-- dump date   	20111121_012109
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_002389853.1	involved in threonine biosynthesis; controls the expression of the thrLABC operon
YP_002389854.1	multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
YP_002389855.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_002389856.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_002389857.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389858.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389859.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002389860.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 92334977, 11298760, 7592346, 8805555, 9007983, 9298646; Product type e : enzyme
YP_002389861.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
YP_002389862.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002389863.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8478327; Product type r : regulator
YP_002389864.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389865.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002389866.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002389867.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136075, 92048480, 92048481, 99291074; Product type r : regulator
YP_002389868.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389869.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002389870.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389871.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
YP_002389872.1	Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC
YP_002389873.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_002389874.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389875.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_002389876.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_002389877.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_002389878.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97332650, 2011499; Product type e : enzyme
YP_002389879.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_002389880.1	catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides
YP_002389881.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389882.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_002389883.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_002389884.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_002389885.1	Evidence 6 : Doubtful CDS
YP_002389886.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002389887.1	regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons
YP_002389888.1	involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities
YP_002389889.1	catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA
YP_002389890.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15731894, 97189569, 7815937; Product type e : enzyme
YP_002389891.1	catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine
YP_002389892.1	catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA
YP_002389893.1	catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism
YP_002389894.1	required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase
YP_002389895.1	involved in electron transfer during carnitine metabolism
YP_002389896.1	FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction
YP_002389897.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96066354, 12081978; Product type pc : putative carrier
YP_002389898.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002389899.1	Required for full activity of KefC, a potassium-proton antiporter
YP_002389900.1	transport system that facilitates potassium-efflux
YP_002389901.1	catalyzes the reduction of dihydrofolate to tetrahydrofolate
YP_002389902.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002389903.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
YP_002389904.1	protein associated with Co2+ and Mg2+ efflux
YP_002389905.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_002389906.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_002389907.1	Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB
YP_002389908.1	determines N-hexane tolerance and is involved in outer membrane permeability
YP_002389909.1	functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system
YP_002389910.1	catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs
YP_002389911.1	transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA
YP_002389912.1	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C
YP_002389913.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_002389914.1	catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism
YP_002389915.1	catalyzes the phosphorylation of ribulose to ribulose 5-phosphate
YP_002389916.1	positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose
YP_002389917.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389918.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389919.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002389920.1	with TbpA and ThiP is part of the thiamine and TPP transport system
YP_002389921.1	permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine
YP_002389922.1	part of the thiamine and TPP transport system tbpA-thiPQ
YP_002389923.1	activates sgrS under glucose-phosphate stress conditions
YP_002389924.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389925.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_002389926.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_002389927.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_002389928.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_002389929.1	involved in attenuation control of the leuABCD operon in leucine biosynthesis
YP_002389930.1	activator for leuABCD operon; member of LysR family of transcriptional activators
YP_002389931.1	catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive
YP_002389932.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_002389933.1	binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism
YP_002389934.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_002389935.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042184, 10493123, 2187182, 6350821; Product type e : enzyme
YP_002389936.1	membrane bound cell division protein at septum containing leucine zipper motif
YP_002389937.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91072213, 92202178, 94095121, 9603865, 9614966, 1332942, 1447153, 2198024, 2677607, 2681146, 3049550, 3911028, 6350821; Product type e : enzyme
YP_002389938.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_002389939.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88273095, 90248455, 91310568, 97128642, 11090285, 2668880, 9166795; Product type e : enzyme
YP_002389940.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_002389941.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_002389942.1	integral membrane protein involved in stabilizing FstZ ring during cell division
YP_002389943.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002389944.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_002389945.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002389946.1	involved in septum formation
YP_002389947.1	ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane
YP_002389948.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_002389949.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_002389950.1	secM translational pause allows for the initiation of secA translation
YP_002389951.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_002389952.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10218109, 89264540, 90136514, 91225007, 97444511, 1309939, 2841285, 3033442, 3288626, 7578113, 9063868; Product type e : enzyme
YP_002389953.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12211008, 3033442
YP_002389954.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389955.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_002389956.1	catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate
YP_002389957.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96099298, 2904262, 7959070; Product type s : structure
YP_002389958.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96099298, 7959070; Product type pt : putative transporter
YP_002389959.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20100782, 20271862, 96099298, 7959070; Product type ps : putative structure
YP_002389960.1	catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
YP_002389961.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90113890, 95047240, 2607970, 7959070; Product type e : enzyme
YP_002389962.1	involved in regulation of beta-lactamase; putative signaling protein
YP_002389963.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1104763, 90174991, 9150230; Product type t : transporter
YP_002389964.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10702359
YP_002389965.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002389966.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002389967.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002389968.1	activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex
YP_002389969.1	Evidence 6 : Doubtful CDS
YP_002389970.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
YP_002389971.1	E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains
YP_002389972.1	E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002389973.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002389974.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_002389975.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401, 7567469
YP_002389976.1	S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
YP_002389977.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_002389978.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401
YP_002389979.1	laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification
YP_002389980.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10359647, 11604400, 14612441, 91035240, 93123180, 93286127; Product type e : enzyme
YP_002389981.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 13808016, 339828, 6787390, 6801015, 12070315; Product type e : enzyme
YP_002389982.1	catalyzes the interconversion of bicarbonate and carbon dioxide
YP_002389983.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002389984.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10474187; Product type pt : putative transporter
YP_002389985.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002389986.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002389987.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_002389988.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11319082; Product type pe : putative enzyme
YP_002389989.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_002389990.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_002389991.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8096212; Product type ps : putative structure
YP_002389992.1	Evidence 2b : Function of strongly homologous gene; Product type ps : putative structure
YP_002389993.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002389994.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002389995.1	similar to the fimbrial usher protein PapC
YP_002389996.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 93352405, 8102362, 15561151; Product type f : factor
YP_002389997.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002389998.1	catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP
YP_002389999.1	Polymerase that creates the 3' poly(A) tail found in some mRNA's
YP_002390000.1	this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu
YP_002390001.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294157, 90202727, 2013578, 9298646, 9600841; Product type r : regulator
YP_002390002.1	Regulatory factor involved in maltose metabolism
YP_002390003.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97094878; Product type e : enzyme
YP_002390004.1	similar in sequence to the ATP-dependent RNA helicase HrpA
YP_002390005.1	bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell
YP_002390006.1	involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein
YP_002390007.1	part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter
YP_002390008.1	Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores
YP_002390009.1	part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome
YP_002390010.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_002390011.1	Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation
YP_002390012.1	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors
YP_002390013.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390014.1	solute binding component of the vitamin B12 transport system BtuCDF
YP_002390015.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_002390016.1	forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate
YP_002390017.1	protease Do; required at high temperature; degrades damaged proteins
YP_002390018.1	regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization
YP_002390019.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390020.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_002390021.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein
YP_002390022.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_002390023.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_002390024.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_002390025.1	Catalyzes the phosphorylation of UMP to UDP
YP_002390026.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_002390027.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_002390028.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
YP_002390029.1	catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate
YP_002390030.1	catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response
YP_002390031.1	part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins
YP_002390032.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15101556, 90201355, 97032152, 99386928, 1987124, 2843433, 9298646, 2167239; Product type f : factor
YP_002390033.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_002390034.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_002390035.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_002390036.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
YP_002390037.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_002390038.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_002390039.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_002390040.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme
YP_002390041.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390042.1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase
YP_002390043.1	Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination
YP_002390044.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390045.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390046.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390047.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11830644, 95362641, 95362642; Product type lp : lipoprotein
YP_002390048.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002390049.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002390050.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390051.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93094132; Product type pr : putative regulator
YP_002390052.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12169620, 12218041, 12819857, 1459951; Product type t : transporter
YP_002390053.1	part of the MetNIQ methionine uptake system
YP_002390054.1	part of the metNIQ transport system for methionine
YP_002390055.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
YP_002390056.1	catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid
YP_002390057.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390058.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1663890
YP_002390059.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390060.1	catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall
YP_002390061.1	catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione
YP_002390062.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390063.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_002390064.1	3'-5' exonuclease of DNA polymerase III
YP_002390065.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390066.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390067.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390068.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390069.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390070.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390071.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002390072.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390073.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390074.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390075.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390076.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390077.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390078.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390079.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390080.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390081.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390082.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390083.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390084.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390085.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390086.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390087.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390088.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390089.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390090.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8526497; Product type pe : putative enzyme
YP_002390091.1	inactivates vertebrate C-type lysozyme
YP_002390092.1	functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA
YP_002390093.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_002390094.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390095.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390096.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390097.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390098.1	Evidence 7 : Gene remnant; Product type s : structure
YP_002390099.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure
YP_002390100.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002390101.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093, 14594833; Product type pf : putative factor
YP_002390102.1	YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function
YP_002390103.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093; Product type pe : putative enzyme
YP_002390104.1	mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY
YP_002390105.1	similar to release factor 1 and 2
YP_002390106.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1695895, 21101837, 88121730, 92204123, 2651887; Product type e : enzyme
YP_002390107.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
YP_002390108.1	forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation
YP_002390109.1	involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS
YP_002390110.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89178658, 89380253, 92219258, 98090453, 1380671, 1848301, 1848682, 6089111, 6341601, 7679770; Product type t : transporter
YP_002390111.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_002390112.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_002390113.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390114.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12933851, 16081954; Product type e : enzyme
YP_002390115.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002390116.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002390117.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390118.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390119.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390120.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390121.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390122.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390123.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 17563352, 11466275; Product type s : structure
YP_002390124.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390125.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002390126.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390127.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390128.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390129.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390130.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390131.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17575004; Product type pe : putative enzyme
YP_002390132.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002390133.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390134.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390135.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390136.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390137.1	Involved in disulfide oxidoreductase activity and electron transport
YP_002390138.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390139.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390140.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390141.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390142.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390143.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390144.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390145.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390146.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390147.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390148.1	Evidence 6 : Doubtful CDS
YP_002390149.1	catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine
YP_002390150.1	catalyzes the formation of betaine from betaine aldehyde
YP_002390151.1	HTH-type; bet1; Repressor involved in choline regulation of the bet genes
YP_002390152.1	proton-motive-force-driven choline transporter
YP_002390153.1	Evidence 6 : Doubtful CDS
YP_002390154.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995192; Product type e : enzyme
YP_002390155.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390156.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390157.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390158.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390159.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390160.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390161.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7711027, 11523892; Product type pe : putative enzyme
YP_002390162.1	metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain
YP_002390163.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390164.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390165.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390166.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390167.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390168.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390169.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390170.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12879215; Product type t : transporter
YP_002390171.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390172.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9325432, 15805526; Product type r : regulator
YP_002390173.1	catalyzes the formation of pyruvate and succinate from 2-methylisocitrate
YP_002390174.1	catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity
YP_002390175.1	functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C
YP_002390176.1	catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent
YP_002390177.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92349961; Product type t : transporter
YP_002390178.1	Catalyzes the deamination of cytosine to uracil and ammonia
YP_002390179.1	transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown
YP_002390180.1	lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments
YP_002390181.1	forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon
YP_002390182.1	transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer
YP_002390183.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15115803, 12878731, 13129938; Product type e : enzyme
YP_002390184.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800, 15466022; Product type e : enzyme
YP_002390185.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15466022, 87172301, 1731906; Product type e : enzyme
YP_002390186.1	formaldehyde-induced negative regulator of the frmRAB operon
YP_002390187.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390188.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390189.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390190.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390191.1	with TauB and TauC is responsible for taurine uptake.
YP_002390192.1	Part of the ABC transporter complex tauABC involved in taurine import
YP_002390193.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401024, 96404792; Product type t : transporter
YP_002390194.1	catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers
YP_002390195.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_002390196.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002390197.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390198.1	this protein has no known enzymatic function
YP_002390199.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390200.1	in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope
YP_002390201.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390202.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390203.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390204.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002390205.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390206.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002390207.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3533724, 2160940; Product type f : factor
YP_002390208.1	catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis
YP_002390209.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002390210.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390211.1	type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_002390212.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390213.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 86085675, 3001025
YP_002390214.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390215.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390216.1	Required for efficient pilin antigenic variation
YP_002390217.1	catalyzes phosphorylation of fructose; cytosolic enzyme
YP_002390218.1	member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers
YP_002390219.1	with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity
YP_002390220.1	with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity
YP_002390221.1	two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB
YP_002390222.1	membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB
YP_002390223.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3078876, 6998958, 3550103, 7984428; Product type t : transporter
YP_002390224.1	cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation
YP_002390225.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92184757, 1706703, 1918057; Product type e : enzyme
YP_002390226.1	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YP_002390227.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_002390228.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_002390229.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
YP_002390230.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_002390231.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_002390232.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390233.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91092502, 91358319, 93352541; Product type m : membrane component
YP_002390234.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002390235.1	Evidence 2b : Function of strongly homologous gene; Product type r : regulator
YP_002390236.1	riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil
YP_002390237.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_002390238.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_002390239.1	catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP
YP_002390240.1	hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate
YP_002390241.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217, 16077126; Product type e : enzyme
YP_002390242.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_002390243.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89291702, 91210228; Product type e : enzyme
YP_002390244.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_002390245.1	Required for the synthesis of the thiazole moiety
YP_002390246.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 97039868, 99173753, 99311269
YP_002390247.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
YP_002390248.1	putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_002390249.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390250.1	converts protoheme IX and farnesyl diphosphate to heme O
YP_002390251.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 90366572, 92345252, 9378722, 98021084, 11017202, 2162835; Product type c : carrier
YP_002390252.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier
YP_002390253.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier
YP_002390254.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92112945, 92371427, 9378722, 98021084, 11017202, 1322173, 2162835, 2162837, 2165491, 2168206, 8231804, 8618822; Product type c : carrier
YP_002390255.1	in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein
YP_002390256.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002390257.1	positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress
YP_002390258.1	Evidence 6 : Doubtful CDS
YP_002390259.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_002390260.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002390261.1	binds and unfolds substrates as part of the ClpXP protease
YP_002390262.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094703, 14665623, 8939438, 91072263, 97137085, 2984174, 3042779, 3289547, 7988699, 8226758, 8294008; Product type e : enzyme
YP_002390263.1	histone-like DNA-binding protein
YP_002390264.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9670013; Product type e : enzyme
YP_002390265.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390266.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390267.1	YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His
YP_002390268.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390269.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme
YP_002390270.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390271.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004, 10850996; Product type pt : putative transporter
YP_002390272.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004; Product type pt : putative transporter
YP_002390273.1	indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.
