-- dump date   	20140619_090003
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
544404000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
544404000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
544404000003	putative catalytic residues [active]
544404000004	putative nucleotide binding site [chemical binding]; other site
544404000005	putative aspartate binding site [chemical binding]; other site
544404000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
544404000007	dimer interface [polypeptide binding]; other site
544404000008	putative threonine allosteric regulatory site; other site
544404000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
544404000010	putative threonine allosteric regulatory site; other site
544404000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
544404000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
544404000013	homoserine kinase; Region: thrB; TIGR00191
544404000014	Protein of unknown function; Region: YhfT; pfam10797
544404000015	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
544404000016	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
544404000017	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
544404000018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404000019	catalytic residue [active]
544404000020	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
544404000021	hypothetical protein; Validated; Region: PRK02101
544404000022	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
544404000023	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
544404000024	transaldolase-like protein; Provisional; Region: PTZ00411
544404000025	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
544404000026	active site
544404000027	dimer interface [polypeptide binding]; other site
544404000028	catalytic residue [active]
544404000029	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
544404000030	MPT binding site; other site
544404000031	trimer interface [polypeptide binding]; other site
544404000032	hypothetical protein; Provisional; Region: PRK10659
544404000033	hypothetical protein; Provisional; Region: PRK10236
544404000034	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
544404000035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
544404000036	hypothetical protein; Provisional; Region: PRK10154
544404000037	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
544404000038	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
544404000039	nucleotide binding site [chemical binding]; other site
544404000040	NEF interaction site [polypeptide binding]; other site
544404000041	SBD interface [polypeptide binding]; other site
544404000042	chaperone protein DnaJ; Provisional; Region: PRK10767
544404000043	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
544404000044	HSP70 interaction site [polypeptide binding]; other site
544404000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
544404000046	substrate binding site [polypeptide binding]; other site
544404000047	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
544404000048	Zn binding sites [ion binding]; other site
544404000049	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
544404000050	dimer interface [polypeptide binding]; other site
544404000051	Hok/gef family; Region: HOK_GEF; pfam01848
544404000052	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
544404000053	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
544404000054	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404000055	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
544404000056	putative dimerization interface [polypeptide binding]; other site
544404000057	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
544404000058	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404000059	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404000060	Fimbrial protein; Region: Fimbrial; cl01416
544404000061	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
544404000062	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
544404000063	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
544404000064	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
544404000065	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
544404000066	active site
544404000067	Riboflavin kinase; Region: Flavokinase; smart00904
544404000068	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
544404000069	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
544404000070	HIGH motif; other site
544404000071	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
544404000072	active site
544404000073	KMSKS motif; other site
544404000074	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
544404000075	tRNA binding surface [nucleotide binding]; other site
544404000076	anticodon binding site; other site
544404000077	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
544404000078	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
544404000079	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
544404000080	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
544404000081	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
544404000082	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
544404000083	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
544404000084	active site
544404000085	tetramer interface [polypeptide binding]; other site
544404000086	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
544404000087	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
544404000088	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
544404000089	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
544404000090	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
544404000091	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
544404000092	catalytic site [active]
544404000093	subunit interface [polypeptide binding]; other site
544404000094	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
544404000095	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
544404000096	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
544404000097	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
544404000098	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
544404000099	ATP-grasp domain; Region: ATP-grasp_4; cl17255
544404000100	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
544404000101	IMP binding site; other site
544404000102	dimer interface [polypeptide binding]; other site
544404000103	interdomain contacts; other site
544404000104	partial ornithine binding site; other site
544404000105	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
544404000106	carnitine operon protein CaiE; Provisional; Region: PRK13627
544404000107	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
544404000108	putative trimer interface [polypeptide binding]; other site
544404000109	putative metal binding site [ion binding]; other site
544404000110	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
544404000111	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
544404000112	substrate binding site [chemical binding]; other site
544404000113	oxyanion hole (OAH) forming residues; other site
544404000114	trimer interface [polypeptide binding]; other site
544404000115	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
544404000116	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
544404000117	acyl-activating enzyme (AAE) consensus motif; other site
544404000118	putative AMP binding site [chemical binding]; other site
544404000119	putative active site [active]
544404000120	putative CoA binding site [chemical binding]; other site
544404000121	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
544404000122	CoA-transferase family III; Region: CoA_transf_3; pfam02515
544404000123	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
544404000124	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
544404000125	active site
544404000126	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
544404000127	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
544404000128	Ligand binding site [chemical binding]; other site
544404000129	Electron transfer flavoprotein domain; Region: ETF; pfam01012
544404000130	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
544404000131	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
544404000132	Ligand binding site [chemical binding]; other site
544404000133	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
544404000134	putative oxidoreductase FixC; Provisional; Region: PRK10157
544404000135	ferredoxin-like protein FixX; Provisional; Region: PRK15449
544404000136	benzoate transport; Region: 2A0115; TIGR00895
544404000137	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404000138	putative substrate translocation pore; other site
544404000139	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
544404000140	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
544404000141	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
544404000142	TrkA-N domain; Region: TrkA_N; pfam02254
544404000143	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
544404000144	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
544404000145	folate binding site [chemical binding]; other site
544404000146	NADP+ binding site [chemical binding]; other site
544404000147	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
544404000148	CcdB protein; Region: CcdB; pfam01845
544404000149	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
544404000150	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
544404000151	active site
544404000152	metal binding site [ion binding]; metal-binding site
544404000153	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
544404000154	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
544404000155	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
544404000156	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
544404000157	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
544404000158	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
544404000159	SurA N-terminal domain; Region: SurA_N; pfam09312
544404000160	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
544404000161	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
544404000162	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
544404000163	OstA-like protein; Region: OstA; pfam03968
544404000164	Organic solvent tolerance protein; Region: OstA_C; pfam04453
544404000165	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
544404000166	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
544404000167	putative metal binding site [ion binding]; other site
544404000168	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
544404000169	HSP70 interaction site [polypeptide binding]; other site
544404000170	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
544404000171	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
544404000172	active site
544404000173	ATP-dependent helicase HepA; Validated; Region: PRK04914
544404000174	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404000175	ATP binding site [chemical binding]; other site
544404000176	putative Mg++ binding site [ion binding]; other site
544404000177	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404000178	nucleotide binding region [chemical binding]; other site
544404000179	ATP-binding site [chemical binding]; other site
544404000180	DNA polymerase II; Reviewed; Region: PRK05762
544404000181	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
544404000182	active site
544404000183	catalytic site [active]
544404000184	substrate binding site [chemical binding]; other site
544404000185	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
544404000186	active site
544404000187	metal-binding site
544404000188	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
544404000189	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
544404000190	intersubunit interface [polypeptide binding]; other site
544404000191	active site
544404000192	Zn2+ binding site [ion binding]; other site
544404000193	L-arabinose isomerase; Provisional; Region: PRK02929
544404000194	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
544404000195	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
544404000196	trimer interface [polypeptide binding]; other site
544404000197	putative substrate binding site [chemical binding]; other site
544404000198	putative metal binding site [ion binding]; other site
544404000199	ribulokinase; Provisional; Region: PRK04123
544404000200	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
544404000201	N- and C-terminal domain interface [polypeptide binding]; other site
544404000202	active site
544404000203	MgATP binding site [chemical binding]; other site
544404000204	catalytic site [active]
544404000205	metal binding site [ion binding]; metal-binding site
544404000206	carbohydrate binding site [chemical binding]; other site
544404000207	homodimer interface [polypeptide binding]; other site
544404000208	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
544404000209	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
544404000210	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404000211	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404000212	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
544404000213	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
544404000214	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
544404000215	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
544404000216	Walker A/P-loop; other site
544404000217	ATP binding site [chemical binding]; other site
544404000218	Q-loop/lid; other site
544404000219	ABC transporter signature motif; other site
544404000220	Walker B; other site
544404000221	D-loop; other site
544404000222	H-loop/switch region; other site
544404000223	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
544404000224	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404000225	dimer interface [polypeptide binding]; other site
544404000226	conserved gate region; other site
544404000227	putative PBP binding loops; other site
544404000228	ABC-ATPase subunit interface; other site
544404000229	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404000230	dimer interface [polypeptide binding]; other site
544404000231	conserved gate region; other site
544404000232	putative PBP binding loops; other site
544404000233	ABC-ATPase subunit interface; other site
544404000234	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
544404000235	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
544404000236	transcriptional regulator SgrR; Provisional; Region: PRK13626
544404000237	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
544404000238	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
544404000239	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
544404000240	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
544404000241	substrate binding site [chemical binding]; other site
544404000242	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
544404000243	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
544404000244	substrate binding site [chemical binding]; other site
544404000245	ligand binding site [chemical binding]; other site
544404000246	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
544404000247	tartrate dehydrogenase; Region: TTC; TIGR02089
544404000248	2-isopropylmalate synthase; Validated; Region: PRK00915
544404000249	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
544404000250	active site
544404000251	catalytic residues [active]
544404000252	metal binding site [ion binding]; metal-binding site
544404000253	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
544404000254	leu operon leader peptide; Provisional; Region: PRK09925
544404000255	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
544404000256	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404000257	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
544404000258	putative substrate binding pocket [chemical binding]; other site
544404000259	putative dimerization interface [polypeptide binding]; other site
544404000260	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
544404000261	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
544404000262	PYR/PP interface [polypeptide binding]; other site
544404000263	dimer interface [polypeptide binding]; other site
544404000264	TPP binding site [chemical binding]; other site
544404000265	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
544404000266	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
544404000267	TPP-binding site [chemical binding]; other site
544404000268	dimer interface [polypeptide binding]; other site
544404000269	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
544404000270	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
544404000271	putative valine binding site [chemical binding]; other site
544404000272	dimer interface [polypeptide binding]; other site
544404000273	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
544404000274	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
544404000275	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404000276	DNA binding site [nucleotide binding]
544404000277	domain linker motif; other site
544404000278	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
544404000279	dimerization interface [polypeptide binding]; other site
544404000280	ligand binding site [chemical binding]; other site
544404000281	mraZ protein; Region: TIGR00242
544404000282	MraZ protein; Region: MraZ; pfam02381
544404000283	MraZ protein; Region: MraZ; pfam02381
544404000284	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
544404000285	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
544404000286	cell division protein FtsL; Provisional; Region: PRK10772
544404000287	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
544404000288	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
544404000289	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
544404000290	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
544404000291	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
544404000292	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
544404000293	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
544404000294	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
544404000295	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
544404000296	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
544404000297	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
544404000298	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
544404000299	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
544404000300	Mg++ binding site [ion binding]; other site
544404000301	putative catalytic motif [active]
544404000302	putative substrate binding site [chemical binding]; other site
544404000303	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
544404000304	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
544404000305	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
544404000306	cell division protein FtsW; Provisional; Region: PRK10774
544404000307	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
544404000308	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
544404000309	active site
544404000310	homodimer interface [polypeptide binding]; other site
544404000311	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
544404000312	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
544404000313	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
544404000314	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
544404000315	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
544404000316	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
544404000317	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
544404000318	cell division protein FtsQ; Provisional; Region: PRK10775
544404000319	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
544404000320	Cell division protein FtsQ; Region: FtsQ; pfam03799
544404000321	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
544404000322	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404000323	Cell division protein FtsA; Region: FtsA; pfam14450
544404000324	cell division protein FtsZ; Validated; Region: PRK09330
544404000325	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
544404000326	nucleotide binding site [chemical binding]; other site
544404000327	SulA interaction site; other site
544404000328	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
544404000329	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
544404000330	SecA regulator SecM; Provisional; Region: PRK02943
544404000331	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
544404000332	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
544404000333	SEC-C motif; Region: SEC-C; pfam02810
544404000334	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
544404000335	active site
544404000336	8-oxo-dGMP binding site [chemical binding]; other site
544404000337	nudix motif; other site
544404000338	metal binding site [ion binding]; metal-binding site
544404000339	DNA gyrase inhibitor; Reviewed; Region: PRK00418
544404000340	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
544404000341	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
544404000342	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
544404000343	CoA-binding site [chemical binding]; other site
544404000344	ATP-binding [chemical binding]; other site
544404000345	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
544404000346	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
544404000347	active site
544404000348	type IV pilin biogenesis protein; Provisional; Region: PRK10573
544404000349	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
544404000350	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
544404000351	hypothetical protein; Provisional; Region: PRK10436
544404000352	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
544404000353	Walker A motif; other site
544404000354	ATP binding site [chemical binding]; other site
544404000355	Walker B motif; other site
544404000356	putative major pilin subunit; Provisional; Region: PRK10574
544404000357	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
544404000358	Pilin (bacterial filament); Region: Pilin; pfam00114
544404000359	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
544404000360	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
544404000361	dimerization interface [polypeptide binding]; other site
544404000362	active site
544404000363	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
544404000364	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
544404000365	amidase catalytic site [active]
544404000366	Zn binding residues [ion binding]; other site
544404000367	substrate binding site [chemical binding]; other site
544404000368	regulatory protein AmpE; Provisional; Region: PRK10987
544404000369	aromatic amino acid transporter; Provisional; Region: PRK10238
544404000370	Transcriptional regulators [Transcription]; Region: FadR; COG2186
544404000371	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404000372	DNA-binding site [nucleotide binding]; DNA binding site
544404000373	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
544404000374	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
544404000375	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
544404000376	dimer interface [polypeptide binding]; other site
544404000377	TPP-binding site [chemical binding]; other site
544404000378	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
544404000379	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
544404000380	E3 interaction surface; other site
544404000381	lipoyl attachment site [posttranslational modification]; other site
544404000382	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
544404000383	E3 interaction surface; other site
544404000384	lipoyl attachment site [posttranslational modification]; other site
544404000385	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
544404000386	E3 interaction surface; other site
544404000387	lipoyl attachment site [posttranslational modification]; other site
544404000388	e3 binding domain; Region: E3_binding; pfam02817
544404000389	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
544404000390	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
544404000391	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
544404000392	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404000393	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
544404000394	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
544404000395	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
544404000396	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
544404000397	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
544404000398	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
544404000399	substrate binding site [chemical binding]; other site
544404000400	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
544404000401	substrate binding site [chemical binding]; other site
544404000402	ligand binding site [chemical binding]; other site
544404000403	hypothetical protein; Provisional; Region: PRK05248
544404000404	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
544404000405	spermidine synthase; Provisional; Region: PRK00811
544404000406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404000407	S-adenosylmethionine binding site [chemical binding]; other site
544404000408	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
544404000409	multicopper oxidase; Provisional; Region: PRK10965
544404000410	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
544404000411	Multicopper oxidase; Region: Cu-oxidase; pfam00394
544404000412	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
544404000413	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
544404000414	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
544404000415	Trp docking motif [polypeptide binding]; other site
544404000416	putative active site [active]
544404000417	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404000418	active site
544404000419	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
544404000420	active site clefts [active]
544404000421	zinc binding site [ion binding]; other site
544404000422	dimer interface [polypeptide binding]; other site
544404000423	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
544404000424	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
544404000425	Walker A/P-loop; other site
544404000426	ATP binding site [chemical binding]; other site
544404000427	Q-loop/lid; other site
544404000428	ABC transporter signature motif; other site
544404000429	Walker B; other site
544404000430	D-loop; other site
544404000431	H-loop/switch region; other site
544404000432	inner membrane transport permease; Provisional; Region: PRK15066
544404000433	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
544404000434	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
544404000435	active pocket/dimerization site; other site
544404000436	active site
544404000437	phosphorylation site [posttranslational modification]
544404000438	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
544404000439	putative active site [active]
544404000440	putative metal binding site [ion binding]; other site
544404000441	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
544404000442	tetramerization interface [polypeptide binding]; other site
544404000443	active site
544404000444	Uncharacterized conserved protein [Function unknown]; Region: COG5464
544404000445	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
544404000446	pantoate--beta-alanine ligase; Region: panC; TIGR00018
544404000447	Pantoate-beta-alanine ligase; Region: PanC; cd00560
544404000448	active site
544404000449	ATP-binding site [chemical binding]; other site
544404000450	pantoate-binding site; other site
544404000451	HXXH motif; other site
544404000452	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
544404000453	oligomerization interface [polypeptide binding]; other site
544404000454	active site
544404000455	metal binding site [ion binding]; metal-binding site
544404000456	Fimbrial protein; Region: Fimbrial; cl01416
544404000457	putative fimbrial protein StaF; Provisional; Region: PRK15262
544404000458	putative fimbrial protein StaE; Provisional; Region: PRK15263
544404000459	Fimbrial protein; Region: Fimbrial; cl01416
544404000460	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
544404000461	PapC N-terminal domain; Region: PapC_N; pfam13954
544404000462	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404000463	PapC C-terminal domain; Region: PapC_C; pfam13953
544404000464	putative chaperone protein EcpD; Provisional; Region: PRK09926
544404000465	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404000466	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404000467	Fimbrial protein; Region: Fimbrial; cl01416
544404000468	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
544404000469	catalytic center binding site [active]
544404000470	ATP binding site [chemical binding]; other site
544404000471	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
544404000472	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
544404000473	active site
544404000474	NTP binding site [chemical binding]; other site
544404000475	metal binding triad [ion binding]; metal-binding site
544404000476	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
544404000477	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
544404000478	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
544404000479	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
544404000480	active site
544404000481	nucleotide binding site [chemical binding]; other site
544404000482	HIGH motif; other site
544404000483	KMSKS motif; other site
544404000484	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
544404000485	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
544404000486	2'-5' RNA ligase; Provisional; Region: PRK15124
544404000487	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
544404000488	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
544404000489	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
544404000490	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404000491	ATP binding site [chemical binding]; other site
544404000492	putative Mg++ binding site [ion binding]; other site
544404000493	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404000494	nucleotide binding region [chemical binding]; other site
544404000495	ATP-binding site [chemical binding]; other site
544404000496	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
544404000497	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
544404000498	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
544404000499	Transglycosylase; Region: Transgly; pfam00912
544404000500	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
544404000501	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
544404000502	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404000503	N-terminal plug; other site
544404000504	ligand-binding site [chemical binding]; other site
544404000505	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
544404000506	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
544404000507	Walker A/P-loop; other site
544404000508	ATP binding site [chemical binding]; other site
544404000509	Q-loop/lid; other site
544404000510	ABC transporter signature motif; other site
544404000511	Walker B; other site
544404000512	D-loop; other site
544404000513	H-loop/switch region; other site
544404000514	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
544404000515	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
544404000516	siderophore binding site; other site
544404000517	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
544404000518	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404000519	ABC-ATPase subunit  interface; other site
544404000520	dimer interface [polypeptide binding]; other site
544404000521	putative PBP binding regions; other site
544404000522	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404000523	ABC-ATPase subunit  interface; other site
544404000524	dimer interface [polypeptide binding]; other site
544404000525	putative PBP binding regions; other site
544404000526	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
544404000527	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404000528	inhibitor-cofactor binding pocket; inhibition site
544404000529	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404000530	catalytic residue [active]
544404000531	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
544404000532	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
544404000533	Cl- selectivity filter; other site
544404000534	Cl- binding residues [ion binding]; other site
544404000535	pore gating glutamate residue; other site
544404000536	dimer interface [polypeptide binding]; other site
544404000537	H+/Cl- coupling transport residue; other site
544404000538	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
544404000539	hypothetical protein; Provisional; Region: PRK10578
544404000540	UPF0126 domain; Region: UPF0126; pfam03458
544404000541	UPF0126 domain; Region: UPF0126; pfam03458
544404000542	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
544404000543	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
544404000544	cobalamin binding residues [chemical binding]; other site
544404000545	putative BtuC binding residues; other site
544404000546	dimer interface [polypeptide binding]; other site
544404000547	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
544404000548	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
544404000549	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
544404000550	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
544404000551	Zn2+ binding site [ion binding]; other site
544404000552	Mg2+ binding site [ion binding]; other site
544404000553	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
544404000554	serine endoprotease; Provisional; Region: PRK10942
544404000555	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
544404000556	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
544404000557	protein binding site [polypeptide binding]; other site
544404000558	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
544404000559	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
544404000560	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
544404000561	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
544404000562	hypothetical protein; Provisional; Region: PRK13677
544404000563	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
544404000564	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
544404000565	trimer interface [polypeptide binding]; other site
544404000566	active site
544404000567	substrate binding site [chemical binding]; other site
544404000568	CoA binding site [chemical binding]; other site
544404000569	PII uridylyl-transferase; Provisional; Region: PRK05007
544404000570	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
544404000571	metal binding triad; other site
544404000572	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
544404000573	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
544404000574	Zn2+ binding site [ion binding]; other site
544404000575	Mg2+ binding site [ion binding]; other site
544404000576	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
544404000577	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
544404000578	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
544404000579	active site
544404000580	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
544404000581	rRNA interaction site [nucleotide binding]; other site
544404000582	S8 interaction site; other site
544404000583	putative laminin-1 binding site; other site
544404000584	elongation factor Ts; Provisional; Region: tsf; PRK09377
544404000585	UBA/TS-N domain; Region: UBA; pfam00627
544404000586	Elongation factor TS; Region: EF_TS; pfam00889
544404000587	Elongation factor TS; Region: EF_TS; pfam00889
544404000588	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
544404000589	putative nucleotide binding site [chemical binding]; other site
544404000590	uridine monophosphate binding site [chemical binding]; other site
544404000591	homohexameric interface [polypeptide binding]; other site
544404000592	ribosome recycling factor; Reviewed; Region: frr; PRK00083
544404000593	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
544404000594	hinge region; other site
544404000595	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
544404000596	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
544404000597	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
544404000598	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
544404000599	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
544404000600	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
544404000601	catalytic residue [active]
544404000602	putative FPP diphosphate  binding site; other site
544404000603	putative FPP binding hydrophobic cleft; other site
544404000604	dimer interface [polypeptide binding]; other site
544404000605	putative IPP diphosphate binding site; other site
544404000606	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
544404000607	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
544404000608	zinc metallopeptidase RseP; Provisional; Region: PRK10779
544404000609	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
544404000610	active site
544404000611	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
544404000612	protein binding site [polypeptide binding]; other site
544404000613	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
544404000614	putative substrate binding region [chemical binding]; other site
544404000615	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
544404000616	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
544404000617	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
544404000618	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
544404000619	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
544404000620	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
544404000621	Surface antigen; Region: Bac_surface_Ag; pfam01103
544404000622	periplasmic chaperone; Provisional; Region: PRK10780
544404000623	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
544404000624	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
544404000625	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
544404000626	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
544404000627	trimer interface [polypeptide binding]; other site
544404000628	active site
544404000629	UDP-GlcNAc binding site [chemical binding]; other site
544404000630	lipid binding site [chemical binding]; lipid-binding site
544404000631	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
544404000632	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
544404000633	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
544404000634	active site
544404000635	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
544404000636	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
544404000637	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
544404000638	RNA/DNA hybrid binding site [nucleotide binding]; other site
544404000639	active site
544404000640	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
544404000641	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
544404000642	putative active site [active]
544404000643	putative PHP Thumb interface [polypeptide binding]; other site
544404000644	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
544404000645	generic binding surface II; other site
544404000646	generic binding surface I; other site
544404000647	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
544404000648	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
544404000649	lysine decarboxylase LdcC; Provisional; Region: PRK15399
544404000650	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
544404000651	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
544404000652	homodimer interface [polypeptide binding]; other site
544404000653	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404000654	catalytic residue [active]
544404000655	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
544404000656	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
544404000657	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
544404000658	putative metal binding site [ion binding]; other site
544404000659	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
544404000660	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
544404000661	Ligand Binding Site [chemical binding]; other site
544404000662	TilS substrate binding domain; Region: TilS; pfam09179
544404000663	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
544404000664	Rho-binding antiterminator; Provisional; Region: PRK11625
544404000665	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
544404000666	hypothetical protein; Provisional; Region: PRK09256
544404000667	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
544404000668	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
544404000669	NlpE N-terminal domain; Region: NlpE; pfam04170
544404000670	hypothetical protein; Provisional; Region: PRK11479
544404000671	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
544404000672	prolyl-tRNA synthetase; Provisional; Region: PRK09194
544404000673	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
544404000674	dimer interface [polypeptide binding]; other site
544404000675	motif 1; other site
544404000676	active site
544404000677	motif 2; other site
544404000678	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
544404000679	putative deacylase active site [active]
544404000680	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
544404000681	active site
544404000682	motif 3; other site
544404000683	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
544404000684	anticodon binding site; other site
544404000685	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
544404000686	homodimer interaction site [polypeptide binding]; other site
544404000687	cofactor binding site; other site
544404000688	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
544404000689	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
544404000690	lipoprotein, YaeC family; Region: TIGR00363
544404000691	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404000692	dimer interface [polypeptide binding]; other site
544404000693	conserved gate region; other site
544404000694	ABC-ATPase subunit interface; other site
544404000695	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
544404000696	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
544404000697	Walker A/P-loop; other site
544404000698	ATP binding site [chemical binding]; other site
544404000699	Q-loop/lid; other site
544404000700	ABC transporter signature motif; other site
544404000701	Walker B; other site
544404000702	D-loop; other site
544404000703	H-loop/switch region; other site
544404000704	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
544404000705	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
544404000706	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404000707	active site
544404000708	motif I; other site
544404000709	motif II; other site
544404000710	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404000711	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404000712	active site
544404000713	catalytic tetrad [active]
544404000714	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404000715	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404000716	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
544404000717	putative effector binding pocket; other site
544404000718	dimerization interface [polypeptide binding]; other site
544404000719	hypothetical protein; Provisional; Region: PRK05421
544404000720	putative catalytic site [active]
544404000721	putative metal binding site [ion binding]; other site
544404000722	putative phosphate binding site [ion binding]; other site
544404000723	putative catalytic site [active]
544404000724	putative phosphate binding site [ion binding]; other site
544404000725	putative metal binding site [ion binding]; other site
544404000726	Methyltransferase domain; Region: Methyltransf_31; pfam13847
544404000727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404000728	S-adenosylmethionine binding site [chemical binding]; other site
544404000729	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
544404000730	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404000731	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404000732	catalytic residue [active]
544404000733	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404000734	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404000735	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
544404000736	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404000737	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
544404000738	RNA/DNA hybrid binding site [nucleotide binding]; other site
544404000739	active site
544404000740	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
544404000741	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
544404000742	active site
544404000743	catalytic site [active]
544404000744	substrate binding site [chemical binding]; other site
544404000745	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
544404000746	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
544404000747	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
544404000748	ImpA domain protein; Region: DUF3702; pfam12486
544404000749	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
544404000750	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
544404000751	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
544404000752	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
544404000753	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
544404000754	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
544404000755	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
544404000756	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
544404000757	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404000758	Walker A motif; other site
544404000759	ATP binding site [chemical binding]; other site
544404000760	Walker B motif; other site
544404000761	arginine finger; other site
544404000762	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404000763	Walker A motif; other site
544404000764	ATP binding site [chemical binding]; other site
544404000765	Walker B motif; other site
544404000766	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
544404000767	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
544404000768	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
544404000769	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
544404000770	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
544404000771	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
544404000772	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
544404000773	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
544404000774	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
544404000775	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
544404000776	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
544404000777	Protein of unknown function (DUF877); Region: DUF877; pfam05943
544404000778	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
544404000779	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
544404000780	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
544404000781	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
544404000782	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
544404000783	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
544404000784	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
544404000785	PAAR motif; Region: PAAR_motif; cl15808
544404000786	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404000787	RHS Repeat; Region: RHS_repeat; cl11982
544404000788	RHS Repeat; Region: RHS_repeat; pfam05593
544404000789	RHS Repeat; Region: RHS_repeat; pfam05593
544404000790	RHS Repeat; Region: RHS_repeat; cl11982
544404000791	RHS Repeat; Region: RHS_repeat; cl11982
544404000792	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404000793	RHS Repeat; Region: RHS_repeat; pfam05593
544404000794	RHS Repeat; Region: RHS_repeat; pfam05593
544404000795	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
544404000796	RHS protein; Region: RHS; pfam03527
544404000797	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404000798	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
544404000799	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
544404000800	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
544404000801	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
544404000802	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
544404000803	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404000804	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
544404000805	RHS protein; Region: RHS; pfam03527
544404000806	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404000807	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
544404000808	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
544404000809	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
544404000810	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404000811	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404000812	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404000813	Erythromycin esterase; Region: Erythro_esteras; cl17110
544404000814	RHS protein; Region: RHS; pfam03527
544404000815	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404000816	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
544404000817	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
544404000818	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404000819	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404000820	C-N hydrolase family amidase; Provisional; Region: PRK10438
544404000821	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
544404000822	putative active site [active]
544404000823	catalytic triad [active]
544404000824	dimer interface [polypeptide binding]; other site
544404000825	multimer interface [polypeptide binding]; other site
544404000826	C-lysozyme inhibitor; Provisional; Region: PRK09993
544404000827	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
544404000828	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
544404000829	active site
544404000830	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
544404000831	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
544404000832	dimer interface [polypeptide binding]; other site
544404000833	active site
544404000834	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
544404000835	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
544404000836	putative active site [active]
544404000837	putative dimer interface [polypeptide binding]; other site
544404000838	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
544404000839	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404000840	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
544404000841	RelB antitoxin; Region: RelB; cl01171
544404000842	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404000843	NlpC/P60 family; Region: NLPC_P60; pfam00877
544404000844	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
544404000845	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
544404000846	FHIPEP family; Region: FHIPEP; pfam00771
544404000847	hypothetical protein; Validated; Region: PRK06778
544404000848	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404000849	ligand binding site [chemical binding]; other site
544404000850	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
544404000851	active site
544404000852	DNA polymerase IV; Validated; Region: PRK02406
544404000853	DNA binding site [nucleotide binding]
544404000854	putative antitoxin of the YafO-YafN toxin-antitoxin system; Provisional; Region: PRK09778
544404000855	putative toxin YafO; Provisional; Region: PRK09885
544404000856	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
544404000857	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404000858	Coenzyme A binding pocket [chemical binding]; other site
544404000859	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
544404000860	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
544404000861	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
544404000862	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
544404000863	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
544404000864	metal binding site [ion binding]; metal-binding site
544404000865	dimer interface [polypeptide binding]; other site
544404000866	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404000867	active site
544404000868	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
544404000869	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
544404000870	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
544404000871	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
544404000872	trimer interface [polypeptide binding]; other site
544404000873	eyelet of channel; other site
544404000874	gamma-glutamyl kinase; Provisional; Region: PRK05429
544404000875	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
544404000876	nucleotide binding site [chemical binding]; other site
544404000877	homotetrameric interface [polypeptide binding]; other site
544404000878	putative phosphate binding site [ion binding]; other site
544404000879	putative allosteric binding site; other site
544404000880	PUA domain; Region: PUA; pfam01472
544404000881	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
544404000882	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
544404000883	putative catalytic cysteine [active]
544404000884	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404000885	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
544404000886	Int/Topo IB signature motif; other site
544404000887	putative transposase OrfB; Reviewed; Region: PHA02517
544404000888	HTH-like domain; Region: HTH_21; pfam13276
544404000889	Integrase core domain; Region: rve; pfam00665
544404000890	Integrase core domain; Region: rve_3; pfam13683
544404000891	Transposase; Region: HTH_Tnp_1; cl17663
544404000892	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404000893	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404000894	non-specific DNA binding site [nucleotide binding]; other site
544404000895	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
544404000896	salt bridge; other site
544404000897	sequence-specific DNA binding site [nucleotide binding]; other site
544404000898	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404000899	Catalytic site [active]
544404000900	Cro; Region: Cro; pfam09048
544404000901	Bacteriophage CII protein; Region: Phage_CII; pfam05269
544404000902	Replication protein P; Region: Phage_lambda_P; pfam06992
544404000903	Phage Tail Collar Domain; Region: Collar; pfam07484
544404000904	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404000905	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404000906	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
544404000907	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
544404000908	catalytic residues [active]
544404000909	catalytic nucleophile [active]
544404000910	Presynaptic Site I dimer interface [polypeptide binding]; other site
544404000911	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
544404000912	Synaptic Flat tetramer interface [polypeptide binding]; other site
544404000913	Synaptic Site I dimer interface [polypeptide binding]; other site
544404000914	DNA binding site [nucleotide binding]
544404000915	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
544404000916	DNA-binding interface [nucleotide binding]; DNA binding site
544404000917	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
544404000918	GIY-YIG motif/motif A; other site
544404000919	putative active site [active]
544404000920	putative metal binding site [ion binding]; other site
544404000921	transcriptional regulator YdeO; Provisional; Region: PRK09940
544404000922	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404000923	Integrase core domain; Region: rve; pfam00665
544404000924	Integrase core domain; Region: rve_3; pfam13683
544404000925	putative transposase OrfB; Reviewed; Region: PHA02517
544404000926	HTH-like domain; Region: HTH_21; pfam13276
544404000927	Integrase core domain; Region: rve; pfam00665
544404000928	Integrase core domain; Region: rve_3; pfam13683
544404000929	Transposase; Region: HTH_Tnp_1; cl17663
544404000930	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404000931	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
544404000932	Walker A/P-loop; other site
544404000933	ATP binding site [chemical binding]; other site
544404000934	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
544404000935	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
544404000936	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
544404000937	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
544404000938	Ash protein family; Region: Phage_ASH; pfam10554
544404000939	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
544404000940	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
544404000941	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
544404000942	active site
544404000943	metal binding site [ion binding]; metal-binding site
544404000944	interdomain interaction site; other site
544404000945	D5 N terminal like; Region: D5_N; smart00885
544404000946	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
544404000947	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
544404000948	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404000949	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404000950	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
544404000951	putative effector binding pocket; other site
544404000952	putative dimerization interface [polypeptide binding]; other site
544404000953	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
544404000954	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
544404000955	NAD(P) binding site [chemical binding]; other site
544404000956	active site
544404000957	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404000958	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404000959	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
544404000960	putative effector binding pocket; other site
544404000961	putative dimerization interface [polypeptide binding]; other site
544404000962	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
544404000963	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
544404000964	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404000965	putative substrate translocation pore; other site
544404000966	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
544404000967	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
544404000968	XdhC Rossmann domain; Region: XdhC_C; pfam13478
544404000969	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
544404000970	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
544404000971	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
544404000972	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
544404000973	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
544404000974	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
544404000975	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404000976	catalytic loop [active]
544404000977	iron binding site [ion binding]; other site
544404000978	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
544404000979	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
544404000980	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
544404000981	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404000982	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
544404000983	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404000984	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404000985	DNA binding residues [nucleotide binding]
544404000986	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
544404000987	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
544404000988	Transposase; Region: HTH_Tnp_1; pfam01527
544404000989	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404000990	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404000991	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404000992	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404000993	homodimer interface [polypeptide binding]; other site
544404000994	putative GKAP docking site [polypeptide binding]; other site
544404000995	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404000996	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404000997	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404000998	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404000999	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404001000	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
544404001001	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
544404001002	putative active site [active]
544404001003	putative FMN binding site [chemical binding]; other site
544404001004	putative substrate binding site [chemical binding]; other site
544404001005	putative catalytic residue [active]
544404001006	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
544404001007	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404001008	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404001009	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
544404001010	putative effector binding pocket; other site
544404001011	putative dimerization interface [polypeptide binding]; other site
544404001012	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404001013	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404001014	active site
544404001015	catalytic tetrad [active]
544404001016	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
544404001017	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404001018	Filamin/ABP280 repeat; Region: Filamin; pfam00630
544404001019	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404001020	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404001021	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404001022	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
544404001023	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404001024	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
544404001025	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404001026	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404001027	active site
544404001028	catalytic tetrad [active]
544404001029	Predicted membrane protein [Function unknown]; Region: COG3059
544404001030	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404001031	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
544404001032	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
544404001033	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404001034	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
544404001035	Cupin; Region: Cupin_6; pfam12852
544404001036	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
544404001037	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404001038	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
544404001039	Cysteine-rich domain; Region: CCG; pfam02754
544404001040	Cysteine-rich domain; Region: CCG; pfam02754
544404001041	iron-sulfur cluster-binding protein; Region: TIGR00273
544404001042	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
544404001043	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404001044	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
544404001045	Uncharacterized conserved protein [Function unknown]; Region: COG1556
544404001046	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404001047	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404001048	DNA binding residues [nucleotide binding]
544404001049	dimerization interface [polypeptide binding]; other site
544404001050	choline dehydrogenase; Validated; Region: PRK02106
544404001051	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
544404001052	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
544404001053	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
544404001054	tetrameric interface [polypeptide binding]; other site
544404001055	NAD binding site [chemical binding]; other site
544404001056	catalytic residues [active]
544404001057	transcriptional regulator BetI; Validated; Region: PRK00767
544404001058	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404001059	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
544404001060	choline transport protein BetT; Provisional; Region: PRK09928
544404001061	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
544404001062	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
544404001063	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
544404001064	Autotransporter beta-domain; Region: Autotransporter; pfam03797
544404001065	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404001066	DNA binding residues [nucleotide binding]
544404001067	dimerization interface [polypeptide binding]; other site
544404001068	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404001069	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
544404001070	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
544404001071	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
544404001072	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
544404001073	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
544404001074	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
544404001075	CoA binding domain; Region: CoA_binding; pfam02629
544404001076	CoA-ligase; Region: Ligase_CoA; pfam00549
544404001077	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
544404001078	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
544404001079	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
544404001080	putative substrate binding site [chemical binding]; other site
544404001081	nucleotide binding site [chemical binding]; other site
544404001082	nucleotide binding site [chemical binding]; other site
544404001083	homodimer interface [polypeptide binding]; other site
544404001084	putative deaminase; Validated; Region: PRK06846
544404001085	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
544404001086	active site
544404001087	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
544404001088	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
544404001089	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
544404001090	ligand binding site [chemical binding]; other site
544404001091	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
544404001092	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404001093	Walker A/P-loop; other site
544404001094	ATP binding site [chemical binding]; other site
544404001095	Q-loop/lid; other site
544404001096	ABC transporter signature motif; other site
544404001097	Walker B; other site
544404001098	D-loop; other site
544404001099	H-loop/switch region; other site
544404001100	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404001101	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404001102	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404001103	TM-ABC transporter signature motif; other site
544404001104	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404001105	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404001106	TM-ABC transporter signature motif; other site
544404001107	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
544404001108	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
544404001109	putative NAD(P) binding site [chemical binding]; other site
544404001110	putative substrate binding site [chemical binding]; other site
544404001111	catalytic Zn binding site [ion binding]; other site
544404001112	structural Zn binding site [ion binding]; other site
544404001113	dimer interface [polypeptide binding]; other site
544404001114	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
544404001115	hypothetical protein; Provisional; Region: PRK09929
544404001116	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
544404001117	Propionate catabolism activator; Region: PrpR_N; pfam06506
544404001118	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404001119	Walker A motif; other site
544404001120	ATP binding site [chemical binding]; other site
544404001121	Walker B motif; other site
544404001122	arginine finger; other site
544404001123	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
544404001124	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
544404001125	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
544404001126	tetramer interface [polypeptide binding]; other site
544404001127	active site
544404001128	Mg2+/Mn2+ binding site [ion binding]; other site
544404001129	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
544404001130	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
544404001131	dimer interface [polypeptide binding]; other site
544404001132	active site
544404001133	citrylCoA binding site [chemical binding]; other site
544404001134	oxalacetate/citrate binding site [chemical binding]; other site
544404001135	coenzyme A binding site [chemical binding]; other site
544404001136	catalytic triad [active]
544404001137	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
544404001138	2-methylcitrate dehydratase; Region: prpD; TIGR02330
544404001139	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
544404001140	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
544404001141	acyl-activating enzyme (AAE) consensus motif; other site
544404001142	putative AMP binding site [chemical binding]; other site
544404001143	putative active site [active]
544404001144	putative CoA binding site [chemical binding]; other site
544404001145	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
544404001146	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
544404001147	Na binding site [ion binding]; other site
544404001148	putative substrate binding site [chemical binding]; other site
544404001149	cytosine deaminase; Provisional; Region: PRK09230
544404001150	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
544404001151	active site
544404001152	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
544404001153	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404001154	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
544404001155	dimerization interface [polypeptide binding]; other site
544404001156	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
544404001157	active site clefts [active]
544404001158	zinc binding site [ion binding]; other site
544404001159	dimer interface [polypeptide binding]; other site
544404001160	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
544404001161	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
544404001162	oligomer interface [polypeptide binding]; other site
544404001163	active site
544404001164	putative cyanate transporter; Provisional; Region: cynX; PRK09705
544404001165	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001166	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
544404001167	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
544404001168	active site
544404001169	substrate binding site [chemical binding]; other site
544404001170	trimer interface [polypeptide binding]; other site
544404001171	CoA binding site [chemical binding]; other site
544404001172	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
544404001173	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001174	putative substrate translocation pore; other site
544404001175	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
544404001176	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
544404001177	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
544404001178	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
544404001179	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
544404001180	lac repressor; Reviewed; Region: lacI; PRK09526
544404001181	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404001182	DNA binding site [nucleotide binding]
544404001183	domain linker motif; other site
544404001184	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
544404001185	ligand binding site [chemical binding]; other site
544404001186	dimerization interface (open form) [polypeptide binding]; other site
544404001187	dimerization interface (closed form) [polypeptide binding]; other site
544404001188	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
544404001189	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
544404001190	conserved cys residue [active]
544404001191	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404001192	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
544404001193	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
544404001194	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
544404001195	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
544404001196	Bacterial transcriptional regulator; Region: IclR; pfam01614
544404001197	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
544404001198	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
544404001199	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
544404001200	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
544404001201	putative active site [active]
544404001202	Fe(II) binding site [ion binding]; other site
544404001203	putative dimer interface [polypeptide binding]; other site
544404001204	putative tetramer interface [polypeptide binding]; other site
544404001205	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
544404001206	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
544404001207	nucleophilic elbow; other site
544404001208	catalytic triad; other site
544404001209	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
544404001210	acetaldehyde dehydrogenase; Validated; Region: PRK08300
544404001211	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
544404001212	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
544404001213	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
544404001214	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
544404001215	active site
544404001216	catalytic residues [active]
544404001217	metal binding site [ion binding]; metal-binding site
544404001218	DmpG-like communication domain; Region: DmpG_comm; pfam07836
544404001219	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
544404001220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001221	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001222	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
544404001223	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
544404001224	S-formylglutathione hydrolase; Region: PLN02442
544404001225	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
544404001226	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
544404001227	substrate binding site [chemical binding]; other site
544404001228	catalytic Zn binding site [ion binding]; other site
544404001229	NAD binding site [chemical binding]; other site
544404001230	structural Zn binding site [ion binding]; other site
544404001231	dimer interface [polypeptide binding]; other site
544404001232	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
544404001233	putative metal binding site [ion binding]; other site
544404001234	putative homodimer interface [polypeptide binding]; other site
544404001235	putative homotetramer interface [polypeptide binding]; other site
544404001236	putative homodimer-homodimer interface [polypeptide binding]; other site
544404001237	putative allosteric switch controlling residues; other site
544404001238	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
544404001239	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404001240	Walker A/P-loop; other site
544404001241	ATP binding site [chemical binding]; other site
544404001242	Q-loop/lid; other site
544404001243	ABC transporter signature motif; other site
544404001244	Walker B; other site
544404001245	D-loop; other site
544404001246	H-loop/switch region; other site
544404001247	TOBE domain; Region: TOBE_2; pfam08402
544404001248	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
544404001249	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404001250	dimer interface [polypeptide binding]; other site
544404001251	conserved gate region; other site
544404001252	putative PBP binding loops; other site
544404001253	ABC-ATPase subunit interface; other site
544404001254	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404001255	dimer interface [polypeptide binding]; other site
544404001256	conserved gate region; other site
544404001257	putative PBP binding loops; other site
544404001258	ABC-ATPase subunit interface; other site
544404001259	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
544404001260	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
544404001261	regulatory protein UhpC; Provisional; Region: PRK11663
544404001262	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001263	putative substrate translocation pore; other site
544404001264	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
544404001265	MASE1; Region: MASE1; pfam05231
544404001266	Histidine kinase; Region: HisKA_3; pfam07730
544404001267	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404001268	ATP binding site [chemical binding]; other site
544404001269	Mg2+ binding site [ion binding]; other site
544404001270	G-X-G motif; other site
544404001271	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404001272	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404001273	active site
544404001274	phosphorylation site [posttranslational modification]
544404001275	intermolecular recognition site; other site
544404001276	dimerization interface [polypeptide binding]; other site
544404001277	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404001278	DNA binding residues [nucleotide binding]
544404001279	dimerization interface [polypeptide binding]; other site
544404001280	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
544404001281	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404001282	substrate binding pocket [chemical binding]; other site
544404001283	membrane-bound complex binding site; other site
544404001284	hinge residues; other site
544404001285	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
544404001286	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
544404001287	Walker A/P-loop; other site
544404001288	ATP binding site [chemical binding]; other site
544404001289	Q-loop/lid; other site
544404001290	ABC transporter signature motif; other site
544404001291	Walker B; other site
544404001292	D-loop; other site
544404001293	H-loop/switch region; other site
544404001294	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
544404001295	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404001296	dimer interface [polypeptide binding]; other site
544404001297	conserved gate region; other site
544404001298	putative PBP binding loops; other site
544404001299	ABC-ATPase subunit interface; other site
544404001300	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
544404001301	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
544404001302	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
544404001303	dimer interface [polypeptide binding]; other site
544404001304	active site
544404001305	Schiff base residues; other site
544404001306	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
544404001307	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
544404001308	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
544404001309	microcin B17 transporter; Reviewed; Region: PRK11098
544404001310	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
544404001311	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
544404001312	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
544404001313	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
544404001314	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
544404001315	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
544404001316	anti-RssB factor; Provisional; Region: PRK10244
544404001317	alkaline phosphatase; Provisional; Region: PRK10518
544404001318	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
544404001319	dimer interface [polypeptide binding]; other site
544404001320	active site
544404001321	hypothetical protein; Provisional; Region: PRK11505
544404001322	psiF repeat; Region: PsiF_repeat; pfam07769
544404001323	psiF repeat; Region: PsiF_repeat; pfam07769
544404001324	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
544404001325	MASE2 domain; Region: MASE2; pfam05230
544404001326	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404001327	metal binding site [ion binding]; metal-binding site
544404001328	active site
544404001329	I-site; other site
544404001330	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
544404001331	pyrroline-5-carboxylate reductase; Region: PLN02688
544404001332	hypothetical protein; Validated; Region: PRK00124
544404001333	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
544404001334	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
544404001335	ADP binding site [chemical binding]; other site
544404001336	magnesium binding site [ion binding]; other site
544404001337	putative shikimate binding site; other site
544404001338	hypothetical protein; Provisional; Region: PRK10380
544404001339	hypothetical protein; Provisional; Region: PRK10481
544404001340	hypothetical protein; Provisional; Region: PRK10579
544404001341	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
544404001342	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
544404001343	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
544404001344	fructokinase; Reviewed; Region: PRK09557
544404001345	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404001346	nucleotide binding site [chemical binding]; other site
544404001347	MFS transport protein AraJ; Provisional; Region: PRK10091
544404001348	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001349	putative substrate translocation pore; other site
544404001350	exonuclease subunit SbcC; Provisional; Region: PRK10246
544404001351	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404001352	Walker A/P-loop; other site
544404001353	ATP binding site [chemical binding]; other site
544404001354	Q-loop/lid; other site
544404001355	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404001356	ABC transporter signature motif; other site
544404001357	Walker B; other site
544404001358	D-loop; other site
544404001359	H-loop/switch region; other site
544404001360	exonuclease subunit SbcD; Provisional; Region: PRK10966
544404001361	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
544404001362	active site
544404001363	metal binding site [ion binding]; metal-binding site
544404001364	DNA binding site [nucleotide binding]
544404001365	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
544404001366	transcriptional regulator PhoB; Provisional; Region: PRK10161
544404001367	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404001368	active site
544404001369	phosphorylation site [posttranslational modification]
544404001370	intermolecular recognition site; other site
544404001371	dimerization interface [polypeptide binding]; other site
544404001372	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404001373	DNA binding site [nucleotide binding]
544404001374	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
544404001375	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
544404001376	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404001377	putative active site [active]
544404001378	heme pocket [chemical binding]; other site
544404001379	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404001380	dimer interface [polypeptide binding]; other site
544404001381	phosphorylation site [posttranslational modification]
544404001382	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404001383	ATP binding site [chemical binding]; other site
544404001384	Mg2+ binding site [ion binding]; other site
544404001385	G-X-G motif; other site
544404001386	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
544404001387	putative proline-specific permease; Provisional; Region: proY; PRK10580
544404001388	Spore germination protein; Region: Spore_permease; cl17796
544404001389	maltodextrin glucosidase; Provisional; Region: PRK10785
544404001390	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
544404001391	homodimer interface [polypeptide binding]; other site
544404001392	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
544404001393	active site
544404001394	homodimer interface [polypeptide binding]; other site
544404001395	catalytic site [active]
544404001396	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
544404001397	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
544404001398	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
544404001399	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
544404001400	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
544404001401	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
544404001402	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
544404001403	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
544404001404	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
544404001405	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
544404001406	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
544404001407	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
544404001408	Protein export membrane protein; Region: SecD_SecF; pfam02355
544404001409	Uncharacterized protein family (UPF0156); Region: RHH_2; pfam03693
544404001410	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
544404001411	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
544404001412	active site
544404001413	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
544404001414	hypothetical protein; Provisional; Region: PRK11530
544404001415	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
544404001416	ATP cone domain; Region: ATP-cone; pfam03477
544404001417	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
544404001418	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
544404001419	catalytic motif [active]
544404001420	Zn binding site [ion binding]; other site
544404001421	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
544404001422	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
544404001423	homopentamer interface [polypeptide binding]; other site
544404001424	active site
544404001425	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
544404001426	putative RNA binding site [nucleotide binding]; other site
544404001427	thiamine monophosphate kinase; Provisional; Region: PRK05731
544404001428	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
544404001429	ATP binding site [chemical binding]; other site
544404001430	dimerization interface [polypeptide binding]; other site
544404001431	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
544404001432	tetramer interfaces [polypeptide binding]; other site
544404001433	binuclear metal-binding site [ion binding]; other site
544404001434	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
544404001435	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404001436	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404001437	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404001438	active site
544404001439	catalytic tetrad [active]
544404001440	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
544404001441	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
544404001442	TPP-binding site; other site
544404001443	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
544404001444	PYR/PP interface [polypeptide binding]; other site
544404001445	dimer interface [polypeptide binding]; other site
544404001446	TPP binding site [chemical binding]; other site
544404001447	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
544404001448	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
544404001449	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
544404001450	substrate binding pocket [chemical binding]; other site
544404001451	chain length determination region; other site
544404001452	substrate-Mg2+ binding site; other site
544404001453	catalytic residues [active]
544404001454	aspartate-rich region 1; other site
544404001455	active site lid residues [active]
544404001456	aspartate-rich region 2; other site
544404001457	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
544404001458	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
544404001459	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
544404001460	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
544404001461	Ligand Binding Site [chemical binding]; other site
544404001462	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
544404001463	active site residue [active]
544404001464	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
544404001465	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
544404001466	conserved cys residue [active]
544404001467	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
544404001468	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
544404001469	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
544404001470	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
544404001471	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
544404001472	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001473	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404001474	putative substrate translocation pore; other site
544404001475	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
544404001476	UbiA prenyltransferase family; Region: UbiA; pfam01040
544404001477	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
544404001478	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
544404001479	Subunit I/III interface [polypeptide binding]; other site
544404001480	Subunit III/IV interface [polypeptide binding]; other site
544404001481	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
544404001482	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
544404001483	D-pathway; other site
544404001484	Putative ubiquinol binding site [chemical binding]; other site
544404001485	Low-spin heme (heme b) binding site [chemical binding]; other site
544404001486	Putative water exit pathway; other site
544404001487	Binuclear center (heme o3/CuB) [ion binding]; other site
544404001488	K-pathway; other site
544404001489	Putative proton exit pathway; other site
544404001490	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
544404001491	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
544404001492	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
544404001493	muropeptide transporter; Reviewed; Region: ampG; PRK11902
544404001494	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001495	putative substrate translocation pore; other site
544404001496	hypothetical protein; Provisional; Region: PRK11627
544404001497	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
544404001498	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
544404001499	transcriptional regulator BolA; Provisional; Region: PRK11628
544404001500	trigger factor; Provisional; Region: tig; PRK01490
544404001501	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
544404001502	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
544404001503	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
544404001504	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
544404001505	oligomer interface [polypeptide binding]; other site
544404001506	active site residues [active]
544404001507	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
544404001508	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
544404001509	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404001510	Walker A motif; other site
544404001511	ATP binding site [chemical binding]; other site
544404001512	Walker B motif; other site
544404001513	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
544404001514	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
544404001515	Found in ATP-dependent protease La (LON); Region: LON; smart00464
544404001516	Found in ATP-dependent protease La (LON); Region: LON; smart00464
544404001517	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404001518	Walker A motif; other site
544404001519	ATP binding site [chemical binding]; other site
544404001520	Walker B motif; other site
544404001521	arginine finger; other site
544404001522	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
544404001523	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
544404001524	IHF dimer interface [polypeptide binding]; other site
544404001525	IHF - DNA interface [nucleotide binding]; other site
544404001526	periplasmic folding chaperone; Provisional; Region: PRK10788
544404001527	SurA N-terminal domain; Region: SurA_N_3; cl07813
544404001528	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
544404001529	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
544404001530	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
544404001531	active site
544404001532	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
544404001533	Ligand Binding Site [chemical binding]; other site
544404001534	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
544404001535	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
544404001536	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
544404001537	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
544404001538	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404001539	active site
544404001540	motif I; other site
544404001541	motif II; other site
544404001542	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
544404001543	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404001544	putative DNA binding site [nucleotide binding]; other site
544404001545	putative Zn2+ binding site [ion binding]; other site
544404001546	AsnC family; Region: AsnC_trans_reg; pfam01037
544404001547	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404001548	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
544404001549	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404001550	Walker A/P-loop; other site
544404001551	ATP binding site [chemical binding]; other site
544404001552	Q-loop/lid; other site
544404001553	ABC transporter signature motif; other site
544404001554	Walker B; other site
544404001555	D-loop; other site
544404001556	H-loop/switch region; other site
544404001557	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
544404001558	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404001559	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
544404001560	Walker A/P-loop; other site
544404001561	ATP binding site [chemical binding]; other site
544404001562	Q-loop/lid; other site
544404001563	ABC transporter signature motif; other site
544404001564	Walker B; other site
544404001565	D-loop; other site
544404001566	H-loop/switch region; other site
544404001567	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
544404001568	Nitrogen regulatory protein P-II; Region: P-II; smart00938
544404001569	ammonium transporter; Provisional; Region: PRK10666
544404001570	acyl-CoA thioesterase II; Provisional; Region: PRK10526
544404001571	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
544404001572	active site
544404001573	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
544404001574	catalytic triad [active]
544404001575	dimer interface [polypeptide binding]; other site
544404001576	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
544404001577	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
544404001578	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
544404001579	DNA binding site [nucleotide binding]
544404001580	active site
544404001581	Uncharacterized conserved protein [Function unknown]; Region: COG5507
544404001582	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
544404001583	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
544404001584	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404001585	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
544404001586	maltose O-acetyltransferase; Provisional; Region: PRK10092
544404001587	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
544404001588	active site
544404001589	substrate binding site [chemical binding]; other site
544404001590	trimer interface [polypeptide binding]; other site
544404001591	CoA binding site [chemical binding]; other site
544404001592	gene expression modulator; Provisional; Region: PRK10945
544404001593	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
544404001594	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
544404001595	Protein export membrane protein; Region: SecD_SecF; cl14618
544404001596	Protein export membrane protein; Region: SecD_SecF; cl14618
544404001597	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
544404001598	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404001599	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404001600	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
544404001601	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404001602	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
544404001603	hypothetical protein; Provisional; Region: PRK11281
544404001604	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
544404001605	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
544404001606	Mechanosensitive ion channel; Region: MS_channel; pfam00924
544404001607	hypothetical protein; Provisional; Region: PRK11038
544404001608	primosomal replication protein N''; Provisional; Region: PRK10093
544404001609	hypothetical protein; Provisional; Region: PRK10527
544404001610	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404001611	active site
544404001612	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
544404001613	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404001614	Walker A motif; other site
544404001615	ATP binding site [chemical binding]; other site
544404001616	Walker B motif; other site
544404001617	DNA polymerase III subunit delta'; Validated; Region: PRK08485
544404001618	arginine finger; other site
544404001619	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
544404001620	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
544404001621	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
544404001622	hypothetical protein; Validated; Region: PRK00153
544404001623	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
544404001624	RecR protein; Region: RecR; pfam02132
544404001625	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
544404001626	putative active site [active]
544404001627	putative metal-binding site [ion binding]; other site
544404001628	tetramer interface [polypeptide binding]; other site
544404001629	heat shock protein 90; Provisional; Region: PRK05218
544404001630	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404001631	ATP binding site [chemical binding]; other site
544404001632	Mg2+ binding site [ion binding]; other site
544404001633	G-X-G motif; other site
544404001634	adenylate kinase; Reviewed; Region: adk; PRK00279
544404001635	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
544404001636	AMP-binding site [chemical binding]; other site
544404001637	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
544404001638	ferrochelatase; Region: hemH; TIGR00109
544404001639	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
544404001640	C-terminal domain interface [polypeptide binding]; other site
544404001641	active site
544404001642	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
544404001643	active site
544404001644	N-terminal domain interface [polypeptide binding]; other site
544404001645	acetyl esterase; Provisional; Region: PRK10162
544404001646	inosine/guanosine kinase; Provisional; Region: PRK15074
544404001647	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404001648	putative cation:proton antiport protein; Provisional; Region: PRK10669
544404001649	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
544404001650	TrkA-N domain; Region: TrkA_N; pfam02254
544404001651	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001652	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404001653	putative substrate translocation pore; other site
544404001654	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
544404001655	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
544404001656	active site
544404001657	metal binding site [ion binding]; metal-binding site
544404001658	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
544404001659	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
544404001660	putative deacylase active site [active]
544404001661	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
544404001662	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
544404001663	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404001664	non-specific DNA binding site [nucleotide binding]; other site
544404001665	salt bridge; other site
544404001666	sequence-specific DNA binding site [nucleotide binding]; other site
544404001667	copper exporting ATPase; Provisional; Region: copA; PRK10671
544404001668	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
544404001669	metal-binding site [ion binding]
544404001670	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
544404001671	metal-binding site [ion binding]
544404001672	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
544404001673	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404001674	motif II; other site
544404001675	glutaminase; Reviewed; Region: PRK12356
544404001676	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
544404001677	amino acid transporter; Region: 2A0306; TIGR00909
544404001678	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
544404001679	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001680	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001681	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001682	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001683	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001684	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
544404001685	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001686	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001687	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001688	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001689	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001690	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001691	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001692	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001693	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001694	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001695	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001696	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001697	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001698	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001699	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001700	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001701	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001702	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001703	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001704	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001705	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001706	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
544404001707	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
544404001708	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
544404001709	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
544404001710	putative active site [active]
544404001711	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404001712	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
544404001713	Walker A/P-loop; other site
544404001714	ATP binding site [chemical binding]; other site
544404001715	Q-loop/lid; other site
544404001716	ABC transporter signature motif; other site
544404001717	Walker B; other site
544404001718	D-loop; other site
544404001719	H-loop/switch region; other site
544404001720	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
544404001721	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; cl06734
544404001722	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404001723	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
544404001724	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
544404001725	DNA binding residues [nucleotide binding]
544404001726	dimer interface [polypeptide binding]; other site
544404001727	copper binding site [ion binding]; other site
544404001728	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
544404001729	Protein of unknown function (DUF2968); Region: DUF2968; pfam11180
544404001730	YadA-like C-terminal region; Region: YadA; pfam03895
544404001731	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
544404001732	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
544404001733	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
544404001734	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
544404001735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404001736	Walker A/P-loop; other site
544404001737	ATP binding site [chemical binding]; other site
544404001738	Q-loop/lid; other site
544404001739	ABC transporter signature motif; other site
544404001740	Walker B; other site
544404001741	D-loop; other site
544404001742	H-loop/switch region; other site
544404001743	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
544404001744	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
544404001745	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
544404001746	oxidoreductase; Provisional; Region: PRK08017
544404001747	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
544404001748	NADP binding site [chemical binding]; other site
544404001749	active site
544404001750	steroid binding site; other site
544404001751	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
544404001752	active site
544404001753	catalytic triad [active]
544404001754	oxyanion hole [active]
544404001755	switch loop; other site
544404001756	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
544404001757	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
544404001758	Walker A/P-loop; other site
544404001759	ATP binding site [chemical binding]; other site
544404001760	Q-loop/lid; other site
544404001761	ABC transporter signature motif; other site
544404001762	Walker B; other site
544404001763	D-loop; other site
544404001764	H-loop/switch region; other site
544404001765	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
544404001766	FtsX-like permease family; Region: FtsX; pfam02687
544404001767	FtsX-like permease family; Region: FtsX; pfam02687
544404001768	PAAR motif; Region: PAAR_motif; cl15808
544404001769	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404001770	RHS Repeat; Region: RHS_repeat; pfam05593
544404001771	RHS Repeat; Region: RHS_repeat; pfam05593
544404001772	RHS Repeat; Region: RHS_repeat; cl11982
544404001773	RHS Repeat; Region: RHS_repeat; pfam05593
544404001774	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404001775	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
544404001776	RHS Repeat; Region: RHS_repeat; pfam05593
544404001777	RHS protein; Region: RHS; pfam03527
544404001778	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404001779	hypothetical protein; Provisional; Region: PRK14710
544404001780	Winged helix-turn helix; Region: HTH_29; pfam13551
544404001781	Helix-turn-helix domain; Region: HTH_28; pfam13518
544404001782	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
544404001783	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
544404001784	active site residue [active]
544404001785	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
544404001786	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404001787	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404001788	dimerization interface [polypeptide binding]; other site
544404001789	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
544404001790	ureidoglycolate hydrolase; Provisional; Region: PRK03606
544404001791	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
544404001792	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
544404001793	Bacterial transcriptional regulator; Region: IclR; pfam01614
544404001794	glyoxylate carboligase; Provisional; Region: PRK11269
544404001795	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
544404001796	PYR/PP interface [polypeptide binding]; other site
544404001797	dimer interface [polypeptide binding]; other site
544404001798	TPP binding site [chemical binding]; other site
544404001799	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
544404001800	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
544404001801	TPP-binding site [chemical binding]; other site
544404001802	hydroxypyruvate isomerase; Provisional; Region: PRK09997
544404001803	tartronate semialdehyde reductase; Provisional; Region: PRK15059
544404001804	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
544404001805	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
544404001806	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
544404001807	Na binding site [ion binding]; other site
544404001808	substrate binding site [chemical binding]; other site
544404001809	putative uracil/xanthine transporter; Provisional; Region: PRK11412
544404001810	glycerate kinase II; Provisional; Region: PRK09932
544404001811	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
544404001812	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
544404001813	Cupin domain; Region: Cupin_2; cl17218
544404001814	allantoate amidohydrolase; Region: AllC; TIGR03176
544404001815	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
544404001816	active site
544404001817	metal binding site [ion binding]; metal-binding site
544404001818	dimer interface [polypeptide binding]; other site
544404001819	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
544404001820	membrane protein FdrA; Validated; Region: PRK06091
544404001821	CoA binding domain; Region: CoA_binding; pfam02629
544404001822	CoA-ligase; Region: Ligase_CoA; pfam00549
544404001823	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
544404001824	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
544404001825	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
544404001826	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
544404001827	putative substrate binding site [chemical binding]; other site
544404001828	nucleotide binding site [chemical binding]; other site
544404001829	nucleotide binding site [chemical binding]; other site
544404001830	homodimer interface [polypeptide binding]; other site
544404001831	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
544404001832	ATP-grasp domain; Region: ATP-grasp; pfam02222
544404001833	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
544404001834	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
544404001835	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
544404001836	putative active site [active]
544404001837	putative metal binding site [ion binding]; other site
544404001838	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
544404001839	substrate binding site [chemical binding]; other site
544404001840	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
544404001841	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
544404001842	active site
544404001843	HIGH motif; other site
544404001844	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
544404001845	KMSKS motif; other site
544404001846	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
544404001847	tRNA binding surface [nucleotide binding]; other site
544404001848	anticodon binding site; other site
544404001849	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
544404001850	ribosome-associated protein; Provisional; Region: PRK11507
544404001851	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
544404001852	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
544404001853	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
544404001854	homodimer interface [polypeptide binding]; other site
544404001855	NADP binding site [chemical binding]; other site
544404001856	substrate binding site [chemical binding]; other site
544404001857	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
544404001858	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
544404001859	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404001860	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404001861	outer membrane usher protein FimD; Provisional; Region: PRK15198
544404001862	PapC N-terminal domain; Region: PapC_N; pfam13954
544404001863	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404001864	PapC C-terminal domain; Region: PapC_C; pfam13953
544404001865	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
544404001866	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
544404001867	transcriptional regulator FimZ; Provisional; Region: PRK09935
544404001868	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404001869	active site
544404001870	phosphorylation site [posttranslational modification]
544404001871	intermolecular recognition site; other site
544404001872	dimerization interface [polypeptide binding]; other site
544404001873	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404001874	DNA binding residues [nucleotide binding]
544404001875	dimerization interface [polypeptide binding]; other site
544404001876	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
544404001877	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404001878	hypothetical protein; Provisional; Region: PRK09936
544404001879	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
544404001880	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404001881	TPR motif; other site
544404001882	binding surface
544404001883	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
544404001884	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
544404001885	active site
544404001886	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
544404001887	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
544404001888	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
544404001889	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
544404001890	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404001891	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404001892	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404001893	RHS Repeat; Region: RHS_repeat; cl11982
544404001894	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404001895	PAAR motif; Region: PAAR_motif; pfam05488
544404001896	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
544404001897	RHS Repeat; Region: RHS_repeat; pfam05593
544404001898	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
544404001899	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404001900	RHS Repeat; Region: RHS_repeat; cl11982
544404001901	RHS Repeat; Region: RHS_repeat; pfam05593
544404001902	RHS Repeat; Region: RHS_repeat; cl11982
544404001903	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
544404001904	RHS Repeat; Region: RHS_repeat; cl11982
544404001905	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404001906	Uncharacterized conserved protein [Function unknown]; Region: COG5435
544404001907	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
544404001908	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
544404001909	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
544404001910	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
544404001911	sensor kinase CusS; Provisional; Region: PRK09835
544404001912	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404001913	dimerization interface [polypeptide binding]; other site
544404001914	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404001915	dimer interface [polypeptide binding]; other site
544404001916	phosphorylation site [posttranslational modification]
544404001917	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404001918	ATP binding site [chemical binding]; other site
544404001919	Mg2+ binding site [ion binding]; other site
544404001920	G-X-G motif; other site
544404001921	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
544404001922	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404001923	active site
544404001924	phosphorylation site [posttranslational modification]
544404001925	intermolecular recognition site; other site
544404001926	dimerization interface [polypeptide binding]; other site
544404001927	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404001928	DNA binding site [nucleotide binding]
544404001929	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
544404001930	periplasmic copper-binding protein; Provisional; Region: PRK09838
544404001931	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
544404001932	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404001933	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
544404001934	phenylalanine transporter; Provisional; Region: PRK10249
544404001935	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
544404001936	Mechanosensitive ion channel; Region: MS_channel; pfam00924
544404001937	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
544404001938	dimer interface [polypeptide binding]; other site
544404001939	FMN binding site [chemical binding]; other site
544404001940	hypothetical protein; Provisional; Region: PRK10250
