.1 CDS hyaE NC_013008.1 1220793 1221191 D involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1220793..1221191 Escherichia coli O157:H7 str. TW14359 8215710 YP_003077070.1 CDS hyaF NC_013008.1 1221188 1222045 D protein involved in nickel incorporation into hydrogenase-1 proteins 1221188..1222045 Escherichia coli O157:H7 str. TW14359 8215711 YP_003077071.1 CDS appC NC_013008.1 1222179 1223723 D cytochrome bd-II oxidase subunit I 1222179..1223723 Escherichia coli O157:H7 str. TW14359 8215712 YP_003077072.1 CDS appB NC_013008.1 1223735 1224871 D cytochrome bd-II oxidase subunit II 1223735..1224871 Escherichia coli O157:H7 str. TW14359 8215713 YP_003077073.1 CDS ECSP_1148 NC_013008.1 1224884 1224976 D expressed during stationary phase; membrane protein 1224884..1224976 Escherichia coli O157:H7 str. TW14359 8215714 YP_003077074.1 CDS appA NC_013008.1 1225056 1226360 D phosphoanhydride phosphorylase 1225056..1226360 Escherichia coli O157:H7 str. TW14359 8215715 YP_003077075.1 CDS etk NC_013008.1 1226480 1228660 R cryptic autophosphorylating protein tyrosine kinase Etk complement(1226480..1228660) Escherichia coli O157:H7 str. TW14359 8215716 YP_003077076.1 CDS etp NC_013008.1 1228680 1229126 R Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase complement(1228680..1229126) Escherichia coli O157:H7 str. TW14359 8215717 YP_003077077.1 CDS yccZ NC_013008.1 1229114 1230253 R exopolysaccharide export protein complement(1229114..1230253) Escherichia coli O157:H7 str. TW14359 8215718 YP_003077078.1 CDS ymcA NC_013008.1 1230299 1232395 R hypothetical protein complement(1230299..1232395) Escherichia coli O157:H7 str. TW14359 8215719 YP_003077079.1 CDS ymcB NC_013008.1 1232395 1233141 R hypothetical protein complement(1232395..1233141) Escherichia coli O157:H7 str. TW14359 8215720 YP_003077080.1 CDS ymcC NC_013008.1 1233138 1233782 R outer membrane lipoprotein complement(1233138..1233782) Escherichia coli O157:H7 str. TW14359 8215721 YP_003077081.1 CDS ymcD NC_013008.1 1233889 1234194 R hypothetical protein complement(1233889..1234194) Escherichia coli O157:H7 str. TW14359 8215722 YP_003077082.1 CDS cspH NC_013008.1 1234636 1234848 R stress protein, member of the CspA-family complement(1234636..1234848) Escherichia coli O157:H7 str. TW14359 8215723 YP_003077083.1 CDS ECSP_1158 NC_013008.1 1234858 1234956 R hypothetical protein complement(1234858..1234956) Escherichia coli O157:H7 str. TW14359 8215724 YP_003077084.1 CDS cspG NC_013008.1 1235134 1235346 D cold shock protein CspG 1235134..1235346 Escherichia coli O157:H7 str. TW14359 8215725 YP_003077085.1 CDS ymcE NC_013008.1 1235520 1235750 D cold shock gene 1235520..1235750 Escherichia coli O157:H7 str. TW14359 8215726 YP_003077086.1 CDS yccM NC_013008.1 1235961 1237034 R 4Fe-4S membrane protein complement(1235961..1237034) Escherichia coli O157:H7 str. TW14359 8215727 YP_003077087.1 CDS torS NC_013008.1 1237106 1239850 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1237106..1239850) Escherichia coli O157:H7 str. TW14359 8215728 YP_003077088.1 CDS torT NC_013008.1 1239933 1240961 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1239933..1240961 Escherichia coli O157:H7 str. TW14359 8215729 YP_003077089.1 CDS torR NC_013008.1 1240934 1241626 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1240934..1241626) Escherichia coli O157:H7 str. TW14359 8215730 YP_003077090.1 CDS torC NC_013008.1 1241756 1242928 D trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1241756..1242928 Escherichia coli O157:H7 str. TW14359 8215731 YP_003077091.1 CDS torA NC_013008.1 1242928 1245474 D trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1242928..1245474 Escherichia coli O157:H7 str. TW14359 8215732 YP_003077092.1 CDS torD NC_013008.1 1245471 1246070 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1245471..1246070 Escherichia coli O157:H7 str. TW14359 8215733 YP_003077093.1 CDS cbpM NC_013008.1 1246224 1246529 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1246224..1246529) Escherichia coli O157:H7 str. TW14359 8215734 YP_003077094.1 CDS cbpA NC_013008.1 1246529 1247449 R functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1246529..1247449) Escherichia coli O157:H7 str. TW14359 8215735 YP_003077095.1 CDS ECSP_1171 NC_013008.1 1249120 1249236 D hypothetical protein 1249120..1249236 Escherichia coli O157:H7 str. TW14359 8215737 YP_003077096.1 CDS agp NC_013008.1 1249257 1250498 D glucose-1-phosphatase/inositol phosphatase 1249257..1250498 Escherichia coli O157:H7 str. TW14359 8215738 YP_003077097.1 CDS yccJ NC_013008.1 1250536 1250763 R hypothetical protein complement(1250536..1250763) Escherichia coli O157:H7 str. TW14359 8215739 YP_003077098.1 CDS wrbA NC_013008.1 1250784 1251329 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(1250784..1251329) Escherichia coli O157:H7 str. TW14359 8215740 YP_003077099.1 CDS ycdG NC_013008.1 1251942 1253270 R transport protein complement(1251942..1253270) Escherichia coli O157:H7 str. TW14359 8215741 YP_003077100.1 CDS ECSP_1176 NC_013008.1 1253291 1253785 R oxidoreductase complement(1253291..1253785) Escherichia coli O157:H7 str. TW14359 8215742 YP_003077101.1 CDS ECSP_1177 NC_013008.1 1253796 1254386 R hypothetical protein complement(1253796..1254386) Escherichia coli O157:H7 str. TW14359 8215743 YP_003077102.1 CDS ECSP_1178 NC_013008.1 1254396 1255196 R hydrolase complement(1254396..1255196) Escherichia coli O157:H7 str. TW14359 8215744 YP_003077103.1 CDS ECSP_1179 NC_013008.1 1255247 1255543 R hypothetical protein complement(1255247..1255543) Escherichia coli O157:H7 str. TW14359 8215745 YP_003077104.1 CDS ECSP_1180 NC_013008.1 1255555 1256247 R synthetase complement(1255555..1256247) Escherichia coli O157:H7 str. TW14359 8215746 YP_003077105.1 CDS ECSP_1181 NC_013008.1 1256247 1257395 R monooxygenase complement(1256247..1257395) Escherichia coli O157:H7 str. TW14359 8215747 YP_003077106.1 CDS ycdC NC_013008.1 1257626 1258264 D tet operon regulator 1257626..1258264 Escherichia coli O157:H7 str. TW14359 8215748 YP_003077107.1 CDS putA NC_013008.1 1258304 1262266 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1258304..1262266) Escherichia coli O157:H7 str. TW14359 8215749 YP_003077108.1 CDS putP NC_013008.1 1262689 1264197 D proline:sodium symporter 1262689..1264197 Escherichia coli O157:H7 str. TW14359 8215750 YP_003077109.1 CDS ECSP_1185 NC_013008.1 1264346 1265689 R hypothetical protein complement(1264346..1265689) Escherichia coli O157:H7 str. TW14359 8215751 YP_003077110.1 CDS ECSP_1186 NC_013008.1 1266252 1266398 D hypothetical protein 1266252..1266398 Escherichia coli O157:H7 str. TW14359 8215752 YP_003077111.1 CDS ECSP_1187 NC_013008.1 1266689 1266835 R hypothetical protein complement(1266689..1266835) Escherichia coli O157:H7 str. TW14359 8215753 YP_003077112.1 CDS efeU NC_013008.1 1266871 1267701 D ferrous iron permease 1266871..1267701 Escherichia coli O157:H7 str. TW14359 8215754 YP_003077113.1 CDS efeO NC_013008.1 1267759 1268886 D hypothetical protein 1267759..1268886 Escherichia coli O157:H7 str. TW14359 8215755 YP_003077114.1 CDS efeB NC_013008.1 1268892 1270163 D redox component of a tripartite ferrous iron transporter 1268892..1270163 Escherichia coli O157:H7 str. TW14359 8215756 YP_003077115.1 CDS phoH NC_013008.1 1270507 1271571 D hypothetical protein 1270507..1271571 Escherichia coli O157:H7 str. TW14359 8215757 YP_003077116.1 CDS pgaD NC_013008.1 1271621 1272034 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein complement(1271621..1272034) Escherichia coli O157:H7 str. TW14359 8215758 YP_003077117.1 CDS pgaC NC_013008.1 1272036 1273361 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1272036..1273361) Escherichia coli O157:H7 str. TW14359 8215759 YP_003077118.1 CDS pgaB NC_013008.1 1273354 1275372 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1273354..1275372) Escherichia coli O157:H7 str. TW14359 8215760 YP_003077119.1 CDS pgaA NC_013008.1 1275381 1277804 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1275381..1277804) Escherichia coli O157:H7 str. TW14359 8215761 YP_003077120.1 CDS ycdT NC_013008.1 1278391 1279749 D diguanylate cyclase 1278391..1279749 Escherichia coli O157:H7 str. TW14359 8215762 YP_003077121.1 CDS ECSP_1197 NC_013008.1 1279847 1281457 D hypothetical protein 1279847..1281457 Escherichia coli O157:H7 str. TW14359 8215763 YP_003077122.1 CDS ECSP_1198 NC_013008.1 1281559 1282050 R hypothetical protein complement(1281559..1282050) Escherichia coli O157:H7 str. TW14359 8215764 YP_003077123.1 CDS ECSP_1199 NC_013008.1 1282055 1282867 R hypothetical protein complement(1282055..1282867) Escherichia coli O157:H7 str. TW14359 8215765 YP_003077124.1 CDS ECSP_1200 NC_013008.1 1283546 1284337 D oxidoreductase 1283546..1284337 Escherichia coli O157:H7 str. TW14359 8215766 YP_003077125.1 CDS ECSP_1201 NC_013008.1 1284483 1285172 R chaperone complement(1284483..1285172) Escherichia coli O157:H7 str. TW14359 8215767 YP_003077126.1 CDS ECSP_1202 NC_013008.1 1285169 1286503 R fimbrial-like adhesion protein complement(1285169..1286503) Escherichia coli O157:H7 str. TW14359 8215768 YP_003077127.1 CDS ECSP_1203 NC_013008.1 1287381 1289036 R usher protein complement(1287381..1289036) Escherichia coli O157:H7 str. TW14359 8215769 YP_003077128.1 CDS ECSP_1204 NC_013008.1 1289089 1289790 R chaperone complement(1289089..1289790) Escherichia coli O157:H7 str. TW14359 8215770 YP_003077129.1 CDS ECSP_1205 NC_013008.1 1289876 1290436 R pilin subunit complement(1289876..1290436) Escherichia coli O157:H7 str. TW14359 8215771 YP_003077130.1 CDS ECSP_1206 NC_013008.1 1290479 1291102 R hypothetical protein complement(1290479..1291102) Escherichia coli O157:H7 str. TW14359 8215772 YP_003077131.1 CDS ECSP_1207 NC_013008.1 1291444 1291590 D hypothetical protein 1291444..1291590 Escherichia coli O157:H7 str. TW14359 8215773 YP_003077132.1 CDS ECSP_1208 NC_013008.1 1292284 1292436 D hypothetical protein 1292284..1292436 Escherichia coli O157:H7 str. TW14359 8215774 YP_003077133.1 CDS ECSP_1209 NC_013008.1 1292493 1296305 D member of ShlA/HecA/FhaA exoprotein family 1292493..1296305 Escherichia coli O157:H7 str. TW14359 8215775 YP_003077134.1 CDS ECSP_1210 NC_013008.1 1296394 1298013 D outer membrane transporter of ShlA/HecA/FhaA exoprotein family 1296394..1298013 Escherichia coli O157:H7 str. TW14359 8215776 YP_003077135.1 CDS ECSP_1211 NC_013008.1 1298029 1298397 D acyl carrier protein 1298029..1298397 Escherichia coli O157:H7 str. TW14359 8215777 YP_003077136.1 CDS ECSP_1212 NC_013008.1 1298417 1299172 D fatty acyl chain reductase 1298417..1299172 Escherichia coli O157:H7 str. TW14359 8215778 YP_003077137.1 CDS ECSP_1213 NC_013008.1 1299176 1299724 D fatty acyl chain dehydrase 1299176..1299724 Escherichia coli O157:H7 str. TW14359 8215779 YP_003077138.1 CDS ECSP_1214 NC_013008.1 1299746 1300027 D acyl carrier protein 1299746..1300027 Escherichia coli O157:H7 str. TW14359 8215780 YP_003077139.1 CDS ECSP_1215 NC_013008.1 1300063 1301223 D aminomethyltransferase 1300063..1301223 Escherichia coli O157:H7 str. TW14359 8215781 YP_003077140.1 CDS ECSP_1216 NC_013008.1 1301297 1303855 D beta-ketoacyl-[acyl carrier protein] synthase 1301297..1303855 Escherichia coli O157:H7 str. TW14359 8215782 YP_003077141.1 CDS ECSP_1217 NC_013008.1 1303860 1305083 D hypothetical protein 1303860..1305083 Escherichia coli O157:H7 str. TW14359 8215783 YP_003077142.1 CDS ECSP_1218 NC_013008.1 1305080 1306033 D hypothetical protein 1305080..1306033 Escherichia coli O157:H7 str. TW14359 8215784 YP_003077143.1 CDS ECSP_1219 NC_013008.1 1306044 1306751 D hypothetical protein 1306044..1306751 Escherichia coli O157:H7 str. TW14359 8215785 YP_003077144.1 CDS ECSP_1220 NC_013008.1 1306735 1307391 D hypothetical protein 1306735..1307391 Escherichia coli O157:H7 str. TW14359 8215786 YP_003077145.1 CDS ECSP_1221 NC_013008.1 1307392 1308702 D hypothetical protein 1307392..1308702 Escherichia coli O157:H7 str. TW14359 8215787 YP_003077146.1 CDS ECSP_1222 NC_013008.1 1308711 1309499 D hypothetical protein 1308711..1309499 Escherichia coli O157:H7 str. TW14359 8215788 YP_003077147.1 CDS ECSP_1223 NC_013008.1 1309496 1310884 D hypothetical protein 1309496..1310884 Escherichia coli O157:H7 str. TW14359 8215789 YP_003077148.1 CDS ymdE NC_013008.1 1310895 1311839 D acyl transferase 1310895..1311839 Escherichia coli O157:H7 str. TW14359 8215790 YP_003077149.1 CDS ycdU NC_013008.1 1311836 1312822 D inner membrane protein 1311836..1312822 Escherichia coli O157:H7 str. TW14359 8215791 YP_003077150.1 CDS ECSP_1226 NC_013008.1 1313189 1314391 D P4-family integrase 1313189..1314391 Escherichia coli O157:H7 str. TW14359 8215792 YP_003077151.1 CDS ECSP_1227 NC_013008.1 1314578 1316395 R hypothetical protein complement(1314578..1316395) Escherichia coli O157:H7 str. TW14359 8215793 YP_003077152.1 CDS ECSP_1229 NC_013008.1 1316891 1317328 D hypothetical protein 1316891..1317328 Escherichia coli O157:H7 str. TW14359 8215795 YP_003077153.1 CDS ECSP_1230 NC_013008.1 1317507 1317803 D prophage regulatory protein 1317507..1317803 Escherichia coli O157:H7 str. TW14359 8215796 YP_003077154.1 CDS ECSP_1231 NC_013008.1 1318030 1318227 D hypothetical protein 1318030..1318227 Escherichia coli O157:H7 str. TW14359 8215797 YP_003077155.1 CDS ECSP_1232 NC_013008.1 1318446 1319831 D hypothetical protein 1318446..1319831 Escherichia coli O157:H7 str. TW14359 8215798 YP_003077156.1 CDS ECSP_1233 NC_013008.1 1320727 1321614 R transposase complement(1320727..1321614) Escherichia coli O157:H7 str. TW14359 8215799 YP_003077157.1 CDS ECSP_1234 NC_013008.1 1321614 1321940 R transposase complement(1321614..1321940) Escherichia coli O157:H7 str. TW14359 8215800 YP_003077158.1 CDS ECSP_1235 NC_013008.1 1322001 1322528 D hypothetical protein 1322001..1322528 Escherichia coli O157:H7 str. TW14359 8215801 YP_003077159.1 CDS ECSP_1236 NC_013008.1 1322683 1325043 D helicase 1322683..1325043 Escherichia coli O157:H7 str. TW14359 8215802 YP_003077160.1 CDS ECSP_1237 NC_013008.1 1325205 1325474 R hypothetical protein complement(1325205..1325474) Escherichia coli O157:H7 str. TW14359 8215803 YP_003077161.1 CDS ECSP_1238 NC_013008.1 1325800 1327338 R transposase ISEc8 complement(1325800..1327338) Escherichia coli O157:H7 str. TW14359 8215804 YP_003077162.1 CDS ECSP_1239 NC_013008.1 1327388 1327735 R transposase ISEc8 complement(1327388..1327735) Escherichia coli O157:H7 str. TW14359 8215805 YP_003077163.1 CDS ECSP_1240 NC_013008.1 1327732 1328133 R hypothetical protein complement(1327732..1328133) Escherichia coli O157:H7 str. TW14359 8215806 YP_003077164.1 CDS ECSP_1241 NC_013008.1 1328188 1328499 R transposase complement(1328188..1328499) Escherichia coli O157:H7 str. TW14359 8215807 YP_003077165.1 CDS ECSP_1242 NC_013008.1 1328639 1329457 D transposase ISSd1 1328639..1329457 Escherichia coli O157:H7 str. TW14359 8215808 YP_003077166.1 CDS ECSP_1243 NC_013008.1 1329570 1330109 D complement resistance protein 1329570..1330109 Escherichia coli O157:H7 str. TW14359 8215809 YP_003077167.1 CDS ECSP_1245 NC_013008.1 1331408 1331767 D diacylglycerol kinase 1331408..1331767 Escherichia coli O157:H7 str. TW14359 8215811 YP_003077168.1 CDS ECSP_1246 NC_013008.1 1331860 1333479 R hypothetical protein complement(1331860..1333479) Escherichia coli O157:H7 str. TW14359 8215812 YP_003077169.1 CDS ECSP_1247 NC_013008.1 1333704 1333979 R hypothetical protein complement(1333704..1333979) Escherichia coli O157:H7 str. TW14359 8215813 YP_003077170.1 CDS ureD NC_013008.1 1334315 1335058 D urease accessory protein 1334315..1335058 Escherichia coli O157:H7 str. TW14359 8215814 YP_003077171.1 CDS ureA NC_013008.1 1335149 1335451 D UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1335149..1335451 Escherichia coli O157:H7 str. TW14359 8215815 YP_003077172.1 CDS ureB NC_013008.1 1335460 1335780 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 1335460..1335780 Escherichia coli O157:H7 str. TW14359 8215816 YP_003077173.1 CDS ureC NC_013008.1 1335770 1337476 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1335770..1337476 Escherichia coli O157:H7 str. TW14359 8215817 YP_003077174.1 CDS ureE NC_013008.1 1337486 1337950 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1337486..1337950 Escherichia coli O157:H7 str. TW14359 8215818 YP_003077175.1 CDS ureF NC_013008.1 1337951 1338625 D urease accessory protein F 1337951..1338625 Escherichia coli O157:H7 str. TW14359 8215819 YP_003077176.1 CDS ureG NC_013008.1 1338637 1339254 D GTP hydrolase 1338637..1339254 Escherichia coli O157:H7 str. TW14359 8215820 YP_003077177.1 CDS ECSP_1255 NC_013008.1 1339302 1339433 R hypothetical protein complement(1339302..1339433) Escherichia coli O157:H7 str. TW14359 8215821 YP_003077178.1 CDS ECSP_1256 NC_013008.1 1339510 1339851 R hypothetical protein complement(1339510..1339851) Escherichia coli O157:H7 str. TW14359 8215822 YP_003077179.1 CDS ECSP_1257 NC_013008.1 1339913 1340041 R hypothetical protein complement(1339913..1340041) Escherichia coli O157:H7 str. TW14359 8215823 YP_003077180.1 CDS rpmE2 NC_013008.1 1340466 1340729 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1340466..1340729 Escherichia coli O157:H7 str. TW14359 8215824 YP_003077181.1 CDS ECSP_1259 NC_013008.1 1340683 1341039 R hypothetical protein complement(1340683..1341039) Escherichia coli O157:H7 str. TW14359 8215825 YP_003077182.1 CDS ECSP_1260 NC_013008.1 1341031 1341171 D hypothetical protein 1341031..1341171 Escherichia coli O157:H7 str. TW14359 8215826 YP_003077183.1 CDS ECSP_1261 NC_013008.1 1341656 1342075 R colicin immunity protein complement(1341656..1342075) Escherichia coli O157:H7 str. TW14359 8215827 YP_003077184.1 CDS ECSP_1262 NC_013008.1 1342042 1342713 R hypothetical protein complement(1342042..1342713) Escherichia coli O157:H7 str. TW14359 8215828 YP_003077185.1 CDS ECSP_1263 NC_013008.1 1343118 1343252 D hypothetical protein 1343118..1343252 Escherichia coli O157:H7 str. TW14359 8215829 YP_003077186.1 CDS ECSP_1264 NC_013008.1 1343733 1343906 R hypothetical protein complement(1343733..1343906) Escherichia coli O157:H7 str. TW14359 8215830 YP_003077187.1 CDS ECSP_1265 NC_013008.1 1344246 1344863 R transposase complement(1344246..1344863) Escherichia coli O157:H7 str. TW14359 8215831 YP_003077188.1 CDS ECSP_1266 NC_013008.1 1345051 1345476 D hypothetical protein 1345051..1345476 Escherichia coli O157:H7 str. TW14359 8215832 YP_003077189.1 CDS ECSP_1267 NC_013008.1 1345473 1345823 D hypothetical protein 1345473..1345823 Escherichia coli O157:H7 str. TW14359 8215833 YP_003077190.1 CDS ECSP_1268 NC_013008.1 1345854 1347467 D hypothetical protein 1345854..1347467 Escherichia coli O157:H7 str. TW14359 8215834 YP_003077191.1 CDS ECSP_1269 NC_013008.1 1347471 1348328 R transposase, IS66 type complement(1347471..1348328) Escherichia coli O157:H7 str. TW14359 8215835 YP_003077192.1 CDS ECSP_1270 NC_013008.1 1348410 1348772 R transposase, ISEc8 type complement(1348410..1348772) Escherichia coli O157:H7 str. TW14359 8215836 YP_003077193.1 CDS ECSP_1271 NC_013008.1 1348738 1349067 R hypothetical protein complement(1348738..1349067) Escherichia coli O157:H7 str. TW14359 8215837 YP_003077194.1 CDS terW NC_013008.1 1349328 1349795 R hypothetical protein complement(1349328..1349795) Escherichia coli O157:H7 str. TW14359 8215838 YP_003077195.1 CDS ECSP_1273 NC_013008.1 1349813 1351021 R hypothetical protein complement(1349813..1351021) Escherichia coli O157:H7 str. TW14359 8215839 YP_003077196.1 CDS ECSP_1274 NC_013008.1 1351032 1353104 R hypothetical protein complement(1351032..1353104) Escherichia coli O157:H7 str. TW14359 8215840 YP_003077197.1 CDS ECSP_1275 NC_013008.1 1353070 1353843 R hypothetical protein complement(1353070..1353843) Escherichia coli O157:H7 str. TW14359 8215841 YP_003077198.1 CDS ECSP_1276 NC_013008.1 1353836 1354978 R hypothetical protein complement(1353836..1354978) Escherichia coli O157:H7 str. TW14359 8215842 YP_003077199.1 CDS ECSP_1277 NC_013008.1 1354988 1356046 R hypothetical protein complement(1354988..1356046) Escherichia coli O157:H7 str. TW14359 8215843 YP_003077200.1 CDS ECSP_1278 NC_013008.1 1356369 1356950 D phage inhibition, colicin resistance and tellurite resistance protein 1356369..1356950 Escherichia coli O157:H7 str. TW14359 8215844 YP_003077201.1 CDS terA NC_013008.1 1356950 1358107 D phage inhibition, colicin resistance and tellurite resistance protein 1356950..1358107 Escherichia coli O157:H7 str. TW14359 8215845 YP_003077202.1 CDS terB NC_013008.1 1358130 1358585 D phage inhibition, colicin resistance and tellurite resistance protein 1358130..1358585 Escherichia coli O157:H7 str. TW14359 8215846 YP_003077203.1 CDS terC NC_013008.1 1358608 1359648 D phage inhibition, colicin resistance and tellurite resistance protein 1358608..1359648 Escherichia coli O157:H7 str. TW14359 8215847 YP_003077204.1 CDS terD NC_013008.1 1359697 1360275 D phage inhibition, colicin resistance and tellurite resistance protein 1359697..1360275 Escherichia coli O157:H7 str. TW14359 8215848 YP_003077205.1 CDS terE NC_013008.1 1360344 1360919 D phage inhibition, colicin resistance and tellurite resistance protein 1360344..1360919 Escherichia coli O157:H7 str. TW14359 8215849 YP_003077206.1 CDS terF NC_013008.1 1361342 1361728 D phage inhibition, colicin resistance and tellurite resistance protein 1361342..1361728 Escherichia coli O157:H7 str. TW14359 8215850 YP_003077207.1 CDS iha NC_013008.1 1362242 1364332 R IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein complement(1362242..1364332) Escherichia coli O157:H7 str. TW14359 8215851 YP_003077208.1 CDS ECSP_1286 NC_013008.1 1364271 1364453 D hypothetical protein 1364271..1364453 Escherichia coli O157:H7 str. TW14359 8215852 YP_003077209.1 CDS ECSP_1288 NC_013008.1 1366636 1366971 D hypothetical protein 1366636..1366971 Escherichia coli O157:H7 str. TW14359 8215854 YP_003077210.1 CDS ECSP_1289 NC_013008.1 1367488 1367622 D hypothetical protein 1367488..1367622 Escherichia coli O157:H7 str. TW14359 8215855 YP_003077211.1 CDS ECSP_1290 NC_013008.1 1367752 1367946 R hypothetical protein complement(1367752..1367946) Escherichia coli O157:H7 str. TW14359 8215856 YP_003077212.1 CDS ECSP_1291 NC_013008.1 1368266 1368538 D hypothetical protein 1368266..1368538 Escherichia coli O157:H7 str. TW14359 8215857 YP_003077213.1 CDS ECSP_1292 NC_013008.1 1368770 1368925 D hypothetical protein 1368770..1368925 Escherichia coli O157:H7 str. TW14359 8215858 YP_003077214.1 CDS ECSP_1293 NC_013008.1 1369103 1369300 D hypothetical protein 1369103..1369300 Escherichia coli O157:H7 str. TW14359 8215859 YP_003077215.1 CDS ECSP_1294 NC_013008.1 1369384 1369503 D hypothetical protein 1369384..1369503 Escherichia coli O157:H7 str. TW14359 8215860 YP_003077216.1 CDS ECSP_1295 NC_013008.1 1370540 1371154 D hypothetical protein 1370540..1371154 Escherichia coli O157:H7 str. TW14359 8215861 YP_003077217.1 CDS ECSP_1296 NC_013008.1 1371296 1371571 R hypothetical protein complement(1371296..1371571) Escherichia coli O157:H7 str. TW14359 8215862 YP_003077218.1 CDS ECSP_1297 NC_013008.1 1371573 1371968 R IS1 protein InsB complement(1371573..1371968) Escherichia coli O157:H7 str. TW14359 8215863 YP_003077219.1 CDS ECSP_1298 NC_013008.1 1371995 1372270 R IS1 repressor protein InsA complement(1371995..1372270) Escherichia coli O157:H7 str. TW14359 8215864 YP_003077220.1 CDS ECSP_1299 NC_013008.1 1372508 1372966 R hypothetical protein complement(1372508..1372966) Escherichia coli O157:H7 str. TW14359 8215865 YP_003077221.1 CDS ECSP_1300 NC_013008.1 1373424 1373933 D hypothetical protein 1373424..1373933 Escherichia coli O157:H7 str. TW14359 8215866 YP_003077222.1 CDS ECSP_1301 NC_013008.1 1374022 1374645 D hypothetical protein 1374022..1374645 Escherichia coli O157:H7 str. TW14359 8215867 YP_003077223.1 CDS ECSP_1302 NC_013008.1 1374741 1374974 D hypothetical protein 1374741..1374974 Escherichia coli O157:H7 str. TW14359 8215868 YP_003077224.1 CDS ECSP_1303 NC_013008.1 1375027 1375218 R hypothetical protein complement(1375027..1375218) Escherichia coli O157:H7 str. TW14359 8215869 YP_003077225.1 CDS ECSP_1304 NC_013008.1 1375446 1375568 D hypothetical protein 1375446..1375568 Escherichia coli O157:H7 str. TW14359 8215870 YP_003077226.1 CDS ECSP_1305 NC_013008.1 1375812 1376699 R transposase complement(1375812..1376699) Escherichia coli O157:H7 str. TW14359 8215871 YP_003077227.1 CDS ECSP_1306 NC_013008.1 1376699 1377025 R transposase complement(1376699..1377025) Escherichia coli O157:H7 str. TW14359 8215872 YP_003077228.1 CDS ECSP_1307 NC_013008.1 1377188 1378252 D hemolysin activator protein 1377188..1378252 Escherichia coli O157:H7 str. TW14359 8215873 YP_003077229.1 CDS ECSP_1309 NC_013008.1 1381674 1382906 D hypothetical protein 1381674..1382906 Escherichia coli O157:H7 str. TW14359 8215875 YP_003077230.1 CDS ECSP_1310 NC_013008.1 1382891 1383529 D hypothetical protein 1382891..1383529 Escherichia coli O157:H7 str. TW14359 8215876 YP_003077231.1 CDS ECSP_1311 NC_013008.1 1383608 1383877 D hypothetical protein 1383608..1383877 Escherichia coli O157:H7 str. TW14359 8215877 YP_003077232.1 CDS ECSP_1312 NC_013008.1 1383898 1384542 D hypothetical protein 1383898..1384542 Escherichia coli O157:H7 str. TW14359 8215878 YP_003077233.1 CDS ECSP_1313 NC_013008.1 1384590 1384745 D hypothetical protein 1384590..1384745 Escherichia coli O157:H7 str. TW14359 8215879 YP_003077234.1 CDS ECSP_1314 NC_013008.1 1384901 1385200 D transposase 1384901..1385200 Escherichia coli O157:H7 str. TW14359 8215880 YP_003077235.1 CDS ECSP_1315 NC_013008.1 1385240 1385488 R transposase complement(1385240..1385488) Escherichia coli O157:H7 str. TW14359 8215881 YP_003077236.1 CDS ECSP_1316 NC_013008.1 1385542 1385967 D hypothetical protein 1385542..1385967 Escherichia coli O157:H7 str. TW14359 8215882 YP_003077237.1 CDS ECSP_1317 NC_013008.1 1386267 1386449 R hypothetical protein complement(1386267..1386449) Escherichia coli O157:H7 str. TW14359 8215883 YP_003077238.1 CDS ECSP_1318 NC_013008.1 1386779 1387651 D hypothetical protein 1386779..1387651 Escherichia coli O157:H7 str. TW14359 8215884 YP_003077239.1 CDS cah NC_013008.1 1388023 1390872 D calcium-binding autotransporter 1388023..1390872 Escherichia coli O157:H7 str. TW14359 8215885 YP_003077240.1 CDS ECSP_1320 NC_013008.1 1390980 1393367 D hypothetical protein 1390980..1393367 Escherichia coli O157:H7 str. TW14359 8215886 YP_003077241.1 CDS ECSP_1321 NC_013008.1 1393364 1394269 D hypothetical protein 1393364..1394269 Escherichia coli O157:H7 str. TW14359 8215887 YP_003077242.1 CDS ECSP_1322 NC_013008.1 1394266 1395336 D hypothetical protein 1394266..1395336 Escherichia coli O157:H7 str. TW14359 8215888 YP_003077243.1 CDS ECSP_1323 NC_013008.1 1395676 1396494 D hypothetical protein 1395676..1396494 Escherichia coli O157:H7 str. TW14359 8215889 YP_003077244.1 CDS ECSP_1324 NC_013008.1 1396585 1397070 D hypothetical protein 1396585..1397070 Escherichia coli O157:H7 str. TW14359 8215890 YP_003077245.1 CDS ECSP_1325 NC_013008.1 1397086 1397562 D DNA repair protein, RADC family 1397086..1397562 Escherichia coli O157:H7 str. TW14359 8215891 YP_003077246.1 CDS ECSP_1326 NC_013008.1 1397625 1397846 D hypothetical protein 1397625..1397846 Escherichia coli O157:H7 str. TW14359 8215892 YP_003077247.1 CDS ECSP_1327 NC_013008.1 1397846 1397959 D hypothetical protein 1397846..1397959 Escherichia coli O157:H7 str. TW14359 8215893 YP_003077248.1 CDS ECSP_1328 NC_013008.1 1398009 1398383 D structural protein 1398009..1398383 Escherichia coli O157:H7 str. TW14359 8215894 YP_003077249.1 CDS ECSP_1329 NC_013008.1 1398430 1398804 D hypothetical protein 1398430..1398804 Escherichia coli O157:H7 str. TW14359 8215895 YP_003077250.1 CDS ECSP_1330 NC_013008.1 1398801 1399292 D hypothetical protein 1398801..1399292 Escherichia coli O157:H7 str. TW14359 8215896 YP_003077251.1 CDS ECSP_1331 NC_013008.1 1399304 1399501 D hypothetical protein 1399304..1399501 Escherichia coli O157:H7 str. TW14359 8215897 YP_003077252.1 CDS ECSP_1332 NC_013008.1 1399586 1400428 D hypothetical protein 1399586..1400428 Escherichia coli O157:H7 str. TW14359 8215898 YP_003077253.1 CDS ycdW NC_013008.1 1400899 1401837 D 2-ketoacid reductase 1400899..1401837 Escherichia coli O157:H7 str. TW14359 8215900 YP_003077254.1 CDS ycdX NC_013008.1 1401892 1402629 D hydrolase 1401892..1402629 Escherichia coli O157:H7 str. TW14359 8215901 YP_003077255.1 CDS ycdY NC_013008.1 1402653 1403207 D hypothetical protein 1402653..1403207 Escherichia coli O157:H7 str. TW14359 8215902 YP_003077256.1 CDS ycdZ NC_013008.1 1403309 1403800 D inner membrane protein 1403309..1403800 Escherichia coli O157:H7 str. TW14359 8215903 YP_003077257.1 CDS csgG NC_013008.1 1403864 1404697 R curli production assembly/transport component, 2nd curli operon complement(1403864..1404697) Escherichia coli O157:H7 str. TW14359 8215904 YP_003077258.1 CDS csgF NC_013008.1 1404724 1405140 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1404724..1405140) Escherichia coli O157:H7 str. TW14359 8215905 YP_003077259.1 CDS csgE NC_013008.1 1405165 1405554 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1405165..1405554) Escherichia coli O157:H7 str. TW14359 8215906 YP_003077260.1 CDS csgD NC_013008.1 1405559 1406209 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1405559..1406209) Escherichia coli O157:H7 str. TW14359 8215907 YP_003077261.1 CDS ECSP_1342 NC_013008.1 1406621 1406869 R hypothetical protein complement(1406621..1406869) Escherichia coli O157:H7 str. TW14359 8215908 YP_003077262.1 CDS csgB NC_013008.1 1406963 1407418 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1406963..1407418 Escherichia coli O157:H7 str. TW14359 8215909 YP_003077263.1 CDS csgA NC_013008.1 1407459 1407917 D cryptic curlin major subunit 1407459..1407917 Escherichia coli O157:H7 str. TW14359 8215910 YP_003077264.1 CDS csgC NC_013008.1 1407976 1408308 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1407976..1408308 Escherichia coli O157:H7 str. TW14359 8215911 YP_003077265.1 CDS ymdA NC_013008.1 1408429 1408740 D hypothetical protein 1408429..1408740 Escherichia coli O157:H7 str. TW14359 8215912 YP_003077266.1 CDS ymdB NC_013008.1 1408835 1409368 D hypothetical protein 1408835..1409368 Escherichia coli O157:H7 str. TW14359 8215913 YP_003077267.1 CDS ymdC NC_013008.1 1409370 1410791 D hydrolase 1409370..1410791 Escherichia coli O157:H7 str. TW14359 8215914 YP_003077268.1 CDS mdoC NC_013008.1 1410799 1411956 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1410799..1411956) Escherichia coli O157:H7 str. TW14359 8215915 YP_003077269.1 CDS mdoG NC_013008.1 1412349 1413884 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1412349..1413884 Escherichia coli O157:H7 str. TW14359 8215916 YP_003077270.1 CDS mdoH NC_013008.1 1413877 1416420 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1413877..1416420 Escherichia coli O157:H7 str. TW14359 8215917 YP_003077271.1 CDS yceK NC_013008.1 1416593 1416820 D hypothetical protein 1416593..1416820 Escherichia coli O157:H7 str. TW14359 8215918 YP_003077272.1 CDS msyB NC_013008.1 1416821 1417195 R hypothetical protein complement(1416821..1417195) Escherichia coli O157:H7 str. TW14359 8215919 YP_003077273.1 CDS lpxL NC_013008.1 1418676 1419596 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1418676..1419596) Escherichia coli O157:H7 str. TW14359 8215921 YP_003077274.1 CDS yceA NC_013008.1 1419821 1420873 D hypothetical protein 1419821..1420873 Escherichia coli O157:H7 str. TW14359 8215922 YP_003077275.1 CDS yceI NC_013008.1 1420915 1421490 R hypothetical protein complement(1420915..1421490) Escherichia coli O157:H7 str. TW14359 8215923 YP_003077276.1 CDS yceJ NC_013008.1 1421494 1422060 R cytochrome b561 complement(1421494..1422060) Escherichia coli O157:H7 str. TW14359 8215924 YP_003077277.1 CDS yceO NC_013008.1 1422321 1422461 R hypothetical protein complement(1422321..1422461) Escherichia coli O157:H7 str. TW14359 8215925 YP_003077278.1 CDS solA NC_013008.1 1422482 1423600 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1422482..1423600) Escherichia coli O157:H7 str. TW14359 8215926 YP_003077279.1 CDS bssS NC_013008.1 1423715 1423969 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1423715..1423969) Escherichia coli O157:H7 str. TW14359 8215927 YP_003077280.1 CDS dinI NC_013008.1 1424259 1424504 R DNA damage-inducible protein I complement(1424259..1424504) Escherichia coli O157:H7 str. TW14359 8215928 YP_003077281.1 CDS pyrC NC_013008.1 1424578 1425624 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1424578..1425624) Escherichia coli O157:H7 str. TW14359 8215929 YP_003077282.1 CDS yceB NC_013008.1 1425730 1426290 R hypothetical protein complement(1425730..1426290) Escherichia coli O157:H7 str. TW14359 8215930 YP_003077283.1 CDS grxB NC_013008.1 1426424 1427071 R cofactor involved in the reduction of disulfides; glutaredoxin 2 complement(1426424..1427071) Escherichia coli O157:H7 str. TW14359 8215931 YP_003077284.1 CDS mdtH NC_013008.1 1427135 1428343 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1427135..1428343) Escherichia coli O157:H7 str. TW14359 8215932 YP_003077285.1 CDS rimJ NC_013008.1 1428579 1429163 D ribosomal-protein-S5-alanine N-acetyltransferase 1428579..1429163 Escherichia coli O157:H7 str. TW14359 8215933 YP_003077286.1 CDS yceH NC_013008.1 1429174 1429821 D hypothetical protein 1429174..1429821 Escherichia coli O157:H7 str. TW14359 8215934 YP_003077287.1 CDS mviM NC_013008.1 1429823 1430746 D oxidoreductase 1429823..1430746 Escherichia coli O157:H7 str. TW14359 8215935 YP_003077288.1 CDS yceN NC_013008.1 1430856 1432391 D inner membrane protein 1430856..1432391 Escherichia coli O157:H7 str. TW14359 8215936 YP_003077289.1 CDS flgN NC_013008.1 1432431 1432847 R export chaperone for FlgK and FlgL complement(1432431..1432847) Escherichia coli O157:H7 str. TW14359 8215937 YP_003077290.1 CDS flgM NC_013008.1 1432852 1433145 R regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM complement(1432852..1433145) Escherichia coli O157:H7 str. TW14359 8215938 YP_003077291.1 CDS flgA NC_013008.1 1433221 1433880 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1433221..1433880) Escherichia coli O157:H7 str. TW14359 8215939 YP_003077292.1 CDS flgB NC_013008.1 1434035 1434451 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1434035..1434451 Escherichia coli O157:H7 str. TW14359 8215940 YP_003077293.1 CDS flgC NC_013008.1 1434455 1434859 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1434455..1434859 Escherichia coli O157:H7 str. TW14359 8215941 YP_003077294.1 CDS flgD NC_013008.1 1434871 1435566 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1434871..1435566 Escherichia coli O157:H7 str. TW14359 8215942 YP_003077295.1 CDS flgE NC_013008.1 1435591 1436796 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1435591..1436796 Escherichia coli O157:H7 str. TW14359 8215943 YP_003077296.1 CDS flgF NC_013008.1 1436816 1437571 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1436816..1437571 Escherichia coli O157:H7 str. TW14359 8215944 YP_003077297.1 CDS flgG NC_013008.1 1437709 1438491 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1437709..1438491 Escherichia coli O157:H7 str. TW14359 8215945 YP_003077298.1 CDS flgH NC_013008.1 1438544 1439242 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1438544..1439242 Escherichia coli O157:H7 str. TW14359 8215946 YP_003077299.1 CDS flgI NC_013008.1 1439254 1440351 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1439254..1440351 Escherichia coli O157:H7 str. TW14359 8215947 YP_003077300.1 CDS flgJ NC_013008.1 1440351 1441292 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1440351..1441292 Escherichia coli O157:H7 str. TW14359 8215948 YP_003077301.1 CDS flgK NC_013008.1 1441358 1443001 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1441358..1443001 Escherichia coli O157:H7 str. TW14359 8215949 YP_003077302.1 CDS flgL NC_013008.1 1443013 1443966 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1443013..1443966 Escherichia coli O157:H7 str. TW14359 8215950 YP_003077303.1 CDS rne NC_013008.1 1444161 1447346 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1444161..1447346) Escherichia coli O157:H7 str. TW14359 8215951 YP_003077304.1 CDS yceQ NC_013008.1 1447481 1447801 D hypothetical protein 1447481..1447801 Escherichia coli O157:H7 str. TW14359 8215952 YP_003077305.1 CDS rluC NC_013008.1 1447919 1448878 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1447919..1448878 Escherichia coli O157:H7 str. TW14359 8215953 YP_003077306.1 CDS yceF NC_013008.1 1448979 1449563 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1448979..1449563) Escherichia coli O157:H7 str. TW14359 8215954 YP_003077307.1 CDS yceD NC_013008.1 1449762 1450283 D hypothetical protein 1449762..1450283 Escherichia coli O157:H7 str. TW14359 8215955 YP_003077308.1 CDS rpmF NC_013008.1 1450335 1450508 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1450335..1450508 Escherichia coli O157:H7 str. TW14359 8215956 YP_003077309.1 CDS plsX NC_013008.1 1450589 1451659 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1450589..1451659 Escherichia coli O157:H7 str. TW14359 8215957 YP_003077310.1 CDS fabH NC_013008.1 1451727 1452680 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1451727..1452680 Escherichia coli O157:H7 str. TW14359 8215958 YP_003077311.1 CDS fabD NC_013008.1 1452696 1453625 D malonyl CoA-ACP transacylase 1452696..1453625 Escherichia coli O157:H7 str. TW14359 8215959 YP_003077312.1 CDS fabG NC_013008.1 1453638 1454372 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1453638..1454372 Escherichia coli O157:H7 str. TW14359 8215960 YP_003077313.1 CDS acpP NC_013008.1 1454583 1454819 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1454583..1454819 Escherichia coli O157:H7 str. TW14359 8215961 YP_003077314.1 CDS fabF NC_013008.1 1454907 1456148 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1454907..1456148 Escherichia coli O157:H7 str. TW14359 8215962 YP_003077315.1 CDS pabC NC_013008.1 1456268 1457077 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1456268..1457077 Escherichia coli O157:H7 str. TW14359 8215963 YP_003077316.1 CDS yceG NC_013008.1 1457080 1458102 D hypothetical protein 1457080..1458102 Escherichia coli O157:H7 str. TW14359 8215964 YP_003077317.1 CDS tmk NC_013008.1 1458092 1458733 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1458092..1458733 Escherichia coli O157:H7 str. TW14359 8215965 YP_003077318.1 CDS holB NC_013008.1 1458730 1459734 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1458730..1459734 Escherichia coli O157:H7 str. TW14359 8215966 YP_003077319.1 CDS ycfH NC_013008.1 1459745 1460542 D metallodependent hydrolase 1459745..1460542 Escherichia coli O157:H7 str. TW14359 8215967 YP_003077320.1 CDS ptsG NC_013008.1 1460837 1462270 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1460837..1462270 Escherichia coli O157:H7 str. TW14359 8215968 YP_003077321.1 CDS fhuE NC_013008.1 1462330 1464519 R ferric-rhodotorulic acid outer membrane transporter complement(1462330..1464519) Escherichia coli O157:H7 str. TW14359 8215969 YP_003077322.1 CDS ECSP_1404 NC_013008.1 1464552 1464740 R hypothetical protein complement(1464552..1464740) Escherichia coli O157:H7 str. TW14359 8215970 YP_003077323.1 CDS hinT NC_013008.1 1464871 1465230 D purine nucleoside phosphoramidase 1464871..1465230 Escherichia coli O157:H7 str. TW14359 8215971 YP_003077324.1 CDS ycfL NC_013008.1 1465233 1465610 D lipoprotein 1465233..1465610 Escherichia coli O157:H7 str. TW14359 8215972 YP_003077325.1 CDS ycfM NC_013008.1 1465624 1466265 D outer membrane lipoprotein 1465624..1466265 Escherichia coli O157:H7 str. TW14359 8215973 YP_003077326.1 CDS thiK NC_013008.1 1466246 1467070 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1466246..1467070 Escherichia coli O157:H7 str. TW14359 8215974 YP_003077327.1 CDS nagZ NC_013008.1 1467081 1468106 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1467081..1468106 Escherichia coli O157:H7 str. TW14359 8215975 YP_003077328.1 CDS ycfP NC_013008.1 1468129 1468671 D hypothetical protein 1468129..1468671 Escherichia coli O157:H7 str. TW14359 8215976 YP_003077329.1 CDS ndh NC_013008.1 1469071 1470375 D respiratory NADH dehydrogenase 2/cupric reductase 1469071..1470375 Escherichia coli O157:H7 str. TW14359 8215977 YP_003077330.1 CDS ycfJ NC_013008.1 1470602 1471141 D hypothetical protein 1470602..1471141 Escherichia coli O157:H7 str. TW14359 8215978 YP_003077331.1 CDS ycfQ NC_013008.1 1471203 1471835 R DNA-binding transcriptional regulator complement(1471203..1471835) Escherichia coli O157:H7 str. TW14359 8215979 YP_003077332.1 CDS ycfR NC_013008.1 1472076 1472333 D hypothetical protein 1472076..1472333 Escherichia coli O157:H7 str. TW14359 8215980 YP_003077333.1 CDS ycfS NC_013008.1 1472416 1473378 R hypothetical protein complement(1472416..1473378) Escherichia coli O157:H7 str. TW14359 8215981 YP_003077334.1 CDS mfd NC_013008.1 1473522 1476968 R transcription-repair coupling factor complement(1473522..1476968) Escherichia coli O157:H7 str. TW14359 8215982 YP_003077335.1 CDS ycfT NC_013008.1 1477096 1478169 R inner membrane protein complement(1477096..1478169) Escherichia coli O157:H7 str. TW14359 8215983 YP_003077336.1 CDS lolC NC_013008.1 1478431 1479630 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1478431..1479630 Escherichia coli O157:H7 str. TW14359 8215984 YP_003077337.1 CDS lolD NC_013008.1 1479623 1480324 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1479623..1480324 Escherichia coli O157:H7 str. TW14359 8215985 YP_003077338.1 CDS lolE NC_013008.1 1480324 1481568 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1480324..1481568 Escherichia coli O157:H7 str. TW14359 8215986 YP_003077339.1 CDS ycfX NC_013008.1 1481597 1482508 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1481597..1482508 Escherichia coli O157:H7 str. TW14359 8215987 YP_003077340.1 CDS cobB NC_013008.1 1482524 1483345 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1482524..1483345 Escherichia coli O157:H7 str. TW14359 8215988 YP_003077341.1 CDS potD NC_013008.1 1483501 1484547 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1483501..1484547) Escherichia coli O157:H7 str. TW14359 8215989 YP_003077342.1 CDS potC NC_013008.1 1484544 1485338 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1484544..1485338) Escherichia coli O157:H7 str. TW14359 8215990 YP_003077343.1 CDS intN NC_013008.1 1485505 1486623 R integrase for prophage CP-933N complement(1485505..1486623) Escherichia coli O157:H7 str. TW14359 8215991 YP_003077344.1 CDS xisN NC_013008.1 1486592 1486861 R excisionase for prophage CP-933N complement(1486592..1486861) Escherichia coli O157:H7 str. TW14359 8215992 YP_003077345.1 CDS ECSP_1427 NC_013008.1 1486923 1487267 R hypothetical protein complement(1486923..1487267) Escherichia coli O157:H7 str. TW14359 8215993 YP_003077346.1 CDS ECSP_1428 NC_013008.1 1487445 1487960 D hypothetical protein 1487445..1487960 Escherichia coli O157:H7 str. TW14359 8215994 YP_003077347.1 CDS ECSP_1429 NC_013008.1 1488075 1488305 R hypothetical protein complement(1488075..1488305) Escherichia coli O157:H7 str. TW14359 8215995 YP_003077348.1 CDS ECSP_1430 NC_013008.1 1488543 1489019 R hypothetical protein complement(1488543..1489019) Escherichia coli O157:H7 str. TW14359 8215996 YP_003077349.1 CDS ECSP_1431 NC_013008.1 1489144 1489467 D hypothetical protein 1489144..1489467 Escherichia coli O157:H7 str. TW14359 8215997 YP_003077350.1 CDS ECSP_1432 NC_013008.1 1489451 1489876 D hypothetical protein 1489451..1489876 Escherichia coli O157:H7 str. TW14359 8215998 YP_003077351.1 CDS ECSP_1433 NC_013008.1 1489945 1490982 D hypothetical protein 1489945..1490982 Escherichia coli O157:H7 str. TW14359 8215999 YP_003077352.1 CDS ECSP_1434 NC_013008.1 1491014 1491436 D hypothetical protein 1491014..1491436 Escherichia coli O157:H7 str. TW14359 8216000 YP_003077353.1 CDS ECSP_1435 NC_013008.1 1491470 1492186 D hypothetical protein 1491470..1492186 Escherichia coli O157:H7 str. TW14359 8216001 YP_003077354.1 CDS ECSP_1436 NC_013008.1 1492183 1492500 D hypothetical protein 1492183..1492500 Escherichia coli O157:H7 str. TW14359 8216002 YP_003077355.1 CDS ECSP_1437 NC_013008.1 1492497 1492799 D hypothetical protein 1492497..1492799 Escherichia coli O157:H7 str. TW14359 8216003 YP_003077356.1 CDS ECSP_1438 NC_013008.1 1492789 1493106 D hypothetical protein 1492789..1493106 Escherichia coli O157:H7 str. TW14359 8216004 YP_003077357.1 CDS ECSP_1439 NC_013008.1 1493108 1493377 D hypothetical protein 1493108..1493377 Escherichia coli O157:H7 str. TW14359 8216005 YP_003077358.1 CDS ECSP_1440 NC_013008.1 1493364 1493801 D hypothetical protein 1493364..1493801 Escherichia coli O157:H7 str. TW14359 8216006 YP_003077359.1 CDS ECSP_1441 NC_013008.1 1493997 1494584 D hypothetical protein 1493997..1494584 Escherichia coli O157:H7 str. TW14359 8216007 YP_003077360.1 CDS ECSP_1442 NC_013008.1 1494993 1495205 D Gef-like protein encoded by prophage CP-933N 1494993..1495205 Escherichia coli O157:H7 str. TW14359 8216008 YP_003077361.1 CDS ECSP_1443 NC_013008.1 1495242 1495337 D hypothetical protein 1495242..1495337 Escherichia coli O157:H7 str. TW14359 8216009 YP_003077362.1 CDS ECSP_1444 NC_013008.1 1495391 1495570 R hypothetical protein complement(1495391..1495570) Escherichia coli O157:H7 str. TW14359 8216010 YP_003077363.1 CDS ECSP_1445 NC_013008.1 1495653 1496702 D hypothetical protein 1495653..1496702 Escherichia coli O157:H7 str. TW14359 8216011 YP_003077364.1 CDS ECSP_1446 NC_013008.1 1496715 1496972 D hypothetical protein 1496715..1496972 Escherichia coli O157:H7 str. TW14359 8216012 YP_003077365.1 CDS ECSP_1447 NC_013008.1 1496953 1498245 D hypothetical protein 1496953..1498245 Escherichia coli O157:H7 str. TW14359 8216013 YP_003077366.1 CDS ECSP_1448 NC_013008.1 1498393 1498575 D hypothetical protein 1498393..1498575 Escherichia coli O157:H7 str. TW14359 8216014 YP_003077367.1 CDS ECSP_1449 NC_013008.1 1498613 1498882 D hypothetical protein 1498613..1498882 Escherichia coli O157:H7 str. TW14359 8216015 YP_003077368.1 CDS ECSP_1450 NC_013008.1 1498958 1499173 D hypothetical protein 1498958..1499173 Escherichia coli O157:H7 str. TW14359 8216016 YP_003077369.1 CDS ECSP_1451 NC_013008.1 1499178 1499522 D hypothetical protein 1499178..1499522 Escherichia coli O157:H7 str. TW14359 8216017 YP_003077370.1 CDS ECSP_1452 NC_013008.1 1499573 1500106 D endolysin of prophage CP-933N 1499573..1500106 Escherichia coli O157:H7 str. TW14359 8216018 YP_003077371.1 CDS ECSP_1453 NC_013008.1 1500377 1500946 D antirepressor protein 1500377..1500946 Escherichia coli O157:H7 str. TW14359 8216019 YP_003077372.1 CDS ECSP_1454 NC_013008.1 1501100 1501567 D bacteriophage lysis protein 1501100..1501567 Escherichia coli O157:H7 str. TW14359 8216020 YP_003077373.1 CDS ECSP_1455 NC_013008.1 1501591 1501815 D hypothetical protein 1501591..1501815 Escherichia coli O157:H7 str. TW14359 8216021 YP_003077374.1 CDS ECSP_1456 NC_013008.1 1501963 1502085 D hypothetical protein 1501963..1502085 Escherichia coli O157:H7 str. TW14359 8216022 YP_003077375.1 CDS ECSP_1457 NC_013008.1 1502172 1502312 D hypothetical protein 1502172..1502312 Escherichia coli O157:H7 str. TW14359 8216023 YP_003077376.1 CDS ECSP_1458 NC_013008.1 1502669 1503034 D HNH endonuclease 1502669..1503034 Escherichia coli O157:H7 str. TW14359 8216024 YP_003077377.1 CDS ECSP_1459 NC_013008.1 1503324 1503887 D hypothetical protein 1503324..1503887 Escherichia coli O157:H7 str. TW14359 8216025 YP_003077378.1 CDS ECSP_1460 NC_013008.1 1503884 1505545 D phage terminase, large subunit 1503884..1505545 Escherichia coli O157:H7 str. TW14359 8216026 YP_003077379.1 CDS ECSP_1461 NC_013008.1 1505609 1507546 D prohead protease 1505609..1507546 Escherichia coli O157:H7 str. TW14359 8216027 YP_003077380.1 CDS ECSP_1462 NC_013008.1 1507758 1510259 D portal protein 1507758..1510259 Escherichia coli O157:H7 str. TW14359 8216028 YP_003077381.1 CDS ECSP_1463 NC_013008.1 1510339 1510665 D hypothetical protein 1510339..1510665 Escherichia coli O157:H7 str. TW14359 8216029 YP_003077382.1 CDS ECSP_1464 NC_013008.1 1510675 1511025 D head-tail adaptor 1510675..1511025 Escherichia coli O157:H7 str. TW14359 8216030 YP_003077383.1 CDS ECSP_1465 NC_013008.1 1511022 1511468 D hypothetical protein 1511022..1511468 Escherichia coli O157:H7 str. TW14359 8216031 YP_003077384.1 CDS ECSP_1466 NC_013008.1 1511465 1511809 D hypothetical protein 1511465..1511809 Escherichia coli O157:H7 str. TW14359 8216032 YP_003077385.1 CDS ECSP_1467 NC_013008.1 1511875 1512591 D hypothetical protein 1511875..1512591 Escherichia coli O157:H7 str. TW14359 8216033 YP_003077386.1 CDS ECSP_1468 NC_013008.1 1512558 1512980 D tail assembly chaperone encoded by prophage CP-933N 1512558..1512980 Escherichia coli O157:H7 str. TW14359 8216034 YP_003077387.1 CDS ECSP_1469 NC_013008.1 1513082 1513285 D hypothetical protein 1513082..1513285 Escherichia coli O157:H7 str. TW14359 8216035 YP_003077388.1 CDS ECSP_1470 NC_013008.1 1513338 1516580 D tail length tape measure protein 1513338..1516580 Escherichia coli O157:H7 str. TW14359 8216036 YP_003077389.1 CDS ECSP_1471 NC_013008.1 1516573 1516914 D minor tail protein 1516573..1516914 Escherichia coli O157:H7 str. TW14359 8216037 YP_003077390.1 CDS ECSP_1472 NC_013008.1 1516914 1517612 D minor tail protein 1516914..1517612 Escherichia coli O157:H7 str. TW14359 8216038 YP_003077391.1 CDS ECSP_1473 NC_013008.1 1517629 1517883 R hypothetical protein complement(1517629..1517883) Escherichia coli O157:H7 str. TW14359 8216039 YP_003077392.1 CDS ECSP_1474 NC_013008.1 1517993 1518103 D hypothetical protein 1517993..1518103 Escherichia coli O157:H7 str. TW14359 8216040 YP_003077393.1 CDS ECSP_1475 NC_013008.1 1518406 1519284 D antirepressor protein encoded by prophage CP-933N 1518406..1519284 Escherichia coli O157:H7 str. TW14359 8216041 YP_003077394.1 CDS ECSP_1476 NC_013008.1 1519338 1520075 D encoded by prophage CP-933N; tail component K-like protein 1519338..1520075 Escherichia coli O157:H7 str. TW14359 8216042 YP_003077395.1 CDS ECSP_1477 NC_013008.1 1520072 1520257 D hypothetical protein 1520072..1520257 Escherichia coli O157:H7 str. TW14359 8216043 YP_003077396.1 CDS espX7 NC_013008.1 1520778 1522727 D non-LEE-encoded type III effector 1520778..1522727 Escherichia coli O157:H7 str. TW14359 8216044 YP_003077397.1 CDS espN NC_013008.1 1523906 1526719 D non-LEE-encoded type III effector 1523906..1526719 Escherichia coli O157:H7 str. TW14359 8216045 YP_003077398.1 CDS ECSP_1480 NC_013008.1 1527262 1528167 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(1527262..1528167) Escherichia coli O157:H7 str. TW14359 8216046 YP_003077399.1 CDS ECSP_1482 NC_013008.1 1528447 1528800 D IS encoded protein 1528447..1528800 Escherichia coli O157:H7 str. TW14359 8216048 YP_003077400.1 CDS ECSP_1483 NC_013008.1 1529028 1529303 R non-LEE-encoded type III effector complement(1529028..1529303) Escherichia coli O157:H7 str. TW14359 8216049 YP_003077401.1 CDS espK NC_013008.1 1529364 1530725 R non-LEE-encoded type III effector complement(1529364..1530725) Escherichia coli O157:H7 str. TW14359 8216050 YP_003077402.1 CDS potB NC_013008.1 1531089 1531922 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1531089..1531922) Escherichia coli O157:H7 str. TW14359 8216051 YP_003077403.1 CDS potA NC_013008.1 1531936 1533072 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein complement(1531936..1533072) Escherichia coli O157:H7 str. TW14359 8216052 YP_003077404.1 CDS pepT NC_013008.1 1533322 1534548 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1533322..1534548 Escherichia coli O157:H7 str. TW14359 8216053 YP_003077405.1 CDS ycfD NC_013008.1 1534597 1535718 R hypothetical protein complement(1534597..1535718) Escherichia coli O157:H7 str. TW14359 8216054 YP_003077406.1 CDS ECSP_1489 NC_013008.1 1535798 1535962 R hypothetical protein complement(1535798..1535962) Escherichia coli O157:H7 str. TW14359 8216055 YP_003077407.1 CDS ECSP_1490 NC_013008.1 1535967 1537196 D integrase of prophage CP-933C 1535967..1537196 Escherichia coli O157:H7 str. TW14359 8216056 YP_003077408.1 CDS ECSP_1491 NC_013008.1 1537561 1537749 D DNA binding protein 1537561..1537749 Escherichia coli O157:H7 str. TW14359 8216057 YP_003077409.1 CDS ECSP_1492 NC_013008.1 1537807 1538751 D hypothetical protein 1537807..1538751 Escherichia coli O157:H7 str. TW14359 8216058 YP_003077410.1 CDS ECSP_1493 NC_013008.1 1538744 1538956 D hypothetical protein 1538744..1538956 Escherichia coli O157:H7 str. TW14359 8216059 YP_003077411.1 CDS ECSP_1494 NC_013008.1 1538946 1539410 D hypothetical protein 1538946..1539410 Escherichia coli O157:H7 str. TW14359 8216060 YP_003077412.1 CDS ECSP_1495 NC_013008.1 1539403 1539636 D hypothetical protein 1539403..1539636 Escherichia coli O157:H7 str. TW14359 8216061 YP_003077413.1 CDS ECSP_1496 NC_013008.1 1539642 1539941 D hypothetical protein 1539642..1539941 Escherichia coli O157:H7 str. TW14359 8216062 YP_003077414.1 CDS ECSP_1497 NC_013008.1 1539938 1541338 D hypothetical protein 1539938..1541338 Escherichia coli O157:H7 str. TW14359 8216063 YP_003077415.1 CDS ECSP_1498 NC_013008.1 1541539 1541790 D hypothetical protein 1541539..1541790 Escherichia coli O157:H7 str. TW14359 8216064 YP_003077416.1 CDS ECSP_1499 NC_013008.1 1541787 1542197 D single stranded DNA-binding protein of prophage CP-933C 1541787..1542197 Escherichia coli O157:H7 str. TW14359 8216065 YP_003077417.1 CDS ECSP_1500 NC_013008.1 1542208 1542480 D transcriptional activator 1542208..1542480 Escherichia coli O157:H7 str. TW14359 8216066 YP_003077418.1 CDS ECSP_1501 NC_013008.1 1542607 1542831 D hypothetical protein 1542607..1542831 Escherichia coli O157:H7 str. TW14359 8216067 YP_003077419.1 CDS ECSP_1502 NC_013008.1 1543083 1543289 D hypothetical protein 1543083..1543289 Escherichia coli O157:H7 str. TW14359 8216068 YP_003077420.1 CDS ECSP_1503 NC_013008.1 1543289 1544344 D capsid protein of prophage 1543289..1544344 Escherichia coli O157:H7 str. TW14359 8216069 YP_003077421.1 CDS ECSP_1504 NC_013008.1 1544357 1544692 D hypothetical protein 1544357..1544692 Escherichia coli O157:H7 str. TW14359 8216070 YP_003077422.1 CDS ECSP_1505 NC_013008.1 1544705 1545118 D hypothetical protein 1544705..1545118 Escherichia coli O157:H7 str. TW14359 8216071 YP_003077423.1 CDS ECSP_1506 NC_013008.1 1545339 1545866 D DNA packaging protein 1545339..1545866 Escherichia coli O157:H7 str. TW14359 8216072 YP_003077424.1 CDS ECSP_1507 NC_013008.1 1546122 1546403 D hypothetical protein 1546122..1546403 Escherichia coli O157:H7 str. TW14359 8216073 YP_003077425.1 CDS ECSP_1508 NC_013008.1 1546584 1546727 R hypothetical protein complement(1546584..1546727) Escherichia coli O157:H7 str. TW14359 8216074 YP_003077426.1 CDS phoQ NC_013008.1 1547004 1548464 R sensor protein PhoQ complement(1547004..1548464) Escherichia coli O157:H7 str. TW14359 8216075 YP_003077427.1 CDS phoP NC_013008.1 1548464 1549135 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1548464..1549135) Escherichia coli O157:H7 str. TW14359 8216076 YP_003077428.1 CDS purB NC_013008.1 1549304 1550674 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1549304..1550674) Escherichia coli O157:H7 str. TW14359 8216077 YP_003077429.1 CDS hflD NC_013008.1 1550678 1551319 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1550678..1551319) Escherichia coli O157:H7 str. TW14359 8216078 YP_003077430.1 CDS mnmA NC_013008.1 1551355 1552461 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1551355..1552461) Escherichia coli O157:H7 str. TW14359 8216079 YP_003077431.1 CDS nudJ NC_013008.1 1552515 1552976 R thiamin pyrophosphate (TPP) hydrolase complement(1552515..1552976) Escherichia coli O157:H7 str. TW14359 8216080 YP_003077432.1 CDS rluE NC_013008.1 1552986 1553639 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1552986..1553639) Escherichia coli O157:H7 str. TW14359 8216081 YP_003077433.1 CDS icd NC_013008.1 1553811 1555061 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1553811..1555061 Escherichia coli O157:H7 str. TW14359 8216082 YP_003077434.1 CDS ECSP_1517 NC_013008.1 1555175 1556317 R integrase of prophage CP-933X complement(1555175..1556317) Escherichia coli O157:H7 str. TW14359 8216083 YP_003077435.1 CDS ECSP_1518 NC_013008.1 1556307 1556543 R integrase of prophage CP-933X complement(1556307..1556543) Escherichia coli O157:H7 str. TW14359 8216084 YP_003077436.1 CDS ECSP_1519 NC_013008.1 1556647 1557471 D replication protein O of prophage CP-933X 1556647..1557471 Escherichia coli O157:H7 str. TW14359 8216085 YP_003077437.1 CDS ECSP_1520 NC_013008.1 1557468 1558169 D replication protein P of prophage CP-933X 1557468..1558169 Escherichia coli O157:H7 str. TW14359 8216086 YP_003077438.1 CDS ECSP_1521 NC_013008.1 1558166 1558468 D ren protein 1558166..1558468 Escherichia coli O157:H7 str. TW14359 8216087 YP_003077439.1 CDS emrE NC_013008.1 1558536 1558868 D member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 1558536..1558868 Escherichia coli O157:H7 str. TW14359 8216088 YP_003077440.1 CDS ECSP_1523 NC_013008.1 1559113 1560240 D hypothetical protein 1559113..1560240 Escherichia coli O157:H7 str. TW14359 8216089 YP_003077441.1 CDS ECSP_1524 NC_013008.1 1561137 1561592 D DLP12 prophage; hypothetical protein 1561137..1561592 Escherichia coli O157:H7 str. TW14359 8216090 YP_003077442.1 CDS ECSP_1525 NC_013008.1 1561755 1562045 D hypothetical protein 1561755..1562045 Escherichia coli O157:H7 str. TW14359 8216091 YP_003077443.1 CDS rus NC_013008.1 1562042 1562404 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1562042..1562404 Escherichia coli O157:H7 str. TW14359 8216092 YP_003077444.1 CDS ECSP_1527 NC_013008.1 1562538 1563227 D antiterminator Q of prophage CP-933X 1562538..1563227 Escherichia coli O157:H7 str. TW14359 8216093 YP_003077445.1 CDS ECSP_1528 NC_013008.1 1563549 1563854 D holin protein of prophage CP-933X 1563549..1563854 Escherichia coli O157:H7 str. TW14359 8216094 YP_003077446.1 CDS ECSP_1529 NC_013008.1 1563841 1564317 D endolysin of prophage CP-933X 1563841..1564317 Escherichia coli O157:H7 str. TW14359 8216095 YP_003077447.1 CDS ECSP_1530 NC_013008.1 1564458 1564775 D endopeptidase of prophage CP-933X 1564458..1564775 Escherichia coli O157:H7 str. TW14359 8216096 YP_003077448.1 CDS ECSP_1531 NC_013008.1 1564807 1565100 R Bor protein of prophage CP-933X complement(1564807..1565100) Escherichia coli O157:H7 str. TW14359 8216097 YP_003077449.1 CDS ECSP_1532 NC_013008.1 1565392 1565802 R envelope protein of prophage CP-933X complement(1565392..1565802) Escherichia coli O157:H7 str. TW14359 8216098 YP_003077450.1 CDS ECSP_1533 NC_013008.1 1566088 1566294 D hypothetical protein 1566088..1566294 Escherichia coli O157:H7 str. TW14359 8216099 YP_003077451.1 CDS ECSP_1534 NC_013008.1 1566459 1566653 R hypothetical protein complement(1566459..1566653) Escherichia coli O157:H7 str. TW14359 8216100 YP_003077452.1 CDS ECSP_1535 NC_013008.1 1567042 1567587 D DNA packaging protein of prophage CP-933X 1567042..1567587 Escherichia coli O157:H7 str. TW14359 8216101 YP_003077453.1 CDS ECSP_1536 NC_013008.1 1567562 1569487 D DNA packaging protein of prophage CP-933X 1567562..1569487 Escherichia coli O157:H7 str. TW14359 8216102 YP_003077454.1 CDS ECSP_1537 NC_013008.1 1569535 1569690 D head-tail joining protein of prophage CP-933X 1569535..1569690 Escherichia coli O157:H7 str. TW14359 8216103 YP_003077455.1 CDS ECSP_1538 NC_013008.1 1569687 1571288 D capsid structural protein of prophage CP-933X 1569687..1571288 Escherichia coli O157:H7 str. TW14359 8216104 YP_003077456.1 CDS ECSP_1539 NC_013008.1 1571269 1572588 D capsid protein of prophage CP-933X 1571269..1572588 Escherichia coli O157:H7 str. TW14359 8216105 YP_003077457.1 CDS ECSP_1540 NC_013008.1 1572986 1574011 D capsid protein of prophage CP-933X 1572986..1574011 Escherichia coli O157:H7 str. TW14359 8216106 YP_003077458.1 CDS ECSP_1541 NC_013008.1 1574014 1574451 D DNA packaging protein of prophage CP-933X 1574014..1574451 Escherichia coli O157:H7 str. TW14359 8216107 YP_003077459.1 CDS ECSP_1542 NC_013008.1 1574463 1574816 D head-tail joining protein of prophage CP-933X 1574463..1574816 Escherichia coli O157:H7 str. TW14359 8216108 YP_003077460.1 CDS ECSP_1543 NC_013008.1 1575161 1575406 D tail component of prophage CP-933X 1575161..1575406 Escherichia coli O157:H7 str. TW14359 8216109 YP_003077461.1 CDS ECSP_1544 NC_013008.1 1575403 1575798 D tail component of prophage CP-933X 1575403..1575798 Escherichia coli O157:H7 str. TW14359 8216110 YP_003077462.1 CDS ECSP_1545 NC_013008.1 1575806 1576546 D tail component of prophage CP-933X 1575806..1576546 Escherichia coli O157:H7 str. TW14359 8216111 YP_003077463.1 CDS ECSP_1546 NC_013008.1 1576562 1576984 D tail component of prophage CP-933X 1576562..1576984 Escherichia coli O157:H7 str. TW14359 8216112 YP_003077464.1 CDS ECSP_1547 NC_013008.1 1576966 1577400 D tail component of prophage CP-933X 1576966..1577400 Escherichia coli O157:H7 str. TW14359 8216113 YP_003077465.1 CDS ECSP_1548 NC_013008.1 1577393 1579942 D tail component of prophage CP-933X 1577393..1579942 Escherichia coli O157:H7 str. TW14359 8216114 YP_003077466.1 CDS ECSP_1549 NC_013008.1 1579939 1580268 D minor tail protein 1579939..1580268 Escherichia coli O157:H7 str. TW14359 8216115 YP_003077467.1 CDS ECSP_1550 NC_013008.1 1580268 1580966 D phage minor tail protein L 1580268..1580966 Escherichia coli O157:H7 str. TW14359 8216116 YP_003077468.1 CDS ECSP_1551 NC_013008.1 1580972 1581715 D tail assembly protein 1580972..1581715 Escherichia coli O157:H7 str. TW14359 8216117 YP_003077469.1 CDS ECSP_1552 NC_013008.1 1581712 1582284 D tail assembly protein I 1581712..1582284 Escherichia coli O157:H7 str. TW14359 8216118 YP_003077470.1 CDS ECSP_1553 NC_013008.1 1582345 1585743 D host specificity protein J 1582345..1585743 Escherichia coli O157:H7 str. TW14359 8216119 YP_003077471.1 CDS ECSP_1554 NC_013008.1 1585810 1586409 D Ail/Lom family protein 1585810..1586409 Escherichia coli O157:H7 str. TW14359 8216120 YP_003077472.1 CDS ECSP_1555 NC_013008.1 1586474 1589389 D membrane protein of prophage CP-933X 1586474..1589389 Escherichia coli O157:H7 str. TW14359 8216121 YP_003077473.1 CDS ECSP_1556 NC_013008.1 1589389 1589970 D tail fiber protein of prophage CP-933X 1589389..1589970 Escherichia coli O157:H7 str. TW14359 8216122 YP_003077474.1 CDS ECSP_1557 NC_013008.1 1590090 1590980 R hypothetical protein complement(1590090..1590980) Escherichia coli O157:H7 str. TW14359 8216123 YP_003077475.1 CDS ECSP_1558 NC_013008.1 1590999 1591505 R hypothetical protein complement(1590999..1591505) Escherichia coli O157:H7 str. TW14359 8216124 YP_003077476.1 CDS ECSP_1559 NC_013008.1 1591542 1592042 R hypothetical protein complement(1591542..1592042) Escherichia coli O157:H7 str. TW14359 8216125 YP_003077477.1 CDS ECSP_1560 NC_013008.1 1592121 1592303 R hypothetical protein complement(1592121..1592303) Escherichia coli O157:H7 str. TW14359 8216126 YP_003077478.1 CDS ECSP_1561 NC_013008.1 1592801 1593457 R hypothetical protein complement(1592801..1593457) Escherichia coli O157:H7 str. TW14359 8216127 YP_003077479.1 CDS ECSP_1562 NC_013008.1 1593526 1593774 D hypothetical protein 1593526..1593774 Escherichia coli O157:H7 str. TW14359 8216128 YP_003077480.1 CDS ECSP_1563 NC_013008.1 1593829 1594230 D hypothetical protein 1593829..1594230 Escherichia coli O157:H7 str. TW14359 8216129 YP_003077481.1 CDS ECSP_1564 NC_013008.1 1594227 1594574 D transposase 1594227..1594574 Escherichia coli O157:H7 str. TW14359 8216130 YP_003077482.1 CDS ECSP_1565 NC_013008.1 1594624 1596162 D transposase 1594624..1596162 Escherichia coli O157:H7 str. TW14359 8216131 YP_003077483.1 CDS ECSP_1566 NC_013008.1 1596465 1597949 R protease encoded within prophage CP-933X complement(1596465..1597949) Escherichia coli O157:H7 str. TW14359 8216132 YP_003077484.1 CDS ompT NC_013008.1 1598136 1599089 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(1598136..1599089) Escherichia coli O157:H7 str. TW14359 8216133 YP_003077485.1 CDS ECSP_1568 NC_013008.1 1599224 1599352 D hypothetical protein 1599224..1599352 Escherichia coli O157:H7 str. TW14359 8216134 YP_003077486.1 CDS ECSP_1569 NC_013008.1 1599570 1600172 D hypothetical protein 1599570..1600172 Escherichia coli O157:H7 str. TW14359 8216135 YP_003077487.1 CDS ECSP_1570 NC_013008.1 1600827 1601039 D hypothetical protein 1600827..1601039 Escherichia coli O157:H7 str. TW14359 8216136 YP_003077488.1 CDS minE NC_013008.1 1601411 1601677 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1601411..1601677) Escherichia coli O157:H7 str. TW14359 8216137 YP_003077489.1 CDS minD NC_013008.1 1601681 1602493 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1601681..1602493) Escherichia coli O157:H7 str. TW14359 8216138 YP_003077490.1 CDS minC NC_013008.1 1602517 1603212 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1602517..1603212) Escherichia coli O157:H7 str. TW14359 8216139 YP_003077491.1 CDS ycgJ NC_013008.1 1603732 1604100 D hypothetical protein 1603732..1604100 Escherichia coli O157:H7 str. TW14359 8216140 YP_003077492.1 CDS ycgK NC_013008.1 1604203 1604604 R hypothetical protein complement(1604203..1604604) Escherichia coli O157:H7 str. TW14359 8216141 YP_003077493.1 CDS ycgL NC_013008.1 1604812 1605138 D hypothetical protein 1604812..1605138 Escherichia coli O157:H7 str. TW14359 8216142 YP_003077494.1 CDS ycgM NC_013008.1 1605210 1605869 D hypothetical protein 1605210..1605869 Escherichia coli O157:H7 str. TW14359 8216143 YP_003077495.1 CDS ycgN NC_013008.1 1605946 1606407 D hypothetical protein 1605946..1606407 Escherichia coli O157:H7 str. TW14359 8216144 YP_003077496.1 CDS hlyE NC_013008.1 1606614 1607525 R Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E complement(1606614..1607525) Escherichia coli O157:H7 str. TW14359 8216145 YP_003077497.1 CDS umuD NC_013008.1 1607898 1608317 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1607898..1608317 Escherichia coli O157:H7 str. TW14359 8216146 YP_003077498.1 CDS umuC NC_013008.1 1608317 1609585 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1608317..1609585 Escherichia coli O157:H7 str. TW14359 8216147 YP_003077499.1 CDS dsbB NC_013008.1 1609631 1610161 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1609631..1610161) Escherichia coli O157:H7 str. TW14359 8216148 YP_003077500.1 CDS nhaB NC_013008.1 1610307 1611848 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1610307..1611848) Escherichia coli O157:H7 str. TW14359 8216149 YP_003077501.1 CDS fadR NC_013008.1 1612070 1612789 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1612070..1612789 Escherichia coli O157:H7 str. TW14359 8216150 YP_003077502.1 CDS ycgB NC_013008.1 1612841 1614373 R SpoVR family protein complement(1612841..1614373) Escherichia coli O157:H7 str. TW14359 8216151 YP_003077503.1 CDS dadA NC_013008.1 1614736 1616034 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1614736..1616034 Escherichia coli O157:H7 str. TW14359 8216152 YP_003077504.1 CDS dadX NC_013008.1 1616044 1617114 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1616044..1617114 Escherichia coli O157:H7 str. TW14359 8216153 YP_003077505.1 CDS cvrA NC_013008.1 1617503 1619239 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1617503..1619239) Escherichia coli O157:H7 str. TW14359 8216154 YP_003077506.1 CDS ldcA NC_013008.1 1619335 1620249 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1619335..1620249) Escherichia coli O157:H7 str. TW14359 8216155 YP_003077507.1 CDS emtA NC_013008.1 1620349 1620960 D lytic murein endotransglycosylase E 1620349..1620960 Escherichia coli O157:H7 str. TW14359 8216156 YP_003077508.1 CDS ECSP_1591 NC_013008.1 1621069 1622229 R outer membrane autotransporter/adhesion protein complement(1621069..1622229) Escherichia coli O157:H7 str. TW14359 8216157 YP_003077509.1 CDS ECSP_1592 NC_013008.1 1622574 1622777 D hypothetical protein 1622574..1622777 Escherichia coli O157:H7 str. TW14359 8216158 YP_003077510.1 CDS ychF NC_013008.1 1623073 1624164 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1623073..1624164) Escherichia coli O157:H7 str. TW14359 8216159 YP_003077511.1 CDS pth NC_013008.1 1624281 1624865 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1624281..1624865) Escherichia coli O157:H7 str. TW14359 8216160 YP_003077512.1 CDS ychH NC_013008.1 1625143 1625421 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1625143..1625421 Escherichia coli O157:H7 str. TW14359 8216161 YP_003077513.1 CDS ychM NC_013008.1 1625476 1627155 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1625476..1627155) Escherichia coli O157:H7 str. TW14359 8216162 YP_003077514.1 CDS prsA NC_013008.1 1627280 1628227 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1627280..1628227) Escherichia coli O157:H7 str. TW14359 8216163 YP_003077515.1 CDS ipk NC_013008.1 1628378 1629229 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1628378..1629229) Escherichia coli O157:H7 str. TW14359 8216164 YP_003077516.1 CDS lolB NC_013008.1 1629229 1629852 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1629229..1629852) Escherichia coli O157:H7 str. TW14359 8216165 YP_003077517.1 CDS hemA NC_013008.1 1630066 1631322 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1630066..1631322 Escherichia coli O157:H7 str. TW14359 8216166 YP_003077518.1 CDS prfA NC_013008.1 1631364 1632446 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1631364..1632446 Escherichia coli O157:H7 str. TW14359 8216167 YP_003077519.1 CDS prmC NC_013008.1 1632446 1633279 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1632446..1633279 Escherichia coli O157:H7 str. TW14359 8216168 YP_003077520.1 CDS ychQ NC_013008.1 1633276 1633668 D transcriptional regulator 1633276..1633668 Escherichia coli O157:H7 str. TW14359 8216169 YP_003077521.1 CDS ychA NC_013008.1 1633672 1634481 D transcriptional regulator 1633672..1634481 Escherichia coli O157:H7 str. TW14359 8216170 YP_003077522.1 CDS kdsA NC_013008.1 1634517 1635371 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1634517..1635371 Escherichia coli O157:H7 str. TW14359 8216171 YP_003077523.1 CDS ldrA NC_013008.1 1635519 1635626 R toxic polypeptide, small complement(1635519..1635626) Escherichia coli O157:H7 str. TW14359 8216172 YP_003077524.1 CDS ldrB NC_013008.1 1636055 1636162 R toxic polypeptide, small complement(1636055..1636162) Escherichia coli O157:H7 str. TW14359 8216173 YP_003077525.1 CDS chaA NC_013008.1 1636561 1637661 R calcium/sodium:proton antiporter complement(1636561..1637661) Escherichia coli O157:H7 str. TW14359 8216174 YP_003077526.1 CDS chaB NC_013008.1 1637931 1638161 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1637931..1638161 Escherichia coli O157:H7 str. TW14359 8216175 YP_003077527.1 CDS chaC NC_013008.1 1638322 1639017 D regulatory protein for cation transport 1638322..1639017 Escherichia coli O157:H7 str. TW14359 8216176 YP_003077528.1 CDS ychN NC_013008.1 1639061 1639414 R hypothetical protein complement(1639061..1639414) Escherichia coli O157:H7 str. TW14359 8216177 YP_003077529.1 CDS ychP NC_013008.1 1639600 1640994 D hypothetical protein 1639600..1640994 Escherichia coli O157:H7 str. TW14359 8216178 YP_003077530.1 CDS narL NC_013008.1 1640995 1641645 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1640995..1641645) Escherichia coli O157:H7 str. TW14359 8216179 YP_003077531.1 CDS narX NC_013008.1 1641638 1643434 R nitrate/nitrite sensor protein NarX complement(1641638..1643434) Escherichia coli O157:H7 str. TW14359 8216180 YP_003077532.1 CDS ECSP_1615 NC_013008.1 1643460 1643678 D hypothetical protein 1643460..1643678 Escherichia coli O157:H7 str. TW14359 8216181 YP_003077533.1 CDS narK NC_013008.1 1643773 1645164 D nitrate/nitrite transporter 1643773..1645164 Escherichia coli O157:H7 str. TW14359 8216182 YP_003077534.1 CDS narG NC_013008.1 1645557 1649300 D nitrate reductase 1 subunit alpha 1645557..1649300 Escherichia coli O157:H7 str. TW14359 8216183 YP_003077535.1 CDS narH NC_013008.1 1649297 1650835 D nitrate reductase 1, beta (Fe-S) subunit 1649297..1650835 Escherichia coli O157:H7 str. TW14359 8216184 YP_003077536.1 CDS narJ NC_013008.1 1650832 1651542 D nitrate reductase 1 minormolybdenum-cofactor-assembly chaperone 1650832..1651542 Escherichia coli O157:H7 str. TW14359 8216185 YP_003077537.1 CDS narI NC_013008.1 1651542 1652219 D nitrate reductase 1, gamma (cytochrome b(NR)) subunit 1651542..1652219 Escherichia coli O157:H7 str. TW14359 8216186 YP_003077538.1 CDS ECSP_1621 NC_013008.1 1652402 1652677 D hypothetical protein 1652402..1652677 Escherichia coli O157:H7 str. TW14359 8216187 YP_003077539.1 CDS purU NC_013008.1 1653297 1654139 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1653297..1654139) Escherichia coli O157:H7 str. TW14359 8216190 YP_003077540.1 CDS ychJ NC_013008.1 1654189 1654647 R hypothetical protein complement(1654189..1654647) Escherichia coli O157:H7 str. TW14359 8216191 YP_003077541.1 CDS rssA NC_013008.1 1654760 1655665 D hypothetical protein 1654760..1655665 Escherichia coli O157:H7 str. TW14359 8216192 YP_003077542.1 CDS rssB NC_013008.1 1655757 1656770 D response regulator of RpoS 1655757..1656770 Escherichia coli O157:H7 str. TW14359 8216193 YP_003077543.1 CDS galU NC_013008.1 1656972 1657880 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1656972..1657880 Escherichia coli O157:H7 str. TW14359 8216194 YP_003077544.1 CDS hns NC_013008.1 1658024 1658437 R global DNA-binding transcriptional dual regulator H-NS complement(1658024..1658437) Escherichia coli O157:H7 str. TW14359 8216195 YP_003077545.1 CDS tdk NC_013008.1 1659041 1659658 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1659041..1659658 Escherichia coli O157:H7 str. TW14359 8216196 YP_003077546.1 CDS adhE NC_013008.1 1659959 1662634 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1659959..1662634) Escherichia coli O157:H7 str. TW14359 8216197 YP_003077547.1 CDS ychE NC_013008.1 1663111 1663758 D hypothetical protein 1663111..1663758 Escherichia coli O157:H7 str. TW14359 8216198 YP_003077548.1 CDS ECSP_1633 NC_013008.1 1663785 1663940 D hypothetical protein 1663785..1663940 Escherichia coli O157:H7 str. TW14359 8216199 YP_003077549.1 CDS ECSP_1634 NC_013008.1 1663916 1664077 R hypothetical protein complement(1663916..1664077) Escherichia coli O157:H7 str. TW14359 8216200 YP_003077550.1 CDS oppA NC_013008.1 1664496 1666127 D oligopeptide ABC transporter periplasmic-binding protein 1664496..1666127 Escherichia coli O157:H7 str. TW14359 8216201 YP_003077551.1 CDS oppB NC_013008.1 1666213 1667133 D oligopeptide transporter permease 1666213..1667133 Escherichia coli O157:H7 str. TW14359 8216202 YP_003077552.1 CDS oppC NC_013008.1 1667148 1668056 D oligopeptide ABC transporter membrane protein 1667148..1668056 Escherichia coli O157:H7 str. TW14359 8216203 YP_003077553.1 CDS oppD NC_013008.1 1668068 1669081 D oligopeptide transporter ATP-binding protein 1668068..1669081 Escherichia coli O157:H7 str. TW14359 8216204 YP_003077554.1 CDS oppF NC_013008.1 1669078 1670082 D oligopeptide ABC transporter ATP-binding protein 1669078..1670082 Escherichia coli O157:H7 str. TW14359 8216205 YP_003077555.1 CDS yciU NC_013008.1 1670135 1670464 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1670135..1670464) Escherichia coli O157:H7 str. TW14359 8216206 YP_003077556.1 CDS cls NC_013008.1 1670499 1671959 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1670499..1671959) Escherichia coli O157:H7 str. TW14359 8216207 YP_003077557.1 CDS kch NC_013008.1 1672330 1673583 R voltage-gated potassium channel complement(1672330..1673583) Escherichia coli O157:H7 str. TW14359 8216208 YP_003077558.1 CDS yciI NC_013008.1 1673884 1674180 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein complement(1673884..1674180) Escherichia coli O157:H7 str. TW14359 8216209 YP_003077559.1 CDS tonB NC_013008.1 1674404 1675123 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1674404..1675123 Escherichia coli O157:H7 str. TW14359 8216210 YP_003077560.1 CDS yciA NC_013008.1 1675163 1675561 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1675163..1675561) Escherichia coli O157:H7 str. TW14359 8216211 YP_003077561.1 CDS yciB NC_013008.1 1675666 1676205 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1675666..1676205) Escherichia coli O157:H7 str. TW14359 8216212 YP_003077562.1 CDS yciC NC_013008.1 1676235 1676978 R hypothetical protein complement(1676235..1676978) Escherichia coli O157:H7 str. TW14359 8216213 YP_003077563.1 CDS ompW NC_013008.1 1677335 1677973 D receptor for colicin S4; outer membrane protein W 1677335..1677973 Escherichia coli O157:H7 str. TW14359 8216214 YP_003077564.1 CDS intO NC_013008.1 1678019 1679149 R integrase for prophage CP-933O complement(1678019..1679149) Escherichia coli O157:H7 str. TW14359 8216215 YP_003077565.1 CDS exoO NC_013008.1 1679440 1681911 R exonuclease VIII, ds DNA exonuclease, 5' --> 3' specific encoded by prophage CP-933O complement(1679440..1681911) Escherichia coli O157:H7 str. TW14359 8216216 YP_003077566.1 CDS ECSP_1651 NC_013008.1 1682939 1683172 D hypothetical protein 1682939..1683172 Escherichia coli O157:H7 str. TW14359 8216217 YP_003077567.1 CDS ECSP_1652 NC_013008.1 1683150 1683557 R hypothetical protein complement(1683150..1683557) Escherichia coli O157:H7 str. TW14359 8216218 YP_003077568.1 CDS ECSP_1653 NC_013008.1 1683580 1683798 R hypothetical protein complement(1683580..1683798) Escherichia coli O157:H7 str. TW14359 8216219 YP_003077569.1 CDS ECSP_1654 NC_013008.1 1683871 1684170 R hypothetical protein complement(1683871..1684170) Escherichia coli O157:H7 str. TW14359 8216220 YP_003077570.1 CDS ECSP_1655 NC_013008.1 1684434 1684841 R encoded by prophage CP-933O; The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown; transcriptional repressor DicA complement(1684434..1684841) Escherichia coli O157:H7 str. TW14359 8216221 YP_003077571.1 CDS ECSP_1656 NC_013008.1 1684918 1685145 D DNA-binding transcriptional regulator DicC 1684918..1685145 Escherichia coli O157:H7 str. TW14359 8216222 YP_003077572.1 CDS ECSP_1657 NC_013008.1 1685129 1685680 D hypothetical protein 1685129..1685680 Escherichia coli O157:H7 str. TW14359 8216223 YP_003077573.1 CDS ECSP_1658 NC_013008.1 1685652 1686692 D hypothetical protein 1685652..1686692 Escherichia coli O157:H7 str. TW14359 8216224 YP_003077574.1 CDS ECSP_1659 NC_013008.1 1686724 1687146 D hypothetical protein 1686724..1687146 Escherichia coli O157:H7 str. TW14359 8216225 YP_003077575.1 CDS ECSP_1660 NC_013008.1 1687333 1687914 D hypothetical protein 1687333..1687914 Escherichia coli O157:H7 str. TW14359 8216226 YP_003077576.1 CDS ECSP_1661 NC_013008.1 1687950 1688075 D hypothetical protein 1687950..1688075 Escherichia coli O157:H7 str. TW14359 8216227 YP_003077577.1 CDS ECSP_1663 NC_013008.1 1688786 1689532 D colonization factor 1688786..1689532 Escherichia coli O157:H7 str. TW14359 8216229 YP_003077578.1 CDS ECSP_1664 NC_013008.1 1689811 1690023 D killer protein encoded by prophage CP-933O 1689811..1690023 Escherichia coli O157:H7 str. TW14359 8216230 YP_003077579.1 CDS ECSP_1665 NC_013008.1 1690244 1690501 D hypothetical protein 1690244..1690501 Escherichia coli O157:H7 str. TW14359 8216231 YP_003077580.1 CDS ECSP_1666 NC_013008.1 1690571 1690849 D hypothetical protein 1690571..1690849 Escherichia coli O157:H7 str. TW14359 8216232 YP_003077581.1 CDS ECSP_1667 NC_013008.1 1690851 1691897 D hypothetical protein 1690851..1691897 Escherichia coli O157:H7 str. TW14359 8216233 YP_003077582.1 CDS ECSP_1668 NC_013008.1 1691910 1692269 D endonuclease of prophage CP-933O 1691910..1692269 Escherichia coli O157:H7 str. TW14359 8216234 YP_003077583.1 CDS ECSP_1669 NC_013008.1 1692278 1692808 D hypothetical protein 1692278..1692808 Escherichia coli O157:H7 str. TW14359 8216235 YP_003077584.1 CDS ECSP_1670 NC_013008.1 1692927 1693247 D hypothetical protein 1692927..1693247 Escherichia coli O157:H7 str. TW14359 8216236 YP_003077585.1 CDS ECSP_1671 NC_013008.1 1693398 1694456 D DNA adenine methyltransferase encoded by prophage CP-933O 1693398..1694456 Escherichia coli O157:H7 str. TW14359 8216237 YP_003077586.1 CDS ECSP_1674 NC_013008.1 1695534 1696073 D hypothetical protein 1695534..1696073 Escherichia coli O157:H7 str. TW14359 8216240 YP_003077587.1 CDS ECSP_1675 NC_013008.1 1696124 1696438 D holin protein 1696124..1696438 Escherichia coli O157:H7 str. TW14359 8216241 YP_003077588.1 CDS ECSP_1676 NC_013008.1 1696440 1696787 D hypothetical protein 1696440..1696787 Escherichia coli O157:H7 str. TW14359 8216242 YP_003077589.1 CDS ECSP_1677 NC_013008.1 1696838 1697371 D endolysin encoded by cryptic prophage CP-933P 1696838..1697371 Escherichia coli O157:H7 str. TW14359 8216243 YP_003077590.1 CDS ECSP_1678 NC_013008.1 1697642 1698211 D antirepressor protein encoded by cryptic prophage CP-933 1697642..1698211 Escherichia coli O157:H7 str. TW14359 8216244 YP_003077591.1 CDS ECSP_1679 NC_013008.1 1698365 1698832 D endopeptidase of prophage CP-933 1698365..1698832 Escherichia coli O157:H7 str. TW14359 8216245 YP_003077592.1 CDS ECSP_1680 NC_013008.1 1700303 1700848 D DNA packaging protein of prophage CP-933X 1700303..1700848 Escherichia coli O157:H7 str. TW14359 8216246 YP_003077593.1 CDS ECSP_1681 NC_013008.1 1701003 1702748 D DNA packaging protein of prophage CP-933X 1701003..1702748 Escherichia coli O157:H7 str. TW14359 8216247 YP_003077594.1 CDS ECSP_1682 NC_013008.1 1702948 1704549 D capsid structural protein of prophage CP-933X 1702948..1704549 Escherichia coli O157:H7 str. TW14359 8216248 YP_003077595.1 CDS ECSP_1683 NC_013008.1 1704530 1705849 D capsid protein of prophage CP-933X 1704530..1705849 Escherichia coli O157:H7 str. TW14359 8216249 YP_003077596.1 CDS ECSP_1684 NC_013008.1 1706247 1707272 D capsid protein of prophage CP-933X 1706247..1707272 Escherichia coli O157:H7 str. TW14359 8216250 YP_003077597.1 CDS ECSP_1685 NC_013008.1 1707275 1707712 D DNA packaging protein of prophage CP-933X 1707275..1707712 Escherichia coli O157:H7 str. TW14359 8216251 YP_003077598.1 CDS ECSP_1686 NC_013008.1 1707724 1708077 D head-tail joining protein of prophage CP-933X 1707724..1708077 Escherichia coli O157:H7 str. TW14359 8216252 YP_003077599.1 CDS ECSP_1687 NC_013008.1 1708092 1708625 D hypothetical protein 1708092..1708625 Escherichia coli O157:H7 str. TW14359 8216253 YP_003077600.1 CDS ECSP_1688 NC_013008.1 1708622 1709017 D tail fiber component U of prophage CP-933U 1708622..1709017 Escherichia coli O157:H7 str. TW14359 8216254 YP_003077601.1 CDS ECSP_1689 NC_013008.1 1709025 1709777 D tail fiber component V of prophage CP-933U 1709025..1709777 Escherichia coli O157:H7 str. TW14359 8216255 YP_003077602.1 CDS ECSP_1690 NC_013008.1 1709791 1710213 D tail fiber component G of prophage CP-933U 1709791..1710213 Escherichia coli O157:H7 str. TW14359 8216256 YP_003077603.1 CDS ECSP_1691 NC_013008.1 1710240 1710548 D tail fiber component T of prophage CP-933U 1710240..1710548 Escherichia coli O157:H7 str. TW14359 8216257 YP_003077604.1 CDS ECSP_1692 NC_013008.1 1710592 1713237 D tail fiber component H of prophage CP-933U 1710592..1713237 Escherichia coli O157:H7 str. TW14359 8216258 YP_003077605.1 CDS ECSP_1693 NC_013008.1 1713234 1713563 D tail component of prophage CP-933O 1713234..1713563 Escherichia coli O157:H7 str. TW14359 8216259 YP_003077606.1 CDS ECSP_1694 NC_013008.1 1713563 1714261 D tail component of prophage CP-933O 1713563..1714261 Escherichia coli O157:H7 str. TW14359 8216260 YP_003077607.1 CDS ECSP_1695 NC_013008.1 1714380 1715015 D tail component of prophage CP-933O 1714380..1715015 Escherichia coli O157:H7 str. TW14359 8216261 YP_003077608.1 CDS ECSP_1696 NC_013008.1 1715012 1715590 D tail assembly protein of cryptic prophage CP-933P 1715012..1715590 Escherichia coli O157:H7 str. TW14359 8216262 YP_003077609.1 CDS ECSP_1697 NC_013008.1 1715831 1718686 D tail component of cryptic prophage CP-933P 1715831..1718686 Escherichia coli O157:H7 str. TW14359 8216263 YP_003077610.1 CDS lomP NC_013008.1 1718754 1719353 D Lom-like outer membrane protein of cryptic prophage CP-933P 1718754..1719353 Escherichia coli O157:H7 str. TW14359 8216264 YP_003077611.1 CDS ECSP_1699 NC_013008.1 1719505 1720809 D tail fiber protein of cryptic prophage CP-933P 1719505..1720809 Escherichia coli O157:H7 str. TW14359 8216265 YP_003077612.1 CDS ECSP_1700 NC_013008.1 1720811 1721080 D hypothetical protein 1720811..1721080 Escherichia coli O157:H7 str. TW14359 8216266 YP_003077613.1 CDS ECSP_1701 NC_013008.1 1721237 1721767 D hypothetical protein 1721237..1721767 Escherichia coli O157:H7 str. TW14359 8216267 YP_003077614.1 CDS nleA NC_013008.1 1722107 1723432 R non-LEE-encoded type III effector complement(1722107..1723432) Escherichia coli O157:H7 str. TW14359 8216268 YP_003077615.1 CDS ECSP_1703 NC_013008.1 1724093 1724785 R integrase complement(1724093..1724785) Escherichia coli O157:H7 str. TW14359 8216269 YP_003077616.1 CDS nleH2 NC_013008.1 1725259 1726170 D non-LEE-encoded type III effector 1725259..1726170 Escherichia coli O157:H7 str. TW14359 8216270 YP_003077617.1 CDS nleF NC_013008.1 1726236 1726805 D non-LEE-encoded type III effector 1726236..1726805 Escherichia coli O157:H7 str. TW14359 8216271 YP_003077618.1 CDS ECSP_1707 NC_013008.1 1727771 1729309 R transposase ISEc8 complement(1727771..1729309) Escherichia coli O157:H7 str. TW14359 8216273 YP_003077619.1 CDS ECSP_1708 NC_013008.1 1729359 1729706 R transposase complement(1729359..1729706) Escherichia coli O157:H7 str. TW14359 8216274 YP_003077620.1 CDS ECSP_1709 NC_013008.1 1729703 1730104 R transposase complement(1729703..1730104) Escherichia coli O157:H7 str. TW14359 8216275 YP_003077621.1 CDS ECSP_1710 NC_013008.1 1730423 1730701 R non-LEE-encoded type III effector complement(1730423..1730701) Escherichia coli O157:H7 str. TW14359 8216276 YP_003077622.1 CDS ECSP_1711 NC_013008.1 1731412 1732059 R non-LEE-encoded type III effector complement(1731412..1732059) Escherichia coli O157:H7 str. TW14359 8216277 YP_003077623.1 CDS espM1 NC_013008.1 1732243 1732833 D non-LEE-encoded type III effector 1732243..1732833 Escherichia coli O157:H7 str. TW14359 8216278 YP_003077624.1 CDS ECSP_1716 NC_013008.1 1736291 1737421 R