YP_002390274.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22020597, 9618533, 10931328, 1645722, 7984428; Product type t : transporter
YP_002390275.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86139906, 91250410, 10876240; Product type e : enzyme
YP_002390276.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390277.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390278.1	Evidence 5 : No homology to any previously reported sequences
YP_002390279.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390280.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390281.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390282.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82180540, 91310703, 9600841; Product type e : enzyme
YP_002390283.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 1956303, 1484495; Product type f : factor
YP_002390284.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1956303, 7984428, 14645275
YP_002390285.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351840, 12654283, 15111118, 15155734, 21450803, 94012493, 10920254, 7651136; Product type t : transporter
YP_002390286.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155734, 21450803, 383699, 390095, 94012493, 10920254, 7651136; Product type t : transporter
YP_002390287.1	regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine
YP_002390288.1	small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS
YP_002390289.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390290.1	PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks
YP_002390291.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390292.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_002390293.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_002390294.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903
YP_002390295.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_002390296.1	molecular chaperone
YP_002390297.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_002390298.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_002390299.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401025, 98244813, 2051480, 7721718; Product type e : enzyme
YP_002390300.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90155203, 95238302, 2051480; Product type e : enzyme
YP_002390301.1	YbaL; member of the CPA-2 family of antiporters; uncharacterized protein
YP_002390302.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 97074653, 8917080; Product type t : transporter
YP_002390303.1	catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides
YP_002390304.1	Evidence 5 : No homology to any previously reported sequences
YP_002390305.1	Evidence 5 : No homology to any previously reported sequences
YP_002390306.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390307.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390308.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002390309.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390310.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351646, 20105527, 11167016, 11500054, 9868784; Product type t : transporter
YP_002390311.1	catalyzes the formation of glutamate from glutamine
YP_002390312.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390313.1	activator of copper-responsive regulon genes
YP_002390318.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390319.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390320.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390321.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390322.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002390323.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390324.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91270121, 91324311, 93163029, 93252782, 94179121, 99353977, 1864840, 8432696, 8098033; Product type e : enzyme
YP_002390325.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390326.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter
YP_002390327.1	catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YP_002390328.1	activator of the allDC-ylbA operon involved in allantoin utilization
YP_002390329.1	catalyzes the formation of glyoxylate from (S)-ureidoglycolate
YP_002390330.1	regulates operons involved in the utilization of allantoin
YP_002390331.1	catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate
YP_002390332.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20029625, 8440684; Product type e : enzyme
YP_002390333.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme
YP_002390334.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1293888; Product type t : transporter
YP_002390335.1	Plays a crucial role on both purine and pyrimidine metabolism
YP_002390336.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390337.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme
YP_002390338.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390339.1	allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide
YP_002390340.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12460564, 20069628, 69151449; Product type e : enzyme
YP_002390341.1	multicopy suppressor of dominant negative ftsH mutations
YP_002390342.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390343.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390344.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2464576, 2644189, 7920643, 7940673, 7984428; Product type pe : putative enzyme
YP_002390345.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_002390346.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10074353, 8117684, 89123018, 89123019, 92287929, 10574791; Product type e : enzyme
YP_002390347.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390348.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
YP_002390349.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 1864365, 8601841, 9298646, 9600841; Product type e : enzyme
YP_002390350.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002390351.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390352.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12837795, 1748668, 7567469; Product type pr : putative regulator
YP_002390353.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_002390354.1	Evidence 6 : Doubtful CDS
YP_002390355.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90036709, 2183007; Product type pe : putative enzyme
YP_002390356.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390357.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390358.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390359.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390360.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390361.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390362.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390363.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390364.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390365.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390366.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390367.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390368.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390369.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390370.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390371.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390372.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390374.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390375.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390376.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390377.1	Evidence 5 : No homology to any previously reported sequences
YP_002390378.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390379.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390380.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390381.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390382.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390383.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme
YP_002390384.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390385.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390386.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390387.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390388.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390389.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390390.1	Evidence 6 : Doubtful CDS
YP_002390391.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390392.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390393.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390394.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390395.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390396.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390397.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390398.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390399.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390400.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390401.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390402.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390403.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390404.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390405.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390406.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390407.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390408.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390409.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390410.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390411.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390412.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390413.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390414.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390415.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390416.1	outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA
YP_002390417.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390418.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390419.1	outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA
YP_002390420.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390421.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component
YP_002390422.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component
YP_002390423.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 11283292, 11399769; Product type r : regulator
YP_002390424.1	response regulator in two-component regulatory system with CusS; regulates the copper efflux system
YP_002390425.1	with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver
YP_002390426.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 21125583, 11283292, 11399769, 12813074; Product type f : factor
YP_002390427.1	with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver
YP_002390428.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 21125583, 21178899, 21450803, 11399769, 12813074, 1711024, 7984428; Product type t : transporter
YP_002390429.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91267923, 94042931, 8626334; Product type t : transporter
YP_002390430.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390431.1	catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive
YP_002390432.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390433.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390434.1	ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity
YP_002390435.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99291074; Product type f : factor
YP_002390436.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89313305, 90132534, 91035252, 8939709, 9214294; Product type e : enzyme
YP_002390437.1	Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space
YP_002390438.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92291125, 94198561, 2974033; Product type e : enzyme
YP_002390439.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390440.1	with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin
YP_002390441.1	part of the ferric enterobactin transport system; necessary for enetrobactin uptake
YP_002390442.1	with FepBDE is involved in the transport of ferric enterobactin
YP_002390443.1	with FepBCD is involved in the transport of ferric enterobactin
YP_002390444.1	with FepBCG is involved in the transport of ferric enterobactin
YP_002390445.1	protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters
YP_002390446.1	with FepCDG is involved in the transport of ferric enterobactin
YP_002390447.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123153, 90165423, 90241936, 2110093, 2139473; Product type e : enzyme
YP_002390448.1	bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate
YP_002390449.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20183918, 90241937, 91035252, 9485415, 97361959, 2521621, 2521622; Product type e : enzyme
YP_002390450.1	catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin
YP_002390451.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2521621, 2521622, 15808744; Product type pe : putative enzyme
YP_002390452.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91162636, 2521622; Product type pf : putative factor
YP_002390453.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390454.1	member of the iron-containing alcohol dehydrogenase family; unknown function
YP_002390455.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator
YP_002390456.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator
YP_002390457.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390458.1	Involved in disulfide bond formation
YP_002390459.1	with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate
YP_002390460.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89197774, 1592833; Product type e : enzyme
YP_002390461.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12071968; Product type f : factor
YP_002390462.1	Evidence 5 : No homology to any previously reported sequences
YP_002390463.1	Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation
YP_002390464.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90151658, 90264307, 2253883, 8188249; Product type e : enzyme
YP_002390465.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9696764; Product type t : transporter
YP_002390466.1	catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA
YP_002390467.1	2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate
YP_002390468.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme
YP_002390469.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme
YP_002390470.1	acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate
YP_002390471.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme
YP_002390472.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11889485, 21885746, 9701802; Product type r : regulator
YP_002390473.1	regulates the expression of citAB in citrate fermentation
YP_002390474.1	responsible for the transport of C4-dicarboxylates during anaerobic growth
YP_002390475.1	catalyzes the transfer of palmitate to lipid A
YP_002390476.1	member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator
YP_002390477.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002390478.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390479.1	TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_002390480.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_002390481.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_002390482.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8444795
YP_002390483.1	penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors
YP_002390484.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88058785, 2644207; Product type lp : lipoprotein
YP_002390485.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123070, 90036736, 91072213, 3316191; Product type cp : cell process
YP_002390486.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86196149, 87030266, 89174517, 2644207; Product type e : enzyme
YP_002390487.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_002390488.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390489.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7929373; Product type pe : putative enzyme
YP_002390490.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_002390491.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_002390492.1	rare lipoprotein B; involved in the assembly of LPS in the outer membrane
YP_002390493.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_002390494.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11373298, 12105207, 3320963, 7567469
YP_002390495.1	Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific
YP_002390496.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter
YP_002390497.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter
YP_002390498.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter
YP_002390499.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1091636, 1091635, 10493123, 8740179, 10972807; Product type t : transporter
YP_002390500.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390501.1	Transfers the fatty acyl group on membrane lipoproteins
YP_002390502.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779764; Product type pt : putative transporter
YP_002390503.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511207; Product type pe : putative enzyme
YP_002390504.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12762842; Product type pe : putative enzyme
YP_002390505.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_002390506.1	catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q
YP_002390508.1	functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP
YP_002390509.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16430214, 89343637; Product type e : enzyme
YP_002390510.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15066032, 90136533, 91171292, 92114782, 92356048, 2190615, 2668691, 7545108; Product type r : regulator
YP_002390511.1	catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate
YP_002390512.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
YP_002390513.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002390514.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390515.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390516.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390517.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390518.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390519.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_002390520.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390521.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002390522.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2118530, 9636669; Product type pt : putative transporter
YP_002390523.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002390524.1	negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer
YP_002390525.1	Evidence 6 : Doubtful CDS
YP_002390526.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002390527.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20223640, 12427949; Product type cp : cell process
YP_002390528.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme
YP_002390529.1	negative modulator of the initiation of chromosome replication
YP_002390530.1	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate
YP_002390531.1	catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system
YP_002390532.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92041955; Product type e : enzyme
YP_002390533.1	response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport
YP_002390534.1	sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein
YP_002390535.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
YP_002390536.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002390537.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002390538.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 6146979; Product type f : factor
YP_002390539.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390540.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6325460, 8387990
YP_002390541.1	UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent
YP_002390542.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15175316; Product type pt : putative transporter
YP_002390543.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14519207
YP_002390544.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390545.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390546.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : putative enzyme
YP_002390547.1	5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity
YP_002390548.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8002588; Product type ph : phenotype
YP_002390549.1	type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH
YP_002390550.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6237244, 89076355, 89123360, 9521736, 99414342, 11259408, 3309132, 6383359, 9822661; Product type m : membrane component
YP_002390551.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82124790, 89076355, 9521736, 99414342, 6383359; Product type m : membrane component
YP_002390552.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_002390553.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_002390554.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_002390555.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
YP_002390556.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_002390557.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_002390558.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390559.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 1689724, 1724280, 2843510, 3138232; Product type c : carrier
YP_002390560.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 2843510, 3138232; Product type c : carrier
YP_002390561.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390562.1	catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components
YP_002390563.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
YP_002390564.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
YP_002390565.1	inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins
YP_002390566.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_002390567.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790745, 87133578, 92244043, 99403391, 11173492, 2687247; Product type lp : lipoprotein
YP_002390568.1	periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity
YP_002390569.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_002390570.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 219824, 90330519; Product type t : transporter
YP_002390571.1	involved in zinc efflux across the cytoplasmic membrane
YP_002390572.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390573.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_002390574.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_002390575.1	catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose
YP_002390576.1	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
YP_002390577.1	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P
YP_002390578.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 8931134, 9174344, 9271499, 9708982; Product type e : enzyme
YP_002390579.1	contains 2 ATP-binding cassettes; involved in the transport of molybdenum
YP_002390580.1	represses the modABCD operon and activates the moaABCD and napFDAGHBC operons
YP_002390581.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390582.1	with ModCB is involved in the high-affinity transport of molybdate
YP_002390583.1	part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE
YP_002390584.1	Part of the ABC transporter complex modABC involved in molybdenum import
YP_002390585.1	YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily
YP_002390586.1	catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
YP_002390587.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390588.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390589.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11782506; Product type pe : putative enzyme
YP_002390590.1	outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family
YP_002390591.1	YbhB; similar to rat and human kinase inhibitory proteins
YP_002390592.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
YP_002390593.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11834738, 12475249, 14704425, 14967041, 20250955, 89066784, 94170810, 94190882, 97382445, 11686925; Product type e : enzyme
YP_002390594.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
YP_002390595.1	putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth
YP_002390596.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002390597.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_002390598.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16272399; Product type pe : putative enzyme
YP_002390599.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_002390600.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93368423; Product type pf : putative factor
YP_002390601.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
YP_002390602.1	catalyzes the conversion of molybdopterin precursor Z into molybdopterin
YP_002390603.1	catalyzes the conversion of molybdopterin precursor Z into molybdopterin
YP_002390604.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390605.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390606.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390607.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20102623, 10634942; Product type e : enzyme
YP_002390608.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390609.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390610.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390611.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390612.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390613.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16092522; Product type pt : putative transporter
YP_002390614.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390615.1	this helicase is not essential cell growth
YP_002390616.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390617.1	helicase involved in DNA repair and perhaps also replication
YP_002390618.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390619.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8405966; Product type pe : putative enzyme
YP_002390620.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390621.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390622.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390623.1	Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein
YP_002390624.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390625.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390626.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390627.1	similar to ATP-binding component of ABC transporters
YP_002390628.1	similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine
YP_002390629.1	similar to periplasmic-binding component of ABC transporters
YP_002390630.1	binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage
YP_002390631.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12648727, 8021175; Product type t : transporter
YP_002390632.1	OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains
YP_002390633.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16514146; Product type pe : putative enzyme
YP_002390634.1	Evidence 6 : Doubtful CDS
YP_002390635.1	Transcriptional regulator that represses the manganese transporter MntH when manganese is present
YP_002390636.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390637.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10493123, 9298646
YP_002390638.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11916677; Product type pt : putative transporter
YP_002390639.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15657928; Product type e : enzyme
YP_002390640.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16218870; Product type pe : putative enzyme
YP_002390641.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581584; Product type pe : putative enzyme
YP_002390642.1	similar to transaldolase from Escherichia coli; many organisms have multiple copies
YP_002390643.1	ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase
YP_002390644.1	is involved in the formation of active molybdenum cofactor and the chelation of molybdenum
YP_002390645.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15159592, 20508248, 3045084, 7984428; Product type e : enzyme
YP_002390646.1	with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains
YP_002390647.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pt : putative transporter
YP_002390648.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390649.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390650.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390651.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pe : putative enzyme
YP_002390652.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
YP_002390653.1	BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
YP_002390654.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16522795, 16864586; Product type e : enzyme
YP_002390655.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390656.1	penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
YP_002390657.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89231635, 89336786, 92231401, 2994018; Product type r : regulator
YP_002390658.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme
YP_002390659.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10022825, 12578981, 14688269, 21217867, 21450803, 9079913, 9644262, 99030337, 8655497; Product type t : transporter
YP_002390660.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390661.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme
YP_002390662.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390663.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390664.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390665.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390666.1	functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase
YP_002390667.1	YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function
YP_002390668.1	NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds
YP_002390669.1	responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6
YP_002390670.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390671.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992, 9651355, 9298646, 8416922; Product type t : transporter
YP_002390672.1	part of the PotFGHI ATP-dependent putrescine transporter
YP_002390673.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter
YP_002390674.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter
YP_002390675.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390676.1	RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA
YP_002390677.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422; Product type t : transporter
YP_002390678.1	with ArtPQJI acts to transport arginine across the inner membrane
YP_002390679.1	with ArtPMJI transports arginine across the inner membrane
YP_002390680.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422, 9740056; Product type t : transporter
YP_002390681.1	With ArtMQJI transports arginine across the inner membrane
YP_002390682.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390683.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390684.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390685.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390686.1	low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine
YP_002390687.1	catalyzes the formation of acetate from pyruvate
YP_002390688.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20117674; Product type e : enzyme
YP_002390689.1	catalyzes the reduction of hydroxylamine to ammonia and water
YP_002390690.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390691.1	Evidence 6 : Doubtful CDS
YP_002390692.1	porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure
YP_002390693.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390694.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390695.1	confers macrolide resistance via active drug efflux
YP_002390696.1	with MacA is involved in the export of macrolide
YP_002390697.1	inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible
YP_002390698.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
YP_002390699.1	ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates
YP_002390700.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390701.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390702.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390703.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390704.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390705.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_002390706.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
YP_002390707.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
YP_002390708.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
YP_002390709.1	catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding
YP_002390710.1	mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system
YP_002390711.1	DNA-binding membrane protein required for chromosome resolution and partitioning
YP_002390712.1	participates with LolB in the incorporation of lipoprotein into the outer membrane
YP_002390713.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7567469, 7628437, 11459952, 11029431; Product type cp : cell process
YP_002390714.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002390715.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 94171715, 10801884, 3062312; Product type e : enzyme
YP_002390716.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91070067, 91355180, 92011349, 3062312; Product type e : enzyme
YP_002390717.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 3062312, 8429002; Product type e : enzyme
YP_002390718.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9782055, 3062312, 11714269; Product type pe : putative enzyme
YP_002390719.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002390720.1	activates pyruvate formate-lyase 1 under anaerobic conditions
YP_002390721.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91064082, 92276323, 10504733, 1310545, 2651404, 3053170, 9629924; Product type e : enzyme
YP_002390722.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293770, 2651404; Product type t : transporter
YP_002390723.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390724.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390725.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_002390726.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_002390727.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002390728.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_002390729.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_002390730.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_002390731.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390732.1	involved in the transport of lipid A across the inner membrane
YP_002390733.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_002390734.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390735.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390736.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_002390737.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390738.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390739.1	involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA
YP_002390740.1	acts with MukB and MukE to condense the chromosome and allow for segregation during cell division
YP_002390741.1	acts with MukB and MukF to condense the chromosome and allow for segregation during cell division
YP_002390742.1	SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects
YP_002390743.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390744.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390745.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14529289; Product type pe : putative enzyme
YP_002390746.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_002390747.1	outer membrane porin F; 1a; Ia; b
YP_002390748.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002390749.1	catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate
YP_002390750.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101837, 86164315, 87163509, 2436977, 3018440; Product type e : enzyme
YP_002390751.1	part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease
YP_002390752.1	part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease
YP_002390753.1	catalyzes the release of sulfite from alkanesulfonates
YP_002390754.1	part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease
YP_002390755.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20245523, 99410391, 99436146, 8774726; Product type e : enzyme
YP_002390756.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_002390757.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390758.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1327782; Product type pe : putative enzyme
YP_002390759.1	catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA
YP_002390760.1	Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth
YP_002390761.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process
YP_002390762.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process
YP_002390763.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390764.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1101029, 90207255, 2832401, 8440252; Product type f : factor
YP_002390765.1	catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP
YP_002390766.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390767.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390768.1	OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d
YP_002390769.1	Evidence 6 : Doubtful CDS
YP_002390770.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10368140, 91072263, 93163041, 98348458, 3297925, 6253901, 6306396; Product type cp : cell process
YP_002390771.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390772.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390773.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390774.1	catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand
YP_002390775.1	catalyzes the formation of methylglyoxal from glycerone phosphate
YP_002390776.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390777.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390778.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700277, 15569148; Product type f : factor
YP_002390779.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390780.1	catalyzes the hydrolysis of acylphosphate
YP_002390781.1	transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs
YP_002390782.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6376117; Product type m : membrane component
YP_002390783.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86192450, 90202716, 92215587; Product type e : enzyme
YP_002390784.1	involved in hydrogen cycling during fermentative growth
YP_002390785.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type c : carrier
YP_002390786.1	HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1)
YP_002390787.1	involved in processing hydrogenase proteins HyaA and HyaB
YP_002390788.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type f : factor
YP_002390789.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier
YP_002390790.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier
YP_002390791.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20122624, 92049231, 93054596, 10696472, 2168385, 3038201, 8387749; Product type e : enzyme
YP_002390792.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9484881, 9439003; Product type f : factor
YP_002390793.1	Evidence 6 : Doubtful CDS
YP_002390794.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 15466053, 8631696, 9439003; Product type r : regulator
YP_002390795.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15317805, 11544213; Product type pr : putative regulator
YP_002390796.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002390797.1	Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide
YP_002390798.1	periplasmic sensory protein associated with the TorRS two-component regulatory system
YP_002390799.1	response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes
YP_002390800.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293785, 94314186, 99340208, 11056172, 11562502; Product type c : carrier
YP_002390801.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193091, 90089471, 94293785, 8302830, 8022286; Product type e : enzyme
YP_002390802.1	TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor
YP_002390803.1	with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA
YP_002390804.1	functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock
YP_002390805.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12455612, 90368616, 91297199, 2153660, 9298646; Product type e : enzyme
YP_002390806.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390807.1	stationary phase protein that binds TrpR repressor
YP_002390808.1	Evidence 6 : Doubtful CDS
YP_002390809.1	Evidence 6 : Doubtful CDS
YP_002390810.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542, 10633095; Product type e : enzyme
YP_002390811.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002390812.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002390813.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002390814.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002390815.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002390816.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type r : regulator
YP_002390817.1	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein
YP_002390818.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12923181, 88213396, 91227628, 93132799, 98359785, 1400239, 1567896, 3053649, 3053687, 3302614, 3325781, 8119910; Product type t : transporter
YP_002390819.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter
YP_002390820.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 10493123; Product type t : transporter
YP_002390821.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 16551627, 15375152; Product type t : transporter
YP_002390822.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8444794, 2160940; Product type pe : putative enzyme
YP_002390823.1	in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export
YP_002390824.1	predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein
YP_002390825.1	in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export
YP_002390826.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 99392474; Product type pe : putative enzyme
YP_002390827.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11237876, 10493123; Product type e : enzyme
YP_002390828.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12661000; Product type pe : putative enzyme
YP_002390829.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390830.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390831.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817489; Product type lp : lipoprotein
YP_002390832.1	nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex
YP_002390833.1	chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex
YP_002390834.1	activates the csgBA and csgDEFG operons involved in biofilm formation
YP_002390835.1	CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface
YP_002390836.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89201357, 93023873, 1677357, 8459772, 8817489, 1357528; Product type s : structure
YP_002390837.1	involved in autoagglutination of curliated cells; not involved in production of curli fibers
YP_002390838.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390839.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390840.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390841.1	required for the transfer of succinyl residues to the glucan backbone
YP_002390842.1	Evidence 6 : Doubtful CDS
YP_002390843.1	Evidence 6 : Doubtful CDS
YP_002390844.1	involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan
YP_002390845.1	necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space
YP_002390846.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002390847.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165719
YP_002390848.1	Confers resistance to fosfomycin and deoxycholate
YP_002390849.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_002390850.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1840644
YP_002390851.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15741337, 11298273, 1840644, 9298646; Product type c : carrier
YP_002390852.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002390853.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390854.1	catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids
YP_002390855.1	BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
YP_002390856.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11230150, 11152126; Product type f : factor
YP_002390857.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_002390858.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002390859.1	cofactor involved in the reduction of disulfides
YP_002390860.1	Confers resistance to norfloxacin and enoxacin
YP_002390861.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88121676, 90136529, 1356970; Product type e : enzyme
YP_002390862.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1356970, 2828880
YP_002390863.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002390864.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390865.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10320579; Product type f : factor
YP_002390866.1	regulates the flagellar specific sigma28 transcription factor
YP_002390867.1	required for the assembly of the flagellar basal body P-ring
YP_002390868.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella
YP_002390869.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_002390870.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production
YP_002390871.1	the hook connects flagellar basal body to the flagellar filament
YP_002390872.1	FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod
YP_002390873.1	makes up the distal portion of the flagellar basal body rod
YP_002390874.1	part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod
YP_002390875.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
YP_002390876.1	Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space
YP_002390877.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
YP_002390878.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes
YP_002390879.1	bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase
YP_002390880.1	catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA
YP_002390881.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002390882.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 90008815, 1447160
YP_002390883.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_002390884.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_002390885.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_002390886.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052166, 92183950, 92210530, 92234941, 7700236, 7768883, 9298646; Product type e : enzyme
YP_002390887.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002390888.1	carries the fatty acid chain in fatty acid biosynthesis
YP_002390889.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002390890.1	catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate
YP_002390891.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390892.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_002390893.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_002390894.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8505303, 8509334, 10747959; Product type pe : putative enzyme
YP_002390895.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002390896.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90286919, 3032906, 10529396; Product type t : transporter
YP_002390897.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15703176, 10493123, 2162465; Product type e : enzyme
YP_002390898.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390899.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002390900.1	catalyzes the phosphorylation of thiamine to thiamine phosphate
YP_002390901.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
YP_002390902.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390903.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766919, 20130027, 81256452, 92296775, 94042945, 99441207, 6265208; Product type e : enzyme
YP_002390904.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6265208, 7984428
YP_002390905.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002390906.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089
YP_002390907.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390908.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14602898, 90158497, 92107993, 8465200; Product type f : factor
YP_002390909.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390910.1	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
YP_002390911.1	outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone
YP_002390912.1	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
YP_002390913.1	catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine
YP_002390914.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_002390915.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390916.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002390917.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate
YP_002390918.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component
YP_002390919.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component
YP_002390920.1	functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase
YP_002390921.1	Evidence 6 : Doubtful CDS
YP_002390922.1	catalyzes the release of the N-terminal amino acid from a tripeptide
YP_002390923.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390924.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105017; Product type r : regulator
YP_002390925.1	response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress
YP_002390926.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_002390927.1	HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis
YP_002390928.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_002390929.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme
YP_002390930.1	catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA
YP_002390931.1	Converts isocitrate to alpha ketoglutarate
YP_002390932.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390933.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390934.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390935.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390936.1	Evidence 6 : Doubtful CDS
YP_002390937.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390938.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390939.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390940.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390941.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin
YP_002390942.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390943.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390944.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390945.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390947.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8335629; Product type h : extrachromosomal origin
YP_002390948.1	Evidence 5 : No homology to any previously reported sequences
YP_002390949.1	Evidence 5 : No homology to any previously reported sequences
YP_002390950.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390951.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390952.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390953.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 375198; Product type h : extrachromosomal origin