544404001941	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
544404001942	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
544404001943	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
544404001944	Hok/gef family; Region: HOK_GEF; pfam01848
544404001945	Hok/gef family; Region: HOK_GEF; pfam01848
544404001946	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
544404001947	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
544404001948	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
544404001949	outer membrane receptor FepA; Provisional; Region: PRK13524
544404001950	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404001951	N-terminal plug; other site
544404001952	ligand-binding site [chemical binding]; other site
544404001953	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
544404001954	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
544404001955	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
544404001956	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
544404001957	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
544404001958	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
544404001959	acyl-activating enzyme (AAE) consensus motif; other site
544404001960	AMP binding site [chemical binding]; other site
544404001961	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
544404001962	LPS O-antigen length regulator; Provisional; Region: PRK10381
544404001963	Chain length determinant protein; Region: Wzz; pfam02706
544404001964	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
544404001965	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
544404001966	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
544404001967	Walker A/P-loop; other site
544404001968	ATP binding site [chemical binding]; other site
544404001969	Q-loop/lid; other site
544404001970	ABC transporter signature motif; other site
544404001971	Walker B; other site
544404001972	D-loop; other site
544404001973	H-loop/switch region; other site
544404001974	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
544404001975	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404001976	ABC-ATPase subunit  interface; other site
544404001977	dimer interface [polypeptide binding]; other site
544404001978	putative PBP binding regions; other site
544404001979	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
544404001980	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404001981	ABC-ATPase subunit  interface; other site
544404001982	dimer interface [polypeptide binding]; other site
544404001983	putative PBP binding regions; other site
544404001984	enterobactin exporter EntS; Provisional; Region: PRK10489
544404001985	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404001986	putative substrate translocation pore; other site
544404001987	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
544404001988	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
544404001989	siderophore binding site; other site
544404001990	isochorismate synthase EntC; Provisional; Region: PRK15016
544404001991	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
544404001992	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
544404001993	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
544404001994	acyl-activating enzyme (AAE) consensus motif; other site
544404001995	active site
544404001996	AMP binding site [chemical binding]; other site
544404001997	substrate binding site [chemical binding]; other site
544404001998	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
544404001999	hydrophobic substrate binding pocket; other site
544404002000	Isochorismatase family; Region: Isochorismatase; pfam00857
544404002001	active site
544404002002	conserved cis-peptide bond; other site
544404002003	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
544404002004	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
544404002005	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
544404002006	putative NAD(P) binding site [chemical binding]; other site
544404002007	active site
544404002008	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
544404002009	CoenzymeA binding site [chemical binding]; other site
544404002010	subunit interaction site [polypeptide binding]; other site
544404002011	PHB binding site; other site
544404002012	carbon starvation protein A; Provisional; Region: PRK15015
544404002013	Carbon starvation protein CstA; Region: CstA; pfam02554
544404002014	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
544404002015	Uncharacterized small protein [Function unknown]; Region: COG2879
544404002016	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
544404002017	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
544404002018	putative active site [active]
544404002019	metal binding site [ion binding]; metal-binding site
544404002020	methionine aminotransferase; Validated; Region: PRK09082
544404002021	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404002022	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404002023	homodimer interface [polypeptide binding]; other site
544404002024	catalytic residue [active]
544404002025	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
544404002026	ParB-like nuclease domain; Region: ParBc; pfam02195
544404002027	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
544404002028	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
544404002029	Active Sites [active]
544404002030	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
544404002031	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
544404002032	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404002033	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404002034	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
544404002035	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
544404002036	dimerization domain [polypeptide binding]; other site
544404002037	dimer interface [polypeptide binding]; other site
544404002038	catalytic residues [active]
544404002039	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
544404002040	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
544404002041	dimer interface [polypeptide binding]; other site
544404002042	decamer (pentamer of dimers) interface [polypeptide binding]; other site
544404002043	catalytic triad [active]
544404002044	peroxidatic and resolving cysteines [active]
544404002045	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
544404002046	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
544404002047	catalytic residue [active]
544404002048	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
544404002049	catalytic residues [active]
544404002050	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404002051	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404002052	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404002053	Ligand Binding Site [chemical binding]; other site
544404002054	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
544404002055	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404002056	NAD binding site [chemical binding]; other site
544404002057	catalytic Zn binding site [ion binding]; other site
544404002058	structural Zn binding site [ion binding]; other site
544404002059	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
544404002060	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
544404002061	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
544404002062	B1 nucleotide binding pocket [chemical binding]; other site
544404002063	B2 nucleotide binding pocket [chemical binding]; other site
544404002064	CAS motifs; other site
544404002065	active site
544404002066	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
544404002067	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
544404002068	transmembrane helices; other site
544404002069	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
544404002070	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
544404002071	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
544404002072	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
544404002073	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
544404002074	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
544404002075	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
544404002076	putative active site [active]
544404002077	(T/H)XGH motif; other site
544404002078	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
544404002079	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404002080	putative active site [active]
544404002081	heme pocket [chemical binding]; other site
544404002082	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404002083	ATP binding site [chemical binding]; other site
544404002084	Mg2+ binding site [ion binding]; other site
544404002085	G-X-G motif; other site
544404002086	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
544404002087	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404002088	active site
544404002089	phosphorylation site [posttranslational modification]
544404002090	intermolecular recognition site; other site
544404002091	dimerization interface [polypeptide binding]; other site
544404002092	Transcriptional regulator; Region: CitT; pfam12431
544404002093	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
544404002094	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
544404002095	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
544404002096	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
544404002097	DNA-binding site [nucleotide binding]; DNA binding site
544404002098	RNA-binding motif; other site
544404002099	chromosome condensation membrane protein; Provisional; Region: PRK14196
544404002100	Predicted amidohydrolase [General function prediction only]; Region: COG0388
544404002101	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
544404002102	putative active site [active]
544404002103	catalytic triad [active]
544404002104	putative dimer interface [polypeptide binding]; other site
544404002105	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
544404002106	lipoyl synthase; Provisional; Region: PRK05481
544404002107	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404002108	FeS/SAM binding site; other site
544404002109	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
544404002110	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404002111	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
544404002112	substrate binding pocket [chemical binding]; other site
544404002113	dimerization interface [polypeptide binding]; other site
544404002114	lipoate-protein ligase B; Provisional; Region: PRK14342
544404002115	hypothetical protein; Provisional; Region: PRK04998
544404002116	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
544404002117	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
544404002118	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
544404002119	rare lipoprotein A; Provisional; Region: PRK10672
544404002120	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
544404002121	Sporulation related domain; Region: SPOR; pfam05036
544404002122	cell wall shape-determining protein; Provisional; Region: PRK10794
544404002123	penicillin-binding protein 2; Provisional; Region: PRK10795
544404002124	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
544404002125	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
544404002126	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
544404002127	ribosome-associated protein; Provisional; Region: PRK11538
544404002128	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
544404002129	catalytic core [active]
544404002130	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
544404002131	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
544404002132	active site
544404002133	(T/H)XGH motif; other site
544404002134	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
544404002135	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
544404002136	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
544404002137	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
544404002138	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
544404002139	HIGH motif; other site
544404002140	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
544404002141	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
544404002142	active site
544404002143	KMSKS motif; other site
544404002144	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
544404002145	tRNA binding surface [nucleotide binding]; other site
544404002146	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
544404002147	hypothetical protein; Provisional; Region: PRK11032
544404002148	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
544404002149	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
544404002150	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
544404002151	HSP70 interaction site [polypeptide binding]; other site
544404002152	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
544404002153	Sel1-like repeats; Region: SEL1; smart00671
544404002154	Sel1-like repeats; Region: SEL1; smart00671
544404002155	Sel1-like repeats; Region: SEL1; smart00671
544404002156	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
544404002157	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
544404002158	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
544404002159	nucleotide binding site [chemical binding]; other site
544404002160	putative NEF/HSP70 interaction site [polypeptide binding]; other site
544404002161	SBD interface [polypeptide binding]; other site
544404002162	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
544404002163	active site
544404002164	tetramer interface [polypeptide binding]; other site
544404002165	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
544404002166	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
544404002167	Walker A/P-loop; other site
544404002168	ATP binding site [chemical binding]; other site
544404002169	Q-loop/lid; other site
544404002170	ABC transporter signature motif; other site
544404002171	Walker B; other site
544404002172	D-loop; other site
544404002173	H-loop/switch region; other site
544404002174	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
544404002175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002176	dimer interface [polypeptide binding]; other site
544404002177	conserved gate region; other site
544404002178	putative PBP binding loops; other site
544404002179	ABC-ATPase subunit interface; other site
544404002180	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
544404002181	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002182	dimer interface [polypeptide binding]; other site
544404002183	conserved gate region; other site
544404002184	putative PBP binding loops; other site
544404002185	ABC-ATPase subunit interface; other site
544404002186	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
544404002187	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404002188	substrate binding pocket [chemical binding]; other site
544404002189	membrane-bound complex binding site; other site
544404002190	hinge residues; other site
544404002191	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
544404002192	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
544404002193	putative active site [active]
544404002194	catalytic triad [active]
544404002195	putative dimer interface [polypeptide binding]; other site
544404002196	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
544404002197	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
544404002198	Transporter associated domain; Region: CorC_HlyC; smart01091
544404002199	metal-binding heat shock protein; Provisional; Region: PRK00016
544404002200	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
544404002201	PhoH-like protein; Region: PhoH; pfam02562
544404002202	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
544404002203	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
544404002204	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404002205	FeS/SAM binding site; other site
544404002206	TRAM domain; Region: TRAM; pfam01938
544404002207	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
544404002208	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
544404002209	asparagine synthetase B; Provisional; Region: asnB; PRK09431
544404002210	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
544404002211	active site
544404002212	dimer interface [polypeptide binding]; other site
544404002213	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
544404002214	Ligand Binding Site [chemical binding]; other site
544404002215	Molecular Tunnel; other site
544404002216	UMP phosphatase; Provisional; Region: PRK10444
544404002217	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002218	active site
544404002219	motif I; other site
544404002220	motif II; other site
544404002221	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002222	MarR family; Region: MarR; pfam01047
544404002223	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
544404002224	ROK family; Region: ROK; pfam00480
544404002225	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
544404002226	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
544404002227	active site
544404002228	dimer interface [polypeptide binding]; other site
544404002229	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
544404002230	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
544404002231	active site
544404002232	trimer interface [polypeptide binding]; other site
544404002233	allosteric site; other site
544404002234	active site lid [active]
544404002235	hexamer (dimer of trimers) interface [polypeptide binding]; other site
544404002236	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
544404002237	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
544404002238	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404002239	active site turn [active]
544404002240	phosphorylation site [posttranslational modification]
544404002241	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
544404002242	HPr interaction site; other site
544404002243	glycerol kinase (GK) interaction site [polypeptide binding]; other site
544404002244	active site
544404002245	phosphorylation site [posttranslational modification]
544404002246	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
544404002247	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
544404002248	active site
544404002249	HIGH motif; other site
544404002250	nucleotide binding site [chemical binding]; other site
544404002251	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
544404002252	KMSKS motif; other site
544404002253	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
544404002254	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12903
544404002255	YbfN-like lipoprotein; Region: YbfN; pfam13982
544404002256	ferric uptake regulator; Provisional; Region: fur; PRK09462
544404002257	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
544404002258	metal binding site 2 [ion binding]; metal-binding site
544404002259	putative DNA binding helix; other site
544404002260	metal binding site 1 [ion binding]; metal-binding site
544404002261	dimer interface [polypeptide binding]; other site
544404002262	structural Zn2+ binding site [ion binding]; other site
544404002263	flavodoxin FldA; Validated; Region: PRK09267
544404002264	LexA regulated protein; Provisional; Region: PRK11675
544404002265	acyl-CoA esterase; Provisional; Region: PRK10673
544404002266	PGAP1-like protein; Region: PGAP1; pfam07819
544404002267	replication initiation regulator SeqA; Provisional; Region: PRK11187
544404002268	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
544404002269	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
544404002270	active site
544404002271	substrate binding site [chemical binding]; other site
544404002272	metal binding site [ion binding]; metal-binding site
544404002273	putrescine transporter; Provisional; Region: potE; PRK10655
544404002274	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
544404002275	ornithine decarboxylase; Provisional; Region: PRK13578
544404002276	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
544404002277	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
544404002278	homodimer interface [polypeptide binding]; other site
544404002279	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404002280	catalytic residue [active]
544404002281	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
544404002282	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
544404002283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404002284	active site
544404002285	phosphorylation site [posttranslational modification]
544404002286	intermolecular recognition site; other site
544404002287	dimerization interface [polypeptide binding]; other site
544404002288	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404002289	DNA binding site [nucleotide binding]
544404002290	sensor protein KdpD; Provisional; Region: PRK10490
544404002291	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
544404002292	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
544404002293	Ligand Binding Site [chemical binding]; other site
544404002294	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
544404002295	GAF domain; Region: GAF_3; pfam13492
544404002296	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404002297	dimer interface [polypeptide binding]; other site
544404002298	phosphorylation site [posttranslational modification]
544404002299	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404002300	ATP binding site [chemical binding]; other site
544404002301	Mg2+ binding site [ion binding]; other site
544404002302	G-X-G motif; other site
544404002303	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
544404002304	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
544404002305	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
544404002306	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
544404002307	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
544404002308	PAAR motif; Region: PAAR_motif; cl15808
544404002309	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404002310	RHS Repeat; Region: RHS_repeat; pfam05593
544404002311	RHS Repeat; Region: RHS_repeat; pfam05593
544404002312	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404002313	RHS Repeat; Region: RHS_repeat; pfam05593
544404002314	RHS Repeat; Region: RHS_repeat; pfam05593
544404002315	RHS protein; Region: RHS; pfam03527
544404002316	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404002317	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
544404002318	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
544404002319	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404002320	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404002321	hypothetical protein; Provisional; Region: PRK10167
544404002322	Uncharacterized conserved protein [Function unknown]; Region: COG3272
544404002323	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
544404002324	DNA photolyase; Region: DNA_photolyase; pfam00875
544404002325	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
544404002326	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404002327	putative substrate translocation pore; other site
544404002328	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404002329	Uncharacterized conserved protein [Function unknown]; Region: COG0327
544404002330	metal-binding protein; Provisional; Region: PRK10799
544404002331	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
544404002332	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
544404002333	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
544404002334	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
544404002335	putative active site [active]
544404002336	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
544404002337	DNA binding site [nucleotide binding]
544404002338	catalytic residue [active]
544404002339	putative catalytic residues [active]
544404002340	H2TH interface [polypeptide binding]; other site
544404002341	intercalation triad [nucleotide binding]; other site
544404002342	substrate specificity determining residue; other site
544404002343	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
544404002344	Putative ammonia monooxygenase; Region: AmoA; pfam05145
544404002345	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
544404002346	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
544404002347	Fimbrial protein; Region: Fimbrial; pfam00419
544404002348	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
544404002349	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404002350	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404002351	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
544404002352	PapC N-terminal domain; Region: PapC_N; pfam13954
544404002353	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404002354	PapC C-terminal domain; Region: PapC_C; pfam13953
544404002355	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404002356	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
544404002357	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
544404002358	dimer interface [polypeptide binding]; other site
544404002359	active site
544404002360	citrylCoA binding site [chemical binding]; other site
544404002361	NADH binding [chemical binding]; other site
544404002362	cationic pore residues; other site
544404002363	oxalacetate/citrate binding site [chemical binding]; other site
544404002364	coenzyme A binding site [chemical binding]; other site
544404002365	catalytic triad [active]
544404002366	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
544404002367	Iron-sulfur protein interface; other site
544404002368	proximal quinone binding site [chemical binding]; other site
544404002369	SdhD (CybS) interface [polypeptide binding]; other site
544404002370	proximal heme binding site [chemical binding]; other site
544404002371	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
544404002372	SdhC subunit interface [polypeptide binding]; other site
544404002373	proximal heme binding site [chemical binding]; other site
544404002374	cardiolipin binding site; other site
544404002375	Iron-sulfur protein interface; other site
544404002376	proximal quinone binding site [chemical binding]; other site
544404002377	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
544404002378	L-aspartate oxidase; Provisional; Region: PRK06175
544404002379	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
544404002380	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
544404002381	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
544404002382	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
544404002383	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
544404002384	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
544404002385	TPP-binding site [chemical binding]; other site
544404002386	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
544404002387	dimer interface [polypeptide binding]; other site
544404002388	PYR/PP interface [polypeptide binding]; other site
544404002389	TPP binding site [chemical binding]; other site
544404002390	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
544404002391	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
544404002392	E3 interaction surface; other site
544404002393	lipoyl attachment site [posttranslational modification]; other site
544404002394	e3 binding domain; Region: E3_binding; pfam02817
544404002395	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
544404002396	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
544404002397	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
544404002398	CoA-ligase; Region: Ligase_CoA; pfam00549
544404002399	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
544404002400	CoA binding domain; Region: CoA_binding; smart00881
544404002401	CoA-ligase; Region: Ligase_CoA; pfam00549
544404002402	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
544404002403	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404002404	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
544404002405	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404002406	dimerization interface [polypeptide binding]; other site
544404002407	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
544404002408	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
544404002409	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
544404002410	homodimer interface [polypeptide binding]; other site
544404002411	Walker A motif; other site
544404002412	ATP binding site [chemical binding]; other site
544404002413	hydroxycobalamin binding site [chemical binding]; other site
544404002414	Walker B motif; other site
544404002415	putative fumarate hydratase; Provisional; Region: PRK15392
544404002416	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
544404002417	Fumarase C-terminus; Region: Fumerase_C; pfam05683
544404002418	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
544404002419	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
544404002420	Domain of unknown function (DUF4387); Region: DUF4387; pfam14330
544404002421	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
544404002422	Methylaspartate ammonia-lyase [Amino acid transport and metabolism]; Region: Mal; COG3799
544404002423	Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the...; Region: MAL; cd03314
544404002424	dimer interface [polypeptide binding]; other site
544404002425	active site
544404002426	Coenzyme B12-dependent glutamate mutase epsilon subunit-like family; contains proteins similar to Clostridium cochlearium glutamate mutase (Glm) and Streptomyces tendae Tu901 NikV. Glm catalyzes a carbon-skeleton rearrangement of L-glutamate to...; Region: Glm_e; cd00245
544404002427	substrate binding site [chemical binding]; other site
544404002428	B12 cofactor binding site [chemical binding]; other site
544404002429	heterodimer (sigma-epsilon) interface [polypeptide binding]; other site
544404002430	homodimer (epsilon-epsilon) interface [polypeptide binding]; other site
544404002431	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
544404002432	conserved hypothetical protein; Region: glmL_fam; TIGR01319
544404002433	nucleotide binding site [chemical binding]; other site
544404002434	B12 binding domain of glutamate mutase (Glm). Glutamate mutase catalysis the conversion of (S)-glutamate with (2S,3S)-3-methylaspartate. The rearrangement reaction is initiated by the extraction of a hydrogen from the protein-bound substrate by a 5'...; Region: Glm_B12_BD; cd02072
544404002435	B12 binding site [chemical binding]; other site
544404002436	heterodimer interface [polypeptide binding]; other site
544404002437	cobalt ligand [ion binding]; other site
544404002438	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
544404002439	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
544404002440	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
544404002441	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
544404002442	hypothetical protein; Provisional; Region: PRK10588
544404002443	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
544404002444	active site
544404002445	colicin uptake protein TolQ; Provisional; Region: PRK10801
544404002446	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
544404002447	colicin uptake protein TolR; Provisional; Region: PRK11024
544404002448	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
544404002449	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
544404002450	TolA C-terminal; Region: TolA; pfam06519
544404002451	translocation protein TolB; Provisional; Region: tolB; PRK03629
544404002452	TolB amino-terminal domain; Region: TolB_N; pfam04052
544404002453	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
544404002454	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
544404002455	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
544404002456	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
544404002457	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404002458	ligand binding site [chemical binding]; other site
544404002459	tol-pal system protein YbgF; Provisional; Region: PRK10803
544404002460	Tetratricopeptide repeat; Region: TPR_6; pfam13174
544404002461	Tetratricopeptide repeat; Region: TPR_6; pfam13174
544404002462	quinolinate synthetase; Provisional; Region: PRK09375
544404002463	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
544404002464	zinc transporter ZitB; Provisional; Region: PRK03557
544404002465	YbgS-like protein; Region: YbgS; pfam13985
544404002466	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
544404002467	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
544404002468	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
544404002469	catalytic core [active]
544404002470	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
544404002471	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
544404002472	active site
544404002473	catalytic residues [active]
544404002474	galactokinase; Provisional; Region: PRK05101
544404002475	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
544404002476	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
544404002477	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
544404002478	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
544404002479	dimer interface [polypeptide binding]; other site
544404002480	active site
544404002481	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
544404002482	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
544404002483	NAD binding site [chemical binding]; other site
544404002484	homodimer interface [polypeptide binding]; other site
544404002485	active site
544404002486	substrate binding site [chemical binding]; other site
544404002487	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
544404002488	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
544404002489	Walker A/P-loop; other site
544404002490	ATP binding site [chemical binding]; other site
544404002491	Q-loop/lid; other site
544404002492	ABC transporter signature motif; other site
544404002493	Walker B; other site
544404002494	D-loop; other site
544404002495	H-loop/switch region; other site
544404002496	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404002497	Walker A/P-loop; other site
544404002498	ATP binding site [chemical binding]; other site
544404002499	Q-loop/lid; other site
544404002500	ABC transporter signature motif; other site
544404002501	Walker B; other site
544404002502	D-loop; other site
544404002503	H-loop/switch region; other site
544404002504	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
544404002505	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
544404002506	molybdenum-pterin binding domain; Region: Mop; TIGR00638
544404002507	TOBE domain; Region: TOBE; pfam03459
544404002508	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
544404002509	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
544404002510	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404002511	substrate binding pocket [chemical binding]; other site
544404002512	membrane-bound complex binding site; other site
544404002513	hinge residues; other site
544404002514	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
544404002515	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002516	putative PBP binding loops; other site
544404002517	ABC-ATPase subunit interface; other site
544404002518	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
544404002519	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404002520	Walker A/P-loop; other site
544404002521	ATP binding site [chemical binding]; other site
544404002522	Q-loop/lid; other site
544404002523	ABC transporter signature motif; other site
544404002524	Walker B; other site
544404002525	D-loop; other site
544404002526	H-loop/switch region; other site
544404002527	molybdenum-pterin binding domain; Region: Mop; TIGR00638
544404002528	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
544404002529	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002530	motif II; other site
544404002531	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002532	6-phosphogluconolactonase; Provisional; Region: PRK11028
544404002533	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404002534	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404002535	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
544404002536	putative dimerization interface [polypeptide binding]; other site
544404002537	PrpF protein; Region: PrpF; pfam04303
544404002538	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
544404002539	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
544404002540	transmembrane helices; other site
544404002541	putative hydratase; Provisional; Region: PRK11413
544404002542	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
544404002543	substrate binding site [chemical binding]; other site
544404002544	ligand binding site [chemical binding]; other site
544404002545	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
544404002546	substrate binding site [chemical binding]; other site
544404002547	acyl-CoA thioesterase; Provisional; Region: PRK10531
544404002548	putative pectinesterase; Region: PLN02432; cl01911
544404002549	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404002550	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
544404002551	dimer interface [polypeptide binding]; other site
544404002552	active site
544404002553	Int/Topo IB signature motif; other site
544404002554	Excisionase-like protein; Region: Exc; pfam07825
544404002555	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
544404002556	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
544404002557	RecT family; Region: RecT; cl04285
544404002558	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
544404002559	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
544404002560	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
544404002561	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
544404002562	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
544404002563	similar to hypothetical protein
544404002564	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404002565	catalytic residues [active]
544404002566	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404002567	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
544404002568	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
544404002569	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
544404002570	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404002571	Phage portal protein, lambda family; Region: Phage_portal_2; pfam05136
544404002572	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404002573	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404002574	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
544404002575	Clp protease; Region: CLP_protease; pfam00574
544404002576	oligomer interface [polypeptide binding]; other site
544404002577	active site residues [active]
544404002578	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
544404002579	Uncharacterized conserved protein [Function unknown]; Region: COG5471
544404002580	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
544404002581	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
544404002582	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
544404002583	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404002584	Bacterial Ig-like domain 2; Region: BID_2; smart00635
544404002585	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; cl06106
544404002586	Minor tail protein T; Region: Phage_tail_T; pfam06223
544404002587	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404002588	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404002589	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404002590	Phage-related protein [Function unknown]; Region: COG4718
544404002591	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404002592	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404002593	MPN+ (JAMM) motif; other site
544404002594	Zinc-binding site [ion binding]; other site
544404002595	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404002596	NlpC/P60 family; Region: NLPC_P60; cl17555
544404002597	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404002598	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404002599	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404002600	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404002601	Fibronectin type III protein; Region: DUF3672; pfam12421
544404002602	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
544404002603	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404002604	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
544404002605	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404002606	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404002607	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
544404002608	type III secretion system protein; Provisional; Region: PRK15384; cl14665
544404002609	NFkB-p65-degrading zinc protease; Region: Peptidase_M85; pfam13678
544404002610	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cl17512
544404002611	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
544404002612	substrate binding site [chemical binding]; other site
544404002613	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
544404002614	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404002615	inhibitor-cofactor binding pocket; inhibition site
544404002616	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404002617	catalytic residue [active]
544404002618	biotin synthase; Provisional; Region: PRK15108
544404002619	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404002620	FeS/SAM binding site; other site
544404002621	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
544404002622	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
544404002623	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
544404002624	substrate-cofactor binding pocket; other site
544404002625	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404002626	catalytic residue [active]
544404002627	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
544404002628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404002629	S-adenosylmethionine binding site [chemical binding]; other site
544404002630	AAA domain; Region: AAA_26; pfam13500
544404002631	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
544404002632	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
544404002633	ADP binding site [chemical binding]; other site
544404002634	excinuclease ABC subunit B; Provisional; Region: PRK05298
544404002635	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404002636	ATP binding site [chemical binding]; other site
544404002637	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404002638	nucleotide binding region [chemical binding]; other site
544404002639	ATP-binding site [chemical binding]; other site
544404002640	Ultra-violet resistance protein B; Region: UvrB; pfam12344
544404002641	UvrB/uvrC motif; Region: UVR; pfam02151
544404002642	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
544404002643	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
544404002644	putative substrate binding pocket [chemical binding]; other site
544404002645	dimer interface [polypeptide binding]; other site
544404002646	phosphate binding site [ion binding]; other site
544404002647	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
544404002648	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404002649	FeS/SAM binding site; other site
544404002650	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
544404002651	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
544404002652	MPT binding site; other site
544404002653	trimer interface [polypeptide binding]; other site
544404002654	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
544404002655	trimer interface [polypeptide binding]; other site
544404002656	dimer interface [polypeptide binding]; other site
544404002657	putative active site [active]
544404002658	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
544404002659	MoaE interaction surface [polypeptide binding]; other site
544404002660	MoeB interaction surface [polypeptide binding]; other site
544404002661	thiocarboxylated glycine; other site
544404002662	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
544404002663	MoaE homodimer interface [polypeptide binding]; other site
544404002664	MoaD interaction [polypeptide binding]; other site
544404002665	active site residues [active]
544404002666	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
544404002667	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
544404002668	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
544404002669	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
544404002670	Predicted integral membrane protein [Function unknown]; Region: COG0392
544404002671	cardiolipin synthase 2; Provisional; Region: PRK11263
544404002672	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
544404002673	putative active site [active]
544404002674	catalytic site [active]
544404002675	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
544404002676	putative active site [active]
544404002677	catalytic site [active]
544404002678	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
544404002679	putative catalytic site [active]
544404002680	putative metal binding site [ion binding]; other site
544404002681	putative phosphate binding site [ion binding]; other site
544404002682	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
544404002683	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
544404002684	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
544404002685	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
544404002686	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
544404002687	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
544404002688	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
544404002689	Walker A/P-loop; other site
544404002690	ATP binding site [chemical binding]; other site
544404002691	Q-loop/lid; other site
544404002692	ABC transporter signature motif; other site
544404002693	Walker B; other site
544404002694	D-loop; other site
544404002695	H-loop/switch region; other site
544404002696	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
544404002697	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
544404002698	Walker A/P-loop; other site
544404002699	ATP binding site [chemical binding]; other site
544404002700	Q-loop/lid; other site
544404002701	ABC transporter signature motif; other site
544404002702	Walker B; other site
544404002703	D-loop; other site
544404002704	H-loop/switch region; other site
544404002705	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
544404002706	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404002707	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404002708	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
544404002709	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
544404002710	helicase 45; Provisional; Region: PTZ00424
544404002711	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
544404002712	ATP binding site [chemical binding]; other site
544404002713	Mg++ binding site [ion binding]; other site
544404002714	motif III; other site
544404002715	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404002716	nucleotide binding region [chemical binding]; other site
544404002717	ATP-binding site [chemical binding]; other site
544404002718	SopA-like central domain; Region: SopA; pfam13981
544404002719	SopA-like catalytic domain; Region: SopA_C; pfam13979
544404002720	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
544404002721	DEAD_2; Region: DEAD_2; pfam06733
544404002722	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
544404002723	glycosyl transferase family protein; Provisional; Region: PRK08136
544404002724	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
544404002725	putative dehydrogenase; Provisional; Region: PRK10098
544404002726	hypothetical protein; Provisional; Region: PRK10259
544404002727	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
544404002728	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
544404002729	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404002730	N-terminal plug; other site
544404002731	ligand-binding site [chemical binding]; other site
544404002732	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404002733	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
544404002734	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
544404002735	putative mechanosensitive channel protein; Provisional; Region: PRK11465
544404002736	Mechanosensitive ion channel; Region: MS_channel; pfam00924
544404002737	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
544404002738	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
544404002739	Walker A/P-loop; other site
544404002740	ATP binding site [chemical binding]; other site
544404002741	Q-loop/lid; other site
544404002742	ABC transporter signature motif; other site
544404002743	Walker B; other site
544404002744	D-loop; other site
544404002745	H-loop/switch region; other site
544404002746	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
544404002747	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002748	dimer interface [polypeptide binding]; other site
544404002749	conserved gate region; other site
544404002750	putative PBP binding loops; other site
544404002751	ABC-ATPase subunit interface; other site
544404002752	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
544404002753	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404002754	substrate binding pocket [chemical binding]; other site
544404002755	membrane-bound complex binding site; other site
544404002756	hinge residues; other site
544404002757	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
544404002758	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
544404002759	dimerization interface [polypeptide binding]; other site
544404002760	DPS ferroxidase diiron center [ion binding]; other site
544404002761	ion pore; other site
544404002762	threonine and homoserine efflux system; Provisional; Region: PRK10532
544404002763	EamA-like transporter family; Region: EamA; pfam00892
544404002764	outer membrane protein X; Provisional; Region: ompX; PRK09408
544404002765	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
544404002766	Sulfatase; Region: Sulfatase; pfam00884
544404002767	manganese transport regulator MntR; Provisional; Region: PRK11050
544404002768	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
544404002769	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
544404002770	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
544404002771	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
544404002772	transmembrane helices; other site
544404002773	L,D-transpeptidase; Provisional; Region: PRK10260
544404002774	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404002775	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
544404002776	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404002777	Walker A/P-loop; other site
544404002778	ATP binding site [chemical binding]; other site
544404002779	Q-loop/lid; other site
544404002780	ABC transporter signature motif; other site
544404002781	Walker B; other site
544404002782	D-loop; other site
544404002783	H-loop/switch region; other site
544404002784	ABC transporter; Region: ABC_tran_2; pfam12848
544404002785	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
544404002786	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
544404002787	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
544404002788	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002789	active site
544404002790	motif I; other site
544404002791	motif II; other site
544404002792	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002793	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
544404002794	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
544404002795	active site
544404002796	intersubunit interactions; other site
544404002797	catalytic residue [active]
544404002798	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
544404002799	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
544404002800	ATP binding site [chemical binding]; other site
544404002801	substrate interface [chemical binding]; other site
544404002802	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
544404002803	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
544404002804	dimer interface [polypeptide binding]; other site
544404002805	putative functional site; other site
544404002806	putative MPT binding site; other site
544404002807	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
544404002808	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404002809	Walker A/P-loop; other site
544404002810	ATP binding site [chemical binding]; other site
544404002811	Q-loop/lid; other site
544404002812	ABC transporter signature motif; other site
544404002813	Walker B; other site
544404002814	D-loop; other site
544404002815	H-loop/switch region; other site
544404002816	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
544404002817	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404002818	Walker A/P-loop; other site
544404002819	ATP binding site [chemical binding]; other site
544404002820	Q-loop/lid; other site
544404002821	ABC transporter signature motif; other site
544404002822	Walker B; other site
544404002823	D-loop; other site
544404002824	H-loop/switch region; other site
544404002825	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
544404002826	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
544404002827	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
544404002828	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
544404002829	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002830	dimer interface [polypeptide binding]; other site
544404002831	conserved gate region; other site
544404002832	putative PBP binding loops; other site
544404002833	ABC-ATPase subunit interface; other site
544404002834	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
544404002835	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
544404002836	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002837	dimer interface [polypeptide binding]; other site
544404002838	conserved gate region; other site
544404002839	putative PBP binding loops; other site
544404002840	ABC-ATPase subunit interface; other site
544404002841	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404002842	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404002843	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404002844	metal binding site [ion binding]; metal-binding site
544404002845	active site
544404002846	I-site; other site
544404002847	Predicted transcriptional regulator [Transcription]; Region: COG2944
544404002848	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404002849	non-specific DNA binding site [nucleotide binding]; other site
544404002850	salt bridge; other site
544404002851	sequence-specific DNA binding site [nucleotide binding]; other site
544404002852	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
544404002853	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
544404002854	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
544404002855	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404002856	FeS/SAM binding site; other site
544404002857	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
544404002858	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
544404002859	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
544404002860	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
544404002861	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
544404002862	putative C-terminal domain interface [polypeptide binding]; other site
544404002863	putative GSH binding site (G-site) [chemical binding]; other site
544404002864	putative dimer interface [polypeptide binding]; other site
544404002865	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
544404002866	N-terminal domain interface [polypeptide binding]; other site
544404002867	dimer interface [polypeptide binding]; other site
544404002868	substrate binding pocket (H-site) [chemical binding]; other site
544404002869	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
544404002870	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
544404002871	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
544404002872	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
544404002873	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
544404002874	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404002875	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
544404002876	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
544404002877	active site
544404002878	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
544404002879	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404002880	putative substrate translocation pore; other site
544404002881	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
544404002882	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002883	active site
544404002884	motif I; other site
544404002885	motif II; other site
544404002886	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404002887	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
544404002888	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404002889	putative substrate translocation pore; other site
544404002890	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404002891	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
544404002892	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404002893	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
544404002894	putative transporter; Provisional; Region: PRK04972
544404002895	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
544404002896	TrkA-C domain; Region: TrkA_C; pfam02080
544404002897	TrkA-C domain; Region: TrkA_C; pfam02080
544404002898	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
544404002899	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
544404002900	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
544404002901	GSH binding site [chemical binding]; other site
544404002902	catalytic residues [active]
544404002903	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
544404002904	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
544404002905	dimer interface [polypeptide binding]; other site
544404002906	FMN binding site [chemical binding]; other site
544404002907	NADPH bind site [chemical binding]; other site
544404002908	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
544404002909	RimK-like ATP-grasp domain; Region: RimK; pfam08443
544404002910	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
544404002911	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
544404002912	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
544404002913	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
544404002914	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404002915	Walker A/P-loop; other site
544404002916	ATP binding site [chemical binding]; other site
544404002917	Q-loop/lid; other site
544404002918	ABC transporter signature motif; other site
544404002919	Walker B; other site
544404002920	D-loop; other site
544404002921	H-loop/switch region; other site
544404002922	TOBE domain; Region: TOBE_2; pfam08402
544404002923	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
544404002924	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002925	dimer interface [polypeptide binding]; other site
544404002926	conserved gate region; other site
544404002927	putative PBP binding loops; other site
544404002928	ABC-ATPase subunit interface; other site
544404002929	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
544404002930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002931	dimer interface [polypeptide binding]; other site
544404002932	conserved gate region; other site
544404002933	putative PBP binding loops; other site
544404002934	ABC-ATPase subunit interface; other site
544404002935	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
544404002936	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
544404002937	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404002938	S-adenosylmethionine binding site [chemical binding]; other site
544404002939	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
544404002940	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
544404002941	active site
544404002942	P-loop; other site
544404002943	phosphorylation site [posttranslational modification]
544404002944	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
544404002945	Sulfatase; Region: Sulfatase; cl17466
544404002946	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
544404002947	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404002948	substrate binding pocket [chemical binding]; other site
544404002949	membrane-bound complex binding site; other site
544404002950	hinge residues; other site
544404002951	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002952	dimer interface [polypeptide binding]; other site
544404002953	conserved gate region; other site
544404002954	putative PBP binding loops; other site
544404002955	ABC-ATPase subunit interface; other site
544404002956	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
544404002957	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404002958	dimer interface [polypeptide binding]; other site
544404002959	conserved gate region; other site
544404002960	putative PBP binding loops; other site
544404002961	ABC-ATPase subunit interface; other site
544404002962	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
544404002963	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404002964	substrate binding pocket [chemical binding]; other site
544404002965	membrane-bound complex binding site; other site
544404002966	hinge residues; other site
544404002967	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
544404002968	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404002969	Walker A/P-loop; other site
544404002970	ATP binding site [chemical binding]; other site
544404002971	Q-loop/lid; other site
544404002972	ABC transporter signature motif; other site
544404002973	Walker B; other site
544404002974	D-loop; other site
544404002975	H-loop/switch region; other site
544404002976	putative lipoprotein; Provisional; Region: PRK10533
544404002977	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
544404002978	hypothetical protein; Provisional; Region: PRK02877
544404002979	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
544404002980	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
544404002981	amidase catalytic site [active]
544404002982	Zn binding residues [ion binding]; other site
544404002983	substrate binding site [chemical binding]; other site
544404002984	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
544404002985	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
544404002986	NAD(P) binding site [chemical binding]; other site
544404002987	active site
544404002988	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
544404002989	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
544404002990	putative NAD(P) binding site [chemical binding]; other site
544404002991	putative active site [active]
544404002992	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
544404002993	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
544404002994	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
544404002995	tetramer interface [polypeptide binding]; other site
544404002996	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404002997	catalytic residue [active]
544404002998	pyruvate dehydrogenase; Provisional; Region: PRK09124
544404002999	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
544404003000	PYR/PP interface [polypeptide binding]; other site
544404003001	dimer interface [polypeptide binding]; other site
544404003002	tetramer interface [polypeptide binding]; other site
544404003003	TPP binding site [chemical binding]; other site
544404003004	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
544404003005	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
544404003006	TPP-binding site [chemical binding]; other site
544404003007	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
544404003008	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
544404003009	FAD binding pocket [chemical binding]; other site
544404003010	FAD binding motif [chemical binding]; other site
544404003011	phosphate binding motif [ion binding]; other site
544404003012	beta-alpha-beta structure motif; other site
544404003013	NAD binding pocket [chemical binding]; other site
544404003014	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404003015	catalytic loop [active]
544404003016	iron binding site [ion binding]; other site
544404003017	hybrid cluster protein; Provisional; Region: PRK05290
544404003018	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404003019	ACS interaction site; other site
544404003020	CODH interaction site; other site
544404003021	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
544404003022	hybrid metal cluster; other site
544404003023	Predicted membrane protein [Function unknown]; Region: COG2431
544404003024	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
544404003025	amphipathic channel; other site
544404003026	Asn-Pro-Ala signature motifs; other site
544404003027	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
544404003028	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
544404003029	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
544404003030	putative active site [active]
544404003031	putative metal-binding site [ion binding]; other site
544404003032	Protein of unknown function (DUF535); Region: DUF535; pfam04393
544404003033	macrolide transporter subunit MacA; Provisional; Region: PRK11578
544404003034	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404003035	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404003036	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
544404003037	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
544404003038	Walker A/P-loop; other site
544404003039	ATP binding site [chemical binding]; other site
544404003040	Q-loop/lid; other site
544404003041	ABC transporter signature motif; other site
544404003042	Walker B; other site
544404003043	D-loop; other site
544404003044	H-loop/switch region; other site
544404003045	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
544404003046	FtsX-like permease family; Region: FtsX; pfam02687
544404003047	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
544404003048	DNA-binding site [nucleotide binding]; DNA binding site
544404003049	RNA-binding motif; other site
544404003050	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
544404003051	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
544404003052	Clp amino terminal domain; Region: Clp_N; pfam02861
544404003053	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404003054	Walker A motif; other site
544404003055	ATP binding site [chemical binding]; other site
544404003056	Walker B motif; other site
544404003057	arginine finger; other site
544404003058	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404003059	Walker A motif; other site
544404003060	ATP binding site [chemical binding]; other site
544404003061	Walker B motif; other site
544404003062	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
544404003063	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
544404003064	rRNA binding site [nucleotide binding]; other site
544404003065	predicted 30S ribosome binding site; other site
544404003066	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
544404003067	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
544404003068	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404003069	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
544404003070	Walker A/P-loop; other site
544404003071	ATP binding site [chemical binding]; other site
544404003072	Q-loop/lid; other site
544404003073	ABC transporter signature motif; other site
544404003074	Walker B; other site
544404003075	D-loop; other site
544404003076	H-loop/switch region; other site
544404003077	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
544404003078	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404003079	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404003080	Walker A/P-loop; other site
544404003081	ATP binding site [chemical binding]; other site
544404003082	Q-loop/lid; other site
544404003083	ABC transporter signature motif; other site
544404003084	Walker B; other site
544404003085	D-loop; other site
544404003086	H-loop/switch region; other site
544404003087	thioredoxin reductase; Provisional; Region: PRK10262
544404003088	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404003089	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404003090	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
544404003091	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404003092	putative DNA binding site [nucleotide binding]; other site
544404003093	putative Zn2+ binding site [ion binding]; other site
544404003094	AsnC family; Region: AsnC_trans_reg; pfam01037
544404003095	DNA translocase FtsK; Provisional; Region: PRK10263
544404003096	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
544404003097	DNA translocase FtsK; Provisional; Region: PRK10263
544404003098	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
544404003099	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
544404003100	periplasmic chaperone LolA; Region: lolA; TIGR00547
544404003101	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
544404003102	recombination factor protein RarA; Reviewed; Region: PRK13342
544404003103	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404003104	Walker A motif; other site
544404003105	ATP binding site [chemical binding]; other site
544404003106	Walker B motif; other site
544404003107	arginine finger; other site
544404003108	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
544404003109	seryl-tRNA synthetase; Provisional; Region: PRK05431
544404003110	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
544404003111	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
544404003112	dimer interface [polypeptide binding]; other site
544404003113	active site
544404003114	motif 1; other site
544404003115	motif 2; other site
544404003116	motif 3; other site
544404003117	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
544404003118	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
544404003119	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
544404003120	putative [Fe4-S4] binding site [ion binding]; other site
544404003121	putative molybdopterin cofactor binding site [chemical binding]; other site
544404003122	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
544404003123	putative molybdopterin cofactor binding site; other site
544404003124	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
544404003125	4Fe-4S binding domain; Region: Fer4; pfam00037
544404003126	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
544404003127	Isochorismatase family; Region: Isochorismatase; pfam00857
544404003128	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
544404003129	catalytic triad [active]
544404003130	dimer interface [polypeptide binding]; other site
544404003131	conserved cis-peptide bond; other site
544404003132	putative MFS family transporter protein; Provisional; Region: PRK03633
544404003133	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404003134	putative substrate translocation pore; other site
544404003135	Amino acid permease; Region: AA_permease_2; pfam13520
544404003136	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
544404003137	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404003138	FeS/SAM binding site; other site
544404003139	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
544404003140	Pyruvate formate lyase 1; Region: PFL1; cd01678
544404003141	coenzyme A binding site [chemical binding]; other site
544404003142	active site
544404003143	catalytic residues [active]
544404003144	glycine loop; other site
544404003145	formate transporter; Provisional; Region: PRK10805
544404003146	uncharacterized domain; Region: TIGR00702
544404003147	YcaO-like family; Region: YcaO; pfam02624
544404003148	Predicted membrane protein [Function unknown]; Region: COG2323
544404003149	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
544404003150	homodimer interface [polypeptide binding]; other site
544404003151	substrate-cofactor binding pocket; other site
544404003152	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404003153	catalytic residue [active]
544404003154	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
544404003155	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
544404003156	hinge; other site
544404003157	active site
544404003158	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
544404003159	cytidylate kinase; Provisional; Region: cmk; PRK00023
544404003160	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
544404003161	CMP-binding site; other site
544404003162	The sites determining sugar specificity; other site
544404003163	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
544404003164	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
544404003165	RNA binding site [nucleotide binding]; other site
544404003166	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
544404003167	RNA binding site [nucleotide binding]; other site
544404003168	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
544404003169	RNA binding site [nucleotide binding]; other site
544404003170	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
544404003171	RNA binding site [nucleotide binding]; other site
544404003172	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
544404003173	RNA binding site [nucleotide binding]; other site
544404003174	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
544404003175	IHF dimer interface [polypeptide binding]; other site
544404003176	IHF - DNA interface [nucleotide binding]; other site
544404003177	ComEC family competence protein; Provisional; Region: PRK11539
544404003178	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
544404003179	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
544404003180	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
544404003181	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
544404003182	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404003183	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
544404003184	Walker A/P-loop; other site
544404003185	ATP binding site [chemical binding]; other site
544404003186	Q-loop/lid; other site
544404003187	ABC transporter signature motif; other site
544404003188	Walker B; other site
544404003189	D-loop; other site
544404003190	H-loop/switch region; other site
544404003191	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
544404003192	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
544404003193	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
544404003194	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
544404003195	hypothetical protein; Provisional; Region: PRK11827
544404003196	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
544404003197	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
544404003198	Ligand binding site; other site
544404003199	oligomer interface; other site
544404003200	hypothetical protein; Provisional; Region: PRK10593
544404003201	Uncharacterized conserved protein [Function unknown]; Region: COG1434
544404003202	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
544404003203	putative active site [active]
544404003204	Methyltransferase domain; Region: Methyltransf_31; pfam13847
544404003205	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404003206	S-adenosylmethionine binding site [chemical binding]; other site
544404003207	condesin subunit F; Provisional; Region: PRK05260
544404003208	condesin subunit E; Provisional; Region: PRK05256
544404003209	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
544404003210	MukB N-terminal; Region: MukB; pfam04310
544404003211	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
544404003212	murein L,D-transpeptidase; Provisional; Region: PRK10594
544404003213	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
544404003214	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404003215	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404003216	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
544404003217	Peptidase M15; Region: Peptidase_M15_3; cl01194
544404003218	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
544404003219	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
544404003220	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404003221	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404003222	homodimer interface [polypeptide binding]; other site
544404003223	catalytic residue [active]
544404003224	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
544404003225	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
544404003226	trimer interface [polypeptide binding]; other site
544404003227	eyelet of channel; other site
544404003228	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
544404003229	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
544404003230	putative dimer interface [polypeptide binding]; other site
544404003231	putative anticodon binding site; other site
544404003232	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
544404003233	homodimer interface [polypeptide binding]; other site
544404003234	motif 1; other site
544404003235	motif 2; other site
544404003236	active site
544404003237	motif 3; other site
544404003238	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
544404003239	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
544404003240	active site
544404003241	aminopeptidase N; Provisional; Region: pepN; PRK14015
544404003242	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
544404003243	active site
544404003244	Zn binding site [ion binding]; other site
544404003245	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
544404003246	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
544404003247	Walker A/P-loop; other site
544404003248	ATP binding site [chemical binding]; other site
544404003249	Q-loop/lid; other site
544404003250	ABC transporter signature motif; other site
544404003251	Walker B; other site
544404003252	D-loop; other site
544404003253	H-loop/switch region; other site
544404003254	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
544404003255	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404003256	dimer interface [polypeptide binding]; other site
544404003257	conserved gate region; other site
544404003258	putative PBP binding loops; other site
544404003259	ABC-ATPase subunit interface; other site
544404003260	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
544404003261	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
544404003262	active site
544404003263	dimer interface [polypeptide binding]; other site
544404003264	non-prolyl cis peptide bond; other site
544404003265	insertion regions; other site
544404003266	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404003267	substrate binding pocket [chemical binding]; other site
544404003268	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
544404003269	membrane-bound complex binding site; other site
544404003270	hinge residues; other site
544404003271	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
544404003272	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
544404003273	Fimbrial protein; Region: Fimbrial; cl01416
544404003274	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
544404003275	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404003276	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404003277	Fimbrial protein; Region: Fimbrial; cl01416
544404003278	Fimbrial protein; Region: Fimbrial; cl01416
544404003279	Fimbrial protein; Region: Fimbrial; cl01416
544404003280	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404003281	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404003282	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
544404003283	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
544404003284	quinone interaction residues [chemical binding]; other site
544404003285	active site
544404003286	catalytic residues [active]
544404003287	FMN binding site [chemical binding]; other site
544404003288	substrate binding site [chemical binding]; other site
544404003289	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
544404003290	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
544404003291	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
544404003292	MOSC domain; Region: MOSC; pfam03473
544404003293	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404003294	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
544404003295	catalytic loop [active]
544404003296	iron binding site [ion binding]; other site
544404003297	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
544404003298	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
544404003299	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
544404003300	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404003301	S-adenosylmethionine binding site [chemical binding]; other site
544404003302	ABC transporter ATPase component; Reviewed; Region: PRK11147
544404003303	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404003304	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404003305	Walker A/P-loop; other site
544404003306	Walker A/P-loop; other site
544404003307	ATP binding site [chemical binding]; other site
544404003308	ATP binding site [chemical binding]; other site
544404003309	Q-loop/lid; other site
544404003310	Q-loop/lid; other site
544404003311	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
544404003312	ABC transporter signature motif; other site
544404003313	Walker B; other site
544404003314	D-loop; other site
544404003315	ABC transporter; Region: ABC_tran_2; pfam12848
544404003316	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
544404003317	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
544404003318	Paraquat-inducible protein A; Region: PqiA; pfam04403
544404003319	Paraquat-inducible protein A; Region: PqiA; pfam04403
544404003320	paraquat-inducible protein B; Provisional; Region: PRK10807
544404003321	mce related protein; Region: MCE; pfam02470
544404003322	mce related protein; Region: MCE; pfam02470
544404003323	mce related protein; Region: MCE; pfam02470
544404003324	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
544404003325	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
544404003326	Protein of unknown function (DUF330); Region: DUF330; pfam03886
544404003327	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
544404003328	active site 1 [active]
544404003329	dimer interface [polypeptide binding]; other site
544404003330	active site 2 [active]
544404003331	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
544404003332	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
544404003333	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
544404003334	outer membrane protein A; Reviewed; Region: PRK10808
544404003335	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
544404003336	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404003337	ligand binding site [chemical binding]; other site
544404003338	cell division inhibitor SulA; Region: sula; TIGR00623
544404003339	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
544404003340	TfoX C-terminal domain; Region: TfoX_C; pfam04994
544404003341	TIGR01666 family membrane protein; Region: YCCS
544404003342	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
544404003343	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
544404003344	Predicted membrane protein [Function unknown]; Region: COG3304
544404003345	Domain of unknown function (DUF307); Region: DUF307; pfam03733
544404003346	Domain of unknown function (DUF307); Region: DUF307; pfam03733
544404003347	DNA helicase IV; Provisional; Region: helD; PRK11054
544404003348	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
544404003349	Part of AAA domain; Region: AAA_19; pfam13245
544404003350	Family description; Region: UvrD_C_2; pfam13538
544404003351	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
544404003352	active site
544404003353	dimer interfaces [polypeptide binding]; other site
544404003354	catalytic residues [active]
544404003355	hypothetical protein; Provisional; Region: PRK03641
544404003356	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
544404003357	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
544404003358	heat shock protein HspQ; Provisional; Region: PRK14129
544404003359	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
544404003360	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
544404003361	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
544404003362	putative RNA binding site [nucleotide binding]; other site
544404003363	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404003364	S-adenosylmethionine binding site [chemical binding]; other site
544404003365	Acylphosphatase; Region: Acylphosphatase; cl00551
544404003366	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
544404003367	sulfur transfer protein TusE; Provisional; Region: PRK11508
544404003368	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
544404003369	YccA-like proteins; Region: YccA_like; cd10433
544404003370	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
544404003371	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404003372	active site
544404003373	substrate binding site [chemical binding]; other site
544404003374	catalytic site [active]
544404003375	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
544404003376	DicB protein; Region: DicB; pfam05358
544404003377	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
544404003378	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
544404003379	transcriptional repressor DicA; Reviewed; Region: PRK09706
544404003380	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404003381	non-specific DNA binding site [nucleotide binding]; other site
544404003382	salt bridge; other site
544404003383	sequence-specific DNA binding site [nucleotide binding]; other site
544404003384	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404003385	primosomal protein DnaI; Provisional; Region: PRK02854
544404003386	putative replication protein; Provisional; Region: PRK12377
544404003387	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404003388	Walker A motif; other site
544404003389	ATP binding site [chemical binding]; other site
544404003390	Walker B motif; other site
544404003391	arginine finger; other site
544404003392	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404003393	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
544404003394	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
544404003395	Hok/gef family; Region: HOK_GEF; pfam01848
544404003396	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404003397	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
544404003398	CAAX protease self-immunity; Region: Abi; pfam02517
544404003399	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404003400	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404003401	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404003402	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404003403	Transposase; Region: HTH_Tnp_1; cl17663
544404003404	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003405	putative transposase OrfB; Reviewed; Region: PHA02517
544404003406	HTH-like domain; Region: HTH_21; pfam13276
544404003407	Integrase core domain; Region: rve; pfam00665
544404003408	Integrase core domain; Region: rve_3; pfam13683
544404003409	PerC transcriptional activator; Region: PerC; pfam06069
544404003410	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404003411	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404003412	catalytic residues [active]
544404003413	Lysis protein S; Region: Lysis_S; pfam04971
544404003414	Phage DNA packaging protein, Nu1 subunit of terminase [DNA replication, recombination, and repair]; Region: COG4220
544404003415	Transposase; Region: HTH_Tnp_1; pfam01527
544404003416	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003417	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003418	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404003419	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404003420	homodimer interface [polypeptide binding]; other site
544404003421	putative GKAP docking site [polypeptide binding]; other site
544404003422	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404003423	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003424	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404003425	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404003426	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404003427	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404003428	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404003429	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
544404003430	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
544404003431	tandem repeat interface [polypeptide binding]; other site
544404003432	oligomer interface [polypeptide binding]; other site
544404003433	active site residues [active]
544404003434	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
544404003435	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
544404003436	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404003437	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404003438	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
544404003439	Minor tail protein T; Region: Phage_tail_T; cl05636
544404003440	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404003441	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404003442	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404003443	Phage-related protein [Function unknown]; Region: COG4718
544404003444	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404003445	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404003446	MPN+ (JAMM) motif; other site
544404003447	Zinc-binding site [ion binding]; other site
544404003448	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404003449	NlpC/P60 family; Region: NLPC_P60; cl17555
544404003450	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404003451	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
544404003452	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
544404003453	E-class dimer interface [polypeptide binding]; other site
544404003454	P-class dimer interface [polypeptide binding]; other site
544404003455	active site
544404003456	Cu2+ binding site [ion binding]; other site
544404003457	Zn2+ binding site [ion binding]; other site
544404003458	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404003459	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404003460	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
544404003461	Interdomain contacts; other site
544404003462	Cytokine receptor motif; other site
544404003463	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404003464	Fibronectin type III protein; Region: DUF3672; pfam12421
544404003465	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
544404003466	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404003467	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404003468	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404003469	EspF protein repeat; Region: EspF; pfam04806
544404003470	EspF protein repeat; Region: EspF; pfam04806
544404003471	EspF protein repeat; Region: EspF; pfam04806
544404003472	EspF protein repeat; Region: EspF; pfam04806
544404003473	EspF protein repeat; Region: EspF; pfam04806
544404003474	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
544404003475	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
544404003476	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
544404003477	hydrogenase 1 large subunit; Provisional; Region: PRK10170
544404003478	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
544404003479	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
544404003480	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
544404003481	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
544404003482	putative substrate-binding site; other site
544404003483	nickel binding site [ion binding]; other site
544404003484	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
544404003485	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
544404003486	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
544404003487	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
544404003488	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
544404003489	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
544404003490	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
544404003491	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
544404003492	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
544404003493	catalytic core [active]
544404003494	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
544404003495	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
544404003496	Chain length determinant protein; Region: Wzz; pfam02706
544404003497	Chain length determinant protein; Region: Wzz; cl15801
544404003498	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
544404003499	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
544404003500	Nucleotide binding site [chemical binding]; other site
544404003501	Low molecular weight phosphatase family; Region: LMWPc; cd00115
544404003502	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
544404003503	active site
544404003504	polysaccharide export protein Wza; Provisional; Region: PRK15078
544404003505	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
544404003506	SLBB domain; Region: SLBB; pfam10531
544404003507	SLBB domain; Region: SLBB; pfam10531
544404003508	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
544404003509	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
544404003510	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
544404003511	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
544404003512	DNA-binding site [nucleotide binding]; DNA binding site
544404003513	RNA-binding motif; other site
544404003514	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
544404003515	DNA-binding site [nucleotide binding]; DNA binding site
544404003516	RNA-binding motif; other site
544404003517	cold shock gene; Provisional; Region: PRK09891
544404003518	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
544404003519	4Fe-4S binding domain; Region: Fer4_5; pfam12801
544404003520	4Fe-4S binding domain; Region: Fer4_5; pfam12801
544404003521	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404003522	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
544404003523	HAMP domain; Region: HAMP; pfam00672
544404003524	dimerization interface [polypeptide binding]; other site
544404003525	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404003526	dimer interface [polypeptide binding]; other site
544404003527	phosphorylation site [posttranslational modification]
544404003528	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404003529	ATP binding site [chemical binding]; other site
544404003530	Mg2+ binding site [ion binding]; other site
544404003531	G-X-G motif; other site
544404003532	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404003533	active site
544404003534	phosphorylation site [posttranslational modification]
544404003535	intermolecular recognition site; other site
544404003536	dimerization interface [polypeptide binding]; other site
544404003537	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
544404003538	putative binding surface; other site
544404003539	active site
544404003540	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
544404003541	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
544404003542	putative ligand binding site [chemical binding]; other site
544404003543	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
544404003544	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404003545	active site
544404003546	phosphorylation site [posttranslational modification]
544404003547	intermolecular recognition site; other site
544404003548	dimerization interface [polypeptide binding]; other site
544404003549	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404003550	DNA binding site [nucleotide binding]
544404003551	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
544404003552	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
544404003553	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
544404003554	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
544404003555	molybdopterin cofactor binding site [chemical binding]; other site
544404003556	substrate binding site [chemical binding]; other site
544404003557	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
544404003558	molybdopterin cofactor binding site; other site
544404003559	chaperone protein TorD; Validated; Region: torD; PRK04976
544404003560	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
544404003561	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
544404003562	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
544404003563	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
544404003564	HSP70 interaction site [polypeptide binding]; other site
544404003565	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
544404003566	substrate binding site [polypeptide binding]; other site
544404003567	dimer interface [polypeptide binding]; other site
544404003568	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
544404003569	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
544404003570	catalytic core [active]
544404003571	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
544404003572	hypothetical protein; Provisional; Region: PRK10174
544404003573	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
544404003574	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
544404003575	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
544404003576	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
544404003577	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
544404003578	putative FMN binding site [chemical binding]; other site
544404003579	pyrimidine utilization protein D; Region: RutD; TIGR03611
544404003580	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
544404003581	homotrimer interaction site [polypeptide binding]; other site
544404003582	Isochorismatase family; Region: Isochorismatase; pfam00857
544404003583	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
544404003584	catalytic triad [active]
544404003585	conserved cis-peptide bond; other site
544404003586	pyrimidine utilization protein A; Region: RutA; TIGR03612
544404003587	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
544404003588	active site
544404003589	dimer interface [polypeptide binding]; other site
544404003590	non-prolyl cis peptide bond; other site
544404003591	insertion regions; other site
544404003592	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
544404003593	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
544404003594	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404003595	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
544404003596	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
544404003597	Predicted transcriptional regulator [Transcription]; Region: COG3905
544404003598	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
544404003599	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
544404003600	Glutamate binding site [chemical binding]; other site
544404003601	NAD binding site [chemical binding]; other site
544404003602	catalytic residues [active]
544404003603	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
544404003604	Na binding site [ion binding]; other site
544404003605	FTR1 family protein; Region: TIGR00145
544404003606	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
544404003607	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
544404003608	Imelysin; Region: Peptidase_M75; pfam09375
544404003609	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
544404003610	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
544404003611	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
544404003612	hypothetical protein; Provisional; Region: PRK10536
544404003613	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
544404003614	N-glycosyltransferase; Provisional; Region: PRK11204
544404003615	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
544404003616	DXD motif; other site
544404003617	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
544404003618	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
544404003619	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
544404003620	putative active site [active]
544404003621	putative metal binding site [ion binding]; other site
544404003622	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
544404003623	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404003624	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404003625	metal binding site [ion binding]; metal-binding site
544404003626	active site
544404003627	I-site; other site
544404003628	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
544404003629	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404003630	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
544404003631	DNA binding site [nucleotide binding]
544404003632	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
544404003633	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
544404003634	NADP binding site [chemical binding]; other site
544404003635	homodimer interface [polypeptide binding]; other site
544404003636	active site
544404003637	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
544404003638	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404003639	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404003640	Fimbrial protein; Region: Fimbrial; cl01416
544404003641	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
544404003642	PapC N-terminal domain; Region: PapC_N; pfam13954
544404003643	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404003644	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
544404003645	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404003646	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404003647	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404003648	haemagglutination activity domain; Region: Haemagg_act; pfam05860
544404003649	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
544404003650	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
544404003651	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
544404003652	Phosphopantetheinyl transferase (holo-ACP synthase) [Lipid metabolism]; Region: AcpS; COG0736
544404003653	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
544404003654	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
544404003655	NAD(P) binding site [chemical binding]; other site
544404003656	active site
544404003657	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
544404003658	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
544404003659	Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; Region: GcvT; COG0404
544404003660	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
544404003661	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
544404003662	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
544404003663	dimer interface [polypeptide binding]; other site
544404003664	active site
544404003665	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
544404003666	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
544404003667	active site
544404003668	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
544404003669	"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP)...; Region: elong_cond_enzymes; cd00828
544404003670	active site
544404003671	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
544404003672	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
544404003673	Walker A/P-loop; other site
544404003674	ATP binding site [chemical binding]; other site
544404003675	Q-loop/lid; other site
544404003676	ABC transporter signature motif; other site
544404003677	Walker B; other site
544404003678	D-loop; other site
544404003679	H-loop/switch region; other site
544404003680	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
544404003681	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
544404003682	FtsX-like permease family; Region: FtsX; pfam02687
544404003683	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
544404003684	integrase; Provisional; Region: PRK09692
544404003685	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404003686	active site
544404003687	Int/Topo IB signature motif; other site
544404003688	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
544404003689	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
544404003690	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
544404003691	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
544404003692	putative transposase OrfB; Reviewed; Region: PHA02517
544404003693	HTH-like domain; Region: HTH_21; pfam13276
544404003694	Integrase core domain; Region: rve; pfam00665
544404003695	Integrase core domain; Region: rve_3; pfam13683
544404003696	Transposase; Region: HTH_Tnp_1; cl17663
544404003697	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003698	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
544404003699	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
544404003700	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4951
544404003701	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
544404003702	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404003703	ATP binding site [chemical binding]; other site
544404003704	putative Mg++ binding site [ion binding]; other site
544404003705	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404003706	nucleotide binding region [chemical binding]; other site
544404003707	ATP-binding site [chemical binding]; other site
544404003708	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404003709	homodimer interface [polypeptide binding]; other site
544404003710	putative GKAP docking site [polypeptide binding]; other site
544404003711	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404003712	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003713	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404003714	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404003715	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404003716	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003717	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404003718	Transposase; Region: HTH_Tnp_1; pfam01527
544404003719	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003720	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
544404003721	DNA-binding interface [nucleotide binding]; DNA binding site
544404003722	Helix-turn-helix domain; Region: HTH_38; pfam13936
544404003723	putative transposase OrfB; Reviewed; Region: PHA02517
544404003724	Integrase core domain; Region: rve; pfam00665
544404003725	Integrase core domain; Region: rve_3; pfam13683
544404003726	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
544404003727	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
544404003728	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
544404003729	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
544404003730	Sulfatase; Region: Sulfatase; pfam00884
544404003731	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
544404003732	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
544404003733	alpha-gamma subunit interface [polypeptide binding]; other site
544404003734	beta-gamma subunit interface [polypeptide binding]; other site
544404003735	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
544404003736	gamma-beta subunit interface [polypeptide binding]; other site
544404003737	alpha-beta subunit interface [polypeptide binding]; other site
544404003738	urease subunit alpha; Reviewed; Region: ureC; PRK13207
544404003739	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
544404003740	subunit interactions [polypeptide binding]; other site
544404003741	active site
544404003742	flap region; other site
544404003743	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
544404003744	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
544404003745	dimer interface [polypeptide binding]; other site
544404003746	catalytic residues [active]
544404003747	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
544404003748	UreF; Region: UreF; pfam01730
544404003749	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
544404003750	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404003751	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003752	Transposase; Region: HTH_Tnp_1; pfam01527
544404003753	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
544404003754	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
544404003755	Hok/gef family; Region: HOK_GEF; pfam01848
544404003756	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404003757	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003758	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404003759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003760	Transposase; Region: HTH_Tnp_1; pfam01527
544404003761	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003762	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404003763	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404003764	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003765	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404003766	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404003767	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404003768	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404003769	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003770	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404003771	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404003772	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404003773	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404003774	Predicted transcriptional regulator [Transcription]; Region: COG2378
544404003775	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
544404003776	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
544404003777	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
544404003778	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
544404003779	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404003780	active site
544404003781	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
544404003782	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
544404003783	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
544404003784	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
544404003785	putative metal binding site [ion binding]; other site
544404003786	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
544404003787	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
544404003788	putative metal binding site [ion binding]; other site
544404003789	Uncharacterized protein involved in stress response [General function prediction only]; Region: COG4110
544404003790	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
544404003791	putative metal binding site [ion binding]; other site
544404003792	tellurite resistance protein terB; Region: terB; cd07176
544404003793	putative metal binding site [ion binding]; other site
544404003794	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
544404003795	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
544404003796	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
544404003797	putative metal binding site [ion binding]; other site
544404003798	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
544404003799	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
544404003800	putative metal binding site [ion binding]; other site
544404003801	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
544404003802	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
544404003803	putative metal binding site [ion binding]; other site
544404003804	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
544404003805	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404003806	N-terminal plug; other site
544404003807	ligand-binding site [chemical binding]; other site
544404003808	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
544404003809	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
544404003810	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
544404003811	TDP-binding site; other site
544404003812	homodimer interface [polypeptide binding]; other site
544404003813	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
544404003814	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
544404003815	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
544404003816	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
544404003817	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
544404003818	Helix-turn-helix domain; Region: HTH_39; pfam14090
544404003819	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
544404003820	putative transposase OrfB; Reviewed; Region: PHA02517
544404003821	HTH-like domain; Region: HTH_21; pfam13276
544404003822	Integrase core domain; Region: rve; pfam00665
544404003823	Integrase core domain; Region: rve_3; pfam13683
544404003824	Transposase; Region: HTH_Tnp_1; cl17663
544404003825	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003826	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
544404003827	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
544404003828	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
544404003829	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
544404003830	Active Sites [active]
544404003831	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
544404003832	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
544404003833	ParB-like nuclease domain; Region: ParB; smart00470
544404003834	PerC transcriptional activator; Region: PerC; pfam06069
544404003835	Homeodomain-like domain; Region: HTH_32; pfam13565
544404003836	Integrase core domain; Region: rve_3; cl15866
544404003837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404003838	Transposase; Region: HTH_Tnp_1; pfam01527
544404003839	Predicted GTPase [General function prediction only]; Region: COG3596
544404003840	YfjP GTPase; Region: YfjP; cd11383
544404003841	G1 box; other site
544404003842	GTP/Mg2+ binding site [chemical binding]; other site
544404003843	Switch I region; other site
544404003844	G2 box; other site
544404003845	Switch II region; other site
544404003846	G3 box; other site
544404003847	G4 box; other site
544404003848	G5 box; other site
544404003849	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
544404003850	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
544404003851	hypothetical protein; Provisional; Region: PRK09945
544404003852	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
544404003853	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
544404003854	Autotransporter beta-domain; Region: Autotransporter; smart00869
544404003855	hypothetical protein; Provisional; Region: PRK09866
544404003856	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
544404003857	G1 box; other site
544404003858	GTP/Mg2+ binding site [chemical binding]; other site
544404003859	G2 box; other site
544404003860	Switch I region; other site
544404003861	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
544404003862	G3 box; other site
544404003863	Switch II region; other site
544404003864	GTP/Mg2+ binding site [chemical binding]; other site
544404003865	G4 box; other site
544404003866	G5 box; other site
544404003867	YjcZ-like protein; Region: YjcZ; pfam13990
544404003868	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
544404003869	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
544404003870	nucleophile elbow; other site
544404003871	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
544404003872	Domain of unknown function (DUF932); Region: DUF932; pfam06067
544404003873	Antirestriction protein; Region: Antirestrict; pfam03230
544404003874	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
544404003875	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
544404003876	MPN+ (JAMM) motif; other site
544404003877	Zinc-binding site [ion binding]; other site
544404003878	Protein of unknown function (DUF987); Region: DUF987; pfam06174
544404003879	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
544404003880	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
544404003881	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
544404003882	Methyltransferase domain; Region: Methyltransf_27; pfam13708
544404003883	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
544404003884	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
544404003885	putative ligand binding site [chemical binding]; other site
544404003886	NAD binding site [chemical binding]; other site
544404003887	dimerization interface [polypeptide binding]; other site
544404003888	catalytic site [active]
544404003889	putative hydrolase; Validated; Region: PRK09248
544404003890	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
544404003891	active site
544404003892	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
544404003893	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
544404003894	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