integrase for prophage CP-933O complement(1736291..1737421) Escherichia coli O157:H7 str. TW14359 8216282 YP_003077625.1 CDS ECSP_1717 NC_013008.1 1737712 1740156 R exodeoxyribonuclease VIII complement(1737712..1740156) Escherichia coli O157:H7 str. TW14359 8216283 YP_003077626.1 CDS ECSP_1718 NC_013008.1 1740249 1740377 R hypothetical protein complement(1740249..1740377) Escherichia coli O157:H7 str. TW14359 8216284 YP_003077627.1 CDS ECSP_1719 NC_013008.1 1740531 1740722 D O antigen biosynthesis protein 1740531..1740722 Escherichia coli O157:H7 str. TW14359 8216285 YP_003077628.1 CDS ECSP_1720 NC_013008.1 1740849 1741184 D hypothetical protein 1740849..1741184 Escherichia coli O157:H7 str. TW14359 8216286 YP_003077629.1 CDS ECSP_1721 NC_013008.1 1741188 1741406 R hypothetical protein complement(1741188..1741406) Escherichia coli O157:H7 str. TW14359 8216287 YP_003077630.1 CDS ECSP_1722 NC_013008.1 1741436 1741564 R hypothetical protein complement(1741436..1741564) Escherichia coli O157:H7 str. TW14359 8216288 YP_003077631.1 CDS ECSP_1723 NC_013008.1 1741566 1741721 R hypothetical protein complement(1741566..1741721) Escherichia coli O157:H7 str. TW14359 8216289 YP_003077632.1 CDS ECSP_1724 NC_013008.1 1741911 1742318 R The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA complement(1741911..1742318) Escherichia coli O157:H7 str. TW14359 8216290 YP_003077633.1 CDS ECSP_1725 NC_013008.1 1742667 1743158 D hypothetical protein 1742667..1743158 Escherichia coli O157:H7 str. TW14359 8216291 YP_003077634.1 CDS ECSP_1726 NC_013008.1 1743130 1744170 D hypothetical protein 1743130..1744170 Escherichia coli O157:H7 str. TW14359 8216292 YP_003077635.1 CDS ECSP_1727 NC_013008.1 1744163 1744624 D hypothetical protein 1744163..1744624 Escherichia coli O157:H7 str. TW14359 8216293 YP_003077636.1 CDS ECSP_1728 NC_013008.1 1744659 1745429 D hypothetical protein 1744659..1745429 Escherichia coli O157:H7 str. TW14359 8216294 YP_003077637.1 CDS ECSP_1729 NC_013008.1 1745445 1745840 D hypothetical protein 1745445..1745840 Escherichia coli O157:H7 str. TW14359 8216295 YP_003077638.1 CDS ECSP_1730 NC_013008.1 1745897 1746253 D hypothetical protein 1745897..1746253 Escherichia coli O157:H7 str. TW14359 8216296 YP_003077639.1 CDS ECSP_1731 NC_013008.1 1746302 1746514 D hypothetical protein 1746302..1746514 Escherichia coli O157:H7 str. TW14359 8216297 YP_003077640.1 CDS ECSP_1732 NC_013008.1 1746550 1746921 D hypothetical protein 1746550..1746921 Escherichia coli O157:H7 str. TW14359 8216298 YP_003077641.1 CDS ECSP_1733 NC_013008.1 1746918 1747280 D hypothetical protein 1746918..1747280 Escherichia coli O157:H7 str. TW14359 8216299 YP_003077642.1 CDS ECSP_1734 NC_013008.1 1747351 1747500 D hypothetical protein 1747351..1747500 Escherichia coli O157:H7 str. TW14359 8216300 YP_003077643.1 CDS ECSP_1735 NC_013008.1 1748122 1748379 D hypothetical protein 1748122..1748379 Escherichia coli O157:H7 str. TW14359 8216301 YP_003077644.1 CDS ECSP_1736 NC_013008.1 1748449 1748727 D hypothetical protein 1748449..1748727 Escherichia coli O157:H7 str. TW14359 8216302 YP_003077645.1 CDS ECSP_1737 NC_013008.1 1748729 1749778 D hypothetical protein 1748729..1749778 Escherichia coli O157:H7 str. TW14359 8216303 YP_003077646.1 CDS ECSP_1738 NC_013008.1 1749791 1750165 D endodeoxyribonuclease RusA 1749791..1750165 Escherichia coli O157:H7 str. TW14359 8216304 YP_003077647.1 CDS ECSP_1739 NC_013008.1 1750162 1750983 D antitermination protein Q-like protein of cryptic prophage CP-933M 1750162..1750983 Escherichia coli O157:H7 str. TW14359 8216305 YP_003077648.1 CDS ECSP_1740 NC_013008.1 1751210 1751407 D hypothetical protein 1751210..1751407 Escherichia coli O157:H7 str. TW14359 8216306 YP_003077649.1 CDS ECSP_1741 NC_013008.1 1751429 1751530 D hypothetical protein 1751429..1751530 Escherichia coli O157:H7 str. TW14359 8216307 YP_003077650.1 CDS ECSP_1742 NC_013008.1 1751558 1752616 D DNA methylase 1751558..1752616 Escherichia coli O157:H7 str. TW14359 8216308 YP_003077651.1 CDS ECSP_1744 NC_013008.1 1752824 1752970 R hypothetical protein complement(1752824..1752970) Escherichia coli O157:H7 str. TW14359 8216310 YP_003077652.1 CDS ECSP_1745 NC_013008.1 1753211 1755157 D hypothetical protein 1753211..1755157 Escherichia coli O157:H7 str. TW14359 8216311 YP_003077653.1 CDS ECSP_1746 NC_013008.1 1755338 1755757 D hypothetical protein 1755338..1755757 Escherichia coli O157:H7 str. TW14359 8216312 YP_003077654.1 CDS ECSP_1747 NC_013008.1 1755760 1756050 D lysis protein 1755760..1756050 Escherichia coli O157:H7 str. TW14359 8216313 YP_003077655.1 CDS ECSP_1748 NC_013008.1 1756054 1756611 D hypothetical protein 1756054..1756611 Escherichia coli O157:H7 str. TW14359 8216314 YP_003077656.1 CDS ECSP_1749 NC_013008.1 1756648 1757181 D endolysin 1756648..1757181 Escherichia coli O157:H7 str. TW14359 8216315 YP_003077657.1 CDS ECSP_1750 NC_013008.1 1757480 1757947 D bacteriophage lysis protein 1757480..1757947 Escherichia coli O157:H7 str. TW14359 8216316 YP_003077658.1 CDS ECSP_1751 NC_013008.1 1758360 1758836 D hypothetical protein 1758360..1758836 Escherichia coli O157:H7 str. TW14359 8216317 YP_003077659.1 CDS ECSP_1752 NC_013008.1 1758833 1760956 D terminase large subunit 1758833..1760956 Escherichia coli O157:H7 str. TW14359 8216318 YP_003077660.1 CDS ECSP_1753 NC_013008.1 1761165 1762667 D phage portal protein, lambda family 1761165..1762667 Escherichia coli O157:H7 str. TW14359 8216319 YP_003077661.1 CDS ECSP_1754 NC_013008.1 1762681 1764636 D protease 1762681..1764636 Escherichia coli O157:H7 str. TW14359 8216320 YP_003077662.1 CDS ECSP_1755 NC_013008.1 1764724 1765050 D hypothetical protein 1764724..1765050 Escherichia coli O157:H7 str. TW14359 8216321 YP_003077663.1 CDS ECSP_1756 NC_013008.1 1765076 1765324 D hypothetical protein 1765076..1765324 Escherichia coli O157:H7 str. TW14359 8216322 YP_003077664.1 CDS ECSP_1757 NC_013008.1 1765327 1765950 D prophage minor tail protein Z 1765327..1765950 Escherichia coli O157:H7 str. TW14359 8216323 YP_003077665.1 CDS ECSP_1758 NC_013008.1 1765963 1766361 D phage minor tail protein U 1765963..1766361 Escherichia coli O157:H7 str. TW14359 8216324 YP_003077666.1 CDS ECSP_1759 NC_013008.1 1766369 1767121 D tail fiber component 1766369..1767121 Escherichia coli O157:H7 str. TW14359 8216325 YP_003077667.1 CDS ECSP_1760 NC_013008.1 1767135 1767557 D minor tail protein 1767135..1767557 Escherichia coli O157:H7 str. TW14359 8216326 YP_003077668.1 CDS ECSP_1761 NC_013008.1 1767608 1767892 D tail assembly protein T 1767608..1767892 Escherichia coli O157:H7 str. TW14359 8216327 YP_003077669.1 CDS ECSP_1762 NC_013008.1 1767936 1770581 D tail fiber component H 1767936..1770581 Escherichia coli O157:H7 str. TW14359 8216328 YP_003077670.1 CDS ECSP_1763 NC_013008.1 1770578 1770907 D phage minor tail protein 1770578..1770907 Escherichia coli O157:H7 str. TW14359 8216329 YP_003077671.1 CDS ECSP_1764 NC_013008.1 1770907 1771605 D tail fiber component L 1770907..1771605 Escherichia coli O157:H7 str. TW14359 8216330 YP_003077672.1 CDS ECSP_1765 NC_013008.1 1771724 1772359 D hypothetical protein 1771724..1772359 Escherichia coli O157:H7 str. TW14359 8216331 YP_003077673.1 CDS ECSP_1766 NC_013008.1 1772356 1772934 D tail assembly protein 1772356..1772934 Escherichia coli O157:H7 str. TW14359 8216332 YP_003077674.1 CDS ECSP_1767 NC_013008.1 1773175 1776651 D host specificity protein J 1773175..1776651 Escherichia coli O157:H7 str. TW14359 8216333 YP_003077675.1 CDS ECSP_1768 NC_013008.1 1776719 1777318 D outer membrane protein Lom 1776719..1777318 Escherichia coli O157:H7 str. TW14359 8216334 YP_003077676.1 CDS ECSP_1769 NC_013008.1 1777383 1778696 D tail fiber protein 1777383..1778696 Escherichia coli O157:H7 str. TW14359 8216335 YP_003077677.1 CDS ECSP_1770 NC_013008.1 1778698 1778967 D tail fiber protein 1778698..1778967 Escherichia coli O157:H7 str. TW14359 8216336 YP_003077678.1 CDS ECSP_1771 NC_013008.1 1779227 1779502 D IS1 transposase 1779227..1779502 Escherichia coli O157:H7 str. TW14359 8216337 YP_003077679.1 CDS ECSP_1772 NC_013008.1 1779529 1779924 D IS1 transposase 1779529..1779924 Escherichia coli O157:H7 str. TW14359 8216338 YP_003077680.1 CDS ospG NC_013008.1 1780100 1780690 D hypothetical protein 1780100..1780690 Escherichia coli O157:H7 str. TW14359 8216339 YP_003077681.1 CDS ECSP_1774 NC_013008.1 1780930 1781238 D hypothetical protein 1780930..1781238 Escherichia coli O157:H7 str. TW14359 8216340 YP_003077682.1 CDS ECSP_1775 NC_013008.1 1781552 1781668 D hypothetical protein 1781552..1781668 Escherichia coli O157:H7 str. TW14359 8216341 YP_003077683.1 CDS yciE NC_013008.1 1781728 1782234 R hypothetical protein complement(1781728..1782234) Escherichia coli O157:H7 str. TW14359 8216342 YP_003077684.1 CDS yciF NC_013008.1 1782280 1782780 R hypothetical protein complement(1782280..1782780) Escherichia coli O157:H7 str. TW14359 8216343 YP_003077685.1 CDS ECSP_1778 NC_013008.1 1782866 1783045 R hypothetical protein complement(1782866..1783045) Escherichia coli O157:H7 str. TW14359 8216344 YP_003077686.1 CDS trpA NC_013008.1 1783426 1784232 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1783426..1784232) Escherichia coli O157:H7 str. TW14359 8216345 YP_003077687.1 CDS trpB NC_013008.1 1784232 1785425 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1784232..1785425) Escherichia coli O157:H7 str. TW14359 8216346 YP_003077688.1 CDS trpC NC_013008.1 1785437 1786795 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1785437..1786795) Escherichia coli O157:H7 str. TW14359 8216347 YP_003077689.1 CDS trpD NC_013008.1 1786799 1788394 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1786799..1788394) Escherichia coli O157:H7 str. TW14359 8216348 YP_003077690.1 CDS trpE NC_013008.1 1788394 1789956 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1788394..1789956) Escherichia coli O157:H7 str. TW14359 8216349 YP_003077691.1 CDS yciV NC_013008.1 1790230 1791111 D hypothetical protein 1790230..1791111 Escherichia coli O157:H7 str. TW14359 8216350 YP_003077692.1 CDS yciO NC_013008.1 1791108 1791728 D hypothetical protein 1791108..1791728 Escherichia coli O157:H7 str. TW14359 8216351 YP_003077693.1 CDS ECSP_1786 NC_013008.1 1791756 1793339 D hypothetical protein 1791756..1793339 Escherichia coli O157:H7 str. TW14359 8216352 YP_003077694.1 CDS rluB NC_013008.1 1793552 1794424 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1793552..1794424 Escherichia coli O157:H7 str. TW14359 8216353 YP_003077695.1 CDS btuR NC_013008.1 1794464 1795054 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1794464..1795054) Escherichia coli O157:H7 str. TW14359 8216354 YP_003077696.1 CDS yciK NC_013008.1 1795051 1795809 R short chain dehydrogenase complement(1795051..1795809) Escherichia coli O157:H7 str. TW14359 8216355 YP_003077697.1 CDS sohB NC_013008.1 1796029 1797078 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1796029..1797078 Escherichia coli O157:H7 str. TW14359 8216356 YP_003077698.1 CDS yciN NC_013008.1 1797114 1797365 R hypothetical protein complement(1797114..1797365) Escherichia coli O157:H7 str. TW14359 8216357 YP_003077699.1 CDS topA NC_013008.1 1797745 1800342 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1797745..1800342 Escherichia coli O157:H7 str. TW14359 8216358 YP_003077700.1 CDS cysB NC_013008.1 1800552 1801526 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1800552..1801526 Escherichia coli O157:H7 str. TW14359 8216359 YP_003077701.1 CDS ECSP_1794 NC_013008.1 1801857 1801985 D hypothetical protein 1801857..1801985 Escherichia coli O157:H7 str. TW14359 8216360 YP_003077702.1 CDS yciX NC_013008.1 1801988 1802155 D hypothetical protein 1801988..1802155 Escherichia coli O157:H7 str. TW14359 8216361 YP_003077703.1 CDS acnA NC_013008.1 1802528 1805203 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1802528..1805203 Escherichia coli O157:H7 str. TW14359 8216362 YP_003077704.1 CDS ribA NC_013008.1 1805267 1805857 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1805267..1805857) Escherichia coli O157:H7 str. TW14359 8216363 YP_003077705.1 CDS pgpB NC_013008.1 1806027 1806791 D phosphatidylglycerophosphatase B 1806027..1806791 Escherichia coli O157:H7 str. TW14359 8216364 YP_003077706.1 CDS yciS NC_013008.1 1806940 1807248 D hypothetical protein 1806940..1807248 Escherichia coli O157:H7 str. TW14359 8216365 YP_003077707.1 CDS yciM NC_013008.1 1807255 1808424 D hypothetical protein 1807255..1808424 Escherichia coli O157:H7 str. TW14359 8216366 YP_003077708.1 CDS pyrF NC_013008.1 1808617 1809354 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1808617..1809354 Escherichia coli O157:H7 str. TW14359 8216367 YP_003077709.1 CDS yciH NC_013008.1 1809354 1809680 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1809354..1809680 Escherichia coli O157:H7 str. TW14359 8216368 YP_003077710.1 CDS osmB NC_013008.1 1809806 1810024 R lipoprotein complement(1809806..1810024) Escherichia coli O157:H7 str. TW14359 8216369 YP_003077711.1 CDS yciT NC_013008.1 1810293 1811042 R DNA-binding transcriptional regulator complement(1810293..1811042) Escherichia coli O157:H7 str. TW14359 8216370 YP_003077712.1 CDS ECSP_1805 NC_013008.1 1811132 1811314 R hypothetical protein complement(1811132..1811314) Escherichia coli O157:H7 str. TW14359 8216371 YP_003077713.1 CDS gmr NC_013008.1 1811856 1813433 R modulator of Rnase II stability complement(1811856..1813433) Escherichia coli O157:H7 str. TW14359 8216372 YP_003077714.1 CDS rnb NC_013008.1 1813668 1815602 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1813668..1815602) Escherichia coli O157:H7 str. TW14359 8216373 YP_003077715.1 CDS yciW NC_013008.1 1815670 1816797 R oxidoreductase complement(1815670..1816797) Escherichia coli O157:H7 str. TW14359 8216374 YP_003077716.1 CDS fabI NC_013008.1 1816941 1817729 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(1816941..1817729) Escherichia coli O157:H7 str. TW14359 8216375 YP_003077717.1 CDS ECSP_1810 NC_013008.1 1818207 1818773 D transcriptional repressor 1818207..1818773 Escherichia coli O157:H7 str. TW14359 8216376 YP_003077718.1 CDS ECSP_1811 NC_013008.1 1818922 1820043 D efflux pump 1818922..1820043 Escherichia coli O157:H7 str. TW14359 8216377 YP_003077719.1 CDS ECSP_1812 NC_013008.1 1820043 1823132 D efflux pump 1820043..1823132 Escherichia coli O157:H7 str. TW14359 8216378 YP_003077720.1 CDS ECSP_1813 NC_013008.1 1823155 1824528 D outer membrane channel protein 1823155..1824528 Escherichia coli O157:H7 str. TW14359 8216379 YP_003077721.1 CDS ECSP_1814 NC_013008.1 1824537 1825700 D membrane transport protein 1824537..1825700 Escherichia coli O157:H7 str. TW14359 8216380 YP_003077722.1 CDS sapF NC_013008.1 1825752 1826558 R peptide transport system ATP-binding protein complement(1825752..1826558) Escherichia coli O157:H7 str. TW14359 8216381 YP_003077723.1 CDS sapD NC_013008.1 1826560 1827552 R peptide transport system ATP-binding protein complement(1826560..1827552) Escherichia coli O157:H7 str. TW14359 8216382 YP_003077724.1 CDS sapC NC_013008.1 1827552 1828442 R antimicrobial peptide ABC transporter membrane protein complement(1827552..1828442) Escherichia coli O157:H7 str. TW14359 8216383 YP_003077725.1 CDS sapB NC_013008.1 1828429 1829394 R antimicrobial peptide ABC transporter membrane protein complement(1828429..1829394) Escherichia coli O157:H7 str. TW14359 8216384 YP_003077726.1 CDS sapA NC_013008.1 1829391 1831034 R antimicrobial peptide transporter subunit complement(1829391..1831034) Escherichia coli O157:H7 str. TW14359 8216385 YP_003077727.1 CDS ymjA NC_013008.1 1831347 1831592 R hypothetical protein complement(1831347..1831592) Escherichia coli O157:H7 str. TW14359 8216386 YP_003077728.1 CDS puuP NC_013008.1 1831726 1833111 R putrescine importer complement(1831726..1833111) Escherichia coli O157:H7 str. TW14359 8216387 YP_003077729.1 CDS puuA NC_013008.1 1833414 1834832 R gamma-Glu-putrescine synthase complement(1833414..1834832) Escherichia coli O157:H7 str. TW14359 8216388 YP_003077730.1 CDS puuD NC_013008.1 1835044 1835808 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1835044..1835808 Escherichia coli O157:H7 str. TW14359 8216389 YP_003077731.1 CDS puuR NC_013008.1 1835835 1836392 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1835835..1836392 Escherichia coli O157:H7 str. TW14359 8216390 YP_003077732.1 CDS puuC NC_013008.1 1836542 1838029 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1836542..1838029 Escherichia coli O157:H7 str. TW14359 8216391 YP_003077733.1 CDS puuB NC_013008.1 1838031 1839311 D gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding 1838031..1839311 Escherichia coli O157:H7 str. TW14359 8216392 YP_003077734.1 CDS puuE NC_013008.1 1839349 1840614 D putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 1839349..1840614 Escherichia coli O157:H7 str. TW14359 8216393 YP_003077735.1 CDS pspF NC_013008.1 1840745 1841722 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1840745..1841722) Escherichia coli O157:H7 str. TW14359 8216394 YP_003077736.1 CDS pspA NC_013008.1 1841889 1842557 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1841889..1842557 Escherichia coli O157:H7 str. TW14359 8216395 YP_003077737.1 CDS pspB NC_013008.1 1842611 1842835 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1842611..1842835 Escherichia coli O157:H7 str. TW14359 8216396 YP_003077738.1 CDS pspC NC_013008.1 1842835 1843194 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1842835..1843194 Escherichia coli O157:H7 str. TW14359 8216397 YP_003077739.1 CDS pspD NC_013008.1 1843203 1843424 D peripheral inner membrane phage-shock protein 1843203..1843424 Escherichia coli O157:H7 str. TW14359 8216398 YP_003077740.1 CDS pspE NC_013008.1 1843499 1843813 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1843499..1843813 Escherichia coli O157:H7 str. TW14359 8216399 YP_003077741.1 CDS ycjO NC_013008.1 1847028 1847909 D sugar ABC transporter membrane protein 1847028..1847909 Escherichia coli O157:H7 str. TW14359 8216402 YP_003077742.1 CDS ycjP NC_013008.1 1847896 1848738 D sugar ABC transporter membrane protein 1847896..1848738 Escherichia coli O157:H7 str. TW14359 8216403 YP_003077743.1 CDS ycjQ NC_013008.1 1848769 1849821 D oxidoreductase 1848769..1849821 Escherichia coli O157:H7 str. TW14359 8216404 YP_003077744.1 CDS ycjR NC_013008.1 1849839 1850627 D hypothetical protein 1849839..1850627 Escherichia coli O157:H7 str. TW14359 8216405 YP_003077745.1 CDS ycjS NC_013008.1 1850637 1851692 D oxidoreductase 1850637..1851692 Escherichia coli O157:H7 str. TW14359 8216406 YP_003077746.1 CDS ycjT NC_013008.1 1851689 1853956 D hydrolase 1851689..1853956 Escherichia coli O157:H7 str. TW14359 8216407 YP_003077747.1 CDS ycjU NC_013008.1 1853953 1854612 D beta-phosphoglucomutase 1853953..1854612 Escherichia coli O157:H7 str. TW14359 8216408 YP_003077748.1 CDS ycjV NC_013008.1 1854626 1855708 D ATP-binding protein of a transport system 1854626..1855708 Escherichia coli O157:H7 str. TW14359 8216409 YP_003077749.1 CDS ompG NC_013008.1 1855753 1856658 D outer membrane porin 1855753..1856658 Escherichia coli O157:H7 str. TW14359 8216410 YP_003077750.1 CDS ycjW NC_013008.1 1856769 1857767 R DNA-binding transcriptional regulator complement(1856769..1857767) Escherichia coli O157:H7 str. TW14359 8216411 YP_003077751.1 CDS ycjX NC_013008.1 1857922 1859319 D hypothetical protein 1857922..1859319 Escherichia coli O157:H7 str. TW14359 8216412 YP_003077752.1 CDS ycjF NC_013008.1 1859316 1860377 D hypothetical protein 1859316..1860377 Escherichia coli O157:H7 str. TW14359 8216413 YP_003077753.1 CDS tyrR NC_013008.1 1860525 1862066 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1860525..1862066 Escherichia coli O157:H7 str. TW14359 8216414 YP_003077754.1 CDS tpx NC_013008.1 1862110 1862616 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1862110..1862616) Escherichia coli O157:H7 str. TW14359 8216415 YP_003077755.1 CDS ycjG NC_013008.1 1862735 1863700 D L-Ala-D/L-Glu epimerase 1862735..1863700 Escherichia coli O157:H7 str. TW14359 8216416 YP_003077756.1 CDS mpaA NC_013008.1 1863675 1864403 R murein peptide amidase A complement(1863675..1864403) Escherichia coli O157:H7 str. TW14359 8216417 YP_003077757.1 CDS ECSP_1852 NC_013008.1 1864694 1865332 R hypothetical protein complement(1864694..1865332) Escherichia coli O157:H7 str. TW14359 8216418 YP_003077758.1 CDS ycjY NC_013008.1 1866283 1867203 R hydrolase complement(1866283..1867203) Escherichia coli O157:H7 str. TW14359 8216420 YP_003077759.1 CDS ycjZ NC_013008.1 1867341 1868240 D DNA-binding transcriptional regulator 1867341..1868240 Escherichia coli O157:H7 str. TW14359 8216421 YP_003077760.1 CDS mppA NC_013008.1 1868576 1870189 D murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) ABC transporter periplasmic-binding protein 1868576..1870189 Escherichia coli O157:H7 str. TW14359 8216422 YP_003077761.1 CDS ynaI NC_013008.1 1870240 1871271 R hypothetical protein complement(1870240..1871271) Escherichia coli O157:H7 str. TW14359 8216423 YP_003077762.1 CDS ynaJ NC_013008.1 1871515 1871772 D inner membrane protein 1871515..1871772 Escherichia coli O157:H7 str. TW14359 8216424 YP_003077763.1 CDS ECSP_1859 NC_013008.1 1871822 1872772 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1871822..1872772) Escherichia coli O157:H7 str. TW14359 8216425 YP_003077764.1 CDS fnr NC_013008.1 1872924 1873676 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1872924..1873676) Escherichia coli O157:H7 str. TW14359 8216426 YP_003077765.1 CDS ogt NC_013008.1 1873871 1874386 R O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1873871..1874386) Escherichia coli O157:H7 str. TW14359 8216427 YP_003077766.1 CDS abgT NC_013008.1 1874397 1875923 R aminobenzoyl-glutamate transporter complement(1874397..1875923) Escherichia coli O157:H7 str. TW14359 8216428 YP_003077767.1 CDS abgB NC_013008.1 1875960 1877405 R peptidase complement(1875960..1877405) Escherichia coli O157:H7 str. TW14359 8216429 YP_003077768.1 CDS abgA NC_013008.1 1877405 1878715 R peptidase complement(1877405..1878715) Escherichia coli O157:H7 str. TW14359 8216430 YP_003077769.1 CDS abgR NC_013008.1 1878891 1879799 D DNA-binding transcriptional regulator 1878891..1879799 Escherichia coli O157:H7 str. TW14359 8216431 YP_003077770.1 CDS ydaL NC_013008.1 1880129 1880692 D hypothetical protein 1880129..1880692 Escherichia coli O157:H7 str. TW14359 8216432 YP_003077771.1 CDS ydaM NC_013008.1 1880713 1881945 R diguanylate cyclase, GGDEF domain signalling protein complement(1880713..1881945) Escherichia coli O157:H7 str. TW14359 8216433 YP_003077772.1 CDS zntB NC_013008.1 1882200 1883183 D zinc transporter 1882200..1883183 Escherichia coli O157:H7 str. TW14359 8216434 YP_003077773.1 CDS ECSP_1869 NC_013008.1 1883252 1883356 R hypothetical protein complement(1883252..1883356) Escherichia coli O157:H7 str. TW14359 8216435 YP_003077774.1 CDS ECSP_1870 NC_013008.1 1883413 1883649 R hypothetical protein complement(1883413..1883649) Escherichia coli O157:H7 str. TW14359 8216436 YP_003077775.1 CDS dbpA NC_013008.1 1883661 1885034 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1883661..1885034 Escherichia coli O157:H7 str. TW14359 8216437 YP_003077776.1 CDS ttcA NC_013008.1 1885163 1886098 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1885163..1886098) Escherichia coli O157:H7 str. TW14359 8216438 YP_003077777.1 CDS uspF NC_013008.1 1886274 1886708 R stress-induced protein, ATP-binding protein complement(1886274..1886708) Escherichia coli O157:H7 str. TW14359 8216439 YP_003077778.1 CDS ydbK NC_013008.1 1888328 1891852 R fused pyruvate-flavodoxin oxidoreductase: conserved protein, conserved protein, FeS binding protein complement(1888328..1891852) Escherichia coli O157:H7 str. TW14359 8216441 YP_003077779.1 CDS ydbJ NC_013008.1 1892126 1892392 D hypothetical protein 1892126..1892392 Escherichia coli O157:H7 str. TW14359 8216442 YP_003077780.1 CDS hslJ NC_013008.1 1892389 1892811 R heat-inducible protein complement(1892389..1892811) Escherichia coli O157:H7 str. TW14359 8216443 YP_003077781.1 CDS ldhA NC_013008.1 1892922 1893911 R fermentative D-lactate dehydrogenase, NAD-dependent complement(1892922..1893911) Escherichia coli O157:H7 str. TW14359 8216444 YP_003077782.1 CDS ydbH NC_013008.1 1894119 1896758 D hypothetical protein 1894119..1896758 Escherichia coli O157:H7 str. TW14359 8216445 YP_003077783.1 CDS ynbE NC_013008.1 1896755 1896940 D lipoprotein 1896755..1896940 Escherichia coli O157:H7 str. TW14359 8216446 YP_003077784.1 CDS ydbL NC_013008.1 1896948 1897271 D hypothetical protein 1896948..1897271 Escherichia coli O157:H7 str. TW14359 8216447 YP_003077785.1 CDS ECSP_1882 NC_013008.1 1897685 1900720 D hypothetical protein 1897685..1900720 Escherichia coli O157:H7 str. TW14359 8216448 YP_003077786.1 CDS ECSP_1883 NC_013008.1 1900940 1903399 D autotransporter-1 (AT-1) family protein 1900940..1903399 Escherichia coli O157:H7 str. TW14359 8216449 YP_003077787.1 CDS ydbC NC_013008.1 1903619 1904479 D oxidoreductase 1903619..1904479 Escherichia coli O157:H7 str. TW14359 8216450 YP_003077788.1 CDS ydbD NC_013008.1 1904543 1906849 D hypothetical protein 1904543..1906849 Escherichia coli O157:H7 str. TW14359 8216451 YP_003077789.1 CDS ynbA NC_013008.1 1907020 1907625 D inner membrane protein 1907020..1907625 Escherichia coli O157:H7 str. TW14359 8216452 YP_003077790.1 CDS ynbB NC_013008.1 1907625 1908521 D CDP-diglyceride synthase 1907625..1908521 Escherichia coli O157:H7 str. TW14359 8216453 YP_003077791.1 CDS ynbC NC_013008.1 1908537 1910294 D hydrolase 1908537..1910294 Escherichia coli O157:H7 str. TW14359 8216454 YP_003077792.1 CDS ynbD NC_013008.1 1910308 1911600 D phosphatase, inner membrane protein 1910308..1911600 Escherichia coli O157:H7 str. TW14359 8216455 YP_003077793.1 CDS azoR NC_013008.1 1911651 1912256 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1911651..1912256) Escherichia coli O157:H7 str. TW14359 8216456 YP_003077794.1 CDS hrpA NC_013008.1 1912457 1916359 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1912457..1916359 Escherichia coli O157:H7 str. TW14359 8216457 YP_003077795.1 CDS ECSP_1892 NC_013008.1 1916505 1916930 D hypothetical protein 1916505..1916930 Escherichia coli O157:H7 str. TW14359 8216458 YP_003077796.1 CDS ECSP_1893 NC_013008.1 1916935 1917273 D hypothetical protein 1916935..1917273 Escherichia coli O157:H7 str. TW14359 8216459 YP_003077797.1 CDS ECSP_1894 NC_013008.1 1917260 1917691 D hypothetical protein 1917260..1917691 Escherichia coli O157:H7 str. TW14359 8216460 YP_003077798.1 CDS ECSP_1895 NC_013008.1 1917816 1918193 D hypothetical protein 1917816..1918193 Escherichia coli O157:H7 str. TW14359 8216461 YP_003077799.1 CDS ydcF NC_013008.1 1918309 1919109 D hypothetical protein 1918309..1919109 Escherichia coli O157:H7 str. TW14359 8216462 YP_003077800.1 CDS aldA NC_013008.1 1919306 1920745 D NAD-linked; aldehyde dehydrogenase 1919306..1920745 Escherichia coli O157:H7 str. TW14359 8216463 YP_003077801.1 CDS gapC NC_013008.1 1920787 1921788 R glyceraldehyde-3-phosphate dehydrogenase complement(1920787..1921788) Escherichia coli O157:H7 str. TW14359 8216464 YP_003077802.1 CDS cybB NC_013008.1 1921977 1922507 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1921977..1922507 Escherichia coli O157:H7 str. TW14359 8216465 YP_003077803.1 CDS ydcA NC_013008.1 1922752 1922925 D hypothetical protein 1922752..1922925 Escherichia coli O157:H7 str. TW14359 8216466 YP_003077804.1 CDS mokB NC_013008.1 1923037 1923204 R regulatory peptide complement(1923037..1923204) Escherichia coli O157:H7 str. TW14359 8216467 YP_003077805.1 CDS trg NC_013008.1 1923545 1925185 D methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1923545..1925185 Escherichia coli O157:H7 str. TW14359 8216468 YP_003077806.1 CDS ydcI NC_013008.1 1925223 1926146 R DNA-binding transcriptional regulator complement(1925223..1926146) Escherichia coli O157:H7 str. TW14359 8216469 YP_003077807.1 CDS ydcJ NC_013008.1 1927182 1927706 D hypothetical protein 1927182..1927706 Escherichia coli O157:H7 str. TW14359 8216470 YP_003077808.1 CDS mdoD NC_013008.1 1927931 1929586 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1927931..1929586 Escherichia coli O157:H7 str. TW14359 8216471 YP_003077809.1 CDS ydcH NC_013008.1 1929726 1929950 D hypothetical protein 1929726..1929950 Escherichia coli O157:H7 str. TW14359 8216472 YP_003077810.1 CDS ydcK NC_013008.1 1930544 1931524 R hypothetical protein complement(1930544..1931524) Escherichia coli O157:H7 str. TW14359 8216474 YP_003077811.1 CDS tehA NC_013008.1 1931648 1932640 D potassium-tellurite ethidium and proflavin transporter 1931648..1932640 Escherichia coli O157:H7 str. TW14359 8216475 YP_003077812.1 CDS tehB NC_013008.1 1932637 1933230 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1932637..1933230 Escherichia coli O157:H7 str. TW14359 8216476 YP_003077813.1 CDS ydcL NC_013008.1 1933534 1934202 D lipoprotein 1933534..1934202 Escherichia coli O157:H7 str. TW14359 8216477 YP_003077814.1 CDS ydcN NC_013008.1 1935502 1936038 D DNA-binding transcriptional regulator 1935502..1936038 Escherichia coli O157:H7 str. TW14359 8216479 YP_003077815.1 CDS ydcP NC_013008.1 1936111 1938072 D peptidase 1936111..1938072 Escherichia coli O157:H7 str. TW14359 8216480 YP_003077816.1 CDS yncJ NC_013008.1 1938164 1938394 R hypothetical protein complement(1938164..1938394) Escherichia coli O157:H7 str. TW14359 8216481 YP_003077817.1 CDS ECSP_1916 NC_013008.1 1938451 1938573 R hypothetical protein complement(1938451..1938573) Escherichia coli O157:H7 str. TW14359 8216482 YP_003077818.1 CDS yncN NC_013008.1 1938616 1938792 D hypothetical protein 1938616..1938792 Escherichia coli O157:H7 str. TW14359 8216483 YP_003077819.1 CDS ydcQ NC_013008.1 1938817 1939254 D DNA-binding transcriptional regulator 1938817..1939254 Escherichia coli O157:H7 str. TW14359 8216484 YP_003077820.1 CDS ydcR NC_013008.1 1939333 1940739 D DNA-binding transcriptional regulator with an aminotransferase domain 1939333..1940739 Escherichia coli O157:H7 str. TW14359 8216485 YP_003077821.1 CDS ydcS NC_013008.1 1940984 1942129 D spermidine/putrescine ABC transporter periplasmic-binding protein 1940984..1942129 Escherichia coli O157:H7 str. TW14359 8216486 YP_003077822.1 CDS ydcT NC_013008.1 1942147 1943160 D spermidine/putrescine ABC transporter ATP-binding protein 1942147..1943160 Escherichia coli O157:H7 str. TW14359 8216487 YP_003077823.1 CDS ydcU NC_013008.1 1943161 1944102 D spermidine/putrescine ABC transporter membrane protein 1943161..1944102 Escherichia coli O157:H7 str. TW14359 8216488 YP_003077824.1 CDS ydcV NC_013008.1 1944092 1944886 D spermidine/putrescine ABC transporter membrane protein 1944092..1944886 Escherichia coli O157:H7 str. TW14359 8216489 YP_003077825.1 CDS ydcW NC_013008.1 1944908 1946332 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1944908..1946332 Escherichia coli O157:H7 str. TW14359 8216490 YP_003077826.1 CDS ECSP_1925 NC_013008.1 1946329 1946445 R hypothetical protein complement(1946329..1946445) Escherichia coli O157:H7 str. TW14359 8216491 YP_003077827.1 CDS ydcX NC_013008.1 1946719 1946892 D inner membrane protein 1946719..1946892 Escherichia coli O157:H7 str. TW14359 8216492 YP_003077828.1 CDS ydcY NC_013008.1 1946978 1947211 D hypothetical protein 1946978..1947211 Escherichia coli O157:H7 str. TW14359 8216493 YP_003077829.1 CDS ydcZ NC_013008.1 1947212 1947661 R inner membrane protein complement(1947212..1947661) Escherichia coli O157:H7 str. TW14359 8216494 YP_003077830.1 CDS yncA NC_013008.1 1947658 1948176 R acyl-CoA N-acyltransferase domain-containing acyltransferase complement(1947658..1948176) Escherichia coli O157:H7 str. TW14359 8216495 YP_003077831.1 CDS yncB NC_013008.1 1948357 1949394 D oxidoreductase 1948357..1949394 Escherichia coli O157:H7 str. TW14359 8216496 YP_003077832.1 CDS yncC NC_013008.1 1949592 1950257 D DNA-binding transcriptional regulator 1949592..1950257 Escherichia coli O157:H7 str. TW14359 8216497 YP_003077833.1 CDS yncD NC_013008.1 1950293 1952395 R iron outer membrane transporter complement(1950293..1952395) Escherichia coli O157:H7 str. TW14359 8216498 YP_003077834.1 CDS yncE NC_013008.1 1952637 1953698 D hypothetical protein 1952637..1953698 Escherichia coli O157:H7 str. TW14359 8216499 YP_003077835.1 CDS ansP NC_013008.1 1953813 1955312 R L-asparagine transporter complement(1953813..1955312) Escherichia coli O157:H7 str. TW14359 8216500 YP_003077836.1 CDS yncG NC_013008.1 1955579 1956196 D hypothetical protein 1955579..1956196 Escherichia coli O157:H7 str. TW14359 8216501 YP_003077837.1 CDS yncH NC_013008.1 1956272 1956484 D hypothetical protein 1956272..1956484 Escherichia coli O157:H7 str. TW14359 8216502 YP_003077838.1 CDS ECSP_1937 NC_013008.1 1956897 1957043 R hypothetical protein complement(1956897..1957043) Escherichia coli O157:H7 str. TW14359 8216503 YP_003077839.1 CDS vgrE NC_013008.1 1957269 1959413 D hypothetical protein 1957269..1959413 Escherichia coli O157:H7 str. TW14359 8216504 YP_003077840.1 CDS ECSP_1939 NC_013008.1 1961712 1963682 D hypothetical protein 1961712..1963682 Escherichia coli O157:H7 str. TW14359 8216505 YP_003077841.1 CDS ECSP_1940 NC_013008.1 1963879 1964088 D hypothetical protein 1963879..1964088 Escherichia coli O157:H7 str. TW14359 8216506 YP_003077842.1 CDS ECSP_1941 NC_013008.1 1964155 1964304 D hypothetical protein 1964155..1964304 Escherichia coli O157:H7 str. TW14359 8216507 YP_003077843.1 CDS ECSP_1942 NC_013008.1 1964596 1964775 D partial H repeat-associated protein of Rhs element 1964596..1964775 Escherichia coli O157:H7 str. TW14359 8216508 YP_003077844.1 CDS ECSP_1943 NC_013008.1 1964875 1965765 D transposase 1964875..1965765 Escherichia coli O157:H7 str. TW14359 8216509 YP_003077845.1 CDS ydcE NC_013008.1 1965864 1966091 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1965864..1966091 Escherichia coli O157:H7 str. TW14359 8216510 YP_003077846.1 CDS yddH NC_013008.1 1966095 1966538 R hypothetical protein complement(1966095..1966538) Escherichia coli O157:H7 str. TW14359 8216511 YP_003077847.1 CDS ECSP_1946 NC_013008.1 1966542 1966712 R hypothetical protein complement(1966542..1966712) Escherichia coli O157:H7 str. TW14359 8216512 YP_003077848.1 CDS yddE NC_013008.1 1967777 1968670 R hypothetical protein complement(1967777..1968670) Escherichia coli O157:H7 str. TW14359 8216514 YP_003077849.1 CDS narV NC_013008.1 1968749 1969429 R nitrate reductase 2 (NRZ) subunit gamma complement(1968749..1969429) Escherichia coli O157:H7 str. TW14359 8216515 YP_003077850.1 CDS narW NC_013008.1 1969426 1970121 R nitrate reductase 2 (NRZ) subunit delta complement(1969426..1970121) Escherichia coli O157:H7 str. TW14359 8216516 YP_003077851.1 CDS narY NC_013008.1 1970121 1971665 R nitrate reductase 2 (NRZ) subunit beta complement(1970121..1971665) Escherichia coli O157:H7 str. TW14359 8216517 YP_003077852.1 CDS narZ NC_013008.1 1971662 1975402 R nitrate reductase 2 (NRZ) subunit alpha complement(1971662..1975402) Escherichia coli O157:H7 str. TW14359 8216518 YP_003077853.1 CDS narU NC_013008.1 1975484 1976872 R nitrate/nitrite transporter complement(1975484..1976872) Escherichia coli O157:H7 str. TW14359 8216519 YP_003077854.1 CDS espR1 NC_013008.1 1977178 1978437 R non-LEE-encoded type III effector complement(1977178..1978437) Escherichia coli O157:H7 str. TW14359 8216520 YP_003077855.1 CDS ECSP_1955 NC_013008.1 1978500 1979168 R hypothetical protein complement(1978500..1979168) Escherichia coli O157:H7 str. TW14359 8216521 YP_003077856.1 CDS ECSP_1956 NC_013008.1 1979927 1981027 R outer membrane porin protein complement(1979927..1981027) Escherichia coli O157:H7 str. TW14359 8216522 YP_003077857.1 CDS yddG NC_013008.1 1981286 1982167 R hypothetical protein complement(1981286..1982167) Escherichia coli O157:H7 str. TW14359 8216523 YP_003077858.1 CDS fdnH NC_013008.1 1985459 1986343 D formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible 1985459..1986343 Escherichia coli O157:H7 str. TW14359 8216525 YP_003077859.1 CDS fdnI NC_013008.1 1986336 1986989 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1986336..1986989 Escherichia coli O157:H7 str. TW14359 8216526 YP_003077860.1 CDS yddM NC_013008.1 1987217 1987501 R DNA-binding transcriptional regulator complement(1987217..1987501) Escherichia coli O157:H7 str. TW14359 8216527 YP_003077861.1 CDS adhP NC_013008.1 1987647 1988657 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1987647..1988657) Escherichia coli O157:H7 str. TW14359 8216528 YP_003077862.1 CDS sfcA NC_013008.1 1988791 1990488 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1988791..1990488) Escherichia coli O157:H7 str. TW14359 8216529 YP_003077863.1 CDS rpsV NC_013008.1 1990645 1990782 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1990645..1990782) Escherichia coli O157:H7 str. TW14359 8216530 YP_003077864.1 CDS bdm NC_013008.1 1990884 1991099 R biofilm-dependent modulation protein complement(1990884..1991099) Escherichia coli O157:H7 str. TW14359 8216531 YP_003077865.1 CDS ECSP_1966 NC_013008.1 1991266 1991406 D hypothetical protein 1991266..1991406 Escherichia coli O157:H7 str. TW14359 8216532 YP_003077866.1 CDS osmC NC_013008.1 1991444 1991875 D osmotically inducible, stress-inducible membrane protein 1991444..1991875 Escherichia coli O157:H7 str. TW14359 8216533 YP_003077867.1 CDS ddpF NC_013008.1 1991931 1992857 R D-ala-D-ala ABC transporter ATP-binding protein complement(1991931..1992857) Escherichia coli O157:H7 str. TW14359 8216534 YP_003077868.1 CDS ddpD NC_013008.1 1992850 1993836 R D-ala-D-ala ABC transporter ATP-binding protein complement(1992850..1993836) Escherichia coli O157:H7 str. TW14359 8216535 YP_003077869.1 CDS ddpC NC_013008.1 1993833 1994729 R ATP-dependent peptide transporter membrane subunit complement(1993833..1994729) Escherichia coli O157:H7 str. TW14359 8216536 YP_003077870.1 CDS ddpB NC_013008.1 1994726 1995706 R D-ala-D-ala ABC transporter membrane protein complement(1994726..1995706) Escherichia coli O157:H7 str. TW14359 8216537 YP_003077871.1 CDS ddpA NC_013008.1 1995750 1997300 R D-ala-D-ala ABC transporter periplasmic-binding protein complement(1995750..1997300) Escherichia coli O157:H7 str. TW14359 8216538 YP_003077872.1 CDS ddpX NC_013008.1 1997314 1997895 R catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase complement(1997314..1997895) Escherichia coli O157:H7 str. TW14359 8216539 YP_003077873.1 CDS yddV NC_013008.1 2000567 2001949 R diguanylate cyclase complement(2000567..2001949) Escherichia coli O157:H7 str. TW14359 8216541 YP_003077874.1 CDS yddW NC_013008.1 2002326 2003645 R lipoprotein complement(2002326..2003645) Escherichia coli O157:H7 str. TW14359 8216542 YP_003077875.1 CDS gadC NC_013008.1 2003776 2005311 R glutamate:gamma-aminobutyric acid antiporter complement(2003776..2005311) Escherichia coli O157:H7 str. TW14359 8216543 YP_003077876.1 CDS gadB NC_013008.1 2005467 2006867 R glutamate decarboxylase B, PLP-dependent complement(2005467..2006867) Escherichia coli O157:H7 str. TW14359 8216544 YP_003077877.1 CDS pqqL NC_013008.1 2007228 2010023 R peptidase complement(2007228..2010023) Escherichia coli O157:H7 str. TW14359 8216545 YP_003077878.1 CDS yddB NC_013008.1 2010068 2012440 R porin protein complement(2010068..2012440) Escherichia coli O157:H7 str. TW14359 8216546 YP_003077879.1 CDS yddA NC_013008.1 2012478 2014163 R fused multidrug transporter subunits of ABC superfamily: membrane component, ATP-binding protein complement(2012478..2014163) Escherichia coli O157:H7 str. TW14359 8216547 YP_003077880.1 CDS ydeM NC_013008.1 2014454 2015611 R hypothetical protein complement(2014454..2015611) Escherichia coli O157:H7 str. TW14359 8216548 YP_003077881.1 CDS ECSP_1983 NC_013008.1 2015663 2015770 R hypothetical protein complement(2015663..2015770) Escherichia coli O157:H7 str. TW14359 8216549 YP_003077882.1 CDS ydeN NC_013008.1 2015873 2017345 R hypothetical protein complement(2015873..2017345) Escherichia coli O157:H7 str. TW14359 8216550 YP_003077883.1 CDS ydeO NC_013008.1 2017749 2018510 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(2017749..2018510) Escherichia coli O157:H7 str. TW14359 8216551 YP_003077884.1 CDS ydeP NC_013008.1 2019029 2021308 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase complement(2019029..2021308) Escherichia coli O157:H7 str. TW14359 8216552 YP_003077885.1 CDS fmlD NC_013008.1 2021642 2022556 R F9 fimbriae adhesin complement(2021642..2022556) Escherichia coli O157:H7 str. TW14359 8216553 YP_003077886.1 CDS ydeR NC_013008.1 2022616 2023119 R F9 fimbriae protein complement(2022616..2023119) Escherichia coli O157:H7 str. TW14359 8216554 YP_003077887.1 CDS ydeS NC_013008.1 2023132 2023662 R F9 fimbriae protein complement(2023132..2023662) Escherichia coli O157:H7 str. TW14359 8216555 YP_003077888.1 CDS fmlC NC_013008.1 2023676 2026327 R F9 fimbriae usher protein complement(2023676..2026327) Escherichia coli O157:H7 str. TW14359 8216556 YP_003077889.1 CDS fmlB NC_013008.1 2026369 2027079 R F9 fimbriae chaperone complement(2026369..2027079) Escherichia coli O157:H7 str. TW14359 8216557 YP_003077890.1 CDS fmlA NC_013008.1 2027440 2028003 R major subunit of F9 fimbriae complement(2027440..2028003) Escherichia coli O157:H7 str. TW14359 8216558 YP_003077891.1 CDS yneL NC_013008.1 2028437 2028640 R transcriptional regulator complement(2028437..2028640) Escherichia coli O157:H7 str. TW14359 8216559 YP_003077892.1 CDS hipA NC_013008.1 2028977 2029999 R regulator with hipB complement(2028977..2029999) Escherichia coli O157:H7 str. TW14359 8216560 YP_003077893.1 CDS ydeK NC_013008.1 2031554 2035585 R lipoprotein complement(2031554..2035585) Escherichia coli O157:H7 str. TW14359 8216561 YP_003077894.1 CDS lsrK NC_013008.1 2036116 2037708 R autoinducer-2 (AI-2) kinase complement(2036116..2037708) Escherichia coli O157:H7 str. TW14359 8216562 YP_003077895.1 CDS lsrR NC_013008.1 2037787 2038740 R lsr operon transcriptional repressor complement(2037787..2038740) Escherichia coli O157:H7 str. TW14359 8216563 YP_003077896.1 CDS lsrA NC_013008.1 2038989 2040524 D fused AI2 transporter subunits of ABC superfamily: ATP-binding proteins 2038989..2040524 Escherichia coli O157:H7 str. TW14359 8216564 YP_003077897.1 CDS lsrC NC_013008.1 2040518 2041546 D AI2 transporter, membrane component of ABC superfamily 2040518..2041546 Escherichia coli O157:H7 str. TW14359 8216565 YP_003077898.1 CDS lsrD NC_013008.1 2041546 2042538 D AI2 transporter, membrane component of ABC superfamily 2041546..2042538 Escherichia coli O157:H7 str. TW14359 8216566 YP_003077899.1 CDS lsrB NC_013008.1 2042550 2043572 D AI2 transporter, periplasmic-binding component of ABC superfamily 2042550..2043572 Escherichia coli O157:H7 str. TW14359 8216567 YP_003077900.1 CDS lsrF NC_013008.1 2043599 2044474 D aldolase 2043599..2044474 Escherichia coli O157:H7 str. TW14359 8216568 YP_003077901.1 CDS lsrG NC_013008.1 2044498 2044788 D autoinducer-2 (AI-2) modifying protein LsrG 2044498..2044788 Escherichia coli O157:H7 str. TW14359 8216569 YP_003077902.1 CDS tam NC_013008.1 2044845 2045603 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 2044845..2045603 Escherichia coli O157:H7 str. TW14359 8216570 YP_003077903.1 CDS yneE NC_013008.1 2045607 2046521 R hypothetical protein complement(2045607..2046521) Escherichia coli O157:H7 str. TW14359 8216571 YP_003077904.1 CDS uxaB NC_013008.1 2046718 2048169 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(2046718..2048169) Escherichia coli O157:H7 str. TW14359 8216572 YP_003077905.1 CDS yneF NC_013008.1 2048396 2049343 R diguanylate cyclase complement(2048396..2049343) Escherichia coli O157:H7 str. TW14359 8216573 YP_003077906.1 CDS yneG NC_013008.1 2049953 2050312 R hypothetical protein complement(2049953..2050312) Escherichia coli O157:H7 str. TW14359 8216574 YP_003077907.1 CDS yneH NC_013008.1 2050312 2051238 R catalyzes the formation of glutamate from glutamine; glutaminase complement(2050312..2051238) Escherichia coli O157:H7 str. TW14359 8216575 YP_003077908.1 CDS yneI NC_013008.1 2051302 2052690 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(2051302..2052690) Escherichia coli O157:H7 str. TW14359 8216576 YP_003077909.1 CDS yneJ NC_013008.1 2052791 2053672 D DNA-binding transcriptional regulator 2052791..2053672 Escherichia coli O157:H7 str. TW14359 8216577 YP_003077910.1 CDS ydeA NC_013008.1 2055016 2056206 D sugar efflux transporter 2055016..2056206 Escherichia coli O157:H7 str. TW14359 8216579 YP_003077911.1 CDS marC NC_013008.1 2056231 2056896 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(2056231..2056896) Escherichia coli O157:H7 str. TW14359 8216580 YP_003077912.1 CDS marR NC_013008.1 2057108 2057542 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 2057108..2057542 Escherichia coli O157:H7 str. TW14359 8216581 YP_003077913.1 CDS marA NC_013008.1 2057562 2057945 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 2057562..2057945 Escherichia coli O157:H7 str. TW14359 8216582 YP_003077914.1 CDS marB NC_013008.1 2057977 2058195 D hypothetical protein 2057977..2058195 Escherichia coli O157:H7 str. TW14359 8216583 YP_003077915.1 CDS ydeD NC_013008.1 2058226 2059125 R O-acetylserine/cysteine export protein complement(2058226..2059125) Escherichia coli O157:H7 str. TW14359 8216584 YP_003077916.1 CDS ydeE NC_013008.1 2059320 2060507 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 2059320..2060507 Escherichia coli O157:H7 str. TW14359 8216585 YP_003077917.1 CDS ECSP_2020 NC_013008.1 2060548 2060943 R hypothetical protein complement(2060548..2060943) Escherichia coli O157:H7 str. TW14359 8216586 YP_003077918.1 CDS ftrA NC_013008.1 2061026 2062009 D upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrA 2061026..2062009 Escherichia coli O157:H7 str. TW14359 8216587 YP_003077919.1 CDS ydeH NC_013008.1 2062431 2063321 R hypothetical protein complement(2062431..2063321) Escherichia coli O157:H7 str. TW14359 8216588 YP_003077920.1 CDS ydeI NC_013008.1 2063576 2063968 R hypothetical protein complement(2063576..2063968) Escherichia coli O157:H7 str. TW14359 8216589 YP_003077921.1 CDS ydeJ NC_013008.1 2064244 2064762 D competence damage-inducible protein A 2064244..2064762 Escherichia coli O157:H7 str. TW14359 8216590 YP_003077922.1 CDS dcp NC_013008.1 2064807 2066852 R dipeptidyl carboxypeptidase II complement(2064807..2066852) Escherichia coli O157:H7 str. TW14359 8216591 YP_003077923.1 CDS ydfG NC_013008.1 2066989 2067735 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 2066989..2067735 Escherichia coli O157:H7 str. TW14359 8216592 YP_003077924.1 CDS ydfH NC_013008.1 2067824 2068510 D DNA-binding transcriptional regulator 2067824..2068510 Escherichia coli O157:H7 str. TW14359 8216593 YP_003077925.1 CDS ydfZ NC_013008.1 2068687 2068890 D hypothetical protein 2068687..2068890 Escherichia coli O157:H7 str. TW14359 8216594 YP_003077926.1 CDS ydfI NC_013008.1 2068926 2070386 R mannonate dehydrogenase complement(2068926..2070386) Escherichia coli O157:H7 str. TW14359 8216595 YP_003077927.1 CDS ydfJ NC_013008.1 2070475 2071758 R transporter complement(2070475..2071758) Escherichia coli O157:H7 str. TW14359 8216596 YP_003077928.1 CDS ECSP_2031 NC_013008.1 2072294 2072935 R non-LEE-encoded type III effector complement(2072294..2072935) Escherichia coli O157:H7 str. TW14359 8216597 YP_003077929.1 CDS ECSP_2032 NC_013008.1 2073017 2073646 R non-LEE-encoded type III effector complement(2073017..2073646) Escherichia coli O157:H7 str. TW14359 8216598 YP_003077930.1 CDS ECSP_2033 NC_013008.1 2073719 2074294 R non-LEE-encoded type III effector complement(2073719..2074294) Escherichia coli O157:H7 str. TW14359 8216599 YP_003077931.1 CDS ECSP_2034 NC_013008.1 2074408 2074677 R hypothetical protein complement(2074408..2074677) Escherichia coli O157:H7 str. TW14359 8216600 YP_003077932.1 CDS ECSP_2035 NC_013008.1 2074679 2075992 R hypothetical protein complement(2074679..2075992) Escherichia coli O157:H7 str. TW14359 8216601 YP_003077933.1 CDS ECSP_2036 NC_013008.1 2076057 2076656 R Ail/Lom family protein complement(2076057..2076656) Escherichia coli O157:H7 str. TW14359 8216602 YP_003077934.1 CDS ECSP_2037 NC_013008.1 2076724 2079237 R host specificity protein complement(2076724..2079237) Escherichia coli O157:H7 str. TW14359 8216603 YP_003077935.1 CDS ECSP_2038 NC_013008.1 2079234 2080802 R host specificity protein complement(2079234..2080802) Escherichia coli O157:H7 str. TW14359 8216604 YP_003077936.1 CDS ECSP_2039 NC_013008.1 2081144 2081725 R tail assembly protein complement(2081144..2081725) Escherichia coli O157:H7 str. TW14359 8216605 YP_003077937.1 CDS ECSP_2040 NC_013008.1 2081722 2082465 R tail assembly protein complement(2081722..2082465) Escherichia coli O157:H7 str. TW14359 8216606 YP_003077938.1 CDS ECSP_2041 NC_013008.1 2082476 2083174 R phage minor tail protein L complement(2082476..2083174) Escherichia coli O157:H7 str. TW14359 8216607 YP_003077939.1 CDS ECSP_2042 NC_013008.1 2083174 2083515 R minor tail protein complement(2083174..2083515) Escherichia coli O157:H7 str. TW14359 8216608 YP_003077940.1 CDS ECSP_2043 NC_013008.1 2083508 2086750 R tail length tape measure protein complement(2083508..2086750) Escherichia coli O157:H7 str. TW14359 8216609 YP_003077941.1 CDS ECSP_2044 NC_013008.1 2086802 2087005 R hypothetical protein complement(2086802..2087005) Escherichia coli O157:H7 str. TW14359 8216610 YP_003077942.1 CDS ECSP_2045 NC_013008.1 2087107 2087481 R tail assembly chaperone complement(2087107..2087481) Escherichia coli O157:H7 str. TW14359 8216611 YP_003077943.1 CDS ECSP_2046 NC_013008.1 2087487 2088203 R major tail subunit complement(2087487..2088203) Escherichia coli O157:H7 str. TW14359 8216612 YP_003077944.1 CDS ECSP_2047 NC_013008.1 2088262 2088606 R hypothetical protein complement(2088262..2088606) Escherichia coli O157:H7 str. TW14359 8216613 YP_003077945.1 CDS ECSP_2048 NC_013008.1 2088603 2089049 R hypothetical protein complement(2088603..2089049) Escherichia coli O157:H7 str. TW14359 8216614 YP_003077946.1 CDS ECSP_2049 NC_013008.1 2089046 2089396 R head-tail adaptor complement(2089046..2089396) Escherichia coli O157:H7 str. TW14359 8216615 YP_003077947.1 CDS ECSP_2050 NC_013008.1 2089406 2089732 R hypothetical protein complement(2089406..2089732) Escherichia coli O157:H7 str. TW14359 8216616 YP_003077948.1 CDS ECSP_2051 NC_013008.1 2089729 2090466 R portal protein complement(2089729..2090466) Escherichia coli O157:H7 str. TW14359 8216617 YP_003077949.1 CDS ECSP_2052 NC_013008.1 2090463 2091767 R portal protein complement(2090463..2091767) Escherichia coli O157:H7 str. TW14359 8216618 YP_003077950.1 CDS ECSP_2053 NC_013008.1 2092039 2092536 R major head protein/prohead protease complement(2092039..2092536) Escherichia coli O157:H7 str. TW14359 8216619 YP_003077951.1 CDS ECSP_2054 NC_013008.1 2092538 2092945 R hypothetical protein complement(2092538..2092945) Escherichia coli O157:H7 str. TW14359 8216620 YP_003077952.1 CDS ECSP_2055 NC_013008.1 2092950 2093156 R hypothetical protein complement(2092950..2093156) Escherichia coli O157:H7 str. TW14359 8216621 YP_003077953.1 CDS ECSP_2056 NC_013008.1 2093604 2095454 R hypothetical protein complement(2093604..2095454) Escherichia coli O157:H7 str. TW14359 8216622 YP_003077954.1 CDS ECSP_2057 NC_013008.1 2095932 2096426 R hypothetical protein complement(2095932..2096426) Escherichia coli O157:H7 str. TW14359 8216623 YP_003077955.1 CDS ECSP_2060 NC_013008.1 2096814 2097527 R AraC family transcriptional regulator complement(2096814..2097527) Escherichia coli O157:H7 str. TW14359 8216626 YP_003077956.1 CDS ECSP_2061 NC_013008.1 2097663 2097947 R hypothetical protein complement(2097663..2097947) Escherichia coli O157:H7 str. TW14359 8216627 YP_003077957.1 CDS ECSP_2062 NC_013008.1 2098085 2098639 R hypothetical protein complement(2098085..2098639) Escherichia coli O157:H7 str. TW14359 8216628 YP_003077958.1 CDS ECSP_2063 NC_013008.1 2098702 2099007 R endonuclease encoded within prophage CP-933O complement(2098702..2099007) Escherichia coli O157:H7 str. TW14359 8216629 YP_003077959.1 CDS ECSP_2064 NC_013008.1 2099020 2100069 R hypothetical protein complement(2099020..2100069) Escherichia coli O157:H7 str. TW14359 8216630 YP_003077960.1 CDS ECSP_2065 NC_013008.1 2100071 2100343 R hypothetical protein complement(2100071..2100343) Escherichia coli O157:H7 str. TW14359 8216631 YP_003077961.1 CDS ECSP_2066 NC_013008.1 2100465 2100809 R hypothetical protein complement(2100465..2100809) Escherichia coli O157:H7 str. TW14359 8216632 YP_003077962.1 CDS ECSP_2067 NC_013008.1 2101375 2101932 R hypothetical protein complement(2101375..2101932) Escherichia coli O157:H7 str. TW14359 8216633 YP_003077963.1 CDS ECSP_2068 NC_013008.1 2102280 2102591 R hypothetical protein complement(2102280..2102591) Escherichia coli O157:H7 str. TW14359 8216634 YP_003077964.1 CDS ECSP_2069 NC_013008.1 2103122 2103838 R hypothetical protein complement(2103122..2103838) Escherichia coli O157:H7 str. TW14359 8216635 YP_003077965.1 CDS ECSP_2070 NC_013008.1 2103872 2104333 R hypothetical protein complement(2103872..2104333) Escherichia coli O157:H7 str. TW14359 8216636 YP_003077966.1 CDS ECSP_2071 NC_013008.1 2104326 2105369 R hypothetical protein complement(2104326..2105369) Escherichia coli O157:H7 str. TW14359 8216637 YP_003077967.1 CDS ECSP_2072 NC_013008.1 2105438 2105863 R hypothetical protein complement(2105438..2105863) Escherichia coli O157:H7 str. TW14359 8216638 YP_003077968.1 CDS ECSP_2073 NC_013008.1 2105847 2106089 R hypothetical protein complement(2105847..2106089) Escherichia coli O157:H7 str. TW14359 8216639 YP_003077969.1 CDS ECSP_2074 NC_013008.1 2106181 2106819 D repressor protein encoded within prophage CP-933O 2106181..2106819 Escherichia coli O157:H7 str. TW14359 8216640 YP_003077970.1 CDS ECSP_2075 NC_013008.1 2107031 2107264 D hypothetical protein 2107031..2107264 Escherichia coli O157:H7 str. TW14359 8216641 YP_003077971.1 CDS ECSP_2076 NC_013008.1 2107276 2107914 D hypothetical protein 2107276..2107914 Escherichia coli O157:H7 str. TW14359 8216642 YP_003077972.1 CDS ECSP_2077 NC_013008.1 2107915 2108124 R hypothetical protein complement(2107915..2108124) Escherichia coli O157:H7 str. TW14359 8216643 YP_003077973.1 CDS ECSP_2078 NC_013008.1 2108173 2108433 R hypothetical protein complement(2108173..2108433) Escherichia coli O157:H7 str. TW14359 8216644 YP_003077974.1 CDS ECSP_2079 NC_013008.1 2108584 2108877 D similar to division inhibition protein DicB within CP-933O; division inhibition protein DicB-like protein within CP-933O 2108584..2108877 Escherichia coli O157:H7 str. TW14359 8216645 YP_003077975.1 CDS ECSP_2080 NC_013008.1 2109155 2110399 D exonuclease 2109155..2110399 Escherichia coli O157:H7 str. TW14359 8216646 YP_003077976.1 CDS ECSP_2081 NC_013008.1 2110510 2110932 D integrase 2110510..2110932 Escherichia coli O157:H7 str. TW14359 8216647 YP_003077977.1 CDS ECSP_2082 NC_013008.1 2111017 2111352 D hypothetical protein 2111017..2111352 Escherichia coli O157:H7 str. TW14359 8216648 YP_003077978.1 CDS ECSP_2084 NC_013008.1 2112294 2112695 D transposase 2112294..2112695 Escherichia coli O157:H7 str. TW14359 8216650 YP_003077979.1 CDS ECSP_2085 NC_013008.1 2112692 2113039 D transposase 2112692..2113039 Escherichia coli O157:H7 str. TW14359 8216651 YP_003077980.1 CDS ECSP_2086 NC_013008.1 2113089 2114627 D transposase ISEc8 2113089..2114627 Escherichia coli O157:H7 str. TW14359 8216652 YP_003077981.1 CDS ECSP_2087 NC_013008.1 2114638 2115060 R transposase within CP-933O complement(2114638..2115060) Escherichia coli O157:H7 str. TW14359 8216653 YP_003077982.1 CDS nleG7 NC_013008.1 2115210 2115860 R non-LEE-encoded type III effector complement(2115210..2115860) Escherichia coli O157:H7 str. TW14359 8216654 YP_003077983.1 CDS ECSP_2089 NC_013008.1 2116571 2117146 R hypothetical protein complement(2116571..2117146) Escherichia coli O157:H7 str. TW14359 8216655 YP_003077984.1 CDS ECSP_2090 NC_013008.1 2117260 2117529 R hypothetical protein complement(2117260..2117529) Escherichia coli O157:H7 str. TW14359 8216656 YP_003077985.1 CDS ECSP_2091 NC_013008.1 2117531 2118754 R tail fiber protein complement(2117531..2118754) Escherichia coli O157:H7 str. TW14359 8216657 YP_003077986.1 CDS ECSP_2092 NC_013008.1 2118819 2119418 R Ail/Lom family protein complement(2118819..2119418) Escherichia coli O157:H7 str. TW14359 8216658 YP_003077987.1 CDS ECSP_2093 NC_013008.1 2119704 2122964 R tail component of prophage CP-933O complement(2119704..2122964) Escherichia coli O157:H7 str. TW14359 8216659 YP_003077988.1 CDS ECSP_2094 NC_013008.1 2123152 2123589 R minor tail protein complement(2123152..2123589) Escherichia coli O157:H7 str. TW14359 8216660 YP_003077989.1 CDS ECSP_2095 NC_013008.1 2123589 2123930 R minor tail protein complement(2123589..2123930) Escherichia coli O157:H7 str. TW14359 8216661 YP_003077990.1 CDS ECSP_2096 NC_013008.1 2123923 2127165 R tail component of cryptic prophage CP-933P complement(2123923..2127165) Escherichia coli O157:H7 str. TW14359 8216662 YP_003077991.1 CDS ECSP_2097 NC_013008.1 2127213 2127494 R tail assembly protein of cryptic prophage CP-933P complement(2127213..2127494) Escherichia coli O157:H7 str. TW14359 8216663 YP_003077992.1 CDS ECSP_2098 NC_013008.1 2127518 2127892 R tail assembly protein of cryptic prophage CP-933P complement(2127518..2127892) Escherichia coli O157:H7 str. TW14359 8216664 YP_003077993.1 CDS ECSP_2099 NC_013008.1 2127907 2128623 R tail component of cryptic prophage CP-933P complement(2127907..2128623) Escherichia coli O157:H7 str. TW14359 8216665 YP_003077994.1 CDS ECSP_2100 NC_013008.1 2128689 2129033 R structural component of cryptic prophage CP-933P complement(2128689..2129033) Escherichia coli O157:H7 str. TW14359 8216666 YP_003077995.1 CDS ECSP_2101 NC_013008.1 2129030 2129476 R hypothetical protein complement(2129030..2129476) Escherichia coli O157:H7 str. TW14359 8216667 YP_003077996.1 CDS ECSP_2102 NC_013008.1 2129473 2129823 R head-tail adaptor protein complement(2129473..2129823) Escherichia coli O157:H7 str. TW14359 8216668 YP_003077997.1 CDS ECSP_2103 NC_013008.1 2129833 2130159 R hypothetical protein complement(2129833..2130159) Escherichia coli O157:H7 str. TW14359 8216669 YP_003077998.1 CDS ECSP_2104 NC_013008.1 2130162 2132741 R hypothetical protein complement(2130162..2132741) Escherichia coli O157:H7 str. TW14359 8216670 YP_003077999.1 CDS ECSP_2105 NC_013008.1 2132953 2134890 R hypothetical protein complement(2132953..2134890) Escherichia coli O157:H7 str. TW14359 8216671 YP_003078000.1 CDS ECSP_2106 NC_013008.1 2134954 2136615 R terminase large subunit complement(2134954..2136615) Escherichia coli O157:H7 str. TW14359 8216672 YP_003078001.1 CDS ECSP_2107 NC_013008.1 2136612 2137175 R terminase subunit complement(2136612..2137175) Escherichia coli O157:H7 str. TW14359 8216673 YP_003078002.1 CDS ECSP_2108 NC_013008.1 2137467 2137832 R HNH endonuclease complement(2137467..2137832) Escherichia coli O157:H7 str. TW14359 8216674 YP_003078003.1 CDS ECSP_2109 NC_013008.1 2138464 2138931 R bacteriophage lysis protein complement(2138464..2138931) Escherichia coli O157:H7 str. TW14359 8216675 YP_003078004.1 CDS ECSP_2110 NC_013008.1 2139085 2139654 R antirepressor protein complement(2139085..2139654) Escherichia coli O157:H7 str. TW14359 8216676 YP_003078005.1 CDS ECSP_2111 NC_013008.1 2139925 2140458 R endolysin encoded by cryptic prophage CP-933P complement(2139925..2140458) Escherichia coli O157:H7 str. TW14359 8216677 YP_003078006.1 CDS ECSP_2112 NC_013008.1 2140509 2140853 R hypothetical protein complement(2140509..2140853) Escherichia coli O157:H7 str. TW14359 8216678 YP_003078007.1 CDS ECSP_2113 NC_013008.1 2140858 2141064 R holin protein encoded by cryptic prophage CP-933P complement(2140858..2141064) Escherichia coli O157:H7 str. TW14359 8216679 YP_003078008.1 CDS ECSP_2114 NC_013008.1 2141513 2143363 R hypothetical protein complement(2141513..2143363) Escherichia coli O157:H7 str. TW14359 8216680 YP_003078009.1 CDS ECSP_2115 NC_013008.1 2143412 2143540 R hypothetical protein complement(2143412..2143540) Escherichia coli O157:H7 str. TW14359 8216681 YP_003078010.1 CDS ECSP_2116 NC_013008.1 2143678 2143845 R hypothetical protein complement(2143678..2143845) Escherichia coli O157:H7 str. TW14359 8216682 YP_003078011.1 CDS ECSP_2117 NC_013008.1 2143842 2144270 R hypothetical protein complement(2143842..2144270) Escherichia coli O157:H7 str. TW14359 8216683 YP_003078012.1 CDS ECSP_2121 NC_013008.1 2144908 2145597 R Q antiterminator encoded by prophage CP-933P complement(2144908..2145597) Escherichia coli O157:H7 str. TW14359 8216687 YP_003078013.1 CDS ECSP_2122 NC_013008.1 2145594 2145953 R endonuclease encoded by cryptic prophage CP-933P complement(2145594..2145953) Escherichia coli O157:H7 str. TW14359 8216688 YP_003078014.1 CDS ECSP_2123 NC_013008.1 2145966 2147015 R hypothetical protein complement(2145966..2147015) Escherichia coli O157:H7 str. TW14359 8216689 YP_003078015.1 CDS ECSP_2124 NC_013008.1 2147017 2147295 R hypothetical protein complement(2147017..2147295) Escherichia coli O157:H7 str. TW14359 8216690 YP_003078016.1 CDS mokP NC_013008.1 2147463 2147675 R cell killing protein encoded within cryptic prophage CP-933P complement(2147463..2147675) Escherichia coli O157:H7 str. TW14359 8216691 YP_003078017.1 CDS ECSP_2126 NC_013008.1 2147864 2147968 R hypothetical protein complement(2147864..2147968) Escherichia coli O157:H7 str. TW14359 8216692 YP_003078018.1 CDS ECSP_2127 NC_013008.1 2148084 2148728 R hypothetical protein complement(2148084..2148728) Escherichia coli O157:H7 str. TW14359 8216693 YP_003078019.1 CDS renP NC_013008.1 2148725 2149120 R exclusion protein ren of cryptic prophage CP-933P complement(2148725..2149120) Escherichia coli O157:H7 str. TW14359 8216694 YP_003078020.1 CDS ECSP_2130 NC_013008.1 2149931 2150671 R replication protein complement(2149931..2150671) Escherichia coli O157:H7 str. TW14359 8216696 YP_003078021.1 CDS ECSP_2131 NC_013008.1 2150678 2151640 R hypothetical protein complement(2150678..2151640) Escherichia coli O157:H7 str. TW14359 8216697 YP_003078022.1 CDS ECSP_2132 NC_013008.1 2151663 2152088 R hypothetical protein complement(2151663..2152088) Escherichia coli O157:H7 str. TW14359 8216698 YP_003078023.1 CDS ECSP_2133 NC_013008.1 2152085 2152387 R hypothetical protein complement(2152085..2152387) Escherichia coli O157:H7 str. TW14359 8216699 YP_003078024.1 CDS ECSP_2134 NC_013008.1 2152422 2152856 D repressor protein encoded by cryptic prophage CP-933P 2152422..2152856 Escherichia coli O157:H7 str. TW14359 8216700 YP_003078025.1 CDS ECSP_2135 NC_013008.1 2153070 2153348 D plasmid stabilization system protein 2153070..2153348 Escherichia coli O157:H7 str. TW14359 8216701 YP_003078026.1 CDS ECSP_2136 NC_013008.1 2153644 2154000 D hypothetical protein 2153644..2154000 Escherichia coli O157:H7 str. TW14359 8216702 YP_003078027.1 CDS ECSP_2137 NC_013008.1 2154072 2154290 D hypothetical protein 2154072..2154290 Escherichia coli O157:H7 str. TW14359 8216703 YP_003078028.1 CDS ECSP_2138 NC_013008.1 2154754 2155047 D inhibitor of cell division encoded by cryptic prophage CP-933P 2154754..2155047 Escherichia coli O157:H7 str. TW14359 8216704 YP_003078029.1 CDS ECSP_2139 NC_013008.1 2155044 2155235 D hypothetical protein 2155044..2155235 Escherichia coli O157:H7 str. TW14359 8216705 YP_003078030.1 CDS ECSP_2140 NC_013008.1 2155328 2156458 D hypothetical protein 2155328..2156458 Escherichia coli O157:H7 str. TW14359 8216706 YP_003078031.1 CDS ECSP_2141 NC_013008.1 2156464 2156790 D transposase 2156464..2156790 Escherichia coli O157:H7 str. TW14359 8216707 YP_003078032.1 CDS ECSP_2142 NC_013008.1 2156787 2157677 D transposase 2156787..2157677 Escherichia coli O157:H7 str. TW14359 8216708 YP_003078033.1 CDS ECSP_2143 NC_013008.1 2157730 2159112 D exodeoxyribonuclease encoded by cryptic prophage CP-933P 2157730..2159112 Escherichia coli O157:H7 str. TW14359 8216709 YP_003078034.1 CDS xisP NC_013008.1 2159185 2159436 D excisionase of cryptic prophage CP-933P 2159185..2159436 Escherichia coli O157:H7 str. TW14359 8216710 YP_003078035.1 CDS ECSP_2145 NC_013008.1 2159674 2160162 D site-specific recombinase, phage integrase family 2159674..2160162 Escherichia coli O157:H7 str. TW14359 8216711 YP_003078036.1 CDS ynfA NC_013008.1 2160425 2160751 R hypothetical protein complement(2160425..2160751) Escherichia coli O157:H7 str. TW14359 8216712 YP_003078037.1 CDS ynfB NC_013008.1 2160886 2161227 D hypothetical protein 2160886..2161227 Escherichia coli O157:H7 str. TW14359 8216713 YP_003078038.1 CDS speG NC_013008.1 2161262 2161822 D spermidine N1-acetyltransferase 2161262..2161822 Escherichia coli O157:H7 str. TW14359 8216714 YP_003078039.1 CDS ynfC NC_013008.1 2161825 2162535 R hypothetical protein complement(2161825..2162535) Escherichia coli O157:H7 str. TW14359 8216715 YP_003078040.1 CDS ynfD NC_013008.1 2162643 2162948 D hypothetical protein 2162643..2162948 Escherichia coli O157:H7 str. TW14359 8216716 YP_003078041.1 CDS ynfE NC_013008.1 2163147 2165573 D oxidoreductase subunit 2163147..2165573 Escherichia coli O157:H7 str. TW14359 8216717 YP_003078042.1 CDS ynfF NC_013008.1 2165634 2168057 D oxidoreductase subunit 2165634..2168057 Escherichia coli O157:H7 str. TW14359 8216718 YP_003078043.1 CDS ynfG NC_013008.1 2168068 2168685 D oxidoreductase, Fe-S subunit 2168068..2168685 Escherichia coli O157:H7 str. TW14359 8216719 YP_003078044.1 CDS ynfH NC_013008.1 2168687 2169541 D oxidoreductase, membrane subunit 2168687..2169541 Escherichia coli O157:H7 str. TW14359 8216720 YP_003078045.1 CDS dmsD NC_013008.1 2169584 2170198 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 2169584..2170198 Escherichia coli O157:H7 str. TW14359 8216721 YP_003078046.1 CDS clcB NC_013008.1 2170392 2171648 D voltage-gated ClC-type chloride channel ClcB 2170392..2171648 Escherichia coli O157:H7 str. TW14359 8216722 YP_003078047.1 CDS ynfK NC_013008.1 2171601 2172296 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(2171601..2172296) Escherichia coli O157:H7 str. TW14359 8216723 YP_003078048.1 CDS dgsA NC_013008.1 2172421 2173641 R DNA-binding transcriptional repressor complement(2172421..2173641) Escherichia coli O157:H7 str. TW14359 8216724 YP_003078049.1 CDS ynfL NC_013008.1 2173776 2174669 R DNA-binding transcriptional regulator complement(2173776..2174669) Escherichia coli O157:H7 str. TW14359 8216725 YP_003078050.1 CDS ynfM NC_013008.1 2174776 2176029 D transporter 2174776..2176029 Escherichia coli O157:H7 str. TW14359 8216726 YP_003078051.1 CDS asr NC_013008.1 2176453 2176761 D required for growth and survival under moderately acid conditions; acid shock protein 2176453..2176761 Escherichia coli O157:H7 str. TW14359 8216727 YP_003078052.1 CDS ydgD NC_013008.1 2177037 2177858 D peptidase 2177037..2177858 Escherichia coli O157:H7 str. TW14359 8216728 YP_003078053.1 CDS mdtI NC_013008.1 2177897 2178226 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(2177897..2178226) Escherichia coli O157:H7 str. TW14359 8216729 YP_003078054.1 CDS mdtJ NC_013008.1 2178213 2178578 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(2178213..2178578) Escherichia coli O157:H7 str. TW14359 8216730 YP_003078055.1 CDS tqsA NC_013008.1 2178990 2180024 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 2178990..2180024 Escherichia coli O157:H7 str. TW14359 8216731 YP_003078056.1 CDS pntB NC_013008.1 2180049 2181437 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(2180049..2181437) Escherichia coli O157:H7 str. TW14359 8216732 YP_003078057.1 CDS pntA NC_013008.1 2181448 2182980 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(2181448..2182980) Escherichia coli O157:H7 str. TW14359 8216733 YP_003078058.1 CDS ydgH NC_013008.1 2183504 2184448 D hypothetical protein 2183504..2184448 Escherichia coli O157:H7 str. TW14359 8216734 YP_003078059.1 CDS ydgI NC_013008.1 2184634 2186016 D arginine/ornithine antiporter transporter 2184634..2186016 Escherichia coli O157:H7 str. TW14359 8216735 YP_003078060.1 CDS folM NC_013008.1 2186053 2186775 D short chain dehydrogenase 2186053..2186775 Escherichia coli O157:H7 str. TW14359 8216736 YP_003078061.1 CDS ydgC NC_013008.1 2186772 2187107 R hypothetical protein complement(2186772..2187107) Escherichia coli O157:H7 str. TW14359 8216737 YP_003078062.1 CDS rstA NC_013008.1 2187236 2187955 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 2187236..2187955 Escherichia coli O157:H7 str. TW14359 8216738 YP_003078063.1 CDS rstB NC_013008.1 2187959 2189260 D sensor protein RstB 2187959..2189260 Escherichia coli O157:H7 str. TW14359 8216739 YP_003078064.1 CDS tus NC_013008.1 2189336 2190265 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 2189336..2190265 Escherichia coli O157:H7 str. TW14359 8216740 YP_003078065.1 CDS fumC NC_013008.1 2190262 2191665 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(2190262..2191665) Escherichia coli O157:H7 str. TW14359 8216741 YP_003078066.1 CDS fumA NC_013008.1 2191808 2193454 R fumarate hydratase complement(2191808..2193454) Escherichia coli O157:H7 str. TW14359 8216742 YP_003078067.1 CDS manA NC_013008.1 2193653 2194828 D mannose-6-phosphate isomerase 2193653..2194828 Escherichia coli O157:H7 str. TW14359 8216743 YP_003078068.1 CDS ydgA NC_013008.1 2194929 2196437 D hypothetical protein 2194929..2196437 Escherichia coli O157:H7 str. TW14359 8216744 YP_003078069.1 CDS ECSP_2179 NC_013008.1 2196718 2197728 R hypothetical protein complement(2196718..2197728) Escherichia coli O157:H7 str. TW14359 8216745 YP_003078070.1 CDS uidB NC_013008.1 2197785 2199158 R glucuronide transporter complement(2197785..2199158) Escherichia coli O157:H7 str. TW14359 8216746 YP_003078071.1 CDS uidR NC_013008.1 2201359 2201949 R DNA-binding transcriptional repressor complement(2201359..2201949) Escherichia coli O157:H7 str. TW14359 8216748 YP_003078072.1 CDS hdhA NC_013008.1 2202178 2202945 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(2202178..2202945) Escherichia coli O157:H7 str. TW14359 8216749 YP_003078073.1 CDS malI NC_013008.1 2203057 2204085 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(2203057..2204085) Escherichia coli O157:H7 str. TW14359 8216750 YP_003078074.1 CDS malX NC_013008.1 2204260 2205852 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 2204260..2205852 Escherichia coli O157:H7 str. TW14359 8216751 YP_003078075.1 CDS malY NC_013008.1 2205862 2207034 D bifunctional beta-cystathionase, PLP-dependent and regulator of maltose regulon 2205862..2207034 Escherichia coli O157:H7 str. TW14359 8216752 YP_003078076.1 CDS add NC_013008.1 2207138 2208139 D catalyzes the formation of inosine from adenosine; adenosine deaminase 2207138..2208139 Escherichia coli O157:H7 str. TW14359 8216753 YP_003078077.1 CDS ydgJ NC_013008.1 2208175 2209215 R oxidoreductase complement(2208175..2209215) Escherichia coli O157:H7 str. TW14359 8216754 YP_003078078.1 CDS blr NC_013008.1 2209458 2209583 D beta-lactam resistance membrane protein 2209458..2209583 Escherichia coli O157:H7 str. TW14359 8216755 YP_003078079.1 CDS ECSP_2190 NC_013008.1 2209856 2210071 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 2209856..2210071 Escherichia coli O157:H7 str. TW14359 8216756 YP_003078080.1 CDS ydgK NC_013008.1 2210157 2210597 D hypothetical protein 2210157..2210597 Escherichia coli O157:H7 str. TW14359 8216757 YP_003078081.1 CDS rsxA NC_013008.1 2210674 2211255 D Na(+)-translocating NADH-quinone reductase subunit E 2210674..2211255 Escherichia coli O157:H7 str. TW14359 8216758 YP_003078082.1 CDS rsxB NC_013008.1 2211255 2211833 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 2211255..2211833 Escherichia coli O157:H7 str. TW14359 8216759 YP_003078083.1 CDS rsxC NC_013008.1 2211826 2214144 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 2211826..2214144 Escherichia coli O157:H7 str. TW14359 8216760 YP_003078084.1 CDS rnfD NC_013008.1 2214145 2215203 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 2214145..2215203 Escherichia coli O157:H7 str. TW14359 8216761 YP_003078085.1 CDS rsxG NC_013008.1 2215207 2215827 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 2215207..2215827 Escherichia coli O157:H7 str. TW14359 8216762 YP_003078086.1 CDS rsxE NC_013008.1 2215831 2216526 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 2215831..2216526 Escherichia coli O157:H7 str. TW14359 8216763 YP_003078087.1 CDS nth NC_013008.1 2216526 2217161 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 2216526..2217161 Escherichia coli O157:H7 str. TW14359 8216764 YP_003078088.1 CDS tppB NC_013008.1 2217772 2219274 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 2217772..2219274 Escherichia coli O157:H7 str. TW14359 8216765 YP_003078089.1 CDS gst NC_013008.1 2219380 2219985 D glutathionine S-transferase 2219380..2219985 Escherichia coli O157:H7 str. TW14359 8216766 YP_003078090.1 CDS pdxY NC_013008.1 2220029 2220892 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(2220029..2220892) Escherichia coli O157:H7 str. TW14359 8216767 YP_003078091.1 CDS tyrS NC_013008.1 2220951 2222225 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(2220951..2222225) Escherichia coli O157:H7 str. TW14359 8216768 YP_003078092.1 CDS pdxH NC_013008.1 2222354 2223010 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(2222354..2223010) Escherichia coli O157:H7 str. TW14359 8216769 YP_003078093.1 CDS ydhA NC_013008.1 2223069 2223398 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(2223069..2223398) Escherichia coli O157:H7 str. TW14359 8216770 YP_003078094.1 CDS anmK NC_013008.1 2223496 2224605 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(2223496..2224605) Escherichia coli O157:H7 str. TW14359 8216771 YP_003078095.1 CDS slyB NC_013008.1 2224878 2225345 D outer membrane lipoprotein 2224878..2225345 Escherichia coli O157:H7 str. TW14359 8216772 YP_003078096.1 CDS slyA NC_013008.1 2225392 2225826 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(2225392..2225826) Escherichia coli O157:H7 str. TW14359 8216773 YP_003078097.1 CDS ydhI NC_013008.1 2226027 2226263 D inner membrane protein 2226027..2226263 Escherichia coli O157:H7 str. TW14359 8216774 YP_003078098.1 CDS ydhJ NC_013008.1 2226266 2227123 D UDP pyrophosphate phosphatase 2226266..2227123 Escherichia coli O157:H7 str. TW14359 8216775 YP_003078099.1 CDS ydhK NC_013008.1 2227123 2229135 D hypothetical protein 2227123..2229135 Escherichia coli O157:H7 str. TW14359 8216776 YP_003078100.1 CDS sodC NC_013008.1 2229136 2229657 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(2229136..2229657) Escherichia coli O157:H7 str. TW14359 8216777 YP_003078101.1 CDS ydhF NC_013008.1 2229846 2230634 R oxidoreductase complement(2229846..2230634) Escherichia coli O157:H7 str. TW14359 8216778 YP_003078102.1 CDS ydhL NC_013008.1 2230683 2230922 R hypothetical protein complement(2230683..2230922) Escherichia coli O157:H7 str. TW14359 8216779 YP_003078103.1 CDS ydhM NC_013008.1 2231025 2231624 D DNA-binding transcriptional regulator 2231025..2231624 Escherichia coli O157:H7 str. TW14359 8216780 YP_003078104.1 CDS nemA NC_013008.1 2231661 2232758 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 2231661..2232758 Escherichia coli O157:H7 str. TW14359 8216781 YP_003078105.1 CDS gloA NC_013008.1 2232839 2233246 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 2232839..2233246 Escherichia coli O157:H7 str. TW14359 8216782 YP_003078106.1 CDS rnt NC_013008.1 2233349 2233996 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2233349..2233996 Escherichia coli O157:H7 str. TW14359 8216783 YP_003078107.1 CDS lhr NC_013008.1 2234089 2238705 D similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; ATP-dependent helicase Lhr 2234089..2238705 Escherichia coli O157:H7 str. TW14359 8216784 YP_003078108.1 CDS grxD NC_013008.1 2238756 2239103 R hypothetical protein complement(2238756..2239103) Escherichia coli O157:H7 str. TW14359 8216785 YP_003078109.1 CDS ECSP_2220 NC_013008.1 2239228 2239338 R hypothetical protein complement(2239228..2239338) Escherichia coli O157:H7 str. TW14359 8216786 YP_003078110.1 CDS ydhO NC_013008.1 2239438 2240253 D lipoprotein 2239438..2240253 Escherichia coli O157:H7 str. TW14359 8216787 YP_003078111.1 CDS sodB NC_013008.1 2240381 2240962 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 2240381..2240962 Escherichia coli O157:H7 str. TW14359 8216788 YP_003078112.1 CDS ydhP NC_013008.1 2241108 2242277 R transporter complement(2241108..2242277) Escherichia coli O157:H7 str. TW14359 8216789 YP_003078113.1 CDS ECSP_2224 NC_013008.1 2242443 2242562 R membrane protein complement(2242443..2242562) Escherichia coli O157:H7 str. TW14359 8216790 YP_003078114.1 CDS purR NC_013008.1 2242831 2243856 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 2242831..2243856 Escherichia coli O157:H7 str. TW14359 8216791 YP_003078115.1 CDS ydhB NC_013008.1 2243853 2244785 R DNA-binding transcriptional regulator complement(2243853..2244785) Escherichia coli O157:H7 str. TW14359 8216792 YP_003078116.1 CDS ydhC NC_013008.1 2244898 2246109 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2244898..2246109 Escherichia coli O157:H7 str. TW14359 8216793 YP_003078117.1 CDS cfa NC_013008.1 2246400 2247548 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 2246400..2247548 Escherichia coli O157:H7 str. TW14359 8216794 YP_003078118.1 CDS ribC NC_013008.1 2247588 2248229 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(2247588..2248229) Escherichia coli O157:H7 str. TW14359 8216795 YP_003078119.1 CDS mdtK NC_013008.1 2248444 2249817 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 2248444..2249817 Escherichia coli O157:H7 str. TW14359 8216796 YP_003078120.1 CDS ydhQ NC_013008.1 2249858 2251114 R hypothetical protein complement(2249858..2251114) Escherichia coli O157:H7 str. TW14359 8216797 YP_003078121.1 CDS ydhR NC_013008.1 2251687 2251992 D hypothetical protein 2251687..2251992 Escherichia coli O157:H7 str. TW14359 8216800 YP_003078122.1 CDS ydhS NC_013008.1 2252118 2253722 D hypothetical protein 2252118..2253722 Escherichia coli O157:H7 str. TW14359 8216801 YP_003078123.1 CDS ydhT NC_013008.1 2253734 2254546 R hypothetical protein complement(2253734..2254546) Escherichia coli O157:H7 str. TW14359 8216802 YP_003078124.1 CDS ydhU NC_013008.1 2254550 2255335 R cytochrome complement(2254550..2255335) Escherichia coli O157:H7 str. TW14359 8216803 YP_003078125.1 CDS ydhX NC_013008.1 2255332 2256000 R 4Fe-4S ferredoxin complement(2255332..2256000) Escherichia coli O157:H7 str. TW14359 8216804 YP_003078126.1 CDS ydhW NC_013008.1 2256064 2256711 R hypothetical protein complement(2256064..2256711) Escherichia coli O157:H7 str. TW14359 8216805 YP_003078127.1 CDS ydhV NC_013008.1 2256715 2258817 R oxidoreductase complement(2256715..2258817) Escherichia coli O157:H7 str. TW14359 8216806 YP_003078128.1 CDS ydhY NC_013008.1 2258838 2259464 R hypothetical protein complement(2258838..2259464) Escherichia coli O157:H7 str. TW14359 8216807 YP_003078129.1 CDS ydhZ NC_013008.1 2259920 2260129 R hypothetical protein complement(2259920..2260129) Escherichia coli O157:H7 str. TW14359 8216808 YP_003078130.1 CDS pykF NC_013008.1 2260686 2262098 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2260686..2262098 Escherichia coli O157:H7 str. TW14359 8216809 YP_003078131.1 CDS lpp NC_013008.1 2262409 2262645 D murein lipoprotein 2262409..2262645 Escherichia coli O157:H7 str. TW14359 8216810 YP_003078132.1 CDS ynhG NC_013008.1 2262708 2263712 R hypothetical protein complement(2262708..2263712) Escherichia coli O157:H7 str. TW14359 8216811 YP_003078133.1 CDS sufE NC_013008.1 2263861 2264277 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(2263861..2264277) Escherichia coli O157:H7 str. TW14359 8216812 YP_003078134.1 CDS sufS NC_013008.1 2264290 2265510 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(2264290..2265510) Escherichia coli O157:H7 str. TW14359 8216813 YP_003078135.1 CDS sufD NC_013008.1 2265507 2266778 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(2265507..2266778) Escherichia coli O157:H7 str. TW14359 8216814 YP_003078136.1 CDS sufC NC_013008.1 2266753 2267499 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase complement(2266753..2267499) Escherichia coli O157:H7 str. TW14359 8216815 YP_003078137.1 CDS sufB NC_013008.1 2267509 2268996 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(2267509..2268996) Escherichia coli O157:H7 str. TW14359 8216816 YP_003078138.1 CDS sufA NC_013008.1 2269005 2269373 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(2269005..2269373) Escherichia coli O157:H7 str. TW14359 8216817 YP_003078139.1 CDS ydiH NC_013008.1 2269922 2270110 R hypothetical protein complement(2269922..2270110) Escherichia coli O157:H7 str. TW14359 8216818 YP_003078140.1 CDS ydiI NC_013008.1 2270210 2270620 R hypothetical protein complement(2270210..2270620) Escherichia coli O157:H7 str. TW14359 8216819 YP_003078141.1 CDS ydiJ NC_013008.1 2270617 2273673 R FAD-linked oxidoreductase complement(2270617..2273673) Escherichia coli O157:H7 str. TW14359 8216820 YP_003078142.1 CDS ydiK NC_013008.1 2274062 2275174 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 2274062..2275174 Escherichia coli O157:H7 str. TW14359 8216821 YP_003078143.1 CDS ydiL NC_013008.1 2275603 2275959 D hypothetical protein 2275603..2275959 Escherichia coli O157:H7 str. TW14359 8216822 YP_003078144.1 CDS ydiM NC_013008.1 2276059 2277273 D transporter 2276059..2277273 Escherichia coli O157:H7 str. TW14359 8216823 YP_003078145.1 CDS ydiN NC_013008.1 2277500 2278765 D transporter 2277500..2278765 Escherichia coli O157:H7 str. TW14359 8216824 YP_003078146.1 CDS ydiB NC_013008.1 2278777 2279643 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2278777..2279643 Escherichia coli O157:H7 str. TW14359 8216825 YP_003078147.1 CDS aroD NC_013008.1 2279674 2280432 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2279674..2280432 Escherichia coli O157:H7 str. TW14359 8216826 YP_003078148.1 CDS ydiF NC_013008.1 2280577 2282172 D acyl-CoA transferase 2280577..2282172 Escherichia coli O157:H7 str. TW14359 8216827 YP_003078149.1 CDS ydiO NC_013008.1 2282186 2283337 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 2282186..2283337 Escherichia coli O157:H7 str. TW14359 8216828 YP_003078150.1 CDS ydiP NC_013008.1 2283380 2284291 R DNA-binding transcriptional regulator complement(2283380..2284291) Escherichia coli O157:H7 str. TW14359 8216829 YP_003078151.1 CDS ydiQ NC_013008.1 2284607 2285371 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 2284607..2285371 Escherichia coli O157:H7 str. TW14359 8216830 YP_003078152.1 CDS ydiR NC_013008.1 2285391 2286329 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2285391..2286329 Escherichia coli O157:H7 str. TW14359 8216831 YP_003078153.1 CDS ydiS NC_013008.1 2286385 2287674 D hypothetical protein 2286385..2287674 Escherichia coli O157:H7 str. TW14359 8216832 YP_003078154.1 CDS ydiT NC_013008.1 2287671 2287964 D 4Fe-4S ferredoxin-type protein 2287671..2287964 Escherichia coli O157:H7 str. TW14359 8216833 YP_003078155.1 CDS fadK NC_013008.1 2288021 2289562 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 2288021..2289562 Escherichia coli O157:H7 str. TW14359 8216834 YP_003078156.1 CDS pps NC_013008.1 2289723 2292101 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(2289723..2292101) Escherichia coli O157:H7 str. TW14359 8216835 YP_003078157.1 CDS ydiA NC_013008.1 2292434 2293267 D hypothetical protein 2292434..2293267 Escherichia coli O157:H7 str. TW14359 8216836 YP_003078158.1 CDS aroH NC_013008.1 2293424 2294470 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2293424..2294470 Escherichia coli O157:H7 str. TW14359 8216837 YP_003078159.1 CDS ydiE NC_013008.1 2294602 2294793 D hypothetical protein 2294602..2294793 Escherichia coli O157:H7 str. TW14359 8216838 YP_003078160.1 CDS ydiU NC_013008.1 2294797 2296233 R hypothetical protein complement(2294797..2296233) Escherichia coli O157:H7 str. TW14359 8216839 YP_003078161.1 CDS ydiV NC_013008.1 2296296 2297009 R hypothetical protein complement(2296296..2297009) Escherichia coli O157:H7 str. TW14359 8216840 YP_003078162.1 CDS nlpC NC_013008.1 2297256 2297720 R lipoprotein complement(2297256..2297720) Escherichia coli O157:H7 str. TW14359 8216841 YP_003078163.1 CDS btuD NC_013008.1 2297798 2298547 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(2297798..2298547) Escherichia coli O157:H7 str. TW14359 8216842 YP_003078164.1 CDS btuE NC_013008.1 2298547 2299098 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(2298547..2299098) Escherichia coli O157:H7 str. TW14359 8216843 YP_003078165.1 CDS btuC NC_013008.1 2299161 2300141 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(2299161..2300141) Escherichia coli O157:H7 str. TW14359 8216844 YP_003078166.1 CDS ihfA NC_013008.1 2300242 2300541 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(2300242..2300541) Escherichia coli O157:H7 str. TW14359 8216845 YP_003078167.1 CDS pheT NC_013008.1 2300546 2302933 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2300546..2302933) Escherichia coli O157:H7 str. TW14359 8216846 YP_003078168.1 CDS pheS NC_013008.1 2302948 2303931 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2302948..2303931) Escherichia coli O157:H7 str. TW14359 8216847 YP_003078170.1 CDS rplT NC_013008.1 2304381 2304737 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2304381..2304737) Escherichia coli O157:H7 str. TW14359 8216849 YP_003078171.1 CDS rpmI NC_013008.1 2304790 2304987 R 50S ribosomal protein L35 complement(2304790..2304987) Escherichia coli O157:H7 str. TW14359 8216850 YP_003078172.1 CDS infC NC_013008.1 2305084 2305626 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(2305084..2305626) Escherichia coli O157:H7 str. TW14359 8216851 YP_003078173.1 CDS thrS NC_013008.1 2305630 2307558 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(2305630..2307558) Escherichia coli O157:H7 str. TW14359 8216852 YP_003078174.1 CDS espL1 NC_013008.1 2308081 2309979 D non-LEE-encoded type III effector 2308081..2309979 Escherichia coli O157:H7 str. TW14359 8216853 YP_003078175.1 CDS yniD NC_013008.1 2310154 2310261 D hypothetical