YP_002390954.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390955.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390956.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390957.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390958.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390959.1	DLP12 prophage; Holliday junction resolvase
YP_002390960.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : putative factor
YP_002390961.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390962.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme
YP_002390963.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : putative enzyme
YP_002390964.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme
YP_002390965.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 95173101; Product type pm : putative membrane component
YP_002390966.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390967.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390968.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390969.1	Evidence 2b : Function of strongly homologous gene; Product type f : factor
YP_002390970.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390971.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390972.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390973.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390974.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390975.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390976.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390977.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390978.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390979.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390980.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390981.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390982.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390983.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390984.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390985.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390986.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390987.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390988.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002390989.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002390990.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002390991.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390992.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component
YP_002390993.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component
YP_002390994.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component
YP_002390995.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type t : transporter
YP_002390996.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390997.1	Evidence 6 : Doubtful CDS
YP_002390998.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002390999.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391000.1	Evidence 6 : Doubtful CDS
YP_002391001.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16533062, 15453820; Product type pe : putative enzyme
YP_002391002.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391003.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391004.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391005.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391006.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391007.1	Evidence 5 : No homology to any previously reported sequences
YP_002391008.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391009.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391010.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391011.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391012.1	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell
YP_002391013.1	ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums
YP_002391014.1	blocks the formation of polar Z-ring septums
YP_002391015.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391016.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391017.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391018.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15551868; Product type pe : putative enzyme
YP_002391019.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391020.1	binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
YP_002391021.1	binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
YP_002391022.1	disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein
YP_002391023.1	involved in regulation of intracellular pH under alkaline conditions
YP_002391024.1	Multifunctional regulator of fatty acid metabolism
YP_002391025.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391026.1	catalyzes the oxidative deamination of D-amino acids
YP_002391027.1	catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA
YP_002391028.1	the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli
YP_002391029.1	catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine
YP_002391030.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98317285; Product type e : enzyme
YP_002391031.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11031114; Product type cp : cell process
YP_002391032.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002391033.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002391034.1	involved in molybdenum transport
YP_002391035.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391036.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391037.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002391038.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391039.1	periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell
YP_002391040.1	phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL
YP_002391041.1	with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone
YP_002391042.1	with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase
YP_002391043.1	Positively regulates the dhaKLM operon from a sigma-70 promoter
YP_002391044.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391045.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_002391046.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_002391047.1	YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function
YP_002391048.1	putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport
YP_002391049.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_002391050.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_002391051.1	Incorporates lipoproteins in the outer membrane after they are released by the LolA protein
YP_002391052.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_002391053.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_002391054.1	HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB
YP_002391055.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator
YP_002391056.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator
YP_002391057.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_002391058.1	Evidence 2b : Function of strongly homologous gene; Product type f : factor
YP_002391059.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93266586, 94193576, 94292460; Product type t : transporter
YP_002391060.1	in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions
YP_002391061.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator
YP_002391062.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391063.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pf : putative factor
YP_002391064.1	two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase
YP_002391065.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92276349, 92374842, 94083940, 2649492, 2657652, 2668029; Product type r : regulator
YP_002391066.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391067.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91258310, 2657652, 2668029; Product type t : transporter
YP_002391068.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 2233673, 2668029, 2995309, 3053688, 3308846, 6094247; Product type e : enzyme
YP_002391069.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 1321049, 2832376, 3053688, 8383531, 8388253, 8664273, 9516445; Product type c : carrier
YP_002391070.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89384449, 92121125, 9632249, 2832376; Product type f : factor
YP_002391071.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 75114694, 89384449, 92121125, 2832376, 3053688; Product type c : carrier
YP_002391072.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391073.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
YP_002391074.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391075.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391076.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339606, 12912910, 9495753; Product type r : regulator
YP_002391077.1	together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose
YP_002391078.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator
YP_002391079.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_002391080.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 6271469; Product type pe : putative enzyme
YP_002391081.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12783863, 4301680, 89291706, 91200315; Product type e : enzyme
YP_002391082.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391083.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391084.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20256410, 86111605, 90256748, 92325017, 2015910, 9298646, 9600841, 2187863, 8740179, 9740056, 10972807; Product type t : transporter
YP_002391085.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606, 93106975, 2187863; Product type t : transporter
YP_002391086.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter
YP_002391087.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter
YP_002391088.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter
YP_002391089.1	highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein
YP_002391090.1	catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol)
YP_002391091.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391092.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12220501, 12912904, 94224769, 98319474; Product type t : transporter
YP_002391093.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
YP_002391094.1	membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins
YP_002391095.1	YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins
YP_002391096.1	Involved in cell division; probably involved in intracellular septation
YP_002391097.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391098.1	receptor for colicin S4
YP_002391099.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391100.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391101.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391102.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391103.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391104.1	Evidence 6 : Doubtful CDS
YP_002391105.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391106.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391107.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391108.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391109.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391110.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391111.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391112.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391113.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391114.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391115.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391116.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391117.1	Evidence 6 : Doubtful CDS
YP_002391118.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391119.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391120.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391121.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391122.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391123.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391124.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391125.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme
YP_002391126.1	Evidence 6 : Doubtful CDS
YP_002391127.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391128.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391129.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391130.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391131.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391132.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391133.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391134.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391135.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391136.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391137.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391138.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391139.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391140.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391141.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391142.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391143.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391144.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391145.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391146.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391147.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391148.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391149.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391150.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391151.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002391152.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391153.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391154.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391155.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15388941, 3058546, 8455549
YP_002391156.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3058546, 8455549
YP_002391157.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391158.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_002391159.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_002391160.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
YP_002391161.1	bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis
YP_002391162.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_002391163.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002391164.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391165.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391166.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391167.1	catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA
YP_002391168.1	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide
YP_002391169.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391170.1	Evidence 6 : Doubtful CDS
YP_002391171.1	SohB; periplasmic protein; member of the peptidase S49 family
YP_002391172.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029379, 7567469, 9868784
YP_002391173.1	Evidence 6 : Doubtful CDS
YP_002391174.1	Evidence 6 : Doubtful CDS
YP_002391175.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_002391176.1	LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation
YP_002391177.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391178.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391179.1	Catalyzes the conversion of citrate to isocitrate
YP_002391180.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
YP_002391181.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033893, 92104964; Product type e : enzyme
YP_002391182.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391183.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391184.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_002391185.1	involved in start site selection during the initiation of translation
YP_002391186.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 2644204; Product type lp : lipoprotein
YP_002391187.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16451192; Product type r : regulator
YP_002391188.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391189.1	c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP
YP_002391190.1	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YP_002391191.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391192.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_002391193.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391194.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391195.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391196.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391197.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391198.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580; Product type t : transporter
YP_002391199.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580, 1987159; Product type t : transporter
YP_002391200.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter
YP_002391201.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter
YP_002391202.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter
YP_002391203.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391204.1	transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor
YP_002391205.1	involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF
YP_002391206.1	acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding
YP_002391207.1	with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock
YP_002391208.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295203, 97303082; Product type ph : phenotype
YP_002391209.1	rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide
YP_002391210.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391211.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391212.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391213.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391214.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391215.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391216.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391217.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11972617; Product type pe : putative enzyme
YP_002391218.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391219.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20464934, 89327119, 9721282; Product type t : transporter
YP_002391220.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391221.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391222.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391223.1	regulates genes involved in the biosynthesis and transport of aromatic amino acids
YP_002391224.1	antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
YP_002391225.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11747447, 11747448, 7499381; Product type e : enzyme
YP_002391226.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12511517; Product type e : enzyme
YP_002391227.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391228.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391229.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pr : putative regulator
YP_002391230.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438753, 9495761; Product type t : transporter
YP_002391231.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391232.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391233.1	with UspC and UspD is involved in resistance to UV irradiation
YP_002391234.1	Global transcription factor that controls the expression of over 100 target genes in response to anoxia
YP_002391235.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88067749, 91161525, 94252990, 98125595, 1520330; Product type e : enzyme
YP_002391236.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391237.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391238.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391239.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391240.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16045609; Product type pe : putative enzyme
YP_002391241.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391242.1	Evidence 5 : No homology to any previously reported sequences
YP_002391243.1	exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA
YP_002391244.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
YP_002391245.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12381839, 11849540, 9298646; Product type f : factor
YP_002391246.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642192; Product type t : transporter
YP_002391247.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9025293; Product type pe : putative enzyme
YP_002391248.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391249.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12892888, 8349564, 9025293; Product type f : factor
YP_002391250.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4297266, 89123040, 90198524, 8349564, 9025293; Product type e : enzyme
YP_002391251.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391252.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002391253.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391254.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002391255.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391256.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391257.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391258.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391259.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391260.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391261.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
YP_002391262.1	involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain
YP_002391263.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391264.1	NAD-linked
YP_002391265.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9622357, 9019141, 1917845, 3780374; Product type e : enzyme
YP_002391266.1	B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm
YP_002391267.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391268.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391269.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391270.1	involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans
YP_002391271.1	Evidence 6 : Doubtful CDS
YP_002391272.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391273.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89364711; Product type e : enzyme
YP_002391274.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391275.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94222856, 2060788; Product type t : transporter
YP_002391276.1	with TehA confers resistance to tellurite
YP_002391277.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002391278.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1885518; Product type pt : putative transporter
YP_002391279.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391280.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391281.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391282.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : putative regulator
YP_002391283.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11683869; Product type pt : putative transporter
YP_002391284.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391285.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391286.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391287.1	catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation
YP_002391288.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391289.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391290.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391291.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391292.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002391293.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391294.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005443; Product type t : transporter
YP_002391295.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391296.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391297.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391298.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391299.1	Evidence 5 : No homology to any previously reported sequences
YP_002391300.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391301.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme
YP_002391302.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14611652, 15103639, 2233673
YP_002391303.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme
YP_002391304.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410, 92186712; Product type f : factor
YP_002391305.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type c : carrier
YP_002391306.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme
YP_002391307.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95266795, 2233673; Product type t : transporter
YP_002391308.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12410826; Product type t : transporter
YP_002391309.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme
YP_002391310.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005553, 90375017, 92332427, 11884747, 1834669; Product type c : carrier
YP_002391311.1	nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase
YP_002391312.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391313.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
YP_002391314.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
YP_002391315.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10498711, 13129944; Product type f : factor
YP_002391316.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14512736, 91350191, 9298646; Product type m : membrane component
YP_002391317.1	heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate
YP_002391318.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002391319.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960106; Product type lp : lipoprotein
YP_002391320.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15795232, 15489450; Product type t : transporter
YP_002391321.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12912902, 92155241, 92394884, 99406302, 8455549; Product type e : enzyme
YP_002391322.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1659611, 11514505; Product type pe : putative enzyme
YP_002391323.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391324.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391325.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pr : putative regulator
YP_002391326.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391327.1	regulates the cellular response to acid resistance
YP_002391328.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391329.1	in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family
YP_002391330.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002391331.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391332.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391333.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765; Product type r : regulator
YP_002391334.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765, 8021189; Product type r : regulator
YP_002391335.1	catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate
YP_002391336.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391337.1	catalyzes the formation of D-tagaturonate from D-altronate
YP_002391338.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391339.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391340.1	catalyzes the formation of glutamate from glutamine
YP_002391341.1	in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase
YP_002391342.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391343.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094697, 99369894, 8383113, 10438792; Product type t : transporter
YP_002391344.1	protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function
YP_002391345.1	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
YP_002391346.1	transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF
YP_002391347.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8383113
YP_002391348.1	converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism
YP_002391349.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391350.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391351.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391352.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391353.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391354.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20305052; Product type t : transporter
YP_002391355.1	YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters
YP_002391356.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391357.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 216006, 8226676; Product type e : enzyme
YP_002391358.1	NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine
YP_002391359.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391360.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12084818; Product type pc : putative carrier
YP_002391361.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391362.1	Evidence 6 : Doubtful CDS
YP_002391363.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7545940; Product type pe : putative enzyme
YP_002391364.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : putative enzyme
YP_002391365.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391366.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391367.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94357898; Product type e : enzyme
YP_002391368.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391369.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784
YP_002391370.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme
YP_002391371.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme
YP_002391372.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type c : carrier
YP_002391373.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type m : membrane component
YP_002391374.1	binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane
YP_002391375.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12384697; Product type pt : putative transporter
YP_002391376.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002391377.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10318813, 20490366, 6989798, 99340206, 99395104, 99398866, 7766024; Product type r : regulator
YP_002391378.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391379.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391380.1	required for growth and survival under moderately acid conditions
YP_002391381.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391382.1	with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS
YP_002391383.1	with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS
YP_002391384.1	transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes
YP_002391385.1	catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme
YP_002391386.1	forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
YP_002391387.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391388.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1311296; Product type pt : putative transporter
YP_002391389.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14617668; Product type e : enzyme
YP_002391390.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391391.1	response regulator in two-component regulatory system with RstB
YP_002391392.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93086426, 1495392, 1925016, 2646639; Product type r : regulator
YP_002391393.1	binds to DNA replication terminator sequences to prevent passage of replication forks
YP_002391394.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_002391395.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193096, 88268900, 92011457, 3005475, 6328431, 9298646; Product type e : enzyme
YP_002391396.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 6397402; Product type e : enzyme
YP_002391397.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391398.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15774881; Product type t : transporter
YP_002391399.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3534890; Product type t : transporter
YP_002391400.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87041472, 88038341, 2103475, 8125312; Product type e : enzyme
YP_002391401.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88038341, 2823062, 3934044, 11115104; Product type r : regulator
YP_002391402.1	Acts on the hydroxyl group at position 7 of the steroid frame
YP_002391403.1	regulates malXY which are involved in maltose-glucose transport
YP_002391404.1	phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site
YP_002391405.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20164451, 7665481, 91310596; Product type e : enzyme
YP_002391406.1	catalyzes the formation of inosine from adenosine
YP_002391407.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391408.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392465, 10931331; Product type m : membrane component
YP_002391409.1	YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes
YP_002391410.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391411.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411911, 10637328, 12773378; Product type pm : putative membrane component
YP_002391412.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_002391413.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_002391414.1	RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents
YP_002391415.1	part of membrane-bound complex hought to be involved in electron transport to nitrogen
YP_002391416.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
YP_002391417.1	DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines
YP_002391418.1	mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation
YP_002391419.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95096109, 2185038, 9680481; Product type e : enzyme
YP_002391420.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
YP_002391421.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_002391422.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
YP_002391423.1	MliC; membrane-bound lysozyme inhibitor of c-type lysozyme
YP_002391424.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
YP_002391425.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8544813; Product type lp : lipoprotein
YP_002391426.1	Transcription regulator that can both activate or repress expression
YP_002391427.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391428.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12900028; Product type e : enzyme
YP_002391429.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391430.1	SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water
YP_002391431.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391432.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391433.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391434.1	FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide
YP_002391435.1	Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione
YP_002391436.1	Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A)
YP_002391437.1	Evidence 7 : Gene remnant
YP_002391438.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15833738, 15840565, 11950925, 12730244; Product type e : enzyme
YP_002391439.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391440.1	SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals
YP_002391441.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391442.1	binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers
YP_002391443.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404765; Product type pr : putative regulator
YP_002391444.1	uncharacterized member of the major facilitator superfamily (MFS)
YP_002391445.1	catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge
YP_002391446.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_002391447.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
YP_002391448.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391449.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391450.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391451.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391452.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002391453.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002391454.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391455.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391456.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002391457.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391458.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002391459.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 334727, 338599, 322142, 353292, 391404, 4261992, 4575979, 6765942; Product type lp : lipoprotein
YP_002391460.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391461.1	Acts with SufS to catalyze the formation of L-alanine from L-cysteine
YP_002391462.1	catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine
YP_002391463.1	with SufBC activates cysteine desulfurase SufS
YP_002391464.1	part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE
YP_002391465.1	with SufCD activates cysteine desulfurase SufS
YP_002391466.1	functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein
YP_002391467.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391468.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme
YP_002391469.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11102686; Product type pe : putative enzyme
YP_002391470.1	YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function
YP_002391471.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391472.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391473.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391474.1	YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate
YP_002391475.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
YP_002391476.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16253988; Product type e : enzyme
YP_002391477.1	may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain
YP_002391478.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391479.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391480.1	YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain
YP_002391481.1	May play a role in a redox process
YP_002391482.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002391483.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002391484.1	acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids
YP_002391485.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002391486.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391487.1	tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate
YP_002391488.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15039350
YP_002391489.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391490.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391491.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type lp : lipoprotein
YP_002391492.1	ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell
YP_002391493.1	similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane
YP_002391494.1	with BtuD and BtuF transports vitamin B12 into the cell
YP_002391495.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_002391496.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_002391497.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_002391498.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002391499.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_002391500.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93085722, 10094780, 3298224, 3542048, 6325158; Product type s : structure
YP_002391501.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002391504.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391505.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 78194149, 88292964, 6235149, 6310120; Product type e : enzyme
YP_002391506.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391507.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391508.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391509.1	YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate
YP_002391510.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10760155; Product type pm : putative membrane component
YP_002391511.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391512.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9427399; Product type cp : cell process
YP_002391513.1	Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
YP_002391514.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20042356, 1987146, 2179047, 8121401, 9405618
YP_002391515.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042356, 90185127, 9405618; Product type e : enzyme
YP_002391516.1	represses the celABCDF-ydjC operon involved in carbon uptake
YP_002391517.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002391518.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002391519.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002391520.1	osmotically-inducible lipoprotein E; activator of ntr-like gene protein
YP_002391521.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_002391522.1	3' incision activity; acts with UvrC
YP_002391523.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21862596
YP_002391524.1	periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP
YP_002391525.1	catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism
YP_002391526.1	catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation
YP_002391527.1	a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH
YP_002391528.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14675764, 98361920; Product type e : enzyme
YP_002391529.1	catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate
YP_002391530.1	removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction
YP_002391531.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391532.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391533.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391534.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391535.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391536.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391537.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391538.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391539.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component
YP_002391540.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101911; Product type e : enzyme
YP_002391541.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_002391542.1	decatenates replicating daughter chromosomes
YP_002391543.1	catalyzes the formation of selenophosphate from selenide and ATP
YP_002391544.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391545.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391546.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391547.1	SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane
YP_002391548.1	converts asparagine to aspartate and ammonia
YP_002391549.1	catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide
YP_002391550.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391551.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391552.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391553.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391554.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391555.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12897001; Product type pe : putative enzyme
YP_002391556.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391557.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391558.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391559.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
YP_002391560.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 775311, 94131963, 98361923, 1862091, 2124629, 2990926, 7896119, 8636984, 9298646; Product type e : enzyme
YP_002391561.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391562.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391563.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10037771, 20267815; Product type f : factor
YP_002391564.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391565.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391566.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391567.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391568.1	Evidence 6 : Doubtful CDS
YP_002391569.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391570.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391571.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391572.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391573.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391574.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391575.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391576.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391577.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391578.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391579.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88289400, 89053950, 93015723, 8107670; Product type e : enzyme
YP_002391580.1	Activates fatty acids by binding to coenzyme A
YP_002391581.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type lp : lipoprotein
YP_002391582.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391583.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391584.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391585.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391586.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391587.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88025006, 91067712, 91302313, 96011382, 6330050, 7896119; Product type e : enzyme
YP_002391588.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme
YP_002391589.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155761, 89359152, 91056090, 93170282; Product type e : enzyme
YP_002391590.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16513732; Product type pe : putative enzyme
YP_002391591.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002391592.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165962, 90036983, 8131846, 8676384, 9074635, 9298646; Product type t : transporter
YP_002391593.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 87165962, 90036983, 94086520, 97128775, 7811395, 8774730; Product type t : transporter
YP_002391594.1	hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel
YP_002391595.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391596.1	membrane protein YebN
YP_002391597.1	methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth
YP_002391598.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 21101802, 94293754, 12071744, 7984109, 8022261, 9298646, 9868784, 9921691; Product type f : factor
YP_002391599.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391600.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391601.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391602.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391603.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659677, 4359651; Product type r : regulator
YP_002391604.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391605.1	putative metalloprotease
YP_002391606.1	Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3
YP_002391607.1	affects solute and DNA transport through an unknown mechanism
YP_002391608.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391609.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391610.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391611.1	in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA
YP_002391612.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391613.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391614.1	Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins
YP_002391615.1	Evidence 6 : Doubtful CDS
YP_002391616.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391617.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391618.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391619.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15090519, 92147649, 92156151, 94131961, 1575709, 8341603, 8505306; Product type e : enzyme
YP_002391620.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391621.1	3'-5' exonuclease activity on single or double-strand DNA
YP_002391622.1	PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues
YP_002391623.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391624.1	secreted protein; unknown function
YP_002391625.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9368369, 99403401; Product type cp : cell process
YP_002391626.1	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis
YP_002391627.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
YP_002391628.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
YP_002391630.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002391631.1	Represses the expression of the zwf, eda, glp and gap
YP_002391632.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002391633.1	Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
YP_002391634.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732206; Product type pe : putative enzyme
YP_002391635.1	involved in transport of zinc(II) with ZnuA and C
YP_002391636.1	involved in transport of zinc(II) with ZnuA and C
YP_002391637.1	involved in transport of zinc(II) with ZnuA and C
YP_002391638.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_002391639.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_002391640.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391641.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_002391642.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391643.1	converts dATP to dAMP and pyrophosphate
YP_002391644.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002391645.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391646.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2129559, 7984428
YP_002391647.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391648.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11746687; Product type e : enzyme
YP_002391649.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391650.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97077292, 11004177; Product type e : enzyme
YP_002391651.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461225, 8919859; Product type c : carrier
YP_002391652.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95362641, 7635807; Product type t : transporter
YP_002391653.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12660999; Product type pe : putative enzyme
YP_002391654.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002391655.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8002587, 1482109, 89181349
YP_002391656.1	membrane protein involved in the flagellar export apparatus
YP_002391657.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
YP_002391658.1	cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation
YP_002391659.1	chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble
YP_002391660.1	regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins
YP_002391661.1	methylates the MCP
YP_002391662.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094243, 92165727, 6305515, 9315712; Product type r : regulator
YP_002391663.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91126073, 91296802, 91317710, 2002011, 3510184; Product type r : regulator
YP_002391664.1	chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component