544404003895	curli assembly protein CsgF; Provisional; Region: PRK10050
544404003896	curli assembly protein CsgE; Provisional; Region: PRK10386
544404003897	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
544404003898	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404003899	DNA binding residues [nucleotide binding]
544404003900	dimerization interface [polypeptide binding]; other site
544404003901	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
544404003902	Curlin associated repeat; Region: Curlin_rpt; pfam07012
544404003903	Curlin associated repeat; Region: Curlin_rpt; pfam07012
544404003904	major curlin subunit; Provisional; Region: csgA; PRK10051
544404003905	Curlin associated repeat; Region: Curlin_rpt; pfam07012
544404003906	Curlin associated repeat; Region: Curlin_rpt; pfam07012
544404003907	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
544404003908	Fimbrial protein; Region: Fimbrial; cl01416
544404003909	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
544404003910	putative ADP-ribose binding site [chemical binding]; other site
544404003911	putative active site [active]
544404003912	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
544404003913	PLD-like domain; Region: PLDc_2; pfam13091
544404003914	putative active site [active]
544404003915	catalytic site [active]
544404003916	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
544404003917	PLD-like domain; Region: PLDc_2; pfam13091
544404003918	putative active site [active]
544404003919	catalytic site [active]
544404003920	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
544404003921	Acyltransferase family; Region: Acyl_transf_3; pfam01757
544404003922	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
544404003923	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
544404003924	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
544404003925	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
544404003926	Ligand binding site; other site
544404003927	DXD motif; other site
544404003928	lipoprotein; Provisional; Region: PRK10175
544404003929	secY/secA suppressor protein; Provisional; Region: PRK11467
544404003930	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
544404003931	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
544404003932	putative acyl-acceptor binding pocket; other site
544404003933	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
544404003934	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
544404003935	active site residue [active]
544404003936	hypothetical protein; Provisional; Region: PRK03757
544404003937	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
544404003938	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
544404003939	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
544404003940	hydroxyglutarate oxidase; Provisional; Region: PRK11728
544404003941	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
544404003942	DNA damage-inducible protein I; Provisional; Region: PRK10597
544404003943	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
544404003944	active site
544404003945	substrate binding pocket [chemical binding]; other site
544404003946	dimer interface [polypeptide binding]; other site
544404003947	lipoprotein; Provisional; Region: PRK10598
544404003948	glutaredoxin 2; Provisional; Region: PRK10387
544404003949	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
544404003950	C-terminal domain interface [polypeptide binding]; other site
544404003951	GSH binding site (G-site) [chemical binding]; other site
544404003952	catalytic residues [active]
544404003953	putative dimer interface [polypeptide binding]; other site
544404003954	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
544404003955	N-terminal domain interface [polypeptide binding]; other site
544404003956	multidrug resistance protein MdtH; Provisional; Region: PRK11646
544404003957	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404003958	putative substrate translocation pore; other site
544404003959	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
544404003960	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
544404003961	hypothetical protein; Provisional; Region: PRK11239
544404003962	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
544404003963	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
544404003964	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
544404003965	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
544404003966	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
544404003967	MviN-like protein; Region: MVIN; pfam03023
544404003968	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
544404003969	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
544404003970	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
544404003971	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
544404003972	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
544404003973	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
544404003974	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
544404003975	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
544404003976	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
544404003977	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
544404003978	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
544404003979	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
544404003980	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
544404003981	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
544404003982	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
544404003983	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
544404003984	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
544404003985	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
544404003986	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
544404003987	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
544404003988	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
544404003989	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
544404003990	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
544404003991	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
544404003992	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
544404003993	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
544404003994	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
544404003995	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
544404003996	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
544404003997	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
544404003998	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
544404003999	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
544404004000	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
544404004001	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
544404004002	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
544404004003	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
544404004004	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
544404004005	homodimer interface [polypeptide binding]; other site
544404004006	oligonucleotide binding site [chemical binding]; other site
544404004007	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
544404004008	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
544404004009	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
544404004010	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404004011	RNA binding surface [nucleotide binding]; other site
544404004012	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
544404004013	active site
544404004014	Maf-like protein; Region: Maf; pfam02545
544404004015	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
544404004016	active site
544404004017	dimer interface [polypeptide binding]; other site
544404004018	hypothetical protein; Provisional; Region: PRK11193
544404004019	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
544404004020	putative phosphate acyltransferase; Provisional; Region: PRK05331
544404004021	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
544404004022	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
544404004023	dimer interface [polypeptide binding]; other site
544404004024	active site
544404004025	CoA binding pocket [chemical binding]; other site
544404004026	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
544404004027	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
544404004028	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
544404004029	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
544404004030	NAD(P) binding site [chemical binding]; other site
544404004031	homotetramer interface [polypeptide binding]; other site
544404004032	homodimer interface [polypeptide binding]; other site
544404004033	active site
544404004034	acyl carrier protein; Provisional; Region: acpP; PRK00982
544404004035	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
544404004036	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
544404004037	dimer interface [polypeptide binding]; other site
544404004038	active site
544404004039	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
544404004040	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
544404004041	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404004042	catalytic residue [active]
544404004043	conserved hypothetical protein, YceG family; Region: TIGR00247
544404004044	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
544404004045	dimerization interface [polypeptide binding]; other site
544404004046	thymidylate kinase; Validated; Region: tmk; PRK00698
544404004047	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
544404004048	TMP-binding site; other site
544404004049	ATP-binding site [chemical binding]; other site
544404004050	DNA polymerase III subunit delta'; Validated; Region: PRK07993
544404004051	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
544404004052	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
544404004053	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
544404004054	active site
544404004055	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
544404004056	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
544404004057	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404004058	active site turn [active]
544404004059	phosphorylation site [posttranslational modification]
544404004060	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
544404004061	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404004062	N-terminal plug; other site
544404004063	ligand-binding site [chemical binding]; other site
544404004064	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
544404004065	nucleotide binding site/active site [active]
544404004066	HIT family signature motif; other site
544404004067	catalytic residue [active]
544404004068	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
544404004069	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
544404004070	putative dimer interface [polypeptide binding]; other site
544404004071	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
544404004072	thiamine kinase; Region: ycfN_thiK; TIGR02721
544404004073	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
544404004074	active site
544404004075	substrate binding site [chemical binding]; other site
544404004076	ATP binding site [chemical binding]; other site
544404004077	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
544404004078	beta-hexosaminidase; Provisional; Region: PRK05337
544404004079	hypothetical protein; Provisional; Region: PRK04940
544404004080	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
544404004081	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404004082	hypothetical protein; Provisional; Region: PRK11280
544404004083	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
544404004084	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404004085	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404004086	L,D-transpeptidase; Provisional; Region: PRK10260
544404004087	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404004088	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404004089	transcription-repair coupling factor; Provisional; Region: PRK10689
544404004090	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
544404004091	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404004092	ATP binding site [chemical binding]; other site
544404004093	putative Mg++ binding site [ion binding]; other site
544404004094	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404004095	nucleotide binding region [chemical binding]; other site
544404004096	ATP-binding site [chemical binding]; other site
544404004097	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
544404004098	Predicted membrane protein [Function unknown]; Region: COG4763
544404004099	Acyltransferase family; Region: Acyl_transf_3; pfam01757
544404004100	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
544404004101	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
544404004102	FtsX-like permease family; Region: FtsX; pfam02687
544404004103	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
544404004104	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
544404004105	Walker A/P-loop; other site
544404004106	ATP binding site [chemical binding]; other site
544404004107	Q-loop/lid; other site
544404004108	ABC transporter signature motif; other site
544404004109	Walker B; other site
544404004110	D-loop; other site
544404004111	H-loop/switch region; other site
544404004112	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
544404004113	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
544404004114	FtsX-like permease family; Region: FtsX; pfam02687
544404004115	fructokinase; Reviewed; Region: PRK09557
544404004116	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404004117	nucleotide binding site [chemical binding]; other site
544404004118	NAD-dependent deacetylase; Provisional; Region: PRK00481
544404004119	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
544404004120	NAD+ binding site [chemical binding]; other site
544404004121	substrate binding site [chemical binding]; other site
544404004122	Zn binding site [ion binding]; other site
544404004123	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
544404004124	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
544404004125	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
544404004126	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404004127	dimer interface [polypeptide binding]; other site
544404004128	conserved gate region; other site
544404004129	putative PBP binding loops; other site
544404004130	ABC-ATPase subunit interface; other site
544404004131	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
544404004132	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404004133	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
544404004134	dimer interface [polypeptide binding]; other site
544404004135	active site
544404004136	Int/Topo IB signature motif; other site
544404004137	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404004138	active site
544404004139	substrate binding site [chemical binding]; other site
544404004140	catalytic site [active]
544404004141	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
544404004142	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404004143	sequence-specific DNA binding site [nucleotide binding]; other site
544404004144	salt bridge; other site
544404004145	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404004146	Pyocin large subunit [General function prediction only]; Region: COG5529
544404004147	primosomal protein DnaI; Provisional; Region: PRK02854
544404004148	Replication protein P; Region: Phage_lambda_P; pfam06992
544404004149	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404004150	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
544404004151	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
544404004152	Protein of unknown function (DUF551); Region: DUF551; pfam04448
544404004153	Hok/gef family; Region: HOK_GEF; pfam01848
544404004154	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404004155	Endodeoxyribonuclease RusA; Region: RusA; cl01885
544404004156	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404004157	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
544404004158	Protein of unknown function (DUF826); Region: DUF826; pfam05696
544404004159	Lysis protein S; Region: Lysis_S; pfam04971
544404004160	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
544404004161	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404004162	catalytic residues [active]
544404004163	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
544404004164	ORF11CD3 domain; Region: ORF11CD3; pfam10549
544404004165	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404004166	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
544404004167	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
544404004168	active site
544404004169	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
544404004170	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
544404004171	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
544404004172	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
544404004173	Phage capsid family; Region: Phage_capsid; pfam05065
544404004174	Phage-related protein [Function unknown]; Region: COG4695
544404004175	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
544404004176	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
544404004177	oligomerization interface [polypeptide binding]; other site
544404004178	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
544404004179	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
544404004180	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
544404004181	Immunoglobulin domain; Region: Ig_3; pfam13927
544404004182	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
544404004183	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
544404004184	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404004185	tape measure domain; Region: tape_meas_nterm; TIGR02675
544404004186	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
544404004187	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404004188	Phage-related protein [Function unknown]; Region: COG4718
544404004189	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404004190	Mnt; Region: mnt; PHA01513
544404004191	Arc-like DNA binding domain; Region: Arc; pfam03869
544404004192	Prophage antirepressor [Transcription]; Region: COG3617
544404004193	BRO family, N-terminal domain; Region: Bro-N; smart01040
544404004194	Phage anti-repressor protein [Transcription]; Region: COG3561
544404004195	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404004196	MPN+ (JAMM) motif; other site
544404004197	Zinc-binding site [ion binding]; other site
544404004198	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404004199	NlpC/P60 family; Region: NLPC_P60; cl17555
544404004200	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404004201	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
544404004202	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404004203	SopA-like central domain; Region: SopA; pfam13981
544404004204	SopA-like catalytic domain; Region: SopA_C; pfam13979
544404004205	IS2 transposase TnpB; Reviewed; Region: PRK09409
544404004206	HTH-like domain; Region: HTH_21; pfam13276
544404004207	Integrase core domain; Region: rve; pfam00665
544404004208	Integrase core domain; Region: rve_3; pfam13683
544404004209	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
544404004210	type III secretion protein GogB; Provisional; Region: PRK15386
544404004211	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
544404004212	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404004213	dimer interface [polypeptide binding]; other site
544404004214	conserved gate region; other site
544404004215	putative PBP binding loops; other site
544404004216	ABC-ATPase subunit interface; other site
544404004217	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
544404004218	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404004219	Walker A/P-loop; other site
544404004220	ATP binding site [chemical binding]; other site
544404004221	Q-loop/lid; other site
544404004222	ABC transporter signature motif; other site
544404004223	Walker B; other site
544404004224	D-loop; other site
544404004225	H-loop/switch region; other site
544404004226	TOBE domain; Region: TOBE_2; pfam08402
544404004227	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
544404004228	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
544404004229	metal binding site [ion binding]; metal-binding site
544404004230	dimer interface [polypeptide binding]; other site
544404004231	Uncharacterized conserved protein [Function unknown]; Region: COG2850
544404004232	Cupin-like domain; Region: Cupin_8; pfam13621
544404004233	integrase; Provisional; Region: PRK09692
544404004234	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404004235	active site
544404004236	Int/Topo IB signature motif; other site
544404004237	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
544404004238	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
544404004239	AAA domain; Region: AAA_25; pfam13481
544404004240	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
544404004241	Walker A motif; other site
544404004242	ATP binding site [chemical binding]; other site
544404004243	Walker B motif; other site
544404004244	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
544404004245	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
544404004246	ssDNA binding site [nucleotide binding]; other site
544404004247	dimer interface [polypeptide binding]; other site
544404004248	tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404004249	PerC transcriptional activator; Region: PerC; pfam06069
544404004250	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
544404004251	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
544404004252	Phage DNA packaging protein Nu1; Region: Phage_Nu1; cl01720
544404004253	sensor protein PhoQ; Provisional; Region: PRK10815
544404004254	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
544404004255	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
544404004256	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
544404004257	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404004258	ATP binding site [chemical binding]; other site
544404004259	Mg2+ binding site [ion binding]; other site
544404004260	G-X-G motif; other site
544404004261	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
544404004262	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404004263	active site
544404004264	phosphorylation site [posttranslational modification]
544404004265	intermolecular recognition site; other site
544404004266	dimerization interface [polypeptide binding]; other site
544404004267	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404004268	DNA binding site [nucleotide binding]
544404004269	adenylosuccinate lyase; Provisional; Region: PRK09285
544404004270	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
544404004271	tetramer interface [polypeptide binding]; other site
544404004272	active site
544404004273	putative lysogenization regulator; Reviewed; Region: PRK00218
544404004274	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
544404004275	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
544404004276	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
544404004277	nudix motif; other site
544404004278	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
544404004279	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
544404004280	probable active site [active]
544404004281	isocitrate dehydrogenase; Validated; Region: PRK07362
544404004282	isocitrate dehydrogenase; Reviewed; Region: PRK07006
544404004283	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
544404004284	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404004285	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
544404004286	dimer interface [polypeptide binding]; other site
544404004287	active site
544404004288	Int/Topo IB signature motif; other site
544404004289	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
544404004290	Replication protein P; Region: Phage_lambda_P; pfam06992
544404004291	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
544404004292	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
544404004293	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
544404004294	catalytic residues [active]
544404004295	catalytic nucleophile [active]
544404004296	Recombinase; Region: Recombinase; pfam07508
544404004297	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
544404004298	hypothetical protein; Provisional; Region: PRK09741
544404004299	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
544404004300	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
544404004301	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
544404004302	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
544404004303	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404004304	catalytic residue [active]
544404004305	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404004306	Bor protein; Region: Lambda_Bor; pfam06291
544404004307	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
544404004308	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
544404004309	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
544404004310	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
544404004311	gpW; Region: gpW; pfam02831
544404004312	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404004313	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404004314	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
544404004315	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
544404004316	tandem repeat interface [polypeptide binding]; other site
544404004317	oligomer interface [polypeptide binding]; other site
544404004318	active site residues [active]
544404004319	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
544404004320	DNA packaging protein FI; Region: Packaging_FI; pfam14000
544404004321	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
544404004322	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
544404004323	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
544404004324	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404004325	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404004326	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
544404004327	Minor tail protein T; Region: Phage_tail_T; pfam06223
544404004328	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404004329	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404004330	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404004331	Phage-related protein [Function unknown]; Region: COG4718
544404004332	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404004333	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404004334	MPN+ (JAMM) motif; other site
544404004335	Zinc-binding site [ion binding]; other site
544404004336	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404004337	NlpC/P60 family; Region: NLPC_P60; cl17555
544404004338	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404004339	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404004340	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404004341	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404004342	Fibronectin type III protein; Region: DUF3672; pfam12421
544404004343	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
544404004344	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404004345	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
544404004346	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
544404004347	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
544404004348	Phage Tail Collar Domain; Region: Collar; pfam07484
544404004349	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404004350	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
544404004351	dimanganese center [ion binding]; other site
544404004352	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
544404004353	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
544404004354	dimerization interface [polypeptide binding]; other site
544404004355	metal binding site [ion binding]; metal-binding site
544404004356	General stress protein [General function prediction only]; Region: GsiB; COG3729
544404004357	Methyltransferase domain; Region: Methyltransf_31; pfam13847
544404004358	Methyltransferase domain; Region: Methyltransf_12; pfam08242
544404004359	S-adenosylmethionine binding site [chemical binding]; other site
544404004360	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404004361	Transposase; Region: HTH_Tnp_1; pfam01527
544404004362	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404004363	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404004364	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404004365	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404004366	homodimer interface [polypeptide binding]; other site
544404004367	putative GKAP docking site [polypeptide binding]; other site
544404004368	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404004369	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404004370	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404004371	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404004372	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404004373	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
544404004374	TAP-like protein; Region: Abhydrolase_4; pfam08386
544404004375	outer membrane protease; Reviewed; Region: PRK10993
544404004376	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
544404004377	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404004378	sequence-specific DNA binding site [nucleotide binding]; other site
544404004379	salt bridge; other site
544404004380	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
544404004381	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
544404004382	cell division inhibitor MinD; Provisional; Region: PRK10818
544404004383	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
544404004384	Switch I; other site
544404004385	Switch II; other site
544404004386	septum formation inhibitor; Reviewed; Region: minC; PRK03511
544404004387	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
544404004388	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
544404004389	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
544404004390	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
544404004391	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
544404004392	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
544404004393	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
544404004394	hypothetical protein; Provisional; Region: PRK10691
544404004395	hypothetical protein; Provisional; Region: PRK05170
544404004396	hemolysin E; Provisional; Region: hlyE; PRK11376
544404004397	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
544404004398	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404004399	Catalytic site [active]
544404004400	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
544404004401	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
544404004402	active site
544404004403	DNA binding site [nucleotide binding]
544404004404	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
544404004405	disulfide bond formation protein B; Provisional; Region: PRK01749
544404004406	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
544404004407	transmembrane helices; other site
544404004408	fatty acid metabolism regulator; Provisional; Region: PRK04984
544404004409	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404004410	DNA-binding site [nucleotide binding]; DNA binding site
544404004411	FadR C-terminal domain; Region: FadR_C; pfam07840
544404004412	SpoVR family protein; Provisional; Region: PRK11767
544404004413	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
544404004414	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
544404004415	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404004416	alanine racemase; Reviewed; Region: dadX; PRK03646
544404004417	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
544404004418	active site
544404004419	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
544404004420	substrate binding site [chemical binding]; other site
544404004421	catalytic residues [active]
544404004422	dimer interface [polypeptide binding]; other site
544404004423	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
544404004424	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
544404004425	TrkA-C domain; Region: TrkA_C; pfam02080
544404004426	Transporter associated domain; Region: CorC_HlyC; smart01091
544404004427	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
544404004428	dimer interface [polypeptide binding]; other site
544404004429	catalytic triad [active]
544404004430	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
544404004431	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404004432	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404004433	catalytic residue [active]
544404004434	GTP-binding protein YchF; Reviewed; Region: PRK09601
544404004435	YchF GTPase; Region: YchF; cd01900
544404004436	G1 box; other site
544404004437	GTP/Mg2+ binding site [chemical binding]; other site
544404004438	Switch I region; other site
544404004439	G2 box; other site
544404004440	Switch II region; other site
544404004441	G3 box; other site
544404004442	G4 box; other site
544404004443	G5 box; other site
544404004444	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
544404004445	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
544404004446	putative active site [active]
544404004447	catalytic residue [active]
544404004448	hypothetical protein; Provisional; Region: PRK10692
544404004449	putative transporter; Provisional; Region: PRK11660
544404004450	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
544404004451	Sulfate transporter family; Region: Sulfate_transp; pfam00916
544404004452	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
544404004453	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
544404004454	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
544404004455	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404004456	active site
544404004457	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
544404004458	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
544404004459	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
544404004460	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
544404004461	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
544404004462	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
544404004463	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
544404004464	tRNA; other site
544404004465	putative tRNA binding site [nucleotide binding]; other site
544404004466	putative NADP binding site [chemical binding]; other site
544404004467	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
544404004468	peptide chain release factor 1; Validated; Region: prfA; PRK00591
544404004469	This domain is found in peptide chain release factors; Region: PCRF; smart00937
544404004470	RF-1 domain; Region: RF-1; pfam00472
544404004471	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
544404004472	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404004473	hypothetical protein; Provisional; Region: PRK10278
544404004474	hypothetical protein; Provisional; Region: PRK10941
544404004475	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
544404004476	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
544404004477	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
544404004478	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
544404004479	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
544404004480	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
544404004481	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
544404004482	cation transport regulator; Reviewed; Region: chaB; PRK09582
544404004483	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
544404004484	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
544404004485	putative active site pocket [active]
544404004486	dimerization interface [polypeptide binding]; other site
544404004487	putative catalytic residue [active]
544404004488	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
544404004489	putative invasin; Provisional; Region: PRK10177
544404004490	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
544404004491	transcriptional regulator NarL; Provisional; Region: PRK10651
544404004492	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404004493	active site
544404004494	phosphorylation site [posttranslational modification]
544404004495	intermolecular recognition site; other site
544404004496	dimerization interface [polypeptide binding]; other site
544404004497	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404004498	DNA binding residues [nucleotide binding]
544404004499	dimerization interface [polypeptide binding]; other site
544404004500	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
544404004501	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
544404004502	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404004503	dimerization interface [polypeptide binding]; other site
544404004504	Histidine kinase; Region: HisKA_3; pfam07730
544404004505	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404004506	ATP binding site [chemical binding]; other site
544404004507	Mg2+ binding site [ion binding]; other site
544404004508	G-X-G motif; other site
544404004509	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
544404004510	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
544404004511	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
544404004512	[4Fe-4S] binding site [ion binding]; other site
544404004513	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404004514	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404004515	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404004516	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
544404004517	molybdopterin cofactor binding site; other site
544404004518	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
544404004519	4Fe-4S binding domain; Region: Fer4; cl02805
544404004520	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
544404004521	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
544404004522	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
544404004523	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
544404004524	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
544404004525	putative active site [active]
544404004526	putative substrate binding site [chemical binding]; other site
544404004527	putative cosubstrate binding site; other site
544404004528	catalytic site [active]
544404004529	SEC-C motif; Region: SEC-C; pfam02810
544404004530	hypothetical protein; Provisional; Region: PRK04233
544404004531	hypothetical protein; Provisional; Region: PRK10279
544404004532	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
544404004533	active site
544404004534	nucleophile elbow; other site
544404004535	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404004536	active site
544404004537	response regulator of RpoS; Provisional; Region: PRK10693
544404004538	phosphorylation site [posttranslational modification]
544404004539	intermolecular recognition site; other site
544404004540	dimerization interface [polypeptide binding]; other site
544404004541	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
544404004542	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
544404004543	active site
544404004544	tetramer interface; other site
544404004545	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
544404004546	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
544404004547	thymidine kinase; Provisional; Region: PRK04296
544404004548	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
544404004549	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
544404004550	putative catalytic cysteine [active]
544404004551	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
544404004552	putative active site [active]
544404004553	metal binding site [ion binding]; metal-binding site
544404004554	hypothetical protein; Provisional; Region: PRK11111
544404004555	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
544404004556	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
544404004557	peptide binding site [polypeptide binding]; other site
544404004558	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
544404004559	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404004560	dimer interface [polypeptide binding]; other site
544404004561	conserved gate region; other site
544404004562	putative PBP binding loops; other site
544404004563	ABC-ATPase subunit interface; other site
544404004564	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
544404004565	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
544404004566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404004567	dimer interface [polypeptide binding]; other site
544404004568	conserved gate region; other site
544404004569	putative PBP binding loops; other site
544404004570	ABC-ATPase subunit interface; other site
544404004571	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
544404004572	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404004573	Walker A/P-loop; other site
544404004574	ATP binding site [chemical binding]; other site
544404004575	Q-loop/lid; other site
544404004576	ABC transporter signature motif; other site
544404004577	Walker B; other site
544404004578	D-loop; other site
544404004579	H-loop/switch region; other site
544404004580	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
544404004581	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
544404004582	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404004583	Walker A/P-loop; other site
544404004584	ATP binding site [chemical binding]; other site
544404004585	Q-loop/lid; other site
544404004586	ABC transporter signature motif; other site
544404004587	Walker B; other site
544404004588	D-loop; other site
544404004589	H-loop/switch region; other site
544404004590	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
544404004591	dsDNA-mimic protein; Reviewed; Region: PRK05094
544404004592	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
544404004593	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
544404004594	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
544404004595	putative active site [active]
544404004596	catalytic site [active]
544404004597	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
544404004598	putative active site [active]
544404004599	catalytic site [active]
544404004600	voltage-gated potassium channel; Provisional; Region: PRK10537
544404004601	Ion channel; Region: Ion_trans_2; pfam07885
544404004602	TrkA-N domain; Region: TrkA_N; pfam02254
544404004603	YciI-like protein; Reviewed; Region: PRK11370
544404004604	transport protein TonB; Provisional; Region: PRK10819
544404004605	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
544404004606	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
544404004607	intracellular septation protein A; Reviewed; Region: PRK00259
544404004608	hypothetical protein; Provisional; Region: PRK02868
544404004609	outer membrane protein W; Provisional; Region: PRK10959
544404004610	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
544404004611	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404004612	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
544404004613	dimer interface [polypeptide binding]; other site
544404004614	active site
544404004615	Int/Topo IB signature motif; other site
544404004616	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404004617	active site
544404004618	catalytic site [active]
544404004619	substrate binding site [chemical binding]; other site
544404004620	transcriptional repressor DicA; Reviewed; Region: PRK09706
544404004621	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404004622	sequence-specific DNA binding site [nucleotide binding]; other site
544404004623	salt bridge; other site
544404004624	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
544404004625	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404004626	Pyocin large subunit [General function prediction only]; Region: COG5529
544404004627	Helix-turn-helix domain; Region: HTH_36; pfam13730
544404004628	primosomal protein DnaI; Provisional; Region: PRK02854
544404004629	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404004630	Accessory colonization factor AcfC, contains ABC-type periplasmic domain [General function prediction only]; Region: AcfC; COG4588
544404004631	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
544404004632	Hok/gef family; Region: HOK_GEF; pfam01848
544404004633	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404004634	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
544404004635	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
544404004636	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404004637	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
544404004638	DNA methylase; Region: N6_N4_Mtase; pfam01555
544404004639	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
544404004640	Lysis protein S; Region: Lysis_S; pfam04971
544404004641	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
544404004642	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404004643	catalytic residues [active]
544404004644	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
544404004645	ORF11CD3 domain; Region: ORF11CD3; pfam10549
544404004646	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404004647	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
544404004648	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
544404004649	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404004650	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404004651	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
544404004652	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
544404004653	tandem repeat interface [polypeptide binding]; other site
544404004654	oligomer interface [polypeptide binding]; other site
544404004655	active site residues [active]
544404004656	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
544404004657	DNA packaging protein FI; Region: Packaging_FI; pfam14000
544404004658	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
544404004659	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
544404004660	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
544404004661	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404004662	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404004663	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
544404004664	Minor tail protein T; Region: Phage_tail_T; cl05636
544404004665	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404004666	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404004667	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404004668	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
544404004669	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404004670	Phage-related protein [Function unknown]; Region: COG4718
544404004671	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404004672	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404004673	MPN+ (JAMM) motif; other site
544404004674	Zinc-binding site [ion binding]; other site
544404004675	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404004676	NlpC/P60 family; Region: NLPC_P60; cl17555
544404004677	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404004678	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404004679	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404004680	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
544404004681	Interdomain contacts; other site
544404004682	Cytokine receptor motif; other site
544404004683	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404004684	Fibronectin type III protein; Region: DUF3672; pfam12421
544404004685	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
544404004686	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404004687	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404004688	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404004689	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404004690	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404004691	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
544404004692	dimer interface [polypeptide binding]; other site
544404004693	active site
544404004694	Int/Topo IB signature motif; other site
544404004695	hypothetical protein; Provisional; Region: PHA03031
544404004696	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404004697	homodimer interface [polypeptide binding]; other site
544404004698	putative GKAP docking site [polypeptide binding]; other site
544404004699	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404004700	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404004701	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404004702	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404004703	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404004704	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404004705	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404004706	Transposase; Region: HTH_Tnp_1; pfam01527
544404004707	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404004708	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404004709	IpaB/EvcA family; Region: IpaB_EvcA; pfam03278
544404004710	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
544404004711	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404004712	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
544404004713	dimer interface [polypeptide binding]; other site
544404004714	active site
544404004715	Int/Topo IB signature motif; other site
544404004716	exonuclease VIII; Reviewed; Region: PRK09709
544404004717	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
544404004718	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404004719	active site
544404004720	substrate binding site [chemical binding]; other site
544404004721	catalytic site [active]
544404004722	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
544404004723	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
544404004724	transcriptional repressor DicA; Reviewed; Region: PRK09706
544404004725	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404004726	non-specific DNA binding site [nucleotide binding]; other site
544404004727	salt bridge; other site
544404004728	sequence-specific DNA binding site [nucleotide binding]; other site
544404004729	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404004730	Pyocin large subunit [General function prediction only]; Region: COG5529
544404004731	Helix-turn-helix domain; Region: HTH_36; pfam13730
544404004732	primosomal protein DnaI; Provisional; Region: PRK02854
544404004733	Replication protein P; Region: Phage_lambda_P; pfam06992
544404004734	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404004735	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
544404004736	Protein of unknown function (DUF551); Region: DUF551; pfam04448
544404004737	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404004738	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
544404004739	Antitermination protein; Region: Antiterm; pfam03589
544404004740	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
544404004741	MarR family; Region: MarR_2; cl17246
544404004742	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404004743	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
544404004744	DNA methylase; Region: N6_N4_Mtase; pfam01555
544404004745	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
544404004746	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404004747	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404004748	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
544404004749	Protein of unknown function (DUF826); Region: DUF826; pfam05696
544404004750	Lysis protein S; Region: Lysis_S; pfam04971
544404004751	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404004752	catalytic residues [active]
544404004753	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404004754	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
544404004755	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
544404004756	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404004757	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404004758	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
544404004759	Clp protease; Region: CLP_protease; pfam00574
544404004760	oligomer interface [polypeptide binding]; other site
544404004761	active site residues [active]
544404004762	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
544404004763	Uncharacterized conserved protein [Function unknown]; Region: COG5471
544404004764	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
544404004765	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
544404004766	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
544404004767	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404004768	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404004769	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
544404004770	Minor tail protein T; Region: Phage_tail_T; cl05636
544404004771	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404004772	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404004773	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404004774	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404004775	Phage-related protein [Function unknown]; Region: COG4718
544404004776	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404004777	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404004778	MPN+ (JAMM) motif; other site
544404004779	Zinc-binding site [ion binding]; other site
544404004780	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404004781	NlpC/P60 family; Region: NLPC_P60; cl17555
544404004782	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404004783	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404004784	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404004785	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404004786	Fibronectin type III protein; Region: DUF3672; pfam12421
544404004787	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404004788	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404004789	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
544404004790	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404004791	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404004792	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
544404004793	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
544404004794	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
544404004795	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
544404004796	serine/threonine protein kinase; Provisional; Region: PRK14879
544404004797	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
544404004798	OmpW family; Region: OmpW; cl17427
544404004799	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
544404004800	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
544404004801	dimerization interface [polypeptide binding]; other site
544404004802	metal binding site [ion binding]; metal-binding site
544404004803	General stress protein [General function prediction only]; Region: GsiB; COG3729
544404004804	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
544404004805	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
544404004806	substrate binding site [chemical binding]; other site
544404004807	active site
544404004808	catalytic residues [active]
544404004809	heterodimer interface [polypeptide binding]; other site
544404004810	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
544404004811	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
544404004812	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404004813	catalytic residue [active]
544404004814	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
544404004815	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
544404004816	active site
544404004817	ribulose/triose binding site [chemical binding]; other site
544404004818	phosphate binding site [ion binding]; other site
544404004819	substrate (anthranilate) binding pocket [chemical binding]; other site
544404004820	product (indole) binding pocket [chemical binding]; other site
544404004821	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
544404004822	active site
544404004823	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
544404004824	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
544404004825	glutamine binding [chemical binding]; other site
544404004826	catalytic triad [active]
544404004827	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
544404004828	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
544404004829	anthranilate synthase component I; Provisional; Region: PRK13564
544404004830	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
544404004831	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
544404004832	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
544404004833	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
544404004834	active site
544404004835	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
544404004836	hypothetical protein; Provisional; Region: PRK11630
544404004837	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
544404004838	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
544404004839	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404004840	RNA binding surface [nucleotide binding]; other site
544404004841	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
544404004842	probable active site [active]
544404004843	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
544404004844	cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Validated; Region: PRK05986
544404004845	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
544404004846	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
544404004847	NADP binding site [chemical binding]; other site
544404004848	homodimer interface [polypeptide binding]; other site
544404004849	active site
544404004850	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
544404004851	putative inner membrane peptidase; Provisional; Region: PRK11778
544404004852	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
544404004853	tandem repeat interface [polypeptide binding]; other site
544404004854	oligomer interface [polypeptide binding]; other site
544404004855	active site residues [active]
544404004856	hypothetical protein; Provisional; Region: PRK11037
544404004857	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
544404004858	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
544404004859	active site
544404004860	interdomain interaction site; other site
544404004861	putative metal-binding site [ion binding]; other site
544404004862	nucleotide binding site [chemical binding]; other site
544404004863	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
544404004864	domain I; other site
544404004865	DNA binding groove [nucleotide binding]
544404004866	phosphate binding site [ion binding]; other site
544404004867	domain II; other site
544404004868	domain III; other site
544404004869	nucleotide binding site [chemical binding]; other site
544404004870	catalytic site [active]
544404004871	domain IV; other site
544404004872	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
544404004873	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
544404004874	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
544404004875	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
544404004876	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
544404004877	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404004878	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
544404004879	substrate binding site [chemical binding]; other site
544404004880	putative dimerization interface [polypeptide binding]; other site
544404004881	aconitate hydratase; Validated; Region: PRK09277
544404004882	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
544404004883	substrate binding site [chemical binding]; other site
544404004884	ligand binding site [chemical binding]; other site
544404004885	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
544404004886	substrate binding site [chemical binding]; other site
544404004887	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
544404004888	dimerization interface [polypeptide binding]; other site
544404004889	active site
544404004890	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
544404004891	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
544404004892	active site
544404004893	Predicted membrane protein [Function unknown]; Region: COG3771
544404004894	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
544404004895	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
544404004896	TPR motif; other site
544404004897	binding surface
544404004898	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404004899	binding surface
544404004900	TPR motif; other site
544404004901	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
544404004902	active site
544404004903	dimer interface [polypeptide binding]; other site
544404004904	translation initiation factor Sui1; Validated; Region: PRK06824
544404004905	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
544404004906	putative rRNA binding site [nucleotide binding]; other site
544404004907	lipoprotein; Provisional; Region: PRK10540
544404004908	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
544404004909	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
544404004910	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404004911	hypothetical protein; Provisional; Region: PRK13658
544404004912	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404004913	PAS domain; Region: PAS_9; pfam13426
544404004914	putative active site [active]
544404004915	heme pocket [chemical binding]; other site
544404004916	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404004917	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404004918	metal binding site [ion binding]; metal-binding site
544404004919	active site
544404004920	I-site; other site
544404004921	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404004922	exoribonuclease II; Provisional; Region: PRK05054
544404004923	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
544404004924	RNB domain; Region: RNB; pfam00773
544404004925	S1 RNA binding domain; Region: S1; pfam00575
544404004926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
544404004927	Uncharacterized conserved protein [Function unknown]; Region: COG2128
544404004928	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
544404004929	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
544404004930	NAD binding site [chemical binding]; other site
544404004931	homotetramer interface [polypeptide binding]; other site
544404004932	homodimer interface [polypeptide binding]; other site
544404004933	substrate binding site [chemical binding]; other site
544404004934	active site
544404004935	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
544404004936	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404004937	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
544404004938	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404004939	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404004940	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
544404004941	Protein export membrane protein; Region: SecD_SecF; cl14618
544404004942	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
544404004943	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
544404004944	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404004945	putative substrate translocation pore; other site
544404004946	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
544404004947	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404004948	Walker A/P-loop; other site
544404004949	ATP binding site [chemical binding]; other site
544404004950	Q-loop/lid; other site
544404004951	ABC transporter signature motif; other site
544404004952	Walker B; other site
544404004953	D-loop; other site
544404004954	H-loop/switch region; other site
544404004955	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
544404004956	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404004957	Walker A/P-loop; other site
544404004958	ATP binding site [chemical binding]; other site
544404004959	Q-loop/lid; other site
544404004960	ABC transporter signature motif; other site
544404004961	Walker B; other site
544404004962	D-loop; other site
544404004963	H-loop/switch region; other site
544404004964	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
544404004965	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
544404004966	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
544404004967	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404004968	dimer interface [polypeptide binding]; other site
544404004969	conserved gate region; other site
544404004970	putative PBP binding loops; other site
544404004971	ABC-ATPase subunit interface; other site
544404004972	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
544404004973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404004974	dimer interface [polypeptide binding]; other site
544404004975	conserved gate region; other site
544404004976	putative PBP binding loops; other site
544404004977	ABC-ATPase subunit interface; other site
544404004978	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
544404004979	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
544404004980	peptide binding site [polypeptide binding]; other site
544404004981	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
544404004982	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
544404004983	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
544404004984	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
544404004985	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
544404004986	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
544404004987	catalytic triad [active]
544404004988	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
544404004989	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404004990	non-specific DNA binding site [nucleotide binding]; other site
544404004991	salt bridge; other site
544404004992	sequence-specific DNA binding site [nucleotide binding]; other site
544404004993	Cupin domain; Region: Cupin_2; pfam07883
544404004994	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
544404004995	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
544404004996	NAD(P) binding site [chemical binding]; other site
544404004997	catalytic residues [active]
544404004998	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
544404004999	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
544404005000	4-aminobutyrate transaminase; Provisional; Region: PRK09792
544404005001	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404005002	inhibitor-cofactor binding pocket; inhibition site
544404005003	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404005004	catalytic residue [active]
544404005005	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
544404005006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404005007	Walker A motif; other site
544404005008	ATP binding site [chemical binding]; other site
544404005009	Walker B motif; other site
544404005010	arginine finger; other site
544404005011	phage shock protein PspA; Provisional; Region: PRK10698
544404005012	phage shock protein B; Provisional; Region: pspB; PRK09458
544404005013	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
544404005014	phage shock protein C; Region: phageshock_pspC; TIGR02978
544404005015	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
544404005016	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
544404005017	active site residue [active]
544404005018	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
544404005019	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404005020	dimer interface [polypeptide binding]; other site
544404005021	conserved gate region; other site
544404005022	putative PBP binding loops; other site
544404005023	ABC-ATPase subunit interface; other site
544404005024	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
544404005025	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404005026	dimer interface [polypeptide binding]; other site
544404005027	conserved gate region; other site
544404005028	putative PBP binding loops; other site
544404005029	ABC-ATPase subunit interface; other site
544404005030	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404005031	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
544404005032	putative NAD(P) binding site [chemical binding]; other site
544404005033	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
544404005034	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
544404005035	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
544404005036	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
544404005037	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
544404005038	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
544404005039	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
544404005040	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
544404005041	beta-phosphoglucomutase; Region: bPGM; TIGR01990
544404005042	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404005043	motif II; other site
544404005044	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
544404005045	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
544404005046	Walker A/P-loop; other site
544404005047	ATP binding site [chemical binding]; other site
544404005048	Q-loop/lid; other site
544404005049	ABC transporter signature motif; other site
544404005050	Walker B; other site
544404005051	D-loop; other site
544404005052	H-loop/switch region; other site
544404005053	TOBE domain; Region: TOBE_2; pfam08402
544404005054	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
544404005055	Transcriptional regulators [Transcription]; Region: PurR; COG1609
544404005056	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404005057	DNA binding site [nucleotide binding]
544404005058	domain linker motif; other site
544404005059	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
544404005060	putative dimerization interface [polypeptide binding]; other site
544404005061	putative ligand binding site [chemical binding]; other site
544404005062	Predicted ATPase [General function prediction only]; Region: COG3106
544404005063	hypothetical protein; Provisional; Region: PRK05415
544404005064	TIGR01620 family protein; Region: hyp_HI0043
544404005065	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
544404005066	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
544404005067	putative aromatic amino acid binding site; other site
544404005068	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404005069	Walker A motif; other site
544404005070	ATP binding site [chemical binding]; other site
544404005071	Walker B motif; other site
544404005072	arginine finger; other site
544404005073	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
544404005074	dimer interface [polypeptide binding]; other site
544404005075	catalytic triad [active]
544404005076	peroxidatic and resolving cysteines [active]
544404005077	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
544404005078	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
544404005079	active site
544404005080	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
544404005081	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
544404005082	putative active site [active]
544404005083	Zn binding site [ion binding]; other site
544404005084	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
544404005085	NADH(P)-binding; Region: NAD_binding_10; pfam13460
544404005086	putative NAD(P) binding site [chemical binding]; other site
544404005087	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
544404005088	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
544404005089	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404005090	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404005091	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
544404005092	putative effector binding pocket; other site
544404005093	putative dimerization interface [polypeptide binding]; other site
544404005094	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
544404005095	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
544404005096	peptide binding site [polypeptide binding]; other site
544404005097	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
544404005098	Mechanosensitive ion channel; Region: MS_channel; pfam00924
544404005099	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
544404005100	universal stress protein UspE; Provisional; Region: PRK11175
544404005101	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404005102	Ligand Binding Site [chemical binding]; other site
544404005103	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404005104	Ligand Binding Site [chemical binding]; other site
544404005105	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
544404005106	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
544404005107	ligand binding site [chemical binding]; other site
544404005108	flexible hinge region; other site
544404005109	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
544404005110	putative switch regulator; other site
544404005111	non-specific DNA interactions [nucleotide binding]; other site
544404005112	DNA binding site [nucleotide binding]
544404005113	sequence specific DNA binding site [nucleotide binding]; other site
544404005114	putative cAMP binding site [chemical binding]; other site
544404005115	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
544404005116	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
544404005117	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
544404005118	DNA binding site [nucleotide binding]
544404005119	active site
544404005120	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
544404005121	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
544404005122	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
544404005123	amidohydrolase; Region: amidohydrolases; TIGR01891
544404005124	putative metal binding site [ion binding]; other site
544404005125	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
544404005126	amidohydrolase; Region: amidohydrolases; TIGR01891
544404005127	putative metal binding site [ion binding]; other site
544404005128	dimer interface [polypeptide binding]; other site
544404005129	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
544404005130	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404005131	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
544404005132	putative substrate binding pocket [chemical binding]; other site
544404005133	putative dimerization interface [polypeptide binding]; other site
544404005134	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
544404005135	Smr domain; Region: Smr; pfam01713
544404005136	PAS domain S-box; Region: sensory_box; TIGR00229
544404005137	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404005138	putative active site [active]
544404005139	heme pocket [chemical binding]; other site
544404005140	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404005141	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404005142	metal binding site [ion binding]; metal-binding site
544404005143	active site
544404005144	I-site; other site
544404005145	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
544404005146	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
544404005147	Cl binding site [ion binding]; other site
544404005148	oligomer interface [polypeptide binding]; other site
544404005149	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
544404005150	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
544404005151	ATP binding site [chemical binding]; other site
544404005152	Mg++ binding site [ion binding]; other site
544404005153	motif III; other site
544404005154	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404005155	nucleotide binding region [chemical binding]; other site
544404005156	ATP-binding site [chemical binding]; other site
544404005157	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
544404005158	putative RNA binding site [nucleotide binding]; other site
544404005159	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
544404005160	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
544404005161	Ligand Binding Site [chemical binding]; other site
544404005162	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404005163	Ligand Binding Site [chemical binding]; other site
544404005164	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
544404005165	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
544404005166	dimer interface [polypeptide binding]; other site
544404005167	PYR/PP interface [polypeptide binding]; other site
544404005168	TPP binding site [chemical binding]; other site
544404005169	substrate binding site [chemical binding]; other site
544404005170	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
544404005171	Domain of unknown function; Region: EKR; smart00890
544404005172	4Fe-4S binding domain; Region: Fer4_6; pfam12837
544404005173	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404005174	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
544404005175	TPP-binding site [chemical binding]; other site
544404005176	dimer interface [polypeptide binding]; other site
544404005177	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
544404005178	Domain of unknown function (DUF333); Region: DUF333; pfam03891
544404005179	heat-inducible protein; Provisional; Region: PRK10449
544404005180	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
544404005181	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
544404005182	putative ligand binding site [chemical binding]; other site
544404005183	putative NAD binding site [chemical binding]; other site
544404005184	catalytic site [active]
544404005185	hypothetical protein; Provisional; Region: PRK10695
544404005186	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
544404005187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
544404005188	baseplate hub subunit and tail lysozyme; Provisional; Region: 5; PHA02596
544404005189	Autotransporter beta-domain; Region: Autotransporter; pfam03797
544404005190	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404005191	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404005192	active site
544404005193	catalytic tetrad [active]
544404005194	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
544404005195	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
544404005196	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
544404005197	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
544404005198	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
544404005199	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
544404005200	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
544404005201	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404005202	S-adenosylmethionine binding site [chemical binding]; other site
544404005203	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
544404005204	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
544404005205	active site
544404005206	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
544404005207	active site
544404005208	catalytic residues [active]
544404005209	azoreductase; Reviewed; Region: PRK00170
544404005210	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
544404005211	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
544404005212	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404005213	ATP binding site [chemical binding]; other site
544404005214	putative Mg++ binding site [ion binding]; other site
544404005215	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404005216	nucleotide binding region [chemical binding]; other site
544404005217	ATP-binding site [chemical binding]; other site
544404005218	Helicase associated domain (HA2); Region: HA2; pfam04408
544404005219	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
544404005220	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
544404005221	Uncharacterized conserved protein [Function unknown]; Region: COG1434
544404005222	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
544404005223	putative active site [active]
544404005224	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
544404005225	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
544404005226	NAD binding site [chemical binding]; other site
544404005227	catalytic residues [active]
544404005228	substrate binding site [chemical binding]; other site
544404005229	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
544404005230	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
544404005231	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
544404005232	cytochrome b561; Provisional; Region: PRK11513
544404005233	hypothetical protein; Provisional; Region: PRK10040
544404005234	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
544404005235	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
544404005236	dimer interface [polypeptide binding]; other site
544404005237	ligand binding site [chemical binding]; other site
544404005238	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404005239	dimerization interface [polypeptide binding]; other site
544404005240	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
544404005241	dimer interface [polypeptide binding]; other site
544404005242	putative CheW interface [polypeptide binding]; other site
544404005243	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
544404005244	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404005245	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404005246	dimerization interface [polypeptide binding]; other site
544404005247	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
544404005248	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
544404005249	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
544404005250	hypothetical protein; Provisional; Region: PRK11415
544404005251	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
544404005252	putative trimer interface [polypeptide binding]; other site
544404005253	putative CoA binding site [chemical binding]; other site
544404005254	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
544404005255	putative trimer interface [polypeptide binding]; other site
544404005256	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
544404005257	putative CoA binding site [chemical binding]; other site
544404005258	putative trimer interface [polypeptide binding]; other site
544404005259	putative CoA binding site [chemical binding]; other site
544404005260	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
544404005261	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
544404005262	gating phenylalanine in ion channel; other site
544404005263	tellurite resistance protein TehB; Provisional; Region: PRK11207
544404005264	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404005265	S-adenosylmethionine binding site [chemical binding]; other site
544404005266	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
544404005267	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
544404005268	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404005269	non-specific DNA binding site [nucleotide binding]; other site
544404005270	salt bridge; other site
544404005271	sequence-specific DNA binding site [nucleotide binding]; other site
544404005272	Cupin domain; Region: Cupin_2; pfam07883
544404005273	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
544404005274	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
544404005275	Peptidase family U32; Region: Peptidase_U32; pfam01136
544404005276	Collagenase; Region: DUF3656; pfam12392
544404005277	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
544404005278	YcfA-like protein; Region: YcfA; pfam07927
544404005279	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
544404005280	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404005281	sequence-specific DNA binding site [nucleotide binding]; other site
544404005282	salt bridge; other site
544404005283	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
544404005284	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404005285	DNA-binding site [nucleotide binding]; DNA binding site
544404005286	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404005287	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404005288	homodimer interface [polypeptide binding]; other site
544404005289	catalytic residue [active]
544404005290	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
544404005291	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
544404005292	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
544404005293	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404005294	Walker A/P-loop; other site
544404005295	ATP binding site [chemical binding]; other site
544404005296	Q-loop/lid; other site
544404005297	ABC transporter signature motif; other site
544404005298	Walker B; other site
544404005299	D-loop; other site
544404005300	H-loop/switch region; other site
544404005301	TOBE domain; Region: TOBE_2; pfam08402
544404005302	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404005303	dimer interface [polypeptide binding]; other site
544404005304	conserved gate region; other site
544404005305	putative PBP binding loops; other site
544404005306	ABC-ATPase subunit interface; other site
544404005307	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
544404005308	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404005309	ABC-ATPase subunit interface; other site
544404005310	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
544404005311	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
544404005312	tetrameric interface [polypeptide binding]; other site
544404005313	NAD binding site [chemical binding]; other site
544404005314	catalytic residues [active]
544404005315	substrate binding site [chemical binding]; other site
544404005316	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
544404005317	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
544404005318	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
544404005319	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
544404005320	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
544404005321	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
544404005322	Prostaglandin dehydrogenases; Region: PGDH; cd05288
544404005323	NAD(P) binding site [chemical binding]; other site
544404005324	substrate binding site [chemical binding]; other site
544404005325	dimer interface [polypeptide binding]; other site
544404005326	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
544404005327	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404005328	DNA-binding site [nucleotide binding]; DNA binding site
544404005329	FCD domain; Region: FCD; pfam07729
544404005330	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
544404005331	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404005332	N-terminal plug; other site
544404005333	ligand-binding site [chemical binding]; other site
544404005334	PQQ-like domain; Region: PQQ_2; pfam13360
544404005335	L-asparagine permease; Provisional; Region: PRK15049
544404005336	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
544404005337	C-terminal domain interface [polypeptide binding]; other site
544404005338	GSH binding site (G-site) [chemical binding]; other site
544404005339	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
544404005340	dimer interface [polypeptide binding]; other site
544404005341	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
544404005342	dimer interface [polypeptide binding]; other site
544404005343	N-terminal domain interface [polypeptide binding]; other site
544404005344	substrate binding pocket (H-site) [chemical binding]; other site
544404005345	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
544404005346	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
544404005347	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
544404005348	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
544404005349	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404005350	RHS protein; Region: RHS; pfam03527
544404005351	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404005352	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
544404005353	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
544404005354	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404005355	Transposase [DNA replication, recombination, and repair]; Region: COG5433
544404005356	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
544404005357	active site 1 [active]
544404005358	dimer interface [polypeptide binding]; other site
544404005359	hexamer interface [polypeptide binding]; other site
544404005360	active site 2 [active]
544404005361	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
544404005362	hypothetical protein; Provisional; Region: PRK10281
544404005363	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
544404005364	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
544404005365	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
544404005366	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
544404005367	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
544404005368	[4Fe-4S] binding site [ion binding]; other site
544404005369	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404005370	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404005371	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404005372	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
544404005373	molybdopterin cofactor binding site; other site
544404005374	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
544404005375	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
544404005376	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
544404005377	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
544404005378	trimer interface [polypeptide binding]; other site
544404005379	eyelet of channel; other site
544404005380	aromatic amino acid exporter; Provisional; Region: PRK11689
544404005381	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
544404005382	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
544404005383	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
544404005384	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
544404005385	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
544404005386	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404005387	non-specific DNA binding site [nucleotide binding]; other site
544404005388	salt bridge; other site
544404005389	sequence-specific DNA binding site [nucleotide binding]; other site
544404005390	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
544404005391	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
544404005392	NAD binding site [chemical binding]; other site
544404005393	substrate binding site [chemical binding]; other site
544404005394	catalytic Zn binding site [ion binding]; other site
544404005395	tetramer interface [polypeptide binding]; other site
544404005396	structural Zn binding site [ion binding]; other site
544404005397	malate dehydrogenase; Provisional; Region: PRK13529
544404005398	Malic enzyme, N-terminal domain; Region: malic; pfam00390
544404005399	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
544404005400	NAD(P) binding site [chemical binding]; other site
544404005401	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
544404005402	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
544404005403	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
544404005404	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
544404005405	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404005406	Walker A/P-loop; other site
544404005407	ATP binding site [chemical binding]; other site
544404005408	Q-loop/lid; other site
544404005409	ABC transporter signature motif; other site
544404005410	Walker B; other site
544404005411	D-loop; other site
544404005412	H-loop/switch region; other site
544404005413	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
544404005414	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
544404005415	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404005416	Walker A/P-loop; other site
544404005417	ATP binding site [chemical binding]; other site
544404005418	Q-loop/lid; other site
544404005419	ABC transporter signature motif; other site
544404005420	Walker B; other site
544404005421	D-loop; other site
544404005422	H-loop/switch region; other site
544404005423	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
544404005424	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
544404005425	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
544404005426	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404005427	dimer interface [polypeptide binding]; other site
544404005428	conserved gate region; other site
544404005429	putative PBP binding loops; other site
544404005430	ABC-ATPase subunit interface; other site
544404005431	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
544404005432	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404005433	dimer interface [polypeptide binding]; other site
544404005434	conserved gate region; other site
544404005435	putative PBP binding loops; other site
544404005436	ABC-ATPase subunit interface; other site
544404005437	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
544404005438	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
544404005439	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
544404005440	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
544404005441	heme-binding site [chemical binding]; other site
544404005442	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404005443	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404005444	metal binding site [ion binding]; metal-binding site
544404005445	active site
544404005446	I-site; other site
544404005447	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
544404005448	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
544404005449	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
544404005450	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
544404005451	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404005452	catalytic residue [active]
544404005453	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
544404005454	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
544404005455	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
544404005456	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
544404005457	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
544404005458	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
544404005459	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
544404005460	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
544404005461	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
544404005462	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
544404005463	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
544404005464	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404005465	FeS/SAM binding site; other site
544404005466	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
544404005467	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
544404005468	Sulfatase; Region: Sulfatase; pfam00884
544404005469	transcriptional regulator YdeO; Provisional; Region: PRK09940
544404005470	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404005471	putative oxidoreductase; Provisional; Region: PRK09939
544404005472	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
544404005473	putative molybdopterin cofactor binding site [chemical binding]; other site
544404005474	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
544404005475	putative molybdopterin cofactor binding site; other site
544404005476	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
544404005477	mannosyl binding site [chemical binding]; other site
544404005478	Fimbrial protein; Region: Fimbrial; pfam00419
544404005479	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404005480	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404005481	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
544404005482	PapC N-terminal domain; Region: PapC_N; pfam13954
544404005483	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404005484	PapC C-terminal domain; Region: PapC_C; pfam13953
544404005485	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
544404005486	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404005487	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404005488	Fimbrial protein; Region: Fimbrial; cl01416
544404005489	Helix-turn-helix domain; Region: HTH_18; pfam12833
544404005490	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404005491	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
544404005492	HipA-like N-terminal domain; Region: HipA_N; pfam07805
544404005493	HipA-like C-terminal domain; Region: HipA_C; pfam07804
544404005494	putative lipoprotein; Provisional; Region: PRK09707
544404005495	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
544404005496	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
544404005497	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
544404005498	putative N- and C-terminal domain interface [polypeptide binding]; other site
544404005499	putative active site [active]
544404005500	putative MgATP binding site [chemical binding]; other site
544404005501	catalytic site [active]
544404005502	metal binding site [ion binding]; metal-binding site
544404005503	putative carbohydrate binding site [chemical binding]; other site
544404005504	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
544404005505	transcriptional regulator LsrR; Provisional; Region: PRK15418
544404005506	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
544404005507	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
544404005508	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
544404005509	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404005510	Walker A/P-loop; other site
544404005511	ATP binding site [chemical binding]; other site
544404005512	Q-loop/lid; other site
544404005513	ABC transporter signature motif; other site
544404005514	Walker B; other site
544404005515	D-loop; other site
544404005516	H-loop/switch region; other site
544404005517	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404005518	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404005519	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404005520	TM-ABC transporter signature motif; other site
544404005521	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404005522	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404005523	TM-ABC transporter signature motif; other site
544404005524	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
544404005525	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
544404005526	ligand binding site [chemical binding]; other site
544404005527	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
544404005528	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
544404005529	putative active site; other site
544404005530	catalytic residue [active]
544404005531	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
544404005532	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
544404005533	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404005534	S-adenosylmethionine binding site [chemical binding]; other site
544404005535	Predicted membrane protein [Function unknown]; Region: COG3781
544404005536	altronate oxidoreductase; Provisional; Region: PRK03643
544404005537	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
544404005538	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
544404005539	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404005540	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404005541	metal binding site [ion binding]; metal-binding site
544404005542	active site
544404005543	I-site; other site
544404005544	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
544404005545	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
544404005546	glutaminase; Provisional; Region: PRK00971
544404005547	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
544404005548	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
544404005549	NAD(P) binding site [chemical binding]; other site
544404005550	catalytic residues [active]
544404005551	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404005552	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404005553	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
544404005554	putative dimerization interface [polypeptide binding]; other site
544404005555	putative arabinose transporter; Provisional; Region: PRK03545
544404005556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404005557	putative substrate translocation pore; other site
544404005558	inner membrane protein; Provisional; Region: PRK10995
544404005559	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
544404005560	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
544404005561	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
544404005562	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404005563	hypothetical protein; Provisional; Region: PRK10106
544404005564	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
544404005565	EamA-like transporter family; Region: EamA; pfam00892
544404005566	EamA-like transporter family; Region: EamA; pfam00892
544404005567	putative transporter; Provisional; Region: PRK10054
544404005568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404005569	putative substrate translocation pore; other site
544404005570	Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521
544404005571	active site residue [active]
544404005572	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
544404005573	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
544404005574	conserved cys residue [active]
544404005575	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404005576	diguanylate cyclase; Provisional; Region: PRK09894
544404005577	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
544404005578	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404005579	metal binding site [ion binding]; metal-binding site
544404005580	active site
544404005581	I-site; other site
544404005582	hypothetical protein; Provisional; Region: PRK10053
544404005583	hypothetical protein; Validated; Region: PRK03657
544404005584	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
544404005585	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
544404005586	active site
544404005587	Zn binding site [ion binding]; other site
544404005588	malonic semialdehyde reductase; Provisional; Region: PRK10538
544404005589	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
544404005590	putative NAD(P) binding site [chemical binding]; other site
544404005591	homodimer interface [polypeptide binding]; other site
544404005592	homotetramer interface [polypeptide binding]; other site
544404005593	active site
544404005594	Transcriptional regulators [Transcription]; Region: GntR; COG1802
544404005595	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404005596	DNA-binding site [nucleotide binding]; DNA binding site
544404005597	FCD domain; Region: FCD; pfam07729
544404005598	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
544404005599	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
544404005600	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
544404005601	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
544404005602	metabolite-proton symporter; Region: 2A0106; TIGR00883
544404005603	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404005604	putative substrate translocation pore; other site
544404005605	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404005606	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404005607	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404005608	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404005609	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404005610	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404005611	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404005612	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404005613	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404005614	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
544404005615	Interdomain contacts; other site
544404005616	Cytokine receptor motif; other site
544404005617	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404005618	Fibronectin type III protein; Region: DUF3672; pfam12421
544404005619	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404005620	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404005621	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404005622	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404005623	MPN+ (JAMM) motif; other site
544404005624	Zinc-binding site [ion binding]; other site
544404005625	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404005626	NlpC/P60 family; Region: NLPC_P60; cl17555
544404005627	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404005628	Phage-related protein [Function unknown]; Region: COG4718
544404005629	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404005630	tape measure domain; Region: tape_meas_nterm; TIGR02675
544404005631	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
544404005632	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404005633	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
544404005634	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
544404005635	Immunoglobulin I-set domain; Region: I-set; pfam07679
544404005636	Immunoglobulin domain; Region: Ig_2; pfam13895
544404005637	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
544404005638	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
544404005639	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
544404005640	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
544404005641	oligomerization interface [polypeptide binding]; other site
544404005642	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
544404005643	Phage-related protein [Function unknown]; Region: COG4695
544404005644	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
544404005645	Phage capsid family; Region: Phage_capsid; pfam05065
544404005646	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
544404005647	Lysis protein S; Region: Lysis_S; pfam04971
544404005648	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404005649	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404005650	Tellurite resistance protein [Inorganic ion transport and metabolism]; Region: TerB; COG3793
544404005651	tellurite resistance protein terB; Region: terB; cd07176
544404005652	putative metal binding site [ion binding]; other site
544404005653	transcriptional regulator YdeO; Provisional; Region: PRK09940
544404005654	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404005655	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
544404005656	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
544404005657	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404005658	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
544404005659	Protein of unknown function (DUF551); Region: DUF551; pfam04448
544404005660	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404005661	primosomal protein DnaI; Provisional; Region: PRK02854
544404005662	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404005663	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
544404005664	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404005665	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
544404005666	non-specific DNA binding site [nucleotide binding]; other site
544404005667	salt bridge; other site
544404005668	sequence-specific DNA binding site [nucleotide binding]; other site
544404005669	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404005670	Catalytic site [active]
544404005671	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
544404005672	DicB protein; Region: DicB; pfam05358
544404005673	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
544404005674	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404005675	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404005676	DNA binding site [nucleotide binding]
544404005677	active site
544404005678	Int/Topo IB signature motif; other site
544404005679	DinI-like family; Region: DinI; pfam06183
544404005680	Transposase; Region: HTH_Tnp_1; pfam01527
544404005681	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404005682	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404005683	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404005684	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404005685	homodimer interface [polypeptide binding]; other site
544404005686	putative GKAP docking site [polypeptide binding]; other site
544404005687	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404005688	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404005689	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404005690	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404005691	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404005692	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
544404005693	Protein of unknown function (DUF433); Region: DUF433; cl01030
544404005694	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404005695	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404005696	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404005697	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404005698	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404005699	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404005700	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404005701	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404005702	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404005703	Fibronectin type III protein; Region: DUF3672; pfam12421
544404005704	Phage minor tail protein L; Region: Phage_tail_L; cl01908
544404005705	Phage-related protein [Function unknown]; Region: COG4718
544404005706	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404005707	tape measure domain; Region: tape_meas_nterm; TIGR02675
544404005708	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
544404005709	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404005710	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
544404005711	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
544404005712	Immunoglobulin domain; Region: Ig_3; pfam13927
544404005713	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
544404005714	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
544404005715	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
544404005716	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
544404005717	zinc binding site [ion binding]; other site
544404005718	Phage-related protein [Function unknown]; Region: COG4695
544404005719	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
544404005720	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
544404005721	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
544404005722	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
544404005723	Phage capsid family; Region: Phage_capsid; pfam05065
544404005724	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
544404005725	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
544404005726	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
544404005727	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
544404005728	active site
544404005729	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404005730	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
544404005731	ORF11CD3 domain; Region: ORF11CD3; pfam10549
544404005732	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404005733	catalytic residues [active]
544404005734	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
544404005735	Lysis protein S; Region: Lysis_S; pfam04971
544404005736	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404005737	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404005738	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
544404005739	tellurite resistance protein terB; Region: terB; cd07176
544404005740	putative metal binding site [ion binding]; other site
544404005741	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
544404005742	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
544404005743	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404005744	Hok/gef family; Region: HOK_GEF; pfam01848
544404005745	Protein of unknown function (DUF551); Region: DUF551; pfam04448
544404005746	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
544404005747	putative replication protein; Provisional; Region: PRK12377
544404005748	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404005749	Walker A motif; other site
544404005750	ATP binding site [chemical binding]; other site
544404005751	Walker B motif; other site
544404005752	Helix-turn-helix domain; Region: HTH_36; pfam13730
544404005753	primosomal protein DnaI; Provisional; Region: PRK02854
544404005754	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404005755	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
544404005756	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404005757	sequence-specific DNA binding site [nucleotide binding]; other site
544404005758	salt bridge; other site
544404005759	transcriptional repressor DicA; Reviewed; Region: PRK09706
544404005760	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
544404005761	DicB protein; Region: DicB; pfam05358
544404005762	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
544404005763	exonuclease VIII; Reviewed; Region: PRK09709
544404005764	Transposase; Region: HTH_Tnp_1; cl17663
544404005765	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404005766	putative transposase OrfB; Reviewed; Region: PHA02517
544404005767	HTH-like domain; Region: HTH_21; pfam13276
544404005768	Integrase core domain; Region: rve; pfam00665
544404005769	Integrase core domain; Region: rve_3; pfam13683
544404005770	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404005771	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
544404005772	active site
544404005773	catalytic site [active]
544404005774	substrate binding site [chemical binding]; other site
544404005775	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
544404005776	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404005777	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404005778	hypothetical protein; Provisional; Region: PRK02237
544404005779	hypothetical protein; Provisional; Region: PRK13659
544404005780	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
544404005781	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404005782	Coenzyme A binding pocket [chemical binding]; other site
544404005783	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
544404005784	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
544404005785	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
544404005786	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
544404005787	putative [Fe4-S4] binding site [ion binding]; other site
544404005788	putative molybdopterin cofactor binding site [chemical binding]; other site
544404005789	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
544404005790	putative molybdopterin cofactor binding site; other site
544404005791	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
544404005792	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
544404005793	putative [Fe4-S4] binding site [ion binding]; other site
544404005794	putative molybdopterin cofactor binding site [chemical binding]; other site
544404005795	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
544404005796	putative molybdopterin cofactor binding site; other site
544404005797	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
544404005798	4Fe-4S binding domain; Region: Fer4; cl02805
544404005799	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
544404005800	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
544404005801	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
544404005802	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
544404005803	Cl- selectivity filter; other site
544404005804	Cl- binding residues [ion binding]; other site
544404005805	pore gating glutamate residue; other site
544404005806	dimer interface [polypeptide binding]; other site
544404005807	putative dithiobiotin synthetase; Provisional; Region: PRK12374
544404005808	AAA domain; Region: AAA_26; pfam13500
544404005809	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
544404005810	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
544404005811	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404005812	nucleotide binding site [chemical binding]; other site
544404005813	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
544404005814	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404005815	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