protein 2310154..2310261 Escherichia coli O157:H7 str. TW14359 8216854 YP_003078176.1 CDS ydiY NC_013008.1 2310314 2311072 R hypothetical protein complement(2310314..2311072) Escherichia coli O157:H7 str. TW14359 8216855 YP_003078177.1 CDS ECSP_2290 NC_013008.1 2311213 2311320 D hypothetical protein 2311213..2311320 Escherichia coli O157:H7 str. TW14359 8216856 YP_003078178.1 CDS pfkB NC_013008.1 2311359 2312288 D 6-phosphofructokinase 2311359..2312288 Escherichia coli O157:H7 str. TW14359 8216857 YP_003078179.1 CDS ydiZ NC_013008.1 2312389 2312679 D hypothetical protein 2312389..2312679 Escherichia coli O157:H7 str. TW14359 8216858 YP_003078180.1 CDS yniA NC_013008.1 2312785 2313645 D phosphotransferase/kinase 2312785..2313645 Escherichia coli O157:H7 str. TW14359 8216859 YP_003078181.1 CDS yniB NC_013008.1 2313686 2314222 R inner membrane protein complement(2313686..2314222) Escherichia coli O157:H7 str. TW14359 8216860 YP_003078182.1 CDS yniC NC_013008.1 2314369 2315037 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2314369..2315037 Escherichia coli O157:H7 str. TW14359 8216861 YP_003078183.1 CDS ydjM NC_013008.1 2315200 2315790 D hypothetical protein 2315200..2315790 Escherichia coli O157:H7 str. TW14359 8216862 YP_003078184.1 CDS ydjN NC_013008.1 2315923 2317314 D transporter 2315923..2317314 Escherichia coli O157:H7 str. TW14359 8216863 YP_003078185.1 CDS ydjO NC_013008.1 2317365 2318132 R hypothetical protein complement(2317365..2318132) Escherichia coli O157:H7 str. TW14359 8216864 YP_003078186.1 CDS cedA NC_013008.1 2318409 2318651 R cell division modulator complement(2318409..2318651) Escherichia coli O157:H7 str. TW14359 8216865 YP_003078187.1 CDS katE NC_013008.1 2318855 2321116 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2318855..2321116 Escherichia coli O157:H7 str. TW14359 8216866 YP_003078188.1 CDS chbG NC_013008.1 2321163 2321921 R hypothetical protein complement(2321163..2321921) Escherichia coli O157:H7 str. TW14359 8216867 YP_003078189.1 CDS chbF NC_013008.1 2321934 2323286 R cryptic phospho-beta-glucosidase, NAD(P)-binding complement(2321934..2323286) Escherichia coli O157:H7 str. TW14359 8216868 YP_003078190.1 CDS chbR NC_013008.1 2323391 2324233 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(2323391..2324233) Escherichia coli O157:H7 str. TW14359 8216869 YP_003078191.1 CDS chbA NC_013008.1 2324241 2324591 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(2324241..2324591) Escherichia coli O157:H7 str. TW14359 8216870 YP_003078192.1 CDS chbC NC_013008.1 2324642 2326000 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(2324642..2326000) Escherichia coli O157:H7 str. TW14359 8216871 YP_003078193.1 CDS chbB NC_013008.1 2326085 2326405 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(2326085..2326405) Escherichia coli O157:H7 str. TW14359 8216872 YP_003078194.1 CDS osmE NC_013008.1 2326705 2327043 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(2326705..2327043) Escherichia coli O157:H7 str. TW14359 8216873 YP_003078195.1 CDS nadE NC_013008.1 2327245 2328072 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2327245..2328072 Escherichia coli O157:H7 str. TW14359 8216874 YP_003078196.1 CDS cho NC_013008.1 2328302 2329189 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2328302..2329189 Escherichia coli O157:H7 str. TW14359 8216875 YP_003078197.1 CDS ECSP_2310 NC_013008.1 2329149 2329724 R hypothetical protein complement(2329149..2329724) Escherichia coli O157:H7 str. TW14359 8216876 YP_003078198.1 CDS spy NC_013008.1 2329927 2330412 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein complement(2329927..2330412) Escherichia coli O157:H7 str. TW14359 8216877 YP_003078199.1 CDS astE NC_013008.1 2330742 2331710 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(2330742..2331710) Escherichia coli O157:H7 str. TW14359 8216878 YP_003078200.1 CDS astB NC_013008.1 2331703 2333046 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(2331703..2333046) Escherichia coli O157:H7 str. TW14359 8216879 YP_003078201.1 CDS astD NC_013008.1 2333043 2334521 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(2333043..2334521) Escherichia coli O157:H7 str. TW14359 8216880 YP_003078202.1 CDS astA NC_013008.1 2334518 2335552 R arginine succinyltransferase complement(2334518..2335552) Escherichia coli O157:H7 str. TW14359 8216881 YP_003078203.1 CDS astC NC_013008.1 2335549 2336769 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(2335549..2336769) Escherichia coli O157:H7 str. TW14359 8216882 YP_003078204.1 CDS xthA NC_013008.1 2337215 2338021 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2337215..2338021 Escherichia coli O157:H7 str. TW14359 8216883 YP_003078205.1 CDS ydjX NC_013008.1 2338188 2338898 D inner membrane protein 2338188..2338898 Escherichia coli O157:H7 str. TW14359 8216884 YP_003078206.1 CDS ydjY NC_013008.1 2338903 2339580 D hypothetical protein 2338903..2339580 Escherichia coli O157:H7 str. TW14359 8216885 YP_003078207.1 CDS ydjZ NC_013008.1 2339595 2340302 D hypothetical protein 2339595..2340302 Escherichia coli O157:H7 str. TW14359 8216886 YP_003078208.1 CDS ynjA NC_013008.1 2340302 2340850 D hypothetical protein 2340302..2340850 Escherichia coli O157:H7 str. TW14359 8216887 YP_003078209.1 CDS ynjB NC_013008.1 2340860 2342026 D ABC transporter solute-binding protein 2340860..2342026 Escherichia coli O157:H7 str. TW14359 8216888 YP_003078210.1 CDS ynjC NC_013008.1 2341999 2343534 D fused transporter subunits of ABC superfamily: membrane components 2341999..2343534 Escherichia coli O157:H7 str. TW14359 8216889 YP_003078211.1 CDS ynjD NC_013008.1 2343534 2344187 D ABC transporter ATP-binding protein 2343534..2344187 Escherichia coli O157:H7 str. TW14359 8216890 YP_003078212.1 CDS ynjE NC_013008.1 2344254 2345561 D thiosulfate sulfur transferase 2344254..2345561 Escherichia coli O157:H7 str. TW14359 8216891 YP_003078213.1 CDS ynjF NC_013008.1 2345570 2346190 R phosphatidyl transferase, inner membrane protein complement(2345570..2346190) Escherichia coli O157:H7 str. TW14359 8216892 YP_003078214.1 CDS nudG NC_013008.1 2346277 2346684 D pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2346277..2346684 Escherichia coli O157:H7 str. TW14359 8216893 YP_003078215.1 CDS ynjH NC_013008.1 2346650 2346922 R hypothetical protein complement(2346650..2346922) Escherichia coli O157:H7 str. TW14359 8216894 YP_003078216.1 CDS gdhA NC_013008.1 2347158 2348501 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2347158..2348501 Escherichia coli O157:H7 str. TW14359 8216895 YP_003078217.1 CDS ynjI NC_013008.1 2348618 2349658 R hypothetical protein complement(2348618..2349658) Escherichia coli O157:H7 str. TW14359 8216896 YP_003078218.1 CDS topB NC_013008.1 2349786 2351747 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(2349786..2351747) Escherichia coli O157:H7 str. TW14359 8216897 YP_003078219.1 CDS selD NC_013008.1 2351752 2352795 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(2351752..2352795) Escherichia coli O157:H7 str. TW14359 8216898 YP_003078220.1 CDS ydjA NC_013008.1 2352912 2353463 R hypothetical protein complement(2352912..2353463) Escherichia coli O157:H7 str. TW14359 8216899 YP_003078221.1 CDS sppA NC_013008.1 2353624 2355480 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2353624..2355480 Escherichia coli O157:H7 str. TW14359 8216900 YP_003078222.1 CDS ECSP_2335 NC_013008.1 2355596 2356306 D hypothetical protein 2355596..2356306 Escherichia coli O157:H7 str. TW14359 8216901 YP_003078223.1 CDS ansA NC_013008.1 2356438 2357454 D converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2356438..2357454 Escherichia coli O157:H7 str. TW14359 8216902 YP_003078224.1 CDS pncA NC_013008.1 2357465 2358106 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2357465..2358106 Escherichia coli O157:H7 str. TW14359 8216903 YP_003078225.1 CDS ydjE NC_013008.1 2358199 2359449 R transporter complement(2358199..2359449) Escherichia coli O157:H7 str. TW14359 8216904 YP_003078226.1 CDS ECSP_2339 NC_013008.1 2359512 2359838 D transposase, IS629 2359512..2359838 Escherichia coli O157:H7 str. TW14359 8216905 YP_003078227.1 CDS ECSP_2340 NC_013008.1 2359838 2360725 D transposase, IS629 2359838..2360725 Escherichia coli O157:H7 str. TW14359 8216906 YP_003078228.1 CDS ECSP_2341 NC_013008.1 2360843 2360986 D hypothetical protein 2360843..2360986 Escherichia coli O157:H7 str. TW14359 8216907 YP_003078229.1 CDS ydjF NC_013008.1 2360988 2361746 R DNA-binding transcriptional regulator complement(2360988..2361746) Escherichia coli O157:H7 str. TW14359 8216908 YP_003078230.1 CDS ydjG NC_013008.1 2361883 2362863 R oxidoreductase complement(2361883..2362863) Escherichia coli O157:H7 str. TW14359 8216909 YP_003078231.1 CDS ydjH NC_013008.1 2362873 2363805 R kinase complement(2362873..2363805) Escherichia coli O157:H7 str. TW14359 8216910 YP_003078232.1 CDS ydjI NC_013008.1 2363810 2364646 R aldolase complement(2363810..2364646) Escherichia coli O157:H7 str. TW14359 8216911 YP_003078233.1 CDS ydjJ NC_013008.1 2364667 2365710 R oxidoreductase complement(2364667..2365710) Escherichia coli O157:H7 str. TW14359 8216912 YP_003078234.1 CDS ydjK NC_013008.1 2365727 2367106 R transporter complement(2365727..2367106) Escherichia coli O157:H7 str. TW14359 8216913 YP_003078235.1 CDS ydjL NC_013008.1 2367133 2368209 R oxidoreductase complement(2367133..2368209) Escherichia coli O157:H7 str. TW14359 8216914 YP_003078236.1 CDS yeaC NC_013008.1 2368579 2368851 R hypothetical protein complement(2368579..2368851) Escherichia coli O157:H7 str. TW14359 8216915 YP_003078237.1 CDS yeaA NC_013008.1 2368893 2369306 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(2368893..2369306) Escherichia coli O157:H7 str. TW14359 8216916 YP_003078238.1 CDS gapA NC_013008.1 2369648 2370643 D glyceraldehyde-3-phosphate dehydrogenase A 2369648..2370643 Escherichia coli O157:H7 str. TW14359 8216917 YP_003078239.1 CDS yeaD NC_013008.1 2370727 2371611 D hypothetical protein 2370727..2371611 Escherichia coli O157:H7 str. TW14359 8216918 YP_003078240.1 CDS yeaE NC_013008.1 2371662 2372516 R oxidoreductase complement(2371662..2372516) Escherichia coli O157:H7 str. TW14359 8216919 YP_003078241.1 CDS mipA NC_013008.1 2372606 2373352 R scaffolding protein for murein synthesizing machinery complement(2372606..2373352) Escherichia coli O157:H7 str. TW14359 8216920 YP_003078242.1 CDS yeaG NC_013008.1 2373788 2375722 D hypothetical protein 2373788..2375722 Escherichia coli O157:H7 str. TW14359 8216921 YP_003078243.1 CDS yeaH NC_013008.1 2375835 2377118 D hypothetical protein 2375835..2377118 Escherichia coli O157:H7 str. TW14359 8216922 YP_003078244.1 CDS yeaI NC_013008.1 2377406 2378740 D diguanylate cyclase 2377406..2378740 Escherichia coli O157:H7 str. TW14359 8216923 YP_003078245.1 CDS yeaJ NC_013008.1 2378921 2380411 D diguanylate cyclase 2378921..2380411 Escherichia coli O157:H7 str. TW14359 8216924 YP_003078246.1 CDS yeaK NC_013008.1 2380454 2380957 D hypothetical protein 2380454..2380957 Escherichia coli O157:H7 str. TW14359 8216925 YP_003078247.1 CDS yoaI NC_013008.1 2380958 2381062 R hypothetical protein complement(2380958..2381062) Escherichia coli O157:H7 str. TW14359 8216926 YP_003078248.1 CDS yeaL NC_013008.1 2381232 2381678 D hypothetical protein 2381232..2381678 Escherichia coli O157:H7 str. TW14359 8216927 YP_003078249.1 CDS yeaM NC_013008.1 2381635 2382456 R DNA-binding transcriptional regulator complement(2381635..2382456) Escherichia coli O157:H7 str. TW14359 8216928 YP_003078250.1 CDS yeaN NC_013008.1 2382553 2383734 D transporter 2382553..2383734 Escherichia coli O157:H7 str. TW14359 8216929 YP_003078251.1 CDS yeaO NC_013008.1 2383789 2384136 D hypothetical protein 2383789..2384136 Escherichia coli O157:H7 str. TW14359 8216930 YP_003078252.1 CDS yoaF NC_013008.1 2384158 2384412 R outer membrane protein complement(2384158..2384412) Escherichia coli O157:H7 str. TW14359 8216931 YP_003078253.1 CDS yeaP NC_013008.1 2384595 2385620 D diguanylate cyclase 2384595..2385620 Escherichia coli O157:H7 str. TW14359 8216932 YP_003078254.1 CDS yeaQ NC_013008.1 2385887 2386135 R hypothetical protein complement(2385887..2386135) Escherichia coli O157:H7 str. TW14359 8216933 YP_003078255.1 CDS yoaG NC_013008.1 2386282 2386464 R hypothetical protein complement(2386282..2386464) Escherichia coli O157:H7 str. TW14359 8216934 YP_003078256.1 CDS yeaR NC_013008.1 2386468 2386827 R hypothetical protein complement(2386468..2386827) Escherichia coli O157:H7 str. TW14359 8216935 YP_003078257.1 CDS yeaS NC_013008.1 2387000 2387638 R leucine export protein LeuE complement(2387000..2387638) Escherichia coli O157:H7 str. TW14359 8216936 YP_003078258.1 CDS yeaT NC_013008.1 2387765 2388688 R DNA-binding transcriptional regulator complement(2387765..2388688) Escherichia coli O157:H7 str. TW14359 8216937 YP_003078259.1 CDS yeaU NC_013008.1 2388791 2389876 D dehydrogenase 2388791..2389876 Escherichia coli O157:H7 str. TW14359 8216938 YP_003078260.1 CDS yeaV NC_013008.1 2390127 2391737 D member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2390127..2391737 Escherichia coli O157:H7 str. TW14359 8216939 YP_003078261.1 CDS yeaW NC_013008.1 2391769 2392893 D 2Fe-2S cluster-containing protein 2391769..2392893 Escherichia coli O157:H7 str. TW14359 8216940 YP_003078262.1 CDS yeaX NC_013008.1 2392949 2393914 D oxidoreductase 2392949..2393914 Escherichia coli O157:H7 str. TW14359 8216941 YP_003078263.1 CDS rnd NC_013008.1 2393968 2395095 R ribonuclease D complement(2393968..2395095) Escherichia coli O157:H7 str. TW14359 8216942 YP_003078264.1 CDS fadD NC_013008.1 2395165 2396850 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2395165..2396850) Escherichia coli O157:H7 str. TW14359 8216943 YP_003078265.1 CDS yeaY NC_013008.1 2397055 2397636 R lipoprotein complement(2397055..2397636) Escherichia coli O157:H7 str. TW14359 8216944 YP_003078266.1 CDS yeaZ NC_013008.1 2397676 2398371 R peptidase complement(2397676..2398371) Escherichia coli O157:H7 str. TW14359 8216945 YP_003078267.1 CDS yoaA NC_013008.1 2398429 2400339 R hypothetical protein complement(2398429..2400339) Escherichia coli O157:H7 str. TW14359 8216946 YP_003078268.1 CDS yoaB NC_013008.1 2400471 2400815 D hypothetical protein 2400471..2400815 Escherichia coli O157:H7 str. TW14359 8216947 YP_003078269.1 CDS ECSP_2382 NC_013008.1 2400849 2400980 R hypothetical protein complement(2400849..2400980) Escherichia coli O157:H7 str. TW14359 8216948 YP_003078270.1 CDS yoaC NC_013008.1 2401237 2401536 D hypothetical protein 2401237..2401536 Escherichia coli O157:H7 str. TW14359 8216949 YP_003078271.1 CDS yoaH NC_013008.1 2401656 2401835 R hypothetical protein complement(2401656..2401835) Escherichia coli O157:H7 str. TW14359 8216950 YP_003078272.1 CDS pabB NC_013008.1 2401909 2403270 D aminodeoxychorismate synthase subunit I 2401909..2403270 Escherichia coli O157:H7 str. TW14359 8216951 YP_003078273.1 CDS yeaB NC_013008.1 2403274 2403852 D hypothetical protein 2403274..2403852 Escherichia coli O157:H7 str. TW14359 8216952 YP_003078274.1 CDS sdaA NC_013008.1 2404036 2405400 D L-serine deaminase I 2404036..2405400 Escherichia coli O157:H7 str. TW14359 8216953 YP_003078275.1 CDS yoaD NC_013008.1 2405531 2407129 D phosphodiesterase 2405531..2407129 Escherichia coli O157:H7 str. TW14359 8216954 YP_003078276.1 CDS yoaE NC_013008.1 2407133 2408689 R fused membrane protein, conserved protein complement(2407133..2408689) Escherichia coli O157:H7 str. TW14359 8216955 YP_003078277.1 CDS manX NC_013008.1 2409152 2410123 D mannose-specific PTS enzyme 2409152..2410123 Escherichia coli O157:H7 str. TW14359 8216956 YP_003078278.1 CDS manY NC_013008.1 2410186 2410986 D PTS system mannose-specific protein subunit IIC 2410186..2410986 Escherichia coli O157:H7 str. TW14359 8216957 YP_003078279.1 CDS manZ NC_013008.1 2410990 2411850 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2410990..2411850 Escherichia coli O157:H7 str. TW14359 8216958 YP_003078280.1 CDS yobD NC_013008.1 2411905 2412363 D hypothetical protein 2411905..2412363 Escherichia coli O157:H7 str. TW14359 8216959 YP_003078281.1 CDS yebN NC_013008.1 2412793 2413359 D membrane protein YebN; hypothetical protein 2412793..2413359 Escherichia coli O157:H7 str. TW14359 8216960 YP_003078282.1 CDS rrmA NC_013008.1 2413356 2414165 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase complement(2413356..2414165) Escherichia coli O157:H7 str. TW14359 8216961 YP_003078283.1 CDS cspC NC_013008.1 2414331 2414540 R cold shock-like protein CspC complement(2414331..2414540) Escherichia coli O157:H7 str. TW14359 8216962 YP_003078284.1 CDS yobF NC_013008.1 2414553 2414696 R hypothetical protein complement(2414553..2414696) Escherichia coli O157:H7 str. TW14359 8216963 YP_003078285.1 CDS yebO NC_013008.1 2415365 2415652 R hypothetical protein complement(2415365..2415652) Escherichia coli O157:H7 str. TW14359 8216964 YP_003078286.1 CDS yobG NC_013008.1 2415727 2415870 R hypothetical protein complement(2415727..2415870) Escherichia coli O157:H7 str. TW14359 8216965 YP_003078287.1 CDS yobH NC_013008.1 2416030 2416269 D hypothetical protein 2416030..2416269 Escherichia coli O157:H7 str. TW14359 8216966 YP_003078288.1 CDS kdgR NC_013008.1 2416413 2417204 R DNA-binding transcriptional regulatory protein KdgR complement(2416413..2417204) Escherichia coli O157:H7 str. TW14359 8216967 YP_003078289.1 CDS yebQ NC_013008.1 2417381 2418754 D transporter 2417381..2418754 Escherichia coli O157:H7 str. TW14359 8216968 YP_003078290.1 CDS htpX NC_013008.1 2418800 2419681 R metalloprotease; heat shock protein HtpX complement(2418800..2419681) Escherichia coli O157:H7 str. TW14359 8216969 YP_003078291.1 CDS prc NC_013008.1 2419873 2421921 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2419873..2421921) Escherichia coli O157:H7 str. TW14359 8216970 YP_003078292.1 CDS proQ NC_013008.1 2421941 2422639 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(2421941..2422639) Escherichia coli O157:H7 str. TW14359 8216971 YP_003078293.1 CDS yebR NC_013008.1 2422736 2423233 R hypothetical protein complement(2422736..2423233) Escherichia coli O157:H7 str. TW14359 8216972 YP_003078294.1 CDS yebS NC_013008.1 2423363 2424646 D hypothetical protein 2423363..2424646 Escherichia coli O157:H7 str. TW14359 8216973 YP_003078295.1 CDS yebT NC_013008.1 2424615 2427248 D hypothetical protein 2424615..2427248 Escherichia coli O157:H7 str. TW14359 8216974 YP_003078296.1 CDS yebU NC_013008.1 2427329 2428768 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2427329..2428768 Escherichia coli O157:H7 str. TW14359 8216975 YP_003078297.1 CDS yebV NC_013008.1 2428886 2429122 D hypothetical protein 2428886..2429122 Escherichia coli O157:H7 str. TW14359 8216976 YP_003078298.1 CDS yebW NC_013008.1 2429227 2429418 D hypothetical protein 2429227..2429418 Escherichia coli O157:H7 str. TW14359 8216977 YP_003078299.1 CDS pphA NC_013008.1 2429419 2430075 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2429419..2430075) Escherichia coli O157:H7 str. TW14359 8216978 YP_003078300.1 CDS yebY NC_013008.1 2430471 2430812 R hypothetical protein complement(2430471..2430812) Escherichia coli O157:H7 str. TW14359 8216979 YP_003078301.1 CDS yebZ NC_013008.1 2430825 2431697 R inner membrane protein complement(2430825..2431697) Escherichia coli O157:H7 str. TW14359 8216980 YP_003078302.1 CDS yobA NC_013008.1 2431701 2432075 R hypothetical protein complement(2431701..2432075) Escherichia coli O157:H7 str. TW14359 8216981 YP_003078303.1 CDS holE NC_013008.1 2432214 2432444 D DNA polymerase III subunit theta 2432214..2432444 Escherichia coli O157:H7 str. TW14359 8216982 YP_003078304.1 CDS yobB NC_013008.1 2432546 2433202 D hypothetical protein 2432546..2433202 Escherichia coli O157:H7 str. TW14359 8216983 YP_003078305.1 CDS exoX NC_013008.1 2433226 2433888 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2433226..2433888 Escherichia coli O157:H7 str. TW14359 8216984 YP_003078306.1 CDS ptrB NC_013008.1 2433885 2435945 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(2433885..2435945) Escherichia coli O157:H7 str. TW14359 8216985 YP_003078307.1 CDS yebE NC_013008.1 2436154 2436813 R hypothetical protein complement(2436154..2436813) Escherichia coli O157:H7 str. TW14359 8216986 YP_003078308.1 CDS yebF NC_013008.1 2437140 2437496 R hypothetical protein; unknown function; hypothetical protein complement(2437140..2437496) Escherichia coli O157:H7 str. TW14359 8216987 YP_003078309.1 CDS yebG NC_013008.1 2437563 2437853 R DNA damage-inducible protein YebG complement(2437563..2437853) Escherichia coli O157:H7 str. TW14359 8216988 YP_003078310.1 CDS purT NC_013008.1 2437987 2439165 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2437987..2439165 Escherichia coli O157:H7 str. TW14359 8216989 YP_003078311.1 CDS eda NC_013008.1 2439221 2439862 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2439221..2439862) Escherichia coli O157:H7 str. TW14359 8216990 YP_003078312.1 CDS edd NC_013008.1 2439899 2441710 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2439899..2441710) Escherichia coli O157:H7 str. TW14359 8216991 YP_003078313.1 CDS zwf NC_013008.1 2441945 2443420 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2441945..2443420) Escherichia coli O157:H7 str. TW14359 8216992 YP_003078314.1 CDS yebK NC_013008.1 2443758 2444627 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2443758..2444627 Escherichia coli O157:H7 str. TW14359 8216993 YP_003078315.1 CDS pykA NC_013008.1 2444755 2446197 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2444755..2446197 Escherichia coli O157:H7 str. TW14359 8216994 YP_003078316.1 CDS lpxM NC_013008.1 2446328 2447299 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2446328..2447299) Escherichia coli O157:H7 str. TW14359 8216995 YP_003078317.1 CDS yebA NC_013008.1 2447419 2448741 R hypothetical protein complement(2447419..2448741) Escherichia coli O157:H7 str. TW14359 8216996 YP_003078318.1 CDS znuA NC_013008.1 2448757 2449689 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component complement(2448757..2449689) Escherichia coli O157:H7 str. TW14359 8216997 YP_003078319.1 CDS znuC NC_013008.1 2449768 2450523 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2449768..2450523 Escherichia coli O157:H7 str. TW14359 8216998 YP_003078320.1 CDS znuB NC_013008.1 2450520 2451305 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 2450520..2451305 Escherichia coli O157:H7 str. TW14359 8216999 YP_003078321.1 CDS ruvB NC_013008.1 2451551 2452561 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2451551..2452561) Escherichia coli O157:H7 str. TW14359 8217000 YP_003078322.1 CDS ruvA NC_013008.1 2452570 2453181 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2452570..2453181) Escherichia coli O157:H7 str. TW14359 8217001 YP_003078323.1 CDS yebB NC_013008.1 2453456 2454058 D hypothetical protein 2453456..2454058 Escherichia coli O157:H7 str. TW14359 8217002 YP_003078324.1 CDS ruvC NC_013008.1 2454060 2454581 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2454060..2454581) Escherichia coli O157:H7 str. TW14359 8217003 YP_003078325.1 CDS yebC NC_013008.1 2454616 2455356 R hypothetical protein complement(2454616..2455356) Escherichia coli O157:H7 str. TW14359 8217004 YP_003078326.1 CDS ntpA NC_013008.1 2455385 2455837 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2455385..2455837) Escherichia coli O157:H7 str. TW14359 8217005 YP_003078327.1 CDS aspS NC_013008.1 2455955 2457727 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2455955..2457727) Escherichia coli O157:H7 str. TW14359 8217006 YP_003078328.1 CDS yecD NC_013008.1 2458037 2458603 D hypothetical protein 2458037..2458603 Escherichia coli O157:H7 str. TW14359 8217007 YP_003078329.1 CDS yecE NC_013008.1 2458600 2459418 D hypothetical protein 2458600..2459418 Escherichia coli O157:H7 str. TW14359 8217008 YP_003078330.1 CDS yecN NC_013008.1 2459471 2459866 D inner membrane protein 2459471..2459866 Escherichia coli O157:H7 str. TW14359 8217009 YP_003078331.1 CDS cmoA NC_013008.1 2459907 2460650 D tRNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase 2459907..2460650 Escherichia coli O157:H7 str. TW14359 8217010 YP_003078332.1 CDS cmoB NC_013008.1 2460647 2461618 D tRNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase 2460647..2461618 Escherichia coli O157:H7 str. TW14359 8217011 YP_003078333.1 CDS torZ NC_013008.1 2461783 2464212 R trimethylamine N-oxide reductase system III, catalytic subunit complement(2461783..2464212) Escherichia coli O157:H7 str. TW14359 8217012 YP_003078334.1 CDS torY NC_013008.1 2464237 2465337 R TMAO reductase III (TorYZ), cytochrome c-type subunit complement(2464237..2465337) Escherichia coli O157:H7 str. TW14359 8217013 YP_003078335.1 CDS cutC NC_013008.1 2465725 2466471 R copper homeostasis protein CutC complement(2465725..2466471) Escherichia coli O157:H7 str. TW14359 8217014 YP_003078336.1 CDS yecM NC_013008.1 2466485 2467051 R hypothetical protein complement(2466485..2467051) Escherichia coli O157:H7 str. TW14359 8217015 YP_003078337.1 CDS argS NC_013008.1 2467267 2469000 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2467267..2469000 Escherichia coli O157:H7 str. TW14359 8217016 YP_003078338.1 CDS yecT NC_013008.1 2469177 2469665 D hypothetical protein 2469177..2469665 Escherichia coli O157:H7 str. TW14359 8217017 YP_003078339.1 CDS flhE NC_013008.1 2469785 2470177 R hypothetical protein complement(2469785..2470177) Escherichia coli O157:H7 str. TW14359 8217018 YP_003078340.1 CDS flhA NC_013008.1 2470177 2472255 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2470177..2472255) Escherichia coli O157:H7 str. TW14359 8217019 YP_003078341.1 CDS flhB NC_013008.1 2472248 2473396 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2472248..2473396) Escherichia coli O157:H7 str. TW14359 8217020 YP_003078342.1 CDS cheZ NC_013008.1 2473598 2474242 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2473598..2474242) Escherichia coli O157:H7 str. TW14359 8217021 YP_003078343.1 CDS cheY NC_013008.1 2474253 2474642 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2474253..2474642) Escherichia coli O157:H7 str. TW14359 8217022 YP_003078344.1 CDS cheB NC_013008.1 2474657 2475706 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2474657..2475706) Escherichia coli O157:H7 str. TW14359 8217023 YP_003078345.1 CDS cheR NC_013008.1 2475709 2476569 R methylates the MCP; chemotaxis methyltransferase CheR complement(2475709..2476569) Escherichia coli O157:H7 str. TW14359 8217024 YP_003078346.1 CDS tap NC_013008.1 2476588 2478189 R mediates taxis toward dipeptides; methyl-accepting protein IV complement(2476588..2478189) Escherichia coli O157:H7 str. TW14359 8217025 YP_003078347.1 CDS tar NC_013008.1 2478235 2479896 R methyl-accepting chemotaxis protein II complement(2478235..2479896) Escherichia coli O157:H7 str. TW14359 8217026 YP_003078348.1 CDS cheW NC_013008.1 2480039 2480542 R purine-binding chemotaxis protein complement(2480039..2480542) Escherichia coli O157:H7 str. TW14359 8217027 YP_003078349.1 CDS cheA NC_013008.1 2480563 2482527 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(2480563..2482527) Escherichia coli O157:H7 str. TW14359 8217028 YP_003078350.1 CDS motB NC_013008.1 2482532 2483458 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2482532..2483458) Escherichia coli O157:H7 str. TW14359 8217029 YP_003078351.1 CDS motA NC_013008.1 2483455 2484342 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2483455..2484342) Escherichia coli O157:H7 str. TW14359 8217030 YP_003078352.1 CDS flhC NC_013008.1 2484469 2485047 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2484469..2485047) Escherichia coli O157:H7 str. TW14359 8217031 YP_003078353.1 CDS flhD NC_013008.1 2485050 2485400 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2485050..2485400) Escherichia coli O157:H7 str. TW14359 8217032 YP_003078355.1 CDS yecG NC_013008.1 2486180 2486608 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2486180..2486608 Escherichia coli O157:H7 str. TW14359 8217034 YP_003078356.1 CDS otsA NC_013008.1 2486615 2488039 R trehalose-6-phosphate synthase complement(2486615..2488039) Escherichia coli O157:H7 str. TW14359 8217035 YP_003078357.1 CDS otsB NC_013008.1 2488014 2488814 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2488014..2488814) Escherichia coli O157:H7 str. TW14359 8217036 YP_003078358.1 CDS araH NC_013008.1 2488981 2489970 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(2488981..2489970) Escherichia coli O157:H7 str. TW14359 8217037 YP_003078359.1 CDS araG NC_013008.1 2489982 2491496 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2489982..2491496) Escherichia coli O157:H7 str. TW14359 8217038 YP_003078360.1 CDS araF NC_013008.1 2491566 2492555 R L-arabinose-binding periplasmic protein complement(2491566..2492555) Escherichia coli O157:H7 str. TW14359 8217039 YP_003078361.1 CDS yecI NC_013008.1 2493352 2493855 D ferritin-like protein 2493352..2493855 Escherichia coli O157:H7 str. TW14359 8217040 YP_003078362.1 CDS yecJ NC_013008.1 2493935 2494186 R hypothetical protein complement(2493935..2494186) Escherichia coli O157:H7 str. TW14359 8217041 YP_003078363.1 CDS ECSP_2476 NC_013008.1 2494298 2494444 D hypothetical protein 2494298..2494444 Escherichia coli O157:H7 str. TW14359 8217042 YP_003078364.1 CDS yecR NC_013008.1 2494649 2494972 D hypothetical protein 2494649..2494972 Escherichia coli O157:H7 str. TW14359 8217043 YP_003078365.1 CDS ftn NC_013008.1 2495143 2495640 D cytoplasmic iron storage protein; ferritin 2495143..2495640 Escherichia coli O157:H7 str. TW14359 8217044 YP_003078366.1 CDS yecH NC_013008.1 2495677 2495916 R hypothetical protein complement(2495677..2495916) Escherichia coli O157:H7 str. TW14359 8217045 YP_003078367.1 CDS tyrP NC_013008.1 2496108 2497319 D tyrosine transporter 2496108..2497319 Escherichia coli O157:H7 str. TW14359 8217046 YP_003078368.1 CDS yecA NC_013008.1 2497381 2498046 R hypothetical protein complement(2497381..2498046) Escherichia coli O157:H7 str. TW14359 8217047 YP_003078369.1 CDS intT NC_013008.1 2498403 2499404 R integrase for prophage CP-933T complement(2498403..2499404) Escherichia coli O157:H7 str. TW14359 8217048 YP_003078370.1 CDS ECSP_2483 NC_013008.1 2499410 2499757 R hypothetical protein complement(2499410..2499757) Escherichia coli O157:H7 str. TW14359 8217049 YP_003078371.1 CDS ECSP_2484 NC_013008.1 2499787 2500437 R hypothetical protein complement(2499787..2500437) Escherichia coli O157:H7 str. TW14359 8217050 YP_003078372.1 CDS ECSP_2485 NC_013008.1 2500453 2500857 R hypothetical protein complement(2500453..2500857) Escherichia coli O157:H7 str. TW14359 8217051 YP_003078373.1 CDS coxT NC_013008.1 2501156 2501359 D prophage regulator CP-933T 2501156..2501359 Escherichia coli O157:H7 str. TW14359 8217052 YP_003078374.1 CDS ECSP_2487 NC_013008.1 2501381 2501731 D hypothetical protein 2501381..2501731 Escherichia coli O157:H7 str. TW14359 8217053 YP_003078375.1 CDS ECSP_2488 NC_013008.1 2501742 2502020 D hypothetical protein 2501742..2502020 Escherichia coli O157:H7 str. TW14359 8217054 YP_003078376.1 CDS ECSP_2489 NC_013008.1 2502032 2502274 D hypothetical protein 2502032..2502274 Escherichia coli O157:H7 str. TW14359 8217055 YP_003078377.1 CDS ECSP_2490 NC_013008.1 2502477 2502893 D hypothetical protein 2502477..2502893 Escherichia coli O157:H7 str. TW14359 8217056 YP_003078378.1 CDS ECSP_2491 NC_013008.1 2503380 2503679 D hypothetical protein 2503380..2503679 Escherichia coli O157:H7 str. TW14359 8217057 YP_003078379.1 CDS ECSP_2492 NC_013008.1 2503691 2504308 D hypothetical protein 2503691..2504308 Escherichia coli O157:H7 str. TW14359 8217058 YP_003078380.1 CDS ECSP_2493 NC_013008.1 2504305 2504670 D hypothetical protein 2504305..2504670 Escherichia coli O157:H7 str. TW14359 8217059 YP_003078381.1 CDS ECSP_2494 NC_013008.1 2504677 2507499 D replication protein for prophage CP-933T 2504677..2507499 Escherichia coli O157:H7 str. TW14359 8217060 YP_003078382.1 CDS ECSP_2495 NC_013008.1 2507576 2508535 D stability/partitioning protein encoded within prophage CP-933T 2507576..2508535 Escherichia coli O157:H7 str. TW14359 8217061 YP_003078383.1 CDS ECSP_2496 NC_013008.1 2508540 2508854 D stability/partitioning protein encoded within CP-933T 2508540..2508854 Escherichia coli O157:H7 str. TW14359 8217062 YP_003078384.1 CDS ECSP_2497 NC_013008.1 2508874 2509563 R transposase complement(2508874..2509563) Escherichia coli O157:H7 str. TW14359 8217063 YP_003078385.1 CDS ECSP_2498 NC_013008.1 2509563 2509889 R transposase complement(2509563..2509889) Escherichia coli O157:H7 str. TW14359 8217064 YP_003078386.1 CDS ECSP_2499 NC_013008.1 2510060 2510476 D tail fiber assembly protein of prophage CP-933T 2510060..2510476 Escherichia coli O157:H7 str. TW14359 8217065 YP_003078387.1 CDS ECSP_2500 NC_013008.1 2510520 2511092 R serine acetlyltransferase of prophage CP-933T complement(2510520..2511092) Escherichia coli O157:H7 str. TW14359 8217066 YP_003078388.1 CDS ECSP_2501 NC_013008.1 2511249 2511737 R tail fiber protein of prophage CP-933T complement(2511249..2511737) Escherichia coli O157:H7 str. TW14359 8217067 YP_003078389.1 CDS ECSP_2503 NC_013008.1 2514540 2514695 R tail fiber protein component of prophage CP-933T complement(2514540..2514695) Escherichia coli O157:H7 str. TW14359 8217069 YP_003078390.1 CDS ECSP_2504 NC_013008.1 2514704 2515069 R hypothetical protein complement(2514704..2515069) Escherichia coli O157:H7 str. TW14359 8217070 YP_003078391.1 CDS ECSP_2505 NC_013008.1 2515124 2515636 R tail fiber component of prophage CP-933T complement(2515124..2515636) Escherichia coli O157:H7 str. TW14359 8217071 YP_003078392.1 CDS ECSP_2506 NC_013008.1 2515636 2516820 R tail sheath protein of prophage CP-933T complement(2515636..2516820) Escherichia coli O157:H7 str. TW14359 8217072 YP_003078393.1 CDS ECSP_2507 NC_013008.1 2516948 2517301 D tail assembly protein of prophage CP-933T 2516948..2517301 Escherichia coli O157:H7 str. TW14359 8217073 YP_003078394.1 CDS ECSP_2508 NC_013008.1 2517252 2518181 R transposase, IS30 complement(2517252..2518181) Escherichia coli O157:H7 str. TW14359 8217074 YP_003078395.1 CDS ECSP_2509 NC_013008.1 2518278 2518604 D transposase 2518278..2518604 Escherichia coli O157:H7 str. TW14359 8217075 YP_003078396.1 CDS ECSP_2510 NC_013008.1 2518604 2519491 D transposase, IS1203 2518604..2519491 Escherichia coli O157:H7 str. TW14359 8217076 YP_003078397.1 CDS ECSP_2511 NC_013008.1 2519531 2519677 R hypothetical protein complement(2519531..2519677) Escherichia coli O157:H7 str. TW14359 8217077 YP_003078398.1 CDS ECSP_2512 NC_013008.1 2519858 2520250 R hypothetical protein complement(2519858..2520250) Escherichia coli O157:H7 str. TW14359 8217078 YP_003078399.1 CDS pgsA NC_013008.1 2521131 2521679 R phosphatidylglycerophosphate synthetase complement(2521131..2521679) Escherichia coli O157:H7 str. TW14359 8217082 YP_003078400.1 CDS uvrC NC_013008.1 2521736 2523568 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2521736..2523568) Escherichia coli O157:H7 str. TW14359 8217083 YP_003078401.1 CDS uvrY NC_013008.1 2523565 2524221 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2523565..2524221) Escherichia coli O157:H7 str. TW14359 8217084 YP_003078402.1 CDS yecF NC_013008.1 2524680 2524904 D hypothetical protein 2524680..2524904 Escherichia coli O157:H7 str. TW14359 8217085 YP_003078403.1 CDS sdiA NC_013008.1 2524972 2525694 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2524972..2525694) Escherichia coli O157:H7 str. TW14359 8217086 YP_003078404.1 CDS yecC NC_013008.1 2525924 2526676 R amino-acid ABC transporter ATP-binding protein YecC complement(2525924..2526676) Escherichia coli O157:H7 str. TW14359 8217087 YP_003078405.1 CDS yecS NC_013008.1 2526673 2527341 R ABC transporter membrane protein complement(2526673..2527341) Escherichia coli O157:H7 str. TW14359 8217088 YP_003078406.1 CDS dcyD NC_013008.1 2527356 2528342 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2527356..2528342) Escherichia coli O157:H7 str. TW14359 8217089 YP_003078407.1 CDS fliY NC_013008.1 2528447 2529247 R cystine transporter subunit complement(2528447..2529247) Escherichia coli O157:H7 str. TW14359 8217090 YP_003078408.1 CDS fliZ NC_013008.1 2529335 2529886 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2529335..2529886) Escherichia coli O157:H7 str. TW14359 8217091 YP_003078409.1 CDS fliA NC_013008.1 2529932 2530651 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2529932..2530651) Escherichia coli O157:H7 str. TW14359 8217092 YP_003078410.1 CDS ECSP_2527 NC_013008.1 2530725 2530844 D hypothetical protein 2530725..2530844 Escherichia coli O157:H7 str. TW14359 8217093 YP_003078411.1 CDS fliC NC_013008.1 2530971 2532728 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2530971..2532728) Escherichia coli O157:H7 str. TW14359 8217094 YP_003078412.1 CDS fliD NC_013008.1 2532994 2534391 D involved in flagellin assembly; flagellar capping protein 2532994..2534391 Escherichia coli O157:H7 str. TW14359 8217095 YP_003078413.1 CDS fliS NC_013008.1 2534416 2534826 D flagellin specific chaperone; flagellar protein FliS 2534416..2534826 Escherichia coli O157:H7 str. TW14359 8217096 YP_003078414.1 CDS fliT NC_013008.1 2534826 2535191 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2534826..2535191 Escherichia coli O157:H7 str. TW14359 8217097 YP_003078415.1 CDS amyA NC_013008.1 2535269 2536756 D converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2535269..2536756 Escherichia coli O157:H7 str. TW14359 8217098 YP_003078416.1 CDS yedD NC_013008.1 2536790 2537203 R hypothetical protein complement(2536790..2537203) Escherichia coli O157:H7 str. TW14359 8217099 YP_003078417.1 CDS yedE NC_013008.1 2537390 2538595 D inner membrane protein 2537390..2538595 Escherichia coli O157:H7 str. TW14359 8217100 YP_003078418.1 CDS yedF NC_013008.1 2538592 2538825 D hypothetical protein 2538592..2538825 Escherichia coli O157:H7 str. TW14359 8217101 YP_003078419.1 CDS yedK NC_013008.1 2538934 2539602 D hypothetical protein 2538934..2539602 Escherichia coli O157:H7 str. TW14359 8217102 YP_003078420.1 CDS yedL NC_013008.1 2539713 2540192 D acyltransferase 2539713..2540192 Escherichia coli O157:H7 str. TW14359 8217103 YP_003078421.1 CDS espR3 NC_013008.1 2540330 2541469 R non-LEE-encoded type III effector complement(2540330..2541469) Escherichia coli O157:H7 str. TW14359 8217104 YP_003078422.1 CDS ECSP_2539 NC_013008.1 2541851 2542150 D hypothetical protein 2541851..2542150 Escherichia coli O157:H7 str. TW14359 8217105 YP_003078423.1 CDS espR4 NC_013008.1 2542288 2543427 R non-LEE-encoded type III effector complement(2542288..2543427) Escherichia coli O157:H7 str. TW14359 8217106 YP_003078424.1 CDS fliE NC_013008.1 2543776 2544090 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2543776..2544090) Escherichia coli O157:H7 str. TW14359 8217107 YP_003078425.1 CDS fliF NC_013008.1 2544305 2545963 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2544305..2545963 Escherichia coli O157:H7 str. TW14359 8217108 YP_003078426.1 CDS fliG NC_013008.1 2545956 2546951 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2545956..2546951 Escherichia coli O157:H7 str. TW14359 8217109 YP_003078427.1 CDS fliH NC_013008.1 2546944 2547630 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2546944..2547630 Escherichia coli O157:H7 str. TW14359 8217110 YP_003078428.1 CDS fliI NC_013008.1 2547692 2549065 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2547692..2549065 Escherichia coli O157:H7 str. TW14359 8217111 YP_003078429.1 CDS fliJ NC_013008.1 2549084 2549527 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2549084..2549527 Escherichia coli O157:H7 str. TW14359 8217112 YP_003078430.1 CDS fliK NC_013008.1 2549524 2550651 D flagellar hook-length control protein 2549524..2550651 Escherichia coli O157:H7 str. TW14359 8217113 YP_003078431.1 CDS fliL NC_013008.1 2550756 2551220 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2550756..2551220 Escherichia coli O157:H7 str. TW14359 8217114 YP_003078432.1 CDS fliM NC_013008.1 2551225 2552229 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2551225..2552229 Escherichia coli O157:H7 str. TW14359 8217115 YP_003078433.1 CDS fliN NC_013008.1 2552226 2552639 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2552226..2552639 Escherichia coli O157:H7 str. TW14359 8217116 YP_003078434.1 CDS fliO NC_013008.1 2552642 2553007 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2552642..2553007 Escherichia coli O157:H7 str. TW14359 8217117 YP_003078435.1 CDS fliP NC_013008.1 2553007 2553744 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2553007..2553744 Escherichia coli O157:H7 str. TW14359 8217118 YP_003078436.1 CDS fliQ NC_013008.1 2553754 2554023 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2553754..2554023 Escherichia coli O157:H7 str. TW14359 8217119 YP_003078437.1 CDS fliR NC_013008.1 2554031 2554816 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2554031..2554816 Escherichia coli O157:H7 str. TW14359 8217120 YP_003078438.1 CDS rcsA NC_013008.1 2555106 2555729 D DNA-binding transcriptional activator, co-regulator with RcsB 2555106..2555729 Escherichia coli O157:H7 str. TW14359 8217121 YP_003078439.1 CDS dsrB NC_013008.1 2555773 2555961 R hypothetical protein complement(2555773..2555961) Escherichia coli O157:H7 str. TW14359 8217122 YP_003078440.1 CDS yodD NC_013008.1 2556124 2556351 D hypothetical protein 2556124..2556351 Escherichia coli O157:H7 str. TW14359 8217123 YP_003078441.1 CDS ECSP_2558 NC_013008.1 2556397 2556507 D hypothetical protein 2556397..2556507 Escherichia coli O157:H7 str. TW14359 8217124 YP_003078442.1 CDS yedP NC_013008.1 2556649 2557464 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2556649..2557464 Escherichia coli O157:H7 str. TW14359 8217125 YP_003078443.1 CDS yedQ NC_013008.1 2557461 2559155 R diguanylate cyclase complement(2557461..2559155) Escherichia coli O157:H7 str. TW14359 8217126 YP_003078444.1 CDS yodC NC_013008.1 2559326 2559508 R hypothetical protein complement(2559326..2559508) Escherichia coli O157:H7 str. TW14359 8217127 YP_003078445.1 CDS yedI NC_013008.1 2559587 2560504 R hypothetical protein complement(2559587..2560504) Escherichia coli O157:H7 str. TW14359 8217128 YP_003078446.1 CDS yedA NC_013008.1 2560677 2561597 D hypothetical protein 2560677..2561597 Escherichia coli O157:H7 str. TW14359 8217129 YP_003078447.1 CDS vsr NC_013008.1 2561586 2562056 R DNA mismatch endonuclease of very short patch repair complement(2561586..2562056) Escherichia coli O157:H7 str. TW14359 8217130 YP_003078448.1 CDS dcm NC_013008.1 2562037 2563455 R DNA cytosine methylase complement(2562037..2563455) Escherichia coli O157:H7 str. TW14359 8217131 YP_003078449.1 CDS yedJ NC_013008.1 2563522 2564217 R hypothetical protein complement(2563522..2564217) Escherichia coli O157:H7 str. TW14359 8217132 YP_003078450.1 CDS yedR NC_013008.1 2564313 2564621 R inner membrane protein complement(2564313..2564621) Escherichia coli O157:H7 str. TW14359 8217133 YP_003078451.1 CDS ECSP_2568 NC_013008.1 2564804 2564917 D hypothetical protein 2564804..2564917 Escherichia coli O157:H7 str. TW14359 8217134 YP_003078452.1 CDS ECSP_2569 NC_013008.1 2565188 2565832 D outer membrane protein 2565188..2565832 Escherichia coli O157:H7 str. TW14359 8217135 YP_003078453.1 CDS ECSP_2570 NC_013008.1 2565799 2566374 D outer membrane protein 2565799..2566374 Escherichia coli O157:H7 str. TW14359 8217136 YP_003078454.1 CDS ECSP_2571 NC_013008.1 2566583 2566786 R hypothetical protein complement(2566583..2566786) Escherichia coli O157:H7 str. TW14359 8217137 YP_003078455.1 CDS ECSP_2572 NC_013008.1 2566802 2566945 D hypothetical protein 2566802..2566945 Escherichia coli O157:H7 str. TW14359 8217138 YP_003078456.1 CDS hchA NC_013008.1 2566966 2567817 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2566966..2567817 Escherichia coli O157:H7 str. TW14359 8217139 YP_003078457.1 CDS yedV NC_013008.1 2567925 2569283 R sensory kinase in two-component regulatory system with YedW complement(2567925..2569283) Escherichia coli O157:H7 str. TW14359 8217140 YP_003078458.1 CDS yedW NC_013008.1 2569283 2569954 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2569283..2569954) Escherichia coli O157:H7 str. TW14359 8217141 YP_003078459.1 CDS yedX NC_013008.1 2570087 2570500 D hypothetical protein 2570087..2570500 Escherichia coli O157:H7 str. TW14359 8217142 YP_003078460.1 CDS yedY NC_013008.1 2570608 2571612 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2570608..2571612 Escherichia coli O157:H7 str. TW14359 8217143 YP_003078461.1 CDS yedZ NC_013008.1 2571613 2572248 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2571613..2572248 Escherichia coli O157:H7 str. TW14359 8217144 YP_003078462.1 CDS yodA NC_013008.1 2572505 2573155 D hypothetical protein 2572505..2573155 Escherichia coli O157:H7 str. TW14359 8217145 YP_003078463.1 CDS ECSP_2580 NC_013008.1 2573265 2573414 D hypothetical protein 2573265..2573414 Escherichia coli O157:H7 str. TW14359 8217146 YP_003078464.1 CDS yodB NC_013008.1 2573498 2574028 D cytochrome 2573498..2574028 Escherichia coli O157:H7 str. TW14359 8217147 YP_003078465.1 CDS ECSP_2582 NC_013008.1 2574598 2574957 D hypothetical protein 2574598..2574957 Escherichia coli O157:H7 str. TW14359 8217148 YP_003078466.1 CDS espJ NC_013008.1 2575299 2575817 D translocated type III secretion system effector 2575299..2575817 Escherichia coli O157:H7 str. TW14359 8217149 YP_003078467.1 CDS tccP NC_013008.1 2576142 2577155 D Tir-cytoskeleton coupling protein (TccP) 2576142..2577155 Escherichia coli O157:H7 str. TW14359 8217150 YP_003078468.1 CDS ECSP_2585 NC_013008.1 2577281 2577550 R tail fiber protein complement(2577281..2577550) Escherichia coli O157:H7 str. TW14359 8217151 YP_003078469.1 CDS ECSP_2586 NC_013008.1 2577552 2578865 R tail fiber protein complement(2577552..2578865) Escherichia coli O157:H7 str. TW14359 8217152 YP_003078470.1 CDS ECSP_2587 NC_013008.1 2578930 2579529 R Ail/Lom family protein complement(2578930..2579529) Escherichia coli O157:H7 str. TW14359 8217153 YP_003078471.1 CDS ECSP_2589 NC_013008.1 2583317 2583895 R tail assembly protein complement(2583317..2583895) Escherichia coli O157:H7 str. TW14359 8217155 YP_003078472.1 CDS ECSP_2590 NC_013008.1 2583892 2584527 R tail fiber component complement(2583892..2584527) Escherichia coli O157:H7 str. TW14359 8217156 YP_003078473.1 CDS ECSP_2591 NC_013008.1 2584646 2585344 R minor tail protein L complement(2584646..2585344) Escherichia coli O157:H7 str. TW14359 8217157 YP_003078474.1 CDS ECSP_2592 NC_013008.1 2585344 2585673 R phage minor tail protein complement(2585344..2585673) Escherichia coli O157:H7 str. TW14359 8217158 YP_003078475.1 CDS ECSP_2593 NC_013008.1 2585670 2588249 R tail length tape measure protein complement(2585670..2588249) Escherichia coli O157:H7 str. TW14359 8217159 YP_003078476.1 CDS ECSP_2594 NC_013008.1 2588230 2588643 R tail component of prophage CP-933R complement(2588230..2588643) Escherichia coli O157:H7 str. TW14359 8217160 YP_003078477.1 CDS ECSP_2595 NC_013008.1 2588670 2589173 R tail component of prophage CP-933R complement(2588670..2589173) Escherichia coli O157:H7 str. TW14359 8217161 YP_003078478.1 CDS ECSP_2596 NC_013008.1 2589115 2589777 R tail component of prophage CP-933R complement(2589115..2589777) Escherichia coli O157:H7 str. TW14359 8217162 YP_003078479.1 CDS ECSP_2597 NC_013008.1 2589837 2590103 R capsid structural protein of prophage CP-933R complement(2589837..2590103) Escherichia coli O157:H7 str. TW14359 8217163 YP_003078480.1 CDS ECSP_2598 NC_013008.1 2590161 2590508 R capsid protein of prophage CP-933R complement(2590161..2590508) Escherichia coli O157:H7 str. TW14359 8217164 YP_003078481.1 CDS ECSP_2599 NC_013008.1 2590545 2592050 R capsid assembly protein of prophage CP-933R complement(2590545..2592050) Escherichia coli O157:H7 str. TW14359 8217165 YP_003078482.1 CDS ECSP_2600 NC_013008.1 2592040 2593632 R capsid protein of prophage CP-933R complement(2592040..2593632) Escherichia coli O157:H7 str. TW14359 8217166 YP_003078483.1 CDS ECSP_2601 NC_013008.1 2593629 2593769 R DNA packaging protein of prophage CP-933R complement(2593629..2593769) Escherichia coli O157:H7 str. TW14359 8217167 YP_003078484.1 CDS ECSP_2602 NC_013008.1 2593819 2595510 R DNA packaging protein of prophage CP-933R; terminase large subunit complement(2593819..2595510) Escherichia coli O157:H7 str. TW14359 8217168 YP_003078485.1 CDS ECSP_2603 NC_013008.1 2595720 2596229 R DNA packaging protein of prophage CP-933R; terminase small subunit complement(2595720..2596229) Escherichia coli O157:H7 str. TW14359 8217169 YP_003078486.1 CDS ECSP_2604 NC_013008.1 2596624 2596848 D hypothetical protein 2596624..2596848 Escherichia coli O157:H7 str. TW14359 8217170 YP_003078487.1 CDS ECSP_2605 NC_013008.1 2597247 2597360 D hypothetical protein 2597247..2597360 Escherichia coli O157:H7 str. TW14359 8217171 YP_003078488.1 CDS ECSP_2606 NC_013008.1 2597486 2597626 R hypothetical protein complement(2597486..2597626) Escherichia coli O157:H7 str. TW14359 8217172 YP_003078489.1 CDS ECSP_2607 NC_013008.1 2597709 2598176 R endopeptidase Rz of prophage CP-933R complement(2597709..2598176) Escherichia coli O157:H7 str. TW14359 8217173 YP_003078490.1 CDS ECSP_2608 NC_013008.1 2598328 2598510 R hypothetical protein complement(2598328..2598510) Escherichia coli O157:H7 str. TW14359 8217174 YP_003078491.1 CDS ECSP_2609 NC_013008.1 2598666 2599199 R lysozyme R of prophage CP-933R complement(2598666..2599199) Escherichia coli O157:H7 str. TW14359 8217175 YP_003078492.1 CDS ECSP_2610 NC_013008.1 2599250 2599594 R hypothetical protein complement(2599250..2599594) Escherichia coli O157:H7 str. TW14359 8217176 YP_003078493.1 CDS ECSP_2611 NC_013008.1 2599599 2599805 R hypothetical protein complement(2599599..2599805) Escherichia coli O157:H7 str. TW14359 8217177 YP_003078494.1 CDS ECSP_2612 NC_013008.1 2600125 2600451 D transposase 2600125..2600451 Escherichia coli O157:H7 str. TW14359 8217178 YP_003078495.1 CDS ECSP_2613 NC_013008.1 2600448 2601338 D transposase 2600448..2601338 Escherichia coli O157:H7 str. TW14359 8217179 YP_003078496.1 CDS ECSP_2614 NC_013008.1 2601420 2603270 R hypothetical protein complement(2601420..2603270) Escherichia coli O157:H7 str. TW14359 8217180 YP_003078497.1 CDS ECSP_2615 NC_013008.1 2603584 2603751 R hypothetical protein complement(2603584..2603751) Escherichia coli O157:H7 str. TW14359 8217181 YP_003078498.1 CDS ECSP_2616 NC_013008.1 2603748 2604176 R hypothetical protein complement(2603748..2604176) Escherichia coli O157:H7 str. TW14359 8217182 YP_003078499.1 CDS ECSP_2620 NC_013008.1 2604810 2605499 R antiterminator Q-like protein of prophage CP-933U complement(2604810..2605499) Escherichia coli O157:H7 str. TW14359 8217186 YP_003078500.1 CDS ECSP_2621 NC_013008.1 2605496 2605855 R endonuclease encoded within prophage CP-933U complement(2605496..2605855) Escherichia coli O157:H7 str. TW14359 8217187 YP_003078501.1 CDS ECSP_2622 NC_013008.1 2605868 2606917 R hypothetical protein complement(2605868..2606917) Escherichia coli O157:H7 str. TW14359 8217188 YP_003078502.1 CDS ECSP_2623 NC_013008.1 2606919 2607197 R hypothetical protein complement(2606919..2607197) Escherichia coli O157:H7 str. TW14359 8217189 YP_003078503.1 CDS ECSP_2624 NC_013008.1 2607764 2607913 R hypothetical protein complement(2607764..2607913) Escherichia coli O157:H7 str. TW14359 8217190 YP_003078504.1 CDS ECSP_2625 NC_013008.1 2607978 2608541 R hypothetical protein complement(2607978..2608541) Escherichia coli O157:H7 str. TW14359 8217191 YP_003078505.1 CDS ECSP_2626 NC_013008.1 2608668 2608979 R hypothetical protein complement(2608668..2608979) Escherichia coli O157:H7 str. TW14359 8217192 YP_003078506.1 CDS ECSP_2627 NC_013008.1 2609161 2609517 R hypothetical protein complement(2609161..2609517) Escherichia coli O157:H7 str. TW14359 8217193 YP_003078507.1 CDS ECSP_2628 NC_013008.1 2609760 2610458 R hypothetical protein complement(2609760..2610458) Escherichia coli O157:H7 str. TW14359 8217194 YP_003078508.1 CDS ECSP_2629 NC_013008.1 2610493 2610915 R hypothetical protein complement(2610493..2610915) Escherichia coli O157:H7 str. TW14359 8217195 YP_003078509.1 CDS ECSP_2630 NC_013008.1 2610947 2611984 R hypothetical protein complement(2610947..2611984) Escherichia coli O157:H7 str. TW14359 8217196 YP_003078510.1 CDS ECSP_2631 NC_013008.1 2612053 2612478 R hypothetical protein complement(2612053..2612478) Escherichia coli O157:H7 str. TW14359 8217197 YP_003078511.1 CDS ECSP_2632 NC_013008.1 2612797 2613444 D repressor protein of prophage CP-933U 2612797..2613444 Escherichia coli O157:H7 str. TW14359 8217198 YP_003078512.1 CDS ECSP_2633 NC_013008.1 2613719 2613871 D hypothetical protein 2613719..2613871 Escherichia coli O157:H7 str. TW14359 8217199 YP_003078513.1 CDS ECSP_2634 NC_013008.1 2614352 2614540 D hypothetical protein 2614352..2614540 Escherichia coli O157:H7 str. TW14359 8217200 YP_003078514.1 CDS ECSP_2635 NC_013008.1 2614537 2614725 D hypothetical protein 2614537..2614725 Escherichia coli O157:H7 str. TW14359 8217201 YP_003078515.1 CDS exoU NC_013008.1 2614821 2617292 D exodeoxyribonuclease VIII of prophage CP-933U 2614821..2617292 Escherichia coli O157:H7 str. TW14359 8217202 YP_003078516.1 CDS intU NC_013008.1 2617554 2618633 D integrase for prophage CP-933U 2617554..2618633 Escherichia coli O157:H7 str. TW14359 8217203 YP_003078517.1 CDS mtfA NC_013008.1 2618825 2619622 D hypothetical protein 2618825..2619622 Escherichia coli O157:H7 str. TW14359 8217205 YP_003078518.1 CDS yeeJ NC_013008.1 2620085 2628094 D adhesin 2620085..2628094 Escherichia coli O157:H7 str. TW14359 8217207 YP_003078519.1 CDS ECSP_2642 NC_013008.1 2628356 2629408 R hypothetical protein complement(2628356..2629408) Escherichia coli O157:H7 str. TW14359 8217208 YP_003078520.1 CDS shiA NC_013008.1 2629722 2631038 D shikimate transporter 2629722..2631038 Escherichia coli O157:H7 str. TW14359 8217209 YP_003078521.1 CDS amn NC_013008.1 2631140 2632594 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2631140..2632594 Escherichia coli O157:H7 str. TW14359 8217210 YP_003078522.1 CDS yeeN NC_013008.1 2632937 2633653 D hypothetical protein 2632937..2633653 Escherichia coli O157:H7 str. TW14359 8217211 YP_003078523.1 CDS ECSP_2646 NC_013008.1 2633698 2633880 R hypothetical protein complement(2633698..2633880) Escherichia coli O157:H7 str. TW14359 8217212 YP_003078524.1 CDS ECSP_2647 NC_013008.1 2633947 2634063 D hypothetical protein 2633947..2634063 Escherichia coli O157:H7 str. TW14359 8217213 YP_003078525.1 CDS ECSP_2649 NC_013008.1 2634279 2635766 R hypothetical protein complement(2634279..2635766) Escherichia coli O157:H7 str. TW14359 8217215 YP_003078526.1 CDS cbl NC_013008.1 2636040 2636990 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2636040..2636990) Escherichia coli O157:H7 str. TW14359 8217217 YP_003078527.1 CDS nac NC_013008.1 2637092 2638009 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2637092..2638009) Escherichia coli O157:H7 str. TW14359 8217218 YP_003078528.1 CDS ECSP_2653 NC_013008.1 2638197 2638313 D hypothetical protein 2638197..2638313 Escherichia coli O157:H7 str. TW14359 8217219 YP_003078529.1 CDS erfK NC_013008.1 2638466 2639398 R hypothetical protein complement(2638466..2639398) Escherichia coli O157:H7 str. TW14359 8217221 YP_003078530.1 CDS cobT NC_013008.1 2639463 2640542 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2639463..2640542) Escherichia coli O157:H7 str. TW14359 8217222 YP_003078531.1 CDS cobS NC_013008.1 2640554 2641297 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2640554..2641297) Escherichia coli O157:H7 str. TW14359 8217223 YP_003078532.1 CDS cobU NC_013008.1 2641294 2641839 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(2641294..2641839) Escherichia coli O157:H7 str. TW14359 8217224 YP_003078533.1 CDS ECSP_2659 NC_013008.1 2642180 2642581 D transposase, ISEc8 2642180..2642581 Escherichia coli O157:H7 str. TW14359 8217225 YP_003078534.1 CDS ECSP_2660 NC_013008.1 2642578 2642925 D transposase 2642578..2642925 Escherichia coli O157:H7 str. TW14359 8217226 YP_003078535.1 CDS ECSP_2661 NC_013008.1 2642975 2644513 D transposase, ISEc8 2642975..2644513 Escherichia coli O157:H7 str. TW14359 8217227 YP_003078536.1 CDS ECSP_2662 NC_013008.1 2644754 2644918 R hypothetical protein complement(2644754..2644918) Escherichia coli O157:H7 str. TW14359 8217228 YP_003078537.1 CDS ECSP_2663 NC_013008.1 2645331 2646221 R transposase complement(2645331..2646221) Escherichia coli O157:H7 str. TW14359 8217229 YP_003078538.1 CDS ECSP_2664 NC_013008.1 2646218 2646544 R transposase complement(2646218..2646544) Escherichia coli O157:H7 str. TW14359 8217230 YP_003078539.1 CDS ECSP_2665 NC_013008.1 2647274 2649421 D outer membrane receptor for iron compound or colicin 2647274..2649421 Escherichia coli O157:H7 str. TW14359 8217231 YP_003078540.1 CDS ECSP_2666 NC_013008.1 2649874 2650557 D hypothetical protein 2649874..2650557 Escherichia coli O157:H7 str. TW14359 8217232 YP_003078541.1 CDS ECSP_2667 NC_013008.1 2650554 2651459 D hypothetical protein 2650554..2651459 Escherichia coli O157:H7 str. TW14359 8217233 YP_003078542.1 CDS ECSP_2668 NC_013008.1 2651456 2652526 D hypothetical protein 2651456..2652526 Escherichia coli O157:H7 str. TW14359 8217234 YP_003078543.1 CDS ECSP_2669 NC_013008.1 2652662 2653345 D hypothetical protein 2652662..2653345 Escherichia coli O157:H7 str. TW14359 8217235 YP_003078544.1 CDS ECSP_2670 NC_013008.1 2653361 2653771 D hypothetical protein 2653361..2653771 Escherichia coli O157:H7 str. TW14359 8217236 YP_003078545.1 CDS ECSP_2671 NC_013008.1 2653992 2654813 D hypothetical protein 2653992..2654813 Escherichia coli O157:H7 str. TW14359 8217237 YP_003078546.1 CDS ECSP_2672 NC_013008.1 2654895 2655374 D antirestriction protein 2654895..2655374 Escherichia coli O157:H7 str. TW14359 8217238 YP_003078547.1 CDS ECSP_2673 NC_013008.1 2655389 2655865 D DNA repair protein 2655389..2655865 Escherichia coli O157:H7 str. TW14359 8217239 YP_003078548.1 CDS yeeT NC_013008.1 2655928 2656149 D CP4-44 prophage protein 2655928..2656149 Escherichia coli O157:H7 str. TW14359 8217240 YP_003078549.1 CDS yeeU NC_013008.1 2656223 2656591 D CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 2656223..2656591 Escherichia coli O157:H7 str. TW14359 8217241 YP_003078550.1 CDS yeeV NC_013008.1 2656680 2656943 D CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system 2656680..2656943 Escherichia coli O157:H7 str. TW14359 8217242 YP_003078551.1 CDS yeeW NC_013008.1 2657050 2657244 D CP4-44 prophage protein 2657050..2657244 Escherichia coli O157:H7 str. TW14359 8217243 YP_003078552.1 CDS ECSP_2678 NC_013008.1 2657257 2657370 D hypothetical protein 2657257..2657370 Escherichia coli O157:H7 str. TW14359 8217244 YP_003078553.1 CDS ECSP_2679 NC_013008.1 2657685 2658041 D hypothetical protein 2657685..2658041 Escherichia coli O157:H7 str. TW14359 8217245 YP_003078554.1 CDS yeeX NC_013008.1 2658142 2658471 R hypothetical protein complement(2658142..2658471) Escherichia coli O157:H7 str. TW14359 8217246 YP_003078555.1 CDS yeeA NC_013008.1 2658643 2659701 R hypothetical protein complement(2658643..2659701) Escherichia coli O157:H7 str. TW14359 8217247 YP_003078556.1 CDS sbmC NC_013008.1 2659900 2660373 R DNA gyrase inhibitor complement(2659900..2660373) Escherichia coli O157:H7 str. TW14359 8217248 YP_003078557.1 CDS dacD NC_013008.1 2660492 2661658 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2660492..2661658) Escherichia coli O157:H7 str. TW14359 8217249 YP_003078558.1 CDS ECSP_2684 NC_013008.1 2661819 2661929 D hypothetical protein 2661819..2661929 Escherichia coli O157:H7 str. TW14359 8217250 YP_003078559.1 CDS ECSP_2685 NC_013008.1 2662713 2662997 D hypothetical protein 2662713..2662997 Escherichia coli O157:H7 str. TW14359 8217251 YP_003078560.1 CDS ECSP_2686 NC_013008.1 2662982 2663632 D hypothetical protein 2662982..2663632 Escherichia coli O157:H7 str. TW14359 8217252 YP_003078561.1 CDS ECSP_2687 NC_013008.1 2663856 2664731 R OspB-like virulence factor complement(2663856..2664731) Escherichia coli O157:H7 str. TW14359 8217253 YP_003078562.1 CDS ECSP_2688 NC_013008.1 2664872 2665141 R tail fiber protein complement(2664872..2665141) Escherichia coli O157:H7 str. TW14359 8217254 YP_003078563.1 CDS ECSP_2689 NC_013008.1 2665143 2666456 R side tail fiber protein complement(2665143..2666456) Escherichia coli O157:H7 str. TW14359 8217255 YP_003078564.1 CDS lomU NC_013008.1 2666521 2667120 R opacity protein opA58 complement(2666521..2667120) Escherichia coli O157:H7 str. TW14359 8217256 YP_003078565.1 CDS vhsJ NC_013008.1 2667188 2670667 R host specificity protein J complement(2667188..2670667) Escherichia coli O157:H7 str. TW14359 8217257 YP_003078566.1 CDS ECSP_2692 NC_013008.1 2670906 2671586 R tail assembly protein I complement(2670906..2671586) Escherichia coli O157:H7 str. TW14359 8217258 YP_003078567.1 CDS ECSP_2693 NC_013008.1 2671484 2672221 R tail assembly protein complement(2671484..2672221) Escherichia coli O157:H7 str. TW14359 8217259 YP_003078568.1 CDS ECSP_2694 NC_013008.1 2672276 2673280 R antirepressor-like protein complement(2672276..2673280) Escherichia coli O157:H7 str. TW14359 8217260 YP_003078569.1 CDS ECSP_2695 NC_013008.1 2673270 2673443 R hypothetical protein complement(2673270..2673443) Escherichia coli O157:H7 str. TW14359 8217261 YP_003078570.1 CDS ECSP_2696 NC_013008.1 2673527 2673871 D hypothetical protein 2673527..2673871 Escherichia coli O157:H7 str. TW14359 8217262 YP_003078571.1 CDS ECSP_2698 NC_013008.1 2674614 2674955 R minor tail protein M complement(2674614..2674955) Escherichia coli O157:H7 str. TW14359 8217264 YP_003078572.1 CDS ECSP_2699 NC_013008.1 2674948 2678190 R minor tail protein H complement(2674948..2678190) Escherichia coli O157:H7 str. TW14359 8217265 YP_003078573.1 CDS ECSP_2700 NC_013008.1 2678242 2678523 R phage-tail protein complement(2678242..2678523) Escherichia coli O157:H7 str. TW14359 8217266 YP_003078574.1 CDS ECSP_2701 NC_013008.1 2678547 2678921 R tail assembly chaperone complement(2678547..2678921) Escherichia coli O157:H7 str. TW14359 8217267 YP_003078575.1 CDS ECSP_2702 NC_013008.1 2678927 2679643 R major tail subunit complement(2678927..2679643) Escherichia coli O157:H7 str. TW14359 8217268 YP_003078576.1 CDS ECSP_2703 NC_013008.1 2679702 2680046 R hypothetical protein complement(2679702..2680046) Escherichia coli O157:H7 str. TW14359 8217269 YP_003078577.1 CDS ECSP_2704 NC_013008.1 2680043 2680489 R hypothetical protein complement(2680043..2680489) Escherichia coli O157:H7 str. TW14359 8217270 YP_003078578.1 CDS ECSP_2705 NC_013008.1 2680486 2680836 R bacteriophage head-tail adaptor complement(2680486..2680836) Escherichia coli O157:H7 str. TW14359 8217271 YP_003078579.1 CDS ECSP_2706 NC_013008.1 2680846 2681172 R hypothetical protein complement(2680846..2681172) Escherichia coli O157:H7 str. TW14359 8217272 YP_003078580.1 CDS ECSP_2707 NC_013008.1 2681252 2683753 R portal protein (GP3) complement(2681252..2683753) Escherichia coli O157:H7 str. TW14359 8217273 YP_003078581.1 CDS ECSP_2708 NC_013008.1 2683965 2685902 R major head protein Gp17 complement(2683965..2685902) Escherichia coli O157:H7 str. TW14359 8217274 YP_003078582.1 CDS terL NC_013008.1 2685966 2687627 R phage terminase large subunit complement(2685966..2687627) Escherichia coli O157:H7 str. TW14359 8217275 YP_003078583.1 CDS terS NC_013008.1 2687624 2688187 R PBSX phage terminase small subunit complement(2687624..2688187) Escherichia coli O157:H7 str. TW14359 8217276 YP_003078584.1 CDS ECSP_2711 NC_013008.1 2688251 2688352 R hypothetical protein complement(2688251..2688352) Escherichia coli O157:H7 str. TW14359 8217277 YP_003078585.1 CDS ECSP_2712 NC_013008.1 2688479 2688844 R restriction endonuclease complement(2688479..2688844) Escherichia coli O157:H7 str. TW14359 8217278 YP_003078586.1 CDS ECSP_2713 NC_013008.1 2688886 2689113 D hypothetical protein 2688886..2689113 Escherichia coli O157:H7 str. TW14359 8217279 YP_003078587.1 CDS ECSP_2714 NC_013008.1 2689576 2689833 R hypothetical protein complement(2689576..2689833) Escherichia coli O157:H7 str. TW14359 8217280 YP_003078588.1 CDS kilA NC_013008.1 2689830 2690327 R KilA-N domain family protein complement(2689830..2690327) Escherichia coli O157:H7 str. TW14359 8217281 YP_003078589.1 CDS ECSP_2716 NC_013008.1 2690530 2690967 R Rz lysis family protein complement(2690530..2690967) Escherichia coli O157:H7 str. TW14359 8217282 YP_003078590.1 CDS lys NC_013008.1 2690964 2691461 R phage-related lysozyme complement(2690964..2691461) Escherichia coli O157:H7 str. TW14359 8217283 YP_003078591.1 CDS s NC_013008.1 2691461 2691676 R phage Lysis protein S complement(2691461..2691676) Escherichia coli O157:H7 str. TW14359 8217284 YP_003078592.1 CDS ECSP_2719 NC_013008.1 2691753 2692025 R hypothetical protein complement(2691753..2692025) Escherichia coli O157:H7 str. TW14359 8217285 YP_003078593.1 CDS ECSP_2720 NC_013008.1 2692066 2692245 R hypothetical protein complement(2692066..2692245) Escherichia coli O157:H7 str. TW14359 8217286 YP_003078594.1 CDS ECSP_2721 NC_013008.1 2692382 2694319 R hypothetical protein complement(2692382..2694319) Escherichia coli O157:H7 str. TW14359 8217287 YP_003078595.1 CDS stx2cB NC_013008.1 2695183 2695452 R Shiga-like toxin II subunit B complement(2695183..2695452) Escherichia coli O157:H7 str. TW14359 8217288 YP_003078596.1 CDS stx2A1 NC_013008.1 2695464 2696423 R Shiga-like toxin II subunit A complement(2695464..2696423) Escherichia coli O157:H7 str. TW14359 8217289 YP_003078597.1 CDS ECSP_2727 NC_013008.1 2697073 2697561 R antitermination protein Q complement(2697073..2697561) Escherichia coli O157:H7 str. TW14359 8217293 YP_003078598.1 CDS ECSP_2728 NC_013008.1 2697552 2698223 R serine/threonine protein phosphatase 1 complement(2697552..2698223) Escherichia coli O157:H7 str. TW14359 8217294 YP_003078599.1 CDS ECSP_2729 NC_013008.1 2698220 2698825 R protein ninG complement(2698220..2698825) Escherichia coli O157:H7 str. TW14359 8217295 YP_003078600.1 CDS ECSP_2730 NC_013008.1 2698825 2699547 R DNA-binding protein Roi complement(2698825..2699547) Escherichia coli O157:H7 str. TW14359 8217296 YP_003078601.1 CDS ECSP_2731 NC_013008.1 2699622 2700302 R antirepressor protein ant complement(2699622..2700302) Escherichia coli O157:H7 str. TW14359 8217297 YP_003078602.1 CDS antA NC_013008.1 2700558 2701316 R anti-termination protein complement(2700558..2701316) Escherichia coli O157:H7 str. TW14359 8217298 YP_003078603.1 CDS ECSP_2733 NC_013008.1 2701770 2702297 R DNA methyltransferase complement(2701770..2702297) Escherichia coli O157:H7 str. TW14359 8217299 YP_003078604.1 CDS ECSP_2734 NC_013008.1 2702294 2702740 R recombination protein ninB complement(2702294..2702740) Escherichia coli O157:H7 str. TW14359 8217300 YP_003078605.1 CDS ECSP_2735 NC_013008.1 2702697 2703059 R hypothetical protein complement(2702697..2703059) Escherichia coli O157:H7 str. TW14359 8217301 YP_003078606.1 CDS ECSP_2736 NC_013008.1 2703292 2703570 R hypothetical protein complement(2703292..2703570) Escherichia coli O157:H7 str. TW14359 8217302 YP_003078607.1 CDS ECSP_2737 NC_013008.1 2703641 2705017 R replicative DNA helicase complement(2703641..2705017) Escherichia coli O157:H7 str. TW14359 8217303 YP_003078608.1 CDS ECSP_2738 NC_013008.1 2705014 2705835 R bacteriophage replication protein O complement(2705014..2705835) Escherichia coli O157:H7 str. TW14359 8217304 YP_003078609.1 CDS ECSP_2739 NC_013008.1 2706016 2706312 R regulatory protein CII complement(2706016..2706312) Escherichia coli O157:H7 str. TW14359 8217305 YP_003078610.1 CDS ECSP_2740 NC_013008.1 2706454 2706669 R Cro antirepressor complement(2706454..2706669) Escherichia coli O157:H7 str. TW14359 8217306 YP_003078611.1 CDS ECSP_2741 NC_013008.1 2706745 2707440 D repressor protein CI 2706745..2707440 Escherichia coli O157:H7 str. TW14359 8217307 YP_003078612.1 CDS ECSP_2742 NC_013008.1 2707942 2708463 D hypothetical protein 2707942..2708463 Escherichia coli O157:H7 str. TW14359 8217308 YP_003078613.1 CDS antN NC_013008.1 2709120 2709464 D anti-termination protein N 2709120..2709464 Escherichia coli O157:H7 str. TW14359 8217309 YP_003078614.1 CDS ECSP_2744 NC_013008.1 2709523 2709774 D hypothetical protein 2709523..2709774 Escherichia coli O157:H7 str. TW14359 8217310 YP_003078615.1 CDS ECSP_2745 NC_013008.1 2709957 2710325 D single stranded binding protein 2709957..2710325 Escherichia coli O157:H7 str. TW14359 8217311 YP_003078616.1 CDS kil1 NC_013008.1 2710405 2710674 D host killing protein Kil 2710405..2710674 Escherichia coli O157:H7 str. TW14359 8217312 YP_003078617.1 CDS ECSP_2747 NC_013008.1 2710629 2711045 D host-nuclease inhibitor protein gam 2710629..2711045 Escherichia coli O157:H7 str. TW14359 8217313 YP_003078618.1 CDS bet1 NC_013008.1 2711051 2711836 D recombination protein bet 2711051..2711836 Escherichia coli O157:H7 str. TW14359 8217314 YP_003078619.1 CDS ECSP_2749 NC_013008.1 2712131 2713021 R transposase complement(2712131..2713021) Escherichia coli O157:H7 str. TW14359 8217315 YP_003078620.1 CDS ECSP_2750 NC_013008.1 2713018 2713344 R transposase complement(2713018..2713344) Escherichia coli O157:H7 str. TW14359 8217316 YP_003078621.1 CDS ECSP_2752 NC_013008.1 2713817 2714005 D hypothetical protein 2713817..2714005 Escherichia coli O157:H7 str. TW14359 8217318 YP_003078622.1 CDS ECSP_2753 NC_013008.1 2713978 2714169 D hypothetical protein 2713978..2714169 Escherichia coli O157:H7 str. TW14359 8217319 YP_003078623.1 CDS ECSP_2754 NC_013008.1 2714180 2714461 D hypothetical protein 2714180..2714461 Escherichia coli O157:H7 str. TW14359 8217320 YP_003078624.1 CDS ECSP_2755 NC_013008.1 2714560 2714781 D DnaK suppressor protein 2714560..2714781 Escherichia coli O157:H7 str. TW14359 8217321 YP_003078625.1 CDS ECSP_2756 NC_013008.1 2714778 2715725 D hypothetical protein 2714778..2715725 Escherichia coli O157:H7 str. TW14359 8217322 YP_003078626.1 CDS ECSP_2758 NC_013008.1 2716237 2716593 D hypothetical protein 2716237..2716593 Escherichia coli O157:H7 str. TW14359 8217324 YP_003078627.1 CDS ECSP_2759 NC_013008.1 2716590 2716940 D hypothetical protein 2716590..2716940 Escherichia coli O157:H7 str. TW14359 8217325 YP_003078628.1 CDS ECSP_2760 NC_013008.1 2717128 2717472 D hypothetical protein 2717128..2717472 Escherichia coli O157:H7 str. TW14359 8217326 YP_003078629.1 CDS int NC_013008.1 2717722 2718900 R prophage integrase complement(2717722..2718900) Escherichia coli O157:H7 str. TW14359 8217327 YP_003078630.1 CDS sbcB NC_013008.1 2719082 2720506 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2719082..2720506 Escherichia coli O157:H7 str. TW14359 8217328 YP_003078631.1 CDS yeeD NC_013008.1 2720549 2720776 R hypothetical protein complement(2720549..2720776) Escherichia coli O157:H7 str. TW14359 8217329 YP_003078632.1 CDS yeeE NC_013008.1 2720790 2721848 R inner membrane protein complement(2720790..2721848) Escherichia coli O157:H7 str. TW14359 8217330 YP_003078633.1 CDS yeeF NC_013008.1 2722027 2723385 R amino-acid transporter complement(2722027..2723385) Escherichia coli O157:H7 str. TW14359 8217331 YP_003078634.1 CDS yeeY NC_013008.1 2723652 2724581 R DNA-binding transcriptional regulator complement(2723652..2724581) Escherichia coli O157:H7 str. TW14359 8217332 YP_003078635.1 CDS yeeZ NC_013008.1 2724627 2725451 R epimerase, with NAD(P)-binding Rossmann-fold domain complement(2724627..2725451) Escherichia coli O157:H7 str. TW14359 8217333 YP_003078636.1 CDS ECSP_2768 NC_013008.1 2725524 2725730 D hypothetical protein 2725524..2725730 Escherichia coli O157:H7 str. TW14359 8217334 YP_003078638.1 CDS hisG NC_013008.1 2726073 2726972 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2726073..2726972 Escherichia coli O157:H7 str. TW14359 8217336 YP_003078639.1 CDS hisD NC_013008.1 2726978 2728282 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2726978..2728282 Escherichia coli O157:H7 str. TW14359 8217337 YP_003078640.1 CDS hisC NC_013008.1 2728279 2729349 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2728279..2729349 Escherichia coli O157:H7 str. TW14359 8217338 YP_003078641.1 CDS hisB NC_013008.1 2729349 2730416 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2729349..2730416 Escherichia coli O157:H7 str. TW14359 8217339 YP_003078642.1 CDS hisH NC_013008.1 2730416 2731006 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2730416..2731006 Escherichia coli O157:H7 str. TW14359 8217340 YP_003078643.1 CDS hisA NC_013008.1 2731006 2731743 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2731006..2731743 Escherichia coli O157:H7 str. TW14359 8217341 YP_003078644.1 CDS hisF NC_013008.1 2731725 2732501 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2731725..2732501 Escherichia coli O157:H7 str. TW14359 8217342 YP_003078645.1 CDS hisI NC_013008.1 2732495 2733106 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 2732495..2733106 Escherichia coli O157:H7 str. TW14359 8217343 YP_003078646.1 CDS cld NC_013008.1 2733203 2734180 R regulator of length of O-antigen component of lipopolysaccharide chains complement(2733203..2734180) Escherichia coli O157:H7 str. TW14359 8217344 YP_003078647.1 CDS ugd NC_013008.1 2734326 2735492 R UDP-glucose 6-dehydrogenase complement(2734326..2735492) Escherichia coli O157:H7 str. TW14359 8217345 YP_003078648.1 CDS gnd NC_013008.1 2735741 2737147 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2735741..2737147) Escherichia coli O157:H7 str. TW14359 8217346 YP_003078649.1 CDS wbdR NC_013008.1 2737348 2738013 R acetyl transferase; O-antigen biosynthesis complement(2737348..2738013) Escherichia coli O157:H7 str. TW14359 8217347 YP_003078650.1 CDS ECSP_2784 NC_013008.1 2738707 2738817 R H repeat-associated protein complement(2738707..2738817) Escherichia coli O157:H7 str. TW14359 8217350 YP_003078651.1 CDS manB NC_013008.1 2739276 2740646 R phosphomannomutase complement(2739276..2740646) Escherichia coli O157:H7 str. TW14359 8217351 YP_003078652.1 CDS manC NC_013008.1 2740650 2742098 R mannose-1-phosphate guanylyltransferase complement(2740650..2742098) Escherichia coli O157:H7 str. TW14359 8217352 YP_003078653.1 CDS wbdQ NC_013008.1 2742080 2742589 R GDP-mannose mannosylhydrolase complement(2742080..2742589) Escherichia coli O157:H7 str. TW14359 8217353 YP_003078654.1 CDS ECSP_2788 NC_013008.1 2742592 2743557 R fucose synthetase complement(2742592..2743557) Escherichia coli O157:H7 str. TW14359 8217354 YP_003078655.1 CDS gmd1 NC_013008.1 2743560 2744678 R GDP-mannose dehydratase complement(2743560..2744678) Escherichia coli O157:H7 str. TW14359 8217355 YP_003078656.1 CDS wbdP NC_013008.1 2744698 2745912 R glycosyl transferase complement(2744698..2745912) Escherichia coli O157:H7 str. TW14359 8217356 YP_003078657.1 CDS per NC_013008.1 2745937 2747031 R perosamine synthetase complement(2745937..2747031) Escherichia coli O157:H7 str. TW14359 8217357 YP_003078658.1 CDS wzx NC_013008.1 2747034 2748425 R O antigen flippase complement(2747034..2748425) Escherichia coli O157:H7 str. TW14359 8217358 YP_003078659.1 CDS wbdO NC_013008.1 2748412 2749158 R glycosyl transferase complement(2748412..2749158) Escherichia coli O157:H7 str. TW14359 8217359 YP_003078660.1 CDS wzy NC_013008.1 2749127 2750311 R O antigen polymerase complement(2749127..2750311) Escherichia coli O157:H7 str. TW14359 8217360 YP_003078661.1 CDS wbdN NC_013008.1 2750308 2751090 R glycosyl transferase complement(2750308..2751090) Escherichia coli O157:H7 str. TW14359 8217361 YP_003078662.1 CDS galF NC_013008.1 2751409 2752302 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase complement(2751409..2752302) Escherichia coli O157:H7 str. TW14359 8217362 YP_003078663.1 CDS gne NC_013008.1 2752545 2753540 R UDP-N-acetylglucosamine 4-epimerase complement(2752545..2753540) Escherichia coli O157:H7 str. TW14359 8217363 YP_003078664.1 CDS wcaM NC_013008.1 2753698 2755092 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2753698..2755092) Escherichia coli O157:H7 str. TW14359 8217364 YP_003078665.1 CDS wcaL NC_013008.1 2755103 2756323 R glycosyl transferase complement(2755103..2756323) Escherichia coli O157:H7 str. TW14359 8217365 YP_003078666.1 CDS wcaK NC_013008.1 2756320 2757600 R pyruvyl transferase complement(2756320..2757600) Escherichia coli O157:H7 str. TW14359 8217366 YP_003078667.1 CDS wzxC NC_013008.1 2757780 2759258 R colanic acid exporter complement(2757780..2759258) Escherichia coli O157:H7 str. TW14359 8217367 YP_003078668.1 CDS wcaJ NC_013008.1 2759260 2760654 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2759260..2760654) Escherichia coli O157:H7 str. TW14359 8217368 YP_003078669.1 CDS cpsG NC_013008.1 2760709 2762079 R phosphomannomutase complement(2760709..2762079) Escherichia coli O157:H7 str. TW14359 8217369 YP_003078670.1 CDS cpsB NC_013008.1 2762272 2763708 R mannose-1-phosphate guanylyltransferase complement(2762272..2763708) Escherichia coli O157:H7 str. TW14359 8217370 YP_003078671.1 CDS wcaI NC_013008.1 2763711 2764934 R glycosyl transferase complement(2763711..2764934) Escherichia coli O157:H7 str. TW14359 8217371 YP_003078672.1 CDS gmm NC_013008.1 2764931 2765410 R GDP-mannose mannosyl hydrolase complement(2764931..2765410) Escherichia coli O157:H7 str. TW14359 8217372 YP_003078673.1 CDS ECSP_2807 NC_013008.1 2765413 2766378 R bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase complement(2765413..2766378) Escherichia coli O157:H7 str. TW14359 8217373 YP_003078674.1 CDS gmd2 NC_013008.1 2766381 2767502 R GDP-D-mannose dehydratase, NAD(P)-binding complement(2766381..2767502) Escherichia coli O157:H7 str. TW14359 8217374 YP_003078675.1 CDS wcaF NC_013008.1 2767531 2768079 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2767531..2768079) Escherichia coli O157:H7 str. TW14359 8217375 YP_003078676.1 CDS wcaE NC_013008.1 2768095 2768841 R glycosyl transferase complement(2768095..2768841) Escherichia coli O157:H7 str. TW14359 8217376 YP_003078677.1 CDS wcaD NC_013008.1 2768852 2770069 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2768852..2770069) Escherichia coli O157:H7 str. TW14359 8217377 YP_003078678.1 CDS wcaC NC_013008.1 2770044 2771261 R glycosyl transferase complement(2770044..2771261) Escherichia coli O157:H7 str. TW14359 8217378 YP_003078679.1 CDS wcaB NC_013008.1 2771258 2771746 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2771258..2771746) Escherichia coli O157:H7 str. TW14359 8217379 YP_003078680.1 CDS wcaA NC_013008.1 2771749 2772588 R glycosyl transferase complement(2771749..2772588) Escherichia coli O157:H7 str. TW14359 8217380 YP_003078681.1 CDS wzc NC_013008.1 2772681 2774843 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2772681..2774843) Escherichia coli O157:H7 str. TW14359 8217381 YP_003078682.1 CDS wzb NC_013008.1 2774846 2775289 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2774846..2775289) Escherichia coli O157:H7 str. TW14359 8217382 YP_003078683.1 CDS wza NC_013008.1 2775295 2776434 R capsular polysaccharide translocation lipoprotein complement(2775295..2776434) Escherichia coli O157:H7 str. TW14359 8217383 YP_003078684.1 CDS yegH NC_013008.1 2777093 2778676 D fused membrane protein, membrane protein 2777093..2778676 Escherichia coli O157:H7 str. TW14359 8217384 YP_003078685.1 CDS ECSP_2819 NC_013008.1 2778751 2779089 D hypothetical protein 2778751..2779089 Escherichia coli O157:H7 str. TW14359 8217385 YP_003078686.1 CDS ECSP_2820 NC_013008.1 2779079 2779369 D hypothetical protein 2779079..2779369 Escherichia coli O157:H7 str. TW14359 8217386 YP_003078687.1 CDS asmA NC_013008.1 2779422 2781275 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2779422..2781275) Escherichia coli O157:H7 str. TW14359 8217387 YP_003078688.1 CDS dcd NC_013008.1 2781297 2781878 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2781297..2781878) Escherichia coli O157:H7 str. TW14359 8217388 YP_003078689.1 CDS udk NC_013008.1 2781970 2782611 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2781970..2782611) Escherichia coli O157:H7 str. TW14359 8217389 YP_003078690.1 CDS alkA NC_013008.1 2786348 2787196 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase complement(2786348..2787196) Escherichia coli O157:H7 str. TW14359 8217391 YP_003078691.1 CDS yegD NC_013008.1 2787329 2788681 D chaperone 2787329..2788681 Escherichia coli O157:H7 str. TW14359 8217392 YP_003078692.1 CDS yegI NC_013008.1 2788694 2790634 R hypothetical protein complement(2788694..2790634) Escherichia coli O157:H7 str. TW14359 8217393 YP_003078693.1 CDS yegK NC_013008.1 2790631 2791392 R hypothetical protein complement(2790631..2791392) Escherichia coli O157:H7 str. TW14359 8217394 YP_003078694.1 CDS yegL NC_013008.1 2791389 2792048 R hypothetical protein complement(2791389..2792048) Escherichia coli O157:H7 str. TW14359 8217395 YP_003078695.1 CDS ECSP_2830 NC_013008.1 2792619 2792765 D hypothetical protein 2792619..2792765 Escherichia coli O157:H7 str. TW14359 8217396 YP_003078696.1 CDS mdtA NC_013008.1 2793264 2794511 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2793264..2794511 Escherichia coli O157:H7 str. TW14359 8217397 YP_003078697.1 CDS mdtB NC_013008.1 2794511 2797633 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2794511..2797633 Escherichia coli O157:H7 str. TW14359 8217398 YP_003078698.1 CDS mdtC NC_013008.1 2797634 2800711 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2797634..2800711 Escherichia coli O157:H7 str. TW14359 8217399 YP_003078699.1 CDS mdtD NC_013008.1 2800712 2802127 D multidrug efflux system protein MdtE 2800712..2802127 Escherichia coli O157:H7 str. TW14359 8217400 YP_003078700.1 CDS baeS NC_013008.1 2802124 2803527 D signal transduction histidine-protein kinase BaeS 2802124..2803527 Escherichia coli O157:H7 str. TW14359 8217401 YP_003078701.1 CDS baeR NC_013008.1 2803524 2804246 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2803524..2804246 Escherichia coli O157:H7 str. TW14359 8217402 YP_003078702.1 CDS yegP NC_013008.1 2804437 2804769 D hypothetical protein 2804437..2804769 Escherichia coli O157:H7 str. TW14359 8217403 YP_003078703.1 CDS yegQ NC_013008.1 2804917 2806278 D peptidase 2804917..2806278 Escherichia coli O157:H7 str. TW14359 8217404 YP_003078704.1 CDS ECSP_2839 NC_013008.1 2806552 2806806 R in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator complement(2806552..2806806) Escherichia coli O157:H7 str. TW14359 8217405 YP_003078705.1 CDS ECSP_2840 NC_013008.1 2806852 2808015 R phage protein D complement(2806852..2808015) Escherichia coli O157:H7 str. TW14359 8217406 YP_003078706.1 CDS ECSP_2841 NC_013008.1 2808015 2808494 R phage protein gpU complement(2808015..2808494) Escherichia coli O157:H7 str. TW14359 8217407 YP_003078707.1 CDS ECSP_2842 NC_013008.1 2808509 2810956 R phage related tail protein complement(2808509..2810956) Escherichia coli O157:H7 str. TW14359 8217408 YP_003078708.1 CDS ECSP_2843 NC_013008.1 2811101 2811376 R hypothetical protein complement(2811101..2811376) Escherichia coli O157:H7 str. TW14359 8217409 YP_003078709.1 CDS ECSP_2844 NC_013008.1 2811433 2811951 R phage tail tube protein FII complement(2811433..2811951) Escherichia coli O157:H7 str. TW14359 8217410 YP_003078710.1 CDS ECSP_2845 NC_013008.1 2811964 2813154 R phage tail sheath protein FI complement(2811964..2813154) Escherichia coli O157:H7 str. TW14359 8217411 YP_003078711.1 CDS ECSP_2846 NC_013008.1 2813214 2813807 R DNA-invertase complement(2813214..2813807) Escherichia coli O157:H7 str. TW14359 8217412 YP_003078712.1 CDS ECSP_2847 NC_013008.1 2813838 2814248 D tail fiber protein 2813838..2814248 Escherichia coli O157:H7 str. TW14359 8217413 YP_003078713.1 CDS ECSP_2848 NC_013008.1 2814269 2814712 D tail fiber assembly protein 2814269..2814712 Escherichia coli O157:H7 str. TW14359 8217414 YP_003078714.1 CDS ECSP_2849 NC_013008.1 2814684 2815286 R tail fiber assembly protein complement(2814684..2815286) Escherichia coli O157:H7 str. TW14359 8217415 YP_003078715.1 CDS ECSP_2850 NC_013008.1 2815286 2816605 R phage tail fiber protein complement(2815286..2816605) Escherichia coli O157:H7 str. TW14359 8217416 YP_003078716.1 CDS ECSP_2851 NC_013008.1 2816602 2817213 R phage P2-related tail formation protein complement(2816602..2817213) Escherichia coli O157:H7 str. TW14359 8217417 YP_003078717.1 CDS ECSP_2852 NC_013008.1 2817206 2818114 R baseplate assembly protein complement(2817206..2818114) Escherichia coli O157:H7 str. TW14359 8217418 YP_003078718.1 CDS ECSP_2853 NC_013008.1 2818119 2818466 R phage baseplate protein complement(2818119..2818466) Escherichia coli O157:H7 str. TW14359 8217419 YP_003078719.1 CDS ECSP_2854 NC_013008.1 2818463 2819098 R phage baseplate protein complement(2818463..2819098) Escherichia coli O157:H7 str. TW14359 8217420 YP_003078720.1 CDS ECSP_2855 NC_013008.1 2819165 2819617 R phage tail protein complement(2819165..2819617) Escherichia coli O157:H7 str. TW14359 8217421 YP_003078721.1 CDS ECSP_2856 NC_013008.1 2819610 2820077 R P2 phage tail completion protein R, GpR complement(2819610..2820077) Escherichia coli O157:H7 str. TW14359 8217422 YP_003078722.1 CDS ECSP_2857 NC_013008.1 2820040 2820198 R phage lysis protein LysC complement(2820040..2820198) Escherichia coli O157:H7 str. TW14359 8217423 YP_003078723.1 CDS ECSP_2858 NC_013008.1 2820185 2820610 R phage lysis timing protein LysB complement(2820185..2820610) Escherichia coli O157:H7 str. TW14359 8217424 YP_003078724.1 CDS ECSP_2859 NC_013008.1 2820598 2821023 R phage lysis protein LysA complement(2820598..2821023) Escherichia coli O157:H7 str. TW14359 8217425 YP_003078725.1 CDS ECSP_2860 NC_013008.1 2821038 2821535 R phage lysozyme complement(2821038..2821535) Escherichia coli O157:H7 str. TW14359 8217426 YP_003078726.1 CDS ECSP_2861 NC_013008.1 2821535 2821816 R hypothetical protein complement(2821535..2821816) Escherichia coli O157:H7 str. TW14359 8217427 YP_003078727.1 CDS ECSP_2862 NC_013008.1 2821820 2822023 R P2-like prophage tail protein X complement(2821820..2822023) Escherichia coli O157:H7 str. TW14359 8217428 YP_003078728.1 CDS