YP_002391665.1	with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002391666.1	With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002391667.1	With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems
YP_002391668.1	with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems
YP_002391669.1	ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
YP_002391670.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 92121128, 93302496, 8045430; Product type e : enzyme
YP_002391671.1	biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature
YP_002391672.1	Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose
YP_002391673.1	Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose
YP_002391674.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89255061, 90375534, 2445996, 326784, 326785, 6885805, 7031057, 9298646; Product type t : transporter
YP_002391675.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002391676.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391677.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391678.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391679.1	cytoplasmic iron storage protein
YP_002391680.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391681.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89008121, 2022620; Product type t : transporter
YP_002391682.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391683.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 381294, 7007311, 94253011, 1323047, 3003065, 8917447; Product type e : enzyme
YP_002391684.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_002391685.1	in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system
YP_002391686.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3515318, 7567469
YP_002391687.1	regulates genes involved in cell division
YP_002391688.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391689.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391690.1	catalyzes the formation of pyruvate from D-cysteine
YP_002391691.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125225, 8450713, 8774726, 9298646, 9740056; Product type t : transporter
YP_002391692.1	expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence
YP_002391693.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes
YP_002391694.1	structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes
YP_002391695.1	involved in flagellin assembly
YP_002391696.1	flagellin specific chaperone
YP_002391697.1	binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family
YP_002391698.1	converts 1,4-alpha-D-glucans to maltodextrin
YP_002391699.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391700.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391701.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391702.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391703.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3017988, 8057841; Product type m : membrane component
YP_002391704.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12270809; Product type pr : putative regulator
YP_002391705.1	DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown
YP_002391706.1	member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation
YP_002391707.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
YP_002391708.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_002391709.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002391710.1	binds to and inhibits the function of flagella specific ATPase FliI
YP_002391711.1	involved in type III protein export during flagellum assembly
YP_002391712.1	rod/hook and filament chaperone
YP_002391713.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1482109, 8631687; Product type s : structure
YP_002391714.1	interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring
YP_002391715.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
YP_002391716.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002391717.1	with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus
YP_002391718.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_002391719.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
YP_002391720.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
YP_002391721.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14514676, 14766922, 20167175, 90130299, 91154130, 92048476, 9882673, 7534408; Product type r : regulator
YP_002391722.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96324407, 7534408
YP_002391723.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391724.1	catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate
YP_002391725.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16530465; Product type pe : putative enzyme
YP_002391726.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391727.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391728.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391729.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330522, 92049708, 94049122, 10360178, 10612397, 10871403, 2527357; Product type e : enzyme
YP_002391730.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90280700, 91285397, 93367813, 2198248, 2527357; Product type e : enzyme
YP_002391731.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme
YP_002391732.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391733.1	Evidence 2b : Function of strongly homologous gene; Product type pm : putative membrane component
YP_002391734.1	Hsp31 stabilizes early unfolding protein intermediates under severe heat stress
YP_002391735.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865; Product type rc : receptor
YP_002391736.1	induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced
YP_002391737.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391738.1	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ
YP_002391739.1	in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme
YP_002391740.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12077457, 12480884, 12909634, 9579078
YP_002391741.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391742.1	Evidence 6 : Doubtful CDS
YP_002391743.1	catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin
YP_002391744.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391745.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter
YP_002391746.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter
YP_002391747.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8930916; Product type r : regulator
YP_002391748.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 8366034, 11927258, 9709002; Product type e : enzyme
YP_002391749.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 11927258; Product type e : enzyme
YP_002391750.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11927258; Product type e : enzyme
YP_002391751.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391752.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9818149, 11927258, 9709002; Product type e : enzyme
YP_002391753.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7896707, 7984105; Product type rc : receptor
YP_002391754.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391755.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 5332864, 9524262; Product type t : transporter
YP_002391756.1	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
YP_002391757.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391758.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pt : putative transporter
YP_002391759.1	LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB
YP_002391760.1	Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation
YP_002391761.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646
YP_002391762.1	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole
YP_002391763.1	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
YP_002391764.1	catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP
YP_002391765.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391766.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002391767.1	Evidence 7 : Gene remnant
YP_002391768.1	Evidence 6 : Doubtful CDS
YP_002391769.1	Evidence 6 : Doubtful CDS
YP_002391770.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391771.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391772.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391773.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391774.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391775.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391776.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391777.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391778.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391779.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391780.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391781.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391782.1	Evidence 5 : No homology to any previously reported sequences
YP_002391784.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391785.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391787.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391788.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391789.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391790.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391791.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391792.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391793.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391794.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391795.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7519596; Product type h : extrachromosomal origin
YP_002391796.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002391797.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391798.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002391799.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391800.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391801.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391802.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391803.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11850398, 9442027, 8709849; Product type r : regulator
YP_002391804.1	removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
YP_002391805.1	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
YP_002391806.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391807.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391808.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391809.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391810.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391811.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor
YP_002391812.1	Antitoxin that counteracts the effect of the YoeB toxin
YP_002391813.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002391814.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
YP_002391815.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_002391816.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_002391817.1	catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate
YP_002391818.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_002391819.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_002391820.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_002391821.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis
YP_002391822.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98241528; Product type r : regulator
YP_002391823.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150218, 96326333; Product type e : enzyme
YP_002391824.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_002391825.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12171937, 14670712; Product type e : enzyme
YP_002391826.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391827.1	Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14670712; Product type e : enzyme
YP_002391828.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15695667; Product type pe : putative enzyme
YP_002391829.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15695667, 14670712; Product type pt : putative transporter
YP_002391830.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391831.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14670712; Product type pe : putative enzyme
YP_002391832.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10074083, 14670712; Product type e : enzyme
YP_002391833.1	NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose
YP_002391834.1	together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose
YP_002391835.1	WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid
YP_002391836.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme
YP_002391837.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333, 8759852, 11004393; Product type pe : putative enzyme
YP_002391838.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 8759852; Product type pt : putative transporter
YP_002391839.1	WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid
YP_002391840.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme
YP_002391841.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 85006781, 92048476, 93122523, 96326333, 7815923, 8759852; Product type e : enzyme
YP_002391842.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15670885, 96326333; Product type pe : putative enzyme
YP_002391843.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme
YP_002391844.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme
YP_002391845.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme
YP_002391846.1	acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)
YP_002391847.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11371548, 96326333, 8759852; Product type pe : putative enzyme
YP_002391848.1	essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance
YP_002391849.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme
YP_002391850.1	acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium
YP_002391851.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme
YP_002391852.1	Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)
YP_002391853.1	Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis
YP_002391854.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 15090537, 96326333, 8759852, 8763957; Product type lp : lipoprotein
YP_002391855.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002391856.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391857.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391858.1	YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs
YP_002391859.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_002391860.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
YP_002391861.1	contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction
YP_002391862.1	inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine
YP_002391863.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094528, 7940673, 7984428; Product type pf : putative factor
YP_002391864.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391865.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391866.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391867.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate
YP_002391868.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate
YP_002391869.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate
YP_002391870.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12107134, 21450803, 8282725; Product type t : transporter
YP_002391871.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator
YP_002391872.1	response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport
YP_002391873.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391874.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391875.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391876.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391877.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391878.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391879.1	in E. coli K-12 this is in prophage P2 remnant
YP_002391880.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3458177; Product type h : extrachromosomal origin
YP_002391881.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12426340; Product type h : extrachromosomal origin
YP_002391882.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391883.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391884.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391885.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391886.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391887.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391888.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391889.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391890.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9495752; Product type h : extrachromosomal origin
YP_002391891.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391892.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391893.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391894.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391895.1	Evidence 5 : No homology to any previously reported sequences
YP_002391896.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391897.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391898.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391899.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391900.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391901.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391902.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391903.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391904.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391905.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391906.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002391907.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002391908.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391909.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391910.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002391911.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002391912.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391913.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8510152
YP_002391914.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8510152
YP_002391915.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8510152
YP_002391916.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002391917.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2826134
YP_002391918.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2826134; Product type h : extrachromosomal origin
YP_002391919.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3475531; Product type h : extrachromosomal origin
YP_002391920.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391921.1	cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role
YP_002391922.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7772602; Product type r : regulator
YP_002391923.1	Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate
YP_002391924.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76024805, 77192083, 97113438, 7772602; Product type t : transporter
YP_002391925.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002391926.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002391927.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 97113438, 7772602, 8932697; Product type e : enzyme
YP_002391928.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
YP_002391929.1	catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate
YP_002391930.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391931.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391932.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391933.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002391934.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391935.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
YP_002391936.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
YP_002391937.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391938.1	membrane protein conferring nickel and cobalt resistance
YP_002391939.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391940.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002391941.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391942.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002391943.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002391944.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391945.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91080852, 15601724, 2259334; Product type t : transporter
YP_002391946.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002391947.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type pr : putative regulator
YP_002391948.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391949.1	Evidence 6 : Doubtful CDS
YP_002391950.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16428726; Product type pf : putative factor
YP_002391951.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391952.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391953.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391954.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type lp : lipoprotein
YP_002391955.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391956.1	unknown function; when overproduced it confers drug-resistance
YP_002391957.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865, 15322361; Product type rc : receptor
YP_002391958.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11489123; Product type r : regulator
YP_002391959.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391960.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391961.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391962.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391963.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15251200; Product type pt : putative transporter
YP_002391964.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96303506; Product type e : enzyme
YP_002391965.1	component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent
YP_002391966.1	specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7
YP_002391967.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391968.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391969.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391970.1	may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
YP_002391971.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme
YP_002391972.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391973.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391974.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_002391975.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96125233, 1567863, 8550448
YP_002391976.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391977.1	function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain
YP_002391978.1	catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines
YP_002391979.1	ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex
YP_002391980.1	with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains
YP_002391981.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87286407, 92049246, 1719366, 3057628, 3302609, 3600760, 6340108, 6885805, 7012152, 9298646; Product type t : transporter
YP_002391982.1	negative regulator of the mglBAC operon for galactose utilization
YP_002391983.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391984.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391985.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_002391986.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391987.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800; Product type e : enzyme
YP_002391988.1	Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein
YP_002391989.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250419, 94252996, 1315732, 7551055; Product type t : transporter
YP_002391991.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12400704, 1315732; Product type pr : putative regulator
YP_002391992.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002391993.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
YP_002391994.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002391995.1	Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively
YP_002391996.1	activator of nucleoside metabolism
YP_002391997.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002391998.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002391999.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392000.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002392001.1	converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers
YP_002392002.1	phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr
YP_002392003.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter
YP_002392004.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392005.1	Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein
YP_002392006.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392007.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392008.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme
YP_002392009.1	by similarity, Spr seems to have peptidase activity; involved in thermoresistance
YP_002392010.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392011.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392012.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392013.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392014.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392015.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392016.1	Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance
YP_002392017.1	catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA
YP_002392018.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392019.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_002392020.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99296598, 10368163; Product type f : factor
YP_002392021.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392022.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392023.1	nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes
YP_002392024.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 91194558, 95362656, 9914305, 7635817; Product type pe : putative enzyme
YP_002392025.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 9716493, 9770295, 11256948, 11350062, 11843181, 7635817, 9537397; Product type e : enzyme
YP_002392026.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 8842153, 91194558, 95362656, 9716493, 7635817; Product type e : enzyme
YP_002392027.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
YP_002392028.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type f : factor
YP_002392029.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 14532274, 21413853, 95362656, 7635817; Product type t : transporter
YP_002392030.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type t : transporter
YP_002392031.1	ATP-binding protein; required for proper cytochrome c maturation
YP_002392032.1	with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone
YP_002392033.1	small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA
YP_002392034.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
YP_002392035.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
YP_002392036.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
YP_002392037.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96228696, 99395037; Product type f : factor
YP_002392038.1	Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.
YP_002392039.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392040.1	serine protease inhibitor, inhibits trypsin and other proteases
YP_002392041.1	malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
YP_002392042.1	efflux pump for the antibacterial peptide microcin J25
YP_002392043.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12226668, 12517444, 12862460, 14527653, 87057220, 88151899, 92017669, 3536913, 3887409, 7928996; Product type e : enzyme
YP_002392044.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91073391, 93272965, 94252990; Product type r : regulator
YP_002392045.1	catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway
YP_002392046.1	allows for ions and hydrophilic solutes to cross the outer membrane
YP_002392047.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 21206231, 2404948, 7984428; Product type r : regulator
YP_002392048.1	two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF
YP_002392049.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 14651646, 20032358, 21450811, 88227838, 90130299, 92048476, 9209051, 2404948, 8366025; Product type r : regulator
YP_002392050.1	with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism
YP_002392051.1	with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism
YP_002392052.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier
YP_002392053.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier
YP_002392054.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type t : transporter
YP_002392055.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier
YP_002392056.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392057.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392058.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002392059.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392060.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392061.1	negatively supercoils closed circular double-stranded DNA
YP_002392062.1	Involved in ubiquinone biosynthesis
YP_002392063.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor
YP_002392064.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002392065.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
YP_002392066.1	plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases
YP_002392067.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165728, 1537798, 6087316
YP_002392068.1	hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic
YP_002392069.1	catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell
YP_002392070.1	anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor
YP_002392071.1	sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters
YP_002392072.1	anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate
YP_002392073.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392074.1	Evidence 7 : Gene remnant
YP_002392075.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12454498, 16511168, 8550403; Product type pe : putative enzyme
YP_002392076.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392077.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392078.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392079.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392080.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme
YP_002392081.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392082.1	catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose
YP_002392083.1	catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate
YP_002392084.1	Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains
YP_002392085.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392086.1	catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A
YP_002392087.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392088.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392089.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96015440, 15569938; Product type pt : putative transporter
YP_002392090.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96186953, 8626063; Product type e : enzyme
YP_002392091.1	catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate
YP_002392092.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_002392093.1	catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA
YP_002392094.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
YP_002392095.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150206, 96140724, 2666397, 7984428, 8549818, 8764478; Product type e : enzyme
YP_002392096.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392097.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392098.1	member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
YP_002392099.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392100.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392101.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392102.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392103.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392104.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002392105.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392106.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392107.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392108.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392109.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392110.1	shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase
YP_002392111.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392112.1	NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms
YP_002392113.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_002392114.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002392115.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123461, 9882671, 7565112; Product type r : regulator
YP_002392116.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_002392117.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489502; Product type e : enzyme
YP_002392118.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392119.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392120.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392121.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392122.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002392123.1	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate
YP_002392124.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pc : putative carrier
YP_002392125.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme
YP_002392126.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392127.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392128.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392129.1	catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate
YP_002392130.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme
YP_002392131.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392132.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284, 91060556; Product type t : transporter
YP_002392133.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284; Product type t : transporter
YP_002392134.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434; Product type t : transporter
YP_002392135.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 6449635, 8161536, 9298646, 9600841, 9740056; Product type t : transporter
YP_002392136.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4583243, 87308226, 3040734, 9298646; Product type t : transporter
YP_002392137.1	catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate
YP_002392138.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_002392139.1	membrane protein required for colicin V production
YP_002392140.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3040734
YP_002392141.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3040739, 91112811, 92041808, 1989505, 3040734; Product type e : enzyme
YP_002392142.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_002392143.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029016, 3040734, 7678242; Product type pm : putative membrane component
YP_002392144.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_002392145.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 92380957, 92380982, 93123150, 2681152, 2991861, 3029016; Product type pe : putative enzyme
YP_002392146.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90036695, 91035267, 2681152, 2991861, 3029016; Product type e : enzyme
YP_002392147.1	in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein
YP_002392148.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392149.1	FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002392150.1	catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules
YP_002392151.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392152.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392153.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392154.1	D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm
YP_002392155.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_002392156.1	involved in methylation of ribosomal protein L3
YP_002392157.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392158.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392159.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002392160.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002392161.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002392162.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002392163.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002392164.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002392165.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10089421, 20200300, 9489669; Product type e : enzyme
YP_002392166.1	multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate
YP_002392167.1	FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth
YP_002392168.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392169.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15178802, 2840553, 3286621, 91100327, 1987139, 9119048; Product type t : transporter
YP_002392170.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8145644, 15352239; Product type lp : lipoprotein
YP_002392171.1	Evidence 6 : Doubtful CDS
YP_002392172.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392173.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392174.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16689790; Product type e : enzyme
YP_002392175.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12562822; Product type h : extrachromosomal origin
YP_002392176.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392177.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392178.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392179.1	Evidence 5 : No homology to any previously reported sequences
YP_002392180.1	Evidence 5 : No homology to any previously reported sequences
YP_002392181.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392182.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392183.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392184.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392185.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392186.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392187.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392188.1	Evidence 6 : Doubtful CDS
YP_002392189.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392190.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392191.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392192.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392194.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392196.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392197.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002392198.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392199.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392200.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392201.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392202.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002392203.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392204.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392205.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392206.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392207.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392208.1	Evidence 5 : No homology to any previously reported sequences
YP_002392209.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392210.1	Evidence 5 : No homology to any previously reported sequences
YP_002392211.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392212.1	Evidence 5 : No homology to any previously reported sequences
YP_002392213.1	Evidence 5 : No homology to any previously reported sequences
YP_002392214.1	Evidence 5 : No homology to any previously reported sequences
YP_002392215.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392216.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392217.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392218.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392219.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392220.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392221.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392222.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392223.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392224.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392225.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392226.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392227.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392228.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392229.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392230.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392231.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15197250; Product type r : regulator
YP_002392232.1	regulates the synthesis and expression of the dsdXA operon and dadA gene
YP_002392233.1	member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function
YP_002392234.1	catalyzes the formation of pyruvate from serine
YP_002392235.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20378313; Product type pt : putative transporter
YP_002392236.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20378313; Product type t : transporter
YP_002392237.1	response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance
YP_002392238.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14523115, 93173621, 9501520, 10923791, 1289796, 8125343, 9535079; Product type r : regulator
YP_002392239.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392240.1	member of the AEC family of auxin efflux transporters; unknown function
YP_002392241.1	catalyzes the formation of formyl-CoA from oxalyl-CoA
YP_002392242.1	catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA
YP_002392243.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11157960
YP_002392244.1	Evidence 6 : Doubtful CDS
YP_002392245.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; Product type pm : putative membrane component
YP_002392246.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock
YP_002392247.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392248.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type prc : putative receptor
YP_002392249.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type pr : putative regulator
YP_002392250.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392251.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392252.1	metalloprotein
YP_002392253.1	Xaa-Pro aminopeptidase; limited methionine aminopeptidase
YP_002392254.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392255.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392256.1	catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate
YP_002392257.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392258.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392259.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20177822, 20305051, 10712688, 10844693; Product type t : transporter
YP_002392260.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 374403, 8022285, 7007808, 827549, 4563236, 1512211; Product type t : transporter
YP_002392261.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392262.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392263.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392264.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_002392265.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10400599, 7007808, 2201776, 7559336; Product type r : regulator
YP_002392266.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96032385, 7559336; Product type t : transporter
YP_002392267.1	catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation
YP_002392268.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002392269.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392270.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002392271.1	Evidence 6 : Doubtful CDS
YP_002392272.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_002392273.1	interacts with cell division protein FitsZ and may be required to anchor septal ring structure
YP_002392274.1	putative role in sulfur assimilation
YP_002392275.1	CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis
YP_002392276.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter
YP_002392277.1	Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system
YP_002392278.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
YP_002392279.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
YP_002392280.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392281.1	catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide
YP_002392282.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 90264334, 2188958, 7665461; Product type t : transporter
YP_002392283.1	Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import
YP_002392284.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264334, 2188958; Product type t : transporter
YP_002392285.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264335, 2188959, 9298646; Product type t : transporter
YP_002392286.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97385354, 2188959, 7984428, 9241368; Product type pe : putative enzyme
YP_002392287.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
YP_002392288.1	belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component
YP_002392289.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392290.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12900013, 7764507
YP_002392291.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392292.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392293.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 6137479, 87242501, 1903834, 8300522; Product type e : enzyme
YP_002392294.1	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis
YP_002392295.1	activates the transcription of the ethanolamine utilization operon
YP_002392296.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10464203; Product type ps : putative structure
YP_002392297.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002392298.1	catalyzes the formation of acetaldehyde from ethanolamine
YP_002392299.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3905806, 10464203; Product type e : enzyme
YP_002392300.1	ethanolamine utilization protein EutA
YP_002392301.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pt : putative transporter
YP_002392302.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002392303.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pf : putative factor
YP_002392304.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002392305.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002392306.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
YP_002392307.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002392308.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10464203
YP_002392309.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002392310.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002392311.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
YP_002392312.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90230300; Product type e : enzyme
YP_002392313.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002392314.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392315.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392316.1	unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)
YP_002392317.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92374842, 1508040, 1528845; Product type r : regulator
YP_002392318.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12426336, 20158894, 21450803, 79216220, 10692383, 1644752; Product type t : transporter
YP_002392319.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392320.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_002392321.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392322.1	Displays esterase activity toward palmitoyl-CoA and pNP-butyrate
YP_002392323.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392325.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_002392326.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358331, 1885529, 2120198; Product type lp : lipoprotein
YP_002392327.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_002392328.1	negative transcriptional regulator of the gcvTHP operon
YP_002392329.1	bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine
YP_002392330.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392331.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392332.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392333.1	controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP
YP_002392334.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 7721693; Product type t : transporter
YP_002392335.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_002392336.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_002392337.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_002392338.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_002392339.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93107072, 94025037, 94165003, 8212131, 8380170; Product type e : enzyme
YP_002392340.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392341.1	Evidence 6 : Doubtful CDS
YP_002392342.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002392343.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392344.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_002392345.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002392346.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_002392347.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15347755, 12540539; Product type pm : putative membrane component
YP_002392348.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8500884, 3304658, 12540539; Product type pf : putative factor
YP_002392349.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392350.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_002392351.1	with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis
YP_002392352.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392353.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002392354.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_002392355.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392356.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_002392357.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_002392358.1	penicillin-insensitive transglycosylase/transpeptidase
YP_002392359.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392360.1	catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds
YP_002392361.1	enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I
YP_002392362.1	catalyzes the removal of an N-terminal amino acid from a peptide or arylamide
YP_002392363.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10393315; Product type pf : putative factor
YP_002392364.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 20013001, 92283811, 94181532, 11551196, 1317854, 4375562, 8300516; Product type c : carrier
YP_002392365.1	involved in the maturation of iron-sulfur cluster-containing proteins
YP_002392366.1	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins
YP_002392367.1	forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein
YP_002392368.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 11994302, 15153099; Product type f : factor
YP_002392369.1	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