544404005816	dimerization interface [polypeptide binding]; other site
544404005817	substrate binding pocket [chemical binding]; other site
544404005818	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
544404005819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404005820	putative substrate translocation pore; other site
544404005821	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
544404005822	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
544404005823	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
544404005824	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
544404005825	Domain of unknown function DUF20; Region: UPF0118; pfam01594
544404005826	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
544404005827	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
544404005828	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
544404005829	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
544404005830	ligand binding site [chemical binding]; other site
544404005831	homodimer interface [polypeptide binding]; other site
544404005832	NAD(P) binding site [chemical binding]; other site
544404005833	trimer interface B [polypeptide binding]; other site
544404005834	trimer interface A [polypeptide binding]; other site
544404005835	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
544404005836	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404005837	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404005838	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404005839	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
544404005840	Spore germination protein; Region: Spore_permease; cl17796
544404005841	dihydromonapterin reductase; Provisional; Region: PRK06483
544404005842	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
544404005843	NADP binding site [chemical binding]; other site
544404005844	substrate binding pocket [chemical binding]; other site
544404005845	active site
544404005846	GlpM protein; Region: GlpM; pfam06942
544404005847	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
544404005848	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404005849	active site
544404005850	phosphorylation site [posttranslational modification]
544404005851	intermolecular recognition site; other site
544404005852	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404005853	DNA binding site [nucleotide binding]
544404005854	sensor protein RstB; Provisional; Region: PRK10604
544404005855	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404005856	dimerization interface [polypeptide binding]; other site
544404005857	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404005858	dimer interface [polypeptide binding]; other site
544404005859	phosphorylation site [posttranslational modification]
544404005860	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404005861	ATP binding site [chemical binding]; other site
544404005862	Mg2+ binding site [ion binding]; other site
544404005863	G-X-G motif; other site
544404005864	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
544404005865	fumarate hydratase; Reviewed; Region: fumC; PRK00485
544404005866	Class II fumarases; Region: Fumarase_classII; cd01362
544404005867	active site
544404005868	tetramer interface [polypeptide binding]; other site
544404005869	fumarate hydratase; Provisional; Region: PRK15389
544404005870	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
544404005871	Fumarase C-terminus; Region: Fumerase_C; pfam05683
544404005872	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
544404005873	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
544404005874	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
544404005875	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
544404005876	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
544404005877	putative outer membrane porin protein; Provisional; Region: PRK11379
544404005878	glucuronide transporter; Provisional; Region: PRK09848
544404005879	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
544404005880	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
544404005881	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404005882	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
544404005883	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
544404005884	NAD binding site [chemical binding]; other site
544404005885	substrate binding site [chemical binding]; other site
544404005886	homotetramer interface [polypeptide binding]; other site
544404005887	homodimer interface [polypeptide binding]; other site
544404005888	active site
544404005889	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
544404005890	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404005891	DNA binding site [nucleotide binding]
544404005892	domain linker motif; other site
544404005893	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
544404005894	putative dimerization interface [polypeptide binding]; other site
544404005895	putative ligand binding site [chemical binding]; other site
544404005896	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
544404005897	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
544404005898	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404005899	active site turn [active]
544404005900	phosphorylation site [posttranslational modification]
544404005901	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
544404005902	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404005903	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404005904	homodimer interface [polypeptide binding]; other site
544404005905	catalytic residue [active]
544404005906	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
544404005907	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
544404005908	active site
544404005909	purine riboside binding site [chemical binding]; other site
544404005910	putative oxidoreductase; Provisional; Region: PRK11579
544404005911	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
544404005912	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
544404005913	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
544404005914	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
544404005915	electron transport complex protein RsxA; Provisional; Region: PRK05151
544404005916	electron transport complex protein RnfB; Provisional; Region: PRK05113
544404005917	Putative Fe-S cluster; Region: FeS; pfam04060
544404005918	4Fe-4S binding domain; Region: Fer4; pfam00037
544404005919	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
544404005920	SLBB domain; Region: SLBB; pfam10531
544404005921	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404005922	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
544404005923	electron transport complex protein RnfG; Validated; Region: PRK01908
544404005924	electron transport complex RsxE subunit; Provisional; Region: PRK12405
544404005925	endonuclease III; Provisional; Region: PRK10702
544404005926	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
544404005927	minor groove reading motif; other site
544404005928	helix-hairpin-helix signature motif; other site
544404005929	substrate binding pocket [chemical binding]; other site
544404005930	active site
544404005931	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
544404005932	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
544404005933	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404005934	putative substrate translocation pore; other site
544404005935	POT family; Region: PTR2; pfam00854
544404005936	glutathionine S-transferase; Provisional; Region: PRK10542
544404005937	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
544404005938	C-terminal domain interface [polypeptide binding]; other site
544404005939	GSH binding site (G-site) [chemical binding]; other site
544404005940	dimer interface [polypeptide binding]; other site
544404005941	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
544404005942	N-terminal domain interface [polypeptide binding]; other site
544404005943	dimer interface [polypeptide binding]; other site
544404005944	substrate binding pocket (H-site) [chemical binding]; other site
544404005945	pyridoxamine kinase; Validated; Region: PRK05756
544404005946	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
544404005947	dimer interface [polypeptide binding]; other site
544404005948	pyridoxal binding site [chemical binding]; other site
544404005949	ATP binding site [chemical binding]; other site
544404005950	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
544404005951	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
544404005952	active site
544404005953	HIGH motif; other site
544404005954	dimer interface [polypeptide binding]; other site
544404005955	KMSKS motif; other site
544404005956	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404005957	RNA binding surface [nucleotide binding]; other site
544404005958	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
544404005959	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
544404005960	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
544404005961	lysozyme inhibitor; Provisional; Region: PRK11372
544404005962	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
544404005963	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
544404005964	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
544404005965	transcriptional regulator SlyA; Provisional; Region: PRK03573
544404005966	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
544404005967	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
544404005968	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
544404005969	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404005970	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404005971	Fusaric acid resistance protein family; Region: FUSC; pfam04632
544404005972	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
544404005973	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
544404005974	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
544404005975	E-class dimer interface [polypeptide binding]; other site
544404005976	P-class dimer interface [polypeptide binding]; other site
544404005977	active site
544404005978	Cu2+ binding site [ion binding]; other site
544404005979	Zn2+ binding site [ion binding]; other site
544404005980	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404005981	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404005982	active site
544404005983	catalytic tetrad [active]
544404005984	Predicted Fe-S protein [General function prediction only]; Region: COG3313
544404005985	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
544404005986	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404005987	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
544404005988	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
544404005989	FMN binding site [chemical binding]; other site
544404005990	active site
544404005991	substrate binding site [chemical binding]; other site
544404005992	catalytic residue [active]
544404005993	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
544404005994	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
544404005995	dimer interface [polypeptide binding]; other site
544404005996	active site
544404005997	metal binding site [ion binding]; metal-binding site
544404005998	glutathione binding site [chemical binding]; other site
544404005999	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
544404006000	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
544404006001	dimer interface [polypeptide binding]; other site
544404006002	catalytic site [active]
544404006003	putative active site [active]
544404006004	putative substrate binding site [chemical binding]; other site
544404006005	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404006006	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
544404006007	ATP binding site [chemical binding]; other site
544404006008	putative Mg++ binding site [ion binding]; other site
544404006009	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404006010	nucleotide binding region [chemical binding]; other site
544404006011	ATP-binding site [chemical binding]; other site
544404006012	DEAD/H associated; Region: DEAD_assoc; pfam08494
544404006013	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
544404006014	putative GSH binding site [chemical binding]; other site
544404006015	catalytic residues [active]
544404006016	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404006017	NlpC/P60 family; Region: NLPC_P60; pfam00877
544404006018	superoxide dismutase; Provisional; Region: PRK10543
544404006019	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
544404006020	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
544404006021	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006022	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404006023	putative substrate translocation pore; other site
544404006024	hypothetical protein; Provisional; Region: PRK14756
544404006025	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
544404006026	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404006027	DNA binding site [nucleotide binding]
544404006028	domain linker motif; other site
544404006029	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
544404006030	dimerization interface [polypeptide binding]; other site
544404006031	ligand binding site [chemical binding]; other site
544404006032	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
544404006033	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404006034	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404006035	dimerization interface [polypeptide binding]; other site
544404006036	putative transporter; Provisional; Region: PRK11043
544404006037	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006038	putative substrate translocation pore; other site
544404006039	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
544404006040	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
544404006041	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404006042	S-adenosylmethionine binding site [chemical binding]; other site
544404006043	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
544404006044	Lumazine binding domain; Region: Lum_binding; pfam00677
544404006045	Lumazine binding domain; Region: Lum_binding; pfam00677
544404006046	multidrug efflux protein; Reviewed; Region: PRK01766
544404006047	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
544404006048	cation binding site [ion binding]; other site
544404006049	hypothetical protein; Provisional; Region: PRK09945
544404006050	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
544404006051	putative monooxygenase; Provisional; Region: PRK11118
544404006052	hypothetical protein; Provisional; Region: PRK09897
544404006053	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
544404006054	hypothetical protein; Provisional; Region: PRK09946
544404006055	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
544404006056	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
544404006057	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
544404006058	hypothetical protein; Provisional; Region: PRK09947
544404006059	putative oxidoreductase; Provisional; Region: PRK09849
544404006060	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
544404006061	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
544404006062	hypothetical protein; Provisional; Region: PRK09898
544404006063	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404006064	hypothetical protein; Provisional; Region: PRK10292
544404006065	pyruvate kinase; Provisional; Region: PRK09206
544404006066	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
544404006067	domain interfaces; other site
544404006068	active site
544404006069	murein lipoprotein; Provisional; Region: PRK15396
544404006070	L,D-transpeptidase; Provisional; Region: PRK10190
544404006071	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404006072	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404006073	cysteine desufuration protein SufE; Provisional; Region: PRK09296
544404006074	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
544404006075	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
544404006076	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
544404006077	catalytic residue [active]
544404006078	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
544404006079	FeS assembly protein SufD; Region: sufD; TIGR01981
544404006080	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
544404006081	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
544404006082	Walker A/P-loop; other site
544404006083	ATP binding site [chemical binding]; other site
544404006084	Q-loop/lid; other site
544404006085	ABC transporter signature motif; other site
544404006086	Walker B; other site
544404006087	D-loop; other site
544404006088	H-loop/switch region; other site
544404006089	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
544404006090	putative ABC transporter; Region: ycf24; CHL00085
544404006091	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
544404006092	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
544404006093	CoenzymeA binding site [chemical binding]; other site
544404006094	subunit interaction site [polypeptide binding]; other site
544404006095	PHB binding site; other site
544404006096	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
544404006097	FAD binding domain; Region: FAD_binding_4; pfam01565
544404006098	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
544404006099	putative inner membrane protein; Provisional; Region: PRK10983
544404006100	Domain of unknown function DUF20; Region: UPF0118; pfam01594
544404006101	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
544404006102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006103	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404006104	putative substrate translocation pore; other site
544404006105	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006106	putative substrate translocation pore; other site
544404006107	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
544404006108	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
544404006109	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
544404006110	shikimate binding site; other site
544404006111	NAD(P) binding site [chemical binding]; other site
544404006112	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
544404006113	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
544404006114	active site
544404006115	catalytic residue [active]
544404006116	dimer interface [polypeptide binding]; other site
544404006117	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
544404006118	Coenzyme A transferase; Region: CoA_trans; smart00882
544404006119	Coenzyme A transferase; Region: CoA_trans; cl17247
544404006120	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
544404006121	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
544404006122	active site
544404006123	Cupin domain; Region: Cupin_2; pfam07883
544404006124	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
544404006125	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404006126	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404006127	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
544404006128	Ligand binding site [chemical binding]; other site
544404006129	Electron transfer flavoprotein domain; Region: ETF; pfam01012
544404006130	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
544404006131	Electron transfer flavoprotein domain; Region: ETF; smart00893
544404006132	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
544404006133	oxidoreductase; Provisional; Region: PRK10015
544404006134	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
544404006135	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
544404006136	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
544404006137	acyl-activating enzyme (AAE) consensus motif; other site
544404006138	putative active site [active]
544404006139	putative AMP binding site [chemical binding]; other site
544404006140	putative CoA binding site [chemical binding]; other site
544404006141	phosphoenolpyruvate synthase; Validated; Region: PRK06464
544404006142	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
544404006143	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
544404006144	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
544404006145	PEP synthetase regulatory protein; Provisional; Region: PRK05339
544404006146	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
544404006147	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
544404006148	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
544404006149	Uncharacterized conserved protein [Function unknown]; Region: COG0397
544404006150	hypothetical protein; Validated; Region: PRK00029
544404006151	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
544404006152	NlpC/P60 family; Region: NLPC_P60; pfam00877
544404006153	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
544404006154	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
544404006155	Walker A/P-loop; other site
544404006156	ATP binding site [chemical binding]; other site
544404006157	Q-loop/lid; other site
544404006158	ABC transporter signature motif; other site
544404006159	Walker B; other site
544404006160	D-loop; other site
544404006161	H-loop/switch region; other site
544404006162	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
544404006163	catalytic residues [active]
544404006164	dimer interface [polypeptide binding]; other site
544404006165	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
544404006166	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404006167	ABC-ATPase subunit  interface; other site
544404006168	dimer interface [polypeptide binding]; other site
544404006169	putative PBP binding regions; other site
544404006170	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
544404006171	IHF dimer interface [polypeptide binding]; other site
544404006172	IHF - DNA interface [nucleotide binding]; other site
544404006173	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
544404006174	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
544404006175	putative tRNA-binding site [nucleotide binding]; other site
544404006176	B3/4 domain; Region: B3_4; pfam03483
544404006177	tRNA synthetase B5 domain; Region: B5; smart00874
544404006178	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
544404006179	dimer interface [polypeptide binding]; other site
544404006180	motif 1; other site
544404006181	motif 3; other site
544404006182	motif 2; other site
544404006183	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
544404006184	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
544404006185	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
544404006186	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
544404006187	dimer interface [polypeptide binding]; other site
544404006188	motif 1; other site
544404006189	active site
544404006190	motif 2; other site
544404006191	motif 3; other site
544404006192	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
544404006193	23S rRNA binding site [nucleotide binding]; other site
544404006194	L21 binding site [polypeptide binding]; other site
544404006195	L13 binding site [polypeptide binding]; other site
544404006196	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
544404006197	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
544404006198	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
544404006199	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
544404006200	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
544404006201	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
544404006202	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
544404006203	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
544404006204	active site
544404006205	dimer interface [polypeptide binding]; other site
544404006206	motif 1; other site
544404006207	motif 2; other site
544404006208	motif 3; other site
544404006209	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
544404006210	anticodon binding site; other site
544404006211	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
544404006212	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
544404006213	6-phosphofructokinase 2; Provisional; Region: PRK10294
544404006214	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
544404006215	putative substrate binding site [chemical binding]; other site
544404006216	putative ATP binding site [chemical binding]; other site
544404006217	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
544404006218	Phosphotransferase enzyme family; Region: APH; pfam01636
544404006219	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
544404006220	active site
544404006221	ATP binding site [chemical binding]; other site
544404006222	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
544404006223	YniB-like protein; Region: YniB; pfam14002
544404006224	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
544404006225	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
544404006226	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404006227	motif II; other site
544404006228	inner membrane protein; Provisional; Region: PRK11648
544404006229	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
544404006230	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
544404006231	cell division modulator; Provisional; Region: PRK10113
544404006232	hydroperoxidase II; Provisional; Region: katE; PRK11249
544404006233	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
544404006234	tetramer interface [polypeptide binding]; other site
544404006235	heme binding pocket [chemical binding]; other site
544404006236	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
544404006237	domain interactions; other site
544404006238	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
544404006239	putative active site [active]
544404006240	YdjC motif; other site
544404006241	Mg binding site [ion binding]; other site
544404006242	putative homodimer interface [polypeptide binding]; other site
544404006243	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
544404006244	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
544404006245	NAD binding site [chemical binding]; other site
544404006246	sugar binding site [chemical binding]; other site
544404006247	divalent metal binding site [ion binding]; other site
544404006248	tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404006249	dimer interface [polypeptide binding]; other site
544404006250	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
544404006251	Cupin domain; Region: Cupin_2; pfam07883
544404006252	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404006253	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
544404006254	methionine cluster; other site
544404006255	active site
544404006256	phosphorylation site [posttranslational modification]
544404006257	metal binding site [ion binding]; metal-binding site
544404006258	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
544404006259	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
544404006260	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
544404006261	active site
544404006262	P-loop; other site
544404006263	phosphorylation site [posttranslational modification]
544404006264	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
544404006265	NAD+ synthetase; Region: nadE; TIGR00552
544404006266	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
544404006267	homodimer interface [polypeptide binding]; other site
544404006268	NAD binding pocket [chemical binding]; other site
544404006269	ATP binding pocket [chemical binding]; other site
544404006270	Mg binding site [ion binding]; other site
544404006271	active-site loop [active]
544404006272	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
544404006273	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
544404006274	GIY-YIG motif/motif A; other site
544404006275	active site
544404006276	catalytic site [active]
544404006277	putative DNA binding site [nucleotide binding]; other site
544404006278	metal binding site [ion binding]; metal-binding site
544404006279	hypothetical protein; Provisional; Region: PRK11396
544404006280	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
544404006281	dimer interface [polypeptide binding]; other site
544404006282	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
544404006283	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
544404006284	putative active site [active]
544404006285	Zn binding site [ion binding]; other site
544404006286	succinylarginine dihydrolase; Provisional; Region: PRK13281
544404006287	succinylglutamic semialdehyde dehydrogenase; Region: arg_catab_astD; TIGR03240
544404006288	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
544404006289	NAD(P) binding site [chemical binding]; other site
544404006290	catalytic residues [active]
544404006291	arginine succinyltransferase; Provisional; Region: PRK10456
544404006292	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
544404006293	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
544404006294	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404006295	inhibitor-cofactor binding pocket; inhibition site
544404006296	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404006297	catalytic residue [active]
544404006298	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
544404006299	putative catalytic site [active]
544404006300	putative phosphate binding site [ion binding]; other site
544404006301	active site
544404006302	metal binding site A [ion binding]; metal-binding site
544404006303	DNA binding site [nucleotide binding]
544404006304	putative AP binding site [nucleotide binding]; other site
544404006305	putative metal binding site B [ion binding]; other site
544404006306	Uncharacterized conserved protein [Function unknown]; Region: COG0398
544404006307	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
544404006308	Uncharacterized conserved protein [Function unknown]; Region: COG0398
544404006309	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
544404006310	Uncharacterized conserved protein [Function unknown]; Region: COG2128
544404006311	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
544404006312	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
544404006313	hypothetical protein; Provisional; Region: PRK11622
544404006314	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
544404006315	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404006316	dimer interface [polypeptide binding]; other site
544404006317	conserved gate region; other site
544404006318	putative PBP binding loops; other site
544404006319	ABC-ATPase subunit interface; other site
544404006320	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
544404006321	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404006322	Walker A/P-loop; other site
544404006323	ATP binding site [chemical binding]; other site
544404006324	Q-loop/lid; other site
544404006325	ABC transporter signature motif; other site
544404006326	Walker B; other site
544404006327	D-loop; other site
544404006328	H-loop/switch region; other site
544404006329	Rhodanese Homology Domain; Region: RHOD; smart00450
544404006330	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
544404006331	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
544404006332	active site residue [active]
544404006333	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
544404006334	active site residue [active]
544404006335	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
544404006336	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
544404006337	active site
544404006338	8-oxo-dGMP binding site [chemical binding]; other site
544404006339	nudix motif; other site
544404006340	metal binding site [ion binding]; metal-binding site
544404006341	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
544404006342	glutamate dehydrogenase; Provisional; Region: PRK09414
544404006343	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
544404006344	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
544404006345	NAD(P) binding site [chemical binding]; other site
544404006346	hypothetical protein; Provisional; Region: PRK11380
544404006347	DNA topoisomerase III; Provisional; Region: PRK07726
544404006348	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
544404006349	active site
544404006350	putative interdomain interaction site [polypeptide binding]; other site
544404006351	putative metal-binding site [ion binding]; other site
544404006352	putative nucleotide binding site [chemical binding]; other site
544404006353	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
544404006354	domain I; other site
544404006355	DNA binding groove [nucleotide binding]
544404006356	phosphate binding site [ion binding]; other site
544404006357	domain II; other site
544404006358	domain III; other site
544404006359	nucleotide binding site [chemical binding]; other site
544404006360	catalytic site [active]
544404006361	domain IV; other site
544404006362	selenophosphate synthetase; Provisional; Region: PRK00943
544404006363	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
544404006364	dimerization interface [polypeptide binding]; other site
544404006365	putative ATP binding site [chemical binding]; other site
544404006366	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
544404006367	putative FMN binding site [chemical binding]; other site
544404006368	protease 4; Provisional; Region: PRK10949
544404006369	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
544404006370	tandem repeat interface [polypeptide binding]; other site
544404006371	oligomer interface [polypeptide binding]; other site
544404006372	active site residues [active]
544404006373	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
544404006374	tandem repeat interface [polypeptide binding]; other site
544404006375	oligomer interface [polypeptide binding]; other site
544404006376	active site residues [active]
544404006377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2859
544404006378	Uncharacterized conserved protein [Function unknown]; Region: COG2968
544404006379	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
544404006380	active site
544404006381	homodimer interface [polypeptide binding]; other site
544404006382	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
544404006383	Isochorismatase family; Region: Isochorismatase; pfam00857
544404006384	catalytic triad [active]
544404006385	metal binding site [ion binding]; metal-binding site
544404006386	conserved cis-peptide bond; other site
544404006387	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006389	Transposase; Region: HTH_Tnp_1; cl17663
544404006390	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404006391	putative transposase OrfB; Reviewed; Region: PHA02517
544404006392	HTH-like domain; Region: HTH_21; pfam13276
544404006393	Integrase core domain; Region: rve; pfam00665
544404006394	Integrase core domain; Region: rve_3; pfam13683
544404006395	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
544404006396	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
544404006397	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404006398	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404006399	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404006400	active site
544404006401	catalytic tetrad [active]
544404006402	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404006403	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
544404006404	substrate binding site [chemical binding]; other site
544404006405	ATP binding site [chemical binding]; other site
544404006406	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
544404006407	intersubunit interface [polypeptide binding]; other site
544404006408	active site
544404006409	zinc binding site [ion binding]; other site
544404006410	Na+ binding site [ion binding]; other site
544404006411	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404006412	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
544404006413	inhibitor binding site; inhibition site
544404006414	catalytic Zn binding site [ion binding]; other site
544404006415	structural Zn binding site [ion binding]; other site
544404006416	NADP binding site [chemical binding]; other site
544404006417	tetramer interface [polypeptide binding]; other site
544404006418	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006419	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006420	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404006421	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
544404006422	putative NAD(P) binding site [chemical binding]; other site
544404006423	catalytic Zn binding site [ion binding]; other site
544404006424	structural Zn binding site [ion binding]; other site
544404006425	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
544404006426	methionine sulfoxide reductase B; Provisional; Region: PRK00222
544404006427	SelR domain; Region: SelR; pfam01641
544404006428	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
544404006429	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
544404006430	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
544404006431	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
544404006432	active site
544404006433	phosphate binding residues; other site
544404006434	catalytic residues [active]
544404006435	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404006436	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404006437	active site
544404006438	catalytic tetrad [active]
544404006439	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
544404006440	PrkA family serine protein kinase; Provisional; Region: PRK15455
544404006441	AAA ATPase domain; Region: AAA_16; pfam13191
544404006442	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
544404006443	hypothetical protein; Provisional; Region: PRK05325
544404006444	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404006445	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404006446	metal binding site [ion binding]; metal-binding site
544404006447	active site
544404006448	I-site; other site
544404006449	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404006450	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404006451	metal binding site [ion binding]; metal-binding site
544404006452	active site
544404006453	I-site; other site
544404006454	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
544404006455	putative deacylase active site [active]
544404006456	Predicted membrane protein [Function unknown]; Region: COG2707
544404006457	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404006458	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404006459	cyanate transporter; Region: CynX; TIGR00896
544404006460	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006461	Uncharacterized conserved protein [Function unknown]; Region: COG3189
544404006462	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
544404006463	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
544404006464	Domain of unknown function (DUF333); Region: DUF333; pfam03891
544404006465	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
544404006466	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
544404006467	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404006468	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404006469	metal binding site [ion binding]; metal-binding site
544404006470	active site
544404006471	I-site; other site
544404006472	hypothetical protein; Provisional; Region: PRK10457
544404006473	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
544404006474	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
544404006475	leucine export protein LeuE; Provisional; Region: PRK10958
544404006476	transcriptional activator TtdR; Provisional; Region: PRK09801
544404006477	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404006478	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
544404006479	putative effector binding pocket; other site
544404006480	putative dimerization interface [polypeptide binding]; other site
544404006481	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
544404006482	tartrate dehydrogenase; Region: TTC; TIGR02089
544404006483	putative transporter; Provisional; Region: PRK09950
544404006484	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
544404006485	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
544404006486	[2Fe-2S] cluster binding site [ion binding]; other site
544404006487	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
544404006488	putative alpha subunit interface [polypeptide binding]; other site
544404006489	putative active site [active]
544404006490	putative substrate binding site [chemical binding]; other site
544404006491	Fe binding site [ion binding]; other site
544404006492	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
544404006493	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
544404006494	FMN-binding pocket [chemical binding]; other site
544404006495	flavin binding motif; other site
544404006496	phosphate binding motif [ion binding]; other site
544404006497	beta-alpha-beta structure motif; other site
544404006498	NAD binding pocket [chemical binding]; other site
544404006499	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404006500	catalytic loop [active]
544404006501	iron binding site [ion binding]; other site
544404006502	ribonuclease D; Provisional; Region: PRK10829
544404006503	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
544404006504	catalytic site [active]
544404006505	putative active site [active]
544404006506	putative substrate binding site [chemical binding]; other site
544404006507	Helicase and RNase D C-terminal; Region: HRDC; smart00341
544404006508	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
544404006509	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
544404006510	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
544404006511	acyl-activating enzyme (AAE) consensus motif; other site
544404006512	putative AMP binding site [chemical binding]; other site
544404006513	putative active site [active]
544404006514	putative CoA binding site [chemical binding]; other site
544404006515	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
544404006516	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
544404006517	Glycoprotease family; Region: Peptidase_M22; pfam00814
544404006518	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
544404006519	DEAD/DEAH box helicase; Region: DEAD; pfam00270
544404006520	DEAD_2; Region: DEAD_2; pfam06733
544404006521	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
544404006522	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
544404006523	homotrimer interaction site [polypeptide binding]; other site
544404006524	putative active site [active]
544404006525	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
544404006526	hypothetical protein; Provisional; Region: PRK05114
544404006527	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
544404006528	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
544404006529	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
544404006530	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
544404006531	putative active site [active]
544404006532	putative CoA binding site [chemical binding]; other site
544404006533	nudix motif; other site
544404006534	metal binding site [ion binding]; metal-binding site
544404006535	L-serine deaminase; Provisional; Region: PRK15023
544404006536	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
544404006537	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
544404006538	phage resistance protein; Provisional; Region: PRK10551
544404006539	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
544404006540	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404006541	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
544404006542	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
544404006543	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
544404006544	Transporter associated domain; Region: CorC_HlyC; smart01091
544404006545	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
544404006546	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
544404006547	active pocket/dimerization site; other site
544404006548	active site
544404006549	phosphorylation site [posttranslational modification]
544404006550	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
544404006551	active site
544404006552	phosphorylation site [posttranslational modification]
544404006553	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
544404006554	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
544404006555	Predicted membrane protein [Function unknown]; Region: COG4811
544404006556	hypothetical protein; Provisional; Region: PRK11469
544404006557	Domain of unknown function DUF; Region: DUF204; pfam02659
544404006558	Domain of unknown function DUF; Region: DUF204; pfam02659
544404006559	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
544404006560	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404006561	S-adenosylmethionine binding site [chemical binding]; other site
544404006562	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
544404006563	DNA-binding site [nucleotide binding]; DNA binding site
544404006564	RNA-binding motif; other site
544404006565	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
544404006566	YebO-like protein; Region: YebO; pfam13974
544404006567	PhoPQ regulatory protein; Provisional; Region: PRK10299
544404006568	YobH-like protein; Region: YobH; pfam13996
544404006569	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
544404006570	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404006571	dimerization interface [polypeptide binding]; other site
544404006572	putative Zn2+ binding site [ion binding]; other site
544404006573	putative DNA binding site [nucleotide binding]; other site
544404006574	Bacterial transcriptional regulator; Region: IclR; pfam01614
544404006575	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404006576	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404006577	putative substrate translocation pore; other site
544404006578	Predicted integral membrane protein [Function unknown]; Region: COG5521
544404006579	heat shock protein HtpX; Provisional; Region: PRK05457
544404006580	carboxy-terminal protease; Provisional; Region: PRK11186
544404006581	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
544404006582	protein binding site [polypeptide binding]; other site
544404006583	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
544404006584	Catalytic dyad [active]
544404006585	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
544404006586	ProP expression regulator; Provisional; Region: PRK04950
544404006587	ProQ/FINO family; Region: ProQ; pfam04352
544404006588	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
544404006589	GAF domain; Region: GAF_2; pfam13185
544404006590	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
544404006591	Paraquat-inducible protein A; Region: PqiA; pfam04403
544404006592	Paraquat-inducible protein A; Region: PqiA; pfam04403
544404006593	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
544404006594	mce related protein; Region: MCE; pfam02470
544404006595	mce related protein; Region: MCE; pfam02470
544404006596	mce related protein; Region: MCE; pfam02470
544404006597	mce related protein; Region: MCE; pfam02470
544404006598	mce related protein; Region: MCE; pfam02470
544404006599	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
544404006600	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404006601	S-adenosylmethionine binding site [chemical binding]; other site
544404006602	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
544404006603	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
544404006604	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
544404006605	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
544404006606	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
544404006607	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
544404006608	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
544404006609	hypothetical protein; Provisional; Region: PRK10301
544404006610	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
544404006611	Predicted amidohydrolase [General function prediction only]; Region: COG0388
544404006612	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
544404006613	exodeoxyribonuclease X; Provisional; Region: PRK07983
544404006614	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
544404006615	active site
544404006616	catalytic site [active]
544404006617	substrate binding site [chemical binding]; other site
544404006618	protease 2; Provisional; Region: PRK10115
544404006619	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
544404006620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
544404006621	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
544404006622	putative metal binding site [ion binding]; other site
544404006623	hypothetical protein; Provisional; Region: PRK13680
544404006624	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
544404006625	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
544404006626	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
544404006627	ATP-grasp domain; Region: ATP-grasp; pfam02222
544404006628	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
544404006629	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
544404006630	active site
544404006631	intersubunit interface [polypeptide binding]; other site
544404006632	catalytic residue [active]
544404006633	phosphogluconate dehydratase; Validated; Region: PRK09054
544404006634	6-phosphogluconate dehydratase; Region: edd; TIGR01196
544404006635	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
544404006636	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
544404006637	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
544404006638	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
544404006639	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
544404006640	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
544404006641	putative active site [active]
544404006642	pyruvate kinase; Provisional; Region: PRK05826
544404006643	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
544404006644	domain interfaces; other site
544404006645	active site
544404006646	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
544404006647	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
544404006648	putative acyl-acceptor binding pocket; other site
544404006649	putative peptidase; Provisional; Region: PRK11649
544404006650	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
544404006651	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404006652	Peptidase family M23; Region: Peptidase_M23; pfam01551
544404006653	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
544404006654	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
544404006655	metal binding site [ion binding]; metal-binding site
544404006656	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
544404006657	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
544404006658	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
544404006659	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404006660	ABC-ATPase subunit  interface; other site
544404006661	dimer interface [polypeptide binding]; other site
544404006662	putative PBP binding regions; other site
544404006663	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
544404006664	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404006665	Walker A motif; other site
544404006666	ATP binding site [chemical binding]; other site
544404006667	Walker B motif; other site
544404006668	arginine finger; other site
544404006669	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
544404006670	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
544404006671	RuvA N terminal domain; Region: RuvA_N; pfam01330
544404006672	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
544404006673	hypothetical protein; Provisional; Region: PRK11470
544404006674	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
544404006675	active site
544404006676	putative DNA-binding cleft [nucleotide binding]; other site
544404006677	dimer interface [polypeptide binding]; other site
544404006678	hypothetical protein; Validated; Region: PRK00110
544404006679	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
544404006680	nudix motif; other site
544404006681	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
544404006682	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
544404006683	dimer interface [polypeptide binding]; other site
544404006684	anticodon binding site; other site
544404006685	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
544404006686	homodimer interface [polypeptide binding]; other site
544404006687	motif 1; other site
544404006688	active site
544404006689	motif 2; other site
544404006690	GAD domain; Region: GAD; pfam02938
544404006691	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
544404006692	motif 3; other site
544404006693	Isochorismatase family; Region: Isochorismatase; pfam00857
544404006694	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
544404006695	catalytic triad [active]
544404006696	conserved cis-peptide bond; other site
544404006697	hypothetical protein; Provisional; Region: PRK10302
544404006698	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
544404006699	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404006700	S-adenosylmethionine binding site [chemical binding]; other site
544404006701	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404006702	S-adenosylmethionine binding site [chemical binding]; other site
544404006703	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
544404006704	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
544404006705	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
544404006706	molybdopterin cofactor binding site [chemical binding]; other site
544404006707	substrate binding site [chemical binding]; other site
544404006708	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
544404006709	molybdopterin cofactor binding site; other site
544404006710	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
544404006711	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
544404006712	copper homeostasis protein CutC; Provisional; Region: PRK11572
544404006713	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
544404006714	putative metal binding site [ion binding]; other site
544404006715	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
544404006716	arginyl-tRNA synthetase; Region: argS; TIGR00456
544404006717	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
544404006718	active site
544404006719	HIGH motif; other site
544404006720	KMSK motif region; other site
544404006721	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
544404006722	tRNA binding surface [nucleotide binding]; other site
544404006723	anticodon binding site; other site
544404006724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
544404006725	Flagellar protein FlhE; Region: FlhE; pfam06366
544404006726	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
544404006727	FHIPEP family; Region: FHIPEP; pfam00771
544404006728	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
544404006729	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
544404006730	chemotaxis regulator CheZ; Provisional; Region: PRK11166
544404006731	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
544404006732	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404006733	active site
544404006734	phosphorylation site [posttranslational modification]
544404006735	intermolecular recognition site; other site
544404006736	dimerization interface [polypeptide binding]; other site
544404006737	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
544404006738	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404006739	active site
544404006740	phosphorylation site [posttranslational modification]
544404006741	intermolecular recognition site; other site
544404006742	dimerization interface [polypeptide binding]; other site
544404006743	CheB methylesterase; Region: CheB_methylest; pfam01339
544404006744	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
544404006745	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
544404006746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404006747	S-adenosylmethionine binding site [chemical binding]; other site
544404006748	methyl-accepting protein IV; Provisional; Region: PRK09793
544404006749	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
544404006750	dimer interface [polypeptide binding]; other site
544404006751	ligand binding site [chemical binding]; other site
544404006752	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404006753	dimerization interface [polypeptide binding]; other site
544404006754	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
544404006755	dimer interface [polypeptide binding]; other site
544404006756	putative CheW interface [polypeptide binding]; other site
544404006757	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
544404006758	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
544404006759	dimer interface [polypeptide binding]; other site
544404006760	ligand binding site [chemical binding]; other site
544404006761	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404006762	dimerization interface [polypeptide binding]; other site
544404006763	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
544404006764	dimer interface [polypeptide binding]; other site
544404006765	putative CheW interface [polypeptide binding]; other site
544404006766	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
544404006767	putative CheA interaction surface; other site
544404006768	chemotaxis protein CheA; Provisional; Region: PRK10547
544404006769	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
544404006770	putative binding surface; other site
544404006771	active site
544404006772	CheY binding; Region: CheY-binding; pfam09078
544404006773	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
544404006774	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404006775	ATP binding site [chemical binding]; other site
544404006776	Mg2+ binding site [ion binding]; other site
544404006777	G-X-G motif; other site
544404006778	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
544404006779	flagellar motor protein MotB; Validated; Region: motB; PRK09041
544404006780	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
544404006781	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404006782	ligand binding site [chemical binding]; other site
544404006783	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
544404006784	flagellar motor protein MotA; Validated; Region: PRK09110
544404006785	transcriptional activator FlhC; Provisional; Region: PRK12722
544404006786	transcriptional activator FlhD; Provisional; Region: PRK02909
544404006787	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404006788	Ligand Binding Site [chemical binding]; other site
544404006789	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
544404006790	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
544404006791	active site
544404006792	homotetramer interface [polypeptide binding]; other site
544404006793	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
544404006794	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
544404006795	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404006796	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404006797	TM-ABC transporter signature motif; other site
544404006798	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
544404006799	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404006800	Walker A/P-loop; other site
544404006801	ATP binding site [chemical binding]; other site
544404006802	Q-loop/lid; other site
544404006803	ABC transporter signature motif; other site
544404006804	Walker B; other site
544404006805	D-loop; other site
544404006806	H-loop/switch region; other site
544404006807	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404006808	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
544404006809	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
544404006810	ligand binding site [chemical binding]; other site
544404006811	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
544404006812	Ferritin-like domain; Region: Ferritin; pfam00210
544404006813	ferroxidase diiron center [ion binding]; other site
544404006814	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
544404006815	YecR-like lipoprotein; Region: YecR; pfam13992
544404006816	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
544404006817	Ferritin-like domain; Region: Ferritin; pfam00210
544404006818	ferroxidase diiron center [ion binding]; other site
544404006819	probable metal-binding protein; Region: matur_matur; TIGR03853
544404006820	tyrosine transporter TyrP; Provisional; Region: PRK15132
544404006821	aromatic amino acid transport protein; Region: araaP; TIGR00837
544404006822	hypothetical protein; Provisional; Region: PRK10396
544404006823	yecA family protein; Region: ygfB_yecA; TIGR02292
544404006824	SEC-C motif; Region: SEC-C; pfam02810
544404006825	integrase; Provisional; Region: int; PHA02601
544404006826	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
544404006827	dimer interface [polypeptide binding]; other site
544404006828	active site
544404006829	catalytic residues [active]
544404006830	Int/Topo IB signature motif; other site
544404006831	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
544404006832	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
544404006833	Ash protein family; Region: Phage_ASH; pfam10554
544404006834	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
544404006835	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
544404006836	Mg binding site [ion binding]; other site
544404006837	nucleotide binding site [chemical binding]; other site
544404006838	putative protofilament interface [polypeptide binding]; other site
544404006839	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
544404006840	HTH-like domain; Region: HTH_21; pfam13276
544404006841	Integrase core domain; Region: rve; pfam00665
544404006842	Transposase; Region: HTH_Tnp_1; cl17663
544404006843	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404006844	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404006845	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
544404006846	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
544404006847	trimer interface [polypeptide binding]; other site
544404006848	active site
544404006849	substrate binding site [chemical binding]; other site
544404006850	CoA binding site [chemical binding]; other site
544404006851	Phage protein U [General function prediction only]; Region: COG3499
544404006852	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
544404006853	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
544404006854	Phage tail tube protein FII [General function prediction only]; Region: COG3498
544404006855	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
544404006856	Phage protein D [General function prediction only]; Region: COG3500
544404006857	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
544404006858	Helix-turn-helix domain; Region: HTH_38; pfam13936
544404006859	Integrase core domain; Region: rve; pfam00665
544404006860	Transposase; Region: HTH_Tnp_1; cl17663
544404006861	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404006862	putative transposase OrfB; Reviewed; Region: PHA02517
544404006863	HTH-like domain; Region: HTH_21; pfam13276
544404006864	Integrase core domain; Region: rve; pfam00665
544404006865	Integrase core domain; Region: rve_3; pfam13683
544404006866	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
544404006867	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
544404006868	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
544404006869	GIY-YIG motif/motif A; other site
544404006870	active site
544404006871	catalytic site [active]
544404006872	putative DNA binding site [nucleotide binding]; other site
544404006873	metal binding site [ion binding]; metal-binding site
544404006874	UvrB/uvrC motif; Region: UVR; pfam02151
544404006875	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
544404006876	Helix-hairpin-helix motif; Region: HHH; pfam00633
544404006877	response regulator; Provisional; Region: PRK09483
544404006878	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404006879	active site
544404006880	phosphorylation site [posttranslational modification]
544404006881	intermolecular recognition site; other site
544404006882	dimerization interface [polypeptide binding]; other site
544404006883	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404006884	DNA binding residues [nucleotide binding]
544404006885	dimerization interface [polypeptide binding]; other site
544404006886	hypothetical protein; Provisional; Region: PRK10613
544404006887	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
544404006888	Autoinducer binding domain; Region: Autoind_bind; pfam03472
544404006889	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404006890	DNA binding residues [nucleotide binding]
544404006891	dimerization interface [polypeptide binding]; other site
544404006892	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
544404006893	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
544404006894	Walker A/P-loop; other site
544404006895	ATP binding site [chemical binding]; other site
544404006896	Q-loop/lid; other site
544404006897	ABC transporter signature motif; other site
544404006898	Walker B; other site
544404006899	D-loop; other site
544404006900	H-loop/switch region; other site
544404006901	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
544404006902	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404006903	dimer interface [polypeptide binding]; other site
544404006904	conserved gate region; other site
544404006905	putative PBP binding loops; other site
544404006906	ABC-ATPase subunit interface; other site
544404006907	D-cysteine desulfhydrase; Validated; Region: PRK03910
544404006908	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
544404006909	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404006910	catalytic residue [active]
544404006911	cystine transporter subunit; Provisional; Region: PRK11260
544404006912	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404006913	substrate binding pocket [chemical binding]; other site
544404006914	membrane-bound complex binding site; other site
544404006915	hinge residues; other site
544404006916	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
544404006917	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
544404006918	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
544404006919	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
544404006920	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
544404006921	DNA binding residues [nucleotide binding]
544404006922	flagellin; Validated; Region: PRK08026
544404006923	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
544404006924	Flagellin protein; Region: FliC; pfam12445
544404006925	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
544404006926	flagellar capping protein; Reviewed; Region: fliD; PRK08032
544404006927	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
544404006928	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
544404006929	Flagellar protein FliS; Region: FliS; cl00654
544404006930	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
544404006931	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
544404006932	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
544404006933	active site
544404006934	Na/Ca binding site [ion binding]; other site
544404006935	catalytic site [active]
544404006936	lipoprotein; Provisional; Region: PRK10397
544404006937	putative inner membrane protein; Provisional; Region: PRK11099
544404006938	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
544404006939	CPxP  motif; other site
544404006940	hypothetical protein; Provisional; Region: PRK09951
544404006941	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
544404006942	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404006943	Coenzyme A binding pocket [chemical binding]; other site
544404006944	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
544404006945	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404006946	Coenzyme A binding pocket [chemical binding]; other site
544404006947	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
544404006948	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
544404006949	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
544404006950	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
544404006951	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
544404006952	flagellar motor switch protein FliG; Region: fliG; TIGR00207
544404006953	FliG C-terminal domain; Region: FliG_C; pfam01706
544404006954	flagellar assembly protein H; Validated; Region: fliH; PRK05687
544404006955	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
544404006956	Flagellar assembly protein FliH; Region: FliH; pfam02108
544404006957	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
544404006958	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
544404006959	Walker A motif/ATP binding site; other site
544404006960	Walker B motif; other site
544404006961	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
544404006962	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
544404006963	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
544404006964	flagellar hook-length control protein; Provisional; Region: PRK10118
544404006965	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
544404006966	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
544404006967	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
544404006968	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
544404006969	flagellar motor switch protein; Validated; Region: fliN; PRK05698
544404006970	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
544404006971	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
544404006972	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
544404006973	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
544404006974	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
544404006975	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404006976	DNA binding residues [nucleotide binding]
544404006977	dimerization interface [polypeptide binding]; other site
544404006978	hypothetical protein; Provisional; Region: PRK10708
544404006979	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
544404006980	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
544404006981	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404006982	active site
544404006983	motif I; other site
544404006984	motif II; other site
544404006985	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
544404006986	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404006987	metal binding site [ion binding]; metal-binding site
544404006988	active site
544404006989	I-site; other site
544404006990	Uncharacterized small protein [Function unknown]; Region: COG5475
544404006991	hypothetical protein; Provisional; Region: PRK10062
544404006992	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
544404006993	EamA-like transporter family; Region: EamA; pfam00892
544404006994	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
544404006995	additional DNA contacts [nucleotide binding]; other site
544404006996	mismatch recognition site; other site
544404006997	active site
544404006998	zinc binding site [ion binding]; other site
544404006999	DNA intercalation site [nucleotide binding]; other site
544404007000	DNA cytosine methylase; Provisional; Region: PRK10458
544404007001	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
544404007002	cofactor binding site; other site
544404007003	DNA binding site [nucleotide binding]
544404007004	substrate interaction site [chemical binding]; other site
544404007005	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
544404007006	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
544404007007	Zn2+ binding site [ion binding]; other site
544404007008	Mg2+ binding site [ion binding]; other site
544404007009	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
544404007010	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
544404007011	trimer interface [polypeptide binding]; other site
544404007012	eyelet of channel; other site
544404007013	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
544404007014	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
544404007015	chaperone protein HchA; Provisional; Region: PRK04155
544404007016	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
544404007017	dimer interface [polypeptide binding]; other site
544404007018	metal binding site [ion binding]; metal-binding site
544404007019	potential oxyanion hole; other site
544404007020	potential catalytic triad [active]
544404007021	conserved cys residue [active]
544404007022	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
544404007023	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404007024	dimer interface [polypeptide binding]; other site
544404007025	phosphorylation site [posttranslational modification]
544404007026	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404007027	ATP binding site [chemical binding]; other site
544404007028	Mg2+ binding site [ion binding]; other site
544404007029	G-X-G motif; other site
544404007030	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
544404007031	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404007032	active site
544404007033	phosphorylation site [posttranslational modification]
544404007034	intermolecular recognition site; other site
544404007035	dimerization interface [polypeptide binding]; other site
544404007036	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404007037	DNA binding site [nucleotide binding]
544404007038	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
544404007039	active site
544404007040	homotetramer interface [polypeptide binding]; other site
544404007041	TMAO/DMSO reductase; Reviewed; Region: PRK05363
544404007042	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
544404007043	Moco binding site; other site
544404007044	metal coordination site [ion binding]; other site
544404007045	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
544404007046	zinc/cadmium-binding protein; Provisional; Region: PRK10306
544404007047	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
544404007048	AvrPphF-ORF-2; Region: AvrPphF-ORF-2; pfam09143
544404007049	EspF protein repeat; Region: EspF; pfam04806
544404007050	EspF protein repeat; Region: EspF; pfam04806
544404007051	EspF protein repeat; Region: EspF; pfam04806
544404007052	EspF protein repeat; Region: EspF; pfam04806
544404007053	EspF protein repeat; Region: EspF; pfam04806
544404007054	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404007055	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404007056	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
544404007057	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404007058	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404007059	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404007060	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404007061	MPN+ (JAMM) motif; other site
544404007062	Zinc-binding site [ion binding]; other site
544404007063	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404007064	NlpC/P60 family; Region: NLPC_P60; cl17555
544404007065	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404007066	Phage-related protein [Function unknown]; Region: COG4718
544404007067	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404007068	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404007069	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404007070	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
544404007071	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
544404007072	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404007073	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404007074	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
544404007075	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
544404007076	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
544404007077	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
544404007078	tandem repeat interface [polypeptide binding]; other site
544404007079	oligomer interface [polypeptide binding]; other site
544404007080	active site residues [active]
544404007081	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404007082	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404007083	gpW; Region: gpW; pfam02831
544404007084	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
544404007085	Phage DNA packaging protein, Nu1 subunit of terminase [DNA replication, recombination, and repair]; Region: COG4220
544404007086	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
544404007087	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404007088	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404007089	catalytic residues [active]
544404007090	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
544404007091	Lysis protein S; Region: Lysis_S; pfam04971
544404007092	Transposase; Region: HTH_Tnp_1; cl17663
544404007093	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404007094	putative transposase OrfB; Reviewed; Region: PHA02517
544404007095	HTH-like domain; Region: HTH_21; pfam13276
544404007096	Integrase core domain; Region: rve; pfam00665
544404007097	Integrase core domain; Region: rve_3; pfam13683
544404007098	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404007099	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404007100	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
544404007101	tellurite resistance protein terB; Region: terB; cd07176
544404007102	putative metal binding site [ion binding]; other site
544404007103	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
544404007104	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
544404007105	Protein of unknown function (DUF968); Region: DUF968; pfam06147
544404007106	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404007107	Pyocin large subunit [General function prediction only]; Region: COG5529
544404007108	primosomal protein DnaI; Provisional; Region: PRK02854
544404007109	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404007110	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404007111	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
544404007112	non-specific DNA binding site [nucleotide binding]; other site
544404007113	salt bridge; other site
544404007114	sequence-specific DNA binding site [nucleotide binding]; other site
544404007115	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404007116	Catalytic site [active]
544404007117	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
544404007118	DicB protein; Region: DicB; pfam05358
544404007119	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
544404007120	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404007121	active site
544404007122	substrate binding site [chemical binding]; other site
544404007123	catalytic site [active]
544404007124	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404007125	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404007126	active site
544404007127	DNA binding site [nucleotide binding]
544404007128	Int/Topo IB signature motif; other site
544404007129	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
544404007130	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
544404007131	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007132	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007133	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007134	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007135	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007136	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007137	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007138	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007139	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
544404007140	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
544404007141	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
544404007142	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007143	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
544404007144	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007145	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007146	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404007147	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
544404007148	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
544404007149	shikimate transporter; Provisional; Region: PRK09952
544404007150	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404007151	putative substrate translocation pore; other site
544404007152	AMP nucleosidase; Provisional; Region: PRK08292
544404007153	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
544404007154	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
544404007155	hypothetical protein; Provisional; Region: PRK12378
544404007156	MATE family multidrug exporter; Provisional; Region: PRK10189
544404007157	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
544404007158	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
544404007159	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404007160	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
544404007161	putative substrate binding site [chemical binding]; other site
544404007162	dimerization interface [polypeptide binding]; other site
544404007163	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
544404007164	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404007165	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
544404007166	putative dimerization interface [polypeptide binding]; other site
544404007167	L,D-transpeptidase; Provisional; Region: PRK10190
544404007168	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
544404007169	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
544404007170	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
544404007171	putative dimer interface [polypeptide binding]; other site
544404007172	active site pocket [active]
544404007173	putative cataytic base [active]
544404007174	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
544404007175	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
544404007176	homotrimer interface [polypeptide binding]; other site
544404007177	Walker A motif; other site
544404007178	GTP binding site [chemical binding]; other site
544404007179	Walker B motif; other site
544404007180	Transposase; Region: HTH_Tnp_1; pfam01527
544404007181	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404007182	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404007183	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404007184	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404007185	homodimer interface [polypeptide binding]; other site
544404007186	putative GKAP docking site [polypeptide binding]; other site
544404007187	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404007188	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404007189	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404007190	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404007191	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404007192	putative transposase OrfB; Reviewed; Region: PHA02517
544404007193	HTH-like domain; Region: HTH_21; pfam13276
544404007194	Integrase core domain; Region: rve; pfam00665
544404007195	Integrase core domain; Region: rve_3; pfam13683
544404007196	Transposase; Region: HTH_Tnp_1; cl17663
544404007197	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404007198	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
544404007199	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404007200	N-terminal plug; other site
544404007201	ligand-binding site [chemical binding]; other site
544404007202	hypothetical protein; Provisional; Region: PRK09866
544404007203	YjcZ-like protein; Region: YjcZ; pfam13990
544404007204	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
544404007205	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
544404007206	nucleophile elbow; other site
544404007207	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
544404007208	Domain of unknown function (DUF932); Region: DUF932; pfam06067
544404007209	Antirestriction protein; Region: Antirestrict; pfam03230
544404007210	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
544404007211	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
544404007212	MPN+ (JAMM) motif; other site
544404007213	Zinc-binding site [ion binding]; other site
544404007214	Protein of unknown function (DUF987); Region: DUF987; pfam06174
544404007215	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
544404007216	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
544404007217	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
544404007218	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
544404007219	Switch II region; other site
544404007220	G4 box; other site
544404007221	G5 box; other site
544404007222	hypothetical protein; Provisional; Region: PRK05423
544404007223	Predicted membrane protein [Function unknown]; Region: COG1289
544404007224	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
544404007225	DNA gyrase inhibitor; Provisional; Region: PRK10016
544404007226	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
544404007227	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
544404007228	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
544404007229	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404007230	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404007231	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404007232	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404007233	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404007234	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404007235	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404007236	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
544404007237	Interdomain contacts; other site
544404007238	Cytokine receptor motif; other site
544404007239	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404007240	Fibronectin type III protein; Region: DUF3672; pfam12421
544404007241	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404007242	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404007243	MPN+ (JAMM) motif; other site
544404007244	Zinc-binding site [ion binding]; other site
544404007245	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404007246	NlpC/P60 family; Region: NLPC_P60; cl17555
544404007247	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
544404007248	Phage anti-repressor protein [Transcription]; Region: COG3561
544404007249	Arc-like DNA binding domain; Region: Arc; pfam03869
544404007250	Phage-related protein [Function unknown]; Region: COG4718
544404007251	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404007252	tape measure domain; Region: tape_meas_nterm; TIGR02675
544404007253	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
544404007254	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404007255	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
544404007256	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
544404007257	Immunoglobulin I-set domain; Region: I-set; pfam07679
544404007258	Immunoglobulin domain; Region: Ig_2; pfam13895
544404007259	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
544404007260	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
544404007261	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
544404007262	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
544404007263	oligomerization interface [polypeptide binding]; other site
544404007264	Phage-related protein [Function unknown]; Region: COG4695
544404007265	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
544404007266	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
544404007267	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
544404007268	Phage capsid family; Region: Phage_capsid; pfam05065
544404007269	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
544404007270	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
544404007271	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
544404007272	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
544404007273	active site
544404007274	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
544404007275	KilA-N domain; Region: KilA-N; pfam04383
544404007276	ORF11CD3 domain; Region: ORF11CD3; pfam10549
544404007277	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404007278	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404007279	catalytic residues [active]
544404007280	Lysis protein S; Region: Lysis_S; pfam04971
544404007281	Protein of unknown function (DUF826); Region: DUF826; pfam05696
544404007282	Protein of unknown function (DUF1378); Region: DUF1378; pfam07125
544404007283	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404007284	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404007285	Shiga-like toxin beta subunit; Region: SLT_beta; pfam02258
544404007286	Ribosome inactivating protein; Region: RIP; pfam00161
544404007287	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
544404007288	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
544404007289	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
544404007290	active site
544404007291	metal binding site [ion binding]; metal-binding site
544404007292	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
544404007293	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
544404007294	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645
544404007295	ORF6N domain; Region: ORF6N; pfam10543
544404007296	Phage anti-repressor protein [Transcription]; Region: COG3561
544404007297	ORF6N domain; Region: ORF6N; pfam10543
544404007298	phage N-6-adenine-methyltransferase; Region: phage_N6A_met; TIGR01712
544404007299	NinB protein; Region: NinB; pfam05772
544404007300	restriction alleviation protein, Lar family; Region: anti_R_Lar; TIGR03655
544404007301	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
544404007302	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
544404007303	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
544404007304	Walker A motif; other site
544404007305	ATP binding site [chemical binding]; other site
544404007306	Walker B motif; other site
544404007307	DNA binding loops [nucleotide binding]
544404007308	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
544404007309	Bacteriophage CII protein; Region: Phage_CII; pfam05269
544404007310	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404007311	non-specific DNA binding site [nucleotide binding]; other site
544404007312	salt bridge; other site
544404007313	sequence-specific DNA binding site [nucleotide binding]; other site
544404007314	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
544404007315	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404007316	non-specific DNA binding site [nucleotide binding]; other site
544404007317	salt bridge; other site
544404007318	sequence-specific DNA binding site [nucleotide binding]; other site
544404007319	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404007320	Catalytic site [active]
544404007321	Protein of unknown function (DUF2528); Region: DUF2528; pfam10800
544404007322	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
544404007323	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
544404007324	phage recombination protein Bet; Region: bet_lambda; TIGR01913
544404007325	putative transposase OrfB; Reviewed; Region: PHA02517
544404007326	HTH-like domain; Region: HTH_21; pfam13276
544404007327	Integrase core domain; Region: rve; pfam00665
544404007328	Integrase core domain; Region: rve_3; pfam13683
544404007329	Transposase; Region: HTH_Tnp_1; cl17663
544404007330	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404007331	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
544404007332	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
544404007333	DksA-like zinc finger domain containing protein; Region: PHA00080
544404007334	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
544404007335	Protein of unknown function (DUF551); Region: DUF551; pfam04448
544404007336	integrase; Provisional; Region: PRK09692
544404007337	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404007338	active site
544404007339	Int/Topo IB signature motif; other site
544404007340	exonuclease I; Provisional; Region: sbcB; PRK11779
544404007341	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
544404007342	active site
544404007343	catalytic site [active]
544404007344	substrate binding site [chemical binding]; other site
544404007345	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
544404007346	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
544404007347	CPxP  motif; other site
544404007348	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
544404007349	Sulphur transport; Region: Sulf_transp; pfam04143
544404007350	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
544404007351	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404007352	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
544404007353	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404007354	dimerization interface [polypeptide binding]; other site
544404007355	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
544404007356	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
544404007357	putative NAD(P) binding site [chemical binding]; other site
544404007358	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
544404007359	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
544404007360	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
544404007361	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
544404007362	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
544404007363	NAD binding site [chemical binding]; other site
544404007364	dimerization interface [polypeptide binding]; other site
544404007365	product binding site; other site
544404007366	substrate binding site [chemical binding]; other site
544404007367	zinc binding site [ion binding]; other site
544404007368	catalytic residues [active]
544404007369	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
544404007370	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404007371	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404007372	homodimer interface [polypeptide binding]; other site
544404007373	catalytic residue [active]
544404007374	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
544404007375	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404007376	active site
544404007377	motif I; other site
544404007378	motif II; other site
544404007379	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
544404007380	putative active site pocket [active]
544404007381	4-fold oligomerization interface [polypeptide binding]; other site
544404007382	metal binding residues [ion binding]; metal-binding site
544404007383	3-fold/trimer interface [polypeptide binding]; other site
544404007384	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
544404007385	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
544404007386	putative active site [active]
544404007387	oxyanion strand; other site
544404007388	catalytic triad [active]
544404007389	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
544404007390	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
544404007391	catalytic residues [active]
544404007392	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
544404007393	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
544404007394	substrate binding site [chemical binding]; other site
544404007395	glutamase interaction surface [polypeptide binding]; other site
544404007396	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
544404007397	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
544404007398	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
544404007399	metal binding site [ion binding]; metal-binding site
544404007400	chain length determinant protein WzzB; Provisional; Region: PRK15471
544404007401	Chain length determinant protein; Region: Wzz; pfam02706
544404007402	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
544404007403	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
544404007404	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
544404007405	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
544404007406	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
544404007407	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
544404007408	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
544404007409	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
544404007410	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
544404007411	putative trimer interface [polypeptide binding]; other site
544404007412	putative CoA binding site [chemical binding]; other site
544404007413	phosphomannomutase CpsG; Provisional; Region: PRK15414
544404007414	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
544404007415	active site
544404007416	substrate binding site [chemical binding]; other site
544404007417	metal binding site [ion binding]; metal-binding site
544404007418	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
544404007419	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
544404007420	Substrate binding site; other site
544404007421	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
544404007422	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
544404007423	active site
544404007424	GDP-Mannose binding site [chemical binding]; other site
544404007425	dimer interface [polypeptide binding]; other site
544404007426	modified nudix motif
544404007427	metal binding site [ion binding]; metal-binding site
544404007428	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
544404007429	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
544404007430	NADP binding site [chemical binding]; other site
544404007431	active site
544404007432	putative substrate binding site [chemical binding]; other site
544404007433	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
544404007434	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
544404007435	NADP-binding site; other site
544404007436	homotetramer interface [polypeptide binding]; other site
544404007437	substrate binding site [chemical binding]; other site
544404007438	homodimer interface [polypeptide binding]; other site
544404007439	active site
544404007440	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
544404007441	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
544404007442	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
544404007443	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
544404007444	inhibitor-cofactor binding pocket; inhibition site
544404007445	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404007446	catalytic residue [active]
544404007447	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
544404007448	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
544404007449	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
544404007450	active site
544404007451	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
544404007452	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
544404007453	active site
544404007454	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
544404007455	active site
544404007456	tetramer interface; other site
544404007457	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
544404007458	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
544404007459	putative NAD(P) binding site [chemical binding]; other site
544404007460	active site
544404007461	putative substrate binding site [chemical binding]; other site
544404007462	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
544404007463	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
544404007464	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
544404007465	putative ADP-binding pocket [chemical binding]; other site
544404007466	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
544404007467	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
544404007468	colanic acid exporter; Provisional; Region: PRK10459
544404007469	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
544404007470	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
544404007471	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
544404007472	phosphomannomutase CpsG; Provisional; Region: PRK15414
544404007473	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
544404007474	active site
544404007475	substrate binding site [chemical binding]; other site
544404007476	metal binding site [ion binding]; metal-binding site
544404007477	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
544404007478	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
544404007479	Substrate binding site; other site
544404007480	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
544404007481	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
544404007482	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
544404007483	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
544404007484	active site
544404007485	GDP-Mannose binding site [chemical binding]; other site
544404007486	dimer interface [polypeptide binding]; other site
544404007487	modified nudix motif
544404007488	metal binding site [ion binding]; metal-binding site
544404007489	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
544404007490	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
544404007491	NADP binding site [chemical binding]; other site
544404007492	active site
544404007493	putative substrate binding site [chemical binding]; other site
544404007494	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
544404007495	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
544404007496	NADP-binding site; other site
544404007497	homotetramer interface [polypeptide binding]; other site
544404007498	substrate binding site [chemical binding]; other site
544404007499	homodimer interface [polypeptide binding]; other site
544404007500	active site
544404007501	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
544404007502	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
544404007503	putative trimer interface [polypeptide binding]; other site
544404007504	putative active site [active]
544404007505	putative substrate binding site [chemical binding]; other site
544404007506	putative CoA binding site [chemical binding]; other site
544404007507	putative glycosyl transferase; Provisional; Region: PRK10063
544404007508	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
544404007509	metal-binding site
544404007510	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
544404007511	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
544404007512	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
544404007513	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
544404007514	putative acyl transferase; Provisional; Region: PRK10191
544404007515	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
544404007516	trimer interface [polypeptide binding]; other site
544404007517	active site
544404007518	substrate binding site [chemical binding]; other site
544404007519	CoA binding site [chemical binding]; other site
544404007520	putative glycosyl transferase; Provisional; Region: PRK10018
544404007521	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
544404007522	active site
544404007523	tyrosine kinase; Provisional; Region: PRK11519
544404007524	Chain length determinant protein; Region: Wzz; pfam02706
544404007525	Chain length determinant protein; Region: Wzz; cl15801
544404007526	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
544404007527	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
544404007528	Low molecular weight phosphatase family; Region: LMWPc; cd00115
544404007529	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
544404007530	active site
544404007531	polysaccharide export protein Wza; Provisional; Region: PRK15078
544404007532	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
544404007533	SLBB domain; Region: SLBB; pfam10531
544404007534	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
544404007535	FOG: CBS domain [General function prediction only]; Region: COG0517
544404007536	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
544404007537	Transporter associated domain; Region: CorC_HlyC; smart01091
544404007538	Phage-related protein [Function unknown]; Region: COG4679
544404007539	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
544404007540	putative assembly protein; Provisional; Region: PRK10833
544404007541	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
544404007542	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
544404007543	trimer interface [polypeptide binding]; other site
544404007544	active site
544404007545	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
544404007546	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
544404007547	ATP-binding site [chemical binding]; other site
544404007548	Sugar specificity; other site
544404007549	Pyrimidine base specificity; other site
544404007550	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
544404007551	AlkA N-terminal domain; Region: AlkA_N; smart01009
544404007552	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
544404007553	minor groove reading motif; other site
544404007554	helix-hairpin-helix signature motif; other site
544404007555	substrate binding pocket [chemical binding]; other site
544404007556	active site
544404007557	putative chaperone; Provisional; Region: PRK11678
544404007558	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
544404007559	nucleotide binding site [chemical binding]; other site
544404007560	putative NEF/HSP70 interaction site [polypeptide binding]; other site
544404007561	SBD interface [polypeptide binding]; other site
544404007562	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
544404007563	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
544404007564	substrate binding site [chemical binding]; other site
544404007565	activation loop (A-loop); other site
544404007566	Protein phosphatase 2C; Region: PP2C_2; pfam13672
544404007567	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
544404007568	metal ion-dependent adhesion site (MIDAS); other site
544404007569	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
544404007570	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404007571	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404007572	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
544404007573	Protein export membrane protein; Region: SecD_SecF; cl14618
544404007574	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
544404007575	putative transporter; Provisional; Region: PRK10504
544404007576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404007577	putative substrate translocation pore; other site
544404007578	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404007579	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
544404007580	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404007581	dimerization interface [polypeptide binding]; other site
544404007582	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404007583	dimer interface [polypeptide binding]; other site
544404007584	phosphorylation site [posttranslational modification]
544404007585	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404007586	ATP binding site [chemical binding]; other site
544404007587	Mg2+ binding site [ion binding]; other site
544404007588	G-X-G motif; other site
544404007589	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
544404007590	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404007591	active site
544404007592	phosphorylation site [posttranslational modification]
544404007593	intermolecular recognition site; other site
544404007594	dimerization interface [polypeptide binding]; other site
544404007595	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404007596	DNA binding site [nucleotide binding]
544404007597	Uncharacterized conserved protein [Function unknown]; Region: COG3422
544404007598	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
544404007599	putative protease; Provisional; Region: PRK15452
544404007600	Peptidase family U32; Region: Peptidase_U32; pfam01136
544404007601	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
544404007602	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
544404007603	tail protein; Provisional; Region: D; PHA02561
544404007604	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
544404007605	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
544404007606	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
544404007607	major tail tube protein; Provisional; Region: FII; PHA02600
544404007608	major tail sheath protein; Provisional; Region: FI; PHA02560
544404007609	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
544404007610	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
544404007611	catalytic residues [active]
544404007612	catalytic nucleophile [active]
544404007613	Presynaptic Site I dimer interface [polypeptide binding]; other site
544404007614	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
544404007615	Synaptic Flat tetramer interface [polypeptide binding]; other site
544404007616	Synaptic Site I dimer interface [polypeptide binding]; other site
544404007617	DNA binding site [nucleotide binding]
544404007618	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
544404007619	DNA-binding interface [nucleotide binding]; DNA binding site
544404007620	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404007621	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
544404007622	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
544404007623	Phage Tail Collar Domain; Region: Collar; pfam07484
544404007624	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
544404007625	baseplate assembly protein; Provisional; Region: J; PHA02568
544404007626	baseplate wedge subunit; Provisional; Region: W; PHA02516
544404007627	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
544404007628	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
544404007629	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
544404007630	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
544404007631	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
544404007632	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
544404007633	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404007634	catalytic residue [active]
544404007635	Phage holin family 2; Region: Phage_holin_2; pfam04550
544404007636	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
544404007637	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
544404007638	terminase endonuclease subunit; Provisional; Region: M; PHA02537
544404007639	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
544404007640	Phage major capsid protein, P2 family; Region: Phage_cap_P2; pfam05125
544404007641	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
544404007642	terminase ATPase subunit; Provisional; Region: P; PHA02535
544404007643	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
544404007644	portal vertex protein; Provisional; Region: Q; PHA02536
544404007645	Phage portal protein; Region: Phage_portal; pfam04860
544404007646	AAA domain; Region: AAA_23; pfam13476
544404007647	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404007648	Walker A/P-loop; other site
544404007649	ATP binding site [chemical binding]; other site
544404007650	Putative serine esterase (DUF676); Region: DUF676; pfam05057
544404007651	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
544404007652	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
544404007653	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
544404007654	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
544404007655	integrase; Provisional; Region: int; PHA02601
544404007656	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
544404007657	dimer interface [polypeptide binding]; other site
544404007658	active site
544404007659	catalytic residues [active]
544404007660	Int/Topo IB signature motif; other site
544404007661	lipid kinase; Reviewed; Region: PRK13054
544404007662	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
544404007663	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
544404007664	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
544404007665	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404007666	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
544404007667	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
544404007668	putative NAD(P) binding site [chemical binding]; other site
544404007669	catalytic Zn binding site [ion binding]; other site
544404007670	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
544404007671	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
544404007672	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
544404007673	active site
544404007674	P-loop; other site
544404007675	phosphorylation site [posttranslational modification]
544404007676	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404007677	active site
544404007678	phosphorylation site [posttranslational modification]
544404007679	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
544404007680	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
544404007681	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
544404007682	intersubunit interface [polypeptide binding]; other site
544404007683	active site
544404007684	zinc binding site [ion binding]; other site
544404007685	Na+ binding site [ion binding]; other site
544404007686	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
544404007687	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
544404007688	putative active site; other site
544404007689	catalytic residue [active]
544404007690	nucleoside transporter; Region: 2A0110; TIGR00889
544404007691	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404007692	putative substrate translocation pore; other site
544404007693	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
544404007694	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404007695	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
544404007696	substrate binding site [chemical binding]; other site
544404007697	ATP binding site [chemical binding]; other site
544404007698	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
544404007699	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404007700	DNA-binding site [nucleotide binding]; DNA binding site
544404007701	UTRA domain; Region: UTRA; pfam07702
544404007702	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
544404007703	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
544404007704	active site
544404007705	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
544404007706	dimer interface [polypeptide binding]; other site
544404007707	substrate binding site [chemical binding]; other site
544404007708	ATP binding site [chemical binding]; other site
544404007709	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
544404007710	substrate binding site [chemical binding]; other site
544404007711	multimerization interface [polypeptide binding]; other site
544404007712	ATP binding site [chemical binding]; other site
544404007713	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
544404007714	putative metal binding site [ion binding]; other site
544404007715	putative homodimer interface [polypeptide binding]; other site
544404007716	putative homotetramer interface [polypeptide binding]; other site
544404007717	putative homodimer-homodimer interface [polypeptide binding]; other site
544404007718	putative allosteric switch controlling residues; other site
544404007719	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
544404007720	Predicted integral membrane protein [Function unknown]; Region: COG5455
544404007721	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
544404007722	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
544404007723	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
544404007724	PapC N-terminal domain; Region: PapC_N; pfam13954
544404007725	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404007726	PapC C-terminal domain; Region: PapC_C; pfam13953
544404007727	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
544404007728	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404007729	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404007730	Fimbrial protein; Region: Fimbrial; cl01416
544404007731	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
544404007732	antiporter inner membrane protein; Provisional; Region: PRK11670
544404007733	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
544404007734	Walker A motif; other site
544404007735	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
544404007736	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
544404007737	active site
544404007738	HIGH motif; other site
544404007739	KMSKS motif; other site
544404007740	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
544404007741	tRNA binding surface [nucleotide binding]; other site
544404007742	anticodon binding site; other site
544404007743	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
544404007744	dimer interface [polypeptide binding]; other site