ECSP_2863 NC_013008.1 2822023 2822496 R capsid completion protein complement(2822023..2822496) Escherichia coli O157:H7 str. TW14359 8217429 YP_003078729.1 CDS ECSP_2864 NC_013008.1 2822632 2823375 R small terminase subunit complement(2822632..2823375) Escherichia coli O157:H7 str. TW14359 8217430 YP_003078730.1 CDS ECSP_2865 NC_013008.1 2823379 2824452 R phage major capsid protein, P2 family complement(2823379..2824452) Escherichia coli O157:H7 str. TW14359 8217431 YP_003078731.1 CDS ECSP_2866 NC_013008.1 2824511 2825365 R phage capsid scaffolding protein GpO complement(2824511..2825365) Escherichia coli O157:H7 str. TW14359 8217432 YP_003078732.1 CDS ECSP_2867 NC_013008.1 2825539 2827311 D phage large terminase subunit GpP 2825539..2827311 Escherichia coli O157:H7 str. TW14359 8217433 YP_003078733.1 CDS ECSP_2868 NC_013008.1 2827311 2828345 D phage capsid protein 2827311..2828345 Escherichia coli O157:H7 str. TW14359 8217434 YP_003078734.1 CDS ECSP_2869 NC_013008.1 2828384 2828545 R hypothetical protein complement(2828384..2828545) Escherichia coli O157:H7 str. TW14359 8217435 YP_003078735.1 CDS ECSP_2870 NC_013008.1 2828663 2830630 R virulence factor complement(2828663..2830630) Escherichia coli O157:H7 str. TW14359 8217436 YP_003078736.1 CDS ECSP_2871 NC_013008.1 2830630 2831142 R hypothetical protein complement(2830630..2831142) Escherichia coli O157:H7 str. TW14359 8217437 YP_003078737.1 CDS ECSP_2872 NC_013008.1 2831129 2832352 R virulence factor complement(2831129..2832352) Escherichia coli O157:H7 str. TW14359 8217438 YP_003078738.1 CDS ECSP_2873 NC_013008.1 2832442 2834724 R phage replication initiation protein complement(2832442..2834724) Escherichia coli O157:H7 str. TW14359 8217439 YP_003078739.1 CDS ECSP_2874 NC_013008.1 2834714 2834989 R hypothetical protein complement(2834714..2834989) Escherichia coli O157:H7 str. TW14359 8217440 YP_003078740.1 CDS ECSP_2875 NC_013008.1 2834986 2835210 R hypothetical protein complement(2834986..2835210) Escherichia coli O157:H7 str. TW14359 8217441 YP_003078741.1 CDS ECSP_2876 NC_013008.1 2835213 2835512 R hypothetical protein complement(2835213..2835512) Escherichia coli O157:H7 str. TW14359 8217442 YP_003078742.1 CDS ECSP_2877 NC_013008.1 2835512 2835736 R hypothetical protein complement(2835512..2835736) Escherichia coli O157:H7 str. TW14359 8217443 YP_003078743.1 CDS ECSP_2878 NC_013008.1 2835800 2836300 R replication gene B protein complement(2835800..2836300) Escherichia coli O157:H7 str. TW14359 8217444 YP_003078744.1 CDS ECSP_2879 NC_013008.1 2836297 2836467 R hypothetical protein complement(2836297..2836467) Escherichia coli O157:H7 str. TW14359 8217445 YP_003078745.1 CDS ECSP_2880 NC_013008.1 2836478 2836663 R hypothetical protein complement(2836478..2836663) Escherichia coli O157:H7 str. TW14359 8217446 YP_003078746.1 CDS ECSP_2881 NC_013008.1 2836803 2837174 D immunity repressor 2836803..2837174 Escherichia coli O157:H7 str. TW14359 8217447 YP_003078747.1 CDS ECSP_2882 NC_013008.1 2837290 2838303 D integrase 2837290..2838303 Escherichia coli O157:H7 str. TW14359 8217448 YP_003078748.1 CDS yegR NC_013008.1 2838568 2838885 R hypothetical protein complement(2838568..2838885) Escherichia coli O157:H7 str. TW14359 8217449 YP_003078749.1 CDS yegS NC_013008.1 2839291 2840190 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2839291..2840190 Escherichia coli O157:H7 str. TW14359 8217450 YP_003078750.1 CDS gatR NC_013008.1 2840272 2841051 R galactitol utilization operon repressor complement(2840272..2841051) Escherichia coli O157:H7 str. TW14359 8217451 YP_003078751.1 CDS gatD NC_013008.1 2841151 2842191 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2841151..2842191) Escherichia coli O157:H7 str. TW14359 8217452 YP_003078752.1 CDS gatC NC_013008.1 2842239 2843594 R galactitol-specific enzyme IIC component of PTS complement(2842239..2843594) Escherichia coli O157:H7 str. TW14359 8217453 YP_003078753.1 CDS gatB NC_013008.1 2843598 2843882 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2843598..2843882) Escherichia coli O157:H7 str. TW14359 8217454 YP_003078754.1 CDS gatA NC_013008.1 2843913 2844365 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2843913..2844365) Escherichia coli O157:H7 str. TW14359 8217455 YP_003078755.1 CDS gatZ NC_013008.1 2844375 2845637 R D-tagatose 1,6-bisphosphate aldolase 2 subunit complement(2844375..2845637) Escherichia coli O157:H7 str. TW14359 8217456 YP_003078756.1 CDS gatY NC_013008.1 2845666 2846520 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2845666..2846520) Escherichia coli O157:H7 str. TW14359 8217457 YP_003078757.1 CDS fbaB NC_013008.1 2846819 2847871 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2846819..2847871) Escherichia coli O157:H7 str. TW14359 8217458 YP_003078758.1 CDS yegT NC_013008.1 2848128 2849405 D nucleoside transporter 2848128..2849405 Escherichia coli O157:H7 str. TW14359 8217459 YP_003078759.1 CDS yegU NC_013008.1 2849402 2850406 D hydrolase 2849402..2850406 Escherichia coli O157:H7 str. TW14359 8217460 YP_003078760.1 CDS yegV NC_013008.1 2850403 2851368 D kinase 2850403..2851368 Escherichia coli O157:H7 str. TW14359 8217461 YP_003078761.1 CDS yegW NC_013008.1 2851342 2852088 R DNA-binding transcriptional regulator complement(2851342..2852088) Escherichia coli O157:H7 str. TW14359 8217462 YP_003078762.1 CDS yegX NC_013008.1 2852140 2852958 R hydrolase complement(2852140..2852958) Escherichia coli O157:H7 str. TW14359 8217463 YP_003078763.1 CDS thiD NC_013008.1 2853023 2853823 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2853023..2853823) Escherichia coli O157:H7 str. TW14359 8217464 YP_003078764.1 CDS thiM NC_013008.1 2853820 2854608 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2853820..2854608) Escherichia coli O157:H7 str. TW14359 8217465 YP_003078765.1 CDS ECSP_2900 NC_013008.1 2854942 2855181 D hypothetical protein 2854942..2855181 Escherichia coli O157:H7 str. TW14359 8217466 YP_003078766.1 CDS ECSP_2901 NC_013008.1 2855745 2855864 R hypothetical protein complement(2855745..2855864) Escherichia coli O157:H7 str. TW14359 8217467 YP_003078767.1 CDS ECSP_2902 NC_013008.1 2856232 2856579 D hypothetical protein 2856232..2856579 Escherichia coli O157:H7 str. TW14359 8217468 YP_003078768.1 CDS ECSP_2903 NC_013008.1 2856589 2856903 D hypothetical protein 2856589..2856903 Escherichia coli O157:H7 str. TW14359 8217469 YP_003078769.1 CDS rcnR NC_013008.1 2857013 2857285 R transcriptional repressor of rcnA complement(2857013..2857285) Escherichia coli O157:H7 str. TW14359 8217470 YP_003078770.1 CDS yohM NC_013008.1 2857406 2858263 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2857406..2858263 Escherichia coli O157:H7 str. TW14359 8217471 YP_003078771.1 CDS yohN NC_013008.1 2858481 2858819 D hypothetical protein 2858481..2858819 Escherichia coli O157:H7 str. TW14359 8217472 YP_003078772.1 CDS ECSP_2907 NC_013008.1 2858901 2859935 R fimbrial protein complement(2858901..2859935) Escherichia coli O157:H7 str. TW14359 8217473 YP_003078773.1 CDS yehB NC_013008.1 2859946 2862426 R outer membrane protein complement(2859946..2862426) Escherichia coli O157:H7 str. TW14359 8217474 YP_003078774.1 CDS yehC NC_013008.1 2862442 2863164 R periplasmic pilin chaperone complement(2862442..2863164) Escherichia coli O157:H7 str. TW14359 8217475 YP_003078775.1 CDS yehD NC_013008.1 2863204 2863746 R fimbrial-like adhesin protein complement(2863204..2863746) Escherichia coli O157:H7 str. TW14359 8217476 YP_003078776.1 CDS yehE NC_013008.1 2864038 2864319 R hypothetical protein complement(2864038..2864319) Escherichia coli O157:H7 str. TW14359 8217477 YP_003078777.1 CDS mrp NC_013008.1 2864581 2865690 R ATPase complement(2864581..2865690) Escherichia coli O157:H7 str. TW14359 8217478 YP_003078778.1 CDS metG NC_013008.1 2865822 2867855 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2865822..2867855 Escherichia coli O157:H7 str. TW14359 8217479 YP_003078779.1 CDS ECSP_2914 NC_013008.1 2867996 2868724 D regulator 2867996..2868724 Escherichia coli O157:H7 str. TW14359 8217480 YP_003078780.1 CDS ECSP_2915 NC_013008.1 2869508 2869834 D transposase 2869508..2869834 Escherichia coli O157:H7 str. TW14359 8217481 YP_003078781.1 CDS ECSP_2916 NC_013008.1 2869831 2870721 D transposase 2869831..2870721 Escherichia coli O157:H7 str. TW14359 8217482 YP_003078782.1 CDS yehI NC_013008.1 2876126 2879755 D hypothetical protein 2876126..2879755 Escherichia coli O157:H7 str. TW14359 8217485 YP_003078783.1 CDS yehK NC_013008.1 2879817 2880134 D hypothetical protein 2879817..2880134 Escherichia coli O157:H7 str. TW14359 8217486 YP_003078785.1 CDS ECSP_2922 NC_013008.1 2880559 2880711 R hypothetical protein complement(2880559..2880711) Escherichia coli O157:H7 str. TW14359 8217488 YP_003078787.1 CDS yehL NC_013008.1 2881375 2882463 D ABC transporter ATP-binding protein 2881375..2882463 Escherichia coli O157:H7 str. TW14359 8217490 YP_003078788.1 CDS yehP NC_013008.1 2884746 2885882 D hypothetical protein 2884746..2885882 Escherichia coli O157:H7 str. TW14359 8217492 YP_003078789.1 CDS yehQ NC_013008.1 2885879 2887882 D hypothetical protein 2885879..2887882 Escherichia coli O157:H7 str. TW14359 8217493 YP_003078790.1 CDS yehR NC_013008.1 2888007 2888468 D hypothetical protein 2888007..2888468 Escherichia coli O157:H7 str. TW14359 8217494 YP_003078791.1 CDS yehS NC_013008.1 2888510 2888980 R hypothetical protein complement(2888510..2888980) Escherichia coli O157:H7 str. TW14359 8217495 YP_003078792.1 CDS yehT NC_013008.1 2889027 2889746 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2889027..2889746) Escherichia coli O157:H7 str. TW14359 8217496 YP_003078793.1 CDS yehU NC_013008.1 2889743 2891428 R sensory kinase in two-component system with YehT complement(2889743..2891428) Escherichia coli O157:H7 str. TW14359 8217497 YP_003078794.1 CDS ECSP_2932 NC_013008.1 2891943 2892191 D hypothetical protein 2891943..2892191 Escherichia coli O157:H7 str. TW14359 8217498 YP_003078795.1 CDS ECSP_2933 NC_013008.1 2892559 2892828 R hypothetical protein complement(2892559..2892828) Escherichia coli O157:H7 str. TW14359 8217499 YP_003078796.1 CDS ECSP_2934 NC_013008.1 2892830 2894143 R tail fiber protein complement(2892830..2894143) Escherichia coli O157:H7 str. TW14359 8217500 YP_003078797.1 CDS ECSP_2935 NC_013008.1 2894208 2894807 R outer membrane protein Lom complement(2894208..2894807) Escherichia coli O157:H7 str. TW14359 8217501 YP_003078798.1 CDS ECSP_2936 NC_013008.1 2894875 2898348 R host specificity protein J complement(2894875..2898348) Escherichia coli O157:H7 str. TW14359 8217502 YP_003078799.1 CDS ECSP_2937 NC_013008.1 2898589 2899167 R tail assembly protein complement(2898589..2899167) Escherichia coli O157:H7 str. TW14359 8217503 YP_003078800.1 CDS ECSP_2938 NC_013008.1 2899164 2900045 R tail fiber component K of prophage CP-933U complement(2899164..2900045) Escherichia coli O157:H7 str. TW14359 8217504 YP_003078801.1 CDS ECSP_2939 NC_013008.1 2899918 2900616 R tail fiber component L of prophage CP-933U complement(2899918..2900616) Escherichia coli O157:H7 str. TW14359 8217505 YP_003078802.1 CDS ECSP_2940 NC_013008.1 2900616 2900945 R tail fiber component M of prophage CP-933U complement(2900616..2900945) Escherichia coli O157:H7 str. TW14359 8217506 YP_003078803.1 CDS ECSP_2941 NC_013008.1 2900942 2903587 R tail length tape measure protein complement(2900942..2903587) Escherichia coli O157:H7 str. TW14359 8217507 YP_003078804.1 CDS ECSP_2942 NC_013008.1 2903631 2903939 R phage tail assembly protein T complement(2903631..2903939) Escherichia coli O157:H7 str. TW14359 8217508 YP_003078805.1 CDS ECSP_2943 NC_013008.1 2903966 2904388 R tail fiber component G of prophage CP-933U complement(2903966..2904388) Escherichia coli O157:H7 str. TW14359 8217509 YP_003078806.1 CDS ECSP_2944 NC_013008.1 2904402 2905154 R tail fiber component V of prophage CP-933U complement(2904402..2905154) Escherichia coli O157:H7 str. TW14359 8217510 YP_003078807.1 CDS ECSP_2945 NC_013008.1 2905162 2905560 R tail fiber component U of prophage CP-933U complement(2905162..2905560) Escherichia coli O157:H7 str. TW14359 8217511 YP_003078808.1 CDS ECSP_2946 NC_013008.1 2905573 2906202 R tail fiber component Z of prophage CP-933U complement(2905573..2906202) Escherichia coli O157:H7 str. TW14359 8217512 YP_003078809.1 CDS ECSP_2947 NC_013008.1 2906199 2906480 R hypothetical protein complement(2906199..2906480) Escherichia coli O157:H7 str. TW14359 8217513 YP_003078810.1 CDS ECSP_2948 NC_013008.1 2906473 2906799 R hypothetical protein complement(2906473..2906799) Escherichia coli O157:H7 str. TW14359 8217514 YP_003078811.1 CDS ECSP_2949 NC_013008.1 2906887 2907927 R hypothetical protein complement(2906887..2907927) Escherichia coli O157:H7 str. TW14359 8217515 YP_003078812.1 CDS ECSP_2950 NC_013008.1 2908856 2910358 R head-tail preconnector protein of prophage CP-933U complement(2908856..2910358) Escherichia coli O157:H7 str. TW14359 8217516 YP_003078813.1 CDS ECSP_2951 NC_013008.1 2910567 2912579 R DNA packaging protein of prophage CP-933U complement(2910567..2912579) Escherichia coli O157:H7 str. TW14359 8217517 YP_003078814.1 CDS ECSP_2952 NC_013008.1 2912687 2913163 R hypothetical protein complement(2912687..2913163) Escherichia coli O157:H7 str. TW14359 8217518 YP_003078815.1 CDS ECSP_2953 NC_013008.1 2913618 2914085 R endopeptidase of prophage CP-933U complement(2913618..2914085) Escherichia coli O157:H7 str. TW14359 8217519 YP_003078816.1 CDS antV NC_013008.1 2914239 2914808 R antirepressor of prophage CP-933V complement(2914239..2914808) Escherichia coli O157:H7 str. TW14359 8217520 YP_003078817.1 CDS ECSP_2955 NC_013008.1 2915079 2915612 R endolysin R of prophage CP-933V complement(2915079..2915612) Escherichia coli O157:H7 str. TW14359 8217521 YP_003078818.1 CDS ECSP_2956 NC_013008.1 2915617 2915889 R lysis protein S of prophage CP-933V complement(2915617..2915889) Escherichia coli O157:H7 str. TW14359 8217522 YP_003078819.1 CDS ECSP_2957 NC_013008.1 2915910 2916329 R hypothetical protein complement(2915910..2916329) Escherichia coli O157:H7 str. TW14359 8217523 YP_003078820.1 CDS ECSP_2958 NC_013008.1 2916512 2918458 R hypothetical protein complement(2916512..2918458) Escherichia coli O157:H7 str. TW14359 8217524 YP_003078821.1 CDS ECSP_2959 NC_013008.1 2918698 2918844 D hypothetical protein 2918698..2918844 Escherichia coli O157:H7 str. TW14359 8217525 YP_003078822.1 CDS ECSP_2963 NC_013008.1 2919262 2919414 R hypothetical protein complement(2919262..2919414) Escherichia coli O157:H7 str. TW14359 8217529 YP_003078823.1 CDS ECSP_2964 NC_013008.1 2919666 2920100 R antitermination protein Q of bacteriophage complement(2919666..2920100) Escherichia coli O157:H7 str. TW14359 8217530 YP_003078824.1 CDS ECSP_2965 NC_013008.1 2920186 2920323 R hypothetical protein complement(2920186..2920323) Escherichia coli O157:H7 str. TW14359 8217531 YP_003078825.1 CDS ECSP_2966 NC_013008.1 2920323 2920685 R DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS complement(2920323..2920685) Escherichia coli O157:H7 str. TW14359 8217532 YP_003078826.1 CDS ECSP_2967 NC_013008.1 2920682 2920972 R hypothetical protein complement(2920682..2920972) Escherichia coli O157:H7 str. TW14359 8217533 YP_003078827.1 CDS ECSP_2968 NC_013008.1 2921135 2921590 R DLP12 prophage; hypothetical protein complement(2921135..2921590) Escherichia coli O157:H7 str. TW14359 8217534 YP_003078828.1 CDS ECSP_2969 NC_013008.1 2921805 2922602 R DNA-binding transcriptional regulator complement(2921805..2922602) Escherichia coli O157:H7 str. TW14359 8217535 YP_003078829.1 CDS ECSP_2970 NC_013008.1 2922612 2923163 R DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor complement(2922612..2923163) Escherichia coli O157:H7 str. TW14359 8217536 YP_003078830.1 CDS ECSP_2971 NC_013008.1 2923628 2925154 R DLP12 prophage recombinase complement(2923628..2925154) Escherichia coli O157:H7 str. TW14359 8217537 YP_003078831.1 CDS emrE NC_013008.1 2925411 2925743 R member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein complement(2925411..2925743) Escherichia coli O157:H7 str. TW14359 8217538 YP_003078832.1 CDS ECSP_2973 NC_013008.1 2925811 2926113 R Ren protein complement(2925811..2926113) Escherichia coli O157:H7 str. TW14359 8217539 YP_003078833.1 CDS ECSP_2974 NC_013008.1 2926110 2926547 R replication protein P complement(2926110..2926547) Escherichia coli O157:H7 str. TW14359 8217540 YP_003078834.1 CDS ECSP_2975 NC_013008.1 2926602 2926928 D transposase 2926602..2926928 Escherichia coli O157:H7 str. TW14359 8217541 YP_003078835.1 CDS ECSP_2976 NC_013008.1 2926925 2927815 D transposase 2926925..2927815 Escherichia coli O157:H7 str. TW14359 8217542 YP_003078836.1 CDS ECSP_2977 NC_013008.1 2927855 2928124 R replication protein P of bacteriophage complement(2927855..2928124) Escherichia coli O157:H7 str. TW14359 8217543 YP_003078837.1 CDS ECSP_2978 NC_013008.1 2928121 2929140 R replication protein O complement(2928121..2929140) Escherichia coli O157:H7 str. TW14359 8217544 YP_003078838.1 CDS ECSP_2979 NC_013008.1 2929137 2929676 R bacteriophage regulatory protein complement(2929137..2929676) Escherichia coli O157:H7 str. TW14359 8217545 YP_003078839.1 CDS ECSP_2980 NC_013008.1 2929746 2929976 R hypothetical protein complement(2929746..2929976) Escherichia coli O157:H7 str. TW14359 8217546 YP_003078840.1 CDS ECSP_2981 NC_013008.1 2930156 2930770 D phage-related repressor protein 2930156..2930770 Escherichia coli O157:H7 str. TW14359 8217547 YP_003078841.1 CDS ECSP_2982 NC_013008.1 2930851 2931912 D hypothetical protein 2930851..2931912 Escherichia coli O157:H7 str. TW14359 8217548 YP_003078842.1 CDS ECSP_2983 NC_013008.1 2931890 2932267 D hypothetical protein 2931890..2932267 Escherichia coli O157:H7 str. TW14359 8217549 YP_003078843.1 CDS kil2 NC_013008.1 2932664 2932954 D prophage Kil protein 2932664..2932954 Escherichia coli O157:H7 str. TW14359 8217550 YP_003078844.1 CDS ECSP_2985 NC_013008.1 2933030 2933326 D protein gam 2933030..2933326 Escherichia coli O157:H7 str. TW14359 8217551 YP_003078845.1 CDS bet2 NC_013008.1 2933332 2934117 D protein bet 2933332..2934117 Escherichia coli O157:H7 str. TW14359 8217552 YP_003078846.1 CDS ECSP_2987 NC_013008.1 2934114 2934791 D exonuclease of prophage CP-933V 2934114..2934791 Escherichia coli O157:H7 str. TW14359 8217553 YP_003078847.1 CDS ECSP_2988 NC_013008.1 2934946 2935137 D hypothetical protein 2934946..2935137 Escherichia coli O157:H7 str. TW14359 8217554 YP_003078848.1 CDS ECSP_2989 NC_013008.1 2935148 2935429 D hypothetical protein 2935148..2935429 Escherichia coli O157:H7 str. TW14359 8217555 YP_003078849.1 CDS ECSP_2990 NC_013008.1 2935528 2935749 D DnaK suppressor protein 2935528..2935749 Escherichia coli O157:H7 str. TW14359 8217556 YP_003078850.1 CDS ECSP_2991 NC_013008.1 2935746 2936693 D hypothetical protein 2935746..2936693 Escherichia coli O157:H7 str. TW14359 8217557 YP_003078851.1 CDS ECSP_2992 NC_013008.1 2936841 2937128 D hypothetical protein 2936841..2937128 Escherichia coli O157:H7 str. TW14359 8217558 YP_003078852.1 CDS ECSP_2994 NC_013008.1 2938008 2938250 D hypothetical protein 2938008..2938250 Escherichia coli O157:H7 str. TW14359 8217560 YP_003078853.1 CDS ECSP_2995 NC_013008.1 2938254 2938388 D hypothetical protein 2938254..2938388 Escherichia coli O157:H7 str. TW14359 8217561 YP_003078854.1 CDS ECSP_2996 NC_013008.1 2938407 2938661 D excisionase 2938407..2938661 Escherichia coli O157:H7 str. TW14359 8217562 YP_003078855.1 CDS intV NC_013008.1 2938695 2939981 D integrase for prophage CP-933V 2938695..2939981 Escherichia coli O157:H7 str. TW14359 8217563 YP_003078856.1 CDS mlrA NC_013008.1 2940056 2940703 D DNA-binding transcriptional regulator 2940056..2940703 Escherichia coli O157:H7 str. TW14359 8217564 YP_003078857.1 CDS yohO NC_013008.1 2940763 2940870 D hypothetical protein 2940763..2940870 Escherichia coli O157:H7 str. TW14359 8217565 YP_003078858.1 CDS yehW NC_013008.1 2940851 2941582 R ABC transporter membrane protein complement(2940851..2941582) Escherichia coli O157:H7 str. TW14359 8217566 YP_003078859.1 CDS yehX NC_013008.1 2941587 2942513 R ABC transporter ATP-binding protein complement(2941587..2942513) Escherichia coli O157:H7 str. TW14359 8217567 YP_003078860.1 CDS yehY NC_013008.1 2942506 2943663 R ABC transporter membrane protein complement(2942506..2943663) Escherichia coli O157:H7 str. TW14359 8217568 YP_003078861.1 CDS yehZ NC_013008.1 2943670 2944587 R ABC transporter periplasmic-binding protein complement(2943670..2944587) Escherichia coli O157:H7 str. TW14359 8217569 YP_003078862.1 CDS bglX NC_013008.1 2944839 2947136 R beta-D-glucoside glucohydrolase complement(2944839..2947136) Escherichia coli O157:H7 str. TW14359 8217570 YP_003078863.1 CDS dld NC_013008.1 2947332 2949047 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2947332..2949047 Escherichia coli O157:H7 str. TW14359 8217571 YP_003078864.1 CDS pbpG NC_013008.1 2949085 2950017 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2949085..2950017) Escherichia coli O157:H7 str. TW14359 8217572 YP_003078865.1 CDS yohC NC_013008.1 2950191 2950778 R inner membrane protein complement(2950191..2950778) Escherichia coli O157:H7 str. TW14359 8217573 YP_003078866.1 CDS yohD NC_013008.1 2950948 2951526 D hypothetical protein 2950948..2951526 Escherichia coli O157:H7 str. TW14359 8217574 YP_003078867.1 CDS yohF NC_013008.1 2951656 2952417 R acetoin dehydrogenase complement(2951656..2952417) Escherichia coli O157:H7 str. TW14359 8217575 YP_003078868.1 CDS yohG NC_013008.1 2952470 2953906 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2952470..2953906) Escherichia coli O157:H7 str. TW14359 8217576 YP_003078869.1 CDS ECSP_3011 NC_013008.1 2954250 2954573 R hypothetical protein complement(2954250..2954573) Escherichia coli O157:H7 str. TW14359 8217577 YP_003078870.1 CDS dusC NC_013008.1 2954601 2955551 R tRNA-dihydrouridine synthase C complement(2954601..2955551) Escherichia coli O157:H7 str. TW14359 8217578 YP_003078871.1 CDS ECSP_3013 NC_013008.1 2955710 2956903 R catalyzes the formation of catechol from salicylate; salicylate hydroxylase complement(2955710..2956903) Escherichia coli O157:H7 str. TW14359 8217579 YP_003078872.1 CDS ECSP_3014 NC_013008.1 2956918 2957565 R glutathione-S-transferase complement(2956918..2957565) Escherichia coli O157:H7 str. TW14359 8217580 YP_003078873.1 CDS ECSP_3015 NC_013008.1 2957571 2958272 R isomerase-decarboxylase complement(2957571..2958272) Escherichia coli O157:H7 str. TW14359 8217581 YP_003078874.1 CDS ECSP_3016 NC_013008.1 2958287 2959315 R gentisate 1,2-dioxygenase complement(2958287..2959315) Escherichia coli O157:H7 str. TW14359 8217582 YP_003078875.1 CDS ECSP_3017 NC_013008.1 2959327 2960685 R transporter complement(2959327..2960685) Escherichia coli O157:H7 str. TW14359 8217583 YP_003078876.1 CDS ECSP_3018 NC_013008.1 2960764 2961720 D regulator 2960764..2961720 Escherichia coli O157:H7 str. TW14359 8217584 YP_003078877.1 CDS yohJ NC_013008.1 2961851 2962249 D hypothetical protein 2961851..2962249 Escherichia coli O157:H7 str. TW14359 8217585 YP_003078878.1 CDS yohK NC_013008.1 2962246 2962941 D hypothetical protein 2962246..2962941 Escherichia coli O157:H7 str. TW14359 8217586 YP_003078879.1 CDS cdd NC_013008.1 2963071 2963955 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2963071..2963955 Escherichia coli O157:H7 str. TW14359 8217587 YP_003078880.1 CDS sanA NC_013008.1 2964105 2964824 D hypothetical protein 2964105..2964824 Escherichia coli O157:H7 str. TW14359 8217588 YP_003078881.1 CDS yeiS NC_013008.1 2964827 2965066 D inner membrane protein 2964827..2965066 Escherichia coli O157:H7 str. TW14359 8217589 YP_003078882.1 CDS yeiT NC_013008.1 2965260 2966498 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2965260..2966498 Escherichia coli O157:H7 str. TW14359 8217590 YP_003078883.1 CDS yeiA NC_013008.1 2966492 2967727 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2966492..2967727 Escherichia coli O157:H7 str. TW14359 8217591 YP_003078884.1 CDS mglC NC_013008.1 2967970 2968980 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component complement(2967970..2968980) Escherichia coli O157:H7 str. TW14359 8217592 YP_003078885.1 CDS mglA NC_013008.1 2968996 2970516 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2968996..2970516) Escherichia coli O157:H7 str. TW14359 8217593 YP_003078886.1 CDS mglB NC_013008.1 2970577 2971575 R methyl-galactoside ABC transporter periplasmic-binding protein complement(2970577..2971575) Escherichia coli O157:H7 str. TW14359 8217594 YP_003078887.1 CDS galS NC_013008.1 2971854 2972894 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2971854..2972894) Escherichia coli O157:H7 str. TW14359 8217595 YP_003078888.1 CDS yeiB NC_013008.1 2973036 2974193 R hypothetical protein complement(2973036..2974193) Escherichia coli O157:H7 str. TW14359 8217596 YP_003078889.1 CDS folE NC_013008.1 2974210 2974878 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2974210..2974878) Escherichia coli O157:H7 str. TW14359 8217597 YP_003078890.1 CDS yeiG NC_013008.1 2975136 2975972 D esterase 2975136..2975972 Escherichia coli O157:H7 str. TW14359 8217598 YP_003078891.1 CDS cirA NC_013008.1 2976004 2977983 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2976004..2977983) Escherichia coli O157:H7 str. TW14359 8217599 YP_003078892.1 CDS lysP NC_013008.1 2978275 2979744 R lysine transporter complement(2978275..2979744) Escherichia coli O157:H7 str. TW14359 8217600 YP_003078893.1 CDS yeiE NC_013008.1 2979949 2980830 R DNA-binding transcriptional regulator complement(2979949..2980830) Escherichia coli O157:H7 str. TW14359 8217601 YP_003078894.1 CDS yeiH NC_013008.1 2980929 2981978 D hypothetical protein 2980929..2981978 Escherichia coli O157:H7 str. TW14359 8217602 YP_003078895.1 CDS nfo NC_013008.1 2982052 2982909 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2982052..2982909 Escherichia coli O157:H7 str. TW14359 8217603 YP_003078896.1 CDS yeiI NC_013008.1 2982912 2984000 D hypothetical protein 2982912..2984000 Escherichia coli O157:H7 str. TW14359 8217604 YP_003078897.1 CDS yeiJ NC_013008.1 2984056 2985306 R transport system permease complement(2984056..2985306) Escherichia coli O157:H7 str. TW14359 8217605 YP_003078898.1 CDS rihB NC_013008.1 2985406 2986347 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2985406..2986347) Escherichia coli O157:H7 str. TW14359 8217606 YP_003078899.1 CDS yeiL NC_013008.1 2986516 2987175 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2986516..2987175 Escherichia coli O157:H7 str. TW14359 8217607 YP_003078900.1 CDS yeiM NC_013008.1 2987246 2988496 R nucleoside transporter complement(2987246..2988496) Escherichia coli O157:H7 str. TW14359 8217608 YP_003078901.1 CDS yeiN NC_013008.1 2988590 2989528 R hypothetical protein complement(2988590..2989528) Escherichia coli O157:H7 str. TW14359 8217609 YP_003078902.1 CDS yeiC NC_013008.1 2989516 2990457 R hypothetical protein complement(2989516..2990457) Escherichia coli O157:H7 str. TW14359 8217610 YP_003078903.1 CDS fruA NC_013008.1 2990881 2992572 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC complement(2990881..2992572) Escherichia coli O157:H7 str. TW14359 8217611 YP_003078904.1 CDS fruK NC_013008.1 2992589 2993527 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2992589..2993527) Escherichia coli O157:H7 str. TW14359 8217612 YP_003078905.1 CDS fruB NC_013008.1 2993527 2994657 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2993527..2994657) Escherichia coli O157:H7 str. TW14359 8217613 YP_003078906.1 CDS ECSP_3048 NC_013008.1 2994823 2994954 D hypothetical protein 2994823..2994954 Escherichia coli O157:H7 str. TW14359 8217614 YP_003078907.1 CDS setB NC_013008.1 2995025 2996206 D lactose/glucose efflux system 2995025..2996206 Escherichia coli O157:H7 str. TW14359 8217615 YP_003078908.1 CDS yeiW NC_013008.1 2996203 2996457 R hypothetical protein complement(2996203..2996457) Escherichia coli O157:H7 str. TW14359 8217616 YP_003078909.1 CDS yeiP NC_013008.1 2996612 2997184 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2996612..2997184 Escherichia coli O157:H7 str. TW14359 8217617 YP_003078910.1 CDS yeiQ NC_013008.1 2997407 2998873 D dehydrogenase, NAD-dependent 2997407..2998873 Escherichia coli O157:H7 str. TW14359 8217618 YP_003078911.1 CDS yeiR NC_013008.1 2998991 2999977 D hypothetical protein 2998991..2999977 Escherichia coli O157:H7 str. TW14359 8217619 YP_003078912.1 CDS yeiU NC_013008.1 3000016 3000729 D UDP pyrophosphate phosphatase 3000016..3000729 Escherichia coli O157:H7 str. TW14359 8217620 YP_003078913.1 CDS spr NC_013008.1 3001142 3001708 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 3001142..3001708 Escherichia coli O157:H7 str. TW14359 8217621 YP_003078914.1 CDS rtn NC_013008.1 3001889 3003445 D hypothetical protein 3001889..3003445 Escherichia coli O157:H7 str. TW14359 8217622 YP_003078915.1 CDS yejA NC_013008.1 3003527 3005341 D oligopeptide transporter subunit; periplasmic-binding component of ABC superfamily 3003527..3005341 Escherichia coli O157:H7 str. TW14359 8217623 YP_003078916.1 CDS yejB NC_013008.1 3005342 3006436 D oligopeptide ABC transporter membrane protein 3005342..3006436 Escherichia coli O157:H7 str. TW14359 8217624 YP_003078917.1 CDS yejE NC_013008.1 3006436 3007461 D oligopeptide ABC transporter membrane protein 3006436..3007461 Escherichia coli O157:H7 str. TW14359 8217625 YP_003078918.1 CDS yejF NC_013008.1 3007463 3009052 D fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding proteins 3007463..3009052 Escherichia coli O157:H7 str. TW14359 8217626 YP_003078919.1 CDS yejG NC_013008.1 3009056 3009400 R hypothetical protein complement(3009056..3009400) Escherichia coli O157:H7 str. TW14359 8217627 YP_003078920.1 CDS bcr NC_013008.1 3009733 3010923 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system complement(3009733..3010923) Escherichia coli O157:H7 str. TW14359 8217628 YP_003078921.1 CDS rsuA NC_013008.1 3010951 3011646 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(3010951..3011646) Escherichia coli O157:H7 str. TW14359 8217629 YP_003078922.1 CDS yejH NC_013008.1 3011795 3013555 D ATP-dependent helicase 3011795..3013555 Escherichia coli O157:H7 str. TW14359 8217630 YP_003078923.1 CDS rplY NC_013008.1 3013680 3013964 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3013680..3013964 Escherichia coli O157:H7 str. TW14359 8217631 YP_003078924.1 CDS yejK NC_013008.1 3014103 3015110 R nucleoid-associated protein NdpA complement(3014103..3015110) Escherichia coli O157:H7 str. TW14359 8217632 YP_003078925.1 CDS ECSP_3067 NC_013008.1 3015155 3015271 R hypothetical protein complement(3015155..3015271) Escherichia coli O157:H7 str. TW14359 8217633 YP_003078926.1 CDS yejL NC_013008.1 3015292 3015519 D hypothetical protein 3015292..3015519 Escherichia coli O157:H7 str. TW14359 8217634 YP_003078927.1 CDS yejM NC_013008.1 3015539 3017299 D hydrolase 3015539..3017299 Escherichia coli O157:H7 str. TW14359 8217635 YP_003078928.1 CDS yejO NC_013008.1 3017551 3020142 R autotransporter outer membrane protein complement(3017551..3020142) Escherichia coli O157:H7 str. TW14359 8217637 YP_003078929.1 CDS narP NC_013008.1 3020462 3021109 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 3020462..3021109 Escherichia coli O157:H7 str. TW14359 8217638 YP_003078930.1 CDS ccmH NC_013008.1 3021144 3022196 R heme lyase CcmH complement(3021144..3022196) Escherichia coli O157:H7 str. TW14359 8217639 YP_003078931.1 CDS ccmG NC_013008.1 3022193 3022750 R periplasmic thioredoxin of cytochrome c-type biogenesis complement(3022193..3022750) Escherichia coli O157:H7 str. TW14359 8217640 YP_003078932.1 CDS ccmF NC_013008.1 3022747 3024690 R heme lyase CcmF complement(3022747..3024690) Escherichia coli O157:H7 str. TW14359 8217641 YP_003078933.1 CDS ccmE NC_013008.1 3024687 3025166 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(3024687..3025166) Escherichia coli O157:H7 str. TW14359 8217642 YP_003078934.1 CDS ccmD NC_013008.1 3025163 3025372 R cytochrome c biogenesis protein complement(3025163..3025372) Escherichia coli O157:H7 str. TW14359 8217643 YP_003078935.1 CDS ccmC NC_013008.1 3025369 3026106 R heme ABC transporter membrane protein complement(3025369..3026106) Escherichia coli O157:H7 str. TW14359 8217644 YP_003078936.1 CDS ccmB NC_013008.1 3026148 3026810 R heme ABC transporter membrane protein complement(3026148..3026810) Escherichia coli O157:H7 str. TW14359 8217645 YP_003078937.1 CDS ccmA NC_013008.1 3026807 3027430 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(3026807..3027430) Escherichia coli O157:H7 str. TW14359 8217646 YP_003078938.1 CDS napC NC_013008.1 3027443 3028045 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(3027443..3028045) Escherichia coli O157:H7 str. TW14359 8217647 YP_003078939.1 CDS napB NC_013008.1 3028055 3028504 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(3028055..3028504) Escherichia coli O157:H7 str. TW14359 8217648 YP_003078940.1 CDS napH NC_013008.1 3028501 3029364 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(3028501..3029364) Escherichia coli O157:H7 str. TW14359 8217649 YP_003078941.1 CDS napG NC_013008.1 3029351 3030046 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(3029351..3030046) Escherichia coli O157:H7 str. TW14359 8217650 YP_003078942.1 CDS napA NC_013008.1 3030053 3032539 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(3030053..3032539) Escherichia coli O157:H7 str. TW14359 8217651 YP_003078943.1 CDS napD NC_013008.1 3032536 3032799 R assembly protein for periplasmic nitrate reductase complement(3032536..3032799) Escherichia coli O157:H7 str. TW14359 8217652 YP_003078944.1 CDS napF NC_013008.1 3032789 3033283 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(3032789..3033283) Escherichia coli O157:H7 str. TW14359 8217653 YP_003078945.1 CDS eco NC_013008.1 3033690 3034178 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 3033690..3034178 Escherichia coli O157:H7 str. TW14359 8217654 YP_003078946.1 CDS mqo NC_013008.1 3034328 3035974 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(3034328..3035974) Escherichia coli O157:H7 str. TW14359 8217655 YP_003078947.1 CDS ECSP_3090 NC_013008.1 3036192 3037835 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding protein complement(3036192..3037835) Escherichia coli O157:H7 str. TW14359 8217656 YP_003078948.1 CDS alkB NC_013008.1 3037911 3038561 R N1-methyladenine or N3-methylcytosine DNA lesion oxidative demethylase complement(3037911..3038561) Escherichia coli O157:H7 str. TW14359 8217657 YP_003078949.1 CDS ada NC_013008.1 3038561 3039625 R fused DNA-binding transcriptional dual regulator, O6-methylguanine-DNA methyltransferase complement(3038561..3039625) Escherichia coli O157:H7 str. TW14359 8217658 YP_003078950.1 CDS yojL NC_013008.1 3039699 3040754 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(3039699..3040754) Escherichia coli O157:H7 str. TW14359 8217659 YP_003078951.1 CDS ompC NC_013008.1 3040866 3041969 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(3040866..3041969) Escherichia coli O157:H7 str. TW14359 8217660 YP_003078952.1 CDS ECSP_3095 NC_013008.1 3042361 3042486 R hypothetical protein complement(3042361..3042486) Escherichia coli O157:H7 str. TW14359 8217661 YP_003078953.1 CDS rcsD NC_013008.1 3042708 3045380 D phosphotransfer intermediate protein in two-component regulatory system with RcsBC 3042708..3045380 Escherichia coli O157:H7 str. TW14359 8217662 YP_003078954.1 CDS rcsB NC_013008.1 3045397 3046047 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 3045397..3046047 Escherichia coli O157:H7 str. TW14359 8217663 YP_003078955.1 CDS rcsC NC_013008.1 3046247 3049096 R hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(3046247..3049096) Escherichia coli O157:H7 str. TW14359 8217664 YP_003078956.1 CDS yfaP NC_013008.1 3049371 3050147 R hypothetical protein complement(3049371..3050147) Escherichia coli O157:H7 str. TW14359 8217665 YP_003078957.1 CDS ECSP_3101 NC_013008.1 3051802 3056406 R hypothetical protein complement(3051802..3056406) Escherichia coli O157:H7 str. TW14359 8217667 YP_003078958.1 CDS yfaT NC_013008.1 3056340 3056963 R hypothetical protein complement(3056340..3056963) Escherichia coli O157:H7 str. TW14359 8217668 YP_003078959.1 CDS gyrA NC_013008.1 3058796 3061423 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(3058796..3061423) Escherichia coli O157:H7 str. TW14359 8217670 YP_003078960.1 CDS ubiG NC_013008.1 3061570 3062292 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 3061570..3062292 Escherichia coli O157:H7 str. TW14359 8217671 YP_003078961.1 CDS yfaL NC_013008.1 3062433 3066185 R adhesin complement(3062433..3066185) Escherichia coli O157:H7 str. TW14359 8217672 YP_003078962.1 CDS nrdA NC_013008.1 3066881 3069166 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3066881..3069166 Escherichia coli O157:H7 str. TW14359 8217673 YP_003078963.1 CDS nrdB NC_013008.1 3069393 3070523 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 3069393..3070523 Escherichia coli O157:H7 str. TW14359 8217674 YP_003078964.1 CDS yfaE NC_013008.1 3070523 3070777 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 3070523..3070777 Escherichia coli O157:H7 str. TW14359 8217675 YP_003078965.1 CDS inaA NC_013008.1 3070831 3071481 R hypothetical protein complement(3070831..3071481) Escherichia coli O157:H7 str. TW14359 8217676 YP_003078966.1 CDS ECSP_3111 NC_013008.1 3071562 3072752 R antibiotic efflux protein complement(3071562..3072752) Escherichia coli O157:H7 str. TW14359 8217677 YP_003078967.1 CDS ECSP_3112 NC_013008.1 3072904 3073782 D regulator 3072904..3073782 Escherichia coli O157:H7 str. TW14359 8217678 YP_003078968.1 CDS ECSP_3113 NC_013008.1 3074246 3075316 D hypothetical protein 3074246..3075316 Escherichia coli O157:H7 str. TW14359 8217679 YP_003078969.1 CDS glpQ NC_013008.1 3075540 3076616 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(3075540..3076616) Escherichia coli O157:H7 str. TW14359 8217680 YP_003078970.1 CDS glpT NC_013008.1 3076621 3077979 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(3076621..3077979) Escherichia coli O157:H7 str. TW14359 8217681 YP_003078971.1 CDS glpA NC_013008.1 3078252 3079880 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 3078252..3079880 Escherichia coli O157:H7 str. TW14359 8217682 YP_003078972.1 CDS glpB NC_013008.1 3079870 3081129 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 3079870..3081129 Escherichia coli O157:H7 str. TW14359 8217683 YP_003078973.1 CDS glpC NC_013008.1 3081126 3082316 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 3081126..3082316 Escherichia coli O157:H7 str. TW14359 8217684 YP_003078974.1 CDS yfaD NC_013008.1 3082509 3083435 D hypothetical protein 3082509..3083435 Escherichia coli O157:H7 str. TW14359 8217685 YP_003078975.1 CDS yfaU NC_013008.1 3083476 3084228 R aldolase complement(3083476..3084228) Escherichia coli O157:H7 str. TW14359 8217686 YP_003078976.1 CDS yfaV NC_013008.1 3084296 3085054 R transporter complement(3084296..3085054) Escherichia coli O157:H7 str. TW14359 8217687 YP_003078977.1 CDS ECSP_3122 NC_013008.1 3085125 3085451 D transposase 3085125..3085451 Escherichia coli O157:H7 str. TW14359 8217688 YP_003078978.1 CDS ECSP_3123 NC_013008.1 3085448 3086338 D transposase 3085448..3086338 Escherichia coli O157:H7 str. TW14359 8217689 YP_003078979.1 CDS yfaW NC_013008.1 3086955 3088172 R enolase complement(3086955..3088172) Escherichia coli O157:H7 str. TW14359 8217690 YP_003078980.1 CDS yfaX NC_013008.1 3088175 3088957 R DNA-binding transcriptional regulator complement(3088175..3088957) Escherichia coli O157:H7 str. TW14359 8217691 YP_003078981.1 CDS yfaY NC_013008.1 3089177 3090379 R competence damage-inducible protein A complement(3089177..3090379) Escherichia coli O157:H7 str. TW14359 8217692 YP_003078982.1 CDS yfaZ NC_013008.1 3090479 3091021 R outer membrane porin protein complement(3090479..3091021) Escherichia coli O157:H7 str. TW14359 8217693 YP_003078983.1 CDS yfaO NC_013008.1 3091300 3091725 D hypothetical protein 3091300..3091725 Escherichia coli O157:H7 str. TW14359 8217694 YP_003078984.1 CDS ais NC_013008.1 3091764 3092366 R hypothetical protein complement(3091764..3092366) Escherichia coli O157:H7 str. TW14359 8217695 YP_003078985.1 CDS arnB NC_013008.1 3092674 3093813 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 3092674..3093813 Escherichia coli O157:H7 str. TW14359 8217696 YP_003078986.1 CDS arnC NC_013008.1 3093817 3094785 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; UDP phosphate 4-deoxy-4-formamido-L-arabinose transferase 3093817..3094785 Escherichia coli O157:H7 str. TW14359 8217697 YP_003078987.1 CDS arnA NC_013008.1 3094785 3096767 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 3094785..3096767 Escherichia coli O157:H7 str. TW14359 8217698 YP_003078988.1 CDS yfbH NC_013008.1 3096764 3097654 D hypothetical protein 3096764..3097654 Escherichia coli O157:H7 str. TW14359 8217699 YP_003078989.1 CDS arnT NC_013008.1 3097654 3099306 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 3097654..3099306 Escherichia coli O157:H7 str. TW14359 8217700 YP_003078990.1 CDS yfbW NC_013008.1 3099303 3099638 D hypothetical protein 3099303..3099638 Escherichia coli O157:H7 str. TW14359 8217701 YP_003078991.1 CDS yfbJ NC_013008.1 3099638 3100024 D hypothetical protein 3099638..3100024 Escherichia coli O157:H7 str. TW14359 8217702 YP_003078992.1 CDS pmrD NC_013008.1 3100018 3100284 R polymyxin resistance protein B complement(3100018..3100284) Escherichia coli O157:H7 str. TW14359 8217703 YP_003078993.1 CDS menE NC_013008.1 3100394 3101749 R O-succinylbenzoic acid--CoA ligase complement(3100394..3101749) Escherichia coli O157:H7 str. TW14359 8217704 YP_003078994.1 CDS menC NC_013008.1 3101746 3102708 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(3101746..3102708) Escherichia coli O157:H7 str. TW14359 8217705 YP_003078995.1 CDS menB NC_013008.1 3102708 3103565 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(3102708..3103565) Escherichia coli O157:H7 str. TW14359 8217706 YP_003078996.1 CDS yfbB NC_013008.1 3103580 3104338 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(3103580..3104338) Escherichia coli O157:H7 str. TW14359 8217707 YP_003078997.1 CDS menD NC_013008.1 3104335 3106005 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(3104335..3106005) Escherichia coli O157:H7 str. TW14359 8217708 YP_003078998.1 CDS menF NC_013008.1 3106094 3107389 R isochorismate synthase 2 complement(3106094..3107389) Escherichia coli O157:H7 str. TW14359 8217709 YP_003078999.1 CDS elaB NC_013008.1 3107468 3107773 R hypothetical protein complement(3107468..3107773) Escherichia coli O157:H7 str. TW14359 8217710 YP_003079000.1 CDS elaA NC_013008.1 3107828 3108289 R hypothetical protein complement(3107828..3108289) Escherichia coli O157:H7 str. TW14359 8217711 YP_003079001.1 CDS rbn NC_013008.1 3108354 3109271 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 3108354..3109271 Escherichia coli O157:H7 str. TW14359 8217712 YP_003079002.1 CDS elaD NC_013008.1 3109459 3110682 D ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 3109459..3110682 Escherichia coli O157:H7 str. TW14359 8217713 YP_003079003.1 CDS yfbL NC_013008.1 3111469 3111711 D peptidase 3111469..3111711 Escherichia coli O157:H7 str. TW14359 8217714 YP_003079004.1 CDS yfbM NC_013008.1 3111814 3112317 D hypothetical protein 3111814..3112317 Escherichia coli O157:H7 str. TW14359 8217715 YP_003079005.1 CDS nuoN NC_013008.1 3112384 3113841 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(3112384..3113841) Escherichia coli O157:H7 str. TW14359 8217716 YP_003079006.1 CDS nuoM NC_013008.1 3113848 3115377 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(3113848..3115377) Escherichia coli O157:H7 str. TW14359 8217717 YP_003079007.1 CDS nuoL NC_013008.1 3115608 3117449 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(3115608..3117449) Escherichia coli O157:H7 str. TW14359 8217718 YP_003079008.1 CDS nuoK NC_013008.1 3117446 3117748 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(3117446..3117748) Escherichia coli O157:H7 str. TW14359 8217719 YP_003079009.1 CDS nuoJ NC_013008.1 3117745 3118299 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(3117745..3118299) Escherichia coli O157:H7 str. TW14359 8217720 YP_003079010.1 CDS nuoI NC_013008.1 3118311 3118853 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(3118311..3118853) Escherichia coli O157:H7 str. TW14359 8217721 YP_003079011.1 CDS nuoH NC_013008.1 3118868 3119845 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(3118868..3119845) Escherichia coli O157:H7 str. TW14359 8217722 YP_003079012.1 CDS nuoG NC_013008.1 3119842 3122568 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(3119842..3122568) Escherichia coli O157:H7 str. TW14359 8217723 YP_003079013.1 CDS nuoF NC_013008.1 3122621 3123958 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(3122621..3123958) Escherichia coli O157:H7 str. TW14359 8217724 YP_003079014.1 CDS nuoE NC_013008.1 3123955 3124455 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(3123955..3124455) Escherichia coli O157:H7 str. TW14359 8217725 YP_003079015.1 CDS nuoC NC_013008.1 3124458 3126248 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(3124458..3126248) Escherichia coli O157:H7 str. TW14359 8217726 YP_003079016.1 CDS nuoB NC_013008.1 3126354 3127016 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(3126354..3127016) Escherichia coli O157:H7 str. TW14359 8217727 YP_003079017.1 CDS nuoA NC_013008.1 3127032 3127475 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(3127032..3127475) Escherichia coli O157:H7 str. TW14359 8217728 YP_003079018.1 CDS lrhA NC_013008.1 3128106 3129044 R DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes complement(3128106..3129044) Escherichia coli O157:H7 str. TW14359 8217729 YP_003079019.1 CDS yfbQ NC_013008.1 3129964 3131181 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 3129964..3131181 Escherichia coli O157:H7 str. TW14359 8217730 YP_003079020.1 CDS yfbR NC_013008.1 3131265 3131864 D hypothetical protein 3131265..3131864 Escherichia coli O157:H7 str. TW14359 8217731 YP_003079021.1 CDS yfbS NC_013008.1 3131923 3133755 R transporter complement(3131923..3133755) Escherichia coli O157:H7 str. TW14359 8217732 YP_003079022.1 CDS yfbT NC_013008.1 3133842 3134492 R phosphatase complement(3133842..3134492) Escherichia coli O157:H7 str. TW14359 8217733 YP_003079023.1 CDS yfbU NC_013008.1 3134503 3134997 R hypothetical protein complement(3134503..3134997) Escherichia coli O157:H7 str. TW14359 8217734 YP_003079024.1 CDS yfbV NC_013008.1 3135080 3135535 R hypothetical protein complement(3135080..3135535) Escherichia coli O157:H7 str. TW14359 8217735 YP_003079025.1 CDS ECSP_3170 NC_013008.1 3135604 3135735 R hypothetical protein complement(3135604..3135735) Escherichia coli O157:H7 str. TW14359 8217736 YP_003079026.1 CDS ackA NC_013008.1 3135873 3137075 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 3135873..3137075 Escherichia coli O157:H7 str. TW14359 8217737 YP_003079027.1 CDS pta NC_013008.1 3137150 3139294 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 3137150..3139294 Escherichia coli O157:H7 str. TW14359 8217738 YP_003079028.1 CDS yfcC NC_013008.1 3139484 3141004 D hypothetical protein 3139484..3141004 Escherichia coli O157:H7 str. TW14359 8217739 YP_003079029.1 CDS yfcD NC_013008.1 3141037 3141579 R NUDIX hydrolase complement(3141037..3141579) Escherichia coli O157:H7 str. TW14359 8217740 YP_003079030.1 CDS yfcE NC_013008.1 3141637 3142191 R phosphodiesterase complement(3141637..3142191) Escherichia coli O157:H7 str. TW14359 8217741 YP_003079031.1 CDS yfcF NC_013008.1 3142244 3142888 R hypothetical protein complement(3142244..3142888) Escherichia coli O157:H7 str. TW14359 8217742 YP_003079032.1 CDS yfcG NC_013008.1 3143024 3143671 D glutathione S-transferase 3143024..3143671 Escherichia coli O157:H7 str. TW14359 8217743 YP_003079033.1 CDS folX NC_013008.1 3143728 3144090 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 3143728..3144090 Escherichia coli O157:H7 str. TW14359 8217744 YP_003079034.1 CDS yfcH NC_013008.1 3144111 3145004 D hypothetical protein 3144111..3145004 Escherichia coli O157:H7 str. TW14359 8217745 YP_003079035.1 CDS yfcI NC_013008.1 3145052 3145942 R transposase complement(3145052..3145942) Escherichia coli O157:H7 str. TW14359 8217746 YP_003079036.1 CDS hisP NC_013008.1 3146139 3146912 R histidine/lysine/arginine/ornithine transporter subunit complement(3146139..3146912) Escherichia coli O157:H7 str. TW14359 8217747 YP_003079037.1 CDS hisM NC_013008.1 3146920 3147636 R histidine/lysine/arginine/ornithine ABC transporter membrane protein complement(3146920..3147636) Escherichia coli O157:H7 str. TW14359 8217748 YP_003079038.1 CDS hisQ NC_013008.1 3147633 3148319 R histidine/lysine/arginine/ornithine ABC transporter membrane protein complement(3147633..3148319) Escherichia coli O157:H7 str. TW14359 8217749 YP_003079039.1 CDS hisJ NC_013008.1 3148409 3149191 R histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein complement(3148409..3149191) Escherichia coli O157:H7 str. TW14359 8217750 YP_003079040.1 CDS argT NC_013008.1 3149412 3150194 R lysine/arginine/ornithine ABC transporter periplasmic-binding protein complement(3149412..3150194) Escherichia coli O157:H7 str. TW14359 8217751 YP_003079041.1 CDS ubiX NC_013008.1 3150460 3151029 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(3150460..3151029) Escherichia coli O157:H7 str. TW14359 8217752 YP_003079042.1 CDS purF NC_013008.1 3151124 3152641 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(3151124..3152641) Escherichia coli O157:H7 str. TW14359 8217753 YP_003079043.1 CDS cvpA NC_013008.1 3152678 3153166 R membrane protein required for colicin V production; colicin V production protein complement(3152678..3153166) Escherichia coli O157:H7 str. TW14359 8217754 YP_003079044.1 CDS dedD NC_013008.1 3153698 3154360 R hypothetical protein complement(3153698..3154360) Escherichia coli O157:H7 str. TW14359 8217755 YP_003079045.1 CDS folC NC_013008.1 3154350 3155618 R bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(3154350..3155618) Escherichia coli O157:H7 str. TW14359 8217756 YP_003079046.1 CDS accD NC_013008.1 3155688 3156602 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(3155688..3156602) Escherichia coli O157:H7 str. TW14359 8217757 YP_003079047.1 CDS dedA NC_013008.1 3156758 3157417 R hypothetical protein complement(3156758..3157417) Escherichia coli O157:H7 str. TW14359 8217758 YP_003079048.1 CDS truA NC_013008.1 3157500 3158312 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(3157500..3158312) Escherichia coli O157:H7 str. TW14359 8217759 YP_003079049.1 CDS usg NC_013008.1 3158312 3159325 R semialdehyde dehydrogenase complement(3158312..3159325) Escherichia coli O157:H7 str. TW14359 8217760 YP_003079050.1 CDS pdxB NC_013008.1 3159391 3160527 R erythronate-4-phosphate dehydrogenase complement(3159391..3160527) Escherichia coli O157:H7 str. TW14359 8217761 YP_003079051.1 CDS flk NC_013008.1 3160626 3161621 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 3160626..3161621 Escherichia coli O157:H7 str. TW14359 8217762 YP_003079052.1 CDS yfcJ NC_013008.1 3161618 3162796 R hypothetical protein complement(3161618..3162796) Escherichia coli O157:H7 str. TW14359 8217763 YP_003079053.1 CDS fabB NC_013008.1 3163071 3164291 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(3163071..3164291) Escherichia coli O157:H7 str. TW14359 8217764 YP_003079054.1 CDS mnmC NC_013008.1 3164450 3166456 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 3164450..3166456 Escherichia coli O157:H7 str. TW14359 8217765 YP_003079055.1 CDS yfcL NC_013008.1 3166577 3166855 R hypothetical protein complement(3166577..3166855) Escherichia coli O157:H7 str. TW14359 8217766 YP_003079056.1 CDS yfcM NC_013008.1 3166889 3167437 R hypothetical protein complement(3166889..3167437) Escherichia coli O157:H7 str. TW14359 8217767 YP_003079057.1 CDS yfcA NC_013008.1 3167437 3168246 R hypothetical protein complement(3167437..3168246) Escherichia coli O157:H7 str. TW14359 8217768 YP_003079058.1 CDS mepA NC_013008.1 3168246 3169070 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(3168246..3169070) Escherichia coli O157:H7 str. TW14359 8217769 YP_003079059.1 CDS aroC NC_013008.1 3169074 3170159 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(3169074..3170159) Escherichia coli O157:H7 str. TW14359 8217770 YP_003079060.1 CDS prmB NC_013008.1 3170194 3171126 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(3170194..3171126) Escherichia coli O157:H7 str. TW14359 8217771 YP_003079061.1 CDS yfcN NC_013008.1 3171292 3171843 D hypothetical protein 3171292..3171843 Escherichia coli O157:H7 str. TW14359 8217772 YP_003079062.1 CDS ECSP_3207 NC_013008.1 3172014 3172856 R hypothetical protein complement(3172014..3172856) Escherichia coli O157:H7 str. TW14359 8217773 YP_003079063.1 CDS ECSP_3208 NC_013008.1 3172858 3173379 R minor fimbrial subunit complement(3172858..3173379) Escherichia coli O157:H7 str. TW14359 8217774 YP_003079064.1 CDS ECSP_3209 NC_013008.1 3173782 3174252 R minor fimbrial subunit complement(3173782..3174252) Escherichia coli O157:H7 str. TW14359 8217775 YP_003079065.1 CDS ECSP_3210 NC_013008.1 3174249 3174749 R minor fimbrial subunit complement(3174249..3174749) Escherichia coli O157:H7 str. TW14359 8217776 YP_003079066.1 CDS yfcS NC_013008.1 3174760 3175518 R periplasmic pilus chaperone complement(3174760..3175518) Escherichia coli O157:H7 str. TW14359 8217777 YP_003079067.1 CDS yfcU NC_013008.1 3175541 3178180 R fimbrial usher complement(3175541..3178180) Escherichia coli O157:H7 str. TW14359 8217778 YP_003079068.1 CDS yfcV NC_013008.1 3178262 3178825 R fimbrial-like adhesin protein complement(3178262..3178825) Escherichia coli O157:H7 str. TW14359 8217779 YP_003079069.1 CDS sixA NC_013008.1 3179471 3179956 R phosphohistidine phosphatase complement(3179471..3179956) Escherichia coli O157:H7 str. TW14359 8217780 YP_003079070.1 CDS fadJ NC_013008.1 3180159 3182303 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(3180159..3182303) Escherichia coli O157:H7 str. TW14359 8217781 YP_003079071.1 CDS fadI NC_013008.1 3182303 3183613 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(3182303..3183613) Escherichia coli O157:H7 str. TW14359 8217782 YP_003079072.1 CDS yfcZ NC_013008.1 3183793 3184077 R hypothetical protein complement(3183793..3184077) Escherichia coli O157:H7 str. TW14359 8217783 YP_003079073.1 CDS fadL NC_013008.1 3184449 3185789 D long-chain fatty acid outer membrane transporter 3184449..3185789 Escherichia coli O157:H7 str. TW14359 8217784 YP_003079074.1 CDS yfdF NC_013008.1 3186154 3187185 D hypothetical protein 3186154..3187185 Escherichia coli O157:H7 str. TW14359 8217785 YP_003079075.1 CDS vacJ NC_013008.1 3187580 3188335 R lipoprotein complement(3187580..3188335) Escherichia coli O157:H7 str. TW14359 8217786 YP_003079076.1 CDS yfdC NC_013008.1 3188629 3189561 D inner membrane protein 3188629..3189561 Escherichia coli O157:H7 str. TW14359 8217787 YP_003079077.1 CDS ECSP_3222 NC_013008.1 3189783 3198158 R hypothetical protein complement(3189783..3198158) Escherichia coli O157:H7 str. TW14359 8217788 YP_003079078.1 CDS ECSP_3223 NC_013008.1 3198227 3199492 R hypothetical protein complement(3198227..3199492) Escherichia coli O157:H7 str. TW14359 8217789 YP_003079079.1 CDS ECSP_3224 NC_013008.1 3199503 3199796 R hypothetical protein complement(3199503..3199796) Escherichia coli O157:H7 str. TW14359 8217790 YP_003079080.1 CDS ECSP_3225 NC_013008.1 3199806 3200252 R hypothetical protein complement(3199806..3200252) Escherichia coli O157:H7 str. TW14359 8217791 YP_003079081.1 CDS ECSP_3226 NC_013008.1 3200255 3200911 R hypothetical protein complement(3200255..3200911) Escherichia coli O157:H7 str. TW14359 8217792 YP_003079082.1 CDS ECSP_3227 NC_013008.1 3201006 3201407 R hypothetical protein complement(3201006..3201407) Escherichia coli O157:H7 str. TW14359 8217793 YP_003079083.1 CDS lomW NC_013008.1 3201835 3202569 R outer membrane protein Lom complement(3201835..3202569) Escherichia coli O157:H7 str. TW14359 8217794 YP_003079084.1 CDS ECSP_3229 NC_013008.1 3202660 3203277 R hypothetical protein complement(3202660..3203277) Escherichia coli O157:H7 str. TW14359 8217795 YP_003079085.1 CDS ECSP_3230 NC_013008.1 3203576 3204844 R hypothetical protein complement(3203576..3204844) Escherichia coli O157:H7 str. TW14359 8217796 YP_003079086.1 CDS ECSP_3231 NC_013008.1 3204841 3206544 R hypothetical protein complement(3204841..3206544) Escherichia coli O157:H7 str. TW14359 8217797 YP_003079087.1 CDS ECSP_3232 NC_013008.1 3206761 3207003 R hypothetical protein complement(3206761..3207003) Escherichia coli O157:H7 str. TW14359 8217798 YP_003079088.1 CDS ECSP_3233 NC_013008.1 3207088 3207357 R tail fiber protein of bacteriophage BP-933W complement(3207088..3207357) Escherichia coli O157:H7 str. TW14359 8217799 YP_003079089.1 CDS ECSP_3234 NC_013008.1 3207359 3209296 R tail fiber protein of bacteriophage BP-933W complement(3207359..3209296) Escherichia coli O157:H7 str. TW14359 8217800 YP_003079090.1 CDS ECSP_3235 NC_013008.1 3209293 3209943 R hypothetical protein complement(3209293..3209943) Escherichia coli O157:H7 str. TW14359 8217801 YP_003079091.1 CDS ECSP_3236 NC_013008.1 3210490 3210951 R hypothetical protein complement(3210490..3210951) Escherichia coli O157:H7 str. TW14359 8217802 YP_003079092.1 CDS ECSP_3237 NC_013008.1 3211001 3211390 R hypothetical protein complement(3211001..3211390) Escherichia coli O157:H7 str. TW14359 8217803 YP_003079093.1 CDS ECSP_3238 NC_013008.1 3211446 3212660 R hypothetical protein complement(3211446..3212660) Escherichia coli O157:H7 str. TW14359 8217804 YP_003079094.1 CDS ECSP_3239 NC_013008.1 3213231 3213557 D transposase 3213231..3213557 Escherichia coli O157:H7 str. TW14359 8217805 YP_003079095.1 CDS ECSP_3240 NC_013008.1 3213554 3214444 D transposase 3213554..3214444 Escherichia coli O157:H7 str. TW14359 8217806 YP_003079096.1 CDS ECSP_3241 NC_013008.1 3214447 3215004 R hypothetical protein complement(3214447..3215004) Escherichia coli O157:H7 str. TW14359 8217807 YP_003079097.1 CDS ECSP_3242 NC_013008.1 3215162 3217306 R portal protein of bacteriophage BP-933W complement(3215162..3217306) Escherichia coli O157:H7 str. TW14359 8217808 YP_003079098.1 CDS ECSP_3243 NC_013008.1 3217306 3219012 R terminase large subunit of bacteriophage BP-933W complement(3217306..3219012) Escherichia coli O157:H7 str. TW14359 8217809 YP_003079099.1 CDS ECSP_3244 NC_013008.1 3218993 3219799 R terminase small subunit of bacteriophage BP-933W complement(3218993..3219799) Escherichia coli O157:H7 str. TW14359 8217810 YP_003079100.1 CDS borW NC_013008.1 3220208 3220501 D Bor protein 3220208..3220501 Escherichia coli O157:H7 str. TW14359 8217811 YP_003079101.1 CDS rz NC_013008.1 3220533 3220997 R lysis protein Rz complement(3220533..3220997) Escherichia coli O157:H7 str. TW14359 8217812 YP_003079102.1 CDS ECSP_3247 NC_013008.1 3221005 3221139 R hypothetical protein complement(3221005..3221139) Escherichia coli O157:H7 str. TW14359 8217813 YP_003079103.1 CDS ant NC_013008.1 3221154 3221723 R antirepressor protein Ant complement(3221154..3221723) Escherichia coli O157:H7 str. TW14359 8217814 YP_003079104.1 CDS r NC_013008.1 3221997 3222530 R endolysin R complement(3221997..3222530) Escherichia coli O157:H7 str. TW14359 8217815 YP_003079105.1 CDS ECSP_3250 NC_013008.1 3222827 3223273 R hypothetical protein complement(3222827..3223273) Escherichia coli O157:H7 str. TW14359 8217816 YP_003079106.1 CDS ECSP_3251 NC_013008.1 3223454 3225391 R hypothetical protein complement(3223454..3225391) Escherichia coli O157:H7 str. TW14359 8217817 YP_003079107.1 CDS stx2B NC_013008.1 3225878 3226147 R shiga toxin II subunit B complement(3225878..3226147) Escherichia coli O157:H7 str. TW14359 8217818 YP_003079108.1 CDS stx2A2 NC_013008.1 3226159 3227118 R shiga toxin II subunit A complement(3226159..3227118) Escherichia coli O157:H7 str. TW14359 8217819 YP_003079109.1 CDS q NC_013008.1 3227900 3228334 R antitermination protein Q of bacteriophage BP-933W complement(3227900..3228334) Escherichia coli O157:H7 str. TW14359 8217823 YP_003079110.1 CDS ninG NC_013008.1 3228518 3229123 R NinG protein complement(3228518..3229123) Escherichia coli O157:H7 str. TW14359 8217824 YP_003079111.1 CDS roi NC_013008.1 3229123 3229845 R DNA-binding protein Roi complement(3229123..3229845) Escherichia coli O157:H7 str. TW14359 8217825 YP_003079112.1 CDS ECSP_3260 NC_013008.1 3230007 3230408 R hypothetical protein complement(3230007..3230408) Escherichia coli O157:H7 str. TW14359 8217826 YP_003079113.1 CDS ECSP_3261 NC_013008.1 3230483 3231157 R antirepressor protein complement(3230483..3231157) Escherichia coli O157:H7 str. TW14359 8217827 YP_003079114.1 CDS ninE NC_013008.1 3231414 3231608 R NinE protein complement(3231414..3231608) Escherichia coli O157:H7 str. TW14359 8217828 YP_003079115.1 CDS ECSP_3263 NC_013008.1 3231605 3232132 R DNA N-6-adenine-methyltransferase of bacteriophage BP-933W complement(3231605..3232132) Escherichia coli O157:H7 str. TW14359 8217829 YP_003079116.1 CDS ECSP_3264 NC_013008.1 3232129 3232731 R endonuclease complement(3232129..3232731) Escherichia coli O157:H7 str. TW14359 8217830 YP_003079117.1 CDS ninB NC_013008.1 3232724 3233140 R NinB protein complement(3232724..3233140) Escherichia coli O157:H7 str. TW14359 8217831 YP_003079118.1 CDS ECSP_3266 NC_013008.1 3233662 3233940 R hypothetical protein complement(3233662..3233940) Escherichia coli O157:H7 str. TW14359 8217832 YP_003079119.1 CDS ren NC_013008.1 3234011 3234301 R Ren protein complement(3234011..3234301) Escherichia coli O157:H7 str. TW14359 8217833 YP_003079120.1 CDS p NC_013008.1 3234298 3234999 R replication protein P of bacteriophage BP-933W complement(3234298..3234999) Escherichia coli O157:H7 str. TW14359 8217834 YP_003079121.1 CDS o NC_013008.1 3234996 3235934 R replication protein O complement(3234996..3235934) Escherichia coli O157:H7 str. TW14359 8217835 YP_003079122.1 CDS cII NC_013008.1 3235967 3236263 R regulatory protein CII of bacteriophage BP-933W complement(3235967..3236263) Escherichia coli O157:H7 str. TW14359 8217836 YP_003079123.1 CDS cro NC_013008.1 3236402 3236629 R regulatory protein Cro complement(3236402..3236629) Escherichia coli O157:H7 str. TW14359 8217837 YP_003079124.1 CDS cI NC_013008.1 3236708 3237415 D repressor protein CI 3236708..3237415 Escherichia coli O157:H7 str. TW14359 8217838 YP_003079125.1 CDS ECSP_3273 NC_013008.1 3237476 3237817 D hypothetical protein 3237476..3237817 Escherichia coli O157:H7 str. TW14359 8217839 YP_003079126.1 CDS ECSP_3274 NC_013008.1 3237885 3238346 D hypothetical protein 3237885..3238346 Escherichia coli O157:H7 str. TW14359 8217840 YP_003079127.1 CDS ECSP_3275 NC_013008.1 3238340 3239386 D serine/threonine kinase encoded by bacteriophage BP-933W 3238340..3239386 Escherichia coli O157:H7 str. TW14359 8217841 YP_003079128.1 CDS ECSP_3276 NC_013008.1 3239389 3239553 D hypothetical protein 3239389..3239553 Escherichia coli O157:H7 str. TW14359 8217842 YP_003079129.1 CDS n NC_013008.1 3240042 3240425 D antitermination protein N of bacteriophage BP-933W 3240042..3240425 Escherichia coli O157:H7 str. TW14359 8217843 YP_003079130.1 CDS ECSP_3278 NC_013008.1 3240484 3240954 D hypothetical protein 3240484..3240954 Escherichia coli O157:H7 str. TW14359 8217844 YP_003079131.1 CDS ssbW NC_013008.1 3241105 3241473 D single-stranded DNA binding protein 3241105..3241473 Escherichia coli O157:H7 str. TW14359 8217845 YP_003079132.1 CDS kilW NC_013008.1 3241553 3241843 D Kil protein of bacteriphage BP-933W 3241553..3241843 Escherichia coli O157:H7 str. TW14359 8217846 YP_003079133.1 CDS gamW NC_013008.1 3241898 3242194 D host-nuclease inhibitor protein Gam 3241898..3242194 Escherichia coli O157:H7 str. TW14359 8217847 YP_003079134.1 CDS betW NC_013008.1 3242200 3242985 D Bet recombination protein 3242200..3242985 Escherichia coli O157:H7 str. TW14359 8217848 YP_003079135.1 CDS exoW NC_013008.1 3242982 3243662 D exonuclease 3242982..3243662 Escherichia coli O157:H7 str. TW14359 8217849 YP_003079136.1 CDS ECSP_3284 NC_013008.1 3244016 3244297 D hypothetical protein 3244016..3244297 Escherichia coli O157:H7 str. TW14359 8217850 YP_003079137.1 CDS ECSP_3285 NC_013008.1 3244614 3245561 D hypothetical protein 3244614..3245561 Escherichia coli O157:H7 str. TW14359 8217851 YP_003079138.1 CDS ECSP_3286 NC_013008.1 3245563 3246069 D heme binding virulence factor 3245563..3246069 Escherichia coli O157:H7 str. TW14359 8217852 YP_003079139.1 CDS ECSP_3287 NC_013008.1 3246131 3246427 R hypothetical protein complement(3246131..3246427) Escherichia coli O157:H7 str. TW14359 8217853 YP_003079140.1 CDS ECSP_3288 NC_013008.1 3246466 3246753 D hypothetical protein 3246466..3246753 Escherichia coli O157:H7 str. TW14359 8217854 YP_003079141.1 CDS ECSP_3289 NC_013008.1 3246757 3247374 D hypothetical protein 3246757..3247374 Escherichia coli O157:H7 str. TW14359 8217855 YP_003079142.1 CDS ECSP_3290 NC_013008.1 3247651 3247749 D hypothetical protein 3247651..3247749 Escherichia coli O157:H7 str. TW14359 8217856 YP_003079143.1 CDS antB NC_013008.1 3247984 3248637 D phage anti-repressor protein AntB 3247984..3248637 Escherichia coli O157:H7 str. TW14359 8217857 YP_003079144.1 CDS ECSP_3292 NC_013008.1 3248680 3248847 D hypothetical protein 3248680..3248847 Escherichia coli O157:H7 str. TW14359 8217858 YP_003079145.1 CDS ECSP_3293 NC_013008.1 3249074 3249700 D adenine methylase 3249074..3249700 Escherichia coli O157:H7 str. TW14359 8217859 YP_003079146.1 CDS ECSP_3294 NC_013008.1 3249660 3249872 D hypothetical protein 3249660..3249872 Escherichia coli O157:H7 str. TW14359 8217860 YP_003079147.1 CDS ECSP_3295 NC_013008.1 3249908 3250285 D hypothetical protein 3249908..3250285 Escherichia coli O157:H7 str. TW14359 8217861 YP_003079148.1 CDS ECSP_3296 NC_013008.1 3250364 3250546 D hypothetical protein 3250364..3250546 Escherichia coli O157:H7 str. TW14359 8217862 YP_003079149.1 CDS intW NC_013008.1 3250530 3251699 R integrase complement(3250530..3251699) Escherichia coli O157:H7 str. TW14359 8217863 YP_003079150.1 CDS intS NC_013008.1 3252131 3253288 D CPS-53 (KpLE1) prophage; prophage CPS-53 integrase 3252131..3253288 Escherichia coli O157:H7 str. TW14359 8217865 YP_003079151.1 CDS ECSP_3300 NC_013008.1 3253463 3254599 R prophage DNA injection protein complement(3253463..3254599) Escherichia coli O157:H7 str. TW14359 8217866 YP_003079152.1 CDS ECSP_3301 NC_013008.1 3254609 3255289 R prophage DNA injection protein complement(3254609..3255289) Escherichia coli O157:H7 str. TW14359 8217867 YP_003079153.1 CDS ECSP_3302 NC_013008.1 3255276 3255743 R hypothetical protein complement(3255276..3255743) Escherichia coli O157:H7 str. TW14359 8217868 YP_003079154.1 CDS ECSP_3303 NC_013008.1 3255743 3256312 R hypothetical protein complement(3255743..3256312) Escherichia coli O157:H7 str. TW14359 8217869 YP_003079155.1 CDS ECSP_3304 NC_013008.1 3256295 3256990 D hypothetical protein 3256295..3256990 Escherichia coli O157:H7 str. TW14359 8217870 YP_003079156.1 CDS ECSP_3305 NC_013008.1 3257170 3257313 R hypothetical protein complement(3257170..3257313) Escherichia coli O157:H7 str. TW14359 8217871 YP_003079157.1 CDS ECSP_3306 NC_013008.1 3257660 3259072 R hypothetical protein complement(3257660..3259072) Escherichia coli O157:H7 str. TW14359 8217872 YP_003079158.1 CDS ECSP_3307 NC_013008.1 3259259 3259435 R hypothetical protein complement(3259259..3259435) Escherichia coli O157:H7 str. TW14359 8217873 YP_003079159.1 CDS ECSP_3308 NC_013008.1 3259738 3260364 D resolvase 3259738..3260364 Escherichia coli O157:H7 str. TW14359 8217874 YP_003079160.1 CDS ECSP_3309 NC_013008.1 3260730 3260882 D hypothetical protein 3260730..3260882 Escherichia coli O157:H7 str. TW14359 8217875 YP_003079161.1 CDS lacY NC_013008.1 3260962 3262209 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(3260962..3262209) Escherichia coli O157:H7 str. TW14359 8217876 YP_003079162.1 CDS cscK NC_013008.1 3262281 3263195 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(3262281..3263195) Escherichia coli O157:H7 str. TW14359 8217877 YP_003079163.1 CDS cscA NC_013008.1 3263411 3264844 D sucrose 6-phosphate hydrolase 3263411..3264844 Escherichia coli O157:H7 str. TW14359 8217878 YP_003079164.1 CDS cscR NC_013008.1 3264852 3265847 R csc-specific repressor complement(3264852..3265847) Escherichia coli O157:H7 str. TW14359 8217879 YP_003079165.1 CDS dsdA NC_013008.1 3266326 3267654 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 3266326..3267654 Escherichia coli O157:H7 str. TW14359 8217881 YP_003079166.1 CDS emrY NC_013008.1 3267762 3269300 R multidrug efflux system complement(3267762..3269300) Escherichia coli O157:H7 str. TW14359 8217882 YP_003079167.1 CDS emrK NC_013008.1 3269300 3270463 R EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component complement(3269300..3270463) Escherichia coli O157:H7 str. TW14359 8217883 YP_003079168.1 CDS evgA NC_013008.1 3270879 3271493 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 3270879..3271493 Escherichia coli O157:H7 str. TW14359 8217884 YP_003079169.1 CDS evgS NC_013008.1 3271498 3275091 D hybrid sensory histidine kinase in two-component regulatory system with EvgA 3271498..3275091 Escherichia coli O157:H7 str. TW14359 8217885 YP_003079170.1 CDS yfdV NC_013008.1 3276362 3277306 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(3276362..3277306) Escherichia coli O157:H7 str. TW14359 8217887 YP_003079171.1 CDS oxc NC_013008.1 3277376 3279070 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(3277376..3279070) Escherichia coli O157:H7 str. TW14359 8217888 YP_003079172.1 CDS frc NC_013008.1 3279124 3280374 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(3279124..3280374) Escherichia coli O157:H7 str. TW14359 8217889 YP_003079173.1 CDS yfdX NC_013008.1 3280887 3281522 R hypothetical protein complement(3280887..3281522) Escherichia coli O157:H7 str. TW14359 8217890 YP_003079174.1 CDS ypdI NC_013008.1 3281818 3282093 D lipoprotein involved in colanic acid biosynthesis 3281818..3282093 Escherichia coli O157:H7 str. TW14359 8217891 YP_003079175.1 CDS yfdY NC_013008.1 3282170 3282412 R inner membrane protein complement(3282170..3282412) Escherichia coli O157:H7 str. TW14359 8217892 YP_003079176.1 CDS lpxP NC_013008.1 3282765 3283685 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 3282765..3283685 Escherichia coli O157:H7 str. TW14359 8217893 YP_003079177.1 CDS ECSP_3328 NC_013008.1 3283996 3284112 D hypothetical protein 3283996..3284112 Escherichia coli O157:H7 str. TW14359 8217894 YP_003079178.1 CDS yfdZ NC_013008.1 3284177 3285415 R aminotransferase complement(3284177..3285415) Escherichia coli O157:H7 str. TW14359 8217895 YP_003079179.1 CDS ypdA NC_013008.1 3285792 3287489 D sensory kinase in two-component system with YpdB 3285792..3287489 Escherichia coli O157:H7 str. TW14359 8217896 YP_003079180.1 CDS ypdB NC_013008.1 3287504 3288238 D response regulator in two-component system withYpdA 3287504..3288238 Escherichia coli O157:H7 str. TW14359 8217897 YP_003079181.1 CDS ypdC NC_013008.1 3288251 3289108 D DNA-binding protein 3288251..3289108 Escherichia coli O157:H7 str. TW14359 8217898 YP_003079182.1 CDS ECSP_3333 NC_013008.1 3289111 3291606 R fused PTS enzymes: Hpr component, enzyme I component, enzyme IIA component complement(3289111..3291606) Escherichia coli O157:H7 str. TW14359 8217899 YP_003079183.1 CDS ypdE NC_013008.1 3291631 3292668 R metalloprotein; exoaminopeptidase complement(3291631..3292668) Escherichia coli O157:H7 str. TW14359 8217900 YP_003079184.1 CDS ypdF NC_013008.1 3292668 3293753 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(3292668..3293753) Escherichia coli O157:H7 str. TW14359 8217901 YP_003079185.1 CDS ECSP_3336 NC_013008.1 3293768 3295015 R enzyme IIC component of PTS complement(3293768..3295015) Escherichia coli O157:H7 str. TW14359 8217902 YP_003079186.1 CDS ECSP_3337 NC_013008.1 3295037 3295363 R enzyme IIB component of PTS complement(3295037..3295363) Escherichia coli O157:H7 str. TW14359 8217903 YP_003079187.1 CDS glk NC_013008.1 3295582 3296547 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(3295582..3296547) Escherichia coli O157:H7 str. TW14359 8217904 YP_003079188.1 CDS yfeO NC_013008.1 3296751 3298007 D hypothetical protein 3296751..3298007 Escherichia coli O157:H7 str. TW14359 8217905 YP_003079189.1 CDS ypeC NC_013008.1 3298122 3298448 D hypothetical protein 3298122..3298448 Escherichia coli O157:H7 str. TW14359 8217906 YP_003079190.1 CDS mntH NC_013008.1 3298588 3299826 R manganese transport protein MntH complement(3298588..3299826) Escherichia coli O157:H7 str. TW14359 8217907 YP_003079191.1 CDS nupC NC_013008.1 3300162 3301364 D nucleoside (except guanosine) transporter 3300162..3301364 Escherichia coli O157:H7 str. TW14359 8217908 YP_003079192.1 CDS yfeA NC_013008.1 3301414 3303603 R diguanylate cyclase complement(3301414..3303603) Escherichia coli O157:H7 str. TW14359 8217909 YP_003079193.1 CDS yfeC NC_013008.1 3304237 3304581 D DNA-binding transcriptional regulator 3304237..3304581 Escherichia coli O157:H7 str. TW14359 8217912 YP_003079194.1 CDS yfeD NC_013008.1 3304583 3304975 D DNA-binding transcriptional regulator 3304583..3304975 Escherichia coli O157:H7 str. TW14359 8217913 YP_003079195.1 CDS ECSP_3348 NC_013008.1 3305015 3306223 R virulence protein complement(3305015..3306223) Escherichia coli O157:H7 str. TW14359 8217914 YP_003079196.1 CDS ECSP_3349 NC_013008.1 3306246 3306773 D transposase IS200 like protein 3306246..3306773 Escherichia coli O157:H7 str. TW14359 8217915 YP_003079197.1 CDS gltX NC_013008.1 3306774 3308189 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(3306774..3308189) Escherichia coli O157:H7 str. TW14359 8217916 YP_003079198.1 CDS ECSP_3355 NC_013008.1 3308965 3309306 D hypothetical protein 3308965..3309306 Escherichia coli O157:H7 str. TW14359 8217921 YP_003079199.1 CDS ECSP_3356 NC_013008.1 3309297 3310223 R LysR family transcriptional regulator complement(3309297..3310223) Escherichia coli O157:H7 str. TW14359 8217922 YP_003079200.1 CDS yfeH NC_013008.1 3310313 3311311 D inner membrane protein 3310313..3311311 Escherichia coli O157:H7 str. TW14359 8217923 YP_003079201.1 CDS ypeB NC_013008.1 3311308 3311526 R hypothetical protein complement(3311308..3311526) Escherichia coli O157:H7 str. TW14359 8217924 YP_003079202.1 CDS ligA NC_013008.1 3311528 3313543 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(3311528..3313543) Escherichia coli O157:H7 str. TW14359 8217925 YP_003079203.1 CDS zipA NC_013008.1 3313614 3314612 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(3313614..3314612) Escherichia coli O157:H7 str. TW14359 8217926 YP_003079204.1 CDS cysZ NC_013008.1 3314842 3315603 D role in sulfur assimilation; sulfate transport protein CysZ 3314842..3315603 Escherichia coli O157:H7 str. TW14359 8217927 YP_003079205.1 CDS cysK NC_013008.1 3315788 3316759 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 3315788..3316759 Escherichia coli O157:H7 str. TW14359 8217928 YP_003079206.1 CDS ptsH NC_013008.1 3317143 3317400 D PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 3317143..3317400 Escherichia coli O157:H7 str. TW14359 8217929 YP_003079207.1 CDS ptsI NC_013008.1 3317445 3319172 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 3317445..3319172 Escherichia coli O157:H7 str. TW14359 8217930 YP_003079208.1 CDS crr NC_013008.1 3319213 3319722 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 3319213..3319722 Escherichia coli O157:H7 str. TW14359 8217931 YP_003079209.1 CDS pdxK NC_013008.1 3319765 3320616 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(3319765..3320616) Escherichia coli O157:H7 str. TW14359 8217932 YP_003079210.1 CDS yfeK NC_013008.1 3320721 3321053 D hypothetical protein 3320721..3321053 Escherichia coli O157:H7 str. TW14359 8217933 YP_003079211.1 CDS cysM NC_013008.1 3321091 3322002 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(3321091..3322002) Escherichia coli O157:H7 str. TW14359 8217934 YP_003079212.1 CDS cysA NC_013008.1 3322136 3323233 R sulfate/thiosulfate transporter subunit complement(3322136..3323233) Escherichia coli O157:H7 str. TW14359 8217935 YP_003079213.1 CDS cysW NC_013008.1 3323223 3324098 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(3323223..3324098) Escherichia coli O157:H7 str. TW14359 8217936 YP_003079214.1 CDS cysU NC_013008.1 3324098 3324931 R sulfate/thiosulfate transporter subunit complement(3324098..3324931) Escherichia coli O157:H7 str. TW14359 8217937 YP_003079215.1 CDS cysP NC_013008.1 3324931 3325947 R thiosulfate transporter subunit complement(3324931..3325947) Escherichia coli O157:H7 str. TW14359 8217938 YP_003079216.1 CDS ucpA NC_013008.1 3326105 3326896 R short chain dehydrogenase complement(3326105..3326896) Escherichia coli O157:H7 str. TW14359 8217939 YP_003079217.1 CDS yfeT NC_013008.1 3327025 3327882 R DNA-binding transcriptional regulator complement(3327025..3327882) Escherichia coli O157:H7 str. TW14359 8217940 YP_003079218.1 CDS murQ NC_013008.1 3328046 3328942 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 3328046..3328942 Escherichia coli O157:H7 str. TW14359 8217941 YP_003079219.1 CDS murP NC_013008.1 3328946 3330370 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 3328946..3330370 Escherichia coli O157:H7 str. TW14359 8217942 YP_003079220.1 CDS yfeW NC_013008.1 3330375 3331679 D hypothetical protein 3330375..3331679 Escherichia coli O157:H7 str. TW14359 8217943 YP_003079221.1 CDS yfeX NC_013008.1 3331737 3332636 R hypothetical protein complement(3331737..3332636) Escherichia coli O157:H7 str. TW14359 8217944 YP_003079222.1 CDS yfeY NC_013008.1 3332732 3333307 R hypothetical protein complement(3332732..3333307) Escherichia coli O157:H7 str. TW14359 8217945 YP_003079223.1 CDS yfeZ NC_013008.1 3333368 3333817 R inner membrane protein complement(3333368..3333817) Escherichia coli O157:H7 str. TW14359 8217946 YP_003079224.1 CDS ypeA NC_013008.1 3333804 3334229 R acetyltransferase complement(3333804..3334229) Escherichia coli O157:H7 str. TW14359 8217947 YP_003079225.1 CDS amiA NC_013008.1 3334443 3335312 D N-acetylmuramoyl-l-alanine amidase I 3334443..3335312 Escherichia coli O157:H7 str. TW14359 8217948 YP_003079226.1 CDS hemF NC_013008.1 3335316 3336215 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 3335316..3336215 Escherichia coli O157:H7 str. TW14359 8217949 YP_003079227.1 CDS yfeG NC_013008.1 3336221 3337273 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(3336221..3337273) Escherichia coli O157:H7 str. TW14359 8217950 YP_003079228.1 CDS ECSP_3385 NC_013008.1 3337319 3337819 R carboxysome structural protein with role in ethanolamine utilization complement(3337319..3337819) Escherichia coli O157:H7 str. TW14359 8217951 YP_003079229.1 CDS ECSP_3386 NC_013008.1 3337832 3338491 R carboxysome structural protein with role in ethanolamine utilization complement(3337832..3338491) Escherichia coli O157:H7 str. TW14359 8217952 YP_003079230.1 CDS eutC NC_013008.1 3338501 3339388 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(3338501..3339388) Escherichia coli O157:H7 str. TW14359 8217953 YP_003079231.1 CDS eutB NC_013008.1 3339409 3340770 R ethanolamine ammonia-lyase, large subunit, heavy chain complement(3339409..3340770) Escherichia coli O157:H7 str. TW14359 8217954 YP_003079232.1 CDS eutA NC_013008.1 3340782 3342185 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(3340782..3342185) Escherichia coli O157:H7 str. TW14359 8217955 YP_003079233.1 CDS eutH NC_013008.1 3342182 3343408 R inner membrane protein complement(3342182..3343408) Escherichia coli O157:H7 str. TW14359 8217956 YP_003079234.1 CDS eutG NC_013008.1 3343508 3344695 R alcohol dehydrogenase in ethanolamine utilization complement(3343508..3344695) Escherichia coli O157:H7 str. TW14359 8217957 YP_003079235.1 CDS eutJ NC_013008.1 3344685 3345521 R chaperonin, ethanolamine utilization protein complement(3344685..3345521) Escherichia coli O157:H7 str. TW14359 8217958 YP_003079236.1 CDS eutE NC_013008.1 3345532 3346935 R aldehyde dehydrogenase, ethanolamine utilization protein complement(3345532..3346935) Escherichia coli O157:H7 str. TW14359 8217959 YP_003079237.1 CDS cchB NC_013008.1 3346947 3347234 R carboxysome structural protein, ethanolamine utilization protein complement(3346947..3347234) Escherichia coli O157:H7 str. TW14359 8217960 YP_003079238.1 CDS cchA NC_013008.1 3347341 3347634 R carboxysome structural protein, ethanolamine utilization protein complement(3347341..3347634) Escherichia coli O157:H7 str. TW14359 8217961 YP_003079239.1 CDS eutD NC_013008.1 3347673 3348689 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(3347673..3348689) Escherichia coli O157:H7 str. TW14359 8217962 YP_003079240.1 CDS ECSP_3397 NC_013008.1 3348686 3349417 R cobalamin adenosyltransferase in ethanolamine utilization complement(3348686..3349417) Escherichia coli O157:H7 str. TW14359 8217963 YP_003079241.1 CDS ECSP_3398 NC_013008.1 3349414 3350115 R hypothetical protein complement(3349414..3350115) Escherichia coli O157:H7 str. TW14359 8217964 YP_003079242.1 CDS ECSP_3399 NC_013008.1 3350090 3350569 R hypothetical protein complement(3350090..3350569) Escherichia coli O157:H7 str. TW14359 8217965 YP_003079243.1 CDS ECSP_3400 NC_013008.1 3350582 3350917 R carboxysome structural protein with role in ethanol utilization complement(3350582..3350917) Escherichia coli O157:H7 str. TW14359 8217966 YP_003079244.1 CDS maeB NC_013008.1 3351210 3353489 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(3351210..3353489) Escherichia coli O157:H7 str. TW14359 8217967 YP_003079245.1 CDS talA NC_013008.1 3353778 3354728 D transaldolase A 3353778..3354728 Escherichia coli O157:H7 str. TW14359 8217968 YP_003079246.1 CDS tktB NC_013008.1 3354748 3356751 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3354748..3356751 Escherichia coli O157:H7 str. TW14359 8217969 YP_003079247.1 CDS ypfG NC_013008.1 3356846 3357889 R hypothetical protein complement(3356846..3357889) Escherichia coli O157:H7 str. TW14359 8217970 YP_003079248.1 CDS nudK NC_013008.1 3358015 3358590 R GDP-mannose pyrophosphatase complement(3358015..3358590) Escherichia coli O157:H7 str. TW14359 8217971 YP_003079249.1 CDS aegA NC_013008.1 3358658 3360637 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3358658..3360637) Escherichia coli O157:H7 str. TW14359 8217972 YP_003079250.1 CDS narQ NC_013008.1 3360843 3362543 D nitrate/nitrite sensor protein NarQ 3360843..3362543 Escherichia coli O157:H7 str. TW14359 8217973 YP_003079251.1 CDS acrD NC_013008.1 3362707 3365820 D aminoglycoside/multidrug efflux system 3362707..3365820 Escherichia coli O157:H7 str. TW14359 8217974 YP_003079252.1 CDS yffB NC_013008.1 3366359 3366715 D hypothetical protein 3366359..3366715 Escherichia coli O157:H7 str. TW14359 8217975 YP_003079253.1 CDS dapE NC_013008.1 3366719 3367846 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 3366719..3367846 Escherichia coli O157:H7 str. TW14359 8217976 YP_003079254.1 CDS ypfN NC_013008.1 3367874 3368074 D hypothetical protein 3367874..3368074 Escherichia coli O157:H7 str. TW14359 8217977 YP_003079255.1 CDS ypfH NC_013008.1 3368155 3368853 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH complement(3368155..3368853) Escherichia coli O157:H7 str. TW14359 8217978 YP_003079256.1 CDS ypfI NC_013008.1 3368927 3370942 R hydrolase complement(3368927..3370942) Escherichia coli O157:H7 str. TW14359 8217979 YP_003079257.1 CDS ypfJ NC_013008.1 3370957 3371820 R hypothetical protein complement(3370957..3371820) Escherichia coli O157:H7 str. TW14359 8217980 YP_003079258.1 CDS purC NC_013008.1 3371988 3372701 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(3371988..3372701) Escherichia coli O157:H7 str. TW14359 8217981 YP_003079259.1 CDS nlpB NC_013008.1 3372914 3373948 R lipoprotein complement(3372914..3373948) Escherichia coli O157:H7 str. TW14359 8217982 YP_003079260.1 CDS dapA NC_013008.1 3373965 3374843 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(3373965..3374843) Escherichia coli O157:H7 str. TW14359 8217983 YP_003079261.1 CDS gcvR NC_013008.1 3374989 3375561 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 3374989..3375561 Escherichia coli O157:H7 str. TW14359 8217984 YP_003079262.1 CDS bcp NC_013008.1 3375561 3376031 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 3375561..3376031 Escherichia coli O157:H7 str. TW14359 8217985 YP_003079263.1 CDS hyfA NC_013008.1 3376284 3376901 D hydrogenase 4, 4Fe-4S subunit 3376284..3376901 Escherichia coli O157:H7 str. TW14359 8217986 YP_003079264.1 CDS hyfB NC_013008.1 3376901 3378919 D hydrogenase 4 subunit B 3376901..3378919 Escherichia coli O157:H7 str. TW14359 8217987 YP_003079265.1 CDS hyfC NC_013008.1 3378930 3379877 D hydrogenase 4, membrane subunit 3378930..3379877 Escherichia coli O157:H7 str. TW14359 8217988 YP_003079266.1 CDS hyfD NC_013008.1 3379894 3381333 D hydrogenase 4 subunit D 3379894..3381333 Escherichia coli O157:H7 str. TW14359 8217989 YP_003079267.1 CDS hyfE NC_013008.1 3381345 3381995 D interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 3381345..3381995 Escherichia coli O157:H7 str. TW14359 8217990 YP_003079268.1 CDS hyfF NC_013008.1 3382000 3383580 D hydrogenase 4 subunit F 3382000..3383580 Escherichia coli O157:H7 str. TW14359 8217991 YP_003079269.1 CDS hyfG NC_013008.1 3383570 3385285 D hydrogenase 4 subunit 3383570..3385285 Escherichia coli O157:H7 str. TW14359 8217992 YP_003079270.1 CDS hyfH NC_013008.1 3385295 3385840 D probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 3385295..3385840 Escherichia coli O157:H7 str. TW14359 8217993 YP_003079271.1 CDS hyfI NC_013008.1 3385837 3386595 D hydrogenase 4, Fe-S subunit 3385837..3386595 Escherichia coli O157:H7 str. TW14359 8217994 YP_003079272.1 CDS hyfJ NC_013008.1 3386588 3387001 D processing element hydrogenase 4 3386588..3387001 Escherichia coli O157:H7 str. TW14359 8217995 YP_003079273.1 CDS hyfR