YP_002392370.1	regulates the expression of the iscRSUA operon
YP_002392371.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10393315; Product type pe : putative enzyme
YP_002392372.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6389495, 90202735, 95095968, 10747806, 2138605, 8002619; Product type e : enzyme
YP_002392373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392374.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95020540, 96154950; Product type cp : cell process
YP_002392375.1	putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters
YP_002392376.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392377.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392378.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392379.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392380.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392381.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter
YP_002392382.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392383.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392384.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002392385.1	flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine
YP_002392386.1	indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA
YP_002392387.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226691, 8412694; Product type pr : putative regulator
YP_002392388.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392389.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392390.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002392391.1	YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function
YP_002392392.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12110595; Product type e : enzyme
YP_002392393.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392394.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392395.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8765743, 8880900; Product type c : carrier
YP_002392396.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392397.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_002392398.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_002392399.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_002392400.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_002392401.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_002392402.1	catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins
YP_002392403.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_002392404.1	involved in the reduction of the SoxR iron-sulfur cluster
YP_002392405.1	periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP
YP_002392406.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9159522, 97303092, 99431977, 7768826; Product type f : factor
YP_002392407.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
YP_002392408.1	catalyzes the formation of oxaloacetate from L-aspartate
YP_002392409.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392410.1	facilitates an early step in the assembly of the 50S subunit of the ribosome
YP_002392411.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392412.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12562784; Product type t : transporter
YP_002392413.1	stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit
YP_002392414.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_002392415.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392416.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392417.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12952960, 9388228, 99175138, 10644706; Product type c : carrier
YP_002392418.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392419.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002392420.1	catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome
YP_002392421.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392422.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91219460, 1709493, 2053984, 2118499, 2190187, 8419306; Product type t : transporter
YP_002392423.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7518087; Product type pe : putative enzyme
YP_002392424.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7518087; Product type e : enzyme
YP_002392425.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002392426.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor
YP_002392427.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1906060, 2066329
YP_002392428.1	responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA
YP_002392429.1	with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline
YP_002392430.1	associated with 30S ribosomal subunit; interferes with translation elongation
YP_002392431.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002392432.1	catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_002392433.1	catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis
YP_002392434.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive
YP_002392435.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6396419
YP_002392436.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392437.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392438.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96032391; Product type pm : putative membrane component
YP_002392439.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_002392440.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_002392441.1	Essential for efficient processing of 16S rRNA
YP_002392442.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_002392443.1	with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins
YP_002392444.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392445.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392446.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_002392447.1	catalyzes the phosphorylation of NAD to NADP
YP_002392448.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87259985, 91355307, 95058623, 3037486; Product type cp : cell process
YP_002392449.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2045357; Product type lp : lipoprotein
YP_002392450.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392451.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392452.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_002392453.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392454.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392455.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392456.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392457.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392458.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392459.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392460.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392461.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392462.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392463.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392464.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392465.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392466.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392467.1	Evidence 5 : No homology to any previously reported sequences
YP_002392468.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392469.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392470.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392471.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392472.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392473.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392474.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392475.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392476.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392477.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392478.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392479.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392480.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392481.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392482.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392483.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392484.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392485.1	Evidence 7 : Gene remnant
YP_002392486.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392487.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392488.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392489.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392490.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392491.1	Evidence 6 : Doubtful CDS
YP_002392492.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392493.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392494.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392495.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392496.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392497.1	Evidence 5 : No homology to any previously reported sequences
YP_002392498.1	Evidence 5 : No homology to any previously reported sequences
YP_002392499.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392500.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002392501.1	Evidence 5 : No homology to any previously reported sequences
YP_002392502.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392503.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392504.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392505.1	Evidence 5 : No homology to any previously reported sequences
YP_002392506.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392507.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002392508.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392509.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392510.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392511.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392512.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392513.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392514.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392515.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392516.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392517.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392518.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392519.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392520.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392521.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392522.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392523.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392524.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392525.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392526.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392527.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392528.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392529.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392530.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392531.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392532.1	Evidence 5 : No homology to any previously reported sequences
YP_002392533.1	Evidence 5 : No homology to any previously reported sequences
YP_002392534.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392535.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392536.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392537.1	Evidence 5 : No homology to any previously reported sequences
YP_002392538.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002392539.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392540.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392541.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392542.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392543.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392544.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392545.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392546.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392547.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392548.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002392549.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin
YP_002392550.1	Evidence 5 : No homology to any previously reported sequences
YP_002392551.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392552.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392553.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392554.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392562.1	in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution
YP_002392563.1	catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate
YP_002392564.1	catalyzes the formation of succinate from succinate semialdehyde; NADP dependent
YP_002392565.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
YP_002392566.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94127927, 9685361, 8297211; Product type t : transporter
YP_002392567.1	regulator of gab gene expression
YP_002392568.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392569.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392570.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392571.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme
YP_002392572.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20485613, 93126121, 9643551, 98132400, 99415935, 1480493, 7961433; Product type r : regulator
YP_002392573.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392574.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7961433
YP_002392575.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392576.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392577.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392578.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9218434, 11441020, 8820648; Product type pc : putative carrier
YP_002392579.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
YP_002392580.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002392581.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_002392582.1	with ProWX is involved in the high-affinity uptake of glycine betaine
YP_002392583.1	with ProVX is involved in the high-affinity uptake of glycine betaine
YP_002392584.1	with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine
YP_002392585.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16000740; Product type pt : putative transporter
YP_002392586.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392587.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392588.1	DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB
YP_002392589.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590, 8203018; Product type t : transporter
YP_002392590.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590; Product type t : transporter
YP_002392591.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392592.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392593.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_002392594.1	involved in the first step of glutathione biosynthesis
YP_002392595.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392596.1	YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent
YP_002392597.1	affects carbohydrate metabolism; has regulatory role in many processes
YP_002392598.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002392599.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_002392600.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_002392601.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392602.1	membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan
YP_002392603.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87194727, 1334233, 3553176; Product type t : transporter
YP_002392604.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1100602, 3553176; Product type t : transporter
YP_002392605.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002392606.1	catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate
YP_002392607.1	regulator for glucitol utilization
YP_002392608.1	regulates genes involved in glucitol utilization
YP_002392609.1	catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate
YP_002392610.1	Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon
YP_002392611.1	detoxifies nitric oxide using NADH
YP_002392612.1	catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase
YP_002392613.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12377778, 92255260, 8661925; Product type e : enzyme
YP_002392614.1	involved in electron transport from formate to hydrogen
YP_002392615.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type r : regulator
YP_002392616.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002392617.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type e : enzyme
YP_002392618.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392619.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392620.1	involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE
YP_002392621.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 1625581, 2187144, 7851435; Product type f : factor
YP_002392622.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type e : enzyme
YP_002392623.1	electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate
YP_002392624.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 94170785, 2187144, 8125094; Product type e : enzyme
YP_002392625.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636; Product type m : membrane component
YP_002392626.1	catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3)
YP_002392627.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type c : carrier
YP_002392628.1	regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon
YP_002392629.1	plays a role in hydrogenase nickel cofactor insertion
YP_002392630.1	GTP hydrolase involved in nickel liganding into hydrogenases
YP_002392631.1	HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase
YP_002392632.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 92255260, 1849603; Product type f : factor
YP_002392633.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 9485446, 1849603; Product type e : enzyme
YP_002392634.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20307603, 21557168, 90368529, 92140045, 94018617, 2118503, 2280686; Product type r : regulator
YP_002392635.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392636.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392637.1	This protein performs the mismatch recognition step during the DNA repair process
YP_002392638.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9130712; Product type e : enzyme
YP_002392639.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392640.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392641.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11520622
YP_002392642.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392643.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392644.1	member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function
YP_002392645.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392646.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9694845; Product type pf : putative factor
YP_002392647.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses
YP_002392648.1	outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus
YP_002392649.1	catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins
YP_002392650.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_002392651.1	catalyzes the modification of U13 in tRNA(Glu)
YP_002392652.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_002392653.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_002392654.1	forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein
YP_002392655.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392656.1	converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis
YP_002392657.1	may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ
YP_002392658.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_002392659.1	catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3
YP_002392660.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type pm : putative membrane component
YP_002392661.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_002392662.1	hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide
YP_002392663.1	catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity
YP_002392664.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123838; Product type e : enzyme
YP_002392665.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392666.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002392667.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392668.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002392669.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002392670.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392671.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392672.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392673.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392674.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392675.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392676.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392677.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392678.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392679.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392680.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_002392681.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_002392682.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
YP_002392683.1	MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system
YP_002392684.1	part of the MazF-MazE toxin-antitoxin system; conteracts MazF
YP_002392685.1	(p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP
YP_002392686.1	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]
YP_002392687.1	part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system
YP_002392688.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233700, 9772162, 10762278, 13971911; Product type e : enzyme
YP_002392689.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9772162; Product type e : enzyme
YP_002392690.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278; Product type pt : putative transporter
YP_002392691.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002392692.1	catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp
YP_002392693.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392694.1	putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function
YP_002392695.1	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis
YP_002392696.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392697.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8752353, 8026499; Product type pt : putative transporter
YP_002392698.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193203, 93215657, 8385012; Product type e : enzyme
YP_002392699.1	has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups
YP_002392700.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 89291720, 2553671, 2661535, 2664711, 8385012; Product type e : enzyme
YP_002392701.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
YP_002392702.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2553671, 2664711, 7783647; Product type t : transporter
YP_002392703.1	catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose
YP_002392704.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2664711, 13905785; Product type e : enzyme
YP_002392705.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078, 12738765, 80049526, 2664711; Product type e : enzyme
YP_002392706.1	regulates expression of genes involved in L-fucose utilization
YP_002392707.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21188420, 7704273; Product type pe : putative enzyme
YP_002392708.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7704273; Product type pm : putative membrane component
YP_002392709.1	Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence
YP_002392710.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392711.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15148362, 9278392, 10739946, 10829016; Product type e : enzyme
YP_002392712.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002392713.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392714.1	membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
YP_002392715.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392716.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392717.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392718.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392719.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392720.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392721.1	Evidence 2b : Function of strongly homologous gene; Product type f : factor
YP_002392724.1	Evidence 5 : No homology to any previously reported sequences
YP_002392728.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392731.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392733.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392734.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392735.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392736.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392737.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002392738.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392739.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392740.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002392741.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392742.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12787347, 21348478; Product type e : enzyme
YP_002392743.1	catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis
YP_002392744.1	helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity
YP_002392745.1	helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity
YP_002392746.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193232, 1570301, 3308636, 3534791, 3537960, 8099278; Product type e : enzyme
YP_002392747.1	catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination
YP_002392748.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme
YP_002392749.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392750.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme
YP_002392751.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme
YP_002392752.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_002392753.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002392754.1	member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr
YP_002392755.1	hydrolyzes diadenosine polyphosphate
YP_002392756.1	MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair
YP_002392757.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392758.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392759.1	complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH
YP_002392760.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8300626; Product type pm : putative membrane component
YP_002392761.1	Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1
YP_002392762.1	controls transcription of galETKM
YP_002392763.1	catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding
YP_002392764.1	activates the transcription of the lysA gene encoding diaminopimelate decarboxylase
YP_002392765.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15135544; Product type pe : putative enzyme
YP_002392766.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7030324, 90239116, 91154204, 2836407, 3543693, 6319708; Product type t : transporter
YP_002392767.1	catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate
YP_002392768.1	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
YP_002392769.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_002392770.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392771.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15150243; Product type r : regulator
YP_002392772.1	putative molybdenum cofactor-binding protein; participates in purine salvage
YP_002392773.1	FAD-binding subunit; with XdhA and XdhC participates in purine salvage
YP_002392774.1	iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage
YP_002392775.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392776.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392777.1	catalyzes the formation of pyruvate from 2,3-diaminopropionate
YP_002392778.1	Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases
YP_002392779.1	catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position
YP_002392780.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_002392781.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392782.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392783.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392784.1	with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase
YP_002392785.1	in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS
YP_002392786.1	with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain
YP_002392787.1	with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration
YP_002392788.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20372655, 98213740; Product type pt : putative transporter
YP_002392789.1	Catalyzes the deamination of guanine
YP_002392790.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392791.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002392792.1	unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)
YP_002392793.1	Evidence 6 : Doubtful CDS
YP_002392794.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9098051; Product type t : transporter
YP_002392795.1	catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate
YP_002392796.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002392797.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_002392798.1	5'-3' single-stranded-DNA-specific exonuclease
YP_002392799.1	DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity
YP_002392800.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_002392801.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic
YP_002392802.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392803.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392804.1	physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator
YP_002392805.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002392806.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392807.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140; Product type e : enzyme
YP_002392808.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
YP_002392809.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_002392810.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_002392811.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339425; Product type pe : putative enzyme
YP_002392812.1	Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone
YP_002392813.1	exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide
YP_002392814.1	the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown
YP_002392815.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 412171; Product type cp : cell process
YP_002392816.1	ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function
YP_002392817.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_002392818.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_002392819.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392820.1	specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport
YP_002392821.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392822.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392823.1	Involved in the export of arginine
YP_002392824.1	participates in the regulation of osmotic pressure changes within the cel
YP_002392825.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_002392826.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_002392827.1	NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate
YP_002392828.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392829.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392830.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392831.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392832.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392833.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392834.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392835.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392836.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8353127; Product type t : transporter
YP_002392837.1	TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein
YP_002392838.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392839.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002392840.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1310091; Product type pe : putative enzyme
YP_002392841.1	catalyzes the formation of putrescine from agmatine
YP_002392842.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392843.1	catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis
YP_002392844.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392845.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392846.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002392847.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9182541; Product type t : transporter
YP_002392848.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7984428, 8113204
YP_002392849.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 72060411, 92335461, 4955462, 7867949, 8113204; Product type e : enzyme
YP_002392850.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002392851.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
YP_002392852.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392853.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_002392854.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1676385; Product type t : transporter
YP_002392855.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392856.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392857.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12975589
YP_002392858.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_002392859.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002392860.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392861.1	catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis
YP_002392862.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153
YP_002392863.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392864.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_002392865.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14730969, 20187555, 20316830, 20580749, 21438845, 90046892, 92409600, 9801309, 2001994, 2197596, 9846876; Product type e : enzyme
YP_002392866.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594836, 10493123, 9298646, 9868784; Product type f : factor
YP_002392867.1	Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
YP_002392868.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88029453, 90323001, 3311747; Product type t : transporter
YP_002392869.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 87260820; Product type e : enzyme
YP_002392870.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392871.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002392872.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392873.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11094055; Product type pe : putative enzyme
YP_002392874.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11094055; Product type pe : putative enzyme
YP_002392875.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8675335, 16369033; Product type f : factor
YP_002392876.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 2895103, 11440716; Product type s : structure
YP_002392877.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2869489, 2895103, 1357526, 8096174, 10049807; Product type s : structure
YP_002392878.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2869489, 2895103, 1357526, 10049807; Product type s : structure
YP_002392879.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 8096174, 10049807, 10446050; Product type s : structure
YP_002392880.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1975085, 1357526; Product type f : factor
YP_002392881.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 10049807, 2478891, 10446050; Product type f : factor
YP_002392882.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2897064, 1357526, 12399496, 2572580, 7909802, 9501230; Product type f : factor
YP_002392883.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2882856, 1357526, 2897064; Product type s : structure
YP_002392884.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6140260, 1357526, 10049807; Product type s : structure
YP_002392885.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2656260, 2868893; Product type r : regulator
YP_002392886.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2868893, 1357526; Product type r : regulator
YP_002392887.1	Evidence 5 : No homology to any previously reported sequences
YP_002392888.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392889.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392890.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392891.1	Evidence 6 : Doubtful CDS
YP_002392892.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002392893.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2842312; Product type r : regulator
YP_002392894.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2842311, 2842312; Product type t : transporter
YP_002392895.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3023201; Product type r : regulator
YP_002392896.1	Evidence 5 : No homology to any previously reported sequences
YP_002392897.1	Evidence 6 : Doubtful CDS
YP_002392898.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392899.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392900.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392901.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12057959; Product type r : regulator
YP_002392902.1	Evidence 5 : No homology to any previously reported sequences
YP_002392903.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2695400; Product type pf : putative factor
YP_002392904.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002392905.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002392906.1	iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein
YP_002392907.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392908.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392909.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392910.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392911.1	Evidence 6 : Doubtful CDS
YP_002392912.1	Evidence 5 : No homology to any previously reported sequences
YP_002392913.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392914.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392915.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392916.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392917.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392918.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392919.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392920.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7519596; Product type pf : putative factor
YP_002392921.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002392922.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002392923.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002392924.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type f : factor
YP_002392925.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392926.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392927.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9987116
YP_002392928.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392929.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8253690; Product type e : enzyme
YP_002392930.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8253690; Product type t : transporter
YP_002392931.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021185; Product type t : transporter
YP_002392932.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_002392933.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter
YP_002392934.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter
YP_002392935.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 16484189, 1735705; Product type e : enzyme
YP_002392936.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14729696, 1729218; Product type e : enzyme
YP_002392937.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2549035; Product type e : enzyme
YP_002392938.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7814319; Product type e : enzyme
YP_002392939.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10930752, 7814319; Product type e : enzyme
YP_002392940.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 8051103, 2082146; Product type t : transporter
YP_002392941.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 7715449; Product type t : transporter
YP_002392942.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392943.1	similar to general secretory pathway protein L
YP_002392944.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392945.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392946.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392947.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392948.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002392949.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002392950.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002392951.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002392952.1	part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm
YP_002392953.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392954.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98175453; Product type e : enzyme
YP_002392955.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 1644747; Product type lp : lipoprotein
YP_002392956.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11785976, 21178909, 11283302; Product type t : transporter
YP_002392957.1	catalyzes the formation of malate from glyoxylate and acetyl-CoA
YP_002392958.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392959.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type c : carrier
YP_002392960.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme
YP_002392961.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme
YP_002392962.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 9880556, 8606183; Product type r : regulator
YP_002392963.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392964.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392965.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392966.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392967.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392968.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392969.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392970.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392971.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002392972.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392973.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392974.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392975.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21336523, 21382172, 7775463; Product type t : transporter
YP_002392976.1	catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction
YP_002392977.1	YghU; B2989; one of eight putative glutathione transferase proteins from E. coli
YP_002392978.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 94292472, 8021226; Product type pf : putative factor
YP_002392979.1	plays a role in hydrogenase nickel cofactor insertion
YP_002392980.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292472, 8021226; Product type f : factor
YP_002392981.1	protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC)
YP_002392982.1	involved in hydrogen uptake
YP_002392983.1	HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits
YP_002392984.1	Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2
YP_002392985.1	involved in hydrogen uptake
YP_002392986.1	Evidence 6 : Doubtful CDS
YP_002392987.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392988.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002392989.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12583903; Product type e : enzyme
YP_002392990.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392991.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002392992.1	membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell
YP_002392993.1	membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell
YP_002392994.1	catalyzes the formation of L-homocysteine from cystathionine
YP_002392995.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002392996.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002392997.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15327949; Product type e : enzyme
YP_002392998.1	methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate
YP_002392999.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393000.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002393001.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393002.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393003.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393004.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393005.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002393006.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393007.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393008.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002393009.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88314889, 1557036, 9298646; Product type r : regulator
YP_002393010.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212294, 1557036; Product type e : enzyme
YP_002393011.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002393012.1	YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system
YP_002393013.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393014.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646
YP_002393015.1	response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes
YP_002393016.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21927389; Product type r : regulator
YP_002393017.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393018.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393019.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393020.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96004656, 96217538; Product type c : carrier
YP_002393021.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10493123, 9298646, 9600841, 9868784; Product type e : enzyme
YP_002393022.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393023.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393024.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393025.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393026.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002393027.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002393028.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002393029.1	Displays esterase activity toward palmitoyl-CoA and pNP-butyrate
YP_002393030.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96411758; Product type e : enzyme
YP_002393031.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393032.1	ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose
YP_002393033.1	trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell
YP_002393034.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393035.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393036.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 11534764; Product type e : enzyme
YP_002393037.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 10600454; Product type e : enzyme
YP_002393038.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10600454; Product type pe : putative enzyme
YP_002393039.1	seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine
YP_002393040.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790762, 1314093; Product type t : transporter
YP_002393041.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393042.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002393043.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002393044.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002393045.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002393046.1	DHBP synthase; functions during riboflavin biosynthesis
YP_002393047.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393048.1	Involved in glycogen synthesis. May be involved in glycogen priming
YP_002393049.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393050.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393051.1	catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose
YP_002393052.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
YP_002393053.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412694; Product type pe : putative enzyme
YP_002393054.1	Evidence 6 : Doubtful CDS
YP_002393055.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11274153; Product type pr : putative regulator
YP_002393056.1	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
YP_002393057.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002393058.1	catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin
YP_002393059.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
YP_002393060.1	activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol
YP_002393061.1	Involved in the tartrate degradation pathway
YP_002393062.1	Involved in the tartrate degradation pathway
YP_002393063.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393064.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_002393065.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_002393066.1	synthesizes RNA primers at the replication forks
YP_002393067.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_002393068.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20412902, 99453007, 6269063, 7567469, 8878487, 9489705; Product type e : enzyme
YP_002393069.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002393070.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393071.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 9380671, 9643537, 9190831; Product type r : regulator
YP_002393072.1	catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate
YP_002393073.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11101501
YP_002393074.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89128452, 2515108, 3939708; Product type r : regulator
YP_002393075.1	in Escherichia coli this is the second beta-galactosidase system
YP_002393076.1	in Escherichia coli this is the second beta-galactosidase system
YP_002393077.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393078.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393079.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213393; Product type pe : putative enzyme
YP_002393080.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12840019, 89380266; Product type e : enzyme
YP_002393081.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393082.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393083.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002393084.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393085.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12107143, 2108134; Product type pm : putative membrane component
YP_002393086.1	involved in the import of serine and threonine coupled with the import of sodium
YP_002393087.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393088.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4570160, 83114543, 3038546; Product type e : enzyme
YP_002393089.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
YP_002393090.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83218546, 98190790; Product type t : transporter
YP_002393091.1	regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.