544404007745	putative tRNA-binding site [nucleotide binding]; other site
544404007746	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
544404007747	Transposase; Region: HTH_Tnp_1; cl17663
544404007748	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404007749	putative transposase OrfB; Reviewed; Region: PHA02517
544404007750	HTH-like domain; Region: HTH_21; pfam13276
544404007751	Integrase core domain; Region: rve; pfam00665
544404007752	Integrase core domain; Region: rve_3; pfam13683
544404007753	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
544404007754	similar to hypothetical protein
544404007755	similar to hypothetical protein
544404007756	MoxR-like ATPases [General function prediction only]; Region: COG0714
544404007757	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404007758	Walker A motif; other site
544404007759	ATP binding site [chemical binding]; other site
544404007760	Walker B motif; other site
544404007761	arginine finger; other site
544404007762	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
544404007763	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
544404007764	metal ion-dependent adhesion site (MIDAS); other site
544404007765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
544404007766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
544404007767	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
544404007768	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
544404007769	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
544404007770	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404007771	active site
544404007772	phosphorylation site [posttranslational modification]
544404007773	intermolecular recognition site; other site
544404007774	dimerization interface [polypeptide binding]; other site
544404007775	LytTr DNA-binding domain; Region: LytTR; pfam04397
544404007776	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
544404007777	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
544404007778	GAF domain; Region: GAF; pfam01590
544404007779	Histidine kinase; Region: His_kinase; pfam06580
544404007780	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404007781	ATP binding site [chemical binding]; other site
544404007782	Mg2+ binding site [ion binding]; other site
544404007783	G-X-G motif; other site
544404007784	DinI-like family; Region: DinI; pfam06183
544404007785	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404007786	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404007787	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
544404007788	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404007789	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
544404007790	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404007791	Putative phage tail protein; Region: Phage-tail_3; pfam13550
544404007792	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
544404007793	Interdomain contacts; other site
544404007794	Cytokine receptor motif; other site
544404007795	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404007796	Fibronectin type III protein; Region: DUF3672; pfam12421
544404007797	Phage-related protein, tail component [Function unknown]; Region: COG4723
544404007798	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
544404007799	MPN+ (JAMM) motif; other site
544404007800	Zinc-binding site [ion binding]; other site
544404007801	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
544404007802	NlpC/P60 family; Region: NLPC_P60; cl17555
544404007803	Phage-related protein [Function unknown]; Region: gp18; COG4672
544404007804	Phage-related protein [Function unknown]; Region: COG4718
544404007805	Phage-related minor tail protein [Function unknown]; Region: COG5281
544404007806	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404007807	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
544404007808	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
544404007809	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
544404007810	Minor tail protein T; Region: Phage_tail_T; cl05636
544404007811	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
544404007812	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
544404007813	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404007814	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
544404007815	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
544404007816	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
544404007817	Uncharacterized conserved protein [Function unknown]; Region: COG5471
544404007818	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
544404007819	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
544404007820	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
544404007821	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
544404007822	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
544404007823	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404007824	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
544404007825	ORF11CD3 domain; Region: ORF11CD3; pfam10549
544404007826	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404007827	catalytic residues [active]
544404007828	Lysis protein S; Region: Lysis_S; pfam04971
544404007829	Protein of unknown function (DUF826); Region: DUF826; pfam05696
544404007830	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404007831	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404007832	DNA methylase; Region: N6_N4_Mtase; cl17433
544404007833	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
544404007834	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
544404007835	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
544404007836	hypothetical protein; Provisional; Region: PRK09741
544404007837	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404007838	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
544404007839	substrate binding site [chemical binding]; other site
544404007840	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
544404007841	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
544404007842	catalytic residues [active]
544404007843	catalytic nucleophile [active]
544404007844	Recombinase; Region: Recombinase; pfam07508
544404007845	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
544404007846	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
544404007847	Replication protein P; Region: Phage_lambda_P; pfam06992
544404007848	Transposase; Region: HTH_Tnp_1; cl17663
544404007849	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404007850	putative transposase OrfB; Reviewed; Region: PHA02517
544404007851	HTH-like domain; Region: HTH_21; pfam13276
544404007852	Integrase core domain; Region: rve; pfam00665
544404007853	Integrase core domain; Region: rve_3; pfam13683
544404007854	Replication protein P; Region: Phage_lambda_P; pfam06992
544404007855	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
544404007856	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
544404007857	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
544404007858	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404007859	Predicted transcriptional regulator [Transcription]; Region: COG2932
544404007860	sequence-specific DNA binding site [nucleotide binding]; other site
544404007861	salt bridge; other site
544404007862	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404007863	Catalytic site [active]
544404007864	Uncharacterized conserved protein [Function unknown]; Region: COG4933
544404007865	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
544404007866	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
544404007867	phage recombination protein Bet; Region: bet_lambda; TIGR01913
544404007868	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
544404007869	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
544404007870	DksA-like zinc finger domain containing protein; Region: PHA00080
544404007871	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
544404007872	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
544404007873	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
544404007874	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
544404007875	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404007876	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
544404007877	Int/Topo IB signature motif; other site
544404007878	transcriptional regulator MirA; Provisional; Region: PRK15043
544404007879	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
544404007880	hypothetical protein; Provisional; Region: PRK13681
544404007881	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
544404007882	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404007883	dimer interface [polypeptide binding]; other site
544404007884	conserved gate region; other site
544404007885	putative PBP binding loops; other site
544404007886	ABC-ATPase subunit interface; other site
544404007887	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
544404007888	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
544404007889	Walker A/P-loop; other site
544404007890	ATP binding site [chemical binding]; other site
544404007891	Q-loop/lid; other site
544404007892	ABC transporter signature motif; other site
544404007893	Walker B; other site
544404007894	D-loop; other site
544404007895	H-loop/switch region; other site
544404007896	CBS domain; Region: CBS; pfam00571
544404007897	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404007898	dimer interface [polypeptide binding]; other site
544404007899	conserved gate region; other site
544404007900	ABC-ATPase subunit interface; other site
544404007901	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
544404007902	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
544404007903	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
544404007904	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
544404007905	D-lactate dehydrogenase; Provisional; Region: PRK11183
544404007906	FAD binding domain; Region: FAD_binding_4; pfam01565
544404007907	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
544404007908	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
544404007909	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
544404007910	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
544404007911	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
544404007912	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
544404007913	oxidoreductase; Provisional; Region: PRK12743
544404007914	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
544404007915	NAD(P) binding site [chemical binding]; other site
544404007916	active site
544404007917	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
544404007918	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
544404007919	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
544404007920	FMN binding site [chemical binding]; other site
544404007921	active site
544404007922	catalytic residues [active]
544404007923	substrate binding site [chemical binding]; other site
544404007924	salicylate hydroxylase; Provisional; Region: PRK08163
544404007925	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
544404007926	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
544404007927	maleylacetoacetate isomerase; Region: maiA; TIGR01262
544404007928	C-terminal domain interface [polypeptide binding]; other site
544404007929	GSH binding site (G-site) [chemical binding]; other site
544404007930	putative dimer interface [polypeptide binding]; other site
544404007931	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
544404007932	dimer interface [polypeptide binding]; other site
544404007933	N-terminal domain interface [polypeptide binding]; other site
544404007934	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
544404007935	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
544404007936	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
544404007937	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
544404007938	Cupin domain; Region: Cupin_2; pfam07883
544404007939	Cupin domain; Region: Cupin_2; cl17218
544404007940	benzoate transport; Region: 2A0115; TIGR00895
544404007941	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404007942	putative substrate translocation pore; other site
544404007943	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
544404007944	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404007945	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404007946	dimerization interface [polypeptide binding]; other site
544404007947	hypothetical protein; Provisional; Region: PRK01821
544404007948	hypothetical protein; Provisional; Region: PRK10711
544404007949	cytidine deaminase; Provisional; Region: PRK09027
544404007950	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
544404007951	active site
544404007952	catalytic motif [active]
544404007953	Zn binding site [ion binding]; other site
544404007954	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
544404007955	active site
544404007956	catalytic motif [active]
544404007957	Zn binding site [ion binding]; other site
544404007958	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
544404007959	putative active site [active]
544404007960	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
544404007961	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
544404007962	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
544404007963	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404007964	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
544404007965	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
544404007966	homodimer interface [polypeptide binding]; other site
544404007967	active site
544404007968	FMN binding site [chemical binding]; other site
544404007969	substrate binding site [chemical binding]; other site
544404007970	4Fe-4S binding domain; Region: Fer4; pfam00037
544404007971	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404007972	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404007973	TM-ABC transporter signature motif; other site
544404007974	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404007975	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
544404007976	Walker A/P-loop; other site
544404007977	ATP binding site [chemical binding]; other site
544404007978	Q-loop/lid; other site
544404007979	ABC transporter signature motif; other site
544404007980	Walker B; other site
544404007981	D-loop; other site
544404007982	H-loop/switch region; other site
544404007983	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404007984	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
544404007985	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
544404007986	ligand binding site [chemical binding]; other site
544404007987	calcium binding site [ion binding]; other site
544404007988	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
544404007989	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404007990	DNA binding site [nucleotide binding]
544404007991	domain linker motif; other site
544404007992	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
544404007993	dimerization interface (closed form) [polypeptide binding]; other site
544404007994	ligand binding site [chemical binding]; other site
544404007995	Predicted membrane protein [Function unknown]; Region: COG2311
544404007996	hypothetical protein; Provisional; Region: PRK10835
544404007997	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
544404007998	homodecamer interface [polypeptide binding]; other site
544404007999	GTP cyclohydrolase I; Provisional; Region: PLN03044
544404008000	active site
544404008001	putative catalytic site residues [active]
544404008002	zinc binding site [ion binding]; other site
544404008003	GTP-CH-I/GFRP interaction surface; other site
544404008004	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
544404008005	S-formylglutathione hydrolase; Region: PLN02442
544404008006	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
544404008007	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404008008	N-terminal plug; other site
544404008009	ligand-binding site [chemical binding]; other site
544404008010	lysine transporter; Provisional; Region: PRK10836
544404008011	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
544404008012	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404008013	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
544404008014	putative dimerization interface [polypeptide binding]; other site
544404008015	conserved hypothetical integral membrane protein; Region: TIGR00698
544404008016	endonuclease IV; Provisional; Region: PRK01060
544404008017	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
544404008018	AP (apurinic/apyrimidinic) site pocket; other site
544404008019	DNA interaction; other site
544404008020	Metal-binding active site; metal-binding site
544404008021	putative kinase; Provisional; Region: PRK09954
544404008022	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
544404008023	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
544404008024	substrate binding site [chemical binding]; other site
544404008025	ATP binding site [chemical binding]; other site
544404008026	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
544404008027	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
544404008028	Nucleoside recognition; Region: Gate; pfam07670
544404008029	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
544404008030	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
544404008031	active site
544404008032	tetramer interface [polypeptide binding]; other site
544404008033	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
544404008034	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
544404008035	ligand binding site [chemical binding]; other site
544404008036	flexible hinge region; other site
544404008037	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
544404008038	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
544404008039	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
544404008040	Nucleoside recognition; Region: Gate; pfam07670
544404008041	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
544404008042	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
544404008043	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
544404008044	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404008045	substrate binding site [chemical binding]; other site
544404008046	ATP binding site [chemical binding]; other site
544404008047	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
544404008048	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
544404008049	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
544404008050	active site
544404008051	P-loop; other site
544404008052	phosphorylation site [posttranslational modification]
544404008053	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
544404008054	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
544404008055	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
544404008056	putative substrate binding site [chemical binding]; other site
544404008057	putative ATP binding site [chemical binding]; other site
544404008058	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
544404008059	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404008060	active site
544404008061	phosphorylation site [posttranslational modification]
544404008062	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
544404008063	dimerization domain swap beta strand [polypeptide binding]; other site
544404008064	regulatory protein interface [polypeptide binding]; other site
544404008065	active site
544404008066	regulatory phosphorylation site [posttranslational modification]; other site
544404008067	sugar efflux transporter B; Provisional; Region: PRK15011
544404008068	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008069	putative substrate translocation pore; other site
544404008070	Flagellin N-methylase; Region: FliB; pfam03692
544404008071	elongation factor P; Provisional; Region: PRK04542
544404008072	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
544404008073	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
544404008074	RNA binding site [nucleotide binding]; other site
544404008075	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
544404008076	RNA binding site [nucleotide binding]; other site
544404008077	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
544404008078	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
544404008079	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
544404008080	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
544404008081	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
544404008082	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
544404008083	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
544404008084	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
544404008085	active site
544404008086	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
544404008087	NlpC/P60 family; Region: NLPC_P60; pfam00877
544404008088	phage resistance protein; Provisional; Region: PRK10551
544404008089	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
544404008090	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404008091	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
544404008092	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
544404008093	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
544404008094	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404008095	dimer interface [polypeptide binding]; other site
544404008096	conserved gate region; other site
544404008097	putative PBP binding loops; other site
544404008098	ABC-ATPase subunit interface; other site
544404008099	microcin C ABC transporter permease; Provisional; Region: PRK15021
544404008100	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404008101	dimer interface [polypeptide binding]; other site
544404008102	conserved gate region; other site
544404008103	ABC-ATPase subunit interface; other site
544404008104	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
544404008105	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404008106	Walker A/P-loop; other site
544404008107	ATP binding site [chemical binding]; other site
544404008108	Q-loop/lid; other site
544404008109	ABC transporter signature motif; other site
544404008110	Walker B; other site
544404008111	D-loop; other site
544404008112	H-loop/switch region; other site
544404008113	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
544404008114	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404008115	Walker A/P-loop; other site
544404008116	ATP binding site [chemical binding]; other site
544404008117	Q-loop/lid; other site
544404008118	ABC transporter signature motif; other site
544404008119	Walker B; other site
544404008120	D-loop; other site
544404008121	H-loop/switch region; other site
544404008122	hypothetical protein; Provisional; Region: PRK11835
544404008123	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008124	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
544404008125	putative substrate translocation pore; other site
544404008126	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
544404008127	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404008128	RNA binding surface [nucleotide binding]; other site
544404008129	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
544404008130	active site
544404008131	uracil binding [chemical binding]; other site
544404008132	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
544404008133	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404008134	ATP binding site [chemical binding]; other site
544404008135	putative Mg++ binding site [ion binding]; other site
544404008136	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404008137	nucleotide binding region [chemical binding]; other site
544404008138	ATP-binding site [chemical binding]; other site
544404008139	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
544404008140	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
544404008141	5S rRNA interface [nucleotide binding]; other site
544404008142	CTC domain interface [polypeptide binding]; other site
544404008143	L16 interface [polypeptide binding]; other site
544404008144	Nucleoid-associated protein [General function prediction only]; Region: COG3081
544404008145	nucleoid-associated protein NdpA; Validated; Region: PRK00378
544404008146	hypothetical protein; Provisional; Region: PRK13689
544404008147	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
544404008148	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
544404008149	Sulfatase; Region: Sulfatase; pfam00884
544404008150	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
544404008151	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
544404008152	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
544404008153	Autotransporter beta-domain; Region: Autotransporter; pfam03797
544404008154	transcriptional regulator NarP; Provisional; Region: PRK10403
544404008155	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404008156	active site
544404008157	phosphorylation site [posttranslational modification]
544404008158	intermolecular recognition site; other site
544404008159	dimerization interface [polypeptide binding]; other site
544404008160	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404008161	DNA binding residues [nucleotide binding]
544404008162	dimerization interface [polypeptide binding]; other site
544404008163	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
544404008164	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
544404008165	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
544404008166	binding surface
544404008167	TPR motif; other site
544404008168	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
544404008169	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
544404008170	catalytic residues [active]
544404008171	central insert; other site
544404008172	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
544404008173	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
544404008174	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
544404008175	heme exporter protein CcmC; Region: ccmC; TIGR01191
544404008176	heme exporter protein CcmB; Region: ccmB; TIGR01190
544404008177	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
544404008178	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
544404008179	Walker A/P-loop; other site
544404008180	ATP binding site [chemical binding]; other site
544404008181	Q-loop/lid; other site
544404008182	ABC transporter signature motif; other site
544404008183	Walker B; other site
544404008184	D-loop; other site
544404008185	H-loop/switch region; other site
544404008186	cytochrome c-type protein NapC; Provisional; Region: PRK10617
544404008187	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
544404008188	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
544404008189	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
544404008190	4Fe-4S binding domain; Region: Fer4_5; pfam12801
544404008191	4Fe-4S binding domain; Region: Fer4; cl02805
544404008192	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
544404008193	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
544404008194	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
544404008195	[4Fe-4S] binding site [ion binding]; other site
544404008196	molybdopterin cofactor binding site; other site
544404008197	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
544404008198	molybdopterin cofactor binding site; other site
544404008199	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
544404008200	ferredoxin-type protein; Provisional; Region: PRK10194
544404008201	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
544404008202	secondary substrate binding site; other site
544404008203	primary substrate binding site; other site
544404008204	inhibition loop; other site
544404008205	dimerization interface [polypeptide binding]; other site
544404008206	malate:quinone oxidoreductase; Validated; Region: PRK05257
544404008207	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
544404008208	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
544404008209	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
544404008210	Walker A/P-loop; other site
544404008211	ATP binding site [chemical binding]; other site
544404008212	Q-loop/lid; other site
544404008213	ABC transporter signature motif; other site
544404008214	Walker B; other site
544404008215	D-loop; other site
544404008216	H-loop/switch region; other site
544404008217	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
544404008218	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
544404008219	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
544404008220	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404008221	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404008222	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
544404008223	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
544404008224	DNA binding site [nucleotide binding]
544404008225	active site
544404008226	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
544404008227	ApbE family; Region: ApbE; pfam02424
544404008228	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
544404008229	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
544404008230	trimer interface [polypeptide binding]; other site
544404008231	eyelet of channel; other site
544404008232	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
544404008233	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404008234	ATP binding site [chemical binding]; other site
544404008235	G-X-G motif; other site
544404008236	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
544404008237	putative binding surface; other site
544404008238	active site
544404008239	transcriptional regulator RcsB; Provisional; Region: PRK10840
544404008240	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404008241	active site
544404008242	phosphorylation site [posttranslational modification]
544404008243	intermolecular recognition site; other site
544404008244	dimerization interface [polypeptide binding]; other site
544404008245	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404008246	DNA binding residues [nucleotide binding]
544404008247	dimerization interface [polypeptide binding]; other site
544404008248	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
544404008249	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404008250	dimer interface [polypeptide binding]; other site
544404008251	phosphorylation site [posttranslational modification]
544404008252	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404008253	ATP binding site [chemical binding]; other site
544404008254	Mg2+ binding site [ion binding]; other site
544404008255	G-X-G motif; other site
544404008256	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
544404008257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404008258	active site
544404008259	phosphorylation site [posttranslational modification]
544404008260	intermolecular recognition site; other site
544404008261	dimerization interface [polypeptide binding]; other site
544404008262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
544404008263	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
544404008264	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
544404008265	MG2 domain; Region: A2M_N; pfam01835
544404008266	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
544404008267	Alpha-2-macroglobulin family; Region: A2M; pfam00207
544404008268	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
544404008269	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
544404008270	DNA gyrase subunit A; Validated; Region: PRK05560
544404008271	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
544404008272	CAP-like domain; other site
544404008273	active site
544404008274	primary dimer interface [polypeptide binding]; other site
544404008275	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404008276	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404008277	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404008278	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404008279	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404008280	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404008281	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
544404008282	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404008283	S-adenosylmethionine binding site [chemical binding]; other site
544404008284	adhesin; Provisional; Region: PRK09752
544404008285	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
544404008286	Autotransporter beta-domain; Region: Autotransporter; pfam03797
544404008287	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
544404008288	ATP cone domain; Region: ATP-cone; pfam03477
544404008289	Class I ribonucleotide reductase; Region: RNR_I; cd01679
544404008290	active site
544404008291	dimer interface [polypeptide binding]; other site
544404008292	catalytic residues [active]
544404008293	effector binding site; other site
544404008294	R2 peptide binding site; other site
544404008295	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
544404008296	dimer interface [polypeptide binding]; other site
544404008297	putative radical transfer pathway; other site
544404008298	diiron center [ion binding]; other site
544404008299	tyrosyl radical; other site
544404008300	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
544404008301	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404008302	catalytic loop [active]
544404008303	iron binding site [ion binding]; other site
544404008304	hypothetical protein; Provisional; Region: PRK09902
544404008305	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404008306	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008307	putative substrate translocation pore; other site
544404008308	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404008309	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404008310	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
544404008311	dimerization interface [polypeptide binding]; other site
544404008312	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
544404008313	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
544404008314	active site
544404008315	catalytic site [active]
544404008316	metal binding site [ion binding]; metal-binding site
544404008317	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
544404008318	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008319	putative substrate translocation pore; other site
544404008320	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
544404008321	hydroxyglutarate oxidase; Provisional; Region: PRK11728
544404008322	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
544404008323	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
544404008324	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
544404008325	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
544404008326	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404008327	Cysteine-rich domain; Region: CCG; pfam02754
544404008328	Cysteine-rich domain; Region: CCG; pfam02754
544404008329	hypothetical protein; Provisional; Region: PRK09956
544404008330	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
544404008331	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
544404008332	D-galactonate transporter; Region: 2A0114; TIGR00893
544404008333	Transposase; Region: HTH_Tnp_1; cl17663
544404008334	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404008335	putative transposase OrfB; Reviewed; Region: PHA02517
544404008336	HTH-like domain; Region: HTH_21; pfam13276
544404008337	Integrase core domain; Region: rve; pfam00665
544404008338	Integrase core domain; Region: rve_3; pfam13683
544404008339	L-rhamnonate dehydratase; Provisional; Region: PRK15440
544404008340	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
544404008341	putative active site pocket [active]
544404008342	putative metal binding site [ion binding]; other site
544404008343	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
544404008344	Transcriptional regulator [Transcription]; Region: IclR; COG1414
544404008345	Bacterial transcriptional regulator; Region: IclR; pfam01614
544404008346	hypothetical protein; Provisional; Region: PRK03673
544404008347	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
544404008348	putative MPT binding site; other site
544404008349	Competence-damaged protein; Region: CinA; cl00666
544404008350	YfaZ precursor; Region: YfaZ; pfam07437
544404008351	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
544404008352	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
544404008353	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
544404008354	catalytic core [active]
544404008355	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
544404008356	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
544404008357	inhibitor-cofactor binding pocket; inhibition site
544404008358	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404008359	catalytic residue [active]
544404008360	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
544404008361	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
544404008362	Ligand binding site; other site
544404008363	Putative Catalytic site; other site
544404008364	DXD motif; other site
544404008365	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
544404008366	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
544404008367	substrate binding site [chemical binding]; other site
544404008368	cosubstrate binding site; other site
544404008369	catalytic site [active]
544404008370	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
544404008371	active site
544404008372	hexamer interface [polypeptide binding]; other site
544404008373	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
544404008374	NAD binding site [chemical binding]; other site
544404008375	substrate binding site [chemical binding]; other site
544404008376	active site
544404008377	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
544404008378	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
544404008379	putative active site [active]
544404008380	putative catalytic site [active]
544404008381	putative Zn binding site [ion binding]; other site
544404008382	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
544404008383	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
544404008384	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
544404008385	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
544404008386	signal transduction protein PmrD; Provisional; Region: PRK15450
544404008387	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
544404008388	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
544404008389	acyl-activating enzyme (AAE) consensus motif; other site
544404008390	putative AMP binding site [chemical binding]; other site
544404008391	putative active site [active]
544404008392	putative CoA binding site [chemical binding]; other site
544404008393	O-succinylbenzoate synthase; Provisional; Region: PRK05105
544404008394	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
544404008395	active site
544404008396	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
544404008397	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
544404008398	substrate binding site [chemical binding]; other site
544404008399	oxyanion hole (OAH) forming residues; other site
544404008400	trimer interface [polypeptide binding]; other site
544404008401	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
544404008402	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
544404008403	nucleophilic elbow; other site
544404008404	catalytic triad; other site
544404008405	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
544404008406	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
544404008407	dimer interface [polypeptide binding]; other site
544404008408	tetramer interface [polypeptide binding]; other site
544404008409	PYR/PP interface [polypeptide binding]; other site
544404008410	TPP binding site [chemical binding]; other site
544404008411	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
544404008412	TPP-binding site; other site
544404008413	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
544404008414	isochorismate synthases; Region: isochor_syn; TIGR00543
544404008415	hypothetical protein; Provisional; Region: PRK10404
544404008416	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404008417	Coenzyme A binding pocket [chemical binding]; other site
544404008418	ribonuclease BN; Region: true_RNase_BN; TIGR02649
544404008419	deubiquitinase; Provisional; Region: PRK11836
544404008420	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
544404008421	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
544404008422	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
544404008423	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404008424	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
544404008425	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404008426	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
544404008427	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
544404008428	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404008429	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
544404008430	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
544404008431	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
544404008432	4Fe-4S binding domain; Region: Fer4; pfam00037
544404008433	4Fe-4S binding domain; Region: Fer4; pfam00037
544404008434	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
544404008435	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
544404008436	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404008437	catalytic loop [active]
544404008438	iron binding site [ion binding]; other site
544404008439	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
544404008440	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
544404008441	[4Fe-4S] binding site [ion binding]; other site
544404008442	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
544404008443	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
544404008444	SLBB domain; Region: SLBB; pfam10531
544404008445	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
544404008446	NADH dehydrogenase subunit E; Validated; Region: PRK07539
544404008447	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
544404008448	putative dimer interface [polypeptide binding]; other site
544404008449	[2Fe-2S] cluster binding site [ion binding]; other site
544404008450	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
544404008451	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
544404008452	NADH dehydrogenase subunit D; Validated; Region: PRK06075
544404008453	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
544404008454	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
544404008455	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
544404008456	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404008457	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
544404008458	putative dimerization interface [polypeptide binding]; other site
544404008459	aminotransferase AlaT; Validated; Region: PRK09265
544404008460	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404008461	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404008462	homodimer interface [polypeptide binding]; other site
544404008463	catalytic residue [active]
544404008464	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
544404008465	Zn2+ binding site [ion binding]; other site
544404008466	Mg2+ binding site [ion binding]; other site
544404008467	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
544404008468	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
544404008469	TrkA-C domain; Region: TrkA_C; pfam02080
544404008470	TrkA-C domain; Region: TrkA_C; pfam02080
544404008471	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
544404008472	putative phosphatase; Provisional; Region: PRK11587
544404008473	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
544404008474	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404008475	motif II; other site
544404008476	hypothetical protein; Validated; Region: PRK05445
544404008477	hypothetical protein; Provisional; Region: PRK01816
544404008478	propionate/acetate kinase; Provisional; Region: PRK12379
544404008479	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
544404008480	phosphate acetyltransferase; Reviewed; Region: PRK05632
544404008481	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
544404008482	DRTGG domain; Region: DRTGG; pfam07085
544404008483	phosphate acetyltransferase; Region: pta; TIGR00651
544404008484	hypothetical protein; Provisional; Region: PRK11588
544404008485	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
544404008486	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
544404008487	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
544404008488	nudix motif; other site
544404008489	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
544404008490	active site
544404008491	metal binding site [ion binding]; metal-binding site
544404008492	homotetramer interface [polypeptide binding]; other site
544404008493	glutathione S-transferase; Provisional; Region: PRK15113
544404008494	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
544404008495	C-terminal domain interface [polypeptide binding]; other site
544404008496	GSH binding site (G-site) [chemical binding]; other site
544404008497	dimer interface [polypeptide binding]; other site
544404008498	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
544404008499	N-terminal domain interface [polypeptide binding]; other site
544404008500	putative dimer interface [polypeptide binding]; other site
544404008501	putative substrate binding pocket (H-site) [chemical binding]; other site
544404008502	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
544404008503	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
544404008504	C-terminal domain interface [polypeptide binding]; other site
544404008505	GSH binding site (G-site) [chemical binding]; other site
544404008506	dimer interface [polypeptide binding]; other site
544404008507	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
544404008508	N-terminal domain interface [polypeptide binding]; other site
544404008509	putative dimer interface [polypeptide binding]; other site
544404008510	active site
544404008511	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
544404008512	homooctamer interface [polypeptide binding]; other site
544404008513	active site
544404008514	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
544404008515	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
544404008516	putative NAD(P) binding site [chemical binding]; other site
544404008517	putative active site [active]
544404008518	putative transposase; Provisional; Region: PRK09857
544404008519	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
544404008520	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
544404008521	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
544404008522	Walker A/P-loop; other site
544404008523	ATP binding site [chemical binding]; other site
544404008524	Q-loop/lid; other site
544404008525	ABC transporter signature motif; other site
544404008526	Walker B; other site
544404008527	D-loop; other site
544404008528	H-loop/switch region; other site
544404008529	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404008530	dimer interface [polypeptide binding]; other site
544404008531	conserved gate region; other site
544404008532	putative PBP binding loops; other site
544404008533	ABC-ATPase subunit interface; other site
544404008534	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
544404008535	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404008536	dimer interface [polypeptide binding]; other site
544404008537	conserved gate region; other site
544404008538	putative PBP binding loops; other site
544404008539	ABC-ATPase subunit interface; other site
544404008540	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
544404008541	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404008542	substrate binding pocket [chemical binding]; other site
544404008543	membrane-bound complex binding site; other site
544404008544	hinge residues; other site
544404008545	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
544404008546	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404008547	substrate binding pocket [chemical binding]; other site
544404008548	membrane-bound complex binding site; other site
544404008549	hinge residues; other site
544404008550	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
544404008551	Flavoprotein; Region: Flavoprotein; pfam02441
544404008552	amidophosphoribosyltransferase; Provisional; Region: PRK09246
544404008553	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
544404008554	active site
544404008555	tetramer interface [polypeptide binding]; other site
544404008556	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404008557	active site
544404008558	colicin V production protein; Provisional; Region: PRK10845
544404008559	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
544404008560	cell division protein DedD; Provisional; Region: PRK11633
544404008561	Sporulation related domain; Region: SPOR; pfam05036
544404008562	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
544404008563	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
544404008564	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
544404008565	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
544404008566	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
544404008567	hypothetical protein; Provisional; Region: PRK10847
544404008568	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
544404008569	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
544404008570	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
544404008571	dimerization interface 3.5A [polypeptide binding]; other site
544404008572	active site
544404008573	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
544404008574	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
544404008575	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
544404008576	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
544404008577	ligand binding site [chemical binding]; other site
544404008578	NAD binding site [chemical binding]; other site
544404008579	catalytic site [active]
544404008580	homodimer interface [polypeptide binding]; other site
544404008581	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
544404008582	putative transporter; Provisional; Region: PRK12382
544404008583	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008584	putative substrate translocation pore; other site
544404008585	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
544404008586	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
544404008587	dimer interface [polypeptide binding]; other site
544404008588	active site
544404008589	Uncharacterized conserved protein [Function unknown]; Region: COG4121
544404008590	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
544404008591	YfcL protein; Region: YfcL; pfam08891
544404008592	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
544404008593	hypothetical protein; Provisional; Region: PRK10621
544404008594	Predicted permeases [General function prediction only]; Region: COG0730
544404008595	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
544404008596	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
544404008597	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
544404008598	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
544404008599	Tetramer interface [polypeptide binding]; other site
544404008600	active site
544404008601	FMN-binding site [chemical binding]; other site
544404008602	HemK family putative methylases; Region: hemK_fam; TIGR00536
544404008603	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404008604	S-adenosylmethionine binding site [chemical binding]; other site
544404008605	hypothetical protein; Provisional; Region: PRK04946
544404008606	Smr domain; Region: Smr; pfam01713
544404008607	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
544404008608	Fimbrial protein; Region: Fimbrial; cl01416
544404008609	Fimbrial protein; Region: Fimbrial; cl01416
544404008610	Fimbrial protein; Region: Fimbrial; cl01416
544404008611	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404008612	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404008613	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
544404008614	PapC N-terminal domain; Region: PapC_N; pfam13954
544404008615	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404008616	PapC C-terminal domain; Region: PapC_C; pfam13953
544404008617	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404008618	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
544404008619	catalytic core [active]
544404008620	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
544404008621	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
544404008622	substrate binding site [chemical binding]; other site
544404008623	oxyanion hole (OAH) forming residues; other site
544404008624	trimer interface [polypeptide binding]; other site
544404008625	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
544404008626	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
544404008627	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
544404008628	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
544404008629	dimer interface [polypeptide binding]; other site
544404008630	active site
544404008631	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
544404008632	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
544404008633	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
544404008634	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
544404008635	transcription termination factor Rho; Provisional; Region: PRK12678
544404008636	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404008637	Phage-related protein, tail component [Function unknown]; Region: COG4733
544404008638	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
544404008639	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404008640	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404008641	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
544404008642	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
544404008643	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404008644	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
544404008645	Transposase; Region: HTH_Tnp_1; cl17663
544404008646	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404008647	putative transposase OrfB; Reviewed; Region: PHA02517
544404008648	HTH-like domain; Region: HTH_21; pfam13276
544404008649	Integrase core domain; Region: rve; pfam00665
544404008650	Integrase core domain; Region: rve_3; pfam13683
544404008651	large terminase protein; Provisional; Region: 17; PHA02533
544404008652	large terminase protein; Provisional; Region: 17; PHA02533
544404008653	Bor protein; Region: Lambda_Bor; pfam06291
544404008654	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
544404008655	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
544404008656	ORF11CD3 domain; Region: ORF11CD3; pfam10549
544404008657	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
544404008658	catalytic residues [active]
544404008659	Protein of unknown function (DUF826); Region: DUF826; pfam05696
544404008660	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404008661	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404008662	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
544404008663	Shiga-like toxin beta subunit; Region: SLT_beta; pfam02258
544404008664	Ribosome inactivating protein; Region: RIP; pfam00161
544404008665	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
544404008666	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
544404008667	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
544404008668	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645
544404008669	ORF6N domain; Region: ORF6N; pfam10543
544404008670	Phage anti-repressor protein [Transcription]; Region: COG3561
544404008671	NINE Protein; Region: NinE; pfam05322
544404008672	phage N-6-adenine-methyltransferase; Region: phage_N6A_met; TIGR01712
544404008673	NUMOD4 motif; Region: NUMOD4; pfam07463
544404008674	HNH endonuclease; Region: HNH_3; pfam13392
544404008675	GIYX(10-11)YIG family of class I homing endonucleases C-terminus (GIY-YIG_Cterm). Homing endonucleases promote the mobility of intron or intein by recognizing and cleaving a homologous allele that lacks the sequence. They catalyze a double-strand break...; Region: GIY-YIG_Cterm; cl11508
544404008676	NinB protein; Region: NinB; pfam05772
544404008677	Replication protein P; Region: Phage_lambda_P; pfam06992
544404008678	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
544404008679	Bacteriophage CII protein; Region: Phage_CII; pfam05269
544404008680	Helix-turn-helix domain; Region: HTH_17; pfam12728
544404008681	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404008682	non-specific DNA binding site [nucleotide binding]; other site
544404008683	salt bridge; other site
544404008684	sequence-specific DNA binding site [nucleotide binding]; other site
544404008685	Predicted transcriptional regulator [Transcription]; Region: COG2932
544404008686	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404008687	Catalytic site [active]
544404008688	Protein of unknown function (DUF3024); Region: DUF3024; pfam11225
544404008689	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cl17280
544404008690	Catalytic domain of Protein Kinases; Region: PKc; cd00180
544404008691	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
544404008692	active site
544404008693	ATP binding site [chemical binding]; other site
544404008694	substrate binding site [chemical binding]; other site
544404008695	activation loop (A-loop); other site
544404008696	Protein of unknown function (DUF2528); Region: DUF2528; pfam10800
544404008697	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
544404008698	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
544404008699	phage recombination protein Bet; Region: bet_lambda; TIGR01913
544404008700	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
544404008701	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
544404008702	Protein of unknown function (DUF551); Region: DUF551; pfam04448
544404008703	Phage anti-repressor protein [Transcription]; Region: COG3561
544404008704	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
544404008705	MT-A70; Region: MT-A70; cl01947
544404008706	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
544404008707	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
544404008708	Helix-turn-helix domain; Region: HTH_17; cl17695
544404008709	integrase; Provisional; Region: PRK09692
544404008710	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404008711	active site
544404008712	Int/Topo IB signature motif; other site
544404008713	integrase; Provisional; Region: PRK09692
544404008714	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404008715	active site
544404008716	Int/Topo IB signature motif; other site
544404008717	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
544404008718	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism]; Region: COG3936
544404008719	Protein of unknown function (DUF2824); Region: DUF2824; cl10279
544404008720	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
544404008721	Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient...; Region: SR_Res_par; cd03767
544404008722	catalytic residues [active]
544404008723	catalytic nucleophile [active]
544404008724	Methyltransferase domain; Region: Methyltransf_27; pfam13708
544404008725	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
544404008726	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008727	putative substrate translocation pore; other site
544404008728	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404008729	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
544404008730	putative substrate binding site [chemical binding]; other site
544404008731	putative ATP binding site [chemical binding]; other site
544404008732	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
544404008733	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
544404008734	substrate binding [chemical binding]; other site
544404008735	active site
544404008736	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
544404008737	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404008738	DNA binding site [nucleotide binding]
544404008739	domain linker motif; other site
544404008740	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
544404008741	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
544404008742	putative dimerization interface [polypeptide binding]; other site
544404008743	putative ligand binding site [chemical binding]; other site
544404008744	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
544404008745	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
544404008746	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
544404008747	catalytic residue [active]
544404008748	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
544404008749	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008750	putative substrate translocation pore; other site
544404008751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404008752	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
544404008753	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404008754	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404008755	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
544404008756	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404008757	active site
544404008758	phosphorylation site [posttranslational modification]
544404008759	intermolecular recognition site; other site
544404008760	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404008761	DNA binding residues [nucleotide binding]
544404008762	dimerization interface [polypeptide binding]; other site
544404008763	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
544404008764	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404008765	substrate binding pocket [chemical binding]; other site
544404008766	membrane-bound complex binding site; other site
544404008767	hinge residues; other site
544404008768	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404008769	substrate binding pocket [chemical binding]; other site
544404008770	membrane-bound complex binding site; other site
544404008771	hinge residues; other site
544404008772	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404008773	dimer interface [polypeptide binding]; other site
544404008774	phosphorylation site [posttranslational modification]
544404008775	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404008776	ATP binding site [chemical binding]; other site
544404008777	Mg2+ binding site [ion binding]; other site
544404008778	G-X-G motif; other site
544404008779	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404008780	active site
544404008781	phosphorylation site [posttranslational modification]
544404008782	intermolecular recognition site; other site
544404008783	dimerization interface [polypeptide binding]; other site
544404008784	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
544404008785	putative binding surface; other site
544404008786	active site
544404008787	putative transporter YfdV; Provisional; Region: PRK09903
544404008788	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
544404008789	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
544404008790	PYR/PP interface [polypeptide binding]; other site
544404008791	dimer interface [polypeptide binding]; other site
544404008792	TPP binding site [chemical binding]; other site
544404008793	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
544404008794	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
544404008795	TPP-binding site; other site
544404008796	dimer interface [polypeptide binding]; other site
544404008797	formyl-coenzyme A transferase; Provisional; Region: PRK05398
544404008798	CoA-transferase family III; Region: CoA_transf_3; pfam02515
544404008799	hypothetical protein; Provisional; Region: PRK10316
544404008800	YfdX protein; Region: YfdX; pfam10938
544404008801	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
544404008802	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
544404008803	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
544404008804	putative acyl-acceptor binding pocket; other site
544404008805	aminotransferase; Validated; Region: PRK08175
544404008806	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404008807	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404008808	homodimer interface [polypeptide binding]; other site
544404008809	catalytic residue [active]
544404008810	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
544404008811	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
544404008812	GAF domain; Region: GAF; pfam01590
544404008813	Histidine kinase; Region: His_kinase; pfam06580
544404008814	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404008815	ATP binding site [chemical binding]; other site
544404008816	Mg2+ binding site [ion binding]; other site
544404008817	G-X-G motif; other site
544404008818	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
544404008819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404008820	active site
544404008821	phosphorylation site [posttranslational modification]
544404008822	intermolecular recognition site; other site
544404008823	dimerization interface [polypeptide binding]; other site
544404008824	LytTr DNA-binding domain; Region: LytTR; pfam04397
544404008825	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404008826	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404008827	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
544404008828	dimerization domain swap beta strand [polypeptide binding]; other site
544404008829	regulatory protein interface [polypeptide binding]; other site
544404008830	active site
544404008831	regulatory phosphorylation site [posttranslational modification]; other site
544404008832	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
544404008833	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
544404008834	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
544404008835	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
544404008836	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404008837	active site
544404008838	phosphorylation site [posttranslational modification]
544404008839	exoaminopeptidase; Provisional; Region: PRK09961
544404008840	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
544404008841	oligomer interface [polypeptide binding]; other site
544404008842	active site
544404008843	metal binding site [ion binding]; metal-binding site
544404008844	aminopeptidase; Provisional; Region: PRK09795
544404008845	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
544404008846	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
544404008847	active site
544404008848	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
544404008849	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
544404008850	active site
544404008851	P-loop; other site
544404008852	phosphorylation site [posttranslational modification]
544404008853	glucokinase, proteobacterial type; Region: glk; TIGR00749
544404008854	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404008855	nucleotide binding site [chemical binding]; other site
544404008856	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
544404008857	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
544404008858	Cl- selectivity filter; other site
544404008859	Cl- binding residues [ion binding]; other site
544404008860	pore gating glutamate residue; other site
544404008861	dimer interface [polypeptide binding]; other site
544404008862	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
544404008863	manganese transport protein MntH; Reviewed; Region: PRK00701
544404008864	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
544404008865	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
544404008866	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
544404008867	Nucleoside recognition; Region: Gate; pfam07670
544404008868	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
544404008869	MASE1; Region: MASE1; pfam05231
544404008870	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404008871	diguanylate cyclase; Region: GGDEF; smart00267
544404008872	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404008873	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
544404008874	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404008875	salt bridge; other site
544404008876	non-specific DNA binding site [nucleotide binding]; other site
544404008877	sequence-specific DNA binding site [nucleotide binding]; other site
544404008878	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
544404008879	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
544404008880	Probable transposase; Region: OrfB_IS605; pfam01385
544404008881	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
544404008882	Transposase IS200 like; Region: Y1_Tnp; pfam01797
544404008883	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
544404008884	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
544404008885	active site
544404008886	HIGH motif; other site
544404008887	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
544404008888	active site
544404008889	KMSKS motif; other site
544404008890	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404008891	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404008892	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
544404008893	putative dimerization interface [polypeptide binding]; other site
544404008894	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
544404008895	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
544404008896	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
544404008897	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
544404008898	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
544404008899	nucleotide binding pocket [chemical binding]; other site
544404008900	K-X-D-G motif; other site
544404008901	catalytic site [active]
544404008902	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
544404008903	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
544404008904	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
544404008905	Dimer interface [polypeptide binding]; other site
544404008906	BRCT sequence motif; other site
544404008907	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
544404008908	cell division protein ZipA; Provisional; Region: PRK03427
544404008909	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
544404008910	FtsZ protein binding site [polypeptide binding]; other site
544404008911	putative sulfate transport protein CysZ; Validated; Region: PRK04949
544404008912	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
544404008913	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
544404008914	dimer interface [polypeptide binding]; other site
544404008915	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404008916	catalytic residue [active]
544404008917	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
544404008918	dimerization domain swap beta strand [polypeptide binding]; other site
544404008919	regulatory protein interface [polypeptide binding]; other site
544404008920	active site
544404008921	regulatory phosphorylation site [posttranslational modification]; other site
544404008922	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
544404008923	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
544404008924	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
544404008925	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
544404008926	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
544404008927	HPr interaction site; other site
544404008928	glycerol kinase (GK) interaction site [polypeptide binding]; other site
544404008929	active site
544404008930	phosphorylation site [posttranslational modification]
544404008931	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
544404008932	dimer interface [polypeptide binding]; other site
544404008933	pyridoxamine kinase; Validated; Region: PRK05756
544404008934	pyridoxal binding site [chemical binding]; other site
544404008935	ATP binding site [chemical binding]; other site
544404008936	hypothetical protein; Provisional; Region: PRK10318
544404008937	cysteine synthase B; Region: cysM; TIGR01138
544404008938	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
544404008939	dimer interface [polypeptide binding]; other site
544404008940	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404008941	catalytic residue [active]
544404008942	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
544404008943	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
544404008944	Walker A/P-loop; other site
544404008945	ATP binding site [chemical binding]; other site
544404008946	Q-loop/lid; other site
544404008947	ABC transporter signature motif; other site
544404008948	Walker B; other site
544404008949	D-loop; other site
544404008950	H-loop/switch region; other site
544404008951	TOBE-like domain; Region: TOBE_3; pfam12857
544404008952	sulfate transport protein; Provisional; Region: cysT; CHL00187
544404008953	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404008954	dimer interface [polypeptide binding]; other site
544404008955	conserved gate region; other site
544404008956	putative PBP binding loops; other site
544404008957	ABC-ATPase subunit interface; other site
544404008958	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
544404008959	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404008960	dimer interface [polypeptide binding]; other site
544404008961	conserved gate region; other site
544404008962	putative PBP binding loops; other site
544404008963	ABC-ATPase subunit interface; other site
544404008964	thiosulfate transporter subunit; Provisional; Region: PRK10852
544404008965	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
544404008966	short chain dehydrogenase; Provisional; Region: PRK08226
544404008967	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
544404008968	NAD binding site [chemical binding]; other site
544404008969	homotetramer interface [polypeptide binding]; other site
544404008970	homodimer interface [polypeptide binding]; other site
544404008971	active site
544404008972	transcriptional regulator MurR; Provisional; Region: PRK15482
544404008973	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
544404008974	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
544404008975	putative active site [active]
544404008976	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
544404008977	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
544404008978	putative active site [active]
544404008979	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
544404008980	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404008981	active site turn [active]
544404008982	phosphorylation site [posttranslational modification]
544404008983	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
544404008984	putative periplasmic esterase; Provisional; Region: PRK03642
544404008985	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
544404008986	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
544404008987	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
544404008988	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
544404008989	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
544404008990	putative acetyltransferase; Provisional; Region: PRK03624
544404008991	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404008992	Coenzyme A binding pocket [chemical binding]; other site
544404008993	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
544404008994	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
544404008995	active site
544404008996	metal binding site [ion binding]; metal-binding site
544404008997	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
544404008998	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
544404008999	transcriptional regulator EutR; Provisional; Region: PRK10130
544404009000	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404009001	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404009002	carboxysome structural protein EutK; Provisional; Region: PRK15466
544404009003	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
544404009004	Hexamer interface [polypeptide binding]; other site
544404009005	Hexagonal pore residue; other site
544404009006	FaeA-like protein; Region: FaeA; pfam04703
544404009007	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
544404009008	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
544404009009	putative hexamer interface [polypeptide binding]; other site
544404009010	putative hexagonal pore; other site
544404009011	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
544404009012	putative hexamer interface [polypeptide binding]; other site
544404009013	putative hexagonal pore; other site
544404009014	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
544404009015	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
544404009016	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
544404009017	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
544404009018	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
544404009019	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
544404009020	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
544404009021	active site
544404009022	metal binding site [ion binding]; metal-binding site
544404009023	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
544404009024	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404009025	nucleotide binding site [chemical binding]; other site
544404009026	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
544404009027	putative catalytic cysteine [active]
544404009028	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
544404009029	Hexamer/Pentamer interface [polypeptide binding]; other site
544404009030	central pore; other site
544404009031	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
544404009032	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
544404009033	Hexamer interface [polypeptide binding]; other site
544404009034	Putative hexagonal pore residue; other site
544404009035	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
544404009036	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
544404009037	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
544404009038	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
544404009039	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
544404009040	G1 box; other site
544404009041	GTP/Mg2+ binding site [chemical binding]; other site
544404009042	G2 box; other site
544404009043	Switch I region; other site
544404009044	G3 box; other site
544404009045	Switch II region; other site
544404009046	G4 box; other site
544404009047	G5 box; other site
544404009048	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
544404009049	putative hexamer interface [polypeptide binding]; other site
544404009050	putative hexagonal pore; other site
544404009051	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
544404009052	Malic enzyme, N-terminal domain; Region: malic; pfam00390
544404009053	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
544404009054	putative NAD(P) binding site [chemical binding]; other site
544404009055	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
544404009056	transaldolase-like protein; Provisional; Region: PTZ00411
544404009057	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
544404009058	active site
544404009059	dimer interface [polypeptide binding]; other site
544404009060	catalytic residue [active]
544404009061	transketolase; Reviewed; Region: PRK12753
544404009062	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
544404009063	TPP-binding site [chemical binding]; other site
544404009064	dimer interface [polypeptide binding]; other site
544404009065	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
544404009066	PYR/PP interface [polypeptide binding]; other site
544404009067	dimer interface [polypeptide binding]; other site
544404009068	TPP binding site [chemical binding]; other site
544404009069	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
544404009070	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
544404009071	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
544404009072	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
544404009073	dimer interface [polypeptide binding]; other site
544404009074	ADP-ribose binding site [chemical binding]; other site
544404009075	active site
544404009076	nudix motif; other site
544404009077	metal binding site [ion binding]; metal-binding site
544404009078	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
544404009079	4Fe-4S binding domain; Region: Fer4; pfam00037
544404009080	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404009081	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404009082	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
544404009083	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
544404009084	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404009085	dimerization interface [polypeptide binding]; other site
544404009086	Histidine kinase; Region: HisKA_3; pfam07730
544404009087	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404009088	ATP binding site [chemical binding]; other site
544404009089	Mg2+ binding site [ion binding]; other site
544404009090	G-X-G motif; other site
544404009091	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
544404009092	Protein export membrane protein; Region: SecD_SecF; cl14618
544404009093	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
544404009094	ArsC family; Region: ArsC; pfam03960
544404009095	putative catalytic residues [active]
544404009096	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
544404009097	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
544404009098	metal binding site [ion binding]; metal-binding site
544404009099	dimer interface [polypeptide binding]; other site
544404009100	hypothetical protein; Provisional; Region: PRK13664
544404009101	putative hydrolase; Provisional; Region: PRK11460
544404009102	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
544404009103	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
544404009104	Helicase; Region: Helicase_RecD; pfam05127
544404009105	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
544404009106	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
544404009107	Predicted metalloprotease [General function prediction only]; Region: COG2321
544404009108	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
544404009109	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
544404009110	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
544404009111	ATP binding site [chemical binding]; other site
544404009112	active site
544404009113	substrate binding site [chemical binding]; other site
544404009114	lipoprotein; Provisional; Region: PRK11679
544404009115	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
544404009116	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
544404009117	dihydrodipicolinate synthase; Region: dapA; TIGR00674
544404009118	dimer interface [polypeptide binding]; other site
544404009119	active site
544404009120	catalytic residue [active]
544404009121	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
544404009122	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
544404009123	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
544404009124	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
544404009125	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
544404009126	catalytic triad [active]
544404009127	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
544404009128	4Fe-4S binding domain; Region: Fer4; pfam00037
544404009129	hydrogenase 4 subunit B; Validated; Region: PRK06521
544404009130	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404009131	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
544404009132	NADH dehydrogenase; Region: NADHdh; cl00469
544404009133	hydrogenase 4 subunit D; Validated; Region: PRK06525
544404009134	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404009135	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
544404009136	hydrogenase 4 subunit F; Validated; Region: PRK06458
544404009137	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404009138	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
544404009139	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
544404009140	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
544404009141	hydrogenase 4 subunit H; Validated; Region: PRK08222
544404009142	4Fe-4S binding domain; Region: Fer4; pfam00037
544404009143	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
544404009144	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
544404009145	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
544404009146	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
544404009147	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404009148	Walker A motif; other site
544404009149	ATP binding site [chemical binding]; other site
544404009150	Walker B motif; other site
544404009151	arginine finger; other site
544404009152	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
544404009153	putative formate transporter; Provisional; Region: focB; PRK09713
544404009154	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
544404009155	Domain of unknown function DUF20; Region: UPF0118; pfam01594
544404009156	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
544404009157	Peptidase family M48; Region: Peptidase_M48; cl12018
544404009158	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
544404009159	ArsC family; Region: ArsC; pfam03960
544404009160	catalytic residues [active]
544404009161	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
544404009162	DNA replication initiation factor; Provisional; Region: PRK08084
544404009163	uracil transporter; Provisional; Region: PRK10720
544404009164	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404009165	active site
544404009166	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
544404009167	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
544404009168	dimerization interface [polypeptide binding]; other site
544404009169	putative ATP binding site [chemical binding]; other site
544404009170	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
544404009171	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
544404009172	active site
544404009173	substrate binding site [chemical binding]; other site
544404009174	cosubstrate binding site; other site
544404009175	catalytic site [active]
544404009176	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
544404009177	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
544404009178	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
544404009179	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
544404009180	domain interface [polypeptide binding]; other site
544404009181	active site
544404009182	catalytic site [active]
544404009183	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
544404009184	putative active site [active]
544404009185	catalytic site [active]
544404009186	exopolyphosphatase; Provisional; Region: PRK10854
544404009187	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
544404009188	MASE1; Region: MASE1; pfam05231
544404009189	diguanylate cyclase; Region: GGDEF; smart00267
544404009190	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
544404009191	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404009192	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
544404009193	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
544404009194	GMP synthase; Reviewed; Region: guaA; PRK00074
544404009195	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
544404009196	AMP/PPi binding site [chemical binding]; other site
544404009197	candidate oxyanion hole; other site
544404009198	catalytic triad [active]
544404009199	potential glutamine specificity residues [chemical binding]; other site
544404009200	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
544404009201	ATP Binding subdomain [chemical binding]; other site
544404009202	Ligand Binding sites [chemical binding]; other site
544404009203	Dimerization subdomain; other site
544404009204	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
544404009205	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
544404009206	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
544404009207	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
544404009208	active site
544404009209	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
544404009210	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
544404009211	generic binding surface II; other site
544404009212	generic binding surface I; other site
544404009213	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
544404009214	GTP-binding protein Der; Reviewed; Region: PRK00093
544404009215	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
544404009216	G1 box; other site
544404009217	GTP/Mg2+ binding site [chemical binding]; other site
544404009218	Switch I region; other site
544404009219	G2 box; other site
544404009220	Switch II region; other site
544404009221	G3 box; other site
544404009222	G4 box; other site
544404009223	G5 box; other site
544404009224	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
544404009225	G1 box; other site
544404009226	GTP/Mg2+ binding site [chemical binding]; other site
544404009227	Switch I region; other site
544404009228	G2 box; other site
544404009229	G3 box; other site
544404009230	Switch II region; other site
544404009231	G4 box; other site
544404009232	G5 box; other site
544404009233	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
544404009234	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
544404009235	Trp docking motif [polypeptide binding]; other site
544404009236	active site
544404009237	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
544404009238	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
544404009239	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
544404009240	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
544404009241	dimer interface [polypeptide binding]; other site
544404009242	motif 1; other site
544404009243	active site
544404009244	motif 2; other site
544404009245	motif 3; other site
544404009246	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
544404009247	anticodon binding site; other site
544404009248	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
544404009249	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
544404009250	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
544404009251	cytoskeletal protein RodZ; Provisional; Region: PRK10856
544404009252	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404009253	non-specific DNA binding site [nucleotide binding]; other site
544404009254	salt bridge; other site
544404009255	sequence-specific DNA binding site [nucleotide binding]; other site
544404009256	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
544404009257	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
544404009258	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404009259	FeS/SAM binding site; other site
544404009260	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
544404009261	active site
544404009262	multimer interface [polypeptide binding]; other site
544404009263	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
544404009264	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
544404009265	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
544404009266	4Fe-4S binding domain; Region: Fer4; pfam00037
544404009267	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
544404009268	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
544404009269	putative [Fe4-S4] binding site [ion binding]; other site
544404009270	putative molybdopterin cofactor binding site [chemical binding]; other site
544404009271	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
544404009272	putative molybdopterin cofactor binding site; other site
544404009273	penicillin-binding protein 1C; Provisional; Region: PRK11240
544404009274	Transglycosylase; Region: Transgly; pfam00912
544404009275	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
544404009276	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
544404009277	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
544404009278	MG2 domain; Region: A2M_N; pfam01835
544404009279	Alpha-2-macroglobulin family; Region: A2M; pfam00207
544404009280	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
544404009281	surface patch; other site
544404009282	thioester region; other site
544404009283	specificity defining residues; other site
544404009284	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
544404009285	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
544404009286	active site residue [active]
544404009287	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
544404009288	active site residue [active]
544404009289	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
544404009290	aminopeptidase B; Provisional; Region: PRK05015
544404009291	Peptidase; Region: DUF3663; pfam12404
544404009292	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
544404009293	interface (dimer of trimers) [polypeptide binding]; other site
544404009294	Substrate-binding/catalytic site; other site
544404009295	Zn-binding sites [ion binding]; other site
544404009296	hypothetical protein; Provisional; Region: PRK10721
544404009297	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
544404009298	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404009299	catalytic loop [active]
544404009300	iron binding site [ion binding]; other site
544404009301	chaperone protein HscA; Provisional; Region: hscA; PRK05183
544404009302	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
544404009303	nucleotide binding site [chemical binding]; other site
544404009304	putative NEF/HSP70 interaction site [polypeptide binding]; other site
544404009305	SBD interface [polypeptide binding]; other site
544404009306	co-chaperone HscB; Provisional; Region: hscB; PRK05014
544404009307	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
544404009308	HSP70 interaction site [polypeptide binding]; other site
544404009309	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
544404009310	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
544404009311	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
544404009312	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
544404009313	trimerization site [polypeptide binding]; other site
544404009314	active site
544404009315	cysteine desulfurase; Provisional; Region: PRK14012
544404009316	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
544404009317	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
544404009318	catalytic residue [active]
544404009319	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
544404009320	Rrf2 family protein; Region: rrf2_super; TIGR00738
544404009321	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
544404009322	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
544404009323	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
544404009324	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
544404009325	active site
544404009326	dimerization interface [polypeptide binding]; other site
544404009327	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
544404009328	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
544404009329	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
544404009330	PRD domain; Region: PRD; pfam00874
544404009331	PRD domain; Region: PRD; pfam00874
544404009332	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
544404009333	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404009334	putative substrate translocation pore; other site
544404009335	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
544404009336	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404009337	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
544404009338	putative dimerization interface [polypeptide binding]; other site
544404009339	putative substrate binding pocket [chemical binding]; other site
544404009340	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
544404009341	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
544404009342	iron-sulfur cluster [ion binding]; other site
544404009343	[2Fe-2S] cluster binding site [ion binding]; other site
544404009344	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
544404009345	beta subunit interface [polypeptide binding]; other site
544404009346	alpha subunit interface [polypeptide binding]; other site
544404009347	active site
544404009348	substrate binding site [chemical binding]; other site
544404009349	Fe binding site [ion binding]; other site
544404009350	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
544404009351	inter-subunit interface; other site
544404009352	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
544404009353	[2Fe-2S] cluster binding site [ion binding]; other site
544404009354	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
544404009355	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
544404009356	NAD binding site [chemical binding]; other site
544404009357	active site
544404009358	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
544404009359	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404009360	Predicted membrane protein [Function unknown]; Region: COG2259
544404009361	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
544404009362	active site
544404009363	catalytic residues [active]
544404009364	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404009365	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404009366	TM-ABC transporter signature motif; other site
544404009367	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
544404009368	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404009369	Walker A/P-loop; other site
544404009370	ATP binding site [chemical binding]; other site
544404009371	Q-loop/lid; other site
544404009372	ABC transporter signature motif; other site
544404009373	Walker B; other site
544404009374	D-loop; other site
544404009375	H-loop/switch region; other site
544404009376	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404009377	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
544404009378	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
544404009379	ligand binding site [chemical binding]; other site
544404009380	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404009381	TPR motif; other site
544404009382	Tetratricopeptide repeat; Region: TPR_16; pfam13432
544404009383	binding surface
544404009384	TPR repeat; Region: TPR_11; pfam13414
544404009385	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404009386	TPR motif; other site
544404009387	binding surface
544404009388	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
544404009389	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
544404009390	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404009391	nucleotide binding site [chemical binding]; other site
544404009392	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
544404009393	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
544404009394	dimer interface [polypeptide binding]; other site
544404009395	active site
544404009396	glycine-pyridoxal phosphate binding site [chemical binding]; other site
544404009397	folate binding site [chemical binding]; other site
544404009398	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
544404009399	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
544404009400	heme-binding site [chemical binding]; other site
544404009401	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
544404009402	FAD binding pocket [chemical binding]; other site
544404009403	FAD binding motif [chemical binding]; other site
544404009404	phosphate binding motif [ion binding]; other site
544404009405	beta-alpha-beta structure motif; other site
544404009406	NAD binding pocket [chemical binding]; other site
544404009407	Heme binding  pocket [chemical binding]; other site
544404009408	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
544404009409	Nitrogen regulatory protein P-II; Region: P-II; smart00938
544404009410	response regulator GlrR; Provisional; Region: PRK15115
544404009411	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404009412	active site
544404009413	phosphorylation site [posttranslational modification]
544404009414	intermolecular recognition site; other site
544404009415	dimerization interface [polypeptide binding]; other site
544404009416	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404009417	Walker A motif; other site
544404009418	ATP binding site [chemical binding]; other site
544404009419	Walker B motif; other site
544404009420	arginine finger; other site
544404009421	hypothetical protein; Provisional; Region: PRK10722
544404009422	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
544404009423	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404009424	dimer interface [polypeptide binding]; other site
544404009425	phosphorylation site [posttranslational modification]
544404009426	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404009427	ATP binding site [chemical binding]; other site
544404009428	Mg2+ binding site [ion binding]; other site
544404009429	G-X-G motif; other site
544404009430	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
544404009431	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
544404009432	dimerization interface [polypeptide binding]; other site
544404009433	ATP binding site [chemical binding]; other site
544404009434	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
544404009435	dimerization interface [polypeptide binding]; other site
544404009436	ATP binding site [chemical binding]; other site
544404009437	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
544404009438	putative active site [active]
544404009439	catalytic triad [active]
544404009440	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
544404009441	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404009442	substrate binding pocket [chemical binding]; other site
544404009443	membrane-bound complex binding site; other site
544404009444	hinge residues; other site
544404009445	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404009446	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404009447	catalytic residue [active]
544404009448	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
544404009449	nucleoside/Zn binding site; other site
544404009450	dimer interface [polypeptide binding]; other site
544404009451	catalytic motif [active]
544404009452	hypothetical protein; Provisional; Region: PRK11590
544404009453	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
544404009454	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
544404009455	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
544404009456	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
544404009457	putative active site [active]
544404009458	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
544404009459	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
544404009460	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
544404009461	active site
544404009462	hydrophilic channel; other site
544404009463	dimerization interface [polypeptide binding]; other site
544404009464	catalytic residues [active]
544404009465	active site lid [active]
544404009466	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
544404009467	Recombination protein O N terminal; Region: RecO_N; pfam11967
544404009468	Recombination protein O C terminal; Region: RecO_C; pfam02565
544404009469	GTPase Era; Reviewed; Region: era; PRK00089
544404009470	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
544404009471	G1 box; other site
544404009472	GTP/Mg2+ binding site [chemical binding]; other site
544404009473	Switch I region; other site
544404009474	G2 box; other site
544404009475	Switch II region; other site
544404009476	G3 box; other site
544404009477	G4 box; other site
544404009478	G5 box; other site
544404009479	KH domain; Region: KH_2; pfam07650
544404009480	ribonuclease III; Reviewed; Region: rnc; PRK00102
544404009481	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
544404009482	dimerization interface [polypeptide binding]; other site
544404009483	active site
544404009484	metal binding site [ion binding]; metal-binding site
544404009485	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
544404009486	dsRNA binding site [nucleotide binding]; other site
544404009487	signal peptidase I; Provisional; Region: PRK10861
544404009488	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
544404009489	Catalytic site [active]
544404009490	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
544404009491	GTP-binding protein LepA; Provisional; Region: PRK05433
544404009492	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
544404009493	G1 box; other site
544404009494	putative GEF interaction site [polypeptide binding]; other site
544404009495	GTP/Mg2+ binding site [chemical binding]; other site
544404009496	Switch I region; other site
544404009497	G2 box; other site
544404009498	G3 box; other site
544404009499	Switch II region; other site
544404009500	G4 box; other site
544404009501	G5 box; other site
544404009502	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
544404009503	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
544404009504	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
544404009505	SoxR reducing system protein RseC; Provisional; Region: PRK10862
544404009506	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
544404009507	anti-sigma E factor; Provisional; Region: rseB; PRK09455
544404009508	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
544404009509	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
544404009510	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
544404009511	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
544404009512	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
544404009513	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
544404009514	DNA binding residues [nucleotide binding]
544404009515	L-aspartate oxidase; Provisional; Region: PRK09077
544404009516	L-aspartate oxidase; Provisional; Region: PRK06175
544404009517	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
544404009518	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
544404009519	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404009520	S-adenosylmethionine binding site [chemical binding]; other site
544404009521	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
544404009522	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
544404009523	ATP binding site [chemical binding]; other site
544404009524	Mg++ binding site [ion binding]; other site
544404009525	motif III; other site
544404009526	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404009527	nucleotide binding region [chemical binding]; other site
544404009528	ATP-binding site [chemical binding]; other site
544404009529	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404009530	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404009531	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
544404009532	dimerization interface [polypeptide binding]; other site
544404009533	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
544404009534	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
544404009535	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
544404009536	ligand binding site [chemical binding]; other site
544404009537	active site
544404009538	UGI interface [polypeptide binding]; other site
544404009539	catalytic site [active]
544404009540	putative methyltransferase; Provisional; Region: PRK10864
544404009541	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
544404009542	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
544404009543	thioredoxin 2; Provisional; Region: PRK10996
544404009544	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
544404009545	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
544404009546	catalytic residues [active]
544404009547	Uncharacterized conserved protein [Function unknown]; Region: COG3148
544404009548	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
544404009549	CoA binding domain; Region: CoA_binding_2; pfam13380
544404009550	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
544404009551	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
544404009552	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
544404009553	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
544404009554	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
544404009555	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
544404009556	domain interface [polypeptide binding]; other site
544404009557	putative active site [active]
544404009558	catalytic site [active]
544404009559	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
544404009560	domain interface [polypeptide binding]; other site
544404009561	putative active site [active]
544404009562	catalytic site [active]
544404009563	lipoprotein; Provisional; Region: PRK10759
544404009564	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
544404009565	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404009566	putative substrate translocation pore; other site
544404009567	protein disaggregation chaperone; Provisional; Region: PRK10865
544404009568	Clp amino terminal domain; Region: Clp_N; pfam02861
544404009569	Clp amino terminal domain; Region: Clp_N; pfam02861
544404009570	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404009571	Walker A motif; other site
544404009572	ATP binding site [chemical binding]; other site
544404009573	Walker B motif; other site
544404009574	arginine finger; other site
544404009575	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404009576	Walker A motif; other site
544404009577	ATP binding site [chemical binding]; other site
544404009578	Walker B motif; other site
544404009579	arginine finger; other site
544404009580	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
544404009581	hypothetical protein; Provisional; Region: PRK10723
544404009582	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
544404009583	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
544404009584	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404009585	RNA binding surface [nucleotide binding]; other site
544404009586	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
544404009587	active site
544404009588	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
544404009589	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
544404009590	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
544404009591	30S subunit binding site; other site
544404009592	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
544404009593	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
544404009594	Prephenate dehydratase; Region: PDT; pfam00800
544404009595	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
544404009596	putative L-Phe binding site [chemical binding]; other site
544404009597	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
544404009598	Chorismate mutase type II; Region: CM_2; cl00693
544404009599	prephenate dehydrogenase; Validated; Region: PRK08507
544404009600	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
544404009601	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
544404009602	lipoprotein; Provisional; Region: PRK11443
544404009603	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
544404009604	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
544404009605	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
544404009606	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404009607	metal binding site [ion binding]; metal-binding site
544404009608	active site
544404009609	I-site; other site
544404009610	putative outer membrane lipoprotein; Provisional; Region: PRK09967
544404009611	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404009612	ligand binding site [chemical binding]; other site
544404009613	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
544404009614	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
544404009615	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
544404009616	RimM N-terminal domain; Region: RimM; pfam01782
544404009617	PRC-barrel domain; Region: PRC; pfam05239
544404009618	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
544404009619	signal recognition particle protein; Provisional; Region: PRK10867
544404009620	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
544404009621	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
544404009622	P loop; other site
544404009623	GTP binding site [chemical binding]; other site
544404009624	Signal peptide binding domain; Region: SRP_SPB; pfam02978
544404009625	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
544404009626	Domain of unknown function DUF21; Region: DUF21; pfam01595
544404009627	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
544404009628	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
544404009629	dimer interface [polypeptide binding]; other site
544404009630	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
544404009631	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
544404009632	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
544404009633	recombination and repair protein; Provisional; Region: PRK10869
544404009634	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
544404009635	Walker A/P-loop; other site
544404009636	ATP binding site [chemical binding]; other site
544404009637	Q-loop/lid; other site
544404009638	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
544404009639	Q-loop/lid; other site
544404009640	ABC transporter signature motif; other site
544404009641	Walker B; other site
544404009642	D-loop; other site
544404009643	H-loop/switch region; other site
544404009644	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
544404009645	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
544404009646	hypothetical protein; Validated; Region: PRK01777
544404009647	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
544404009648	putative coenzyme Q binding site [chemical binding]; other site
544404009649	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
544404009650	SmpB-tmRNA interface; other site
544404009651	DinI-like family; Region: DinI; pfam06183
544404009652	IpaB/EvcA family; Region: IpaB_EvcA; pfam03278
544404009653	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404009654	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404009655	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404009656	Transposase; Region: HTH_Tnp_1; cl17663
544404009657	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404009658	putative transposase OrfB; Reviewed; Region: PHA02517
544404009659	HTH-like domain; Region: HTH_21; pfam13276
544404009660	Integrase core domain; Region: rve; pfam00665
544404009661	Integrase core domain; Region: rve_3; pfam13683
544404009662	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404009663	homodimer interface [polypeptide binding]; other site
544404009664	putative GKAP docking site [polypeptide binding]; other site
544404009665	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404009666	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404009667	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404009668	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404009669	Transposase; Region: HTH_Tnp_1; pfam01527
544404009670	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404009671	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
544404009672	catalytic residue [active]
544404009673	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
544404009674	Lysis protein S; Region: Lysis_S; pfam04971
544404009675	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
544404009676	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404009677	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
544404009678	Antitermination protein; Region: Antiterm; pfam03589
544404009679	Antitermination protein; Region: Antiterm; pfam03589
544404009680	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
544404009681	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
544404009682	active site
544404009683	metal binding site [ion binding]; metal-binding site
544404009684	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
544404009685	HNH endonuclease; Region: HNH_3; pfam13392
544404009686	AP2 domain; Region: AP2; pfam00847
544404009687	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
544404009688	DNA-binding interface [nucleotide binding]; DNA binding site
544404009689	Helix-turn-helix domain; Region: HTH_38; pfam13936
544404009690	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
544404009691	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688
544404009692	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
544404009693	active site
544404009694	catalytic residues [active]
544404009695	DNA binding site [nucleotide binding]
544404009696	Int/Topo IB signature motif; other site
544404009697	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
544404009698	active site
544404009699	catalytic residues [active]
544404009700	DNA binding site [nucleotide binding]