NC_013008.1 3387031 3389043 D DNA-binding transcriptional activator, formate sensing 3387031..3389043 Escherichia coli O157:H7 str. TW14359 8217996 YP_003079274.1 CDS focB NC_013008.1 3389065 3389913 D inner membrane protein presumed to act as a formate transporter; member of the hyf operon; formate transporter 3389065..3389913 Escherichia coli O157:H7 str. TW14359 8217997 YP_003079275.1 CDS yfgO NC_013008.1 3389951 3391012 R inner membrane protein complement(3389951..3391012) Escherichia coli O157:H7 str. TW14359 8217998 YP_003079276.1 CDS yfgC NC_013008.1 3391225 3392688 D peptidase 3391225..3392688 Escherichia coli O157:H7 str. TW14359 8217999 YP_003079277.1 CDS yfgD NC_013008.1 3392709 3393068 D oxidoreductase 3392709..3393068 Escherichia coli O157:H7 str. TW14359 8218000 YP_003079278.1 CDS hda NC_013008.1 3393206 3393952 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(3393206..3393952) Escherichia coli O157:H7 str. TW14359 8218001 YP_003079279.1 CDS uraA NC_013008.1 3394002 3395291 R uracil transporter complement(3394002..3395291) Escherichia coli O157:H7 str. TW14359 8218002 YP_003079280.1 CDS upp NC_013008.1 3395377 3396003 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(3395377..3396003) Escherichia coli O157:H7 str. TW14359 8218003 YP_003079281.1 CDS purM NC_013008.1 3396328 3397365 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 3396328..3397365 Escherichia coli O157:H7 str. TW14359 8218004 YP_003079282.1 CDS purN NC_013008.1 3397365 3398003 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3397365..3398003 Escherichia coli O157:H7 str. TW14359 8218005 YP_003079283.1 CDS ppk NC_013008.1 3398174 3400240 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3398174..3400240 Escherichia coli O157:H7 str. TW14359 8218006 YP_003079284.1 CDS ppx NC_013008.1 3400245 3401786 D exopolyphosphatase 3400245..3401786 Escherichia coli O157:H7 str. TW14359 8218007 YP_003079285.1 CDS yfgF NC_013008.1 3401825 3404068 R inner membrane protein complement(3401825..3404068) Escherichia coli O157:H7 str. TW14359 8218008 YP_003079286.1 CDS ECSP_3443 NC_013008.1 3404250 3404402 R hypothetical protein complement(3404250..3404402) Escherichia coli O157:H7 str. TW14359 8218009 YP_003079287.1 CDS yfgG NC_013008.1 3404420 3404611 D hypothetical protein 3404420..3404611 Escherichia coli O157:H7 str. TW14359 8218010 YP_003079288.1 CDS yfgH NC_013008.1 3404922 3405440 D outer membrane lipoprotein 3404922..3405440 Escherichia coli O157:H7 str. TW14359 8218011 YP_003079289.1 CDS yfgI NC_013008.1 3405456 3405995 D hypothetical protein 3405456..3405995 Escherichia coli O157:H7 str. TW14359 8218012 YP_003079290.1 CDS guaA NC_013008.1 3406088 3407665 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(3406088..3407665) Escherichia coli O157:H7 str. TW14359 8218013 YP_003079291.1 CDS guaB NC_013008.1 3407734 3409200 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(3407734..3409200) Escherichia coli O157:H7 str. TW14359 8218014 YP_003079292.1 CDS xseA NC_013008.1 3409362 3410732 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3409362..3410732 Escherichia coli O157:H7 str. TW14359 8218015 YP_003079293.1 CDS yfgJ NC_013008.1 3410729 3410944 R hypothetical protein complement(3410729..3410944) Escherichia coli O157:H7 str. TW14359 8218016 YP_003079294.1 CDS engA NC_013008.1 3411013 3412485 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(3411013..3412485) Escherichia coli O157:H7 str. TW14359 8218017 YP_003079295.1 CDS yfgL NC_013008.1 3412603 3413781 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(3412603..3413781) Escherichia coli O157:H7 str. TW14359 8218018 YP_003079296.1 CDS yfgM NC_013008.1 3413792 3414412 R hypothetical protein complement(3413792..3414412) Escherichia coli O157:H7 str. TW14359 8218019 YP_003079297.1 CDS hisS NC_013008.1 3414430 3415704 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(3414430..3415704) Escherichia coli O157:H7 str. TW14359 8218020 YP_003079298.1 CDS ispG NC_013008.1 3415815 3416933 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(3415815..3416933) Escherichia coli O157:H7 str. TW14359 8218021 YP_003079299.1 CDS yfgA NC_013008.1 3416960 3417973 R cytoskeletal protein RodZ complement(3416960..3417973) Escherichia coli O157:H7 str. TW14359 8218022 YP_003079300.1 CDS yfgB NC_013008.1 3418258 3419412 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(3418258..3419412) Escherichia coli O157:H7 str. TW14359 8218023 YP_003079301.1 CDS ndk NC_013008.1 3419562 3419993 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(3419562..3419993) Escherichia coli O157:H7 str. TW14359 8218024 YP_003079302.1 CDS ECSP_3459 NC_013008.1 3420134 3420712 R hypothetical protein complement(3420134..3420712) Escherichia coli O157:H7 str. TW14359 8218025 YP_003079303.1 CDS ECSP_3460 NC_013008.1 3420988 3421809 R dimethyl sulfoxide reductase subunit C complement(3420988..3421809) Escherichia coli O157:H7 str. TW14359 8218026 YP_003079304.1 CDS ECSP_3461 NC_013008.1 3421802 3422431 R dimethyl sulfoxide reductase subunit B complement(3421802..3422431) Escherichia coli O157:H7 str. TW14359 8218027 YP_003079305.1 CDS ECSP_3462 NC_013008.1 3422428 3424809 R dimethyl sulfoxide reductase subunit A complement(3422428..3424809) Escherichia coli O157:H7 str. TW14359 8218028 YP_003079306.1 CDS pbpC NC_013008.1 3424973 3427285 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(3424973..3427285) Escherichia coli O157:H7 str. TW14359 8218029 YP_003079307.1 CDS yfhM NC_013008.1 3427286 3432247 R hypothetical protein complement(3427286..3432247) Escherichia coli O157:H7 str. TW14359 8218030 YP_003079308.1 CDS sseA NC_013008.1 3432454 3433299 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 3432454..3433299 Escherichia coli O157:H7 str. TW14359 8218031 YP_003079309.1 CDS sseB NC_013008.1 3433799 3434587 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(3433799..3434587) Escherichia coli O157:H7 str. TW14359 8218032 YP_003079310.1 CDS pepB NC_013008.1 3434718 3436001 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase complement(3434718..3436001) Escherichia coli O157:H7 str. TW14359 8218033 YP_003079311.1 CDS iscX NC_013008.1 3436179 3436379 R hypothetical protein complement(3436179..3436379) Escherichia coli O157:H7 str. TW14359 8218034 YP_003079312.1 CDS fdx NC_013008.1 3436391 3436726 R [2Fe-2S] ferredoxin complement(3436391..3436726) Escherichia coli O157:H7 str. TW14359 8218035 YP_003079313.1 CDS hscA NC_013008.1 3436728 3438578 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(3436728..3438578) Escherichia coli O157:H7 str. TW14359 8218036 YP_003079314.1 CDS hscB NC_013008.1 3438595 3439110 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(3438595..3439110) Escherichia coli O157:H7 str. TW14359 8218037 YP_003079315.1 CDS iscA NC_013008.1 3439206 3439529 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(3439206..3439529) Escherichia coli O157:H7 str. TW14359 8218038 YP_003079316.1 CDS iscU NC_013008.1 3439546 3439932 R scaffold protein complement(3439546..3439932) Escherichia coli O157:H7 str. TW14359 8218039 YP_003079317.1 CDS iscS NC_013008.1 3439960 3441174 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(3439960..3441174) Escherichia coli O157:H7 str. TW14359 8218040 YP_003079318.1 CDS iscR NC_013008.1 3441286 3441774 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(3441286..3441774) Escherichia coli O157:H7 str. TW14359 8218041 YP_003079319.1 CDS trmJ NC_013008.1 3442075 3442812 R tRNA Cm32/Um32 methyltransferase complement(3442075..3442812) Escherichia coli O157:H7 str. TW14359 8218042 YP_003079320.1 CDS suhB NC_013008.1 3442931 3443734 D inositol monophosphatase 3442931..3443734 Escherichia coli O157:H7 str. TW14359 8218043 YP_003079321.1 CDS yfhR NC_013008.1 3443879 3444733 D peptidase 3443879..3444733 Escherichia coli O157:H7 str. TW14359 8218044 YP_003079322.1 CDS csiE NC_013008.1 3444924 3446204 D stationary phase inducible protein CsiE 3444924..3446204 Escherichia coli O157:H7 str. TW14359 8218045 YP_003079323.1 CDS hcaT NC_013008.1 3446196 3447335 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(3446196..3447335) Escherichia coli O157:H7 str. TW14359 8218046 YP_003079324.1 CDS hcaR NC_013008.1 3447495 3448385 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR complement(3447495..3448385) Escherichia coli O157:H7 str. TW14359 8218047 YP_003079325.1 CDS hcaE NC_013008.1 3448521 3449882 D 3-phenylpropionate dioxygenase large subunit alpha 3448521..3449882 Escherichia coli O157:H7 str. TW14359 8218048 YP_003079326.1 CDS hcaF NC_013008.1 3449879 3450397 D 3-phenylpropionate dioxygenase subunit beta 3449879..3450397 Escherichia coli O157:H7 str. TW14359 8218049 YP_003079327.1 CDS hcaC NC_013008.1 3450397 3450717 D 3-phenylpropionate dioxygenase ferredoxin subunit 3450397..3450717 Escherichia coli O157:H7 str. TW14359 8218050 YP_003079328.1 CDS hcaB NC_013008.1 3450714 3451526 D Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 3450714..3451526 Escherichia coli O157:H7 str. TW14359 8218051 YP_003079329.1 CDS hcaD NC_013008.1 3451536 3452738 D phenylpropionate dioxygenase ferredoxin reductase subunit 3451536..3452738 Escherichia coli O157:H7 str. TW14359 8218052 YP_003079330.1 CDS yphA NC_013008.1 3452835 3453257 D inner membrane protein 3452835..3453257 Escherichia coli O157:H7 str. TW14359 8218053 YP_003079331.1 CDS yphB NC_013008.1 3453305 3454177 R hypothetical protein complement(3453305..3454177) Escherichia coli O157:H7 str. TW14359 8218054 YP_003079332.1 CDS yphD NC_013008.1 3455316 3456314 R sugar ABC transporter membrane protein complement(3455316..3456314) Escherichia coli O157:H7 str. TW14359 8218056 YP_003079333.1 CDS yphE NC_013008.1 3456339 3457850 R sugar ABC transporter ATP-binding protein complement(3456339..3457850) Escherichia coli O157:H7 str. TW14359 8218057 YP_003079334.1 CDS yphF NC_013008.1 3457873 3458856 R sugar ABC transporter periplasmic-binding protein complement(3457873..3458856) Escherichia coli O157:H7 str. TW14359 8218058 YP_003079335.1 CDS yphG NC_013008.1 3458953 3462234 R hypothetical protein complement(3458953..3462234) Escherichia coli O157:H7 str. TW14359 8218059 YP_003079336.1 CDS yphH NC_013008.1 3462352 3463545 D DNA-binding transcriptional regulator 3462352..3463545 Escherichia coli O157:H7 str. TW14359 8218060 YP_003079337.1 CDS glyA NC_013008.1 3463608 3464861 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(3463608..3464861) Escherichia coli O157:H7 str. TW14359 8218061 YP_003079338.1 CDS hmp NC_013008.1 3465189 3466379 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 3465189..3466379 Escherichia coli O157:H7 str. TW14359 8218062 YP_003079339.1 CDS glnB NC_013008.1 3466424 3466762 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(3466424..3466762) Escherichia coli O157:H7 str. TW14359 8218063 YP_003079340.1 CDS qseF NC_013008.1 3466823 3468157 R DNA-binding response regulator in two-component regulatory system with QseE complement(3466823..3468157) Escherichia coli O157:H7 str. TW14359 8218064 YP_003079341.1 CDS yfhG NC_013008.1 3468147 3468860 R hypothetical protein complement(3468147..3468860) Escherichia coli O157:H7 str. TW14359 8218065 YP_003079342.1 CDS qseE NC_013008.1 3469025 3470452 R sensory histidine kinase in two-component regulatory system with QseF complement(3469025..3470452) Escherichia coli O157:H7 str. TW14359 8218066 YP_003079343.1 CDS purL NC_013008.1 3471028 3474915 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(3471028..3474915) Escherichia coli O157:H7 str. TW14359 8218067 YP_003079344.1 CDS yfhD NC_013008.1 3475172 3476728 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 3475172..3476728 Escherichia coli O157:H7 str. TW14359 8218068 YP_003079345.1 CDS tadA NC_013008.1 3476725 3477228 R tRNA-specific adenosine deaminase complement(3476725..3477228) Escherichia coli O157:H7 str. TW14359 8218069 YP_003079346.1 CDS yfhB NC_013008.1 3477286 3477921 R hypothetical protein complement(3477286..3477921) Escherichia coli O157:H7 str. TW14359 8218070 YP_003079347.1 CDS yfhH NC_013008.1 3478130 3478978 D DNA-binding transcriptional regulator 3478130..3478978 Escherichia coli O157:H7 str. TW14359 8218071 YP_003079348.1 CDS yfhL NC_013008.1 3479034 3479294 D 4Fe-4S cluster-containing protein 3479034..3479294 Escherichia coli O157:H7 str. TW14359 8218072 YP_003079349.1 CDS ECSP_3507 NC_013008.1 3479565 3479717 R hypothetical protein complement(3479565..3479717) Escherichia coli O157:H7 str. TW14359 8218073 YP_003079350.1 CDS acpS NC_013008.1 3479990 3480370 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(3479990..3480370) Escherichia coli O157:H7 str. TW14359 8218074 YP_003079351.1 CDS pdxJ NC_013008.1 3480370 3481101 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(3480370..3481101) Escherichia coli O157:H7 str. TW14359 8218075 YP_003079352.1 CDS recO NC_013008.1 3481113 3481841 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(3481113..3481841) Escherichia coli O157:H7 str. TW14359 8218076 YP_003079353.1 CDS era NC_013008.1 3481853 3482758 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(3481853..3482758) Escherichia coli O157:H7 str. TW14359 8218077 YP_003079354.1 CDS rnc NC_013008.1 3482755 3483435 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(3482755..3483435) Escherichia coli O157:H7 str. TW14359 8218078 YP_003079355.1 CDS ECSP_3513 NC_013008.1 3483493 3483657 D hypothetical protein 3483493..3483657 Escherichia coli O157:H7 str. TW14359 8218079 YP_003079356.1 CDS lepB NC_013008.1 3483708 3484682 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(3483708..3484682) Escherichia coli O157:H7 str. TW14359 8218080 YP_003079357.1 CDS lepA NC_013008.1 3484698 3486497 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(3484698..3486497) Escherichia coli O157:H7 str. TW14359 8218081 YP_003079358.1 CDS rseC NC_013008.1 3486695 3487174 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(3486695..3487174) Escherichia coli O157:H7 str. TW14359 8218082 YP_003079359.1 CDS rseB NC_013008.1 3487171 3488127 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(3487171..3488127) Escherichia coli O157:H7 str. TW14359 8218083 YP_003079360.1 CDS rseA NC_013008.1 3488127 3488765 R anti-RNA polymerase sigma factor SigE complement(3488127..3488765) Escherichia coli O157:H7 str. TW14359 8218084 YP_003079361.1 CDS rpoE NC_013008.1 3488798 3489373 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(3488798..3489373) Escherichia coli O157:H7 str. TW14359 8218085 YP_003079362.1 CDS nadB NC_013008.1 3489781 3491403 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 3489781..3491403 Escherichia coli O157:H7 str. TW14359 8218086 YP_003079363.1 CDS yfiC NC_013008.1 3491388 3492125 R S-adenosyl-L-methionine-dependent methyltransferase complement(3491388..3492125) Escherichia coli O157:H7 str. TW14359 8218087 YP_003079364.1 CDS srmB NC_013008.1 3492257 3493591 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3492257..3493591 Escherichia coli O157:H7 str. TW14359 8218088 YP_003079365.1 CDS yfiE NC_013008.1 3493624 3494505 R DNA-binding transcriptional regulator complement(3493624..3494505) Escherichia coli O157:H7 str. TW14359 8218089 YP_003079366.1 CDS yfiK NC_013008.1 3494608 3495195 D neutral amino-acid efflux protein 3494608..3495195 Escherichia coli O157:H7 str. TW14359 8218090 YP_003079367.1 CDS yfiD NC_013008.1 3495251 3495634 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(3495251..3495634) Escherichia coli O157:H7 str. TW14359 8218091 YP_003079368.1 CDS ung NC_013008.1 3495939 3496628 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3495939..3496628 Escherichia coli O157:H7 str. TW14359 8218092 YP_003079369.1 CDS yfiF NC_013008.1 3496676 3497713 R methyltransferase complement(3496676..3497713) Escherichia coli O157:H7 str. TW14359 8218093 YP_003079370.1 CDS ECSP_3528 NC_013008.1 3497703 3497906 R hypothetical protein complement(3497703..3497906) Escherichia coli O157:H7 str. TW14359 8218094 YP_003079371.1 CDS trxC NC_013008.1 3497920 3498339 D thioredoxin 2 3497920..3498339 Escherichia coli O157:H7 str. TW14359 8218095 YP_003079372.1 CDS yfiP NC_013008.1 3498408 3499106 D hypothetical protein 3498408..3499106 Escherichia coli O157:H7 str. TW14359 8218096 YP_003079373.1 CDS yfiQ NC_013008.1 3499138 3501798 D acyl-CoA synthetase: NAD(P)-binding subunit and ATP-binding subunit 3499138..3501798 Escherichia coli O157:H7 str. TW14359 8218097 YP_003079374.1 CDS pssA NC_013008.1 3501912 3503267 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3501912..3503267 Escherichia coli O157:H7 str. TW14359 8218098 YP_003079375.1 CDS yfiM NC_013008.1 3503313 3503636 D hypothetical protein 3503313..3503636 Escherichia coli O157:H7 str. TW14359 8218099 YP_003079376.1 CDS kgtP NC_013008.1 3503633 3504931 R alpha-ketoglutarate transporter complement(3503633..3504931) Escherichia coli O157:H7 str. TW14359 8218100 YP_003079377.1 CDS clpB NC_013008.1 3510705 3513278 R protein disaggregation chaperone complement(3510705..3513278) Escherichia coli O157:H7 str. TW14359 8218105 YP_003079378.1 CDS yfiH NC_013008.1 3513408 3514139 R hypothetical protein complement(3513408..3514139) Escherichia coli O157:H7 str. TW14359 8218106 YP_003079379.1 CDS rluD NC_013008.1 3514136 3515116 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(3514136..3515116) Escherichia coli O157:H7 str. TW14359 8218107 YP_003079380.1 CDS yfiO NC_013008.1 3515251 3515988 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3515251..3515988 Escherichia coli O157:H7 str. TW14359 8218108 YP_003079381.1 CDS raiA NC_013008.1 3516259 3516600 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3516259..3516600 Escherichia coli O157:H7 str. TW14359 8218109 YP_003079382.1 CDS pheA NC_013008.1 3516850 3518010 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3516850..3518010 Escherichia coli O157:H7 str. TW14359 8218110 YP_003079383.1 CDS tyrA NC_013008.1 3518053 3519174 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(3518053..3519174) Escherichia coli O157:H7 str. TW14359 8218111 YP_003079384.1 CDS aroF NC_013008.1 3519185 3520255 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3519185..3520255) Escherichia coli O157:H7 str. TW14359 8218112 YP_003079385.1 CDS yfiL NC_013008.1 3520465 3520830 D hypothetical protein 3520465..3520830 Escherichia coli O157:H7 str. TW14359 8218113 YP_003079386.1 CDS yfiR NC_013008.1 3520980 3521498 D hypothetical protein 3520980..3521498 Escherichia coli O157:H7 str. TW14359 8218114 YP_003079387.1 CDS yfiN NC_013008.1 3521488 3522714 D hypothetical protein 3521488..3522714 Escherichia coli O157:H7 str. TW14359 8218115 YP_003079388.1 CDS yfiB NC_013008.1 3522730 3523212 D outer membrane lipoprotein 3522730..3523212 Escherichia coli O157:H7 str. TW14359 8218116 YP_003079389.1 CDS rplS NC_013008.1 3523289 3523636 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(3523289..3523636) Escherichia coli O157:H7 str. TW14359 8218117 YP_003079390.1 CDS trmD NC_013008.1 3523678 3524445 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(3523678..3524445) Escherichia coli O157:H7 str. TW14359 8218118 YP_003079391.1 CDS rimM NC_013008.1 3524476 3525024 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(3524476..3525024) Escherichia coli O157:H7 str. TW14359 8218119 YP_003079392.1 CDS rpsP NC_013008.1 3525043 3525291 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(3525043..3525291) Escherichia coli O157:H7 str. TW14359 8218120 YP_003079393.1 CDS ffh NC_013008.1 3525428 3526789 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(3525428..3526789) Escherichia coli O157:H7 str. TW14359 8218121 YP_003079394.1 CDS ypjD NC_013008.1 3526881 3527747 D inner membrane protein 3526881..3527747 Escherichia coli O157:H7 str. TW14359 8218122 YP_003079395.1 CDS yfjD NC_013008.1 3527769 3528548 D inner membrane protein 3527769..3528548 Escherichia coli O157:H7 str. TW14359 8218123 YP_003079396.1 CDS grpE NC_013008.1 3529109 3529702 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(3529109..3529702) Escherichia coli O157:H7 str. TW14359 8218124 YP_003079397.1 CDS ppnK NC_013008.1 3529825 3530703 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3529825..3530703 Escherichia coli O157:H7 str. TW14359 8218125 YP_003079398.1 CDS recN NC_013008.1 3530789 3532450 D recombination and repair protein 3530789..3532450 Escherichia coli O157:H7 str. TW14359 8218126 YP_003079399.1 CDS smpA NC_013008.1 3532599 3532940 D hypothetical protein 3532599..3532940 Escherichia coli O157:H7 str. TW14359 8218127 YP_003079400.1 CDS yfjF NC_013008.1 3533002 3533292 R hypothetical protein complement(3533002..3533292) Escherichia coli O157:H7 str. TW14359 8218128 YP_003079401.1 CDS yfjG NC_013008.1 3533282 3533758 R hypothetical protein complement(3533282..3533758) Escherichia coli O157:H7 str. TW14359 8218129 YP_003079402.1 CDS smpB NC_013008.1 3533890 3534372 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3533890..3534372 Escherichia coli O157:H7 str. TW14359 8218130 YP_003079403.1 CDS ECSP_3565 NC_013008.1 3535218 3535466 D hypothetical protein 3535218..3535466 Escherichia coli O157:H7 str. TW14359 8218131 YP_003079404.1 CDS ECSP_3566 NC_013008.1 3535587 3535790 D hypothetical protein 3535587..3535790 Escherichia coli O157:H7 str. TW14359 8218132 YP_003079405.1 CDS espM2 NC_013008.1 3535968 3536552 R non-LEE-encoded type III effector complement(3535968..3536552) Escherichia coli O157:H7 str. TW14359 8218133 YP_003079406.1 CDS ECSP_3568 NC_013008.1 3536741 3537391 D non-LEE-encoded type III effector 3536741..3537391 Escherichia coli O157:H7 str. TW14359 8218134 YP_003079407.1 CDS espW NC_013008.1 3537470 3538528 D non-LEE-encoded type III effector 3537470..3538528 Escherichia coli O157:H7 str. TW14359 8218135 YP_003079408.1 CDS ECSP_3570 NC_013008.1 3538658 3539065 R hypothetical protein complement(3538658..3539065) Escherichia coli O157:H7 str. TW14359 8218136 YP_003079409.1 CDS ECSP_3571 NC_013008.1 3539241 3539510 R hypothetical protein complement(3539241..3539510) Escherichia coli O157:H7 str. TW14359 8218137 YP_003079410.1 CDS ECSP_3572 NC_013008.1 3539728 3540054 D transposase 3539728..3540054 Escherichia coli O157:H7 str. TW14359 8218138 YP_003079411.1 CDS ECSP_3573 NC_013008.1 3540051 3540941 D transposase 3540051..3540941 Escherichia coli O157:H7 str. TW14359 8218139 YP_003079412.1 CDS ECSP_3574 NC_013008.1 3540748 3541392 R hypothetical protein complement(3540748..3541392) Escherichia coli O157:H7 str. TW14359 8218140 YP_003079413.1 CDS ECSP_3575 NC_013008.1 3541442 3541789 R hypothetical protein complement(3541442..3541789) Escherichia coli O157:H7 str. TW14359 8218141 YP_003079414.1 CDS ECSP_3576 NC_013008.1 3541786 3542187 R hypothetical protein complement(3541786..3542187) Escherichia coli O157:H7 str. TW14359 8218142 YP_003079415.1 CDS ECSP_3577 NC_013008.1 3542242 3542472 R phage-related lysozyme complement(3542242..3542472) Escherichia coli O157:H7 str. TW14359 8218143 YP_003079416.1 CDS ECSP_3578 NC_013008.1 3542523 3542867 R hypothetical protein complement(3542523..3542867) Escherichia coli O157:H7 str. TW14359 8218144 YP_003079417.1 CDS ECSP_3579 NC_013008.1 3542872 3543186 R holin protein of prophage CP-933U complement(3542872..3543186) Escherichia coli O157:H7 str. TW14359 8218145 YP_003079418.1 CDS ECSP_3580 NC_013008.1 3543237 3545090 R hypothetical protein complement(3543237..3545090) Escherichia coli O157:H7 str. TW14359 8218146 YP_003079419.1 CDS ECSP_3581 NC_013008.1 3545498 3545608 R hypothetical protein complement(3545498..3545608) Escherichia coli O157:H7 str. TW14359 8218147 YP_003079420.1 CDS ECSP_3582 NC_013008.1 3545751 3546467 R hypothetical protein complement(3545751..3546467) Escherichia coli O157:H7 str. TW14359 8218148 YP_003079421.1 CDS ECSP_3583 NC_013008.1 3546747 3547370 R antiterminator of prophage CP-933Y complement(3546747..3547370) Escherichia coli O157:H7 str. TW14359 8218149 YP_003079422.1 CDS ECSP_3584 NC_013008.1 3547367 3548032 R serine/threonine protein phosphatase complement(3547367..3548032) Escherichia coli O157:H7 str. TW14359 8218150 YP_003079423.1 CDS ECSP_3585 NC_013008.1 3548029 3548640 R hypothetical protein complement(3548029..3548640) Escherichia coli O157:H7 str. TW14359 8218151 YP_003079424.1 CDS ECSP_3586 NC_013008.1 3548615 3549181 R hypothetical protein complement(3548615..3549181) Escherichia coli O157:H7 str. TW14359 8218152 YP_003079425.1 CDS ECSP_3587 NC_013008.1 3549547 3550302 D transposase, IS30 3549547..3550302 Escherichia coli O157:H7 str. TW14359 8218153 YP_003079426.1 CDS ECSP_3588 NC_013008.1 3550362 3550640 D hypothetical protein 3550362..3550640 Escherichia coli O157:H7 str. TW14359 8218154 YP_003079427.1 CDS ECSP_3589 NC_013008.1 3550716 3551924 R hypothetical protein complement(3550716..3551924) Escherichia coli O157:H7 str. TW14359 8218155 YP_003079428.1 CDS ECSP_3590 NC_013008.1 3552320 3552733 R hypothetical protein complement(3552320..3552733) Escherichia coli O157:H7 str. TW14359 8218156 YP_003079429.1 CDS ECSP_3591 NC_013008.1 3552831 3553052 R hypothetical protein complement(3552831..3553052) Escherichia coli O157:H7 str. TW14359 8218157 YP_003079430.1 CDS ECSP_3592 NC_013008.1 3553230 3554861 R hypothetical protein complement(3553230..3554861) Escherichia coli O157:H7 str. TW14359 8218158 YP_003079431.1 CDS ECSP_3593 NC_013008.1 3554858 3556171 R hypothetical protein complement(3554858..3556171) Escherichia coli O157:H7 str. TW14359 8218159 YP_003079432.1 CDS ECSP_3594 NC_013008.1 3556173 3557378 R hypothetical protein complement(3556173..3557378) Escherichia coli O157:H7 str. TW14359 8218160 YP_003079433.1 CDS ECSP_3595 NC_013008.1 3557701 3557907 R DNA binding protein complement(3557701..3557907) Escherichia coli O157:H7 str. TW14359 8218161 YP_003079434.1 CDS ECSP_3596 NC_013008.1 3558007 3558858 R hypothetical protein complement(3558007..3558858) Escherichia coli O157:H7 str. TW14359 8218162 YP_003079435.1 CDS ypjA NC_013008.1 3559285 3563871 R adhesin complement(3559285..3563871) Escherichia coli O157:H7 str. TW14359 8218163 YP_003079436.1 CDS ECSP_3598 NC_013008.1 3563936 3564055 R hypothetical protein complement(3563936..3564055) Escherichia coli O157:H7 str. TW14359 8218164 YP_003079437.1 CDS ECSP_3599 NC_013008.1 3564210 3564353 R hypothetical protein complement(3564210..3564353) Escherichia coli O157:H7 str. TW14359 8218165 YP_003079438.1 CDS ECSP_3600 NC_013008.1 3564807 3566156 R hypothetical protein complement(3564807..3566156) Escherichia coli O157:H7 str. TW14359 8218166 YP_003079439.1 CDS ECSP_3601 NC_013008.1 3566664 3566816 R hypothetical protein complement(3566664..3566816) Escherichia coli O157:H7 str. TW14359 8218167 YP_003079440.1 CDS ygaT NC_013008.1 3570133 3571110 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3570133..3571110 Escherichia coli O157:H7 str. TW14359 8218170 YP_003079441.1 CDS ygaF NC_013008.1 3571130 3572398 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3571130..3572398 Escherichia coli O157:H7 str. TW14359 8218171 YP_003079442.1 CDS gabD NC_013008.1 3572421 3573869 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3572421..3573869 Escherichia coli O157:H7 str. TW14359 8218172 YP_003079443.1 CDS gabT NC_013008.1 3573883 3575163 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3573883..3575163 Escherichia coli O157:H7 str. TW14359 8218173 YP_003079444.1 CDS gabP NC_013008.1 3575401 3576801 D gamma-aminobutyrate transporter 3575401..3576801 Escherichia coli O157:H7 str. TW14359 8218174 YP_003079445.1 CDS csiR NC_013008.1 3576822 3577484 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3576822..3577484 Escherichia coli O157:H7 str. TW14359 8218175 YP_003079446.1 CDS ygaU NC_013008.1 3577485 3577934 R LysM domain/BON superfamily protein complement(3577485..3577934) Escherichia coli O157:H7 str. TW14359 8218176 YP_003079447.1 CDS yqaE NC_013008.1 3578018 3578176 R hypothetical protein complement(3578018..3578176) Escherichia coli O157:H7 str. TW14359 8218177 YP_003079448.1 CDS ygaV NC_013008.1 3578359 3578658 D DNA-binding transcriptional regulator 3578359..3578658 Escherichia coli O157:H7 str. TW14359 8218178 YP_003079449.1 CDS ygaP NC_013008.1 3578668 3579186 D inner membrane protein with hydrolase activity 3578668..3579186 Escherichia coli O157:H7 str. TW14359 8218179 YP_003079450.1 CDS stpA NC_013008.1 3579239 3579643 R DNA binding protein, nucleoid-associated complement(3579239..3579643) Escherichia coli O157:H7 str. TW14359 8218180 YP_003079451.1 CDS ECSP_3615 NC_013008.1 3580057 3580185 D hypothetical protein 3580057..3580185 Escherichia coli O157:H7 str. TW14359 8218181 YP_003079452.1 CDS ygaW NC_013008.1 3580311 3580760 D inner membrane protein 3580311..3580760 Escherichia coli O157:H7 str. TW14359 8218182 YP_003079453.1 CDS ygaC NC_013008.1 3580797 3581141 R hypothetical protein complement(3580797..3581141) Escherichia coli O157:H7 str. TW14359 8218183 YP_003079454.1 CDS ygaM NC_013008.1 3581281 3581622 D hypothetical protein 3581281..3581622 Escherichia coli O157:H7 str. TW14359 8218184 YP_003079455.1 CDS ECSP_3619 NC_013008.1 3581772 3583106 R hypothetical protein complement(3581772..3583106) Escherichia coli O157:H7 str. TW14359 8218185 YP_003079456.1 CDS ECSP_3620 NC_013008.1 3583194 3583625 D hypothetical protein 3583194..3583625 Escherichia coli O157:H7 str. TW14359 8218186 YP_003079457.1 CDS nrdH NC_013008.1 3583834 3584079 D glutaredoxin-like protein 3583834..3584079 Escherichia coli O157:H7 str. TW14359 8218187 YP_003079458.1 CDS nrdI NC_013008.1 3584076 3584486 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3584076..3584486 Escherichia coli O157:H7 str. TW14359 8218188 YP_003079459.1 CDS nrdE NC_013008.1 3584459 3586603 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3584459..3586603 Escherichia coli O157:H7 str. TW14359 8218189 YP_003079460.1 CDS nrdF NC_013008.1 3586613 3587572 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3586613..3587572 Escherichia coli O157:H7 str. TW14359 8218190 YP_003079461.1 CDS proV NC_013008.1 3587928 3589130 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3587928..3589130 Escherichia coli O157:H7 str. TW14359 8218191 YP_003079462.1 CDS proW NC_013008.1 3589123 3590187 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3589123..3590187 Escherichia coli O157:H7 str. TW14359 8218192 YP_003079463.1 CDS proX NC_013008.1 3590244 3591236 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3590244..3591236 Escherichia coli O157:H7 str. TW14359 8218193 YP_003079464.1 CDS ECSP_3628 NC_013008.1 3591428 3592612 D major facilitator superfamily transporter 3591428..3592612 Escherichia coli O157:H7 str. TW14359 8218194 YP_003079465.1 CDS ygaZ NC_013008.1 3592736 3593473 D transporter 3592736..3593473 Escherichia coli O157:H7 str. TW14359 8218195 YP_003079466.1 CDS ygaH NC_013008.1 3593463 3593798 D hypothetical protein 3593463..3593798 Escherichia coli O157:H7 str. TW14359 8218196 YP_003079467.1 CDS mprA NC_013008.1 3593889 3594419 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3593889..3594419 Escherichia coli O157:H7 str. TW14359 8218197 YP_003079468.1 CDS emrA NC_013008.1 3594546 3595718 D multidrug efflux system 3594546..3595718 Escherichia coli O157:H7 str. TW14359 8218198 YP_003079469.1 CDS emrB NC_013008.1 3595735 3597273 D multidrug efflux system protein 3595735..3597273 Escherichia coli O157:H7 str. TW14359 8218199 YP_003079470.1 CDS luxS NC_013008.1 3597337 3597852 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(3597337..3597852) Escherichia coli O157:H7 str. TW14359 8218200 YP_003079471.1 CDS gshA NC_013008.1 3598002 3599558 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(3598002..3599558) Escherichia coli O157:H7 str. TW14359 8218201 YP_003079472.1 CDS yqaA NC_013008.1 3599631 3600059 R hypothetical protein complement(3599631..3600059) Escherichia coli O157:H7 str. TW14359 8218202 YP_003079473.1 CDS yqaB NC_013008.1 3600056 3600622 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(3600056..3600622) Escherichia coli O157:H7 str. TW14359 8218203 YP_003079474.1 CDS csrA NC_013008.1 3601850 3602035 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(3601850..3602035) Escherichia coli O157:H7 str. TW14359 8218209 YP_003079475.1 CDS alaS NC_013008.1 3602270 3604900 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(3602270..3604900) Escherichia coli O157:H7 str. TW14359 8218210 YP_003079476.1 CDS ECSP_3645 NC_013008.1 3604586 3604987 D hypothetical protein 3604586..3604987 Escherichia coli O157:H7 str. TW14359 8218211 YP_003079477.1 CDS recX NC_013008.1 3605028 3605528 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(3605028..3605528) Escherichia coli O157:H7 str. TW14359 8218212 YP_003079478.1 CDS recA NC_013008.1 3605596 3606657 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(3605596..3606657) Escherichia coli O157:H7 str. TW14359 8218213 YP_003079479.1 CDS ygaD NC_013008.1 3606737 3607234 R competence damage-inducible protein A complement(3606737..3607234) Escherichia coli O157:H7 str. TW14359 8218214 YP_003079480.1 CDS mltB NC_013008.1 3607379 3608464 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(3607379..3608464) Escherichia coli O157:H7 str. TW14359 8218215 YP_003079481.1 CDS srlB NC_013008.1 3610250 3610621 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3610250..3610621 Escherichia coli O157:H7 str. TW14359 8218218 YP_003079482.1 CDS srlD NC_013008.1 3610625 3611404 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3610625..3611404 Escherichia coli O157:H7 str. TW14359 8218219 YP_003079483.1 CDS gutM NC_013008.1 3611510 3611869 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3611510..3611869 Escherichia coli O157:H7 str. TW14359 8218220 YP_003079484.1 CDS srlR NC_013008.1 3611936 3612709 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3611936..3612709 Escherichia coli O157:H7 str. TW14359 8218221 YP_003079485.1 CDS gutQ NC_013008.1 3612702 3613667 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3612702..3613667 Escherichia coli O157:H7 str. TW14359 8218222 YP_003079486.1 CDS norR NC_013008.1 3613664 3615178 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator complement(3613664..3615178) Escherichia coli O157:H7 str. TW14359 8218223 YP_003079487.1 CDS norV NC_013008.1 3615365 3616804 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3615365..3616804 Escherichia coli O157:H7 str. TW14359 8218224 YP_003079488.1 CDS norW NC_013008.1 3616801 3617934 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3616801..3617934 Escherichia coli O157:H7 str. TW14359 8218225 YP_003079489.1 CDS hypF NC_013008.1 3618062 3620314 R carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases complement(3618062..3620314) Escherichia coli O157:H7 str. TW14359 8218226 YP_003079490.1 CDS hydN NC_013008.1 3620467 3620994 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(3620467..3620994) Escherichia coli O157:H7 str. TW14359 8218227 YP_003079491.1 CDS ascG NC_013008.1 3621143 3622156 R DNA-binding transcriptional repressor complement(3621143..3622156) Escherichia coli O157:H7 str. TW14359 8218228 YP_003079492.1 CDS ascF NC_013008.1 3622413 3623870 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC 3622413..3623870 Escherichia coli O157:H7 str. TW14359 8218229 YP_003079493.1 CDS ascB NC_013008.1 3623879 3625303 D cryptic 6-phospho-beta-glucosidase 3623879..3625303 Escherichia coli O157:H7 str. TW14359 8218230 YP_003079494.1 CDS hycI NC_013008.1 3625427 3625897 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3625427..3625897) Escherichia coli O157:H7 str. TW14359 8218231 YP_003079495.1 CDS hycH NC_013008.1 3625890 3626300 R protein required for maturation of hydrogenase 3 complement(3625890..3626300) Escherichia coli O157:H7 str. TW14359 8218232 YP_003079496.1 CDS hycG NC_013008.1 3626297 3627064 R hydrogenase 3 and formate hydrogenase complex subunit HycG complement(3626297..3627064) Escherichia coli O157:H7 str. TW14359 8218233 YP_003079497.1 CDS hycF NC_013008.1 3627064 3627606 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3627064..3627606) Escherichia coli O157:H7 str. TW14359 8218234 YP_003079498.1 CDS hycE NC_013008.1 3627616 3629325 R hydrogenase 3, large subunit complement(3627616..3629325) Escherichia coli O157:H7 str. TW14359 8218235 YP_003079499.1 CDS hycD NC_013008.1 3629343 3630266 R hydrogenase 3, membrane subunit complement(3629343..3630266) Escherichia coli O157:H7 str. TW14359 8218236 YP_003079500.1 CDS hycC NC_013008.1 3630269 3632095 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3630269..3632095) Escherichia coli O157:H7 str. TW14359 8218237 YP_003079501.1 CDS hycB NC_013008.1 3632092 3632703 R hydrogenase 3, Fe-S subunit complement(3632092..3632703) Escherichia coli O157:H7 str. TW14359 8218238 YP_003079502.1 CDS hycA NC_013008.1 3632828 3633289 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3632828..3633289) Escherichia coli O157:H7 str. TW14359 8218239 YP_003079503.1 CDS ECSP_3674 NC_013008.1 3633323 3633460 R hypothetical protein complement(3633323..3633460) Escherichia coli O157:H7 str. TW14359 8218240 YP_003079504.1 CDS hypA NC_013008.1 3633501 3633851 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3633501..3633851 Escherichia coli O157:H7 str. TW14359 8218241 YP_003079505.1 CDS hypB NC_013008.1 3633855 3634727 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3633855..3634727 Escherichia coli O157:H7 str. TW14359 8218242 YP_003079506.1 CDS hypC NC_013008.1 3634718 3634990 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3634718..3634990 Escherichia coli O157:H7 str. TW14359 8218243 YP_003079507.1 CDS hypD NC_013008.1 3634990 3636111 D protein required for maturation of hydrogenases 3634990..3636111 Escherichia coli O157:H7 str. TW14359 8218244 YP_003079508.1 CDS hypE NC_013008.1 3636150 3637118 D carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 3636150..3637118 Escherichia coli O157:H7 str. TW14359 8218245 YP_003079509.1 CDS fhlA NC_013008.1 3637192 3639270 D DNA-binding transcriptional activator 3637192..3639270 Escherichia coli O157:H7 str. TW14359 8218246 YP_003079510.1 CDS ygbA NC_013008.1 3639307 3639660 R hypothetical protein complement(3639307..3639660) Escherichia coli O157:H7 str. TW14359 8218247 YP_003079511.1 CDS ECSP_3682 NC_013008.1 3639737 3639871 R hypothetical protein complement(3639737..3639871) Escherichia coli O157:H7 str. TW14359 8218248 YP_003079512.1 CDS mutS NC_013008.1 3639947 3642508 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3639947..3642508 Escherichia coli O157:H7 str. TW14359 8218249 YP_003079513.1 CDS pphB NC_013008.1 3642614 3643270 D serine/threonine-specific protein phosphatase 2 3642614..3643270 Escherichia coli O157:H7 str. TW14359 8218250 YP_003079514.1 CDS ECSP_3685 NC_013008.1 3643311 3643547 R hypothetical protein complement(3643311..3643547) Escherichia coli O157:H7 str. TW14359 8218251 YP_003079515.1 CDS ECSP_3686 NC_013008.1 3643558 3644985 R hypothetical protein complement(3643558..3644985) Escherichia coli O157:H7 str. TW14359 8218252 YP_003079516.1 CDS ECSP_3687 NC_013008.1 3644985 3645578 R decarboxylase complement(3644985..3645578) Escherichia coli O157:H7 str. TW14359 8218253 YP_003079517.1 CDS ECSP_3688 NC_013008.1 3645725 3646132 D regulator 3645725..3646132 Escherichia coli O157:H7 str. TW14359 8218254 YP_003079518.1 CDS rpoS NC_013008.1 3646252 3647244 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(3646252..3647244) Escherichia coli O157:H7 str. TW14359 8218255 YP_003079519.1 CDS nlpD NC_013008.1 3647307 3648398 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3647307..3648398) Escherichia coli O157:H7 str. TW14359 8218256 YP_003079520.1 CDS pcm NC_013008.1 3648538 3649164 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3648538..3649164) Escherichia coli O157:H7 str. TW14359 8218257 YP_003079521.1 CDS surE NC_013008.1 3649158 3649919 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3649158..3649919) Escherichia coli O157:H7 str. TW14359 8218258 YP_003079522.1 CDS truD NC_013008.1 3649900 3650949 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3649900..3650949) Escherichia coli O157:H7 str. TW14359 8218259 YP_003079523.1 CDS ispF NC_013008.1 3650946 3651425 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3650946..3651425) Escherichia coli O157:H7 str. TW14359 8218260 YP_003079524.1 CDS ispD NC_013008.1 3651425 3652135 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3651425..3652135) Escherichia coli O157:H7 str. TW14359 8218261 YP_003079525.1 CDS ftsB NC_013008.1 3652154 3652465 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3652154..3652465) Escherichia coli O157:H7 str. TW14359 8218262 YP_003079526.1 CDS ygbE NC_013008.1 3652659 3652982 R hypothetical protein complement(3652659..3652982) Escherichia coli O157:H7 str. TW14359 8218263 YP_003079527.1 CDS cysC NC_013008.1 3653032 3653637 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3653032..3653637) Escherichia coli O157:H7 str. TW14359 8218264 YP_003079528.1 CDS cysN NC_013008.1 3653637 3655064 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3653637..3655064) Escherichia coli O157:H7 str. TW14359 8218265 YP_003079529.1 CDS cysD NC_013008.1 3655066 3655974 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3655066..3655974) Escherichia coli O157:H7 str. TW14359 8218266 YP_003079530.1 CDS iap NC_013008.1 3656226 3657263 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3656226..3657263 Escherichia coli O157:H7 str. TW14359 8218267 YP_003079531.1 CDS ygbF NC_013008.1 3657653 3657946 R hypothetical protein complement(3657653..3657946) Escherichia coli O157:H7 str. TW14359 8218268 YP_003079532.1 CDS ygbT NC_013008.1 3657943 3658866 R hypothetical protein complement(3657943..3658866) Escherichia coli O157:H7 str. TW14359 8218269 YP_003079533.1 CDS ECSP_3704 NC_013008.1 3658863 3659513 R hypothetical protein complement(3658863..3659513) Escherichia coli O157:H7 str. TW14359 8218270 YP_003079534.1 CDS ECSP_3705 NC_013008.1 3659495 3660241 R hypothetical protein complement(3659495..3660241) Escherichia coli O157:H7 str. TW14359 8218271 YP_003079535.1 CDS ECSP_3706 NC_013008.1 3660252 3661307 R hypothetical protein complement(3660252..3661307) Escherichia coli O157:H7 str. TW14359 8218272 YP_003079536.1 CDS ECSP_3707 NC_013008.1 3661319 3661855 R hypothetical protein complement(3661319..3661855) Escherichia coli O157:H7 str. TW14359 8218273 YP_003079537.1 CDS ECSP_3708 NC_013008.1 3661852 3663414 R hypothetical protein complement(3661852..3663414) Escherichia coli O157:H7 str. TW14359 8218274 YP_003079538.1 CDS ygcB NC_013008.1 3663512 3666169 R helicase complement(3663512..3666169) Escherichia coli O157:H7 str. TW14359 8218275 YP_003079539.1 CDS ECSP_3710 NC_013008.1 3666403 3666555 R hypothetical protein complement(3666403..3666555) Escherichia coli O157:H7 str. TW14359 8218276 YP_003079540.1 CDS cysH NC_013008.1 3666819 3667553 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3666819..3667553) Escherichia coli O157:H7 str. TW14359 8218277 YP_003079541.1 CDS cysI NC_013008.1 3667627 3669339 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3667627..3669339) Escherichia coli O157:H7 str. TW14359 8218278 YP_003079542.1 CDS cysJ NC_013008.1 3669339 3671138 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3669339..3671138) Escherichia coli O157:H7 str. TW14359 8218279 YP_003079543.1 CDS ygcM NC_013008.1 3671454 3671819 D 6-pyruvoyl tetrahydrobiopterin synthase 3671454..3671819 Escherichia coli O157:H7 str. TW14359 8218280 YP_003079544.1 CDS ygcN NC_013008.1 3671897 3673168 D oxidoreductase 3671897..3673168 Escherichia coli O157:H7 str. TW14359 8218281 YP_003079545.1 CDS ygcO NC_013008.1 3673159 3673419 D 4Fe-4S cluster-containing protein 3673159..3673419 Escherichia coli O157:H7 str. TW14359 8218282 YP_003079546.1 CDS ygcP NC_013008.1 3673436 3674011 D anti-terminator regulatory protein 3673436..3674011 Escherichia coli O157:H7 str. TW14359 8218283 YP_003079547.1 CDS ygcR NC_013008.1 3675016 3675795 R flavoprotein complement(3675016..3675795) Escherichia coli O157:H7 str. TW14359 8218285 YP_003079548.1 CDS ygcU NC_013008.1 3677203 3678657 R FAD containing dehydrogenase complement(3677203..3678657) Escherichia coli O157:H7 str. TW14359 8218287 YP_003079549.1 CDS ygcW NC_013008.1 3678727 3679512 R deoxygluconate dehydrogenase complement(3678727..3679512) Escherichia coli O157:H7 str. TW14359 8218288 YP_003079550.1 CDS yqcE NC_013008.1 3679831 3681108 D transporter 3679831..3681108 Escherichia coli O157:H7 str. TW14359 8218289 YP_003079551.1 CDS ygcE NC_013008.1 3681135 3682613 D kinase 3681135..3682613 Escherichia coli O157:H7 str. TW14359 8218290 YP_003079553.1 CDS ygcF NC_013008.1 3683678 3684349 R hypothetical protein complement(3683678..3684349) Escherichia coli O157:H7 str. TW14359 8218292 YP_003079554.1 CDS ECSP_3727 NC_013008.1 3684630 3685124 D LemA family protein 3684630..3685124 Escherichia coli O157:H7 str. TW14359 8218293 YP_003079555.1 CDS ECSP_3728 NC_013008.1 3685138 3685812 D hypothetical protein 3685138..3685812 Escherichia coli O157:H7 str. TW14359 8218294 YP_003079556.1 CDS ECSP_3729 NC_013008.1 3686046 3687194 D hypothetical protein 3686046..3687194 Escherichia coli O157:H7 str. TW14359 8218295 YP_003079557.1 CDS ECSP_3730 NC_013008.1 3687191 3688105 D hypothetical protein 3687191..3688105 Escherichia coli O157:H7 str. TW14359 8218296 YP_003079558.1 CDS eno NC_013008.1 3688165 3689463 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3688165..3689463) Escherichia coli O157:H7 str. TW14359 8218297 YP_003079559.1 CDS pyrG NC_013008.1 3689551 3691188 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3689551..3691188) Escherichia coli O157:H7 str. TW14359 8218298 YP_003079560.1 CDS mazG NC_013008.1 3691416 3692207 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(3691416..3692207) Escherichia coli O157:H7 str. TW14359 8218299 YP_003079561.1 CDS chpA NC_013008.1 3692278 3692613 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3692278..3692613) Escherichia coli O157:H7 str. TW14359 8218300 YP_003079562.1 CDS chpR NC_013008.1 3692613 3692861 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(3692613..3692861) Escherichia coli O157:H7 str. TW14359 8218301 YP_003079563.1 CDS relA NC_013008.1 3692939 3695173 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3692939..3695173) Escherichia coli O157:H7 str. TW14359 8218302 YP_003079564.1 CDS rumA NC_013008.1 3695221 3696522 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3695221..3696522) Escherichia coli O157:H7 str. TW14359 8218303 YP_003079565.1 CDS barA NC_013008.1 3696579 3699335 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3696579..3699335 Escherichia coli O157:H7 str. TW14359 8218304 YP_003079566.1 CDS gudD NC_013008.1 3699568 3700908 R D-glucarate dehydratase complement(3699568..3700908) Escherichia coli O157:H7 str. TW14359 8218305 YP_003079567.1 CDS gudP NC_013008.1 3702271 3703623 R D-glucarate transporter complement(3702271..3703623) Escherichia coli O157:H7 str. TW14359 8218307 YP_003079568.1 CDS yqcA NC_013008.1 3704058 3704507 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3704058..3704507) Escherichia coli O157:H7 str. TW14359 8218308 YP_003079569.1 CDS truC NC_013008.1 3704525 3705307 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3704525..3705307) Escherichia coli O157:H7 str. TW14359 8218309 YP_003079570.1 CDS yqcC NC_013008.1 3705307 3705636 R hypothetical protein complement(3705307..3705636) Escherichia coli O157:H7 str. TW14359 8218310 YP_003079571.1 CDS syd NC_013008.1 3706258 3706803 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3706258..3706803) Escherichia coli O157:H7 str. TW14359 8218311 YP_003079572.1 CDS queF NC_013008.1 3706871 3707719 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3706871..3707719 Escherichia coli O157:H7 str. TW14359 8218312 YP_003079573.1 CDS ygdH NC_013008.1 3707831 3709195 D hypothetical protein 3707831..3709195 Escherichia coli O157:H7 str. TW14359 8218313 YP_003079574.1 CDS sdaC NC_013008.1 3709752 3711041 D serine transporter 3709752..3711041 Escherichia coli O157:H7 str. TW14359 8218314 YP_003079575.1 CDS sdaB NC_013008.1 3711099 3712466 D L-serine deaminase II 3711099..3712466 Escherichia coli O157:H7 str. TW14359 8218315 YP_003079576.1 CDS xni NC_013008.1 3712578 3713333 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3712578..3713333 Escherichia coli O157:H7 str. TW14359 8218316 YP_003079577.1 CDS fucO NC_013008.1 3713388 3714539 R L-1,2-propanediol oxidoreductase complement(3713388..3714539) Escherichia coli O157:H7 str. TW14359 8218317 YP_003079578.1 CDS fucA NC_013008.1 3714564 3715211 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3714564..3715211) Escherichia coli O157:H7 str. TW14359 8218318 YP_003079579.1 CDS fucP NC_013008.1 3715758 3717074 D L-fucose transporter 3715758..3717074 Escherichia coli O157:H7 str. TW14359 8218319 YP_003079580.1 CDS fucI NC_013008.1 3717107 3718882 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3717107..3718882 Escherichia coli O157:H7 str. TW14359 8218320 YP_003079581.1 CDS fucK NC_013008.1 3718961 3720409 D L-fuculokinase 3718961..3720409 Escherichia coli O157:H7 str. TW14359 8218321 YP_003079582.1 CDS fucU NC_013008.1 3720411 3720833 D L-fucose mutarotase 3720411..3720833 Escherichia coli O157:H7 str. TW14359 8218322 YP_003079583.1 CDS fucR NC_013008.1 3720891 3721622 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3720891..3721622 Escherichia coli O157:H7 str. TW14359 8218323 YP_003079584.1 CDS ygdE NC_013008.1 3721666 3722766 R RNA 2'-O-ribose methyltransferase complement(3721666..3722766) Escherichia coli O157:H7 str. TW14359 8218324 YP_003079585.1 CDS ygdD NC_013008.1 3722759 3723154 R hypothetical protein complement(3722759..3723154) Escherichia coli O157:H7 str. TW14359 8218325 YP_003079586.1 CDS gcvA NC_013008.1 3723173 3724090 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3723173..3724090) Escherichia coli O157:H7 str. TW14359 8218326 YP_003079587.1 CDS ygdI NC_013008.1 3724441 3724668 R hypothetical protein complement(3724441..3724668) Escherichia coli O157:H7 str. TW14359 8218327 YP_003079588.1 CDS csdA NC_013008.1 3724860 3726065 D cysteine sulfinate desulfinase 3724860..3726065 Escherichia coli O157:H7 str. TW14359 8218328 YP_003079589.1 CDS ygdK NC_013008.1 3726065 3726508 D Fe-S metabolism protein 3726065..3726508 Escherichia coli O157:H7 str. TW14359 8218329 YP_003079590.1 CDS ygdL NC_013008.1 3726559 3727365 R hypothetical protein complement(3726559..3727365) Escherichia coli O157:H7 str. TW14359 8218330 YP_003079591.1 CDS mltA NC_013008.1 3727604 3728701 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3727604..3728701) Escherichia coli O157:H7 str. TW14359 8218331 YP_003079592.1 CDS amiC NC_013008.1 3729280 3730533 R N-acetylmuramoyl-L-alanine amidase complement(3729280..3730533) Escherichia coli O157:H7 str. TW14359 8218335 YP_003079593.1 CDS argA NC_013008.1 3730765 3732096 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3730765..3732096 Escherichia coli O157:H7 str. TW14359 8218336 YP_003079594.1 CDS recD NC_013008.1 3732158 3733984 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3732158..3733984) Escherichia coli O157:H7 str. TW14359 8218337 YP_003079595.1 CDS recB NC_013008.1 3733984 3737526 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3733984..3737526) Escherichia coli O157:H7 str. TW14359 8218338 YP_003079596.1 CDS ptr NC_013008.1 3737519 3740407 R protease III complement(3737519..3740407) Escherichia coli O157:H7 str. TW14359 8218339 YP_003079597.1 CDS recC NC_013008.1 3740583 3743951 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3740583..3743951) Escherichia coli O157:H7 str. TW14359 8218340 YP_003079598.1 CDS ppdC NC_013008.1 3743964 3744287 R hypothetical protein complement(3743964..3744287) Escherichia coli O157:H7 str. TW14359 8218341 YP_003079599.1 CDS ygdB NC_013008.1 3744272 3744679 R hypothetical protein complement(3744272..3744679) Escherichia coli O157:H7 str. TW14359 8218342 YP_003079600.1 CDS ppdB NC_013008.1 3744676 3745239 R hypothetical protein complement(3744676..3745239) Escherichia coli O157:H7 str. TW14359 8218343 YP_003079601.1 CDS ppdA NC_013008.1 3745230 3745700 R hypothetical protein complement(3745230..3745700) Escherichia coli O157:H7 str. TW14359 8218344 YP_003079602.1 CDS thyA NC_013008.1 3745884 3746678 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3745884..3746678) Escherichia coli O157:H7 str. TW14359 8218345 YP_003079603.1 CDS lgt NC_013008.1 3746685 3747560 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3746685..3747560) Escherichia coli O157:H7 str. TW14359 8218346 YP_003079604.1 CDS ptsP NC_013008.1 3747711 3749957 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3747711..3749957) Escherichia coli O157:H7 str. TW14359 8218347 YP_003079605.1 CDS nudH NC_013008.1 3749970 3750500 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3749970..3750500) Escherichia coli O157:H7 str. TW14359 8218348 YP_003079606.1 CDS ECSP_3783 NC_013008.1 3750853 3750999 R hypothetical protein complement(3750853..3750999) Escherichia coli O157:H7 str. TW14359 8218349 YP_003079607.1 CDS mutH NC_013008.1 3751185 3751874 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3751185..3751874 Escherichia coli O157:H7 str. TW14359 8218350 YP_003079608.1 CDS ygdQ NC_013008.1 3751943 3752656 D inner membrane protein 3751943..3752656 Escherichia coli O157:H7 str. TW14359 8218351 YP_003079609.1 CDS ygdR NC_013008.1 3752794 3753012 D hypothetical protein 3752794..3753012 Escherichia coli O157:H7 str. TW14359 8218352 YP_003079610.1 CDS tas NC_013008.1 3753120 3754160 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3753120..3754160 Escherichia coli O157:H7 str. TW14359 8218353 YP_003079611.1 CDS ygeD NC_013008.1 3754192 3755385 R lysophospholipid transporter LplT complement(3754192..3755385) Escherichia coli O157:H7 str. TW14359 8218354 YP_003079612.1 CDS aas NC_013008.1 3755378 3757537 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3755378..3757537) Escherichia coli O157:H7 str. TW14359 8218355 YP_003079613.1 CDS galR NC_013008.1 3758123 3759154 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3758123..3759154 Escherichia coli O157:H7 str. TW14359 8218356 YP_003079614.1 CDS lysA NC_013008.1 3759161 3760423 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3759161..3760423) Escherichia coli O157:H7 str. TW14359 8218357 YP_003079615.1 CDS lysR NC_013008.1 3760545 3761480 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3760545..3761480 Escherichia coli O157:H7 str. TW14359 8218358 YP_003079616.1 CDS ygeA NC_013008.1 3761467 3762159 R racemase complement(3761467..3762159) Escherichia coli O157:H7 str. TW14359 8218359 YP_003079617.1 CDS araE NC_013008.1 3762288 3763706 R arabinose transporter complement(3762288..3763706) Escherichia coli O157:H7 str. TW14359 8218360 YP_003079618.1 CDS kduD NC_013008.1 3764021 3764782 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3764021..3764782) Escherichia coli O157:H7 str. TW14359 8218361 YP_003079619.1 CDS kduI NC_013008.1 3764812 3765648 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3764812..3765648) Escherichia coli O157:H7 str. TW14359 8218362 YP_003079620.1 CDS yqeF NC_013008.1 3765935 3767116 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3765935..3767116) Escherichia coli O157:H7 str. TW14359 8218363 YP_003079621.1 CDS yqeG NC_013008.1 3767371 3768600 D transporter 3767371..3768600 Escherichia coli O157:H7 str. TW14359 8218364 YP_003079622.1 CDS yqeH NC_013008.1 3769060 3769692 D hypothetical protein 3769060..3769692 Escherichia coli O157:H7 str. TW14359 8218365 YP_003079623.1 CDS yqeI NC_013008.1 3770026 3770835 D transcriptional regulator 3770026..3770835 Escherichia coli O157:H7 str. TW14359 8218366 YP_003079624.1 CDS yqeJ NC_013008.1 3770832 3771311 D hypothetical protein 3770832..3771311 Escherichia coli O157:H7 str. TW14359 8218367 YP_003079625.1 CDS yqeK NC_013008.1 3771460 3771885 R hypothetical protein complement(3771460..3771885) Escherichia coli O157:H7 str. TW14359 8218368 YP_003079626.1 CDS ECSP_3803 NC_013008.1 3772025 3772261 R hypothetical protein complement(3772025..3772261) Escherichia coli O157:H7 str. TW14359 8218369 YP_003079627.1 CDS ygeF NC_013008.1 3772315 3772806 D hypothetical protein 3772315..3772806 Escherichia coli O157:H7 str. TW14359 8218370 YP_003079628.1 CDS ygeG NC_013008.1 3773032 3773523 D chaperone 3773032..3773523 Escherichia coli O157:H7 str. TW14359 8218371 YP_003079629.1 CDS ygeH NC_013008.1 3773857 3775233 D transcriptional regulator 3773857..3775233 Escherichia coli O157:H7 str. TW14359 8218372 YP_003079630.1 CDS ygeI NC_013008.1 3775400 3775618 D hypothetical protein 3775400..3775618 Escherichia coli O157:H7 str. TW14359 8218373 YP_003079631.1 CDS pbl NC_013008.1 3775703 3776206 D lytic transglycosylase 3775703..3776206 Escherichia coli O157:H7 str. TW14359 8218374 YP_003079632.1 CDS ECSP_3809 NC_013008.1 3776225 3776857 R 2-component transcriptional regulator complement(3776225..3776857) Escherichia coli O157:H7 str. TW14359 8218375 YP_003079633.1 CDS ECSP_3810 NC_013008.1 3776836 3777003 R hypothetical protein complement(3776836..3777003) Escherichia coli O157:H7 str. TW14359 8218376 YP_003079634.1 CDS ECSP_3811 NC_013008.1 3777080 3777511 R hypothetical protein complement(3777080..3777511) Escherichia coli O157:H7 str. TW14359 8218377 YP_003079635.1 CDS ECSP_3812 NC_013008.1 3777528 3777788 R hypothetical protein complement(3777528..3777788) Escherichia coli O157:H7 str. TW14359 8218378 YP_003079636.1 CDS ygeO NC_013008.1 3777730 3778311 R hypothetical protein complement(3777730..3778311) Escherichia coli O157:H7 str. TW14359 8218379 YP_003079637.1 CDS eprK NC_013008.1 3778327 3779061 R lipoprotein of type III secretion apparatus complement(3778327..3779061) Escherichia coli O157:H7 str. TW14359 8218380 YP_003079638.1 CDS eprJ NC_013008.1 3779058 3779390 R Type III secretion apparatus protein complement(3779058..3779390) Escherichia coli O157:H7 str. TW14359 8218381 YP_003079639.1 CDS eprI NC_013008.1 3779410 3779649 R type III secretion apparatus protein EprI complement(3779410..3779649) Escherichia coli O157:H7 str. TW14359 8218382 YP_003079640.1 CDS ECSP_3818 NC_013008.1 3781101 3781601 D hypothetical protein 3781101..3781601 Escherichia coli O157:H7 str. TW14359 8218384 YP_003079641.1 CDS epaS NC_013008.1 3781958 3783079 R Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; surface presentation of antigens protein SpaS complement(3781958..3783079) Escherichia coli O157:H7 str. TW14359 8218385 YP_003079642.1 CDS epaQ NC_013008.1 3783857 3784117 R type III secretion apparatus protein complement(3783857..3784117) Escherichia coli O157:H7 str. TW14359 8218387 YP_003079643.1 CDS spaP NC_013008.1 3784128 3784793 R part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP complement(3784128..3784793) Escherichia coli O157:H7 str. TW14359 8218388 YP_003079644.1 CDS epaO NC_013008.1 3784783 3785769 R involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; surface presentation of antigens protein SpaO complement(3784783..3785769) Escherichia coli O157:H7 str. TW14359 8218389 YP_003079645.1 CDS eivJ NC_013008.1 3785729 3786298 R type III secretion apparatus protein complement(3785729..3786298) Escherichia coli O157:H7 str. TW14359 8218390 YP_003079646.1 CDS ECSP_3825 NC_013008.1 3786371 3786604 R hypothetical protein complement(3786371..3786604) Escherichia coli O157:H7 str. TW14359 8218391 YP_003079647.1 CDS eivI NC_013008.1 3786582 3786917 R type III secretion apparatus protein complement(3786582..3786917) Escherichia coli O157:H7 str. TW14359 8218392 YP_003079648.1 CDS eivC NC_013008.1 3787030 3788349 R Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase; ATP synthase SpaL complement(3787030..3788349) Escherichia coli O157:H7 str. TW14359 8218393 YP_003079649.1 CDS eivA NC_013008.1 3788354 3790414 R type III secretion apparatus protein complement(3788354..3790414) Escherichia coli O157:H7 str. TW14359 8218394 YP_003079650.1 CDS eivE NC_013008.1 3790407 3791552 R hypothetical protein complement(3790407..3791552) Escherichia coli O157:H7 str. TW14359 8218395 YP_003079651.1 CDS eivG NC_013008.1 3791557 3793260 R type III secretion apparatus protein complement(3791557..3793260) Escherichia coli O157:H7 str. TW14359 8218396 YP_003079652.1 CDS eivF NC_013008.1 3793257 3794006 R regulatory protein for type III secretion apparatus complement(3793257..3794006) Escherichia coli O157:H7 str. TW14359 8218397 YP_003079653.1 CDS ECSP_3832 NC_013008.1 3794352 3794531 R hypothetical protein complement(3794352..3794531) Escherichia coli O157:H7 str. TW14359 8218398 YP_003079654.1 CDS ygeR NC_013008.1 3796589 3797344 R hypothetical protein complement(3796589..3797344) Escherichia coli O157:H7 str. TW14359 8218401 YP_003079655.1 CDS xdhA NC_013008.1 3797799 3800057 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3797799..3800057 Escherichia coli O157:H7 str. TW14359 8218402 YP_003079656.1 CDS xdhB NC_013008.1 3800068 3800946 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3800068..3800946 Escherichia coli O157:H7 str. TW14359 8218403 YP_003079657.1 CDS xdhC NC_013008.1 3800943 3801422 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3800943..3801422 Escherichia coli O157:H7 str. TW14359 8218404 YP_003079658.1 CDS ygeV NC_013008.1 3801462 3803240 R DNA-binding transcriptional regulator complement(3801462..3803240) Escherichia coli O157:H7 str. TW14359 8218405 YP_003079659.1 CDS ygeW NC_013008.1 3803716 3804906 D aspartate/ornithine carbamoyltransferase 3803716..3804906 Escherichia coli O157:H7 str. TW14359 8218406 YP_003079660.1 CDS ygeX NC_013008.1 3804964 3806160 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3804964..3806160 Escherichia coli O157:H7 str. TW14359 8218407 YP_003079661.1 CDS ygeY NC_013008.1 3806218 3807429 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3806218..3807429 Escherichia coli O157:H7 str. TW14359 8218408 YP_003079662.1 CDS hyuA NC_013008.1 3807482 3808867 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3807482..3808867 Escherichia coli O157:H7 str. TW14359 8218409 YP_003079663.1 CDS yqeA NC_013008.1 3808915 3809847 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3808915..3809847 Escherichia coli O157:H7 str. TW14359 8218410 YP_003079664.1 CDS yqeB NC_013008.1 3809888 3811513 R hypothetical protein complement(3809888..3811513) Escherichia coli O157:H7 str. TW14359 8218411 YP_003079665.1 CDS yqeC NC_013008.1 3811561 3812331 R hypothetical protein complement(3811561..3812331) Escherichia coli O157:H7 str. TW14359 8218412 YP_003079666.1 CDS ygfJ NC_013008.1 3812434 3813012 D hypothetical protein 3812434..3813012 Escherichia coli O157:H7 str. TW14359 8218413 YP_003079667.1 CDS ygfK NC_013008.1 3813334 3816432 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3813334..3816432 Escherichia coli O157:H7 str. TW14359 8218414 YP_003079668.1 CDS ssnA NC_013008.1 3816435 3817763 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3816435..3817763 Escherichia coli O157:H7 str. TW14359 8218415 YP_003079669.1 CDS ygfM NC_013008.1 3817813 3818592 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3817813..3818592 Escherichia coli O157:H7 str. TW14359 8218416 YP_003079670.1 CDS xdhD NC_013008.1 3818589 3821459 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3818589..3821459 Escherichia coli O157:H7 str. TW14359 8218417 YP_003079671.1 CDS ygfO NC_013008.1 3821624 3823024 D transporter 3821624..3823024 Escherichia coli O157:H7 str. TW14359 8218418 YP_003079672.1 CDS guaD NC_013008.1 3823039 3824358 D Catalyzes the deamination of guanine; guanine deaminase 3823039..3824358 Escherichia coli O157:H7 str. TW14359 8218419 YP_003079673.1 CDS ygfQ NC_013008.1 3824394 3825761 D transporter 3824394..3825761 Escherichia coli O157:H7 str. TW14359 8218420 YP_003079674.1 CDS ygfS NC_013008.1 3825797 3826192 R oxidoreductase complement(3825797..3826192) Escherichia coli O157:H7 str. TW14359 8218421 YP_003079675.1 CDS ygfT NC_013008.1 3826285 3828204 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3826285..3828204) Escherichia coli O157:H7 str. TW14359 8218422 YP_003079676.1 CDS ygfU NC_013008.1 3828640 3830088 D transporter 3828640..3830088 Escherichia coli O157:H7 str. TW14359 8218423 YP_003079677.1 CDS idi NC_013008.1 3830338 3830886 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3830338..3830886 Escherichia coli O157:H7 str. TW14359 8218424 YP_003079678.1 CDS lysS NC_013008.1 3830929 3832446 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3830929..3832446) Escherichia coli O157:H7 str. TW14359 8218425 YP_003079679.1 CDS recJ NC_013008.1 3833645 3835378 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3833645..3835378) Escherichia coli O157:H7 str. TW14359 8218426 YP_003079680.1 CDS dsbC NC_013008.1 3835384 3836094 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3835384..3836094) Escherichia coli O157:H7 str. TW14359 8218427 YP_003079681.1 CDS xerD NC_013008.1 3836119 3837015 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3836119..3837015) Escherichia coli O157:H7 str. TW14359 8218428 YP_003079682.1 CDS fldB NC_013008.1 3837127 3837648 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3837127..3837648 Escherichia coli O157:H7 str. TW14359 8218429 YP_003079683.1 CDS ygfX NC_013008.1 3837688 3838095 R hypothetical protein complement(3837688..3838095) Escherichia coli O157:H7 str. TW14359 8218430 YP_003079684.1 CDS ygfY NC_013008.1 3838076 3838342 R hypothetical protein complement(3838076..3838342) Escherichia coli O157:H7 str. TW14359 8218431 YP_003079685.1 CDS ygfZ NC_013008.1 3838585 3839565 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3838585..3839565 Escherichia coli O157:H7 str. TW14359 8218432 YP_003079686.1 CDS yqfA NC_013008.1 3839642 3840301 R oxidoreductase complement(3839642..3840301) Escherichia coli O157:H7 str. TW14359 8218433 YP_003079687.1 CDS yqfB NC_013008.1 3840465 3840776 R hypothetical protein complement(3840465..3840776) Escherichia coli O157:H7 str. TW14359 8218434 YP_003079688.1 CDS bglA NC_013008.1 3840815 3842254 D 6-phospho-beta-glucosidase 3840815..3842254 Escherichia coli O157:H7 str. TW14359 8218435 YP_003079689.1 CDS gcvP NC_013008.1 3842420 3845293 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3842420..3845293) Escherichia coli O157:H7 str. TW14359 8218436 YP_003079690.1 CDS gcvH NC_013008.1 3845411 3845800 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3845411..3845800) Escherichia coli O157:H7 str. TW14359 8218437 YP_003079691.1 CDS gcvT NC_013008.1 3845824 3846918 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3845824..3846918) Escherichia coli O157:H7 str. TW14359 8218438 YP_003079692.1 CDS visC NC_013008.1 3847366 3848568 R hypothetical protein complement(3847366..3848568) Escherichia coli O157:H7 str. TW14359 8218439 YP_003079693.1 CDS ubiH NC_013008.1 3848592 3849770 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3848592..3849770) Escherichia coli O157:H7 str. TW14359 8218440 YP_003079694.1 CDS pepP NC_013008.1 3849767 3851092 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3849767..3851092) Escherichia coli O157:H7 str. TW14359 8218441 YP_003079695.1 CDS ygfB NC_013008.1 3851118 3851696 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3851118..3851696) Escherichia coli O157:H7 str. TW14359 8218442 YP_003079696.1 CDS zapA NC_013008.1 3851864 3852193 D Z-ring-associated protein 3851864..3852193 Escherichia coli O157:H7 str. TW14359 8218443 YP_003079697.1 CDS ygfA NC_013008.1 3852493 3853041 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3852493..3853041 Escherichia coli O157:H7 str. TW14359 8218444 YP_003079699.1 CDS serA NC_013008.1 3853823 3855055 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3853823..3855055) Escherichia coli O157:H7 str. TW14359 8218446 YP_003079700.1 CDS rpiA NC_013008.1 3855310 3855969 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3855310..3855969) Escherichia coli O157:H7 str. TW14359 8218447 YP_003079701.1 CDS argP NC_013008.1 3856352 3857245 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3856352..3857245 Escherichia coli O157:H7 str. TW14359 8218448 YP_003079702.1 CDS sbm NC_013008.1 3857449 3859593 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3857449..3859593 Escherichia coli O157:H7 str. TW14359 8218449 YP_003079703.1 CDS argK NC_013008.1 3859586 3860581 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3859586..3860581 Escherichia coli O157:H7 str. TW14359 8218450 YP_003079704.1 CDS ygfG NC_013008.1 3860592 3861377 D catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3860592..3861377 Escherichia coli O157:H7 str. TW14359 8218451 YP_003079705.1 CDS ygfH NC_013008.1 3861401 3862879 D propionyl-CoA:succinate-CoA transferase 3861401..3862879 Escherichia coli O157:H7 str. TW14359 8218452 YP_003079706.1 CDS yggE NC_013008.1 3863939 3864679 R hypothetical protein complement(3863939..3864679) Escherichia coli O157:H7 str. TW14359 8218454 YP_003079707.1 CDS argO NC_013008.1 3864772 3865407 R Involved in the export of arginine; arginine exporter protein complement(3864772..3865407) Escherichia coli O157:H7 str. TW14359 8218455 YP_003079708.1 CDS mscS NC_013008.1 3865546 3866406 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3865546..3866406) Escherichia coli O157:H7 str. TW14359 8218456 YP_003079709.1 CDS fbaA NC_013008.1 3866764 3867843 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3866764..3867843) Escherichia coli O157:H7 str. TW14359 8218457 YP_003079710.1 CDS pgk NC_013008.1 3868058 3869221 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3868058..3869221) Escherichia coli O157:H7 str. TW14359 8218458 YP_003079711.1 CDS epd NC_013008.1 3869271 3870290 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3869271..3870290) Escherichia coli O157:H7 str. TW14359 8218459 YP_003079712.1 CDS ECSP_3894 NC_013008.1 3870662 3871093 D hypothetical protein 3870662..3871093 Escherichia coli O157:H7 str. TW14359 8218460 YP_003079713.1 CDS ECSP_3895 NC_013008.1 3871116 3871694 D hypothetical protein 3871116..3871694 Escherichia coli O157:H7 str. TW14359 8218461 YP_003079714.1 CDS ECSP_3896 NC_013008.1 3871695 3872402 D hypothetical protein 3871695..3872402 Escherichia coli O157:H7 str. TW14359 8218462 YP_003079715.1 CDS ECSP_3897 NC_013008.1 3872390 3873067 D ATP-binding protein of ABC transport system 3872390..3873067 Escherichia coli O157:H7 str. TW14359 8218463 YP_003079716.1 CDS ECSP_3898 NC_013008.1 3873061 3873738 D ATP-binding protein of ABC transport system 3873061..3873738 Escherichia coli O157:H7 str. TW14359 8218464 YP_003079717.1 CDS frcK NC_013008.1 3873710 3874423 R fructose transport system kinase complement(3873710..3874423) Escherichia coli O157:H7 str. TW14359 8218465 YP_003079718.1 CDS yggD NC_013008.1 3874420 3874929 R DNA-binding transcriptional regulator complement(3874420..3874929) Escherichia coli O157:H7 str. TW14359 8218466 YP_003079719.1 CDS yggF NC_013008.1 3874951 3875916 R fructose-1,6-bisphosphatase II-like protein complement(3874951..3875916) Escherichia coli O157:H7 str. TW14359 8218467 YP_003079720.1 CDS yggP NC_013008.1 3875913 3877190 R dehydrogenase complement(3875913..3877190) Escherichia coli O157:H7 str. TW14359 8218468 YP_003079721.1 CDS cmtA NC_013008.1 3877205 3878593 R fused mannitol-specific PTS enzymes: IIB component, IIC component complement(3877205..3878593) Escherichia coli O157:H7 str. TW14359 8218469 YP_003079722.1 CDS cmtB NC_013008.1 3878621 3879064 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3878621..3879064) Escherichia coli O157:H7 str. TW14359 8218470 YP_003079723.1 CDS tktA NC_013008.1 3879378 3881369 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3879378..3881369) Escherichia coli O157:H7 str. TW14359 8218471 YP_003079724.1 CDS yggG NC_013008.1 3881647 3882405 D peptidase 3881647..3882405 Escherichia coli O157:H7 str. TW14359 8218472 YP_003079725.1 CDS speB NC_013008.1 3882611 3883531 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3882611..3883531) Escherichia coli O157:H7 str. TW14359 8218473 YP_003079726.1 CDS ECSP_3908 NC_013008.1 3883667 3884398 R hypothetical protein complement(3883667..3884398) Escherichia coli O157:H7 str. TW14359 8218474 YP_003079727.1 CDS speA NC_013008.1 3884544 3886520 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3884544..3886520) Escherichia coli O157:H7 str. TW14359 8218475 YP_003079728.1 CDS yqgB NC_013008.1 3886529 3886660 R hypothetical protein complement(3886529..3886660) Escherichia coli O157:H7 str. TW14359 8218476 YP_003079729.1 CDS yqgC NC_013008.1 3886796 3887011 D hypothetical protein 3886796..3887011 Escherichia coli O157:H7 str. TW14359 8218477 YP_003079730.1 CDS yqgD NC_013008.1 3887008 3887259 R inner membrane protein complement(3887008..3887259) Escherichia coli O157:H7 str. TW14359 8218478 YP_003079731.1 CDS metK NC_013008.1 3887315 3888469 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3887315..3888469 Escherichia coli O157:H7 str. TW14359 8218479 YP_003079732.1 CDS galP NC_013008.1 3888906 3890300 D D-galactose transporter 3888906..3890300 Escherichia coli O157:H7 str. TW14359 8218480 YP_003079733.1 CDS sprT NC_013008.1 3890377 3890874 D hypothetical protein 3890377..3890874 Escherichia coli O157:H7 str. TW14359 8218481 YP_003079734.1 CDS endA NC_013008.1 3890969 3891676 D DNase I 3890969..3891676 Escherichia coli O157:H7 str. TW14359 8218482 YP_003079735.1 CDS yggJ NC_013008.1 3891756 3892487 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3891756..3892487 Escherichia coli O157:H7 str. TW14359 8218483 YP_003079736.1 CDS gshB NC_013008.1 3892500 3893447 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3892500..3893447 Escherichia coli O157:H7 str. TW14359 8218484 YP_003079737.1 CDS yqgE NC_013008.1 3893559 3894122 D hypothetical protein 3893559..3894122 Escherichia coli O157:H7 str. TW14359 8218485 YP_003079738.1 CDS yqgF NC_013008.1 3894122 3894538 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3894122..3894538 Escherichia coli O157:H7 str. TW14359 8218486 YP_003079739.1 CDS yggR NC_013008.1 3894729 3895709 R transporter complement(3894729..3895709) Escherichia coli O157:H7 str. TW14359 8218487 YP_003079740.1 CDS yggS NC_013008.1 3895727 3896431 D hypothetical protein 3895727..3896431 Escherichia coli O157:H7 str. TW14359 8218488 YP_003079741.1 CDS yggT NC_013008.1 3896449 3897015 D inner membrane protein 3896449..3897015 Escherichia coli O157:H7 str. TW14359 8218489 YP_003079742.1 CDS yggU NC_013008.1 3897012 3897302 D hypothetical protein 3897012..3897302 Escherichia coli O157:H7 str. TW14359 8218490 YP_003079743.1 CDS yggV NC_013008.1 3897310 3897903 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3897310..3897903 Escherichia coli O157:H7 str. TW14359 8218491 YP_003079744.1 CDS yggW NC_013008.1 3897896 3899032 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3897896..3899032 Escherichia coli O157:H7 str. TW14359 8218492 YP_003079745.1 CDS yggM NC_013008.1 3899275 3900282 R hypothetical protein complement(3899275..3900282) Escherichia coli O157:H7 str. TW14359 8218493 YP_003079746.1 CDS ansB NC_013008.1 3900399 3901445 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3900399..3901445) Escherichia coli O157:H7 str. TW14359 8218494 YP_003079747.1 CDS yggN NC_013008.1 3901621 3902340 R hypothetical protein complement(3901621..3902340) Escherichia coli O157:H7 str. TW14359 8218495 YP_003079748.1 CDS ECSP_3930 NC_013008.1 3902361 3902501 R hypothetical protein complement(3902361..3902501) Escherichia coli O157:H7 str. TW14359 8218496 YP_003079749.1 CDS yggL NC_013008.1 3902524 3902850 R hypothetical protein complement(3902524..3902850) Escherichia coli O157:H7 str. TW14359 8218497 YP_003079750.1 CDS trmB NC_013008.1 3902850 3903569 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3902850..3903569) Escherichia coli O157:H7 str. TW14359 8218498 YP_003079751.1 CDS mutY NC_013008.1 3903730 3904782 D adenine DNA glycosylase 3903730..3904782 Escherichia coli O157:H7 str. TW14359 8218499 YP_003079752.1 CDS yggX NC_013008.1 3904810 3905085 D hypothetical protein 3904810..3905085 Escherichia coli O157:H7 str. TW14359 8218500 YP_003079753.1 CDS mltC NC_013008.1 3905150 3906229 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3905150..3906229 Escherichia coli O157:H7 str. TW14359 8218501 YP_003079754.1 CDS nupG NC_013008.1 3906431 3907687 D nucleoside transporter 3906431..3907687 Escherichia coli O157:H7 str. TW14359 8218502 YP_003079755.1 CDS speC NC_013008.1 3907737 3909872 R ornithine decarboxylase complement(3907737..3909872) Escherichia coli O157:H7 str. TW14359 8218503 YP_003079756.1 CDS yqgA NC_013008.1 3910270 3910977 D inner membrane protein 3910270..3910977 Escherichia coli O157:H7 str. TW14359 8218504 YP_003079757.1 CDS ECSP_3940 NC_013008.1 3911356 3912621 D pathogenicity island integrase 3911356..3912621 Escherichia coli O157:H7 str. TW14359 8218506 YP_003079758.1 CDS ECSP_3941 NC_013008.1 3912738 3913523 R hypothetical protein complement(3912738..3913523) Escherichia coli O157:H7 str. TW14359 8218507 YP_003079759.1 CDS ECSP_3942 NC_013008.1 3913612 3914286 D hypothetical protein 3913612..3914286 Escherichia coli O157:H7 str. TW14359 8218508 YP_003079760.1 CDS ECSP_3943 NC_013008.1 3914283 3914630 D hypothetical protein 3914283..3914630 Escherichia coli O157:H7 str. TW14359 8218509 YP_003079761.1 CDS ECSP_3944 NC_013008.1 3914650 3915852 D hypothetical protein 3914650..3915852 Escherichia coli O157:H7 str. TW14359 8218510 YP_003079762.1 CDS ECSP_3945 NC_013008.1 3915899 3916843 R hypothetical protein complement(3915899..3916843) Escherichia coli O157:H7 str. TW14359 8218511 YP_003079763.1 CDS ECSP_3946 NC_013008.1 3916952 3917500 R PagC-like membrane protein complement(3916952..3917500) Escherichia coli O157:H7 str. TW14359 8218512 YP_003079764.1 CDS ECSP_3947 NC_013008.1 3918073 3918273 R hypothetical protein complement(3918073..3918273) Escherichia coli O157:H7 str. TW14359 8218513 YP_003079765.1 CDS ECSP_3948 NC_013008.1 3918559 3919113 R hypothetical protein complement(3918559..3919113) Escherichia coli O157:H7 str. TW14359 8218514 YP_003079766.1 CDS ECSP_3949 NC_013008.1 3918802 3919692 D transposase 3918802..3919692 Escherichia coli O157:H7 str. TW14359 8218515 YP_003079767.1 CDS ECSP_3950 NC_013008.1 3920166 3920336 D hypothetical protein 3920166..3920336 Escherichia coli O157:H7 str. TW14359 8218516 YP_003079768.1 CDS espL2 NC_013008.1 3920480 3922129 D non-LEE-encoded type III effector 3920480..3922129 Escherichia coli O157:H7 str. TW14359 8218517 YP_003079769.1 CDS ECSP_3952 NC_013008.1 3922320 3922496 D hypothetical protein 3922320..3922496 Escherichia coli O157:H7 str. TW14359 8218518 YP_003079770.1 CDS nleB2 NC_013008.1 3922737 3923726 D non-LEE-encoded type III effector 3922737..3923726 Escherichia coli O157:H7 str. TW14359 8218519 YP_003079771.1 CDS nleE NC_013008.1 3923775 3924449 D non-LEE-encoded type III effector 3923775..3924449 Escherichia coli O157:H7 str. TW14359 8218520 YP_003079772.1 CDS ECSP_3955 NC_013008.1 3924827 3925672 D transposase 3924827..3925672 Escherichia coli O157:H7 str. TW14359 8218521 YP_003079773.1 CDS ECSP_3958 NC_013008.1 3928498 3929388 R transposase complement(3928498..3929388) Escherichia coli O157:H7 str. TW14359 8218524 YP_003079774.1 CDS ECSP_3959 NC_013008.1 3929385 3929711 R transposase complement(3929385..3929711) Escherichia coli O157:H7 str. TW14359 8218525 YP_003079775.1 CDS ECSP_3960 NC_013008.1 3929902 3930249 D transposase 3929902..3930249 Escherichia coli O157:H7 str. TW14359 8218526 YP_003079776.1 CDS ECSP_3961 NC_013008.1 3930299 3931837 D transposase, ISEc8 3930299..3931837 Escherichia coli O157:H7 str. TW14359 8218527 YP_003079777.1 CDS ECSP_3962 NC_013008.1 3932060 3932410 D hypothetical protein 3932060..3932410 Escherichia coli O157:H7 str. TW14359 8218528 YP_003079778.1 CDS ECSP_3963 NC_013008.1 3932623 3934026 D hypothetical protein 3932623..3934026 Escherichia coli O157:H7 str. TW14359 8218529 YP_003079779.1 CDS ECSP_3964 NC_013008.1 3934118 3934288 D transposase 3934118..3934288 Escherichia coli O157:H7 str. TW14359 8218530 YP_003079780.1 CDS ECSP_3965 NC_013008.1 3934345 3934689 D transposase 3934345..3934689 Escherichia coli O157:H7 str. TW14359 8218531 YP_003079781.1 CDS ECSP_3966 NC_013008.1 3934532 3935848 R phosphate/sulfate permease complement(3934532..3935848) Escherichia coli O157:H7 str. TW14359 8218532 YP_003079782.1 CDS gsp NC_013008.1 3936140 3937999 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3936140..3937999) Escherichia coli O157:H7 str. TW14359 8218533 YP_003079783.1 CDS yghU NC_013008.1 3938204 3939070 D YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 3938204..3939070 Escherichia coli O157:H7 str. TW14359 8218534 YP_003079784.1 CDS hybG NC_013008.1 3939193 3939441 R hydrogenase 2 accessory protein HypG complement(3939193..3939441) Escherichia coli O157:H7 str. TW14359 8218535 YP_003079785.1 CDS hybF NC_013008.1 3939454 3939795 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3939454..3939795) Escherichia coli O157:H7 str. TW14359 8218536 YP_003079786.1 CDS hybE NC_013008.1 3939788 3940276 R hydrogenase 2-specific chaperone complement(3939788..3940276) Escherichia coli O157:H7 str. TW14359 8218537 YP_003079787.1 CDS hybD NC_013008.1 3940269 3940763 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3940269..3940763) Escherichia coli O157:H7 str. TW14359 8218538 YP_003079788.1 CDS hybC NC_013008.1 3940763 3942466 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3940763..3942466) Escherichia coli O157:H7 str. TW14359 8218539 YP_003079789.1 CDS hybB NC_013008.1 3942463 3943641 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3942463..3943641) Escherichia coli O157:H7 str. TW14359 8218540 YP_003079790.1 CDS hybA NC_013008.1 3943631 3944617 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3943631..3944617) Escherichia coli O157:H7 str. TW14359 8218541 YP_003079791.1 CDS hybO NC_013008.1 3944620 3945738 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3944620..3945738) Escherichia coli O157:H7 str. TW14359 8218542 YP_003079792.1 CDS yghW NC_013008.1 3945927 3946214 R hypothetical protein complement(3945927..3946214) Escherichia coli O157:H7 str. TW14359 8218543 YP_003079793.1 CDS yghX NC_013008.1 3946333 3947220 R hydrolase complement(3946333..3947220) Escherichia coli O157:H7 str. TW14359 8218544 YP_003079794.1 CDS yghZ NC_013008.1 3947377 3948417 D aldo/keto reductase 3947377..3948417 Escherichia coli O157:H7 str. TW14359 8218545 YP_003079795.1 CDS yqhA NC_013008.1 3948457 3948951 R hypothetical protein complement(3948457..3948951) Escherichia coli O157:H7 str. TW14359 8218546 YP_003079796.1 CDS yghA NC_013008.1 3949142 3950026 D oxidoreductase 3949142..3950026 Escherichia coli O157:H7 str. TW14359 8218547 YP_003079797.1 CDS exbD NC_013008.1 3950298 3950723 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3950298..3950723) Escherichia coli O157:H7 str. TW14359 8218548 YP_003079798.1 CDS exbB NC_013008.1 3950730 3951464 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3950730..3951464) Escherichia coli O157:H7 str. TW14359 8218549 YP_003079799.1 CDS metC NC_013008.1 3951716 3952903 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3951716..3952903 Escherichia coli O157:H7 str. TW14359 8218550 YP_003079800.1 CDS yghB NC_013008.1 3953043 3953702 D hypothetical protein 3953043..3953702 Escherichia coli O157:H7 str. TW14359 8218551 YP_003079801.1 CDS yqhC NC_013008.1 3953742 3954698 R DNA-binding transcriptional regulator complement(3953742..3954698) Escherichia coli O157:H7 str. TW14359 8218552 YP_003079802.1 CDS yqhD NC_013008.1 3954835 3955998 D NADP-dependent alcohol dehydrogenase 3954835..3955998 Escherichia coli O157:H7 str. TW14359 8218553 YP_003079803.1 CDS dkgA NC_013008.1 3956103 3956930 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3956103..3956930 Escherichia coli O157:H7 str. TW14359 8218554 YP_003079804.1 CDS ECSP_3989 NC_013008.1 3957130 3957405 D hypothetical protein 3957130..3957405 Escherichia coli O157:H7 str. TW14359 8218555 YP_003079805.1 CDS yqhG NC_013008.1 3957399 3958052 D hypothetical protein 3957399..3958052 Escherichia coli O157:H7 str. TW14359 8218556 YP_003079806.1 CDS yqhH NC_013008.1 3958101 3958358 D outer membrane lipoprotein 3958101..3958358 Escherichia coli O157:H7 str. TW14359 8218557 YP_003079807.1 CDS ygiQ NC_013008.1 3958401 3960620 R hypothetical protein complement(3958401..3960620) Escherichia coli O157:H7 str. TW14359 8218558 YP_003079808.1 CDS sufI NC_013008.1 3960731 3962143 R repressor protein for FtsI complement(3960731..3962143) Escherichia coli O157:H7 str. TW14359 8218559 YP_003079809.1 CDS plsC NC_013008.1 3962218 3962955 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3962218..3962955) Escherichia coli O157:H7 str. TW14359 8218560 YP_003079810.1 CDS parC NC_013008.1 3963189 3965447 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3963189..3965447) Escherichia coli O157:H7 str. TW14359 8218561 YP_003079811.1 CDS ygiS NC_013008.1 3965585 3967192 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; binding protein complement(3965585..3967192) Escherichia coli O157:H7 str. TW14359 8218562 YP_003079812.1 CDS ygiV NC_013008.1 3967301 3967783 R transcriptional regulator complement(3967301..3967783) Escherichia coli O157:H7 str. TW14359 8218563 YP_003079813.1 CDS ygiW NC_013008.1 3967836 3968228 R hypothetical protein complement(3967836..3968228) Escherichia coli O157:H7 str. TW14359 8218564 YP_003079814.1 CDS qseB NC_013008.1 3968380 3969039 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3968380..3969039 Escherichia coli O157:H7 str. TW14359 8218565 YP_003079815.1 CDS qseC NC_013008.1 3969036 3970385 D sensor protein QseC 3969036..3970385 Escherichia coli O157:H7 str. TW14359 8218566 YP_003079816.1 CDS mdaB NC_013008.1 3970495 3971076 D NADPH quinone reductase 3970495..3971076 Escherichia coli O157:H7 str. TW14359 8218567 YP_003079817.1 CDS ygiN NC_013008.1 3971107 3971421 D quinol monooxygenase 3971107..3971421 Escherichia coli O157:H7 str. TW14359 8218568 YP_003079818.1 CDS ECSP_4003 NC_013008.1 3971466 3972353 R hypothetical protein complement(3971466..3972353) Escherichia