YP_002393092.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393093.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153
YP_002393094.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393095.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393096.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393097.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393098.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393099.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8478329; Product type e : enzyme
YP_002393100.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393101.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393102.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393103.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393104.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393105.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393106.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme
YP_002393107.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12777779, 9484901; Product type e : enzyme
YP_002393108.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme
YP_002393109.1	catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism
YP_002393110.1	involved in the import of threonine and serine in combination with the import of a proton
YP_002393111.1	catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic
YP_002393112.1	regulates the tdcABCDEFG operon which is involved in amino acid degradation
YP_002393113.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 69151449, 9772162; Product type e : enzyme
YP_002393114.1	catalyzes the reduction of tartronate semialdehyde to glycerate
YP_002393115.1	cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate
YP_002393116.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278, 9772162; Product type pt : putative transporter
YP_002393117.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 66096392, 81027430, 9772162, 10762278, 2407727; Product type e : enzyme
YP_002393118.1	transcriptional repressor for the agaZVWA and agaSYBCDI operons
YP_002393119.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 20392444, 10931310, 8932697; Product type e : enzyme
YP_002393120.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport
YP_002393121.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393122.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393123.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393124.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002393125.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689210, 9697096, 14731281, 8932697; Product type e : enzyme
YP_002393126.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
YP_002393127.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport
YP_002393128.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport
YP_002393129.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport
YP_002393130.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10931310; Product type e : enzyme
YP_002393131.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393132.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393133.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393134.1	Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein
YP_002393135.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153
YP_002393136.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393137.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393138.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393139.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393140.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393141.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393142.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002393143.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme
YP_002393144.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme
YP_002393145.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393146.1	tryptophan transporter of high affinity
YP_002393147.1	participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division
YP_002393148.1	lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing
YP_002393149.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87083499, 91198209, 99234021, 99340204, 2432069, 3005122, 6382163, 9008164, 9298646; Product type e : enzyme
YP_002393150.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_002393151.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_002393152.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_002393153.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_002393154.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_002393155.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_002393156.1	catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis
YP_002393157.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393158.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20194819, 21125563, 9020118, 94074540, 9564033, 9644254, 9829959, 99298179, 7556084, 8034620, 8045257, 8244950, 8253068; Product type t : transporter
YP_002393159.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_002393160.1	catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate
YP_002393161.1	inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins
YP_002393162.1	Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit
YP_002393163.1	RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability
YP_002393164.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002393165.1	penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
YP_002393166.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_002393167.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393168.1	involved in the peptidyltransferase reaction during translation
YP_002393169.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91088242, 94146411, 10094780, 387076, 8312607; Product type s : structure
YP_002393170.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94311902, 97284515, 2670911, 8037730, 8312607; Product type e : enzyme
YP_002393171.1	activator of maltose metabolism genes
YP_002393172.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_002393173.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393174.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393175.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter
YP_002393176.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter
YP_002393177.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter
YP_002393178.1	ATP-binding subunit of a putative ABC toluene efflux transporter
YP_002393179.1	YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers
YP_002393180.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12805358; Product type e : enzyme
YP_002393181.1	forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis
YP_002393182.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393183.1	LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system
YP_002393184.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7876255, 9298646, 17056748; Product type pt : putative transporter
YP_002393185.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_002393186.1	YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing
YP_002393187.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88212176, 90136533, 90274974, 95020584, 95181483, 7876255, 8025669, 8444818, 9636714; Product type t : transporter
YP_002393188.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393189.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 95181483, 7876255, 8025669; Product type t : transporter
YP_002393190.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 89083480
YP_002393191.1	glycosyltransferase; polymerizes glycan strands in the peptidoglycan
YP_002393192.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92246944, 98269038, 1575737, 9603997; Product type pe : putative enzyme
YP_002393193.1	sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA
YP_002393194.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393195.1	catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate
YP_002393196.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
YP_002393197.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393198.1	catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein
YP_002393199.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
YP_002393200.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96011396, 9864311, 7592358; Product type t : transporter
YP_002393201.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
YP_002393202.1	Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization
YP_002393203.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12445774, 94293773, 1721886, 3029697, 8022275; Product type f : factor
YP_002393204.1	transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation
YP_002393205.1	forms a direct contact with the tRNA during translation
YP_002393206.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_002393207.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393208.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type pe : putative enzyme
YP_002393209.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8830688, 96165272, 8576051, 8576052, 9740056; Product type e : enzyme
YP_002393210.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15137941, 15225661, 21352996, 96165272, 99431977, 3322223, 8576051; Product type e : enzyme
YP_002393211.1	oxidizes malate to oxaloacetate
YP_002393212.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
YP_002393213.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393214.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393215.1	with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate
YP_002393216.1	with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate
YP_002393217.1	membrane protein AaeX; the gene is a member of the aaeXAB operon
YP_002393218.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489430; Product type r : regulator
YP_002393219.1	responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA
YP_002393220.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10960106; Product type pm : putative membrane component
YP_002393221.1	involved in the processing of the 5'end of 16S rRNA
YP_002393222.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002393223.1	part of cell wall structural complex MreBCD; transmembrane component
YP_002393224.1	Evidence 6 : Doubtful CDS
YP_002393225.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_002393226.1	functions in MreBCD complex in some organisms
YP_002393227.1	Evidence 6 : Doubtful CDS
YP_002393228.1	regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules
YP_002393229.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393230.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002393231.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002393232.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393233.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393234.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393235.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393236.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393237.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
YP_002393238.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393239.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393240.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
YP_002393241.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_002393242.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566, 1459953, 1547773, 2835774, 2837762, 8226664; Product type e : enzyme
YP_002393243.1	Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription
YP_002393244.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15028690, 9073062; Product type e : enzyme
YP_002393245.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393246.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8203018, 11257026, 8407802, 1720861; Product type r : regulator
YP_002393247.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012493, 1720861; Product type lp : lipoprotein
YP_002393248.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94262163, 99449638, 1720861, 8407802; Product type t : transporter
YP_002393249.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393250.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter
YP_002393251.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter
YP_002393252.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter
YP_002393253.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8809753, 8898392; Product type t : transporter
YP_002393254.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393255.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393256.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002393257.1	RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA
YP_002393258.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393259.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8432722
YP_002393260.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8112305, 8432722
YP_002393261.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002393262.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_002393263.1	catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase
YP_002393264.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
YP_002393265.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_002393266.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393267.1	mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators
YP_002393268.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393269.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_002393270.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_002393271.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_002393272.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_002393273.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_002393274.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002393275.1	late assembly protein
YP_002393276.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_002393277.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_002393278.1	binds 5S rRNA along with protein L5 and L25
YP_002393279.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_002393280.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_002393281.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_002393282.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_002393283.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_002393284.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_002393285.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_002393286.1	one of the stabilizing components for the large ribosomal subunit
YP_002393287.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_002393288.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_002393289.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_002393290.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_002393291.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_002393292.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_002393293.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_002393294.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_002393295.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_002393296.1	calcium-binding protein that may be required for the initiation of chromosome replication
YP_002393297.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002393298.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002393299.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002393300.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002393301.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608, 7896718; Product type t : transporter
YP_002393302.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 95204361, 96256608; Product type t : transporter
YP_002393303.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96256608; Product type pt : putative transporter
YP_002393304.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608, 1588814; Product type t : transporter
YP_002393305.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96256608; Product type pt : putative transporter
YP_002393306.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002393307.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002393308.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96099298, 96256608, 7959070; Product type t : transporter
YP_002393309.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95047556, 96256608, 98175453, 1676385, 2661540, 7959070; Product type e : enzyme
YP_002393310.1	iron storage protein
YP_002393311.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8954950, 9889981, 2661540, 8639572; Product type c : carrier
YP_002393312.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10760150, 10419961, 2661540; Product type e : enzyme
YP_002393313.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002393314.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002393315.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_002393316.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_002393317.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_002393318.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_002393319.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_002393320.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393321.1	rotamase
YP_002393322.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393323.1	rotamase
YP_002393324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393325.1	involved in potassium efflux
YP_002393326.1	required for KefB activity
YP_002393327.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393328.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9889164; Product type pe : putative enzyme
YP_002393329.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393330.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2559876; Product type e : enzyme
YP_002393331.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393332.1	Evidence 5 : No homology to any previously reported sequences
YP_002393333.1	complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons
YP_002393334.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393335.1	DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate
YP_002393336.1	aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity
YP_002393337.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92021789, 94095125, 2007139, 2403545, 2546924, 7549107; Product type cp : cell process
YP_002393338.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393339.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 2001362, 2007139, 2190212, 2403545, 2546924, 8130188, 8180197; Product type e : enzyme
YP_002393340.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20509826; Product type pt : putative transporter
YP_002393341.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93062014, 2200672, 2445993, 2543955; Product type e : enzyme
YP_002393342.1	involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations
YP_002393343.1	member of the FNT family of formate and nitrite transporters
YP_002393344.1	multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin
YP_002393345.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393346.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393347.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393348.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393349.1	phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE)
YP_002393350.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393351.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393352.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393353.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393354.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002393355.1	catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate
YP_002393356.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_002393357.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136529, 92262475, 92272672, 2549371, 6300769, 7603433, 8341592; Product type e : enzyme
YP_002393358.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393359.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_002393360.1	type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_002393361.1	outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa
YP_002393362.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393363.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393364.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002393365.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002393366.1	bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits
YP_002393367.1	ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose
YP_002393368.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11553591; Product type r : regulator
YP_002393369.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393370.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9867837, 10675343, 10675344; Product type f : factor
YP_002393371.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_002393372.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20223645; Product type pm : putative membrane component
YP_002393373.1	Evidence 6 : Doubtful CDS
YP_002393374.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_002393375.1	membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR
YP_002393376.1	part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation
YP_002393377.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002393378.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor
YP_002393379.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012482, 8407793; Product type t : transporter
YP_002393380.1	cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake
YP_002393381.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393382.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2678009; Product type ph : phenotype
YP_002393383.1	Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis
YP_002393384.1	involved in high-affinity gluconate transport
YP_002393385.1	cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source
YP_002393386.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 4574689, 4582156, 93139975, 97141270, 98019089, 2845225, 3040894, 7984428, 9045817; Product type t : transporter
YP_002393387.1	amylomaltase; acts to release glucose from maltodextrins
YP_002393388.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033892, 10220320, 10469642, 2845225, 3037809, 3155826, 6283313, 6339728, 6986282, 9009262; Product type e : enzyme
YP_002393389.1	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides
YP_002393390.1	catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester
YP_002393391.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9738023
YP_002393392.1	represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism
YP_002393393.1	protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity
YP_002393394.1	belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine
YP_002393395.1	in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane
YP_002393396.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393397.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393398.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393399.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type ps : putative structure
YP_002393400.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor
YP_002393401.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type ps : putative structure
YP_002393402.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002393403.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor
YP_002393404.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor
YP_002393405.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15213132; Product type s : structure
YP_002393406.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88330897, 91104907, 91236706, 2645169, 2975249, 3047129, 3097003; Product type e : enzyme
YP_002393407.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
YP_002393408.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_002393409.1	catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen
YP_002393410.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_002393411.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_002393412.1	YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP)
YP_002393413.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655507, 9119199, 9135111, 97141270; Product type t : transporter
YP_002393414.1	thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate
YP_002393415.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9135111, 93139975, 9537375, 8655507; Product type r : regulator
YP_002393416.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393417.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493123; Product type pe : putative enzyme
YP_002393418.1	Evidence 6 : Doubtful CDS
YP_002393419.1	YhhY; regulated by the fur regulator; unknown function
YP_002393420.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393421.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393422.1	periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides
YP_002393423.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393424.1	hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate
YP_002393425.1	part of the UgpABCE glycerol-3-phosphate uptake system
YP_002393426.1	with UgpABC is involved in uptake of glycerol-3-phosphate
YP_002393427.1	with UgpEC is involved in the uptake of glycerol-3-phosphate
YP_002393428.1	with UgpACE is involved in the uptake of glycerol-3-phosphate
YP_002393429.1	with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
YP_002393430.1	Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
YP_002393431.1	Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
YP_002393432.1	LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter
YP_002393433.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649683, 3891753, 4077929, 9298646, 9298646; Product type t : transporter
YP_002393434.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393435.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649682, 328304, 3891753, 4077929, 9298646, 10972807; Product type t : transporter
YP_002393436.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393437.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393438.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393439.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393440.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393441.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393442.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_002393443.1	putative ABC transporter, membrane protein
YP_002393444.1	putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions
YP_002393445.1	signal recognition protein receptor; functions in the targeting and insertion of membrane proteins
YP_002393446.1	catalyzes the methylation of 16S rRNA at position G966
YP_002393447.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393448.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393449.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393450.1	P-type ATPase involved in the export of lead, cadmium, zinc and mercury
YP_002393451.1	TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs
YP_002393452.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393453.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12558182, 8752353; Product type t : transporter
YP_002393454.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393455.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393456.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20092861, 10625633, 8939709; Product type e : enzyme
YP_002393457.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12960164, 7934931, 92077434, 7867647; Product type t : transporter
YP_002393458.1	with NikACDE is involved in nickel transport into the cell
YP_002393459.1	with NikABDE is involved in nickel transport into the cell
YP_002393460.1	with NikABCE is involved in nickel transport into the cell
YP_002393461.1	with NikABCD is involved with nickel transport into the cell
YP_002393462.1	Inhibits transcription at high concentrations of nickel
YP_002393463.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393464.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393465.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393466.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393467.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393468.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002393469.1	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis
YP_002393470.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393471.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20074572; Product type e : enzyme
YP_002393472.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393473.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393474.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393475.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87014120; Product type t : transporter
YP_002393476.1	ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
YP_002393477.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 93086426, 93308072, 94203056, 10499297, 10652104, 10931298, 11157932, 1453957, 8506346, 8932299, 9298646, 9405142; Product type f : factor
YP_002393478.1	member of the POT family of peptide transporters; probable proton-dependent peptide transporter function
YP_002393479.1	predicted SAM-dependent methyltransferase
YP_002393480.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92394891, 1325967, 8366062; Product type e : enzyme
YP_002393481.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11591672; Product type pe : putative enzyme
YP_002393482.1	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense
YP_002393483.1	Evidence 6 : Doubtful CDS
YP_002393484.1	Evidence 6 : Doubtful CDS
YP_002393485.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95355341, 7721697; Product type e : enzyme
YP_002393486.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293775, 8022277; Product type lp : lipoprotein
YP_002393487.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022277; Product type pr : putative regulator
YP_002393488.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16275907; Product type e : enzyme
YP_002393489.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11179376, 7768795, 9393841, 9680204, 9157252; Product type t : transporter
YP_002393490.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7768795, 9393841, 9680204; Product type pt : putative transporter
YP_002393491.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002393492.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393493.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393494.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393495.1	with HmuTU is involved in the transport of hemin
YP_002393496.1	inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli
YP_002393497.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8885264, 12071744, 8244952, 8455549, 9298646, 9868784; Product type pf : putative factor
YP_002393498.1	inactive form
YP_002393499.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8244952, 8455549; Product type pm : putative membrane component
YP_002393500.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12399493, 12940989, 14702398; Product type r : regulator
YP_002393501.1	with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds
YP_002393502.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter
YP_002393503.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12446650; Product type r : regulator
YP_002393504.1	regulates genes in response to acid and/or during stationary phase
YP_002393505.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92155241, 92394884, 99406302, 1522060, 1740158, 7764225, 9298646; Product type e : enzyme
YP_002393506.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8163487, 14563563; Product type e : enzyme
YP_002393507.1	cytoplasmic; catalyzes the hydrolysis of trehalose to glucose
YP_002393508.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393509.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393510.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393511.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393512.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002393513.1	in Escherichia coli this protein is involved in flagellar function
YP_002393514.1	Evidence 6 : Doubtful CDS
YP_002393515.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4359651, 13813474; Product type e : enzyme
YP_002393516.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pe : putative enzyme
YP_002393517.1	involved in the transport of C4-dicarboxylates across the membrane
YP_002393518.1	HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli
YP_002393519.1	cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA
YP_002393520.1	catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans
YP_002393521.1	binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP)
YP_002393522.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393523.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme
YP_002393524.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393525.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme
YP_002393526.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor
YP_002393527.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor
YP_002393528.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor
YP_002393529.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393530.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type t : transporter
YP_002393531.1	Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides
YP_002393532.1	DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF
YP_002393533.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7536291; Product type t : transporter
YP_002393534.1	transports peptides consisting of two or three amino acids
YP_002393535.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100289, 92065799, 1702779, 1956284, 7536291, 8527431, 8563629, 9298646, 9600841, 9740056, 10972807; Product type t : transporter
YP_002393536.1	catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide
YP_002393537.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393538.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393539.1	constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine
YP_002393540.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11237876; Product type pe : putative enzyme
YP_002393541.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82119950, 90202748, 2180922, 374979; Product type e : enzyme
YP_002393542.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002393543.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15801772, 11237876, 99030322, 99357626, 9298646, 9811658; Product type e : enzyme
YP_002393544.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393545.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393546.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 90115858, 94293754, 94293756, 99177178, 10696873, 1597410, 1961761, 2404279, 7515185, 8197194, 9405743, 9439003, 9692981; Product type f : factor
YP_002393547.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002393548.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002393549.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393550.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393551.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393552.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6320721; Product type pm : putative membrane component
YP_002393553.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 92366447, 95050816, 6320721; Product type e : enzyme
YP_002393554.1	catalyzes the interconversion of D-xylose to D-xylulose
YP_002393555.1	periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity
YP_002393556.1	with XylFH is part of the high affinity xylose ABC transporter
YP_002393557.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500; Product type t : transporter
YP_002393558.1	Evidence 6 : Doubtful CDS
YP_002393559.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 94316500; Product type r : regulator
YP_002393560.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1544897
YP_002393561.1	periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds
YP_002393562.1	transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis
YP_002393563.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002393564.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20372646, 9826648; Product type r : regulator
YP_002393565.1	NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate
YP_002393566.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21617392
YP_002393567.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393568.1	membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO
YP_002393569.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter
YP_002393570.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter
YP_002393571.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21617392, 95050816, 7961955; Product type e : enzyme
YP_002393572.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate
YP_002393573.1	L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate
YP_002393574.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_002393575.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme
YP_002393576.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393577.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2935393; Product type e : enzyme
YP_002393578.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264431, 91317715, 9315303, 94148228, 2140572, 2531290; Product type f : factor
YP_002393579.1	catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis
YP_002393580.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8387990; Product type pe : putative enzyme
YP_002393581.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393582.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393583.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052139, 92283796, 94131964, 1946374, 3135464, 3142516, 6309813, 9551558; Product type t : transporter
YP_002393584.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90254197, 1964486, 3135464, 6384188, 8300537, 13295236; Product type e : enzyme
YP_002393585.1	Acts as a repressor of the mtlAD operon
YP_002393586.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393587.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393588.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393589.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393590.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002393591.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012541, 11283302, 11785976, 8407843; Product type t : transporter
YP_002393592.1	represses the lctPRD operon
YP_002393593.1	flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration
YP_002393594.1	member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates
YP_002393595.1	catalyzes the O-acetylation of serine
YP_002393596.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002393597.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
YP_002393598.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500, 95024051, 99175138, 11031118, 7937896, 8636094, 9973569; Product type c : carrier
YP_002393599.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393600.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_002393601.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12113939, 21972773; Product type cp : cell process
YP_002393602.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393603.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659689, 2647748; Product type pe : putative enzyme
YP_002393604.1	converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism
YP_002393605.1	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine
YP_002393606.1	catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose
YP_002393607.1	catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core
YP_002393608.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20507564, 92250420, 93239678, 9446588, 1624462, 8478319; Product type e : enzyme
YP_002393609.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250420, 92325067, 93054344, 1624462; Product type e : enzyme