544404009701	Int/Topo IB signature motif; other site
544404009702	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
544404009703	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
544404009704	hypothetical protein; Provisional; Region: PRK09945
544404009705	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
544404009706	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
544404009707	Autotransporter beta-domain; Region: Autotransporter; pfam03797
544404009708	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
544404009709	substrate binding pocket [chemical binding]; other site
544404009710	active site
544404009711	iron coordination sites [ion binding]; other site
544404009712	Predicted dehydrogenase [General function prediction only]; Region: COG0579
544404009713	hydroxyglutarate oxidase; Provisional; Region: PRK11728
544404009714	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
544404009715	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
544404009716	tetramerization interface [polypeptide binding]; other site
544404009717	NAD(P) binding site [chemical binding]; other site
544404009718	catalytic residues [active]
544404009719	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
544404009720	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404009721	inhibitor-cofactor binding pocket; inhibition site
544404009722	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404009723	catalytic residue [active]
544404009724	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
544404009725	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
544404009726	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404009727	DNA-binding site [nucleotide binding]; DNA binding site
544404009728	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
544404009729	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
544404009730	bacterial OsmY and nodulation domain; Region: BON; smart00749
544404009731	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404009732	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
544404009733	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404009734	dimerization interface [polypeptide binding]; other site
544404009735	putative DNA binding site [nucleotide binding]; other site
544404009736	Transcriptional regulators [Transcription]; Region: MarR; COG1846
544404009737	putative Zn2+ binding site [ion binding]; other site
544404009738	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
544404009739	active site residue [active]
544404009740	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
544404009741	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
544404009742	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
544404009743	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
544404009744	hypothetical protein; Provisional; Region: PRK10556
544404009745	hypothetical protein; Provisional; Region: PRK10132
544404009746	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
544404009747	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404009748	DNA-binding site [nucleotide binding]; DNA binding site
544404009749	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404009750	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404009751	homodimer interface [polypeptide binding]; other site
544404009752	catalytic residue [active]
544404009753	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
544404009754	Uncharacterized conserved protein [Function unknown]; Region: COG2128
544404009755	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
544404009756	catalytic residues [active]
544404009757	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
544404009758	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
544404009759	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
544404009760	Class I ribonucleotide reductase; Region: RNR_I; cd01679
544404009761	active site
544404009762	dimer interface [polypeptide binding]; other site
544404009763	catalytic residues [active]
544404009764	effector binding site; other site
544404009765	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
544404009766	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
544404009767	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
544404009768	dimer interface [polypeptide binding]; other site
544404009769	putative radical transfer pathway; other site
544404009770	diiron center [ion binding]; other site
544404009771	tyrosyl radical; other site
544404009772	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
544404009773	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
544404009774	Walker A/P-loop; other site
544404009775	ATP binding site [chemical binding]; other site
544404009776	Q-loop/lid; other site
544404009777	ABC transporter signature motif; other site
544404009778	Walker B; other site
544404009779	D-loop; other site
544404009780	H-loop/switch region; other site
544404009781	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
544404009782	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
544404009783	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404009784	dimer interface [polypeptide binding]; other site
544404009785	conserved gate region; other site
544404009786	putative PBP binding loops; other site
544404009787	ABC-ATPase subunit interface; other site
544404009788	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
544404009789	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
544404009790	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
544404009791	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404009792	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
544404009793	putative L-valine exporter; Provisional; Region: PRK10408
544404009794	transcriptional repressor MprA; Provisional; Region: PRK10870
544404009795	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
544404009796	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
544404009797	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404009798	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404009799	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
544404009800	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404009801	putative substrate translocation pore; other site
544404009802	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404009803	S-ribosylhomocysteinase; Provisional; Region: PRK02260
544404009804	glutamate--cysteine ligase; Provisional; Region: PRK02107
544404009805	Predicted membrane protein [Function unknown]; Region: COG1238
544404009806	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
544404009807	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404009808	motif II; other site
544404009809	carbon storage regulator; Provisional; Region: PRK01712
544404009810	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
544404009811	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
544404009812	motif 1; other site
544404009813	active site
544404009814	motif 2; other site
544404009815	motif 3; other site
544404009816	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
544404009817	DHHA1 domain; Region: DHHA1; pfam02272
544404009818	recombination regulator RecX; Reviewed; Region: recX; PRK00117
544404009819	recombinase A; Provisional; Region: recA; PRK09354
544404009820	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
544404009821	hexamer interface [polypeptide binding]; other site
544404009822	Walker A motif; other site
544404009823	ATP binding site [chemical binding]; other site
544404009824	Walker B motif; other site
544404009825	hypothetical protein; Validated; Region: PRK03661
544404009826	Transglycosylase SLT domain; Region: SLT_2; pfam13406
544404009827	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404009828	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404009829	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
544404009830	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
544404009831	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
544404009832	putative NAD(P) binding site [chemical binding]; other site
544404009833	active site
544404009834	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
544404009835	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
544404009836	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
544404009837	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404009838	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
544404009839	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
544404009840	putative active site [active]
544404009841	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
544404009842	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
544404009843	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
544404009844	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404009845	Walker A motif; other site
544404009846	ATP binding site [chemical binding]; other site
544404009847	Walker B motif; other site
544404009848	arginine finger; other site
544404009849	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
544404009850	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
544404009851	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
544404009852	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
544404009853	iron binding site [ion binding]; other site
544404009854	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
544404009855	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404009856	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
544404009857	Acylphosphatase; Region: Acylphosphatase; pfam00708
544404009858	HypF finger; Region: zf-HYPF; pfam07503
544404009859	HypF finger; Region: zf-HYPF; pfam07503
544404009860	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
544404009861	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
544404009862	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
544404009863	Transcriptional regulators [Transcription]; Region: PurR; COG1609
544404009864	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404009865	DNA binding site [nucleotide binding]
544404009866	domain linker motif; other site
544404009867	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
544404009868	dimerization interface (closed form) [polypeptide binding]; other site
544404009869	ligand binding site [chemical binding]; other site
544404009870	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
544404009871	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404009872	active site turn [active]
544404009873	phosphorylation site [posttranslational modification]
544404009874	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
544404009875	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
544404009876	beta-galactosidase; Region: BGL; TIGR03356
544404009877	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
544404009878	nickel binding site [ion binding]; other site
544404009879	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
544404009880	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
544404009881	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
544404009882	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
544404009883	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
544404009884	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
544404009885	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
544404009886	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
544404009887	NADH dehydrogenase; Region: NADHdh; cl00469
544404009888	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
544404009889	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
544404009890	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
544404009891	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
544404009892	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
544404009893	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
544404009894	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
544404009895	hydrogenase assembly chaperone; Provisional; Region: PRK10409
544404009896	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
544404009897	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
544404009898	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
544404009899	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
544404009900	dimerization interface [polypeptide binding]; other site
544404009901	ATP binding site [chemical binding]; other site
544404009902	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
544404009903	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
544404009904	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
544404009905	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404009906	Walker A motif; other site
544404009907	ATP binding site [chemical binding]; other site
544404009908	Walker B motif; other site
544404009909	arginine finger; other site
544404009910	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
544404009911	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
544404009912	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
544404009913	MutS domain I; Region: MutS_I; pfam01624
544404009914	MutS domain II; Region: MutS_II; pfam05188
544404009915	MutS domain III; Region: MutS_III; pfam05192
544404009916	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
544404009917	Walker A/P-loop; other site
544404009918	ATP binding site [chemical binding]; other site
544404009919	Q-loop/lid; other site
544404009920	ABC transporter signature motif; other site
544404009921	Walker B; other site
544404009922	D-loop; other site
544404009923	H-loop/switch region; other site
544404009924	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
544404009925	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
544404009926	active site
544404009927	metal binding site [ion binding]; metal-binding site
544404009928	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
544404009929	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
544404009930	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
544404009931	Flavoprotein; Region: Flavoprotein; pfam02441
544404009932	MarR family; Region: MarR_2; cl17246
544404009933	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
544404009934	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
544404009935	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
544404009936	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
544404009937	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
544404009938	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
544404009939	DNA binding residues [nucleotide binding]
544404009940	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
544404009941	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404009942	Peptidase family M23; Region: Peptidase_M23; pfam01551
544404009943	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
544404009944	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404009945	S-adenosylmethionine binding site [chemical binding]; other site
544404009946	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
544404009947	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
544404009948	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
544404009949	Permutation of conserved domain; other site
544404009950	active site
544404009951	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
544404009952	homotrimer interaction site [polypeptide binding]; other site
544404009953	zinc binding site [ion binding]; other site
544404009954	CDP-binding sites; other site
544404009955	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
544404009956	substrate binding site; other site
544404009957	dimer interface; other site
544404009958	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
544404009959	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
544404009960	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
544404009961	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
544404009962	ligand-binding site [chemical binding]; other site
544404009963	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
544404009964	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
544404009965	CysD dimerization site [polypeptide binding]; other site
544404009966	G1 box; other site
544404009967	putative GEF interaction site [polypeptide binding]; other site
544404009968	GTP/Mg2+ binding site [chemical binding]; other site
544404009969	Switch I region; other site
544404009970	G2 box; other site
544404009971	G3 box; other site
544404009972	Switch II region; other site
544404009973	G4 box; other site
544404009974	G5 box; other site
544404009975	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
544404009976	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
544404009977	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
544404009978	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
544404009979	Active Sites [active]
544404009980	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
544404009981	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
544404009982	metal binding site [ion binding]; metal-binding site
544404009983	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
544404009984	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
544404009985	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
544404009986	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
544404009987	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
544404009988	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
544404009989	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
544404009990	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
544404009991	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
544404009992	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
544404009993	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
544404009994	Hok/gef family; Region: HOK_GEF; pfam01848
544404009995	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
544404009996	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
544404009997	Active Sites [active]
544404009998	sulfite reductase subunit beta; Provisional; Region: PRK13504
544404009999	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
544404010000	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
544404010001	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
544404010002	Flavodoxin; Region: Flavodoxin_1; pfam00258
544404010003	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
544404010004	FAD binding pocket [chemical binding]; other site
544404010005	FAD binding motif [chemical binding]; other site
544404010006	catalytic residues [active]
544404010007	NAD binding pocket [chemical binding]; other site
544404010008	phosphate binding motif [ion binding]; other site
544404010009	beta-alpha-beta structure motif; other site
544404010010	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
544404010011	homohexamer interface [polypeptide binding]; other site
544404010012	putative substrate stabilizing pore; other site
544404010013	pterin binding site; other site
544404010014	putative oxidoreductase FixC; Provisional; Region: PRK10157
544404010015	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
544404010016	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
544404010017	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
544404010018	Ligand binding site [chemical binding]; other site
544404010019	Electron transfer flavoprotein domain; Region: ETF; pfam01012
544404010020	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
544404010021	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
544404010022	FAD binding domain; Region: FAD_binding_4; pfam01565
544404010023	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
544404010024	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
544404010025	NADP binding site [chemical binding]; other site
544404010026	homodimer interface [polypeptide binding]; other site
544404010027	active site
544404010028	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404010029	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010030	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
544404010031	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
544404010032	nucleotide binding site [chemical binding]; other site
544404010033	similar to hypothetical protein
544404010034	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
544404010035	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
544404010036	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
544404010037	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
544404010038	Repair protein; Region: Repair_PSII; pfam04536
544404010039	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
544404010040	Repair protein; Region: Repair_PSII; pfam04536
544404010041	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
544404010042	Repair protein; Region: Repair_PSII; pfam04536
544404010043	enolase; Provisional; Region: eno; PRK00077
544404010044	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
544404010045	dimer interface [polypeptide binding]; other site
544404010046	metal binding site [ion binding]; metal-binding site
544404010047	substrate binding pocket [chemical binding]; other site
544404010048	CTP synthetase; Validated; Region: pyrG; PRK05380
544404010049	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
544404010050	Catalytic site [active]
544404010051	active site
544404010052	UTP binding site [chemical binding]; other site
544404010053	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
544404010054	active site
544404010055	putative oxyanion hole; other site
544404010056	catalytic triad [active]
544404010057	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
544404010058	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
544404010059	homodimer interface [polypeptide binding]; other site
544404010060	metal binding site [ion binding]; metal-binding site
544404010061	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
544404010062	homodimer interface [polypeptide binding]; other site
544404010063	active site
544404010064	putative chemical substrate binding site [chemical binding]; other site
544404010065	metal binding site [ion binding]; metal-binding site
544404010066	toxin MazF; Provisional; Region: PRK09907
544404010067	antitoxin MazE; Provisional; Region: PRK09798
544404010068	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
544404010069	HD domain; Region: HD_4; pfam13328
544404010070	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
544404010071	synthetase active site [active]
544404010072	NTP binding site [chemical binding]; other site
544404010073	metal binding site [ion binding]; metal-binding site
544404010074	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
544404010075	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
544404010076	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
544404010077	TRAM domain; Region: TRAM; pfam01938
544404010078	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404010079	S-adenosylmethionine binding site [chemical binding]; other site
544404010080	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
544404010081	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
544404010082	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404010083	dimerization interface [polypeptide binding]; other site
544404010084	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404010085	dimer interface [polypeptide binding]; other site
544404010086	phosphorylation site [posttranslational modification]
544404010087	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404010088	ATP binding site [chemical binding]; other site
544404010089	Mg2+ binding site [ion binding]; other site
544404010090	G-X-G motif; other site
544404010091	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
544404010092	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404010093	active site
544404010094	phosphorylation site [posttranslational modification]
544404010095	intermolecular recognition site; other site
544404010096	dimerization interface [polypeptide binding]; other site
544404010097	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
544404010098	putative binding surface; other site
544404010099	active site
544404010100	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
544404010101	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
544404010102	active site
544404010103	tetramer interface [polypeptide binding]; other site
544404010104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010105	D-galactonate transporter; Region: 2A0114; TIGR00893
544404010106	putative substrate translocation pore; other site
544404010107	flavodoxin; Provisional; Region: PRK08105
544404010108	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
544404010109	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
544404010110	probable active site [active]
544404010111	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
544404010112	SecY interacting protein Syd; Provisional; Region: PRK04968
544404010113	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
544404010114	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
544404010115	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
544404010116	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
544404010117	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
544404010118	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
544404010119	serine transporter; Region: stp; TIGR00814
544404010120	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
544404010121	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
544404010122	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
544404010123	flap endonuclease-like protein; Provisional; Region: PRK09482
544404010124	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
544404010125	active site
544404010126	metal binding site 1 [ion binding]; metal-binding site
544404010127	putative 5' ssDNA interaction site; other site
544404010128	metal binding site 3; metal-binding site
544404010129	metal binding site 2 [ion binding]; metal-binding site
544404010130	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
544404010131	putative DNA binding site [nucleotide binding]; other site
544404010132	putative metal binding site [ion binding]; other site
544404010133	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
544404010134	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
544404010135	dimer interface [polypeptide binding]; other site
544404010136	active site
544404010137	metal binding site [ion binding]; metal-binding site
544404010138	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
544404010139	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
544404010140	intersubunit interface [polypeptide binding]; other site
544404010141	active site
544404010142	Zn2+ binding site [ion binding]; other site
544404010143	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
544404010144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010145	putative substrate translocation pore; other site
544404010146	L-fucose isomerase; Provisional; Region: fucI; PRK10991
544404010147	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
544404010148	hexamer (dimer of trimers) interface [polypeptide binding]; other site
544404010149	trimer interface [polypeptide binding]; other site
544404010150	substrate binding site [chemical binding]; other site
544404010151	Mn binding site [ion binding]; other site
544404010152	L-fuculokinase; Provisional; Region: PRK10331
544404010153	L-fuculose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_FK; cd07773
544404010154	putative N- and C-terminal domain interface [polypeptide binding]; other site
544404010155	putative active site [active]
544404010156	putative MgATP binding site [chemical binding]; other site
544404010157	putative catalytic site [active]
544404010158	metal binding site [ion binding]; metal-binding site
544404010159	putative carbohydrate binding site [chemical binding]; other site
544404010160	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
544404010161	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
544404010162	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
544404010163	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404010164	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
544404010165	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
544404010166	hypothetical protein; Provisional; Region: PRK10873
544404010167	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
544404010168	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404010169	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
544404010170	dimerization interface [polypeptide binding]; other site
544404010171	substrate binding pocket [chemical binding]; other site
544404010172	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
544404010173	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
544404010174	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
544404010175	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
544404010176	catalytic residue [active]
544404010177	CsdA-binding activator; Provisional; Region: PRK15019
544404010178	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
544404010179	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
544404010180	putative ATP binding site [chemical binding]; other site
544404010181	putative substrate interface [chemical binding]; other site
544404010182	murein transglycosylase A; Provisional; Region: mltA; PRK11162
544404010183	MltA specific insert domain; Region: MltA; pfam03562
544404010184	3D domain; Region: 3D; pfam06725
544404010185	AMIN domain; Region: AMIN; pfam11741
544404010186	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
544404010187	active site
544404010188	metal binding site [ion binding]; metal-binding site
544404010189	N-acetylglutamate synthase; Validated; Region: PRK05279
544404010190	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
544404010191	putative feedback inhibition sensing region; other site
544404010192	putative nucleotide binding site [chemical binding]; other site
544404010193	putative substrate binding site [chemical binding]; other site
544404010194	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404010195	Coenzyme A binding pocket [chemical binding]; other site
544404010196	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
544404010197	AAA domain; Region: AAA_30; pfam13604
544404010198	Family description; Region: UvrD_C_2; pfam13538
544404010199	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
544404010200	protease3; Provisional; Region: PRK15101
544404010201	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
544404010202	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
544404010203	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
544404010204	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
544404010205	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
544404010206	hypothetical protein; Provisional; Region: PRK10332
544404010207	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
544404010208	hypothetical protein; Provisional; Region: PRK11521
544404010209	hypothetical protein; Provisional; Region: PRK10557
544404010210	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
544404010211	hypothetical protein; Provisional; Region: PRK10506
544404010212	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
544404010213	thymidylate synthase; Reviewed; Region: thyA; PRK01827
544404010214	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
544404010215	dimerization interface [polypeptide binding]; other site
544404010216	active site
544404010217	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
544404010218	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
544404010219	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
544404010220	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
544404010221	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
544404010222	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
544404010223	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
544404010224	putative active site [active]
544404010225	Ap4A binding site [chemical binding]; other site
544404010226	nudix motif; other site
544404010227	putative metal binding site [ion binding]; other site
544404010228	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
544404010229	putative DNA-binding cleft [nucleotide binding]; other site
544404010230	putative DNA clevage site; other site
544404010231	molecular lever; other site
544404010232	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
544404010233	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
544404010234	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404010235	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404010236	active site
544404010237	catalytic tetrad [active]
544404010238	lysophospholipid transporter LplT; Provisional; Region: PRK11195
544404010239	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010240	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
544404010241	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
544404010242	putative acyl-acceptor binding pocket; other site
544404010243	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
544404010244	acyl-activating enzyme (AAE) consensus motif; other site
544404010245	putative AMP binding site [chemical binding]; other site
544404010246	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
544404010247	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404010248	DNA binding site [nucleotide binding]
544404010249	domain linker motif; other site
544404010250	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
544404010251	dimerization interface (closed form) [polypeptide binding]; other site
544404010252	ligand binding site [chemical binding]; other site
544404010253	diaminopimelate decarboxylase; Provisional; Region: PRK11165
544404010254	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
544404010255	active site
544404010256	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
544404010257	substrate binding site [chemical binding]; other site
544404010258	catalytic residues [active]
544404010259	dimer interface [polypeptide binding]; other site
544404010260	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
544404010261	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404010262	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
544404010263	putative dimerization interface [polypeptide binding]; other site
544404010264	putative racemase; Provisional; Region: PRK10200
544404010265	aspartate racemase; Region: asp_race; TIGR00035
544404010266	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
544404010267	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010268	putative substrate translocation pore; other site
544404010269	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010270	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
544404010271	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
544404010272	NADP binding site [chemical binding]; other site
544404010273	homodimer interface [polypeptide binding]; other site
544404010274	active site
544404010275	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
544404010276	putative acyltransferase; Provisional; Region: PRK05790
544404010277	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
544404010278	dimer interface [polypeptide binding]; other site
544404010279	active site
544404010280	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
544404010281	serine transporter; Region: stp; TIGR00814
544404010282	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
544404010283	DNA binding residues [nucleotide binding]
544404010284	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
544404010285	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
544404010286	hyperosmolarity resistance protein Ebh, N-terminal domain; Region: hyperosmo_Ebh; TIGR04264
544404010287	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
544404010288	Tetratricopeptide repeat; Region: TPR_3; pfam07720
544404010289	Tetratricopeptide repeat; Region: TPR_3; pfam07720
544404010290	transcriptional regulator; Provisional; Region: PRK11906
544404010291	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404010292	DNA binding site [nucleotide binding]
544404010293	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
544404010294	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404010295	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404010296	catalytic residue [active]
544404010297	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404010298	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404010299	DNA binding residues [nucleotide binding]
544404010300	dimerization interface [polypeptide binding]; other site
544404010301	invasion protein OrgB; Provisional; Region: PRK15322
544404010302	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; pfam09482
544404010303	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
544404010304	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
544404010305	Type III secretion needle MxiH like; Region: MxiH; cl09641
544404010306	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404010307	DNA binding residues [nucleotide binding]
544404010308	dimerization interface [polypeptide binding]; other site
544404010309	type III secretion system protein SpaS; Validated; Region: PRK08156
544404010310	type III secretion system protein SpaQ; Provisional; Region: PRK15333
544404010311	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
544404010312	type III secretion system protein SpaO; Validated; Region: PRK08158
544404010313	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
544404010314	Surface presentation of antigens protein; Region: SPAN; pfam02510
544404010315	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; cl03442
544404010316	ATP synthase SpaL; Validated; Region: PRK08149
544404010317	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
544404010318	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
544404010319	Walker A motif; other site
544404010320	ATP binding site [chemical binding]; other site
544404010321	Walker B motif; other site
544404010322	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
544404010323	type III secretion system protein InvA; Provisional; Region: PRK15337
544404010324	type III secretion system regulator InvE; Provisional; Region: PRK15338
544404010325	HrpJ-like domain; Region: HrpJ; pfam07201
544404010326	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
544404010327	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
544404010328	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
544404010329	transcriptional regulator InvF; Provisional; Region: PRK15340
544404010330	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404010331	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
544404010332	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
544404010333	Peptidase family M23; Region: Peptidase_M23; pfam01551
544404010334	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
544404010335	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
544404010336	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
544404010337	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
544404010338	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
544404010339	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
544404010340	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
544404010341	catalytic loop [active]
544404010342	iron binding site [ion binding]; other site
544404010343	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
544404010344	GAF domain; Region: GAF; cl17456
544404010345	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
544404010346	PAS domain; Region: PAS; smart00091
544404010347	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404010348	Walker A motif; other site
544404010349	ATP binding site [chemical binding]; other site
544404010350	Walker B motif; other site
544404010351	arginine finger; other site
544404010352	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
544404010353	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
544404010354	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
544404010355	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
544404010356	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
544404010357	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
544404010358	catalytic residue [active]
544404010359	peptidase; Reviewed; Region: PRK13004
544404010360	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
544404010361	putative metal binding site [ion binding]; other site
544404010362	putative dimer interface [polypeptide binding]; other site
544404010363	D-hydantoinase; Region: D-hydantoinase; TIGR02033
544404010364	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
544404010365	tetramer interface [polypeptide binding]; other site
544404010366	active site
544404010367	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
544404010368	carbamate kinase; Reviewed; Region: PRK12686
544404010369	putative substrate binding site [chemical binding]; other site
544404010370	homodimer interface [polypeptide binding]; other site
544404010371	nucleotide binding site [chemical binding]; other site
544404010372	nucleotide binding site [chemical binding]; other site
544404010373	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
544404010374	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
544404010375	XdhC Rossmann domain; Region: XdhC_C; pfam13478
544404010376	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
544404010377	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
544404010378	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
544404010379	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
544404010380	Ligand binding site; other site
544404010381	metal-binding site
544404010382	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
544404010383	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
544404010384	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404010385	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
544404010386	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
544404010387	active site
544404010388	putative substrate binding pocket [chemical binding]; other site
544404010389	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
544404010390	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
544404010391	putative hypoxanthine oxidase; Provisional; Region: PRK09800
544404010392	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
544404010393	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; cl03161
544404010394	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
544404010395	uracil-xanthine permease; Region: ncs2; TIGR00801
544404010396	guanine deaminase; Provisional; Region: PRK09228
544404010397	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
544404010398	active site
544404010399	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
544404010400	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
544404010401	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
544404010402	4Fe-4S binding domain; Region: Fer4; pfam00037
544404010403	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
544404010404	xanthine permease; Region: pbuX; TIGR03173
544404010405	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
544404010406	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
544404010407	active site
544404010408	metal binding site [ion binding]; metal-binding site
544404010409	nudix motif; other site
544404010410	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
544404010411	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
544404010412	dimer interface [polypeptide binding]; other site
544404010413	putative anticodon binding site; other site
544404010414	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
544404010415	motif 1; other site
544404010416	active site
544404010417	motif 2; other site
544404010418	motif 3; other site
544404010419	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
544404010420	DHH family; Region: DHH; pfam01368
544404010421	DHHA1 domain; Region: DHHA1; pfam02272
544404010422	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
544404010423	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
544404010424	dimerization domain [polypeptide binding]; other site
544404010425	dimer interface [polypeptide binding]; other site
544404010426	catalytic residues [active]
544404010427	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
544404010428	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
544404010429	active site
544404010430	Int/Topo IB signature motif; other site
544404010431	flavodoxin FldB; Provisional; Region: PRK12359
544404010432	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
544404010433	hypothetical protein; Provisional; Region: PRK10878
544404010434	putative global regulator; Reviewed; Region: PRK09559
544404010435	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
544404010436	hemolysin; Provisional; Region: PRK15087
544404010437	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
544404010438	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
544404010439	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
544404010440	beta-galactosidase; Region: BGL; TIGR03356
544404010441	glycine dehydrogenase; Provisional; Region: PRK05367
544404010442	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
544404010443	tetramer interface [polypeptide binding]; other site
544404010444	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404010445	catalytic residue [active]
544404010446	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
544404010447	tetramer interface [polypeptide binding]; other site
544404010448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404010449	catalytic residue [active]
544404010450	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
544404010451	lipoyl attachment site [posttranslational modification]; other site
544404010452	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
544404010453	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
544404010454	oxidoreductase; Provisional; Region: PRK08013
544404010455	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
544404010456	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
544404010457	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
544404010458	proline aminopeptidase P II; Provisional; Region: PRK10879
544404010459	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
544404010460	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
544404010461	active site
544404010462	hypothetical protein; Reviewed; Region: PRK01736
544404010463	Z-ring-associated protein; Provisional; Region: PRK10972
544404010464	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
544404010465	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
544404010466	similar to hypothetical protein
544404010467	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
544404010468	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
544404010469	ligand binding site [chemical binding]; other site
544404010470	NAD binding site [chemical binding]; other site
544404010471	tetramer interface [polypeptide binding]; other site
544404010472	catalytic site [active]
544404010473	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
544404010474	L-serine binding site [chemical binding]; other site
544404010475	ACT domain interface; other site
544404010476	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
544404010477	tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404010478	active site
544404010479	dimer interface [polypeptide binding]; other site
544404010480	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
544404010481	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404010482	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
544404010483	putative dimerization interface [polypeptide binding]; other site
544404010484	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
544404010485	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
544404010486	active site
544404010487	substrate binding site [chemical binding]; other site
544404010488	coenzyme B12 binding site [chemical binding]; other site
544404010489	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
544404010490	B12 binding site [chemical binding]; other site
544404010491	cobalt ligand [ion binding]; other site
544404010492	membrane ATPase/protein kinase; Provisional; Region: PRK09435
544404010493	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
544404010494	Walker A; other site
544404010495	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
544404010496	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
544404010497	substrate binding site [chemical binding]; other site
544404010498	oxyanion hole (OAH) forming residues; other site
544404010499	trimer interface [polypeptide binding]; other site
544404010500	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
544404010501	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
544404010502	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
544404010503	Uncharacterized conserved protein [Function unknown]; Region: COG2968
544404010504	oxidative stress defense protein; Provisional; Region: PRK11087
544404010505	arginine exporter protein; Provisional; Region: PRK09304
544404010506	mechanosensitive channel MscS; Provisional; Region: PRK10334
544404010507	Mechanosensitive ion channel; Region: MS_channel; pfam00924
544404010508	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
544404010509	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
544404010510	active site
544404010511	intersubunit interface [polypeptide binding]; other site
544404010512	zinc binding site [ion binding]; other site
544404010513	Na+ binding site [ion binding]; other site
544404010514	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
544404010515	Phosphoglycerate kinase; Region: PGK; pfam00162
544404010516	substrate binding site [chemical binding]; other site
544404010517	hinge regions; other site
544404010518	ADP binding site [chemical binding]; other site
544404010519	catalytic site [active]
544404010520	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
544404010521	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
544404010522	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
544404010523	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
544404010524	trimer interface [polypeptide binding]; other site
544404010525	putative Zn binding site [ion binding]; other site
544404010526	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
544404010527	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
544404010528	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
544404010529	Walker A/P-loop; other site
544404010530	ATP binding site [chemical binding]; other site
544404010531	Q-loop/lid; other site
544404010532	ABC transporter signature motif; other site
544404010533	Walker B; other site
544404010534	D-loop; other site
544404010535	H-loop/switch region; other site
544404010536	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
544404010537	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
544404010538	Walker A/P-loop; other site
544404010539	ATP binding site [chemical binding]; other site
544404010540	Q-loop/lid; other site
544404010541	ABC transporter signature motif; other site
544404010542	Walker B; other site
544404010543	D-loop; other site
544404010544	H-loop/switch region; other site
544404010545	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
544404010546	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
544404010547	active site
544404010548	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
544404010549	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
544404010550	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
544404010551	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
544404010552	putative active site [active]
544404010553	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
544404010554	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404010555	putative NAD(P) binding site [chemical binding]; other site
544404010556	catalytic Zn binding site [ion binding]; other site
544404010557	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
544404010558	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
544404010559	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
544404010560	active site
544404010561	P-loop; other site
544404010562	phosphorylation site [posttranslational modification]
544404010563	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404010564	active site
544404010565	phosphorylation site [posttranslational modification]
544404010566	transketolase; Reviewed; Region: PRK12753
544404010567	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
544404010568	TPP-binding site [chemical binding]; other site
544404010569	dimer interface [polypeptide binding]; other site
544404010570	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
544404010571	PYR/PP interface [polypeptide binding]; other site
544404010572	dimer interface [polypeptide binding]; other site
544404010573	TPP binding site [chemical binding]; other site
544404010574	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
544404010575	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
544404010576	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
544404010577	agmatinase; Region: agmatinase; TIGR01230
544404010578	oligomer interface [polypeptide binding]; other site
544404010579	putative active site [active]
544404010580	Mn binding site [ion binding]; other site
544404010581	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
544404010582	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
544404010583	dimer interface [polypeptide binding]; other site
544404010584	active site
544404010585	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
544404010586	catalytic residues [active]
544404010587	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
544404010588	Virulence promoting factor; Region: YqgB; pfam11036
544404010589	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
544404010590	S-adenosylmethionine synthetase; Validated; Region: PRK05250
544404010591	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
544404010592	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
544404010593	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
544404010594	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
544404010595	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010596	putative substrate translocation pore; other site
544404010597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404010598	hypothetical protein; Provisional; Region: PRK04860
544404010599	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
544404010600	DNA-specific endonuclease I; Provisional; Region: PRK15137
544404010601	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
544404010602	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
544404010603	RNA methyltransferase, RsmE family; Region: TIGR00046
544404010604	glutathione synthetase; Provisional; Region: PRK05246
544404010605	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
544404010606	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
544404010607	hypothetical protein; Validated; Region: PRK00228
544404010608	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
544404010609	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
544404010610	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
544404010611	Walker A motif; other site
544404010612	ATP binding site [chemical binding]; other site
544404010613	Walker B motif; other site
544404010614	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
544404010615	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
544404010616	catalytic residue [active]
544404010617	YGGT family; Region: YGGT; pfam02325
544404010618	YGGT family; Region: YGGT; pfam02325
544404010619	hypothetical protein; Validated; Region: PRK05090
544404010620	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
544404010621	active site
544404010622	dimerization interface [polypeptide binding]; other site
544404010623	HemN family oxidoreductase; Provisional; Region: PRK05660
544404010624	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404010625	FeS/SAM binding site; other site
544404010626	HemN C-terminal domain; Region: HemN_C; pfam06969
544404010627	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
544404010628	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
544404010629	homodimer interface [polypeptide binding]; other site
544404010630	active site
544404010631	hypothetical protein; Provisional; Region: PRK10626
544404010632	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
544404010633	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
544404010634	hypothetical protein; Provisional; Region: PRK11702
544404010635	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
544404010636	adenine DNA glycosylase; Provisional; Region: PRK10880
544404010637	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
544404010638	minor groove reading motif; other site
544404010639	helix-hairpin-helix signature motif; other site
544404010640	substrate binding pocket [chemical binding]; other site
544404010641	active site
544404010642	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
544404010643	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
544404010644	DNA binding and oxoG recognition site [nucleotide binding]
544404010645	oxidative damage protection protein; Provisional; Region: PRK05408
544404010646	murein transglycosylase C; Provisional; Region: mltC; PRK11671
544404010647	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
544404010648	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404010649	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404010650	catalytic residue [active]
544404010651	nucleoside transporter; Region: 2A0110; TIGR00889
544404010652	ornithine decarboxylase; Provisional; Region: PRK13578
544404010653	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
544404010654	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
544404010655	homodimer interface [polypeptide binding]; other site
544404010656	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404010657	catalytic residue [active]
544404010658	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
544404010659	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
544404010660	integrase; Provisional; Region: PRK09692
544404010661	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404010662	active site
544404010663	Int/Topo IB signature motif; other site
544404010664	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404010665	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404010666	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
544404010667	Homeodomain-like domain; Region: HTH_23; pfam13384
544404010668	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404010669	Transposase; Region: HTH_Tnp_1; pfam01527
544404010670	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404010671	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404010672	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404010673	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404010674	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404010675	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404010676	Nuclease-related domain; Region: NERD; pfam08378
544404010677	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404010678	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
544404010679	Integrase core domain; Region: rve_3; cl15866
544404010680	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
544404010681	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
544404010682	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
544404010683	type III secretion system protein; Provisional; Region: PRK15384; cl14665
544404010684	Homeodomain-like domain; Region: HTH_23; pfam13384
544404010685	Winged helix-turn helix; Region: HTH_29; pfam13551
544404010686	Homeodomain-like domain; Region: HTH_32; pfam13565
544404010687	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
544404010688	DDE superfamily endonuclease; Region: DDE_3; pfam13358
544404010689	putative transposase OrfB; Reviewed; Region: PHA02517
544404010690	HTH-like domain; Region: HTH_21; pfam13276
544404010691	Integrase core domain; Region: rve; pfam00665
544404010692	Integrase core domain; Region: rve_3; pfam13683
544404010693	Transposase; Region: HTH_Tnp_1; cl17663
544404010694	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404010695	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404010696	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404010697	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404010698	homodimer interface [polypeptide binding]; other site
544404010699	putative GKAP docking site [polypeptide binding]; other site
544404010700	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404010701	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404010702	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404010703	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404010704	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404010705	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404010706	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404010707	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404010708	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404010709	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404010710	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404010711	Integrase core domain; Region: rve_3; cl15866
544404010712	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404010713	Transposase; Region: HTH_Tnp_1; cl17663
544404010714	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
544404010715	Phosphate transporter family; Region: PHO4; cl00396
544404010716	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
544404010717	CHAP domain; Region: CHAP; pfam05257
544404010718	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
544404010719	putative S-transferase; Provisional; Region: PRK11752
544404010720	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
544404010721	C-terminal domain interface [polypeptide binding]; other site
544404010722	GSH binding site (G-site) [chemical binding]; other site
544404010723	dimer interface [polypeptide binding]; other site
544404010724	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
544404010725	dimer interface [polypeptide binding]; other site
544404010726	N-terminal domain interface [polypeptide binding]; other site
544404010727	active site
544404010728	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
544404010729	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
544404010730	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
544404010731	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
544404010732	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
544404010733	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
544404010734	putative substrate-binding site; other site
544404010735	nickel binding site [ion binding]; other site
544404010736	hydrogenase 2 large subunit; Provisional; Region: PRK10467
544404010737	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
544404010738	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
544404010739	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
544404010740	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
544404010741	4Fe-4S binding domain; Region: Fer4_6; pfam12837
544404010742	hydrogenase 2 small subunit; Provisional; Region: PRK10468
544404010743	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
544404010744	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
544404010745	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
544404010746	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
544404010747	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
544404010748	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404010749	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404010750	active site
544404010751	catalytic tetrad [active]
544404010752	hypothetical protein; Provisional; Region: PRK05208
544404010753	oxidoreductase; Provisional; Region: PRK07985
544404010754	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
544404010755	NAD binding site [chemical binding]; other site
544404010756	metal binding site [ion binding]; metal-binding site
544404010757	active site
544404010758	biopolymer transport protein ExbD; Provisional; Region: PRK11267
544404010759	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
544404010760	biopolymer transport protein ExbB; Provisional; Region: PRK10414
544404010761	cystathionine beta-lyase; Provisional; Region: PRK08114
544404010762	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
544404010763	homodimer interface [polypeptide binding]; other site
544404010764	substrate-cofactor binding pocket; other site
544404010765	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404010766	catalytic residue [active]
544404010767	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
544404010768	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
544404010769	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
544404010770	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
544404010771	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404010772	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404010773	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
544404010774	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
544404010775	dimer interface [polypeptide binding]; other site
544404010776	active site
544404010777	metal binding site [ion binding]; metal-binding site
544404010778	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
544404010779	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
544404010780	active site
544404010781	catalytic tetrad [active]
544404010782	putative outer membrane lipoprotein; Provisional; Region: PRK09973
544404010783	hypothetical protein; Provisional; Region: PRK01254
544404010784	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
544404010785	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
544404010786	FtsI repressor; Provisional; Region: PRK10883
544404010787	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
544404010788	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
544404010789	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
544404010790	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
544404010791	putative acyl-acceptor binding pocket; other site
544404010792	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
544404010793	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
544404010794	CAP-like domain; other site
544404010795	active site
544404010796	primary dimer interface [polypeptide binding]; other site
544404010797	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
544404010798	putative ABC transporter periplasmic-binding protein; Provisional; Region: PRK09755
544404010799	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
544404010800	peptide binding site [polypeptide binding]; other site
544404010801	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
544404010802	TIGR00156 family protein; Region: TIGR00156
544404010803	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
544404010804	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404010805	active site
544404010806	phosphorylation site [posttranslational modification]
544404010807	intermolecular recognition site; other site
544404010808	dimerization interface [polypeptide binding]; other site
544404010809	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404010810	DNA binding site [nucleotide binding]
544404010811	sensor protein QseC; Provisional; Region: PRK10337
544404010812	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404010813	dimer interface [polypeptide binding]; other site
544404010814	phosphorylation site [posttranslational modification]
544404010815	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404010816	ATP binding site [chemical binding]; other site
544404010817	Mg2+ binding site [ion binding]; other site
544404010818	G-X-G motif; other site
544404010819	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
544404010820	Uncharacterized conserved protein [Function unknown]; Region: COG1359
544404010821	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
544404010822	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
544404010823	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cd04795
544404010824	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
544404010825	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
544404010826	siderophore binding site; other site
544404010827	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
544404010828	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404010829	ABC-ATPase subunit  interface; other site
544404010830	dimer interface [polypeptide binding]; other site
544404010831	putative PBP binding regions; other site
544404010832	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
544404010833	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404010834	dimer interface [polypeptide binding]; other site
544404010835	putative PBP binding regions; other site
544404010836	ABC-ATPase subunit  interface; other site
544404010837	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
544404010838	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
544404010839	Walker A/P-loop; other site
544404010840	ATP binding site [chemical binding]; other site
544404010841	Q-loop/lid; other site
544404010842	ABC transporter signature motif; other site
544404010843	Walker B; other site
544404010844	D-loop; other site
544404010845	H-loop/switch region; other site
544404010846	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
544404010847	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404010848	N-terminal plug; other site
544404010849	ligand-binding site [chemical binding]; other site
544404010850	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
544404010851	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404010852	ATP binding site [chemical binding]; other site
544404010853	Mg2+ binding site [ion binding]; other site
544404010854	G-X-G motif; other site
544404010855	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
544404010856	anchoring element; other site
544404010857	dimer interface [polypeptide binding]; other site
544404010858	ATP binding site [chemical binding]; other site
544404010859	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
544404010860	active site
544404010861	metal binding site [ion binding]; metal-binding site
544404010862	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
544404010863	esterase YqiA; Provisional; Region: PRK11071
544404010864	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
544404010865	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
544404010866	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
544404010867	active site
544404010868	metal binding site [ion binding]; metal-binding site
544404010869	hexamer interface [polypeptide binding]; other site
544404010870	putative dehydrogenase; Provisional; Region: PRK11039
544404010871	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
544404010872	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
544404010873	dimer interface [polypeptide binding]; other site
544404010874	ADP-ribose binding site [chemical binding]; other site
544404010875	active site
544404010876	nudix motif; other site
544404010877	metal binding site [ion binding]; metal-binding site
544404010878	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
544404010879	hypothetical protein; Provisional; Region: PRK11653
544404010880	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
544404010881	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
544404010882	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
544404010883	putative active site [active]
544404010884	metal binding site [ion binding]; metal-binding site
544404010885	zinc transporter ZupT; Provisional; Region: PRK04201
544404010886	ZIP Zinc transporter; Region: Zip; pfam02535
544404010887	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
544404010888	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
544404010889	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
544404010890	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
544404010891	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
544404010892	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
544404010893	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
544404010894	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
544404010895	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
544404010896	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
544404010897	putative ribose interaction site [chemical binding]; other site
544404010898	putative ADP binding site [chemical binding]; other site
544404010899	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
544404010900	active site
544404010901	nucleotide binding site [chemical binding]; other site
544404010902	HIGH motif; other site
544404010903	KMSKS motif; other site
544404010904	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
544404010905	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
544404010906	metal binding triad; other site
544404010907	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
544404010908	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
544404010909	metal binding triad; other site
544404010910	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
544404010911	Uncharacterized conserved protein [Function unknown]; Region: COG3025
544404010912	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
544404010913	putative active site [active]
544404010914	putative metal binding residues [ion binding]; other site
544404010915	signature motif; other site
544404010916	putative triphosphate binding site [ion binding]; other site
544404010917	CHAD domain; Region: CHAD; pfam05235
544404010918	SH3 domain-containing protein; Provisional; Region: PRK10884
544404010919	Bacterial SH3 domain homologues; Region: SH3b; smart00287
544404010920	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
544404010921	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
544404010922	active site
544404010923	NTP binding site [chemical binding]; other site
544404010924	metal binding triad [ion binding]; metal-binding site
544404010925	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
544404010926	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
544404010927	Zn2+ binding site [ion binding]; other site
544404010928	Mg2+ binding site [ion binding]; other site
544404010929	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
544404010930	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
544404010931	homooctamer interface [polypeptide binding]; other site
544404010932	active site
544404010933	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
544404010934	transcriptional activator TtdR; Provisional; Region: PRK09801
544404010935	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404010936	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
544404010937	putative effector binding pocket; other site
544404010938	putative dimerization interface [polypeptide binding]; other site
544404010939	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
544404010940	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
544404010941	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
544404010942	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
544404010943	transmembrane helices; other site
544404010944	UGMP family protein; Validated; Region: PRK09604
544404010945	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
544404010946	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
544404010947	DNA primase; Validated; Region: dnaG; PRK05667
544404010948	CHC2 zinc finger; Region: zf-CHC2; pfam01807
544404010949	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
544404010950	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
544404010951	active site
544404010952	metal binding site [ion binding]; metal-binding site
544404010953	interdomain interaction site; other site
544404010954	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
544404010955	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
544404010956	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
544404010957	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
544404010958	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
544404010959	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
544404010960	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
544404010961	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
544404010962	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
544404010963	DNA binding residues [nucleotide binding]
544404010964	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
544404010965	active site
544404010966	SUMO-1 interface [polypeptide binding]; other site
544404010967	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
544404010968	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
544404010969	FAD binding pocket [chemical binding]; other site
544404010970	FAD binding motif [chemical binding]; other site
544404010971	phosphate binding motif [ion binding]; other site
544404010972	NAD binding pocket [chemical binding]; other site
544404010973	Predicted transcriptional regulators [Transcription]; Region: COG1695
544404010974	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
544404010975	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404010976	PAS fold; Region: PAS_3; pfam08447
544404010977	putative active site [active]
544404010978	heme pocket [chemical binding]; other site
544404010979	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
544404010980	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
544404010981	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
544404010982	dimer interface [polypeptide binding]; other site
544404010983	putative CheW interface [polypeptide binding]; other site
544404010984	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
544404010985	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404010986	inhibitor-cofactor binding pocket; inhibition site
544404010987	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404010988	catalytic residue [active]
544404010989	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
544404010990	dimer interface [polypeptide binding]; other site
544404010991	putative tRNA-binding site [nucleotide binding]; other site
544404010992	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
544404010993	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404010994	DNA binding site [nucleotide binding]
544404010995	domain linker motif; other site
544404010996	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
544404010997	putative dimerization interface [polypeptide binding]; other site
544404010998	putative ligand binding site [chemical binding]; other site
544404010999	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
544404011000	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
544404011001	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
544404011002	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
544404011003	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
544404011004	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
544404011005	inner membrane transporter YjeM; Provisional; Region: PRK15238
544404011006	alpha-glucosidase; Provisional; Region: PRK10137
544404011007	Protein of unknown function, DUF608; Region: DUF608; pfam04685
544404011008	Trehalase; Region: Trehalase; cl17346
544404011009	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
544404011010	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
544404011011	active site
544404011012	FMN binding site [chemical binding]; other site
544404011013	2,4-decadienoyl-CoA binding site; other site
544404011014	catalytic residue [active]
544404011015	4Fe-4S cluster binding site [ion binding]; other site
544404011016	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
544404011017	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404011018	non-specific DNA binding site [nucleotide binding]; other site
544404011019	salt bridge; other site
544404011020	sequence-specific DNA binding site [nucleotide binding]; other site
544404011021	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
544404011022	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
544404011023	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404011024	S-adenosylmethionine binding site [chemical binding]; other site
544404011025	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
544404011026	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
544404011027	putative active site [active]
544404011028	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
544404011029	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
544404011030	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
544404011031	serine/threonine transporter SstT; Provisional; Region: PRK13628
544404011032	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
544404011033	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
544404011034	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
544404011035	galactarate dehydratase; Region: galactar-dH20; TIGR03248
544404011036	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
544404011037	Glucuronate isomerase; Region: UxaC; pfam02614
544404011038	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
544404011039	D-galactonate transporter; Region: 2A0114; TIGR00893
544404011040	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404011041	putative substrate translocation pore; other site
544404011042	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
544404011043	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404011044	DNA-binding site [nucleotide binding]; DNA binding site
544404011045	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
544404011046	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
544404011047	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
544404011048	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
544404011049	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
544404011050	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
544404011051	Predicted membrane protein [Function unknown]; Region: COG5393
544404011052	YqjK-like protein; Region: YqjK; pfam13997
544404011053	Predicted membrane protein [Function unknown]; Region: COG2259
544404011054	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
544404011055	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
544404011056	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
544404011057	putative dimer interface [polypeptide binding]; other site
544404011058	N-terminal domain interface [polypeptide binding]; other site
544404011059	putative substrate binding pocket (H-site) [chemical binding]; other site
544404011060	Predicted membrane protein [Function unknown]; Region: COG3152
544404011061	Predicted membrane protein [Function unknown]; Region: COG3152
544404011062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404011063	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
544404011064	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404011065	dimerization interface [polypeptide binding]; other site
544404011066	Pirin-related protein [General function prediction only]; Region: COG1741
544404011067	Pirin; Region: Pirin; pfam02678
544404011068	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
544404011069	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
544404011070	serine transporter; Region: stp; TIGR00814
544404011071	L-serine dehydratase TdcG; Provisional; Region: PRK15040
544404011072	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
544404011073	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
544404011074	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
544404011075	homotrimer interaction site [polypeptide binding]; other site
544404011076	putative active site [active]
544404011077	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
544404011078	Pyruvate formate lyase 1; Region: PFL1; cd01678
544404011079	coenzyme A binding site [chemical binding]; other site
544404011080	active site
544404011081	catalytic residues [active]
544404011082	glycine loop; other site
544404011083	propionate/acetate kinase; Provisional; Region: PRK12379
544404011084	Acetokinase family; Region: Acetate_kinase; cl17229
544404011085	threonine/serine transporter TdcC; Provisional; Region: PRK13629
544404011086	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
544404011087	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
544404011088	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
544404011089	tetramer interface [polypeptide binding]; other site
544404011090	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404011091	catalytic residue [active]
544404011092	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
544404011093	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404011094	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
544404011095	putative substrate binding pocket [chemical binding]; other site
544404011096	putative dimerization interface [polypeptide binding]; other site
544404011097	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
544404011098	hypothetical protein; Provisional; Region: PRK09716
544404011099	glycerate kinase I; Provisional; Region: PRK10342
544404011100	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
544404011101	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
544404011102	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
544404011103	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404011104	D-galactonate transporter; Region: 2A0114; TIGR00893
544404011105	putative substrate translocation pore; other site
544404011106	galactarate dehydratase; Region: galactar-dH20; TIGR03248
544404011107	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
544404011108	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
544404011109	putative regulator PrlF; Provisional; Region: PRK09974
544404011110	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
544404011111	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
544404011112	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
544404011113	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
544404011114	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404011115	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
544404011116	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
544404011117	active site
544404011118	phosphorylation site [posttranslational modification]
544404011119	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
544404011120	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
544404011121	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
544404011122	active pocket/dimerization site; other site
544404011123	active site
544404011124	phosphorylation site [posttranslational modification]
544404011125	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
544404011126	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
544404011127	active site
544404011128	dimer interface [polypeptide binding]; other site
544404011129	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
544404011130	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
544404011131	dimer interface [polypeptide binding]; other site
544404011132	active site
544404011133	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
544404011134	putative active site [active]
544404011135	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
544404011136	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
544404011137	active site
544404011138	intersubunit interface [polypeptide binding]; other site
544404011139	zinc binding site [ion binding]; other site
544404011140	Na+ binding site [ion binding]; other site
544404011141	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
544404011142	active site
544404011143	phosphorylation site [posttranslational modification]
544404011144	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
544404011145	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
544404011146	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404011147	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
544404011148	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404011149	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404011150	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
544404011151	PapC N-terminal domain; Region: PapC_N; pfam13954
544404011152	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404011153	PapC C-terminal domain; Region: PapC_C; pfam13953
544404011154	Fimbrial protein; Region: Fimbrial; pfam00419
544404011155	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
544404011156	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
544404011157	putative SAM binding site [chemical binding]; other site
544404011158	putative homodimer interface [polypeptide binding]; other site
544404011159	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
544404011160	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
544404011161	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
544404011162	putative ligand binding site [chemical binding]; other site
544404011163	TIGR00252 family protein; Region: TIGR00252
544404011164	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
544404011165	dimer interface [polypeptide binding]; other site
544404011166	active site
544404011167	outer membrane lipoprotein; Provisional; Region: PRK11023
544404011168	BON domain; Region: BON; pfam04972
544404011169	BON domain; Region: BON; pfam04972
544404011170	Predicted permease; Region: DUF318; pfam03773
544404011171	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
544404011172	NADH(P)-binding; Region: NAD_binding_10; pfam13460
544404011173	NAD binding site [chemical binding]; other site
544404011174	active site
544404011175	intracellular protease, PfpI family; Region: PfpI; TIGR01382
544404011176	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
544404011177	proposed catalytic triad [active]
544404011178	conserved cys residue [active]
544404011179	hypothetical protein; Provisional; Region: PRK03467
544404011180	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
544404011181	GIY-YIG motif/motif A; other site
544404011182	putative active site [active]
544404011183	putative metal binding site [ion binding]; other site
544404011184	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
544404011185	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404011186	Coenzyme A binding pocket [chemical binding]; other site
544404011187	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
544404011188	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
544404011189	Peptidase family U32; Region: Peptidase_U32; pfam01136
544404011190	putative protease; Provisional; Region: PRK15447
544404011191	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
544404011192	hypothetical protein; Provisional; Region: PRK10508
544404011193	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
544404011194	tryptophan permease; Provisional; Region: PRK10483
544404011195	aromatic amino acid transport protein; Region: araaP; TIGR00837
544404011196	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
544404011197	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
544404011198	ATP binding site [chemical binding]; other site
544404011199	Mg++ binding site [ion binding]; other site
544404011200	motif III; other site
544404011201	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404011202	nucleotide binding region [chemical binding]; other site
544404011203	ATP-binding site [chemical binding]; other site
544404011204	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
544404011205	putative RNA binding site [nucleotide binding]; other site
544404011206	lipoprotein NlpI; Provisional; Region: PRK11189
544404011207	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404011208	binding surface
544404011209	TPR motif; other site
544404011210	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
544404011211	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
544404011212	RNase E interface [polypeptide binding]; other site
544404011213	trimer interface [polypeptide binding]; other site
544404011214	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
544404011215	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
544404011216	RNase E interface [polypeptide binding]; other site
544404011217	trimer interface [polypeptide binding]; other site
544404011218	active site
544404011219	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
544404011220	putative nucleic acid binding region [nucleotide binding]; other site
544404011221	G-X-X-G motif; other site
544404011222	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
544404011223	RNA binding site [nucleotide binding]; other site
544404011224	domain interface; other site
544404011225	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
544404011226	16S/18S rRNA binding site [nucleotide binding]; other site
544404011227	S13e-L30e interaction site [polypeptide binding]; other site
544404011228	25S rRNA binding site [nucleotide binding]; other site
544404011229	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
544404011230	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
544404011231	RNA binding site [nucleotide binding]; other site
544404011232	active site
544404011233	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
544404011234	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
544404011235	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
544404011236	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
544404011237	translation initiation factor IF-2; Region: IF-2; TIGR00487
544404011238	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
544404011239	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
544404011240	G1 box; other site
544404011241	putative GEF interaction site [polypeptide binding]; other site
544404011242	GTP/Mg2+ binding site [chemical binding]; other site
544404011243	Switch I region; other site
544404011244	G2 box; other site
544404011245	G3 box; other site
544404011246	Switch II region; other site
544404011247	G4 box; other site
544404011248	G5 box; other site
544404011249	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
544404011250	Translation-initiation factor 2; Region: IF-2; pfam11987
544404011251	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
544404011252	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
544404011253	NusA N-terminal domain; Region: NusA_N; pfam08529
544404011254	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
544404011255	RNA binding site [nucleotide binding]; other site
544404011256	homodimer interface [polypeptide binding]; other site
544404011257	NusA-like KH domain; Region: KH_5; pfam13184
544404011258	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
544404011259	G-X-X-G motif; other site
544404011260	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
544404011261	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
544404011262	ribosome maturation protein RimP; Reviewed; Region: PRK00092
544404011263	Sm and related proteins; Region: Sm_like; cl00259
544404011264	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
544404011265	putative oligomer interface [polypeptide binding]; other site
544404011266	putative RNA binding site [nucleotide binding]; other site
544404011267	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
544404011268	ANP binding site [chemical binding]; other site
544404011269	Substrate Binding Site II [chemical binding]; other site
544404011270	Substrate Binding Site I [chemical binding]; other site
544404011271	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
544404011272	Sulfatase; Region: Sulfatase; pfam00884
544404011273	Preprotein translocase SecG subunit; Region: SecG; pfam03840
544404011274	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
544404011275	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
544404011276	active site
544404011277	substrate binding site [chemical binding]; other site
544404011278	metal binding site [ion binding]; metal-binding site
544404011279	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
544404011280	dihydropteroate synthase; Region: DHPS; TIGR01496
544404011281	substrate binding pocket [chemical binding]; other site
544404011282	dimer interface [polypeptide binding]; other site
544404011283	inhibitor binding site; inhibition site
544404011284	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
544404011285	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404011286	Walker A motif; other site
544404011287	ATP binding site [chemical binding]; other site
544404011288	Walker B motif; other site
544404011289	arginine finger; other site
544404011290	Peptidase family M41; Region: Peptidase_M41; pfam01434
544404011291	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
544404011292	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404011293	S-adenosylmethionine binding site [chemical binding]; other site
544404011294	RNA-binding protein YhbY; Provisional; Region: PRK10343
544404011295	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
544404011296	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
544404011297	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
544404011298	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
544404011299	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
544404011300	GTPase CgtA; Reviewed; Region: obgE; PRK12298
544404011301	GTP1/OBG; Region: GTP1_OBG; pfam01018
544404011302	Obg GTPase; Region: Obg; cd01898
544404011303	G1 box; other site
544404011304	GTP/Mg2+ binding site [chemical binding]; other site
544404011305	Switch I region; other site
544404011306	G2 box; other site
544404011307	G3 box; other site
544404011308	Switch II region; other site
544404011309	G4 box; other site
544404011310	G5 box; other site
544404011311	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
544404011312	EamA-like transporter family; Region: EamA; pfam00892
544404011313	EamA-like transporter family; Region: EamA; pfam00892
544404011314	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
544404011315	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
544404011316	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
544404011317	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
544404011318	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
544404011319	substrate binding pocket [chemical binding]; other site
544404011320	chain length determination region; other site
544404011321	substrate-Mg2+ binding site; other site
544404011322	catalytic residues [active]
544404011323	aspartate-rich region 1; other site
544404011324	active site lid residues [active]
544404011325	aspartate-rich region 2; other site
544404011326	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
544404011327	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
544404011328	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
544404011329	hinge; other site
544404011330	active site
544404011331	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
544404011332	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
544404011333	anti sigma factor interaction site; other site
544404011334	regulatory phosphorylation site [posttranslational modification]; other site
544404011335	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
544404011336	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
544404011337	mce related protein; Region: MCE; pfam02470
544404011338	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
544404011339	conserved hypothetical integral membrane protein; Region: TIGR00056
544404011340	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
544404011341	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
544404011342	Walker A/P-loop; other site
544404011343	ATP binding site [chemical binding]; other site
544404011344	Q-loop/lid; other site
544404011345	ABC transporter signature motif; other site
544404011346	Walker B; other site
544404011347	D-loop; other site
544404011348	H-loop/switch region; other site
544404011349	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
544404011350	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
544404011351	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
544404011352	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
544404011353	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
544404011354	putative active site [active]
544404011355	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
544404011356	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
544404011357	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
544404011358	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
544404011359	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
544404011360	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
544404011361	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
544404011362	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
544404011363	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
544404011364	Walker A/P-loop; other site
544404011365	ATP binding site [chemical binding]; other site
544404011366	Q-loop/lid; other site
544404011367	ABC transporter signature motif; other site
544404011368	Walker B; other site
544404011369	D-loop; other site
544404011370	H-loop/switch region; other site
544404011371	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
544404011372	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
544404011373	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
544404011374	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
544404011375	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
544404011376	30S subunit binding site; other site
544404011377	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404011378	active site
544404011379	phosphorylation site [posttranslational modification]
544404011380	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
544404011381	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
544404011382	dimerization domain swap beta strand [polypeptide binding]; other site
544404011383	regulatory protein interface [polypeptide binding]; other site
544404011384	active site
544404011385	regulatory phosphorylation site [posttranslational modification]; other site
544404011386	hypothetical protein; Provisional; Region: PRK10345
544404011387	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
544404011388	Transglycosylase; Region: Transgly; cl17702
544404011389	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
544404011390	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
544404011391	conserved cys residue [active]
544404011392	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
544404011393	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404011394	putative active site [active]
544404011395	heme pocket [chemical binding]; other site
544404011396	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404011397	dimer interface [polypeptide binding]; other site
544404011398	phosphorylation site [posttranslational modification]
544404011399	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404011400	ATP binding site [chemical binding]; other site
544404011401	Mg2+ binding site [ion binding]; other site
544404011402	G-X-G motif; other site
544404011403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404011404	active site
544404011405	phosphorylation site [posttranslational modification]
544404011406	intermolecular recognition site; other site
544404011407	dimerization interface [polypeptide binding]; other site
544404011408	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
544404011409	putative binding surface; other site
544404011410	active site
544404011411	radical SAM protein, TIGR01212 family; Region: TIGR01212
544404011412	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404011413	FeS/SAM binding site; other site
544404011414	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
544404011415	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
544404011416	active site
544404011417	dimer interface [polypeptide binding]; other site
544404011418	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
544404011419	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
544404011420	active site
544404011421	FMN binding site [chemical binding]; other site
544404011422	substrate binding site [chemical binding]; other site
544404011423	3Fe-4S cluster binding site [ion binding]; other site
544404011424	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
544404011425	domain interface; other site
544404011426	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
544404011427	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404011428	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404011429	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
544404011430	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
544404011431	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
544404011432	N-acetylmannosamine kinase; Provisional; Region: PRK05082
544404011433	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
544404011434	nucleotide binding site [chemical binding]; other site
544404011435	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
544404011436	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
544404011437	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
544404011438	putative active site cavity [active]
544404011439	putative sialic acid transporter; Provisional; Region: PRK03893
544404011440	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404011441	putative substrate translocation pore; other site
544404011442	N-acetylneuraminate lyase; Region: nanA; TIGR00683
544404011443	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
544404011444	inhibitor site; inhibition site
544404011445	active site
544404011446	dimer interface [polypeptide binding]; other site
544404011447	catalytic residue [active]
544404011448	transcriptional regulator NanR; Provisional; Region: PRK03837
544404011449	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404011450	DNA-binding site [nucleotide binding]; DNA binding site
544404011451	FCD domain; Region: FCD; pfam07729
544404011452	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
544404011453	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
544404011454	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
544404011455	stringent starvation protein A; Provisional; Region: sspA; PRK09481
544404011456	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
544404011457	C-terminal domain interface [polypeptide binding]; other site
544404011458	putative GSH binding site (G-site) [chemical binding]; other site
544404011459	dimer interface [polypeptide binding]; other site
544404011460	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
544404011461	dimer interface [polypeptide binding]; other site
544404011462	N-terminal domain interface [polypeptide binding]; other site
544404011463	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
544404011464	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
544404011465	23S rRNA interface [nucleotide binding]; other site
544404011466	L3 interface [polypeptide binding]; other site
544404011467	Predicted ATPase [General function prediction only]; Region: COG1485
544404011468	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
544404011469	hypothetical protein; Provisional; Region: PRK11677
544404011470	serine endoprotease; Provisional; Region: PRK10139
544404011471	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
544404011472	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
544404011473	protein binding site [polypeptide binding]; other site
544404011474	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
544404011475	serine endoprotease; Provisional; Region: PRK10898
544404011476	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
544404011477	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
544404011478	malate dehydrogenase; Provisional; Region: PRK05086
544404011479	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
544404011480	NAD binding site [chemical binding]; other site
544404011481	dimerization interface [polypeptide binding]; other site
544404011482	Substrate binding site [chemical binding]; other site
544404011483	arginine repressor; Provisional; Region: PRK05066
544404011484	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
544404011485	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
544404011486	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404011487	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
544404011488	RNAase interaction site [polypeptide binding]; other site
544404011489	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
544404011490	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
544404011491	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
544404011492	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404011493	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404011494	efflux system membrane protein; Provisional; Region: PRK11594
544404011495	transcriptional regulator; Provisional; Region: PRK10632
544404011496	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404011497	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
544404011498	putative effector binding pocket; other site
544404011499	dimerization interface [polypeptide binding]; other site
544404011500	protease TldD; Provisional; Region: tldD; PRK10735
544404011501	hypothetical protein; Provisional; Region: PRK10899
544404011502	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
544404011503	ribonuclease G; Provisional; Region: PRK11712
544404011504	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
544404011505	homodimer interface [polypeptide binding]; other site
544404011506	oligonucleotide binding site [chemical binding]; other site
544404011507	Maf-like protein; Region: Maf; pfam02545
544404011508	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
544404011509	active site
544404011510	dimer interface [polypeptide binding]; other site
544404011511	rod shape-determining protein MreD; Provisional; Region: PRK11060
544404011512	rod shape-determining protein MreC; Region: mreC; TIGR00219
544404011513	rod shape-determining protein MreC; Region: MreC; pfam04085
544404011514	rod shape-determining protein MreB; Provisional; Region: PRK13927
544404011515	MreB and similar proteins; Region: MreB_like; cd10225
544404011516	nucleotide binding site [chemical binding]; other site
544404011517	Mg binding site [ion binding]; other site
544404011518	putative protofilament interaction site [polypeptide binding]; other site
544404011519	RodZ interaction site [polypeptide binding]; other site
544404011520	regulatory protein CsrD; Provisional; Region: PRK11059
544404011521	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404011522	metal binding site [ion binding]; metal-binding site
544404011523	active site
544404011524	I-site; other site
544404011525	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404011526	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
544404011527	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
544404011528	NADP binding site [chemical binding]; other site
544404011529	dimer interface [polypeptide binding]; other site
544404011530	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
544404011531	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
544404011532	carboxyltransferase (CT) interaction site; other site
544404011533	biotinylation site [posttranslational modification]; other site
544404011534	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
544404011535	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
544404011536	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
544404011537	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
544404011538	hypothetical protein; Provisional; Region: PRK10633
544404011539	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
544404011540	Na binding site [ion binding]; other site
544404011541	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
544404011542	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
544404011543	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
544404011544	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
544404011545	FMN binding site [chemical binding]; other site
544404011546	active site
544404011547	catalytic residues [active]
544404011548	substrate binding site [chemical binding]; other site
544404011549	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
544404011550	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
544404011551	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
544404011552	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404011553	DNA methylase; Region: N6_N4_Mtase; pfam01555
544404011554	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
544404011555	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
544404011556	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404011557	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
544404011558	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
544404011559	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404011560	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404011561	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
544404011562	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
544404011563	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404011564	substrate binding pocket [chemical binding]; other site
544404011565	membrane-bound complex binding site; other site
544404011566	hinge residues; other site
544404011567	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
544404011568	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404011569	conserved gate region; other site
544404011570	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404011571	dimer interface [polypeptide binding]; other site
544404011572	conserved gate region; other site
544404011573	putative PBP binding loops; other site
544404011574	ABC-ATPase subunit interface; other site
544404011575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404011576	dimer interface [polypeptide binding]; other site
544404011577	conserved gate region; other site
544404011578	putative PBP binding loops; other site
544404011579	ABC-ATPase subunit interface; other site
544404011580	Transposase; Region: HTH_Tnp_1; cl17663
544404011581	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404011582	putative transposase OrfB; Reviewed; Region: PHA02517
544404011583	HTH-like domain; Region: HTH_21; pfam13276
544404011584	Integrase core domain; Region: rve; pfam00665
544404011585	Integrase core domain; Region: rve_3; pfam13683
544404011586	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
544404011587	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
544404011588	Walker A/P-loop; other site
544404011589	ATP binding site [chemical binding]; other site
544404011590	Q-loop/lid; other site
544404011591	ABC transporter signature motif; other site
544404011592	Walker B; other site
544404011593	D-loop; other site
544404011594	H-loop/switch region; other site
544404011595	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
544404011596	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
544404011597	trimer interface [polypeptide binding]; other site
544404011598	putative metal binding site [ion binding]; other site
544404011599	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
544404011600	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
544404011601	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
544404011602	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
544404011603	shikimate binding site; other site
544404011604	NAD(P) binding site [chemical binding]; other site
544404011605	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
544404011606	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
544404011607	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
544404011608	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
544404011609	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
544404011610	hypothetical protein; Validated; Region: PRK03430
544404011611	hypothetical protein; Provisional; Region: PRK10736
544404011612	DNA protecting protein DprA; Region: dprA; TIGR00732
544404011613	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
544404011614	active site
544404011615	catalytic residues [active]
544404011616	metal binding site [ion binding]; metal-binding site
544404011617	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
544404011618	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
544404011619	putative active site [active]
544404011620	substrate binding site [chemical binding]; other site
544404011621	putative cosubstrate binding site; other site
544404011622	catalytic site [active]
544404011623	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
544404011624	substrate binding site [chemical binding]; other site
544404011625	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
544404011626	putative RNA binding site [nucleotide binding]; other site
544404011627	16S rRNA methyltransferase B; Provisional; Region: PRK10901
544404011628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404011629	S-adenosylmethionine binding site [chemical binding]; other site
544404011630	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
544404011631	TrkA-N domain; Region: TrkA_N; pfam02254
544404011632	TrkA-C domain; Region: TrkA_C; pfam02080