coli O157:H7 str. TW14359 8218569 YP_003079819.1 CDS ECSP_4004 NC_013008.1 3972350 3973297 R iron compound-binding protein of ABC transporter family complement(3972350..3973297) Escherichia coli O157:H7 str. TW14359 8218570 YP_003079820.1 CDS ECSP_4005 NC_013008.1 3973308 3974357 R iron compound permease of ABC transporter family complement(3973308..3974357) Escherichia coli O157:H7 str. TW14359 8218571 YP_003079821.1 CDS ECSP_4006 NC_013008.1 3974354 3975337 R iron compound permease of ABC transporter family complement(3974354..3975337) Escherichia coli O157:H7 str. TW14359 8218572 YP_003079822.1 CDS ECSP_4007 NC_013008.1 3975334 3976143 R ATP-binding protein of ABC transporter family complement(3975334..3976143) Escherichia coli O157:H7 str. TW14359 8218573 YP_003079823.1 CDS ECSP_4008 NC_013008.1 3976517 3978658 D iron compound receptor 3976517..3978658 Escherichia coli O157:H7 str. TW14359 8218574 YP_003079824.1 CDS parE NC_013008.1 3978722 3980614 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3978722..3980614) Escherichia coli O157:H7 str. TW14359 8218575 YP_003079825.1 CDS yqiA NC_013008.1 3980643 3981224 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(3980643..3981224) Escherichia coli O157:H7 str. TW14359 8218576 YP_003079826.1 CDS cpdA NC_013008.1 3981224 3982051 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3981224..3982051) Escherichia coli O157:H7 str. TW14359 8218577 YP_003079827.1 CDS yqiB NC_013008.1 3982076 3982498 R hypothetical protein complement(3982076..3982498) Escherichia coli O157:H7 str. TW14359 8218578 YP_003079828.1 CDS nudF NC_013008.1 3982499 3983128 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase complement(3982499..3983128) Escherichia coli O157:H7 str. TW14359 8218579 YP_003079829.1 CDS tolC NC_013008.1 3983333 3984814 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3983333..3984814 Escherichia coli O157:H7 str. TW14359 8218580 YP_003079830.1 CDS ygiB NC_013008.1 3984962 3985633 D hypothetical protein 3984962..3985633 Escherichia coli O157:H7 str. TW14359 8218581 YP_003079831.1 CDS ygiC NC_013008.1 3985639 3986799 D hypothetical protein 3985639..3986799 Escherichia coli O157:H7 str. TW14359 8218582 YP_003079832.1 CDS ygiD NC_013008.1 3986837 3987625 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3986837..3987625) Escherichia coli O157:H7 str. TW14359 8218583 YP_003079833.1 CDS zupT NC_013008.1 3987768 3988541 D zinc transporter ZupT 3987768..3988541 Escherichia coli O157:H7 str. TW14359 8218584 YP_003079834.1 CDS ECSP_4019 NC_013008.1 3988599 3988769 R hypothetical protein complement(3988599..3988769) Escherichia coli O157:H7 str. TW14359 8218585 YP_003079835.1 CDS ribB NC_013008.1 3989031 3989684 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3989031..3989684) Escherichia coli O157:H7 str. TW14359 8218586 YP_003079836.1 CDS yqiC NC_013008.1 3990058 3990357 D hypothetical protein 3990058..3990357 Escherichia coli O157:H7 str. TW14359 8218587 YP_003079837.1 CDS glgS NC_013008.1 3990392 3990592 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3990392..3990592) Escherichia coli O157:H7 str. TW14359 8218588 YP_003079838.1 CDS yqiJ NC_013008.1 3990861 3991475 D inner membrane protein 3990861..3991475 Escherichia coli O157:H7 str. TW14359 8218589 YP_003079839.1 CDS yqiK NC_013008.1 3991517 3993178 D hypothetical protein 3991517..3993178 Escherichia coli O157:H7 str. TW14359 8218590 YP_003079840.1 CDS rfaE NC_013008.1 3993972 3995405 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3993972..3995405) Escherichia coli O157:H7 str. TW14359 8218591 YP_003079841.1 CDS glnE NC_013008.1 3995453 3998293 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3995453..3998293) Escherichia coli O157:H7 str. TW14359 8218592 YP_003079842.1 CDS ygiF NC_013008.1 3998316 3999617 R adenylate cyclase complement(3998316..3999617) Escherichia coli O157:H7 str. TW14359 8218593 YP_003079843.1 CDS htrG NC_013008.1 3999859 4000479 D signal transduction protein 3999859..4000479 Escherichia coli O157:H7 str. TW14359 8218594 YP_003079844.1 CDS cca NC_013008.1 4000543 4001781 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 4000543..4001781 Escherichia coli O157:H7 str. TW14359 8218595 YP_003079845.1 CDS bacA NC_013008.1 4001962 4002783 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(4001962..4002783) Escherichia coli O157:H7 str. TW14359 8218596 YP_003079846.1 CDS folB NC_013008.1 4002874 4003242 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(4002874..4003242) Escherichia coli O157:H7 str. TW14359 8218597 YP_003079847.1 CDS ygiH NC_013008.1 4003348 4003965 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 4003348..4003965 Escherichia coli O157:H7 str. TW14359 8218598 YP_003079848.1 CDS ygiP NC_013008.1 4003978 4004910 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(4003978..4004910) Escherichia coli O157:H7 str. TW14359 8218599 YP_003079849.1 CDS ttdA NC_013008.1 4005117 4006028 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 4005117..4006028 Escherichia coli O157:H7 str. TW14359 8218600 YP_003079850.1 CDS ttdB NC_013008.1 4006025 4006630 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 4006025..4006630 Escherichia coli O157:H7 str. TW14359 8218601 YP_003079851.1 CDS ygjE NC_013008.1 4006679 4008142 D tartrate:succinate antiporter 4006679..4008142 Escherichia coli O157:H7 str. TW14359 8218602 YP_003079852.1 CDS ygjD NC_013008.1 4008185 4009198 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(4008185..4009198) Escherichia coli O157:H7 str. TW14359 8218603 YP_003079853.1 CDS rpsU NC_013008.1 4009436 4009651 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 4009436..4009651 Escherichia coli O157:H7 str. TW14359 8218604 YP_003079854.1 CDS dnaG NC_013008.1 4009762 4011507 D synthesizes RNA primers at the replication forks; DNA primase 4009762..4011507 Escherichia coli O157:H7 str. TW14359 8218605 YP_003079855.1 CDS ECSP_4040 NC_013008.1 4011521 4011643 D hypothetical protein 4011521..4011643 Escherichia coli O157:H7 str. TW14359 8218606 YP_003079856.1 CDS rpoD NC_013008.1 4011702 4013543 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 4011702..4013543 Escherichia coli O157:H7 str. TW14359 8218607 YP_003079857.1 CDS mug NC_013008.1 4013622 4014128 R G/U mismatch-specific DNA glycosylase complement(4013622..4014128) Escherichia coli O157:H7 str. TW14359 8218608 YP_003079858.1 CDS yqjH NC_013008.1 4014382 4015146 R siderophore interacting protein complement(4014382..4015146) Escherichia coli O157:H7 str. TW14359 8218610 YP_003079859.1 CDS yqjI NC_013008.1 4015434 4016057 D transcriptional regulator 4015434..4016057 Escherichia coli O157:H7 str. TW14359 8218611 YP_003079860.1 CDS aer NC_013008.1 4016211 4017731 R fused signal transducer for aerotaxis sensory component, methyl accepting chemotaxis component complement(4016211..4017731) Escherichia coli O157:H7 str. TW14359 8218612 YP_003079861.1 CDS ygjG NC_013008.1 4018149 4019528 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 4018149..4019528 Escherichia coli O157:H7 str. TW14359 8218613 YP_003079862.1 CDS ygjH NC_013008.1 4019570 4019902 R hypothetical protein complement(4019570..4019902) Escherichia coli O157:H7 str. TW14359 8218614 YP_003079863.1 CDS ebgR NC_013008.1 4020121 4021104 D DNA-binding transcriptional repressor EbgR 4020121..4021104 Escherichia coli O157:H7 str. TW14359 8218615 YP_003079864.1 CDS ebgA NC_013008.1 4021288 4024380 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 4021288..4024380 Escherichia coli O157:H7 str. TW14359 8218616 YP_003079865.1 CDS ebgC NC_013008.1 4024377 4024826 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 4024377..4024826 Escherichia coli O157:H7 str. TW14359 8218617 YP_003079866.1 CDS ygjI NC_013008.1 4024889 4026322 D transporter 4024889..4026322 Escherichia coli O157:H7 str. TW14359 8218618 YP_003079867.1 CDS ygjJ NC_013008.1 4026456 4027526 D hypothetical protein 4026456..4027526 Escherichia coli O157:H7 str. TW14359 8218619 YP_003079868.1 CDS ygjK NC_013008.1 4027543 4029894 D glycosyl hydrolase 4027543..4029894 Escherichia coli O157:H7 str. TW14359 8218620 YP_003079869.1 CDS fadH NC_013008.1 4030420 4032438 D 2,4-dienoyl-CoA reductase 4030420..4032438 Escherichia coli O157:H7 str. TW14359 8218621 YP_003079870.1 CDS ygjM NC_013008.1 4032483 4032899 R DNA-binding transcriptional regulator complement(4032483..4032899) Escherichia coli O157:H7 str. TW14359 8218622 YP_003079871.1 CDS ygjN NC_013008.1 4032896 4033210 R hypothetical protein complement(4032896..4033210) Escherichia coli O157:H7 str. TW14359 8218623 YP_003079872.1 CDS ygjO NC_013008.1 4033494 4034630 R methyltransferase small domain-containing protein complement(4033494..4034630) Escherichia coli O157:H7 str. TW14359 8218624 YP_003079873.1 CDS ygjP NC_013008.1 4034715 4035218 D metal dependent hydrolase 4034715..4035218 Escherichia coli O157:H7 str. TW14359 8218625 YP_003079874.1 CDS ygjQ NC_013008.1 4035295 4035987 D thioredoxin-like protein 4035295..4035987 Escherichia coli O157:H7 str. TW14359 8218626 YP_003079875.1 CDS ygjR NC_013008.1 4036066 4037052 D NAD(P)-binding dehydrogenase 4036066..4037052 Escherichia coli O157:H7 str. TW14359 8218627 YP_003079876.1 CDS alx NC_013008.1 4037336 4038301 D inner membrane protein, part of terminus 4037336..4038301 Escherichia coli O157:H7 str. TW14359 8218628 YP_003079877.1 CDS sstT NC_013008.1 4038700 4039944 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 4038700..4039944 Escherichia coli O157:H7 str. TW14359 8218629 YP_003079878.1 CDS ygjV NC_013008.1 4039949 4040500 R hypothetical protein complement(4039949..4040500) Escherichia coli O157:H7 str. TW14359 8218630 YP_003079879.1 CDS uxaA NC_013008.1 4040583 4042070 R altronate hydrolase complement(4040583..4042070) Escherichia coli O157:H7 str. TW14359 8218631 YP_003079880.1 CDS uxaC NC_013008.1 4042085 4043497 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(4042085..4043497) Escherichia coli O157:H7 str. TW14359 8218632 YP_003079881.1 CDS exuT NC_013008.1 4043860 4045278 D hexuronate transporter 4043860..4045278 Escherichia coli O157:H7 str. TW14359 8218633 YP_003079882.1 CDS exuR NC_013008.1 4045408 4046184 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 4045408..4046184 Escherichia coli O157:H7 str. TW14359 8218634 YP_003079883.1 CDS yqjA NC_013008.1 4046529 4047191 D hypothetical protein 4046529..4047191 Escherichia coli O157:H7 str. TW14359 8218635 YP_003079884.1 CDS yqjB NC_013008.1 4047195 4047578 D hypothetical protein 4047195..4047578 Escherichia coli O157:H7 str. TW14359 8218636 YP_003079885.1 CDS yqjC NC_013008.1 4047725 4048093 D hypothetical protein 4047725..4048093 Escherichia coli O157:H7 str. TW14359 8218637 YP_003079886.1 CDS yqjD NC_013008.1 4048131 4048436 D hypothetical protein 4048131..4048436 Escherichia coli O157:H7 str. TW14359 8218638 YP_003079887.1 CDS yqjE NC_013008.1 4048439 4048843 D hypothetical protein 4048439..4048843 Escherichia coli O157:H7 str. TW14359 8218639 YP_003079888.1 CDS yqjK NC_013008.1 4048833 4049132 D hypothetical protein 4048833..4049132 Escherichia coli O157:H7 str. TW14359 8218640 YP_003079889.1 CDS yqjF NC_013008.1 4049318 4049710 D quinol oxidase subunit 4049318..4049710 Escherichia coli O157:H7 str. TW14359 8218641 YP_003079890.1 CDS yqjG NC_013008.1 4049780 4050766 D S-transferase 4049780..4050766 Escherichia coli O157:H7 str. TW14359 8218642 YP_003079891.1 CDS yhaH NC_013008.1 4051058 4051423 D inner membrane protein 4051058..4051423 Escherichia coli O157:H7 str. TW14359 8218643 YP_003079892.1 CDS yhaI NC_013008.1 4051664 4052020 D inner membrane protein 4051664..4052020 Escherichia coli O157:H7 str. TW14359 8218644 YP_003079893.1 CDS yhaJ NC_013008.1 4052071 4052967 R DNA-binding transcriptional regulator complement(4052071..4052967) Escherichia coli O157:H7 str. TW14359 8218645 YP_003079894.1 CDS yhaK NC_013008.1 4053072 4053773 D pirin-related protein 4053072..4053773 Escherichia coli O157:H7 str. TW14359 8218646 YP_003079895.1 CDS yhaL NC_013008.1 4053796 4053960 D hypothetical protein 4053796..4053960 Escherichia coli O157:H7 str. TW14359 8218647 YP_003079896.1 CDS yhaM NC_013008.1 4054094 4055404 R hypothetical protein complement(4054094..4055404) Escherichia coli O157:H7 str. TW14359 8218648 YP_003079897.1 CDS yhaO NC_013008.1 4055432 4056763 R transporter complement(4055432..4056763) Escherichia coli O157:H7 str. TW14359 8218649 YP_003079898.1 CDS tdcG NC_013008.1 4057038 4058402 R L-serine dehydratase 3 complement(4057038..4058402) Escherichia coli O157:H7 str. TW14359 8218650 YP_003079899.1 CDS tdcF NC_013008.1 4058474 4058863 R hypothetical protein complement(4058474..4058863) Escherichia coli O157:H7 str. TW14359 8218651 YP_003079900.1 CDS tdcE NC_013008.1 4058877 4061171 R pyruvate formate-lyase 4/2-ketobutyrate formate-lyase complement(4058877..4061171) Escherichia coli O157:H7 str. TW14359 8218652 YP_003079901.1 CDS tdcD NC_013008.1 4061205 4062413 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(4061205..4062413) Escherichia coli O157:H7 str. TW14359 8218653 YP_003079902.1 CDS tdcC NC_013008.1 4062439 4063770 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(4062439..4063770) Escherichia coli O157:H7 str. TW14359 8218654 YP_003079903.1 CDS tdcB NC_013008.1 4063792 4064781 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(4063792..4064781) Escherichia coli O157:H7 str. TW14359 8218655 YP_003079904.1 CDS tdcA NC_013008.1 4064880 4065818 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(4064880..4065818) Escherichia coli O157:H7 str. TW14359 8218656 YP_003079905.1 CDS tdcR NC_013008.1 4066133 4066351 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 4066133..4066351 Escherichia coli O157:H7 str. TW14359 8218657 YP_003079906.1 CDS yhaB NC_013008.1 4066607 4067146 D hypothetical protein 4066607..4067146 Escherichia coli O157:H7 str. TW14359 8218658 YP_003079907.1 CDS yhaC NC_013008.1 4067168 4068355 D hypothetical protein 4067168..4068355 Escherichia coli O157:H7 str. TW14359 8218659 YP_003079908.1 CDS ECSP_4094 NC_013008.1 4068416 4068571 D hypothetical protein 4068416..4068571 Escherichia coli O157:H7 str. TW14359 8218660 YP_003079909.1 CDS garK NC_013008.1 4068984 4070129 R glycerate kinase I complement(4068984..4070129) Escherichia coli O157:H7 str. TW14359 8218661 YP_003079910.1 CDS garR NC_013008.1 4070226 4071110 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(4070226..4071110) Escherichia coli O157:H7 str. TW14359 8218662 YP_003079911.1 CDS garL NC_013008.1 4071146 4071916 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(4071146..4071916) Escherichia coli O157:H7 str. TW14359 8218663 YP_003079912.1 CDS garP NC_013008.1 4071932 4073266 R (D)-galactarate transporter complement(4071932..4073266) Escherichia coli O157:H7 str. TW14359 8218664 YP_003079913.1 CDS garD NC_013008.1 4073641 4075212 D (D)-galactarate dehydrogenase 4073641..4075212 Escherichia coli O157:H7 str. TW14359 8218665 YP_003079914.1 CDS sohA NC_013008.1 4075361 4075696 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 4075361..4075696 Escherichia coli O157:H7 str. TW14359 8218666 YP_003079915.1 CDS yhaV NC_013008.1 4075696 4076160 D hypothetical protein 4075696..4076160 Escherichia coli O157:H7 str. TW14359 8218667 YP_003079916.1 CDS agaR NC_013008.1 4076215 4077024 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(4076215..4077024) Escherichia coli O157:H7 str. TW14359 8218668 YP_003079917.1 CDS kbaZ NC_013008.1 4077273 4078553 D tagatose-biphosphate aldolase 1, kbaZ subunit 4077273..4078553 Escherichia coli O157:H7 str. TW14359 8218669 YP_003079918.1 CDS agaV NC_013008.1 4078576 4079049 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4078576..4079049 Escherichia coli O157:H7 str. TW14359 8218670 YP_003079919.1 CDS agaW NC_013008.1 4079060 4079839 D phosphotransferase system enzyme subunit 4079060..4079839 Escherichia coli O157:H7 str. TW14359 8218671 YP_003079920.1 CDS agaE NC_013008.1 4079829 4080707 D phosphotransferase system enzyme subunit 4079829..4080707 Escherichia coli O157:H7 str. TW14359 8218672 YP_003079921.1 CDS agaF NC_013008.1 4080725 4081159 D phosphotransferase system enzyme subunit 4080725..4081159 Escherichia coli O157:H7 str. TW14359 8218673 YP_003079922.1 CDS agaA NC_013008.1 4081156 4082289 D N-acetylgalactosamine-6-phosphate deacetylase 4081156..4082289 Escherichia coli O157:H7 str. TW14359 8218674 YP_003079923.1 CDS ECSP_4109 NC_013008.1 4082407 4082541 D hypothetical protein 4082407..4082541 Escherichia coli O157:H7 str. TW14359 8218675 YP_003079924.1 CDS agaS NC_013008.1 4082640 4083794 D tagatose-6-phosphate ketose/aldose isomerase 4082640..4083794 Escherichia coli O157:H7 str. TW14359 8218676 YP_003079925.1 CDS kbaY NC_013008.1 4083807 4084667 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 4083807..4084667 Escherichia coli O157:H7 str. TW14359 8218677 YP_003079926.1 CDS agaB NC_013008.1 4084834 4085310 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4084834..4085310 Escherichia coli O157:H7 str. TW14359 8218678 YP_003079927.1 CDS agaC NC_013008.1 4085577 4086152 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 4085577..4086152 Escherichia coli O157:H7 str. TW14359 8218679 YP_003079928.1 CDS agaD NC_013008.1 4086142 4086933 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 4086142..4086933 Escherichia coli O157:H7 str. TW14359 8218680 YP_003079929.1 CDS yraH NC_013008.1 4088090 4088674 D fimbrial-like adhesin protein 4088090..4088674 Escherichia coli O157:H7 str. TW14359 8218682 YP_003079930.1 CDS yraI NC_013008.1 4088754 4089449 D periplasmic pilin chaperone 4088754..4089449 Escherichia coli O157:H7 str. TW14359 8218683 YP_003079931.1 CDS yraJ NC_013008.1 4089478 4091994 D outer membrane protein 4089478..4091994 Escherichia coli O157:H7 str. TW14359 8218684 YP_003079932.1 CDS ECSP_4119 NC_013008.1 4091834 4092412 D hypothetical protein 4091834..4092412 Escherichia coli O157:H7 str. TW14359 8218685 YP_003079933.1 CDS ECSP_4120 NC_013008.1 4092388 4092738 D fimbrial protein 4092388..4092738 Escherichia coli O157:H7 str. TW14359 8218686 YP_003079934.1 CDS yraL NC_013008.1 4092781 4093641 R methyltransferase complement(4092781..4093641) Escherichia coli O157:H7 str. TW14359 8218687 YP_003079935.1 CDS yraM NC_013008.1 4093706 4095742 D lipoprotein 4093706..4095742 Escherichia coli O157:H7 str. TW14359 8218688 YP_003079936.1 CDS yraN NC_013008.1 4095700 4096095 D hypothetical protein 4095700..4096095 Escherichia coli O157:H7 str. TW14359 8218689 YP_003079937.1 CDS diaA NC_013008.1 4096115 4096705 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 4096115..4096705 Escherichia coli O157:H7 str. TW14359 8218690 YP_003079938.1 CDS yraP NC_013008.1 4096715 4097290 D hypothetical protein 4096715..4097290 Escherichia coli O157:H7 str. TW14359 8218691 YP_003079939.1 CDS yraQ NC_013008.1 4097404 4098444 R permease complement(4097404..4098444) Escherichia coli O157:H7 str. TW14359 8218692 YP_003079940.1 CDS yraR NC_013008.1 4098517 4099152 R nucleoside-diphosphate-sugar epimerase complement(4098517..4099152) Escherichia coli O157:H7 str. TW14359 8218693 YP_003079941.1 CDS yhbO NC_013008.1 4099280 4099798 D intracellular protease 4099280..4099798 Escherichia coli O157:H7 str. TW14359 8218694 YP_003079942.1 CDS yhbP NC_013008.1 4099778 4100221 R hypothetical protein complement(4099778..4100221) Escherichia coli O157:H7 str. TW14359 8218695 YP_003079943.1 CDS yhbQ NC_013008.1 4100272 4100574 D GIY-YIG nuclease superfamily protein 4100272..4100574 Escherichia coli O157:H7 str. TW14359 8218696 YP_003079944.1 CDS yhbS NC_013008.1 4100561 4101064 R acyl-CoA N-acyltransferase domain-containing acyltransferase complement(4100561..4101064) Escherichia coli O157:H7 str. TW14359 8218697 YP_003079945.1 CDS yhbT NC_013008.1 4101058 4101582 R lipid carrier protein complement(4101058..4101582) Escherichia coli O157:H7 str. TW14359 8218698 YP_003079946.1 CDS yhbU NC_013008.1 4101791 4102786 D collagenase-like peptidase 4101791..4102786 Escherichia coli O157:H7 str. TW14359 8218699 YP_003079947.1 CDS yhbV NC_013008.1 4102795 4103673 D protease 4102795..4103673 Escherichia coli O157:H7 str. TW14359 8218700 YP_003079948.1 CDS yhbW NC_013008.1 4103754 4104761 D hypothetical protein 4103754..4104761 Escherichia coli O157:H7 str. TW14359 8218701 YP_003079949.1 CDS mtr NC_013008.1 4104878 4106122 R tryptophan transporter of high affinity; tryptophan permease complement(4104878..4106122) Escherichia coli O157:H7 str. TW14359 8218702 YP_003079950.1 CDS deaD NC_013008.1 4106276 4108165 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(4106276..4108165) Escherichia coli O157:H7 str. TW14359 8218703 YP_003079951.1 CDS nlpI NC_013008.1 4108345 4109229 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(4108345..4109229) Escherichia coli O157:H7 str. TW14359 8218704 YP_003079952.1 CDS pnp NC_013008.1 4109338 4111473 R polynucleotide phosphorylase complement(4109338..4111473) Escherichia coli O157:H7 str. TW14359 8218705 YP_003079953.1 CDS rpsO NC_013008.1 4111720 4111989 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(4111720..4111989) Escherichia coli O157:H7 str. TW14359 8218706 YP_003079954.1 CDS truB NC_013008.1 4112138 4113082 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(4112138..4113082) Escherichia coli O157:H7 str. TW14359 8218707 YP_003079955.1 CDS rbfA NC_013008.1 4113082 4113483 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(4113082..4113483) Escherichia coli O157:H7 str. TW14359 8218708 YP_003079956.1 CDS infB NC_013008.1 4113648 4116320 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(4113648..4116320) Escherichia coli O157:H7 str. TW14359 8218709 YP_003079957.1 CDS nusA NC_013008.1 4116345 4117832 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(4116345..4117832) Escherichia coli O157:H7 str. TW14359 8218710 YP_003079958.1 CDS yhbC NC_013008.1 4117860 4118312 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(4117860..4118312) Escherichia coli O157:H7 str. TW14359 8218711 YP_003079959.1 CDS argG NC_013008.1 4118943 4120286 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 4118943..4120286 Escherichia coli O157:H7 str. TW14359 8218713 YP_003079960.1 CDS yhbX NC_013008.1 4120294 4121919 R hydrolase complement(4120294..4121919) Escherichia coli O157:H7 str. TW14359 8218714 YP_003079961.1 CDS secG NC_013008.1 4122479 4122811 R preprotein translocase subunit SecG complement(4122479..4122811) Escherichia coli O157:H7 str. TW14359 8218716 YP_003079962.1 CDS glmM NC_013008.1 4123039 4124376 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(4123039..4124376) Escherichia coli O157:H7 str. TW14359 8218717 YP_003079963.1 CDS folP NC_013008.1 4124369 4125217 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(4124369..4125217) Escherichia coli O157:H7 str. TW14359 8218718 YP_003079964.1 CDS hflB NC_013008.1 4125307 4127241 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(4125307..4127241) Escherichia coli O157:H7 str. TW14359 8218719 YP_003079965.1 CDS rrmJ NC_013008.1 4127341 4127970 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase complement(4127341..4127970) Escherichia coli O157:H7 str. TW14359 8218720 YP_003079966.1 CDS yhbY NC_013008.1 4128096 4128389 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 4128096..4128389 Escherichia coli O157:H7 str. TW14359 8218721 YP_003079967.1 CDS greA NC_013008.1 4128545 4129021 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(4128545..4129021) Escherichia coli O157:H7 str. TW14359 8218722 YP_003079968.1 CDS dacB NC_013008.1 4129269 4130702 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 4129269..4130702 Escherichia coli O157:H7 str. TW14359 8218723 YP_003079969.1 CDS obgE NC_013008.1 4130742 4131914 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(4130742..4131914) Escherichia coli O157:H7 str. TW14359 8218724 YP_003079970.1 CDS yhbE NC_013008.1 4131930 4132895 R hypothetical protein complement(4131930..4132895) Escherichia coli O157:H7 str. TW14359 8218725 YP_003079971.1 CDS rpmA NC_013008.1 4133022 4133279 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(4133022..4133279) Escherichia coli O157:H7 str. TW14359 8218726 YP_003079972.1 CDS rplU NC_013008.1 4133300 4133611 R 50S ribosomal protein L21 complement(4133300..4133611) Escherichia coli O157:H7 str. TW14359 8218727 YP_003079973.1 CDS ispB NC_013008.1 4133870 4134841 D octaprenyl diphosphate synthase 4133870..4134841 Escherichia coli O157:H7 str. TW14359 8218728 YP_003079974.1 CDS sfsB NC_013008.1 4135070 4135348 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 4135070..4135348 Escherichia coli O157:H7 str. TW14359 8218729 YP_003079975.1 CDS murA NC_013008.1 4135396 4136655 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(4135396..4136655) Escherichia coli O157:H7 str. TW14359 8218730 YP_003079976.1 CDS yrbA NC_013008.1 4136710 4136964 R DNA-binding transcriptional regulator complement(4136710..4136964) Escherichia coli O157:H7 str. TW14359 8218731 YP_003079977.1 CDS yrbB NC_013008.1 4137124 4137417 R hypothetical protein complement(4137124..4137417) Escherichia coli O157:H7 str. TW14359 8218732 YP_003079978.1 CDS yrbC NC_013008.1 4137417 4138052 R ABC-type organic solvent transporter complement(4137417..4138052) Escherichia coli O157:H7 str. TW14359 8218733 YP_003079979.1 CDS yrbD NC_013008.1 4138071 4138622 R ABC-type organic solvent transporter complement(4138071..4138622) Escherichia coli O157:H7 str. TW14359 8218734 YP_003079980.1 CDS yrbE NC_013008.1 4138627 4139409 R toluene ABC transporter membrane protein complement(4138627..4139409) Escherichia coli O157:H7 str. TW14359 8218735 YP_003079981.1 CDS yrbF NC_013008.1 4139417 4140226 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF complement(4139417..4140226) Escherichia coli O157:H7 str. TW14359 8218736 YP_003079982.1 CDS yrbG NC_013008.1 4140436 4141413 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 4140436..4141413 Escherichia coli O157:H7 str. TW14359 8218737 YP_003079983.1 CDS kdsD NC_013008.1 4141427 4142413 D D-arabinose 5-phosphate isomerase 4141427..4142413 Escherichia coli O157:H7 str. TW14359 8218738 YP_003079984.1 CDS kdsC NC_013008.1 4142434 4143000 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 4142434..4143000 Escherichia coli O157:H7 str. TW14359 8218739 YP_003079985.1 CDS yrbK NC_013008.1 4142997 4143572 D hypothetical protein 4142997..4143572 Escherichia coli O157:H7 str. TW14359 8218740 YP_003079986.1 CDS yhbN NC_013008.1 4143541 4144098 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 4143541..4144098 Escherichia coli O157:H7 str. TW14359 8218741 YP_003079987.1 CDS yhbG NC_013008.1 4144105 4144830 D ABC transporter ATP-binding protein YhbG 4144105..4144830 Escherichia coli O157:H7 str. TW14359 8218742 YP_003079988.1 CDS rpoN NC_013008.1 4144878 4146311 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 4144878..4146311 Escherichia coli O157:H7 str. TW14359 8218743 YP_003079989.1 CDS hpf NC_013008.1 4146334 4146621 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 4146334..4146621 Escherichia coli O157:H7 str. TW14359 8218744 YP_003079990.1 CDS ptsN NC_013008.1 4146739 4147230 D PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 4146739..4147230 Escherichia coli O157:H7 str. TW14359 8218745 YP_003079991.1 CDS yhbJ NC_013008.1 4147276 4148130 D hypothetical protein 4147276..4148130 Escherichia coli O157:H7 str. TW14359 8218746 YP_003079992.1 CDS npr NC_013008.1 4148127 4148399 D phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 4148127..4148399 Escherichia coli O157:H7 str. TW14359 8218747 YP_003079993.1 CDS yrbL NC_013008.1 4148613 4149245 D hypothetical protein 4148613..4149245 Escherichia coli O157:H7 str. TW14359 8218748 YP_003079994.1 CDS mtgA NC_013008.1 4149242 4149970 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(4149242..4149970) Escherichia coli O157:H7 str. TW14359 8218749 YP_003079995.1 CDS elbB NC_013008.1 4149967 4150620 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(4149967..4150620) Escherichia coli O157:H7 str. TW14359 8218750 YP_003079996.1 CDS arcB NC_013008.1 4150850 4153186 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(4150850..4153186) Escherichia coli O157:H7 str. TW14359 8218751 YP_003079997.1 CDS yhcC NC_013008.1 4153282 4154211 R Fe-S oxidoreductase complement(4153282..4154211) Escherichia coli O157:H7 str. TW14359 8218752 YP_003079998.1 CDS gltB NC_013008.1 4154792 4159345 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 4154792..4159345 Escherichia coli O157:H7 str. TW14359 8218753 YP_003079999.1 CDS gltD NC_013008.1 4159358 4160776 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 4159358..4160776 Escherichia coli O157:H7 str. TW14359 8218754 YP_003080000.1 CDS yhcG NC_013008.1 4160960 4162009 D hypothetical protein 4160960..4162009 Escherichia coli O157:H7 str. TW14359 8218755 YP_003080001.1 CDS yhcH NC_013008.1 4162069 4162533 R hypothetical protein complement(4162069..4162533) Escherichia coli O157:H7 str. TW14359 8218756 YP_003080002.1 CDS nanK NC_013008.1 4162530 4163405 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(4162530..4163405) Escherichia coli O157:H7 str. TW14359 8218757 YP_003080003.1 CDS nanE NC_013008.1 4163402 4164091 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(4163402..4164091) Escherichia coli O157:H7 str. TW14359 8218758 YP_003080004.1 CDS nanT NC_013008.1 4164139 4165629 R sialic acid transporter complement(4164139..4165629) Escherichia coli O157:H7 str. TW14359 8218759 YP_003080005.1 CDS nanA NC_013008.1 4165738 4166631 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(4165738..4166631) Escherichia coli O157:H7 str. TW14359 8218760 YP_003080006.1 CDS nanR NC_013008.1 4166753 4167544 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(4166753..4167544) Escherichia coli O157:H7 str. TW14359 8218761 YP_003080007.1 CDS dcuD NC_013008.1 4167924 4169288 D YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; cryptic C4-dicarboxylate transporter DcuD 4167924..4169288 Escherichia coli O157:H7 str. TW14359 8218762 YP_003080008.1 CDS sspB NC_013008.1 4169323 4169820 R ClpXP protease specificity-enhancing factor complement(4169323..4169820) Escherichia coli O157:H7 str. TW14359 8218763 YP_003080009.1 CDS sspA NC_013008.1 4169826 4170464 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(4169826..4170464) Escherichia coli O157:H7 str. TW14359 8218764 YP_003080010.1 CDS rpsI NC_013008.1 4170859 4171251 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(4170859..4171251) Escherichia coli O157:H7 str. TW14359 8218765 YP_003080011.1 CDS rplM NC_013008.1 4171267 4171695 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(4171267..4171695) Escherichia coli O157:H7 str. TW14359 8218766 YP_003080012.1 CDS yhcM NC_013008.1 4171914 4173041 R hypothetical protein complement(4171914..4173041) Escherichia coli O157:H7 str. TW14359 8218767 YP_003080013.1 CDS yhcB NC_013008.1 4173235 4173633 D cytochrome d ubiquinol oxidase subunit III 4173235..4173633 Escherichia coli O157:H7 str. TW14359 8218768 YP_003080014.1 CDS degQ NC_013008.1 4173787 4175154 D serine endoprotease 4173787..4175154 Escherichia coli O157:H7 str. TW14359 8218769 YP_003080015.1 CDS degS NC_013008.1 4175244 4176311 D serine endoprotease 4175244..4176311 Escherichia coli O157:H7 str. TW14359 8218770 YP_003080016.1 CDS mdh NC_013008.1 4176375 4177313 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(4176375..4177313) Escherichia coli O157:H7 str. TW14359 8218771 YP_003080017.1 CDS argR NC_013008.1 4177748 4178218 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 4177748..4178218 Escherichia coli O157:H7 str. TW14359 8218772 YP_003080018.1 CDS yhcN NC_013008.1 4178583 4178846 D hypothetical protein 4178583..4178846 Escherichia coli O157:H7 str. TW14359 8218773 YP_003080019.1 CDS yhcO NC_013008.1 4178902 4179174 R barnase inhibitor complement(4178902..4179174) Escherichia coli O157:H7 str. TW14359 8218774 YP_003080020.1 CDS aaeB NC_013008.1 4179266 4181233 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(4179266..4181233) Escherichia coli O157:H7 str. TW14359 8218775 YP_003080021.1 CDS aaeA NC_013008.1 4181239 4182168 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(4181239..4182168) Escherichia coli O157:H7 str. TW14359 8218776 YP_003080022.1 CDS aaeX NC_013008.1 4182176 4182379 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(4182176..4182379) Escherichia coli O157:H7 str. TW14359 8218777 YP_003080023.1 CDS aaeR NC_013008.1 4182562 4183491 D DNA-binding transcriptional regulator 4182562..4183491 Escherichia coli O157:H7 str. TW14359 8218778 YP_003080024.1 CDS tldD NC_013008.1 4183625 4185070 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(4183625..4185070) Escherichia coli O157:H7 str. TW14359 8218779 YP_003080025.1 CDS yhdP NC_013008.1 4185226 4189026 R hypothetical protein complement(4185226..4189026) Escherichia coli O157:H7 str. TW14359 8218780 YP_003080026.1 CDS rng NC_013008.1 4189094 4190563 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(4189094..4190563) Escherichia coli O157:H7 str. TW14359 8218781 YP_003080027.1 CDS yhdE NC_013008.1 4190553 4191146 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(4190553..4191146) Escherichia coli O157:H7 str. TW14359 8218782 YP_003080028.1 CDS mreD NC_013008.1 4191155 4191643 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(4191155..4191643) Escherichia coli O157:H7 str. TW14359 8218783 YP_003080029.1 CDS mreC NC_013008.1 4191643 4192746 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(4191643..4192746) Escherichia coli O157:H7 str. TW14359 8218784 YP_003080030.1 CDS mreB NC_013008.1 4192812 4193855 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(4192812..4193855) Escherichia coli O157:H7 str. TW14359 8218785 YP_003080031.1 CDS yhdA NC_013008.1 4194160 4196100 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(4194160..4196100) Escherichia coli O157:H7 str. TW14359 8218786 YP_003080032.1 CDS yhdH NC_013008.1 4196252 4197226 D oxidoreductase 4196252..4197226 Escherichia coli O157:H7 str. TW14359 8218787 YP_003080033.1 CDS ECSP_4222 NC_013008.1 4197263 4197427 D initiation of DNA replication 4197263..4197427 Escherichia coli O157:H7 str. TW14359 8218788 YP_003080034.1 CDS ECSP_4223 NC_013008.1 4197512 4197631 D hypothetical protein 4197512..4197631 Escherichia coli O157:H7 str. TW14359 8218789 YP_003080035.1 CDS accB NC_013008.1 4198204 4198674 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 4198204..4198674 Escherichia coli O157:H7 str. TW14359 8218790 YP_003080036.1 CDS accC NC_013008.1 4198685 4200034 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 4198685..4200034 Escherichia coli O157:H7 str. TW14359 8218791 YP_003080037.1 CDS yhdT NC_013008.1 4200143 4200385 D hypothetical protein 4200143..4200385 Escherichia coli O157:H7 str. TW14359 8218792 YP_003080038.1 CDS panF NC_013008.1 4200375 4201826 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 4200375..4201826 Escherichia coli O157:H7 str. TW14359 8218793 YP_003080039.1 CDS prmA NC_013008.1 4201838 4202719 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 4201838..4202719 Escherichia coli O157:H7 str. TW14359 8218794 YP_003080040.1 CDS dusB NC_013008.1 4203048 4204013 D tRNA-dihydrouridine synthase B 4203048..4204013 Escherichia coli O157:H7 str. TW14359 8218795 YP_003080041.1 CDS fis NC_013008.1 4204039 4204335 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 4204039..4204335 Escherichia coli O157:H7 str. TW14359 8218796 YP_003080042.1 CDS yhdJ NC_013008.1 4204420 4205304 D methyltransferase 4204420..4205304 Escherichia coli O157:H7 str. TW14359 8218797 YP_003080043.1 CDS yhdU NC_013008.1 4205388 4205567 D hypothetical protein 4205388..4205567 Escherichia coli O157:H7 str. TW14359 8218798 YP_003080044.1 CDS envR NC_013008.1 4205570 4206232 R DNA-binding transcriptional regulator EnvR complement(4205570..4206232) Escherichia coli O157:H7 str. TW14359 8218799 YP_003080045.1 CDS acrE NC_013008.1 4206631 4207788 D cytoplasmic membrane lipoprotein 4206631..4207788 Escherichia coli O157:H7 str. TW14359 8218800 YP_003080046.1 CDS yhdV NC_013008.1 4211202 4211423 D outer membrane protein 4211202..4211423 Escherichia coli O157:H7 str. TW14359 8218802 YP_003080047.1 CDS yhdW NC_013008.1 4211854 4212879 D periplasmic-binding component of an ABC superfamily amino acid transporter 4211854..4212879 Escherichia coli O157:H7 str. TW14359 8218803 YP_003080048.1 CDS yhdX NC_013008.1 4212947 4214128 D amino-acid ABC transporter membrane protein 4212947..4214128 Escherichia coli O157:H7 str. TW14359 8218804 YP_003080049.1 CDS yhdY NC_013008.1 4214138 4215226 D amino-acid ABC transporter membrane protein 4214138..4215226 Escherichia coli O157:H7 str. TW14359 8218805 YP_003080050.1 CDS ECSP_4240 NC_013008.1 4215252 4215578 D transposase 4215252..4215578 Escherichia coli O157:H7 str. TW14359 8218806 YP_003080051.1 CDS ECSP_4241 NC_013008.1 4215575 4216465 D transposase 4215575..4216465 Escherichia coli O157:H7 str. TW14359 8218807 YP_003080052.1 CDS yhdZ NC_013008.1 4216562 4217320 D amino-acid transporter subunit, ATP-binding protein of ABC superfamily 4216562..4217320 Escherichia coli O157:H7 str. TW14359 8218808 YP_003080053.1 CDS yrdA NC_013008.1 4223042 4223923 D hypothetical protein 4223042..4223923 Escherichia coli O157:H7 str. TW14359 8218816 YP_003080054.1 CDS yrdB NC_013008.1 4223899 4224156 R hypothetical protein complement(4223899..4224156) Escherichia coli O157:H7 str. TW14359 8218817 YP_003080055.1 CDS aroE NC_013008.1 4224153 4224971 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(4224153..4224971) Escherichia coli O157:H7 str. TW14359 8218818 YP_003080056.1 CDS yrdC NC_013008.1 4224976 4225548 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(4224976..4225548) Escherichia coli O157:H7 str. TW14359 8218819 YP_003080057.1 CDS yrdD NC_013008.1 4225553 4226095 R DNA topoisomerase complement(4225553..4226095) Escherichia coli O157:H7 str. TW14359 8218820 YP_003080058.1 CDS smg NC_013008.1 4226124 4226597 R hypothetical protein complement(4226124..4226597) Escherichia coli O157:H7 str. TW14359 8218821 YP_003080059.1 CDS smf NC_013008.1 4226569 4227693 R DNA protecting protein DprA complement(4226569..4227693) Escherichia coli O157:H7 str. TW14359 8218822 YP_003080060.1 CDS def NC_013008.1 4227823 4228332 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4227823..4228332 Escherichia coli O157:H7 str. TW14359 8218823 YP_003080061.1 CDS fmt NC_013008.1 4228347 4229294 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 4228347..4229294 Escherichia coli O157:H7 str. TW14359 8218824 YP_003080062.1 CDS rsmB NC_013008.1 4229340 4230629 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 4229340..4230629 Escherichia coli O157:H7 str. TW14359 8218825 YP_003080063.1 CDS trkA NC_013008.1 4230651 4232027 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 4230651..4232027 Escherichia coli O157:H7 str. TW14359 8218826 YP_003080064.1 CDS mscL NC_013008.1 4232157 4232567 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 4232157..4232567 Escherichia coli O157:H7 str. TW14359 8218827 YP_003080065.1 CDS yhdL NC_013008.1 4232564 4232782 R hypothetical protein complement(4232564..4232782) Escherichia coli O157:H7 str. TW14359 8218828 YP_003080066.1 CDS zntR NC_013008.1 4232838 4233263 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(4232838..4233263) Escherichia coli O157:H7 str. TW14359 8218829 YP_003080067.1 CDS yhdN NC_013008.1 4233274 4233642 R hypothetical protein complement(4233274..4233642) Escherichia coli O157:H7 str. TW14359 8218830 YP_003080068.1 CDS rplQ NC_013008.1 4233749 4234132 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(4233749..4234132) Escherichia coli O157:H7 str. TW14359 8218831 YP_003080069.1 CDS rpoA NC_013008.1 4234173 4235162 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(4234173..4235162) Escherichia coli O157:H7 str. TW14359 8218832 YP_003080070.1 CDS rpsD NC_013008.1 4235188 4235808 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(4235188..4235808) Escherichia coli O157:H7 str. TW14359 8218833 YP_003080071.1 CDS rpsK NC_013008.1 4235842 4236231 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(4235842..4236231) Escherichia coli O157:H7 str. TW14359 8218834 YP_003080072.1 CDS rpsM NC_013008.1 4236248 4236604 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(4236248..4236604) Escherichia coli O157:H7 str. TW14359 8218835 YP_003080073.1 CDS rpmJ NC_013008.1 4236751 4236867 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(4236751..4236867) Escherichia coli O157:H7 str. TW14359 8218836 YP_003080074.1 CDS secY NC_013008.1 4236899 4238230 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(4236899..4238230) Escherichia coli O157:H7 str. TW14359 8218837 YP_003080075.1 CDS rplO NC_013008.1 4238238 4238672 R late assembly protein; 50S ribosomal protein L15 complement(4238238..4238672) Escherichia coli O157:H7 str. TW14359 8218838 YP_003080076.1 CDS rpmD NC_013008.1 4238676 4238855 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(4238676..4238855) Escherichia coli O157:H7 str. TW14359 8218839 YP_003080077.1 CDS rpsE NC_013008.1 4238859 4239362 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(4238859..4239362) Escherichia coli O157:H7 str. TW14359 8218840 YP_003080078.1 CDS rplR NC_013008.1 4239377 4239730 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(4239377..4239730) Escherichia coli O157:H7 str. TW14359 8218841 YP_003080079.1 CDS rplF NC_013008.1 4239740 4240273 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(4239740..4240273) Escherichia coli O157:H7 str. TW14359 8218842 YP_003080080.1 CDS rpsH NC_013008.1 4240286 4240678 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(4240286..4240678) Escherichia coli O157:H7 str. TW14359 8218843 YP_003080081.1 CDS rpsN NC_013008.1 4240712 4241017 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(4240712..4241017) Escherichia coli O157:H7 str. TW14359 8218844 YP_003080082.1 CDS rplE NC_013008.1 4241032 4241571 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(4241032..4241571) Escherichia coli O157:H7 str. TW14359 8218845 YP_003080083.1 CDS rplX NC_013008.1 4241586 4241900 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(4241586..4241900) Escherichia coli O157:H7 str. TW14359 8218846 YP_003080084.1 CDS rplN NC_013008.1 4241911 4242282 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(4241911..4242282) Escherichia coli O157:H7 str. TW14359 8218847 YP_003080085.1 CDS rpsQ NC_013008.1 4242447 4242701 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(4242447..4242701) Escherichia coli O157:H7 str. TW14359 8218848 YP_003080086.1 CDS rpmC NC_013008.1 4242701 4242892 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(4242701..4242892) Escherichia coli O157:H7 str. TW14359 8218849 YP_003080087.1 CDS rplP NC_013008.1 4242892 4243302 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(4242892..4243302) Escherichia coli O157:H7 str. TW14359 8218850 YP_003080088.1 CDS rpsC NC_013008.1 4243315 4244016 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(4243315..4244016) Escherichia coli O157:H7 str. TW14359 8218851 YP_003080089.1 CDS rplV NC_013008.1 4244034 4244366 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(4244034..4244366) Escherichia coli O157:H7 str. TW14359 8218852 YP_003080090.1 CDS rpsS NC_013008.1 4244381 4244659 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(4244381..4244659) Escherichia coli O157:H7 str. TW14359 8218853 YP_003080091.1 CDS rplB NC_013008.1 4244676 4245497 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(4244676..4245497) Escherichia coli O157:H7 str. TW14359 8218854 YP_003080092.1 CDS rplW NC_013008.1 4245515 4245817 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(4245515..4245817) Escherichia coli O157:H7 str. TW14359 8218855 YP_003080093.1 CDS rplD NC_013008.1 4245814 4246419 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(4245814..4246419) Escherichia coli O157:H7 str. TW14359 8218856 YP_003080094.1 CDS rplC NC_013008.1 4246430 4247059 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(4246430..4247059) Escherichia coli O157:H7 str. TW14359 8218857 YP_003080095.1 CDS rpsJ NC_013008.1 4247092 4247403 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(4247092..4247403) Escherichia coli O157:H7 str. TW14359 8218858 YP_003080096.1 CDS hopD NC_013008.1 4247782 4248249 D leader peptidase 4247782..4248249 Escherichia coli O157:H7 str. TW14359 8218859 YP_003080097.1 CDS bfr NC_013008.1 4248246 4248722 R iron storage protein; bacterioferritin complement(4248246..4248722) Escherichia coli O157:H7 str. TW14359 8218860 YP_003080098.1 CDS bfd NC_013008.1 4248795 4248989 R bacterioferritin-associated ferredoxin complement(4248795..4248989) Escherichia coli O157:H7 str. TW14359 8218861 YP_003080099.1 CDS tufA NC_013008.1 4249172 4250356 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(4249172..4250356) Escherichia coli O157:H7 str. TW14359 8218862 YP_003080100.1 CDS fusA NC_013008.1 4250427 4252541 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(4250427..4252541) Escherichia coli O157:H7 str. TW14359 8218863 YP_003080101.1 CDS rpsG NC_013008.1 4252638 4253108 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(4252638..4253108) Escherichia coli O157:H7 str. TW14359 8218864 YP_003080102.1 CDS rpsL NC_013008.1 4253205 4253579 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(4253205..4253579) Escherichia coli O157:H7 str. TW14359 8218865 YP_003080103.1 CDS yheL NC_013008.1 4253705 4253992 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(4253705..4253992) Escherichia coli O157:H7 str. TW14359 8218866 YP_003080104.1 CDS yheM NC_013008.1 4254000 4254359 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(4254000..4254359) Escherichia coli O157:H7 str. TW14359 8218867 YP_003080105.1 CDS yheN NC_013008.1 4254359 4254745 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(4254359..4254745) Escherichia coli O157:H7 str. TW14359 8218868 YP_003080106.1 CDS yheO NC_013008.1 4254745 4255467 R DNA-binding transcriptional regulator complement(4254745..4255467) Escherichia coli O157:H7 str. TW14359 8218869 YP_003080107.1 CDS fkpA NC_013008.1 4255634 4256446 R rotamase; FKBP-type peptidylprolyl isomerase complement(4255634..4256446) Escherichia coli O157:H7 str. TW14359 8218870 YP_003080108.1 CDS slyX NC_013008.1 4256667 4256885 D hypothetical protein 4256667..4256885 Escherichia coli O157:H7 str. TW14359 8218871 YP_003080109.1 CDS slyD NC_013008.1 4256934 4257524 R rotamase; FKBP-type peptidylprolyl isomerase complement(4256934..4257524) Escherichia coli O157:H7 str. TW14359 8218872 YP_003080110.1 CDS yheV NC_013008.1 4257619 4257819 R hypothetical protein complement(4257619..4257819) Escherichia coli O157:H7 str. TW14359 8218873 YP_003080111.1 CDS kefB NC_013008.1 4257856 4259634 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(4257856..4259634) Escherichia coli O157:H7 str. TW14359 8218874 YP_003080112.1 CDS kefG NC_013008.1 4259634 4260188 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(4259634..4260188) Escherichia coli O157:H7 str. TW14359 8218875 YP_003080113.1 CDS yheS NC_013008.1 4260316 4262229 D ABC transporter ATP-binding protein 4260316..4262229 Escherichia coli O157:H7 str. TW14359 8218876 YP_003080114.1 CDS yheT NC_013008.1 4262229 4263251 D hydrolase 4262229..4263251 Escherichia coli O157:H7 str. TW14359 8218877 YP_003080115.1 CDS yheU NC_013008.1 4263245 4263463 D hypothetical protein 4263245..4263463 Escherichia coli O157:H7 str. TW14359 8218878 YP_003080116.1 CDS prkB NC_013008.1 4263517 4264386 D phosphoribulokinase 4263517..4264386 Escherichia coli O157:H7 str. TW14359 8218879 YP_003080117.1 CDS yhfA NC_013008.1 4264441 4264845 R hypothetical protein complement(4264441..4264845) Escherichia coli O157:H7 str. TW14359 8218880 YP_003080118.1 CDS crp NC_013008.1 4265147 4265779 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 4265147..4265779 Escherichia coli O157:H7 str. TW14359 8218881 YP_003080119.1 CDS yhfK NC_013008.1 4265818 4267920 D hypothetical protein 4265818..4267920 Escherichia coli O157:H7 str. TW14359 8218882 YP_003080120.1 CDS argD NC_013008.1 4267987 4269207 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(4267987..4269207) Escherichia coli O157:H7 str. TW14359 8218883 YP_003080121.1 CDS pabA NC_013008.1 4269293 4269856 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(4269293..4269856) Escherichia coli O157:H7 str. TW14359 8218884 YP_003080122.1 CDS fic NC_013008.1 4269888 4270490 R cell filamentation protein Fic complement(4269888..4270490) Escherichia coli O157:H7 str. TW14359 8218885 YP_003080123.1 CDS yhfG NC_013008.1 4270480 4270647 R hypothetical protein complement(4270480..4270647) Escherichia coli O157:H7 str. TW14359 8218886 YP_003080124.1 CDS ppiA NC_013008.1 4270752 4271324 R peptidyl-prolyl cis-trans isomerase A complement(4270752..4271324) Escherichia coli O157:H7 str. TW14359 8218887 YP_003080125.1 CDS tsgA NC_013008.1 4271595 4272776 D hypothetical protein 4271595..4272776 Escherichia coli O157:H7 str. TW14359 8218888 YP_003080126.1 CDS nirB NC_013008.1 4273038 4275581 D nitrite reductase, large subunit, NAD(P)H-binding 4273038..4275581 Escherichia coli O157:H7 str. TW14359 8218889 YP_003080127.1 CDS nirD NC_013008.1 4275578 4275904 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 4275578..4275904 Escherichia coli O157:H7 str. TW14359 8218890 YP_003080128.1 CDS nirC NC_013008.1 4276030 4276836 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 4276030..4276836 Escherichia coli O157:H7 str. TW14359 8218891 YP_003080129.1 CDS cysG NC_013008.1 4276855 4278228 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 4276855..4278228 Escherichia coli O157:H7 str. TW14359 8218892 YP_003080130.1 CDS yhfL NC_013008.1 4278483 4278650 D hypothetical protein 4278483..4278650 Escherichia coli O157:H7 str. TW14359 8218893 YP_003080131.1 CDS frlA NC_013008.1 4278946 4280283 D inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; fructoselysine transporter 4278946..4280283 Escherichia coli O157:H7 str. TW14359 8218894 YP_003080132.1 CDS frlB NC_013008.1 4280304 4281326 D catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 4280304..4281326 Escherichia coli O157:H7 str. TW14359 8218895 YP_003080133.1 CDS frlC NC_013008.1 4281377 4282204 D YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 4281377..4282204 Escherichia coli O157:H7 str. TW14359 8218896 YP_003080134.1 CDS frlR NC_013008.1 4283089 4283820 D may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 4283089..4283820 Escherichia coli O157:H7 str. TW14359 8218898 YP_003080135.1 CDS trpS NC_013008.1 4283951 4284955 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(4283951..4284955) Escherichia coli O157:H7 str. TW14359 8218899 YP_003080136.1 CDS gph NC_013008.1 4284948 4285706 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(4284948..4285706) Escherichia coli O157:H7 str. TW14359 8218900 YP_003080137.1 CDS rpe NC_013008.1 4285699 4286376 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(4285699..4286376) Escherichia coli O157:H7 str. TW14359 8218901 YP_003080138.1 CDS dam NC_013008.1 4286394 4287230 R DNA adenine methylase complement(4286394..4287230) Escherichia coli O157:H7 str. TW14359 8218902 YP_003080139.1 CDS damX NC_013008.1 4287337 4288623 R hypothetical protein complement(4287337..4288623) Escherichia coli O157:H7 str. TW14359 8218903 YP_003080140.1 CDS aroB NC_013008.1 4288715 4289803 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(4288715..4289803) Escherichia coli O157:H7 str. TW14359 8218904 YP_003080141.1 CDS aroK NC_013008.1 4289860 4290381 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(4289860..4290381) Escherichia coli O157:H7 str. TW14359 8218905 YP_003080142.1 CDS hofQ NC_013008.1 4290782 4292020 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(4290782..4292020) Escherichia coli O157:H7 str. TW14359 8218906 YP_003080143.1 CDS yrfA NC_013008.1 4291932 4292336 R hypothetical protein complement(4291932..4292336) Escherichia coli O157:H7 str. TW14359 8218907 YP_003080144.1 CDS yrfB NC_013008.1 4292326 4292766 R hypothetical protein complement(4292326..4292766) Escherichia coli O157:H7 str. TW14359 8218908 YP_003080145.1 CDS yrfC NC_013008.1 4292750 4293289 R fimbrial assembly protein complement(4292750..4293289) Escherichia coli O157:H7 str. TW14359 8218909 YP_003080146.1 CDS yrfD NC_013008.1 4293273 4294067 R pilus assembly protein complement(4293273..4294067) Escherichia coli O157:H7 str. TW14359 8218910 YP_003080147.1 CDS mrcA NC_013008.1 4294187 4296739 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 4294187..4296739 Escherichia coli O157:H7 str. TW14359 8218911 YP_003080148.1 CDS nudE NC_013008.1 4296904 4297464 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(4296904..4297464) Escherichia coli O157:H7 str. TW14359 8218912 YP_003080149.1 CDS yrfF NC_013008.1 4297784 4299919 D inner membrane protein 4297784..4299919 Escherichia coli O157:H7 str. TW14359 8218913 YP_003080150.1 CDS yrfG NC_013008.1 4299984 4300652 D hydrolase 4299984..4300652 Escherichia coli O157:H7 str. TW14359 8218914 YP_003080151.1 CDS hslR NC_013008.1 4300663 4301064 D ribosome-associated heat shock protein Hsp15 4300663..4301064 Escherichia coli O157:H7 str. TW14359 8218915 YP_003080152.1 CDS hslO NC_013008.1 4301089 4301967 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 4301089..4301967 Escherichia coli O157:H7 str. TW14359 8218916 YP_003080153.1 CDS yhgE NC_013008.1 4302030 4303754 R inner membrane protein complement(4302030..4303754) Escherichia coli O157:H7 str. TW14359 8218917 YP_003080154.1 CDS ECSP_4352 NC_013008.1 4303830 4303961 R hypothetical protein complement(4303830..4303961) Escherichia coli O157:H7 str. TW14359 8218918 YP_003080155.1 CDS pck NC_013008.1 4304133 4305755 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 4304133..4305755 Escherichia coli O157:H7 str. TW14359 8218919 YP_003080156.1 CDS envZ NC_013008.1 4305831 4307183 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(4305831..4307183) Escherichia coli O157:H7 str. TW14359 8218920 YP_003080157.1 CDS ompR NC_013008.1 4307180 4307899 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(4307180..4307899) Escherichia coli O157:H7 str. TW14359 8218921 YP_003080158.1 CDS greB NC_013008.1 4308127 4308603 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 4308127..4308603 Escherichia coli O157:H7 str. TW14359 8218922 YP_003080159.1 CDS yhgF NC_013008.1 4308700 4311021 D transcriptional accessory protein 4308700..4311021 Escherichia coli O157:H7 str. TW14359 8218923 YP_003080160.1 CDS feoA NC_013008.1 4311459 4311686 D ferrous iron transport protein A 4311459..4311686 Escherichia coli O157:H7 str. TW14359 8218924 YP_003080161.1 CDS feoB NC_013008.1 4311703 4314024 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 4311703..4314024 Escherichia coli O157:H7 str. TW14359 8218925 YP_003080162.1 CDS yhgG NC_013008.1 4314024 4314260 D DNA-binding transcriptional regulator 4314024..4314260 Escherichia coli O157:H7 str. TW14359 8218926 YP_003080163.1 CDS yhgA NC_013008.1 4314463 4315341 D hypothetical protein 4314463..4315341 Escherichia coli O157:H7 str. TW14359 8218927 YP_003080164.1 CDS bioH NC_013008.1 4315368 4316138 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(4315368..4316138) Escherichia coli O157:H7 str. TW14359 8218928 YP_003080165.1 CDS gntX NC_013008.1 4316176 4316859 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 4316176..4316859 Escherichia coli O157:H7 str. TW14359 8218929 YP_003080166.1 CDS gntY NC_013008.1 4316918 4317493 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 4316918..4317493 Escherichia coli O157:H7 str. TW14359 8218930 YP_003080167.1 CDS gntT NC_013008.1 4317854 4319170 D gluconate transporter, high-affinity GNT I system 4317854..4319170 Escherichia coli O157:H7 str. TW14359 8218931 YP_003080168.1 CDS malQ NC_013008.1 4319215 4321299 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(4319215..4321299) Escherichia coli O157:H7 str. TW14359 8218932 YP_003080169.1 CDS malP NC_013008.1 4321309 4323702 R maltodextrin phosphorylase complement(4321309..4323702) Escherichia coli O157:H7 str. TW14359 8218933 YP_003080170.1 CDS ECSP_4368 NC_013008.1 4323962 4324063 R hypothetical protein complement(4323962..4324063) Escherichia coli O157:H7 str. TW14359 8218934 YP_003080171.1 CDS malT NC_013008.1 4324314 4327019 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 4324314..4327019 Escherichia coli O157:H7 str. TW14359 8218935 YP_003080172.1 CDS ECSP_4370 NC_013008.1 4327080 4327364 D hypothetical protein 4327080..4327364 Escherichia coli O157:H7 str. TW14359 8218936 YP_003080173.1 CDS ECSP_4371 NC_013008.1 4327355 4327840 D hypothetical protein 4327355..4327840 Escherichia coli O157:H7 str. TW14359 8218937 YP_003080174.1 CDS rtcA NC_013008.1 4327890 4328918 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(4327890..4328918) Escherichia coli O157:H7 str. TW14359 8218938 YP_003080175.1 CDS rtcB NC_013008.1 4328922 4330148 R hypothetical protein complement(4328922..4330148) Escherichia coli O157:H7 str. TW14359 8218939 YP_003080176.1 CDS rtcR NC_013008.1 4330336 4331934 D sigma 54-dependent transcriptional regulator of rtcBA expression 4330336..4331934 Escherichia coli O157:H7 str. TW14359 8218940 YP_003080177.1 CDS glpR NC_013008.1 4331916 4332674 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(4331916..4332674) Escherichia coli O157:H7 str. TW14359 8218941 YP_003080178.1 CDS glpG NC_013008.1 4332691 4333521 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(4332691..4333521) Escherichia coli O157:H7 str. TW14359 8218942 YP_003080179.1 CDS glpE NC_013008.1 4333566 4333892 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(4333566..4333892) Escherichia coli O157:H7 str. TW14359 8218943 YP_003080180.1 CDS glpD NC_013008.1 4334082 4335587 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 4334082..4335587 Escherichia coli O157:H7 str. TW14359 8218944 YP_003080181.1 CDS ECSP_4379 NC_013008.1 4335802 4336401 R hypothetical protein complement(4335802..4336401) Escherichia coli O157:H7 str. TW14359 8218945 YP_003080182.1 CDS ECSP_4380 NC_013008.1 4336404 4337396 R hypothetical protein complement(4336404..4337396) Escherichia coli O157:H7 str. TW14359 8218946 YP_003080183.1 CDS yzgL NC_013008.1 4337422 4338930 R periplasmic-binding component of an ABC superfamily transporter complement(4337422..4338930) Escherichia coli O157:H7 str. TW14359 8218947 YP_003080184.1 CDS glgP NC_013008.1 4339055 4341502 R glycogen phosphorylase complement(4339055..4341502) Escherichia coli O157:H7 str. TW14359 8218948 YP_003080185.1 CDS glgA NC_013008.1 4341521 4342954 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(4341521..4342954) Escherichia coli O157:H7 str. TW14359 8218949 YP_003080186.1 CDS glgC NC_013008.1 4342954 4344249 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(4342954..4344249) Escherichia coli O157:H7 str. TW14359 8218950 YP_003080187.1 CDS glgX NC_013008.1 4344267 4346240 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme complement(4344267..4346240) Escherichia coli O157:H7 str. TW14359 8218951 YP_003080188.1 CDS glgB NC_013008.1 4346237 4348423 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme complement(4346237..4348423) Escherichia coli O157:H7 str. TW14359 8218952 YP_003080189.1 CDS asd NC_013008.1 4348696 4349799 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(4348696..4349799) Escherichia coli O157:H7 str. TW14359 8218953 YP_003080190.1 CDS yhgN NC_013008.1 4349991 4350584 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4349991..4350584 Escherichia coli O157:H7 str. TW14359 8218954 YP_003080191.1 CDS ECSP_4389 NC_013008.1 4350630 4351832 R DNA processing protein complement(4350630..4351832) Escherichia coli O157:H7 str. TW14359 8218955 YP_003080192.1 CDS gntU NC_013008.1 4354096 4355436 R low affinity gluconate transporter complement(4354096..4355436) Escherichia coli O157:H7 str. TW14359 8218957 YP_003080193.1 CDS gntK NC_013008.1 4355440 4355967 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 complement(4355440..4355967) Escherichia coli O157:H7 str. TW14359 8218958 YP_003080194.1 CDS gntR NC_013008.1 4356106 4357101 R DNA-binding transcriptional repressor complement(4356106..4357101) Escherichia coli O157:H7 str. TW14359 8218959 YP_003080195.1 CDS yhhW NC_013008.1 4357325 4358020 R hypothetical protein complement(4357325..4358020) Escherichia coli O157:H7 str. TW14359 8218960 YP_003080196.1 CDS yhhX NC_013008.1 4358143 4359180 R dehydrogenase complement(4358143..4359180) Escherichia coli O157:H7 str. TW14359 8218961 YP_003080197.1 CDS yhhY NC_013008.1 4359514 4360002 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 4359514..4360002 Escherichia coli O157:H7 str. TW14359 8218962 YP_003080198.1 CDS ECSP_4397 NC_013008.1 4360213 4361124 D hypothetical protein 4360213..4361124 Escherichia coli O157:H7 str. TW14359 8218963 YP_003080199.1 CDS ECSP_4398 NC_013008.1 4361073 4361489 R hypothetical protein complement(4361073..4361489) Escherichia coli O157:H7 str. TW14359 8218964 YP_003080200.1 CDS ggt NC_013008.1 4361858 4363603 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(4361858..4363603) Escherichia coli O157:H7 str. TW14359 8218965 YP_003080201.1 CDS yhhA NC_013008.1 4363723 4364163 D hypothetical protein 4363723..4364163 Escherichia coli O157:H7 str. TW14359 8218966 YP_003080202.1 CDS ugpQ NC_013008.1 4364150 4364893 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase complement(4364150..4364893) Escherichia coli O157:H7 str. TW14359 8218967 YP_003080203.1 CDS ugpC NC_013008.1 4364890 4365960 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(4364890..4365960) Escherichia coli O157:H7 str. TW14359 8218968 YP_003080204.1 CDS ugpE NC_013008.1 4365962 4366807 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(4365962..4366807) Escherichia coli O157:H7 str. TW14359 8218969 YP_003080205.1 CDS ugpA NC_013008.1 4366804 4367691 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(4366804..4367691) Escherichia coli O157:H7 str. TW14359 8218970 YP_003080206.1 CDS ugpB NC_013008.1 4367789 4369105 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(4367789..4369105) Escherichia coli O157:H7 str. TW14359 8218971 YP_003080207.1 CDS ECSP_4406 NC_013008.1 4369465 4370211 R hypothetical protein complement(4369465..4370211) Escherichia coli O157:H7 str. TW14359 8218972 YP_003080208.1 CDS livF NC_013008.1 4370330 4371043 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4370330..4371043) Escherichia coli O157:H7 str. TW14359 8218973 YP_003080209.1 CDS livG NC_013008.1 4371045 4371812 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4371045..4371812) Escherichia coli O157:H7 str. TW14359 8218974 YP_003080210.1 CDS livM NC_013008.1 4371809 4373086 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(4371809..4373086) Escherichia coli O157:H7 str. TW14359 8218975 YP_003080211.1 CDS livH NC_013008.1 4373083 4374009 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(4373083..4374009) Escherichia coli O157:H7 str. TW14359 8218976 YP_003080212.1 CDS livK NC_013008.1 4374057 4375166 R leucine ABC transporter periplasmic-binding protein complement(4374057..4375166) Escherichia coli O157:H7 str. TW14359 8218977 YP_003080213.1 CDS ECSP_4412 NC_013008.1 4375318 4375455 R hypothetical protein complement(4375318..4375455) Escherichia coli O157:H7 str. TW14359 8218978 YP_003080214.1 CDS yhhK NC_013008.1 4375590 4375973 D N-acetyltransferase 4375590..4375973 Escherichia coli O157:H7 str. TW14359 8218979 YP_003080215.1 CDS ECSP_4414 NC_013008.1 4375970 4376497 R hypothetical protein complement(4375970..4376497) Escherichia coli O157:H7 str. TW14359 8218980 YP_003080216.1 CDS ECSP_4415 NC_013008.1 4376504 4376770 R hypothetical protein complement(4376504..4376770) Escherichia coli O157:H7 str. TW14359 8218981 YP_003080217.1 CDS livJ NC_013008.1 4376920 4378023 R leucine/isoleucine/valine ABC transporter periplasmic-binding protein complement(4376920..4378023) Escherichia coli O157:H7 str. TW14359 8218982 YP_003080218.1 CDS rpoH NC_013008.1 4378294 4379148 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(4378294..4379148) Escherichia coli O157:H7 str. TW14359 8218983 YP_003080219.1 CDS ftsX NC_013008.1 4379393 4380451 R ABC transporter, membrane protein; cell division protein FtsX complement(4379393..4380451) Escherichia coli O157:H7 str. TW14359 8218984 YP_003080220.1 CDS ftsE NC_013008.1 4380444 4381112 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(4380444..4381112) Escherichia coli O157:H7 str. TW14359 8218985 YP_003080221.1 CDS ftsY NC_013008.1 4381115 4382611 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(4381115..4382611) Escherichia coli O157:H7 str. TW14359 8218986 YP_003080222.1 CDS rsmD NC_013008.1 4382761 4383357 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4382761..4383357 Escherichia coli O157:H7 str. TW14359 8218987 YP_003080223.1 CDS yhhL NC_013008.1 4383347 4383616 D hypothetical protein 4383347..4383616 Escherichia coli O157:H7 str. TW14359 8218988 YP_003080224.1 CDS yhhM NC_013008.1 4383619 4383978 R hypothetical protein complement(4383619..4383978) Escherichia coli O157:H7 str. TW14359 8218989 YP_003080225.1 CDS yhhN NC_013008.1 4384119 4384745 D hypothetical protein 4384119..4384745 Escherichia coli O157:H7 str. TW14359 8218990 YP_003080226.1 CDS zntA NC_013008.1 4384819 4387017 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4384819..4387017 Escherichia coli O157:H7 str. TW14359 8218991 YP_003080227.1 CDS sirA NC_013008.1 4387119 4387364 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(4387119..4387364) Escherichia coli O157:H7 str. TW14359 8218992 YP_003080228.1 CDS yhhQ NC_013008.1 4387585 4388250 D hypothetical protein 4387585..4388250 Escherichia coli O157:H7 str. TW14359 8218993 YP_003080229.1 CDS dcrB NC_013008.1 4388323 4388880 D hypothetical protein 4388323..4388880 Escherichia coli O157:H7 str. TW14359 8218994 YP_003080230.1 CDS yhhS NC_013008.1 4388884 4390101 R major facilitator superfamily transporter complement(4388884..4390101) Escherichia coli O157:H7 str. TW14359 8218995 YP_003080231.1 CDS yhhT NC_013008.1 4390233 4391282 D inner membrane protein 4390233..4391282 Escherichia coli O157:H7 str. TW14359 8218996 YP_003080232.1 CDS ECSP_4431 NC_013008.1 4391674 4392051 D hypothetical protein 4391674..4392051 Escherichia coli O157:H7 str. TW14359 8218997 YP_003080233.1 CDS ECSP_4432 NC_013008.1 4392120 4393178 D O-methyltransferase 4392120..4393178 Escherichia coli O157:H7 str. TW14359 8218998 YP_003080234.1 CDS ECSP_4433 NC_013008.1 4393219 4393941 D hypothetical protein 4393219..4393941 Escherichia coli O157:H7 str. TW14359 8218999 YP_003080235.1 CDS ECSP_4434 NC_013008.1 4394091 4394759 D phospholipid biosynthesis acyltransferase 4394091..4394759 Escherichia coli O157:H7 str. TW14359 8219000 YP_003080236.1 CDS ECSP_4435 NC_013008.1 4394734 4394991 D acyl carrier protein 4394734..4394991 Escherichia coli O157:H7 str. TW14359 8219001 YP_003080237.1 CDS ECSP_4436 NC_013008.1 4395003 4395254 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 4395003..4395254 Escherichia coli O157:H7 str. TW14359 8219002 YP_003080238.1 CDS ECSP_4437 NC_013008.1 4395259 4395840 D hypothetical protein 4395259..4395840 Escherichia coli O157:H7 str. TW14359 8219003 YP_003080239.1 CDS ECSP_4439 NC_013008.1 4397185 4397538 D hypothetical protein 4397185..4397538 Escherichia coli O157:H7 str. TW14359 8219005 YP_003080240.1 CDS ECSP_4440 NC_013008.1 4397529 4399205 D hypothetical protein 4397529..4399205 Escherichia coli O157:H7 str. TW14359 8219006 YP_003080241.1 CDS ECSP_4441 NC_013008.1 4399209 4399631 D hypothetical protein 4399209..4399631 Escherichia coli O157:H7 str. TW14359 8219007 YP_003080242.1 CDS ECSP_4442 NC_013008.1 4399628 4400233 D hypothetical protein 4399628..4400233 Escherichia coli O157:H7 str. TW14359 8219008 YP_003080243.1 CDS ECSP_4443 NC_013008.1 4400271 4402520 D hypothetical protein 4400271..4402520 Escherichia coli O157:H7 str. TW14359 8219009 YP_003080244.1 CDS ECSP_4444 NC_013008.1 4402517 4403101 D hypothetical protein 4402517..4403101 Escherichia coli O157:H7 str. TW14359 8219010 YP_003080245.1 CDS ECSP_4445 NC_013008.1 4403103 4404272 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 4403103..4404272 Escherichia coli O157:H7 str. TW14359 8219011 YP_003080246.1 CDS ECSP_4446 NC_013008.1 4404269 4404733 D hypothetical protein 4404269..4404733 Escherichia coli O157:H7 str. TW14359 8219012 YP_003080247.1 CDS fabG NC_013008.1 4404733 4405464 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4404733..4405464 Escherichia coli O157:H7 str. TW14359 8219013 YP_003080248.1 CDS ECSP_4448 NC_013008.1 4405461 4406690 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 4405461..4406690 Escherichia coli O157:H7 str. TW14359 8219014 YP_003080249.1 CDS acpT NC_013008.1 4406692 4407279 D holo-(acyl carrier protein) synthase 2 4406692..4407279 Escherichia coli O157:H7 str. TW14359 8219015 YP_003080250.1 CDS nikA NC_013008.1 4407390 4408964 D nickel ABC transporter periplasmic-binding protein 4407390..4408964 Escherichia coli O157:H7 str. TW14359 8219016 YP_003080251.1 CDS nikB NC_013008.1 4408964 4409908 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4408964..4409908 Escherichia coli O157:H7 str. TW14359 8219017 YP_003080252.1 CDS nikC NC_013008.1 4409905 4410738 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4409905..4410738 Escherichia coli O157:H7 str. TW14359 8219018 YP_003080253.1 CDS nikD NC_013008.1 4410738 4411502 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4410738..4411502 Escherichia coli O157:H7 str. TW14359 8219019 YP_003080254.1 CDS nikE NC_013008.1 4411499 4412305 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4411499..4412305 Escherichia coli O157:H7 str. TW14359 8219020 YP_003080255.1 CDS nikR NC_013008.1 4412311 4412712 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4412311..4412712 Escherichia coli O157:H7 str. TW14359 8219021 YP_003080256.1 CDS ECSP_4456 NC_013008.1 4412902 4413657 D regulator 4412902..4413657 Escherichia coli O157:H7 str. TW14359 8219022 YP_003080257.1 CDS ECSP_4457 NC_013008.1 4413682 4414155 D phosphotransferase system enzyme subunit 4413682..4414155 Escherichia coli O157:H7 str. TW14359 8219023 YP_003080258.1 CDS ECSP_4458 NC_013008.1 4414152 4414433 D phosphotransferase system enzyme subunit 4414152..4414433 Escherichia coli O157:H7 str. TW14359 8219024 YP_003080259.1 CDS ECSP_4459 NC_013008.1 4414510 4415868 D phosphotransferase system enzyme subunit 4414510..4415868 Escherichia coli O157:H7 str. TW14359 8219025 YP_003080260.1 CDS ECSP_4460 NC_013008.1 4415861 4417369 D xylulose kinase 4415861..4417369 Escherichia coli O157:H7 str. TW14359 8219026 YP_003080261.1 CDS ECSP_4461 NC_013008.1 4417359 4417628 D phosphocarrier protein 4417359..4417628 Escherichia coli O157:H7 str. TW14359 8219027 YP_003080262.1 CDS gatY NC_013008.1 4417660 4418520 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 4417660..4418520 Escherichia coli O157:H7 str. TW14359 8219028 YP_003080263.1 CDS ECSP_4463 NC_013008.1 4418570 4418929 R hypothetical protein complement(4418570..4418929) Escherichia coli O157:H7 str. TW14359 8219029 YP_003080264.1 CDS ECSP_4464 NC_013008.1 4418926 4419201 R hypothetical protein complement(4418926..4419201) Escherichia coli O157:H7 str. TW14359 8219030 YP_003080265.1 CDS yhhJ NC_013008.1 4419274 4420398 R ABC transporter membrane protein complement(4419274..4420398) Escherichia coli O157:H7 str. TW14359 8219031 YP_003080266.1 CDS rbbA NC_013008.1 4420398 4423133 R fused ribosome-associated ATPase: ATP-binding protein, ATP-binding protein, membrane protein complement(4420398..4423133) Escherichia coli O157:H7 str. TW14359 8219032 YP_003080267.1 CDS yhiI NC_013008.1 4423130 4424197 R HlyD family secretion protein complement(4423130..4424197) Escherichia coli O157:H7 str. TW14359 8219033 YP_003080268.1 CDS yhiJ NC_013008.1 4424563 4426185 R hypothetical protein complement(4424563..4426185) Escherichia coli O157:H7 str. TW14359 8219034 YP_003080269.1 CDS ECSP_4469 NC_013008.1 4426447 4428057 R hypothetical protein complement(4426447..4428057) Escherichia coli O157:H7 str. TW14359 8219035 YP_003080270.1 CDS yhiM NC_013008.1 4428441 4429493 D hypothetical protein 4428441..4429493 Escherichia coli O157:H7 str. TW14359 8219036 YP_003080271.1 CDS ECSP_4471 NC_013008.1 4429520 4429675 R hypothetical protein complement(4429520..4429675) Escherichia coli O157:H7 str. TW14359 8219037 YP_003080272.1 CDS yhiN NC_013008.1 4429811 4431013 R oxidoreductase complement(4429811..4431013) Escherichia coli O157:H7 str. TW14359 8219038 YP_003080273.1 CDS pitA NC_013008.1 4431245 4432744 D phosphate transporter, low-affinity 4431245..4432744 Escherichia coli O157:H7 str. TW14359 8219039 YP_003080274.1 CDS uspB NC_013008.1 4432815 4433150 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(4432815..4433150) Escherichia coli O157:H7 str. TW14359 8219040 YP_003080275.1 CDS uspA NC_013008.1 4433541 4433975 D universal stress global response regulator 4433541..4433975 Escherichia coli O157:H7 str. TW14359 8219041 YP_003080276.1 CDS yhiP NC_013008.1 4434292 4435761 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4434292..4435761 Escherichia coli O157:H7 str. TW14359 8219042 YP_003080277.1 CDS yhiQ NC_013008.1 4435810 4436562 R predicted SAM-dependent methyltransferase; methyltransferase complement(4435810..4436562) Escherichia coli O157:H7 str. TW14359 8219043 YP_003080278.1 CDS prlC NC_013008.1 4436570 4438612 R oligopeptidase A complement(4436570..4438612) Escherichia coli O157:H7 str. TW14359 8219044 YP_003080279.1 CDS yhiR NC_013008.1 4438815 4439657 D DNA (exogenous) processing protein 4438815..4439657 Escherichia coli O157:H7 str. TW14359 8219045 YP_003080280.1 CDS gor NC_013008.1 4439729 4441081 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4439729..4441081 Escherichia coli O157:H7 str. TW14359 8219046 YP_003080281.1 CDS arsR NC_013008.1 4441962 4442315 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 4441962..4442315 Escherichia coli O157:H7 str. TW14359 8219047 YP_003080282.1 CDS arsB NC_013008.1 4442369 4443658 D arsenite/antimonite transporter 4442369..4443658 Escherichia coli O157:H7 str. TW14359 8219048 YP_003080283.1 CDS arsC NC_013008.1 4443671 4444096 D arsenate reductase 4443671..4444096 Escherichia coli O157:H7 str. TW14359 8219049 YP_003080284.1 CDS ECSP_4484 NC_013008.1 4444208 4444315 D hypothetical protein 4444208..4444315 Escherichia coli O157:H7 str. TW14359 8219050 YP_003080285.1 CDS yhiS NC_013008.1 4444723 4445838 D hypothetical protein 4444723..4445838 Escherichia coli O157:H7 str. TW14359 8219051 YP_003080286.1 CDS slp NC_013008.1 4446192 4446758 D outer membrane lipoprotein 4446192..4446758 Escherichia coli O157:H7 str. TW14359 8219052 YP_003080287.1 CDS yhiF NC_013008.1 4446914 4447444 D DNA-binding transcriptional regulator 4446914..4447444 Escherichia coli O157:H7 str. TW14359 8219053 YP_003080288.1 CDS chuS NC_013008.1 4447505 4448533 R heme oxygenase complement(4447505..4448533) Escherichia coli O157:H7 str. TW14359 8219054 YP_003080289.1 CDS chuA NC_013008.1 4448582 4450564 R outer membrane heme/hemoglobin receptor complement(4448582..4450564) Escherichia coli O157:H7 str. TW14359 8219055 YP_003080290.1 CDS ECSP_4490 NC_013008.1 4450840 4451139 R hypothetical protein complement(4450840..4451139) Escherichia coli O157:H7 str. TW14359 8219056 YP_003080291.1 CDS chuT NC_013008.1 4451247 4452161 D periplasmic heme-binding protein 4451247..4452161 Escherichia coli O157:H7 str. TW14359 8219057 YP_003080292.1 CDS chuW NC_013008.1 4452181 4453518 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4452181..4453518 Escherichia coli O157:H7 str. TW14359 8219058 YP_003080293.1 CDS chuX NC_013008.1 4453531 4454025 D hypothetical protein 4453531..4454025 Escherichia coli O157:H7 str. TW14359 8219059 YP_003080294.1 CDS chuY NC_013008.1 4454025 4454648 D hypothetical protein 4454025..4454648 Escherichia coli O157:H7 str. TW14359 8219060 YP_003080295.1 CDS chuU NC_013008.1 4454697 4455689 D permease of iron compound ABC transport system 4454697..4455689 Escherichia coli O157:H7 str. TW14359 8219061 YP_003080296.1 CDS hmuV NC_013008.1 4455686 4456456 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4455686..4456456 Escherichia coli O157:H7 str. TW14359 8219062 YP_003080297.1 CDS yhiD NC_013008.1 4456508 4457155 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(4456508..4457155) Escherichia coli O157:H7 str. TW14359 8219063 YP_003080298.1 CDS hdeB NC_013008.1 4457219 4457557 R acid-resistance protein complement(4457219..4457557) Escherichia coli O157:H7 str. TW14359 8219064 YP_003080299.1 CDS hdeA NC_013008.1 4457661 4457993 R inactive form; acid-resistance protein complement(4457661..4457993) Escherichia coli O157:H7 str. TW14359 8219065 YP_003080300.1 CDS hdeD NC_013008.1 4458248 4458820 D acid-resistance membrane protein 4458248..4458820 Escherichia coli O157:H7 str. TW14359 8219066 YP_003080301.1 CDS gadE NC_013008.1 4459619 4460146 D acid-induced positive regulator of glutamate-dependent acid resistance 4459619..4460146 Escherichia coli O157:H7 str. TW14359 8219067 YP_003080302.1 CDS mdtE NC_013008.1 4460485 4461642 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4460485..4461642 Escherichia coli O157:H7 str. TW14359 8219068 YP_003080303.1 CDS mdtF NC_013008.1 4461667 4464780 D multidrug transporter, RpoS-dependent 4461667..4464780 Escherichia coli O157:H7 str. TW14359 8219069 YP_003080304.1 CDS gadW NC_013008.1 4465143 4465871 R DNA-binding transcriptional activator complement(4465143..4465871) Escherichia coli O157:H7 str. TW14359 8219070 YP_003080305.1 CDS ECSP_4505 NC_013008.1 4465944 4466051 R hypothetical protein complement(4465944..4466051) Escherichia coli O157:H7 str. TW14359 8219071 YP_003080306.1 CDS gadX NC_013008.1 4466239 4467063 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(4466239..4467063) Escherichia coli O157:H7 str. TW14359 8219072 YP_003080307.1 CDS gadA NC_013008.1 4467434 4468834 R glutamate decarboxylase A, PLP-dependent complement(4467434..4468834) Escherichia coli O157:H7 str. TW14359 8219073 YP_003080308.1 CDS yhjA NC_013008.1 4469045 4470442 R cytochrome C peroxidase complement(4469045..4470442) Escherichia coli O157:H7 str. TW14359 8219074 YP_003080309.1 CDS treF NC_013008.1 4470847 4472496 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4470847..4472496 Escherichia coli O157:H7 str. TW14359 8219075 YP_003080310.1 CDS yhjB NC_013008.1 4472547 4473149 R DNA-binding response regulator in two-component regulatory system complement(4472547..4473149) Escherichia coli O157:H7 str. TW14359 8219076 YP_003080311.1 CDS yhjC NC_013008.1 4473669 4474568 D DNA-binding transcriptional regulator 4473669..4474568 Escherichia coli O157:H7 str. TW14359 8219077 YP_003080312.1 CDS yhjD NC_013008.1 4474617 4475630 D hypothetical protein 4474617..4475630 Escherichia coli O157:H7 str. TW14359 8219078 YP_003080313.1 CDS yhjE NC_013008.1 4476042 4477364 D transporter 4476042..4477364 Escherichia coli O157:H7 str. TW14359 8219079 YP_003080314.1 CDS yhjG NC_013008.1 4477546 4479606 R outer membrane biogenesis protein complement(4477546..4479606) Escherichia coli O157:H7 str. TW14359 8219080 YP_003080315.1 CDS yhjH NC_013008.1 4479676 4480443 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(4479676..4480443) Escherichia coli O157:H7 str. TW14359 8219081 YP_003080316.1 CDS kdgK NC_013008.1 4480675 4481604 D ketodeoxygluconokinase 4480675..4481604 Escherichia coli O157:H7 str. TW14359 8219082 YP_003080317.1 CDS yhjJ NC_013008.1 4481700 4483196 R zinc-dependent peptidase complement(4481700..4483196) Escherichia coli O157:H7 str. TW14359 8219083 YP_003080318.1 CDS dctA NC_013008.1 4483417 4484703 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(4483417..4484703) Escherichia coli O157:H7 str. TW14359 8219084 YP_003080319.1 CDS yhjK NC_013008.1 4484886 4486874 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase complement(4484886..4486874) Escherichia coli O157:H7 str. TW14359 8219085 YP_003080320.1 CDS bcsC NC_013008.1 4486956 4489964 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(4486956..4489964) Escherichia coli O157:H7 str. TW14359 8219086 YP_003080321.1 CDS bcsZ NC_013008.1 4490411 4491517 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(4490411..4491517) Escherichia coli O157:H7 str. TW14359 8219087 YP_003080322.1 CDS bcsB NC_013008.1 4491524 4493899 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(4491524..4493899) Escherichia coli O157:H7 str. TW14359 8219088 YP_003080323.1 CDS bcsA NC_013008.1 4493910 4496528 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(4493910..4496528) Escherichia coli O157:H7 str. TW14359 8219089 YP_003080324.1 CDS ECSP_4524 NC_013008.1 4497080 4497277 R hypothetical protein complement(4497080..4497277) Escherichia coli O157:H7 str. TW14359 8219090 YP_003080325.1 CDS yhjR NC_013008.1 4497289 4497477 R hypothetical protein complement(4497289..4497477) Escherichia coli O157:H7 str. TW14359 8219091 YP_003080326.1 CDS bcsE NC_013008.1 4497750 4499321 D hypothetical protein 4497750..4499321 Escherichia coli O157:H7 str. TW14359 8219092 YP_003080327.1 CDS bcsF NC_013008.1 4499318 4499509 D hypothetical protein 4499318..4499509 Escherichia coli O157:H7 str. TW14359 8219093 YP_003080328.1 CDS bcsG NC_013008.1 4499506 4501185 D inner membrane protein 4499506..4501185 Escherichia coli O157:H7 str. TW14359 8219094 YP_003080329.1 CDS ldrD NC_013008.1 4501272 4501379 R toxic polypeptide, small complement(4501272..4501379) Escherichia coli O157:H7 str. TW14359 8219095 YP_003080330.1 CDS yhjV NC_013008.1 4501855 4503126 D transporter 4501855..4503126 Escherichia coli O157:H7 str. TW14359 8219096 YP_003080331.1 CDS dppF NC_013008.1 4503156 4504160 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(4503156..4504160) Escherichia coli O157:H7 str. TW14359 8219097 YP_003080332.1 CDS dppD NC_013008.1 4504157 4505140 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(4504157..4505140) Escherichia coli O157:H7 str. TW14359 8219098 YP_003080333.1 CDS dppC NC_013008.1 4505151 4506053 R dipeptide transporter complement(4505151..4506053) Escherichia coli O157:H7 str. TW14359 8219099 YP_003080334.1 CDS dppB NC_013008.1 4506063 4507082 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(4506063..4507082) Escherichia coli O157:H7 str. TW14359 8219100 YP_003080335.1 CDS dppA NC_013008.1 4507233 4508840 R dipeptide ABC transporter periplasmic-binding protein complement(4507233..4508840) Escherichia coli O157:H7 str. TW14359 8219101 YP_003080336.1 CDS eptB NC_013008.1 4509753 4511444 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(4509753..4511444) Escherichia coli O157:H7 str. TW14359 8219103 YP_003080337.1 CDS lpfE NC_013008.1 4511699 4512229 R fimbrial subunit complement(4511699..4512229) Escherichia coli O157:H7 str. TW14359 8219104 YP_003080338.1 CDS lpfD NC_013008.1 4512234 4513289 R fimbrial protein complement(4512234..4513289) Escherichia coli O157:H7 str. TW14359 8219105 YP_003080339.1 CDS lpfB NC_013008.1 4515906 4516592 R fimbrial chaperone complement(4515906..4516592) Escherichia coli O157:H7 str. TW14359 8219107 YP_003080340.1 CDS lpfA NC_013008.1 4516657 4517193 R major fimbrial subunit complement(4516657..4517193) Escherichia coli O157:H7 str. TW14359 8219108 YP_003080341.1 CDS yhjX NC_013008.1 4517525 4518727 R transporter complement(4517525..4518727) Escherichia coli O157:H7 str. TW14359 8219109 YP_003080342.1 CDS yhjY NC_013008.1 4518956 4519654 R hypothetical protein complement(4518956..4519654) Escherichia coli O157:H7 str. TW14359 8219110 YP_003080343.1 CDS tag NC_013008.1 4519812 4520375 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 4519812..4520375 Escherichia coli O157:H7 str. TW14359 8219111 YP_003080344.1 CDS yiaC NC_013008.1 4520372 4520812 D hypothetical protein 4520372..4520812 Escherichia coli O157:H7 str. TW14359 8219112 YP_003080345.1 CDS bisC NC_013008.1 4520781 4523114 R biotin sulfoxide reductase complement(4520781..4523114) Escherichia coli O157:H7 str. TW14359 8219113 YP_003080346.1 CDS yiaD NC_013008.1 4523267 4523926 D outer membrane lipoprotein 4523267..4523926 Escherichia coli O157:H7 str. TW14359 8219114 YP_003080347.1 CDS ghrB NC_013008.1 4524030 4525004 D 2-keto-D-gluconate reductase 4524030..4525004 Escherichia coli O157:H7 str. TW14359 8219115 YP_003080348.1 CDS yiaF NC_013008.1 4525054 4525764 R hypothetical protein complement(4525054..4525764) Escherichia coli O157:H7 str. TW14359 8219116 YP_003080349.1 CDS yiaG NC_013008.1 4526198 4526488 D transcriptional regulator 4526198..4526488 Escherichia coli O157:H7 str. TW14359 8219117 YP_003080350.1 CDS cspA NC_013008.1 4526769 4526981 D major cold shock protein 4526769..4526981 Escherichia coli O157:H7 str. TW14359 8219118 YP_003080351.1 CDS hokA NC_013008.1 4527169 4527321 R small toxic polypeptide complement(4527169..4527321) Escherichia coli O157:H7 str. TW14359 8219119 YP_003080352.1 CDS glyS NC_013008.1 4527644 4529713 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(4527644..4529713) Escherichia coli O157:H7 str. TW14359 8219120 YP_003080353.1 CDS glyQ NC_013008.1 4529723 4530634 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(4529723..4530634) Escherichia coli O157:H7 str. TW14359 8219121 YP_003080354.1 CDS ysaB NC_013008.1 4530729 4531028 R hypothetical protein complement(4530729..4531028) Escherichia coli O157:H7 str. TW14359 8219122 YP_003080355.1 CDS yiaH NC_013008.1 4531203 4532198 D hypothetical protein 4531203..4532198 Escherichia coli O157:H7 str. TW14359 8219123 YP_003080356.1 CDS yiaA NC_013008.1 4532240 4532677 R hypothetical protein complement(4532240..4532677) Escherichia coli O157:H7 str. TW14359 8219124 YP_003080357.1 CDS yiaB NC_013008.1 4532723 4533064 R hypothetical protein complement(4532723..4533064) Escherichia coli O157:H7 str. TW14359 8219125 YP_003080358.1 CDS xylB NC_013008.1 4533233 4534687 R xylulokinase complement(4533233..4534687) Escherichia coli O157:H7 str. TW14359 8219126 