YP_002393610.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393611.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9791168, 9756860, 9792656; Product type e : enzyme
YP_002393612.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250420, 92325067, 9756860; Product type e : enzyme
YP_002393613.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9791168, 9756860, 9792656; Product type e : enzyme
YP_002393614.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002393615.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101922, 92121133, 92210496, 9756860, 1732225; Product type e : enzyme
YP_002393616.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92210496, 92250420, 1447141, 1732225, 7988890; Product type e : enzyme
YP_002393617.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9756860, 1447141, 1732225; Product type e : enzyme
YP_002393618.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
YP_002393619.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_002393620.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_002393621.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_002393622.1	required for 70S ribosome assembly
YP_002393623.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_002393624.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_002393625.1	catalyzes the formation of dUMP from dUTP
YP_002393626.1	FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly
YP_002393627.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002393628.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_002393629.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393630.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 913680, 94334998, 95095962, 1925027, 2158980, 2664418, 8002613, 8057377, 8195095; Product type cp : cell process
YP_002393631.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393632.1	this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+
YP_002393633.1	Essential for recycling GMP and indirectly, cGMP
YP_002393634.1	promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_002393635.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12224635, 89255395, 93266525, 94068533, 2005134, 2549050; Product type e : enzyme
YP_002393636.1	specifically modifies tRNA at position G18
YP_002393637.1	catalyzes branch migration in Holliday junction intermediates
YP_002393638.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91203811, 93106943, 1544582, 2017136, 2254324; Product type t : transporter
YP_002393639.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393640.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393641.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393642.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393643.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393644.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393645.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393646.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393647.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393648.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393649.1	catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides
YP_002393650.1	may be involved in the transport of galactosides-pentoses-hexuronides
YP_002393651.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393652.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393653.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393654.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88298691, 89359178, 9914480, 3003106; Product type lp : lipoprotein
YP_002393655.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393656.1	experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS
YP_002393657.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393658.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393659.1	catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type
YP_002393660.1	cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate
YP_002393661.1	membrane protein regulates uhpT expression
YP_002393662.1	Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph
YP_002393663.1	response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter
YP_002393664.1	with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit
YP_002393665.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2989782, 85242083, 92380929, 2989781; Product type e : enzyme
YP_002393666.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002393667.1	multidrug efflux protein involved in adaptation to low energy shock
YP_002393668.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393669.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393670.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393671.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393672.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356969; Product type pt : putative transporter
YP_002393673.1	Evidence 6 : Doubtful CDS
YP_002393674.1	16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent
YP_002393675.1	with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress
YP_002393676.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393677.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393678.1	FAD/NAD(P)-binding domain
YP_002393679.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type t : transporter
YP_002393680.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme
YP_002393681.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism
YP_002393682.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme
YP_002393683.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 79020349; Product type pr : putative regulator
YP_002393684.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002393685.1	YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins
YP_002393686.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393687.1	negatively supercoils closed circular double-stranded DNA
YP_002393688.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_002393689.1	binds the polymerase to DNA and acts as a sliding clamp
YP_002393690.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_002393691.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_002393692.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_002393693.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393694.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_002393695.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_002393696.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002393697.1	tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan
YP_002393698.1	tryptophan transporter of low affinity
YP_002393699.1	Confers resistance to chloramphenicol
YP_002393700.1	Involved in anaerobic NO protection
YP_002393701.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393702.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766567; Product type e : enzyme
YP_002393703.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393704.1	YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily
YP_002393705.1	might be involved in hypersensitivity to nitrofurzone
YP_002393706.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393707.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393708.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10027967; Product type t : transporter
YP_002393709.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140, 3034860, 3309161; Product type e : enzyme
YP_002393710.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002393711.1	positive regulator of the beta-glucoside operon; transcriptional antiterminator
YP_002393712.1	regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon
YP_002393713.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_002393714.1	Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
YP_002393715.1	part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
YP_002393716.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133909, 2215649, 6321434, 6365894, 9228942, 9298646, 9671506; Product type t : transporter
YP_002393717.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_002393718.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_002393719.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_002393720.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_002393721.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_002393722.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_002393723.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_002393724.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_002393725.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_002393726.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_002393727.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
YP_002393728.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_002393729.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_002393730.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002393731.1	transcriptional repressor of asnA which codes for aspartate-ammonia ligase
YP_002393732.1	catalyzes the formation of asparagine from aspartate and ammonia
YP_002393733.1	contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA
YP_002393734.1	interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase
YP_002393735.1	Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH
YP_002393736.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
YP_002393737.1	with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain
YP_002393738.1	functions to transport ribose at high affinity; forms a complex with RbsA2C2B
YP_002393739.1	periplasmic substrate-binding component of the ATP-dependent ribose transport system
YP_002393740.1	catalyzes the formation of D-ribose 5-phosphate from ribose
YP_002393741.1	DNA-binding transcriptional repressor of ribose metabolism
YP_002393742.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 20218988, 12107133; Product type t : transporter
YP_002393743.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393744.1	Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon
YP_002393745.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393746.1	among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function
YP_002393747.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174741; Product type l : leader peptide
YP_002393748.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_002393749.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92332418, 92380929, 1569580, 3550695, 3897211; Product type e : enzyme
YP_002393750.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_002393751.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_002393752.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
YP_002393753.1	participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate
YP_002393754.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_002393755.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94215709, 7878732, 7925971, 8163020; Product type e : enzyme
YP_002393756.1	single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication
YP_002393757.1	catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation
YP_002393758.1	Evidence 6 : Doubtful CDS
YP_002393759.1	enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation
YP_002393760.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 91154193, 92250497, 99175138, 10489448, 1094461, 10947986, 1561103, 2181145, 2193685, 3891733, 4616096, 4883076, 6098320, 6099324, 7812718, 8098620, 8253691; Product type c : carrier
YP_002393761.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002393762.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_002393763.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92114763, 94245613, 94292435, 10629198, 11024259, 11700352, 11832520, 1722555, 1730666; Product type e : enzyme
YP_002393764.1	Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein
YP_002393765.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 94042873, 11106477, 7559340, 8170390, 8226648; Product type e : enzyme
YP_002393766.1	catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid
YP_002393767.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086930, 90212314, 90337949, 92112804, 92174908, 94018634, 94042873, 7559340; Product type e : enzyme
YP_002393768.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292435, 96032389; Product type e : enzyme
YP_002393769.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 8366065; Product type e : enzyme
YP_002393770.1	catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis
YP_002393771.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12621029, 20044778; Product type t : transporter
YP_002393772.1	catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis
YP_002393773.1	enterobacterial common antigen polymerase
YP_002393774.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086874, 90337949, 92112804; Product type e : enzyme
YP_002393775.1	uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function
YP_002393776.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11222759, 2180918, 12419807, 14749327; Product type pr : putative regulator
YP_002393777.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16766528, 92358234, 15477040; Product type e : enzyme
YP_002393778.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89041586; Product type pe : putative enzyme
YP_002393779.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89098348, 92358234, 3054815, 3062586, 9298646; Product type pe : putative enzyme
YP_002393780.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
YP_002393781.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_002393782.1	catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP
YP_002393783.1	defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly
YP_002393784.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393785.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002393786.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_002393787.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393788.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_002393789.1	YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function
YP_002393790.1	unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
YP_002393791.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393792.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393793.1	responsible for the influx of magnesium ions
YP_002393794.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393795.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393796.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393797.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393798.1	catalyzes the hydrolysis of phosphatidylcholine
YP_002393799.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596, 3027506; Product type t : transporter
YP_002393800.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596; Product type t : transporter
YP_002393801.1	lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates
YP_002393802.1	purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium
YP_002393803.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393804.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90384950, 96303520, 2205852, 2643109; Product type r : regulator
YP_002393805.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_002393806.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393807.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393808.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393809.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9200688; Product type t : transporter
YP_002393810.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002393811.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393812.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393813.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393814.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393815.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_002393816.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393817.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393818.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393819.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393820.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12676709; Product type pe : putative enzyme
YP_002393821.1	catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway
YP_002393822.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393823.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393824.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002393825.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism
YP_002393826.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002393827.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393828.1	YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner
YP_002393829.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_002393830.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393831.1	an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions
YP_002393832.1	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_002393833.1	mediates the export of protein precursors bearing twin-arginine signal peptides
YP_002393834.1	with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane
YP_002393835.1	magnesium dependent; not involved in the Sec-independent protein export system
YP_002393836.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92011415, 92250420, 92261317, 1584020, 12007406; Product type r : regulator
YP_002393837.1	catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol
YP_002393838.1	NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin
YP_002393839.1	FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids
YP_002393840.1	includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids
YP_002393841.1	catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters
YP_002393842.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15103642; Product type pf : putative factor
YP_002393843.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100357, 2243799, 7896723; Product type t : transporter
YP_002393844.1	catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX
YP_002393845.1	in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway
YP_002393846.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis
YP_002393847.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393848.1	catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages
YP_002393849.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12498799, 93264419, 94016574, 94206930, 99298180, 10210188, 1429594, 1740115, 1934062, 8413591, 8494885, 8521518, 9194175, 9298646, 9300489, 9572841, 9600841, 9655827; Product type e : enzyme
YP_002393850.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393851.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393852.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_002393853.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_002393854.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393855.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002393856.1	response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54
YP_002393857.1	sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation
YP_002393858.1	forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme
YP_002393859.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642082, 7783627, 9298646, 9622352; Product type f : factor
YP_002393860.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393861.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393862.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393863.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393864.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393865.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393866.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393867.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393868.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393869.1	RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease
YP_002393870.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_002393871.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393872.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393873.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393874.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393875.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393876.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393877.1	required for the formation of active formate dehydrogenase
YP_002393878.1	cytochrome b556(FDO) component; heme containing
YP_002393879.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91317715, 8522521, 9852007; Product type c : carrier
YP_002393880.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme
YP_002393881.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
YP_002393882.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002393883.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078; Product type e : enzyme
YP_002393884.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90128204, 93374854, 8396120; Product type e : enzyme
YP_002393885.1	catalyzes the formation of L-rhamnulose from L-rhamnose
YP_002393886.1	catalyzes the ATP-dependent phosphorylation of rhamnulose
YP_002393887.1	activates the expression of the rhaBAD operon and rhaT gene
YP_002393888.1	transports L-rhamnose and L-lyxose into the cell
YP_002393889.1	SodA; manganese binding; only present under aerobic conditions; destroys free radicals
YP_002393890.1	transports degraded pectin products into the bacterial cell
YP_002393891.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393892.1	part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors
YP_002393893.1	response regulator in two-component regulatory system with CpxA; part of the envelope stress response system
YP_002393894.1	repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates
YP_002393895.1	member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers
YP_002393896.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_002393897.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91161616, 2002055, 3158524, 8774726, 9298646; Product type t : transporter
YP_002393898.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86008270, 2995360, 3158524; Product type e : enzyme
YP_002393899.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_002393900.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393901.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393902.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393903.1	with UspC and Usp E is involved in resistance to UV radiation
YP_002393904.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93194782, 94092163, 95050480, 95362685, 1400248, 2834327, 7961651, 8449868, 9149148; Product type e : enzyme
YP_002393905.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_002393906.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
YP_002393907.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12629974, 12948772, 14646142, 15004242, 90094250, 92210584, 11039922, 11101882, 11226336, 11964478, 1372899, 2544860, 6998951; Product type t : transporter
YP_002393908.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393909.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
YP_002393910.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_002393911.1	heat shock protein involved in degradation of misfolded proteins
YP_002393912.1	heat shock protein involved in degradation of misfolded proteins
YP_002393913.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9282742, 93285993, 8509333; Product type cp : cell process
YP_002393914.1	negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins
YP_002393915.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_002393916.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002393917.1	member of the NlpC/P60 superfamily of peptidases
YP_002393918.1	when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis
YP_002393919.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87326410, 90148970, 3307782, 6361020, 9843488; Product type e : enzyme
YP_002393920.1	multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
YP_002393921.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component
YP_002393922.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393923.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393924.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393925.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002393926.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
YP_002393927.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90292022, 94209230, 3045098; Product type e : enzyme
YP_002393928.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393929.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393930.1	forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone
YP_002393931.1	similar to transaldolase from Escherichia coli; many organisms have multiple copies
YP_002393932.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 95291446, 7773398; Product type t : transporter
YP_002393933.1	FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site
YP_002393934.1	FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS
YP_002393935.1	involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein
YP_002393936.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95291446, 14673546, 7773398; Product type e : enzyme
YP_002393937.1	FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog
YP_002393938.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002393939.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10456927; Product type pm : putative membrane component
YP_002393940.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_002393941.1	catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis
YP_002393942.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_002393943.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_002393944.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_002393945.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : putative enzyme
YP_002393946.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393947.1	Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA
YP_002393948.1	catalyzes the conversion of NADPH to NADH
YP_002393949.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7730270; Product type e : enzyme
YP_002393950.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393951.1	negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis
YP_002393952.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002393953.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
YP_002393954.1	involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space
YP_002393955.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_002393956.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002393957.1	catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon
YP_002393958.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
YP_002393959.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002393960.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_002393961.1	Modulates Rho-dependent transcription termination
YP_002393962.1	binds directly to 23S ribosomal RNA
YP_002393963.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_002393964.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_002393965.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_002393966.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_002393967.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_002393968.1	in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center
YP_002393969.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_002393970.1	with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate
YP_002393971.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8432721, 94089392, 98298179, 10082377, 9632726; Product type e : enzyme
YP_002393972.1	catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate
YP_002393973.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_002393974.1	binds specifically to the major sigma factor sigma 70; active in stationary phase
YP_002393975.1	can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates
YP_002393976.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_002393977.1	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures
YP_002393978.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393979.1	histone-like DNA-binding protein
YP_002393980.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393981.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98362023, 9694902; Product type pf : putative factor
YP_002393982.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21140164, 89327164, 92255260, 11243806, 2666400; Product type r : regulator
YP_002393983.1	DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein
YP_002393984.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_002393985.1	involved in de novo purine biosynthesis
YP_002393986.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2412207
YP_002393987.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002393988.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
YP_002393989.1	Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle
YP_002393990.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295197, 92112731, 92353108, 2836370, 3049537, 3060852, 3276689, 3290857, 3291954, 7826335; Product type e : enzyme
YP_002393991.1	catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol
YP_002393992.1	regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase
YP_002393993.1	one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity
YP_002393994.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393995.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002393996.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002393997.1	alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family
YP_002393998.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7652212; Product type e : enzyme
YP_002393999.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter
YP_002394000.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter
YP_002394001.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234, 12662934; Product type t : transporter
YP_002394002.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type t : transporter
YP_002394003.1	Converts D-sorbitol-dphosphate to D-fructose-6-phosphate
YP_002394004.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type r : regulator
YP_002394005.1	catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA
YP_002394006.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394007.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive
YP_002394008.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002394009.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394010.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002394011.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394012.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394013.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394014.1	Evidence 6 : Doubtful CDS
YP_002394015.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10986267; Product type pm : putative membrane component
YP_002394016.1	with MalKFE is involved in the transport of maltose into the cell
YP_002394017.1	with MalKGE is involved in maltose transport into the cell
YP_002394018.1	functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis
YP_002394019.1	with malEFG is involved in import of maltose/maltodextrin
YP_002394020.1	porin involved in the transport of maltose and maltodextrins
YP_002394021.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87141162, 2434655, 6086106; Product type pt : putative transporter
YP_002394022.1	catalyzes the formation of 4-hydroxybenzoate from chorismate
YP_002394023.1	catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway
YP_002394024.1	PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA
YP_002394025.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme
YP_002394026.1	Represses a number of genes involved in the response to DNA damage
YP_002394027.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165788; Product type cp : cell process
YP_002394028.1	unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential
YP_002394029.1	Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB
YP_002394030.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme
YP_002394031.1	coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia
YP_002394032.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94089392, 7602590; Product type e : enzyme
YP_002394033.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394034.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394035.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394036.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394037.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394038.1	unwinds double stranded DNA
YP_002394039.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
YP_002394040.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394041.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394042.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_002394043.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_002394044.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10739245, 6376124; Product type e : enzyme
YP_002394045.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394046.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002394047.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002394048.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394049.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394050.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2134335; Product type prc : putative receptor
YP_002394051.1	Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity
YP_002394052.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11972052
YP_002394053.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394054.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_002394055.1	binds to single stranded DNA and PriA helcase facilitate replication restart
YP_002394056.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394057.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394058.1	regulates genes involved in response to oxidative stress
YP_002394059.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91210176, 91360349, 94139656, 9564045, 10207625, 12670967, 1653416, 1708380, 7673113, 8065907, 8306957, 8631739, 8969171, 9019397, 9092651, 9204707; Product type r : regulator
YP_002394060.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394061.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21557160, 11479290; Product type pt : putative transporter
YP_002394062.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394063.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394064.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394065.1	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake
YP_002394066.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14563880; Product type pm : putative membrane component
YP_002394067.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
YP_002394068.1	catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552
YP_002394069.1	part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia
YP_002394070.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94335626, 8057835; Product type c : carrier
YP_002394071.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 8057835; Product type e : enzyme
YP_002394072.1	with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552
YP_002394073.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor
YP_002394074.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor
YP_002394075.1	carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system
YP_002394076.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394077.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394078.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394079.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394080.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394081.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394082.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme
YP_002394083.1	part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family
YP_002394084.1	possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
YP_002394085.1	with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
YP_002394086.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394087.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1587481; Product type pe : putative enzyme
YP_002394088.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type e : enzyme
YP_002394089.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type e : enzyme
YP_002394090.1	with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains
YP_002394091.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019, 10064713, 8576032; Product type t : transporter
YP_002394092.1	involved in rpiB and als operon repression
YP_002394093.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_002394094.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394095.1	required for the use of phosphonates and phosphite as phosphorus sources
YP_002394096.1	PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role
YP_002394097.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700258, 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394098.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394099.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394100.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394101.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394102.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394103.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394104.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002394105.1	may be involved in phosphonate uptake and biodegradation
YP_002394106.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002394107.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter
YP_002394108.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter
YP_002394109.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230
YP_002394110.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9650256, 2155230; Product type pt : putative transporter
YP_002394111.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394112.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394113.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10049386, 12525168, 92165733, 93132799, 9871325, 99376621, 8421314; Product type t : transporter
YP_002394114.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator
YP_002394115.1	response regulator in two-component regulatory system with BasS
YP_002394116.1	with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division
YP_002394117.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12867448; Product type t : transporter
YP_002394118.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : c; Product type r : regulator
YP_002394119.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93186686, 2830169, 4204273, 8383109; Product type e : enzyme
YP_002394120.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90060832, 9108148, 1445207, 2684786, 2830169; Product type r : regulator
YP_002394121.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174747, 88162811, 90248411, 2831880, 3031590, 6329200; Product type e : enzyme
YP_002394122.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394123.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86142617, 88193096, 89255123, 2656658; Product type e : enzyme
YP_002394124.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters
YP_002394125.1	response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration
YP_002394126.1	C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration
YP_002394127.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394128.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394129.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394130.1	class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002394131.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394132.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105022, 92210511, 1370290, 1556085, 4204273; Product type e : enzyme
YP_002394133.1	antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein
YP_002394134.1	regulates the cadBA operon
YP_002394135.1	Evidence 5 : No homology to any previously reported sequences