544404011633	TrkA-N domain; Region: TrkA_N; pfam02254
544404011634	TrkA-C domain; Region: TrkA_C; pfam02080
544404011635	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
544404011636	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
544404011637	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
544404011638	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
544404011639	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
544404011640	DNA binding residues [nucleotide binding]
544404011641	dimer interface [polypeptide binding]; other site
544404011642	metal binding site [ion binding]; metal-binding site
544404011643	hypothetical protein; Provisional; Region: PRK10203
544404011644	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
544404011645	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
544404011646	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
544404011647	alphaNTD homodimer interface [polypeptide binding]; other site
544404011648	alphaNTD - beta interaction site [polypeptide binding]; other site
544404011649	alphaNTD - beta' interaction site [polypeptide binding]; other site
544404011650	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
544404011651	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
544404011652	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
544404011653	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404011654	RNA binding surface [nucleotide binding]; other site
544404011655	30S ribosomal protein S11; Validated; Region: PRK05309
544404011656	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
544404011657	30S ribosomal protein S13; Region: bact_S13; TIGR03631
544404011658	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
544404011659	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
544404011660	SecY translocase; Region: SecY; pfam00344
544404011661	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
544404011662	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
544404011663	23S rRNA binding site [nucleotide binding]; other site
544404011664	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
544404011665	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
544404011666	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
544404011667	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
544404011668	23S rRNA interface [nucleotide binding]; other site
544404011669	5S rRNA interface [nucleotide binding]; other site
544404011670	L27 interface [polypeptide binding]; other site
544404011671	L5 interface [polypeptide binding]; other site
544404011672	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
544404011673	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
544404011674	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
544404011675	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
544404011676	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
544404011677	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
544404011678	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
544404011679	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
544404011680	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
544404011681	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
544404011682	RNA binding site [nucleotide binding]; other site
544404011683	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
544404011684	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
544404011685	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
544404011686	23S rRNA interface [nucleotide binding]; other site
544404011687	putative translocon interaction site; other site
544404011688	signal recognition particle (SRP54) interaction site; other site
544404011689	L23 interface [polypeptide binding]; other site
544404011690	trigger factor interaction site; other site
544404011691	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
544404011692	23S rRNA interface [nucleotide binding]; other site
544404011693	5S rRNA interface [nucleotide binding]; other site
544404011694	putative antibiotic binding site [chemical binding]; other site
544404011695	L25 interface [polypeptide binding]; other site
544404011696	L27 interface [polypeptide binding]; other site
544404011697	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
544404011698	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
544404011699	G-X-X-G motif; other site
544404011700	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
544404011701	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
544404011702	protein-rRNA interface [nucleotide binding]; other site
544404011703	putative translocon binding site; other site
544404011704	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
544404011705	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
544404011706	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
544404011707	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
544404011708	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
544404011709	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
544404011710	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
544404011711	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
544404011712	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
544404011713	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
544404011714	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
544404011715	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
544404011716	heme binding site [chemical binding]; other site
544404011717	ferroxidase pore; other site
544404011718	ferroxidase diiron center [ion binding]; other site
544404011719	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
544404011720	elongation factor Tu; Reviewed; Region: PRK00049
544404011721	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
544404011722	G1 box; other site
544404011723	GEF interaction site [polypeptide binding]; other site
544404011724	GTP/Mg2+ binding site [chemical binding]; other site
544404011725	Switch I region; other site
544404011726	G2 box; other site
544404011727	G3 box; other site
544404011728	Switch II region; other site
544404011729	G4 box; other site
544404011730	G5 box; other site
544404011731	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
544404011732	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
544404011733	Antibiotic Binding Site [chemical binding]; other site
544404011734	elongation factor G; Reviewed; Region: PRK00007
544404011735	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
544404011736	G1 box; other site
544404011737	putative GEF interaction site [polypeptide binding]; other site
544404011738	GTP/Mg2+ binding site [chemical binding]; other site
544404011739	Switch I region; other site
544404011740	G2 box; other site
544404011741	G3 box; other site
544404011742	Switch II region; other site
544404011743	G4 box; other site
544404011744	G5 box; other site
544404011745	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
544404011746	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
544404011747	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
544404011748	30S ribosomal protein S7; Validated; Region: PRK05302
544404011749	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
544404011750	S17 interaction site [polypeptide binding]; other site
544404011751	S8 interaction site; other site
544404011752	16S rRNA interaction site [nucleotide binding]; other site
544404011753	streptomycin interaction site [chemical binding]; other site
544404011754	23S rRNA interaction site [nucleotide binding]; other site
544404011755	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
544404011756	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
544404011757	sulfur relay protein TusC; Validated; Region: PRK00211
544404011758	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
544404011759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
544404011760	YheO-like PAS domain; Region: PAS_6; pfam08348
544404011761	HTH domain; Region: HTH_22; pfam13309
544404011762	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
544404011763	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
544404011764	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
544404011765	phi X174 lysis protein; Provisional; Region: PRK02793
544404011766	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
544404011767	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
544404011768	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
544404011769	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
544404011770	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
544404011771	TrkA-N domain; Region: TrkA_N; pfam02254
544404011772	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
544404011773	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
544404011774	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404011775	Walker A/P-loop; other site
544404011776	ATP binding site [chemical binding]; other site
544404011777	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
544404011778	ABC transporter signature motif; other site
544404011779	Walker B; other site
544404011780	D-loop; other site
544404011781	ABC transporter; Region: ABC_tran_2; pfam12848
544404011782	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
544404011783	putative hydrolase; Provisional; Region: PRK10985
544404011784	hypothetical protein; Provisional; Region: PRK04966
544404011785	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
544404011786	active site
544404011787	hypothetical protein; Provisional; Region: PRK10738
544404011788	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
544404011789	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
544404011790	ligand binding site [chemical binding]; other site
544404011791	flexible hinge region; other site
544404011792	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
544404011793	putative switch regulator; other site
544404011794	non-specific DNA interactions [nucleotide binding]; other site
544404011795	DNA binding site [nucleotide binding]
544404011796	sequence specific DNA binding site [nucleotide binding]; other site
544404011797	putative cAMP binding site [chemical binding]; other site
544404011798	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
544404011799	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
544404011800	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
544404011801	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
544404011802	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
544404011803	inhibitor-cofactor binding pocket; inhibition site
544404011804	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404011805	catalytic residue [active]
544404011806	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
544404011807	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
544404011808	glutamine binding [chemical binding]; other site
544404011809	catalytic triad [active]
544404011810	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
544404011811	cell filamentation protein Fic; Provisional; Region: PRK10347
544404011812	hypothetical protein; Provisional; Region: PRK10204
544404011813	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
544404011814	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
544404011815	substrate binding site [chemical binding]; other site
544404011816	putative transporter; Provisional; Region: PRK03699
544404011817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404011818	putative substrate translocation pore; other site
544404011819	nitrite reductase subunit NirD; Provisional; Region: PRK14989
544404011820	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404011821	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
544404011822	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
544404011823	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
544404011824	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
544404011825	nitrite transporter NirC; Provisional; Region: PRK11562
544404011826	siroheme synthase; Provisional; Region: cysG; PRK10637
544404011827	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
544404011828	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
544404011829	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
544404011830	active site
544404011831	SAM binding site [chemical binding]; other site
544404011832	homodimer interface [polypeptide binding]; other site
544404011833	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
544404011834	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
544404011835	hypothetical protein; Provisional; Region: PHA02764
544404011836	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
544404011837	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
544404011838	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
544404011839	dimer interface [polypeptide binding]; other site
544404011840	active site
544404011841	fructoselysine 3-epimerase; Provisional; Region: PRK09856
544404011842	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
544404011843	AP (apurinic/apyrimidinic) site pocket; other site
544404011844	DNA interaction; other site
544404011845	Metal-binding active site; metal-binding site
544404011846	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
544404011847	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404011848	DNA-binding site [nucleotide binding]; DNA binding site
544404011849	UTRA domain; Region: UTRA; pfam07702
544404011850	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
544404011851	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
544404011852	active site
544404011853	HIGH motif; other site
544404011854	dimer interface [polypeptide binding]; other site
544404011855	KMSKS motif; other site
544404011856	phosphoglycolate phosphatase; Provisional; Region: PRK13222
544404011857	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404011858	motif II; other site
544404011859	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
544404011860	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
544404011861	substrate binding site [chemical binding]; other site
544404011862	hexamer interface [polypeptide binding]; other site
544404011863	metal binding site [ion binding]; metal-binding site
544404011864	DNA adenine methylase; Provisional; Region: PRK10904
544404011865	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
544404011866	cell division protein DamX; Validated; Region: PRK10905
544404011867	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
544404011868	active site
544404011869	dimer interface [polypeptide binding]; other site
544404011870	metal binding site [ion binding]; metal-binding site
544404011871	shikimate kinase; Reviewed; Region: aroK; PRK00131
544404011872	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
544404011873	ADP binding site [chemical binding]; other site
544404011874	magnesium binding site [ion binding]; other site
544404011875	putative shikimate binding site; other site
544404011876	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
544404011877	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
544404011878	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
544404011879	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
544404011880	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
544404011881	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
544404011882	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
544404011883	Transglycosylase; Region: Transgly; pfam00912
544404011884	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
544404011885	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
544404011886	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
544404011887	ADP-ribose binding site [chemical binding]; other site
544404011888	dimer interface [polypeptide binding]; other site
544404011889	active site
544404011890	nudix motif; other site
544404011891	metal binding site [ion binding]; metal-binding site
544404011892	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
544404011893	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
544404011894	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404011895	motif II; other site
544404011896	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404011897	RNA binding surface [nucleotide binding]; other site
544404011898	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
544404011899	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
544404011900	dimerization interface [polypeptide binding]; other site
544404011901	domain crossover interface; other site
544404011902	redox-dependent activation switch; other site
544404011903	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
544404011904	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
544404011905	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
544404011906	active site
544404011907	substrate-binding site [chemical binding]; other site
544404011908	metal-binding site [ion binding]
544404011909	ATP binding site [chemical binding]; other site
544404011910	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
544404011911	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404011912	dimerization interface [polypeptide binding]; other site
544404011913	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404011914	dimer interface [polypeptide binding]; other site
544404011915	phosphorylation site [posttranslational modification]
544404011916	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404011917	ATP binding site [chemical binding]; other site
544404011918	G-X-G motif; other site
544404011919	osmolarity response regulator; Provisional; Region: ompR; PRK09468
544404011920	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404011921	active site
544404011922	phosphorylation site [posttranslational modification]
544404011923	intermolecular recognition site; other site
544404011924	dimerization interface [polypeptide binding]; other site
544404011925	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404011926	DNA binding site [nucleotide binding]
544404011927	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
544404011928	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
544404011929	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
544404011930	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
544404011931	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
544404011932	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
544404011933	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
544404011934	RNA binding site [nucleotide binding]; other site
544404011935	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
544404011936	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
544404011937	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
544404011938	G1 box; other site
544404011939	GTP/Mg2+ binding site [chemical binding]; other site
544404011940	Switch I region; other site
544404011941	G2 box; other site
544404011942	G3 box; other site
544404011943	Switch II region; other site
544404011944	G4 box; other site
544404011945	G5 box; other site
544404011946	Nucleoside recognition; Region: Gate; pfam07670
544404011947	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
544404011948	Nucleoside recognition; Region: Gate; pfam07670
544404011949	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
544404011950	putative transposase; Provisional; Region: PRK09857
544404011951	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
544404011952	carboxylesterase BioH; Provisional; Region: PRK10349
544404011953	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
544404011954	DNA utilization protein GntX; Provisional; Region: PRK11595
544404011955	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404011956	active site
544404011957	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
544404011958	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
544404011959	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
544404011960	high-affinity gluconate transporter; Provisional; Region: PRK14984
544404011961	gluconate transporter; Region: gntP; TIGR00791
544404011962	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
544404011963	4-alpha-glucanotransferase; Region: malQ; TIGR00217
544404011964	maltodextrin phosphorylase; Provisional; Region: PRK14985
544404011965	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
544404011966	homodimer interface [polypeptide binding]; other site
544404011967	active site pocket [active]
544404011968	transcriptional regulator MalT; Provisional; Region: PRK04841
544404011969	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404011970	DNA binding residues [nucleotide binding]
544404011971	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
544404011972	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
544404011973	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
544404011974	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
544404011975	putative active site [active]
544404011976	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
544404011977	hypothetical protein; Reviewed; Region: PRK09588
544404011978	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
544404011979	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
544404011980	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404011981	Walker A motif; other site
544404011982	ATP binding site [chemical binding]; other site
544404011983	Walker B motif; other site
544404011984	arginine finger; other site
544404011985	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
544404011986	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
544404011987	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404011988	intramembrane serine protease GlpG; Provisional; Region: PRK10907
544404011989	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
544404011990	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
544404011991	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
544404011992	active site residue [active]
544404011993	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
544404011994	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
544404011995	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
544404011996	glycogen phosphorylase; Provisional; Region: PRK14986
544404011997	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
544404011998	homodimer interface [polypeptide binding]; other site
544404011999	active site pocket [active]
544404012000	glycogen synthase; Provisional; Region: glgA; PRK00654
544404012001	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
544404012002	ADP-binding pocket [chemical binding]; other site
544404012003	homodimer interface [polypeptide binding]; other site
544404012004	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
544404012005	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
544404012006	ligand binding site; other site
544404012007	oligomer interface; other site
544404012008	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
544404012009	sulfate 1 binding site; other site
544404012010	glycogen debranching enzyme; Provisional; Region: PRK03705
544404012011	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
544404012012	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
544404012013	active site
544404012014	catalytic site [active]
544404012015	glycogen branching enzyme; Provisional; Region: PRK05402
544404012016	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
544404012017	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
544404012018	active site
544404012019	catalytic site [active]
544404012020	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
544404012021	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
544404012022	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
544404012023	putative antibiotic transporter; Provisional; Region: PRK10739
544404012024	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
544404012025	DNA protecting protein DprA; Region: dprA; TIGR00732
544404012026	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
544404012027	non-specific DNA interactions [nucleotide binding]; other site
544404012028	DNA binding site [nucleotide binding]
544404012029	sequence specific DNA binding site [nucleotide binding]; other site
544404012030	putative cAMP binding site [chemical binding]; other site
544404012031	low affinity gluconate transporter; Provisional; Region: PRK10472
544404012032	gluconate transporter; Region: gntP; TIGR00791
544404012033	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
544404012034	ATP-binding site [chemical binding]; other site
544404012035	Gluconate-6-phosphate binding site [chemical binding]; other site
544404012036	Shikimate kinase; Region: SKI; pfam01202
544404012037	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
544404012038	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404012039	DNA binding site [nucleotide binding]
544404012040	domain linker motif; other site
544404012041	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
544404012042	putative ligand binding site [chemical binding]; other site
544404012043	putative dimerization interface [polypeptide binding]; other site
544404012044	Pirin-related protein [General function prediction only]; Region: COG1741
544404012045	Pirin; Region: Pirin; pfam02678
544404012046	putative oxidoreductase; Provisional; Region: PRK10206
544404012047	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
544404012048	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
544404012049	putative acetyltransferase YhhY; Provisional; Region: PRK10140
544404012050	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404012051	Coenzyme A binding pocket [chemical binding]; other site
544404012052	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
544404012053	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
544404012054	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
544404012055	hypothetical protein; Provisional; Region: PRK10350
544404012056	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
544404012057	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
544404012058	putative active site [active]
544404012059	catalytic site [active]
544404012060	putative metal binding site [ion binding]; other site
544404012061	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
544404012062	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
544404012063	Walker A/P-loop; other site
544404012064	ATP binding site [chemical binding]; other site
544404012065	Q-loop/lid; other site
544404012066	ABC transporter signature motif; other site
544404012067	Walker B; other site
544404012068	D-loop; other site
544404012069	H-loop/switch region; other site
544404012070	TOBE domain; Region: TOBE_2; pfam08402
544404012071	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
544404012072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404012073	dimer interface [polypeptide binding]; other site
544404012074	conserved gate region; other site
544404012075	putative PBP binding loops; other site
544404012076	ABC-ATPase subunit interface; other site
544404012077	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
544404012078	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404012079	dimer interface [polypeptide binding]; other site
544404012080	conserved gate region; other site
544404012081	putative PBP binding loops; other site
544404012082	ABC-ATPase subunit interface; other site
544404012083	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
544404012084	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
544404012085	Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats [Function unknown]; Region: COG4700
544404012086	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
544404012087	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
544404012088	binding surface
544404012089	TPR motif; other site
544404012090	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
544404012091	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
544404012092	Walker A/P-loop; other site
544404012093	ATP binding site [chemical binding]; other site
544404012094	Q-loop/lid; other site
544404012095	ABC transporter signature motif; other site
544404012096	Walker B; other site
544404012097	D-loop; other site
544404012098	H-loop/switch region; other site
544404012099	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
544404012100	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
544404012101	Walker A/P-loop; other site
544404012102	ATP binding site [chemical binding]; other site
544404012103	Q-loop/lid; other site
544404012104	ABC transporter signature motif; other site
544404012105	Walker B; other site
544404012106	D-loop; other site
544404012107	H-loop/switch region; other site
544404012108	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
544404012109	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
544404012110	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
544404012111	TM-ABC transporter signature motif; other site
544404012112	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404012113	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
544404012114	TM-ABC transporter signature motif; other site
544404012115	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
544404012116	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
544404012117	dimerization interface [polypeptide binding]; other site
544404012118	ligand binding site [chemical binding]; other site
544404012119	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
544404012120	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
544404012121	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
544404012122	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
544404012123	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
544404012124	dimerization interface [polypeptide binding]; other site
544404012125	ligand binding site [chemical binding]; other site
544404012126	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
544404012127	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
544404012128	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
544404012129	DNA binding residues [nucleotide binding]
544404012130	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
544404012131	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
544404012132	cell division protein FtsE; Provisional; Region: PRK10908
544404012133	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404012134	Walker A/P-loop; other site
544404012135	ATP binding site [chemical binding]; other site
544404012136	Q-loop/lid; other site
544404012137	ABC transporter signature motif; other site
544404012138	Walker B; other site
544404012139	D-loop; other site
544404012140	H-loop/switch region; other site
544404012141	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
544404012142	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
544404012143	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
544404012144	P loop; other site
544404012145	GTP binding site [chemical binding]; other site
544404012146	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
544404012147	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404012148	S-adenosylmethionine binding site [chemical binding]; other site
544404012149	hypothetical protein; Provisional; Region: PRK10910
544404012150	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
544404012151	Predicted membrane protein [Function unknown]; Region: COG3714
544404012152	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
544404012153	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
544404012154	metal-binding site [ion binding]
544404012155	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
544404012156	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
544404012157	CPxP  motif; other site
544404012158	hypothetical protein; Provisional; Region: PRK11212
544404012159	hypothetical protein; Provisional; Region: PRK11615
544404012160	major facilitator superfamily transporter; Provisional; Region: PRK05122
544404012161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012162	putative substrate translocation pore; other site
544404012163	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
544404012164	Domain of unknown function DUF20; Region: UPF0118; pfam01594
544404012165	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
544404012166	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404012167	S-adenosylmethionine binding site [chemical binding]; other site
544404012168	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
544404012169	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
544404012170	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
544404012171	putative acyl-acceptor binding pocket; other site
544404012172	Phosphopantetheine attachment site; Region: PP-binding; cl09936
544404012173	acyl carrier protein; Provisional; Region: PRK05350
544404012174	Predicted membrane protein [Function unknown]; Region: COG4648
544404012175	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases [Lipid metabolism]; Region: FabA; COG0764
544404012176	active site 2 [active]
544404012177	active site 1 [active]
544404012178	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
544404012179	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
544404012180	Ligand binding site; other site
544404012181	Putative Catalytic site; other site
544404012182	DXD motif; other site
544404012183	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
544404012184	putative acyl-acceptor binding pocket; other site
544404012185	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
544404012186	active site
544404012187	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
544404012188	Predicted exporter [General function prediction only]; Region: COG4258
544404012189	Protein of unknown function (DUF3261); Region: DUF3261; pfam11659
544404012190	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
544404012191	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
544404012192	dimer interface [polypeptide binding]; other site
544404012193	active site
544404012194	Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289
544404012195	putative active site 1 [active]
544404012196	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
544404012197	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
544404012198	NAD(P) binding site [chemical binding]; other site
544404012199	active site
544404012200	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
544404012201	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
544404012202	dimer interface [polypeptide binding]; other site
544404012203	active site
544404012204	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
544404012205	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
544404012206	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
544404012207	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
544404012208	substrate binding site [chemical binding]; other site
544404012209	nickel transporter permease NikB; Provisional; Region: PRK10352
544404012210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404012211	dimer interface [polypeptide binding]; other site
544404012212	conserved gate region; other site
544404012213	putative PBP binding loops; other site
544404012214	ABC-ATPase subunit interface; other site
544404012215	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
544404012216	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404012217	dimer interface [polypeptide binding]; other site
544404012218	conserved gate region; other site
544404012219	putative PBP binding loops; other site
544404012220	ABC-ATPase subunit interface; other site
544404012221	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
544404012222	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404012223	Walker A/P-loop; other site
544404012224	ATP binding site [chemical binding]; other site
544404012225	Q-loop/lid; other site
544404012226	ABC transporter signature motif; other site
544404012227	Walker B; other site
544404012228	D-loop; other site
544404012229	H-loop/switch region; other site
544404012230	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
544404012231	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
544404012232	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404012233	Walker A/P-loop; other site
544404012234	ATP binding site [chemical binding]; other site
544404012235	Q-loop/lid; other site
544404012236	ABC transporter signature motif; other site
544404012237	Walker B; other site
544404012238	D-loop; other site
544404012239	H-loop/switch region; other site
544404012240	nickel responsive regulator; Provisional; Region: PRK02967
544404012241	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
544404012242	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
544404012243	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404012244	DNA-binding site [nucleotide binding]; DNA binding site
544404012245	UTRA domain; Region: UTRA; pfam07702
544404012246	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404012247	active site
544404012248	phosphorylation site [posttranslational modification]
544404012249	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
544404012250	active site
544404012251	P-loop; other site
544404012252	phosphorylation site [posttranslational modification]
544404012253	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
544404012254	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
544404012255	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
544404012256	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
544404012257	putative N- and C-terminal domain interface [polypeptide binding]; other site
544404012258	putative active site [active]
544404012259	putative MgATP binding site [chemical binding]; other site
544404012260	catalytic site [active]
544404012261	metal binding site [ion binding]; metal-binding site
544404012262	putative carbohydrate binding site [chemical binding]; other site
544404012263	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
544404012264	dimerization domain swap beta strand [polypeptide binding]; other site
544404012265	regulatory protein interface [polypeptide binding]; other site
544404012266	active site
544404012267	regulatory phosphorylation site [posttranslational modification]; other site
544404012268	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
544404012269	intersubunit interface [polypeptide binding]; other site
544404012270	active site
544404012271	zinc binding site [ion binding]; other site
544404012272	Na+ binding site [ion binding]; other site
544404012273	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
544404012274	HicB family; Region: HicB; pfam05534
544404012275	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
544404012276	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
544404012277	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
544404012278	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
544404012279	Walker A/P-loop; other site
544404012280	ATP binding site [chemical binding]; other site
544404012281	Q-loop/lid; other site
544404012282	ABC transporter signature motif; other site
544404012283	Walker B; other site
544404012284	D-loop; other site
544404012285	H-loop/switch region; other site
544404012286	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
544404012287	Walker A/P-loop; other site
544404012288	ATP binding site [chemical binding]; other site
544404012289	Q-loop/lid; other site
544404012290	ABC transporter signature motif; other site
544404012291	Walker B; other site
544404012292	D-loop; other site
544404012293	H-loop/switch region; other site
544404012294	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
544404012295	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
544404012296	HlyD family secretion protein; Region: HlyD; pfam00529
544404012297	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404012298	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404012299	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
544404012300	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
544404012301	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
544404012302	Predicted flavoproteins [General function prediction only]; Region: COG2081
544404012303	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404012304	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
544404012305	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
544404012306	universal stress protein UspB; Provisional; Region: PRK04960
544404012307	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404012308	Ligand Binding Site [chemical binding]; other site
544404012309	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
544404012310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012311	POT family; Region: PTR2; pfam00854
544404012312	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404012313	S-adenosylmethionine binding site [chemical binding]; other site
544404012314	oligopeptidase A; Provisional; Region: PRK10911
544404012315	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
544404012316	active site
544404012317	Zn binding site [ion binding]; other site
544404012318	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
544404012319	glutathione reductase; Validated; Region: PRK06116
544404012320	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
544404012321	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404012322	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
544404012323	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404012324	dimerization interface [polypeptide binding]; other site
544404012325	putative DNA binding site [nucleotide binding]; other site
544404012326	putative Zn2+ binding site [ion binding]; other site
544404012327	arsenical pump membrane protein; Provisional; Region: PRK15445
544404012328	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
544404012329	transmembrane helices; other site
544404012330	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
544404012331	ArsC family; Region: ArsC; pfam03960
544404012332	catalytic residues [active]
544404012333	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
544404012334	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404012335	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404012336	DNA binding residues [nucleotide binding]
544404012337	dimerization interface [polypeptide binding]; other site
544404012338	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
544404012339	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
544404012340	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
544404012341	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
544404012342	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404012343	N-terminal plug; other site
544404012344	ligand-binding site [chemical binding]; other site
544404012345	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
544404012346	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
544404012347	putative hemin binding site; other site
544404012348	coproporphyrinogen III oxidase; Provisional; Region: PRK09058
544404012349	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404012350	FeS/SAM binding site; other site
544404012351	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugX; COG3721
544404012352	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
544404012353	NADH(P)-binding; Region: NAD_binding_10; pfam13460
544404012354	NAD(P) binding site [chemical binding]; other site
544404012355	putative active site [active]
544404012356	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
544404012357	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
544404012358	ABC-ATPase subunit  interface; other site
544404012359	dimer interface [polypeptide binding]; other site
544404012360	putative PBP binding regions; other site
544404012361	ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG4559
544404012362	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
544404012363	Walker A/P-loop; other site
544404012364	ATP binding site [chemical binding]; other site
544404012365	Q-loop/lid; other site
544404012366	ABC transporter signature motif; other site
544404012367	Walker B; other site
544404012368	D-loop; other site
544404012369	H-loop/switch region; other site
544404012370	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
544404012371	MgtC family; Region: MgtC; pfam02308
544404012372	acid-resistance protein; Provisional; Region: hdeB; PRK11566
544404012373	acid-resistance protein; Provisional; Region: PRK10208
544404012374	acid-resistance membrane protein; Provisional; Region: PRK10209
544404012375	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
544404012376	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
544404012377	pyruvate kinase; Provisional; Region: PRK05826
544404012378	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
544404012379	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404012380	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404012381	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
544404012382	Protein export membrane protein; Region: SecD_SecF; cl14618
544404012383	transcriptional regulator YdeO; Provisional; Region: PRK09940
544404012384	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404012385	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
544404012386	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404012387	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
544404012388	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404012389	catalytic residue [active]
544404012390	Haem-binding domain; Region: Haem_bd; pfam14376
544404012391	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
544404012392	trehalase; Provisional; Region: treF; PRK13270
544404012393	Trehalase; Region: Trehalase; pfam01204
544404012394	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404012395	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404012396	DNA binding residues [nucleotide binding]
544404012397	dimerization interface [polypeptide binding]; other site
544404012398	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404012399	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404012400	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
544404012401	putative effector binding pocket; other site
544404012402	putative dimerization interface [polypeptide binding]; other site
544404012403	inner membrane protein YhjD; Region: TIGR00766
544404012404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012405	metabolite-proton symporter; Region: 2A0106; TIGR00883
544404012406	putative substrate translocation pore; other site
544404012407	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
544404012408	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
544404012409	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404012410	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404012411	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
544404012412	substrate binding site [chemical binding]; other site
544404012413	ATP binding site [chemical binding]; other site
544404012414	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
544404012415	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
544404012416	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
544404012417	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
544404012418	putative diguanylate cyclase; Provisional; Region: PRK13561
544404012419	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
544404012420	metal binding site [ion binding]; metal-binding site
544404012421	active site
544404012422	I-site; other site
544404012423	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404012424	TPR repeat; Region: TPR_11; pfam13414
544404012425	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404012426	binding surface
544404012427	TPR motif; other site
544404012428	Tetratricopeptide repeat; Region: TPR_16; pfam13432
544404012429	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404012430	binding surface
544404012431	TPR repeat; Region: TPR_11; pfam13414
544404012432	TPR motif; other site
544404012433	Tetratricopeptide repeat; Region: TPR_16; pfam13432
544404012434	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
544404012435	endo-1,4-D-glucanase; Provisional; Region: PRK11097
544404012436	cellulose synthase regulator protein; Provisional; Region: PRK11114
544404012437	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
544404012438	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
544404012439	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
544404012440	DXD motif; other site
544404012441	PilZ domain; Region: PilZ; pfam07238
544404012442	cell division protein; Provisional; Region: PRK10037
544404012443	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
544404012444	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
544404012445	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
544404012446	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
544404012447	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
544404012448	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
544404012449	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
544404012450	serine transporter; Region: stp; TIGR00814
544404012451	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
544404012452	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404012453	Walker A/P-loop; other site
544404012454	ATP binding site [chemical binding]; other site
544404012455	Q-loop/lid; other site
544404012456	ABC transporter signature motif; other site
544404012457	Walker B; other site
544404012458	D-loop; other site
544404012459	H-loop/switch region; other site
544404012460	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
544404012461	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
544404012462	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404012463	Walker A/P-loop; other site
544404012464	ATP binding site [chemical binding]; other site
544404012465	Q-loop/lid; other site
544404012466	ABC transporter signature motif; other site
544404012467	Walker B; other site
544404012468	D-loop; other site
544404012469	H-loop/switch region; other site
544404012470	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
544404012471	dipeptide transporter; Provisional; Region: PRK10913
544404012472	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
544404012473	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404012474	dimer interface [polypeptide binding]; other site
544404012475	conserved gate region; other site
544404012476	putative PBP binding loops; other site
544404012477	ABC-ATPase subunit interface; other site
544404012478	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
544404012479	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404012480	dimer interface [polypeptide binding]; other site
544404012481	conserved gate region; other site
544404012482	putative PBP binding loops; other site
544404012483	ABC-ATPase subunit interface; other site
544404012484	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
544404012485	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
544404012486	peptide binding site [polypeptide binding]; other site
544404012487	phosphoethanolamine transferase; Provisional; Region: PRK11560
544404012488	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
544404012489	Sulfatase; Region: Sulfatase; pfam00884
544404012490	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
544404012491	Fimbrial protein; Region: Fimbrial; cl01416
544404012492	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
544404012493	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404012494	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404012495	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
544404012496	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
544404012497	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012498	putative substrate translocation pore; other site
544404012499	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
544404012500	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
544404012501	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
544404012502	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404012503	Coenzyme A binding pocket [chemical binding]; other site
544404012504	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
544404012505	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
544404012506	molybdopterin cofactor binding site [chemical binding]; other site
544404012507	substrate binding site [chemical binding]; other site
544404012508	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
544404012509	molybdopterin cofactor binding site; other site
544404012510	putative outer membrane lipoprotein; Provisional; Region: PRK10510
544404012511	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404012512	ligand binding site [chemical binding]; other site
544404012513	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
544404012514	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
544404012515	dimerization interface [polypeptide binding]; other site
544404012516	ligand binding site [chemical binding]; other site
544404012517	NADP binding site [chemical binding]; other site
544404012518	catalytic site [active]
544404012519	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
544404012520	Predicted transcriptional regulator [Transcription]; Region: COG2944
544404012521	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404012522	non-specific DNA binding site [nucleotide binding]; other site
544404012523	salt bridge; other site
544404012524	sequence-specific DNA binding site [nucleotide binding]; other site
544404012525	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
544404012526	DNA-binding site [nucleotide binding]; DNA binding site
544404012527	RNA-binding motif; other site
544404012528	small toxic polypeptide; Provisional; Region: PRK09759
544404012529	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
544404012530	DALR anticodon binding domain; Region: DALR_1; pfam05746
544404012531	anticodon binding site; other site
544404012532	tRNA binding surface [nucleotide binding]; other site
544404012533	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
544404012534	dimer interface [polypeptide binding]; other site
544404012535	motif 1; other site
544404012536	active site
544404012537	motif 2; other site
544404012538	motif 3; other site
544404012539	YsaB-like lipoprotein; Region: YsaB; pfam13983
544404012540	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
544404012541	Acyltransferase family; Region: Acyl_transf_3; pfam01757
544404012542	hypothetical protein; Provisional; Region: PRK11383
544404012543	yiaA/B two helix domain; Region: YiaAB; pfam05360
544404012544	yiaA/B two helix domain; Region: YiaAB; pfam05360
544404012545	hypothetical protein; Provisional; Region: PRK11403
544404012546	yiaA/B two helix domain; Region: YiaAB; pfam05360
544404012547	xylulokinase; Provisional; Region: PRK15027
544404012548	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
544404012549	N- and C-terminal domain interface [polypeptide binding]; other site
544404012550	active site
544404012551	MgATP binding site [chemical binding]; other site
544404012552	catalytic site [active]
544404012553	metal binding site [ion binding]; metal-binding site
544404012554	xylulose binding site [chemical binding]; other site
544404012555	homodimer interface [polypeptide binding]; other site
544404012556	xylose isomerase; Provisional; Region: PRK05474
544404012557	xylose isomerase; Region: xylose_isom_A; TIGR02630
544404012558	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
544404012559	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
544404012560	putative ligand binding site [chemical binding]; other site
544404012561	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
544404012562	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404012563	Walker A/P-loop; other site
544404012564	ATP binding site [chemical binding]; other site
544404012565	Q-loop/lid; other site
544404012566	ABC transporter signature motif; other site
544404012567	Walker B; other site
544404012568	D-loop; other site
544404012569	H-loop/switch region; other site
544404012570	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404012571	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404012572	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404012573	TM-ABC transporter signature motif; other site
544404012574	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
544404012575	putative dimerization interface [polypeptide binding]; other site
544404012576	Transcriptional regulators [Transcription]; Region: PurR; COG1609
544404012577	putative ligand binding site [chemical binding]; other site
544404012578	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404012579	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404012580	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404012581	hypothetical protein; Provisional; Region: PRK10356
544404012582	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
544404012583	alpha-amylase; Reviewed; Region: malS; PRK09505
544404012584	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
544404012585	active site
544404012586	catalytic site [active]
544404012587	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
544404012588	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404012589	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404012590	homodimer interface [polypeptide binding]; other site
544404012591	catalytic residue [active]
544404012592	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
544404012593	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
544404012594	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
544404012595	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
544404012596	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404012597	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
544404012598	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
544404012599	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
544404012600	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
544404012601	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
544404012602	Transcriptional regulator [Transcription]; Region: LysR; COG0583
544404012603	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404012604	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
544404012605	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
544404012606	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404012607	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404012608	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
544404012609	FlxA-like protein; Region: FlxA; pfam14282
544404012610	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
544404012611	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
544404012612	NAD(P) binding site [chemical binding]; other site
544404012613	catalytic residues [active]
544404012614	Fic family protein [Function unknown]; Region: COG3177
544404012615	Fic/DOC family; Region: Fic; pfam02661
544404012616	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
544404012617	putative alcohol dehydrogenase; Provisional; Region: PRK09860
544404012618	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
544404012619	dimer interface [polypeptide binding]; other site
544404012620	active site
544404012621	metal binding site [ion binding]; metal-binding site
544404012622	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
544404012623	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
544404012624	G1 box; other site
544404012625	putative GEF interaction site [polypeptide binding]; other site
544404012626	GTP/Mg2+ binding site [chemical binding]; other site
544404012627	Switch I region; other site
544404012628	G2 box; other site
544404012629	G3 box; other site
544404012630	Switch II region; other site
544404012631	G4 box; other site
544404012632	G5 box; other site
544404012633	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
544404012634	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
544404012635	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
544404012636	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
544404012637	selenocysteine synthase; Provisional; Region: PRK04311
544404012638	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
544404012639	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
544404012640	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
544404012641	catalytic residue [active]
544404012642	putative glutathione S-transferase; Provisional; Region: PRK10357
544404012643	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
544404012644	putative C-terminal domain interface [polypeptide binding]; other site
544404012645	putative GSH binding site (G-site) [chemical binding]; other site
544404012646	putative dimer interface [polypeptide binding]; other site
544404012647	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
544404012648	dimer interface [polypeptide binding]; other site
544404012649	N-terminal domain interface [polypeptide binding]; other site
544404012650	putative substrate binding pocket (H-site) [chemical binding]; other site
544404012651	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404012652	RHS protein; Region: RHS; pfam03527
544404012653	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404012654	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
544404012655	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
544404012656	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404012657	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404012658	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
544404012659	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
544404012660	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
544404012661	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
544404012662	active site
544404012663	P-loop; other site
544404012664	phosphorylation site [posttranslational modification]
544404012665	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404012666	active site
544404012667	phosphorylation site [posttranslational modification]
544404012668	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
544404012669	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
544404012670	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
544404012671	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
544404012672	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
544404012673	hypothetical protein; Provisional; Region: PRK11020
544404012674	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
544404012675	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
544404012676	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
544404012677	trimer interface [polypeptide binding]; other site
544404012678	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
544404012679	trimer interface [polypeptide binding]; other site
544404012680	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
544404012681	trimer interface [polypeptide binding]; other site
544404012682	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
544404012683	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
544404012684	trimer interface [polypeptide binding]; other site
544404012685	Haemagglutinin; Region: HIM; pfam05662
544404012686	Haemagglutinin; Region: HIM; pfam05662
544404012687	YadA-like C-terminal region; Region: YadA; pfam03895
544404012688	L-lactate permease; Provisional; Region: PRK10420
544404012689	glycolate transporter; Provisional; Region: PRK09695
544404012690	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
544404012691	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404012692	DNA-binding site [nucleotide binding]; DNA binding site
544404012693	FCD domain; Region: FCD; pfam07729
544404012694	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
544404012695	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
544404012696	phosphate binding site [ion binding]; other site
544404012697	putative rRNA methylase; Provisional; Region: PRK10358
544404012698	serine acetyltransferase; Provisional; Region: cysE; PRK11132
544404012699	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
544404012700	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
544404012701	trimer interface [polypeptide binding]; other site
544404012702	active site
544404012703	substrate binding site [chemical binding]; other site
544404012704	CoA binding site [chemical binding]; other site
544404012705	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
544404012706	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
544404012707	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
544404012708	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
544404012709	SecA binding site; other site
544404012710	Preprotein binding site; other site
544404012711	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
544404012712	GSH binding site [chemical binding]; other site
544404012713	catalytic residues [active]
544404012714	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
544404012715	active site residue [active]
544404012716	phosphoglyceromutase; Provisional; Region: PRK05434
544404012717	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
544404012718	AmiB activator; Provisional; Region: PRK11637
544404012719	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
544404012720	Peptidase family M23; Region: Peptidase_M23; pfam01551
544404012721	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
544404012722	NodB motif; other site
544404012723	putative active site [active]
544404012724	putative catalytic site [active]
544404012725	Zn binding site [ion binding]; other site
544404012726	putative glycosyl transferase; Provisional; Region: PRK10073
544404012727	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
544404012728	active site
544404012729	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
544404012730	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
544404012731	NAD(P) binding site [chemical binding]; other site
544404012732	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
544404012733	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
544404012734	substrate-cofactor binding pocket; other site
544404012735	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404012736	catalytic residue [active]
544404012737	hypothetical protein; Provisional; Region: PRK11346
544404012738	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
544404012739	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
544404012740	NADP binding site [chemical binding]; other site
544404012741	homopentamer interface [polypeptide binding]; other site
544404012742	substrate binding site [chemical binding]; other site
544404012743	active site
544404012744	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
544404012745	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
544404012746	putative active site [active]
544404012747	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
544404012748	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
544404012749	putative active site [active]
544404012750	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
544404012751	O-antigen ligase RfaL; Provisional; Region: PRK15487
544404012752	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
544404012753	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
544404012754	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
544404012755	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
544404012756	Ligand binding site; other site
544404012757	metal-binding site
544404012758	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
544404012759	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
544404012760	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
544404012761	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
544404012762	Ligand binding site; other site
544404012763	metal-binding site
544404012764	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
544404012765	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
544404012766	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
544404012767	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
544404012768	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
544404012769	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
544404012770	putative active site [active]
544404012771	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
544404012772	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
544404012773	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
544404012774	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
544404012775	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
544404012776	active site
544404012777	(T/H)XGH motif; other site
544404012778	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
544404012779	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
544404012780	DNA binding site [nucleotide binding]
544404012781	catalytic residue [active]
544404012782	H2TH interface [polypeptide binding]; other site
544404012783	putative catalytic residues [active]
544404012784	turnover-facilitating residue; other site
544404012785	intercalation triad [nucleotide binding]; other site
544404012786	8OG recognition residue [nucleotide binding]; other site
544404012787	putative reading head residues; other site
544404012788	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
544404012789	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
544404012790	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
544404012791	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
544404012792	hypothetical protein; Reviewed; Region: PRK00024
544404012793	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
544404012794	MPN+ (JAMM) motif; other site
544404012795	Zinc-binding site [ion binding]; other site
544404012796	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
544404012797	Flavoprotein; Region: Flavoprotein; pfam02441
544404012798	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
544404012799	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
544404012800	trimer interface [polypeptide binding]; other site
544404012801	active site
544404012802	division inhibitor protein; Provisional; Region: slmA; PRK09480
544404012803	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404012804	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
544404012805	active site
544404012806	ribonuclease PH; Reviewed; Region: rph; PRK00173
544404012807	Ribonuclease PH; Region: RNase_PH_bact; cd11362
544404012808	hexamer interface [polypeptide binding]; other site
544404012809	active site
544404012810	hypothetical protein; Provisional; Region: PRK11820
544404012811	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
544404012812	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
544404012813	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
544404012814	BRO family, N-terminal domain; Region: Bro-N; pfam02498
544404012815	Predicted membrane protein [Function unknown]; Region: COG2860
544404012816	UPF0126 domain; Region: UPF0126; pfam03458
544404012817	UPF0126 domain; Region: UPF0126; pfam03458
544404012818	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
544404012819	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
544404012820	nucleotide binding pocket [chemical binding]; other site
544404012821	K-X-D-G motif; other site
544404012822	catalytic site [active]
544404012823	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
544404012824	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
544404012825	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
544404012826	catalytic site [active]
544404012827	G-X2-G-X-G-K; other site
544404012828	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
544404012829	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
544404012830	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
544404012831	Zn2+ binding site [ion binding]; other site
544404012832	Mg2+ binding site [ion binding]; other site
544404012833	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
544404012834	synthetase active site [active]
544404012835	NTP binding site [chemical binding]; other site
544404012836	metal binding site [ion binding]; metal-binding site
544404012837	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
544404012838	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
544404012839	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
544404012840	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
544404012841	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
544404012842	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
544404012843	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
544404012844	generic binding surface II; other site
544404012845	ssDNA binding site; other site
544404012846	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404012847	ATP binding site [chemical binding]; other site
544404012848	putative Mg++ binding site [ion binding]; other site
544404012849	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404012850	nucleotide binding region [chemical binding]; other site
544404012851	ATP-binding site [chemical binding]; other site
544404012852	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
544404012853	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
544404012854	AsmA family; Region: AsmA; pfam05170
544404012855	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
544404012856	putative alpha-glucosidase; Provisional; Region: PRK10658
544404012857	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
544404012858	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
544404012859	active site
544404012860	homotrimer interface [polypeptide binding]; other site
544404012861	catalytic site [active]
544404012862	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
544404012863	putative transporter; Provisional; Region: PRK11462
544404012864	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
544404012865	integrase; Provisional; Region: PRK09692
544404012866	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404012867	active site
544404012868	Int/Topo IB signature motif; other site
544404012869	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404012870	Transposase; Region: HTH_Tnp_1; cl17663
544404012871	Integrase core domain; Region: rve; pfam00665
544404012872	DDE domain; Region: DDE_Tnp_IS240; pfam13610
544404012873	Integrase core domain; Region: rve_3; pfam13683
544404012874	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
544404012875	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
544404012876	Transposase; Region: HTH_Tnp_1; pfam01527
544404012877	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404012878	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404012879	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404012880	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404012881	homodimer interface [polypeptide binding]; other site
544404012882	putative GKAP docking site [polypeptide binding]; other site
544404012883	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404012884	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404012885	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404012886	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404012887	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404012888	type III secretion system protein, SsaH family; Region: type_III_ssaH; TIGR02498
544404012889	type III secretion apparatus needle protein; Region: III_needle; TIGR02105
544404012890	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
544404012891	Enterobacterial EspB protein; Region: EspB; pfam05802
544404012892	Uncharacterized conserved protein [Function unknown]; Region: COG5613
544404012893	EspA-like secreted protein; Region: EspA; pfam03433
544404012894	HrpJ-like domain; Region: HrpJ; pfam07201
544404012895	type III secretion effector delivery regulator, TyeA family; Region: type_III_tyeA; TIGR02511
544404012896	type III secretion system protein SsaD; Provisional; Region: PRK15367
544404012897	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
544404012898	LysM domain; Region: LysM; pfam01476
544404012899	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
544404012900	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
544404012901	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404012902	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
544404012903	Intimin C-type lectin domain; Region: Intimin_C; pfam07979
544404012904	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
544404012905	Translocated intimin receptor (Tir) N-terminus; Region: Tir_receptor_N; pfam07490
544404012906	Translocated intimin receptor (Tir) intimin-binding domain; Region: Tir_receptor_M; pfam03549
544404012907	Translocated intimin receptor (Tir) C-terminus; Region: Tir_receptor_C; pfam07489
544404012908	IpaB/EvcA family; Region: IpaB_EvcA; pfam03278
544404012909	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
544404012910	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
544404012911	Protein of unknown function (DUF1106); Region: DUF1106; pfam06523
544404012912	type III secretion apparatus H+-transporting two-sector ATPase; Region: III_secr_ATP; TIGR02546
544404012913	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
544404012914	Walker A motif/ATP binding site; other site
544404012915	Walker B motif; other site
544404012916	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
544404012917	FHIPEP family; Region: FHIPEP; pfam00771
544404012918	SepZ; Region: SepZ; pfam06066
544404012919	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
544404012920	outer membrane secretin SsaC; Provisional; Region: PRK15346
544404012921	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
544404012922	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
544404012923	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
544404012924	Tetratricopeptide repeat; Region: TPR_3; pfam07720
544404012925	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
544404012926	negative regulator GrlR; Provisional; Region: PRK14051
544404012927	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
544404012928	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404012929	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404012930	catalytic residue [active]
544404012931	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
544404012932	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
544404012933	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
544404012934	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
544404012935	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
544404012936	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
544404012937	Type III secretion system filament chaperone CesA; Region: CesA; pfam11439
544404012938	type III secretion system protein, YseE family; Region: type_III_yscE; TIGR02501
544404012939	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
544404012940	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
544404012941	EspG protein; Region: EspG; pfam06872
544404012942	SdiA-regulated; Region: SdiA-regulated; cd09971
544404012943	SdiA-regulated; Region: SdiA-regulated; pfam06977
544404012944	putative active site [active]
544404012945	EamA-like transporter family; Region: EamA; pfam00892
544404012946	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
544404012947	EamA-like transporter family; Region: EamA; pfam00892
544404012948	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
544404012949	lipoprotein, YaeC family; Region: TIGR00363
544404012950	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
544404012951	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012952	putative substrate translocation pore; other site
544404012953	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
544404012954	Predicted transcriptional regulator [Transcription]; Region: COG2944
544404012955	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404012956	non-specific DNA binding site [nucleotide binding]; other site
544404012957	salt bridge; other site
544404012958	sequence-specific DNA binding site [nucleotide binding]; other site
544404012959	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
544404012960	cryptic adenine deaminase; Provisional; Region: PRK10027
544404012961	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
544404012962	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
544404012963	active site
544404012964	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
544404012965	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
544404012966	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012967	putative substrate translocation pore; other site
544404012968	regulatory protein UhpC; Provisional; Region: PRK11663
544404012969	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012970	putative substrate translocation pore; other site
544404012971	sensory histidine kinase UhpB; Provisional; Region: PRK11644
544404012972	MASE1; Region: MASE1; pfam05231
544404012973	Histidine kinase; Region: HisKA_3; pfam07730
544404012974	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
544404012975	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404012976	active site
544404012977	phosphorylation site [posttranslational modification]
544404012978	intermolecular recognition site; other site
544404012979	dimerization interface [polypeptide binding]; other site
544404012980	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404012981	DNA binding residues [nucleotide binding]
544404012982	dimerization interface [polypeptide binding]; other site
544404012983	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
544404012984	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
544404012985	putative valine binding site [chemical binding]; other site
544404012986	dimer interface [polypeptide binding]; other site
544404012987	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
544404012988	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
544404012989	PYR/PP interface [polypeptide binding]; other site
544404012990	dimer interface [polypeptide binding]; other site
544404012991	TPP binding site [chemical binding]; other site
544404012992	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
544404012993	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
544404012994	TPP-binding site [chemical binding]; other site
544404012995	dimer interface [polypeptide binding]; other site
544404012996	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
544404012997	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404012998	putative substrate translocation pore; other site
544404012999	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
544404013000	Domain of unknown function (DUF202); Region: DUF202; pfam02656
544404013001	Predicted membrane protein [Function unknown]; Region: COG2149
544404013002	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
544404013003	Sulfatase; Region: Sulfatase; pfam00884
544404013004	putative transporter; Provisional; Region: PRK10484
544404013005	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
544404013006	Na binding site [ion binding]; other site
544404013007	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
544404013008	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404013009	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404013010	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
544404013011	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
544404013012	NAD binding site [chemical binding]; other site
544404013013	sugar binding site [chemical binding]; other site
544404013014	divalent metal binding site [ion binding]; other site
544404013015	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404013016	dimer interface [polypeptide binding]; other site
544404013017	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
544404013018	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
544404013019	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404013020	active site turn [active]
544404013021	phosphorylation site [posttranslational modification]
544404013022	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
544404013023	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404013024	DNA-binding site [nucleotide binding]; DNA binding site
544404013025	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
544404013026	putative transporter; Validated; Region: PRK03818
544404013027	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
544404013028	TrkA-C domain; Region: TrkA_C; pfam02080
544404013029	TrkA-C domain; Region: TrkA_C; pfam02080
544404013030	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
544404013031	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
544404013032	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
544404013033	putative dimer interface [polypeptide binding]; other site
544404013034	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
544404013035	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
544404013036	putative dimer interface [polypeptide binding]; other site
544404013037	hypothetical protein; Provisional; Region: PRK11616
544404013038	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
544404013039	putative oxidoreductase; Provisional; Region: PRK11445
544404013040	hypothetical protein; Provisional; Region: PRK07236
544404013041	hypothetical protein; Provisional; Region: PRK10215
544404013042	sugar phosphate phosphatase; Provisional; Region: PRK10513
544404013043	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013044	active site
544404013045	motif I; other site
544404013046	motif II; other site
544404013047	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013048	hypothetical protein; Provisional; Region: PRK11426
544404013049	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
544404013050	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404013051	Mg2+ binding site [ion binding]; other site
544404013052	G-X-G motif; other site
544404013053	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
544404013054	anchoring element; other site
544404013055	dimer interface [polypeptide binding]; other site
544404013056	ATP binding site [chemical binding]; other site
544404013057	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
544404013058	active site
544404013059	putative metal-binding site [ion binding]; other site
544404013060	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
544404013061	recF protein; Region: recf; TIGR00611
544404013062	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404013063	Walker A/P-loop; other site
544404013064	ATP binding site [chemical binding]; other site
544404013065	Q-loop/lid; other site
544404013066	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404013067	ABC transporter signature motif; other site
544404013068	Walker B; other site
544404013069	D-loop; other site
544404013070	H-loop/switch region; other site
544404013071	DNA polymerase III subunit beta; Validated; Region: PRK05643
544404013072	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
544404013073	putative DNA binding surface [nucleotide binding]; other site
544404013074	dimer interface [polypeptide binding]; other site
544404013075	beta-clamp/clamp loader binding surface; other site
544404013076	beta-clamp/translesion DNA polymerase binding surface; other site
544404013077	DnaA N-terminal domain; Region: DnaA_N; pfam11638
544404013078	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
544404013079	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404013080	Walker A motif; other site
544404013081	ATP binding site [chemical binding]; other site
544404013082	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
544404013083	Walker B motif; other site
544404013084	arginine finger; other site
544404013085	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
544404013086	DnaA box-binding interface [nucleotide binding]; other site
544404013087	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
544404013088	ribonuclease P; Reviewed; Region: rnpA; PRK01732
544404013089	membrane protein insertase; Provisional; Region: PRK01318
544404013090	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
544404013091	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
544404013092	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
544404013093	trmE is a tRNA modification GTPase; Region: trmE; cd04164
544404013094	G1 box; other site
544404013095	GTP/Mg2+ binding site [chemical binding]; other site
544404013096	Switch I region; other site
544404013097	G2 box; other site
544404013098	Switch II region; other site
544404013099	G3 box; other site
544404013100	G4 box; other site
544404013101	G5 box; other site
544404013102	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
544404013103	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
544404013104	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
544404013105	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
544404013106	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
544404013107	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
544404013108	catalytic residue [active]
544404013109	tryptophan permease TnaB; Provisional; Region: PRK09664
544404013110	aromatic amino acid transport protein; Region: araaP; TIGR00837
544404013111	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
544404013112	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404013113	putative substrate translocation pore; other site
544404013114	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
544404013115	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404013116	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
544404013117	substrate binding pocket [chemical binding]; other site
544404013118	dimerization interface [polypeptide binding]; other site
544404013119	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
544404013120	Predicted flavoprotein [General function prediction only]; Region: COG0431
544404013121	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
544404013122	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
544404013123	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
544404013124	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013125	active site
544404013126	motif I; other site
544404013127	motif II; other site
544404013128	transcriptional regulator PhoU; Provisional; Region: PRK11115
544404013129	PhoU domain; Region: PhoU; pfam01895
544404013130	PhoU domain; Region: PhoU; pfam01895
544404013131	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
544404013132	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
544404013133	Walker A/P-loop; other site
544404013134	ATP binding site [chemical binding]; other site
544404013135	Q-loop/lid; other site
544404013136	ABC transporter signature motif; other site
544404013137	Walker B; other site
544404013138	D-loop; other site
544404013139	H-loop/switch region; other site
544404013140	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
544404013141	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404013142	dimer interface [polypeptide binding]; other site
544404013143	conserved gate region; other site
544404013144	putative PBP binding loops; other site
544404013145	ABC-ATPase subunit interface; other site
544404013146	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
544404013147	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404013148	dimer interface [polypeptide binding]; other site
544404013149	conserved gate region; other site
544404013150	putative PBP binding loops; other site
544404013151	ABC-ATPase subunit interface; other site
544404013152	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404013153	Fimbrial protein; Region: Fimbrial; cl01416
544404013154	Fimbrial protein; Region: Fimbrial; cl01416
544404013155	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
544404013156	PapC N-terminal domain; Region: PapC_N; pfam13954
544404013157	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404013158	PapC C-terminal domain; Region: PapC_C; pfam13953
544404013159	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404013160	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404013161	fimbrial protein; Provisional; Region: lpfA; PRK15289
544404013162	similar to hypothetical protein
544404013163	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
544404013164	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
544404013165	glutaminase active site [active]
544404013166	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
544404013167	dimer interface [polypeptide binding]; other site
544404013168	active site
544404013169	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
544404013170	dimer interface [polypeptide binding]; other site
544404013171	active site
544404013172	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
544404013173	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
544404013174	Substrate binding site; other site
544404013175	Mg++ binding site; other site
544404013176	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
544404013177	active site
544404013178	substrate binding site [chemical binding]; other site
544404013179	CoA binding site [chemical binding]; other site
544404013180	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
544404013181	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
544404013182	gamma subunit interface [polypeptide binding]; other site
544404013183	epsilon subunit interface [polypeptide binding]; other site
544404013184	LBP interface [polypeptide binding]; other site
544404013185	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
544404013186	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
544404013187	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
544404013188	alpha subunit interaction interface [polypeptide binding]; other site
544404013189	Walker A motif; other site
544404013190	ATP binding site [chemical binding]; other site
544404013191	Walker B motif; other site
544404013192	inhibitor binding site; inhibition site
544404013193	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
544404013194	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
544404013195	core domain interface [polypeptide binding]; other site
544404013196	delta subunit interface [polypeptide binding]; other site
544404013197	epsilon subunit interface [polypeptide binding]; other site
544404013198	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
544404013199	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
544404013200	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
544404013201	beta subunit interaction interface [polypeptide binding]; other site
544404013202	Walker A motif; other site
544404013203	ATP binding site [chemical binding]; other site
544404013204	Walker B motif; other site
544404013205	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
544404013206	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
544404013207	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
544404013208	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
544404013209	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
544404013210	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
544404013211	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
544404013212	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
544404013213	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
544404013214	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
544404013215	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404013216	S-adenosylmethionine binding site [chemical binding]; other site
544404013217	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
544404013218	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
544404013219	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
544404013220	FMN-binding protein MioC; Provisional; Region: PRK09004
544404013221	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
544404013222	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404013223	putative DNA binding site [nucleotide binding]; other site
544404013224	putative Zn2+ binding site [ion binding]; other site
544404013225	AsnC family; Region: AsnC_trans_reg; pfam01037
544404013226	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
544404013227	dimer interface [polypeptide binding]; other site
544404013228	active site
544404013229	hypothetical protein; Provisional; Region: yieM; PRK10997
544404013230	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
544404013231	metal ion-dependent adhesion site (MIDAS); other site
544404013232	regulatory ATPase RavA; Provisional; Region: PRK13531
544404013233	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404013234	Walker A motif; other site
544404013235	ATP binding site [chemical binding]; other site
544404013236	Walker B motif; other site
544404013237	arginine finger; other site
544404013238	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
544404013239	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
544404013240	potassium uptake protein; Region: kup; TIGR00794
544404013241	D-ribose pyranase; Provisional; Region: PRK11797
544404013242	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
544404013243	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404013244	Walker A/P-loop; other site
544404013245	ATP binding site [chemical binding]; other site
544404013246	Q-loop/lid; other site
544404013247	ABC transporter signature motif; other site
544404013248	Walker B; other site
544404013249	D-loop; other site
544404013250	H-loop/switch region; other site
544404013251	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404013252	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404013253	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404013254	TM-ABC transporter signature motif; other site
544404013255	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
544404013256	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
544404013257	ligand binding site [chemical binding]; other site
544404013258	dimerization interface [polypeptide binding]; other site
544404013259	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
544404013260	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404013261	substrate binding site [chemical binding]; other site
544404013262	dimer interface [polypeptide binding]; other site
544404013263	ATP binding site [chemical binding]; other site
544404013264	transcriptional repressor RbsR; Provisional; Region: PRK10423
544404013265	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404013266	DNA binding site [nucleotide binding]
544404013267	domain linker motif; other site
544404013268	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
544404013269	dimerization interface [polypeptide binding]; other site
544404013270	ligand binding site [chemical binding]; other site
544404013271	putative transporter; Provisional; Region: PRK10504
544404013272	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404013273	putative substrate translocation pore; other site
544404013274	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404013275	Transcriptional regulators [Transcription]; Region: FadR; COG2186
544404013276	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404013277	DNA-binding site [nucleotide binding]; DNA binding site
544404013278	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
544404013279	transcriptional regulator HdfR; Provisional; Region: PRK03601
544404013280	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404013281	LysR substrate binding domain; Region: LysR_substrate; pfam03466
544404013282	dimerization interface [polypeptide binding]; other site
544404013283	hypothetical protein; Provisional; Region: PRK11027
544404013284	putative ATP-dependent protease; Provisional; Region: PRK09862
544404013285	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
544404013286	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404013287	Walker A motif; other site
544404013288	ATP binding site [chemical binding]; other site
544404013289	Walker B motif; other site
544404013290	arginine finger; other site
544404013291	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
544404013292	ilvG operon leader peptide; Provisional; Region: PRK10424
544404013293	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
544404013294	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
544404013295	PYR/PP interface [polypeptide binding]; other site
544404013296	dimer interface [polypeptide binding]; other site
544404013297	TPP binding site [chemical binding]; other site
544404013298	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
544404013299	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
544404013300	TPP-binding site [chemical binding]; other site
544404013301	dimer interface [polypeptide binding]; other site
544404013302	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
544404013303	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
544404013304	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
544404013305	homodimer interface [polypeptide binding]; other site
544404013306	substrate-cofactor binding pocket; other site
544404013307	catalytic residue [active]
544404013308	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
544404013309	threonine dehydratase; Reviewed; Region: PRK09224
544404013310	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
544404013311	tetramer interface [polypeptide binding]; other site
544404013312	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404013313	catalytic residue [active]
544404013314	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
544404013315	putative Ile/Val binding site [chemical binding]; other site
544404013316	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
544404013317	putative Ile/Val binding site [chemical binding]; other site
544404013318	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404013319	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
544404013320	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
544404013321	putative dimerization interface [polypeptide binding]; other site
544404013322	ketol-acid reductoisomerase; Validated; Region: PRK05225
544404013323	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
544404013324	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
544404013325	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
544404013326	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
544404013327	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
544404013328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
544404013329	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
544404013330	Part of AAA domain; Region: AAA_19; pfam13245
544404013331	Family description; Region: UvrD_C_2; pfam13538
544404013332	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
544404013333	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
544404013334	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
544404013335	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
544404013336	ATP binding site [chemical binding]; other site
544404013337	Mg++ binding site [ion binding]; other site
544404013338	motif III; other site
544404013339	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404013340	nucleotide binding region [chemical binding]; other site
544404013341	ATP-binding site [chemical binding]; other site
544404013342	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
544404013343	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
544404013344	catalytic residues [active]
544404013345	transcription termination factor Rho; Provisional; Region: rho; PRK09376
544404013346	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
544404013347	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
544404013348	RNA binding site [nucleotide binding]; other site
544404013349	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
544404013350	multimer interface [polypeptide binding]; other site
544404013351	Walker A motif; other site
544404013352	ATP binding site [chemical binding]; other site
544404013353	Walker B motif; other site
544404013354	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
544404013355	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
544404013356	Mg++ binding site [ion binding]; other site
544404013357	putative catalytic motif [active]
544404013358	substrate binding site [chemical binding]; other site
544404013359	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
544404013360	Chain length determinant protein; Region: Wzz; pfam02706
544404013361	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
544404013362	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
544404013363	active site
544404013364	homodimer interface [polypeptide binding]; other site
544404013365	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
544404013366	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
544404013367	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
544404013368	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
544404013369	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
544404013370	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
544404013371	NAD binding site [chemical binding]; other site
544404013372	substrate binding site [chemical binding]; other site
544404013373	homodimer interface [polypeptide binding]; other site
544404013374	active site
544404013375	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
544404013376	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
544404013377	substrate binding site; other site
544404013378	tetramer interface; other site
544404013379	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
544404013380	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
544404013381	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
544404013382	inhibitor-cofactor binding pocket; inhibition site
544404013383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404013384	catalytic residue [active]
544404013385	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
544404013386	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
544404013387	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
544404013388	putative common antigen polymerase; Provisional; Region: PRK02975
544404013389	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
544404013390	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
544404013391	putative transport protein YifK; Provisional; Region: PRK10746
544404013392	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
544404013393	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404013394	FeS/SAM binding site; other site
544404013395	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
544404013396	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
544404013397	Sulfatase; Region: Sulfatase; pfam00884
544404013398	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
544404013399	HemY protein N-terminus; Region: HemY_N; pfam07219
544404013400	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
544404013401	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
544404013402	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
544404013403	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
544404013404	active site
544404013405	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
544404013406	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
544404013407	domain interfaces; other site
544404013408	active site
544404013409	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
544404013410	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
544404013411	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
544404013412	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
544404013413	putative iron binding site [ion binding]; other site
544404013414	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
544404013415	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
544404013416	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
544404013417	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
544404013418	hypothetical protein; Provisional; Region: PRK10963
544404013419	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
544404013420	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404013421	active site
544404013422	DNA binding site [nucleotide binding]
544404013423	Int/Topo IB signature motif; other site
544404013424	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
544404013425	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013426	motif II; other site
544404013427	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
544404013428	Part of AAA domain; Region: AAA_19; pfam13245
544404013429	Family description; Region: UvrD_C_2; pfam13538
544404013430	Uncharacterized conserved protein [Function unknown]; Region: COG1912
544404013431	Predicted periplasmic protein [Function unknown]; Region: COG3698
544404013432	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
544404013433	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
544404013434	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
544404013435	Cl binding site [ion binding]; other site
544404013436	oligomer interface [polypeptide binding]; other site
544404013437	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
544404013438	conserved hypothetical protein; Region: TIGR03034
544404013439	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
544404013440	EamA-like transporter family; Region: EamA; pfam00892
544404013441	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
544404013442	CoenzymeA binding site [chemical binding]; other site
544404013443	subunit interaction site [polypeptide binding]; other site
544404013444	PHB binding site; other site
544404013445	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
544404013446	dimerization interface [polypeptide binding]; other site
544404013447	substrate binding site [chemical binding]; other site
544404013448	active site
544404013449	calcium binding site [ion binding]; other site
544404013450	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
544404013451	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404013452	ATP binding site [chemical binding]; other site
544404013453	putative Mg++ binding site [ion binding]; other site
544404013454	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404013455	nucleotide binding region [chemical binding]; other site
544404013456	ATP-binding site [chemical binding]; other site
544404013457	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
544404013458	Helicase and RNase D C-terminal; Region: HRDC; smart00341
544404013459	threonine efflux system; Provisional; Region: PRK10229
544404013460	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
544404013461	lysophospholipase L2; Provisional; Region: PRK10749
544404013462	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
544404013463	putative hydrolase; Provisional; Region: PRK10976
544404013464	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013465	active site
544404013466	motif I; other site
544404013467	motif II; other site
544404013468	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013469	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
544404013470	EamA-like transporter family; Region: EamA; pfam00892
544404013471	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
544404013472	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404013473	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
544404013474	putative dimerization interface [polypeptide binding]; other site
544404013475	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
544404013476	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
544404013477	THF binding site; other site
544404013478	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
544404013479	substrate binding site [chemical binding]; other site
544404013480	THF binding site; other site
544404013481	zinc-binding site [ion binding]; other site
544404013482	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
544404013483	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
544404013484	uridine phosphorylase; Provisional; Region: PRK11178
544404013485	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
544404013486	DNA recombination protein RmuC; Provisional; Region: PRK10361
544404013487	RmuC family; Region: RmuC; pfam02646
544404013488	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
544404013489	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404013490	S-adenosylmethionine binding site [chemical binding]; other site
544404013491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
544404013492	SCP-2 sterol transfer family; Region: SCP2; pfam02036
544404013493	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
544404013494	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
544404013495	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
544404013496	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
544404013497	sec-independent translocase; Provisional; Region: PRK01770
544404013498	sec-independent translocase; Provisional; Region: tatB; PRK00404
544404013499	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
544404013500	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
544404013501	active site
544404013502	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
544404013503	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
544404013504	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
544404013505	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
544404013506	FMN reductase; Validated; Region: fre; PRK08051
544404013507	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
544404013508	FAD binding pocket [chemical binding]; other site
544404013509	FAD binding motif [chemical binding]; other site
544404013510	phosphate binding motif [ion binding]; other site
544404013511	beta-alpha-beta structure motif; other site
544404013512	NAD binding pocket [chemical binding]; other site
544404013513	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
544404013514	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
544404013515	dimer interface [polypeptide binding]; other site
544404013516	active site
544404013517	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
544404013518	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
544404013519	substrate binding site [chemical binding]; other site
544404013520	oxyanion hole (OAH) forming residues; other site
544404013521	trimer interface [polypeptide binding]; other site
544404013522	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
544404013523	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
544404013524	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
544404013525	proline dipeptidase; Provisional; Region: PRK13607
544404013526	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
544404013527	active site
544404013528	hypothetical protein; Provisional; Region: PRK11568
544404013529	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
544404013530	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
544404013531	potassium transporter; Provisional; Region: PRK10750
544404013532	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
544404013533	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
544404013534	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
544404013535	Walker A motif; other site
544404013536	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
544404013537	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
544404013538	GTP binding site; other site
544404013539	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
544404013540	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
544404013541	serine/threonine protein kinase; Provisional; Region: PRK11768
544404013542	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
544404013543	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
544404013544	catalytic residues [active]
544404013545	hinge region; other site
544404013546	alpha helical domain; other site
544404013547	hypothetical protein; Provisional; Region: PRK11367
544404013548	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
544404013549	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
544404013550	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
544404013551	putative acyl-acceptor binding pocket; other site
544404013552	DNA polymerase I; Provisional; Region: PRK05755
544404013553	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
544404013554	active site
544404013555	metal binding site 1 [ion binding]; metal-binding site
544404013556	putative 5' ssDNA interaction site; other site
544404013557	metal binding site 3; metal-binding site
544404013558	metal binding site 2 [ion binding]; metal-binding site
544404013559	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
544404013560	putative DNA binding site [nucleotide binding]; other site
544404013561	putative metal binding site [ion binding]; other site
544404013562	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
544404013563	active site
544404013564	catalytic site [active]
544404013565	substrate binding site [chemical binding]; other site
544404013566	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
544404013567	active site
544404013568	DNA binding site [nucleotide binding]
544404013569	catalytic site [active]
544404013570	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
544404013571	G1 box; other site
544404013572	GTP/Mg2+ binding site [chemical binding]; other site
544404013573	Switch I region; other site
544404013574	G2 box; other site
544404013575	G3 box; other site
544404013576	Switch II region; other site
544404013577	G4 box; other site
544404013578	G5 box; other site
544404013579	similar to hypothetical protein
544404013580	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
544404013581	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