YP_003080359.1 CDS xylA NC_013008.1 4534759 4536081 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(4534759..4536081) Escherichia coli O157:H7 str. TW14359 8219127 YP_003080360.1 CDS xylF NC_013008.1 4536447 4537439 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4536447..4537439 Escherichia coli O157:H7 str. TW14359 8219128 YP_003080361.1 CDS xylG NC_013008.1 4537517 4539058 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4537517..4539058 Escherichia coli O157:H7 str. TW14359 8219129 YP_003080362.1 CDS xylH NC_013008.1 4539036 4540217 D D-xylose ABC transporter membrane protein 4539036..4540217 Escherichia coli O157:H7 str. TW14359 8219130 YP_003080363.1 CDS xylR NC_013008.1 4540295 4541473 D DNA-binding transcriptional activator, xylose-binding 4540295..4541473 Escherichia coli O157:H7 str. TW14359 8219131 YP_003080364.1 CDS bax NC_013008.1 4541581 4542405 R hypothetical protein complement(4541581..4542405) Escherichia coli O157:H7 str. TW14359 8219132 YP_003080365.1 CDS malS NC_013008.1 4542725 4544755 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4542725..4544755 Escherichia coli O157:H7 str. TW14359 8219133 YP_003080366.1 CDS avtA NC_013008.1 4544933 4546186 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4544933..4546186 Escherichia coli O157:H7 str. TW14359 8219134 YP_003080367.1 CDS ysaA NC_013008.1 4546338 4546811 R hydrogenase, 4Fe-4S ferredoxin-type component complement(4546338..4546811) Escherichia coli O157:H7 str. TW14359 8219135 YP_003080368.1 CDS ECSP_4570 NC_013008.1 4546362 4546706 D hypothetical protein 4546362..4546706 Escherichia coli O157:H7 str. TW14359 8219136 YP_003080369.1 CDS ECSP_4571 NC_013008.1 4547055 4547870 R regulatory protein complement(4547055..4547870) Escherichia coli O157:H7 str. TW14359 8219137 YP_003080370.1 CDS ECSP_4572 NC_013008.1 4548096 4549496 D permease 4548096..4549496 Escherichia coli O157:H7 str. TW14359 8219138 YP_003080371.1 CDS ECSP_4573 NC_013008.1 4549507 4551477 D hypothetical protein 4549507..4551477 Escherichia coli O157:H7 str. TW14359 8219139 YP_003080372.1 CDS yiaT NC_013008.1 4551607 4552347 R hypothetical protein complement(4551607..4552347) Escherichia coli O157:H7 str. TW14359 8219140 YP_003080373.1 CDS yiaU NC_013008.1 4552471 4553445 D DNA-binding transcriptional regulator 4552471..4553445 Escherichia coli O157:H7 str. TW14359 8219141 YP_003080374.1 CDS yiaV NC_013008.1 4553442 4554578 R membrane fusion protein (MFP) component of efflux pump, signal anchor complement(4553442..4554578) Escherichia coli O157:H7 str. TW14359 8219142 YP_003080375.1 CDS yiaW NC_013008.1 4554584 4554907 R hypothetical protein complement(4554584..4554907) Escherichia coli O157:H7 str. TW14359 8219143 YP_003080376.1 CDS ECSP_4578 NC_013008.1 4554950 4555069 D hypothetical protein 4554950..4555069 Escherichia coli O157:H7 str. TW14359 8219144 YP_003080377.1 CDS ECSP_4579 NC_013008.1 4555069 4555233 D hypothetical protein 4555069..4555233 Escherichia coli O157:H7 str. TW14359 8219145 YP_003080378.1 CDS aldB NC_013008.1 4555452 4556990 R aldehyde dehydrogenase complement(4555452..4556990) Escherichia coli O157:H7 str. TW14359 8219146 YP_003080379.1 CDS ECSP_4581 NC_013008.1 4557098 4558393 R hypothetical protein complement(4557098..4558393) Escherichia coli O157:H7 str. TW14359 8219147 YP_003080380.1 CDS yiaY NC_013008.1 4558523 4559674 R alcohol dehydrogenase complement(4558523..4559674) Escherichia coli O157:H7 str. TW14359 8219148 YP_003080381.1 CDS selB NC_013008.1 4559863 4561707 R selenocysteinyl-tRNA-specific translation factor complement(4559863..4561707) Escherichia coli O157:H7 str. TW14359 8219149 YP_003080382.1 CDS selA NC_013008.1 4561704 4563095 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4561704..4563095) Escherichia coli O157:H7 str. TW14359 8219150 YP_003080383.1 CDS yibF NC_013008.1 4563193 4563801 R glutathione S-transferase complement(4563193..4563801) Escherichia coli O157:H7 str. TW14359 8219151 YP_003080384.1 CDS yibJ NC_013008.1 4567315 4568259 D Rhs-family protein 4567315..4568259 Escherichia coli O157:H7 str. TW14359 8219152 YP_003080385.1 CDS yibG NC_013008.1 4568271 4568732 D hypothetical protein 4568271..4568732 Escherichia coli O157:H7 str. TW14359 8219153 YP_003080386.1 CDS ECSP_4588 NC_013008.1 4568953 4569072 D hypothetical protein 4568953..4569072 Escherichia coli O157:H7 str. TW14359 8219154 YP_003080387.1 CDS ECSP_4589 NC_013008.1 4569439 4569876 D hypothetical protein 4569439..4569876 Escherichia coli O157:H7 str. TW14359 8219155 YP_003080388.1 CDS yibH NC_013008.1 4570335 4571471 R hypothetical protein complement(4570335..4571471) Escherichia coli O157:H7 str. TW14359 8219156 YP_003080389.1 CDS yibI NC_013008.1 4571474 4571836 R inner membrane protein complement(4571474..4571836) Escherichia coli O157:H7 str. TW14359 8219157 YP_003080390.1 CDS mtlA NC_013008.1 4572373 4574286 D PTS system mannitol-specific transporter subunit IIABC 4572373..4574286 Escherichia coli O157:H7 str. TW14359 8219158 YP_003080391.1 CDS mtlD NC_013008.1 4574381 4575529 D mannitol-1-phosphate 5-dehydrogenase 4574381..4575529 Escherichia coli O157:H7 str. TW14359 8219159 YP_003080392.1 CDS mtlR NC_013008.1 4575529 4576116 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4575529..4576116 Escherichia coli O157:H7 str. TW14359 8219160 YP_003080393.1 CDS yibT NC_013008.1 4576128 4576337 R hypothetical protein complement(4576128..4576337) Escherichia coli O157:H7 str. TW14359 8219161 YP_003080394.1 CDS yibL NC_013008.1 4576622 4576984 D hypothetical protein 4576622..4576984 Escherichia coli O157:H7 str. TW14359 8219162 YP_003080395.1 CDS ECSP_4597 NC_013008.1 4577298 4577456 R hypothetical protein complement(4577298..4577456) Escherichia coli O157:H7 str. TW14359 8219163 YP_003080396.1 CDS ECSP_4598 NC_013008.1 4577629 4578210 D hypothetical protein 4577629..4578210 Escherichia coli O157:H7 str. TW14359 8219164 YP_003080397.1 CDS ECSP_4599 NC_013008.1 4578254 4583020 D adhesin 4578254..4583020 Escherichia coli O157:H7 str. TW14359 8219165 YP_003080398.1 CDS lldP NC_013008.1 4583388 4585043 D L-lactate permease 4583388..4585043 Escherichia coli O157:H7 str. TW14359 8219166 YP_003080399.1 CDS lldR NC_013008.1 4585043 4585819 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4585043..4585819 Escherichia coli O157:H7 str. TW14359 8219167 YP_003080400.1 CDS lldD NC_013008.1 4585816 4587006 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4585816..4587006 Escherichia coli O157:H7 str. TW14359 8219168 YP_003080401.1 CDS yibK NC_013008.1 4587192 4587665 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4587192..4587665 Escherichia coli O157:H7 str. TW14359 8219169 YP_003080402.1 CDS cysE NC_013008.1 4587718 4588539 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4587718..4588539) Escherichia coli O157:H7 str. TW14359 8219170 YP_003080403.1 CDS gpsA NC_013008.1 4588619 4589638 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4588619..4589638) Escherichia coli O157:H7 str. TW14359 8219171 YP_003080404.1 CDS secB NC_013008.1 4589638 4590105 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4589638..4590105) Escherichia coli O157:H7 str. TW14359 8219172 YP_003080405.1 CDS grxC NC_013008.1 4590168 4590419 R glutaredoxin 3 complement(4590168..4590419) Escherichia coli O157:H7 str. TW14359 8219173 YP_003080406.1 CDS yibN NC_013008.1 4590561 4590992 R rhodanese-related sulfurtransferase complement(4590561..4590992) Escherichia coli O157:H7 str. TW14359 8219174 YP_003080407.1 CDS gpmI NC_013008.1 4591237 4592781 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4591237..4592781 Escherichia coli O157:H7 str. TW14359 8219175 YP_003080408.1 CDS envC NC_013008.1 4592815 4594074 D hypothetical protein 4592815..4594074 Escherichia coli O157:H7 str. TW14359 8219176 YP_003080409.1 CDS yibQ NC_013008.1 4594078 4595037 D polysaccharide deacetylase 4594078..4595037 Escherichia coli O157:H7 str. TW14359 8219177 YP_003080410.1 CDS yibD NC_013008.1 4595043 4596059 R glycosyl transferase complement(4595043..4596059) Escherichia coli O157:H7 str. TW14359 8219178 YP_003080411.1 CDS tdh NC_013008.1 4596298 4597323 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4596298..4597323) Escherichia coli O157:H7 str. TW14359 8219179 YP_003080412.1 CDS kbl NC_013008.1 4597333 4598529 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase complement(4597333..4598529) Escherichia coli O157:H7 str. TW14359 8219180 YP_003080413.1 CDS htrL NC_013008.1 4598804 4599661 R hypothetical protein complement(4598804..4599661) Escherichia coli O157:H7 str. TW14359 8219181 YP_003080414.1 CDS rfaD NC_013008.1 4599965 4600897 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4599965..4600897 Escherichia coli O157:H7 str. TW14359 8219182 YP_003080415.1 CDS rfaF NC_013008.1 4600907 4601953 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4600907..4601953 Escherichia coli O157:H7 str. TW14359 8219183 YP_003080416.1 CDS rfaC NC_013008.1 4601957 4602949 D ADP-heptose:LPS heptosyl transferase I 4601957..4602949 Escherichia coli O157:H7 str. TW14359 8219184 YP_003080417.1 CDS waaL NC_013008.1 4602946 4604154 D LPS biosynthesis enzyme 4602946..4604154 Escherichia coli O157:H7 str. TW14359 8219185 YP_003080418.1 CDS waaD NC_013008.1 4604190 4605332 R UDP-glucose:(glucosyl) LPS alpha-1,2-glucosyltransferase complement(4604190..4605332) Escherichia coli O157:H7 str. TW14359 8219186 YP_003080419.1 CDS waaJ NC_013008.1 4605341 4606354 R UDP-glucose:(galactosyl) LPS alpha-1,2-glucosyltransferase complement(4605341..4606354) Escherichia coli O157:H7 str. TW14359 8219187 YP_003080420.1 CDS waaY NC_013008.1 4606379 4607086 R lipopolysaccharide core biosynthesis protein complement(4606379..4607086) Escherichia coli O157:H7 str. TW14359 8219188 YP_003080421.1 CDS waaI NC_013008.1 4607112 4608119 R LPS biosynthesis enzyme complement(4607112..4608119) Escherichia coli O157:H7 str. TW14359 8219189 YP_003080422.1 CDS waaP NC_013008.1 4608162 4608959 R kinase that phosphorylates core heptose of lipopolysaccharide complement(4608162..4608959) Escherichia coli O157:H7 str. TW14359 8219190 YP_003080423.1 CDS rfaG NC_013008.1 4608952 4610076 R glucosyltransferase I complement(4608952..4610076) Escherichia coli O157:H7 str. TW14359 8219191 YP_003080424.1 CDS ECSP_4626 NC_013008.1 4610073 4611095 R lipopolysaccharide core biosynthesis protein complement(4610073..4611095) Escherichia coli O157:H7 str. TW14359 8219192 YP_003080425.1 CDS kdtA NC_013008.1 4611544 4612821 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4611544..4612821 Escherichia coli O157:H7 str. TW14359 8219193 YP_003080426.1 CDS coaD NC_013008.1 4612829 4613308 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4612829..4613308 Escherichia coli O157:H7 str. TW14359 8219194 YP_003080427.1 CDS mutM NC_013008.1 4613347 4614156 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4613347..4614156) Escherichia coli O157:H7 str. TW14359 8219195 YP_003080428.1 CDS rpmG NC_013008.1 4614254 4614421 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4614254..4614421) Escherichia coli O157:H7 str. TW14359 8219196 YP_003080429.1 CDS rpmB NC_013008.1 4614442 4614678 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4614442..4614678) Escherichia coli O157:H7 str. TW14359 8219197 YP_003080430.1 CDS radC NC_013008.1 4614895 4615563 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4614895..4615563) Escherichia coli O157:H7 str. TW14359 8219198 YP_003080431.1 CDS dfp NC_013008.1 4615735 4616955 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4615735..4616955 Escherichia coli O157:H7 str. TW14359 8219199 YP_003080432.1 CDS dut NC_013008.1 4616936 4617391 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4616936..4617391 Escherichia coli O157:H7 str. TW14359 8219200 YP_003080433.1 CDS slmA NC_013008.1 4617498 4618094 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4617498..4618094 Escherichia coli O157:H7 str. TW14359 8219201 YP_003080434.1 CDS pyrE NC_013008.1 4618131 4618772 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4618131..4618772) Escherichia coli O157:H7 str. TW14359 8219202 YP_003080435.1 CDS rph NC_013008.1 4618838 4619554 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4618838..4619554) Escherichia coli O157:H7 str. TW14359 8219203 YP_003080436.1 CDS yicC NC_013008.1 4619681 4620544 D hypothetical protein 4619681..4620544 Escherichia coli O157:H7 str. TW14359 8219204 YP_003080437.1 CDS dinD NC_013008.1 4620765 4621589 D DNA-damage-inducible protein D 4620765..4621589 Escherichia coli O157:H7 str. TW14359 8219205 YP_003080438.1 CDS yicG NC_013008.1 4621881 4622498 D hypothetical protein 4621881..4622498 Escherichia coli O157:H7 str. TW14359 8219206 YP_003080439.1 CDS ligB NC_013008.1 4622495 4624177 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4622495..4624177) Escherichia coli O157:H7 str. TW14359 8219207 YP_003080440.1 CDS gmk NC_013008.1 4624435 4625058 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4624435..4625058 Escherichia coli O157:H7 str. TW14359 8219208 YP_003080441.1 CDS rpoZ NC_013008.1 4625113 4625388 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4625113..4625388 Escherichia coli O157:H7 str. TW14359 8219209 YP_003080442.1 CDS spoT NC_013008.1 4625407 4627515 D bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4625407..4627515 Escherichia coli O157:H7 str. TW14359 8219210 YP_003080443.1 CDS trmH NC_013008.1 4627522 4628211 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4627522..4628211 Escherichia coli O157:H7 str. TW14359 8219211 YP_003080444.1 CDS recG NC_013008.1 4628217 4630298 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4628217..4630298 Escherichia coli O157:H7 str. TW14359 8219212 YP_003080445.1 CDS ECSP_4647 NC_013008.1 4630283 4631149 R hypothetical protein complement(4630283..4631149) Escherichia coli O157:H7 str. TW14359 8219213 YP_003080446.1 CDS gltS NC_013008.1 4631152 4632357 R glutamate transporter complement(4631152..4632357) Escherichia coli O157:H7 str. TW14359 8219214 YP_003080447.1 CDS yicE NC_013008.1 4632637 4634028 D transporter 4632637..4634028 Escherichia coli O157:H7 str. TW14359 8219215 YP_003080448.1 CDS yicH NC_013008.1 4634149 4635858 D hypothetical protein 4634149..4635858 Escherichia coli O157:H7 str. TW14359 8219216 YP_003080449.1 CDS yicI NC_013008.1 4635911 4638229 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI complement(4635911..4638229) Escherichia coli O157:H7 str. TW14359 8219217 YP_003080450.1 CDS yicJ NC_013008.1 4638239 4639621 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4638239..4639621) Escherichia coli O157:H7 str. TW14359 8219218 YP_003080451.1 CDS intL NC_013008.1 4640204 4641385 D integrase for prophage 933L and the LEE pathogenicity island 4640204..4641385 Escherichia coli O157:H7 str. TW14359 8219219 YP_003080452.1 CDS ECSP_4654 NC_013008.1 4641484 4641834 D hypothetical protein 4641484..4641834 Escherichia coli O157:H7 str. TW14359 8219220 YP_003080453.1 CDS ECSP_4655 NC_013008.1 4642023 4642700 D transposase 4642023..4642700 Escherichia coli O157:H7 str. TW14359 8219221 YP_003080454.1 CDS ECSP_4656 NC_013008.1 4642951 4643325 D hypothetical protein 4642951..4643325 Escherichia coli O157:H7 str. TW14359 8219222 YP_003080455.1 CDS ECSP_4657 NC_013008.1 4643322 4643813 D hypothetical protein 4643322..4643813 Escherichia coli O157:H7 str. TW14359 8219223 YP_003080456.1 CDS ECSP_4658 NC_013008.1 4643825 4644022 D hypothetical protein 4643825..4644022 Escherichia coli O157:H7 str. TW14359 8219224 YP_003080457.1 CDS ECSP_4660 NC_013008.1 4644964 4645065 D hypothetical protein 4644964..4645065 Escherichia coli O157:H7 str. TW14359 8219226 YP_003080458.1 CDS ECSP_4661 NC_013008.1 4645225 4645605 D transposase, ISEc8 4645225..4645605 Escherichia coli O157:H7 str. TW14359 8219227 YP_003080459.1 CDS ECSP_4662 NC_013008.1 4645602 4645949 D transposase 4645602..4645949 Escherichia coli O157:H7 str. TW14359 8219228 YP_003080460.1 CDS ECSP_4663 NC_013008.1 4645999 4647537 D transposase, ISEc8 4645999..4647537 Escherichia coli O157:H7 str. TW14359 8219229 YP_003080461.1 CDS ECSP_4664 NC_013008.1 4647977 4648096 R hypothetical protein complement(4647977..4648096) Escherichia coli O157:H7 str. TW14359 8219230 YP_003080462.1 CDS espF NC_013008.1 4648402 4649148 R LEE-encoded type III effector complement(4648402..4649148) Escherichia coli O157:H7 str. TW14359 8219231 YP_003080463.1 CDS orf29 NC_013008.1 4649233 4649511 R LEE-encoded type III secretion system factor complement(4649233..4649511) Escherichia coli O157:H7 str. TW14359 8219232 YP_003080464.1 CDS escF NC_013008.1 4649517 4649738 R LEE-encoded type III secretion system component complement(4649517..4649738) Escherichia coli O157:H7 str. TW14359 8219233 YP_003080465.1 CDS ECSP_4668 NC_013008.1 4649774 4650181 R chaperone complement(4649774..4650181) Escherichia coli O157:H7 str. TW14359 8219234 YP_003080466.1 CDS espB NC_013008.1 4650188 4651126 R hypothetical protein EspB complement(4650188..4651126) Escherichia coli O157:H7 str. TW14359 8219235 YP_003080467.1 CDS espD NC_013008.1 4651147 4652271 R hypothetical protein EspD complement(4651147..4652271) Escherichia coli O157:H7 str. TW14359 8219236 YP_003080468.1 CDS espA NC_013008.1 4652284 4652862 R hypothetical protein EspA complement(4652284..4652862) Escherichia coli O157:H7 str. TW14359 8219237 YP_003080469.1 CDS sepL NC_013008.1 4652921 4653976 R LEE-encoded type III secretion system component complement(4652921..4653976) Escherichia coli O157:H7 str. TW14359 8219238 YP_003080470.1 CDS escD NC_013008.1 4654119 4655339 D LEE-encoded type III secretion system component 4654119..4655339 Escherichia coli O157:H7 str. TW14359 8219239 YP_003080471.1 CDS eae NC_013008.1 4655603 4658407 R intimin adherence protein complement(4655603..4658407) Escherichia coli O157:H7 str. TW14359 8219240 YP_003080472.1 CDS cesT NC_013008.1 4658467 4658937 R molecular chaperone complement(4658467..4658937) Escherichia coli O157:H7 str. TW14359 8219241 YP_003080473.1 CDS tir NC_013008.1 4659075 4660751 R translocated intimin receptor protein complement(4659075..4660751) Escherichia coli O157:H7 str. TW14359 8219242 YP_003080474.1 CDS ECSP_4677 NC_013008.1 4661175 4661786 R similar to mitochondrial associated type III effector protein; type III effector protein complement(4661175..4661786) Escherichia coli O157:H7 str. TW14359 8219243 YP_003080475.1 CDS cesF NC_013008.1 4662052 4662435 D chaperone for type III secretion of EspF 4662052..4662435 Escherichia coli O157:H7 str. TW14359 8219244 YP_003080476.1 CDS espH NC_013008.1 4662633 4663139 R LEE-encoded type III effector complement(4662633..4663139) Escherichia coli O157:H7 str. TW14359 8219245 YP_003080477.1 CDS escQ NC_013008.1 4663170 4664087 R LEE-encoded type III secretion system factor complement(4663170..4664087) Escherichia coli O157:H7 str. TW14359 8219246 YP_003080478.1 CDS orf16 NC_013008.1 4664050 4664466 R LEE-encoded type III secretion system factor complement(4664050..4664466) Escherichia coli O157:H7 str. TW14359 8219247 YP_003080479.1 CDS orf15 NC_013008.1 4664459 4664836 R LEE-encoded type III secretion system factor complement(4664459..4664836) Escherichia coli O157:H7 str. TW14359 8219248 YP_003080480.1 CDS escN NC_013008.1 4664839 4666179 R LEE-encoded type III secretion system factor complement(4664839..4666179) Escherichia coli O157:H7 str. TW14359 8219249 YP_003080481.1 CDS escV NC_013008.1 4666163 4668190 R LEE-encoded type III secretion system factor complement(4666163..4668190) Escherichia coli O157:H7 str. TW14359 8219250 YP_003080482.1 CDS orf12 NC_013008.1 4668187 4668540 R LEE-encoded type III secretion system factor complement(4668187..4668540) Escherichia coli O157:H7 str. TW14359 8219251 YP_003080483.1 CDS espZ NC_013008.1 4668725 4669024 D translocated effector protein 4668725..4669024 Escherichia coli O157:H7 str. TW14359 8219252 YP_003080484.1 CDS escI NC_013008.1 4669057 4669485 D LEE-encoded type III secretion system component 4669057..4669485 Escherichia coli O157:H7 str. TW14359 8219253 YP_003080485.1 CDS escJ NC_013008.1 4669488 4670060 D LEE-encoded type III secretion system factor 4669488..4670060 Escherichia coli O157:H7 str. TW14359 8219254 YP_003080486.1 CDS sepD NC_013008.1 4670066 4670521 D LEE-encoded type III secretion system component 4670066..4670521 Escherichia coli O157:H7 str. TW14359 8219255 YP_003080487.1 CDS escC NC_013008.1 4670521 4672059 D type III needle complex subunit 4670521..4672059 Escherichia coli O157:H7 str. TW14359 8219256 YP_003080488.1 CDS cesD NC_013008.1 4672073 4672528 D LEE-encoded type III secretion system factor 4672073..4672528 Escherichia coli O157:H7 str. TW14359 8219257 YP_003080489.1 CDS grlA NC_013008.1 4672912 4673325 R LEE-encoded positive regulator of transcription complement(4672912..4673325) Escherichia coli O157:H7 str. TW14359 8219258 YP_003080490.1 CDS grlR NC_013008.1 4673380 4673751 R negative regulator GrlR complement(4673380..4673751) Escherichia coli O157:H7 str. TW14359 8219259 YP_003080491.1 CDS etgA NC_013008.1 4673947 4674405 D lytic transglycosylase 4673947..4674405 Escherichia coli O157:H7 str. TW14359 8219260 YP_003080492.1 CDS escU NC_013008.1 4674402 4675439 R member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli; secretion system apparatus protein SsaU complement(4674402..4675439) Escherichia coli O157:H7 str. TW14359 8219261 YP_003080493.1 CDS escT NC_013008.1 4675432 4676208 R LEE-encoded type III secretion system factor complement(4675432..4676208) Escherichia coli O157:H7 str. TW14359 8219262 YP_003080494.1 CDS escS NC_013008.1 4676208 4676477 R LEE-encoded type III secretion system factor complement(4676208..4676477) Escherichia coli O157:H7 str. TW14359 8219263 YP_003080495.1 CDS escR NC_013008.1 4676477 4677130 R part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein complement(4676477..4677130) Escherichia coli O157:H7 str. TW14359 8219264 YP_003080496.1 CDS escL NC_013008.1 4677135 4677749 R LEE-encoded type III secretion system factor complement(4677135..4677749) Escherichia coli O157:H7 str. TW14359 8219265 YP_003080497.1 CDS orf4 NC_013008.1 4677775 4678374 R LEE-encoded type III secretion system factor complement(4677775..4678374) Escherichia coli O157:H7 str. TW14359 8219266 YP_003080498.1 CDS cesA NC_013008.1 4678371 4678694 R LEE-encoded chaperone complement(4678371..4678694) Escherichia coli O157:H7 str. TW14359 8219267 YP_003080499.1 CDS escE NC_013008.1 4678698 4678916 R LEE-encoded type III secretion system factor complement(4678698..4678916) Escherichia coli O157:H7 str. TW14359 8219268 YP_003080500.1 CDS ler NC_013008.1 4678931 4679302 R enterocyte effacement (LEE)-encoded regulator complement(4678931..4679302) Escherichia coli O157:H7 str. TW14359 8219269 YP_003080501.1 CDS espG NC_013008.1 4680565 4681761 D LEE-encoded type III effector 4680565..4681761 Escherichia coli O157:H7 str. TW14359 8219270 YP_003080502.1 CDS rorf1 NC_013008.1 4681889 4682707 D LEE-encoded type III secretion system factor 4681889..4682707 Escherichia coli O157:H7 str. TW14359 8219271 YP_003080503.1 CDS yicL NC_013008.1 4683727 4684650 D inner membrane protein 4683727..4684650 Escherichia coli O157:H7 str. TW14359 8219272 YP_003080504.1 CDS nlpA NC_013008.1 4684654 4685472 R cytoplasmic membrane lipoprotein-28 complement(4684654..4685472) Escherichia coli O157:H7 str. TW14359 8219273 YP_003080505.1 CDS yicS NC_013008.1 4685694 4685987 D hypothetical protein 4685694..4685987 Escherichia coli O157:H7 str. TW14359 8219274 YP_003080506.1 CDS nepI NC_013008.1 4686028 4687218 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4686028..4687218) Escherichia coli O157:H7 str. TW14359 8219275 YP_003080507.1 CDS ECSP_4710 NC_013008.1 4687452 4687805 D hypothetical protein 4687452..4687805 Escherichia coli O157:H7 str. TW14359 8219276 YP_003080508.1 CDS ECSP_4711 NC_013008.1 4687789 4688112 D hypothetical protein 4687789..4688112 Escherichia coli O157:H7 str. TW14359 8219277 YP_003080509.1 CDS yicN NC_013008.1 4688228 4688680 R hypothetical protein complement(4688228..4688680) Escherichia coli O157:H7 str. TW14359 8219278 YP_003080510.1 CDS ade NC_013008.1 4690241 4692007 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4690241..4692007 Escherichia coli O157:H7 str. TW14359 8219280 YP_003080511.1 CDS uhpT NC_013008.1 4692053 4693444 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4692053..4693444) Escherichia coli O157:H7 str. TW14359 8219281 YP_003080512.1 CDS uhpC NC_013008.1 4693582 4694901 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4693582..4694901) Escherichia coli O157:H7 str. TW14359 8219282 YP_003080513.1 CDS uhpB NC_013008.1 4694911 4696413 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4694911..4696413) Escherichia coli O157:H7 str. TW14359 8219283 YP_003080514.1 CDS uhpA NC_013008.1 4696413 4697003 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4696413..4697003) Escherichia coli O157:H7 str. TW14359 8219284 YP_003080515.1 CDS ilvN NC_013008.1 4700424 4700714 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4700424..4700714) Escherichia coli O157:H7 str. TW14359 8219287 YP_003080516.1 CDS ilvB NC_013008.1 4700718 4702406 R acetolactate synthase catalytic subunit complement(4700718..4702406) Escherichia coli O157:H7 str. TW14359 8219288 YP_003080517.1 CDS ECSP_4723 NC_013008.1 4702390 4702887 D hypothetical protein 4702390..4702887 Escherichia coli O157:H7 str. TW14359 8219289 YP_003080518.1 CDS ECSP_4724 NC_013008.1 4703344 4703517 D hypothetical protein 4703344..4703517 Escherichia coli O157:H7 str. TW14359 8219290 YP_003080519.1 CDS emrD NC_013008.1 4703544 4704728 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4703544..4704728 Escherichia coli O157:H7 str. TW14359 8219291 YP_003080520.1 CDS yidF NC_013008.1 4704736 4705233 R DNA-binding transcriptional regulator complement(4704736..4705233) Escherichia coli O157:H7 str. TW14359 8219292 YP_003080521.1 CDS yidG NC_013008.1 4705230 4705592 R inner membrane protein complement(4705230..4705592) Escherichia coli O157:H7 str. TW14359 8219293 YP_003080522.1 CDS yidH NC_013008.1 4705582 4705929 R hypothetical protein complement(4705582..4705929) Escherichia coli O157:H7 str. TW14359 8219294 YP_003080523.1 CDS yidI NC_013008.1 4706038 4706487 D inner membrane protein 4706038..4706487 Escherichia coli O157:H7 str. TW14359 8219295 YP_003080524.1 CDS yidJ NC_013008.1 4706534 4708027 R sulfatase/phosphatase complement(4706534..4708027) Escherichia coli O157:H7 str. TW14359 8219296 YP_003080525.1 CDS yidK NC_013008.1 4708024 4709739 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4708024..4709739) Escherichia coli O157:H7 str. TW14359 8219297 YP_003080526.1 CDS yidL NC_013008.1 4709876 4710799 D DNA-binding transcriptional regulator 4709876..4710799 Escherichia coli O157:H7 str. TW14359 8219298 YP_003080527.1 CDS ECSP_4733 NC_013008.1 4710796 4712118 R 6-phospho-beta-glucosidase complement(4710796..4712118) Escherichia coli O157:H7 str. TW14359 8219299 YP_003080528.1 CDS ECSP_4734 NC_013008.1 4712118 4713734 R PTS component complement(4712118..4713734) Escherichia coli O157:H7 str. TW14359 8219300 YP_003080529.1 CDS yidP NC_013008.1 4714030 4714746 D DNA-binding transcriptional regulator 4714030..4714746 Escherichia coli O157:H7 str. TW14359 8219301 YP_003080530.1 CDS yidE NC_013008.1 4714743 4716404 R hypothetical protein complement(4714743..4716404) Escherichia coli O157:H7 str. TW14359 8219302 YP_003080531.1 CDS ibpB NC_013008.1 4716600 4717028 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4716600..4717028) Escherichia coli O157:H7 str. TW14359 8219303 YP_003080532.1 CDS ibpA NC_013008.1 4717140 4717553 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4717140..4717553) Escherichia coli O157:H7 str. TW14359 8219304 YP_003080533.1 CDS yidQ NC_013008.1 4717859 4718191 D hypothetical protein 4717859..4718191 Escherichia coli O157:H7 str. TW14359 8219305 YP_003080534.1 CDS yidR NC_013008.1 4718193 4719407 R hypothetical protein complement(4718193..4719407) Escherichia coli O157:H7 str. TW14359 8219306 YP_003080535.1 CDS cbrA NC_013008.1 4719508 4720572 D FAD/NAD(P)-binding domain; oxidoreductase 4719508..4720572 Escherichia coli O157:H7 str. TW14359 8219307 YP_003080536.1 CDS yidX NC_013008.1 4720818 4721474 D hypothetical protein 4720818..4721474 Escherichia coli O157:H7 str. TW14359 8219308 YP_003080537.1 CDS yidA NC_013008.1 4721520 4722332 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4721520..4722332) Escherichia coli O157:H7 str. TW14359 8219309 YP_003080538.1 CDS yidB NC_013008.1 4722447 4722845 R hypothetical protein complement(4722447..4722845) Escherichia coli O157:H7 str. TW14359 8219310 YP_003080539.1 CDS gyrB NC_013008.1 4723085 4725499 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4723085..4725499) Escherichia coli O157:H7 str. TW14359 8219311 YP_003080540.1 CDS recF NC_013008.1 4725528 4726601 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4725528..4726601) Escherichia coli O157:H7 str. TW14359 8219312 YP_003080541.1 CDS dnaN NC_013008.1 4726601 4727701 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4726601..4727701) Escherichia coli O157:H7 str. TW14359 8219313 YP_003080542.1 CDS dnaA NC_013008.1 4727706 4729109 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4727706..4729109) Escherichia coli O157:H7 str. TW14359 8219314 YP_003080543.1 CDS rpmH NC_013008.1 4729716 4729856 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4729716..4729856 Escherichia coli O157:H7 str. TW14359 8219315 YP_003080544.1 CDS rnpA NC_013008.1 4729873 4730232 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4729873..4730232 Escherichia coli O157:H7 str. TW14359 8219316 YP_003080545.1 CDS yidC NC_013008.1 4730456 4732102 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4730456..4732102 Escherichia coli O157:H7 str. TW14359 8219317 YP_003080546.1 CDS trmE NC_013008.1 4732208 4733572 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4732208..4733572 Escherichia coli O157:H7 str. TW14359 8219318 YP_003080547.1 CDS ECSP_4753 NC_013008.1 4733722 4733943 R hypothetical protein complement(4733722..4733943) Escherichia coli O157:H7 str. TW14359 8219319 YP_003080548.1 CDS ECSP_4754 NC_013008.1 4733903 4735891 R protein with ShET2 enterotoxin, N-terminal region domain complement(4733903..4735891) Escherichia coli O157:H7 str. TW14359 8219320 YP_003080549.1 CDS tnaC NC_013008.1 4736282 4736356 D tryptophanase leader peptide 4736282..4736356 Escherichia coli O157:H7 str. TW14359 8219321 YP_003080550.1 CDS tnaA NC_013008.1 4736577 4737992 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4736577..4737992 Escherichia coli O157:H7 str. TW14359 8219322 YP_003080551.1 CDS tnaB NC_013008.1 4738083 4739330 D tryptophan transporter of low affinity; tryptophan permease TnaB 4738083..4739330 Escherichia coli O157:H7 str. TW14359 8219323 YP_003080552.1 CDS mdtL NC_013008.1 4739462 4740637 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4739462..4740637 Escherichia coli O157:H7 str. TW14359 8219324 YP_003080553.1 CDS yidZ NC_013008.1 4740612 4741571 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4740612..4741571 Escherichia coli O157:H7 str. TW14359 8219325 YP_003080554.1 CDS yieE NC_013008.1 4741728 4742477 D phosphopantetheinyl transferase 4741728..4742477 Escherichia coli O157:H7 str. TW14359 8219326 YP_003080555.1 CDS yieF NC_013008.1 4742499 4743065 D chromate reductase, Class I, flavoprotein 4742499..4743065 Escherichia coli O157:H7 str. TW14359 8219327 YP_003080556.1 CDS yieG NC_013008.1 4743119 4744456 R inner membrane protein complement(4743119..4744456) Escherichia coli O157:H7 str. TW14359 8219328 YP_003080557.1 CDS yieH NC_013008.1 4744622 4745287 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4744622..4745287 Escherichia coli O157:H7 str. TW14359 8219329 YP_003080558.1 CDS espY4 NC_013008.1 4745424 4747832 R non-LEE-encoded type III effector complement(4745424..4747832) Escherichia coli O157:H7 str. TW14359 8219330 YP_003080559.1 CDS phoU NC_013008.1 4752699 4753424 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4752699..4753424) Escherichia coli O157:H7 str. TW14359 8219332 YP_003080560.1 CDS pstB NC_013008.1 4753439 4754212 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4753439..4754212) Escherichia coli O157:H7 str. TW14359 8219333 YP_003080561.1 CDS pstA NC_013008.1 4754395 4755285 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4754395..4755285) Escherichia coli O157:H7 str. TW14359 8219334 YP_003080562.1 CDS pstC NC_013008.1 4755285 4756244 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4755285..4756244) Escherichia coli O157:H7 str. TW14359 8219335 YP_003080563.1 CDS pstS NC_013008.1 4756331 4757371 R phosphate ABC transporter substrate-binding protein complement(4756331..4757371) Escherichia coli O157:H7 str. TW14359 8219336 YP_003080564.1 CDS ECSP_4771 NC_013008.1 4757438 4757554 D hypothetical protein 4757438..4757554 Escherichia coli O157:H7 str. TW14359 8219337 YP_003080565.1 CDS ECSP_4772 NC_013008.1 4757583 4758665 R fimbrial protein complement(4757583..4758665) Escherichia coli O157:H7 str. TW14359 8219338 YP_003080566.1 CDS lpfD2 NC_013008.1 4758693 4759763 R fimbrial protein complement(4758693..4759763) Escherichia coli O157:H7 str. TW14359 8219339 YP_003080567.1 CDS lpfC NC_013008.1 4759775 4762309 R fimbrial usher complement(4759775..4762309) Escherichia coli O157:H7 str. TW14359 8219340 YP_003080568.1 CDS ECSP_4775 NC_013008.1 4762331 4762492 R fimbrial chaperone complement(4762331..4762492) Escherichia coli O157:H7 str. TW14359 8219341 YP_003080569.1 CDS lpfB2 NC_013008.1 4762633 4763016 R fimbrial chaperone complement(4762633..4763016) Escherichia coli O157:H7 str. TW14359 8219342 YP_003080570.1 CDS lpfA2 NC_013008.1 4763120 4763722 R major fimbrial subunit complement(4763120..4763722) Escherichia coli O157:H7 str. TW14359 8219343 YP_003080572.1 CDS glmS NC_013008.1 4764422 4766251 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4764422..4766251) Escherichia coli O157:H7 str. TW14359 8219345 YP_003080573.1 CDS glmU NC_013008.1 4766413 4767783 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4766413..4767783) Escherichia coli O157:H7 str. TW14359 8219346 YP_003080574.1 CDS atpC NC_013008.1 4768135 4768554 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(4768135..4768554) Escherichia coli O157:H7 str. TW14359 8219347 YP_003080575.1 CDS atpD NC_013008.1 4768575 4769957 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(4768575..4769957) Escherichia coli O157:H7 str. TW14359 8219348 YP_003080576.1 CDS atpG NC_013008.1 4769984 4770847 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(4769984..4770847) Escherichia coli O157:H7 str. TW14359 8219349 YP_003080577.1 CDS atpA NC_013008.1 4770898 4772439 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(4770898..4772439) Escherichia coli O157:H7 str. TW14359 8219350 YP_003080578.1 CDS atpH NC_013008.1 4772452 4772985 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(4772452..4772985) Escherichia coli O157:H7 str. TW14359 8219351 YP_003080579.1 CDS atpF NC_013008.1 4773000 4773470 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(4773000..4773470) Escherichia coli O157:H7 str. TW14359 8219352 YP_003080580.1 CDS atpE NC_013008.1 4773532 4773771 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(4773532..4773771) Escherichia coli O157:H7 str. TW14359 8219353 YP_003080581.1 CDS atpB NC_013008.1 4773818 4774633 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(4773818..4774633) Escherichia coli O157:H7 str. TW14359 8219354 YP_003080582.1 CDS atpI NC_013008.1 4774642 4775022 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4774642..4775022) Escherichia coli O157:H7 str. TW14359 8219355 YP_003080583.1 CDS gidB NC_013008.1 4775639 4776262 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4775639..4776262) Escherichia coli O157:H7 str. TW14359 8219356 YP_003080584.1 CDS gidA NC_013008.1 4776326 4778215 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(4776326..4778215) Escherichia coli O157:H7 str. TW14359 8219357 YP_003080585.1 CDS mioC NC_013008.1 4778594 4779037 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4778594..4779037) Escherichia coli O157:H7 str. TW14359 8219358 YP_003080586.1 CDS asnC NC_013008.1 4779127 4779585 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4779127..4779585) Escherichia coli O157:H7 str. TW14359 8219359 YP_003080587.1 CDS asnA NC_013008.1 4779737 4780729 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4779737..4780729 Escherichia coli O157:H7 str. TW14359 8219360 YP_003080588.1 CDS yieM NC_013008.1 4780734 4782185 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4780734..4782185) Escherichia coli O157:H7 str. TW14359 8219361 YP_003080589.1 CDS ravA NC_013008.1 4782179 4783675 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4782179..4783675) Escherichia coli O157:H7 str. TW14359 8219362 YP_003080590.1 CDS trkD NC_013008.1 4783898 4785766 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4783898..4785766 Escherichia coli O157:H7 str. TW14359 8219363 YP_003080591.1 CDS rbsD NC_013008.1 4785933 4786352 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4785933..4786352 Escherichia coli O157:H7 str. TW14359 8219364 YP_003080592.1 CDS rbsA NC_013008.1 4786360 4787865 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4786360..4787865 Escherichia coli O157:H7 str. TW14359 8219365 YP_003080593.1 CDS rbsC NC_013008.1 4787870 4788835 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4787870..4788835 Escherichia coli O157:H7 str. TW14359 8219366 YP_003080594.1 CDS rbsB NC_013008.1 4788860 4789750 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4788860..4789750 Escherichia coli O157:H7 str. TW14359 8219367 YP_003080595.1 CDS rbsK NC_013008.1 4789876 4790805 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4789876..4790805 Escherichia coli O157:H7 str. TW14359 8219368 YP_003080596.1 CDS rbsR NC_013008.1 4790809 4791801 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4790809..4791801 Escherichia coli O157:H7 str. TW14359 8219369 YP_003080597.1 CDS hsrA NC_013008.1 4791767 4793194 R multidrug or homocysteine efflux system complement(4791767..4793194) Escherichia coli O157:H7 str. TW14359 8219370 YP_003080598.1 CDS yieP NC_013008.1 4793217 4793909 R transcriptional regulator complement(4793217..4793909) Escherichia coli O157:H7 str. TW14359 8219371 YP_003080599.1 CDS ECSP_4806 NC_013008.1 4794132 4794245 R hypothetical protein complement(4794132..4794245) Escherichia coli O157:H7 str. TW14359 8219372 YP_003080600.1 CDS hdfR NC_013008.1 4799711 4800550 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4799711..4800550) Escherichia coli O157:H7 str. TW14359 8219379 YP_003080601.1 CDS yifE NC_013008.1 4800669 4801007 D hypothetical protein 4800669..4801007 Escherichia coli O157:H7 str. TW14359 8219380 YP_003080602.1 CDS yifB NC_013008.1 4801031 4802551 R among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4801031..4802551) Escherichia coli O157:H7 str. TW14359 8219381 YP_003080603.1 CDS ilvL NC_013008.1 4802904 4803002 D ilvG operon leader peptide 4802904..4803002 Escherichia coli O157:H7 str. TW14359 8219382 YP_003080604.1 CDS ilvG NC_013008.1 4803142 4804788 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4803142..4804788 Escherichia coli O157:H7 str. TW14359 8219383 YP_003080605.1 CDS ilvM NC_013008.1 4804785 4805048 D acetolactate synthase 2 regulatory subunit 4804785..4805048 Escherichia coli O157:H7 str. TW14359 8219384 YP_003080606.1 CDS ilvE NC_013008.1 4805068 4805997 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4805068..4805997 Escherichia coli O157:H7 str. TW14359 8219385 YP_003080607.1 CDS ilvD NC_013008.1 4806062 4807912 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4806062..4807912 Escherichia coli O157:H7 str. TW14359 8219386 YP_003080608.1 CDS ilvA NC_013008.1 4807915 4809459 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4807915..4809459 Escherichia coli O157:H7 str. TW14359 8219387 YP_003080609.1 CDS ilvY NC_013008.1 4809511 4810404 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4809511..4810404) Escherichia coli O157:H7 str. TW14359 8219388 YP_003080610.1 CDS ilvC NC_013008.1 4810554 4812029 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4810554..4812029 Escherichia coli O157:H7 str. TW14359 8219389 YP_003080611.1 CDS ppiC NC_013008.1 4812075 4812356 R peptidyl-prolyl cis-trans isomerase C complement(4812075..4812356) Escherichia coli O157:H7 str. TW14359 8219390 YP_003080612.1 CDS yifN NC_013008.1 4812555 4813004 R hypothetical protein complement(4812555..4813004) Escherichia coli O157:H7 str. TW14359 8219391 YP_003080613.1 CDS rep NC_013008.1 4813221 4815242 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4813221..4815242 Escherichia coli O157:H7 str. TW14359 8219392 YP_003080614.1 CDS gpp NC_013008.1 4815289 4816773 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4815289..4816773) Escherichia coli O157:H7 str. TW14359 8219393 YP_003080615.1 CDS rhlB NC_013008.1 4816909 4818174 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4816909..4818174) Escherichia coli O157:H7 str. TW14359 8219394 YP_003080616.1 CDS trxA NC_013008.1 4818305 4818634 D thioredoxin 4818305..4818634 Escherichia coli O157:H7 str. TW14359 8219395 YP_003080617.1 CDS rho NC_013008.1 4818961 4820220 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4818961..4820220 Escherichia coli O157:H7 str. TW14359 8219396 YP_003080618.1 CDS ECSP_4831 NC_013008.1 4820230 4820448 D hypothetical protein 4820230..4820448 Escherichia coli O157:H7 str. TW14359 8219397 YP_003080619.1 CDS rfe NC_013008.1 4820460 4821563 D UDP-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 4820460..4821563 Escherichia coli O157:H7 str. TW14359 8219398 YP_003080620.1 CDS wzzE NC_013008.1 4821575 4822621 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4821575..4822621 Escherichia coli O157:H7 str. TW14359 8219399 YP_003080621.1 CDS rffE NC_013008.1 4822677 4823807 D UDP-N-acetyl glucosamine-2-epimerase 4822677..4823807 Escherichia coli O157:H7 str. TW14359 8219400 YP_003080622.1 CDS wecC NC_013008.1 4823804 4825066 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4823804..4825066 Escherichia coli O157:H7 str. TW14359 8219401 YP_003080623.1 CDS rffG NC_013008.1 4825066 4826133 D dTDP-glucose 4,6-dehydratase 4825066..4826133 Escherichia coli O157:H7 str. TW14359 8219402 YP_003080624.1 CDS rffH NC_013008.1 4826152 4827033 D glucose-1-phosphate thymidylyltransferase 4826152..4827033 Escherichia coli O157:H7 str. TW14359 8219403 YP_003080625.1 CDS rffC NC_013008.1 4827011 4827685 D TDP-fucosamine acetyltransferase 4827011..4827685 Escherichia coli O157:H7 str. TW14359 8219404 YP_003080626.1 CDS rffA NC_013008.1 4827690 4828820 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4827690..4828820 Escherichia coli O157:H7 str. TW14359 8219405 YP_003080627.1 CDS wzxE NC_013008.1 4828822 4830072 D lipid III translocase 4828822..4830072 Escherichia coli O157:H7 str. TW14359 8219406 YP_003080628.1 CDS rffT NC_013008.1 4830069 4831148 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4830069..4831148 Escherichia coli O157:H7 str. TW14359 8219407 YP_003080629.1 CDS ECSP_4842 NC_013008.1 4831145 4832497 D enterobacterial common antigen polymerase; common antigen polymerase 4831145..4832497 Escherichia coli O157:H7 str. TW14359 8219408 YP_003080630.1 CDS ECSP_4843 NC_013008.1 4832500 4833240 D UDP-N-acetyl-D-mannosaminuronic acid transferase 4832500..4833240 Escherichia coli O157:H7 str. TW14359 8219409 YP_003080631.1 CDS yifK NC_013008.1 4833431 4834816 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4833431..4834816 Escherichia coli O157:H7 str. TW14359 8219410 YP_003080632.1 CDS aslB NC_013008.1 4835728 4836963 D regulator of arylsulfatase activity 4835728..4836963 Escherichia coli O157:H7 str. TW14359 8219417 YP_003080633.1 CDS aslA NC_013008.1 4837131 4838786 R acrylsulfatase-like enzyme complement(4837131..4838786) Escherichia coli O157:H7 str. TW14359 8219418 YP_003080634.1 CDS ECSP_4853 NC_013008.1 4838929 4839066 R hypothetical protein complement(4838929..4839066) Escherichia coli O157:H7 str. TW14359 8219419 YP_003080635.1 CDS hemY NC_013008.1 4839465 4840661 R protoheme IX biogenesis protein complement(4839465..4840661) Escherichia coli O157:H7 str. TW14359 8219420 YP_003080636.1 CDS hemX NC_013008.1 4840664 4841899 R uroporphyrinogen III C-methyltransferase complement(4840664..4841899) Escherichia coli O157:H7 str. TW14359 8219421 YP_003080637.1 CDS hemD NC_013008.1 4841921 4842661 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4841921..4842661) Escherichia coli O157:H7 str. TW14359 8219422 YP_003080638.1 CDS hemC NC_013008.1 4842658 4843599 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4842658..4843599) Escherichia coli O157:H7 str. TW14359 8219423 YP_003080639.1 CDS cyaA NC_013008.1 4843986 4846532 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4843986..4846532 Escherichia coli O157:H7 str. TW14359 8219424 YP_003080640.1 CDS cyaY NC_013008.1 4846572 4846892 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4846572..4846892) Escherichia coli O157:H7 str. TW14359 8219425 YP_003080641.1 CDS yifL NC_013008.1 4847355 4847558 D lipoprotein 4847355..4847558 Escherichia coli O157:H7 str. TW14359 8219426 YP_003080642.1 CDS dapF NC_013008.1 4847595 4848419 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4847595..4848419 Escherichia coli O157:H7 str. TW14359 8219427 YP_003080643.1 CDS yigA NC_013008.1 4848416 4849123 D hypothetical protein 4848416..4849123 Escherichia coli O157:H7 str. TW14359 8219428 YP_003080644.1 CDS xerC NC_013008.1 4849120 4850016 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4849120..4850016 Escherichia coli O157:H7 str. TW14359 8219429 YP_003080645.1 CDS yigB NC_013008.1 4850016 4850732 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4850016..4850732 Escherichia coli O157:H7 str. TW14359 8219430 YP_003080646.1 CDS uvrD NC_013008.1 4850816 4852978 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4850816..4852978 Escherichia coli O157:H7 str. TW14359 8219431 YP_003080647.1 CDS ECSP_4866 NC_013008.1 4853023 4853925 R hypothetical protein complement(4853023..4853925) Escherichia coli O157:H7 str. TW14359 8219432 YP_003080648.1 CDS yigE NC_013008.1 4854008 4854772 R hypothetical protein complement(4854008..4854772) Escherichia coli O157:H7 str. TW14359 8219433 YP_003080649.1 CDS corA NC_013008.1 4855142 4856092 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4855142..4856092 Escherichia coli O157:H7 str. TW14359 8219434 YP_003080650.1 CDS ECSP_4869 NC_013008.1 4856134 4856625 R hypothetical protein complement(4856134..4856625) Escherichia coli O157:H7 str. TW14359 8219435 YP_003080651.1 CDS ECSP_4870 NC_013008.1 4856622 4857470 R hypothetical protein complement(4856622..4857470) Escherichia coli O157:H7 str. TW14359 8219436 YP_003080652.1 CDS ECSP_4872 NC_013008.1 4857828 4858214 R hypothetical protein complement(4857828..4858214) Escherichia coli O157:H7 str. TW14359 8219438 YP_003080653.1 CDS ECSP_4873 NC_013008.1 4858430 4858729 D hypothetical protein 4858430..4858729 Escherichia coli O157:H7 str. TW14359 8219439 YP_003080654.1 CDS rarD NC_013008.1 4858776 4859663 R chloramphenical resistance permease complement(4858776..4859663) Escherichia coli O157:H7 str. TW14359 8219440 YP_003080655.1 CDS yigI NC_013008.1 4859715 4860182 R hypothetical protein complement(4859715..4860182) Escherichia coli O157:H7 str. TW14359 8219441 YP_003080656.1 CDS pldA NC_013008.1 4860347 4861216 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4860347..4861216 Escherichia coli O157:H7 str. TW14359 8219442 YP_003080657.1 CDS recQ NC_013008.1 4861349 4863178 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4861349..4863178 Escherichia coli O157:H7 str. TW14359 8219443 YP_003080658.1 CDS rhtC NC_013008.1 4863242 4863862 D threonine efflux system 4863242..4863862 Escherichia coli O157:H7 str. TW14359 8219444 YP_003080659.1 CDS rhtB NC_013008.1 4863924 4864544 R homoserine/homoserine lactone efflux protein complement(4863924..4864544) Escherichia coli O157:H7 str. TW14359 8219445 YP_003080660.1 CDS pldB NC_013008.1 4864655 4865677 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4864655..4865677 Escherichia coli O157:H7 str. TW14359 8219446 YP_003080661.1 CDS yigL NC_013008.1 4865685 4866485 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4865685..4866485 Escherichia coli O157:H7 str. TW14359 8219447 YP_003080662.1 CDS yigM NC_013008.1 4866561 4867460 D inner membrane protein 4866561..4867460 Escherichia coli O157:H7 str. TW14359 8219448 YP_003080663.1 CDS metR NC_013008.1 4867348 4868301 R DNA-binding transcriptional activator, homocysteine-binding complement(4867348..4868301) Escherichia coli O157:H7 str. TW14359 8219449 YP_003080664.1 CDS metE NC_013008.1 4868537 4870798 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4868537..4870798 Escherichia coli O157:H7 str. TW14359 8219450 YP_003080665.1 CDS ysgA NC_013008.1 4870838 4871653 R hydrolase complement(4870838..4871653) Escherichia coli O157:H7 str. TW14359 8219451 YP_003080666.1 CDS udp NC_013008.1 4871915 4872676 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4871915..4872676 Escherichia coli O157:H7 str. TW14359 8219452 YP_003080667.1 CDS rmuC NC_013008.1 4872817 4874244 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4872817..4874244 Escherichia coli O157:H7 str. TW14359 8219453 YP_003080668.1 CDS ubiE NC_013008.1 4874339 4875094 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4874339..4875094 Escherichia coli O157:H7 str. TW14359 8219454 YP_003080669.1 CDS yigP NC_013008.1 4875108 4875713 D hypothetical protein 4875108..4875713 Escherichia coli O157:H7 str. TW14359 8219455 YP_003080670.1 CDS ubiB NC_013008.1 4875710 4877350 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4875710..4877350 Escherichia coli O157:H7 str. TW14359 8219456 YP_003080671.1 CDS tatA NC_013008.1 4877429 4877698 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4877429..4877698 Escherichia coli O157:H7 str. TW14359 8219457 YP_003080672.1 CDS tatB NC_013008.1 4877702 4878217 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4877702..4878217 Escherichia coli O157:H7 str. TW14359 8219458 YP_003080673.1 CDS tatC NC_013008.1 4878220 4878996 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4878220..4878996 Escherichia coli O157:H7 str. TW14359 8219459 YP_003080674.1 CDS tatD NC_013008.1 4879038 4879820 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4879038..4879820 Escherichia coli O157:H7 str. TW14359 8219460 YP_003080675.1 CDS rfaH NC_013008.1 4879817 4880305 R transcriptional activator RfaH complement(4879817..4880305) Escherichia coli O157:H7 str. TW14359 8219461 YP_003080676.1 CDS ubiD NC_013008.1 4880472 4881965 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4880472..4881965 Escherichia coli O157:H7 str. TW14359 8219462 YP_003080677.1 CDS fre NC_013008.1 4882011 4882712 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4882011..4882712 Escherichia coli O157:H7 str. TW14359 8219463 YP_003080678.1 CDS fadA NC_013008.1 4882904 4884067 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4882904..4884067) Escherichia coli O157:H7 str. TW14359 8219464 YP_003080679.1 CDS fadB NC_013008.1 4884077 4886266 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4884077..4886266) Escherichia coli O157:H7 str. TW14359 8219465 YP_003080680.1 CDS pepQ NC_013008.1 4886456 4887787 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4886456..4887787 Escherichia coli O157:H7 str. TW14359 8219466 YP_003080681.1 CDS yigZ NC_013008.1 4887787 4888401 D hypothetical protein 4887787..4888401 Escherichia coli O157:H7 str. TW14359 8219467 YP_003080682.1 CDS trkH NC_013008.1 4888440 4889891 D potassium transporter 4888440..4889891 Escherichia coli O157:H7 str. TW14359 8219468 YP_003080683.1 CDS hemG NC_013008.1 4889903 4890448 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4889903..4890448 Escherichia coli O157:H7 str. TW14359 8219469 YP_003080684.1 CDS mobB NC_013008.1 4896033 4896560 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4896033..4896560) Escherichia coli O157:H7 str. TW14359 8219475 YP_003080685.1 CDS mobA NC_013008.1 4896542 4897126 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4896542..4897126) Escherichia coli O157:H7 str. TW14359 8219476 YP_003080686.1 CDS yihD NC_013008.1 4897196 4897465 D hypothetical protein 4897196..4897465 Escherichia coli O157:H7 str. TW14359 8219477 YP_003080687.1 CDS rdoA NC_013008.1 4897542 4898528 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4897542..4898528 Escherichia coli O157:H7 str. TW14359 8219478 YP_003080688.1 CDS dsbA NC_013008.1 4898545 4899171 D periplasmic protein disulfide isomerase I 4898545..4899171 Escherichia coli O157:H7 str. TW14359 8219479 YP_003080689.1 CDS yihF NC_013008.1 4899326 4900756 D hypothetical protein 4899326..4900756 Escherichia coli O157:H7 str. TW14359 8219480 YP_003080690.1 CDS yihG NC_013008.1 4900797 4901729 R acyltransferase complement(4900797..4901729) Escherichia coli O157:H7 str. TW14359 8219481 YP_003080691.1 CDS polA NC_013008.1 4902093 4904879 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4902093..4904879 Escherichia coli O157:H7 str. TW14359 8219482 YP_003080692.1 CDS engB NC_013008.1 4905261 4905893 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4905261..4905893) Escherichia coli O157:H7 str. TW14359 8219483 YP_003080694.1 CDS yihI NC_013008.1 4906475 4906981 D hypothetical protein 4906475..4906981 Escherichia coli O157:H7 str. TW14359 8219485 YP_003080695.1 CDS hemN NC_013008.1 4907170 4908543 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4907170..4908543 Escherichia coli O157:H7 str. TW14359 8219486 YP_003080696.1 CDS ECSP_4921 NC_013008.1 4908636 4908749 R hypothetical protein complement(4908636..4908749) Escherichia coli O157:H7 str. TW14359 8219487 YP_003080697.1 CDS ECSP_4922 NC_013008.1 4908733 4908843 R hypothetical protein complement(4908733..4908843) Escherichia coli O157:H7 str. TW14359 8219488 YP_003080698.1 CDS glnG NC_013008.1 4908955 4910364 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4908955..4910364) Escherichia coli O157:H7 str. TW14359 8219489 YP_003080699.1 CDS glnL NC_013008.1 4910376 4911425 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4910376..4911425) Escherichia coli O157:H7 str. TW14359 8219490 YP_003080700.1 CDS glnA NC_013008.1 4911599 4913008 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4911599..4913008) Escherichia coli O157:H7 str. TW14359 8219491 YP_003080701.1 CDS bipA NC_013008.1 4913381 4915204 D GTP-binding protein 4913381..4915204 Escherichia coli O157:H7 str. TW14359 8219492 YP_003080702.1 CDS yihL NC_013008.1 4915421 4916131 D DNA-binding transcriptional regulator 4915421..4916131 Escherichia coli O157:H7 str. TW14359 8219493 YP_003080703.1 CDS yihM NC_013008.1 4916139 4917119 D sugar phosphate isomerase 4916139..4917119 Escherichia coli O157:H7 str. TW14359 8219494 YP_003080704.1 CDS yihN NC_013008.1 4917221 4918486 D transporter 4917221..4918486 Escherichia coli O157:H7 str. TW14359 8219495 YP_003080705.1 CDS ompL NC_013008.1 4918577 4919269 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(4918577..4919269) Escherichia coli O157:H7 str. TW14359 8219496 YP_003080706.1 CDS yihO NC_013008.1 4919336 4920739 R predited transporter complement(4919336..4920739) Escherichia coli O157:H7 str. TW14359 8219497 YP_003080707.1 CDS yihP NC_013008.1 4920779 4922164 R transporter complement(4920779..4922164) Escherichia coli O157:H7 str. TW14359 8219498 YP_003080708.1 CDS yihQ NC_013008.1 4922210 4924246 R alpha-glucosidase complement(4922210..4924246) Escherichia coli O157:H7 str. TW14359 8219499 YP_003080709.1 CDS ECSP_4934 NC_013008.1 4924354 4925229 R hypothetical protein complement(4924354..4925229) Escherichia coli O157:H7 str. TW14359 8219500 YP_003080710.1 CDS yihR NC_013008.1 4925290 4926192 R aldose-1-epimerase complement(4925290..4926192) Escherichia coli O157:H7 str. TW14359 8219501 YP_003080711.1 CDS yihS NC_013008.1 4926259 4927500 R glucosamine isomerase complement(4926259..4927500) Escherichia coli O157:H7 str. TW14359 8219502 YP_003080712.1 CDS yihT NC_013008.1 4927516 4928394 R aldolase complement(4927516..4928394) Escherichia coli O157:H7 str. TW14359 8219503 YP_003080713.1 CDS yihU NC_013008.1 4928418 4929314 R oxidoreductase complement(4928418..4929314) Escherichia coli O157:H7 str. TW14359 8219504 YP_003080714.1 CDS yihV NC_013008.1 4929482 4930378 D sugar kinase 4929482..4930378 Escherichia coli O157:H7 str. TW14359 8219505 YP_003080715.1 CDS yihW NC_013008.1 4930412 4931197 D DNA-binding transcriptional regulator 4930412..4931197 Escherichia coli O157:H7 str. TW14359 8219506 YP_003080716.1 CDS yihX NC_013008.1 4931296 4931895 D phosphatase 4931296..4931895 Escherichia coli O157:H7 str. TW14359 8219507 YP_003080717.1 CDS rbn NC_013008.1 4931889 4932761 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4931889..4932761 Escherichia coli O157:H7 str. TW14359 8219508 YP_003080718.1 CDS dtd NC_013008.1 4932758 4933195 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4932758..4933195 Escherichia coli O157:H7 str. TW14359 8219509 YP_003080719.1 CDS yiiD NC_013008.1 4933192 4934181 D acetyltransferase 4933192..4934181 Escherichia coli O157:H7 str. TW14359 8219510 YP_003080720.1 CDS ECSP_4946 NC_013008.1 4936799 4936915 R hypothetical protein complement(4936799..4936915) Escherichia coli O157:H7 str. TW14359 8219512 YP_003080721.1 CDS yiiE NC_013008.1 4937100 4937318 D transcriptional regulator 4937100..4937318 Escherichia coli O157:H7 str. TW14359 8219513 YP_003080722.1 CDS yiiF NC_013008.1 4937559 4937777 D hypothetical protein 4937559..4937777 Escherichia coli O157:H7 str. TW14359 8219514 YP_003080723.1 CDS fdhE NC_013008.1 4938107 4939036 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4938107..4939036) Escherichia coli O157:H7 str. TW14359 8219515 YP_003080724.1 CDS fdoI NC_013008.1 4939033 4939668 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4939033..4939668) Escherichia coli O157:H7 str. TW14359 8219516 YP_003080725.1 CDS fdoH NC_013008.1 4939665 4940567 R formate dehydrogenase-O, Fe-S subunit complement(4939665..4940567) Escherichia coli O157:H7 str. TW14359 8219517 YP_003080726.1 CDS fdoG NC_013008.1 4940580 4942994 R formate dehydrogenase-O, large subunit complement(4940580..4942994) Escherichia coli O157:H7 str. TW14359 8219518 YP_003080727.1 CDS ECSP_4953 NC_013008.1 4943043 4943630 R formate dehydrogenase-O, large subunit complement(4943043..4943630) Escherichia coli O157:H7 str. TW14359 8219519 YP_003080728.1 CDS fdhD NC_013008.1 4943824 4944657 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4943824..4944657 Escherichia coli O157:H7 str. TW14359 8219520 YP_003080729.1 CDS ECSP_4955 NC_013008.1 4944707 4944814 D hypothetical protein 4944707..4944814 Escherichia coli O157:H7 str. TW14359 8219521 YP_003080730.1 CDS yiiG NC_013008.1 4944811 4945866 D hypothetical protein 4944811..4945866 Escherichia coli O157:H7 str. TW14359 8219522 YP_003080731.1 CDS frvR NC_013008.1 4945916 4947664 R repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein complement(4945916..4947664) Escherichia coli O157:H7 str. TW14359 8219523 YP_003080732.1 CDS frvX NC_013008.1 4947664 4948734 R with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX complement(4947664..4948734) Escherichia coli O157:H7 str. TW14359 8219524 YP_003080733.1 CDS frvB NC_013008.1 4948724 4950163 R PTS system transporter subunits IIBC complement(4948724..4950163) Escherichia coli O157:H7 str. TW14359 8219525 YP_003080734.1 CDS frvA NC_013008.1 4950174 4950620 R with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA complement(4950174..4950620) Escherichia coli O157:H7 str. TW14359 8219526 YP_003080735.1 CDS ECSP_4961 NC_013008.1 4951098 4952492 D glycoporin 4951098..4952492 Escherichia coli O157:H7 str. TW14359 8219527 YP_003080736.1 CDS rhaM NC_013008.1 4952533 4952847 R L-rhamnose mutarotase complement(4952533..4952847) Escherichia coli O157:H7 str. TW14359 8219528 YP_003080737.1 CDS rhaD NC_013008.1 4952857 4953681 R rhamnulose-1-phosphate aldolase complement(4952857..4953681) Escherichia coli O157:H7 str. TW14359 8219529 YP_003080738.1 CDS rhaA NC_013008.1 4953856 4955115 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4953856..4955115) Escherichia coli O157:H7 str. TW14359 8219530 YP_003080739.1 CDS rhaB NC_013008.1 4955112 4956581 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4955112..4956581) Escherichia coli O157:H7 str. TW14359 8219531 YP_003080740.1 CDS ECSP_4966 NC_013008.1 4956660 4956809 D hypothetical protein 4956660..4956809 Escherichia coli O157:H7 str. TW14359 8219532 YP_003080741.1 CDS rhaS NC_013008.1 4956869 4957705 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4956869..4957705 Escherichia coli O157:H7 str. TW14359 8219533 YP_003080742.1 CDS rhaR NC_013008.1 4957779 4958627 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4957779..4958627 Escherichia coli O157:H7 str. TW14359 8219534 YP_003080743.1 CDS rhaT NC_013008.1 4958624 4959415 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4958624..4959415) Escherichia coli O157:H7 str. TW14359 8219535 YP_003080744.1 CDS ECSP_4970 NC_013008.1 4959506 4959658 R hypothetical protein complement(4959506..4959658) Escherichia coli O157:H7 str. TW14359 8219536 YP_003080745.1 CDS sodA NC_013008.1 4959943 4960563 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4959943..4960563 Escherichia coli O157:H7 str. TW14359 8219537 YP_003080746.1 CDS kdgT NC_013008.1 4960823 4961806 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4960823..4961806 Escherichia coli O157:H7 str. TW14359 8219538 YP_003080747.1 CDS yiiM NC_013008.1 4961955 4962629 D hypothetical protein 4961955..4962629 Escherichia coli O157:H7 str. TW14359 8219539 YP_003080748.1 CDS cpxA NC_013008.1 4962735 4964108 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4962735..4964108) Escherichia coli O157:H7 str. TW14359 8219540 YP_003080749.1 CDS cpxR NC_013008.1 4964105 4964803 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4964105..4964803) Escherichia coli O157:H7 str. TW14359 8219541 YP_003080750.1 CDS cpxP NC_013008.1 4964953 4965453 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4964953..4965453 Escherichia coli O157:H7 str. TW14359 8219542 YP_003080751.1 CDS fieF NC_013008.1 4965602 4966504 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4965602..4966504 Escherichia coli O157:H7 str. TW14359 8219543 YP_003080752.1 CDS pfkA NC_013008.1 4966685 4967647 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4966685..4967647 Escherichia coli O157:H7 str. TW14359 8219544 YP_003080753.1 CDS ECSP_4979 NC_013008.1 4967756 4967938 R hypothetical protein complement(4967756..4967938) Escherichia coli O157:H7 str. TW14359 8219545 YP_003080754.1 CDS sbp NC_013008.1 4967966 4968955 D sulfate transporter subunit 4967966..4968955 Escherichia coli O157:H7 str. TW14359 8219546 YP_003080755.1 CDS cdh NC_013008.1 4969062 4969817 D CDP-diacylglycerol pyrophosphatase 4969062..4969817 Escherichia coli O157:H7 str. TW14359 8219547 YP_003080756.1 CDS tpiA NC_013008.1 4969872 4970639 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4969872..4970639) Escherichia coli O157:H7 str. TW14359 8219548 YP_003080757.1 CDS yiiQ NC_013008.1 4970747 4971346 R hypothetical protein complement(4970747..4971346) Escherichia coli O157:H7 str. TW14359 8219549 YP_003080758.1 CDS yiiR NC_013008.1 4971447 4971887 D hypothetical protein 4971447..4971887 Escherichia coli O157:H7 str. TW14359 8219550 YP_003080759.1 CDS yiiS NC_013008.1 4972099 4972398 D hypothetical protein 4972099..4972398 Escherichia coli O157:H7 str. TW14359 8219551 YP_003080760.1 CDS yiiT NC_013008.1 4972425 4972853 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4972425..4972853 Escherichia coli O157:H7 str. TW14359 8219552 YP_003080761.1 CDS fpr NC_013008.1 4972858 4973604 R ferredoxin-NADP reductase complement(4972858..4973604) Escherichia coli O157:H7 str. TW14359 8219553 YP_003080762.1 CDS glpX NC_013008.1 4973701 4974711 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4973701..4974711) Escherichia coli O157:H7 str. TW14359 8219554 YP_003080763.1 CDS glpK NC_013008.1 4974941 4976449 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4974941..4976449) Escherichia coli O157:H7 str. TW14359 8219555 YP_003080764.1 CDS glpF NC_013008.1 4976472 4977317 R glycerol facilitator complement(4976472..4977317) Escherichia coli O157:H7 str. TW14359 8219556 YP_003080765.1 CDS yiiU NC_013008.1 4977743 4977988 D hypothetical protein 4977743..4977988 Escherichia coli O157:H7 str. TW14359 8219557 YP_003080766.1 CDS ECSP_4992 NC_013008.1 4978027 4978743 R hypothetical protein complement(4978027..4978743) Escherichia coli O157:H7 str. TW14359 8219558 YP_003080767.1 CDS ECSP_4993 NC_013008.1 4978776 4979450 R hypothetical protein complement(4978776..4979450) Escherichia coli O157:H7 str. TW14359 8219559 YP_003080768.1 CDS rraA NC_013008.1 4979510 4979995 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4979510..4979995) Escherichia coli O157:H7 str. TW14359 8219560 YP_003080769.1 CDS menA NC_013008.1 4980088 4981014 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4980088..4981014) Escherichia coli O157:H7 str. TW14359 8219561 YP_003080770.1 CDS hslU NC_013008.1 4981081 4982412 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4981081..4982412) Escherichia coli O157:H7 str. TW14359 8219562 YP_003080771.1 CDS hslV NC_013008.1 4982422 4982952 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4982422..4982952) Escherichia coli O157:H7 str. TW14359 8219563 YP_003080772.1 CDS ftsN NC_013008.1 4983045 4984004 R essential cell division protein FtsN complement(4983045..4984004) Escherichia coli O157:H7 str. TW14359 8219564 YP_003080773.1 CDS cytR NC_013008.1 4984096 4985121 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4984096..4985121) Escherichia coli O157:H7 str. TW14359 8219565 YP_003080774.1 CDS priA NC_013008.1 4985277 4987475 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4985277..4987475) Escherichia coli O157:H7 str. TW14359 8219566 YP_003080775.1 CDS rpmE NC_013008.1 4987678 4987890 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4987678..4987890 Escherichia coli O157:H7 str. TW14359 8219567 YP_003080776.1 CDS ECSP_5002 NC_013008.1 4989277 4992234 D hypothetical protein 4989277..4992234 Escherichia coli O157:H7 str. TW14359 8219568 YP_003080777.1 CDS ECSP_5003 NC_013008.1 4992236 4992472 D hypothetical protein 4992236..4992472 Escherichia coli O157:H7 str. TW14359 8219569 YP_003080778.1 CDS ECSP_5004 NC_013008.1 4992525 4992803 D hypothetical protein 4992525..4992803 Escherichia coli O157:H7 str. TW14359 8219570 YP_003080779.1 CDS ECSP_5006 NC_013008.1 4993048 4993320 R IS1 insertion element protein complement(4993048..4993320) Escherichia coli O157:H7 str. TW14359 8219572 YP_003080780.1 CDS yiiX NC_013008.1 4993465 4994073 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4993465..4994073) Escherichia coli O157:H7 str. TW14359 8219573 YP_003080781.1 CDS metJ NC_013008.1 4994133 4994450 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4994133..4994450) Escherichia coli O157:H7 str. TW14359 8219574 YP_003080782.1 CDS metB NC_013008.1 4994727 4995887 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4994727..4995887 Escherichia coli O157:H7 str. TW14359 8219575 YP_003080783.1 CDS metL NC_013008.1 4995890 4998322 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4995890..4998322 Escherichia coli O157:H7 str. TW14359 8219576 YP_003080784.1 CDS metF NC_013008.1 4998671 4999561 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4998671..4999561 Escherichia coli O157:H7 str. TW14359 8219577 YP_003080785.1 CDS katG NC_013008.1 4999890 5002070 D catalase/hydroperoxidase HPI(I) 4999890..5002070 Escherichia coli O157:H7 str. TW14359 8219578 YP_003080786.1 CDS yijE NC_013008.1 5002164 5003069 D permease 5002164..5003069 Escherichia coli O157:H7 str. TW14359 8219579 YP_003080787.1 CDS yijF NC_013008.1 5003096 5003713 R hypothetical protein complement(5003096..5003713) Escherichia coli O157:H7 str. TW14359 8219580 YP_003080788.1 CDS gldA NC_013008.1 5003987 5005090 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(5003987..5005090) Escherichia coli O157:H7 str. TW14359 8219581 YP_003080789.1 CDS fsaB NC_013008.1 5005101 5005763 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(5005101..5005763) Escherichia coli O157:H7 str. TW14359 8219582 YP_003080790.1 CDS ptsA NC_013008.1 5005775 5008276 R fused PTS enzymes: Hpr component, enzyme I component, enzyme IIA component complement(5005775..5008276) Escherichia coli O157:H7 str. TW14359 8219583 YP_003080791.1 CDS ECSP_5018 NC_013008.1 5008585 5009664 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 5008585..5009664 Escherichia coli O157:H7 str. TW14359 8219584 YP_003080792.1 CDS frwB NC_013008.1 5009679 5009999 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 5009679..5009999 Escherichia coli O157:H7 str. TW14359 8219585 YP_003080793.1 CDS pflD NC_013008.1 5010050 5012347 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 5010050..5012347 Escherichia coli O157:H7 str. TW14359 8219586 YP_003080794.1 CDS pflC NC_013008.1 5012313 5013191 D pyruvate formate lyase II activase 5012313..5013191 Escherichia coli O157:H7 str. TW14359 8219587 YP_003080795.1 CDS frwD NC_013008.1 5013193 5013534 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 5013193..5013534 Escherichia coli O157:H7 str. TW14359 8219588 YP_003080796.1 CDS yijO NC_013008.1 5013521 5014372 R DNA-binding transcriptional regulator complement(5013521..5014372) Escherichia coli O157:H7 str. TW14359 8219589 YP_003080797.1 CDS yijP NC_013008.1 5014587 5016320 R hypothetical protein complement(5014587..5016320) Escherichia coli O157:H7 str. TW14359 8219590 YP_003080798.1 CDS ppc NC_013008.1 5016503 5019154 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(5016503..5019154) Escherichia coli O157:H7 str. TW14359 8219591 YP_003080799.1 CDS argE NC_013008.1 5019506 5020657 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(5019506..5020657) Escherichia coli O157:H7 str. TW14359 8219592 YP_003080800.1 CDS argC NC_013008.1 5020811 5021815 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 5020811..5021815 Escherichia coli O157:H7 str. TW14359 8219593 YP_003080801.1 CDS argB NC_013008.1 5021823 5022599 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 5021823..5022599 Escherichia coli O157:H7 str. TW14359 8219594 YP_003080802.1 CDS argH NC_013008.1 5022660 5024033 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 5022660..5024033 Escherichia coli O157:H7 str. TW14359 8219595 YP_003080803.1 CDS oxyR NC_013008.1 5024300 5025217 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 5024300..5025217 Escherichia coli O157:H7 str. TW14359 8219596 YP_003080804.1 CDS sthA NC_013008.1 5025200 5026600 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(5025200..5026600) Escherichia coli O157:H7 str. TW14359 8219597 YP_003080805.1 CDS ECSP_5032 NC_013008.1 5026930 5028096 D hippuricase 5026930..5028096 Escherichia coli O157:H7 str. TW14359 8219598 YP_003080806.1 CDS ECSP_5033 NC_013008.1 5028139 5029455 D citrate permease 5028139..5029455 Escherichia coli O157:H7 str. TW14359 8219599 YP_003080807.1 CDS fabR NC_013008.1 5029562 5030209 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 5029562..5030209 Escherichia coli O157:H7 str. TW14359 8219600 YP_003080808.1 CDS yijD NC_013008.1 5030209 5030568 D hypothetical protein 5030209..5030568 Escherichia coli O157:H7 str. TW14359 8219601 YP_003080809.1 CDS trmA NC_013008.1 5030608 5031708 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(5030608..5031708) Escherichia coli O157:H7 str. TW14359 8219602 YP_003080810.1 CDS btuB NC_013008.1 5032077 5033921 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 5032077..5033921 Escherichia coli O157:H7 str. TW14359 8219603 YP_003080811.1 CDS murI NC_013008.1 5033866 5034723 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 5033866..5034723 Escherichia coli O157:H7 str. TW14359 8219604 YP_003080812.1 CDS murB NC_013008.1 5040247 5041275 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 5040247..5041275 Escherichia coli O157:H7 str. TW14359 8219609 YP_003080813.1 CDS birA NC_013008.1 5041272 5042237 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 5041272..5042237 Escherichia coli O157:H7 str. TW14359 8219610 YP_003080814.1 CDS coaA NC_013008.1 5042266 5043192 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(5042266..5043192) Escherichia coli O157:H7 str. TW14359 8219611 YP_003080815.1 CDS tufB NC_013008.1 5044134 5045318 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 5044134..5045318 Escherichia coli O157:H7 str. TW14359 8219616 YP_003080816.1 CDS secE NC_013008.1 5045548 5045931 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 5045548..5045931 Escherichia coli O157:H7 str. TW14359 8219617 YP_003080817.1 CDS nusG NC_013008.1 5045933 5046478 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 5045933..5046478 Escherichia coli O157:H7 str. TW14359 8219618 YP_003080818.1 CDS rplK NC_013008.1 5046637 5047065 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 5046637..5047065 Escherichia coli O157:H7 str. TW14359 8219619 YP_003080819.1 CDS rplA NC_013008.1 5047069 5047773 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 5047069..5047773 Escherichia coli O157:H7 str. TW14359 8219620 YP_003080820.1 CDS rplJ NC_013008.1 5048065 5048562 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 5048065..5048562 Escherichia coli O157:H7 str. TW14359 8219621 YP_003080821.1 CDS rplL NC_013008.1 5048629 5048994 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 5048629..5048994 Escherichia coli O157:H7 str. TW14359 8219622 YP_003080822.1 CDS rpoB NC_013008.1 5049314 5053342 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 5049314..5053342 Escherichia coli O157:H7 str. TW14359 8219623 YP_003080823.1 CDS rpoC NC_013008.1 5053419 5057642 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 5053419..5057642 Escherichia coli O157:H7 str. TW14359 8219624 YP_003080824.1 CDS htrC NC_013008.1 5057855 5058298 D heat shock protein 5057855..5058298 Escherichia coli O157:H7 str. TW14359 8219625 YP_003080825.1 CDS thiH NC_013008.1 5058733 5059866 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(5058733..5059866) Escherichia coli O157:H7 str. TW14359 8219626 YP_003080826.1 CDS thiG NC_013008.1 5059863 5060633 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(5059863..5060633) Escherichia coli O157:H7 str. TW14359 8219627 YP_003080827.1 CDS thiF NC_013008.1 5060819 5061574 R thiamin (thiazole moiety) biosynthesis protein complement(5060819..5061574) Escherichia coli O157:H7 str. TW14359 8219628 YP_003080828.1 CDS thiE NC_013008.1 5061567 5062202 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(5061567..5062202) Escherichia coli O157:H7 str. TW14359 8219629 YP_003080829.1 CDS thiC NC_013008.1 5062202 5064097 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(5062202..5064097) Escherichia coli O157:H7 str. TW14359 8219630 YP_003080830.1 CDS rsd NC_013008.1 5064330 5064806 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(5064330..5064806) Escherichia coli O157:H7 str. TW14359 8219631 YP_003080831.1 CDS nudC NC_013008.1 5064901 5065674 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 5064901..5065674 Escherichia coli O157:H7 str. TW14359 8219632 YP_003080832.1 CDS hemE NC_013008.1 5065714 5066778 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 5065714..5066778 Escherichia coli O157:H7 str. TW14359 8219633 YP_003080833.1 CDS nfi NC_013008.1 5066788 5067459 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 5066788..5067459 Escherichia coli O157:H7 str. TW14359 8219634 YP_003080834.1 CDS yjaG NC_013008.1 5067502 5068092 D hypothetical protein 5067502..5068092 Escherichia coli O157:H7 str. TW14359 8219635 YP_003080835.1 CDS hupA NC_013008.1 5068279 5068551 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 5068279..5068551 Escherichia coli O157:H7 str. TW14359 8219636 YP_003080836.1 CDS yjaH NC_013008.1 5068564 5069259 D hypothetical protein 5068564..5069259 Escherichia coli O157:H7 str. TW14359 8219637 YP_003080837.1 CDS zraP NC_013008.1 5069261 5069686 R zinc resistance protein complement(5069261..5069686) Escherichia coli O157:H7 str. TW14359 8219638 YP_003080838.1 CDS zraS NC_013008.1 5069924 5071300 D sensor protein ZraS 5069924..5071300 Escherichia coli O157:H7 str. TW14359 8219639 YP_003080839.1 CDS zraR NC_013008.1 5071297 5072622 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 5071297..5072622 Escherichia coli O157:H7 str. TW14359 8219640 YP_003080840.1 CDS purD NC_013008.1 5072619 5073908 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(5072619..5073908) Escherichia coli O157:H7 str. TW14359 8219641 YP_003080841.1 CDS purH NC_013008.1 5073920 5075509 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(5073920..5075509) Escherichia coli O157:H7 str. TW14359 8219642 YP_003080842.1 CDS yjaB NC_013008.1 5081253 5081696 R hypothetical protein complement(5081253..5081696) Escherichia coli O157:H7 str. TW14359 8219647 YP_003080843.1 CDS metA NC_013008.1 5081853 5082782 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 5081853..5082782 Escherichia coli O157:H7 str. TW14359 8219648 YP_003080844.1 CDS aceB NC_013008.1 5083051 5084652 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 5083051..5084652 Escherichia coli O157:H7 str. TW14359 8219649 YP_003080845.1 CDS aceA NC_013008.1 5084682 5085986 D isocitrate lyase 5084682..5085986 Escherichia coli O157:H7 str. TW14359 8219650 YP_003080846.1 CDS aceK NC_013008.1 5086170 5087906 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 5086170..5087906 Escherichia coli O157:H7 str. TW14359 8219651 YP_003080847.1 CDS espL4 NC_013008.1 5087875 5090061 R non-LEE-encoded type III effector complement(5087875..5090061) Escherichia coli O157:H7 str. TW14359 8219652 YP_003080848.1 CDS iclR NC_013008.1 5090378 5091202 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR complement(5090378..5091202) Escherichia coli O157:H7 str. TW14359 8219653 YP_003080849.1 CDS metH NC_013008.1 5091402 5095085 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 5091402..5095085 Escherichia coli O157:H7 str. TW14359 8219654 YP_003080850.1 CDS yjbB NC_013008.1 5095305 5096936 D transporter 5095305..5096936 Escherichia coli O157:H7 str. TW14359 8219655 YP_003080851.1 CDS pepE NC_013008.1 5097027 5097716 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(5097027..5097716) Escherichia coli O157:H7 str. TW14359 8219656 YP_003080852.1 CDS ECSP_5091 NC_013008.1 5098099 5099328 R L-sorbose-1-P-reductase complement(5098099..5099328) Escherichia coli O157:H7 str. TW14359 8219657 YP_003080853.1 CDS ECSP_5092 NC_013008.1 5099380 5100204 R sorbose PTS component complement(5099380..5100204) Escherichia coli O157:H7 str. TW14359 8219658 YP_003080854.1 CDS ECSP_5093 NC_013008.1 5100215 5101012 R sorbose PTS component complement(5100215..5101012) Escherichia coli O157:H7 str. TW14359 8219659 YP_003080855.1 CDS ECSP_5094 NC_013008.1 5101078 5101572 R sorbose PTS component complement(5101078..5101572) Escherichia coli O157:H7 str. TW14359 8219660 YP_003080856.1 CDS ECSP_5095 NC_013008.1 5101572 5101979 R sorbose PTS component complement(5101572..5101979) Escherichia coli O157:H7 str. TW14359 8219661 YP_003080857.1 CDS ECSP_5096 NC_013008.1 5101989 5102795 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(5101989..5102795) Escherichia coli O157:H7 str. TW14359 8219662 YP_003080858.1 CDS ECSP_5097 NC_013008.1 5102865 5103812 R transcriptional regulator of sorbose uptake and utilization genes complement(5102865..5103812) Escherichia coli O157:H7 str. TW14359 8219663 YP_003080859.1 CDS rluF NC_013008.1 5104160 5105032 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 5104160..5105032 Escherichia coli O157:H7 str. TW14359 8219664 YP_003080860.1 CDS yjbD NC_013008.1 5105033 5105305 R hypothetical protein complement(5105033..5105305) Escherichia coli O157:H7 str. TW14359 8219665 YP_003080861.1 CDS lysC NC_013008.1 5105558 5106907 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase complement(5105558..5106907) Escherichia coli O157:H7 str. TW14359 8219666 YP_003080862.1 CDS pgi NC_013008.1 5107432 5109081 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 5107432..5109081 Escherichia coli O157:H7 str. TW14359 8219667 YP_003080863.1 CDS yjbE NC_013008.1 5109594 5109836 D hypothetical protein 5109594..5109836 Escherichia coli O157:H7 str. TW14359 8219668 YP_003080864.1 CDS yjbF NC_013008.1 5109950 5110588 D lipoprotein 5109950..5110588 Escherichia coli O157:H7 str. TW14359 8219669 YP_003080865.1 CDS yjbG NC_013008.1 5110585 5111322 D hypothetical protein 5110585..5111322 Escherichia coli O157:H7 str. TW14359 8219670 YP_003080866.1 CDS yjbH NC_013008.1 5111322 5113418 D porin 5111322..5113418 Escherichia coli O157:H7 str. TW14359 8219671 YP_003080867.1 CDS ECSP_5106 NC_013008.1 5113465 5113743 R hypothetical protein complement(5113465..5113743) Escherichia coli O157:H7 str. TW14359 8219672 YP_003080868.1 CDS ECSP_5107 NC_013008.1 5113744 5113887 D hypothetical protein 5113744..5113887 Escherichia coli O157:H7 str. TW14359 8219673 YP_003080869.1 CDS psiE NC_013008.1 5114013 5114423 D phosphate-starvation-inducible protein PsiE 5114013..5114423 Escherichia coli O157:H7 str. TW14359 8219674 YP_003080870.1 CDS xylE NC_013008.1 5114467 5115942 R xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE complement(5114467..5115942) Escherichia coli O157:H7 str. TW14359 8219675 YP_003080871.1 CDS malG NC_013008.1 5116314 5117204 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(5116314..5117204) Escherichia coli O157:H7 str. TW14359 8219676 YP_003080872.1 CDS malF NC_013008.1 5117219 5118763 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(5117219..5118763) Escherichia coli O157:H7 str. TW14359 8219677 YP_003080873.1 CDS malE NC_013008.1 5118917 5120107 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(5118917..5120107) Escherichia coli O157:H7 str. TW14359 8219678 YP_003080874.1 CDS malK NC_013008.1 5120472 5121587 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 5120472..5121587 Escherichia coli O157:H7 str. TW14359 8219679 YP_003080875.1 CDS lamB NC_013008.1 5121659 5122999 D porin involved in the transport of maltose and maltodextrins; maltoporin 5121659..5122999 Escherichia coli O157:H7 str. TW14359 8219680 YP_003080876.1 CDS malM NC_013008.1 5123150 5124070 D maltose regulon periplasmic protein 5123150..5124070 Escherichia coli O157:H7 str. TW14359 8219681 YP_003080877.1 CDS espX4 NC_013008.1 5124299 5125879 D in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 5124299..5125879 Escherichia coli O157:H7 str. TW14359 8219682 YP_003080878.1 CDS ubiC NC_013008.1 5126102 5126599 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 5126102..5126599 Escherichia coli O157:H7 str. TW14359 8219683 YP_003080879.1 CDS ubiA NC_013008.1 5126612 5127484 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 5126612..5127484 Escherichia coli O157:H7 str. TW14359 8219684 YP_003080880.1 CDS plsB NC_013008.1 5127639 5130062 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(5127639..5130062) Escherichia coli O157:H7 str. TW14359 8219685 YP_003080881.1 CDS dgkA NC_013008.1 5130233 5130601 D diacylglycerol kinase 5130233..5130601 Escherichia coli O157:H7 str. TW14359 8219686 YP_003080882.1 CDS lexA NC_013008.1 5130711 5131319 D Represses a number of genes involved in the response to DNA damage; LexA repressor 5130711..5131319 Escherichia coli O157:H7 str. TW14359 8219687 YP_003080883.1 CDS dinF NC_013008.1 5131338 5132717 D DNA-damage-inducible SOS response protein 5131338..5132717 Escherichia coli O157:H7 str. TW14359 8219688 YP_003080884.1 CDS yjbJ NC_013008.1 5132833 5133042 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 5132833..5133042 Escherichia coli O157:H7 str. TW14359 8219689 YP_003080885.1 CDS zur NC_013008.1 5133084 5133599 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(5133084..5133599) Escherichia coli O157:H7 str. TW14359 8219690 YP_003080886.1 CDS yjbM NC_013008.1 5133911 5134867 D hypothetical protein 5133911..5134867 Escherichia coli O157:H7 str. TW14359 8219691 YP_003080887.1 CDS ECSP_5126 NC_013008.1 5135229 5135351 D hypothetical protein 5135229..5135351 Escherichia coli O157:H7 str. TW14359 8219692 YP_003080888.1 CDS ECSP_5127 NC_013008.1 5135480 5136013 D hypothetical protein 5135480..5136013 Escherichia coli O157:H7 str. TW14359 8219693 YP_003080889.1 CDS ECSP_5128 NC_013008.1 5136210 5136383 D hypothetical protein 5136210..5136383 Escherichia coli O157:H7 str. TW14359 8219694 YP_003080890.1 CDS ECSP_5129 NC_013008.1 5136431 5136724 R hypothetical protein complement(5136431..5136724) Escherichia coli O157:H7 str. TW14359 8219695 YP_003080891.1 CDS ECSP_5130 NC_013008.1 5136749 5137087 R endodeoxyribonuclease complement(5136749..5137087) Escherichia coli O157:H7 str. TW14359 8219696 YP_003080892.1 CDS ECSP_5131 NC_013008.1 5137057 5137254 R hypothetical protein complement(5137057..5137254) Escherichia coli O157:H7 str. TW14359 8219697 YP_003080893.1 CDS ECSP_5133 NC_013008.1 5137871 5138200 R hypothetical protein complement(5137871..5138200) Escherichia coli O157:H7 str. TW14359 8219699 YP_003080894.1 CDS ECSP_5134 NC_013008.1 5138212 5138748 R hypothetical protein complement(5138212..5138748) Escherichia coli O157:H7 str. TW14359 8219700 YP_003080895.1 CDS ECSP_5135 NC_013008.1 5138876 5139262 R hypothetical protein complement(5138876..5139262) Escherichia coli O157:H7 str. TW14359 8219701 YP_003080896.1 CDS ECSP_5136 NC_013008.1 5139349 5140002 D hypothetical protein 5139349..5140002 Escherichia coli O157:H7 str. TW14359 8219702 YP_003080897.1 CDS ECSP_5137 NC_013008.1 5140070 5140669 D Ail/Lom family protein 5140070..5140669 Escherichia coli O157:H7 str. TW14359 8219703 YP_003080898.1 CDS ECSP_5138 NC_013008.1 5140734 5142047 D