YP_002394136.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394137.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394138.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002394139.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002394140.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394141.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002394142.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394143.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394144.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394145.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394146.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394147.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394148.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394149.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394150.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394151.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394152.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394153.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394154.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394155.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394156.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394157.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002394158.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394159.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394160.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394161.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394162.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394163.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3053170; Product type pe : putative enzyme
YP_002394164.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394165.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8626329
YP_002394166.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394167.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pe : putative enzyme
YP_002394168.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002394169.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure
YP_002394170.1	catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism
YP_002394171.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394172.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002394173.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394174.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002394175.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10498708
YP_002394176.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394177.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394178.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394179.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394180.1	Evidence 6 : Doubtful CDS
YP_002394181.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394182.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394183.1	Evidence 6 : Doubtful CDS
YP_002394184.1	Evidence 5 : No homology to any previously reported sequences
YP_002394185.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394186.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394187.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394188.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394189.1	Evidence 5 : No homology to any previously reported sequences
YP_002394190.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394191.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394192.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002394193.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002394194.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394195.1	Evidence 5 : No homology to any previously reported sequences
YP_002394196.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002394197.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002394198.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394199.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394200.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394201.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002394202.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002394203.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394204.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002394205.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002394206.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pe : putative enzyme
YP_002394207.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394208.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1370290; Product type pr : putative regulator
YP_002394209.1	two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm
YP_002394210.1	copper binding protein required for copper tolerance; involved in resistance toward heavy metals
YP_002394211.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
YP_002394212.1	catalyzes the formation of fumarate from aspartate
YP_002394213.1	F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
YP_002394214.1	uncharacterized member of the APC superfamily of amino acid transporters; unknown function
YP_002394215.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_002394216.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_002394217.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394218.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394219.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019591, 10629195; Product type pe : putative enzyme
YP_002394220.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_002394221.1	acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex
YP_002394222.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98344100, 9677290; Product type lp : lipoprotein
YP_002394223.1	member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations
YP_002394224.1	lipocalin; globomycin-sensitive outer membrane lipoprotein
YP_002394225.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212899, 97464439, 99421326, 10595535, 6795623, 7041115, 9819201; Product type e : enzyme
YP_002394226.1	in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane
YP_002394227.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_002394228.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_002394229.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_002394230.1	lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002394231.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394232.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394233.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394234.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394235.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
YP_002394236.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_002394237.1	3'-5' exoribonuclease specific for small oligoribonuclotides
YP_002394238.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002394239.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394240.1	possibly involved in cell wall synthesis
YP_002394241.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 87242501, 1594459, 7511774; Product type e : enzyme
YP_002394242.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_002394243.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_002394244.1	Stimulates the elongation of poly(A) tails
YP_002394245.1	involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein
YP_002394246.1	with HflC inhibits proteolysis of lambda cII protein by FtsH
YP_002394247.1	with HflK inhibits proteolysis of lambda cII protein by FtsH
YP_002394248.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394249.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_002394250.1	negatively regulates the transcription of genes upregulated by nitrosative stress
YP_002394251.1	3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs
YP_002394252.1	Specifically methylates the ribose of guanosine 2251 in 23S rRNA
YP_002394253.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394254.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394255.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394256.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394257.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394258.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394259.1	catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA
YP_002394260.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394261.1	in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility
YP_002394262.1	YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo
YP_002394263.1	negative regulator of ulaG and ulaABCDEF
YP_002394264.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644495, 15808744; Product type pe : putative enzyme
YP_002394265.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
YP_002394266.1	involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002394267.1	involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002394268.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization
YP_002394269.1	UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway
YP_002394270.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_002394271.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394272.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_002394273.1	binds single-stranded DNA at the primosome assembly site
YP_002394274.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002394275.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_002394276.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394277.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394278.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394279.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394280.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394281.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394282.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002394283.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394284.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8559074; Product type ps : putative structure
YP_002394285.1	FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YP_002394286.1	involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine
YP_002394287.1	Involved in anaerobic NO protection and iron metabolism
YP_002394288.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394289.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14747727; Product type e : enzyme
YP_002394290.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20088838; Product type pr : putative regulator
YP_002394291.1	periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate
YP_002394292.1	catalyzes the formation of AMP from adenosine-3',5'-bisphosphate
YP_002394293.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pr : putative regulator
YP_002394294.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394295.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394296.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
YP_002394297.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394298.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394299.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394300.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_002394301.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter
YP_002394302.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394303.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394304.1	membrane component of a putative sugar ABC transporter system
YP_002394305.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
YP_002394306.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96404780, 2843822, 7984428, 8808921; Product type e : enzyme
YP_002394307.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394308.1	protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD
YP_002394309.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1761034, 8499452, 10393541; Product type c : carrier
YP_002394310.1	activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions
YP_002394311.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_002394312.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264345, 93302496, 8083158, 8421692; Product type e : enzyme
YP_002394313.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002394314.1	regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon
YP_002394315.1	P-type ATPase involved in magnesium influx
YP_002394316.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12515541, 10493123, 10595546, 9298646; Product type pe : putative enzyme
YP_002394317.1	involved in the allosteric regulation of aspartate carbamoyltransferase
YP_002394318.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_002394319.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002394320.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394321.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394322.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394323.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11115104
YP_002394324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394325.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.
YP_002394326.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394327.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394328.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394329.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_002394330.1	binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_002394331.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_002394332.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394333.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394334.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394335.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12147722; Product type pe : putative enzyme
YP_002394336.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394337.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394338.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394339.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002394340.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094, 6092059; Product type e : enzyme
YP_002394341.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002394342.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394343.1	Part of the FecBCDE citrate-dependent iron (III) transport system
YP_002394344.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2651410; Product type t : transporter
YP_002394345.1	part of the FecBCDE citrate-dependent iron (III) transport system
YP_002394346.1	part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+)
YP_002394347.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90105402, 91072220, 92269759, 2836368; Product type t : transporter
YP_002394348.1	with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon
YP_002394349.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport
YP_002394350.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1849492; Product type r : regulator
YP_002394351.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394352.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394353.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394354.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394355.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394356.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394357.1	Evidence 5 : No homology to any previously reported sequences
YP_002394358.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394359.1	Evidence 5 : No homology to any previously reported sequences
YP_002394360.1	Evidence 5 : No homology to any previously reported sequences
YP_002394361.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394362.1	Evidence 5 : No homology to any previously reported sequences
YP_002394363.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394364.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394365.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9103983, 2661530, 10931336, 10094691; Product type m : membrane component
YP_002394366.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394367.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394368.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394369.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002394370.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394371.1	Evidence 6 : Doubtful CDS
YP_002394372.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394374.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002394375.1	phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway
YP_002394376.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15102328; Product type e : enzyme
YP_002394377.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
YP_002394378.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394379.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394380.1	Evidence 5 : No homology to any previously reported sequences
YP_002394381.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394382.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394383.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11425723; Product type pe : putative enzyme
YP_002394384.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394385.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394386.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394387.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394388.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394389.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394390.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394391.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394392.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394393.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394394.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394395.1	Evidence 6 : Doubtful CDS
YP_002394396.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96367099; Product type pf : putative factor
YP_002394397.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394398.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394399.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15743943; Product type t : transporter
YP_002394400.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394401.1	inversion of on/off regulator of fimA
YP_002394402.1	inversion of on/off regulator of fimA
YP_002394403.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6146599, 6147250, 90220509, 93106965, 2858471, 6123483; Product type s : structure
YP_002394404.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12897022, 11673421, 6147250; Product type s : structure
YP_002394405.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20450729, 90220509, 93155127, 93391362, 1363735, 8104335, 8636962, 9783748; Product type f : factor
YP_002394406.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12842468, 90220509, 1970114; Product type f : factor
YP_002394407.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 92394896, 1970114, 2890081; Product type s : structure
YP_002394408.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 92394896, 2890081; Product type s : structure
YP_002394409.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 93155127, 93391362, 1971261, 2890081, 2900235; Product type s : structure
YP_002394410.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125229, 15516583, 8550444; Product type t : transporter
YP_002394411.1	catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate
YP_002394412.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73203083, 77222076, 14401695; Product type e : enzyme
YP_002394413.1	regulates the expression of uxuBA
YP_002394414.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394415.1	Evidence 6 : Doubtful CDS
YP_002394416.1	inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS
YP_002394417.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394418.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95181377, 7876157; Product type e : enzyme
YP_002394419.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394420.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394421.1	in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown
YP_002394422.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002394423.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394424.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394425.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394426.1	Evidence 5 : No homology to any previously reported sequences
YP_002394427.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394428.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8365476, 7607244, 15654892; Product type e : enzyme
YP_002394429.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3691501, 11106419; Product type pe : putative enzyme
YP_002394430.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394431.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter
YP_002394432.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394433.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394434.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394435.1	involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response
YP_002394436.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8939428; Product type e : enzyme
YP_002394437.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11600708; Product type e : enzyme
YP_002394438.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8939428; Product type e : enzyme
YP_002394439.1	Evidence 5 : No homology to any previously reported sequences
YP_002394440.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394441.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394442.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14696199; Product type pe : putative enzyme
YP_002394443.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394444.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394445.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 89034150, 91317710, 10466731, 2033064, 6213619, 6402709, 8384293; Product type r : regulator
YP_002394446.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002394447.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394448.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394449.1	catalyzes the transfer of phosphoglycerol to the glucan backbone
YP_002394450.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394451.1	acts to load the DnaB helicase onto the initiation site during DNA replication
YP_002394452.1	This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'
YP_002394453.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394454.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002394455.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394456.1	regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin
YP_002394457.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11931550, 14756576, 3323834, 9990318; Product type c : carrier
YP_002394458.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394459.1	16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit
YP_002394460.1	with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_002394461.1	alanine acetyltransferase that specifically acetylates ribosomal protein S18
YP_002394462.1	manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily
YP_002394463.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394464.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394465.1	Evidence 5 : No homology to any previously reported sequences
YP_002394466.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394467.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394468.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394469.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394470.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394471.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394472.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394473.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394474.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394475.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394476.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394477.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394478.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8648624; Product type h : extrachromosomal origin
YP_002394479.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394480.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394481.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002394482.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 8022261, 9439003; Product type h : extrachromosomal origin
YP_002394483.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293754, 94293756, 9439003; Product type h : extrachromosomal origin
YP_002394484.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002394485.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394486.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394487.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394488.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881; Product type h : extrachromosomal origin
YP_002394489.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394490.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394491.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394492.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394493.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394494.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394495.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394496.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394497.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394498.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394499.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394500.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394501.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394502.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394503.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394504.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394505.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394506.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394507.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002394508.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394509.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002394510.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2144037; Product type h : extrachromosomal origin
YP_002394511.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002394512.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394513.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394514.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394515.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14687564; Product type pe : putative enzyme
YP_002394516.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394517.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11230150; Product type f : factor
YP_002394518.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
YP_002394519.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1317380, 8253679, 9298646, 9600841; Product type cp : cell process
YP_002394520.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394521.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394522.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394523.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002394524.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394525.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_002394526.1	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
YP_002394527.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_002394528.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
YP_002394529.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002394530.1	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins
YP_002394531.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2684780
YP_002394532.1	catalyzes the formation of serine from O-phosphoserine
YP_002394533.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_002394534.1	catalyzes the formation of NAD(+) from nicotinamide ribonucleotide
YP_002394535.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394536.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002394537.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_002394538.1	catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan
YP_002394539.1	When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription
YP_002394540.1	pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog
YP_002394541.1	catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate
YP_002394542.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20264525, 20309711, 93194823, 96405618, 8449900; Product type r : regulator
YP_002394543.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3531171, 8449900
YP_002394544.1	response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation
YP_002394545.1	part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation
YP_002394546.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88216172, 2835585, 2984198, 3531171; Product type m : membrane component
YP_002394547.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15028693, 21167794, 21317451, 91008980, 91358353, 92380937, 9514749, 9632255, 2984198, 7565118, 9298646; Product type r : regulator
YP_002394548.1	member of the SPOUT superfamily of methyltransferases
YP_002401008.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401009.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8356112, 2651415, 8320218; Product type e : enzyme
YP_002401010.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401011.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401013.1	Evidence 7 : Gene remnant
YP_002401014.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 375010, 1849492; Product type pe : putative enzyme
YP_002401015.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 375010, 1849492; Product type pe : putative enzyme
YP_002401016.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4313071, 6456229, 7044820, 7042696, 6749806; Product type rc : receptor
YP_002401017.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3275632, 10064136; Product type e : enzyme
YP_002401018.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme
YP_002401019.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme
YP_002401020.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme
YP_002401021.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002401022.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002401023.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401024.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401025.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6514154; Product type m : membrane component
YP_002401026.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6514154; Product type m : membrane component
YP_002401027.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 16514154; Product type t : transporter
YP_002401028.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 16514154; Product type t : transporter
YP_002401029.1	Evidence 6 : Doubtful CDS
YP_002401030.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002401031.1	Evidence 5 : No homology to any previously reported sequences
YP_002401032.1	Evidence 5 : No homology to any previously reported sequences
YP_002401033.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401034.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401035.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401036.1	Evidence 6 : Doubtful CDS
YP_002401037.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 375010, 1849492; Product type pe : putative enzyme
YP_002401038.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002401039.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3029390, 2670941, 10564491; Product type h : extrachromosomal origin
YP_002401040.1	SopB
YP_002401041.1	Evidence 6 : Doubtful CDS
YP_002401042.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401043.1	Evidence 5 : No homology to any previously reported sequences
YP_002401044.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401045.1	Evidence 5 : No homology to any previously reported sequences
YP_002401046.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002401047.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401048.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401049.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401050.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401051.1	Evidence 2b : Function of strongly homologous gene; Product type cp : cell process
YP_002401052.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401053.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401054.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401055.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002401056.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9987116, 10537187; Product type h : extrachromosomal origin
YP_002401057.1	PsiA
YP_002401058.1	Mok; similar to F leading maintenance protein C
YP_002401059.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401060.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401061.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401062.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401063.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995191; Product type f : factor
YP_002401064.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15388431; Product type r : regulator
YP_002401065.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7915817, 6368316, 8807284; Product type e : enzyme
YP_002401066.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817, 2999074; Product type s : structure
YP_002401067.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817, 2564189, 8655498; Product type m : membrane component
YP_002401068.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817; Product type m : membrane component
YP_002401069.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655498; Product type s : structure
YP_002401070.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7915817, 8655498; Product type s : structure
YP_002401071.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002401072.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401073.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401074.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021201, 7915817; Product type lp : lipoprotein
YP_002401075.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8021201; Product type pf : putative factor
YP_002401076.1	similar to VirB4
YP_002401077.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292150; Product type m : membrane component
YP_002401078.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292150, 1355084, 7915817, 2198250; Product type s : structure
YP_002401079.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2198250, 7915817, 2050638, 1355084; Product type s : structure
YP_002401080.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2050638, 7915817, 2198250, 1593622; Product type s : structure
YP_002401081.1	TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell
YP_002401082.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12533481, 1593622, 7915817; Product type m : membrane component
YP_002401083.1	type IV secretion system pilus assembly protein; similar to F plasmid TraF
YP_002401084.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2536655, 7915817; Product type m : membrane component
YP_002401085.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16321931, 2536655, 7915817; Product type pe : putative enzyme
YP_002401086.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8444814, 7899511, 10438776; Product type m : membrane component
YP_002401087.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1348105, 7915817, 2656408; Product type s : structure
YP_002401088.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1348105, 7915817; Product type m : membrane component
YP_002401089.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3323526; Product type m : membrane component
YP_002401090.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1359384, 3323526, 7915817, 2087219, 6995306, 9696748, 1730875, 6238226; Product type m : membrane component
YP_002401091.1	type IV secretion system coupling protein; similar to F plasmid TraD
YP_002401092.1	cleaves origin of transfer and unwinds; oriT relaxase
YP_002401093.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8444800, 7768788, 1916281, 7915817, 2164585; Product type e : enzyme
YP_002401094.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2164585, 1916281, 7915817, 8807284, 1374147, 10876242, 3027040, 2951652; Product type r : regulator
YP_002401095.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401096.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401097.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6261081, 7003300, 3019092, 7029525, 2445727, 2580099, 1865183; Product type r : regulator
YP_002401098.1	RepA
YP_002401099.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401100.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401101.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401102.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7972047, 9009197; Product type m : membrane component
YP_002401103.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3531169, 7972047; Product type m : membrane component
YP_002401104.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401105.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401106.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401107.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002401108.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401109.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401110.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401111.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3034857; Product type m : membrane component
YP_002401112.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2249654, 9743528, 7952189, 8204625; Product type f : factor
YP_002401113.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2249654, 9743528; Product type t : transporter
YP_002401114.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2249654, 7592380; Product type t : transporter
YP_002401115.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401116.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401117.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_002401118.1	Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space
YP_002401119.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12655053, 12761110; Product type e : enzyme
YP_002401120.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12655053, 12761110; Product type e : enzyme
YP_002401121.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12655053, 12761110; Product type t : transporter
YP_002401122.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12655053, 12761110; Product type e : enzyme
YP_002401123.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401124.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401125.1	Evidence 5 : No homology to any previously reported sequences
YP_002401126.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10737659, 2144037, 7868598; Product type lp : lipoprotein
YP_002401127.1	IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats
YP_002401128.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002401129.1	Evidence 6 : Doubtful CDS
YP_002401130.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401131.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002401132.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002401133.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401134.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002401135.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002401136.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002401137.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002401138.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2832386; Product type pe : putative enzyme
YP_002401139.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002401140.1	Evidence 5 : No homology to any previously reported sequences
YP_002401141.1	outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA
YP_002401142.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15992275; Product type e : enzyme
YP_002401143.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15992275