544404013582	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404013583	FeS/SAM binding site; other site
544404013584	HemN C-terminal domain; Region: HemN_C; pfam06969
544404013585	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
544404013586	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404013587	active site
544404013588	phosphorylation site [posttranslational modification]
544404013589	intermolecular recognition site; other site
544404013590	dimerization interface [polypeptide binding]; other site
544404013591	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404013592	Walker A motif; other site
544404013593	ATP binding site [chemical binding]; other site
544404013594	Walker B motif; other site
544404013595	arginine finger; other site
544404013596	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
544404013597	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
544404013598	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
544404013599	putative active site [active]
544404013600	heme pocket [chemical binding]; other site
544404013601	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404013602	dimer interface [polypeptide binding]; other site
544404013603	phosphorylation site [posttranslational modification]
544404013604	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404013605	ATP binding site [chemical binding]; other site
544404013606	Mg2+ binding site [ion binding]; other site
544404013607	G-X-G motif; other site
544404013608	glutamine synthetase; Provisional; Region: glnA; PRK09469
544404013609	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
544404013610	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
544404013611	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
544404013612	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
544404013613	G1 box; other site
544404013614	putative GEF interaction site [polypeptide binding]; other site
544404013615	GTP/Mg2+ binding site [chemical binding]; other site
544404013616	Switch I region; other site
544404013617	G2 box; other site
544404013618	G3 box; other site
544404013619	Switch II region; other site
544404013620	G4 box; other site
544404013621	G5 box; other site
544404013622	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
544404013623	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
544404013624	transcriptional regulator protein; Region: phnR; TIGR03337
544404013625	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404013626	DNA-binding site [nucleotide binding]; DNA binding site
544404013627	UTRA domain; Region: UTRA; pfam07702
544404013628	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
544404013629	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404013630	putative substrate translocation pore; other site
544404013631	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404013632	outer membrane porin L; Provisional; Region: ompL; PRK09980
544404013633	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
544404013634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404013635	putative substrate translocation pore; other site
544404013636	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
544404013637	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
544404013638	alpha-glucosidase; Provisional; Region: PRK10426
544404013639	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
544404013640	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
544404013641	putative active site [active]
544404013642	putative catalytic site [active]
544404013643	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
544404013644	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
544404013645	active site
544404013646	catalytic residues [active]
544404013647	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
544404013648	dimerization interface [polypeptide binding]; other site
544404013649	putative active cleft [active]
544404013650	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
544404013651	catalytic residue [active]
544404013652	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
544404013653	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
544404013654	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404013655	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
544404013656	substrate binding site [chemical binding]; other site
544404013657	ATP binding site [chemical binding]; other site
544404013658	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
544404013659	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404013660	putative DNA binding site [nucleotide binding]; other site
544404013661	putative Zn2+ binding site [ion binding]; other site
544404013662	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404013663	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
544404013664	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404013665	motif II; other site
544404013666	hypothetical protein; Reviewed; Region: PRK01637
544404013667	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
544404013668	putative active site [active]
544404013669	dimerization interface [polypeptide binding]; other site
544404013670	putative tRNAtyr binding site [nucleotide binding]; other site
544404013671	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404013672	Coenzyme A binding pocket [chemical binding]; other site
544404013673	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
544404013674	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
544404013675	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
544404013676	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
544404013677	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
544404013678	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
544404013679	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
544404013680	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
544404013681	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404013682	molybdopterin cofactor binding site; other site
544404013683	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
544404013684	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
544404013685	molybdopterin cofactor binding site; other site
544404013686	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404013687	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
544404013688	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
544404013689	putative frv operon regulatory protein; Provisional; Region: PRK09863
544404013690	HTH domain; Region: HTH_11; pfam08279
544404013691	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404013692	active site
544404013693	phosphorylation site [posttranslational modification]
544404013694	putative peptidase; Provisional; Region: PRK09864
544404013695	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
544404013696	oligomer interface [polypeptide binding]; other site
544404013697	active site
544404013698	metal binding site [ion binding]; metal-binding site
544404013699	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
544404013700	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
544404013701	active site
544404013702	P-loop; other site
544404013703	phosphorylation site [posttranslational modification]
544404013704	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
544404013705	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404013706	active site
544404013707	phosphorylation site [posttranslational modification]
544404013708	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
544404013709	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
544404013710	intersubunit interface [polypeptide binding]; other site
544404013711	active site
544404013712	Zn2+ binding site [ion binding]; other site
544404013713	L-rhamnose isomerase; Provisional; Region: PRK01076
544404013714	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
544404013715	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
544404013716	N- and C-terminal domain interface [polypeptide binding]; other site
544404013717	active site
544404013718	putative catalytic site [active]
544404013719	metal binding site [ion binding]; metal-binding site
544404013720	ATP binding site [chemical binding]; other site
544404013721	rhamnulokinase; Provisional; Region: rhaB; PRK10640
544404013722	carbohydrate binding site [chemical binding]; other site
544404013723	transcriptional activator RhaS; Provisional; Region: PRK13503
544404013724	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
544404013725	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404013726	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404013727	transcriptional activator RhaR; Provisional; Region: PRK13500
544404013728	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
544404013729	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404013730	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404013731	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
544404013732	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
544404013733	superoxide dismutase; Provisional; Region: PRK10925
544404013734	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
544404013735	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
544404013736	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
544404013737	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
544404013738	MOSC domain; Region: MOSC; pfam03473
544404013739	3-alpha domain; Region: 3-alpha; pfam03475
544404013740	two-component sensor protein; Provisional; Region: cpxA; PRK09470
544404013741	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404013742	dimerization interface [polypeptide binding]; other site
544404013743	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404013744	dimer interface [polypeptide binding]; other site
544404013745	phosphorylation site [posttranslational modification]
544404013746	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404013747	ATP binding site [chemical binding]; other site
544404013748	Mg2+ binding site [ion binding]; other site
544404013749	G-X-G motif; other site
544404013750	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
544404013751	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404013752	active site
544404013753	intermolecular recognition site; other site
544404013754	dimerization interface [polypeptide binding]; other site
544404013755	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404013756	DNA binding site [nucleotide binding]
544404013757	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
544404013758	dimer interface [polypeptide binding]; other site
544404013759	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
544404013760	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
544404013761	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
544404013762	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
544404013763	active site
544404013764	ADP/pyrophosphate binding site [chemical binding]; other site
544404013765	dimerization interface [polypeptide binding]; other site
544404013766	allosteric effector site; other site
544404013767	fructose-1,6-bisphosphate binding site; other site
544404013768	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
544404013769	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
544404013770	substrate binding pocket [chemical binding]; other site
544404013771	membrane-bound complex binding site; other site
544404013772	hinge residues; other site
544404013773	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
544404013774	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
544404013775	triosephosphate isomerase; Provisional; Region: PRK14567
544404013776	substrate binding site [chemical binding]; other site
544404013777	dimer interface [polypeptide binding]; other site
544404013778	catalytic triad [active]
544404013779	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
544404013780	Predicted membrane protein [Function unknown]; Region: COG3152
544404013781	hypothetical protein; Provisional; Region: PRK09981
544404013782	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
544404013783	Ligand Binding Site [chemical binding]; other site
544404013784	ferredoxin-NADP reductase; Provisional; Region: PRK10926
544404013785	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
544404013786	FAD binding pocket [chemical binding]; other site
544404013787	FAD binding motif [chemical binding]; other site
544404013788	phosphate binding motif [ion binding]; other site
544404013789	beta-alpha-beta structure motif; other site
544404013790	NAD binding pocket [chemical binding]; other site
544404013791	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
544404013792	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
544404013793	putative active site [active]
544404013794	glycerol kinase; Provisional; Region: glpK; PRK00047
544404013795	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
544404013796	N- and C-terminal domain interface [polypeptide binding]; other site
544404013797	active site
544404013798	MgATP binding site [chemical binding]; other site
544404013799	catalytic site [active]
544404013800	metal binding site [ion binding]; metal-binding site
544404013801	glycerol binding site [chemical binding]; other site
544404013802	homotetramer interface [polypeptide binding]; other site
544404013803	homodimer interface [polypeptide binding]; other site
544404013804	FBP binding site [chemical binding]; other site
544404013805	protein IIAGlc interface [polypeptide binding]; other site
544404013806	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
544404013807	amphipathic channel; other site
544404013808	Asn-Pro-Ala signature motifs; other site
544404013809	septal ring assembly protein ZapB; Provisional; Region: PRK15422
544404013810	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
544404013811	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
544404013812	UbiA prenyltransferase family; Region: UbiA; pfam01040
544404013813	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
544404013814	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404013815	Walker A motif; other site
544404013816	ATP binding site [chemical binding]; other site
544404013817	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
544404013818	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
544404013819	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
544404013820	active site
544404013821	HslU subunit interaction site [polypeptide binding]; other site
544404013822	essential cell division protein FtsN; Provisional; Region: PRK10927
544404013823	cell division protein FtsN; Provisional; Region: PRK12757
544404013824	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404013825	DNA binding site [nucleotide binding]
544404013826	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
544404013827	domain linker motif; other site
544404013828	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
544404013829	dimerization interface [polypeptide binding]; other site
544404013830	ligand binding site [chemical binding]; other site
544404013831	primosome assembly protein PriA; Validated; Region: PRK05580
544404013832	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404013833	ATP binding site [chemical binding]; other site
544404013834	putative Mg++ binding site [ion binding]; other site
544404013835	helicase superfamily c-terminal domain; Region: HELICc; smart00490
544404013836	ATP-binding site [chemical binding]; other site
544404013837	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
544404013838	RHS Repeat; Region: RHS_repeat; pfam05593
544404013839	RHS Repeat; Region: RHS_repeat; pfam05593
544404013840	RHS Repeat; Region: RHS_repeat; pfam05593
544404013841	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
544404013842	RHS Repeat; Region: RHS_repeat; pfam05593
544404013843	RHS Repeat; Region: RHS_repeat; pfam05593
544404013844	RHS protein; Region: RHS; pfam03527
544404013845	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
544404013846	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
544404013847	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
544404013848	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
544404013849	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
544404013850	hypothetical protein; Provisional; Region: PRK10030
544404013851	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
544404013852	dimerization interface [polypeptide binding]; other site
544404013853	DNA binding site [nucleotide binding]
544404013854	corepressor binding sites; other site
544404013855	cystathionine gamma-synthase; Provisional; Region: PRK08045
544404013856	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
544404013857	homodimer interface [polypeptide binding]; other site
544404013858	substrate-cofactor binding pocket; other site
544404013859	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404013860	catalytic residue [active]
544404013861	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
544404013862	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
544404013863	putative catalytic residues [active]
544404013864	putative nucleotide binding site [chemical binding]; other site
544404013865	putative aspartate binding site [chemical binding]; other site
544404013866	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
544404013867	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
544404013868	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
544404013869	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
544404013870	FAD binding site [chemical binding]; other site
544404013871	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
544404013872	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
544404013873	heme binding site [chemical binding]; other site
544404013874	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
544404013875	EamA-like transporter family; Region: EamA; pfam00892
544404013876	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
544404013877	EamA-like transporter family; Region: EamA; pfam00892
544404013878	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
544404013879	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
544404013880	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
544404013881	dimer interface [polypeptide binding]; other site
544404013882	active site
544404013883	metal binding site [ion binding]; metal-binding site
544404013884	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
544404013885	active site
544404013886	intersubunit interactions; other site
544404013887	catalytic residue [active]
544404013888	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
544404013889	dimerization domain swap beta strand [polypeptide binding]; other site
544404013890	regulatory protein interface [polypeptide binding]; other site
544404013891	active site
544404013892	regulatory phosphorylation site [posttranslational modification]; other site
544404013893	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
544404013894	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
544404013895	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
544404013896	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
544404013897	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404013898	active site
544404013899	phosphorylation site [posttranslational modification]
544404013900	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
544404013901	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
544404013902	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
544404013903	active site
544404013904	P-loop; other site
544404013905	phosphorylation site [posttranslational modification]
544404013906	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
544404013907	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
544404013908	dimer interface [polypeptide binding]; other site
544404013909	active site
544404013910	glycine loop; other site
544404013911	pyruvate formate lyase II activase; Provisional; Region: PRK10076
544404013912	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
544404013913	active site
544404013914	P-loop; other site
544404013915	phosphorylation site [posttranslational modification]
544404013916	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404013917	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404013918	hypothetical protein; Provisional; Region: PRK10649
544404013919	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
544404013920	Sulfatase; Region: Sulfatase; pfam00884
544404013921	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
544404013922	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
544404013923	acetylornithine deacetylase; Provisional; Region: PRK05111
544404013924	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
544404013925	metal binding site [ion binding]; metal-binding site
544404013926	putative dimer interface [polypeptide binding]; other site
544404013927	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
544404013928	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
544404013929	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
544404013930	nucleotide binding site [chemical binding]; other site
544404013931	N-acetyl-L-glutamate binding site [chemical binding]; other site
544404013932	argininosuccinate lyase; Provisional; Region: PRK04833
544404013933	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
544404013934	active sites [active]
544404013935	tetramer interface [polypeptide binding]; other site
544404013936	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
544404013937	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
544404013938	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
544404013939	dimerization interface [polypeptide binding]; other site
544404013940	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
544404013941	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
544404013942	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
544404013943	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
544404013944	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
544404013945	metal binding site [ion binding]; metal-binding site
544404013946	putative dimer interface [polypeptide binding]; other site
544404013947	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404013948	metabolite-proton symporter; Region: 2A0106; TIGR00883
544404013949	putative substrate translocation pore; other site
544404013950	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
544404013951	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404013952	hypothetical protein; Provisional; Region: PRK11056
544404013953	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
544404013954	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404013955	S-adenosylmethionine binding site [chemical binding]; other site
544404013956	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
544404013957	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
544404013958	N-terminal plug; other site
544404013959	ligand-binding site [chemical binding]; other site
544404013960	glutamate racemase; Provisional; Region: PRK00865
544404013961	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
544404013962	FAD binding domain; Region: FAD_binding_4; pfam01565
544404013963	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
544404013964	Biotin operon repressor [Transcription]; Region: BirA; COG1654
544404013965	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
544404013966	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
544404013967	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
544404013968	pantothenate kinase; Provisional; Region: PRK05439
544404013969	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
544404013970	ATP-binding site [chemical binding]; other site
544404013971	CoA-binding site [chemical binding]; other site
544404013972	Mg2+-binding site [ion binding]; other site
544404013973	elongation factor Tu; Reviewed; Region: PRK00049
544404013974	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
544404013975	G1 box; other site
544404013976	GEF interaction site [polypeptide binding]; other site
544404013977	GTP/Mg2+ binding site [chemical binding]; other site
544404013978	Switch I region; other site
544404013979	G2 box; other site
544404013980	G3 box; other site
544404013981	Switch II region; other site
544404013982	G4 box; other site
544404013983	G5 box; other site
544404013984	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
544404013985	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
544404013986	Antibiotic Binding Site [chemical binding]; other site
544404013987	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
544404013988	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
544404013989	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
544404013990	putative homodimer interface [polypeptide binding]; other site
544404013991	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
544404013992	heterodimer interface [polypeptide binding]; other site
544404013993	homodimer interface [polypeptide binding]; other site
544404013994	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
544404013995	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
544404013996	23S rRNA interface [nucleotide binding]; other site
544404013997	L7/L12 interface [polypeptide binding]; other site
544404013998	putative thiostrepton binding site; other site
544404013999	L25 interface [polypeptide binding]; other site
544404014000	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
544404014001	mRNA/rRNA interface [nucleotide binding]; other site
544404014002	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
544404014003	23S rRNA interface [nucleotide binding]; other site
544404014004	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
544404014005	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
544404014006	core dimer interface [polypeptide binding]; other site
544404014007	peripheral dimer interface [polypeptide binding]; other site
544404014008	L10 interface [polypeptide binding]; other site
544404014009	L11 interface [polypeptide binding]; other site
544404014010	putative EF-Tu interaction site [polypeptide binding]; other site
544404014011	putative EF-G interaction site [polypeptide binding]; other site
544404014012	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
544404014013	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
544404014014	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
544404014015	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
544404014016	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
544404014017	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
544404014018	RPB3 interaction site [polypeptide binding]; other site
544404014019	RPB1 interaction site [polypeptide binding]; other site
544404014020	RPB11 interaction site [polypeptide binding]; other site
544404014021	RPB10 interaction site [polypeptide binding]; other site
544404014022	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
544404014023	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
544404014024	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
544404014025	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
544404014026	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
544404014027	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
544404014028	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
544404014029	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
544404014030	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
544404014031	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
544404014032	DNA binding site [nucleotide binding]
544404014033	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
544404014034	stationary phase growth adaptation protein; Provisional; Region: PRK09717
544404014035	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
544404014036	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404014037	FeS/SAM binding site; other site
544404014038	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
544404014039	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
544404014040	ThiS interaction site; other site
544404014041	putative active site [active]
544404014042	tetramer interface [polypeptide binding]; other site
544404014043	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
544404014044	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
544404014045	ATP binding site [chemical binding]; other site
544404014046	substrate interface [chemical binding]; other site
544404014047	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
544404014048	thiamine phosphate binding site [chemical binding]; other site
544404014049	active site
544404014050	pyrophosphate binding site [ion binding]; other site
544404014051	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
544404014052	ThiC-associated domain; Region: ThiC-associated; pfam13667
544404014053	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
544404014054	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
544404014055	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
544404014056	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
544404014057	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
544404014058	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
544404014059	putative NADH binding site [chemical binding]; other site
544404014060	putative active site [active]
544404014061	nudix motif; other site
544404014062	putative metal binding site [ion binding]; other site
544404014063	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
544404014064	substrate binding site [chemical binding]; other site
544404014065	active site
544404014066	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
544404014067	Active_site [active]
544404014068	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
544404014069	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
544404014070	IHF dimer interface [polypeptide binding]; other site
544404014071	IHF - DNA interface [nucleotide binding]; other site
544404014072	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
544404014073	zinc resistance protein; Provisional; Region: zraP; PRK11546
544404014074	dimer interface [polypeptide binding]; other site
544404014075	sensor protein ZraS; Provisional; Region: PRK10364
544404014076	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404014077	dimer interface [polypeptide binding]; other site
544404014078	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404014079	ATP binding site [chemical binding]; other site
544404014080	Mg2+ binding site [ion binding]; other site
544404014081	G-X-G motif; other site
544404014082	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
544404014083	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404014084	active site
544404014085	phosphorylation site [posttranslational modification]
544404014086	intermolecular recognition site; other site
544404014087	dimerization interface [polypeptide binding]; other site
544404014088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404014089	Walker A motif; other site
544404014090	ATP binding site [chemical binding]; other site
544404014091	Walker B motif; other site
544404014092	arginine finger; other site
544404014093	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
544404014094	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
544404014095	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
544404014096	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
544404014097	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
544404014098	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
544404014099	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
544404014100	purine monophosphate binding site [chemical binding]; other site
544404014101	dimer interface [polypeptide binding]; other site
544404014102	putative catalytic residues [active]
544404014103	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
544404014104	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
544404014105	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404014106	Coenzyme A binding pocket [chemical binding]; other site
544404014107	homoserine O-succinyltransferase; Provisional; Region: PRK05368
544404014108	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
544404014109	proposed active site lysine [active]
544404014110	conserved cys residue [active]
544404014111	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
544404014112	malate synthase A; Region: malate_syn_A; TIGR01344
544404014113	active site
544404014114	isocitrate lyase; Provisional; Region: PRK15063
544404014115	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
544404014116	tetramer interface [polypeptide binding]; other site
544404014117	active site
544404014118	Mg2+/Mn2+ binding site [ion binding]; other site
544404014119	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
544404014120	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
544404014121	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
544404014122	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
544404014123	transcriptional repressor IclR; Provisional; Region: PRK11569
544404014124	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
544404014125	Bacterial transcriptional regulator; Region: IclR; pfam01614
544404014126	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
544404014127	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
544404014128	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
544404014129	substrate binding pocket [chemical binding]; other site
544404014130	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
544404014131	B12 binding site [chemical binding]; other site
544404014132	cobalt ligand [ion binding]; other site
544404014133	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
544404014134	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
544404014135	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
544404014136	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
544404014137	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
544404014138	active site pocket [active]
544404014139	oxyanion hole [active]
544404014140	catalytic triad [active]
544404014141	active site nucleophile [active]
544404014142	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
544404014143	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404014144	putative NAD(P) binding site [chemical binding]; other site
544404014145	catalytic Zn binding site [ion binding]; other site
544404014146	PTS system, mannose/fructose/sorbose family, IID component; Region: EIID-AGA; TIGR00828
544404014147	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
544404014148	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
544404014149	active site
544404014150	phosphorylation site [posttranslational modification]
544404014151	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
544404014152	active pocket/dimerization site; other site
544404014153	active site
544404014154	phosphorylation site [posttranslational modification]
544404014155	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
544404014156	classical (c) SDRs; Region: SDR_c; cd05233
544404014157	NAD(P) binding site [chemical binding]; other site
544404014158	active site
544404014159	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
544404014160	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
544404014161	putative DNA binding site [nucleotide binding]; other site
544404014162	putative Zn2+ binding site [ion binding]; other site
544404014163	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
544404014164	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
544404014165	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
544404014166	RNA binding surface [nucleotide binding]; other site
544404014167	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
544404014168	probable active site [active]
544404014169	hypothetical protein; Provisional; Region: PRK10515
544404014170	aspartate kinase III; Validated; Region: PRK09084
544404014171	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
544404014172	nucleotide binding site [chemical binding]; other site
544404014173	substrate binding site [chemical binding]; other site
544404014174	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
544404014175	lysine allosteric regulatory site; other site
544404014176	dimer interface [polypeptide binding]; other site
544404014177	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
544404014178	dimer interface [polypeptide binding]; other site
544404014179	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
544404014180	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
544404014181	active site
544404014182	dimer interface [polypeptide binding]; other site
544404014183	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
544404014184	dimer interface [polypeptide binding]; other site
544404014185	active site
544404014186	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
544404014187	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
544404014188	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
544404014189	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
544404014190	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
544404014191	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404014192	putative substrate translocation pore; other site
544404014193	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404014194	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
544404014195	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404014196	dimer interface [polypeptide binding]; other site
544404014197	conserved gate region; other site
544404014198	putative PBP binding loops; other site
544404014199	ABC-ATPase subunit interface; other site
544404014200	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404014201	dimer interface [polypeptide binding]; other site
544404014202	conserved gate region; other site
544404014203	putative PBP binding loops; other site
544404014204	ABC-ATPase subunit interface; other site
544404014205	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
544404014206	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
544404014207	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
544404014208	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
544404014209	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
544404014210	Walker A/P-loop; other site
544404014211	ATP binding site [chemical binding]; other site
544404014212	Q-loop/lid; other site
544404014213	ABC transporter signature motif; other site
544404014214	Walker B; other site
544404014215	D-loop; other site
544404014216	H-loop/switch region; other site
544404014217	TOBE domain; Region: TOBE_2; pfam08402
544404014218	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
544404014219	trimer interface; other site
544404014220	sugar binding site [chemical binding]; other site
544404014221	maltose regulon periplasmic protein; Provisional; Region: PRK10564
544404014222	hypothetical protein; Validated; Region: PRK09718
544404014223	SopA-like central domain; Region: SopA; pfam13981
544404014224	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
544404014225	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
544404014226	UbiA prenyltransferase family; Region: UbiA; pfam01040
544404014227	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
544404014228	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
544404014229	putative acyl-acceptor binding pocket; other site
544404014230	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
544404014231	LexA repressor; Validated; Region: PRK00215
544404014232	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
544404014233	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
544404014234	Catalytic site [active]
544404014235	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
544404014236	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
544404014237	hypothetical protein; Provisional; Region: PRK10428
544404014238	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
544404014239	metal binding site 2 [ion binding]; metal-binding site
544404014240	putative DNA binding helix; other site
544404014241	metal binding site 1 [ion binding]; metal-binding site
544404014242	dimer interface [polypeptide binding]; other site
544404014243	structural Zn2+ binding site [ion binding]; other site
544404014244	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
544404014245	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
544404014246	Pyocin activator protein PrtN; Region: PyocinActivator; pfam11112
544404014247	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
544404014248	active site
544404014249	substrate binding site [chemical binding]; other site
544404014250	catalytic site [active]
544404014251	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
544404014252	Uncharacterized conserved protein (DUF2303); Region: DUF2303; cl02338
544404014253	Fibronectin type III protein; Region: DUF3672; pfam12421
544404014254	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
544404014255	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
544404014256	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
544404014257	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404014258	Putative prophage tail fibre C-terminus; Region: Phage_fiber_C; pfam06820
544404014259	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404014260	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404014261	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
544404014262	DinI-like family; Region: DinI; pfam06183
544404014263	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404014264	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404014265	active site
544404014266	DNA binding site [nucleotide binding]
544404014267	Int/Topo IB signature motif; other site
544404014268	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
544404014269	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
544404014270	FMN binding site [chemical binding]; other site
544404014271	active site
544404014272	catalytic residues [active]
544404014273	substrate binding site [chemical binding]; other site
544404014274	phage shock protein G; Reviewed; Region: pspG; PRK09459
544404014275	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
544404014276	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
544404014277	NADP binding site [chemical binding]; other site
544404014278	dimer interface [polypeptide binding]; other site
544404014279	replicative DNA helicase; Provisional; Region: PRK08006
544404014280	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
544404014281	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
544404014282	Walker A motif; other site
544404014283	ATP binding site [chemical binding]; other site
544404014284	Walker B motif; other site
544404014285	DNA binding loops [nucleotide binding]
544404014286	alanine racemase; Reviewed; Region: alr; PRK00053
544404014287	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
544404014288	active site
544404014289	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
544404014290	substrate binding site [chemical binding]; other site
544404014291	catalytic residues [active]
544404014292	dimer interface [polypeptide binding]; other site
544404014293	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
544404014294	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404014295	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404014296	homodimer interface [polypeptide binding]; other site
544404014297	catalytic residue [active]
544404014298	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404014299	active site
544404014300	motif I; other site
544404014301	motif II; other site
544404014302	secondary thiamine-phosphate synthase enzyme; Region: TIGR00149_YjbQ
544404014303	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
544404014304	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
544404014305	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
544404014306	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
544404014307	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
544404014308	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
544404014309	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
544404014310	dimer interface [polypeptide binding]; other site
544404014311	ssDNA binding site [nucleotide binding]; other site
544404014312	tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404014313	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
544404014314	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
544404014315	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
544404014316	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
544404014317	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
544404014318	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404014319	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
544404014320	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
544404014321	DNA binding residues [nucleotide binding]
544404014322	dimer interface [polypeptide binding]; other site
544404014323	[2Fe-2S] cluster binding site [ion binding]; other site
544404014324	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
544404014325	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
544404014326	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
544404014327	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
544404014328	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404014329	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404014330	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
544404014331	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
544404014332	Na binding site [ion binding]; other site
544404014333	Predicted membrane protein [Function unknown]; Region: COG3162
544404014334	acetyl-CoA synthetase; Provisional; Region: PRK00174
544404014335	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
544404014336	active site
544404014337	CoA binding site [chemical binding]; other site
544404014338	acyl-activating enzyme (AAE) consensus motif; other site
544404014339	AMP binding site [chemical binding]; other site
544404014340	acetate binding site [chemical binding]; other site
544404014341	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
544404014342	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
544404014343	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
544404014344	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
544404014345	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
544404014346	heme lyase subunit NrfE; Provisional; Region: PRK10369
544404014347	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
544404014348	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
544404014349	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
544404014350	binding surface
544404014351	TPR motif; other site
544404014352	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
544404014353	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
544404014354	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
544404014355	Sel1-like repeats; Region: SEL1; smart00671
544404014356	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
544404014357	molybdopterin cofactor binding site; other site
544404014358	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
544404014359	molybdopterin cofactor binding site; other site
544404014360	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
544404014361	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
544404014362	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
544404014363	multidrug resistance protein MdtN; Provisional; Region: PRK10476
544404014364	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
544404014365	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404014366	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
544404014367	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
544404014368	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
544404014369	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404014370	active site
544404014371	phosphorylation site [posttranslational modification]
544404014372	intermolecular recognition site; other site
544404014373	dimerization interface [polypeptide binding]; other site
544404014374	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404014375	DNA binding site [nucleotide binding]
544404014376	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
544404014377	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
544404014378	substrate binding site [chemical binding]; other site
544404014379	ATP binding site [chemical binding]; other site
544404014380	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
544404014381	intersubunit interface [polypeptide binding]; other site
544404014382	active site
544404014383	zinc binding site [ion binding]; other site
544404014384	Na+ binding site [ion binding]; other site
544404014385	Protein of unknown function (DUF1498); Region: DUF1498; pfam07385
544404014386	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
544404014387	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
544404014388	putative ligand binding site [chemical binding]; other site
544404014389	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404014390	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404014391	TM-ABC transporter signature motif; other site
544404014392	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
544404014393	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404014394	Walker A/P-loop; other site
544404014395	ATP binding site [chemical binding]; other site
544404014396	Q-loop/lid; other site
544404014397	ABC transporter signature motif; other site
544404014398	Walker B; other site
544404014399	D-loop; other site
544404014400	H-loop/switch region; other site
544404014401	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
544404014402	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
544404014403	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404014404	dimerization interface [polypeptide binding]; other site
544404014405	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404014406	dimer interface [polypeptide binding]; other site
544404014407	phosphorylation site [posttranslational modification]
544404014408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404014409	ATP binding site [chemical binding]; other site
544404014410	Mg2+ binding site [ion binding]; other site
544404014411	G-X-G motif; other site
544404014412	Response regulator receiver domain; Region: Response_reg; pfam00072
544404014413	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404014414	active site
544404014415	phosphorylation site [posttranslational modification]
544404014416	intermolecular recognition site; other site
544404014417	dimerization interface [polypeptide binding]; other site
544404014418	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
544404014419	putative hydrolase; Provisional; Region: PRK02113
544404014420	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404014421	Coenzyme A binding pocket [chemical binding]; other site
544404014422	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
544404014423	AAA domain; Region: AAA_18; pfam13238
544404014424	active site
544404014425	Metal-dependent hydrolase involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: COG3454
544404014426	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
544404014427	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
544404014428	active site
544404014429	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
544404014430	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
544404014431	Walker A/P-loop; other site
544404014432	ATP binding site [chemical binding]; other site
544404014433	Q-loop/lid; other site
544404014434	ABC transporter signature motif; other site
544404014435	Walker B; other site
544404014436	D-loop; other site
544404014437	H-loop/switch region; other site
544404014438	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
544404014439	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
544404014440	Walker A/P-loop; other site
544404014441	ATP binding site [chemical binding]; other site
544404014442	Q-loop/lid; other site
544404014443	ABC transporter signature motif; other site
544404014444	Walker B; other site
544404014445	D-loop; other site
544404014446	H-loop/switch region; other site
544404014447	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
544404014448	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
544404014449	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
544404014450	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
544404014451	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
544404014452	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
544404014453	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404014454	DNA-binding site [nucleotide binding]; DNA binding site
544404014455	UTRA domain; Region: UTRA; pfam07702
544404014456	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
544404014457	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
544404014458	dimer interface [polypeptide binding]; other site
544404014459	conserved gate region; other site
544404014460	putative PBP binding loops; other site
544404014461	ABC-ATPase subunit interface; other site
544404014462	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
544404014463	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
544404014464	substrate binding pocket [chemical binding]; other site
544404014465	membrane-bound complex binding site; other site
544404014466	hinge residues; other site
544404014467	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
544404014468	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
544404014469	Walker A/P-loop; other site
544404014470	ATP binding site [chemical binding]; other site
544404014471	Q-loop/lid; other site
544404014472	ABC transporter signature motif; other site
544404014473	Walker B; other site
544404014474	D-loop; other site
544404014475	H-loop/switch region; other site
544404014476	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
544404014477	dimer interface [polypeptide binding]; other site
544404014478	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
544404014479	hypothetical protein; Provisional; Region: PRK10220
544404014480	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
544404014481	PhnA protein; Region: PhnA; pfam03831
544404014482	hypothetical protein; Provisional; Region: PRK09866
544404014483	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
544404014484	G1 box; other site
544404014485	GTP/Mg2+ binding site [chemical binding]; other site
544404014486	G2 box; other site
544404014487	Switch I region; other site
544404014488	G3 box; other site
544404014489	Switch II region; other site
544404014490	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
544404014491	G2 box; other site
544404014492	Switch I region; other site
544404014493	G3 box; other site
544404014494	Switch II region; other site
544404014495	G4 box; other site
544404014496	G5 box; other site
544404014497	YjcZ-like protein; Region: YjcZ; pfam13990
544404014498	proline/glycine betaine transporter; Provisional; Region: PRK10642
544404014499	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404014500	putative substrate translocation pore; other site
544404014501	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
544404014502	sensor protein BasS/PmrB; Provisional; Region: PRK10755
544404014503	HAMP domain; Region: HAMP; pfam00672
544404014504	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404014505	dimer interface [polypeptide binding]; other site
544404014506	phosphorylation site [posttranslational modification]
544404014507	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404014508	ATP binding site [chemical binding]; other site
544404014509	Mg2+ binding site [ion binding]; other site
544404014510	G-X-G motif; other site
544404014511	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
544404014512	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404014513	active site
544404014514	phosphorylation site [posttranslational modification]
544404014515	intermolecular recognition site; other site
544404014516	dimerization interface [polypeptide binding]; other site
544404014517	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404014518	DNA binding site [nucleotide binding]
544404014519	putative metal dependent hydrolase; Provisional; Region: PRK11598
544404014520	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
544404014521	Sulfatase; Region: Sulfatase; pfam00884
544404014522	arginine:agmatin antiporter; Provisional; Region: PRK10644
544404014523	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
544404014524	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404014525	arginine decarboxylase; Provisional; Region: PRK15029
544404014526	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
544404014527	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
544404014528	homodimer interface [polypeptide binding]; other site
544404014529	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404014530	catalytic residue [active]
544404014531	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
544404014532	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
544404014533	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404014534	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404014535	alpha-galactosidase; Provisional; Region: PRK15076
544404014536	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
544404014537	NAD binding site [chemical binding]; other site
544404014538	sugar binding site [chemical binding]; other site
544404014539	divalent metal binding site [ion binding]; other site
544404014540	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404014541	dimer interface [polypeptide binding]; other site
544404014542	melibiose:sodium symporter; Provisional; Region: PRK10429
544404014543	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
544404014544	hypothetical protein; Provisional; Region: PRK09867
544404014545	fumarate hydratase; Provisional; Region: PRK15389
544404014546	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
544404014547	Fumarase C-terminus; Region: Fumerase_C; pfam05683
544404014548	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
544404014549	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
544404014550	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
544404014551	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404014552	active site
544404014553	phosphorylation site [posttranslational modification]
544404014554	intermolecular recognition site; other site
544404014555	dimerization interface [polypeptide binding]; other site
544404014556	Transcriptional regulator; Region: CitT; pfam12431
544404014557	sensory histidine kinase DcuS; Provisional; Region: PRK11086
544404014558	PAS domain; Region: PAS; smart00091
544404014559	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404014560	ATP binding site [chemical binding]; other site
544404014561	Mg2+ binding site [ion binding]; other site
544404014562	G-X-G motif; other site
544404014563	Uncharacterized conserved protein [Function unknown]; Region: COG3592
544404014564	Predicted acetyltransferase [General function prediction only]; Region: COG2388
544404014565	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
544404014566	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
544404014567	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
544404014568	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
544404014569	dimer interface [polypeptide binding]; other site
544404014570	putative anticodon binding site; other site
544404014571	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
544404014572	motif 1; other site
544404014573	active site
544404014574	motif 2; other site
544404014575	motif 3; other site
544404014576	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
544404014577	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404014578	putative substrate translocation pore; other site
544404014579	POT family; Region: PTR2; pfam00854
544404014580	lysine decarboxylase CadA; Provisional; Region: PRK15400
544404014581	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
544404014582	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
544404014583	homodimer interface [polypeptide binding]; other site
544404014584	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404014585	catalytic residue [active]
544404014586	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
544404014587	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
544404014588	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
544404014589	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404014590	DNA binding site [nucleotide binding]
544404014591	putative transcriptional regulator; Provisional; Region: PRK11640
544404014592	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404014593	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
544404014594	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
544404014595	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
544404014596	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
544404014597	DsbD alpha interface [polypeptide binding]; other site
544404014598	catalytic residues [active]
544404014599	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
544404014600	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
544404014601	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
544404014602	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
544404014603	Aspartase; Region: Aspartase; cd01357
544404014604	active sites [active]
544404014605	tetramer interface [polypeptide binding]; other site
544404014606	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
544404014607	putative transporter; Provisional; Region: PRK11021
544404014608	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
544404014609	oligomerisation interface [polypeptide binding]; other site
544404014610	mobile loop; other site
544404014611	roof hairpin; other site
544404014612	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
544404014613	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
544404014614	ring oligomerisation interface [polypeptide binding]; other site
544404014615	ATP/Mg binding site [chemical binding]; other site
544404014616	stacking interactions; other site
544404014617	hinge regions; other site
544404014618	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
544404014619	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
544404014620	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404014621	FeS/SAM binding site; other site
544404014622	elongation factor P; Validated; Region: PRK00529
544404014623	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
544404014624	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
544404014625	RNA binding site [nucleotide binding]; other site
544404014626	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
544404014627	RNA binding site [nucleotide binding]; other site
544404014628	entericidin A; Provisional; Region: PRK09810
544404014629	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
544404014630	multidrug efflux system protein; Provisional; Region: PRK11431
544404014631	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
544404014632	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
544404014633	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
544404014634	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
544404014635	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
544404014636	Iron-sulfur protein interface; other site
544404014637	proximal quinone binding site [chemical binding]; other site
544404014638	C-subunit interface; other site
544404014639	distal quinone binding site; other site
544404014640	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
544404014641	D-subunit interface [polypeptide binding]; other site
544404014642	Iron-sulfur protein interface; other site
544404014643	proximal quinone binding site [chemical binding]; other site
544404014644	distal quinone binding site [chemical binding]; other site
544404014645	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
544404014646	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
544404014647	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
544404014648	L-aspartate oxidase; Provisional; Region: PRK06175
544404014649	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
544404014650	poxB regulator PoxA; Provisional; Region: PRK09350
544404014651	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
544404014652	motif 1; other site
544404014653	dimer interface [polypeptide binding]; other site
544404014654	active site
544404014655	motif 2; other site
544404014656	motif 3; other site
544404014657	inner membrane transporter YjeM; Provisional; Region: PRK15238
544404014658	putative mechanosensitive channel protein; Provisional; Region: PRK10929
544404014659	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
544404014660	DNA-binding site [nucleotide binding]; DNA binding site
544404014661	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
544404014662	Mechanosensitive ion channel; Region: MS_channel; pfam00924
544404014663	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
544404014664	GTPase RsgA; Reviewed; Region: PRK12288
544404014665	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
544404014666	RNA binding site [nucleotide binding]; other site
544404014667	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
544404014668	GTPase/Zn-binding domain interface [polypeptide binding]; other site
544404014669	GTP/Mg2+ binding site [chemical binding]; other site
544404014670	G4 box; other site
544404014671	G5 box; other site
544404014672	G1 box; other site
544404014673	Switch I region; other site
544404014674	G2 box; other site
544404014675	G3 box; other site
544404014676	Switch II region; other site
544404014677	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
544404014678	catalytic site [active]
544404014679	putative active site [active]
544404014680	putative substrate binding site [chemical binding]; other site
544404014681	dimer interface [polypeptide binding]; other site
544404014682	epoxyqueuosine reductase; Region: TIGR00276
544404014683	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
544404014684	putative carbohydrate kinase; Provisional; Region: PRK10565
544404014685	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
544404014686	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
544404014687	putative substrate binding site [chemical binding]; other site
544404014688	putative ATP binding site [chemical binding]; other site
544404014689	ADP-binding protein; Provisional; Region: PRK10646
544404014690	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
544404014691	AMIN domain; Region: AMIN; pfam11741
544404014692	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
544404014693	active site
544404014694	metal binding site [ion binding]; metal-binding site
544404014695	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
544404014696	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404014697	ATP binding site [chemical binding]; other site
544404014698	Mg2+ binding site [ion binding]; other site
544404014699	G-X-G motif; other site
544404014700	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
544404014701	ATP binding site [chemical binding]; other site
544404014702	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
544404014703	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
544404014704	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
544404014705	bacterial Hfq-like; Region: Hfq; cd01716
544404014706	hexamer interface [polypeptide binding]; other site
544404014707	Sm1 motif; other site
544404014708	RNA binding site [nucleotide binding]; other site
544404014709	Sm2 motif; other site
544404014710	GTPase HflX; Provisional; Region: PRK11058
544404014711	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
544404014712	HflX GTPase family; Region: HflX; cd01878
544404014713	G1 box; other site
544404014714	GTP/Mg2+ binding site [chemical binding]; other site
544404014715	Switch I region; other site
544404014716	G2 box; other site
544404014717	G3 box; other site
544404014718	Switch II region; other site
544404014719	G4 box; other site
544404014720	G5 box; other site
544404014721	FtsH protease regulator HflK; Provisional; Region: PRK10930
544404014722	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
544404014723	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
544404014724	FtsH protease regulator HflC; Provisional; Region: PRK11029
544404014725	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
544404014726	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
544404014727	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
544404014728	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
544404014729	GDP-binding site [chemical binding]; other site
544404014730	ACT binding site; other site
544404014731	IMP binding site; other site
544404014732	Predicted transcriptional regulator [Transcription]; Region: COG1959
544404014733	transcriptional repressor NsrR; Provisional; Region: PRK11014
544404014734	exoribonuclease R; Provisional; Region: PRK11642
544404014735	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
544404014736	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
544404014737	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
544404014738	RNB domain; Region: RNB; pfam00773
544404014739	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
544404014740	RNA binding site [nucleotide binding]; other site
544404014741	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
544404014742	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
544404014743	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
544404014744	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
544404014745	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
544404014746	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
544404014747	Predicted membrane protein [Function unknown]; Region: COG3766
544404014748	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
544404014749	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
544404014750	Predicted integral membrane protein [Function unknown]; Region: COG5463
544404014751	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
544404014752	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
544404014753	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
544404014754	FAD binding site [chemical binding]; other site
544404014755	substrate binding site [chemical binding]; other site
544404014756	catalytic residues [active]
544404014757	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404014758	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
544404014759	esterase; Provisional; Region: PRK10566
544404014760	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
544404014761	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
544404014762	transcriptional repressor UlaR; Provisional; Region: PRK13509
544404014763	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
544404014764	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
544404014765	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
544404014766	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
544404014767	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
544404014768	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
544404014769	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
544404014770	active site
544404014771	P-loop; other site
544404014772	phosphorylation site [posttranslational modification]
544404014773	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
544404014774	active site
544404014775	phosphorylation site [posttranslational modification]
544404014776	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
544404014777	active site
544404014778	dimer interface [polypeptide binding]; other site
544404014779	magnesium binding site [ion binding]; other site
544404014780	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
544404014781	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
544404014782	AP (apurinic/apyrimidinic) site pocket; other site
544404014783	DNA interaction; other site
544404014784	Metal-binding active site; metal-binding site
544404014785	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
544404014786	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
544404014787	intersubunit interface [polypeptide binding]; other site
544404014788	active site
544404014789	Zn2+ binding site [ion binding]; other site
544404014790	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
544404014791	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
544404014792	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
544404014793	dimer interface [polypeptide binding]; other site
544404014794	ssDNA binding site [nucleotide binding]; other site
544404014795	tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404014796	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
544404014797	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
544404014798	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
544404014799	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
544404014800	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
544404014801	Transposase IS200 like; Region: Y1_Tnp; pfam01797
544404014802	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
544404014803	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
544404014804	Probable transposase; Region: OrfB_IS605; pfam01385
544404014805	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
544404014806	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
544404014807	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
544404014808	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
544404014809	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
544404014810	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
544404014811	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
544404014812	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
544404014813	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
544404014814	Hemerythrin-like domain; Region: Hr-like; cd12108
544404014815	Fe binding site [ion binding]; other site
544404014816	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
544404014817	EamA-like transporter family; Region: EamA; pfam00892
544404014818	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
544404014819	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
544404014820	NADP binding site [chemical binding]; other site
544404014821	Predicted transcriptional regulators [Transcription]; Region: COG1733
544404014822	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
544404014823	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
544404014824	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
544404014825	active site
544404014826	metal binding site [ion binding]; metal-binding site
544404014827	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
544404014828	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
544404014829	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
544404014830	active site
544404014831	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
544404014832	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
544404014833	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
544404014834	Domain of unknown function DUF21; Region: DUF21; pfam01595
544404014835	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
544404014836	Transporter associated domain; Region: CorC_HlyC; smart01091
544404014837	methionine sulfoxide reductase A; Provisional; Region: PRK00058
544404014838	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
544404014839	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
544404014840	Surface antigen; Region: Bac_surface_Ag; pfam01103
544404014841	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
544404014842	Family of unknown function (DUF490); Region: DUF490; pfam04357
544404014843	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
544404014844	putative active site pocket [active]
544404014845	dimerization interface [polypeptide binding]; other site
544404014846	putative catalytic residue [active]
544404014847	antitoxin ChpS; Provisional; Region: PRK11347
544404014848	toxin ChpB; Provisional; Region: PRK09812
544404014849	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
544404014850	dimer interface [polypeptide binding]; other site
544404014851	substrate binding site [chemical binding]; other site
544404014852	metal binding sites [ion binding]; metal-binding site
544404014853	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
544404014854	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
544404014855	putative ligand binding site [chemical binding]; other site
544404014856	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
544404014857	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
544404014858	Walker A/P-loop; other site
544404014859	ATP binding site [chemical binding]; other site
544404014860	Q-loop/lid; other site
544404014861	ABC transporter signature motif; other site
544404014862	Walker B; other site
544404014863	D-loop; other site
544404014864	H-loop/switch region; other site
544404014865	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404014866	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404014867	TM-ABC transporter signature motif; other site
544404014868	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
544404014869	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
544404014870	TM-ABC transporter signature motif; other site
544404014871	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
544404014872	AMP binding site [chemical binding]; other site
544404014873	metal binding site [ion binding]; metal-binding site
544404014874	active site
544404014875	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
544404014876	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
544404014877	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
544404014878	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
544404014879	hypothetical protein; Provisional; Region: PRK05255
544404014880	peptidase PmbA; Provisional; Region: PRK11040
544404014881	cytochrome b562; Provisional; Region: PRK15058
544404014882	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
544404014883	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404014884	FeS/SAM binding site; other site
544404014885	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
544404014886	ATP cone domain; Region: ATP-cone; pfam03477
544404014887	Class III ribonucleotide reductase; Region: RNR_III; cd01675
544404014888	effector binding site; other site
544404014889	active site
544404014890	Zn binding site [ion binding]; other site
544404014891	glycine loop; other site
544404014892	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
544404014893	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
544404014894	Ca binding site [ion binding]; other site
544404014895	active site
544404014896	catalytic site [active]
544404014897	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
544404014898	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
544404014899	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
544404014900	active site turn [active]
544404014901	phosphorylation site [posttranslational modification]
544404014902	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
544404014903	trehalose repressor; Provisional; Region: treR; PRK09492
544404014904	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
544404014905	DNA binding site [nucleotide binding]
544404014906	domain linker motif; other site
544404014907	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
544404014908	dimerization interface [polypeptide binding]; other site
544404014909	ligand binding site [chemical binding]; other site
544404014910	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
544404014911	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
544404014912	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
544404014913	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
544404014914	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404014915	motif II; other site
544404014916	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
544404014917	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
544404014918	homotrimer interaction site [polypeptide binding]; other site
544404014919	putative active site [active]
544404014920	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
544404014921	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
544404014922	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
544404014923	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
544404014924	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
544404014925	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
544404014926	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
544404014927	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
544404014928	homotrimer interaction site [polypeptide binding]; other site
544404014929	putative active site [active]
544404014930	oxidoreductase; Provisional; Region: PRK12742
544404014931	classical (c) SDRs; Region: SDR_c; cd05233
544404014932	NAD(P) binding site [chemical binding]; other site
544404014933	active site
544404014934	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
544404014935	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
544404014936	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
544404014937	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
544404014938	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
544404014939	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
544404014940	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
544404014941	RNase E inhibitor protein; Provisional; Region: PRK11191
544404014942	Predicted membrane protein [Function unknown]; Region: COG4269
544404014943	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
544404014944	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
544404014945	HIGH motif; other site
544404014946	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
544404014947	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
544404014948	active site
544404014949	KMSKS motif; other site
544404014950	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
544404014951	tRNA binding surface [nucleotide binding]; other site
544404014952	anticodon binding site; other site
544404014953	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
544404014954	DNA polymerase III subunit chi; Validated; Region: PRK05728
544404014955	multifunctional aminopeptidase A; Provisional; Region: PRK00913
544404014956	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
544404014957	interface (dimer of trimers) [polypeptide binding]; other site
544404014958	Substrate-binding/catalytic site; other site
544404014959	Zn-binding sites [ion binding]; other site
544404014960	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
544404014961	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
544404014962	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
544404014963	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
544404014964	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
544404014965	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
544404014966	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
544404014967	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
544404014968	putative NAD(P) binding site [chemical binding]; other site
544404014969	putative substrate binding site [chemical binding]; other site
544404014970	catalytic Zn binding site [ion binding]; other site
544404014971	structural Zn binding site [ion binding]; other site
544404014972	dimer interface [polypeptide binding]; other site
544404014973	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
544404014974	INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184
544404014975	Int/Topo IB signature motif; other site
544404014976	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
544404014977	NIPSNAP; Region: NIPSNAP; pfam07978
544404014978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4333
544404014979	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
544404014980	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
544404014981	catalytic residues [active]
544404014982	catalytic nucleophile [active]
544404014983	Presynaptic Site I dimer interface [polypeptide binding]; other site
544404014984	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
544404014985	Synaptic Flat tetramer interface [polypeptide binding]; other site
544404014986	Synaptic Site I dimer interface [polypeptide binding]; other site
544404014987	DNA binding site [nucleotide binding]
544404014988	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
544404014989	DNA-binding interface [nucleotide binding]; DNA binding site
544404014990	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
544404014991	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404014992	non-specific DNA binding site [nucleotide binding]; other site
544404014993	salt bridge; other site
544404014994	sequence-specific DNA binding site [nucleotide binding]; other site
544404014995	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
544404014996	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
544404014997	HNH endonuclease; Region: HNH_2; pfam13391
544404014998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3055
544404014999	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
544404015000	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
544404015001	active site
544404015002	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
544404015003	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
544404015004	ligand binding site [chemical binding]; other site
544404015005	Protein of unknown function (DUF3375); Region: DUF3375; pfam11855
544404015006	Capsid triplex subunit 2; Provisional; Region: PHA03259
544404015007	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
544404015008	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404015009	ATP binding site [chemical binding]; other site
544404015010	putative Mg++ binding site [ion binding]; other site
544404015011	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404015012	nucleotide binding region [chemical binding]; other site
544404015013	ATP-binding site [chemical binding]; other site
544404015014	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
544404015015	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
544404015016	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404015017	ATP binding site [chemical binding]; other site
544404015018	putative Mg++ binding site [ion binding]; other site
544404015019	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404015020	nucleotide binding region [chemical binding]; other site
544404015021	ATP-binding site [chemical binding]; other site
544404015022	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
544404015023	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
544404015024	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404015025	ATP binding site [chemical binding]; other site
544404015026	putative Mg++ binding site [ion binding]; other site
544404015027	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
544404015028	ATP-binding site [chemical binding]; other site
544404015029	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
544404015030	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
544404015031	Part of AAA domain; Region: AAA_19; pfam13245
544404015032	Family description; Region: UvrD_C_2; pfam13538
544404015033	Domain of unknown function (DUF303); Region: DUF303; pfam03629
544404015034	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
544404015035	Kelch motif; Region: Kelch_1; pfam01344
544404015036	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
544404015037	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
544404015038	Int/Topo IB signature motif; other site
544404015039	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
544404015040	Int/Topo IB signature motif; other site
544404015041	Fimbrial protein; Region: Fimbrial; cl01416
544404015042	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404015043	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
544404015044	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
544404015045	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
544404015046	outer membrane usher protein; Provisional; Region: PRK15193
544404015047	PapC N-terminal domain; Region: PapC_N; pfam13954
544404015048	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
544404015049	PapC C-terminal domain; Region: PapC_C; pfam13953
544404015050	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404015051	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
544404015052	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
544404015053	mannosyl binding site [chemical binding]; other site
544404015054	Fimbrial protein; Region: Fimbrial; pfam00419
544404015055	fructuronate transporter; Provisional; Region: PRK10034
544404015056	gluconate transporter; Region: gntP; TIGR00791
544404015057	mannonate dehydratase; Region: uxuA; TIGR00695
544404015058	mannonate dehydratase; Provisional; Region: PRK03906
544404015059	D-mannonate oxidoreductase; Provisional; Region: PRK15037
544404015060	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
544404015061	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
544404015062	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
544404015063	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404015064	DNA-binding site [nucleotide binding]; DNA binding site
544404015065	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
544404015066	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
544404015067	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
544404015068	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
544404015069	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
544404015070	dimer interface [polypeptide binding]; other site
544404015071	active site
544404015072	hypothetical protein; Provisional; Region: PRK10519
544404015073	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
544404015074	Nucleoside recognition; Region: Gate; pfam07670
544404015075	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
544404015076	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
544404015077	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015078	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015079	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015080	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015081	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015082	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015083	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015084	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
544404015085	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
544404015086	Major Facilitator Superfamily; Region: MFS_1; pfam07690
544404015087	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404015088	putative substrate translocation pore; other site
544404015089	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
544404015090	SdiA-regulated; Region: SdiA-regulated; cd09971
544404015091	putative active site [active]
544404015092	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
544404015093	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404015094	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404015095	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404015096	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404015097	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
544404015098	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
544404015099	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
544404015100	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
544404015101	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
544404015102	Predicted membrane protein [Function unknown]; Region: COG2733
544404015103	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
544404015104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404015105	putative substrate translocation pore; other site
544404015106	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
544404015107	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404015108	DNA-binding site [nucleotide binding]; DNA binding site
544404015109	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
544404015110	pyridoxal 5'-phosphate binding site [chemical binding]; other site
544404015111	homodimer interface [polypeptide binding]; other site
544404015112	catalytic residue [active]
544404015113	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
544404015114	endoribonuclease SymE; Provisional; Region: PRK13605
544404015115	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
544404015116	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
544404015117	HsdM N-terminal domain; Region: HsdM_N; pfam12161
544404015118	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
544404015119	Methyltransferase domain; Region: Methyltransf_26; pfam13659
544404015120	S-adenosylmethionine binding site [chemical binding]; other site
544404015121	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
544404015122	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
544404015123	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
544404015124	ATP binding site [chemical binding]; other site
544404015125	putative Mg++ binding site [ion binding]; other site
544404015126	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
544404015127	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
544404015128	P-loop, Walker A motif; other site
544404015129	Base recognition motif; other site
544404015130	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
544404015131	Uncharacterized small protein [Function unknown]; Region: COG2879
544404015132	carbon starvation protein A; Provisional; Region: PRK15015
544404015133	Carbon starvation protein CstA; Region: CstA; pfam02554
544404015134	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
544404015135	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
544404015136	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
544404015137	dimer interface [polypeptide binding]; other site
544404015138	ligand binding site [chemical binding]; other site
544404015139	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404015140	dimerization interface [polypeptide binding]; other site
544404015141	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
544404015142	dimer interface [polypeptide binding]; other site
544404015143	putative CheW interface [polypeptide binding]; other site
544404015144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
544404015145	D-galactonate transporter; Region: 2A0114; TIGR00893
544404015146	putative substrate translocation pore; other site
544404015147	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
544404015148	DNA-binding site [nucleotide binding]; DNA binding site
544404015149	Transcriptional regulators [Transcription]; Region: GntR; COG1802
544404015150	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
544404015151	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
544404015152	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
544404015153	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
544404015154	putative NAD(P) binding site [chemical binding]; other site
544404015155	catalytic Zn binding site [ion binding]; other site
544404015156	structural Zn binding site [ion binding]; other site
544404015157	phosphoglycerol transferase I; Provisional; Region: PRK03776
544404015158	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
544404015159	hypothetical protein; Provisional; Region: PRK11667
544404015160	DNA replication protein DnaC; Validated; Region: PRK07952
544404015161	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
544404015162	Walker A motif; other site
544404015163	ATP binding site [chemical binding]; other site
544404015164	Walker B motif; other site
544404015165	primosomal protein DnaI; Provisional; Region: PRK02854
544404015166	hypothetical protein; Provisional; Region: PRK09917
544404015167	Uncharacterized conserved protein [Function unknown]; Region: COG2966
544404015168	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
544404015169	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
544404015170	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404015171	DNA binding residues [nucleotide binding]
544404015172	dimerization interface [polypeptide binding]; other site
544404015173	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
544404015174	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
544404015175	DNA binding residues [nucleotide binding]
544404015176	dimerization interface [polypeptide binding]; other site
544404015177	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
544404015178	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
544404015179	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
544404015180	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
544404015181	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
544404015182	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
544404015183	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404015184	S-adenosylmethionine binding site [chemical binding]; other site
544404015185	DNA polymerase III subunit psi; Validated; Region: PRK06856
544404015186	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
544404015187	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
544404015188	Coenzyme A binding pocket [chemical binding]; other site
544404015189	dUMP phosphatase; Provisional; Region: PRK09449
544404015190	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404015191	motif II; other site
544404015192	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
544404015193	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
544404015194	G1 box; other site
544404015195	putative GEF interaction site [polypeptide binding]; other site
544404015196	GTP/Mg2+ binding site [chemical binding]; other site
544404015197	Switch I region; other site
544404015198	G2 box; other site
544404015199	G3 box; other site
544404015200	Switch II region; other site
544404015201	G4 box; other site
544404015202	G5 box; other site
544404015203	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
544404015204	periplasmic protein; Provisional; Region: PRK10568
544404015205	BON domain; Region: BON; pfam04972
544404015206	BON domain; Region: BON; pfam04972
544404015207	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
544404015208	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
544404015209	active site
544404015210	nucleophile elbow; other site
544404015211	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
544404015212	active site
544404015213	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
544404015214	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
544404015215	FeS/SAM binding site; other site
544404015216	hypothetical protein; Provisional; Region: PRK10977
544404015217	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
544404015218	intersubunit interface [polypeptide binding]; other site
544404015219	active site
544404015220	catalytic residue [active]
544404015221	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
544404015222	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
544404015223	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
544404015224	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
544404015225	phosphopentomutase; Provisional; Region: PRK05362
544404015226	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
544404015227	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
544404015228	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
544404015229	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404015230	non-specific DNA binding site [nucleotide binding]; other site
544404015231	salt bridge; other site
544404015232	sequence-specific DNA binding site [nucleotide binding]; other site
544404015233	unknown domain/lipoate-protein ligase A fusion protein; Provisional; Region: PRK14061
544404015234	hypothetical protein; Provisional; Region: PRK11246
544404015235	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
544404015236	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
544404015237	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
544404015238	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
544404015239	motif II; other site
544404015240	DNA repair protein RadA; Region: sms; TIGR00416
544404015241	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
544404015242	Walker A motif/ATP binding site; other site
544404015243	ATP binding site [chemical binding]; other site
544404015244	Walker B motif; other site
544404015245	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
544404015246	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
544404015247	non-specific DNA binding site [nucleotide binding]; other site
544404015248	salt bridge; other site
544404015249	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
544404015250	sequence-specific DNA binding site [nucleotide binding]; other site
544404015251	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
544404015252	active site
544404015253	(T/H)XGH motif; other site
544404015254	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
544404015255	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
544404015256	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
544404015257	Walker A/P-loop; other site
544404015258	ATP binding site [chemical binding]; other site
544404015259	Q-loop/lid; other site
544404015260	ABC transporter signature motif; other site
544404015261	Walker B; other site
544404015262	D-loop; other site
544404015263	H-loop/switch region; other site
544404015264	ABC transporter; Region: ABC_tran_2; pfam12848
544404015265	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
544404015266	lytic murein transglycosylase; Provisional; Region: PRK11619
544404015267	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
544404015268	N-acetyl-D-glucosamine binding site [chemical binding]; other site
544404015269	catalytic residue [active]
544404015270	Trp operon repressor; Provisional; Region: PRK01381
544404015271	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
544404015272	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
544404015273	catalytic core [active]
544404015274	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
544404015275	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
544404015276	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
544404015277	hypothetical protein; Provisional; Region: PRK10756
544404015278	CreA protein; Region: CreA; pfam05981
544404015279	DNA-binding response regulator CreB; Provisional; Region: PRK11083
544404015280	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404015281	active site
544404015282	phosphorylation site [posttranslational modification]
544404015283	intermolecular recognition site; other site
544404015284	dimerization interface [polypeptide binding]; other site
544404015285	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404015286	DNA binding site [nucleotide binding]
544404015287	sensory histidine kinase CreC; Provisional; Region: PRK11100
544404015288	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
544404015289	dimerization interface [polypeptide binding]; other site
544404015290	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
544404015291	dimer interface [polypeptide binding]; other site
544404015292	phosphorylation site [posttranslational modification]
544404015293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
544404015294	ATP binding site [chemical binding]; other site
544404015295	Mg2+ binding site [ion binding]; other site
544404015296	G-X-G motif; other site
544404015297	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
544404015298	two-component response regulator; Provisional; Region: PRK11173
544404015299	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
544404015300	active site
544404015301	phosphorylation site [posttranslational modification]
544404015302	intermolecular recognition site; other site
544404015303	dimerization interface [polypeptide binding]; other site
544404015304	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
544404015305	DNA binding site [nucleotide binding]
544404015306	putative RNA methyltransferase; Provisional; Region: PRK10433
544404015307	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
544404015308	Peptidase M66; Region: Peptidase_M66; pfam10462
544404015309	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
544404015310	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
544404015311	type II secretion system protein D; Region: type_II_gspD; TIGR02517
544404015312	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
544404015313	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
544404015314	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
544404015315	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
544404015316	type II secretion system protein E; Region: type_II_gspE; TIGR02533
544404015317	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
544404015318	Walker A motif; other site
544404015319	ATP binding site [chemical binding]; other site
544404015320	Walker B motif; other site
544404015321	type II secretion system protein F; Region: GspF; TIGR02120
544404015322	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
544404015323	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
544404015324	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
544404015325	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
544404015326	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
544404015327	type II secretion system protein I; Region: gspI; TIGR01707
544404015328	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
544404015329	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
544404015330	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
544404015331	type II secretion system protein J; Region: gspJ; TIGR01711
544404015332	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
544404015333	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
544404015334	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
544404015335	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
544404015336	GspL periplasmic domain; Region: GspL_C; pfam12693
544404015337	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
544404015338	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
544404015339	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
544404015340	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
544404015341	lipoprotein, PulS/OutS family; Region: PulS_OutS; TIGR01004
544404015342	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404015343	Transposase; Region: HTH_Tnp_1; pfam01527
544404015344	putative transposase OrfB; Reviewed; Region: PHA02517
544404015345	HTH-like domain; Region: HTH_21; pfam13276
544404015346	Integrase core domain; Region: rve; pfam00665
544404015347	Integrase core domain; Region: rve_3; pfam13683
544404015348	RTX toxin acyltransferase family; Region: HlyC; pfam02794
544404015349	RTX N-terminal domain; Region: RTX; pfam02382
544404015350	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
544404015351	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
544404015352	RTX C-terminal domain; Region: RTX_C; pfam08339
544404015353	A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases.  Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine...; Region: Peptidase_C39_likeA; cd02417
544404015354	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
544404015355	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
544404015356	ATP-binding cassette domain of hemolysin B, subfamily C; Region: ABCC_Hemolysin; cd03252
544404015357	Walker A/P-loop; other site
544404015358	ATP binding site [chemical binding]; other site
544404015359	Q-loop/lid; other site
544404015360	ABC transporter signature motif; other site
544404015361	Walker B; other site
544404015362	D-loop; other site
544404015363	H-loop/switch region; other site
544404015364	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
544404015365	HlyD family secretion protein; Region: HlyD_3; pfam13437
544404015366	MarR family; Region: MarR_2; cl17246
544404015367	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
544404015368	active site
544404015369	catalytic residues [active]
544404015370	DNA binding site [nucleotide binding]
544404015371	Int/Topo IB signature motif; other site
544404015372	Initiator Replication protein; Region: Rep_3; cl03080
544404015373	Plasmid replication region DNA-binding N-term; Region: KfrA_N; pfam11740
544404015374	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
544404015375	putative transposase OrfB; Reviewed; Region: PHA02517
544404015376	HTH-like domain; Region: HTH_21; pfam13276
544404015377	Integrase core domain; Region: rve; pfam00665
544404015378	Integrase core domain; Region: rve_3; pfam13683
544404015379	Transposase; Region: HTH_Tnp_1; cl17663
544404015380	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404015381	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
544404015382	Phage integrase family; Region: Phage_integrase; pfam00589
544404015383	active site
544404015384	DNA binding site [nucleotide binding]
544404015385	Int/Topo IB signature motif; other site
544404015386	putative transposase OrfB; Reviewed; Region: PHA02517
544404015387	HTH-like domain; Region: HTH_21; pfam13276
544404015388	Integrase core domain; Region: rve; pfam00665
544404015389	Integrase core domain; Region: rve_3; pfam13683
544404015390	Transposase; Region: HTH_Tnp_1; cl17663
544404015391	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404015392	replication protein; Provisional; Region: PRK13742
544404015393	plasmid-partitioning protein SopA; Provisional; Region: PRK13705
544404015394	MerR family regulatory protein; Region: MerR; pfam00376
544404015395	DNA binding residues [nucleotide binding]
544404015396	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
544404015397	P-loop; other site
544404015398	Magnesium ion binding site [ion binding]; other site
544404015399	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
544404015400	Magnesium ion binding site [ion binding]; other site
544404015401	plasmid-partitioning protein; Provisional; Region: PRK13698
544404015402	ParB-like nuclease domain; Region: ParB; smart00470
544404015403	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
544404015404	putative methylase; Provisional; Region: PRK13699
544404015405	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
544404015406	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
544404015407	Protein of unknown function (DUF1472); Region: DUF1472; pfam07339
544404015408	Antirestriction protein; Region: Antirestrict; pfam03230
544404015409	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
544404015410	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
544404015411	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
544404015412	S-adenosylmethionine binding site [chemical binding]; other site
544404015413	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
544404015414	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
544404015415	dimer interface [polypeptide binding]; other site
544404015416	ssDNA binding site [nucleotide binding]; other site
544404015417	tetramer (dimer of dimers) interface [polypeptide binding]; other site
544404015418	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
544404015419	ParB-like nuclease domain; Region: ParBc; pfam02195
544404015420	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
544404015421	KorB domain; Region: KorB; pfam08535
544404015422	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
544404015423	plasmid SOS inhibition protein A; Provisional; Region: PRK13704
544404015424	small toxic polypeptide; Provisional; Region: PRK09738
544404015425	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
544404015426	TolA C-terminal; Region: TolA; pfam06519
544404015427	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
544404015428	Integrase core domain; Region: rve; pfam00665
544404015429	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
544404015430	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cl17402
544404015431	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
544404015432	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
544404015433	TcdB toxin N-terminal helical domain; Region: TcdB_N; pfam12918
544404015434	TcdA/TcdB catalytic glycosyltransferase domain; Region: TcdA_TcdB; pfam12919
544404015435	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
544404015436	cysteine protease domain, YopT-type; Region: yopT_cys_prot; TIGR01586
544404015437	Protein of unknown function (DUF3491); Region: DUF3491; pfam11996
544404015438	putative transposase OrfB; Reviewed; Region: PHA02517
544404015439	Transposase; Region: HTH_Tnp_1; cl17663
544404015440	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404015441	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
544404015442	DNA helicase TraI; Region: TraI; pfam07057
544404015443	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
544404015444	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
544404015445	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
544404015446	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
544404015447	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
544404015448	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
544404015449	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
544404015450	putative RNA binding sites [nucleotide binding]; other site
544404015451	Staphylococcal nuclease homologues; Region: SNc; smart00318
544404015452	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
544404015453	Catalytic site; other site
544404015454	Haemolysin expression modulating protein; Region: HHA; pfam05321
544404015455	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
544404015456	replication protein; Provisional; Region: PRK13702
544404015457	leader peptide RepL; Provisional; Region: PRK13716
544404015458	replication protein; Provisional; Region: PRK13750
544404015459	Predicted transcriptional regulator [Transcription]; Region: COG3905
544404015460	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
544404015461	Putative transposase; Region: Y2_Tnp; pfam04986
544404015462	Integrase core domain; Region: rve; pfam00665
544404015463	Integrase core domain; Region: rve_3; pfam13683
544404015464	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
544404015465	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
544404015466	dimer interface [polypeptide binding]; other site
544404015467	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
544404015468	active site
544404015469	heme binding site [chemical binding]; other site
544404015470	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
544404015471	Cytochrome b562; Region: Cytochrom_B562; pfam07361
544404015472	putative transposase OrfB; Reviewed; Region: PHA02517
544404015473	HTH-like domain; Region: HTH_21; pfam13276
544404015474	Integrase core domain; Region: rve; pfam00665
544404015475	Integrase core domain; Region: rve_3; pfam13683
544404015476	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
544404015477	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
544404015478	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
544404015479	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
544404015480	Autotransporter beta-domain; Region: Autotransporter; pfam03797
544404015481	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
544404015482	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
544404015483	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
544404015484	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
544404015485	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
544404015486	putative active site [active]
544404015487	putative metal binding site [ion binding]; other site
544404015488	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
544404015489	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
544404015490	hypothetical protein; Provisional; Region: PRK10649
544404015491	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
544404015492	Sulfatase; Region: Sulfatase; pfam00884
544404015493	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
544404015494	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
544404015495	putative acyl-acceptor binding pocket; other site
544404015496	Transposase; Region: HTH_Tnp_1; pfam01527
544404015497	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404015498	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404015499	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
544404015500	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
544404015501	homodimer interface [polypeptide binding]; other site
544404015502	putative GKAP docking site [polypeptide binding]; other site
544404015503	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
544404015504	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
544404015505	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
544404015506	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
544404015507	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
544404015508	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
544404015509	Transposase; Region: HTH_Tnp_1; cl17663