tail fiber protein 5140734..5142047 Escherichia coli O157:H7 str. TW14359 8219704 YP_003080899.1 CDS ECSP_5139 NC_013008.1 5142049 5142318 D hypothetical protein 5142049..5142318 Escherichia coli O157:H7 str. TW14359 8219705 YP_003080900.1 CDS ECSP_5140 NC_013008.1 5142430 5143002 D hypothetical protein 5142430..5143002 Escherichia coli O157:H7 str. TW14359 8219706 YP_003080901.1 CDS ECSP_5141 NC_013008.1 5143138 5143704 D hypothetical protein 5143138..5143704 Escherichia coli O157:H7 str. TW14359 8219707 YP_003080902.1 CDS ECSP_5142 NC_013008.1 5143786 5144427 D hypothetical protein 5143786..5144427 Escherichia coli O157:H7 str. TW14359 8219708 YP_003080903.1 CDS ECSP_5143 NC_013008.1 5144588 5144836 R hypothetical protein complement(5144588..5144836) Escherichia coli O157:H7 str. TW14359 8219709 YP_003080904.1 CDS ECSP_5144 NC_013008.1 5144898 5145995 R phage integrase family protein complement(5144898..5145995) Escherichia coli O157:H7 str. TW14359 8219710 YP_003080905.1 CDS dusA NC_013008.1 5146129 5147121 D tRNA-dihydrouridine synthase A 5146129..5147121 Escherichia coli O157:H7 str. TW14359 8219711 YP_003080906.1 CDS pspG NC_013008.1 5147255 5147497 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 5147255..5147497 Escherichia coli O157:H7 str. TW14359 8219712 YP_003080907.1 CDS qor NC_013008.1 5147663 5148646 R quinone oxidoreductase, NADPH-dependent complement(5147663..5148646) Escherichia coli O157:H7 str. TW14359 8219713 YP_003080908.1 CDS dnaB NC_013008.1 5148729 5150144 D unwinds double stranded DNA; replicative DNA helicase 5148729..5150144 Escherichia coli O157:H7 str. TW14359 8219714 YP_003080909.1 CDS alr NC_013008.1 5150197 5151276 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 5150197..5151276 Escherichia coli O157:H7 str. TW14359 8219715 YP_003080910.1 CDS tyrB NC_013008.1 5151529 5152722 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 5151529..5152722 Escherichia coli O157:H7 str. TW14359 8219716 YP_003080911.1 CDS ECSP_5151 NC_013008.1 5153061 5153420 R hypothetical protein complement(5153061..5153420) Escherichia coli O157:H7 str. TW14359 8219717 YP_003080912.1 CDS aphA NC_013008.1 5153821 5154534 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 5153821..5154534 Escherichia coli O157:H7 str. TW14359 8219718 YP_003080913.1 CDS yjbQ NC_013008.1 5154645 5155061 D hypothetical protein 5154645..5155061 Escherichia coli O157:H7 str. TW14359 8219719 YP_003080914.1 CDS yjbR NC_013008.1 5155065 5155421 D hypothetical protein 5155065..5155421 Escherichia coli O157:H7 str. TW14359 8219720 YP_003080915.1 CDS uvrA NC_013008.1 5155456 5158278 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(5155456..5158278) Escherichia coli O157:H7 str. TW14359 8219721 YP_003080916.1 CDS ECSP_5156 NC_013008.1 5158533 5159069 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 5158533..5159069 Escherichia coli O157:H7 str. TW14359 8219722 YP_003080917.1 CDS yjcB NC_013008.1 5159168 5159449 R inner membrane protein complement(5159168..5159449) Escherichia coli O157:H7 str. TW14359 8219723 YP_003080918.1 CDS yjcC NC_013008.1 5159878 5161464 D signal transduction protein 5159878..5161464 Escherichia coli O157:H7 str. TW14359 8219724 YP_003080919.1 CDS soxS NC_013008.1 5161467 5161790 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(5161467..5161790) Escherichia coli O157:H7 str. TW14359 8219725 YP_003080920.1 CDS soxR NC_013008.1 5161876 5162340 D DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 5161876..5162340 Escherichia coli O157:H7 str. TW14359 8219726 YP_003080921.1 CDS yjcD NC_013008.1 5162886 5164235 D permease 5162886..5164235 Escherichia coli O157:H7 str. TW14359 8219727 YP_003080922.1 CDS yjcE NC_013008.1 5164386 5166035 D cation/proton antiporter 5164386..5166035 Escherichia coli O157:H7 str. TW14359 8219728 YP_003080923.1 CDS espX5 NC_013008.1 5166189 5167481 R non-LEE-encoded type III effector complement(5166189..5167481) Escherichia coli O157:H7 str. TW14359 8219729 YP_003080924.1 CDS actP NC_013008.1 5167662 5169311 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(5167662..5169311) Escherichia coli O157:H7 str. TW14359 8219730 YP_003080925.1 CDS yjcH NC_013008.1 5169308 5169622 R acetate transport inner membrane protein complement(5169308..5169622) Escherichia coli O157:H7 str. TW14359 8219731 YP_003080926.1 CDS acs NC_013008.1 5169823 5171781 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(5169823..5171781) Escherichia coli O157:H7 str. TW14359 8219732 YP_003080927.1 CDS nrfA NC_013008.1 5172174 5173610 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 5172174..5173610 Escherichia coli O157:H7 str. TW14359 8219733 YP_003080928.1 CDS nrfB NC_013008.1 5173655 5174221 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 5173655..5174221 Escherichia coli O157:H7 str. TW14359 8219734 YP_003080929.1 CDS nrfC NC_013008.1 5174218 5174889 D formate-dependent nitrite reductase, 4Fe4S subunit 5174218..5174889 Escherichia coli O157:H7 str. TW14359 8219735 YP_003080930.1 CDS nrfD NC_013008.1 5174886 5175842 D formate-dependent nitrite reductase, membrane subunit 5174886..5175842 Escherichia coli O157:H7 str. TW14359 8219736 YP_003080931.1 CDS nrfE NC_013008.1 5175922 5177580 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 5175922..5177580 Escherichia coli O157:H7 str. TW14359 8219737 YP_003080932.1 CDS nrfF NC_013008.1 5177573 5177956 D formate-dependent nitrite reductase complex subunit NrfF 5177573..5177956 Escherichia coli O157:H7 str. TW14359 8219738 YP_003080933.1 CDS nrfG NC_013008.1 5177953 5178549 D formate-dependent nitrite reductase complex subunit NrfG 5177953..5178549 Escherichia coli O157:H7 str. TW14359 8219739 YP_003080934.1 CDS gltP NC_013008.1 5178891 5180204 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 5178891..5180204 Escherichia coli O157:H7 str. TW14359 8219740 YP_003080935.1 CDS yjcO NC_013008.1 5180382 5181071 R hypothetical protein complement(5180382..5181071) Escherichia coli O157:H7 str. TW14359 8219741 YP_003080936.1 CDS fdhF NC_013008.1 5181165 5182844 R formate dehydrogenase-H, selenopolypeptide subunit complement(5181165..5182844) Escherichia coli O157:H7 str. TW14359 8219742 YP_003080937.1 CDS yjcP NC_013008.1 5183510 5184976 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(5183510..5184976) Escherichia coli O157:H7 str. TW14359 8219743 YP_003080938.1 CDS yjcQ NC_013008.1 5184973 5187024 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(5184973..5187024) Escherichia coli O157:H7 str. TW14359 8219744 YP_003080939.1 CDS yjcR NC_013008.1 5187024 5188055 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(5187024..5188055) Escherichia coli O157:H7 str. TW14359 8219745 YP_003080940.1 CDS ECSP_5180 NC_013008.1 5188074 5188349 R hypothetical protein complement(5188074..5188349) Escherichia coli O157:H7 str. TW14359 8219746 YP_003080941.1 CDS ECSP_5181 NC_013008.1 5188466 5188585 R hypothetical protein complement(5188466..5188585) Escherichia coli O157:H7 str. TW14359 8219747 YP_003080942.1 CDS yjcS NC_013008.1 5188558 5190543 R alkyl sulfatase complement(5188558..5190543) Escherichia coli O157:H7 str. TW14359 8219748 YP_003080943.1 CDS ECSP_5183 NC_013008.1 5190834 5191541 D transcriptional regulator 5190834..5191541 Escherichia coli O157:H7 str. TW14359 8219749 YP_003080944.1 CDS ECSP_5184 NC_013008.1 5191538 5192539 R kinase complement(5191538..5192539) Escherichia coli O157:H7 str. TW14359 8219750 YP_003080945.1 CDS ECSP_5185 NC_013008.1 5192536 5193396 R hypothetical protein complement(5192536..5193396) Escherichia coli O157:H7 str. TW14359 8219751 YP_003080946.1 CDS ECSP_5186 NC_013008.1 5193411 5194094 R hypothetical protein complement(5193411..5194094) Escherichia coli O157:H7 str. TW14359 8219752 YP_003080947.1 CDS ECSP_5187 NC_013008.1 5194149 5195090 R periplasmic ribose-binding protein of ABC transport system complement(5194149..5195090) Escherichia coli O157:H7 str. TW14359 8219753 YP_003080948.1 CDS ECSP_5188 NC_013008.1 5195109 5196083 R permease of ribose ABC transport system complement(5195109..5196083) Escherichia coli O157:H7 str. TW14359 8219754 YP_003080949.1 CDS ECSP_5189 NC_013008.1 5196080 5197600 R ATP-binding protein of ribose ABC transport system complement(5196080..5197600) Escherichia coli O157:H7 str. TW14359 8219755 YP_003080950.1 CDS ECSP_5190 NC_013008.1 5197714 5199984 D histidine kinase 5197714..5199984 Escherichia coli O157:H7 str. TW14359 8219756 YP_003080951.1 CDS yjdP NC_013008.1 5200053 5200382 D hypothetical protein 5200053..5200382 Escherichia coli O157:H7 str. TW14359 8219757 YP_003080952.1 CDS phnP NC_013008.1 5200459 5201217 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(5200459..5201217) Escherichia coli O157:H7 str. TW14359 8219758 YP_003080953.1 CDS ECSP_5193 NC_013008.1 5201219 5201644 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(5201219..5201644) Escherichia coli O157:H7 str. TW14359 8219759 YP_003080954.1 CDS phnN NC_013008.1 5201641 5202198 R ribose 1,5-bisphosphokinase complement(5201641..5202198) Escherichia coli O157:H7 str. TW14359 8219760 YP_003080955.1 CDS phnM NC_013008.1 5202198 5203334 R carbon-phosphorus lyase complex subunit complement(5202198..5203334) Escherichia coli O157:H7 str. TW14359 8219761 YP_003080956.1 CDS phnL NC_013008.1 5203331 5204011 R carbon-phosphorus lyase complex subunit complement(5203331..5204011) Escherichia coli O157:H7 str. TW14359 8219762 YP_003080957.1 CDS phnK NC_013008.1 5204122 5204880 R phosphonate C-P lyase system protein PhnK complement(5204122..5204880) Escherichia coli O157:H7 str. TW14359 8219763 YP_003080958.1 CDS phnJ NC_013008.1 5204877 5205722 R carbon-phosphorus lyase complex subunit complement(5204877..5205722) Escherichia coli O157:H7 str. TW14359 8219764 YP_003080959.1 CDS phnI NC_013008.1 5205715 5206779 R carbon-phosphorus lyase complex subunit complement(5205715..5206779) Escherichia coli O157:H7 str. TW14359 8219765 YP_003080960.1 CDS phnH NC_013008.1 5206779 5207363 R carbon-phosphorus lyase complex subunit complement(5206779..5207363) Escherichia coli O157:H7 str. TW14359 8219766 YP_003080961.1 CDS phnG NC_013008.1 5207360 5207812 R carbon-phosphorus lyase complex subunit complement(5207360..5207812) Escherichia coli O157:H7 str. TW14359 8219767 YP_003080962.1 CDS phnF NC_013008.1 5207813 5208538 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(5207813..5208538) Escherichia coli O157:H7 str. TW14359 8219768 YP_003080963.1 CDS phnE NC_013008.1 5208559 5209389 R membrane channel protein component of Pn transporter complement(5208559..5209389) Escherichia coli O157:H7 str. TW14359 8219769 YP_003080964.1 CDS phnD NC_013008.1 5209444 5210460 R phosphonate ABC transporter substrate-binding protein complement(5209444..5210460) Escherichia coli O157:H7 str. TW14359 8219770 YP_003080965.1 CDS phnC NC_013008.1 5210485 5211273 R phosphonate/organophosphate ester transporter subunit complement(5210485..5211273) Escherichia coli O157:H7 str. TW14359 8219771 YP_003080966.1 CDS phnB NC_013008.1 5211406 5211849 R hypothetical protein complement(5211406..5211849) Escherichia coli O157:H7 str. TW14359 8219772 YP_003080967.1 CDS phnA NC_013008.1 5212108 5212443 R hypothetical protein complement(5212108..5212443) Escherichia coli O157:H7 str. TW14359 8219773 YP_003080968.1 CDS yjdA NC_013008.1 5212845 5215073 D hypothetical protein 5212845..5215073 Escherichia coli O157:H7 str. TW14359 8219774 YP_003080969.1 CDS yjcZ NC_013008.1 5215070 5215948 D hypothetical protein 5215070..5215948 Escherichia coli O157:H7 str. TW14359 8219775 YP_003080970.1 CDS proP NC_013008.1 5216212 5217714 D proline/glycine betaine transporter 5216212..5217714 Escherichia coli O157:H7 str. TW14359 8219776 YP_003080971.1 CDS basS NC_013008.1 5217891 5218982 R sensor protein BasS/PmrB complement(5217891..5218982) Escherichia coli O157:H7 str. TW14359 8219777 YP_003080972.1 CDS basR NC_013008.1 5218992 5219660 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(5218992..5219660) Escherichia coli O157:H7 str. TW14359 8219778 YP_003080973.1 CDS eptA NC_013008.1 5219657 5221300 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(5219657..5221300) Escherichia coli O157:H7 str. TW14359 8219779 YP_003080974.1 CDS adiC NC_013008.1 5221404 5222741 R arginine:agmatin antiporter complement(5221404..5222741) Escherichia coli O157:H7 str. TW14359 8219780 YP_003080975.1 CDS adiY NC_013008.1 5222878 5223639 R DNA-binding transcriptional activator complement(5222878..5223639) Escherichia coli O157:H7 str. TW14359 8219781 YP_003080976.1 CDS adiA NC_013008.1 5223964 5226234 R biodegradative arginine decarboxylase complement(5223964..5226234) Escherichia coli O157:H7 str. TW14359 8219782 YP_003080977.1 CDS melR NC_013008.1 5226430 5227338 R DNA-binding transcriptional regulator MelR complement(5226430..5227338) Escherichia coli O157:H7 str. TW14359 8219783 YP_003080978.1 CDS melA NC_013008.1 5227621 5228976 D alpha-galactosidase 5227621..5228976 Escherichia coli O157:H7 str. TW14359 8219784 YP_003080979.1 CDS melB NC_013008.1 5229091 5230500 D melibiose:sodium symporter 5229091..5230500 Escherichia coli O157:H7 str. TW14359 8219785 YP_003080980.1 CDS yjdF NC_013008.1 5230639 5231268 R hypothetical protein complement(5230639..5231268) Escherichia coli O157:H7 str. TW14359 8219786 YP_003080981.1 CDS fumB NC_013008.1 5231391 5233037 R anaerobic class I fumarate hydratase complement(5231391..5233037) Escherichia coli O157:H7 str. TW14359 8219787 YP_003080982.1 CDS dcuB NC_013008.1 5233115 5234455 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(5233115..5234455) Escherichia coli O157:H7 str. TW14359 8219788 YP_003080983.1 CDS dcuR NC_013008.1 5235026 5235745 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(5235026..5235745) Escherichia coli O157:H7 str. TW14359 8219789 YP_003080984.1 CDS dcuS NC_013008.1 5235742 5237373 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(5235742..5237373) Escherichia coli O157:H7 str. TW14359 8219790 YP_003080985.1 CDS yjdI NC_013008.1 5237554 5237784 D hypothetical protein 5237554..5237784 Escherichia coli O157:H7 str. TW14359 8219791 YP_003080986.1 CDS yjdJ NC_013008.1 5237796 5238068 D acyl-CoA N-acyltransferase domain-containing acyltransferase 5237796..5238068 Escherichia coli O157:H7 str. TW14359 8219792 YP_003080987.1 CDS yjdK NC_013008.1 5238295 5238591 D hypothetical protein 5238295..5238591 Escherichia coli O157:H7 str. TW14359 8219793 YP_003080988.1 CDS yjdO NC_013008.1 5238619 5238792 D hypothetical protein 5238619..5238792 Escherichia coli O157:H7 str. TW14359 8219794 YP_003080989.1 CDS lysU NC_013008.1 5238911 5240428 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(5238911..5240428) Escherichia coli O157:H7 str. TW14359 8219795 YP_003080990.1 CDS yjdL NC_013008.1 5240665 5242122 R transporter complement(5240665..5242122) Escherichia coli O157:H7 str. TW14359 8219796 YP_003080991.1 CDS cadA NC_013008.1 5242181 5244328 R lysine decarboxylase 1 complement(5242181..5244328) Escherichia coli O157:H7 str. TW14359 8219797 YP_003080992.1 CDS cadB NC_013008.1 5244408 5245742 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(5244408..5245742) Escherichia coli O157:H7 str. TW14359 8219798 YP_003080993.1 CDS cadC NC_013008.1 5246108 5247646 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(5246108..5247646) Escherichia coli O157:H7 str. TW14359 8219799 YP_003080994.1 CDS yjdC NC_013008.1 5248445 5249020 R transcriptional regulator complement(5248445..5249020) Escherichia coli O157:H7 str. TW14359 8219801 YP_003080995.1 CDS dipZ NC_013008.1 5249057 5250754 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(5249057..5250754) Escherichia coli O157:H7 str. TW14359 8219802 YP_003080996.1 CDS cutA NC_013008.1 5250730 5251068 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(5250730..5251068) Escherichia coli O157:H7 str. TW14359 8219803 YP_003080997.1 CDS dcuA NC_013008.1 5251184 5252485 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(5251184..5252485) Escherichia coli O157:H7 str. TW14359 8219804 YP_003080998.1 CDS aspA NC_013008.1 5252603 5254039 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(5252603..5254039) Escherichia coli O157:H7 str. TW14359 8219805 YP_003080999.1 CDS fxsA NC_013008.1 5254376 5254852 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 5254376..5254852 Escherichia coli O157:H7 str. TW14359 8219806 YP_003081000.1 CDS yjeH NC_013008.1 5254673 5256124 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(5254673..5256124) Escherichia coli O157:H7 str. TW14359 8219807 YP_003081001.1 CDS groES NC_013008.1 5256400 5256693 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 5256400..5256693 Escherichia coli O157:H7 str. TW14359 8219808 YP_003081002.1 CDS groEL NC_013008.1 5256737 5258383 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 5256737..5258383 Escherichia coli O157:H7 str. TW14359 8219809 YP_003081003.1 CDS yjeI NC_013008.1 5258521 5258874 D hypothetical protein 5258521..5258874 Escherichia coli O157:H7 str. TW14359 8219810 YP_003081004.1 CDS yjeJ NC_013008.1 5259067 5259936 R hypothetical protein complement(5259067..5259936) Escherichia coli O157:H7 str. TW14359 8219811 YP_003081005.1 CDS yjeK NC_013008.1 5260171 5261199 R lysine 2,3-aminomutase complement(5260171..5261199) Escherichia coli O157:H7 str. TW14359 8219812 YP_003081006.1 CDS efp NC_013008.1 5261241 5261807 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 5261241..5261807 Escherichia coli O157:H7 str. TW14359 8219813 YP_003081007.1 CDS ecnA NC_013008.1 5261859 5261984 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 5261859..5261984 Escherichia coli O157:H7 str. TW14359 8219814 YP_003081008.1 CDS ecnB NC_013008.1 5262095 5262241 D entericidin B membrane lipoprotein 5262095..5262241 Escherichia coli O157:H7 str. TW14359 8219815 YP_003081009.1 CDS sugE NC_013008.1 5262417 5262734 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 5262417..5262734 Escherichia coli O157:H7 str. TW14359 8219816 YP_003081010.1 CDS blc NC_013008.1 5262731 5263264 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(5262731..5263264) Escherichia coli O157:H7 str. TW14359 8219817 YP_003081011.1 CDS ampC NC_013008.1 5263352 5264485 R beta-lactamase complement(5263352..5264485) Escherichia coli O157:H7 str. TW14359 8219818 YP_003081012.1 CDS frdD NC_013008.1 5264548 5264907 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(5264548..5264907) Escherichia coli O157:H7 str. TW14359 8219819 YP_003081013.1 CDS frdC NC_013008.1 5264918 5265313 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(5264918..5265313) Escherichia coli O157:H7 str. TW14359 8219820 YP_003081014.1 CDS frdB NC_013008.1 5265324 5266058 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(5265324..5266058) Escherichia coli O157:H7 str. TW14359 8219821 YP_003081015.1 CDS frdA NC_013008.1 5266051 5267859 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(5266051..5267859) Escherichia coli O157:H7 str. TW14359 8219822 YP_003081016.1 CDS poxA NC_013008.1 5268184 5269161 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 5268184..5269161 Escherichia coli O157:H7 str. TW14359 8219823 YP_003081017.1 CDS yjeM NC_013008.1 5269380 5270882 D transporter 5269380..5270882 Escherichia coli O157:H7 str. TW14359 8219824 YP_003081018.1 CDS yjeP NC_013008.1 5271033 5274356 R hypothetical protein complement(5271033..5274356) Escherichia coli O157:H7 str. TW14359 8219825 YP_003081019.1 CDS psd NC_013008.1 5274378 5275346 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(5274378..5275346) Escherichia coli O157:H7 str. TW14359 8219826 YP_003081020.1 CDS rsgA NC_013008.1 5275443 5276495 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(5275443..5276495) Escherichia coli O157:H7 str. TW14359 8219827 YP_003081021.1 CDS orn NC_013008.1 5276590 5277135 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 5276590..5277135 Escherichia coli O157:H7 str. TW14359 8219828 YP_003081022.1 CDS yjeS NC_013008.1 5277914 5279053 R Fe-S electron transport protein complement(5277914..5279053) Escherichia coli O157:H7 str. TW14359 8219832 YP_003081023.1 CDS yjeF NC_013008.1 5279052 5280599 D hypothetical protein 5279052..5280599 Escherichia coli O157:H7 str. TW14359 8219833 YP_003081024.1 CDS yjeE NC_013008.1 5280571 5281032 D possibly involved in cell wall synthesis; ATPase 5280571..5281032 Escherichia coli O157:H7 str. TW14359 8219834 YP_003081025.1 CDS amiB NC_013008.1 5281051 5282388 D N-acetylmuramoyl-l-alanine amidase II 5281051..5282388 Escherichia coli O157:H7 str. TW14359 8219835 YP_003081026.1 CDS mutL NC_013008.1 5282398 5284245 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 5282398..5284245 Escherichia coli O157:H7 str. TW14359 8219836 YP_003081027.1 CDS miaA NC_013008.1 5284238 5285188 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 5284238..5285188 Escherichia coli O157:H7 str. TW14359 8219837 YP_003081028.1 CDS hfq NC_013008.1 5285274 5285582 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 5285274..5285582 Escherichia coli O157:H7 str. TW14359 8219838 YP_003081029.1 CDS hflX NC_013008.1 5285659 5286939 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 5285659..5286939 Escherichia coli O157:H7 str. TW14359 8219839 YP_003081030.1 CDS hflK NC_013008.1 5287025 5288284 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 5287025..5288284 Escherichia coli O157:H7 str. TW14359 8219840 YP_003081031.1 CDS hflC NC_013008.1 5288287 5289291 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 5288287..5289291 Escherichia coli O157:H7 str. TW14359 8219841 YP_003081032.1 CDS yjeT NC_013008.1 5289373 5289570 D hypothetical protein 5289373..5289570 Escherichia coli O157:H7 str. TW14359 8219842 YP_003081033.1 CDS purA NC_013008.1 5289674 5290972 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5289674..5290972 Escherichia coli O157:H7 str. TW14359 8219843 YP_003081034.1 CDS nsrR NC_013008.1 5291177 5291602 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 5291177..5291602 Escherichia coli O157:H7 str. TW14359 8219844 YP_003081035.1 CDS rnr NC_013008.1 5291641 5294082 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 5291641..5294082 Escherichia coli O157:H7 str. TW14359 8219845 YP_003081036.1 CDS rlmB NC_013008.1 5294263 5294994 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 5294263..5294994 Escherichia coli O157:H7 str. TW14359 8219846 YP_003081037.1 CDS yjfI NC_013008.1 5295121 5295522 D hypothetical protein 5295121..5295522 Escherichia coli O157:H7 str. TW14359 8219847 YP_003081038.1 CDS yjfJ NC_013008.1 5295541 5296239 D transcriptional regulator effector protein 5295541..5296239 Escherichia coli O157:H7 str. TW14359 8219848 YP_003081039.1 CDS yjfK NC_013008.1 5296290 5296949 D hypothetical protein 5296290..5296949 Escherichia coli O157:H7 str. TW14359 8219849 YP_003081040.1 CDS yjfL NC_013008.1 5296967 5297365 D hypothetical protein 5296967..5297365 Escherichia coli O157:H7 str. TW14359 8219850 YP_003081041.1 CDS yjfM NC_013008.1 5297375 5298013 D hypothetical protein 5297375..5298013 Escherichia coli O157:H7 str. TW14359 8219851 YP_003081042.1 CDS yjfC NC_013008.1 5298016 5299179 D synthetase/amidase 5298016..5299179 Escherichia coli O157:H7 str. TW14359 8219852 YP_003081043.1 CDS aidB NC_013008.1 5299263 5300888 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 5299263..5300888 Escherichia coli O157:H7 str. TW14359 8219853 YP_003081044.1 CDS yjfN NC_013008.1 5301005 5301280 R hypothetical protein complement(5301005..5301280) Escherichia coli O157:H7 str. TW14359 8219854 YP_003081045.1 CDS yjfO NC_013008.1 5301429 5301758 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(5301429..5301758) Escherichia coli O157:H7 str. TW14359 8219855 YP_003081046.1 CDS yjfP NC_013008.1 5301940 5302689 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 5301940..5302689 Escherichia coli O157:H7 str. TW14359 8219856 YP_003081047.1 CDS ulaR NC_013008.1 5302686 5303441 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(5302686..5303441) Escherichia coli O157:H7 str. TW14359 8219857 YP_003081048.1 CDS ulaG NC_013008.1 5303549 5304613 R L-ascorbate 6-phosphate lactonase complement(5303549..5304613) Escherichia coli O157:H7 str. TW14359 8219858 YP_003081049.1 CDS ulaA NC_013008.1 5304968 5306365 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 5304968..5306365 Escherichia coli O157:H7 str. TW14359 8219859 YP_003081050.1 CDS ulaB NC_013008.1 5306381 5306686 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 5306381..5306686 Escherichia coli O157:H7 str. TW14359 8219860 YP_003081051.1 CDS ulaC NC_013008.1 5306696 5307160 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 5306696..5307160 Escherichia coli O157:H7 str. TW14359 8219861 YP_003081052.1 CDS ulaD NC_013008.1 5307174 5307824 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 5307174..5307824 Escherichia coli O157:H7 str. TW14359 8219862 YP_003081053.1 CDS ulaE NC_013008.1 5307834 5308688 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 5307834..5308688 Escherichia coli O157:H7 str. TW14359 8219863 YP_003081054.1 CDS sgaE NC_013008.1 5308688 5309374 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 5308688..5309374 Escherichia coli O157:H7 str. TW14359 8219864 YP_003081055.1 CDS yjfY NC_013008.1 5309503 5309778 R hypothetical protein complement(5309503..5309778) Escherichia coli O157:H7 str. TW14359 8219865 YP_003081056.1 CDS rpsF NC_013008.1 5310105 5310500 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 5310105..5310500 Escherichia coli O157:H7 str. TW14359 8219866 YP_003081057.1 CDS priB NC_013008.1 5310507 5310821 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 5310507..5310821 Escherichia coli O157:H7 str. TW14359 8219867 YP_003081058.1 CDS rpsR NC_013008.1 5310826 5311053 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5310826..5311053 Escherichia coli O157:H7 str. TW14359 8219868 YP_003081059.1 CDS rplI NC_013008.1 5311095 5311544 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 5311095..5311544 Escherichia coli O157:H7 str. TW14359 8219869 YP_003081060.1 CDS yjfZ NC_013008.1 5311615 5312409 R hypothetical protein complement(5311615..5312409) Escherichia coli O157:H7 str. TW14359 8219870 YP_003081061.1 CDS ECSP_5305 NC_013008.1 5312849 5313031 R hypothetical protein complement(5312849..5313031) Escherichia coli O157:H7 str. TW14359 8219871 YP_003081062.1 CDS ECSP_5306 NC_013008.1 5313032 5313463 R transposase complement(5313032..5313463) Escherichia coli O157:H7 str. TW14359 8219872 YP_003081063.1 CDS ECSP_5307 NC_013008.1 5313471 5314679 D virulence protein 5313471..5314679 Escherichia coli O157:H7 str. TW14359 8219873 YP_003081064.1 CDS ytfB NC_013008.1 5314814 5315452 R cell envelope opacity-associated protein complement(5314814..5315452) Escherichia coli O157:H7 str. TW14359 8219874 YP_003081065.1 CDS fklB NC_013008.1 5315670 5316290 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 5315670..5316290 Escherichia coli O157:H7 str. TW14359 8219875 YP_003081066.1 CDS cycA NC_013008.1 5316599 5318011 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 5316599..5318011 Escherichia coli O157:H7 str. TW14359 8219876 YP_003081067.1 CDS ytfE NC_013008.1 5318056 5318718 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(5318056..5318718) Escherichia coli O157:H7 str. TW14359 8219877 YP_003081068.1 CDS ytfF NC_013008.1 5318826 5319791 R inner membrane protein complement(5318826..5319791) Escherichia coli O157:H7 str. TW14359 8219878 YP_003081069.1 CDS ytfG NC_013008.1 5319899 5320759 R NAD(P)H:quinone oxidoreductase complement(5319899..5320759) Escherichia coli O157:H7 str. TW14359 8219879 YP_003081070.1 CDS ytfH NC_013008.1 5320848 5321228 D transcriptional regulator 5320848..5321228 Escherichia coli O157:H7 str. TW14359 8219880 YP_003081071.1 CDS cpdB NC_013008.1 5321346 5323289 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(5321346..5323289) Escherichia coli O157:H7 str. TW14359 8219881 YP_003081072.1 CDS cysQ NC_013008.1 5323479 5324219 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 5323479..5324219 Escherichia coli O157:H7 str. TW14359 8219882 YP_003081073.1 CDS ytfI NC_013008.1 5324431 5325369 D hypothetical protein 5324431..5325369 Escherichia coli O157:H7 str. TW14359 8219883 YP_003081074.1 CDS ytfJ NC_013008.1 5325432 5325986 R transcriptional regulator complement(5325432..5325986) Escherichia coli O157:H7 str. TW14359 8219884 YP_003081075.1 CDS ytfK NC_013008.1 5326311 5326517 D hypothetical protein 5326311..5326517 Escherichia coli O157:H7 str. TW14359 8219885 YP_003081076.1 CDS ytfL NC_013008.1 5326596 5327939 R inner membrane protein complement(5326596..5327939) Escherichia coli O157:H7 str. TW14359 8219886 YP_003081077.1 CDS msrA NC_013008.1 5328262 5328900 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(5328262..5328900) Escherichia coli O157:H7 str. TW14359 8219887 YP_003081078.1 CDS ytfM NC_013008.1 5329106 5330839 D outer membrane protein and surface antigen 5329106..5330839 Escherichia coli O157:H7 str. TW14359 8219888 YP_003081079.1 CDS ytfN NC_013008.1 5330836 5334615 D hypothetical protein 5330836..5334615 Escherichia coli O157:H7 str. TW14359 8219889 YP_003081080.1 CDS ytfP NC_013008.1 5334618 5334959 D hypothetical protein 5334618..5334959 Escherichia coli O157:H7 str. TW14359 8219890 YP_003081081.1 CDS chpS NC_013008.1 5335171 5335422 D part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 5335171..5335422 Escherichia coli O157:H7 str. TW14359 8219891 YP_003081082.1 CDS chpB NC_013008.1 5335416 5335766 D toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 5335416..5335766 Escherichia coli O157:H7 str. TW14359 8219892 YP_003081083.1 CDS ppa NC_013008.1 5335846 5336376 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(5335846..5336376) Escherichia coli O157:H7 str. TW14359 8219893 YP_003081084.1 CDS ytfQ NC_013008.1 5336686 5337642 D sugar ABC transporter periplasmic-binding protein 5336686..5337642 Escherichia coli O157:H7 str. TW14359 8219894 YP_003081085.1 CDS ytfR NC_013008.1 5337782 5338474 D sugar ABC transporter ATP-binding protein 5337782..5338474 Escherichia coli O157:H7 str. TW14359 8219895 YP_003081086.1 CDS ytfT NC_013008.1 5339295 5340320 D sugar ABC transporter membrane protein 5339295..5340320 Escherichia coli O157:H7 str. TW14359 8219896 YP_003081087.1 CDS yjfF NC_013008.1 5340307 5341302 D membrane component of a sugar ABC transporter system; ABC transporter permease 5340307..5341302 Escherichia coli O157:H7 str. TW14359 8219897 YP_003081088.1 CDS fbp NC_013008.1 5341335 5342333 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(5341335..5342333) Escherichia coli O157:H7 str. TW14359 8219898 YP_003081089.1 CDS mpl NC_013008.1 5342509 5343882 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- me so-diaminopimelate ligase 5342509..5343882 Escherichia coli O157:H7 str. TW14359 8219899 YP_003081090.1 CDS yjgA NC_013008.1 5344038 5344589 R hypothetical protein complement(5344038..5344589) Escherichia coli O157:H7 str. TW14359 8219900 YP_003081091.1 CDS pmbA NC_013008.1 5344683 5346035 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 5344683..5346035 Escherichia coli O157:H7 str. TW14359 8219901 YP_003081092.1 CDS ECSP_5336 NC_013008.1 5346219 5346605 D soluble cytochrome b562 5346219..5346605 Escherichia coli O157:H7 str. TW14359 8219902 YP_003081093.1 CDS nrdG NC_013008.1 5346650 5347114 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(5346650..5347114) Escherichia coli O157:H7 str. TW14359 8219903 YP_003081094.1 CDS ECSP_5338 NC_013008.1 5347103 5347297 D hypothetical protein 5347103..5347297 Escherichia coli O157:H7 str. TW14359 8219904 YP_003081095.1 CDS nrdD NC_013008.1 5347304 5349442 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(5347304..5349442) Escherichia coli O157:H7 str. TW14359 8219905 YP_003081096.1 CDS treC NC_013008.1 5349836 5351491 R trehalose-6-phosphate hydrolase complement(5349836..5351491) Escherichia coli O157:H7 str. TW14359 8219906 YP_003081097.1 CDS treB NC_013008.1 5351541 5352962 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC complement(5351541..5352962) Escherichia coli O157:H7 str. TW14359 8219907 YP_003081098.1 CDS treR NC_013008.1 5353081 5354028 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(5353081..5354028) Escherichia coli O157:H7 str. TW14359 8219908 YP_003081099.1 CDS ECSP_5343 NC_013008.1 5354078 5354266 D hypothetical protein 5354078..5354266 Escherichia coli O157:H7 str. TW14359 8219909 YP_003081100.1 CDS mgtA NC_013008.1 5354407 5357103 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 5354407..5357103 Escherichia coli O157:H7 str. TW14359 8219910 YP_003081101.1 CDS yjgF NC_013008.1 5357309 5357695 R ketoacid-binding protein complement(5357309..5357695) Escherichia coli O157:H7 str. TW14359 8219911 YP_003081102.1 CDS pyrI NC_013008.1 5357768 5358229 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(5357768..5358229) Escherichia coli O157:H7 str. TW14359 8219912 YP_003081103.1 CDS pyrB NC_013008.1 5358242 5359177 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(5358242..5359177) Escherichia coli O157:H7 str. TW14359 8219913 YP_003081104.1 CDS ECSP_5348 NC_013008.1 5359181 5359372 R pyrBI operon leader peptide complement(5359181..5359372) Escherichia coli O157:H7 str. TW14359 8219914 YP_003081105.1 CDS ECSP_5349 NC_013008.1 5359354 5359491 R hypothetical protein complement(5359354..5359491) Escherichia coli O157:H7 str. TW14359 8219915 YP_003081106.1 CDS yjgH NC_013008.1 5359596 5359991 R mRNA endoribonuclease complement(5359596..5359991) Escherichia coli O157:H7 str. TW14359 8219916 YP_003081107.1 CDS yjgI NC_013008.1 5360122 5360835 R oxidoreductase complement(5360122..5360835) Escherichia coli O157:H7 str. TW14359 8219917 YP_003081108.1 CDS yjgJ NC_013008.1 5360906 5361499 D transcriptional regulator 5360906..5361499 Escherichia coli O157:H7 str. TW14359 8219918 YP_003081109.1 CDS yjgK NC_013008.1 5361644 5362096 D hypothetical protein 5361644..5362096 Escherichia coli O157:H7 str. TW14359 8219919 YP_003081110.1 CDS yjgL NC_013008.1 5362219 5363955 D hypothetical protein 5362219..5363955 Escherichia coli O157:H7 str. TW14359 8219920 YP_003081111.1 CDS argI NC_013008.1 5364012 5365016 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(5364012..5365016) Escherichia coli O157:H7 str. TW14359 8219921 YP_003081112.1 CDS rraB NC_013008.1 5365178 5365594 D hypothetical protein 5365178..5365594 Escherichia coli O157:H7 str. TW14359 8219922 YP_003081113.1 CDS yjgM NC_013008.1 5365640 5366143 R acetyltransferase complement(5365640..5366143) Escherichia coli O157:H7 str. TW14359 8219923 YP_003081114.1 CDS yjgN NC_013008.1 5366336 5367532 D hypothetical protein 5366336..5367532 Escherichia coli O157:H7 str. TW14359 8219924 YP_003081115.1 CDS valS NC_013008.1 5367587 5370442 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(5367587..5370442) Escherichia coli O157:H7 str. TW14359 8219925 YP_003081116.1 CDS holC NC_013008.1 5370442 5370885 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(5370442..5370885) Escherichia coli O157:H7 str. TW14359 8219926 YP_003081117.1 CDS pepA NC_013008.1 5371239 5372750 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(5371239..5372750) Escherichia coli O157:H7 str. TW14359 8219927 YP_003081118.1 CDS yjgP NC_013008.1 5373017 5374117 D hypothetical protein 5373017..5374117 Escherichia coli O157:H7 str. TW14359 8219928 YP_003081119.1 CDS yjgQ NC_013008.1 5374117 5375199 D hypothetical protein 5374117..5375199 Escherichia coli O157:H7 str. TW14359 8219929 YP_003081120.1 CDS yjgR NC_013008.1 5375360 5376862 R ATPase complement(5375360..5376862) Escherichia coli O157:H7 str. TW14359 8219930 YP_003081121.1 CDS yjgB NC_013008.1 5376992 5378011 R alcohol dehydrogenase, Zn-dependent and NAD(P)-binding complement(5376992..5378011) Escherichia coli O157:H7 str. TW14359 8219931 YP_003081122.1 CDS ECSP_5367 NC_013008.1 5378382 5380301 D integrase 5378382..5380301 Escherichia coli O157:H7 str. TW14359 8219933 YP_003081123.1 CDS ECSP_5368 NC_013008.1 5380428 5380805 R hypothetical protein complement(5380428..5380805) Escherichia coli O157:H7 str. TW14359 8219934 YP_003081124.1 CDS ECSP_5369 NC_013008.1 5380927 5381193 R hypothetical protein complement(5380927..5381193) Escherichia coli O157:H7 str. TW14359 8219935 YP_003081125.1 CDS ECSP_5370 NC_013008.1 5382263 5382730 R hypothetical protein complement(5382263..5382730) Escherichia coli O157:H7 str. TW14359 8219936 YP_003081126.1 CDS ECSP_5371 NC_013008.1 5382917 5383492 D resolvase 5382917..5383492 Escherichia coli O157:H7 str. TW14359 8219937 YP_003081127.1 CDS ECSP_5372 NC_013008.1 5383691 5385007 R hypothetical protein complement(5383691..5385007) Escherichia coli O157:H7 str. TW14359 8219938 YP_003081128.1 CDS ECSP_5373 NC_013008.1 5385159 5385932 R hypothetical protein complement(5385159..5385932) Escherichia coli O157:H7 str. TW14359 8219939 YP_003081129.1 CDS ECSP_5374 NC_013008.1 5386049 5386513 D hypothetical protein 5386049..5386513 Escherichia coli O157:H7 str. TW14359 8219940 YP_003081130.1 CDS ECSP_5375 NC_013008.1 5386546 5386647 D hypothetical protein 5386546..5386647 Escherichia coli O157:H7 str. TW14359 8219941 YP_003081131.1 CDS ECSP_5376 NC_013008.1 5386669 5386782 D hypothetical protein 5386669..5386782 Escherichia coli O157:H7 str. TW14359 8219942 YP_003081132.1 CDS ECSP_5377 NC_013008.1 5387151 5388056 D integrase 5387151..5388056 Escherichia coli O157:H7 str. TW14359 8219943 YP_003081133.1 CDS ECSP_5378 NC_013008.1 5388170 5388283 D hypothetical protein 5388170..5388283 Escherichia coli O157:H7 str. TW14359 8219944 YP_003081134.1 CDS ECSP_5379 NC_013008.1 5388516 5389367 R hypothetical protein complement(5388516..5389367) Escherichia coli O157:H7 str. TW14359 8219945 YP_003081135.1 CDS ECSP_5380 NC_013008.1 5389354 5389677 R hypothetical protein complement(5389354..5389677) Escherichia coli O157:H7 str. TW14359 8219946 YP_003081136.1 CDS ECSP_5381 NC_013008.1 5389908 5391011 R hypothetical protein complement(5389908..5391011) Escherichia coli O157:H7 str. TW14359 8219947 YP_003081137.1 CDS ECSP_5382 NC_013008.1 5391015 5391722 R hypothetical protein complement(5391015..5391722) Escherichia coli O157:H7 str. TW14359 8219948 YP_003081138.1 CDS ECSP_5383 NC_013008.1 5391729 5393381 R hypothetical protein complement(5391729..5393381) Escherichia coli O157:H7 str. TW14359 8219949 YP_003081139.1 CDS ECSP_5384 NC_013008.1 5393599 5396952 D hypothetical protein 5393599..5396952 Escherichia coli O157:H7 str. TW14359 8219950 YP_003081140.1 CDS ECSP_5385 NC_013008.1 5396952 5403266 D hypothetical protein 5396952..5403266 Escherichia coli O157:H7 str. TW14359 8219951 YP_003081141.1 CDS ECSP_5386 NC_013008.1 5403490 5406348 D ATP-dependent helicase 5403490..5406348 Escherichia coli O157:H7 str. TW14359 8219952 YP_003081142.1 CDS ECSP_5387 NC_013008.1 5406351 5411285 D hypothetical protein 5406351..5411285 Escherichia coli O157:H7 str. TW14359 8219953 YP_003081143.1 CDS ECSP_5388 NC_013008.1 5411285 5417626 D helicase 5411285..5417626 Escherichia coli O157:H7 str. TW14359 8219954 YP_003081144.1 CDS ECSP_5389 NC_013008.1 5417623 5419737 D helicase 5417623..5419737 Escherichia coli O157:H7 str. TW14359 8219955 YP_003081145.1 CDS ECSP_5390 NC_013008.1 5420690 5420935 R hypothetical protein complement(5420690..5420935) Escherichia coli O157:H7 str. TW14359 8219956 YP_003081146.1 CDS yjhS NC_013008.1 5421231 5422211 R hypothetical protein complement(5421231..5422211) Escherichia coli O157:H7 str. TW14359 8219957 YP_003081147.1 CDS yjhT NC_013008.1 5422276 5423382 R N-acetylneuraminic acid mutarotase complement(5422276..5423382) Escherichia coli O157:H7 str. TW14359 8219958 YP_003081148.1 CDS yjhA NC_013008.1 5423402 5424118 R N-acetylnuraminic acid outer membrane channel protein complement(5423402..5424118) Escherichia coli O157:H7 str. TW14359 8219959 YP_003081149.1 CDS ECSP_5394 NC_013008.1 5424503 5424739 D hypothetical protein 5424503..5424739 Escherichia coli O157:H7 str. TW14359 8219960 YP_003081150.1 CDS ECSP_5395 NC_013008.1 5424783 5424920 R hypothetical protein complement(5424783..5424920) Escherichia coli O157:H7 str. TW14359 8219961 YP_003081151.1 CDS fimB NC_013008.1 5425574 5426176 D inversion of on/off regulator of fimA; tyrosine recombinase 5425574..5426176 Escherichia coli O157:H7 str. TW14359 8219962 YP_003081152.1 CDS fimE NC_013008.1 5426654 5427250 D inversion of on/off regulator of fimA; tyrosine recombinase 5426654..5427250 Escherichia coli O157:H7 str. TW14359 8219963 YP_003081153.1 CDS fimA NC_013008.1 5427715 5428263 D major type 1 subunit fimbrin 5427715..5428263 Escherichia coli O157:H7 str. TW14359 8219964 YP_003081154.1 CDS fimI NC_013008.1 5428328 5428867 D type 1 pilus biosynthesis fimbrial protein 5428328..5428867 Escherichia coli O157:H7 str. TW14359 8219965 YP_003081155.1 CDS fimC NC_013008.1 5428904 5429629 D periplasmic chaperone, required for type 1 fimbriae 5428904..5429629 Escherichia coli O157:H7 str. TW14359 8219966 YP_003081156.1 CDS fimD NC_013008.1 5429696 5432332 D outer membrane usher protein, type 1 fimbrial synthesis 5429696..5432332 Escherichia coli O157:H7 str. TW14359 8219967 YP_003081157.1 CDS fimF NC_013008.1 5432342 5432872 D fimbrial morphology 5432342..5432872 Escherichia coli O157:H7 str. TW14359 8219968 YP_003081158.1 CDS fimG NC_013008.1 5432885 5433388 D minor subunit of type 1 fimbriae 5432885..5433388 Escherichia coli O157:H7 str. TW14359 8219969 YP_003081159.1 CDS fimH NC_013008.1 5433408 5434310 D minor fimbrial subunit, D-mannose specific adhesin 5433408..5434310 Escherichia coli O157:H7 str. TW14359 8219970 YP_003081160.1 CDS gntP NC_013008.1 5434484 5435827 R fructuronate transporter complement(5434484..5435827) Escherichia coli O157:H7 str. TW14359 8219971 YP_003081161.1 CDS uxuA NC_013008.1 5436167 5437351 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5436167..5437351 Escherichia coli O157:H7 str. TW14359 8219972 YP_003081162.1 CDS uxuB NC_013008.1 5437432 5438892 D D-mannonate oxidoreductase, NAD-binding 5437432..5438892 Escherichia coli O157:H7 str. TW14359 8219973 YP_003081163.1 CDS uxuR NC_013008.1 5439107 5439880 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5439107..5439880 Escherichia coli O157:H7 str. TW14359 8219974 YP_003081164.1 CDS yjiC NC_013008.1 5440021 5440851 R hypothetical protein complement(5440021..5440851) Escherichia coli O157:H7 str. TW14359 8219975 YP_003081165.1 CDS ECSP_5410 NC_013008.1 5441185 5441328 D hypothetical protein 5441185..5441328 Escherichia coli O157:H7 str. TW14359 8219976 YP_003081166.1 CDS iraD NC_013008.1 5441524 5441916 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5441524..5441916 Escherichia coli O157:H7 str. TW14359 8219977 YP_003081167.1 CDS iadA NC_013008.1 5442885 5444057 R isoaspartyl dipeptidase complement(5442885..5444057) Escherichia coli O157:H7 str. TW14359 8219979 YP_003081168.1 CDS yjiG NC_013008.1 5444070 5444531 R hypothetical protein complement(5444070..5444531) Escherichia coli O157:H7 str. TW14359 8219980 YP_003081169.1 CDS yjiH NC_013008.1 5444528 5445211 R hypothetical protein complement(5444528..5445211) Escherichia coli O157:H7 str. TW14359 8219981 YP_003081170.1 CDS kptA NC_013008.1 5445359 5445805 D 2'-phosphotransferase 5445359..5445805 Escherichia coli O157:H7 str. TW14359 8219982 YP_003081171.1 CDS ECSP_5417 NC_013008.1 5446168 5451204 R invasin complement(5446168..5451204) Escherichia coli O157:H7 str. TW14359 8219983 YP_003081172.1 CDS yjiJ NC_013008.1 5451620 5452798 R inner membrane protein complement(5451620..5452798) Escherichia coli O157:H7 str. TW14359 8219984 YP_003081173.1 CDS yjiK NC_013008.1 5452866 5453855 R hypothetical protein complement(5452866..5453855) Escherichia coli O157:H7 str. TW14359 8219985 YP_003081174.1 CDS espX6 NC_013008.1 5453974 5456157 R non-LEE-encoded type III effector complement(5453974..5456157) Escherichia coli O157:H7 str. TW14359 8219986 YP_003081175.1 CDS yjiL NC_013008.1 5456732 5457499 R ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase complement(5456732..5457499) Escherichia coli O157:H7 str. TW14359 8219987 YP_003081176.1 CDS yjiM NC_013008.1 5457509 5458660 R 2-hydroxyglutaryl-CoA dehydratase complement(5457509..5458660) Escherichia coli O157:H7 str. TW14359 8219988 YP_003081177.1 CDS yjiN NC_013008.1 5458776 5460047 R hypothetical protein complement(5458776..5460047) Escherichia coli O157:H7 str. TW14359 8219989 YP_003081178.1 CDS yjiO NC_013008.1 5460088 5461320 R multidrug efflux system protein complement(5460088..5461320) Escherichia coli O157:H7 str. TW14359 8219990 YP_003081179.1 CDS yjiR NC_013008.1 5462987 5464399 R fused DNA-binding transcriptional regulator, aminotransferase complement(5462987..5464399) Escherichia coli O157:H7 str. TW14359 8219992 YP_003081180.1 CDS yjiS NC_013008.1 5464576 5464740 D hypothetical protein 5464576..5464740 Escherichia coli O157:H7 str. TW14359 8219993 YP_003081181.1 CDS yjiW NC_013008.1 5466976 5467317 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(5466976..5467317) Escherichia coli O157:H7 str. TW14359 8219995 YP_003081182.1 CDS ECSP_5430 NC_013008.1 5467538 5469292 R restriction modification enzyme S subunit complement(5467538..5469292) Escherichia coli O157:H7 str. TW14359 8219996 YP_003081183.1 CDS ECSP_5431 NC_013008.1 5469292 5470773 R restriction modification enzyme M subunit (methylase) complement(5469292..5470773) Escherichia coli O157:H7 str. TW14359 8219997 YP_003081184.1 CDS ECSP_5432 NC_013008.1 5470828 5473260 R restriction modification enzyme R subunit (endonuclease) complement(5470828..5473260) Escherichia coli O157:H7 str. TW14359 8219998 YP_003081185.1 CDS yjiA NC_013008.1 5475258 5476214 R GTP-binding protein YjiA complement(5475258..5476214) Escherichia coli O157:H7 str. TW14359 8220000 YP_003081186.1 CDS yjiX NC_013008.1 5476225 5476428 R hypothetical protein complement(5476225..5476428) Escherichia coli O157:H7 str. TW14359 8220001 YP_003081187.1 CDS yjiY NC_013008.1 5476478 5478628 R inner membrane protein complement(5476478..5478628) Escherichia coli O157:H7 str. TW14359 8220002 YP_003081188.1 CDS ECSP_5437 NC_013008.1 5478921 5479463 R hypothetical protein complement(5478921..5479463) Escherichia coli O157:H7 str. TW14359 8220003 YP_003081189.1 CDS tsr NC_013008.1 5479692 5481356 D methyl-accepting chemotaxis protein I, serine sensor receptor 5479692..5481356 Escherichia coli O157:H7 str. TW14359 8220004 YP_003081190.1 CDS yjiZ NC_013008.1 5481405 5482766 R transporter complement(5481405..5482766) Escherichia coli O157:H7 str. TW14359 8220005 YP_003081191.1 CDS yjjM NC_013008.1 5482981 5483895 R DNA-binding transcriptional regulator complement(5482981..5483895) Escherichia coli O157:H7 str. TW14359 8220006 YP_003081192.1 CDS yjjN NC_013008.1 5484034 5485056 D oxidoreductase 5484034..5485056 Escherichia coli O157:H7 str. TW14359 8220007 YP_003081193.1 CDS mdoB NC_013008.1 5485193 5487484 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(5485193..5487484) Escherichia coli O157:H7 str. TW14359 8220008 YP_003081194.1 CDS yjjA NC_013008.1 5487738 5488232 R hypothetical protein complement(5487738..5488232) Escherichia coli O157:H7 str. TW14359 8220009 YP_003081195.1 CDS dnaC NC_013008.1 5488281 5489018 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(5488281..5489018) Escherichia coli O157:H7 str. TW14359 8220010 YP_003081196.1 CDS dnaT NC_013008.1 5489021 5489560 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(5489021..5489560) Escherichia coli O157:H7 str. TW14359 8220011 YP_003081197.1 CDS yjjB NC_013008.1 5489667 5490140 R hypothetical protein complement(5489667..5490140) Escherichia coli O157:H7 str. TW14359 8220012 YP_003081198.1 CDS yjjP NC_013008.1 5490131 5490901 R inner membrane protein complement(5490131..5490901) Escherichia coli O157:H7 str. TW14359 8220013 YP_003081199.1 CDS yjjQ NC_013008.1 5491522 5492247 D DNA-binding transcriptional regulator 5491522..5492247 Escherichia coli O157:H7 str. TW14359 8220014 YP_003081200.1 CDS bglJ NC_013008.1 5492355 5492882 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5492355..5492882 Escherichia coli O157:H7 str. TW14359 8220015 YP_003081201.1 CDS fhuF NC_013008.1 5492920 5493708 R ferric iron reductase involved in ferric hydroximate transport complement(5492920..5493708) Escherichia coli O157:H7 str. TW14359 8220016 YP_003081202.1 CDS ECSP_5451 NC_013008.1 5493810 5494085 D hypothetical protein 5493810..5494085 Escherichia coli O157:H7 str. TW14359 8220017 YP_003081203.1 CDS rsmC NC_013008.1 5494400 5495431 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(5494400..5495431) Escherichia coli O157:H7 str. TW14359 8220019 YP_003081204.1 CDS holD NC_013008.1 5495534 5495947 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5495534..5495947 Escherichia coli O157:H7 str. TW14359 8220020 YP_003081205.1 CDS rimI NC_013008.1 5495916 5496362 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5495916..5496362 Escherichia coli O157:H7 str. TW14359 8220021 YP_003081206.1 CDS yjjG NC_013008.1 5496377 5497054 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5496377..5497054 Escherichia coli O157:H7 str. TW14359 8220022 YP_003081207.1 CDS prfC NC_013008.1 5497145 5498734 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5497145..5498734 Escherichia coli O157:H7 str. TW14359 8220023 YP_003081208.1 CDS osmY NC_013008.1 5499127 5499732 D periplasmic protein 5499127..5499732 Escherichia coli O157:H7 str. TW14359 8220024 YP_003081209.1 CDS ytjA NC_013008.1 5499859 5500020 D hypothetical protein 5499859..5500020 Escherichia coli O157:H7 str. TW14359 8220025 YP_003081210.1 CDS yjjU NC_013008.1 5500142 5501215 D esterase 5500142..5501215 Escherichia coli O157:H7 str. TW14359 8220026 YP_003081211.1 CDS yjjV NC_013008.1 5501212 5501994 D deoxyribonuclease YjjV 5501212..5501994 Escherichia coli O157:H7 str. TW14359 8220027 YP_003081212.1 CDS yjjW NC_013008.1 5502208 5503071 R pyruvate formate lyase activating enzyme complement(5502208..5503071) Escherichia coli O157:H7 str. TW14359 8220028 YP_003081213.1 CDS yjjI NC_013008.1 5503324 5504592 R hypothetical protein complement(5503324..5504592) Escherichia coli O157:H7 str. TW14359 8220029 YP_003081214.1 CDS deoC NC_013008.1 5504850 5505629 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5504850..5505629 Escherichia coli O157:H7 str. TW14359 8220030 YP_003081215.1 CDS deoA NC_013008.1 5505756 5507078 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5505756..5507078 Escherichia coli O157:H7 str. TW14359 8220031 YP_003081216.1 CDS deoB NC_013008.1 5507130 5508353 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5507130..5508353 Escherichia coli O157:H7 str. TW14359 8220032 YP_003081217.1 CDS deoD NC_013008.1 5508410 5509129 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5508410..5509129 Escherichia coli O157:H7 str. TW14359 8220033 YP_003081218.1 CDS ECSP_5468 NC_013008.1 5509290 5509553 R DNA binding protein complement(5509290..5509553) Escherichia coli O157:H7 str. TW14359 8220034 YP_003081219.1 CDS ECSP_5469 NC_013008.1 5509585 5511273 R in E. coli the lipoate ligase A catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes; creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; unknown domain/lipoate-protein ligase A fusion protein complement(5509585..5511273) Escherichia coli O157:H7 str. TW14359 8220035 YP_003081220.1 CDS serB NC_013008.1 5511379 5512347 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5511379..5512347 Escherichia coli O157:H7 str. TW14359 8220036 YP_003081221.1 CDS radA NC_013008.1 5512396 5513778 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5512396..5513778 Escherichia coli O157:H7 str. TW14359 8220037 YP_003081222.1 CDS nadR NC_013008.1 5513799 5515031 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5513799..5515031 Escherichia coli O157:H7 str. TW14359 8220038 YP_003081223.1 CDS ECSP_5473 NC_013008.1 5515065 5515232 D lipid A biosynthesis protein 5515065..5515232 Escherichia coli O157:H7 str. TW14359 8220039 YP_003081224.1 CDS yjjK NC_013008.1 5515339 5517006 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(5515339..5517006) Escherichia coli O157:H7 str. TW14359 8220040 YP_003081225.1 CDS slt NC_013008.1 5517217 5519154 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5517217..5519154 Escherichia coli O157:H7 str. TW14359 8220041 YP_003081226.1 CDS trpR NC_013008.1 5519244 5519570 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5519244..5519570 Escherichia coli O157:H7 str. TW14359 8220042 YP_003081227.1 CDS yjjX NC_013008.1 5519717 5520229 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(5519717..5520229) Escherichia coli O157:H7 str. TW14359 8220043 YP_003081228.1 CDS ytjC NC_013008.1 5520281 5520928 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5520281..5520928 Escherichia coli O157:H7 str. TW14359 8220044 YP_003081229.1 CDS rob NC_013008.1 5520925 5521794 R DNA-binding transcriptional activator complement(5520925..5521794) Escherichia coli O157:H7 str. TW14359 8220045 YP_003081230.1 CDS creA NC_013008.1 5522005 5522478 D hypothetical protein 5522005..5522478 Escherichia coli O157:H7 str. TW14359 8220046 YP_003081231.1 CDS creB NC_013008.1 5522491 5523180 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5522491..5523180 Escherichia coli O157:H7 str. TW14359 8220047 YP_003081232.1 CDS creC NC_013008.1 5523180 5524604 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5523180..5524604 Escherichia coli O157:H7 str. TW14359 8220048 YP_003081233.1 CDS ECSP_5483 NC_013008.1 5524662 5526014 D hypothetical protein 5524662..5526014 Escherichia coli O157:H7 str. TW14359 8220049 YP_003081234.1 CDS ECSP_5484 NC_013008.1 5526074 5526790 R two-component response regulator complement(5526074..5526790) Escherichia coli O157:H7 str. TW14359 8220050 YP_003081235.1 CDS ECSP_5485 NC_013008.1 5526886 5527026 D hypothetical protein 5526886..5527026 Escherichia coli O157:H7 str. TW14359 8220051 YP_003081236.1 CDS ECSP_5486 NC_013008.1 5527426 5528112 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5527426..5528112 Escherichia coli O157:H7 str. TW14359 8220052 YP_003082135.1 CDS tagA NC_013010.1 1 2685 D hypothetical protein 1..2685 Escherichia coli O157:H7 str. TW14359 8206983 YP_003082136.1 CDS etpC NC_013010.1 2772 3647 D type II secretion protein 2772..3647 Escherichia coli O157:H7 str. TW14359 8206874 YP_003082137.1 CDS etpD NC_013010.1 3663 5615 D type II secretion protein 3663..5615 Escherichia coli O157:H7 str. TW14359 8206875 YP_003082138.1 CDS etpE NC_013010.1 5615 7120 D type II secretion protein 5615..7120 Escherichia coli O157:H7 str. TW14359 8206876 YP_003082139.1 CDS etpF NC_013010.1 7122 8345 D type II secretion protein 7122..8345 Escherichia coli O157:H7 str. TW14359 8206877 YP_003082140.1 CDS etpG NC_013010.1 8376 8810 D type II secretion protein 8376..8810 Escherichia coli O157:H7 str. TW14359 8206878 YP_003082141.1 CDS etpH NC_013010.1 8807 9361 D type II secretion protein 8807..9361 Escherichia coli O157:H7 str. TW14359 8206879 YP_003082142.1 CDS etpI NC_013010.1 9376 9723 D type II secretion protein 9376..9723 Escherichia coli O157:H7 str. TW14359 8206880 YP_003082143.1 CDS etpJ NC_013010.1 9720 10319 D type II secretion protein 9720..10319 Escherichia coli O157:H7 str. TW14359 8206881 YP_003082144.1 CDS etpK NC_013010.1 10316 11293 D type II secretion protein 10316..11293 Escherichia coli O157:H7 str. TW14359 8206882 YP_003082145.1 CDS etpL NC_013010.1 11407 12504 D type II secretion protein 11407..12504 Escherichia coli O157:H7 str. TW14359 8206883 YP_003082146.1 CDS etpM NC_013010.1 12491 13003 D type II secretion protein 12491..13003 Escherichia coli O157:H7 str. TW14359 8206884 YP_003082147.1 CDS etpN NC_013010.1 13061 13894 D type II secretion protein 13061..13894 Escherichia coli O157:H7 str. TW14359 8206885 YP_003082148.1 CDS etpO NC_013010.1 13989 14387 D type II secretion protein 13989..14387 Escherichia coli O157:H7 str. TW14359 8206886 YP_003082149.1 CDS ECSP_6015 NC_013010.1 14566 14871 D hypothetical protein 14566..14871 Escherichia coli O157:H7 str. TW14359 8206887 YP_003082150.1 CDS ECSP_6016 NC_013010.1 14898 15737 D hypothetical protein 14898..15737 Escherichia coli O157:H7 str. TW14359 8206888 YP_003082151.1 CDS hlyC NC_013010.1 16278 16793 D hemolysin transport protein 16278..16793 Escherichia coli O157:H7 str. TW14359 8206889 YP_003082152.1 CDS hlyA NC_013010.1 16795 19791 D hemolysin toxin protein 16795..19791 Escherichia coli O157:H7 str. TW14359 8206890 YP_003082153.1 CDS hlyB NC_013010.1 19841 21961 D hemolysin transport protein 19841..21961 Escherichia coli O157:H7 str. TW14359 8206891 YP_003082154.1 CDS hlyD NC_013010.1 21965 23404 D hemolysin transport protein 21965..23404 Escherichia coli O157:H7 str. TW14359 8206892 YP_003082155.1 CDS ECSP_6021 NC_013010.1 23471 23665 D hypothetical protein 23471..23665 Escherichia coli O157:H7 str. TW14359 8206893 YP_003082156.1 CDS ECSP_6022 NC_013010.1 23707 23979 D hypothetical protein 23707..23979 Escherichia coli O157:H7 str. TW14359 8206894 YP_003082157.1 CDS ECSP_6023 NC_013010.1 24148 24378 D hypothetical protein 24148..24378 Escherichia coli O157:H7 str. TW14359 8206895 YP_003082158.1 CDS ECSP_6024 NC_013010.1 24499 25239 D replication protein 24499..25239 Escherichia coli O157:H7 str. TW14359 8206896 YP_003082159.1 CDS ECSP_6025 NC_013010.1 25329 25448 D hypothetical protein 25329..25448 Escherichia coli O157:H7 str. TW14359 8206897 YP_003082160.1 CDS ECSP_6026 NC_013010.1 25524 26501 R replication protein complement(25524..26501) Escherichia coli O157:H7 str. TW14359 8206898 YP_003082161.1 CDS ECSP_6027 NC_013010.1 26494 26664 R hypothetical protein complement(26494..26664) Escherichia coli O157:H7 str. TW14359 8206899 YP_003082162.1 CDS ECSP_6028 NC_013010.1 26909 27109 R hypothetical protein complement(26909..27109) Escherichia coli O157:H7 str. TW14359 8206900 YP_003082163.1 CDS ECSP_6029 NC_013010.1 27106 27726 R hypothetical protein complement(27106..27726) Escherichia coli O157:H7 str. TW14359 8206901 YP_003082164.1 CDS ECSP_6030 NC_013010.1 27723 28322 R hypothetical protein complement(27723..28322) Escherichia coli O157:H7 str. TW14359 8206902 YP_003082165.1 CDS ECSP_6031 NC_013010.1 28347 28688 D hypothetical protein 28347..28688 Escherichia coli O157:H7 str. TW14359 8206903 YP_003082166.1 CDS ccdA NC_013010.1 28865 29083 D plasmid maintenance protein CcdA 28865..29083 Escherichia coli O157:H7 str. TW14359 8206904 YP_003082167.1 CDS ECSP_6033 NC_013010.1 29137 30024 R transposase complement(29137..30024) Escherichia coli O157:H7 str. TW14359 8206905 YP_003082168.1 CDS ECSP_6034 NC_013010.1 30024 30350 R transposase complement(30024..30350) Escherichia coli O157:H7 str. TW14359 8206906 YP_003082169.1 CDS ccdB NC_013010.1 30449 30703 D controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 30449..30703 Escherichia coli O157:H7 str. TW14359 8206907 YP_003082170.1 CDS redF NC_013010.1 30704 31510 D resolvase 30704..31510 Escherichia coli O157:H7 str. TW14359 8206908 YP_003082171.1 CDS tra6 NC_013010.1 32233 33120 R transposase complement(32233..33120) Escherichia coli O157:H7 str. TW14359 8206909 YP_003082172.1 CDS ECSP_6038 NC_013010.1 33120 33446 R hypothetical protein complement(33120..33446) Escherichia coli O157:H7 str. TW14359 8206910 YP_003082173.1 CDS ECSP_6039 NC_013010.1 33522 34277 D RepE; RepFIB; replication protein 33522..34277 Escherichia coli O157:H7 str. TW14359 8206911 YP_003082174.1 CDS sopA NC_013010.1 34865 36031 D plasmid-partitioning protein SopA 34865..36031 Escherichia coli O157:H7 str. TW14359 8206912 YP_003082175.1 CDS sopB NC_013010.1 36031 37002 D SopB; plasmid-partitioning protein 36031..37002 Escherichia coli O157:H7 str. TW14359 8206913 YP_003082176.1 CDS ECSP_6042 NC_013010.1 37697 38599 D hypothetical protein 37697..38599 Escherichia coli O157:H7 str. TW14359 8206914 YP_003082177.1 CDS ECSP_6043 NC_013010.1 38603 38908 D hypothetical protein 38603..38908 Escherichia coli O157:H7 str. TW14359 8206915 YP_003082178.1 CDS ECSP_6044 NC_013010.1 38985 39668 D putative methylase 38985..39668 Escherichia coli O157:H7 str. TW14359 8206916 YP_003082179.1 CDS ECSP_6045 NC_013010.1 39669 39890 D hypothetical protein 39669..39890 Escherichia coli O157:H7 str. TW14359 8206917 YP_003082180.1 CDS ECSP_6046 NC_013010.1 39904 40338 D hypothetical protein 39904..40338 Escherichia coli O157:H7 str. TW14359 8206918 YP_003082181.1 CDS ECSP_6047 NC_013010.1 40384 41160 D hypothetical protein 40384..41160 Escherichia coli O157:H7 str. TW14359 8206919 YP_003082182.1 CDS ECSP_6048 NC_013010.1 41033 41605 D hypothetical protein 41033..41605 Escherichia coli O157:H7 str. TW14359 8206920 YP_003082183.1 CDS ECSP_6049 NC_013010.1 41578 42003 D hypothetical protein 41578..42003 Escherichia coli O157:H7 str. TW14359 8206921 YP_003082184.1 CDS ECSP_6050 NC_013010.1 42050 42472 D hypothetical protein 42050..42472 Escherichia coli O157:H7 str. TW14359 8206922 YP_003082185.1 CDS ECSP_6051 NC_013010.1 42469 42660 D hypothetical protein 42469..42660 Escherichia coli O157:H7 str. TW14359 8206923 YP_003082186.1 CDS ECSP_6052 NC_013010.1 42630 43160 R hypothetical protein complement(42630..43160) Escherichia coli O157:H7 str. TW14359 8206924 YP_003082187.1 CDS ECSP_6053 NC_013010.1 43304 43432 D hypothetical protein 43304..43432 Escherichia coli O157:H7 str. TW14359 8206925 YP_003082188.1 CDS ECSP_6054 NC_013010.1 43485 43634 R hypothetical protein complement(43485..43634) Escherichia coli O157:H7 str. TW14359 8206926 YP_003082189.1 CDS ECSP_6055 NC_013010.1 43656 43886 D hypothetical protein 43656..43886 Escherichia coli O157:H7 str. TW14359 8206927 YP_003082190.1 CDS ECSP_6056 NC_013010.1 43938 45299 D hypothetical protein 43938..45299 Escherichia coli O157:H7 str. TW14359 8206928 YP_003082191.1 CDS ECSP_6057 NC_013010.1 45346 45909 D hypothetical protein 45346..45909 Escherichia coli O157:H7 str. TW14359 8206929 YP_003082192.1 CDS ECSP_6058 NC_013010.1 45995 46444 R hypothetical protein complement(45995..46444) Escherichia coli O157:H7 str. TW14359 8206930 YP_003082193.1 CDS ssb NC_013010.1 46746 47198 D single-stranded DNA-binding protein 46746..47198 Escherichia coli O157:H7 str. TW14359 8206931 YP_003082194.1 CDS ECSP_6060 NC_013010.1 47255 47488 D hypothetical protein 47255..47488 Escherichia coli O157:H7 str. TW14359 8206932 YP_003082195.1 CDS ECSP_6061 NC_013010.1 47554 49512 D hypothetical protein 47554..49512 Escherichia coli O157:H7 str. TW14359 8206933 YP_003082196.1 CDS psiB NC_013010.1 49567 50001 D plasmid SOS inhibition protein B 49567..50001 Escherichia coli O157:H7 str. TW14359 8206934 YP_003082197.1 CDS psiA NC_013010.1 49998 50759 D PsiA; plasmid SOS inhibition protein A 49998..50759 Escherichia coli O157:H7 str. TW14359 8206935 YP_003082198.1 CDS flmA NC_013010.1 50991 51149 D small toxic polypeptide 50991..51149 Escherichia coli O157:H7 str. TW14359 8206936 YP_003082199.1 CDS ECSP_6065 NC_013010.1 51331 53304 D putative nickase 51331..53304 Escherichia coli O157:H7 str. TW14359 8206937 YP_003082200.1 CDS ECSP_6066 NC_013010.1 53408 53803 D hypothetical protein 53408..53803 Escherichia coli O157:H7 str. TW14359 8206938 YP_003082201.1 CDS ECSP_6067 NC_013010.1 54370 54759 R putative transposase complement(54370..54759) Escherichia coli O157:H7 str. TW14359 8206939 YP_003082202.1 CDS ECSP_6068 NC_013010.1 54911 55321 D transposase 54911..55321 Escherichia coli O157:H7 str. TW14359 8206940 YP_003082203.1 CDS ECSP_6069 NC_013010.1 55394 55483 D transposase 55394..55483 Escherichia coli O157:H7 str. TW14359 8206941 YP_003082204.1 CDS ECSP_6070 NC_013010.1 55590 65099 D putative cytotoxin 55590..65099 Escherichia coli O157:H7 str. TW14359 8206942 YP_003082205.1 CDS ECSP_6071 NC_013010.1 65191 65463 D putative transposase 65191..65463 Escherichia coli O157:H7 str. TW14359 8206943 YP_003082206.1 CDS ECSP_6072 NC_013010.1 65390 65893 R hypothetical protein complement(65390..65893) Escherichia coli O157:H7 str. TW14359 8206944 YP_003082207.1 CDS traI NC_013010.1 66040 67338 D DNA helicase 66040..67338 Escherichia coli O157:H7 str. TW14359 8206945 YP_003082208.1 CDS traX NC_013010.1 67358 68104 D conjugal transfer pilus acetylation protein TraX 67358..68104 Escherichia coli O157:H7 str. TW14359 8206946 YP_003082209.1 CDS ECSP_6075 NC_013010.1 68163 69023 D hypothetical protein 68163..69023 Escherichia coli O157:H7 str. TW14359 8206947 YP_003082210.1 CDS finO NC_013010.1 69051 69686 D conjugal transfer fertility inhibition protein FinO 69051..69686 Escherichia coli O157:H7 str. TW14359 8206948 YP_003082211.1 CDS ECSP_6077 NC_013010.1 69819 70031 D hypothetical protein 69819..70031 Escherichia coli O157:H7 str. TW14359 8206949 YP_003082212.1 CDS ECSP_6078 NC_013010.1 70216 70737 D hypothetical protein 70216..70737 Escherichia coli O157:H7 str. TW14359 8206950 YP_003082213.1 CDS ECSP_6079 NC_013010.1 70783 70992 D hemolysin expression-modulating protein 70783..70992 Escherichia coli O157:H7 str. TW14359 8206951 YP_003082214.1 CDS ECSP_6080 NC_013010.1 71030 71368 D hypothetical protein 71030..71368 Escherichia coli O157:H7 str. TW14359 8206952 YP_003082215.1 CDS ECSP_6081 NC_013010.1 71608 71862 D replication protein 71608..71862 Escherichia coli O157:H7 str. TW14359 8206953 YP_003082216.1 CDS ECSP_6082 NC_013010.1 72098 72172 D RepA6; leader peptide RepL 72098..72172 Escherichia coli O157:H7 str. TW14359 8206954 YP_003082217.1 CDS ECSP_6083 NC_013010.1 72153 73022 D RepA; replication protein 72153..73022 Escherichia coli O157:H7 str. TW14359 8206955 YP_003082218.1 CDS ECSP_6084 NC_013010.1 73384 73578 D replication protein 73384..73578 Escherichia coli O157:H7 str. TW14359 8206956 YP_003082219.1 CDS ECSP_6085 NC_013010.1 73998 74219 D hypothetical protein 73998..74219 Escherichia coli O157:H7 str. TW14359 8206957 YP_003082220.1 CDS ECSP_6086 NC_013010.1 74219 74494 D hypothetical protein 74219..74494 Escherichia coli O157:H7 str. TW14359 8206958 YP_003082221.1 CDS ECSP_6087 NC_013010.1 74565 74852 R hypothetical protein complement(74565..74852) Escherichia coli O157:H7 str. TW14359 8206959 YP_003082222.1 CDS ECSP_6088 NC_013010.1 74880 75101 R transposase complement(74880..75101) Escherichia coli O157:H7 str. TW14359 8206960 YP_003082223.1 CDS ECSP_6089 NC_013010.1 75154 75633 R hypothetical protein complement(75154..75633) Escherichia coli O157:H7 str. TW14359 8206961 YP_003082224.1 CDS ECSP_6090 NC_013010.1 75672 76181 R transposase complement(75672..76181) Escherichia coli O157:H7 str. TW14359 8206962 YP_003082225.1 CDS ECSP_6091 NC_013010.1 76166 76405 D hypothetical protein 76166..76405 Escherichia coli O157:H7 str. TW14359 8206963 YP_003082226.1 CDS katP NC_013010.1 76498 78708 D EHEC-catalase/peroxidase 76498..78708 Escherichia coli O157:H7 str. TW14359 8206964 YP_003082227.1 CDS ECSP_6093 NC_013010.1 78752 79141 D hypothetical protein 78752..79141 Escherichia coli O157:H7 str. TW14359 8206965 YP_003082228.1 CDS ECSP_6094 NC_013010.1 79147 79299 D hypothetical protein 79147..79299 Escherichia coli O157:H7 str. TW14359 8206966 YP_003082229.1 CDS ECSP_6095 NC_013010.1 79299 80186 D transposase 79299..80186 Escherichia coli O157:H7 str. TW14359 8206967 YP_003082230.1 CDS espP NC_013010.1 80367 84269 D putative exoprotein-precursor 80367..84269 Escherichia coli O157:H7 str. TW14359 8206968 YP_003082231.1 CDS ECSP_6097 NC_013010.1 84432 84572 R hypothetical protein complement(84432..84572) Escherichia coli O157:H7 str. TW14359 8206969 YP_003082232.1 CDS insA NC_013010.1 84734 85006 R transposase complement(84734..85006) Escherichia coli O157:H7 str. TW14359 8206970 YP_003082233.1 CDS ECSP_6099 NC_013010.1 85306 85428 D transposase 85306..85428 Escherichia coli O157:H7 str. TW14359 8206971 YP_003082234.1 CDS ECSP_6100 NC_013010.1 85691 85846 D regulatory protein 85691..85846 Escherichia coli O157:H7 str. TW14359 8206972 YP_003082235.1 CDS ECSP_6101 NC_013010.1 86061 86180 D hypothetical protein 86061..86180 Escherichia coli O157:H7 str. TW14359 8206973 YP_003082236.1 CDS ECSP_6102 NC_013010.1 86478 87269 D hypothetical protein 86478..87269 Escherichia coli O157:H7 str. TW14359 8206974 YP_003082237.1 CDS ECSP_6103 NC_013010.1 87272 88375 D hypothetical protein 87272..88375 Escherichia coli O157:H7 str. TW14359 8206975 YP_003082238.1 CDS ECSP_6104 NC_013010.1 88465 90186 D hypothetical protein 88465..90186 Escherichia coli O157:H7 str. TW14359 8206976 YP_003082239.1 CDS ECSP_6105 NC_013010.1 90227 91258 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 90227..91258 Escherichia coli O157:H7 str. TW14359 8206977 YP_003082240.1 CDS ECSP_6106 NC_013010.1 91626 92006 D transposase 91626..92006 Escherichia coli O157:H7 str. TW14359 8206978 YP_003082241.1 CDS ECSP_6107 NC_013010.1 92003 92350 D transposase 92003..92350 Escherichia coli O157:H7 str. TW14359 8206979 YP_003082242.1 CDS ECSP_6108 NC_013010.1 92400 93938 D transposase 92400..93938 Escherichia coli O157:H7 str. TW14359 8206980 YP_003082243.1 CDS ECSP_6109 NC_013010.1 94029 94145 R hypothetical protein complement(94029..94145) Escherichia coli O157:H7 str. TW14359 8206981 YP_003082244.1 CDS ECSP_6110 NC_013010.1 94312 94527 R hypothetical protein complement(94312..94527) Escherichia coli O157:H7 str. TW14359 8206982 ECSP_0201 tRNA ECSP_0201 NC_013008.1 228693 228769 D tRNA-Ile 228693..228769 Escherichia coli O157:H7 str. TW14359 8214767 ECSP_0202 tRNA ECSP_0202 NC_013008.1 228812 228887 D tRNA-Ala 228812..228887 Escherichia coli O157:H7 str. TW14359 8214768 ECSP_0205 tRNA ECSP_0205 NC_013008.1 232240 232316 D tRNA-Asp 232240..232316 Escherichia coli O157:H7 str. TW14359 8214771 ECSP_0215 tRNA ECSP_0215 NC_013008.1 240464 240540 D tRNA-Asp 240464..240540 Escherichia coli O157:H7 str. TW14359 8214781 ECSP_0278 tRNA ECSP_0278 NC_013008.1 302543 302618 D tRNA-Thr 302543..302618 Escherichia coli O157:H7 str. TW14359 8214844 ECSP_0610 tRNA ECSP_0610 NC_013008.1 662051 662127 D tRNA-Arg 662051..662127 Escherichia coli O157:H7 str. TW14359 8215176 ECSP_0714 tRNA ECSP_0714 NC_013008.1 781459 781533 R tRNA-Gln complement(781459..781533) Escherichia coli O157:H7 str. TW14359 8215280 ECSP_0715 tRNA ECSP_0715 NC_013008.1 781571 781645 R tRNA-Gln complement(781571..781645) Escherichia coli O157:H7 str. TW14359 8215281 ECSP_0716 tRNA ECSP_0716 NC_013008.1 781694 781770 R tRNA-Met complement(781694..781770) Escherichia coli O157:H7 str. TW14359 8215282 ECSP_0717 tRNA ECSP_0717 NC_013008.1 781786 781860 R tRNA-Gln complement(781786..781860) Escherichia coli O157:H7 str. TW14359 8215283 ECSP_0718 tRNA ECSP_0718 NC_013008.1 781895 781969 R tRNA-Gln complement(781895..781969) Escherichia coli O157:H7 str. TW14359 8215284 ECSP_0719 tRNA ECSP_0719 NC_013008.1 781993 782077 R tRNA-Leu complement(781993..782077) Escherichia coli O157:H7 str. TW14359 8215285 ECSP_0720 tRNA ECSP_0720 NC_013008.1 782088 782164 R tRNA-Met complement(782088..782164) Escherichia coli O157:H7 str. TW14359 8215286 ECSP_0796 tRNA ECSP_0796 NC_013008.1 869933 870008 D tRNA-Lys 869933..870008 Escherichia coli O157:H7 str. TW14359 8215362 ECSP_0797 tRNA ECSP_0797 NC_013008.1 870044 870119 D tRNA-Val 870044..870119 Escherichia coli O157:H7 str. TW14359 8215363 ECSP_0798 tRNA ECSP_0798 NC_013008.1 870122 870197 D tRNA-Lys 870122..870197 Escherichia coli O157:H7 str. TW14359 8215364 ECSP_0799 tRNA ECSP_0799 NC_013008.1 870249 870324 D tRNA-Val 870249..870324 Escherichia coli O157:H7 str. TW14359 8215365 ECSP_0800 tRNA ECSP_0800 NC_013008.1 870328 870403 D tRNA-Lys 870328..870403 Escherichia coli O157:H7 str. TW14359 8215366 ECSP_0801 tRNA ECSP_0801 NC_013008.1 870550 870625 D tRNA-Lys 870550..870625 Escherichia coli O157:H7 str. TW14359 8215367 ECSP_0988 tRNA ECSP_0988 NC_013008.1 1061910 1061997 R tRNA-Ser complement(1061910..1061997) Escherichia coli O157:H7 str. TW14359 8215554 ECSP_1104 tRNA ECSP_1104 NC_013008.1 1184359 1184434 D tRNA-Met 1184359..1184434 Escherichia coli O157:H7 str. TW14359 8215670 ECSP_1105 tRNA ECSP_1105 NC_013008.1 1184532 1184608 D tRNA-Arg 1184532..1184608 Escherichia coli O157:H7 str. TW14359 8215671 ECSP_1139 tRNA ECSP_1139 NC_013008.1 1216065 1216152 R tRNA-Ser complement(1216065..1216152) Escherichia coli O157:H7 str. TW14359 8215705 ECSP_1333 tRNA ECSP_1333 NC_013008.1 1400578 1400665 R tRNA-Ser complement(1400578..1400665) Escherichia coli O157:H7 str. TW14359 8215899 ECSP_1622 tRNA ECSP_1622 NC_013008.1 1652759 1652843 R tRNA-Tyr complement(1652759..1652843) Escherichia coli O157:H7 str. TW14359 8216188 ECSP_1623 tRNA ECSP_1623 NC_013008.1 1653053 1653137 R tRNA-Tyr complement(1653053..1653137) Escherichia coli O157:H7 str. TW14359 8216189 ECSP_1672 tRNA ECSP_1672 NC_013008.1 1694497 1694572 D tRNA-Met 1694497..1694572 Escherichia coli O157:H7 str. TW14359 8216238 ECSP_1673 tRNA ECSP_1673 NC_013008.1 1694653 1694729 D tRNA-Arg 1694653..1694729 Escherichia coli O157:H7 str. TW14359 8216239 ECSP_1743 tRNA ECSP_1743 NC_013008.1 1752658 1752732 D tRNA-Met 1752658..1752732 Escherichia coli O157:H7 str. TW14359 8216309 ECSP_2058 tRNA ECSP_2058 NC_013008.1 2096533 2096609 R tRNA-Arg complement(2096533..2096609) Escherichia coli O157:H7 str. TW14359 8216624 ECSP_2059 tRNA ECSP_2059 NC_013008.1 2096710 2096785 R tRNA-Met complement(2096710..2096785) Escherichia coli O157:H7 str. TW14359 8216625 ECSP_2118 tRNA ECSP_2118 NC_013008.1 2144448 2144524 R tRNA-Arg complement(2144448..2144524) Escherichia coli O157:H7 str. TW14359 8216684 ECSP_2119 tRNA ECSP_2119 NC_013008.1 2144538 2144614 R tRNA-Arg complement(2144538..2144614) Escherichia coli O157:H7 str. TW14359 8216685 ECSP_2120 tRNA ECSP_2120 NC_013008.1 2144622 2144697 R tRNA-Met complement(2144622..2144697) Escherichia coli O157:H7 str. TW14359 8216686 ECSP_2232 tRNA ECSP_2232 NC_013008.1 2251422 2251498 D tRNA-Val 2251422..2251498 Escherichia coli O157:H7 str. TW14359 8216798 ECSP_2233 tRNA ECSP_2233 NC_013008.1 2251503 2251579 D tRNA-Val 2251503..2251579 Escherichia coli O157:H7 str. TW14359 8216799 ECSP_2513 tRNA ECSP_2513 NC_013008.1 2520678 2520764 R tRNA-Leu complement(2520678..2520764) Escherichia coli O157:H7 str. TW14359 8217079 ECSP_2514 tRNA ECSP_2514 NC_013008.1 2520777 2520850 R tRNA-Cys complement(2520777..2520850) Escherichia coli O157:H7 str. TW14359 8217080 ECSP_2515 tRNA ECSP_2515 NC_013008.1 2520904 2520979 R tRNA-Gly complement(2520904..2520979) Escherichia coli O157:H7 str. TW14359 8217081 ECSP_2617 tRNA ECSP_2617 NC_013008.1 2604350 2604426 R tRNA-Arg complement(2604350..2604426) Escherichia coli O157:H7 str. TW14359 8217183 ECSP_2618 tRNA ECSP_2618 NC_013008.1 2604440 2604516 R tRNA-Arg complement(2604440..2604516) Escherichia coli O157:H7 str. TW14359 8217184 ECSP_2619 tRNA ECSP_2619 NC_013008.1 2604524 2604599 R tRNA-Met complement(2604524..2604599) Escherichia coli O157:H7 str. TW14359 8217185 ECSP_2638 tRNA ECSP_2638 NC_013008.1 2618642 2618731 R tRNA-Ser complement(2618642..2618731) Escherichia coli O157:H7 str. TW14359 8217204 ECSP_2640 tRNA ECSP_2640 NC_013008.1 2619723 2619798 D tRNA-Asn 2619723..2619798 Escherichia coli O157:H7 str. TW14359 8217206 ECSP_2648 tRNA ECSP_2648 NC_013008.1 2634103 2634178 R tRNA-Asn complement(2634103..2634178) Escherichia coli O157:H7 str. TW14359 8217214 ECSP_2650 tRNA ECSP_2650 NC_013008.1 2635927 2636002 D tRNA-Asn 2635927..2636002 Escherichia coli O157:H7 str. TW14359 8217216 ECSP_2654 tRNA ECSP_2654 NC_013008.1 2638335 2638410 D tRNA-Asn 2638335..2638410 Escherichia coli O157:H7 str. TW14359 8217220 ECSP_2724 tRNA ECSP_2724 NC_013008.1 2696516 2696592 R tRNA-Arg complement(2696516..2696592) Escherichia coli O157:H7 str. TW14359 8217290 ECSP_2725 tRNA ECSP_2725 NC_013008.1 2696606 2696682 R tRNA-Arg complement(2696606..2696682) Escherichia coli O157:H7 str. TW14359 8217291 ECSP_2726 tRNA ECSP_2726 NC_013008.1 2696684 2696759 R tRNA-Met complement(2696684..2696759) Escherichia coli O157:H7 str. TW14359 8217292 ECSP_2960 tRNA ECSP_2960 NC_013008.1 2918970 2919046 R tRNA-Arg complement(2918970..2919046) Escherichia coli O157:H7 str. TW14359 8217526 ECSP_2961 tRNA ECSP_2961 NC_013008.1 2919060 2919136 R tRNA-Arg complement(2919060..2919136) Escherichia coli O157:H7 str. TW14359 8217527 ECSP_2962 tRNA ECSP_2962 NC_013008.1 2919146 2919221 R tRNA-Met complement(2919146..2919221) Escherichia coli O157:H7 str. TW14359 8217528 ECSP_3070 tRNA ECSP_3070 NC_013008.1 3017374 3017450 D tRNA-Pro 3017374..3017450 Escherichia coli O157:H7 str. TW14359 8217636 ECSP_3254 tRNA ECSP_3254 NC_013008.1 3227209 3227285 R tRNA-Arg complement(3227209..3227285) Escherichia coli O157:H7 str. TW14359 8217820 ECSP_3255 tRNA ECSP_3255 NC_013008.1 3227299 3227375 R tRNA-Arg complement(3227299..3227375) Escherichia coli O157:H7 str. TW14359 8217821 ECSP_3256 tRNA ECSP_3256 NC_013008.1 3227383 3227458 R tRNA-Met complement(3227383..3227458) Escherichia coli O157:H7 str. TW14359 8217822 ECSP_3298 tRNA ECSP_3298 NC_013008.1 3251895 3251969 D tRNA-Arg 3251895..3251969 Escherichia coli O157:H7 str. TW14359 8217864 ECSP_3344 tRNA ECSP_3344 NC_013008.1 3303811 3303886 R tRNA-Ala complement(3303811..3303886) Escherichia coli O157:H7 str. TW14359 8217910 ECSP_3345 tRNA ECSP_3345 NC_013008.1 3303926 3304001 R tRNA-Ala complement(3303926..3304001) Escherichia coli O157:H7 str. TW14359 8217911 ECSP_3351 tRNA ECSP_3351 NC_013008.1 3308448 3308523 D tRNA-Val 3308448..3308523 Escherichia coli O157:H7 str. TW14359 8217917 ECSP_3352 tRNA ECSP_3352 NC_013008.1 3308568 3308643 D tRNA-Val 3308568..3308643 Escherichia coli O157:H7 str. TW14359 8217918 ECSP_3353 tRNA ECSP_3353 NC_013008.1 3308690 3308765 D tRNA-Val 3308690..3308765 Escherichia coli O157:H7 str. TW14359 8217919 ECSP_3354 tRNA ECSP_3354 NC_013008.1 3308770 3308845 D tRNA-Lys 3308770..3308845 Escherichia coli O157:H7 str. TW14359 8217920 ECSP_3537 tRNA ECSP_3537 NC_013008.1 3508560 3508635 R tRNA-Glu complement(3508560..3508635) Escherichia coli O157:H7 str. TW14359 8218103 ECSP_3602 tRNA ECSP_3602 NC_013008.1 3566908 3566983 R tRNA-Met complement(3566908..3566983) Escherichia coli O157:H7 str. TW14359 8218168 ECSP_3638 tRNA ECSP_3638 NC_013008.1 3600903 3600979 R tRNA-Arg complement(3600903..3600979) Escherichia coli O157:H7 str. TW14359 8218204 ECSP_3639 tRNA ECSP_3639 NC_013008.1 3601082 3601158 R tRNA-Arg complement(3601082..3601158) Escherichia coli O157:H7 str. TW14359 8218205 ECSP_3640 tRNA ECSP_3640 NC_013008.1 3601221 3601297 R tRNA-Arg complement(3601221..3601297) Escherichia coli O157:H7 str. TW14359 8218206 ECSP_3641 tRNA ECSP_3641 NC_013008.1 3601362 3601438 R tRNA-Arg complement(3601362..3601438) Escherichia coli O157:H7 str. TW14359 8218207 ECSP_3642 tRNA ECSP_3642 NC_013008.1 3601442 3601534 R tRNA-Ser complement(3601442..3601534) Escherichia coli O157:H7 str. TW14359 8218208 ECSP_3766 tRNA ECSP_3766 NC_013008.1 3728910 3728986 D tRNA-Met 3728910..3728986 Escherichia coli O157:H7 str. TW14359 8218332 ECSP_3767 tRNA ECSP_3767 NC_013008.1 3729020 3729096 D tRNA-Met 3729020..3729096 Escherichia coli O157:H7 str. TW14359 8218333 ECSP_3768 tRNA ECSP_3768 NC_013008.1 3729130 3729206 D tRNA-Met 3729130..3729206 Escherichia coli O157:H7 str. TW14359 8218334 ECSP_3834 tRNA ECSP_3834 NC_013008.1 3796437 3796510 R tRNA-Gly complement(3796437..3796510) Escherichia coli O157:H7 str. TW14359 8218400 ECSP_3939 tRNA ECSP_3939 NC_013008.1 3911083 3911158 D tRNA-Phe 3911083..3911158 Escherichia coli O157:H7 str. TW14359 8218505 ECSP_4043 tRNA ECSP_4043 NC_013008.1 4014253 4014328 D tRNA-Met 4014253..4014328 Escherichia coli O157:H7 str. TW14359 8218609 ECSP_4146 tRNA ECSP_4146 NC_013008.1 4118519 4118595 R tRNA-Met complement(4118519..4118595) Escherichia coli O157:H7 str. TW14359 8218712 ECSP_4149 tRNA ECSP_4149 NC_013008.1 4122378 4122464 R tRNA-Leu complement(4122378..4122464) Escherichia coli O157:H7 str. TW14359 8218715 ECSP_4244 tRNA ECSP_4244 NC_013008.1 4217706 4217781 R tRNA-Thr complement(4217706..4217781) Escherichia coli O157:H7 str. TW14359 8218810 ECSP_4247 tRNA ECSP_4247 NC_013008.1 4221092 4221167 R tRNA-Ala complement(4221092..4221167) Escherichia coli O157:H7 str. TW14359 8218813 ECSP_4248 tRNA ECSP_4248 NC_013008.1 4221210 4221286 R tRNA-Ile complement(4221210..4221286) Escherichia coli O157:H7 str. TW14359 8218814 ECSP_4536 tRNA ECSP_4536 NC_013008.1 4509585 4509661 R tRNA-Pro complement(4509585..4509661) Escherichia coli O157:H7 str. TW14359 8219102 ECSP_4808 tRNA ECSP_4808 NC_013008.1 4796017 4796092 D tRNA-Glu 4796017..4796092 Escherichia coli O157:H7 str. TW14359 8219374 ECSP_4811 tRNA ECSP_4811 NC_013008.1 4799455 4799531 D tRNA-Asp 4799455..4799531 Escherichia coli O157:H7 str. TW14359 8219377 ECSP_4812 tRNA ECSP_4812 NC_013008.1 4799540 4799615 D tRNA-Trp 4799540..4799615 Escherichia coli O157:H7 str. TW14359 8219378 ECSP_4845 tRNA ECSP_4845 NC_013008.1 4834919 4834995 D tRNA-Arg 4834919..4834995 Escherichia coli O157:H7 str. TW14359 8219411 ECSP_4846 tRNA ECSP_4846 NC_013008.1 4835054 4835129 D tRNA-His 4835054..4835129 Escherichia coli O157:H7 str. TW14359 8219412 ECSP_4847 tRNA ECSP_4847 NC_013008.1 4835150 4835236 D tRNA-Leu 4835150..4835236 Escherichia coli O157:H7 str. TW14359 8219413 ECSP_4848 tRNA ECSP_4848 NC_013008.1 4835280 4835353 D tRNA-Pro 4835280..4835353 Escherichia coli O157:H7 str. TW14359 8219414 ECSP_4849 tRNA ECSP_4849 NC_013008.1 4835376 4835462 D tRNA-Leu 4835376..4835462 Escherichia coli O157:H7 str. TW14359 8219415 ECSP_4850 tRNA ECSP_4850 NC_013008.1 4835505 4835581 D tRNA-Pro 4835505..4835581 Escherichia coli O157:H7 str. TW14359 8219416 ECSP_4905 tRNA ECSP_4905 NC_013008.1 4892439 4892515 D tRNA-Ile 4892439..4892515 Escherichia coli O157:H7 str. TW14359 8219471 ECSP_4906 tRNA ECSP_4906 NC_013008.1 4892558 4892633 D tRNA-Ala 4892558..4892633 Escherichia coli O157:H7 str. TW14359 8219472 ECSP_5040 tRNA ECSP_5040 NC_013008.1 5036727 5036802 D tRNA-Glu 5036727..5036802 Escherichia coli O157:H7 str. TW14359 8219606 ECSP_5046 tRNA ECSP_5046 NC_013008.1 5043578 5043653 D tRNA-Thr 5043578..5043653 Escherichia coli O157:H7 str. TW14359 8219612 ECSP_5047 tRNA ECSP_5047 NC_013008.1 5043662 5043746 D tRNA-Tyr 5043662..5043746 Escherichia coli O157:H7 str. TW14359 8219613 ECSP_5048 tRNA ECSP_5048 NC_013008.1 5043863 5043937 D tRNA-Gly 5043863..5043937 Escherichia coli O157:H7 str. TW14359 8219614 ECSP_5049 tRNA ECSP_5049 NC_013008.1 5043944 5044019 D tRNA-Thr 5043944..5044019 Escherichia coli O157:H7 str. TW14359 8219615 ECSP_5078 tRNA ECSP_5078 NC_013008.1 5077753 5077828 D tRNA-Glu 5077753..5077828 Escherichia coli O157:H7 str. TW14359 8219644 ECSP_5234 tRNA ECSP_5234 NC_013008.1 5248263 5248338 R tRNA-Phe complement(5248263..5248338) Escherichia coli O157:H7 str. TW14359 8219800 ECSP_5263 tRNA ECSP_5263 NC_013008.1 5277346 5277421 D tRNA-Gly 5277346..5277421 Escherichia coli O157:H7 str. TW14359 8219829 ECSP_5264 tRNA ECSP_5264 NC_013008.1 5277458 5277533 D tRNA-Gly 5277458..5277533 Escherichia coli O157:H7 str. TW14359 8219830 ECSP_5265 tRNA ECSP_5265 NC_013008.1 5277569 5277644 D tRNA-Gly 5277569..5277644 Escherichia coli O157:H7 str. TW14359 8219831 ECSP_5366 tRNA ECSP_5366 NC_013008.1 5378207 5378291 D tRNA-Leu 5378207..5378291 Escherichia coli O157:H7 str. TW14359 8219932 ECSP_5452 tRNA ECSP_5452 NC_013008.1 5494124 5494210 R tRNA-Leu complement(5494124..5494210) Escherichia coli O157:H7 str. TW14359 8220018 ECSP_0200 rRNA ECSP_0200 NC_013008.1 227083 228624 D 16S ribosomal RNA 227083..228624 Escherichia coli O157:H7 str. TW14359 8214766 ECSP_0203 rRNA ECSP_0203 NC_013008.1 229071 231975 D 23S ribosomal RNA 229071..231975 Escherichia coli O157:H7 str. TW14359 8214769 ECSP_0204 rRNA ECSP_0204 NC_013008.1 232068 232187 D 5S ribosomal RNA 232068..232187 Escherichia coli O157:H7 str. TW14359 8214770 ECSP_3535 rRNA ECSP_3535 NC_013008.1 3505252 3505371 R 5S ribosomal RNA complement(3505252..3505371) Escherichia coli O157:H7 str. TW14359 8218101 ECSP_3536 rRNA ECSP_3536 NC_013008.1 3505464 3508366 R 23S ribosomal RNA complement(3505464..3508366) Escherichia coli O157:H7 str. TW14359 8218102 ECSP_3538 rRNA ECSP_3538 NC_013008.1 3508721 3510262 R 16S ribosomal RNA complement(3508721..3510262) Escherichia coli O157:H7 str. TW14359 8218104 ECSP_4243 rRNA ECSP_4243 NC_013008.1 4217553 4217665 R 5S ribosomal RNA complement(4217553..4217665) Escherichia coli O157:H7 str. TW14359 8218809 ECSP_4245 rRNA ECSP_4245 NC_013008.1 4217794 4217913 R 5S ribosomal RNA complement(4217794..4217913) Escherichia coli O157:H7 str. TW14359 8218811 ECSP_4246 rRNA ECSP_4246 NC_013008.1 4218006 4220908 R 23S ribosomal RNA complement(4218006..4220908) Escherichia coli O157:H7 str. TW14359 8218812 ECSP_4249 rRNA ECSP_4249 NC_013008.1 4221355 4222896 R 16S ribosomal RNA complement(4221355..4222896) Escherichia coli O157:H7 str. TW14359 8218815 ECSP_4807 rRNA ECSP_4807 NC_013008.1 4794390 4795931 D 16S ribosomal RNA 4794390..4795931 Escherichia coli O157:H7 str. TW14359 8219373 ECSP_4809 rRNA ECSP_4809 NC_013008.1 4796286 4799190 D 23S ribosomal RNA 4796286..4799190 Escherichia coli O157:H7 str. TW14359 8219375 ECSP_4810 rRNA ECSP_4810 NC_013008.1 4799283 4799402 D 5S ribosomal RNA 4799283..4799402 Escherichia coli O157:H7 str. TW14359 8219376 ECSP_4904 rRNA ECSP_4904 NC_013008.1 4890829 4892370 D 16S ribosomal RNA 4890829..4892370 Escherichia coli O157:H7 str. TW14359 8219470 ECSP_4907 rRNA ECSP_4907 NC_013008.1 4892817 4895721 D 23S ribosomal RNA 4892817..4895721 Escherichia coli O157:H7 str. TW14359 8219473 ECSP_4908 rRNA ECSP_4908 NC_013008.1 4895814 4895933 D 5S ribosomal RNA 4895814..4895933 Escherichia coli O157:H7 str. TW14359 8219474 ECSP_5039 rRNA ECSP_5039 NC_013008.1 5035100 5036641 D 16S ribosomal RNA 5035100..5036641 Escherichia coli O157:H7 str. TW14359 8219605 ECSP_5041 rRNA ECSP_5041 NC_013008.1 5036996 5039900 D 23S ribosomal RNA 5036996..5039900 Escherichia coli O157:H7 str. TW14359 8219607 ECSP_5042 rRNA ECSP_5042 NC_013008.1 5039993 5040112 D 5S ribosomal RNA 5039993..5040112 Escherichia coli O157:H7 str. TW14359 8219608 ECSP_5077 rRNA ECSP_5077 NC_013008.1 5076126 5077667 D 16S ribosomal RNA 5076126..5077667 Escherichia coli O157:H7 str. TW14359 8219643 ECSP_5079 rRNA ECSP_5079 NC_013008.1 5078022 5080926 D 23S ribosomal RNA 5078022..5080926 Escherichia coli O157:H7 str. TW14359 8219645 ECSP_5080 rRNA ECSP_5080 NC_013008.1 5081019 5081138 D 5S ribosomal RNA 5081019..5081138 Escherichia coli O157:H7 str. TW14359 8219646